# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Ribosomal_60s PF00428.19 KXZ40800.1 - 0.049 14.2 10.2 0.11 13.1 10.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein HNH_3 PF13392.6 KXZ40801.1 - 0.011 15.5 1.8 0.025 14.3 1.8 1.7 1 1 0 1 1 1 0 HNH endonuclease UBA_4 PF14555.6 KXZ40802.1 - 0.00033 20.4 0.0 0.00088 19.0 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain AAA_33 PF13671.6 KXZ40803.1 - 3.3e-12 46.8 0.5 1.2e-10 41.7 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ40803.1 - 0.00058 20.4 0.0 0.0053 17.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ40803.1 - 0.0063 16.9 0.1 0.011 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KXZ40803.1 - 0.029 14.6 0.0 0.072 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXZ40803.1 - 0.036 13.5 0.1 0.053 13.0 0.1 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KXZ40803.1 - 0.036 13.3 0.1 0.086 12.1 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KXZ40803.1 - 0.079 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ40803.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KXZ40803.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KXZ40803.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 KXZ40803.1 - 0.12 12.8 0.2 0.67 10.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXZ40803.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABM PF03992.16 KXZ40803.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase ABC_tran PF00005.27 KXZ40803.1 - 0.21 12.1 0.0 0.37 11.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter GRP PF07172.11 KXZ40804.1 - 0.023 15.4 14.9 0.053 14.2 14.9 1.6 1 0 0 1 1 1 0 Glycine rich protein family Mito_fiss_reg PF05308.11 KXZ40804.1 - 0.72 9.9 7.8 1.6 8.8 7.8 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator PHD PF00628.29 KXZ40806.1 - 6.8e-09 35.5 0.4 9.9e-09 35.0 0.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXZ40806.1 - 0.07 12.7 0.4 0.13 11.8 0.4 1.5 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_10 PF10058.9 KXZ40806.1 - 0.23 11.2 1.1 0.33 10.7 0.4 1.7 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Prok_Ub PF14454.6 KXZ40807.1 - 0.022 14.4 0.9 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Prokaryotic Ubiquitin Mt_ATP-synt_B PF05405.14 KXZ40807.1 - 0.089 12.4 0.6 0.15 11.7 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FixO PF02433.15 KXZ40807.1 - 0.47 9.9 1.6 0.87 9.0 1.6 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Retrotrans_gag PF03732.17 KXZ40808.1 - 0.012 15.8 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein DUF659 PF04937.15 KXZ40808.1 - 0.07 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) HALZ PF02183.18 KXZ40809.1 - 0.1 12.9 0.5 0.1 12.9 0.5 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper SR-25 PF10500.9 KXZ40809.1 - 0.77 9.3 18.9 0.92 9.1 18.3 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cnn_1N PF07989.11 KXZ40809.1 - 2.4 8.4 0.0 2.4 8.4 0.0 3.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Ank_2 PF12796.7 KXZ40810.1 - 0.0011 19.5 0.8 0.78 10.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ40810.1 - 0.098 13.3 1.0 11 6.7 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Helitron_like_N PF14214.6 KXZ40811.1 - 1.6e-05 25.2 0.0 2.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_2 PF07727.14 KXZ40812.1 - 1.9e-71 240.5 0.0 2.6e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C_2 PF13307.6 KXZ40816.1 - 1.8e-07 31.5 0.0 2.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2735 PF10931.8 KXZ40816.1 - 0.03 15.0 0.0 0.47 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2735) Ribosomal_60s PF00428.19 KXZ40817.1 - 3.4 8.3 11.3 6.9 7.3 3.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein USP8_dimer PF08969.11 KXZ40820.1 - 8.3e-09 35.6 0.0 1e-08 35.4 0.0 1.0 1 0 0 1 1 1 1 USP8 dimerisation domain Pkinase PF00069.25 KXZ40821.1 - 2.2e-10 40.4 0.0 4.2e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ40821.1 - 0.00011 21.6 0.0 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KXZ40821.1 - 0.0041 16.7 0.0 0.0078 15.8 0.0 1.4 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KXZ40821.1 - 0.03 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ40821.1 - 0.1 12.5 5.8 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.11 KXZ40821.1 - 0.23 11.0 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Prog_receptor PF02161.15 KXZ40822.1 - 0.57 8.8 1.4 0.72 8.5 1.4 1.0 1 0 0 1 1 1 0 Progesterone receptor Dam PF05869.11 KXZ40823.1 - 0.04 13.5 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Histone PF00125.24 KXZ40824.1 - 1.9e-22 80.0 4.4 2.6e-22 79.6 4.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ40824.1 - 2.8e-05 24.3 0.1 8.4e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ40824.1 - 0.0019 18.6 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ40824.1 - 0.015 15.4 4.6 0.027 14.5 4.6 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ40824.1 - 0.03 14.0 0.7 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain RNA_pol_Rpc4 PF05132.14 KXZ40824.1 - 6.4 7.2 11.7 13 6.2 11.7 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ank_4 PF13637.6 KXZ40825.1 - 7e-13 48.8 1.5 0.0015 19.1 0.0 6.4 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ40825.1 - 4.3e-11 43.3 0.0 0.00098 19.7 0.0 4.5 2 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ40825.1 - 2e-09 36.9 0.0 1.7 9.5 0.0 6.5 5 1 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXZ40825.1 - 1.3e-05 25.3 0.1 0.41 11.0 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) F-box PF00646.33 KXZ40825.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 F-box domain Ank PF00023.30 KXZ40825.1 - 0.13 12.7 0.1 1.2e+02 3.3 0.0 4.4 5 0 0 5 5 5 0 Ankyrin repeat Defensin_4 PF07936.12 KXZ40825.1 - 7.2 6.6 6.0 63 3.6 0.0 3.5 3 0 0 3 3 3 0 Potassium-channel blocking toxin DUF4219 PF13961.6 KXZ40826.1 - 0.13 12.0 0.8 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) DUF456 PF04306.13 KXZ40828.1 - 0.0087 16.4 2.8 0.01 16.2 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) LrgB PF04172.16 KXZ40828.1 - 0.042 13.4 2.1 0.049 13.1 2.1 1.0 1 0 0 1 1 1 0 LrgB-like family Patched PF02460.18 KXZ40828.1 - 0.079 11.0 2.4 0.093 10.8 2.4 1.0 1 0 0 1 1 1 0 Patched family Histone PF00125.24 KXZ40831.1 - 1.6e-21 77.0 5.7 2.2e-21 76.6 5.7 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ40831.1 - 2.5e-05 24.4 0.1 8.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ40831.1 - 0.0019 18.7 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ40831.1 - 0.029 14.0 0.7 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ40831.1 - 0.038 14.0 6.3 0.074 13.1 6.3 1.5 1 1 0 1 1 1 0 YscO-like protein DUF3391 PF11871.8 KXZ40831.1 - 1.1 9.8 7.7 2.6 8.6 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 KXZ40831.1 - 3.2 7.5 10.4 4.2 7.1 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Histone_H2A_C PF16211.5 KXZ40832.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ40832.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ40832.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phage_CI_C PF16452.5 KXZ40833.1 - 0.04 14.2 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CI repressor C-terminal domain Guanylate_cyc PF00211.20 KXZ40834.1 - 8.4e-22 77.7 0.0 9.3e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NTase_sub_bind PF08780.11 KXZ40836.1 - 0.17 11.8 0.0 0.26 11.3 0.0 1.3 1 1 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like CLTH PF10607.9 KXZ40838.1 - 7.5e-05 22.7 0.0 8.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain TPR_4 PF07721.14 KXZ40838.1 - 0.84 10.4 6.1 1.3 9.8 3.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCHC_3 PF13917.6 KXZ40839.1 - 0.00017 21.4 0.9 0.00042 20.2 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KXZ40839.1 - 0.005 16.9 4.0 0.0081 16.2 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXZ40839.1 - 0.1 12.3 1.0 0.17 11.7 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4614 PF15391.6 KXZ40839.1 - 1.7 8.6 10.3 3.8 7.5 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Nucleo_P87 PF07267.11 KXZ40839.1 - 1.9 7.3 3.1 2.3 7.0 3.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_64 PF16483.5 KXZ40840.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Beta-1,3-glucanase LRR_4 PF12799.7 KXZ40843.1 - 0.0029 18.0 0.0 0.0047 17.3 0.0 1.3 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ40843.1 - 0.0059 16.4 0.1 0.058 13.2 0.1 2.0 1 1 0 1 1 1 1 Leucine rich repeat Histone PF00125.24 KXZ40845.1 - 6e-21 75.2 7.7 9.1e-21 74.6 7.7 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ40845.1 - 2.5e-05 24.5 0.1 8.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ40845.1 - 0.0019 18.6 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ40845.1 - 0.025 14.6 5.7 0.049 13.7 5.6 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ40845.1 - 0.027 14.1 0.6 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ40845.1 - 1.2 9.7 8.7 3.2 8.3 8.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 KXZ40845.1 - 5.1 6.8 10.4 6.8 6.4 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Histone PF00125.24 KXZ40846.1 - 2e-22 80.0 4.4 2.6e-22 79.6 4.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ40846.1 - 2.8e-05 24.3 0.1 8.3e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ40846.1 - 0.0019 18.7 0.0 0.0031 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ40846.1 - 0.014 15.4 4.6 0.029 14.4 4.5 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ40846.1 - 0.027 14.1 0.6 1.3 8.7 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ40846.1 - 1.9 9.0 8.4 5 7.7 8.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) RNA_pol_Rpc4 PF05132.14 KXZ40846.1 - 6.4 7.2 11.6 12 6.3 11.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Dimer_Tnp_hAT PF05699.14 KXZ40847.1 - 2.7e-05 23.9 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Hira PF07569.11 KXZ40850.1 - 6.9e-27 94.6 0.0 9e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split Nup160 PF11715.8 KXZ40850.1 - 0.00068 18.4 0.0 0.00087 18.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Peptidase_C48 PF02902.19 KXZ40853.1 - 9.8e-08 32.1 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain UBA_4 PF14555.6 KXZ40854.1 - 2.8e-05 23.9 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain DUF2749 PF10907.8 KXZ40858.1 - 0.041 14.1 0.6 0.078 13.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF3482 PF11981.8 KXZ40858.1 - 0.13 11.6 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) RT_RNaseH_2 PF17919.1 KXZ40860.1 - 2.5e-32 110.9 0.0 3.6e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ40860.1 - 9.8e-32 109.4 0.0 1.4e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase N36 PF11438.8 KXZ40861.1 - 0.072 12.9 0.2 4.1 7.3 0.2 3.3 3 0 0 3 3 3 0 36-mer N-terminal peptide of the N protein (N36) DUF1990 PF09348.10 KXZ40861.1 - 0.11 12.5 11.9 3.4 7.7 0.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1990) VirionAssem_T7 PF11653.8 KXZ40861.1 - 0.13 12.8 6.7 9 6.9 0.5 3.3 1 1 2 3 3 3 0 Bacteriophage T7 virion assembly protein DUF4147 PF13660.6 KXZ40861.1 - 0.19 11.3 11.7 3.2 7.2 1.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4147) ATP-synt_J PF04911.12 KXZ40861.1 - 0.55 9.9 2.6 21 4.8 0.1 3.2 3 0 0 3 3 3 0 ATP synthase j chain Bacteriocin_II PF01721.18 KXZ40861.1 - 2.5 8.3 8.9 16 5.7 0.5 3.2 3 0 0 3 3 3 0 Class II bacteriocin PhyH PF05721.13 KXZ40864.1 - 4e-06 27.2 0.0 5.6e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) COR PF16095.5 KXZ40865.1 - 1.7e-16 60.6 0.0 2.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain PEPCK_ATP PF01293.20 KXZ40867.1 - 3e-139 464.7 0.0 3.3e-139 464.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KXZ40867.1 - 0.022 14.9 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ40867.1 - 0.054 13.9 0.0 0.069 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXZ40867.1 - 0.22 11.3 0.4 0.55 10.0 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MS_channel PF00924.18 KXZ40868.1 - 0.02 14.5 0.2 0.031 13.8 0.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Peptidase_M16_C PF05193.21 KXZ40869.1 - 0.094 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase M16 inactive domain bMG10 PF17973.1 KXZ40872.1 - 1.3e-13 51.3 0.0 2.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain EGF_2 PF07974.13 KXZ40872.1 - 0.00029 21.1 13.7 0.00051 20.3 13.7 1.4 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 KXZ40872.1 - 0.01 16.1 8.6 0.019 15.3 8.6 1.4 1 0 0 1 1 1 0 EGF-like domain TamB PF04357.13 KXZ40872.1 - 0.04 13.2 0.3 0.78 8.9 0.3 2.2 2 0 0 2 2 2 0 TamB, inner membrane protein subunit of TAM complex Laminin_EGF PF00053.24 KXZ40872.1 - 0.076 13.2 13.5 0.062 13.5 10.5 2.0 1 1 1 2 2 2 0 Laminin EGF domain hEGF PF12661.7 KXZ40872.1 - 0.38 11.5 9.1 0.86 10.3 9.1 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 KXZ40872.1 - 6.3 7.0 18.6 0.23 11.5 12.4 1.9 2 0 0 2 2 2 0 Tenascin EGF domain Peptidase_C48 PF02902.19 KXZ40873.1 - 1.1e-06 28.7 0.0 1.4e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Amidohydro_3 PF07969.11 KXZ40874.1 - 0.029 13.8 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase family Apt1 PF10351.9 KXZ40875.1 - 0.00036 19.5 27.2 0.0005 19.0 27.2 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Miga PF10265.9 KXZ40875.1 - 0.0005 19.2 15.7 0.00059 18.9 15.7 1.1 1 0 0 1 1 1 1 Mitoguardin PI3K_1B_p101 PF10486.9 KXZ40875.1 - 0.0037 15.1 21.5 0.0044 14.9 21.5 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 KXZ40875.1 - 0.0053 15.6 13.0 0.0062 15.4 13.0 1.2 1 0 0 1 1 1 1 Presenilin SPX PF03105.19 KXZ40875.1 - 0.0084 16.1 29.5 0.013 15.4 29.5 1.3 1 0 0 1 1 1 1 SPX domain Ndc1_Nup PF09531.10 KXZ40875.1 - 0.04 12.6 14.3 0.044 12.5 14.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LAP1C PF05609.12 KXZ40875.1 - 0.052 12.6 16.7 0.062 12.4 16.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 KXZ40875.1 - 0.058 11.5 18.1 0.075 11.2 18.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rrn6 PF10214.9 KXZ40875.1 - 0.062 11.8 26.7 0.077 11.5 26.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PNISR PF15996.5 KXZ40875.1 - 0.063 13.6 14.1 0.12 12.7 14.1 1.6 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SOG2 PF10428.9 KXZ40875.1 - 0.066 12.4 24.2 0.078 12.2 24.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein NPR3 PF03666.13 KXZ40875.1 - 0.18 10.5 21.4 0.26 10.0 21.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S64 PF08192.11 KXZ40875.1 - 0.26 9.7 22.8 0.31 9.5 22.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 SSP160 PF06933.11 KXZ40875.1 - 0.39 8.8 30.2 0.77 7.9 30.2 1.6 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mem_trans PF03547.18 KXZ40875.1 - 0.41 9.0 5.9 0.65 8.3 5.9 1.3 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 KXZ40875.1 - 0.41 8.9 12.5 0.61 8.3 12.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXZ40875.1 - 0.45 8.7 15.7 0.56 8.4 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family NST1 PF13945.6 KXZ40875.1 - 1.5 8.9 22.7 2.8 8.0 22.7 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator RAP1 PF07218.11 KXZ40875.1 - 1.7 6.8 33.0 2.2 6.4 33.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) eIF-3c_N PF05470.12 KXZ40875.1 - 1.8 6.8 11.2 2.2 6.5 11.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 KXZ40875.1 - 2 7.7 34.8 0.24 10.7 30.6 1.5 2 0 0 2 2 2 0 BUD22 Raftlin PF15250.6 KXZ40875.1 - 2.1 7.0 12.8 3.2 6.4 12.8 1.3 1 0 0 1 1 1 0 Raftlin FAM220 PF15487.6 KXZ40875.1 - 2.2 7.9 21.7 3.4 7.2 21.7 1.4 1 0 0 1 1 1 0 FAM220 family DUF3246 PF11596.8 KXZ40875.1 - 2.2 7.6 26.2 0.13 11.7 18.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3246) FAM199X PF15814.5 KXZ40875.1 - 2.3 7.2 34.7 3.7 6.5 34.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF4551 PF15087.6 KXZ40875.1 - 2.8 6.7 14.3 3.1 6.5 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CytochromB561_N PF09786.9 KXZ40875.1 - 4.2 6.2 23.1 5.2 5.9 23.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal SLC12 PF03522.15 KXZ40875.1 - 5.5 5.9 12.9 7.6 5.4 12.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 KXZ40875.1 - 6.7 5.5 6.8 11 4.8 6.8 1.5 1 0 0 1 1 1 0 Xrn1 helical domain TonB_N PF16031.5 KXZ40875.1 - 8.2 7.0 19.1 15 6.1 18.0 2.1 1 1 0 1 1 1 0 TonB polyproline region SAPS PF04499.15 KXZ40875.1 - 8.4 5.1 14.3 12 4.6 14.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAP1 PF08601.10 KXZ40875.1 - 8.8 5.9 36.7 16 5.1 36.7 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Actin PF00022.19 KXZ40882.1 - 0.043 12.4 0.0 0.066 11.8 0.0 1.3 1 0 0 1 1 1 0 Actin DDR PF08841.10 KXZ40882.1 - 0.14 11.1 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Histone PF00125.24 KXZ40883.1 - 7.4e-48 162.2 0.2 8.9e-48 162.0 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ40883.1 - 0.0001 22.6 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ40883.1 - 0.00031 20.8 0.1 0.00044 20.3 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ40883.1 - 0.0042 17.3 0.1 0.0059 16.9 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ40883.1 - 0.0082 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LolB PF03550.14 KXZ40884.1 - 0.17 12.0 3.1 0.96 9.5 0.2 2.5 2 1 0 2 2 2 0 Outer membrane lipoprotein LolB XkdW PF09636.10 KXZ40885.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 XkdW protein DUF155 PF02582.14 KXZ40888.1 - 1.2e-17 64.6 0.0 1.4e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ank_2 PF12796.7 KXZ40889.1 - 2.6e-11 43.9 0.0 0.054 14.1 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ40889.1 - 1.8e-09 37.1 0.8 19 6.2 0.0 8.0 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 KXZ40889.1 - 8.6e-09 35.8 0.2 0.32 11.6 0.0 5.9 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ40889.1 - 0.00022 21.4 1.3 45 4.5 0.0 5.5 5 1 1 6 6 6 0 Ankyrin repeats (many copies) Defensin_4 PF07936.12 KXZ40889.1 - 0.31 11.0 4.1 75 3.3 0.0 4.4 4 0 0 4 4 4 0 Potassium-channel blocking toxin Zip PF02535.22 KXZ40890.1 - 0.0018 17.6 0.1 0.002 17.4 0.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4834 PF16118.5 KXZ40890.1 - 0.05 14.6 0.0 0.077 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AA_permease PF00324.21 KXZ40890.1 - 0.078 11.6 0.1 0.091 11.3 0.1 1.0 1 0 0 1 1 1 0 Amino acid permease Peptidase_M11 PF05548.11 KXZ40893.1 - 1.5e-09 37.5 0.0 1.6e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Gametolysin peptidase M11 KDZ PF18758.1 KXZ40894.1 - 2.9e-17 63.1 0.0 3.5e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Adaptin_binding PF10199.9 KXZ40898.1 - 2 9.0 7.2 5.7 7.6 7.2 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 zf-DNA_Pol PF08996.10 KXZ40899.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF5304 PF17230.2 KXZ40900.1 - 0.0019 18.5 0.1 0.0023 18.2 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5304) TetR_N PF00440.23 KXZ40900.1 - 0.16 11.8 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DUF1757 PF08560.10 KXZ40901.1 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) Ank_2 PF12796.7 KXZ40903.1 - 5.2e-05 23.8 0.1 11 6.7 0.0 4.2 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ40903.1 - 0.00011 22.7 1.2 39 5.0 0.0 5.9 5 1 2 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ40903.1 - 0.042 14.2 5.2 46 4.5 0.0 4.6 4 1 0 4 4 4 0 Ankyrin repeats (many copies) ATX_III PF08098.11 KXZ40903.1 - 0.16 12.1 2.1 0.56 10.3 2.1 2.0 1 0 0 1 1 1 0 Anemonia sulcata toxin III family MAPEG PF01124.18 KXZ40904.1 - 1.9e-15 56.9 0.7 2.3e-15 56.6 0.7 1.1 1 0 0 1 1 1 1 MAPEG family Trehalose_PPase PF02358.16 KXZ40907.1 - 8.4e-28 97.1 0.0 1.8e-27 96.0 0.0 1.5 1 1 0 1 1 1 1 Trehalose-phosphatase RT_RNaseH PF17917.1 KXZ40909.1 - 1.2e-31 109.1 0.0 2.2e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KXZ40909.1 - 1.2e-26 92.6 0.0 2.8e-26 91.5 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KXZ40912.1 - 9.9e-33 112.2 0.0 1.1e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ40912.1 - 8.3e-24 83.9 0.0 1.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RLI PF04068.15 KXZ40914.1 - 1.9e-11 43.5 0.0 2.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ribo_biogen_C PF04034.13 KXZ40914.1 - 0.0049 16.6 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal CENP-T_C PF15511.6 KXZ40918.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ40918.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ40918.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ40918.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ40918.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ40918.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ40918.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated tRNA-synt_1 PF00133.22 KXZ40919.1 - 4.8e-10 38.3 0.0 7.4e-10 37.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXZ40919.1 - 2.3e-05 24.4 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA RNA_polI_A34 PF08208.11 KXZ40920.1 - 1 9.4 10.6 1.5 8.8 10.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Helicase_C_2 PF13307.6 KXZ40921.1 - 1.8e-07 31.5 0.0 2.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2735 PF10931.8 KXZ40921.1 - 0.04 14.6 0.0 0.47 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2735) RT_RNaseH_2 PF17919.1 KXZ40924.1 - 2.4e-36 123.8 0.0 9.6e-36 121.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ40924.1 - 1e-33 115.7 0.0 3.4e-33 114.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ40924.1 - 1.7e-33 116.0 0.0 2.7e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KXZ40924.1 - 2e-20 72.6 0.0 5.5e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KXZ40924.1 - 6.1e-17 61.9 0.3 1e-15 58.0 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 KXZ40924.1 - 6.6e-08 32.6 0.0 4e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger Chromo PF00385.24 KXZ40924.1 - 5.3e-07 29.5 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chi-conotoxin PF16981.5 KXZ40926.1 - 0.93 9.8 3.1 1.1 9.6 2.5 1.5 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily Spc24 PF08286.11 KXZ40929.1 - 0.0038 17.4 0.2 0.0066 16.7 0.2 1.5 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 S6OS1 PF15676.5 KXZ40929.1 - 0.033 12.7 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family MerR-DNA-bind PF09278.11 KXZ40929.1 - 0.29 11.7 7.1 0.64 10.6 1.3 3.2 3 0 0 3 3 3 0 MerR, DNA binding ZapB PF06005.12 KXZ40929.1 - 3.7 8.1 7.5 5 7.6 5.6 2.2 2 1 0 2 2 2 0 Cell division protein ZapB Nup54 PF13874.6 KXZ40929.1 - 3.8 7.6 9.3 2.8 8.1 0.5 2.8 3 1 1 4 4 4 0 Nucleoporin complex subunit 54 Histone_H2A_C PF16211.5 KXZ40930.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ40930.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ40930.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ40931.1 - 6e-21 75.2 7.7 9.1e-21 74.6 7.7 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ40931.1 - 2.5e-05 24.5 0.1 8.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ40931.1 - 0.0019 18.6 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ40931.1 - 0.025 14.6 5.7 0.049 13.7 5.6 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ40931.1 - 0.027 14.1 0.6 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ40931.1 - 1.2 9.7 8.7 3.2 8.3 8.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 KXZ40931.1 - 5.1 6.8 10.4 6.8 6.4 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ank_4 PF13637.6 KXZ40932.1 - 4.4e-12 46.3 1.9 0.0028 18.2 0.2 5.3 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ40932.1 - 1.7e-10 41.3 0.5 0.00015 22.3 0.0 3.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ40932.1 - 7.9e-06 25.8 1.9 14 6.6 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KXZ40932.1 - 0.0029 17.9 1.2 12 6.3 0.0 4.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ40934.1 - 1.4e-15 57.4 1.0 0.00013 22.4 0.1 6.1 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ40934.1 - 1.5e-12 47.9 0.5 0.0004 20.9 0.0 3.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ40934.1 - 1.9e-06 28.0 0.8 0.47 10.8 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ40934.1 - 5.5e-05 23.3 0.8 59 4.7 0.0 6.6 7 0 0 7 7 7 0 Ankyrin repeat Sh_2 PF17512.2 KXZ40934.1 - 0.065 13.0 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein F-box PF00646.33 KXZ40934.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF4795 PF16043.5 KXZ40937.1 - 0.19 11.3 0.1 0.33 10.5 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF2786 PF10979.8 KXZ40939.1 - 0.016 15.1 1.3 0.016 15.1 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Helicase_C PF00271.31 KXZ40941.1 - 3e-07 30.8 0.0 4.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BCHF PF07284.11 KXZ40942.1 - 0.019 14.9 4.5 0.025 14.6 4.5 1.1 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) HYR PF02494.16 KXZ40943.1 - 4.4e-07 30.1 8.9 0.0001 22.6 0.1 3.9 4 1 0 4 4 4 2 HYR domain Phage_Orf51 PF06194.11 KXZ40946.1 - 0.033 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 DUF3439 PF11921.8 KXZ40950.1 - 0.0077 16.2 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) P3A PF08727.11 KXZ40951.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Poliovirus 3A protein like Asp_protease_2 PF13650.6 KXZ40955.1 - 0.054 14.1 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Ank_2 PF12796.7 KXZ40957.1 - 1.2e-13 51.4 0.1 3.6e-07 30.7 0.0 3.9 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ40957.1 - 6.9e-07 29.7 3.1 0.019 15.5 0.0 5.2 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ40957.1 - 0.00036 20.8 2.1 38 5.3 0.0 6.2 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 KXZ40957.1 - 0.0044 17.3 1.9 0.066 13.6 0.1 3.4 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ40957.1 - 0.016 15.6 2.4 6.6 7.4 0.1 4.5 3 1 2 5 5 5 0 Ankyrin repeat F-box-like_2 PF13013.6 KXZ40957.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain BACK PF07707.15 KXZ40958.1 - 5e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ40958.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain LRRCT PF01463.24 KXZ40958.1 - 0.32 11.6 4.1 8.4 7.2 0.1 3.9 4 0 0 4 4 4 0 Leucine rich repeat C-terminal domain Aldo_ket_red PF00248.21 KXZ40960.1 - 1e-09 38.1 0.1 0.00096 18.4 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Aminotran_4 PF01063.19 KXZ40960.1 - 0.21 11.4 0.0 0.28 11.0 0.0 1.1 1 0 0 1 1 1 0 Amino-transferase class IV Citrate_synt PF00285.21 KXZ40962.1 - 0.19 10.8 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Helitron_like_N PF14214.6 KXZ40964.1 - 1.5e-12 48.1 0.0 3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Ank_4 PF13637.6 KXZ40966.1 - 1.3e-05 25.6 0.0 0.63 10.7 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ40966.1 - 0.00043 20.5 0.0 9.9 7.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXZ40966.1 - 0.00072 19.8 0.1 0.98 9.8 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ40966.1 - 0.0012 19.4 0.0 0.0046 17.5 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Defensin_4 PF07936.12 KXZ40966.1 - 0.032 14.1 6.3 0.17 11.8 0.3 2.9 3 0 0 3 3 3 0 Potassium-channel blocking toxin RicinB_lectin_2 PF14200.6 KXZ40967.1 - 6.3e-07 30.0 0.0 6.1e-06 26.9 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ40967.1 - 0.011 15.9 0.0 0.2 11.9 0.0 1.9 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain HYR PF02494.16 KXZ40968.1 - 3.8e-13 49.6 11.2 7.8e-07 29.3 0.7 3.7 2 1 1 3 3 3 3 HYR domain Jacalin PF01419.17 KXZ40968.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF11 PF01345.18 KXZ40968.1 - 0.08 13.3 7.8 0.1 12.9 0.8 3.3 3 2 0 3 3 3 0 Domain of unknown function DUF11 KDZ PF18758.1 KXZ40970.1 - 8.9e-25 87.6 0.0 1.1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Dimer_Tnp_hAT PF05699.14 KXZ40971.1 - 0.0067 16.2 0.1 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Ank_3 PF13606.6 KXZ40972.1 - 3.5e-07 30.0 0.7 0.43 11.3 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXZ40972.1 - 7.7e-05 23.2 0.3 2.7 8.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ40972.1 - 0.0023 18.5 0.0 0.33 11.6 0.0 2.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ40972.1 - 0.039 14.3 0.0 3.6 8.0 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Me-amine-dh_L PF02975.14 KXZ40972.1 - 0.045 14.2 1.1 0.073 13.6 1.1 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Helitron_like_N PF14214.6 KXZ40976.1 - 2.2e-05 24.8 0.0 3.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus COPI_C PF06957.11 KXZ40981.1 - 1.7e-27 96.2 0.1 2e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Helitron_like_N PF14214.6 KXZ40982.1 - 2e-13 51.0 0.0 2.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus NopRA1 PF16201.5 KXZ40984.1 - 4.2e-17 62.4 0.0 6.8e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 LRR_6 PF13516.6 KXZ40985.1 - 0.0035 17.3 0.0 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Leucine Rich repeat CUE PF02845.16 KXZ40985.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 CUE domain M20_dimer PF07687.14 KXZ40989.1 - 4.4e-11 42.7 0.0 4.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase dimerisation domain PHD PF00628.29 KXZ40990.1 - 4.9e-12 45.6 3.4 8.6e-12 44.8 3.4 1.4 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 KXZ40990.1 - 0.0042 17.4 0.2 0.0093 16.3 0.2 1.6 1 0 0 1 1 1 1 C1 domain zf-4CXXC_R1 PF10497.9 KXZ40990.1 - 0.062 13.5 2.0 1 9.6 1.6 2.2 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD_2 PF13831.6 KXZ40990.1 - 0.068 12.7 3.1 0.17 11.5 3.1 1.7 1 0 0 1 1 1 0 PHD-finger DUF1345 PF07077.11 KXZ40990.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) zf-RING-like PF08746.11 KXZ40990.1 - 1.1 9.6 3.8 0.49 10.7 0.8 1.9 2 0 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.6 KXZ40990.1 - 1.5 9.2 5.7 3.5 8.0 5.7 1.6 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 KXZ40990.1 - 1.8 8.7 5.3 12 6.1 5.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 KXZ40990.1 - 6.1 6.3 9.3 0.57 9.5 0.7 3.2 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others Use1 PF09753.9 KXZ40992.1 - 0.11 12.2 1.8 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 Membrane fusion protein Use1 DivIC PF04977.15 KXZ40992.1 - 0.19 11.5 4.7 0.74 9.6 0.9 2.7 2 0 0 2 2 2 0 Septum formation initiator DUF1840 PF08895.11 KXZ40992.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) MnmE_helical PF12631.7 KXZ40992.1 - 3 7.9 7.8 2.1 8.5 0.9 2.9 2 1 1 3 3 3 0 MnmE helical domain RVT_2 PF07727.14 KXZ40995.1 - 2.8e-57 194.2 0.0 3.3e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM199X PF15814.5 KXZ40996.1 - 0.57 9.2 2.5 0.94 8.5 2.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X Paramecium_SA PF01508.16 KXZ40997.1 - 0.21 12.1 8.2 0.22 12.0 0.8 3.0 3 0 0 3 3 3 0 Paramecium surface antigen domain PSI PF01437.25 KXZ40997.1 - 0.35 11.4 5.2 1.2 9.7 1.5 2.5 2 1 0 2 2 2 0 Plexin repeat Asp_protease_2 PF13650.6 KXZ40998.1 - 0.00039 21.0 0.1 0.00067 20.3 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXZ40998.1 - 0.024 15.2 0.1 0.041 14.5 0.1 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 KXZ40999.1 - 4.6e-11 42.7 0.0 7.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 KXZ40999.1 - 0.00015 21.4 0.1 0.006 16.2 0.1 2.4 2 0 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) Chlam_PMP PF02415.17 KXZ41001.1 - 1.1 9.9 6.2 18 6.1 0.1 3.0 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TPR_19 PF14559.6 KXZ41002.1 - 0.094 13.2 0.2 0.16 12.5 0.2 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF3294 PF07957.11 KXZ41003.1 - 0.0051 16.6 0.0 0.0059 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF5054 PF16477.5 KXZ41003.1 - 0.047 13.5 0.1 0.055 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) DUF885 PF05960.11 KXZ41003.1 - 0.092 12.4 0.5 0.11 12.2 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) NTPase_I-T PF01931.18 KXZ41004.1 - 1.2e-39 135.7 0.0 4.3e-39 133.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF84 cNMP_binding PF00027.29 KXZ41005.1 - 4.4e-05 23.5 0.1 0.18 11.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain SpecificRecomb PF10136.9 KXZ41008.1 - 0.23 9.7 8.9 0.35 9.1 8.9 1.2 1 0 0 1 1 1 0 Site-specific recombinase PRP3 PF08572.10 KXZ41009.1 - 1.8e-20 73.6 0.0 3.6e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) Na_H_Exchanger PF00999.21 KXZ41010.1 - 5e-14 51.9 1.4 6.1e-14 51.6 1.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family p31comet PF06581.12 KXZ41011.1 - 0.04 13.1 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding YqaJ PF09588.10 KXZ41012.1 - 9.9e-05 22.5 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain FANCI_S2 PF14676.6 KXZ41014.1 - 0.14 12.5 0.1 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 FANCI solenoid 2 3HCDH_RFF PF18321.1 KXZ41015.1 - 0.49 10.9 0.1 0.49 10.9 0.1 2.5 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Transglut_core PF01841.19 KXZ41021.1 - 0.072 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF659 PF04937.15 KXZ41022.1 - 2.6e-41 141.0 0.1 9.9e-41 139.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KXZ41022.1 - 1.3e-06 28.1 0.1 2.8e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region KDZ PF18758.1 KXZ41023.1 - 2.8e-14 53.3 0.1 3.4e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_M1_N PF17900.1 KXZ41027.1 - 4.8e-31 108.4 0.0 6.8e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain SART-1 PF03343.13 KXZ41029.1 - 0.05 12.2 2.5 0.1 11.2 2.5 1.5 1 0 0 1 1 1 0 SART-1 family CCDC53 PF10152.9 KXZ41029.1 - 0.078 13.4 23.7 0.36 11.2 4.5 4.2 4 0 0 4 4 4 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 KXZ41029.1 - 6.4 7.4 41.2 1.6 9.4 13.0 4.6 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-MYND PF01753.18 KXZ41030.1 - 7.8e-12 45.1 8.1 1.2e-11 44.5 8.1 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ41030.1 - 0.24 11.7 5.9 0.39 11.1 5.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MCM_lid PF17855.1 KXZ41031.1 - 7.7e-05 23.0 0.7 0.00013 22.3 0.2 1.7 2 0 0 2 2 2 1 MCM AAA-lid domain HYR PF02494.16 KXZ41033.1 - 2.3e-06 27.9 0.6 3.6e-06 27.2 0.6 1.3 1 0 0 1 1 1 1 HYR domain EGF_3 PF12947.7 KXZ41033.1 - 0.0019 18.3 15.9 0.066 13.4 2.9 3.1 3 0 0 3 3 3 2 EGF domain hEGF PF12661.7 KXZ41033.1 - 0.0077 16.8 5.6 0.44 11.2 0.3 3.3 2 0 0 2 2 2 2 Human growth factor-like EGF cEGF PF12662.7 KXZ41033.1 - 0.017 15.0 1.9 0.017 15.0 1.9 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KXZ41033.1 - 0.39 11.0 14.7 0.52 10.6 1.6 2.6 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KXZ41033.1 - 5.2 7.5 16.5 2 8.8 1.4 3.7 3 1 0 3 3 3 0 Pvs28 EGF domain TIL PF01826.17 KXZ41033.1 - 9 6.6 17.1 3.2 8.1 6.4 2.5 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain DprA_WH PF17782.1 KXZ41035.1 - 0.045 13.9 0.9 0.087 13.0 0.9 1.5 1 0 0 1 1 1 0 DprA winged helix domain BPL_C PF02237.17 KXZ41036.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF676 PF05057.14 KXZ41037.1 - 1.2e-26 93.6 0.0 1.1e-25 90.5 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXZ41037.1 - 3.5e-06 26.9 0.0 9.2e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KXZ41037.1 - 9.8e-06 25.0 1.7 4.7e-05 22.8 1.7 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ41037.1 - 1e-05 25.3 0.6 2.3e-05 24.2 0.6 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ41037.1 - 3.3e-05 24.6 10.5 4e-05 24.3 10.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXZ41037.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KXZ41037.1 - 0.0061 16.4 0.0 0.007 16.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Thioesterase PF00975.20 KXZ41037.1 - 0.0061 16.7 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KXZ41037.1 - 0.014 15.1 0.1 0.037 13.7 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 KXZ41037.1 - 0.016 15.0 1.4 0.16 11.8 0.3 2.1 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_2 PF01674.18 KXZ41037.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_5 PF12695.7 KXZ41037.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF900 PF05990.12 KXZ41037.1 - 0.097 12.2 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 KXZ41037.1 - 0.12 11.7 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) ABC2_membrane PF01061.24 KXZ41039.1 - 0.017 14.5 2.3 0.028 13.9 2.3 1.5 1 0 0 1 1 1 0 ABC-2 type transporter Peptidase_M41 PF01434.18 KXZ41040.1 - 7.4e-07 29.2 0.0 8.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M41 S6PP PF05116.13 KXZ41041.1 - 2.3e-13 50.2 0.0 1.3e-08 34.7 0.0 3.2 3 0 0 3 3 3 3 Sucrose-6F-phosphate phosphohydrolase 3HCDH_RFF PF18321.1 KXZ41044.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.3 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain RVT_1 PF00078.27 KXZ41045.1 - 3.7e-08 33.2 0.0 9.3e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KXZ41045.1 - 0.0017 18.6 0.0 0.0064 16.8 0.0 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 KXZ41045.1 - 0.008 16.0 0.2 0.017 14.9 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Phage_integrase PF00589.22 KXZ41045.1 - 0.034 13.9 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 Phage integrase family Nif11 PF07862.11 KXZ41045.1 - 0.069 13.5 0.2 4.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Nif11 domain PHD PF00628.29 KXZ41045.1 - 0.069 13.0 6.8 0.13 12.1 6.8 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KXZ41045.1 - 0.081 12.8 4.4 0.22 11.4 4.4 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RT_RNaseH_2 PF17919.1 KXZ41045.1 - 0.14 12.2 0.0 0.66 10.0 0.0 2.0 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 KXZ41046.1 - 0.00019 21.0 8.9 0.00033 20.2 8.6 1.5 1 1 0 1 1 1 1 SDA1 zf-CCHC PF00098.23 KXZ41046.1 - 0.0069 16.4 1.6 0.0069 16.4 1.6 1.8 2 0 0 2 2 2 1 Zinc knuckle Cyclin_N PF00134.23 KXZ41049.1 - 2.9e-44 149.9 2.3 6.5e-44 148.7 0.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ41049.1 - 5.5e-33 113.6 0.5 9.8e-33 112.8 0.5 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain FtsH_ext PF06480.15 KXZ41051.1 - 0.014 15.7 0.0 0.045 14.1 0.0 1.8 2 0 0 2 2 2 0 FtsH Extracellular Ank_2 PF12796.7 KXZ41054.1 - 1.4e-06 28.8 0.1 0.16 12.6 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41054.1 - 0.0001 22.5 0.4 1.1e+02 3.9 0.0 6.0 6 0 0 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 KXZ41054.1 - 0.00024 21.6 2.5 5.7 7.6 0.0 4.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) HTH_18 PF12833.7 KXZ41056.1 - 0.032 14.5 0.5 0.16 12.2 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain GST_C_3 PF14497.6 KXZ41057.1 - 2.8e-16 59.5 0.1 1.2e-15 57.5 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXZ41057.1 - 2.8e-09 37.2 0.0 5.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ41057.1 - 2.8e-08 33.9 0.0 5.4e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXZ41057.1 - 5.7e-06 26.7 0.0 9.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ41057.1 - 0.00072 19.5 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXZ41057.1 - 0.0021 18.3 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 KXZ41057.1 - 0.038 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain CHASE3 PF05227.13 KXZ41057.1 - 0.15 12.0 0.1 0.23 11.4 0.1 1.2 1 0 0 1 1 1 0 CHASE3 domain DEAD PF00270.29 KXZ41058.1 - 1.1e-45 155.6 0.0 1.6e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ41058.1 - 6.7e-19 68.3 0.0 1.6e-18 67.0 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ41058.1 - 3.5e-06 27.1 0.0 5.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXZ41058.1 - 0.039 13.7 0.3 0.084 12.6 0.3 1.6 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 KXZ41061.1 - 1.4e-08 34.5 0.0 2.4e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Alpha_TIF PF02232.15 KXZ41065.1 - 0.19 10.8 0.5 0.3 10.2 0.5 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) DUF442 PF04273.13 KXZ41067.1 - 0.11 12.6 0.3 0.22 11.6 0.1 1.6 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Ald_Xan_dh_C2 PF02738.18 KXZ41070.1 - 2.1e-10 39.7 8.3 4e-07 28.9 0.0 3.5 1 1 2 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ribosomal_S21 PF01165.20 KXZ41072.1 - 6.9e-08 32.1 2.4 1.2e-07 31.3 2.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 CvfB_WH PF17783.1 KXZ41072.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 CvfB-like winged helix domain Dynamin_N PF00350.23 KXZ41073.1 - 0.15 12.1 0.3 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Dynamin family MatE PF01554.18 KXZ41074.1 - 2.9e-16 59.5 5.2 2.9e-16 59.5 5.2 1.5 2 0 0 2 2 2 1 MatE zf-MYND PF01753.18 KXZ41075.1 - 9.1e-07 28.9 8.5 2.2e-06 27.6 8.5 1.7 1 0 0 1 1 1 1 MYND finger Rax2 PF12768.7 KXZ41079.1 - 0.033 13.6 0.2 0.057 12.9 0.2 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity JmjC PF02373.22 KXZ41080.1 - 1.5e-06 28.7 0.0 2.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.11 KXZ41080.1 - 0.062 12.6 0.1 0.096 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_8 PF13621.6 KXZ41080.1 - 0.1 12.3 0.3 0.2 11.3 0.1 1.5 2 0 0 2 2 2 0 Cupin-like domain Cupin_2 PF07883.11 KXZ41080.1 - 0.13 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Cupin domain His_biosynth PF00977.21 KXZ41081.1 - 1.8e-18 66.9 0.1 2.3e-16 60.0 0.0 2.0 1 1 1 2 2 2 2 Histidine biosynthesis protein DUF5318 PF17249.2 KXZ41081.1 - 0.15 11.9 0.1 0.55 10.0 0.0 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5318) HATPase_c PF02518.26 KXZ41084.1 - 1.7e-09 38.2 0.3 1.1e-07 32.4 0.3 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXZ41084.1 - 1e-07 31.9 4.4 2.3e-06 27.5 0.2 2.8 2 1 1 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SpoU_sub_bind PF08032.12 KXZ41084.1 - 0.13 12.5 2.3 0.55 10.5 0.1 2.3 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF1682 PF07946.14 KXZ41084.1 - 1.1 8.5 6.3 1.3 8.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TF_Zn_Ribbon PF08271.12 KXZ41085.1 - 0.13 11.8 0.6 0.23 11.0 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF3268 PF11672.8 KXZ41085.1 - 0.25 11.7 0.0 0.39 11.0 0.0 1.2 1 0 0 1 1 1 0 zinc-finger-containing domain RT_RNaseH_2 PF17919.1 KXZ41086.1 - 9.6e-33 112.2 0.0 1.9e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ41086.1 - 3.4e-28 98.0 0.1 6.6e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ41086.1 - 9.4e-20 71.1 0.0 1.8e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KXZ41086.1 - 6.1e-19 67.9 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KXZ41086.1 - 6.3e-16 58.6 0.0 2.2e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain PHD PF00628.29 KXZ41086.1 - 3.4e-08 33.2 1.5 3.4e-08 33.2 1.5 2.4 2 0 0 2 2 2 1 PHD-finger zf-H2C2 PF09337.10 KXZ41086.1 - 0.004 17.3 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DDE_Tnp_IS240 PF13610.6 KXZ41086.1 - 0.0062 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 DDE domain zf-HC5HC2H PF13771.6 KXZ41086.1 - 0.023 14.9 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain rve_3 PF13683.6 KXZ41086.1 - 0.087 12.6 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain FANCL_C PF11793.8 KXZ41086.1 - 0.16 12.2 0.6 0.31 11.3 0.6 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KXZ41086.1 - 0.88 9.9 4.8 4.6 7.6 1.3 2.4 2 0 0 2 2 2 0 RING-like domain Hamartin PF04388.12 KXZ41087.1 - 0.015 14.0 2.4 0.018 13.8 2.4 1.0 1 0 0 1 1 1 0 Hamartin protein zf-C4H2 PF10146.9 KXZ41087.1 - 0.023 15.0 6.0 0.032 14.5 6.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein PKcGMP_CC PF16808.5 KXZ41087.1 - 0.1 12.5 0.6 0.45 10.4 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Leu_zip PF15294.6 KXZ41087.1 - 0.11 12.0 9.5 0.17 11.3 9.5 1.4 1 0 0 1 1 1 0 Leucine zipper ERM PF00769.19 KXZ41087.1 - 3.5 7.4 25.5 5.4 6.8 25.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family EF_assoc_2 PF08356.12 KXZ41088.1 - 1.1e-27 95.8 0.0 1.8e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KXZ41088.1 - 2.8e-14 53.1 0.0 4.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ41088.1 - 5.7e-08 33.0 0.0 1.6e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 KXZ41088.1 - 5.2e-06 26.0 0.0 0.0086 15.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXZ41088.1 - 1.3e-05 25.5 0.3 0.0032 17.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ41088.1 - 0.00092 18.6 0.2 0.015 14.8 0.1 2.4 2 0 0 2 2 2 1 EF hand MMR_HSR1 PF01926.23 KXZ41088.1 - 0.00094 19.2 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXZ41088.1 - 0.0074 15.8 0.1 2.3 7.7 0.0 2.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 KXZ41088.1 - 0.017 14.7 0.4 7.9 6.0 0.0 2.8 2 1 1 3 3 3 0 AAA domain EF-hand_5 PF13202.6 KXZ41088.1 - 0.042 13.4 2.1 0.042 13.4 0.6 1.9 2 0 0 2 2 2 0 EF hand SRPRB PF09439.10 KXZ41088.1 - 0.17 11.3 0.0 7.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RVT_1 PF00078.27 KXZ41089.1 - 2e-05 24.2 0.0 0.0048 16.4 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MAP65_ASE1 PF03999.12 KXZ41090.1 - 2.1e-24 86.2 1.8 4.4e-18 65.3 1.0 2.6 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF4047 PF13256.6 KXZ41090.1 - 0.26 11.5 0.7 0.7 10.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) PS_pyruv_trans PF04230.13 KXZ41092.1 - 1.1e-12 48.5 0.0 1.5e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase UPF0220 PF05255.11 KXZ41095.1 - 3.1e-17 62.6 3.7 3.9e-17 62.3 3.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Phage_holin_5_2 PF16079.5 KXZ41095.1 - 9.8 6.6 8.6 8.8 6.7 0.6 2.3 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V TPP_enzyme_N PF02776.18 KXZ41097.1 - 0.029 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CIA30 PF08547.12 KXZ41099.1 - 2.3e-34 118.7 0.1 3e-34 118.4 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 KXZ41099.1 - 1.3e-05 25.2 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) PHO4 PF01384.20 KXZ41101.1 - 3.1e-107 358.5 26.1 4.1e-107 358.1 26.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF1772 PF08592.11 KXZ41101.1 - 0.0087 16.4 0.8 0.0087 16.4 0.8 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF1772) Ferritin-like PF12902.7 KXZ41101.1 - 0.022 14.7 0.3 0.036 13.9 0.3 1.3 1 0 0 1 1 1 0 Ferritin-like Saf_2TM PF18303.1 KXZ41101.1 - 0.089 12.4 1.5 0.27 10.8 1.5 1.8 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain PET117 PF15786.5 KXZ41101.1 - 0.16 12.3 0.4 0.48 10.7 0.4 1.8 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Ank_2 PF12796.7 KXZ41102.1 - 1.4e-23 83.3 2.4 5.4e-16 59.0 1.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ41102.1 - 1.3e-17 63.3 0.2 0.00049 20.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ41102.1 - 4.9e-17 62.1 0.0 1.9e-08 34.6 0.0 3.1 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41102.1 - 2.3e-15 55.1 0.0 0.0071 16.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXZ41102.1 - 1.9e-13 50.3 1.4 5.2e-08 33.0 0.1 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) GATase_7 PF13537.6 KXZ41102.1 - 0.016 15.1 0.1 33 4.4 0.0 3.0 1 1 1 3 3 3 0 Glutamine amidotransferase domain zf-CCHC_4 PF14392.6 KXZ41103.1 - 0.18 11.6 2.0 0.3 10.8 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 KXZ41104.1 - 1.1e-10 41.4 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KXZ41107.1 - 1.1e-33 115.2 0.0 2.1e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ41107.1 - 1.9e-27 95.6 0.0 4.3e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ41107.1 - 3e-25 89.0 0.0 4.8e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KXZ41107.1 - 5e-14 52.2 1.2 5e-14 52.2 1.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KXZ41107.1 - 1.3e-13 51.2 0.0 5.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KXZ41107.1 - 0.089 13.0 4.3 0.041 14.1 1.4 2.1 2 0 0 2 2 2 0 H2C2 zinc finger PRP1_N PF06424.12 KXZ41111.1 - 0.24 11.8 2.3 0.46 10.9 2.3 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Piwi PF02171.17 KXZ41112.1 - 6.9e-34 117.5 0.0 4.4e-29 101.7 0.0 2.1 2 0 0 2 2 2 2 Piwi domain p450 PF00067.22 KXZ41113.1 - 1.7e-13 50.1 0.0 1.9e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1522 PF07482.11 KXZ41114.1 - 1.3 9.4 5.4 0.46 10.8 0.6 2.1 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1522) Ank_4 PF13637.6 KXZ41115.1 - 1.1e-08 35.4 0.0 0.081 13.5 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41115.1 - 0.00023 21.3 0.0 11 6.9 0.0 5.0 5 1 1 6 6 6 1 Ankyrin repeat Ank_2 PF12796.7 KXZ41115.1 - 0.002 18.7 0.0 1.3 9.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ41115.1 - 0.0039 17.5 0.1 1.5 9.3 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) DUF249 PF03158.13 KXZ41115.1 - 0.092 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Multigene family 530 protein Ank_2 PF12796.7 KXZ41116.1 - 7e-05 23.3 0.0 0.00014 22.4 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41116.1 - 0.00066 20.2 0.4 0.0023 18.5 0.2 2.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41116.1 - 0.04 14.5 0.1 10 7.0 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat Phage_CP76 PF06892.11 KXZ41116.1 - 0.042 13.4 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) Ank_5 PF13857.6 KXZ41116.1 - 0.086 13.2 0.3 15 6.1 0.1 2.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41116.1 - 0.12 12.9 0.3 12 6.5 0.1 2.6 2 1 0 2 2 2 0 Ankyrin repeat DUF2158 PF09926.9 KXZ41116.1 - 0.16 11.7 0.2 6.3 6.6 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized small protein (DUF2158) Spc7 PF08317.11 KXZ41117.1 - 2.3 7.0 12.3 4.1 6.2 12.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein PHD PF00628.29 KXZ41120.1 - 8.8e-08 31.9 8.8 2.2e-07 30.7 8.7 1.7 1 1 1 2 2 2 1 PHD-finger TetR_C_24 PF17932.1 KXZ41120.1 - 0.039 14.2 0.3 0.099 12.9 0.3 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2345 PF10106.9 KXZ41121.1 - 0.018 14.9 0.6 0.029 14.3 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) TetR_C_24 PF17932.1 KXZ41121.1 - 0.02 15.1 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PXA PF02194.15 KXZ41121.1 - 0.1 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 PXA domain DUF5363 PF17320.2 KXZ41121.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5363) Adap_comp_sub PF00928.21 KXZ41122.1 - 3.5e-58 197.1 0.0 5.9e-58 196.3 0.0 1.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family DUF4346 PF14251.6 KXZ41123.1 - 5.6e-36 123.1 0.2 4.6e-23 81.5 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4346) Ank_2 PF12796.7 KXZ41125.1 - 9.7e-05 22.9 0.1 0.0047 17.5 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41125.1 - 0.00013 22.2 0.9 0.57 10.9 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXZ41125.1 - 0.0069 16.7 4.6 0.26 11.6 0.1 3.9 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ41125.1 - 0.018 15.6 0.0 0.099 13.3 0.0 2.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41125.1 - 0.078 13.5 1.9 1.3 9.6 0.3 3.4 2 1 0 2 2 2 0 Ankyrin repeat DUF885 PF05960.11 KXZ41126.1 - 6 6.4 26.1 8.3 5.9 26.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) BetaGal_dom4_5 PF13364.6 KXZ41127.1 - 0.0016 18.9 1.1 0.0026 18.3 1.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain CBM60 PF16841.5 KXZ41127.1 - 0.028 14.8 0.5 0.072 13.5 0.5 1.8 1 1 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Ribosomal_S5 PF00333.20 KXZ41128.1 - 0.27 11.2 45.3 41 4.3 0.2 10.1 10 0 0 10 10 10 0 Ribosomal protein S5, N-terminal domain DUF4515 PF14988.6 KXZ41128.1 - 5.1 6.9 14.3 45 3.8 0.3 5.5 1 1 6 8 8 8 0 Domain of unknown function (DUF4515) DUF1664 PF07889.12 KXZ41129.1 - 0.00095 19.2 4.6 0.15 12.1 1.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) XhlA PF10779.9 KXZ41129.1 - 0.0025 18.0 0.5 3.5 7.9 0.0 3.3 2 1 1 3 3 3 1 Haemolysin XhlA DUF16 PF01519.16 KXZ41129.1 - 0.0045 17.5 0.3 4.3 7.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 KXZ41129.1 - 0.019 15.4 2.2 5.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Snapin/Pallidin DUF812 PF05667.11 KXZ41129.1 - 0.077 11.9 3.8 2.9 6.7 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF812) NPV_P10 PF05531.12 KXZ41129.1 - 0.088 13.3 6.5 0.39 11.2 0.9 3.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein GOLGA2L5 PF15070.6 KXZ41129.1 - 0.099 11.3 6.4 0.65 8.6 1.7 2.3 1 1 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 ZapB PF06005.12 KXZ41129.1 - 0.1 13.0 4.9 0.25 11.8 2.6 2.7 2 1 0 2 2 2 0 Cell division protein ZapB KxDL PF10241.9 KXZ41129.1 - 0.12 12.7 2.5 6.7 7.1 0.1 2.7 3 0 0 3 3 2 0 Uncharacterized conserved protein SlyX PF04102.12 KXZ41129.1 - 0.15 12.7 8.6 0.43 11.2 1.1 3.8 3 1 0 3 3 3 0 SlyX MtrG PF04210.13 KXZ41129.1 - 0.18 11.7 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G HOOK PF05622.12 KXZ41129.1 - 0.23 9.5 1.7 0.41 8.7 0.1 1.8 2 0 0 2 2 2 0 HOOK protein Tropomyosin_1 PF12718.7 KXZ41129.1 - 0.25 11.5 9.6 4 7.6 6.7 2.7 2 1 0 2 2 2 0 Tropomyosin like DUF826 PF05696.11 KXZ41129.1 - 0.31 11.1 0.1 0.31 11.1 0.1 3.0 2 1 0 2 2 1 0 Protein of unknown function (DUF826) Syntaxin PF00804.25 KXZ41129.1 - 0.38 10.4 6.1 0.91 9.2 1.0 2.4 2 0 0 2 2 2 0 Syntaxin DUF724 PF05266.14 KXZ41129.1 - 0.6 9.9 4.8 1.9 8.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 KXZ41129.1 - 0.6 10.4 7.3 3.6 7.9 2.5 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 KXZ41129.1 - 0.73 9.9 4.0 2 8.4 0.4 2.9 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 KXZ41129.1 - 1.3 9.1 4.2 15 5.7 1.4 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KXZ41129.1 - 1.9 7.9 6.1 0.76 9.2 1.4 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF948 PF06103.11 KXZ41129.1 - 3.7 7.9 10.0 7 7.0 2.5 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.8 KXZ41129.1 - 4.7 6.3 13.6 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein MCU PF04678.13 KXZ41129.1 - 5.4 7.1 5.9 23 5.0 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CENP-H PF05837.12 KXZ41129.1 - 7.4 7.0 15.5 3.5 8.1 6.0 3.1 3 1 1 4 4 3 0 Centromere protein H (CENP-H) DUF4893 PF16233.5 KXZ41129.1 - 7.9 6.0 10.7 4.6 6.8 4.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4893) Ank_2 PF12796.7 KXZ41131.1 - 1e-11 45.2 0.0 7.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41131.1 - 7.3e-10 39.2 0.0 0.0019 18.7 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41131.1 - 8e-07 28.9 0.1 0.89 10.3 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXZ41131.1 - 0.00065 20.0 0.1 0.27 11.6 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) F-box PF00646.33 KXZ41131.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain Spt5_N PF11942.8 KXZ41135.1 - 8.2 7.5 14.4 1.1 10.3 9.6 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal COPI_C PF06957.11 KXZ41135.1 - 9.9 4.8 9.0 11 4.6 9.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF4287 PF14117.6 KXZ41136.1 - 0.06 13.5 0.0 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Z1 PF10593.9 KXZ41137.1 - 0.003 17.1 0.0 0.0053 16.3 0.0 1.4 1 1 0 1 1 1 1 Z1 domain SlyX PF04102.12 KXZ41137.1 - 0.0068 17.0 3.8 0.036 14.7 3.8 2.2 1 1 0 1 1 1 1 SlyX DUF2508 PF10704.9 KXZ41137.1 - 0.26 11.5 4.6 9 6.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DUF4404 PF14357.6 KXZ41137.1 - 3.5 8.3 8.9 15 6.3 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) TetR_C_22 PF17928.1 KXZ41138.1 - 0.097 13.0 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-RING_2 PF13639.6 KXZ41139.1 - 6.5e-10 39.2 10.6 9.1e-10 38.7 10.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXZ41139.1 - 1.9e-07 30.7 3.7 1.9e-07 30.7 3.7 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXZ41139.1 - 3.2e-07 30.1 10.3 4.7e-07 29.5 10.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ41139.1 - 1.4e-06 28.4 7.3 2.8e-06 27.5 7.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXZ41139.1 - 3e-05 23.8 9.5 4.3e-05 23.3 9.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ41139.1 - 0.0001 22.2 3.4 0.0001 22.2 3.4 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ41139.1 - 0.0031 17.5 9.2 0.0044 17.0 9.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXZ41139.1 - 0.0034 17.4 2.5 0.0057 16.7 2.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXZ41139.1 - 0.0035 17.2 8.2 0.0054 16.6 8.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 KXZ41139.1 - 0.021 14.7 0.9 0.041 13.7 0.9 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Acyl-CoA_dh_N PF02771.16 KXZ41139.1 - 0.023 15.4 0.9 0.023 15.4 0.9 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Prok-RING_4 PF14447.6 KXZ41139.1 - 0.084 12.8 9.6 0.13 12.2 9.6 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXZ41139.1 - 0.96 9.1 8.7 1.6 8.4 8.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type NLE PF08154.12 KXZ41140.1 - 1e-13 51.6 0.1 1.5e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KXZ41140.1 - 3.4e-10 40.3 0.2 7.6e-10 39.2 0.2 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXZ41140.1 - 0.00014 20.9 0.0 0.00017 20.6 0.0 1.1 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KXZ41140.1 - 0.014 15.7 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KXZ41141.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.20 KXZ41142.1 - 1e-07 31.9 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HC2 PF07382.11 KXZ41146.1 - 0.00071 19.7 5.2 0.001 19.2 5.2 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Nop53 PF07767.11 KXZ41146.1 - 0.13 11.6 9.7 0.15 11.4 9.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FUSC PF04632.12 KXZ41146.1 - 3.4 6.1 13.3 3.6 6.0 13.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Flavodoxin_1 PF00258.25 KXZ41147.1 - 2.7e-35 121.7 0.0 1.1e-24 87.2 0.0 2.0 1 1 1 2 2 2 2 Flavodoxin Helicase_C PF00271.31 KXZ41148.1 - 6e-27 94.2 0.0 1.7e-26 92.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ41148.1 - 5.4e-25 88.2 0.0 1.1e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Tropomyosin_1 PF12718.7 KXZ41149.1 - 0.021 15.0 8.0 0.17 12.0 8.6 2.0 2 0 0 2 2 2 0 Tropomyosin like CENP-Q PF13094.6 KXZ41149.1 - 0.021 15.0 6.6 0.047 13.9 6.6 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit UPF0242 PF06785.11 KXZ41149.1 - 0.07 13.2 4.0 0.12 12.5 4.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 KXZ41149.1 - 0.37 10.9 20.4 0.8 9.8 20.4 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.11 KXZ41149.1 - 1.1 9.1 7.5 2.3 8.0 7.5 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 Caskin-tail PF16632.5 KXZ41149.1 - 2.2 8.7 8.4 0.43 11.0 2.4 2.9 2 1 1 3 3 3 0 C-terminal region of Caskin DUF3103 PF11301.8 KXZ41149.1 - 2.4 6.9 5.9 4 6.1 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Atg14 PF10186.9 KXZ41149.1 - 3.1 6.8 9.1 5.1 6.1 9.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COR PF16095.5 KXZ41150.1 - 2.1e-09 37.5 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain CMS1 PF14617.6 KXZ41150.1 - 0.048 13.0 0.0 0.081 12.2 0.0 1.3 1 1 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1805 PF08827.11 KXZ41150.1 - 0.22 11.9 0.5 1 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) VacA2 PF03077.14 KXZ41151.1 - 0.068 13.0 6.8 0.5 10.2 0.2 2.2 2 0 0 2 2 2 0 Putative vacuolating cytotoxin SR-25 PF10500.9 KXZ41154.1 - 0.041 13.5 16.1 0.079 12.6 16.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_A_type_inc PF04508.12 KXZ41154.1 - 0.16 11.9 1.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PspB PF06667.12 KXZ41154.1 - 3 8.0 9.7 0.19 11.8 0.7 2.4 2 0 0 2 2 2 0 Phage shock protein B LMBR1 PF04791.16 KXZ41154.1 - 4.5 6.1 6.0 5.8 5.7 6.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GREB1 PF15782.5 KXZ41154.1 - 8.3 3.4 8.7 10 3.1 8.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ABC_tran PF00005.27 KXZ41155.1 - 3.6e-05 24.3 0.0 5.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ41155.1 - 0.0088 15.9 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Hint PF01079.20 KXZ41156.1 - 0.00022 20.8 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 Hint module MdcG PF10620.9 KXZ41158.1 - 0.0054 16.5 0.3 0.0091 15.8 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG SET PF00856.28 KXZ41159.1 - 1.3e-09 38.6 0.0 5.2e-09 36.7 0.0 2.0 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KXZ41159.1 - 4.1e-07 30.7 0.0 7.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding PAN_4 PF14295.6 KXZ41161.1 - 9.4e-05 22.2 0.3 0.0004 20.2 0.3 2.1 1 0 0 1 1 1 1 PAN domain EGF PF00008.27 KXZ41161.1 - 0.00043 20.5 4.8 0.045 14.1 0.4 3.6 3 0 0 3 3 3 2 EGF-like domain PAN_1 PF00024.26 KXZ41161.1 - 0.0013 18.7 0.6 0.0013 18.7 0.6 2.5 3 0 0 3 3 3 1 PAN domain EGF_3 PF12947.7 KXZ41161.1 - 0.023 14.9 14.7 0.093 12.9 4.5 3.6 3 0 0 3 3 3 0 EGF domain hEGF PF12661.7 KXZ41161.1 - 0.036 14.7 7.4 0.13 13.0 0.6 3.6 3 0 0 3 3 3 0 Human growth factor-like EGF cEGF PF12662.7 KXZ41161.1 - 0.35 10.8 4.6 1.4 9.0 0.7 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like CBM_14 PF01607.24 KXZ41161.1 - 0.55 10.4 13.7 0.76 10.0 0.3 3.2 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain TACI-CRD2 PF09305.10 KXZ41161.1 - 1.2 9.2 15.1 0.12 12.4 5.0 3.4 3 0 0 3 3 3 0 TACI, cysteine-rich domain DUF4215 PF13948.6 KXZ41161.1 - 1.5 9.3 6.3 16 6.0 2.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4215) Plasmod_Pvs28 PF06247.11 KXZ41161.1 - 7.7 6.9 12.2 7.4 7.0 6.0 3.1 2 0 0 2 2 2 0 Pvs28 EGF domain AAA_11 PF13086.6 KXZ41162.1 - 3.7e-20 72.8 0.0 1.2e-09 38.4 0.2 2.2 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXZ41162.1 - 3.5e-06 26.9 7.1 0.00018 21.3 7.1 3.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ41162.1 - 0.00057 20.2 0.1 0.0046 17.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ41162.1 - 0.0054 17.1 1.1 0.057 13.8 0.1 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXZ41162.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXZ41162.1 - 0.16 11.4 0.0 0.58 9.6 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 KXZ41162.1 - 0.17 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KXZ41162.1 - 0.17 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Phage_Orf51 PF06194.11 KXZ41163.1 - 0.0061 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Phage Conserved Open Reading Frame 51 rve PF00665.26 KXZ41164.1 - 4.5e-16 59.1 0.0 1e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 KXZ41164.1 - 4.8e-16 58.7 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KXZ41164.1 - 1e-09 38.1 0.2 3.1e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.23 KXZ41164.1 - 0.0017 18.3 0.3 0.0017 18.3 0.3 2.0 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.6 KXZ41164.1 - 0.018 14.8 0.0 0.066 13.0 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain DUF4219 PF13961.6 KXZ41164.1 - 0.26 11.0 3.0 0.68 9.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) RVT_2 PF07727.14 KXZ41166.1 - 1e-66 225.0 0.0 1.4e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) mTERF PF02536.14 KXZ41167.1 - 7.7e-06 25.0 0.0 9.9e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 mTERF PP2C PF00481.21 KXZ41169.1 - 1.3e-54 185.6 0.0 9.6e-54 182.7 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXZ41169.1 - 0.00023 20.9 2.6 0.0028 17.3 2.6 2.6 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3228 PF11539.8 KXZ41170.1 - 6.5e-36 123.7 0.0 7.2e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) NUDE_C PF04880.13 KXZ41171.1 - 0.029 14.9 0.1 0.075 13.5 0.0 1.8 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region bZIP_1 PF00170.21 KXZ41171.1 - 0.06 13.4 1.8 0.59 10.3 0.2 2.7 2 1 1 3 3 3 0 bZIP transcription factor Prominin PF05478.11 KXZ41171.1 - 0.063 11.2 0.3 0.086 10.8 0.3 1.1 1 0 0 1 1 1 0 Prominin DivIC PF04977.15 KXZ41171.1 - 0.066 13.0 2.2 0.16 11.8 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 KXZ41171.1 - 0.081 13.3 0.2 0.6 10.6 0.0 2.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) PHM7_cyt PF14703.6 KXZ41171.1 - 0.12 12.7 0.0 0.34 11.1 0.0 1.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Apolipoprotein PF01442.18 KXZ41171.1 - 0.13 12.1 8.7 0.3 10.9 1.6 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain GIT_CC PF16559.5 KXZ41171.1 - 0.17 11.7 0.9 0.45 10.4 0.8 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Mod_r PF07200.13 KXZ41171.1 - 0.31 11.1 3.3 0.15 12.1 1.1 1.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 KXZ41171.1 - 0.4 10.7 7.6 5 7.1 0.8 2.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1690 PF07956.11 KXZ41171.1 - 0.9 10.0 4.4 1.7 9.1 2.0 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Uso1_p115_C PF04871.13 KXZ41171.1 - 4.2 7.8 8.3 14 6.1 1.0 2.8 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 KXZ41171.1 - 5.5 7.1 8.8 1.9 8.6 1.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HisKA_3 PF07730.13 KXZ41171.1 - 7.4 7.2 8.0 11 6.6 0.2 3.4 3 0 0 3 3 3 0 Histidine kinase Pkinase_Tyr PF07714.17 KXZ41174.1 - 5e-34 117.8 0.0 6.8e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ41174.1 - 2.2e-30 105.9 0.0 3.1e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ41174.1 - 0.0013 17.6 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ41174.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ41174.1 - 6 6.7 7.8 1 9.2 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family US2 PF02476.15 KXZ41175.1 - 0.095 13.4 0.0 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 US2 family BCAS2 PF05700.11 KXZ41177.1 - 4.9e-54 183.2 5.5 5.9e-54 182.9 5.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4407 PF14362.6 KXZ41177.1 - 0.036 13.4 0.3 0.052 12.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 KXZ41177.1 - 0.1 11.2 0.5 0.11 11.0 0.5 1.2 1 0 0 1 1 1 0 Macoilin family Paralemmin PF03285.15 KXZ41177.1 - 0.11 12.1 1.0 0.16 11.5 1.0 1.2 1 0 0 1 1 1 0 Paralemmin PD-C2-AF1 PF09310.10 KXZ41179.1 - 0.0012 18.3 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 DUF4799 PF16056.5 KXZ41180.1 - 0.0089 15.2 0.5 0.016 14.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4799) DUF3523 PF12037.8 KXZ41181.1 - 8.8e-20 71.2 5.1 1.1e-19 70.9 5.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) DUF3523 PF12037.8 KXZ41182.1 - 7.1e-16 58.4 0.3 9.6e-16 57.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 KXZ41182.1 - 1.9e-09 38.0 0.1 5.3e-09 36.6 0.0 1.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXZ41182.1 - 5.6e-06 26.2 0.0 8.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXZ41182.1 - 8e-05 22.1 0.1 0.00013 21.4 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ41182.1 - 8.4e-05 23.0 0.0 0.00013 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXZ41182.1 - 0.0013 18.7 0.0 0.003 17.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ41182.1 - 0.0023 18.2 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ41182.1 - 0.0043 17.2 0.1 0.0095 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXZ41182.1 - 0.0052 16.3 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 KXZ41182.1 - 0.0088 16.5 0.1 0.015 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KXZ41182.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KXZ41182.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ41182.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXZ41182.1 - 0.033 14.6 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KXZ41182.1 - 0.039 13.8 0.1 0.083 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KXZ41182.1 - 0.039 13.1 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 KXZ41182.1 - 0.058 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KXZ41182.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain BChl_A PF02327.17 KXZ41182.1 - 0.064 12.1 0.0 1.3 7.7 0.0 2.0 1 1 1 2 2 2 0 Bacteriochlorophyll A protein AAA_18 PF13238.6 KXZ41182.1 - 0.075 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXZ41182.1 - 0.086 12.6 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXZ41182.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Methyltransf_24 PF13578.6 KXZ41183.1 - 1.4e-06 29.3 0.2 8.2e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Gaa1 PF04114.14 KXZ41184.1 - 0.29 10.1 7.8 0.34 9.9 7.8 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component gag-asp_proteas PF13975.6 KXZ41186.1 - 0.0016 18.9 0.0 0.058 14.0 0.0 2.1 1 1 1 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXZ41186.1 - 0.027 15.1 0.0 0.048 14.3 0.0 1.4 1 1 0 1 1 1 0 Aspartyl protease RVP PF00077.20 KXZ41186.1 - 0.11 12.8 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease Y_phosphatase3 PF13350.6 KXZ41187.1 - 0.0027 17.7 0.0 0.0038 17.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXZ41187.1 - 0.0087 15.9 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KXZ41187.1 - 0.023 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KXZ41187.1 - 0.084 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KXZ41187.1 - 0.25 10.9 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pkinase PF00069.25 KXZ41188.1 - 5e-27 94.9 0.0 6.8e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41188.1 - 9.4e-26 90.6 0.0 8.3e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ41188.1 - 0.0044 15.9 0.0 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ41188.1 - 0.0086 16.0 0.2 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ41188.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KXZ41188.1 - 0.27 10.8 0.0 0.43 10.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DHHC PF01529.20 KXZ41189.1 - 1.1e-20 74.1 9.2 2.1e-20 73.2 9.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Cyclin_N PF00134.23 KXZ41190.1 - 4.1e-12 46.0 1.0 2.3e-10 40.3 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KXZ41190.1 - 0.025 14.6 0.1 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KXZ41190.1 - 0.046 14.1 0.3 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain DUF3172 PF11371.8 KXZ41191.1 - 3.2e-55 185.7 0.4 4e-55 185.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) WW PF00397.26 KXZ41193.1 - 2.6e-12 46.6 4.9 2.6e-12 46.6 4.9 1.8 2 0 0 2 2 2 1 WW domain rve PF00665.26 KXZ41194.1 - 5.9e-17 62.0 0.0 2.1e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain PHD PF00628.29 KXZ41194.1 - 2.4e-10 40.1 3.8 2.4e-10 40.1 3.8 2.1 2 0 0 2 2 2 1 PHD-finger zf-ANAPC11 PF12861.7 KXZ41194.1 - 0.013 15.5 3.4 0.04 14.0 3.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger rve_3 PF13683.6 KXZ41194.1 - 0.04 13.7 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain zf-PHD-like PF15446.6 KXZ41194.1 - 0.17 11.5 1.4 0.47 10.1 0.3 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KXZ41194.1 - 0.26 10.9 1.4 0.64 9.6 1.4 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KXZ41194.1 - 0.31 11.4 2.8 0.69 10.3 0.8 2.6 3 0 0 3 3 3 0 RING-like domain zf-rbx1 PF12678.7 KXZ41194.1 - 0.72 10.2 8.0 0.57 10.5 3.6 2.8 3 0 0 3 3 3 0 RING-H2 zinc finger domain Sulfatase PF00884.23 KXZ41196.1 - 3.1e-33 115.5 0.0 4.1e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXZ41196.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KXZ41196.1 - 0.16 12.3 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) RhlB PF12300.8 KXZ41196.1 - 0.67 10.1 13.7 0.45 10.6 12.0 1.5 1 1 0 1 1 1 0 ATP-dependent RNA helicase RhlB DDE_3 PF13358.6 KXZ41197.1 - 1.9e-15 56.9 0.0 2.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 KXZ41197.1 - 0.13 12.5 0.0 0.49 10.6 0.0 1.9 1 1 1 2 2 2 0 Integrase core domain Type_III_YscX PF09474.10 KXZ41198.1 - 0.24 11.7 2.8 0.31 11.3 0.1 2.3 2 1 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) DUF4218 PF13960.6 KXZ41200.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Kinesin PF00225.23 KXZ41202.1 - 1.2e-10 40.9 0.0 7.1e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain LPMO_10 PF03067.15 KXZ41203.1 - 1.4e-12 48.7 0.3 2.1e-12 48.1 0.3 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LysM PF01476.20 KXZ41203.1 - 8.6e-12 44.9 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 LysM domain tRNA-synt_1_2 PF13603.6 KXZ41204.1 - 2.5e-18 66.3 0.0 3.4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 KXZ41204.1 - 1.4e-11 43.4 0.3 5.8e-10 38.1 0.1 3.3 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1 PF00133.22 KXZ41205.1 - 1e-07 30.7 0.0 1.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXZ41205.1 - 5.9e-05 22.0 0.0 7.9e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 KXZ41205.1 - 0.012 14.5 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 KXZ41205.1 - 0.068 12.5 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain WD40 PF00400.32 KXZ41206.1 - 3.7e-67 220.6 32.4 1.9e-10 41.2 1.7 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ41206.1 - 3.5e-33 113.8 3.0 1.7e-06 28.2 0.2 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXZ41206.1 - 4.3e-10 39.3 1.2 0.8 9.7 0.1 5.5 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KXZ41206.1 - 9.3e-07 28.9 0.0 0.059 13.2 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXZ41206.1 - 1.7e-05 23.7 7.0 2.7 6.5 0.1 4.5 2 1 1 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXZ41206.1 - 0.0037 16.3 11.1 0.27 10.1 0.2 5.6 2 2 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KXZ41206.1 - 0.0067 16.1 0.4 70 3.2 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PALB2_WD40 PF16756.5 KXZ41206.1 - 0.083 11.8 6.8 7.6 5.4 0.7 3.9 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DPPIV_N PF00930.21 KXZ41206.1 - 1.5 7.5 5.5 70 2.0 0.1 4.5 3 2 3 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S10 PF00450.22 KXZ41207.1 - 7.6e-98 328.6 0.0 9.9e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase K_channel_TID PF07941.11 KXZ41207.1 - 0.038 14.4 3.2 0.096 13.2 3.2 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CALM_bind PF16025.5 KXZ41207.1 - 0.17 12.3 0.1 0.26 11.8 0.1 1.3 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Amidohydro_3 PF07969.11 KXZ41208.1 - 3.4e-17 63.1 2.4 6e-16 59.0 2.4 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXZ41208.1 - 5.6e-05 22.6 0.0 9.1e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family HYR PF02494.16 KXZ41209.1 - 6.4e-13 48.8 18.4 0.0011 19.2 0.1 5.5 6 0 0 6 6 6 4 HYR domain RicinB_lectin_2 PF14200.6 KXZ41209.1 - 3.8e-05 24.3 0.0 0.00014 22.5 0.0 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like PA14 PF07691.12 KXZ41209.1 - 0.1 12.4 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 PA14 domain EGF_CA PF07645.15 KXZ41209.1 - 0.82 9.9 3.8 3.1 8.1 3.8 2.1 1 0 0 1 1 1 0 Calcium-binding EGF domain DUF2852 PF11014.8 KXZ41209.1 - 1.3 9.2 2.5 2.5 8.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) PAN_4 PF14295.6 KXZ41211.1 - 1.5e-05 24.8 1.5 1.5e-05 24.8 1.5 5.2 3 3 0 3 3 3 1 PAN domain PAN_1 PF00024.26 KXZ41211.1 - 0.00017 21.5 12.1 0.00065 19.6 1.0 2.8 3 0 0 3 3 3 2 PAN domain UvrA_DNA-bind PF17755.1 KXZ41211.1 - 0.089 13.2 0.0 3.1 8.2 0.0 2.3 1 1 1 2 2 2 0 UvrA DNA-binding domain PAN_4 PF14295.6 KXZ41212.1 - 0.55 10.2 4.3 13 5.8 0.2 3.1 2 1 0 2 2 2 0 PAN domain Ribosomal_60s PF00428.19 KXZ41213.1 - 6.4 7.4 11.0 0.057 14.0 2.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein RT_RNaseH_2 PF17919.1 KXZ41214.1 - 1.1e-31 108.8 0.0 2e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ41214.1 - 1.3e-26 92.9 0.2 3.1e-26 91.7 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ41214.1 - 1.5e-18 67.2 0.0 2.5e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KXZ41214.1 - 1.3e-17 63.6 0.0 2.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KXZ41214.1 - 1.7e-08 34.9 0.1 7.4e-08 32.9 0.2 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.26 KXZ41214.1 - 7.4e-06 26.1 0.0 3.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 KXZ41214.1 - 0.0001 22.8 0.3 0.00029 21.4 0.3 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 KXZ41214.1 - 0.00052 20.2 0.0 0.00099 19.3 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 KXZ41214.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease HoxA13_N PF12284.8 KXZ41215.1 - 0.063 13.9 2.3 0.16 12.6 2.3 1.7 1 0 0 1 1 1 0 Hox protein A13 N terminal DUF5506 PF17611.2 KXZ41215.1 - 8.7 6.2 7.4 6.3 6.7 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5506) DUF4215 PF13948.6 KXZ41216.1 - 5.8e-06 26.6 4.3 5.8e-06 26.6 4.3 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4215) PRIMA1 PF16101.5 KXZ41216.1 - 0.37 10.8 5.1 0.73 9.9 5.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Chloroa_b-bind PF00504.21 KXZ41217.1 - 1.9e-51 174.8 0.0 2.4e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 KXZ41218.1 - 4.6e-21 76.0 0.0 5.7e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Helitron_like_N PF14214.6 KXZ41220.1 - 0.00096 19.4 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Dscam_C PF12355.8 KXZ41220.1 - 1.6 9.7 3.4 3.3 8.7 3.4 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Pkinase PF00069.25 KXZ41221.1 - 9.7e-47 159.5 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41221.1 - 8.2e-16 58.1 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.6 KXZ41221.1 - 7.5e-06 25.2 0.0 1.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ41221.1 - 1.4e-05 24.3 0.0 3.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ41221.1 - 0.00011 21.8 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain Kdo PF06293.14 KXZ41221.1 - 0.00029 20.2 0.1 0.00049 19.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ41221.1 - 0.00069 19.0 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like EF-hand_8 PF13833.6 KXZ41221.1 - 0.0042 16.9 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KXZ41221.1 - 0.0095 16.4 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair APH PF01636.23 KXZ41221.1 - 0.11 12.3 0.4 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ41221.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Radical_SAM PF04055.21 KXZ41222.1 - 0.0014 19.0 0.2 0.0031 17.9 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Exostosin PF03016.15 KXZ41223.1 - 1.9e-24 86.4 0.0 6.1e-20 71.6 0.0 2.2 1 1 1 2 2 2 2 Exostosin family EGF_2 PF07974.13 KXZ41223.1 - 0.0036 17.6 30.4 0.04 14.3 17.5 2.8 2 0 0 2 2 2 2 EGF-like domain TPR_2 PF07719.17 KXZ41224.1 - 4.6e-06 26.3 1.0 0.0068 16.4 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ41224.1 - 1.4e-05 24.7 0.9 0.012 15.4 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ41224.1 - 4.2e-05 24.1 0.4 0.00011 22.8 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ41224.1 - 0.011 16.5 0.1 0.047 14.5 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ41224.1 - 0.03 14.3 0.3 13 6.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ41224.1 - 0.031 14.6 0.3 0.055 13.8 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ41224.1 - 0.043 13.7 0.9 0.32 10.9 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ41224.1 - 0.17 12.2 0.2 22 5.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ41224.1 - 0.23 12.2 1.7 1.7 9.5 0.4 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat AAA_30 PF13604.6 KXZ41229.1 - 4.1e-05 23.4 0.0 0.00014 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 KXZ41229.1 - 0.0018 17.5 0.0 0.004 16.4 0.0 1.5 2 0 0 2 2 2 1 PIF1-like helicase AAA_19 PF13245.6 KXZ41229.1 - 0.008 16.5 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Tegument_dsDNA PF12818.7 KXZ41229.1 - 0.0088 15.2 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 dsDNA viral tegument protein PSD1 PF07587.11 KXZ41230.1 - 0.08 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Chloroa_b-bind PF00504.21 KXZ41231.1 - 2.1e-09 38.1 0.6 0.00096 19.7 0.0 2.2 1 1 1 2 2 2 2 Chlorophyll A-B binding protein PRA-PH PF01503.17 KXZ41232.1 - 1.6e-08 34.8 0.0 2.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KXZ41232.1 - 2.2e-05 24.5 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain START PF01852.19 KXZ41232.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 START domain GDPD PF03009.17 KXZ41233.1 - 0.0078 16.0 0.0 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family TFIIA PF03153.13 KXZ41233.1 - 1.6 8.6 38.2 3.2 7.6 38.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 KXZ41233.1 - 3.6 4.6 12.1 5 4.1 12.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 KXZ41233.1 - 8.3 5.1 15.2 12 4.5 15.2 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 KXZ41234.1 - 2.9e-13 49.8 0.0 3.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ41234.1 - 3.3e-08 33.8 0.8 3.7e-06 27.0 0.1 3.0 2 2 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ41234.1 - 0.0078 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ41234.1 - 0.0094 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ41234.1 - 0.0098 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KXZ41234.1 - 0.068 12.7 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF726 PF05277.12 KXZ41235.1 - 1.3e-32 113.1 0.0 1.4e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF1664 PF07889.12 KXZ41238.1 - 0.03 14.4 5.0 0.8 9.8 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MitMem_reg PF13012.6 KXZ41238.1 - 0.053 13.9 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function HrpB7 PF09486.10 KXZ41238.1 - 0.08 13.3 24.3 0.15 12.5 23.1 1.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 KXZ41238.1 - 0.11 12.7 22.0 0.17 12.1 10.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KfrA_N PF11740.8 KXZ41238.1 - 0.12 13.1 0.6 0.12 13.1 0.6 3.1 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term AAA_13 PF13166.6 KXZ41238.1 - 0.17 10.5 8.8 0.23 10.1 8.8 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KXZ41238.1 - 0.25 10.2 19.8 0.082 11.8 11.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein BRE1 PF08647.11 KXZ41238.1 - 0.41 10.8 14.5 0.11 12.6 7.6 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase THOC7 PF05615.13 KXZ41238.1 - 0.49 10.7 19.5 14 5.9 16.7 2.9 1 1 1 2 2 2 0 Tho complex subunit 7 T2SSF PF00482.23 KXZ41238.1 - 0.53 10.2 5.1 1 9.3 5.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F SpecificRecomb PF10136.9 KXZ41238.1 - 0.65 8.2 8.0 0.76 8.0 8.0 1.0 1 0 0 1 1 1 0 Site-specific recombinase Rx_N PF18052.1 KXZ41238.1 - 0.9 9.9 10.1 0.1 12.9 0.9 2.7 1 1 2 3 3 3 0 Rx N-terminal domain DUF2203 PF09969.9 KXZ41238.1 - 0.93 10.2 11.4 2.6 8.8 2.3 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4795 PF16043.5 KXZ41238.1 - 1.2 8.7 16.3 2.5 7.6 3.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Exonuc_VII_L PF02601.15 KXZ41238.1 - 1.3 8.5 12.5 1.6 8.2 12.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 KXZ41238.1 - 1.9 9.0 24.3 1.6 9.3 8.1 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region COG2 PF06148.11 KXZ41238.1 - 1.9 8.6 12.0 0.63 10.1 1.3 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4472 PF14739.6 KXZ41238.1 - 2.2 9.1 16.8 2.7 8.8 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) FAP206 PF12018.8 KXZ41238.1 - 2.9 7.3 9.3 0.47 9.9 5.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF724 PF05266.14 KXZ41238.1 - 3.6 7.4 12.6 3.2 7.5 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Nup88 PF10168.9 KXZ41238.1 - 3.9 5.2 15.4 4.9 4.9 15.4 1.0 1 0 0 1 1 1 0 Nuclear pore component V_ATPase_I PF01496.19 KXZ41238.1 - 7.4 4.3 7.8 4.8 5.0 6.1 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family GAF_2 PF13185.6 KXZ41240.1 - 0.047 14.0 3.0 0.047 14.0 0.1 2.3 2 1 0 2 2 2 0 GAF domain SOG2 PF10428.9 KXZ41240.1 - 2.7 7.1 6.6 3.2 6.9 6.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Smr PF01713.21 KXZ41241.1 - 1.6e-07 31.6 0.0 5.4e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KXZ41241.1 - 2.3e-07 31.1 12.0 7e-07 29.5 12.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Serglycin PF04360.12 KXZ41241.1 - 0.0062 16.5 2.7 0.013 15.4 2.7 1.5 1 0 0 1 1 1 1 Serglycin Period_C PF12114.8 KXZ41241.1 - 0.15 11.6 2.3 0.36 10.4 2.3 1.7 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Cluap1 PF10234.9 KXZ41242.1 - 8e-33 114.0 6.3 9.4e-33 113.7 6.3 1.0 1 0 0 1 1 1 1 Clusterin-associated protein-1 NPV_P10 PF05531.12 KXZ41242.1 - 8e-06 26.2 1.2 1.1e-05 25.7 1.2 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 KXZ41242.1 - 8.8e-05 22.4 5.2 0.00013 21.9 4.7 1.6 1 1 0 1 1 1 1 Prefoldin subunit DASH_Spc19 PF08287.11 KXZ41242.1 - 0.00023 21.1 6.0 0.00023 21.1 6.0 1.4 2 0 0 2 2 1 1 Spc19 DUF4795 PF16043.5 KXZ41242.1 - 0.001 18.7 1.1 0.0011 18.6 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) IFT57 PF10498.9 KXZ41242.1 - 0.0013 17.8 1.9 0.0013 17.8 1.9 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 SKA1 PF07160.12 KXZ41242.1 - 0.0016 18.3 0.4 0.0018 18.2 0.4 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 TMF_DNA_bd PF12329.8 KXZ41242.1 - 0.0018 18.3 6.0 0.0029 17.6 6.0 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Not3 PF04065.15 KXZ41242.1 - 0.0028 17.1 1.5 0.0031 17.0 1.5 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Prefoldin PF02996.17 KXZ41242.1 - 0.0035 17.2 6.2 0.017 15.0 5.8 1.9 1 1 1 2 2 2 1 Prefoldin subunit ADIP PF11559.8 KXZ41242.1 - 0.0049 17.0 3.5 0.0055 16.8 3.5 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF5403 PF17395.2 KXZ41242.1 - 0.0059 16.9 1.4 0.041 14.2 0.6 2.2 1 1 0 2 2 2 1 Family of unknown function (DUF5403) DUF16 PF01519.16 KXZ41242.1 - 0.0063 17.0 1.9 0.007 16.8 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 DUF3450 PF11932.8 KXZ41242.1 - 0.0074 15.6 3.3 0.0081 15.5 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Herpes_UL6 PF01763.16 KXZ41242.1 - 0.0079 14.8 0.8 0.0084 14.7 0.8 1.0 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF812 PF05667.11 KXZ41242.1 - 0.0081 15.1 3.9 0.0084 15.0 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 KXZ41242.1 - 0.0099 14.8 6.3 0.013 14.4 6.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Cas_Csa4 PF09703.10 KXZ41242.1 - 0.01 15.2 0.3 0.011 15.1 0.3 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csa4) CREPT PF16566.5 KXZ41242.1 - 0.01 16.0 3.0 0.012 15.8 3.0 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Lebercilin PF15619.6 KXZ41242.1 - 0.015 15.0 8.7 0.022 14.5 8.7 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease YlqD PF11068.8 KXZ41242.1 - 0.015 15.6 3.3 0.022 15.1 3.3 1.3 1 0 0 1 1 1 0 YlqD protein HemX PF04375.14 KXZ41242.1 - 0.016 14.5 1.5 0.017 14.5 1.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Ax_dynein_light PF10211.9 KXZ41242.1 - 0.02 14.8 5.8 0.027 14.4 5.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Nup88 PF10168.9 KXZ41242.1 - 0.023 12.5 1.0 0.027 12.3 1.0 1.0 1 0 0 1 1 1 0 Nuclear pore component FliD_C PF07195.12 KXZ41242.1 - 0.023 14.1 0.7 0.029 13.8 0.7 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FapA PF03961.13 KXZ41242.1 - 0.026 13.2 1.9 0.027 13.1 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KXZ41242.1 - 0.029 14.5 5.1 0.032 14.3 5.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2524 PF10732.9 KXZ41242.1 - 0.029 14.6 6.8 0.042 14.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) DUF3847 PF12958.7 KXZ41242.1 - 0.029 14.5 9.2 0.73 10.0 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) TMPIT PF07851.13 KXZ41242.1 - 0.03 13.6 2.3 0.037 13.3 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Lectin_N PF03954.14 KXZ41242.1 - 0.031 14.0 0.3 0.042 13.6 0.3 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain HlyD_2 PF12700.7 KXZ41242.1 - 0.032 13.0 2.0 0.036 12.8 2.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein FlxA PF14282.6 KXZ41242.1 - 0.04 13.9 4.0 0.058 13.4 4.0 1.2 1 0 0 1 1 1 0 FlxA-like protein Occludin_ELL PF07303.13 KXZ41242.1 - 0.045 14.5 4.2 0.089 13.5 4.2 1.4 1 0 0 1 1 1 0 Occludin homology domain AAA_13 PF13166.6 KXZ41242.1 - 0.046 12.4 3.0 0.049 12.3 3.0 1.1 1 0 0 1 1 1 0 AAA domain MPS2 PF17060.5 KXZ41242.1 - 0.05 12.9 1.6 0.054 12.8 1.6 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF1664 PF07889.12 KXZ41242.1 - 0.051 13.6 0.4 0.062 13.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3987 PF13148.6 KXZ41242.1 - 0.054 12.5 1.5 0.069 12.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Exonuc_VII_L PF02601.15 KXZ41242.1 - 0.055 13.0 1.7 0.062 12.9 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 KXZ41242.1 - 0.055 14.0 11.6 0.076 13.6 11.6 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4337 PF14235.6 KXZ41242.1 - 0.058 13.5 2.0 0.061 13.4 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF724 PF05266.14 KXZ41242.1 - 0.063 13.1 3.3 0.07 12.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 KXZ41242.1 - 0.063 13.5 10.7 0.46 10.8 9.2 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain HAUS6_N PF14661.6 KXZ41242.1 - 0.069 12.7 2.1 0.076 12.6 2.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Paralemmin PF03285.15 KXZ41242.1 - 0.069 12.7 4.4 0.083 12.5 4.4 1.1 1 0 0 1 1 1 0 Paralemmin DUF3755 PF12579.8 KXZ41242.1 - 0.071 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) UPF0270 PF06794.12 KXZ41242.1 - 0.079 13.0 1.2 6.9 6.8 0.9 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0270) Golgin_A5 PF09787.9 KXZ41242.1 - 0.085 12.3 6.3 0.095 12.1 6.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 XhlA PF10779.9 KXZ41242.1 - 0.093 12.9 10.2 0.25 11.6 9.4 2.0 1 1 1 2 2 2 0 Haemolysin XhlA Fmp27_WPPW PF10359.9 KXZ41242.1 - 0.095 11.5 2.6 0.11 11.4 2.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DASH_Dam1 PF08653.10 KXZ41242.1 - 0.11 12.4 2.4 0.18 11.6 0.5 2.2 2 1 1 3 3 3 0 DASH complex subunit Dam1 Tup_N PF08581.10 KXZ41242.1 - 0.11 12.8 8.7 0.17 12.2 8.2 1.5 2 0 0 2 2 1 0 Tup N-terminal Fib_alpha PF08702.10 KXZ41242.1 - 0.11 12.6 5.2 0.19 11.9 5.2 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KXZ41242.1 - 0.13 12.6 6.9 0.22 11.8 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) GAS PF13851.6 KXZ41242.1 - 0.13 11.6 9.1 0.18 11.1 9.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FemAB PF02388.16 KXZ41242.1 - 0.14 11.0 2.4 0.17 10.7 2.4 1.1 1 0 0 1 1 1 0 FemAB family Atg14 PF10186.9 KXZ41242.1 - 0.16 11.0 2.5 0.17 10.9 2.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KXZ41242.1 - 0.17 11.2 2.3 0.19 11.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) STAT_alpha PF01017.20 KXZ41242.1 - 0.17 11.8 5.5 0.24 11.3 5.5 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain BRI3BP PF14965.6 KXZ41242.1 - 0.2 11.2 0.1 0.2 11.2 0.1 1.4 2 0 0 2 2 1 0 Negative regulator of p53/TP53 YabA PF06156.13 KXZ41242.1 - 0.23 12.1 4.2 0.36 11.5 4.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Med9 PF07544.13 KXZ41242.1 - 0.24 11.5 7.9 0.66 10.1 7.9 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FliJ PF02050.16 KXZ41242.1 - 0.24 11.6 9.7 1.2 9.4 2.8 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein MotA_ExbB PF01618.16 KXZ41242.1 - 0.25 11.1 1.0 0.58 9.9 1.0 1.7 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF919 PF06034.11 KXZ41242.1 - 0.46 10.3 7.9 0.73 9.7 6.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) V_ATPase_I PF01496.19 KXZ41242.1 - 0.6 8.0 1.8 0.62 7.9 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family E2F_CC-MB PF16421.5 KXZ41242.1 - 0.67 10.4 5.7 0.92 9.9 5.3 1.4 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain ORF6C PF10552.9 KXZ41242.1 - 1.1 9.4 6.4 6.4 6.9 1.6 2.1 1 1 1 2 2 2 0 ORF6C domain DivIC PF04977.15 KXZ41242.1 - 1.6 8.6 10.1 23 4.8 10.1 2.3 1 1 0 1 1 1 0 Septum formation initiator Spc24 PF08286.11 KXZ41242.1 - 2.4 8.4 7.8 4.9 7.4 7.8 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CENP-Q PF13094.6 KXZ41242.1 - 2.8 8.1 13.6 0.79 9.9 10.7 1.6 2 1 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 PF13600.6 KXZ41242.1 - 3.2 8.3 8.4 28 5.2 8.4 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SelK_SelG PF10961.8 KXZ41244.1 - 5.2e-16 59.0 0.8 6e-16 58.8 0.8 1.1 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Glyco_transf_90 PF05686.12 KXZ41246.1 - 1.7e-38 132.6 0.0 1e-28 100.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXZ41246.1 - 0.0023 18.3 0.1 0.0053 17.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 BACK PF07707.15 KXZ41249.1 - 6.4e-06 26.2 0.1 1.4e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ41249.1 - 0.00047 20.4 0.0 0.001 19.3 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Acetyltransf_1 PF00583.25 KXZ41251.1 - 4.9e-12 46.1 0.0 1e-11 45.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ41251.1 - 2.3e-10 40.7 0.0 1.4e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ41251.1 - 2.4e-06 27.5 0.0 5.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ41251.1 - 0.00056 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXZ41251.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KXZ41251.1 - 0.0099 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KXZ41251.1 - 0.12 12.5 0.0 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KXZ41251.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase C2 PF00168.30 KXZ41254.1 - 0.11 12.8 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 C2 domain Chloroa_b-bind PF00504.21 KXZ41255.1 - 8.3e-51 172.7 0.1 1e-50 172.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RT_RNaseH_2 PF17919.1 KXZ41257.1 - 4.4e-14 52.3 0.0 8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ41257.1 - 2.6e-07 30.8 0.0 4.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase EcKinase PF02958.20 KXZ41258.1 - 3.3e-05 23.4 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KXZ41258.1 - 0.00037 20.5 0.6 0.00037 20.5 0.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ41258.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cwf_Cwc_15 PF04889.12 KXZ41259.1 - 0.078 12.7 11.5 0.13 12.0 11.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KXZ41259.1 - 0.12 11.8 13.4 0.16 11.3 13.4 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXZ41259.1 - 0.19 9.9 12.0 0.24 9.6 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 KXZ41259.1 - 0.49 9.1 2.3 0.84 8.3 2.3 1.3 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.11 KXZ41259.1 - 1.7 8.0 14.9 2.6 7.3 14.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SNAP PF14938.6 KXZ41260.1 - 1e-92 310.5 15.3 1.2e-92 310.4 15.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KXZ41260.1 - 5.9e-05 23.3 16.9 0.029 14.7 4.2 4.1 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ41260.1 - 0.00055 20.5 16.1 0.3 12.0 0.1 5.4 3 1 2 5 5 5 2 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KXZ41260.1 - 0.00095 18.8 3.3 0.06 12.9 0.9 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 TPR_6 PF13174.6 KXZ41260.1 - 0.0026 18.3 13.3 3 8.7 0.1 5.5 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ41260.1 - 0.0041 17.7 15.7 1.5 9.6 0.2 4.5 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ41260.1 - 0.011 15.9 19.6 1.3 9.4 1.1 5.7 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ41260.1 - 0.012 15.0 3.7 0.049 13.0 1.0 2.6 1 1 0 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 KXZ41260.1 - 0.015 15.3 13.8 0.52 10.5 0.0 5.1 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ41260.1 - 0.02 15.0 2.4 0.02 15.0 2.4 5.7 4 1 3 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 KXZ41260.1 - 0.022 14.8 3.0 0.022 14.8 3.0 4.4 3 2 1 4 4 4 0 MIT (microtubule interacting and transport) domain PPR_2 PF13041.6 KXZ41260.1 - 0.092 12.9 3.3 9.3 6.5 0.0 3.4 4 0 0 4 4 3 0 PPR repeat family PT-VENN PF04829.13 KXZ41260.1 - 0.13 12.4 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif RPN7 PF10602.9 KXZ41260.1 - 0.26 11.0 11.9 31 4.2 11.8 3.1 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Spatacsin_C PF14649.6 KXZ41260.1 - 0.38 9.8 8.1 2.1 7.4 8.1 2.0 1 1 0 1 1 1 0 Spatacsin C-terminus ANAPC3 PF12895.7 KXZ41260.1 - 0.69 10.2 9.9 2.6 8.3 0.4 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXZ41260.1 - 0.73 9.8 15.4 2.8 7.9 0.1 5.2 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ41260.1 - 1.1 9.2 21.7 0.19 11.6 2.0 5.1 3 2 3 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 KXZ41260.1 - 4.9 8.0 11.9 20 6.0 0.5 4.4 3 1 0 3 3 3 0 Sel1 repeat Chlam_PMP PF02415.17 KXZ41261.1 - 0.00058 20.2 65.1 0.033 14.7 1.2 9.0 9 1 0 9 9 9 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Phage_integrase PF00589.22 KXZ41262.1 - 0.00033 20.5 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Cwf_Cwc_15 PF04889.12 KXZ41263.1 - 0.034 13.9 11.4 0.059 13.1 11.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4692 PF15763.5 KXZ41263.1 - 0.078 13.4 5.6 0.15 12.6 5.6 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Apt1 PF10351.9 KXZ41263.1 - 0.11 11.3 5.0 0.12 11.2 5.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FancD2 PF14631.6 KXZ41263.1 - 0.18 9.2 8.3 0.24 8.8 8.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF755 PF05501.11 KXZ41263.1 - 0.26 11.6 17.2 0.55 10.5 17.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TFIIA PF03153.13 KXZ41263.1 - 0.28 11.1 12.6 0.48 10.4 12.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 KXZ41263.1 - 0.41 9.4 2.6 0.43 9.3 2.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 KXZ41263.1 - 0.97 8.8 7.6 0.36 10.2 5.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DNA_pol_phi PF04931.13 KXZ41263.1 - 0.97 7.5 9.0 1.4 7.0 9.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi NPR3 PF03666.13 KXZ41263.1 - 1 8.1 7.7 1.4 7.6 7.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 KXZ41263.1 - 1.4 7.0 3.4 1.3 7.0 3.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 KXZ41263.1 - 2.2 5.3 7.7 2.6 5.1 7.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1754 PF08555.10 KXZ41263.1 - 3.4 8.5 21.3 0.71 10.7 17.0 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Ndc1_Nup PF09531.10 KXZ41263.1 - 5.2 5.6 6.1 5.8 5.5 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM176 PF14851.6 KXZ41263.1 - 8.9 6.0 6.2 17 5.1 6.2 1.4 1 0 0 1 1 1 0 FAM176 family TRP PF06011.12 KXZ41264.1 - 9.3e-07 27.9 12.7 2.1e-06 26.7 12.7 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Keratin_B2 PF01500.17 KXZ41266.1 - 0.74 9.8 6.7 0.25 11.3 2.7 2.0 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein DUF3707 PF12499.8 KXZ41267.1 - 9.4e-35 120.3 10.0 5.4e-25 88.6 3.6 2.4 2 0 0 2 2 2 2 Pherophorin Ank_3 PF13606.6 KXZ41268.1 - 3.6e-05 23.8 0.2 0.76 10.5 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KXZ41268.1 - 6.3e-05 23.4 0.0 0.0018 18.8 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ41268.1 - 0.00011 22.7 0.0 0.0043 17.6 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) His_Phos_1 PF00300.22 KXZ41269.1 - 7.2e-14 51.9 0.0 5.5e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PIG-L PF02585.17 KXZ41270.1 - 0.17 12.5 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase WD40 PF00400.32 KXZ41271.1 - 7e-15 55.2 0.1 1.1e-05 26.0 0.2 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ41271.1 - 6.3e-08 32.8 0.0 0.013 15.8 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ41271.1 - 0.068 12.1 0.1 0.13 11.2 0.0 1.6 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cu-oxidase_3 PF07732.15 KXZ41271.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Multicopper oxidase eIF2A PF08662.11 KXZ41271.1 - 0.18 11.7 0.0 0.56 10.1 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A CENP-T_C PF15511.6 KXZ41272.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ41272.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ41272.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ41272.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ41272.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ41272.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ41272.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated CAP_N PF01213.19 KXZ41273.1 - 0.71 9.3 3.1 1.1 8.7 3.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IFP_35_N PF07334.13 KXZ41276.1 - 0.0073 16.4 1.0 0.0089 16.1 1.0 1.1 1 0 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus HTH_20 PF12840.7 KXZ41276.1 - 0.017 15.2 0.3 0.04 14.0 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3287 PF11690.8 KXZ41276.1 - 0.049 13.4 0.4 0.054 13.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Lustrin_cystein PF14625.6 KXZ41277.1 - 2 8.8 21.7 1.8 9.0 0.9 4.2 3 1 1 4 4 4 0 Lustrin, cysteine-rich repeated domain Thioredoxin PF00085.20 KXZ41278.1 - 8.7e-13 48.1 0.0 9.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ41278.1 - 4.3e-06 27.2 0.1 0.00018 21.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ41278.1 - 5.4e-05 23.4 0.0 0.099 13.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Glutaredoxin PF00462.24 KXZ41278.1 - 0.0013 18.9 0.1 0.0027 17.9 0.1 1.6 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KXZ41278.1 - 0.014 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain OST3_OST6 PF04756.13 KXZ41278.1 - 0.06 12.7 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family KaiB PF07689.12 KXZ41278.1 - 0.067 12.9 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 KaiB domain DUF836 PF05768.14 KXZ41278.1 - 0.11 12.9 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.21 KXZ41278.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family ECR1_N PF14382.6 KXZ41279.1 - 3e-08 33.3 0.4 6.6e-08 32.2 0.4 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region pPIWI_RE_REase PF18154.1 KXZ41279.1 - 0.087 12.8 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 REase associating with pPIWI_RE EXOSC1 PF10447.9 KXZ41279.1 - 0.095 13.3 0.1 3.4 8.3 0.1 2.3 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 DUF3537 PF12056.8 KXZ41280.1 - 0.0033 16.3 0.3 0.0076 15.1 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3537) TRP PF06011.12 KXZ41282.1 - 0.0028 16.5 10.0 0.011 14.5 10.0 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF2614 PF11023.8 KXZ41282.1 - 6.9 6.8 6.9 3.3 7.8 3.1 2.4 2 1 1 3 3 3 0 Zinc-ribbon containing domain RWP-RK PF02042.15 KXZ41283.1 - 4.7e-13 48.9 0.0 8.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_AraC PF00165.23 KXZ41283.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Herpes_UL32 PF06070.11 KXZ41285.1 - 0.026 12.3 1.7 0.038 11.7 1.7 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 CCDC23 PF15674.5 KXZ41285.1 - 0.22 11.5 12.5 0.71 9.9 12.6 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 23 Ribosomal_60s PF00428.19 KXZ41286.1 - 3.2e-27 94.9 7.6 3.7e-27 94.7 7.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4641 PF15483.6 KXZ41286.1 - 0.14 11.2 1.7 0.17 11.0 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) Prenyltransf PF01255.19 KXZ41287.1 - 5.8e-74 248.4 0.0 6.7e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PRC PF05239.16 KXZ41288.1 - 1.8e-12 47.2 0.1 2.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 PRC-barrel domain GYF PF02213.16 KXZ41289.1 - 0.00014 21.5 0.4 0.0002 20.9 0.4 1.3 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXZ41289.1 - 0.0029 17.4 1.7 0.0031 17.3 0.2 1.8 2 0 0 2 2 2 1 GYF domain 2 YCII PF03795.14 KXZ41290.1 - 2.6e-09 37.4 0.0 3.2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF2374 PF09574.10 KXZ41291.1 - 0.71 9.7 11.2 0.3 11.0 2.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Collagen PF01391.18 KXZ41293.1 - 0.17 11.6 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Coq4 PF05019.13 KXZ41294.1 - 1.1e-83 280.0 0.0 1.2e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Clathrin_lg_ch PF01086.17 KXZ41295.1 - 4.2e-21 76.1 0.0 4.8e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Clathrin light chain B277 PF17623.2 KXZ41295.1 - 0.023 13.8 2.5 0.032 13.3 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function LPP PF04728.13 KXZ41296.1 - 0.0066 16.8 1.5 0.39 11.1 0.1 2.2 1 1 1 2 2 2 1 Lipoprotein leucine-zipper GAS PF13851.6 KXZ41296.1 - 0.015 14.6 0.5 0.017 14.5 0.5 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Uds1 PF15456.6 KXZ41296.1 - 0.026 14.7 1.2 0.1 12.7 1.3 1.7 1 1 0 1 1 1 0 Up-regulated During Septation Paralemmin PF03285.15 KXZ41296.1 - 0.027 14.1 0.4 0.029 14.0 0.4 1.1 1 0 0 1 1 1 0 Paralemmin APG17 PF04108.12 KXZ41296.1 - 0.03 13.4 0.0 0.033 13.3 0.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 HALZ PF02183.18 KXZ41296.1 - 0.034 14.4 1.1 5.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper BLOC1_2 PF10046.9 KXZ41296.1 - 0.037 14.3 0.6 0.069 13.5 0.6 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 KXZ41296.1 - 0.037 14.1 0.9 0.14 12.2 0.8 1.9 1 1 0 1 1 1 0 bZIP transcription factor BRE1 PF08647.11 KXZ41296.1 - 0.038 14.0 0.4 0.052 13.6 0.4 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase LURAP PF14854.6 KXZ41296.1 - 0.044 13.7 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 Leucine rich adaptor protein Phage_GP20 PF06810.11 KXZ41296.1 - 0.047 13.5 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 MbeD_MobD PF04899.12 KXZ41296.1 - 0.072 13.2 3.9 0.57 10.3 0.8 2.1 1 1 1 2 2 2 0 MbeD/MobD like RPN7 PF10602.9 KXZ41296.1 - 0.074 12.8 0.2 0.08 12.6 0.2 1.1 1 0 0 1 1 1 0 26S proteasome subunit RPN7 bZIP_2 PF07716.15 KXZ41296.1 - 0.078 13.1 2.5 0.21 11.7 0.9 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Pox_Ag35 PF03286.14 KXZ41296.1 - 0.081 12.7 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TMF_DNA_bd PF12329.8 KXZ41296.1 - 0.081 12.9 0.7 0.17 11.9 0.8 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Not3 PF04065.15 KXZ41296.1 - 0.094 12.1 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DASH_Dam1 PF08653.10 KXZ41296.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 DASH complex subunit Dam1 CLZ PF16526.5 KXZ41296.1 - 0.1 12.9 1.1 0.3 11.5 0.9 1.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 KXZ41296.1 - 0.12 13.0 0.1 0.15 12.7 0.1 1.2 1 0 0 1 1 1 0 Initiation control protein YabA FlaC_arch PF05377.11 KXZ41296.1 - 0.13 12.7 0.1 0.86 10.0 0.1 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 KXZ41296.1 - 0.25 11.3 2.2 1.2 9.1 0.4 1.9 1 1 1 2 2 2 0 FlxA-like protein Osmo_CC PF08946.10 KXZ41296.1 - 0.27 11.5 1.7 2.1 8.6 0.6 2.2 1 1 1 2 2 2 0 Osmosensory transporter coiled coil DUF2304 PF10066.9 KXZ41296.1 - 0.39 11.0 1.4 1.6 9.0 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) zf-3CxxC_2 PF17180.4 KXZ41297.1 - 8.9e-09 36.0 1.4 1.4e-08 35.3 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding domain Zn_clus PF00172.18 KXZ41297.1 - 0.0074 16.4 3.6 0.012 15.7 0.1 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-3CxxC PF13695.6 KXZ41297.1 - 0.11 13.0 3.3 0.24 11.9 3.3 1.6 1 1 0 1 1 1 0 Zinc-binding domain Pkinase PF00069.25 KXZ41298.1 - 3.3e-11 43.1 0.0 5.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ41298.1 - 3e-05 24.1 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ41298.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ41298.1 - 0.045 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ41298.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ALAD PF00490.21 KXZ41299.1 - 1.1e-129 432.2 0.0 1.3e-129 432.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MOFRL PF05161.13 KXZ41299.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 MOFRL family Sucrose_synth PF00862.19 KXZ41299.1 - 0.22 9.8 0.1 0.44 8.8 0.0 1.4 2 0 0 2 2 2 0 Sucrose synthase Ribosomal_L15e PF00827.17 KXZ41300.1 - 7.1e-92 306.4 8.4 8.2e-92 306.2 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 CDP-OH_P_transf PF01066.21 KXZ41301.1 - 5.9e-12 46.2 0.7 5.9e-12 46.2 0.7 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cluap1 PF10234.9 KXZ41302.1 - 3.7e-24 85.6 10.8 3.7e-24 85.6 10.8 1.7 1 1 1 2 2 2 1 Clusterin-associated protein-1 YxiJ PF14176.6 KXZ41302.1 - 0.0091 16.5 2.5 0.015 15.8 2.4 1.6 1 1 0 1 1 1 1 YxiJ-like protein HrpB7 PF09486.10 KXZ41302.1 - 0.021 15.2 2.1 0.027 14.9 2.1 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 KXZ41302.1 - 0.029 15.0 3.3 0.42 11.3 0.1 2.3 2 0 0 2 2 2 0 SlyX DUF745 PF05335.13 KXZ41302.1 - 0.068 12.9 4.9 0.082 12.6 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Golgin_A5 PF09787.9 KXZ41302.1 - 0.071 12.6 8.7 0.084 12.3 8.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3918 PF13056.6 KXZ41302.1 - 0.088 12.4 0.7 0.19 11.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) KxDL PF10241.9 KXZ41302.1 - 0.31 11.3 9.0 0.052 13.8 1.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.15 KXZ41302.1 - 0.35 10.4 6.0 0.4 10.2 6.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FadA PF09403.10 KXZ41302.1 - 0.65 10.5 15.1 5.1 7.6 14.9 1.9 1 1 0 1 1 1 0 Adhesion protein FadA FapA PF03961.13 KXZ41302.1 - 0.7 8.4 7.0 0.89 8.1 7.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A XhlA PF10779.9 KXZ41302.1 - 1.5 9.1 8.9 3 8.1 0.2 2.7 2 1 1 3 3 3 0 Haemolysin XhlA IFT57 PF10498.9 KXZ41302.1 - 2 7.3 12.1 45 2.9 12.1 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 KXZ41302.1 - 3.6 7.8 8.6 6.7 6.9 8.6 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 KXZ41302.1 - 7 6.7 17.8 0.52 10.4 7.1 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IFT20 PF14931.6 KXZ41302.1 - 7.8 6.7 12.7 1.3 9.2 5.6 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 OmpH PF03938.14 KXZ41302.1 - 9.4 6.6 17.6 62 3.9 17.5 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_60s PF00428.19 KXZ41303.1 - 0.14 12.8 14.5 7 7.3 0.1 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Cwf_Cwc_15 PF04889.12 KXZ41304.1 - 0.025 14.3 1.0 0.03 14.1 1.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 KXZ41304.1 - 0.044 14.0 8.7 0.057 13.7 8.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Prothymosin PF03247.14 KXZ41304.1 - 0.11 12.9 19.0 0.17 12.3 19.0 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nop14 PF04147.12 KXZ41304.1 - 0.25 9.5 6.2 0.26 9.4 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 KXZ41304.1 - 1.5 7.7 9.8 1.8 7.5 9.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4746 PF15928.5 KXZ41304.1 - 2.2 7.6 5.5 2.8 7.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 KXZ41304.1 - 3.2 5.7 14.4 4 5.4 14.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KXZ41304.1 - 3.6 6.8 8.0 4.4 6.6 8.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 KXZ41304.1 - 6.8 6.4 9.1 12 5.6 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Herpes_UL73 PF03554.13 KXZ41305.1 - 0.067 13.2 1.1 0.13 12.3 1.1 1.4 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein SelK_SelG PF10961.8 KXZ41305.1 - 0.54 10.9 6.4 0.22 12.2 2.1 2.3 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Phage_holin_5_1 PF06946.11 KXZ41305.1 - 8.5 6.8 9.3 0.4 11.1 0.4 2.5 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 F-box PF00646.33 KXZ41307.1 - 0.029 14.3 1.3 4.4 7.3 0.2 2.9 2 0 0 2 2 2 0 F-box domain Serendipity_A PF05482.12 KXZ41307.1 - 0.15 10.7 0.0 6.6 5.2 0.0 2.0 2 0 0 2 2 2 0 Serendipity locus alpha protein (SRY-A) Ank_2 PF12796.7 KXZ41310.1 - 6e-11 42.8 0.5 0.00027 21.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41310.1 - 3.5e-10 40.2 0.1 4.5e-06 27.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41310.1 - 3.9e-10 39.1 0.1 0.00069 19.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat zf-C3HC4_3 PF13920.6 KXZ41310.1 - 2.1e-08 33.9 6.3 3e-08 33.4 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 KXZ41310.1 - 3.7e-07 30.3 0.8 0.021 15.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41310.1 - 6.8e-07 29.5 1.3 0.02 15.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 KXZ41310.1 - 0.34 11.3 6.2 0.62 10.4 6.2 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KXZ41310.1 - 1.4 8.8 7.0 2.5 8.0 7.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Dicer_dimer PF03368.14 KXZ41313.1 - 3.3e-05 23.9 0.0 8.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain DND1_DSRM PF14709.7 KXZ41313.1 - 3.7e-05 23.9 0.3 0.00013 22.1 0.3 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KXZ41313.1 - 0.0045 17.7 0.0 0.012 16.3 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif DctQ PF04290.12 KXZ41314.1 - 0.029 14.3 0.5 0.029 14.3 0.5 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component RNA_helicase PF00910.22 KXZ41316.1 - 0.098 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RNase_HII PF01351.18 KXZ41316.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease HII Pkinase PF00069.25 KXZ41317.1 - 6.3e-22 78.2 0.0 8.3e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41317.1 - 7.2e-19 68.1 0.0 8.7e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ41317.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ41317.1 - 0.037 14.0 0.5 0.072 13.0 0.1 1.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family ClpS PF02617.17 KXZ41318.1 - 1.8e-17 62.8 0.3 2.3e-17 62.5 0.3 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS AbLIM_anchor PF16182.5 KXZ41318.1 - 0.065 13.1 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM TRIC PF05197.13 KXZ41319.1 - 3.6e-12 46.3 0.8 4.4e-12 46.0 0.8 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 KXZ41319.1 - 0.16 11.9 6.1 0.31 10.9 0.8 2.6 2 0 0 2 2 2 0 UPF0126 domain Hint PF01079.20 KXZ41320.1 - 4.6e-13 49.2 0.0 3.2e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Hint module DUF347 PF03988.12 KXZ41320.1 - 2.5 8.3 4.9 4.1 7.7 1.0 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) COX7a PF02238.15 KXZ41320.1 - 5.8 7.4 10.3 34 4.9 0.1 3.7 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VII DUF3439 PF11921.8 KXZ41321.1 - 1.5 8.8 13.2 3.2 7.8 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RT_RNaseH_2 PF17919.1 KXZ41322.1 - 2e-33 114.4 0.0 3.1e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ41322.1 - 2.4e-30 104.9 0.1 3.8e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Aminotran_5 PF00266.19 KXZ41323.1 - 1.6e-32 112.9 0.0 2e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ank_4 PF13637.6 KXZ41324.1 - 0.015 15.9 0.4 8.9 7.0 0.0 3.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Histone PF00125.24 KXZ41326.1 - 1.7e-41 141.7 2.0 1.8e-41 141.5 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ41326.1 - 5.2e-05 23.5 0.0 6.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ41326.1 - 0.00016 21.8 0.1 0.00018 21.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ41326.1 - 0.0019 18.4 0.1 0.0027 18.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ41326.1 - 0.0041 17.2 0.0 0.0053 16.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CCDC24 PF15669.5 KXZ41327.1 - 1.5e-48 165.3 0.3 1.5e-48 165.3 0.3 4.2 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 24 family PrmA PF06325.13 KXZ41329.1 - 4.3e-68 229.9 0.0 6.2e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXZ41329.1 - 1.8e-06 27.8 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ41329.1 - 7.4e-05 22.7 0.0 0.00018 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ41329.1 - 0.00011 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXZ41329.1 - 0.00012 22.7 0.0 0.0019 18.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ41329.1 - 0.0056 17.3 0.4 0.1 13.3 0.4 2.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KXZ41329.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SBP PF03110.14 KXZ41330.1 - 1.7e-23 82.7 1.7 2.2e-23 82.3 1.7 1.1 1 0 0 1 1 1 1 SBP domain Pkinase PF00069.25 KXZ41331.1 - 1.1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41331.1 - 1.8e-07 30.7 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ41331.1 - 0.029 14.3 0.1 0.029 14.3 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ank_4 PF13637.6 KXZ41332.1 - 3.4e-08 33.9 0.1 0.62 10.7 0.0 4.8 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ41332.1 - 2.8e-07 31.0 0.0 4.7e-05 23.9 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41332.1 - 1.8e-06 27.8 0.3 4.1 8.3 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KXZ41333.1 - 1.3e-05 25.6 0.0 0.0066 17.0 0.0 2.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41333.1 - 3.4e-05 24.3 0.1 0.0043 17.6 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41333.1 - 0.00016 21.9 0.2 0.61 10.5 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41333.1 - 0.0022 18.3 0.0 1.4 9.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat F-box PF00646.33 KXZ41333.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXZ41333.1 - 0.13 12.1 0.2 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.25 KXZ41334.1 - 6.6e-09 35.5 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41334.1 - 0.052 12.8 0.0 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Hint PF01079.20 KXZ41335.1 - 2.4e-14 53.3 0.0 4.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Hint module DUF347 PF03988.12 KXZ41335.1 - 3 8.1 8.8 0.24 11.6 0.7 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) PHD PF00628.29 KXZ41336.1 - 1.5e-08 34.4 10.9 2.5e-08 33.7 10.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXZ41336.1 - 0.043 13.4 1.4 0.088 12.4 1.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KXZ41336.1 - 0.12 12.7 7.7 0.2 12.0 7.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-PHD-like PF15446.6 KXZ41336.1 - 0.12 12.0 1.2 0.56 9.8 1.2 2.2 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain FANCL_C PF11793.8 KXZ41336.1 - 0.77 10.0 5.5 1.4 9.1 5.5 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain DUF2379 PF09543.10 KXZ41337.1 - 0.12 12.6 1.1 0.28 11.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) THUMP PF02926.17 KXZ41337.1 - 0.13 12.3 0.0 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 THUMP domain Ccdc124 PF06244.12 KXZ41338.1 - 4.9e-33 114.4 39.1 8.8e-30 103.9 39.1 2.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 AAA_23 PF13476.6 KXZ41338.1 - 8.4 6.8 11.8 12 6.4 11.8 1.3 1 0 0 1 1 1 0 AAA domain DUF680 PF05079.12 KXZ41339.1 - 0.06 14.0 6.3 2.8 8.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF680) CHAP PF05257.16 KXZ41339.1 - 0.15 12.7 2.2 11 6.7 0.1 2.5 2 1 0 2 2 2 0 CHAP domain Retrotrans_gag PF03732.17 KXZ41340.1 - 0.098 12.9 2.0 0.21 11.9 0.1 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Hint PF01079.20 KXZ41341.1 - 2.2e-13 50.2 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Hint module GRIP PF01465.20 KXZ41344.1 - 5.5e-07 29.4 0.2 4.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 GRIP domain Gtr1_RagA PF04670.12 KXZ41344.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Aminotran_1_2 PF00155.21 KXZ41345.1 - 7.4e-42 143.8 0.0 1.5e-32 113.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXZ41345.1 - 0.067 11.7 0.0 0.24 9.9 0.0 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Exo_endo_phos PF03372.23 KXZ41346.1 - 1.2e-12 47.8 0.0 2.1e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PHD PF00628.29 KXZ41347.1 - 2.7e-08 33.6 1.1 2.7e-08 33.6 1.1 1.8 2 0 0 2 2 2 1 PHD-finger rve PF00665.26 KXZ41347.1 - 3.4e-08 33.7 0.1 9.3e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Prok-RING_1 PF14446.6 KXZ41347.1 - 0.023 14.6 0.7 0.052 13.5 0.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 KXZ41347.1 - 0.026 14.6 3.4 0.026 14.6 3.4 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXZ41347.1 - 0.081 13.2 4.8 0.095 13.0 1.9 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 KXZ41347.1 - 0.61 10.4 3.6 0.45 10.9 0.4 2.4 3 0 0 3 3 3 0 RING-like domain zf-RING_2 PF13639.6 KXZ41347.1 - 4 7.8 7.7 0.52 10.7 2.6 2.1 3 0 0 3 3 3 0 Ring finger domain Dus PF01207.17 KXZ41348.1 - 4.1e-11 42.5 0.0 6.8e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ATG16 PF08614.11 KXZ41349.1 - 0.0095 16.2 25.6 0.0095 16.2 25.6 3.3 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KXZ41349.1 - 0.17 10.7 59.9 0.1 11.5 15.9 3.6 1 1 2 3 3 3 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KXZ41349.1 - 0.28 11.0 11.2 1.6 8.5 3.6 2.9 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CC2-LZ PF16516.5 KXZ41349.1 - 0.29 11.5 47.7 0.087 13.2 15.1 4.6 2 2 1 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MBR1 PF17058.5 KXZ41349.1 - 8.7 6.6 8.2 1.1 9.5 3.2 1.9 1 1 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 Integrase_H2C2 PF17921.1 KXZ41350.1 - 8.5e-20 70.6 0.0 1.9e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KXZ41350.1 - 3.6e-14 53.0 0.0 1e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 KXZ41350.1 - 1.2e-12 48.0 0.4 2.5e-12 47.0 0.4 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PHD PF00628.29 KXZ41350.1 - 8.6e-06 25.6 5.2 8.6e-06 25.6 5.2 2.5 2 0 0 2 2 2 1 PHD-finger RT_RNaseH_2 PF17919.1 KXZ41350.1 - 8.9e-05 22.5 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 KXZ41350.1 - 0.00038 20.6 0.0 0.0008 19.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 KXZ41350.1 - 0.019 14.7 0.0 0.061 13.1 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain zf-HC5HC2H PF13771.6 KXZ41350.1 - 0.028 14.7 1.8 0.06 13.6 1.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 KXZ41350.1 - 0.19 12.1 5.1 0.46 10.8 1.7 2.4 2 0 0 2 2 2 0 RING-like domain RVT_1 PF00078.27 KXZ41351.1 - 5e-18 65.4 0.0 9.8e-18 64.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 KXZ41351.1 - 2.3e-09 37.4 0.0 4.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 KXZ41351.1 - 4e-09 36.9 0.2 1e-08 35.6 0.2 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 KXZ41351.1 - 1.9e-07 31.1 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 KXZ41351.1 - 8.8e-07 29.5 0.5 2.5e-06 28.0 0.5 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KXZ41351.1 - 0.00054 19.8 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KXZ41351.1 - 0.00062 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KXZ41351.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease SSF PF00474.17 KXZ41352.1 - 1.2e-29 103.4 21.4 2e-29 102.7 21.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Dirigent PF03018.14 KXZ41354.1 - 0.00052 19.8 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Dirigent-like protein Allene_ox_cyc PF06351.11 KXZ41354.1 - 0.00091 19.0 0.2 0.0011 18.8 0.2 1.1 1 0 0 1 1 1 1 Allene oxide cyclase RT_RNaseH_2 PF17919.1 KXZ41356.1 - 2.6e-23 81.9 0.0 4.9e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ41356.1 - 1.3e-18 67.3 0.0 2.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KXZ41356.1 - 1.3e-15 57.5 0.0 2.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KXZ41356.1 - 4.2e-12 46.0 0.1 8.8e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KXZ41356.1 - 2.7e-11 43.7 0.0 1.8e-10 41.0 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain PHD PF00628.29 KXZ41356.1 - 6e-11 42.1 1.7 6e-11 42.1 1.7 1.9 2 0 0 2 2 2 1 PHD-finger zf-H2C2 PF09337.10 KXZ41356.1 - 1e-05 25.7 0.1 2.4e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger EF-hand_5 PF13202.6 KXZ41358.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KXZ41358.1 - 0.027 14.0 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 EF hand Dockerin_1 PF00404.18 KXZ41358.1 - 0.079 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_6 PF13405.6 KXZ41358.1 - 0.084 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DUF4257 PF14074.6 KXZ41358.1 - 0.12 12.6 0.7 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) DUF2749 PF10907.8 KXZ41358.1 - 2.6 8.3 5.6 2 8.6 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) LapA_dom PF06305.11 KXZ41358.1 - 4.2 7.3 7.4 0.59 10.0 0.9 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ank_2 PF12796.7 KXZ41359.1 - 2.3e-08 34.5 0.1 0.0046 17.5 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41359.1 - 0.0026 18.3 7.5 0.11 13.1 2.0 4.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41359.1 - 0.012 15.9 6.8 30 5.1 0.0 5.0 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41359.1 - 0.013 16.0 2.8 31 5.6 0.1 5.5 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 KXZ41360.1 - 6.7e-06 26.6 0.4 0.12 13.0 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41360.1 - 1e-05 26.0 4.7 0.6 10.8 0.0 6.2 4 1 3 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41360.1 - 0.0092 16.4 2.0 47 5.0 0.0 5.8 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 KXZ41360.1 - 0.041 14.2 5.8 24 5.4 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Cut8 PF08559.10 KXZ41360.1 - 0.15 11.6 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein ATX_III PF08098.11 KXZ41360.1 - 4.3 7.5 8.2 16 5.6 1.2 3.4 3 0 0 3 3 3 0 Anemonia sulcata toxin III family TFIIA PF03153.13 KXZ41363.1 - 1.3 8.9 23.4 5 7.0 5.2 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WW PF00397.26 KXZ41364.1 - 1e-17 63.9 31.6 5.9e-07 29.5 0.1 5.7 5 0 0 5 5 5 3 WW domain Ank_5 PF13857.6 KXZ41364.1 - 2.5e-07 30.8 0.0 0.01 16.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ41364.1 - 7.7e-07 29.6 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ntox37 PF15535.6 KXZ41364.1 - 0.008 16.6 3.8 1.9 9.0 0.2 4.1 3 1 0 3 3 3 1 Bacterial toxin 37 Ank_3 PF13606.6 KXZ41364.1 - 0.0095 16.4 0.0 4.1 8.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXZ41364.1 - 0.013 16.1 0.0 0.94 10.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Glyco_hyd_101C PF17451.2 KXZ41364.1 - 0.029 14.7 14.8 0.042 14.1 1.8 3.4 2 2 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Collagen_bind_2 PF12904.7 KXZ41364.1 - 0.9 9.6 11.8 6.9 6.7 0.1 4.3 1 1 3 4 4 4 0 Putative collagen-binding domain of a collagenase PQQ PF01011.21 KXZ41364.1 - 7.4 6.7 6.8 28 4.9 0.1 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat TPR_12 PF13424.6 KXZ41368.1 - 2.8e-29 101.2 6.0 6.6e-14 52.0 0.4 4.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ41368.1 - 1.6e-26 91.3 3.5 7.1e-13 48.0 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat UVR PF02151.19 KXZ41368.1 - 1.1e-07 31.4 16.3 0.00031 20.4 4.4 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif TPR_7 PF13176.6 KXZ41368.1 - 6.2e-06 25.9 0.6 3.2e-05 23.7 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ41368.1 - 5.4e-05 22.8 0.4 0.00072 19.3 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ41368.1 - 0.00042 20.9 0.7 0.26 12.2 0.1 3.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ41368.1 - 0.0016 18.5 1.9 0.0022 18.1 0.6 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ41368.1 - 0.0019 18.2 0.1 0.76 10.1 0.2 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT PF02985.22 KXZ41368.1 - 0.0056 16.8 0.8 5.8 7.5 0.1 3.8 3 0 0 3 3 3 1 HEAT repeat CLASP_N PF12348.8 KXZ41368.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.6 1 1 0 1 1 1 0 CLASP N terminal TPR_4 PF07721.14 KXZ41368.1 - 0.034 14.7 0.1 0.8 10.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ41368.1 - 0.052 14.2 0.3 0.052 14.2 0.3 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ41368.1 - 0.09 12.9 6.6 0.29 11.4 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 KXZ41368.1 - 0.11 13.1 0.3 3.1 8.4 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat K_channel_TID PF07941.11 KXZ41368.1 - 7.9 7.0 11.2 1.3 9.6 3.9 3.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain COR PF16095.5 KXZ41369.1 - 5.9e-21 75.2 0.0 8.6e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 KXZ41369.1 - 9.7e-17 61.3 0.0 1.6e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ41369.1 - 1.7e-07 30.9 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ41369.1 - 4.1e-07 29.6 0.0 7.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 KXZ41369.1 - 0.014 15.7 0.0 0.055 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXZ41369.1 - 0.043 13.4 0.1 0.13 11.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXZ41369.1 - 0.051 13.0 0.3 0.13 11.6 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ41369.1 - 0.1 13.0 0.5 0.63 10.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain adh_short PF00106.25 KXZ41370.1 - 1.2e-07 31.4 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ41370.1 - 3.1e-06 26.9 0.0 3.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Olfactory_mark PF06554.12 KXZ41370.1 - 0.19 11.5 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Olfactory marker protein FKBP_C PF00254.28 KXZ41371.1 - 2.3e-22 79.1 0.0 6e-20 71.4 0.0 2.2 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Lipase_3 PF01764.25 KXZ41373.1 - 3.3e-11 43.2 0.0 8.5e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) Pan_kinase PF03309.14 KXZ41373.1 - 0.091 12.6 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Type III pantothenate kinase Pkinase PF00069.25 KXZ41374.1 - 2.4e-14 53.3 0.0 2.7e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41374.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KXZ41374.1 - 0.0019 17.9 0.0 0.0023 17.6 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXZ41374.1 - 0.021 13.6 0.0 0.024 13.4 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXZ41374.1 - 0.065 13.1 0.6 0.098 12.6 0.6 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family 5_nucleotid_C PF02872.18 KXZ41375.1 - 1.2e-70 236.8 0.0 2.3e-34 118.9 0.0 2.1 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain TcfC PF16967.5 KXZ41375.1 - 0.1 12.1 0.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 E-set like domain RTC_insert PF05189.13 KXZ41375.1 - 0.12 12.8 0.0 41 4.8 0.0 2.9 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain PaREP1 PF05942.11 KXZ41375.1 - 1.1 9.2 3.5 23 4.9 0.3 2.2 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family UBA_4 PF14555.6 KXZ41377.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain PfkB PF00294.24 KXZ41378.1 - 1.5e-15 57.3 2.6 1.5e-15 57.3 2.6 3.1 2 1 1 3 3 3 1 pfkB family carbohydrate kinase Kdo PF06293.14 KXZ41378.1 - 0.0056 16.1 0.1 0.38 10.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ41378.1 - 0.022 14.7 21.8 0.034 14.1 7.7 4.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ41378.1 - 0.08 11.7 0.0 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KXZ41378.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 PMD PF10536.9 KXZ41378.1 - 2.4 7.2 4.9 4 6.5 4.9 1.3 1 0 0 1 1 1 0 Plant mobile domain Abhydrolase_3 PF07859.13 KXZ41379.1 - 1.5e-17 64.2 16.2 3.9e-17 62.8 5.0 3.7 3 1 0 3 3 3 2 alpha/beta hydrolase fold COesterase PF00135.28 KXZ41379.1 - 3.8e-13 49.2 1.5 1.5e-12 47.2 1.5 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXZ41379.1 - 3.9e-07 29.8 0.0 0.012 15.1 0.1 3.0 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KXZ41379.1 - 0.00031 19.7 0.0 0.00064 18.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXZ41379.1 - 0.029 13.6 6.8 0.18 11.0 0.7 2.9 3 1 1 4 4 4 0 Serine aminopeptidase, S33 VOMI PF03762.17 KXZ41380.1 - 1.8e-31 109.6 3.3 6.8e-31 107.7 3.2 2.0 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) RicinB_lectin_2 PF14200.6 KXZ41380.1 - 5.1e-07 30.3 0.9 1.7e-06 28.7 0.9 1.9 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ41380.1 - 0.00089 19.5 0.1 0.0019 18.5 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ank_4 PF13637.6 KXZ41381.1 - 2e-28 98.4 0.1 6.1e-09 36.2 0.0 4.5 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ41381.1 - 3.8e-27 94.7 0.1 1.1e-11 45.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ41381.1 - 6.2e-26 90.1 2.8 1.7e-09 37.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41381.1 - 2.3e-25 87.9 2.0 7.5e-08 32.5 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KXZ41381.1 - 3.6e-22 76.1 0.3 3.5e-05 23.9 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat UBA PF00627.31 KXZ41381.1 - 0.074 13.0 2.4 12 6.0 0.2 3.4 3 0 0 3 3 3 0 UBA/TS-N domain DUF3707 PF12499.8 KXZ41383.1 - 6.1e-18 65.7 1.3 1e-17 65.0 1.3 1.3 1 0 0 1 1 1 1 Pherophorin DnaJ PF00226.31 KXZ41384.1 - 1.7e-26 92.1 4.2 2.4e-26 91.6 4.2 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KXZ41384.1 - 4.1e-25 88.6 0.0 6.3e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain LprI PF07007.12 KXZ41384.1 - 0.13 12.9 1.2 0.24 12.1 1.2 1.3 1 0 0 1 1 1 0 Lysozyme inhibitor LprI ArgoL1 PF08699.10 KXZ41385.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Argonaute linker 1 domain WW PF00397.26 KXZ41386.1 - 4.5e-07 29.8 0.5 9.6e-07 28.8 0.5 1.5 1 0 0 1 1 1 1 WW domain DUF4366 PF14283.6 KXZ41386.1 - 0.02 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CcmH PF03918.14 KXZ41386.1 - 0.026 13.8 0.2 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF1358 PF07096.11 KXZ41386.1 - 0.068 13.2 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) Tad PF13400.6 KXZ41386.1 - 0.59 10.5 0.0 0.59 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like SecY PF00344.20 KXZ41387.1 - 1.9e-19 70.0 4.8 1.3e-10 41.1 1.8 2.9 1 1 1 2 2 2 2 SecY translocase WD40 PF00400.32 KXZ41388.1 - 2.6e-17 62.9 12.1 0.089 13.7 1.9 8.8 9 0 0 9 9 9 4 WD domain, G-beta repeat Ion_trans PF00520.31 KXZ41388.1 - 5.3e-16 58.6 5.7 7.3e-16 58.1 5.7 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXZ41388.1 - 1.7e-07 30.3 1.0 1.7e-07 30.3 1.0 2.9 2 1 1 3 3 3 2 Polycystin cation channel ANAPC4_WD40 PF12894.7 KXZ41388.1 - 0.0062 16.8 0.2 1.1 9.6 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Siah-Interact_N PF09032.11 KXZ41388.1 - 0.02 15.2 0.5 0.037 14.3 0.5 1.4 1 0 0 1 1 1 0 Siah interacting protein, N terminal TSP9 PF11493.8 KXZ41388.1 - 0.099 13.3 0.5 0.23 12.2 0.5 1.6 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Val_tRNA-synt_C PF10458.9 KXZ41389.1 - 0.057 13.7 0.9 0.17 12.2 0.3 2.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Ammonium_transp PF00909.21 KXZ41390.1 - 2.4e-26 92.4 7.8 2.7e-26 92.2 7.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Histone_H2A_C PF16211.5 KXZ41391.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ41391.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ41391.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ41392.1 - 6.7e-23 81.5 5.3 8.6e-23 81.1 5.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ41392.1 - 2.5e-05 24.4 0.1 8.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ41392.1 - 0.0019 18.7 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ41392.1 - 0.0057 16.7 5.1 0.0081 16.2 5.1 1.3 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 KXZ41392.1 - 0.017 14.7 0.6 0.73 9.5 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ41392.1 - 5.5 7.5 11.6 22 5.6 11.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Ank_2 PF12796.7 KXZ41393.1 - 1.2e-17 64.2 0.1 1.4e-06 28.8 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41393.1 - 6.8e-16 56.8 0.1 1.9e-05 24.7 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KXZ41393.1 - 2e-12 47.0 0.1 0.0011 19.3 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXZ41393.1 - 2.4e-11 43.9 0.4 0.00029 21.3 0.0 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41393.1 - 3e-10 40.2 2.2 0.0015 18.8 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 KXZ41393.1 - 2.1e-05 23.9 8.8 3.9e-05 23.0 8.8 1.3 1 0 0 1 1 1 1 Ion transport protein DUF1682 PF07946.14 KXZ41395.1 - 3.9e-59 200.5 0.0 4.4e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) YqfQ PF14181.6 KXZ41395.1 - 0.074 13.2 0.8 0.14 12.3 0.8 1.4 1 0 0 1 1 1 0 YqfQ-like protein DUF3301 PF11743.8 KXZ41395.1 - 0.14 11.8 1.1 0.63 9.8 1.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) HAT PF02184.16 KXZ41396.1 - 6.1e-18 64.5 40.7 5.5e-09 35.8 0.3 7.8 8 0 0 8 8 8 4 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 KXZ41396.1 - 2.7e-08 33.3 5.9 0.027 14.5 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ41396.1 - 1e-07 32.2 18.1 0.0052 17.5 0.1 6.4 2 1 5 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXZ41396.1 - 3.3e-05 23.9 11.2 0.044 13.8 0.2 4.3 4 1 0 4 4 4 2 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 KXZ41396.1 - 5.6e-05 23.6 0.1 0.59 10.7 0.0 3.6 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ41396.1 - 0.00034 21.2 12.4 0.14 12.8 0.8 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ41396.1 - 0.00061 19.1 5.6 0.11 11.7 0.2 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 KXZ41396.1 - 0.00097 19.2 12.1 0.052 13.5 3.5 4.2 1 1 3 4 4 4 2 Suppressor of forked protein (Suf) TAtT PF16811.5 KXZ41396.1 - 0.018 14.3 5.0 3.2 7.0 0.1 3.6 2 1 1 3 3 3 0 TRAP transporter T-component TPR_9 PF13371.6 KXZ41396.1 - 0.027 14.6 8.3 0.57 10.4 0.3 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ41396.1 - 0.061 13.6 6.0 1.9 8.8 0.5 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ41396.1 - 0.11 12.7 1.8 1.4 9.3 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat XPB_DRD PF18458.1 KXZ41396.1 - 0.18 11.7 2.9 0.94 9.4 0.9 3.0 2 1 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain TPR_6 PF13174.6 KXZ41396.1 - 0.19 12.4 6.9 87 4.1 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Roc PF08477.13 KXZ41397.1 - 5.9e-17 62.0 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ41397.1 - 1.8e-12 47.5 0.0 2.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_2 PF12796.7 KXZ41397.1 - 5.8e-07 30.0 0.0 2.5e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ras PF00071.22 KXZ41397.1 - 7.5e-07 28.9 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Ank PF00023.30 KXZ41397.1 - 6.4e-06 26.4 0.0 0.0017 18.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXZ41397.1 - 2.9e-05 24.2 0.0 6.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Arf PF00025.21 KXZ41397.1 - 3.3e-05 23.4 0.0 5.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_3 PF13606.6 KXZ41397.1 - 0.00031 20.9 0.0 0.015 15.8 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXZ41397.1 - 0.0027 18.3 0.0 0.031 14.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Mg_chelatase PF01078.21 KXZ41397.1 - 0.063 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRPRB PF09439.10 KXZ41397.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dimer_Tnp_hAT PF05699.14 KXZ41399.1 - 6.3e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2397 PF09660.10 KXZ41399.1 - 0.18 10.7 4.7 1.2 8.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) 2OG-FeII_Oxy_4 PF13661.6 KXZ41400.1 - 0.13 12.9 0.0 0.14 12.8 0.0 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Guanylate_cyc PF00211.20 KXZ41402.1 - 2.4e-49 167.5 0.0 4.3e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fer4_15 PF13459.6 KXZ41402.1 - 0.12 13.2 0.7 0.38 11.5 0.3 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain SAE2 PF08573.10 KXZ41403.1 - 3e-11 44.4 0.0 3e-11 44.4 0.0 4.5 5 1 0 5 5 5 1 DNA repair protein endonuclease SAE2/CtIP C-terminus ALMT PF11744.8 KXZ41403.1 - 2.8 6.7 5.9 4.9 5.9 5.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-MYND PF01753.18 KXZ41404.1 - 4.6e-10 39.4 10.2 8.3e-10 38.6 10.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ41404.1 - 0.31 11.4 7.8 0.51 10.7 7.8 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DEAD PF00270.29 KXZ41405.1 - 2.2e-17 63.4 0.0 9.5e-17 61.3 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ41405.1 - 8.6e-12 45.4 0.1 2.4e-11 43.9 0.0 1.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 KXZ41405.1 - 0.0036 17.3 2.8 0.0036 17.3 2.8 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 KXZ41405.1 - 0.12 12.1 1.4 0.43 10.4 1.4 1.9 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 KXZ41405.1 - 0.13 12.0 0.6 0.3 10.9 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle RNA_pol_3_Rpc31 PF11705.8 KXZ41406.1 - 0.81 9.9 7.8 1.7 8.9 7.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Coa1 PF08695.10 KXZ41409.1 - 0.047 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 BK_channel_a PF03493.18 KXZ41411.1 - 1.2e-10 41.5 0.0 3.3e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Trypan_PARP PF05887.11 KXZ41411.1 - 0.00011 22.2 97.0 0.0011 19.0 43.2 2.9 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) COR PF16095.5 KXZ41414.1 - 3.2e-15 56.4 0.0 4.3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain PALP PF00291.25 KXZ41417.1 - 3.6e-55 187.5 12.2 6.1e-55 186.7 12.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LMWPc PF01451.21 KXZ41418.1 - 1.3e-20 74.2 0.0 1.1e-18 67.9 0.0 2.8 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase B_lectin PF01453.24 KXZ41419.1 - 3e-07 30.9 0.0 0.00029 21.3 0.0 1.8 1 1 1 2 2 2 2 D-mannose binding lectin bZIP_1 PF00170.21 KXZ41420.1 - 1.1e-08 35.0 6.2 1.8e-08 34.3 6.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ41420.1 - 6.2e-08 32.6 9.1 1.1e-07 31.9 9.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXZ41420.1 - 3.6e-06 27.4 4.0 7.4e-06 26.4 4.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor IATP PF04568.12 KXZ41420.1 - 0.0093 16.4 3.9 0.015 15.7 3.9 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Nnf1 PF03980.14 KXZ41420.1 - 0.37 11.2 8.1 1.9 8.9 8.1 2.0 1 1 0 1 1 1 0 Nnf1 RVT_1 PF00078.27 KXZ41422.1 - 5e-16 58.9 0.0 1.2e-13 51.1 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 KXZ41422.1 - 0.11 12.7 0.5 0.67 10.3 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein APG6 PF04111.12 KXZ41423.1 - 9.6e-49 165.7 0.0 1.3e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KXZ41423.1 - 7.3e-05 23.3 0.2 0.00017 22.1 0.1 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region CDC45 PF02724.14 KXZ41424.1 - 1.1 7.5 8.2 2.2 6.4 8.2 1.4 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 KXZ41424.1 - 3.7 6.4 8.1 7 5.4 8.1 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pkinase PF00069.25 KXZ41425.1 - 3.2e-42 144.7 0.0 4.6e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41425.1 - 6.2e-21 74.9 0.0 9.7e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KXZ41425.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KXZ41425.1 - 0.0042 17.1 0.0 0.0042 17.1 0.0 4.0 2 2 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 KXZ41425.1 - 0.0058 16.0 0.0 0.0058 16.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-ribbon_3 PF13248.6 KXZ41426.1 - 0.14 11.6 1.1 0.23 10.9 0.3 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Histone_H2A_C PF16211.5 KXZ41428.1 - 3.1e-19 68.4 2.2 5.5e-19 67.6 2.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ41428.1 - 1.8e-16 60.7 0.0 2.3e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ41428.1 - 5.8e-05 23.3 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ41429.1 - 1.3e-09 38.5 0.0 1.6e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KXZ41429.1 - 0.08 13.4 0.1 0.13 12.7 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KXZ41429.1 - 0.089 13.1 0.3 0.16 12.3 0.1 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 KXZ41430.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ41430.1 - 1.6e-16 60.8 0.0 2.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ41430.1 - 5.7e-05 23.3 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Laminin_II PF06009.12 KXZ41431.1 - 0.023 14.7 2.5 0.045 13.8 2.1 1.7 1 1 0 1 1 1 0 Laminin Domain II CENP-F_leu_zip PF10473.9 KXZ41431.1 - 0.026 14.5 1.5 0.042 13.9 1.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 KXZ41431.1 - 0.052 14.0 0.4 0.081 13.3 0.4 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Mod_r PF07200.13 KXZ41431.1 - 0.082 13.0 1.0 0.11 12.7 1.0 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein COG5 PF10392.9 KXZ41431.1 - 0.084 13.1 0.9 0.12 12.6 0.9 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 ATP-synt_ab_C PF00306.27 KXZ41431.1 - 0.094 13.0 0.4 0.15 12.4 0.4 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain HAUS-augmin3 PF14932.6 KXZ41431.1 - 0.12 12.0 0.2 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 KXZ41431.1 - 0.14 12.2 1.1 0.18 11.8 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spore_II_R PF09551.10 KXZ41431.1 - 0.22 12.0 0.9 0.28 11.6 0.4 1.4 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) RLI PF04068.15 KXZ41432.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI UvrA_DNA-bind PF17755.1 KXZ41432.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 UvrA DNA-binding domain PHD PF00628.29 KXZ41434.1 - 2.4e-06 27.3 1.2 6e-06 26.1 1.2 1.7 1 0 0 1 1 1 1 PHD-finger FOXO-TAD PF16676.5 KXZ41434.1 - 0.08 13.4 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 Transactivation domain of FOXO protein family RRM_1 PF00076.22 KXZ41439.1 - 9.1e-26 89.5 0.0 2.9e-21 75.1 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ41439.1 - 0.0038 17.3 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 KXZ41439.1 - 0.21 11.7 0.0 0.63 10.1 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 TP6A_N PF04406.14 KXZ41440.1 - 2.8e-21 75.3 0.0 4.7e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Ph1570 PF09638.10 KXZ41440.1 - 0.019 14.8 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 Ph1570 protein DUF3837 PF12939.7 KXZ41440.1 - 0.026 14.9 0.2 0.054 13.9 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) RNA_pol_N PF01194.17 KXZ41440.1 - 0.094 13.0 0.4 22 5.4 0.0 2.5 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit DEAD PF00270.29 KXZ41443.1 - 6.6e-39 133.5 0.0 4.8e-38 130.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ41443.1 - 3.8e-29 101.3 0.2 1.2e-26 93.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ41443.1 - 5.3e-08 33.1 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXZ41443.1 - 0.0013 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KXZ41443.1 - 0.017 14.4 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF4844 PF16133.5 KXZ41443.1 - 0.042 14.4 2.1 0.13 12.8 0.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4844) Abhydrolase_6 PF12697.7 KXZ41444.1 - 3e-30 106.5 17.8 1.6e-15 58.3 5.5 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ41444.1 - 1.2e-23 84.1 2.4 3.2e-10 40.1 0.4 3.1 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ41444.1 - 1.8e-22 79.8 0.6 1.2e-09 37.8 0.1 3.3 3 1 0 3 3 3 2 Serine aminopeptidase, S33 Lipase_2 PF01674.18 KXZ41444.1 - 0.005 16.4 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 2) Thioesterase PF00975.20 KXZ41444.1 - 0.13 12.3 2.0 5 7.2 0.2 2.2 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 KXZ41444.1 - 0.14 11.8 0.1 21 4.8 0.0 2.7 2 0 0 2 2 2 0 PGAP1-like protein DUF915 PF06028.11 KXZ41444.1 - 0.15 11.4 0.1 20 4.4 0.0 3.0 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF915) PSI_integrin PF17205.3 KXZ41444.1 - 0.53 10.1 1.6 32 4.4 0.1 2.4 2 0 0 2 2 2 0 Integrin plexin domain Proteasome_A_N PF10584.9 KXZ41446.1 - 4.2e-15 55.1 0.1 6.6e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Proteasome PF00227.26 KXZ41446.1 - 1.6e-05 24.5 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit COX6B PF02297.17 KXZ41447.1 - 6.4e-15 55.2 7.3 8.4e-15 54.8 7.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KXZ41447.1 - 0.0063 16.6 4.7 0.0097 16.0 4.7 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KXZ41447.1 - 0.059 13.4 4.5 0.1 12.6 4.5 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SOUL PF04832.12 KXZ41448.1 - 3.9e-39 134.5 0.0 6e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 SOUL heme-binding protein DUF2358 PF10184.9 KXZ41448.1 - 2.2e-14 53.7 0.0 3.5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KXZ41448.1 - 0.0037 17.9 0.1 0.012 16.3 0.1 1.8 1 0 0 1 1 1 1 SnoaL-like domain Ribosomal_S3Ae PF01015.18 KXZ41449.1 - 1.2e-96 322.1 4.3 1.4e-96 321.9 4.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Phage_TAC_5 PF08890.11 KXZ41449.1 - 0.013 15.5 1.4 0.44 10.5 0.0 2.5 1 1 1 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC SUI1 PF01253.22 KXZ41449.1 - 0.015 15.8 0.4 3.7 8.1 0.1 3.0 3 0 0 3 3 3 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 KXZ41449.1 - 0.05 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region His_Phos_2 PF00328.22 KXZ41450.1 - 3.3e-15 56.3 0.0 2.2e-11 43.7 0.0 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) HTH_28 PF13518.6 KXZ41451.1 - 0.071 13.2 0.2 0.094 12.9 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Cyclin_N PF00134.23 KXZ41452.1 - 0.046 13.5 0.0 0.048 13.4 0.0 1.3 1 1 0 1 1 1 0 Cyclin, N-terminal domain Pkinase PF00069.25 KXZ41453.1 - 1.5e-40 139.2 0.0 1.7e-32 112.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41453.1 - 6e-36 124.1 0.0 3.3e-27 95.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ41453.1 - 0.00069 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ41453.1 - 0.018 14.9 1.2 0.11 12.4 1.2 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ41453.1 - 0.032 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ41453.1 - 0.04 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXZ41453.1 - 0.042 12.8 0.0 0.093 11.7 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KXZ41453.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Helitron_like_N PF14214.6 KXZ41455.1 - 1.1e-12 48.5 0.0 2.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Tegument_dsDNA PF12818.7 KXZ41455.1 - 0.038 13.1 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 dsDNA viral tegument protein TPR_10 PF13374.6 KXZ41457.1 - 1.1e-81 266.7 109.0 3.3e-11 42.7 0.3 17.6 18 0 0 18 18 18 14 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ41457.1 - 1.9e-80 265.2 90.2 1.9e-16 60.1 3.6 12.3 6 4 6 12 12 12 12 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ41457.1 - 4.3e-18 65.8 60.8 2.2e-11 43.7 7.8 6.7 3 2 2 5 5 5 3 MalT-like TPR region TPR_7 PF13176.6 KXZ41457.1 - 1.1e-15 56.4 63.1 0.0039 17.1 0.2 13.5 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ41457.1 - 1.2e-15 56.3 20.6 0.61 10.5 0.0 12.2 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ41457.1 - 1.3e-15 56.5 26.7 0.033 14.0 0.2 10.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ41457.1 - 4.6e-13 48.2 59.9 0.3 11.3 0.2 13.5 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ41457.1 - 5.5e-10 39.6 73.4 0.022 15.3 0.3 10.6 8 2 2 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ41457.1 - 1.3e-08 34.9 126.7 0.026 15.3 2.8 16.9 10 4 7 17 17 17 8 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ41457.1 - 7.7e-08 32.2 148.1 0.00048 20.5 5.6 18.2 19 0 0 19 19 17 11 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ41457.1 - 1.6e-07 31.9 125.0 0.0067 17.1 5.8 15.9 9 4 5 14 14 13 9 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ41457.1 - 3.3e-06 27.2 14.6 0.29 11.4 0.2 7.3 5 2 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXZ41457.1 - 0.097 13.1 23.6 16 6.1 0.0 9.7 11 0 0 11 11 9 0 Tetratricopeptide repeat Helitron_like_N PF14214.6 KXZ41459.1 - 1.4e-12 48.3 0.0 3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Tegument_dsDNA PF12818.7 KXZ41459.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 dsDNA viral tegument protein 3HCDH_RFF PF18321.1 KXZ41461.1 - 0.37 11.3 0.2 0.37 11.3 0.2 2.3 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Cyclin_C_2 PF16899.5 KXZ41462.1 - 0.014 15.8 0.0 0.048 14.1 0.0 1.9 1 1 0 1 1 1 0 Cyclin C-terminal domain Ribosomal_60s PF00428.19 KXZ41462.1 - 0.043 14.4 3.8 0.07 13.7 3.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein GCHY-1 PF02649.14 KXZ41462.1 - 0.2 11.2 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Cyclin_N PF00134.23 KXZ41463.1 - 1e-09 38.2 0.0 1.5e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain Helitron_like_N PF14214.6 KXZ41464.1 - 1.8e-11 44.6 0.0 4.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.6 KXZ41464.1 - 0.00083 19.7 0.0 0.0024 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ41464.1 - 0.025 15.0 0.0 0.025 15.0 0.0 4.9 4 2 0 4 4 4 0 AAA ATPase domain AAA_21 PF13304.6 KXZ41464.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system REJ PF02010.15 KXZ41465.1 - 1.4e-09 37.3 0.1 3.1e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 REJ domain FAST_1 PF06743.15 KXZ41466.1 - 0.095 12.7 0.7 1.2 9.1 0.7 2.2 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Ins134_P3_kin PF05770.11 KXZ41468.1 - 9.6e-28 97.1 0.0 1e-22 80.6 0.0 3.1 2 1 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 KXZ41468.1 - 0.0012 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Herpes_U47 PF05467.11 KXZ41468.1 - 0.74 7.9 3.7 1.2 7.2 3.7 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 TraC PF07820.12 KXZ41468.1 - 4.1 7.8 11.6 2.7 8.4 0.6 3.7 3 0 0 3 3 3 0 TraC-like protein TPM_phosphatase PF04536.14 KXZ41469.1 - 3.5e-17 62.7 0.4 5.1e-17 62.2 0.4 1.2 1 0 0 1 1 1 1 TPM domain SMC_Nse1 PF07574.13 KXZ41470.1 - 1e-18 67.9 0.0 2e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex TAL_FSA PF00923.19 KXZ41471.1 - 2.1e-14 53.6 0.0 3.4e-14 52.9 0.0 1.3 1 1 1 2 2 2 1 Transaldolase/Fructose-6-phosphate aldolase TSA PF03249.13 KXZ41471.1 - 0.043 12.6 0.1 0.055 12.3 0.1 1.1 1 0 0 1 1 1 0 Type specific antigen Cation_ATPase_C PF00689.21 KXZ41472.1 - 5.5e-48 163.1 2.1 7.4e-48 162.7 2.1 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus RVT_1 PF00078.27 KXZ41473.1 - 1.7e-20 73.5 0.0 2.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KXZ41473.1 - 5.2e-14 52.1 0.0 9.9e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ41473.1 - 9.3e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ41475.1 - 4.2e-11 42.8 0.0 6.6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HRM PF02793.22 KXZ41476.1 - 0.017 15.4 0.1 0.051 13.9 0.1 1.8 1 0 0 1 1 1 0 Hormone receptor domain DEC-1_N PF04625.13 KXZ41476.1 - 0.63 9.0 3.1 1.3 8.0 3.1 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Flagellar_rod PF05149.12 KXZ41477.1 - 0.033 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein Exonuc_VII_S PF02609.16 KXZ41477.1 - 0.071 13.2 2.2 2.2 8.4 0.0 3.1 2 1 1 3 3 3 0 Exonuclease VII small subunit AAA_16 PF13191.6 KXZ41479.1 - 0.00023 21.6 0.2 0.00068 20.1 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXZ41479.1 - 0.18 12.0 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Tctex-1 PF03645.13 KXZ41480.1 - 1.2e-22 80.0 0.8 2e-22 79.4 0.8 1.3 1 0 0 1 1 1 1 Tctex-1 family PSCyt2 PF07583.11 KXZ41480.1 - 0.17 11.8 0.2 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) COR PF16095.5 KXZ41482.1 - 4e-23 82.2 0.0 4.9e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain FTR1 PF03239.14 KXZ41484.1 - 1.1e-32 113.4 10.7 1.4e-16 60.6 6.7 2.3 2 1 0 2 2 2 2 Iron permease FTR1 family Transmemb_17 PF09799.9 KXZ41484.1 - 0.007 16.9 0.7 0.007 16.9 0.7 2.6 3 0 0 3 3 3 1 Predicted membrane protein DUF2852 PF11014.8 KXZ41484.1 - 0.024 14.8 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) CcmH PF03918.14 KXZ41484.1 - 0.085 12.1 0.6 3.7 6.8 0.0 3.1 3 0 0 3 3 3 0 Cytochrome C biogenesis protein NiFe_hyd_3_EhaA PF17367.2 KXZ41484.1 - 0.46 10.7 6.5 0.28 11.4 0.2 2.8 2 1 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A Tmemb_14 PF03647.13 KXZ41484.1 - 4.8 8.0 11.3 1.6 9.6 5.1 2.5 2 0 0 2 2 2 0 Transmembrane proteins 14C Ank_2 PF12796.7 KXZ41486.1 - 1.9e-14 54.0 4.6 0.00081 19.9 0.3 4.5 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41486.1 - 6.1e-11 42.6 6.9 0.17 12.5 0.9 7.5 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41486.1 - 0.0011 19.3 10.1 2.9 8.3 0.0 6.8 5 1 2 7 7 7 1 Ankyrin repeats (many copies) DUF2695 PF10905.8 KXZ41486.1 - 0.013 15.7 0.0 0.32 11.3 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) DUF434 PF04256.12 KXZ41486.1 - 0.078 12.7 0.1 9 6.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF434) DUF1376 PF07120.11 KXZ41486.1 - 0.08 13.3 0.1 9.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) DUF2428 PF10350.9 KXZ41488.1 - 1.3e-30 106.6 0.0 2.3e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) DUF2730 PF10805.8 KXZ41489.1 - 0.0007 19.6 0.1 0.0009 19.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) HTH_19 PF12844.7 KXZ41489.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Pro_isomerase PF00160.21 KXZ41490.1 - 3.6e-20 72.8 0.0 3.8e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-MYND PF01753.18 KXZ41491.1 - 9.1e-06 25.7 7.9 1.8e-05 24.8 7.9 1.5 1 0 0 1 1 1 1 MYND finger Ribosomal_L20 PF00453.18 KXZ41492.1 - 3.5e-38 130.0 1.7 4.5e-38 129.6 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L20 DEC-1_N PF04625.13 KXZ41492.1 - 0.033 13.2 0.4 0.047 12.7 0.4 1.4 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region ABC_membrane_2 PF06472.15 KXZ41495.1 - 2.5e-35 122.2 0.3 6.2e-35 120.9 0.0 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXZ41495.1 - 3.1e-07 31.0 0.0 1e-06 29.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Ank_2 PF12796.7 KXZ41498.1 - 1.1e-26 93.2 0.0 6.1e-12 46.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ41498.1 - 2.8e-26 91.2 3.7 2.5e-07 30.9 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41498.1 - 1.8e-19 67.7 2.0 0.015 15.8 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KXZ41498.1 - 2.4e-18 66.3 0.9 3.8e-07 30.5 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41498.1 - 4e-16 58.6 10.8 0.034 14.6 0.1 6.2 5 0 0 5 5 5 5 Ankyrin repeat TetR_C_7 PF14246.6 KXZ41498.1 - 0.009 16.0 0.2 0.051 13.6 0.2 2.2 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain WD40 PF00400.32 KXZ41499.1 - 3.4e-47 157.4 28.0 1.8e-09 38.1 1.6 9.4 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ41499.1 - 3.4e-24 84.9 1.9 6.9e-07 29.5 0.4 7.4 4 2 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXZ41499.1 - 1.3e-17 63.2 0.2 0.0027 17.6 0.0 6.4 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXZ41499.1 - 1.9e-09 36.9 4.7 0.16 10.9 0.3 5.8 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 KXZ41499.1 - 2e-07 31.1 2.8 0.8 9.6 0.0 5.3 3 1 0 4 4 4 1 Transcription factor IIIC subunit delta N-term eIF2A PF08662.11 KXZ41499.1 - 1.4e-06 28.3 0.0 0.47 10.3 0.0 5.0 4 1 3 7 7 7 3 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 KXZ41499.1 - 4.5e-05 22.4 1.1 9.2 4.9 0.0 5.1 6 0 0 6 6 6 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.12 KXZ41499.1 - 0.00026 19.2 1.0 0.077 11.0 0.1 3.8 3 1 0 3 3 3 1 IKI3 family Proteasome_A_N PF10584.9 KXZ41499.1 - 0.00063 19.4 0.7 31 4.4 0.0 5.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KXZ41499.1 - 0.0007 18.4 2.3 2.9 6.4 0.0 4.1 3 1 0 4 4 4 1 Nucleoporin Nup120/160 SGL PF08450.12 KXZ41499.1 - 0.00079 19.1 1.2 1.8 8.1 0.4 3.8 2 2 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Coatomer_WDAD PF04053.14 KXZ41499.1 - 0.0014 17.8 0.0 12 4.7 0.0 4.1 4 0 0 4 4 4 1 Coatomer WD associated region PALB2_WD40 PF16756.5 KXZ41499.1 - 2.2 7.1 7.8 13 4.6 0.2 3.8 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain LEA_5 PF00477.17 KXZ41501.1 - 8.5e-05 23.0 6.2 0.00018 21.9 6.2 1.8 1 1 0 1 1 1 1 Small hydrophilic plant seed protein Pkinase PF00069.25 KXZ41504.1 - 1.8e-35 122.6 0.0 3.2e-35 121.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41504.1 - 2.1e-22 79.6 0.0 3.1e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ41504.1 - 4.5e-07 29.0 0.0 5.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ41504.1 - 0.0003 20.2 0.0 0.00039 19.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Helitron_like_N PF14214.6 KXZ41505.1 - 2.3e-12 47.5 0.0 4.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.6 KXZ41505.1 - 0.0095 16.3 0.0 0.0095 16.3 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 KXZ41505.1 - 0.035 13.9 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Phage_Orf51 PF06194.11 KXZ41505.1 - 0.041 13.9 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 AAA_22 PF13401.6 KXZ41505.1 - 0.061 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.6 KXZ41508.1 - 0.067 13.6 0.5 0.12 12.8 0.5 1.4 1 0 0 1 1 1 0 Snapin/Pallidin DUF2796 PF10986.8 KXZ41509.1 - 0.81 9.6 12.0 1 9.3 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DNA_pol_phi PF04931.13 KXZ41509.1 - 2.6 6.1 49.4 2.9 5.9 49.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2428 PF10350.9 KXZ41509.1 - 3 7.0 5.2 3.3 6.9 5.2 1.0 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) TFB6 PF17110.5 KXZ41509.1 - 4.5 7.0 17.0 5.5 6.7 17.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Helitron_like_N PF14214.6 KXZ41510.1 - 1.2e-11 45.2 0.0 2.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Lip_A_acyltrans PF03279.13 KXZ41510.1 - 0.00015 21.0 1.6 0.3 10.2 0.1 2.3 2 0 0 2 2 2 2 Bacterial lipid A biosynthesis acyltransferase MethyTransf_Reg PF10119.9 KXZ41510.1 - 0.0033 18.1 0.5 11 6.8 0.1 3.6 3 0 0 3 3 3 2 Predicted methyltransferase regulatory domain SUKH-4 PF14435.6 KXZ41510.1 - 0.02 14.9 7.9 7.3 6.6 0.1 4.7 4 0 0 4 4 4 0 SUKH-4 immunity protein BLACT_WH PF17778.1 KXZ41510.1 - 0.092 12.7 0.0 35 4.5 0.0 3.1 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain DUF2798 PF11391.8 KXZ41510.1 - 4.6 7.4 6.9 21 5.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2798) Methyltransf_12 PF08242.12 KXZ41511.1 - 0.02 15.6 0.0 0.031 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ctr PF04145.15 KXZ41512.1 - 8.8e-23 81.6 3.5 1.9e-22 80.5 3.5 1.5 1 1 0 1 1 1 1 Ctr copper transporter family CotH PF08757.11 KXZ41513.1 - 2.8e-34 119.1 0.0 5e-34 118.3 0.0 1.4 1 1 0 1 1 1 1 CotH kinase protein Ubie_methyltran PF01209.18 KXZ41514.1 - 1.8e-86 289.3 0.0 2.2e-85 285.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXZ41514.1 - 6.8e-17 61.9 0.0 2.4e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ41514.1 - 7.7e-17 61.8 0.0 2e-14 54.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ41514.1 - 1.5e-09 37.9 0.0 1.7e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ41514.1 - 7.6e-08 32.4 0.0 1.5e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ41514.1 - 2.8e-07 31.2 0.0 2.4e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXZ41514.1 - 0.011 15.6 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Inhibitor_I78 PF11720.8 KXZ41514.1 - 0.036 14.1 0.1 2 8.6 0.0 2.9 3 0 0 3 3 3 0 Peptidase inhibitor I78 family DUF3123 PF11321.8 KXZ41514.1 - 0.24 12.1 2.4 0.5 11.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF1180 PF06679.12 KXZ41514.1 - 3 8.2 8.0 10 6.5 8.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) PseudoU_synth_2 PF00849.22 KXZ41515.1 - 3.8e-17 62.8 0.0 6.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase DAO PF01266.24 KXZ41516.1 - 9.6e-36 124.1 2.3 1.7e-35 123.3 2.3 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase R3H PF01424.22 KXZ41518.1 - 0.0023 17.9 0.0 0.0068 16.4 0.0 1.7 2 0 0 2 2 2 1 R3H domain Ank_2 PF12796.7 KXZ41518.1 - 0.0023 18.5 0.4 0.0064 17.1 0.4 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ41518.1 - 0.01 16.1 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ald_Xan_dh_C2 PF02738.18 KXZ41520.1 - 0.04 12.4 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase DUF1180 PF06679.12 KXZ41520.1 - 0.31 11.5 5.2 0.43 11.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HEAT_2 PF13646.6 KXZ41520.1 - 1.1 9.7 7.5 0.23 11.9 4.1 1.5 2 0 0 2 2 2 0 HEAT repeats DUF155 PF02582.14 KXZ41522.1 - 9.1e-07 29.1 0.0 1e-06 29.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF155 PF02582.14 KXZ41524.1 - 3e-06 27.4 0.0 1.1e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF155 PF02582.14 KXZ41525.1 - 9.9e-11 42.0 1.1 5.9e-08 33.0 0.1 2.1 1 1 1 2 2 2 2 Uncharacterised ACR, YagE family COG1723 Occludin_ELL PF07303.13 KXZ41525.1 - 0.033 14.9 0.2 0.055 14.2 0.2 1.3 1 1 0 1 1 1 0 Occludin homology domain DUF1987 PF09345.10 KXZ41525.1 - 0.046 13.4 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Ank_4 PF13637.6 KXZ41528.1 - 1.7e-20 73.1 2.1 2.7e-05 24.6 0.0 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ41528.1 - 1.3e-18 67.3 0.8 2.8e-07 31.0 0.0 4.3 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41528.1 - 1.5e-14 52.6 5.8 0.36 11.5 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KXZ41528.1 - 6.9e-08 32.6 12.1 0.2 12.2 0.1 7.3 7 1 1 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KXZ41528.1 - 1.2e-05 25.5 16.2 0.058 13.7 0.3 5.9 4 2 4 8 8 8 3 Ankyrin repeats (many copies) MOZART1 PF12554.8 KXZ41528.1 - 0.091 12.6 0.2 10 6.0 0.0 3.2 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated MOLO1 PF17175.4 KXZ41529.1 - 1.7e-21 76.6 0.0 2.5e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 KXZ41529.1 - 1.4e-16 60.8 0.0 4.2e-16 59.3 0.0 1.7 2 0 0 2 2 1 1 TPM domain zf-C3HC4 PF00097.25 KXZ41529.1 - 6.3e-12 45.2 0.1 1.7e-11 43.8 0.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ41529.1 - 1.2e-11 44.5 0.0 6.8e-11 42.0 0.0 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXZ41529.1 - 2.5e-10 40.5 6.9 1.4e-08 34.9 3.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXZ41529.1 - 6.7e-10 38.8 0.5 3e-09 36.7 0.5 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXZ41529.1 - 1.4e-09 37.6 7.0 1.7e-09 37.4 2.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ41529.1 - 1.3e-08 34.5 7.8 3.8e-08 33.1 3.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXZ41529.1 - 3.7e-08 33.1 4.9 3.7e-08 33.1 4.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ41529.1 - 6.8e-08 32.7 1.2 6.8e-08 32.7 1.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXZ41529.1 - 5.8e-05 23.2 3.5 5.8e-05 23.2 3.5 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 KXZ41529.1 - 0.00021 21.1 0.6 0.2 11.5 0.1 2.3 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 KXZ41529.1 - 0.00025 21.0 0.2 0.00055 19.9 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXZ41529.1 - 0.0047 16.6 3.5 0.32 10.8 0.2 3.1 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_4 PF14570.6 KXZ41529.1 - 0.0065 16.2 3.0 0.0065 16.2 3.0 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain U-box PF04564.15 KXZ41529.1 - 0.033 14.4 0.1 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 U-box domain DZR PF12773.7 KXZ41529.1 - 0.29 11.2 5.2 3.1 7.9 1.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_6 PF14835.6 KXZ41529.1 - 0.31 10.9 2.8 0.19 11.6 0.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF3987 PF13148.6 KXZ41530.1 - 2e-07 30.4 0.2 3.5e-05 23.0 0.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3987) AAA_30 PF13604.6 KXZ41530.1 - 0.075 12.7 0.1 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain SMC_hinge PF06470.13 KXZ41530.1 - 0.091 13.1 0.0 0.4 11.0 0.0 2.1 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain RVT_2 PF07727.14 KXZ41531.1 - 8e-71 238.5 0.0 1.1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KXZ41532.1 - 3.8e-22 78.7 0.0 9.4e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KXZ41532.1 - 1e-08 34.9 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 KXZ41532.1 - 0.00018 21.2 0.0 0.0005 19.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 KXZ41532.1 - 0.0015 18.5 6.4 0.0032 17.5 6.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXZ41532.1 - 0.0039 17.0 5.0 0.0066 16.2 5.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KXZ41532.1 - 0.62 9.8 4.3 1.3 8.9 4.3 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger BACK PF07707.15 KXZ41535.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch ADH_zinc_N PF00107.26 KXZ41535.1 - 0.12 12.4 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Cu2_monoox_C PF03712.15 KXZ41536.1 - 3.2e-34 117.7 0.0 5.2e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KXZ41536.1 - 3.8e-30 104.8 0.0 6e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KXZ41536.1 - 2.3e-11 44.0 0.0 9.9e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 DOMON domain PhyH PF05721.13 KXZ41537.1 - 0.002 18.4 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pkinase PF00069.25 KXZ41538.1 - 1.8e-22 80.0 0.0 4.1e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41538.1 - 1.3e-20 73.7 0.0 2.4e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ41538.1 - 0.003 17.5 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family BSP_II PF05432.11 KXZ41539.1 - 0.058 13.1 23.7 0.068 12.9 23.7 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 KXZ41539.1 - 0.15 11.4 14.4 0.16 11.2 14.4 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KXZ41539.1 - 0.94 8.8 23.1 1.2 8.5 23.1 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXZ41539.1 - 0.95 7.6 19.7 1.2 7.2 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family VIR_N PF15912.5 KXZ41539.1 - 2 7.9 10.1 2.8 7.5 10.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PNTB PF02233.16 KXZ41540.1 - 2.6e-176 587.1 32.6 3.2e-176 586.8 26.3 2.3 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KXZ41540.1 - 5.9e-67 225.1 0.5 2.2e-66 223.2 0.5 2.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KXZ41540.1 - 1.7e-40 138.4 0.0 4.1e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KXZ41540.1 - 2.3e-29 101.7 2.5 2.3e-29 101.7 2.5 3.6 4 0 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 KXZ41540.1 - 0.0022 17.8 4.2 0.0042 16.8 0.4 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.14 KXZ41540.1 - 0.0064 15.8 0.2 0.03 13.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ41540.1 - 0.013 16.1 2.1 0.064 13.8 1.5 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXZ41540.1 - 0.048 13.0 1.1 1.8 7.9 0.2 2.9 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KXZ41540.1 - 0.33 10.9 4.2 0.27 11.2 0.4 2.9 3 0 0 3 3 3 0 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KXZ41540.1 - 3.7 7.9 10.3 2.2 8.6 1.6 3.5 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain MOZ_SAS PF01853.18 KXZ41541.1 - 3.4e-80 267.9 0.0 5.2e-80 267.3 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXZ41541.1 - 4.7e-22 77.4 1.6 4.7e-22 77.4 1.6 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 KXZ41541.1 - 2.8e-14 52.7 0.4 6.6e-14 51.6 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KXZ41541.1 - 0.00065 20.1 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ41541.1 - 0.0099 16.1 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_9 PF00759.19 KXZ41542.1 - 1.9e-17 63.8 0.0 2.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 RWP-RK PF02042.15 KXZ41543.1 - 4e-15 55.5 0.2 6.5e-15 54.8 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 KXZ41543.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family CAP_N PF01213.19 KXZ41543.1 - 2.7 7.4 8.1 0.1 12.0 2.3 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Zn_Tnp_IS1595 PF12760.7 KXZ41544.1 - 0.087 12.8 0.1 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain VirC1 PF07015.11 KXZ41544.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein QSregVF_b PF12843.7 KXZ41547.1 - 0.0094 15.8 0.0 24 4.9 0.0 3.3 3 0 0 3 3 3 3 Putative quorum-sensing-regulated virulence factor eIF3_N PF09440.10 KXZ41548.1 - 1.2e-45 155.3 2.6 1.2e-45 155.3 2.6 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KXZ41548.1 - 2.3e-18 66.6 0.3 2.1e-17 63.6 0.0 2.6 2 1 1 3 3 3 1 PCI domain TPR_19 PF14559.6 KXZ41548.1 - 0.0033 17.9 0.3 0.0082 16.6 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Gp-FAR-1 PF05823.12 KXZ41548.1 - 0.035 14.5 0.7 0.092 13.1 0.1 2.1 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TPR_14 PF13428.6 KXZ41548.1 - 0.043 14.6 0.1 0.16 12.9 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ41548.1 - 0.089 13.0 1.1 0.28 11.5 0.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CPSF73-100_C PF11718.8 KXZ41549.1 - 7.1e-37 127.1 0.0 9.5e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_6 PF16661.5 KXZ41549.1 - 8.5e-18 64.5 0.0 1.5e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KXZ41549.1 - 1.5e-17 64.3 0.1 3.7e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXZ41549.1 - 3.5e-08 33.2 0.7 4.9e-07 29.5 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXZ41549.1 - 0.00041 20.3 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KXZ41549.1 - 0.0032 16.7 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative beta-lactamase-like family Beta-Casp PF10996.8 KXZ41549.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Beta-Casp domain Glyco_hydro_42 PF02449.15 KXZ41551.1 - 1.2e-19 71.0 0.5 1.7e-19 70.4 0.5 1.2 1 0 0 1 1 1 1 Beta-galactosidase HSP70 PF00012.20 KXZ41552.1 - 1.4e-18 66.4 0.0 1.9e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein LEA_2 PF03168.13 KXZ41552.1 - 0.18 12.4 0.4 31 5.2 0.0 3.2 3 0 0 3 3 3 0 Late embryogenesis abundant protein Stealth_CR4 PF17103.5 KXZ41552.1 - 0.21 11.5 3.0 3.7 7.5 0.4 3.1 3 0 0 3 3 3 0 Stealth protein CR4, conserved region 4 AAA_30 PF13604.6 KXZ41553.1 - 7.1e-05 22.6 2.4 0.00028 20.6 2.4 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXZ41553.1 - 0.0016 18.9 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXZ41553.1 - 0.003 17.9 0.4 0.4 11.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 KXZ41553.1 - 0.01 15.9 0.2 0.016 15.3 0.2 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3606 PF12244.8 KXZ41553.1 - 0.085 12.8 0.4 0.99 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) AAA_24 PF13479.6 KXZ41553.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain KdpD PF02702.17 KXZ41553.1 - 0.12 11.8 0.3 0.24 10.9 0.3 1.4 1 1 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain NTPase_1 PF03266.15 KXZ41553.1 - 0.16 11.9 0.1 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 NTPase MIB_HERC2 PF06701.13 KXZ41555.1 - 4.4e-20 71.7 22.0 6.6e-11 42.3 6.5 3.5 3 0 0 3 3 3 3 Mib_herc2 U-box PF04564.15 KXZ41555.1 - 9.4e-18 64.2 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXZ41555.1 - 5.6e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Pkinase_Tyr PF07714.17 KXZ41556.1 - 5.1e-19 68.6 0.0 6.3e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ41556.1 - 2.4e-16 59.9 0.0 2.9e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KXZ41557.1 - 9.8e-08 31.7 0.0 5.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41557.1 - 4.9e-07 29.3 0.0 0.00096 18.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Peptidase_S9 PF00326.21 KXZ41558.1 - 4.4e-07 29.6 0.0 8.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXZ41558.1 - 0.009 15.3 0.0 0.024 13.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KXZ41558.1 - 0.026 14.7 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 KXZ41558.1 - 0.04 13.6 0.0 0.082 12.5 0.0 1.4 2 0 0 2 2 2 0 Putative esterase PBP_sp32 PF07222.12 KXZ41559.1 - 0.095 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pkinase PF00069.25 KXZ41560.1 - 1.9e-13 50.4 0.0 2.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Acetyltransf_1 PF00583.25 KXZ41560.1 - 4.1e-10 39.9 0.0 6.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pkinase_Tyr PF07714.17 KXZ41560.1 - 1.5e-08 34.3 0.0 2.1e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FR47 PF08445.10 KXZ41560.1 - 5.7e-05 23.0 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Pkinase_fungal PF17667.1 KXZ41560.1 - 0.00022 20.1 0.0 0.00033 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Acetyltransf_10 PF13673.7 KXZ41560.1 - 0.00075 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ41560.1 - 0.00089 19.6 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kdo PF06293.14 KXZ41560.1 - 0.058 12.7 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_CG PF14542.6 KXZ41560.1 - 0.083 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CxC4 PF18717.1 KXZ41561.1 - 2.5e-07 30.6 0.2 2.5e-07 30.6 0.2 1.8 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases DUF1266 PF06889.11 KXZ41561.1 - 0.036 14.1 0.2 0.064 13.3 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Metallophos_3 PF14582.6 KXZ41562.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF3043 PF11241.8 KXZ41564.1 - 0.00068 19.7 0.5 0.0013 18.8 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3043) Ctr PF04145.15 KXZ41564.1 - 0.079 13.6 0.2 0.14 12.8 0.2 1.5 1 0 0 1 1 1 0 Ctr copper transporter family DUF2207 PF09972.9 KXZ41564.1 - 0.082 11.7 3.6 0.12 11.2 3.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LMF1 PF06762.14 KXZ41564.1 - 1.3 8.0 3.1 1.7 7.6 3.1 1.1 1 0 0 1 1 1 0 Lipase maturation factor Amnionless PF14828.6 KXZ41564.1 - 3.4 6.4 5.0 6.5 5.5 5.0 1.4 1 0 0 1 1 1 0 Amnionless Glyco_tran_28_C PF04101.16 KXZ41565.1 - 2e-26 93.0 0.0 2.2e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KXZ41565.1 - 0.0017 17.3 0.0 0.0022 16.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DIOX_N PF14226.6 KXZ41566.1 - 1.3e-05 26.0 0.0 1.9e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2786 PF10979.8 KXZ41569.1 - 0.02 14.8 1.3 0.11 12.4 1.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) DUF2757 PF10955.8 KXZ41569.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) RsdA_SigD_bd PF16751.5 KXZ41570.1 - 0.15 12.3 1.6 0.73 10.1 1.6 2.1 1 1 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region DUF2026 PF09641.10 KXZ41570.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) Pkinase PF00069.25 KXZ41572.1 - 3.6e-25 88.8 0.0 6.8e-08 32.2 0.1 3.3 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41572.1 - 3.7e-25 88.7 0.0 4.3e-14 52.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ41572.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Spt20 PF12090.8 KXZ41572.1 - 4.7 6.8 10.3 6.9 6.2 10.3 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 KXZ41572.1 - 6.3 6.7 11.7 9.3 6.1 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCB2_CCB4 PF11152.8 KXZ41573.1 - 1.6e-45 154.8 0.2 1.9e-45 154.6 0.2 1.0 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 Ribosomal_L30_N PF08079.12 KXZ41574.1 - 2.1e-27 95.2 13.4 2.1e-27 95.2 13.4 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KXZ41574.1 - 7.8e-18 64.1 3.7 7.8e-18 64.1 3.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 KXZ41574.1 - 0.089 12.6 1.0 6.1 6.7 0.6 2.2 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter RabGAP-TBC PF00566.18 KXZ41575.1 - 2.4e-23 82.9 1.1 2.8e-23 82.7 1.1 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1731 PF08338.11 KXZ41576.1 - 3.2e-19 68.5 0.1 7.7e-19 67.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 KXZ41576.1 - 2e-15 57.0 0.0 2.6e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXZ41576.1 - 6.9e-10 39.1 0.3 8.2e-10 38.9 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXZ41576.1 - 1.4e-05 24.8 1.0 2.8e-05 23.8 1.0 1.6 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXZ41576.1 - 0.00053 19.5 0.1 0.041 13.3 0.0 2.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXZ41576.1 - 0.001 18.3 0.2 0.02 14.0 0.2 2.4 3 0 0 3 3 3 1 Male sterility protein RmlD_sub_bind PF04321.17 KXZ41576.1 - 0.019 14.0 0.2 0.032 13.3 0.2 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXZ41576.1 - 0.037 13.1 0.0 5.8 6.0 0.1 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KXZ41576.1 - 0.095 13.1 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KXZ41576.1 - 0.16 11.4 0.7 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase tRNA_edit PF04073.15 KXZ41582.1 - 0.077 13.1 0.5 0.15 12.2 0.5 1.5 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain UCH PF00443.29 KXZ41584.1 - 6.5e-28 97.9 0.0 8.3e-27 94.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ41584.1 - 1.4e-05 24.8 0.1 0.3 10.6 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 KXZ41584.1 - 0.0058 16.5 16.6 0.17 11.8 1.2 4.1 3 0 0 3 3 3 2 Ubiquitin interaction motif AAA_16 PF13191.6 KXZ41585.1 - 0.0011 19.4 1.1 0.0011 19.4 1.1 4.1 4 1 0 4 4 4 1 AAA ATPase domain Helitron_like_N PF14214.6 KXZ41585.1 - 0.025 14.8 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus AAA_21 PF13304.6 KXZ41585.1 - 0.047 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ribo_biogen_C PF04034.13 KXZ41585.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal Phage_Orf51 PF06194.11 KXZ41585.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 ZZ PF00569.17 KXZ41587.1 - 4.7e-07 29.5 0.1 1.4e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-RING_2 PF13639.6 KXZ41587.1 - 2.2e-05 24.7 4.7 2.2e-05 24.7 4.7 1.9 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 KXZ41587.1 - 0.0007 19.4 4.9 0.0019 18.0 4.9 1.8 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 KXZ41587.1 - 0.077 13.0 2.3 0.22 11.6 2.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXZ41587.1 - 0.12 12.4 1.9 0.31 11.1 1.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KXZ41587.1 - 0.23 11.7 3.4 0.55 10.4 3.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.7 KXZ41587.1 - 0.35 11.2 3.3 1 9.7 3.3 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KXZ41587.1 - 0.65 9.8 3.3 1.5 8.7 3.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KXZ41587.1 - 5 7.3 5.9 11 6.3 5.9 1.6 1 0 0 1 1 1 0 RING-variant domain SUIM_assoc PF16619.5 KXZ41587.1 - 10 6.3 7.3 28 4.9 7.3 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NDUF_B7 PF05676.13 KXZ41588.1 - 6.5e-24 83.4 7.4 8.1e-24 83.1 7.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KXZ41588.1 - 9.8e-05 22.3 2.3 0.00014 21.8 2.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KXZ41588.1 - 0.18 11.9 3.5 0.38 10.8 3.4 1.6 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KXZ41588.1 - 1.4 9.2 8.5 4 7.8 1.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Na_H_Exchanger PF00999.21 KXZ41589.1 - 3.4e-15 55.7 30.4 2.8e-14 52.7 30.4 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family LPAM_1 PF08139.12 KXZ41590.1 - 0.19 12.3 1.7 0.64 10.6 1.7 2.0 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SHS2_Rpb7-N PF03876.17 KXZ41592.1 - 2.5e-15 56.6 0.0 6.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KXZ41592.1 - 1.2e-10 41.5 0.0 2.2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNase_II_C_S1 PF18614.1 KXZ41592.1 - 0.026 14.5 0.1 4 7.5 0.0 2.4 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain RNA_pol_Rbc25 PF08292.12 KXZ41592.1 - 0.047 13.9 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 TPR_14 PF13428.6 KXZ41593.1 - 0.0055 17.4 2.4 0.0055 17.4 2.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ41593.1 - 0.21 11.8 0.3 0.21 11.8 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PIN_3 PF13470.6 KXZ41593.1 - 6.5 7.6 9.9 0.43 11.4 2.6 2.1 1 1 1 2 2 2 0 PIN domain Pkinase PF00069.25 KXZ41594.1 - 1.4e-70 237.7 0.0 1.7e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41594.1 - 2.2e-47 161.5 0.0 3e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ41594.1 - 1.1e-05 24.9 0.0 0.0034 16.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KXZ41594.1 - 2.6e-05 23.2 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ41594.1 - 0.0027 17.1 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ41594.1 - 0.0082 16.1 0.1 0.048 13.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXZ41594.1 - 0.045 13.3 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KXZ41594.1 - 0.05 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Mito_fiss_reg PF05308.11 KXZ41595.1 - 1.1 9.3 3.5 1.8 8.6 3.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXZ41595.1 - 1.3 8.4 9.4 2 7.8 9.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal His_biosynth PF00977.21 KXZ41596.1 - 4.5e-31 108.1 1.8 7.6e-18 64.8 0.5 2.9 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 KXZ41596.1 - 9.2e-20 71.2 0.0 1.4e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KXZ41596.1 - 2.6e-08 33.7 0.0 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KXZ41596.1 - 3.9e-08 33.4 0.0 1.2e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 KXZ41596.1 - 0.0069 16.2 0.1 0.85 9.3 0.1 2.3 2 0 0 2 2 2 2 Peptidase C26 GATase_5 PF13507.6 KXZ41596.1 - 0.2 10.8 0.0 0.54 9.3 0.0 1.7 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ATP-synt_B PF00430.18 KXZ41597.1 - 9e-15 54.9 0.1 9e-15 54.9 0.1 1.7 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) Mt_ATP-synt_B PF05405.14 KXZ41597.1 - 2.9e-05 23.7 0.2 5.3e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF948 PF06103.11 KXZ41597.1 - 0.00074 19.7 0.7 0.035 14.3 0.1 2.6 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) TarH PF02203.15 KXZ41597.1 - 0.0017 18.3 0.3 0.0017 18.3 0.3 1.9 2 0 0 2 2 2 1 Tar ligand binding domain homologue HrpE PF06188.12 KXZ41597.1 - 0.0098 15.8 0.2 0.02 14.8 0.2 1.5 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E RapA_C PF12137.8 KXZ41597.1 - 0.034 13.2 0.2 0.037 13.1 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal CCDC142 PF14923.6 KXZ41597.1 - 0.037 12.8 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil protein 142 SEO_N PF14576.6 KXZ41597.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion N-terminus CAP_N PF01213.19 KXZ41597.1 - 0.1 12.1 1.2 1.8 8.0 0.1 2.0 1 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal V-ATPase_G_2 PF16999.5 KXZ41597.1 - 0.42 11.1 10.7 0.031 14.7 3.2 2.5 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Bax1-I PF01027.20 KXZ41598.1 - 0.18 11.6 4.0 0.22 11.3 3.3 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KXZ41598.1 - 1 8.9 4.1 1.4 8.4 4.1 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Ank_2 PF12796.7 KXZ41601.1 - 4e-63 210.0 16.2 7.3e-21 74.6 0.8 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41601.1 - 1.6e-54 181.6 1.6 1.5e-12 47.7 0.1 5.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41601.1 - 8.4e-53 174.6 13.4 8.9e-07 29.1 0.0 9.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 KXZ41601.1 - 9.1e-48 154.7 4.3 2.4e-05 24.4 0.0 9.2 10 0 0 10 10 9 8 Ankyrin repeat Ank_5 PF13857.6 KXZ41601.1 - 9.6e-42 140.5 13.0 1.3e-09 38.1 0.3 7.8 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Pkinase PF00069.25 KXZ41601.1 - 2.2e-28 99.4 0.0 3.2e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41601.1 - 7e-17 61.6 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ41601.1 - 0.019 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KXZ41601.1 - 0.028 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RVP PF00077.20 KXZ41601.1 - 0.076 13.3 0.9 2.4 8.5 0.0 3.5 4 1 1 5 5 4 0 Retroviral aspartyl protease DUF3404 PF11884.8 KXZ41601.1 - 0.57 9.3 2.1 2.9 7.0 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3404) DUF3739 PF12545.8 KXZ41601.1 - 1.6 9.2 6.3 15 6.1 0.2 3.0 3 0 0 3 3 3 0 Filamentous haemagglutinin family outer membrane protein Calponin PF00402.18 KXZ41601.1 - 2.5 7.8 7.1 18 5.1 0.4 3.9 4 0 0 4 4 4 0 Calponin family repeat RVT_2 PF07727.14 KXZ41602.1 - 5.6e-75 252.1 0.0 8.2e-41 140.2 0.0 3.4 1 1 2 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KXZ41602.1 - 3e-16 59.7 0.0 1.6e-15 57.4 0.0 2.3 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 KXZ41602.1 - 6.1e-16 58.3 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KXZ41602.1 - 1.4e-09 37.6 0.0 3.7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 KXZ41602.1 - 0.0012 18.6 0.0 0.0057 16.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 KXZ41602.1 - 0.0013 18.7 0.3 0.0039 17.2 0.3 1.9 1 0 0 1 1 1 1 Zinc knuckle Ank_2 PF12796.7 KXZ41606.1 - 1.5e-41 140.8 4.4 8.8e-17 61.5 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ41606.1 - 1.4e-29 101.7 4.0 6.5e-12 45.5 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41606.1 - 3.5e-27 93.6 7.5 7.9e-07 29.3 0.0 7.1 7 0 0 7 7 6 4 Ankyrin repeat Ank_4 PF13637.6 KXZ41606.1 - 1.9e-26 92.1 0.2 1.6e-10 41.3 0.0 4.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) COR PF16095.5 KXZ41606.1 - 3.2e-22 79.3 0.0 5.6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_3 PF13606.6 KXZ41606.1 - 1.2e-21 74.5 0.5 0.00087 19.6 0.0 6.6 7 0 0 7 7 5 4 Ankyrin repeat Roc PF08477.13 KXZ41606.1 - 1.1e-16 61.1 0.0 2e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ41606.1 - 1.1e-07 31.6 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ41606.1 - 0.00033 20.1 0.0 0.00077 19.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Mg_chelatase PF01078.21 KXZ41606.1 - 0.0054 16.1 0.8 0.0098 15.3 0.2 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ41606.1 - 0.037 14.4 4.4 0.29 11.5 0.5 3.4 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KXZ41606.1 - 0.055 13.8 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2384 PF09722.10 KXZ41606.1 - 0.067 13.2 7.4 2.4 8.3 0.0 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF2384) AAA_28 PF13521.6 KXZ41606.1 - 0.088 13.0 0.6 14 5.9 0.1 2.8 2 0 0 2 2 2 0 AAA domain RNA_POL_M_15KD PF02150.16 KXZ41606.1 - 0.11 12.4 0.3 0.9 9.5 0.0 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit AAA_33 PF13671.6 KXZ41606.1 - 0.12 12.5 0.1 0.64 10.2 0.1 2.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ41606.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KXZ41606.1 - 0.17 11.8 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KXZ41606.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran_CTD PF16326.5 KXZ41608.1 - 0.0055 16.9 7.9 0.03 14.5 7.9 2.3 1 0 0 1 1 1 1 ABC transporter C-terminal domain FapA PF03961.13 KXZ41608.1 - 0.024 13.2 0.9 0.035 12.7 0.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tropomyosin_1 PF12718.7 KXZ41608.1 - 0.029 14.5 9.1 0.057 13.6 9.1 1.4 1 0 0 1 1 1 0 Tropomyosin like CCDC-167 PF15188.6 KXZ41608.1 - 0.036 14.4 9.6 0.09 13.1 9.6 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4209 PF13910.6 KXZ41608.1 - 0.049 13.9 0.0 17 5.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4209) AAA_22 PF13401.6 KXZ41608.1 - 0.13 12.6 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain FliJ PF02050.16 KXZ41608.1 - 0.13 12.5 6.0 0.44 10.8 6.0 2.0 1 0 0 1 1 1 0 Flagellar FliJ protein FlxA PF14282.6 KXZ41608.1 - 0.37 10.8 6.5 1.2 9.2 6.5 1.9 1 0 0 1 1 1 0 FlxA-like protein Sec34 PF04136.15 KXZ41608.1 - 0.79 9.6 4.0 34 4.3 0.0 2.7 2 0 0 2 2 2 0 Sec34-like family DUF3584 PF12128.8 KXZ41608.1 - 3.2 5.1 7.0 0.46 7.9 3.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 KXZ41608.1 - 9.4 6.5 12.6 4.2 7.6 9.7 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SelK_SelG PF10961.8 KXZ41609.1 - 6.9 7.4 5.5 4.4 8.0 1.1 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Cyclin_N PF00134.23 KXZ41610.1 - 1.1e-07 31.7 0.0 7.7e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain EPF PF17181.4 KXZ41610.1 - 0.0012 18.8 2.1 0.0029 17.6 2.1 1.6 1 0 0 1 1 1 1 Epidermal patterning factor proteins Cyclin_C PF02984.19 KXZ41610.1 - 0.093 12.8 0.6 0.16 12.1 0.6 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain Peptidase_M48 PF01435.18 KXZ41612.1 - 3.7e-16 59.5 7.0 2.8e-15 56.6 7.0 1.9 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M78 PF06114.13 KXZ41612.1 - 0.0016 18.4 0.5 0.0037 17.2 0.2 1.7 2 1 0 2 2 2 1 IrrE N-terminal-like domain DUF45 PF01863.17 KXZ41612.1 - 1.4 8.9 6.3 0.58 10.2 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 Peptidase_U49 PF10463.9 KXZ41612.1 - 4.5 7.0 4.9 66 3.2 4.9 2.4 1 1 0 1 1 1 0 Peptidase U49 Peptidase_M48 PF01435.18 KXZ41613.1 - 6.5e-09 35.8 0.2 1e-08 35.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M48 MscS_porin PF12795.7 KXZ41614.1 - 0.0015 18.1 36.3 0.0015 18.1 36.3 2.8 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 KXZ41614.1 - 0.025 14.7 1.6 0.025 14.7 1.6 4.6 3 1 1 4 4 4 0 TolA binding protein trimerisation DUF1664 PF07889.12 KXZ41614.1 - 0.14 12.2 11.5 1.5 8.9 1.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KXZ41614.1 - 0.34 11.4 7.2 31 5.1 0.0 4.1 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KXZ41614.1 - 0.44 9.4 52.2 0.017 14.0 13.7 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.11 KXZ41614.1 - 0.72 10.0 67.9 0.35 11.1 26.5 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Hormone_1 PF00103.20 KXZ41614.1 - 0.72 9.6 4.3 0.23 11.2 1.0 1.8 2 0 0 2 2 2 0 Somatotropin hormone family Atg14 PF10186.9 KXZ41614.1 - 1.3 8.0 37.1 0.036 13.2 19.1 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KXZ41614.1 - 1.7 8.8 9.3 3.6 7.8 0.8 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Vps51 PF08700.11 KXZ41614.1 - 3.8 7.7 8.0 0.61 10.2 0.5 3.1 3 1 0 3 3 3 0 Vps51/Vps67 Tropomyosin_1 PF12718.7 KXZ41614.1 - 4.5 7.4 51.8 0.16 12.1 23.6 3.6 1 1 1 2 2 2 0 Tropomyosin like Vps54_N PF10475.9 KXZ41614.1 - 5.1 6.3 7.5 0.49 9.6 1.3 2.0 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF812 PF05667.11 KXZ41614.1 - 7.3 5.3 34.9 13 4.5 34.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-K PF11802.8 KXZ41614.1 - 7.5 6.0 15.9 2.7 7.5 2.4 2.2 2 0 0 2 2 2 0 Centromere-associated protein K Transposase_24 PF03004.14 KXZ41614.1 - 8.6 6.5 11.8 4.6 7.3 5.0 2.4 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) ATP-synt_DE_N PF02823.16 KXZ41615.1 - 3.3e-16 58.9 0.0 5.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ank PF00023.30 KXZ41616.1 - 9.3e-31 104.9 9.5 3.5e-07 30.4 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KXZ41616.1 - 1.2e-27 96.2 4.0 5.4e-14 52.5 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41616.1 - 2.1e-26 89.1 0.7 9.7e-06 25.6 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ41616.1 - 1.8e-24 85.8 4.8 2.5e-07 31.1 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41616.1 - 7.6e-23 80.3 6.5 1.4e-08 34.8 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ser_hydrolase PF06821.13 KXZ41616.1 - 0.26 11.1 2.9 16 5.3 0.2 2.9 1 1 2 3 3 3 0 Serine hydrolase YppF PF14178.6 KXZ41616.1 - 0.27 11.1 0.7 31 4.5 0.1 2.5 2 0 0 2 2 2 0 YppF-like protein Calponin PF00402.18 KXZ41616.1 - 0.64 9.7 4.1 31 4.3 0.1 3.2 3 0 0 3 3 3 0 Calponin family repeat COG4 PF08318.12 KXZ41619.1 - 2e-63 214.5 0.0 2.8e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Ank_2 PF12796.7 KXZ41619.1 - 6e-12 46.0 0.7 1.9e-07 31.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41619.1 - 1.1e-05 25.8 1.5 0.011 16.3 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41619.1 - 0.0017 18.7 2.9 20 6.2 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KXZ41619.1 - 0.22 11.9 5.2 25 5.4 0.4 4.3 1 1 4 5 5 5 0 Ankyrin repeats (many copies) fn2 PF00040.19 KXZ41621.1 - 1.9e-08 34.4 4.5 0.0084 16.4 0.0 4.5 4 0 0 4 4 4 3 Fibronectin type II domain PEPCK_ATP PF01293.20 KXZ41622.1 - 4.9e-56 190.3 0.0 5.8e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase His_Phos_2 PF00328.22 KXZ41623.1 - 8.9e-08 31.9 0.0 4.3e-07 29.6 0.0 2.2 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) DUF1970 PF09301.10 KXZ41623.1 - 0.064 13.5 2.4 0.17 12.1 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1970) LPAM_1 PF08139.12 KXZ41623.1 - 0.069 13.7 0.8 0.069 13.7 0.8 3.0 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Ribosomal_S10 PF00338.22 KXZ41624.1 - 0.035 14.3 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e UPF0061 PF02696.14 KXZ41625.1 - 7.9e-41 140.3 0.0 8.5e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family rve PF00665.26 KXZ41627.1 - 1e-16 61.2 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KXZ41627.1 - 4.9e-12 45.5 0.0 8.5e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 KXZ41627.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 KXZ41627.1 - 0.00029 20.8 7.4 0.00079 19.4 7.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXZ41627.1 - 0.0058 16.4 5.3 0.012 15.4 5.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KXZ41627.1 - 0.077 12.7 4.9 0.18 11.6 4.9 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger Herpes_capsid PF06112.11 KXZ41628.1 - 4.8 7.2 13.4 8.1 6.5 13.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TCR PF03638.15 KXZ41629.1 - 4.4e-11 42.9 18.9 6.3e-11 42.4 18.9 1.2 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain Methyltransf_25 PF13649.6 KXZ41629.1 - 0.015 16.0 0.0 0.35 11.6 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain E1-E2_ATPase PF00122.20 KXZ41630.1 - 7.5e-25 87.5 8.6 1.5e-18 66.9 0.1 3.1 2 1 1 3 3 3 3 E1-E2 ATPase Cation_ATPase_N PF00690.26 KXZ41630.1 - 6.8e-20 70.5 0.0 1.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF3931 PF13082.6 KXZ41631.1 - 0.2 11.9 0.3 0.74 10.0 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3931) TRAP_alpha PF03896.16 KXZ41634.1 - 0.18 11.0 4.7 0.052 12.8 0.4 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.10 KXZ41634.1 - 6.9 7.1 11.1 7.5 7.0 2.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.12 KXZ41634.1 - 7.7 6.0 8.2 0.14 11.7 0.3 1.9 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DOT1 PF08123.13 KXZ41635.1 - 0.059 12.9 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 ImpA_N PF06812.12 KXZ41635.1 - 0.24 11.5 0.3 21 5.3 0.1 2.3 1 1 1 2 2 2 0 ImpA, N-terminal, type VI secretion system Ank_2 PF12796.7 KXZ41636.1 - 3.9e-57 190.8 0.0 4.2e-14 52.9 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ41636.1 - 2.4e-53 177.5 6.8 1.2e-08 35.1 0.1 9.3 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41636.1 - 3.3e-49 163.3 7.2 5.3e-06 26.6 0.1 9.4 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 KXZ41636.1 - 5e-43 140.1 3.7 7.7e-05 22.8 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KXZ41636.1 - 3.7e-42 142.2 0.3 6.2e-10 39.4 0.1 7.3 4 3 3 7 7 7 7 Ankyrin repeats (many copies) DUF5011 PF16403.5 KXZ41637.1 - 6.3e-20 71.1 1.2 2.8e-05 24.2 0.0 6.2 7 0 0 7 7 7 4 Domain of unknown function (DUF5011) PKD_channel PF08016.12 KXZ41637.1 - 0.17 10.5 7.9 3.2 6.3 8.1 2.1 2 0 0 2 2 2 0 Polycystin cation channel Ion_trans PF00520.31 KXZ41637.1 - 0.35 10.0 7.0 0.75 9.0 7.0 1.5 1 0 0 1 1 1 0 Ion transport protein RNase_PH_C PF03725.15 KXZ41639.1 - 3.8e-07 30.0 0.0 8.9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF812 PF05667.11 KXZ41639.1 - 0.095 11.6 24.1 0.14 11.1 24.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 KXZ41639.1 - 0.31 10.5 32.5 0.46 9.9 32.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HOOK PF05622.12 KXZ41639.1 - 0.61 8.2 27.6 0.89 7.6 27.6 1.1 1 0 0 1 1 1 0 HOOK protein Tmemb_cc2 PF10267.9 KXZ41639.1 - 0.94 8.6 28.3 2.2 7.3 28.3 1.6 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2151 PF10221.9 KXZ41639.1 - 0.95 8.0 10.1 1.3 7.5 10.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Exonuc_VII_L PF02601.15 KXZ41639.1 - 1.5 8.3 19.3 2.2 7.8 19.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 KXZ41639.1 - 1.6 6.6 12.1 2.4 6.0 12.1 1.2 1 0 0 1 1 1 0 Prominin Phage_tail_NK PF16532.5 KXZ41639.1 - 1.7 8.3 3.9 6.8 6.3 0.5 2.3 1 1 1 2 2 2 0 Sf6-type phage tail needle knob or tip of some Caudovirales DDHD PF02862.17 KXZ41639.1 - 1.7 8.8 6.0 3 7.9 6.0 1.4 1 0 0 1 1 1 0 DDHD domain GREB1 PF15782.5 KXZ41639.1 - 2.2 5.3 8.4 2.9 4.9 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP_central PF04928.17 KXZ41639.1 - 2.3 7.1 7.5 3.4 6.6 7.5 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain SID-1_RNA_chan PF13965.6 KXZ41639.1 - 2.6 6.3 7.5 3.6 5.9 7.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3584 PF12128.8 KXZ41639.1 - 2.7 5.4 30.3 3.8 4.9 30.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4776 PF16003.5 KXZ41639.1 - 2.7 6.9 14.5 4.5 6.2 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Gp58 PF07902.11 KXZ41639.1 - 4.7 5.4 6.4 6.6 4.9 6.4 1.2 1 0 0 1 1 1 0 gp58-like protein FapA PF03961.13 KXZ41639.1 - 4.8 5.7 17.0 7.8 5.0 17.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_23 PF13476.6 KXZ41639.1 - 5.1 7.5 21.1 9.9 6.6 21.1 1.5 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 KXZ41639.1 - 5.6 5.4 10.5 8.9 4.7 10.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prefoldin_2 PF01920.20 KXZ41639.1 - 7.8 6.5 35.0 5.5 7.0 15.6 3.1 1 1 2 3 3 3 0 Prefoldin subunit Phage_GPO PF05929.11 KXZ41639.1 - 8 6.0 18.5 13 5.3 18.5 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Presenilin PF01080.17 KXZ41639.1 - 9.9 4.8 14.5 15 4.2 14.5 1.3 1 0 0 1 1 1 0 Presenilin Roc PF08477.13 KXZ41640.1 - 3.2e-18 66.1 0.0 4.7e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 KXZ41640.1 - 3.1e-12 46.9 0.0 8.1e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ41640.1 - 4.9e-11 42.5 0.2 4.4e-06 26.9 0.0 3.8 3 1 1 4 4 3 2 Ankyrin repeat Ank_5 PF13857.6 KXZ41640.1 - 1e-09 38.5 0.0 3e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ras PF00071.22 KXZ41640.1 - 5.5e-08 32.6 0.0 7.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Ank_3 PF13606.6 KXZ41640.1 - 2.1e-07 30.7 0.0 0.00025 21.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Arf PF00025.21 KXZ41640.1 - 1.4e-06 27.9 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_4 PF13637.6 KXZ41640.1 - 3.7e-06 27.4 0.0 0.00032 21.2 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Mg_chelatase PF01078.21 KXZ41640.1 - 0.00052 19.4 0.1 0.00076 18.9 0.1 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Gtr1_RagA PF04670.12 KXZ41640.1 - 0.0073 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KXZ41640.1 - 0.0086 16.3 0.1 0.017 15.4 0.1 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ41640.1 - 0.012 15.9 0.2 0.02 15.3 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KXZ41640.1 - 0.014 15.0 1.4 0.036 13.6 0.4 2.0 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 KXZ41640.1 - 0.018 15.2 0.0 0.05 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXZ41640.1 - 0.026 15.0 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KXZ41640.1 - 0.062 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KXZ41640.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 KXZ41640.1 - 0.099 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 KXZ41640.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXZ41640.1 - 0.25 10.5 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 KXZ41641.1 - 3.3e-18 66.0 0.0 9.8e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ41641.1 - 6.3e-18 65.3 0.0 8.9e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 KXZ41641.1 - 9.4e-09 35.1 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ41641.1 - 7.6e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_2 PF12796.7 KXZ41641.1 - 3.9e-05 24.1 0.1 0.00017 22.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41641.1 - 0.00019 21.6 0.0 0.0013 19.1 0.0 2.5 2 0 0 2 2 1 1 Ankyrin repeat Ank PF00023.30 KXZ41641.1 - 0.00062 20.1 0.1 0.0034 17.7 0.0 2.3 3 0 0 3 3 2 1 Ankyrin repeat AAA_16 PF13191.6 KXZ41641.1 - 0.0094 16.3 0.4 0.2 12.0 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain Ank_4 PF13637.6 KXZ41641.1 - 0.069 13.7 0.0 0.41 11.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41641.1 - 0.12 12.7 0.1 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_22 PF13401.6 KXZ41641.1 - 0.19 12.0 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KXZ41641.1 - 0.25 10.7 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FUSC_2 PF13515.6 KXZ41642.1 - 0.0023 18.1 10.6 0.0023 18.1 10.6 3.6 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KXZ41642.1 - 1 8.1 4.1 21 3.8 0.0 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Peptidase_A2E PF12382.8 KXZ41643.1 - 0.0021 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon peptidase TPT PF03151.16 KXZ41644.1 - 2.2e-13 50.2 7.4 8.6e-13 48.3 7.4 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family Acyl-CoA_dh_2 PF08028.11 KXZ41644.1 - 0.024 14.9 1.0 0.055 13.7 1.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain EamA PF00892.20 KXZ41644.1 - 0.65 10.2 25.5 1 9.5 6.9 2.9 3 1 0 3 3 3 0 EamA-like transporter family Ribosomal_L3 PF00297.22 KXZ41646.1 - 4.1e-22 78.7 4.3 2.1e-19 69.8 2.5 2.6 2 1 1 3 3 3 2 Ribosomal protein L3 DUF3482 PF11981.8 KXZ41647.1 - 0.043 13.2 1.4 0.069 12.5 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3482) HDPD PF02924.14 KXZ41647.1 - 0.86 9.7 8.8 1.2 9.3 8.8 1.2 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D Chromo PF00385.24 KXZ41650.1 - 1e-12 47.7 0.7 2.8e-12 46.4 0.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 KXZ41650.1 - 8.9e-08 32.3 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain YlbD_coat PF14071.6 KXZ41650.1 - 0.063 13.5 0.3 0.77 10.0 0.2 2.3 2 0 0 2 2 2 0 Putative coat protein STI1 PF17830.1 KXZ41651.1 - 0.019 14.9 0.3 0.04 13.9 0.3 1.5 1 0 0 1 1 1 0 STI1 domain DSBA PF01323.20 KXZ41652.1 - 0.0028 17.4 0.1 0.0094 15.8 0.1 1.8 1 1 1 2 2 2 1 DSBA-like thioredoxin domain HLH PF00010.26 KXZ41653.1 - 1.7e-11 43.9 0.2 3.3e-11 42.9 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_2 PF07716.15 KXZ41653.1 - 1 9.5 9.6 0.44 10.7 2.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper IFT46_B_C PF12317.8 KXZ41654.1 - 1.7e-90 302.4 0.1 2.1e-90 302.1 0.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Pkinase PF00069.25 KXZ41657.1 - 2.9e-29 102.2 0.0 1.5e-26 93.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41657.1 - 3e-29 102.1 0.0 2.5e-26 92.5 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 KXZ41657.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Roc PF08477.13 KXZ41658.1 - 1.8e-17 63.7 0.0 2.9e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ41658.1 - 3.6e-08 33.0 0.0 5.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXZ41658.1 - 3.8e-08 33.1 0.0 5.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 KXZ41658.1 - 4.1e-08 33.7 0.0 6.4e-07 29.9 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ41658.1 - 8.9e-08 32.3 0.0 2.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41658.1 - 1.7e-07 31.4 0.1 6.4e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KXZ41658.1 - 0.00029 21.1 0.0 0.0065 16.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Mg_chelatase PF01078.21 KXZ41658.1 - 0.00048 19.6 0.1 0.00076 18.9 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KXZ41658.1 - 0.0049 17.2 0.1 0.0087 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ41658.1 - 0.022 15.1 0.1 0.039 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KXZ41658.1 - 0.026 14.1 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXZ41658.1 - 0.027 14.4 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Ank_4 PF13637.6 KXZ41658.1 - 0.027 15.0 0.0 0.55 10.9 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) ABC_tran PF00005.27 KXZ41658.1 - 0.046 14.2 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KXZ41658.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_PrkA PF08298.11 KXZ41658.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Gtr1_RagA PF04670.12 KXZ41658.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 KXZ41658.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXZ41658.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KXZ41658.1 - 0.15 11.8 0.1 0.91 9.3 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KXZ41658.1 - 0.19 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Helicase_C PF00271.31 KXZ41659.1 - 1.3e-22 80.3 0.0 2.6e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Metallophos PF00149.28 KXZ41660.1 - 2.4e-07 31.5 0.2 0.0027 18.2 0.0 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ41660.1 - 0.00012 22.3 0.3 0.0015 18.7 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain AF-4 PF05110.13 KXZ41660.1 - 0.055 11.6 19.7 0.087 10.9 19.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SelP_N PF04592.14 KXZ41660.1 - 3.1 7.1 18.0 0.13 11.7 8.0 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF515 PF04415.12 KXZ41660.1 - 7.8 4.8 8.6 11 4.3 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SRP40_C PF05022.12 KXZ41661.1 - 2.4e-23 82.8 2.7 2.4e-23 82.8 2.7 5.8 6 1 0 6 6 6 1 SRP40, C-terminal domain BTB PF00651.31 KXZ41663.1 - 0.0057 16.9 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain gag-asp_proteas PF13975.6 KXZ41664.1 - 0.23 12.1 0.0 0.63 10.6 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease CENP-B_dimeris PF09026.10 KXZ41665.1 - 8.1 6.9 12.5 5.4 7.5 2.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DOT1 PF08123.13 KXZ41666.1 - 0.061 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 BACK PF07707.15 KXZ41669.1 - 0.019 15.1 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 BTB And C-terminal Kelch Ank_2 PF12796.7 KXZ41670.1 - 6.6e-23 81.1 0.2 5.7e-15 55.7 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41670.1 - 3e-22 78.7 1.2 2.4e-12 47.1 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41670.1 - 3.8e-21 72.9 0.0 4.6e-05 23.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KXZ41670.1 - 5.9e-19 67.6 0.2 8.3e-06 26.0 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ41670.1 - 1.7e-15 56.8 0.3 1e-07 32.0 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ41670.1 - 0.16 11.7 0.3 20 5.0 0.0 3.3 3 0 0 3 3 3 0 Calponin family repeat DUF4473 PF14747.6 KXZ41670.1 - 9.6 6.8 6.9 61 4.3 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) PhoLip_ATPase_C PF16212.5 KXZ41671.1 - 1.6e-74 250.8 25.6 1.6e-74 250.8 25.6 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXZ41671.1 - 4.4e-19 67.9 0.9 1.1e-18 66.6 0.9 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXZ41671.1 - 8.5e-14 52.3 0.2 5e-06 27.0 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ41671.1 - 9.3e-12 44.9 0.1 4.1e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXZ41671.1 - 2.1e-07 30.6 0.0 6.9e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXZ41671.1 - 0.00048 20.0 0.1 0.0017 18.2 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 KXZ41673.1 - 2.2e-58 194.8 3.1 1.5e-16 60.7 0.2 6.2 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41673.1 - 7.8e-52 173.0 9.8 6e-09 36.3 0.1 7.6 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41673.1 - 4.2e-44 147.1 22.9 8.5e-07 29.2 0.1 11.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 KXZ41673.1 - 1.8e-43 146.0 18.0 3e-12 46.5 1.1 8.0 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41673.1 - 2.8e-41 134.8 11.8 1.8e-05 24.7 0.0 11.0 10 0 0 10 10 10 7 Ankyrin repeat UbiA PF01040.18 KXZ41674.1 - 3.3e-51 174.0 25.5 4.1e-51 173.7 25.5 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family YTH PF04146.15 KXZ41675.1 - 9.9e-38 129.7 0.0 3.6e-37 127.9 0.0 1.9 1 1 0 1 1 1 1 YT521-B-like domain Hexapep PF00132.24 KXZ41676.1 - 7.9e-16 57.1 14.9 5.3e-08 32.3 2.7 4.0 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ41676.1 - 1.2e-07 31.4 13.8 6.1e-05 22.7 3.7 3.7 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXZ41676.1 - 0.028 13.4 0.3 0.33 9.8 0.2 1.9 1 1 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 KXZ41676.1 - 0.13 10.4 0.7 0.17 10.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) NUDIX PF00293.28 KXZ41677.1 - 2.2e-14 53.6 0.0 3.9e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain EAP30 PF04157.16 KXZ41680.1 - 5.4e-73 245.2 0.0 6.6e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DprA_WH PF17782.1 KXZ41680.1 - 0.036 14.2 0.1 9.1 6.5 0.0 2.4 2 0 0 2 2 2 0 DprA winged helix domain HTH_IclR PF09339.10 KXZ41680.1 - 0.046 13.5 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Kelch_6 PF13964.6 KXZ41681.1 - 4.7e-06 26.7 0.0 0.1 12.9 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 KXZ41681.1 - 0.0012 18.7 0.0 0.055 13.5 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 KXZ41681.1 - 0.0027 17.7 0.0 1.7 8.7 0.0 2.9 2 0 0 2 2 2 2 Galactose oxidase, central domain DNA_pol_phi PF04931.13 KXZ41682.1 - 6.3e-07 27.9 0.4 7.7e-07 27.6 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF3243 PF11588.8 KXZ41682.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3243) SBP PF03110.14 KXZ41683.1 - 6.4e-30 103.3 12.2 1.1e-29 102.6 12.2 1.4 1 0 0 1 1 1 1 SBP domain BTB PF00651.31 KXZ41683.1 - 4e-08 33.5 0.0 8.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 KXZ41684.1 - 1.3e-24 86.6 1.3 7.7e-06 26.4 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41684.1 - 4.4e-18 65.4 8.7 0.00069 20.1 0.0 6.6 4 4 2 7 7 7 5 Ankyrin repeats (many copies) Ion_trans PF00520.31 KXZ41684.1 - 3e-17 62.7 10.0 4.3e-17 62.2 10.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_5 PF13857.6 KXZ41684.1 - 2.8e-13 49.8 10.9 0.00031 21.0 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41684.1 - 9.2e-09 34.9 13.6 0.85 10.4 0.0 9.3 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 KXZ41684.1 - 5.9e-08 32.8 10.8 0.73 10.4 0.0 7.7 8 0 0 8 8 8 2 Ankyrin repeat Ion_trans_2 PF07885.16 KXZ41684.1 - 0.0037 17.2 1.1 0.0037 17.2 1.1 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KXZ41684.1 - 0.016 15.3 0.0 5.8 7.1 0.0 2.9 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain ATC_hydrolase PF14196.6 KXZ41685.1 - 6.4e-06 27.0 0.0 7.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase Rhodanese PF00581.20 KXZ41689.1 - 1.3e-15 57.8 0.0 5e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain CAP_N PF01213.19 KXZ41690.1 - 0.0011 18.6 3.8 0.0011 18.6 3.8 2.3 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal MSA-2c PF12238.8 KXZ41690.1 - 9.3 6.2 11.7 0.23 11.4 5.0 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c K_trans PF02705.16 KXZ41691.1 - 3.4e-181 603.4 4.7 5.1e-181 602.8 4.7 1.2 1 1 0 1 1 1 1 K+ potassium transporter Sporozoite_P67 PF05642.11 KXZ41691.1 - 2.5 6.1 8.3 5.1 5.1 8.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4743 PF15916.5 KXZ41694.1 - 0.27 11.2 1.0 21 5.1 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4743) AAA_19 PF13245.6 KXZ41695.1 - 0.0054 17.1 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KXZ41695.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KXZ41695.1 - 0.035 14.5 0.1 0.2 12.1 0.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain Methyltransf_31 PF13847.6 KXZ41697.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ41697.1 - 0.0015 18.1 0.1 0.0098 15.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KXZ41697.1 - 0.0038 16.7 0.4 0.0096 15.3 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXZ41697.1 - 0.0045 17.7 0.2 0.015 16.0 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ41697.1 - 0.077 13.7 0.1 0.77 10.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ41697.1 - 0.18 12.6 0.1 2.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain AsnC_trans_reg2 PF17805.1 KXZ41699.1 - 0.025 14.7 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 AsnC-like ligand binding domain JAKMIP_CC3 PF16034.5 KXZ41699.1 - 0.16 11.9 1.9 0.25 11.3 1.9 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain ZapB PF06005.12 KXZ41699.1 - 0.79 10.2 4.5 2.5 8.6 4.5 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Guanylate_cyc PF00211.20 KXZ41700.1 - 1.4e-54 184.5 0.0 2.4e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Lipase_GDSL_2 PF13472.6 KXZ41702.1 - 4.5e-16 59.7 0.1 5.4e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXZ41702.1 - 0.0026 17.8 0.0 0.0051 16.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DrsE PF02635.15 KXZ41702.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 DsrE/DsrF-like family Lipase_GDSL_2 PF13472.6 KXZ41703.1 - 2.8e-14 53.9 0.0 3.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXZ41703.1 - 0.0021 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DrsE PF02635.15 KXZ41703.1 - 0.017 15.5 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 DsrE/DsrF-like family RtcB PF01139.17 KXZ41704.1 - 4.9e-37 128.1 0.0 6.2e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Chlam_PMP PF02415.17 KXZ41705.1 - 0.013 16.0 11.1 0.16 12.5 0.5 3.7 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chlam_PMP PF02415.17 KXZ41706.1 - 0.0095 16.4 1.5 0.0095 16.4 1.5 2.3 2 0 0 2 2 2 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glyco_hydro_9 PF00759.19 KXZ41709.1 - 1.8e-63 215.4 17.9 2.4e-63 215.0 17.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF4262 PF14081.6 KXZ41710.1 - 0.018 15.2 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) Ank_2 PF12796.7 KXZ41711.1 - 1.3e-07 32.0 0.1 0.024 15.2 0.0 4.3 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41711.1 - 8.2e-06 26.3 1.6 0.069 13.8 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41711.1 - 0.079 13.6 2.6 61 4.7 0.0 5.0 7 0 0 7 7 7 0 Ankyrin repeat Peptidase_C48 PF02902.19 KXZ41713.1 - 1.2e-14 54.7 0.0 6.7e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PhyH PF05721.13 KXZ41713.1 - 0.0027 18.0 0.1 0.0066 16.7 0.1 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CPT PF07931.12 KXZ41713.1 - 0.22 11.3 0.8 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Thioesterase PF00975.20 KXZ41714.1 - 4.6e-13 49.8 0.0 7.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Guanylate_cyc PF00211.20 KXZ41715.1 - 5.7e-34 117.3 0.0 1.1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ41716.1 - 2.2e-20 73.0 0.0 3.8e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3416 PF11896.8 KXZ41716.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) ABC_tran PF00005.27 KXZ41717.1 - 9.9e-48 162.1 0.0 1.4e-23 83.9 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXZ41717.1 - 2.9e-18 66.7 0.1 0.0001 22.3 0.0 4.8 4 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ41717.1 - 5e-16 58.8 0.0 2.2e-06 27.3 0.0 3.6 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ41717.1 - 1.5e-06 27.9 0.0 0.041 13.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXZ41717.1 - 1.6e-06 28.2 0.1 0.1 12.5 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 KXZ41717.1 - 2.1e-06 28.1 0.1 0.12 12.7 0.0 4.1 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KXZ41717.1 - 3.8e-06 27.0 0.0 0.061 13.4 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Chromo PF00385.24 KXZ41717.1 - 6.7e-06 25.9 0.3 1.6e-05 24.7 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 4HB PF17947.1 KXZ41717.1 - 7.7e-06 25.9 0.0 3.1e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 Four helical bundle domain AAA_23 PF13476.6 KXZ41717.1 - 1e-05 26.1 11.9 0.0041 17.6 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXZ41717.1 - 3e-05 24.5 1.1 0.14 12.6 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain CLASP_N PF12348.8 KXZ41717.1 - 3.1e-05 23.6 0.1 7.9e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 CLASP N terminal AAA PF00004.29 KXZ41717.1 - 3.2e-05 24.3 0.0 0.094 13.1 0.0 3.9 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXZ41717.1 - 0.00016 21.9 0.0 0.34 11.1 0.1 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KXZ41717.1 - 0.00027 21.1 1.1 0.17 12.1 0.0 3.6 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KXZ41717.1 - 0.00031 21.3 0.0 0.45 11.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KXZ41717.1 - 0.00045 20.4 0.0 1.8 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KXZ41717.1 - 0.00048 19.2 0.0 0.7 8.8 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KXZ41717.1 - 0.00048 20.5 0.0 0.88 10.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase HEAT PF02985.22 KXZ41717.1 - 0.0015 18.6 1.5 2.8 8.4 0.0 5.3 5 0 0 5 5 4 1 HEAT repeat DUF815 PF05673.13 KXZ41717.1 - 0.0025 17.0 0.1 0.41 9.8 0.0 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Vac14_Fab1_bd PF12755.7 KXZ41717.1 - 0.0037 17.8 0.0 1.3 9.7 0.0 2.8 1 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region AAA_24 PF13479.6 KXZ41717.1 - 0.0039 17.0 0.1 1.9 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXZ41717.1 - 0.0041 16.6 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KXZ41717.1 - 0.012 15.6 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 KXZ41717.1 - 0.015 15.5 0.0 5.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NUC173 PF08161.12 KXZ41717.1 - 0.019 14.6 0.2 5.1 6.7 0.0 2.6 1 1 1 2 2 2 0 NUC173 domain HEAT_EZ PF13513.6 KXZ41717.1 - 0.022 15.3 9.3 1.4 9.5 0.0 4.5 4 0 0 4 4 3 0 HEAT-like repeat CLP1_P PF16575.5 KXZ41717.1 - 0.022 14.5 0.2 1.1 9.0 0.0 2.7 2 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 KXZ41717.1 - 0.023 14.4 6.1 2.7 7.7 0.0 3.9 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 KXZ41717.1 - 0.024 14.6 0.0 7.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain UME PF08064.13 KXZ41717.1 - 0.034 14.1 0.1 0.29 11.1 0.0 2.5 1 1 1 2 2 2 0 UME (NUC010) domain ATPase_2 PF01637.18 KXZ41717.1 - 0.035 14.0 0.6 7 6.5 0.0 3.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 KXZ41717.1 - 0.038 13.7 6.1 1.4 8.5 0.0 4.1 4 1 1 5 5 5 0 AAA ATPase domain AAA_27 PF13514.6 KXZ41717.1 - 0.039 13.5 0.0 7.5 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXZ41717.1 - 0.047 13.4 0.1 6 6.6 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KXZ41717.1 - 0.08 12.8 0.2 6.6 6.6 0.0 2.8 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 KXZ41717.1 - 0.21 11.7 8.5 6.1 6.9 0.1 4.2 5 0 0 5 5 4 0 Helicase HerA, central domain MutS_III PF05192.18 KXZ41718.1 - 2.5e-21 76.8 0.0 3.8e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXZ41718.1 - 5.3e-15 55.6 0.0 8e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain I CAP_N PF01213.19 KXZ41718.1 - 4.2 6.8 4.5 2.9 7.3 0.8 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Snf7 PF03357.21 KXZ41721.1 - 5.8e-29 100.9 1.5 5.8e-29 100.9 1.5 1.8 1 1 1 2 2 2 1 Snf7 DUF2884 PF11101.8 KXZ41721.1 - 2.7 7.4 6.0 10 5.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) CoA_binding_2 PF13380.6 KXZ41722.1 - 1.9e-29 102.5 0.3 2.2e-29 102.3 0.3 1.1 1 0 0 1 1 1 1 CoA binding domain AIRS PF00586.24 KXZ41722.1 - 0.17 12.5 0.4 0.46 11.2 0.1 1.8 2 1 0 2 2 2 0 AIR synthase related protein, N-terminal domain EF-hand_1 PF00036.32 KXZ41724.1 - 3.5e-37 123.2 18.2 2.1e-09 36.3 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ41724.1 - 9.5e-32 109.3 9.9 3.8e-16 59.3 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ41724.1 - 5.2e-30 100.8 11.3 1.3e-09 37.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXZ41724.1 - 1.2e-26 92.3 17.2 2.1e-12 46.7 0.9 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXZ41724.1 - 2e-21 74.5 19.9 4.8e-06 25.8 0.2 4.5 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXZ41724.1 - 2.4e-13 50.2 0.3 1.9e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXZ41724.1 - 1.7e-07 31.1 6.4 0.062 13.2 0.4 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KXZ41724.1 - 3.1e-06 27.3 0.3 0.0029 17.8 0.1 2.3 2 0 0 2 2 2 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KXZ41724.1 - 0.0003 21.1 0.1 0.16 12.3 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF853 PF05872.12 KXZ41724.1 - 0.00066 18.4 0.2 0.65 8.5 0.0 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) SurA_N_3 PF13624.6 KXZ41724.1 - 0.0011 18.8 1.0 0.14 11.9 0.1 2.1 1 1 1 2 2 2 2 SurA N-terminal domain TerB PF05099.13 KXZ41724.1 - 0.0048 16.9 4.0 0.15 12.0 0.0 2.9 1 1 2 3 3 3 1 Tellurite resistance protein TerB SurA_N_2 PF13623.6 KXZ41724.1 - 0.0083 16.0 0.6 3.5 7.5 0.0 2.5 2 1 0 2 2 2 2 SurA N-terminal domain PMBR PF09373.10 KXZ41724.1 - 0.0083 16.2 0.3 20 5.6 0.0 4.4 5 0 0 5 5 4 0 Pseudomurein-binding repeat EF-hand_14 PF17959.1 KXZ41724.1 - 0.011 16.1 0.9 4.1 7.8 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 KXZ41724.1 - 0.012 15.5 0.8 6.8 6.6 0.0 3.4 1 1 3 4 4 4 0 Caleosin related protein EcoR124_C PF12008.8 KXZ41724.1 - 0.017 14.8 4.1 0.017 14.8 3.1 1.5 1 1 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal EF-hand_11 PF08976.11 KXZ41724.1 - 0.021 15.7 0.1 5.4 8.0 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain Sigma54_CBD PF04963.13 KXZ41724.1 - 0.04 13.8 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain DUF5380 PF17351.2 KXZ41724.1 - 0.085 12.7 0.3 2.1 8.3 0.0 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5380) Gp-FAR-1 PF05823.12 KXZ41724.1 - 0.1 13.0 3.5 0.55 10.6 0.1 2.8 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) UPF0154 PF03672.13 KXZ41724.1 - 0.1 12.6 0.0 6.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Acetyltransf_11 PF13720.6 KXZ41724.1 - 0.11 13.0 0.0 2.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PB1 PF00564.24 KXZ41724.1 - 0.17 11.9 0.9 6 6.9 0.1 2.8 2 1 1 3 3 3 0 PB1 domain DUF2757 PF10955.8 KXZ41724.1 - 0.25 11.6 0.9 7 7.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) Hydrolase_6 PF13344.6 KXZ41725.1 - 1.5e-15 57.1 0.0 2.2e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ41725.1 - 3.5e-13 49.4 0.2 1.1e-12 47.9 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 KXZ41725.1 - 2.9e-08 34.0 0.0 7.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ41725.1 - 2.2e-07 31.4 0.1 0.025 14.9 0.2 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ41725.1 - 0.074 13.4 0.1 0.27 11.6 0.0 1.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 KXZ41726.1 - 7.3e-30 103.4 0.5 2.4e-13 50.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ41726.1 - 2.2e-28 97.4 0.2 8.5e-06 26.0 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KXZ41726.1 - 9e-25 84.1 0.0 7.1e-05 22.9 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXZ41726.1 - 1e-23 83.0 0.8 1.3e-07 31.7 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ41726.1 - 3.9e-21 75.1 0.0 1.7e-08 34.8 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) HC2 PF07382.11 KXZ41726.1 - 3.1e-05 24.1 6.0 8.9e-05 22.6 6.1 1.6 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Ldh_1_C PF02866.18 KXZ41726.1 - 0.043 13.7 0.3 0.5 10.3 0.1 2.2 1 1 1 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain CCSAP PF15748.5 KXZ41726.1 - 1.5 9.0 10.6 2.7 8.1 10.6 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Cyt-b5 PF00173.28 KXZ41727.1 - 2.5e-10 40.3 0.1 3.8e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PAS_3 PF08447.12 KXZ41727.1 - 0.05 13.9 0.2 11 6.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold DUF2264 PF10022.9 KXZ41728.1 - 5.3e-75 252.7 0.1 6e-75 252.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) NYD-SP28_assoc PF14775.6 KXZ41728.1 - 0.11 12.6 0.3 0.31 11.2 0.3 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4708 PF15813.5 KXZ41728.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) Epimerase PF01370.21 KXZ41729.1 - 3.2e-05 23.5 0.0 0.00034 20.2 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXZ41729.1 - 0.029 13.5 0.0 0.078 12.1 0.0 1.6 1 1 1 2 2 2 0 Male sterility protein Proteasome PF00227.26 KXZ41732.1 - 2.4e-49 167.4 0.2 3e-49 167.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Aldo_ket_red PF00248.21 KXZ41733.1 - 5.4e-71 239.2 0.0 6.2e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SATase_N PF06426.14 KXZ41733.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal RVT_2 PF07727.14 KXZ41734.1 - 3.2e-33 115.4 0.0 1.5e-18 67.3 0.0 3.1 1 1 2 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KXZ41734.1 - 5.7e-09 35.8 0.0 9.6e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PAM2 PF07145.15 KXZ41734.1 - 0.38 10.5 4.2 1.3e+02 2.7 0.0 4.5 5 0 0 5 5 5 0 Ataxin-2 C-terminal region DUF1707 PF08044.11 KXZ41736.1 - 9.7 6.3 23.5 2.6 8.2 1.7 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) PHTB1_N PF14727.6 KXZ41737.1 - 1.4e-133 446.3 0.0 1.7e-133 446.0 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 KXZ41737.1 - 1.1e-103 347.2 0.0 1.5e-103 346.8 0.0 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus CAP_N PF01213.19 KXZ41737.1 - 1.8 7.9 3.4 3.4 7.1 3.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal OCRE PF17780.1 KXZ41737.1 - 3.6 7.7 6.6 27 4.9 0.7 2.8 1 1 2 3 3 3 0 OCRE domain zf-rbx1 PF12678.7 KXZ41740.1 - 1.9e-05 24.9 5.2 1.9e-05 24.9 5.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXZ41740.1 - 0.00022 21.5 6.1 0.00022 21.5 6.1 3.1 3 0 0 3 3 3 1 Ring finger domain zf-ANAPC11 PF12861.7 KXZ41740.1 - 0.00028 20.9 1.3 0.00028 20.9 1.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KXZ41740.1 - 0.0093 15.8 5.4 0.0093 15.8 5.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ41740.1 - 0.041 13.9 2.9 0.11 12.6 2.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KXZ41740.1 - 0.2 11.9 5.3 0.068 13.4 2.3 1.7 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KXZ41740.1 - 3.9 7.3 10.1 0.72 9.7 1.4 2.9 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_5 PF14634.6 KXZ41740.1 - 4.1 7.4 11.8 0.29 11.1 5.4 2.3 2 0 0 2 2 2 0 zinc-RING finger domain UQ_con PF00179.26 KXZ41741.1 - 2.3e-26 92.1 0.0 4.7e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KXZ41741.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain SDA1 PF05285.12 KXZ41741.1 - 0.12 11.8 8.0 0.21 11.0 8.0 1.3 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 KXZ41741.1 - 3.8 7.2 8.0 8 6.1 8.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 KXZ41741.1 - 4.6 7.3 6.5 9.1 6.3 6.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein tRNA_U5-meth_tr PF05958.11 KXZ41742.1 - 0.073 12.1 0.0 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 KXZ41742.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 KXZ41742.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein WRNPLPNID PF15017.6 KXZ41742.1 - 0.3 12.0 1.2 1.2 10.1 0.5 2.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Glyco_hydro_130 PF04041.13 KXZ41743.1 - 0.099 11.5 0.0 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase RWP-RK PF02042.15 KXZ41745.1 - 1.2e-15 57.2 0.4 1.6e-15 56.8 0.4 1.2 1 0 0 1 1 1 1 RWP-RK domain Ribosomal_60s PF00428.19 KXZ41745.1 - 0.015 15.9 1.9 0.023 15.3 1.9 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein HTH_AraC PF00165.23 KXZ41745.1 - 0.033 14.3 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_6 PF01418.17 KXZ41745.1 - 0.083 12.9 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family MttA_Hcf106 PF02416.16 KXZ41745.1 - 0.18 11.2 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family Astro_capsid_p PF12226.8 KXZ41745.1 - 0.33 10.0 1.9 0.4 9.8 1.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RWP-RK PF02042.15 KXZ41746.1 - 1.1e-14 54.2 0.4 1.8e-14 53.4 0.4 1.4 1 0 0 1 1 1 1 RWP-RK domain PBP1_TM PF14812.6 KXZ41746.1 - 4.6 7.7 7.6 8.7 6.8 7.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3598 PF12204.8 KXZ41747.1 - 0.0084 15.6 0.0 0.052 13.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3598) Ank_2 PF12796.7 KXZ41748.1 - 6.7e-14 52.2 0.0 0.00027 21.5 0.0 4.4 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41748.1 - 1.3e-09 38.4 1.4 0.31 11.7 0.0 6.7 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41748.1 - 9.7e-06 25.6 5.1 4.2 8.3 0.0 7.9 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ41748.1 - 0.01 16.2 7.7 13 6.2 0.1 6.2 3 3 3 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41748.1 - 0.078 13.5 0.2 2.9 8.5 0.0 3.6 5 0 0 5 5 5 0 Ankyrin repeat Pkinase PF00069.25 KXZ41749.1 - 3.6e-39 134.7 0.0 9.7e-26 90.7 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41749.1 - 8.5e-13 48.2 0.0 2.9e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1604 PF07713.13 KXZ41750.1 - 6.3e-36 122.1 1.2 1e-35 121.4 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) Sororin PF09666.10 KXZ41750.1 - 0.016 15.5 0.3 0.021 15.1 0.3 1.1 1 0 0 1 1 1 0 Sororin protein DUF2597 PF10772.9 KXZ41751.1 - 0.077 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Spore_YhaL PF14147.6 KXZ41751.1 - 0.19 11.5 1.9 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein YhaL Histone PF00125.24 KXZ41752.1 - 4.5e-39 133.8 0.3 5e-39 133.7 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ41752.1 - 8.6e-05 22.9 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ41752.1 - 0.0003 20.9 0.1 0.00039 20.5 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ41752.1 - 0.0034 17.6 0.1 0.0047 17.2 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ41752.1 - 0.0065 16.5 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ank_2 PF12796.7 KXZ41753.1 - 0.0011 19.5 0.0 4.3 8.0 0.0 3.9 4 2 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41753.1 - 0.0013 19.0 2.5 23 6.0 0.0 5.7 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 KXZ41753.1 - 0.0027 18.2 4.7 3.5 8.3 0.0 5.3 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Dynamin_N PF00350.23 KXZ41754.1 - 0.00084 19.4 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Ribosomal_S30AE PF02482.19 KXZ41754.1 - 0.21 12.4 1.9 0.35 11.7 0.2 2.3 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein SDA1 PF05285.12 KXZ41754.1 - 4.3 6.7 20.0 8 5.8 20.0 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXZ41754.1 - 5.4 5.1 17.6 9.9 4.2 17.6 1.3 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.8 KXZ41756.1 - 0.024 15.6 3.7 0.025 15.6 1.9 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CBM_4_9 PF02018.17 KXZ41758.1 - 2.6e-08 34.2 3.3 0.0032 17.7 0.1 2.6 3 0 0 3 3 3 2 Carbohydrate binding domain Phage_H_T_join PF05521.11 KXZ41758.1 - 0.93 10.1 4.7 5.3 7.6 0.1 3.2 2 2 2 4 4 4 0 Phage head-tail joining protein Ank_2 PF12796.7 KXZ41759.1 - 1.6e-43 147.2 11.4 9.5e-17 61.4 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41759.1 - 2.9e-39 133.0 9.2 1.1e-11 45.0 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41759.1 - 1.1e-36 123.7 13.8 3.4e-07 30.4 0.1 5.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KXZ41759.1 - 2.5e-32 107.2 2.0 1.2e-05 25.3 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KXZ41759.1 - 2.1e-26 91.6 15.3 1.3e-07 31.7 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) HTH_16 PF12645.7 KXZ41759.1 - 2.7e-05 24.1 5.4 0.64 10.1 0.1 4.3 4 0 0 4 4 4 1 Helix-turn-helix domain Calponin PF00402.18 KXZ41759.1 - 0.025 14.2 3.8 40 4.0 0.1 4.2 4 0 0 4 4 4 0 Calponin family repeat DUF3764 PF12594.8 KXZ41759.1 - 0.099 12.7 0.0 12 6.0 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3764) HEAT_PBS PF03130.16 KXZ41759.1 - 0.46 11.3 6.4 61 4.7 0.2 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Ank_2 PF12796.7 KXZ41760.1 - 4.6e-53 177.8 13.4 5.4e-15 55.8 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ41760.1 - 1.3e-49 164.5 17.1 3.1e-07 30.6 0.1 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 KXZ41760.1 - 2e-44 149.4 4.9 2.3e-11 44.0 0.2 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41760.1 - 8.2e-42 136.4 5.2 2.5e-05 24.3 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 KXZ41760.1 - 4.2e-28 97.0 17.2 8.8e-07 29.1 0.1 6.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) FemAB_like PF04339.12 KXZ41760.1 - 0.00035 19.8 5.1 3.3 6.7 0.1 4.1 1 1 2 4 4 4 2 Peptidogalycan biosysnthesis/recognition HTH_16 PF12645.7 KXZ41760.1 - 0.011 15.7 10.8 37 4.5 0.0 5.7 7 0 0 7 7 7 0 Helix-turn-helix domain Calponin PF00402.18 KXZ41760.1 - 0.015 15.0 5.8 46 3.8 0.0 5.7 6 0 0 6 6 6 0 Calponin family repeat PhoPQ_related PF10142.9 KXZ41760.1 - 0.063 11.9 0.4 6.2 5.4 0.0 2.5 2 1 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein DUF2202 PF09968.9 KXZ41760.1 - 0.21 11.4 0.0 62 3.4 0.0 3.8 4 1 1 5 5 5 0 Uncharacterized protein domain (DUF2202) DUF1593 PF07632.11 KXZ41760.1 - 0.94 8.9 6.0 21 4.4 0.2 3.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1593) Ank_5 PF13857.6 KXZ41761.1 - 3.7e-20 71.7 0.6 9.3e-11 41.8 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41761.1 - 3.7e-17 61.9 3.5 3.9e-06 27.1 0.0 4.8 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXZ41761.1 - 8.3e-17 61.3 0.0 1.3e-07 32.0 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ41761.1 - 6.1e-16 58.8 0.0 1.6e-08 35.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41761.1 - 1.8e-12 46.2 0.0 0.00026 21.2 0.0 4.2 5 0 0 5 5 3 2 Ankyrin repeat Roc PF08477.13 KXZ41761.1 - 1e-09 38.7 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ41761.1 - 7.4e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ41761.1 - 2e-07 30.6 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXZ41761.1 - 0.0019 17.6 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KXZ41761.1 - 0.0027 17.9 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 KXZ41761.1 - 0.0032 16.9 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 KXZ41761.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 KXZ41761.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KXZ41761.1 - 0.018 15.5 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 KXZ41761.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 KXZ41761.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KXZ41761.1 - 0.041 14.3 0.1 0.087 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXZ41761.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXZ41761.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ41761.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXZ41761.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXZ41761.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ank_2 PF12796.7 KXZ41762.1 - 5.4e-27 94.2 0.0 1.1e-11 45.2 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41762.1 - 3.4e-25 85.4 0.4 0.0001 22.4 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KXZ41762.1 - 1.8e-24 85.0 7.2 2.5e-05 24.5 0.0 5.1 4 1 1 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KXZ41762.1 - 2.7e-24 84.9 1.8 8.2e-10 38.7 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ41762.1 - 2.5e-18 66.2 0.5 9.1e-10 38.9 0.0 3.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) DUF2384 PF09722.10 KXZ41762.1 - 0.013 15.5 2.6 9 6.4 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) Rhomboid PF01694.22 KXZ41763.1 - 4.9e-17 62.3 9.3 4.9e-17 62.3 9.3 1.5 2 0 0 2 2 2 1 Rhomboid family DUF5429 PF17494.2 KXZ41763.1 - 0.019 15.0 0.1 0.07 13.2 0.1 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5429) Mito_carr PF00153.27 KXZ41764.1 - 2.1e-08 34.0 0.8 8.5e-08 32.0 0.1 2.2 2 1 0 2 2 2 1 Mitochondrial carrier protein ABC_tran PF00005.27 KXZ41765.1 - 3.3e-06 27.6 0.0 6.5e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KXZ41765.1 - 9.8e-05 21.9 0.1 0.00013 21.5 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain GSH-S_ATP PF02955.16 KXZ41765.1 - 0.051 13.0 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain RLI PF04068.15 KXZ41766.1 - 8.2e-14 51.1 6.1 2.1e-13 49.9 6.1 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 KXZ41766.1 - 1.2e-08 34.4 3.3 1.2e-08 34.4 3.3 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain ABC_tran PF00005.27 KXZ41766.1 - 2.1e-08 34.8 0.0 3.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Fer4_6 PF12837.7 KXZ41766.1 - 5.1e-06 26.3 12.4 8e-06 25.7 2.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 KXZ41766.1 - 1.9e-05 25.1 5.0 0.00035 21.1 0.2 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KXZ41766.1 - 6.3e-05 22.8 0.7 6.3e-05 22.8 0.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SMC_N PF02463.19 KXZ41766.1 - 7.6e-05 22.3 0.1 0.00016 21.2 0.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Fer4_10 PF13237.6 KXZ41766.1 - 0.00078 19.5 1.1 0.00078 19.5 1.1 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KXZ41766.1 - 0.00097 19.2 13.4 0.0023 18.0 13.4 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXZ41766.1 - 0.0018 18.4 11.9 0.0051 17.0 12.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXZ41766.1 - 0.063 14.2 2.2 0.063 14.2 2.2 2.7 1 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 KXZ41766.1 - 0.063 13.8 1.5 0.063 13.8 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KXZ41766.1 - 0.34 11.5 14.9 0.08 13.5 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 KXZ41766.1 - 0.49 10.9 10.2 0.14 12.7 1.2 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Alba PF01918.21 KXZ41769.1 - 4.6e-18 64.8 1.6 7.2e-18 64.2 1.6 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 KXZ41769.1 - 3.7e-07 30.2 0.1 4.9e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P MMS1_N PF10433.9 KXZ41770.1 - 0.00035 19.3 0.0 0.0019 16.9 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Plug_translocon PF10559.9 KXZ41770.1 - 0.024 14.5 0.2 0.068 13.0 0.2 1.8 1 0 0 1 1 1 0 Plug domain of Sec61p Ank_2 PF12796.7 KXZ41771.1 - 3.6e-06 27.5 0.3 0.14 12.8 0.2 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41771.1 - 0.0017 18.7 0.6 18 6.3 0.0 5.4 6 1 1 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 KXZ41771.1 - 0.01 16.4 4.7 16 6.2 0.0 4.4 4 2 0 4 4 4 0 Ankyrin repeats (many copies) DUF4224 PF13986.6 KXZ41771.1 - 0.16 11.9 0.7 31 4.6 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4224) Pkinase_Tyr PF07714.17 KXZ41772.1 - 7.1e-43 146.8 0.0 8.7e-40 136.6 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ41772.1 - 2.7e-36 125.3 0.0 7.7e-33 114.0 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 KXZ41772.1 - 0.3 10.3 0.0 0.49 9.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF4504 PF14953.6 KXZ41773.1 - 5.3e-05 22.8 0.0 6.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) Tim17 PF02466.19 KXZ41774.1 - 5.4e-05 23.5 0.1 8.2e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_M16_C PF05193.21 KXZ41775.1 - 0.0083 16.2 0.4 0.014 15.4 0.4 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain MSA-2c PF12238.8 KXZ41776.1 - 0.1 12.6 0.4 0.12 12.3 0.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c RRS1 PF04939.12 KXZ41777.1 - 4.3e-49 166.5 0.0 7.2e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Pkinase PF00069.25 KXZ41779.1 - 6.2e-07 29.0 0.0 8.7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41779.1 - 0.0046 16.3 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ41779.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ41779.1 - 0.013 15.5 1.4 0.014 15.3 0.5 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ41779.1 - 0.04 12.7 0.1 0.067 11.9 0.0 1.3 2 0 0 2 2 2 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KXZ41779.1 - 0.14 11.1 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Roc PF08477.13 KXZ41780.1 - 3.6e-06 27.2 0.0 4.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KXZ41780.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 KXZ41780.1 - 0.022 14.4 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Ras family Arf PF00025.21 KXZ41780.1 - 0.082 12.4 0.0 0.11 11.9 0.0 1.2 1 1 0 1 1 1 0 ADP-ribosylation factor family IstB_IS21 PF01695.17 KXZ41780.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KXZ41780.1 - 0.18 11.8 0.1 0.25 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXZ41780.1 - 0.21 10.9 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABATE PF07336.11 KXZ41782.1 - 0.0076 16.9 0.0 0.0081 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative stress-induced transcription regulator Homeobox_KN PF05920.11 KXZ41783.1 - 3.1e-06 27.0 0.6 5.3e-06 26.2 0.6 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXZ41783.1 - 0.029 14.2 0.3 0.053 13.4 0.3 1.4 1 0 0 1 1 1 0 Homeodomain BTRD1 PF17660.1 KXZ41783.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 TTL PF03133.15 KXZ41785.1 - 3.6e-72 243.0 0.0 5.7e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ41785.1 - 1.5e-07 31.0 0.1 0.00016 21.0 0.0 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ41785.1 - 1.7e-05 24.2 0.0 0.0045 16.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF2967 PF11179.8 KXZ41785.1 - 0.0071 14.5 4.1 0.013 13.6 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) ATP-grasp_3 PF02655.14 KXZ41785.1 - 0.019 15.0 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Cgr1 PF03879.14 KXZ41785.1 - 3.6 8.0 15.0 0.2 12.0 7.5 2.3 2 0 0 2 2 2 0 Cgr1 family CHCH PF06747.13 KXZ41786.1 - 9.5e-08 32.0 4.5 1.3e-07 31.6 4.5 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KXZ41786.1 - 0.00011 22.1 0.4 0.00014 21.8 0.4 1.1 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, KleE PF17394.2 KXZ41786.1 - 0.032 14.5 1.3 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein SBP PF03110.14 KXZ41787.1 - 7e-26 90.3 11.0 1.3e-25 89.5 11.0 1.4 1 0 0 1 1 1 1 SBP domain BTB PF00651.31 KXZ41787.1 - 3.5e-12 46.5 0.0 6.7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DNA_pol_alpha_N PF12254.8 KXZ41788.1 - 2e-21 75.8 7.3 2.4e-21 75.6 7.3 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal CENP-F_leu_zip PF10473.9 KXZ41791.1 - 8.2e-05 22.6 14.3 0.0039 17.2 0.2 3.7 2 2 0 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KXZ41791.1 - 0.0016 17.4 19.2 0.0035 16.3 2.5 2.5 2 1 0 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 KXZ41791.1 - 0.011 15.1 12.5 0.12 11.7 0.7 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KXZ41791.1 - 0.033 14.8 3.1 6.2 7.5 0.2 3.6 2 1 2 4 4 4 0 Initiation control protein YabA UPF0242 PF06785.11 KXZ41791.1 - 0.079 13.1 4.4 4.5 7.3 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KXZ41791.1 - 0.14 11.5 51.5 0.11 11.8 2.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF2353 PF09789.9 KXZ41791.1 - 0.15 11.4 6.3 13 5.0 0.0 3.1 2 1 0 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.11 KXZ41791.1 - 0.16 12.2 45.4 0.084 13.1 13.7 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KXZ41791.1 - 0.26 11.5 17.5 5.4 7.3 5.1 4.1 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 KXZ41791.1 - 0.27 10.9 17.1 1.6 8.4 7.1 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 KXZ41791.1 - 0.38 11.2 14.2 2 8.8 4.6 3.2 1 1 1 2 2 2 0 Fez1 Baculo_PEP_C PF04513.12 KXZ41791.1 - 0.77 9.8 5.3 3.8 7.5 0.9 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus JIP_LZII PF16471.5 KXZ41791.1 - 1.2 9.3 5.9 11 6.3 0.0 4.0 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II Cnn_1N PF07989.11 KXZ41791.1 - 1.7 8.9 5.7 11 6.3 0.3 3.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 KXZ41791.1 - 1.9 7.5 11.6 1.5 7.8 3.5 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FH2 PF02181.23 KXZ41791.1 - 2.4 7.2 4.1 2 7.4 0.4 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain Golgin_A5 PF09787.9 KXZ41791.1 - 3.9 6.8 12.2 2.2 7.7 5.6 2.8 2 1 0 2 2 2 0 Golgin subfamily A member 5 Myosin_tail_1 PF01576.19 KXZ41791.1 - 4.2 5.0 28.6 1.1 7.0 0.5 3.1 2 1 0 3 3 3 0 Myosin tail Filament PF00038.21 KXZ41791.1 - 5.9 6.4 23.9 2.1 7.8 3.8 4.0 2 2 2 4 4 4 0 Intermediate filament protein ADIP PF11559.8 KXZ41791.1 - 9.5 6.3 24.2 2.1 8.4 4.6 3.7 3 1 2 5 5 4 0 Afadin- and alpha -actinin-Binding YscO-like PF16789.5 KXZ41791.1 - 9.6 6.2 11.9 0.19 11.8 3.3 2.4 2 1 1 3 3 3 0 YscO-like protein Helitron_like_N PF14214.6 KXZ41792.1 - 1.8e-12 47.9 0.0 3.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF2786 PF10979.8 KXZ41792.1 - 0.055 13.4 1.3 0.23 11.4 1.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Tegument_dsDNA PF12818.7 KXZ41792.1 - 0.056 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 dsDNA viral tegument protein ThiC-associated PF13667.6 KXZ41795.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 ThiC-associated domain DSS1_SEM1 PF05160.13 KXZ41796.1 - 5.6e-16 58.4 13.0 8e-16 57.8 13.0 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family tRNA_anti-like PF12869.7 KXZ41796.1 - 0.33 10.6 1.9 0.42 10.2 1.9 1.2 1 0 0 1 1 1 0 tRNA_anti-like SQS_PSY PF00494.19 KXZ41797.1 - 2.9e-71 240.1 0.4 3.4e-71 239.9 0.4 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Myb_DNA-binding PF00249.31 KXZ41798.1 - 8.7e-20 70.7 4.6 8.7e-14 51.5 1.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ41798.1 - 1.4e-11 44.5 0.1 1e-05 25.7 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HD PF01966.22 KXZ41799.1 - 4.1e-09 36.7 0.6 1.7e-08 34.7 0.6 2.1 1 1 0 1 1 1 1 HD domain PLAC8 PF04749.17 KXZ41799.1 - 5.5e-07 30.5 0.7 1.3e-06 29.3 0.7 1.7 1 0 0 1 1 1 1 PLAC8 family Yae1_N PF09811.9 KXZ41800.1 - 5.5e-07 29.2 2.5 8.2e-07 28.6 2.5 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RNA_pol PF00940.19 KXZ41801.1 - 5.9e-68 229.6 0.0 1.1e-67 228.8 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KXZ41801.1 - 1.9e-32 113.0 0.0 9.7e-27 94.2 0.0 2.2 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal PGA2 PF07543.12 KXZ41802.1 - 0.15 12.0 2.9 0.22 11.5 1.7 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 zf-CCCH PF00642.24 KXZ41805.1 - 7e-18 64.1 24.0 2.6e-05 24.0 1.5 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXZ41805.1 - 7.5e-18 65.2 20.8 9e-06 26.3 0.6 4.3 1 1 3 4 4 4 4 Torus domain zf_CCCH_4 PF18345.1 KXZ41805.1 - 3.4e-16 58.7 38.8 3.6e-05 23.7 2.2 4.4 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 KXZ41805.1 - 7e-10 38.5 31.7 0.00023 20.9 2.0 4.3 4 0 0 4 4 4 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXZ41805.1 - 0.00047 20.3 19.4 0.44 10.8 0.2 4.2 2 1 2 4 4 4 4 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXZ41805.1 - 0.047 14.2 25.5 0.82 10.2 0.3 4.4 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger SbcCD_C PF13558.6 KXZ41805.1 - 0.89 9.8 3.7 2.8 8.3 0.3 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KXZ41806.1 - 2.3e-37 128.5 0.0 6.3e-16 59.1 0.0 3.5 3 0 0 3 3 3 3 ABC transporter AAA_21 PF13304.6 KXZ41806.1 - 3.8e-20 72.9 3.7 3.1e-06 27.2 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ41806.1 - 1.5e-10 40.9 0.0 0.12 11.8 0.0 4.1 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ41806.1 - 4.3e-05 23.2 0.2 0.13 12.1 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXZ41806.1 - 0.00014 22.4 0.0 0.51 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXZ41806.1 - 0.00024 21.2 0.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXZ41806.1 - 0.0027 17.6 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KXZ41806.1 - 0.023 14.4 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KXZ41806.1 - 0.032 14.2 0.1 8.2 6.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KXZ41806.1 - 0.045 13.3 1.8 1 8.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF2052 PF09747.9 KXZ41806.1 - 0.053 13.6 0.5 0.088 12.9 0.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF815 PF05673.13 KXZ41806.1 - 0.24 10.5 3.2 1.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) DUF2813 PF11398.8 KXZ41806.1 - 0.26 10.5 0.2 4.8 6.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_16 PF13191.6 KXZ41806.1 - 1.9 8.8 20.5 2.2 8.7 0.5 3.6 2 2 0 2 2 2 0 AAA ATPase domain Ribosomal_L12 PF00542.19 KXZ41807.1 - 3.8e-26 91.2 5.5 6.2e-26 90.5 5.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KXZ41807.1 - 0.0054 16.4 26.4 0.34 10.6 18.1 3.8 3 1 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain Bap31_Bap29_C PF18035.1 KXZ41807.1 - 0.011 15.7 0.6 0.011 15.7 0.6 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain MctB PF11382.8 KXZ41807.1 - 0.031 14.0 0.8 0.034 13.9 0.5 1.4 1 1 0 1 1 1 0 Copper transport outer membrane protein, MctB Ribosomal_60s PF00428.19 KXZ41807.1 - 1.4 9.6 22.3 0.13 12.9 15.8 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein PP2C PF00481.21 KXZ41809.1 - 4.9e-52 177.1 0.0 6.5e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXZ41809.1 - 5.9e-06 26.1 1.4 1.4e-05 24.8 1.4 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DPBB_1 PF03330.18 KXZ41810.1 - 8.5e-10 38.8 0.2 1.7e-09 37.8 0.2 1.5 1 0 0 1 1 1 1 Lytic transglycolase DNA_mis_repair PF01119.19 KXZ41811.1 - 1.5e-16 60.2 0.0 2.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXZ41811.1 - 5e-12 45.8 0.0 9.4e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXZ41811.1 - 6.8e-08 33.0 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAP_N PF01213.19 KXZ41813.1 - 2.9e-61 207.7 0.0 4.7e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KXZ41813.1 - 2e-48 164.0 0.1 2.6e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KXZ41813.1 - 0.01 15.6 1.0 0.017 14.8 1.0 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C SNARE PF05739.19 KXZ41814.1 - 3.4e-11 43.0 1.8 4.7e-11 42.5 0.3 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KXZ41814.1 - 1e-08 34.2 0.1 2.9e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KXZ41814.1 - 2.7e-06 27.2 2.6 0.014 15.1 0.5 2.2 2 0 0 2 2 2 2 Syntaxin APG17 PF04108.12 KXZ41814.1 - 0.012 14.7 0.7 0.14 11.3 0.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF16 PF01519.16 KXZ41814.1 - 0.047 14.2 2.1 0.082 13.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 KXZ41814.1 - 0.084 13.3 2.8 5.7 7.4 0.0 2.9 3 1 0 3 3 3 0 Snapin/Pallidin FlxA PF14282.6 KXZ41814.1 - 0.11 12.5 3.8 0.14 12.1 0.2 2.5 2 1 0 2 2 2 0 FlxA-like protein IKBKB_SDD PF18397.1 KXZ41814.1 - 0.13 11.6 0.8 1.9 7.7 0.1 2.1 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain TBCA PF02970.16 KXZ41814.1 - 0.16 12.3 0.2 0.58 10.5 0.0 2.1 2 1 0 2 2 2 0 Tubulin binding cofactor A HemX PF04375.14 KXZ41814.1 - 0.17 11.1 8.4 0.57 9.4 2.7 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Syntaxin_2 PF14523.6 KXZ41814.1 - 0.24 11.8 7.1 0.37 11.2 0.8 3.0 3 0 0 3 3 3 0 Syntaxin-like protein Prominin PF05478.11 KXZ41814.1 - 0.29 9.1 1.3 2.1 6.2 0.1 2.0 2 0 0 2 2 2 0 Prominin DUF948 PF06103.11 KXZ41814.1 - 0.85 9.9 3.0 8.3 6.7 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Trypan_PARP PF05887.11 KXZ41815.1 - 0.0011 18.9 15.4 0.0025 17.8 15.4 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 KXZ41815.1 - 0.1 11.7 2.8 0.21 10.7 2.8 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Neisseria_TspB PF05616.13 KXZ41815.1 - 1.5 7.2 9.2 2.3 6.6 9.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PIN_4 PF13638.6 KXZ41816.1 - 0.0016 18.7 0.0 0.0034 17.7 0.0 1.5 1 1 0 1 1 1 1 PIN domain BUD22 PF09073.10 KXZ41816.1 - 0.16 11.3 7.8 0.24 10.7 7.8 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KXZ41816.1 - 1.8 6.7 11.9 2.5 6.2 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family MoCF_biosynth PF00994.24 KXZ41817.1 - 3.4e-21 75.4 0.1 4e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain UQ_con PF00179.26 KXZ41818.1 - 5.1e-50 168.8 0.0 5.8e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXZ41818.1 - 2.7e-05 23.9 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXZ41818.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KXZ41818.1 - 0.045 14.0 0.3 0.082 13.2 0.3 1.7 1 1 0 1 1 1 0 RWD domain Cpn60_TCP1 PF00118.24 KXZ41819.1 - 1.1e-154 515.7 0.3 1.2e-154 515.6 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Anthrax-tox_M PF09156.10 KXZ41819.1 - 0.14 11.5 0.2 0.29 10.4 0.2 1.5 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain SlyX PF04102.12 KXZ41820.1 - 0.078 13.6 0.4 0.33 11.6 0.0 2.3 2 0 0 2 2 2 0 SlyX Dam PF05869.11 KXZ41821.1 - 0.041 13.5 0.4 0.065 12.8 0.1 1.5 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) RVT_2 PF07727.14 KXZ41823.1 - 0.27 10.8 0.0 0.43 10.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 KXZ41824.1 - 2.9e-23 82.8 0.0 3.1e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Formyl_trans_N PF00551.19 KXZ41825.1 - 7.7e-25 87.7 0.0 1.8e-23 83.2 0.0 2.1 1 1 0 1 1 1 1 Formyl transferase ACT PF01842.25 KXZ41825.1 - 3.5e-07 29.9 0.0 9.1e-07 28.5 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KXZ41825.1 - 0.06 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 ACT domain Ribosomal_L37e PF01907.19 KXZ41826.1 - 1.3e-25 89.3 12.0 2.5e-25 88.4 12.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KXZ41826.1 - 0.023 14.7 2.0 0.037 14.1 2.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon SelR PF01641.18 KXZ41826.1 - 0.027 14.6 0.5 0.03 14.4 0.5 1.2 1 0 0 1 1 1 0 SelR domain DUF1462 PF07315.11 KXZ41826.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) zinc_ribbon_2 PF13240.6 KXZ41826.1 - 0.12 12.1 2.8 0.26 11.1 2.8 1.5 1 1 0 1 1 1 0 zinc-ribbon domain Viral_NABP PF05515.11 KXZ41826.1 - 0.14 12.0 3.8 0.18 11.6 3.8 1.2 1 0 0 1 1 1 0 Viral nucleic acid binding GATA PF00320.27 KXZ41826.1 - 0.14 11.8 5.9 15 5.3 4.9 2.6 1 1 1 2 2 2 0 GATA zinc finger Rubredoxin_2 PF18073.1 KXZ41826.1 - 0.16 11.7 4.3 1.1 9.0 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF1258 PF06869.12 KXZ41826.1 - 0.17 11.3 1.1 0.22 11.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) HypA PF01155.19 KXZ41826.1 - 0.19 11.8 1.4 0.26 11.3 1.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 KXZ41826.1 - 0.2 11.6 4.0 0.29 11.1 4.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF35_N PF12172.8 KXZ41826.1 - 0.22 11.4 4.3 0.43 10.5 4.3 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TF_Zn_Ribbon PF08271.12 KXZ41826.1 - 0.4 10.2 2.1 0.94 9.0 2.1 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding zf-Mss51 PF13824.6 KXZ41826.1 - 0.59 10.3 4.1 3.3 7.9 0.2 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Pkinase PF00069.25 KXZ41829.1 - 6.8e-32 110.9 0.0 5.7e-17 61.9 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41829.1 - 4.1e-26 91.8 0.0 2.8e-14 53.0 0.0 3.5 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KXZ41829.1 - 0.027 14.4 2.7 0.06 13.3 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family CN_hydrolase PF00795.22 KXZ41830.1 - 5.2e-06 26.0 0.0 7.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2275 PF10039.9 KXZ41830.1 - 0.17 12.0 0.2 0.38 10.8 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Pkinase PF00069.25 KXZ41831.1 - 1.6e-30 106.3 0.0 6.1e-30 104.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41831.1 - 4.6e-29 101.5 0.0 5.9e-24 84.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ41831.1 - 0.019 14.9 0.7 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ41831.1 - 0.056 12.2 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Roc PF08477.13 KXZ41833.1 - 3.4e-20 72.5 0.0 5.8e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ41833.1 - 3.6e-12 46.2 0.0 5.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Ras family COR PF16095.5 KXZ41833.1 - 4.9e-08 33.0 0.0 7.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Arf PF00025.21 KXZ41833.1 - 7.1e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXZ41833.1 - 0.0041 17.2 0.0 0.038 14.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KXZ41833.1 - 0.0055 17.2 0.0 0.16 12.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KXZ41833.1 - 0.0078 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXZ41833.1 - 0.0081 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KXZ41833.1 - 0.016 15.7 0.0 0.051 14.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 KXZ41833.1 - 0.035 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXZ41833.1 - 0.077 12.4 0.1 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXZ41833.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain HNH_repeat PF18780.1 KXZ41833.1 - 3.1 7.7 7.0 0.11 12.3 0.4 2.1 2 0 0 2 2 1 0 Homing endonuclease repeat Pox_A_type_inc PF04508.12 KXZ41834.1 - 0.012 15.4 8.8 0.04 13.8 1.4 5.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Alkyl_sulf_C PF14864.6 KXZ41834.1 - 8.1 6.7 12.2 0.074 13.3 0.9 3.6 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal Tic110 PF16940.5 KXZ41835.1 - 0.044 12.3 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter GRIP PF01465.20 KXZ41837.1 - 6.6e-08 32.3 0.2 2.9e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 GRIP domain CCDC144C PF14915.6 KXZ41837.1 - 0.0018 17.5 11.2 0.0018 17.5 11.2 10.4 5 3 2 9 9 9 1 CCDC144C protein coiled-coil region Pox_A_type_inc PF04508.12 KXZ41837.1 - 0.081 12.8 13.2 8.7 6.4 0.0 7.6 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat rve PF00665.26 KXZ41838.1 - 1.5e-10 41.3 0.1 4.4e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 KXZ41838.1 - 7.1e-07 29.0 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_S26 PF10502.9 KXZ41838.1 - 0.00045 20.0 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 rve_3 PF13683.6 KXZ41838.1 - 0.055 13.2 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain eIF-1a PF01176.19 KXZ41838.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Pkinase PF00069.25 KXZ41839.1 - 2.3e-06 27.2 0.0 4.5e-06 26.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41839.1 - 9.6e-06 25.1 0.0 3.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ41840.1 - 7.5e-41 140.1 0.0 1.3e-16 60.7 0.0 4.1 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ41840.1 - 2.3e-32 112.4 0.0 1.7e-11 44.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Kdo PF06293.14 KXZ41840.1 - 0.016 14.6 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ41840.1 - 0.64 9.9 4.6 0.28 11.1 0.4 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF1656 PF07869.12 KXZ41841.1 - 0.083 12.9 0.6 0.14 12.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF1761 PF08570.10 KXZ41842.1 - 0.011 16.0 1.2 0.016 15.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) CAP_N PF01213.19 KXZ41842.1 - 0.25 10.8 5.0 0.5 9.8 5.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Phage_holin_3_6 PF07332.11 KXZ41842.1 - 2.4 8.2 16.5 0.097 12.7 5.8 2.6 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Tic110 PF16940.5 KXZ41842.1 - 2.9 6.3 8.1 5 5.5 8.1 1.4 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF2721 PF11026.8 KXZ41842.1 - 5 7.0 11.9 27 4.7 11.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) SBF_like PF13593.6 KXZ41843.1 - 2.6e-37 128.8 15.9 3.1e-37 128.6 15.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 KXZ41843.1 - 0.28 9.5 11.8 0.028 12.8 3.5 2.5 1 1 2 3 3 3 0 Membrane transport protein Prismane PF03063.20 KXZ41844.1 - 4.8e-87 292.8 0.0 5.3e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family HPP PF04982.13 KXZ41845.1 - 3.8e-38 130.4 6.5 4.3e-38 130.2 6.5 1.0 1 0 0 1 1 1 1 HPP family Prismane PF03063.20 KXZ41847.1 - 3.3e-32 111.9 0.5 1.6e-20 73.3 0.2 2.0 2 0 0 2 2 2 2 Prismane/CO dehydrogenase family RcsF PF16358.5 KXZ41847.1 - 0.0014 18.7 1.1 0.0032 17.5 1.1 1.6 1 0 0 1 1 1 1 RcsF lipoprotein Glyco_transf_5 PF08323.11 KXZ41848.1 - 6.6e-16 58.7 0.0 9.4e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXZ41848.1 - 4e-06 26.5 0.0 9.8e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ41848.1 - 0.0019 18.6 0.0 0.0043 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_Tnp_ISL3 PF13542.6 KXZ41848.1 - 0.15 11.5 0.3 0.51 9.8 0.3 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 zf-NOSIP PF15906.5 KXZ41849.1 - 0.0076 16.4 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Flavi_DEAD PF07652.14 KXZ41849.1 - 0.037 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Flavivirus DEAD domain Toxin_13 PF07822.11 KXZ41849.1 - 0.19 11.9 0.1 0.19 11.9 0.1 1.7 2 0 0 2 2 2 0 Neurotoxin B-IV-like protein GTP_cyclohydroI PF01227.22 KXZ41850.1 - 1.3e-71 239.7 7.5 4.1e-45 153.4 0.0 4.2 4 0 0 4 4 4 4 GTP cyclohydrolase I Transglut_core PF01841.19 KXZ41851.1 - 1.2e-12 48.3 0.1 1.8e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily SET PF00856.28 KXZ41852.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 SET domain Ank_2 PF12796.7 KXZ41853.1 - 3.7e-07 30.6 0.6 0.007 16.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41853.1 - 4.4e-06 26.6 5.6 0.35 11.6 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KXZ41853.1 - 0.0001 22.6 8.7 1.9 9.1 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXZ41853.1 - 0.0013 19.3 1.3 0.5 11.0 0.2 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41853.1 - 0.15 12.4 6.1 33 5.0 0.5 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) tRNA_bind PF01588.20 KXZ41854.1 - 8e-31 106.0 0.2 1.3e-30 105.3 0.2 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KXZ41854.1 - 0.00021 21.4 0.1 0.00084 19.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ41854.1 - 0.0007 19.6 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXZ41854.1 - 0.001 19.3 0.3 0.0023 18.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXZ41854.1 - 0.076 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LSDAT_prok PF18171.1 KXZ41855.1 - 0.0011 18.2 0.1 0.0022 17.2 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote NYN PF01936.18 KXZ41855.1 - 0.0062 17.0 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 NYN domain FH2 PF02181.23 KXZ41855.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Helitron_like_N PF14214.6 KXZ41856.1 - 3e-22 79.8 0.2 5.5e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KXZ41857.1 - 6.6e-23 81.5 0.0 2.6e-22 79.5 0.0 1.8 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KXZ41857.1 - 4.5e-15 55.9 0.0 1.5e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Peptidase_C48 PF02902.19 KXZ41857.1 - 2.3e-08 34.1 0.0 4.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AAA_19 PF13245.6 KXZ41857.1 - 2.9e-07 30.9 0.0 6.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ41857.1 - 0.00045 20.5 0.0 0.0049 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KXZ41857.1 - 0.003 17.3 0.2 0.0083 15.9 0.2 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RsgA_GTPase PF03193.16 KXZ41857.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXZ41857.1 - 0.068 13.5 0.1 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.7 KXZ41861.1 - 2e-21 76.4 4.5 1.9e-14 54.0 1.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41861.1 - 1e-17 62.3 0.3 0.00042 20.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXZ41861.1 - 1.5e-16 60.5 2.6 3.9e-11 43.2 0.8 2.4 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ41861.1 - 3e-16 59.1 1.7 0.00061 20.1 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ41861.1 - 3.2e-12 46.4 8.0 3.5e-05 24.0 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) HEAT_2 PF13646.6 KXZ41861.1 - 0.0045 17.3 4.4 0.0084 16.5 4.1 1.6 1 1 1 2 2 2 1 HEAT repeats UBA PF00627.31 KXZ41861.1 - 0.014 15.3 3.7 6.7 6.7 0.1 3.2 3 0 0 3 3 3 0 UBA/TS-N domain YbjN PF10722.9 KXZ41861.1 - 0.014 15.4 0.0 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator ERAP1_C PF11838.8 KXZ41861.1 - 0.059 12.9 2.4 0.11 12.1 2.4 1.4 1 1 0 1 1 1 0 ERAP1-like C-terminal domain VPS9 PF02204.18 KXZ41861.1 - 0.17 12.1 0.3 22 5.3 0.0 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain COR PF16095.5 KXZ41862.1 - 1.6e-16 60.7 0.0 3.7e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Phage_30_8 PF06019.11 KXZ41862.1 - 0.013 15.4 0.2 8.8 6.3 0.0 2.7 2 1 0 2 2 2 0 Phage GP30.8 protein PHD PF00628.29 KXZ41863.1 - 1.1e-07 31.7 9.1 2.6e-07 30.4 9.1 1.7 1 0 0 1 1 1 1 PHD-finger Tropomyosin_1 PF12718.7 KXZ41863.1 - 0.0061 16.7 5.5 0.0061 16.7 5.5 1.8 2 0 0 2 2 2 1 Tropomyosin like CENP-Q PF13094.6 KXZ41863.1 - 0.027 14.7 7.6 0.08 13.1 7.6 1.8 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.11 KXZ41863.1 - 0.56 10.8 3.6 1.5 9.5 3.6 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF3103 PF11301.8 KXZ41863.1 - 0.59 8.9 4.8 1.2 7.8 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) YabA PF06156.13 KXZ41863.1 - 1.3 9.7 3.5 4 8.1 3.5 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Cnn_1N PF07989.11 KXZ41863.1 - 2.3 8.4 5.3 4.6 7.5 5.3 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 KXZ41863.1 - 2.4 7.2 8.0 4.3 6.3 8.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KXZ41863.1 - 2.7 8.1 9.0 4.2 7.4 9.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Dam PF05869.11 KXZ41865.1 - 3e-09 36.7 0.0 4.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) COR PF16095.5 KXZ41866.1 - 4.5e-18 65.8 0.0 5.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain HOIP-UBA PF16678.5 KXZ41866.1 - 0.18 11.8 0.3 19 5.3 0.0 2.4 2 0 0 2 2 2 0 HOIP UBA domain pair HSBP1 PF06825.12 KXZ41867.1 - 0.068 13.0 1.6 1.1 9.1 1.1 2.2 1 1 1 2 2 2 0 Heat shock factor binding protein 1 DUF3552 PF12072.8 KXZ41867.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) COR PF16095.5 KXZ41868.1 - 1e-12 48.3 0.0 1.4e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_4 PF13637.6 KXZ41873.1 - 0.00037 21.0 0.1 26 5.6 0.1 4.8 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41873.1 - 0.0041 17.5 0.1 68 4.5 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Iso_dh PF00180.20 KXZ41875.1 - 1.3e-40 139.6 0.0 1.7e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_10 PF00331.20 KXZ41876.1 - 2.8e-27 95.7 0.0 4.1e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 FAA_hydrolase PF01557.18 KXZ41877.1 - 3.5e-40 138.0 0.0 1e-39 136.5 0.0 1.6 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF953 PF06110.11 KXZ41878.1 - 4e-07 29.7 0.1 6.3e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Tubulin PF00091.25 KXZ41879.1 - 2.1e-36 126.0 0.0 2.4e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 KXZ41879.1 - 1.6e-05 25.2 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF4476 PF14771.6 KXZ41880.1 - 0.0002 21.6 0.0 0.98 9.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4476) IQ PF00612.27 KXZ41880.1 - 0.00025 20.5 2.2 0.00094 18.8 2.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_6 PF13516.6 KXZ41881.1 - 1.8e-14 52.4 13.6 0.00039 20.2 0.3 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KXZ41881.1 - 5.3e-05 23.2 0.9 7.6 7.5 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.6 KXZ41881.1 - 0.0023 17.7 5.6 0.65 9.8 0.0 3.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KXZ41881.1 - 0.099 13.1 8.8 6 7.4 1.1 4.1 2 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 KXZ41882.1 - 5.8e-21 74.9 0.1 6.9e-07 29.8 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41882.1 - 2.2e-14 53.6 2.1 0.00034 21.1 0.0 4.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41882.1 - 4.2e-14 52.4 4.4 8.8e-05 22.7 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41882.1 - 1e-13 50.1 0.6 0.051 14.1 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KXZ41882.1 - 3.5e-10 39.8 0.8 0.2 12.2 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat PDZ_3 PF17815.1 KXZ41883.1 - 1.9e-46 157.6 0.0 2.7e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KXZ41883.1 - 5.1e-23 82.6 8.8 9.7e-23 81.7 4.1 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXZ41883.1 - 3.2e-17 63.1 0.1 5.4e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Trypsin Hydrolase_6 PF13344.6 KXZ41884.1 - 4.7e-14 52.3 0.0 1.3e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ41884.1 - 1e-12 47.9 0.1 3.1e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXZ41884.1 - 0.086 13.1 2.8 0.24 11.6 0.0 2.9 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase AF-4 PF05110.13 KXZ41884.1 - 5.7 4.9 7.9 7.7 4.5 7.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cupin_3 PF05899.12 KXZ41886.1 - 2.2e-31 107.3 0.3 2.8e-31 107.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KXZ41886.1 - 9.9e-08 31.6 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KXZ41886.1 - 0.00017 21.3 0.1 0.00023 21.0 0.1 1.2 1 0 0 1 1 1 1 Cupin EutQ PF06249.12 KXZ41886.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ zf-C2H2_11 PF16622.5 KXZ41887.1 - 0.0036 17.0 0.4 0.0061 16.3 0.4 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KXZ41887.1 - 0.075 13.9 0.1 0.13 13.2 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXZ41887.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Creb_binding PF09030.10 KXZ41888.1 - 0.17 12.6 0.0 0.24 12.1 0.0 1.3 1 0 0 1 1 1 0 Creb binding G-patch PF01585.23 KXZ41892.1 - 1.1e-07 31.6 0.7 2.6e-07 30.4 0.7 1.7 1 0 0 1 1 1 1 G-patch domain SR-25 PF10500.9 KXZ41892.1 - 0.12 11.9 37.0 0.21 11.2 37.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 KXZ41892.1 - 1.9 7.3 17.1 2.6 6.8 17.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 KXZ41892.1 - 1.9 8.2 11.0 3.5 7.4 11.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 KXZ41892.1 - 2.3 5.2 6.3 3.2 4.7 6.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4614 PF15391.6 KXZ41892.1 - 2.4 8.1 15.7 7 6.6 15.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PI3K_1B_p101 PF10486.9 KXZ41892.1 - 2.6 5.7 8.8 3.6 5.2 8.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM76 PF16046.5 KXZ41892.1 - 7 5.9 15.8 11 5.2 15.8 1.2 1 0 0 1 1 1 0 FAM76 protein Rrn6 PF10214.9 KXZ41892.1 - 8 4.8 24.2 18 3.7 24.2 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SLC12 PF03522.15 KXZ41892.1 - 8.7 5.2 9.0 12 4.8 9.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 KXZ41892.1 - 8.8 4.5 29.3 14 3.8 29.3 1.2 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 KXZ41892.1 - 9.4 4.9 6.0 13 4.5 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 KXZ41892.1 - 9.7 4.8 15.6 16 4.1 15.6 1.3 1 0 0 1 1 1 0 Presenilin MMR_HSR1 PF01926.23 KXZ41893.1 - 1.2e-11 44.7 0.0 3.8e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXZ41893.1 - 0.00055 20.4 3.5 0.00078 19.9 0.0 2.6 2 2 1 3 3 3 1 AAA ATPase domain FeoB_N PF02421.18 KXZ41893.1 - 0.0015 18.1 0.4 0.021 14.4 0.1 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXZ41893.1 - 0.0096 15.5 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KXZ41893.1 - 0.017 15.7 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXZ41893.1 - 0.038 13.9 0.1 0.19 11.6 0.1 2.2 1 1 0 1 1 1 0 RsgA GTPase TniB PF05621.11 KXZ41893.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 KXZ41893.1 - 0.077 13.1 0.1 1.6 8.8 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 KXZ41893.1 - 0.14 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 KXZ41893.1 - 0.24 10.8 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AIG1 PF04548.16 KXZ41893.1 - 0.28 10.5 0.0 0.68 9.2 0.0 1.5 2 0 0 2 2 2 0 AIG1 family AAA PF00004.29 KXZ41894.1 - 3.4e-35 121.3 0.0 4.8e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ41894.1 - 3e-07 30.5 0.3 3.3e-06 27.1 0.1 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXZ41894.1 - 3.2e-07 30.2 0.0 8.5e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ41894.1 - 9.7e-07 29.3 0.1 6.5e-05 23.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXZ41894.1 - 1.6e-05 25.2 0.1 0.00037 20.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXZ41894.1 - 1.9e-05 24.5 0.0 3.2e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KXZ41894.1 - 2.9e-05 23.5 0.0 6.9e-05 22.2 0.0 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 KXZ41894.1 - 8.6e-05 23.1 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ41894.1 - 0.00024 21.3 0.0 0.00075 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXZ41894.1 - 0.00029 20.4 0.1 0.00068 19.2 0.0 1.7 2 1 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXZ41894.1 - 0.00047 19.6 0.1 0.0014 18.1 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXZ41894.1 - 0.0011 18.6 0.3 0.0036 16.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXZ41894.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXZ41894.1 - 0.0017 18.7 0.0 0.0056 17.1 0.0 1.9 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 KXZ41894.1 - 0.0024 17.8 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Parvo_NS1 PF01057.17 KXZ41894.1 - 0.0047 16.1 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KXZ41894.1 - 0.0054 17.0 0.1 0.012 15.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 KXZ41894.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KXZ41894.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KXZ41894.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 KXZ41894.1 - 0.024 14.3 0.0 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KXZ41894.1 - 0.024 14.7 0.0 0.065 13.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KXZ41894.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXZ41894.1 - 0.043 13.2 0.0 0.64 9.4 0.0 2.2 1 1 0 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 KXZ41894.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXZ41894.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXZ41894.1 - 0.051 14.0 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXZ41894.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF815 PF05673.13 KXZ41894.1 - 0.063 12.4 0.0 0.098 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_6 PF12774.7 KXZ41894.1 - 0.11 11.5 0.2 0.53 9.2 0.1 2.0 1 1 1 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AFG1_ATPase PF03969.16 KXZ41894.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase AAA_11 PF13086.6 KXZ41894.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ41894.1 - 0.21 12.1 0.0 0.54 10.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Acetyltransf_1 PF00583.25 KXZ41895.1 - 6.8e-11 42.4 0.0 1.2e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ41895.1 - 1.9e-09 37.5 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ41895.1 - 6e-09 36.2 0.0 1.3e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ41895.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KXZ41895.1 - 0.0011 18.7 0.2 0.0017 18.1 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KXZ41895.1 - 0.003 17.6 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXZ41895.1 - 0.069 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Histone_H2A_C PF16211.5 KXZ41896.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ41896.1 - 6.3e-17 62.2 0.0 8.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ41896.1 - 3.4e-05 24.0 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ41897.1 - 2.2e-22 79.8 5.8 2.8e-22 79.5 5.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ41897.1 - 8.2e-05 22.8 0.1 8.2e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ41897.1 - 0.0019 18.6 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ41897.1 - 0.016 14.9 0.3 0.76 9.4 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ41897.1 - 0.028 14.4 5.3 0.055 13.5 5.3 1.5 1 1 0 1 1 1 0 YscO-like protein DUF3391 PF11871.8 KXZ41897.1 - 2.9 8.4 10.3 9.2 6.8 10.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) AA_permease_2 PF13520.6 KXZ41898.1 - 1.1e-41 143.0 36.4 1.5e-41 142.6 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXZ41898.1 - 3.9e-05 22.4 34.3 9e-05 21.2 34.3 1.6 1 1 0 1 1 1 1 Amino acid permease WD40 PF00400.32 KXZ41899.1 - 9.1e-36 121.3 13.1 1.9e-08 34.8 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ41899.1 - 1.2e-07 31.9 0.0 0.025 14.9 0.0 4.2 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXZ41899.1 - 0.013 15.1 0.5 0.036 13.6 0.0 2.0 2 1 0 2 2 2 0 PQQ-like domain VID27 PF08553.10 KXZ41899.1 - 0.033 13.2 0.1 0.22 10.5 0.1 2.0 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Cytotoxic PF09000.10 KXZ41899.1 - 0.11 12.8 0.4 0.43 11.0 0.2 2.1 1 1 1 2 2 2 0 Cytotoxic Dpy-30 PF05186.13 KXZ41902.1 - 1.2e-05 24.9 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif DUF5582 PF17819.1 KXZ41902.1 - 0.0075 16.7 0.0 0.0077 16.7 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 KXZ41902.1 - 0.02 14.0 0.0 0.023 13.8 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5586) RIIa PF02197.17 KXZ41902.1 - 0.033 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit WD40 PF00400.32 KXZ41903.1 - 4.2e-10 40.1 6.7 0.0013 19.5 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat POT1 PF02765.17 KXZ41906.1 - 7.7e-06 25.8 0.0 4.9e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 KXZ41906.1 - 0.0051 16.7 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein TPR_1 PF00515.28 KXZ41907.1 - 1.5e-78 255.6 23.4 1.9e-07 30.6 0.2 14.1 14 0 0 14 14 14 12 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ41907.1 - 1.1e-71 231.3 33.0 2.7e-06 27.0 0.3 14.2 14 0 0 14 14 14 12 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ41907.1 - 3.4e-60 199.5 25.9 1.5e-06 27.7 0.0 13.4 4 4 9 13 13 13 11 TPR repeat TPR_17 PF13431.6 KXZ41907.1 - 1.8e-53 175.2 15.4 2.6e-05 24.3 0.1 13.6 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ41907.1 - 6.3e-50 163.3 3.9 0.00056 19.9 0.0 12.6 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ41907.1 - 6.8e-42 141.5 36.8 9.7e-07 28.9 0.9 10.5 3 2 7 10 10 10 10 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ41907.1 - 7e-42 141.8 65.9 3.1e-08 34.1 3.9 11.5 4 3 6 11 11 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ41907.1 - 3.3e-30 104.2 34.0 3.7e-06 27.1 1.9 9.2 3 2 8 11 11 11 10 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ41907.1 - 7e-23 78.9 26.2 0.0083 16.1 0.0 12.6 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ41907.1 - 1.7e-20 73.3 37.0 5.3e-05 23.6 0.9 11.0 7 3 4 11 11 11 9 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ41907.1 - 1.4e-15 56.6 61.9 0.0023 18.6 0.5 14.7 5 4 11 16 16 13 7 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ41907.1 - 3.2e-15 55.7 24.4 0.058 14.1 0.0 12.5 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ41907.1 - 7.8e-09 35.1 9.2 0.86 8.8 0.0 7.1 2 1 3 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ41907.1 - 1.6e-07 31.4 11.9 0.056 13.7 0.1 4.4 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 KXZ41907.1 - 2.5e-06 26.9 13.6 3.8 7.1 0.0 9.5 10 1 0 10 10 10 1 SHNi-TPR TPR_10 PF13374.6 KXZ41907.1 - 0.00015 21.5 48.3 0.0049 16.7 1.7 11.0 12 0 0 12 12 12 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ41907.1 - 0.006 16.6 7.5 28 4.9 0.0 6.6 6 2 2 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 KXZ41907.1 - 0.0088 16.1 6.0 10 6.2 0.2 5.9 5 1 2 7 7 6 0 Domain of Unknown Function (DUF3856) TOM20_plant PF06552.12 KXZ41907.1 - 0.053 13.3 0.4 1.4 8.6 0.1 3.1 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF3808 PF10300.9 KXZ41907.1 - 0.16 10.6 0.0 0.37 9.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) HrpB1_HrpK PF09613.10 KXZ41907.1 - 0.95 9.1 6.8 3.5 7.3 0.0 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Pkinase PF00069.25 KXZ41908.1 - 2.3e-21 76.4 0.0 3.2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41908.1 - 7.2e-18 64.8 0.0 9.2e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ41909.1 - 0.0003 20.2 2.6 0.51 9.7 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ41909.1 - 0.00038 19.8 4.7 2.6 7.3 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase BON PF04972.17 KXZ41909.1 - 0.061 13.6 0.0 19 5.7 0.0 2.4 2 0 0 2 2 2 0 BON domain Roc PF08477.13 KXZ41912.1 - 7.2e-10 39.1 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ41912.1 - 1.3e-06 28.2 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ras family COR PF16095.5 KXZ41912.1 - 4.8e-06 26.5 0.0 9.1e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Arf PF00025.21 KXZ41912.1 - 0.00017 21.1 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Mg_chelatase PF01078.21 KXZ41912.1 - 0.0031 16.9 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXZ41912.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KXZ41912.1 - 0.058 13.8 0.1 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.12 KXZ41912.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXZ41912.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KXZ41912.1 - 0.19 12.3 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter bVLRF1 PF18826.1 KXZ41914.1 - 5.2e-16 58.9 0.0 9.5e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Aldo_ket_red PF00248.21 KXZ41915.1 - 4.2e-20 72.1 0.0 4.9e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 KXZ41916.1 - 4e-07 30.5 0.0 0.00094 19.7 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ41916.1 - 0.00015 22.2 0.2 1.3 9.7 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ41916.1 - 0.00043 20.5 0.0 13 6.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ41916.1 - 0.038 14.5 0.0 4.4 8.2 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Bax1-I PF01027.20 KXZ41918.1 - 5.7e-37 127.6 25.3 6.5e-37 127.4 25.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KXZ41918.1 - 0.0016 18.0 19.3 0.0022 17.6 19.3 1.1 1 0 0 1 1 1 1 Bax inhibitor 1 like Orai-1 PF07856.12 KXZ41918.1 - 0.3 10.7 8.9 2.5 7.8 4.7 2.4 1 1 1 2 2 2 0 Mediator of CRAC channel activity PI3Ka PF00613.20 KXZ41919.1 - 1.6e-51 174.4 0.3 1.3e-50 171.4 0.2 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KXZ41919.1 - 8.4e-45 153.5 0.1 6e-32 111.4 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KXZ41919.1 - 2.4e-20 72.9 0.0 3.8e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 HEAT_2 PF13646.6 KXZ41919.1 - 0.017 15.5 5.6 0.024 15.0 2.9 2.7 2 0 0 2 2 2 0 HEAT repeats ADH_zinc_N PF00107.26 KXZ41920.1 - 3.2e-15 56.3 0.3 5.6e-15 55.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXZ41920.1 - 8.1e-08 33.4 0.0 1.7e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXZ41920.1 - 1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.13 KXZ41920.1 - 0.022 14.3 0.5 0.039 13.5 0.4 1.4 2 0 0 2 2 2 0 NmrA-like family Acetyltransf_6 PF13480.7 KXZ41920.1 - 0.073 13.2 2.5 0.22 11.7 1.8 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Slu7 PF11708.8 KXZ41921.1 - 0.026 14.3 0.2 0.034 13.9 0.2 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF4599 PF15371.6 KXZ41921.1 - 0.042 14.4 2.6 0.064 13.8 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) DUF4577 PF15145.6 KXZ41922.1 - 0.012 15.7 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DHHC PF01529.20 KXZ41922.1 - 0.053 13.6 0.1 0.085 13.0 0.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase H_PPase PF03030.16 KXZ41922.1 - 0.36 9.4 3.1 0.49 9.0 3.1 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Ank_2 PF12796.7 KXZ41923.1 - 1.5e-08 35.1 0.0 0.0049 17.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ41923.1 - 0.0065 16.9 0.0 54 4.8 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 KXZ41923.1 - 0.011 16.3 0.0 3.5 8.3 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) NOA36 PF06524.12 KXZ41923.1 - 4.6 6.5 8.6 8.5 5.6 8.6 1.3 1 0 0 1 1 1 0 NOA36 protein ABC_tran PF00005.27 KXZ41925.1 - 2.6e-08 34.5 0.0 3.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ41925.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TPP_enzyme_N PF02776.18 KXZ41927.1 - 2.4e-21 76.1 0.9 1.2e-20 73.9 0.9 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CCDC-167 PF15188.6 KXZ41928.1 - 0.13 12.6 9.5 0.2 12.0 9.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PsbU PF06514.11 KXZ41928.1 - 0.15 12.1 0.3 0.24 11.4 0.3 1.4 1 1 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) DUF3552 PF12072.8 KXZ41929.1 - 0.032 13.6 11.1 0.035 13.5 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CCDC-167 PF15188.6 KXZ41929.1 - 0.11 12.8 11.0 0.13 12.6 11.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 FlxA PF14282.6 KXZ41930.1 - 0.042 13.8 6.7 0.087 12.8 6.7 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF2884 PF11101.8 KXZ41930.1 - 0.11 12.0 4.5 0.22 11.0 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3584 PF12128.8 KXZ41930.1 - 0.24 8.9 7.5 0.33 8.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC-167 PF15188.6 KXZ41930.1 - 0.5 10.7 13.6 1.1 9.7 13.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 REC1 PF18501.1 KXZ41930.1 - 0.61 9.9 5.7 0.95 9.3 5.7 1.2 1 0 0 1 1 1 0 Alpha helical recognition lobe domain APG6_N PF17675.1 KXZ41930.1 - 2.3 8.7 19.5 4.6 7.8 19.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3552 PF12072.8 KXZ41930.1 - 3.6 6.9 16.4 6.2 6.2 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PGA2 PF07543.12 KXZ41932.1 - 5.2 7.1 6.5 1.7 8.6 1.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Prok-RING_4 PF14447.6 KXZ41932.1 - 6.7 6.7 11.4 19 5.2 11.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 SPT6_acidic PF14632.6 KXZ41932.1 - 8.7 7.0 9.2 1.2 9.8 1.8 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 zf-RING_2 PF13639.6 KXZ41932.1 - 9.3 6.7 13.2 21 5.6 13.2 1.6 1 0 0 1 1 1 0 Ring finger domain SWIM PF04434.17 KXZ41933.1 - 2.4e-06 27.1 0.4 2.4e-06 27.1 0.4 1.6 2 0 0 2 2 2 1 SWIM zinc finger dUTPase PF00692.19 KXZ41934.1 - 1.1e-43 148.0 0.0 1.4e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KXZ41934.1 - 0.03 13.1 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DUF2838 PF10998.8 KXZ41935.1 - 1.1e-05 25.7 1.7 1.5e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Peptidase_M48 PF01435.18 KXZ41936.1 - 0.00016 21.6 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 GATase PF00117.28 KXZ41937.1 - 2.8e-54 183.8 0.0 3.2e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXZ41937.1 - 1.4e-11 44.6 0.3 3.3e-11 43.4 0.3 1.6 1 1 0 1 1 1 1 Peptidase C26 DHBP_synthase PF00926.19 KXZ41938.1 - 4e-81 271.2 0.0 5.3e-81 270.7 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 KXZ41938.1 - 3.7e-20 72.1 0.0 6.8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Gpr1_Fun34_YaaH PF01184.19 KXZ41939.1 - 9e-32 110.4 19.7 1.2e-31 109.9 19.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4560 PF15118.6 KXZ41939.1 - 0.21 11.5 2.5 0.51 10.3 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4560) Gpr1_Fun34_YaaH PF01184.19 KXZ41940.1 - 4.4e-27 95.0 17.2 6.7e-27 94.4 17.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family P_proprotein PF01483.20 KXZ41943.1 - 2.6e-09 37.0 0.1 1e-07 31.9 0.1 2.3 1 1 0 1 1 1 1 Proprotein convertase P-domain PMG PF05287.12 KXZ41943.1 - 0.042 13.9 1.6 0.08 13.0 1.6 1.4 1 0 0 1 1 1 0 PMG protein SRF-TF PF00319.18 KXZ41944.1 - 1.6e-11 43.5 0.0 2.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SAP PF02037.27 KXZ41945.1 - 0.00012 21.7 0.6 0.00017 21.2 0.6 1.2 1 0 0 1 1 1 1 SAP domain SPX PF03105.19 KXZ41946.1 - 0.46 10.3 3.4 1.1 9.1 3.4 1.6 1 0 0 1 1 1 0 SPX domain Mito_carr PF00153.27 KXZ41947.1 - 1.9e-20 72.5 5.4 7.7e-08 32.2 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3040 PF11239.8 KXZ41949.1 - 0.93 9.8 9.2 4.7 7.5 0.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) FAM184 PF15665.5 KXZ41951.1 - 0.023 14.5 0.0 0.023 14.5 0.0 4.8 3 1 0 4 4 4 0 Family with sequence similarity 184, A and B NPV_P10 PF05531.12 KXZ41951.1 - 0.065 13.7 5.4 12 6.5 0.1 4.4 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF2462 PF09495.10 KXZ41952.1 - 4.8e-11 43.2 14.4 4.8e-11 43.2 14.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Spc7 PF08317.11 KXZ41954.1 - 0.0054 15.6 22.0 0.051 12.5 10.4 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein BRE1 PF08647.11 KXZ41954.1 - 0.038 14.1 0.3 0.038 14.1 0.3 3.1 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Sec2p PF06428.11 KXZ41954.1 - 0.039 13.9 1.9 0.039 13.9 1.9 3.8 3 1 1 4 4 4 0 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.8 KXZ41954.1 - 0.13 12.2 12.2 2.6 8.1 1.1 3.7 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KXZ41954.1 - 0.17 12.0 14.8 0.59 10.2 5.8 2.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 KXZ41954.1 - 0.2 12.1 21.8 0.27 11.6 2.1 2.9 1 1 1 2 2 2 0 Fez1 KASH_CCD PF14662.6 KXZ41954.1 - 0.45 10.3 13.0 0.056 13.3 0.9 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KXZ41954.1 - 0.49 9.7 16.2 0.33 10.3 1.2 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KXZ41954.1 - 1.8 8.6 17.4 3.6 7.6 0.3 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cortex-I_coil PF09304.10 KXZ41954.1 - 2.7 8.3 20.2 2.9 8.1 2.4 3.9 1 1 3 4 4 4 0 Cortexillin I, coiled coil Leu_zip PF15294.6 KXZ41954.1 - 3.3 7.2 11.6 1.1 8.7 3.0 2.2 1 1 1 2 2 2 0 Leucine zipper ATG16 PF08614.11 KXZ41954.1 - 5.2 7.2 34.0 43 4.2 13.2 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 KXZ41954.1 - 5.4 6.0 20.5 7.3 5.6 11.3 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 KXZ41954.1 - 7.9 6.9 19.4 6 7.3 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GFO_IDH_MocA PF01408.22 KXZ41955.1 - 1.1e-11 45.6 0.1 2.1e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sec20 PF03908.13 KXZ41957.1 - 5e-18 64.8 0.2 8.1e-18 64.1 0.2 1.3 1 0 0 1 1 1 1 Sec20 Secretin_N PF03958.17 KXZ41958.1 - 0.026 14.9 3.6 0.15 12.5 0.0 4.0 3 2 0 3 3 3 0 Bacterial type II/III secretion system short domain MBOAT_2 PF13813.6 KXZ41959.1 - 7.7e-12 45.3 2.0 1.3e-11 44.6 1.0 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family HgmA PF04209.13 KXZ41960.1 - 5.1e-195 648.1 0.0 5.8e-195 648.0 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Sec23_trunk PF04811.15 KXZ41961.1 - 9e-73 244.8 0.0 1.2e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KXZ41961.1 - 4.7e-18 65.7 0.0 8.2e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXZ41961.1 - 6.1e-16 58.2 4.0 1.2e-15 57.3 4.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger IF-2 PF11987.8 KXZ41962.1 - 1.1e-10 41.6 0.0 1.9e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KXZ41962.1 - 0.0032 17.8 0.6 0.033 14.6 0.6 2.5 1 1 0 1 1 1 1 Elongation factor Tu domain 2 FTCD_C PF04961.12 KXZ41962.1 - 0.049 13.4 0.3 0.049 13.4 0.3 1.9 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase Hydrolase_like PF13242.6 KXZ41962.1 - 0.067 13.3 1.3 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 HAD-hyrolase-like C6_DPF PF10170.9 KXZ41963.1 - 8.6e-22 77.3 0.7 1e-21 77.1 0.7 1.1 1 0 0 1 1 1 1 Cysteine-rich domain ADK PF00406.22 KXZ41967.1 - 3.3e-38 131.1 0.0 5.1e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXZ41967.1 - 9.9e-19 68.1 0.5 1.4e-18 67.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXZ41967.1 - 0.00012 22.3 0.0 0.00079 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXZ41967.1 - 0.013 15.9 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ADK_lid PF05191.14 KXZ41967.1 - 0.025 14.5 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA_5 PF07728.14 KXZ41967.1 - 0.097 12.7 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 KXZ41967.1 - 0.11 12.2 0.8 0.16 11.7 0.1 1.5 2 0 0 2 2 2 0 Cytidylate kinase CoA_transf_3 PF02515.17 KXZ41968.1 - 4.9e-84 282.6 0.0 6.2e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Phage_integrase PF00589.22 KXZ41969.1 - 0.0062 16.3 0.0 0.0062 16.3 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF3435 PF11917.8 KXZ41969.1 - 0.07 12.0 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) RGP PF03214.13 KXZ41971.1 - 8.7e-133 442.7 0.0 9.8e-133 442.5 0.0 1.0 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide DUF1899 PF08953.11 KXZ41974.1 - 0.014 15.3 0.2 0.024 14.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) SET PF00856.28 KXZ41976.1 - 2.1e-06 28.3 0.0 1.4e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 SET domain PRP38_assoc PF12871.7 KXZ41977.1 - 0.12 13.0 10.4 0.15 12.7 10.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PGA2 PF07543.12 KXZ41977.1 - 0.18 11.8 9.9 0.21 11.5 9.9 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Cwf_Cwc_15 PF04889.12 KXZ41977.1 - 0.37 10.5 7.4 0.46 10.2 7.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KXZ41977.1 - 0.68 9.2 11.8 0.81 9.0 11.8 1.1 1 0 0 1 1 1 0 NOA36 protein SspB PF04386.13 KXZ41977.1 - 1.5 8.7 3.6 1.5 8.7 3.6 1.1 1 0 0 1 1 1 0 Stringent starvation protein B DNA_pol_phi PF04931.13 KXZ41977.1 - 3.1 5.8 12.9 3.5 5.6 12.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 KXZ41977.1 - 3.4 7.3 17.7 4 7.1 17.7 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.9 KXZ41977.1 - 6.6 5.7 14.2 8.8 5.3 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KXZ41977.1 - 8.5 4.5 8.9 9.5 4.4 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein ANAPC15 PF15243.6 KXZ41977.1 - 9.3 6.7 13.6 4.6 7.7 4.2 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 PGK PF00162.19 KXZ41979.1 - 6e-165 548.8 0.0 7.5e-165 548.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase VIR_N PF15912.5 KXZ41982.1 - 0.0015 18.2 3.0 0.027 14.1 0.0 2.4 2 0 0 2 2 2 1 Virilizer, N-terminal Transformer PF06495.11 KXZ41982.1 - 0.13 12.4 10.1 0.32 11.1 10.1 1.6 1 0 0 1 1 1 0 Fruit fly transformer protein DUF3915 PF13054.6 KXZ41982.1 - 3.7 7.6 7.5 7.4 6.6 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Herpes_UL25 PF01499.16 KXZ41983.1 - 3.3 6.1 5.8 4.6 5.6 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family TFIIA PF03153.13 KXZ41985.1 - 1.3 9.0 5.7 1.6 8.7 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Retrotrans_gag PF03732.17 KXZ41987.1 - 0.0078 16.5 1.1 0.12 12.6 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF5304 PF17230.2 KXZ41988.1 - 0.0007 19.9 0.2 0.00072 19.8 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5304) TetR_N PF00440.23 KXZ41988.1 - 0.037 13.8 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DUF4916 PF16262.5 KXZ41989.1 - 0.065 12.7 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) DUF5474 PF17568.2 KXZ41989.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5474) Aminotran_5 PF00266.19 KXZ41990.1 - 4.8e-41 140.9 0.0 1.2e-34 119.9 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXZ41990.1 - 0.0049 15.5 0.0 0.0082 14.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Lipase_GDSL_2 PF13472.6 KXZ41990.1 - 0.013 15.9 0.4 0.032 14.6 0.0 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF962 PF06127.11 KXZ41991.1 - 1.5e-22 79.5 4.3 6.5e-22 77.4 4.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) MatE PF01554.18 KXZ41992.1 - 2.1e-53 180.2 17.0 1.3e-26 93.1 6.0 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ41992.1 - 0.011 15.8 0.7 0.011 15.8 0.7 3.9 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain CD225 PF04505.12 KXZ41992.1 - 1.7 8.9 9.8 0.97 9.6 1.8 2.9 2 0 0 2 2 2 0 Interferon-induced transmembrane protein RRM_1 PF00076.22 KXZ41993.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Menin PF05053.13 KXZ41993.1 - 2.3 6.5 8.2 3.6 5.8 8.2 1.2 1 0 0 1 1 1 0 Menin TFIIA PF03153.13 KXZ41993.1 - 6.7 6.6 22.3 0.15 12.1 15.0 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit stn_TNFRSF12A PF12191.8 KXZ41995.1 - 0.026 14.8 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain stn_TNFRSF12A PF12191.8 KXZ41996.1 - 0.054 13.7 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain U-box PF04564.15 KXZ41998.1 - 1.4e-12 47.6 0.1 2.4e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 U-box domain Lebercilin PF15619.6 KXZ41999.1 - 0.00072 19.3 30.6 0.00092 18.9 28.3 2.0 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 KXZ41999.1 - 0.0078 16.7 11.4 0.0078 16.7 11.4 2.3 1 1 1 2 2 2 1 Apg6 coiled-coil region DUF148 PF02520.17 KXZ41999.1 - 0.032 14.4 2.0 0.058 13.5 1.3 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF148 GAS PF13851.6 KXZ41999.1 - 2.3 7.5 31.5 1.6 8.1 22.5 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DEAD PF00270.29 KXZ42000.1 - 1.7e-32 112.6 0.0 2.5e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ42000.1 - 3.4e-20 72.5 0.0 1.5e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ42000.1 - 0.00014 21.9 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXZ42000.1 - 0.0043 17.4 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KXZ42000.1 - 0.092 12.2 1.9 0.35 10.4 0.2 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TIR_2 PF13676.6 KXZ42000.1 - 0.2 12.3 0.0 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 TIR domain CAF1 PF04857.20 KXZ42003.1 - 7.2e-71 239.0 0.0 9.6e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KXZ42003.1 - 0.14 11.9 0.0 21 4.8 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease FAM221 PF14753.6 KXZ42004.1 - 6.7e-27 94.3 7.7 8.8e-15 54.8 1.9 2.1 2 0 0 2 2 2 2 Protein FAM221A/B Ank_2 PF12796.7 KXZ42005.1 - 6.3e-06 26.7 2.0 2.6 8.7 0.1 4.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ42005.1 - 2.1e-05 24.7 6.7 0.68 10.3 0.0 6.1 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ42005.1 - 0.0012 19.4 11.0 12 6.6 0.1 6.5 6 3 2 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42005.1 - 0.011 16.1 6.6 5.8 7.8 0.0 6.4 8 1 0 8 8 8 0 Ankyrin repeat rve PF00665.26 KXZ42009.1 - 8.7e-07 29.1 0.0 9.2e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain RR_TM4-6 PF06459.12 KXZ42011.1 - 0.09 12.6 0.9 0.12 12.2 0.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Chloroa_b-bind PF00504.21 KXZ42012.1 - 9.6e-46 156.3 0.0 1.2e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Cob_adeno_trans PF01923.18 KXZ42012.1 - 0.2 11.8 0.1 0.35 11.0 0.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Ank_4 PF13637.6 KXZ42013.1 - 8.4e-06 26.2 3.5 1 10.1 0.0 5.0 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42013.1 - 5e-05 23.8 0.0 0.0069 16.9 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42013.1 - 0.0019 18.5 0.4 18 6.3 0.0 5.4 4 1 2 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 KXZ42013.1 - 0.05 13.9 0.3 27 5.2 0.0 4.0 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Got1 PF04178.12 KXZ42015.1 - 3.4e-23 82.2 3.9 5.2e-23 81.6 3.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family VKG_Carbox PF05090.14 KXZ42015.1 - 1.1 8.1 6.3 1.2 7.9 6.3 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase SNARE PF05739.19 KXZ42016.1 - 4.2e-10 39.5 1.8 8.2e-10 38.5 1.8 1.5 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 KXZ42016.1 - 0.024 14.4 2.0 0.051 13.3 1.9 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 VirB8 PF04335.13 KXZ42016.1 - 0.096 12.5 0.6 0.16 11.8 0.6 1.3 1 0 0 1 1 1 0 VirB8 protein Vps39_2 PF10367.9 KXZ42017.1 - 6.1e-21 74.9 0.3 1e-20 74.2 0.3 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 SEO_C PF14577.6 KXZ42017.1 - 0.26 10.7 0.1 0.45 9.9 0.1 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Retrotran_gag_2 PF14223.6 KXZ42018.1 - 3.6e-22 78.5 0.0 5.2e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KXZ42018.1 - 1e-11 44.4 12.2 1.3e-07 31.4 1.9 2.4 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.17 KXZ42018.1 - 5.4e-05 23.4 0.0 0.00074 19.7 0.0 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_4 PF14392.6 KXZ42018.1 - 6e-05 22.7 7.5 0.025 14.3 1.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KXZ42018.1 - 0.0018 18.1 9.2 0.02 14.7 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle CLIP1_ZNF PF16641.5 KXZ42018.1 - 0.036 13.9 6.7 0.6 10.1 0.4 2.4 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-RING_9 PF13901.6 KXZ42018.1 - 0.078 13.0 3.5 0.12 12.3 3.5 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-C2H2_10 PF16588.5 KXZ42018.1 - 0.32 10.8 13.1 1.1 9.1 3.5 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 KXZ42018.1 - 0.95 9.5 9.6 4.8 7.2 1.3 2.4 1 1 1 2 2 2 0 Zinc knuckle Retrotran_gag_2 PF14223.6 KXZ42019.1 - 6.5e-16 58.2 0.7 2.5e-07 30.5 0.0 2.1 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KXZ42019.1 - 1.9e-05 24.5 5.6 2.8e-05 24.0 5.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXZ42019.1 - 0.36 10.7 5.7 0.53 10.2 5.7 1.2 1 0 0 1 1 1 0 Zinc knuckle COR PF16095.5 KXZ42020.1 - 2.5e-21 76.4 0.0 4.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 KXZ42020.1 - 2.4e-16 60.0 0.0 4.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 KXZ42020.1 - 7.5e-07 29.6 0.0 2.5e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ42020.1 - 8.2e-07 29.2 0.0 3e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ras PF00071.22 KXZ42020.1 - 1.3e-06 28.1 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Ank PF00023.30 KXZ42020.1 - 3e-06 27.4 0.4 0.0012 19.2 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat Arf PF00025.21 KXZ42020.1 - 3.1e-06 26.8 0.0 5.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_3 PF13606.6 KXZ42020.1 - 0.0017 18.7 0.0 0.027 15.0 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXZ42020.1 - 0.013 16.0 0.0 0.13 12.8 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) AAA_25 PF13481.6 KXZ42020.1 - 0.072 12.7 0.2 0.26 10.9 0.2 1.9 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 KXZ42021.1 - 1.9e-19 70.0 0.3 2.1e-19 69.9 0.3 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42021.1 - 4.6e-15 55.8 0.1 3e-10 40.4 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42021.1 - 1.5e-14 53.7 0.0 8.4e-06 26.0 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXZ42021.1 - 7e-13 47.5 0.0 1.4e-05 25.0 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXZ42021.1 - 1.7e-10 41.0 0.1 1.9e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) UBA PF00627.31 KXZ42021.1 - 0.00046 20.0 0.7 0.51 10.3 0.2 2.9 3 0 0 3 3 3 2 UBA/TS-N domain Calponin PF00402.18 KXZ42021.1 - 0.034 13.8 0.3 15 5.4 0.0 3.1 3 0 0 3 3 3 0 Calponin family repeat HEAT_2 PF13646.6 KXZ42021.1 - 0.042 14.2 0.3 0.57 10.6 0.3 2.1 1 1 0 1 1 1 0 HEAT repeats DUF4129 PF13559.6 KXZ42021.1 - 0.12 12.7 4.0 3.4 8.0 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4129) Synaptobrevin PF00957.21 KXZ42022.1 - 4.6e-33 112.9 0.6 6.3e-33 112.4 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXZ42022.1 - 4.2e-24 84.4 0.1 6.5e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain MCU PF04678.13 KXZ42022.1 - 0.089 12.9 0.2 0.11 12.6 0.2 1.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter TMIE PF16038.5 KXZ42022.1 - 0.34 10.8 2.5 0.83 9.5 2.5 1.6 1 0 0 1 1 1 0 TMIE protein PQ-loop PF04193.14 KXZ42023.1 - 2.2e-26 91.4 12.7 4e-14 52.1 2.6 2.6 3 0 0 3 3 3 2 PQ loop repeat SARAF PF06682.12 KXZ42023.1 - 0.2 11.3 3.7 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis MtN3_slv PF03083.16 KXZ42023.1 - 0.49 10.5 0.1 0.49 10.5 0.1 2.4 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DTW PF03942.15 KXZ42024.1 - 1.1e-16 61.1 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 DTW domain TFIIA PF03153.13 KXZ42024.1 - 0.76 9.7 15.1 1.1 9.2 15.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 KXZ42024.1 - 1.5 7.7 6.5 2.2 7.2 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AP2 PF00847.20 KXZ42025.1 - 5e-06 26.6 1.1 7.3e-06 26.1 1.1 1.3 1 0 0 1 1 1 1 AP2 domain LicD PF04991.13 KXZ42026.1 - 0.0018 18.5 0.0 0.09 12.9 0.0 2.1 2 0 0 2 2 2 2 LicD family PaO PF08417.12 KXZ42027.1 - 2.1e-06 27.8 0.7 1.3e-05 25.2 0.7 2.3 1 1 0 1 1 1 1 Pheophorbide a oxygenase SKG6 PF08693.10 KXZ42028.1 - 0.03 13.7 9.1 0.068 12.6 9.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Maf1 PF09174.10 KXZ42029.1 - 3.2e-45 154.4 4.9 3e-44 151.3 4.9 2.1 1 1 0 1 1 1 1 Maf1 regulator VWA_3 PF13768.6 KXZ42031.1 - 7.5e-13 48.7 0.0 2.9e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KXZ42031.1 - 2.7e-05 24.8 0.0 6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXZ42031.1 - 0.027 14.7 0.0 0.059 13.6 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain YuzL PF14115.6 KXZ42031.1 - 0.055 14.0 5.4 4.3 7.9 0.3 2.5 2 0 0 2 2 2 0 YuzL-like protein CBM_25 PF03423.13 KXZ42031.1 - 0.12 12.7 3.4 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Carbohydrate binding domain (family 25) FAM76 PF16046.5 KXZ42032.1 - 0.00043 19.8 10.0 0.00055 19.4 10.0 1.2 1 0 0 1 1 1 1 FAM76 protein AAA_23 PF13476.6 KXZ42032.1 - 0.0029 18.1 3.5 0.0032 18.0 3.5 1.3 1 0 0 1 1 1 1 AAA domain HemX PF04375.14 KXZ42032.1 - 0.0036 16.6 7.0 0.0055 16.0 7.0 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 KXZ42032.1 - 0.02 14.0 10.4 0.027 13.6 10.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MPS2 PF17060.5 KXZ42032.1 - 0.02 14.2 7.7 0.027 13.8 7.7 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Spc7 PF08317.11 KXZ42032.1 - 0.022 13.7 13.0 0.03 13.2 13.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KXZ42032.1 - 0.049 13.2 4.9 0.064 12.8 4.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 KXZ42032.1 - 0.12 11.8 22.0 0.2 11.1 22.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 KXZ42032.1 - 2.6 7.3 6.6 4.5 6.5 6.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SAP PF02037.27 KXZ42033.1 - 1.3e-07 31.2 0.1 2.4e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 SAP domain FAD_binding_4 PF01565.23 KXZ42034.1 - 1.6e-12 47.4 0.1 3.6e-10 39.7 0.0 2.6 2 0 0 2 2 2 2 FAD binding domain FAD_binding_4 PF01565.23 KXZ42035.1 - 1.4e-12 47.5 0.2 3.8e-10 39.7 0.1 2.8 2 0 0 2 2 2 2 FAD binding domain Lipase_3 PF01764.25 KXZ42036.1 - 2e-28 99.0 0.0 2.7e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KXZ42036.1 - 3.9e-05 23.3 0.2 0.021 14.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KXZ42036.1 - 0.00057 19.2 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXZ42036.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.22 KXZ42036.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Cutinase GST_C_2 PF13410.6 KXZ42037.1 - 2.6e-10 40.2 0.3 1.2e-09 38.0 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXZ42037.1 - 4.5e-08 33.3 0.0 1.6e-07 31.6 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ42037.1 - 0.0059 16.8 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 KXZ42037.1 - 0.038 14.6 0.0 0.065 13.8 0.0 1.3 1 0 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 LMWPc PF01451.21 KXZ42038.1 - 0.06 13.7 0.0 0.56 10.6 0.0 2.2 1 1 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase Gpi16 PF04113.14 KXZ42038.1 - 0.16 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component NDUFB10 PF10249.9 KXZ42040.1 - 0.0022 18.5 0.4 0.0031 18.0 0.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HTH_44 PF14641.6 KXZ42040.1 - 0.13 12.7 0.3 0.39 11.2 0.0 2.0 3 0 0 3 3 3 0 Helix-turn-helix DNA-binding domain of SPT6 CytochromB561_N PF09786.9 KXZ42041.1 - 4.5e-32 111.8 0.0 6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Complex1_LYR PF05347.15 KXZ42042.1 - 0.037 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Rer1 PF03248.13 KXZ42044.1 - 7.9e-58 195.0 3.7 9.9e-58 194.6 3.7 1.1 1 0 0 1 1 1 1 Rer1 family DUF2499 PF10693.9 KXZ42045.1 - 1.8e-26 92.2 1.1 2.1e-26 92.0 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3429 PF11911.8 KXZ42045.1 - 0.056 13.7 2.6 0.066 13.5 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) IPK PF03770.16 KXZ42046.1 - 5.4e-38 130.8 0.0 1.1e-37 129.8 0.0 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase DBI_PRT PF02277.17 KXZ42047.1 - 3.2e-79 266.5 30.4 1.4e-39 136.3 13.0 3.0 3 0 0 3 3 3 3 Phosphoribosyltransferase UPF0444 PF15475.6 KXZ42047.1 - 7.1 7.0 11.3 0.1 12.8 1.2 2.9 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 TIM PF00121.18 KXZ42048.1 - 2.6e-85 285.7 0.0 3e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ATP-synt PF00231.19 KXZ42048.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 ATP synthase Phasin_2 PF09361.10 KXZ42049.1 - 1.1 9.5 12.8 0.55 10.5 7.4 2.1 2 0 0 2 2 2 0 Phasin protein EccE PF11203.8 KXZ42049.1 - 9.1 6.7 15.9 1.5 9.2 6.8 2.2 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Roc PF08477.13 KXZ42050.1 - 1.4e-15 57.5 0.0 2.7e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ42050.1 - 2.5e-11 43.8 0.0 4.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_5 PF13857.6 KXZ42050.1 - 3.4e-08 33.6 0.0 1.2e-07 31.9 0.0 1.9 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42050.1 - 3.2e-07 30.8 0.0 1.3e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ42050.1 - 1.2e-06 28.7 0.1 5.6e-05 23.4 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ras PF00071.22 KXZ42050.1 - 1.3e-05 24.9 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ42050.1 - 0.00015 21.3 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_3 PF13606.6 KXZ42050.1 - 0.00036 20.8 0.2 0.005 17.2 0.0 3.1 4 0 0 4 4 2 1 Ankyrin repeat Mg_chelatase PF01078.21 KXZ42050.1 - 0.0024 17.3 0.2 0.0039 16.6 0.2 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ42050.1 - 0.0048 17.3 0.3 0.21 12.0 0.2 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXZ42050.1 - 0.021 15.1 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ank_4 PF13637.6 KXZ42050.1 - 0.022 15.3 0.0 0.098 13.3 0.0 2.1 2 0 0 2 2 1 0 Ankyrin repeats (many copies) AAA_25 PF13481.6 KXZ42050.1 - 0.088 12.4 2.2 0.1 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KXZ42050.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KXZ42050.1 - 0.14 12.6 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KXZ42050.1 - 0.18 12.0 0.3 0.44 10.7 0.3 1.6 1 0 0 1 1 1 0 AAA domain BAG PF02179.16 KXZ42050.1 - 0.2 12.1 0.1 0.5 10.8 0.1 1.6 1 0 0 1 1 1 0 BAG domain IstB_IS21 PF01695.17 KXZ42050.1 - 0.21 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TPT PF03151.16 KXZ42051.1 - 8.1e-09 35.2 5.1 2.3e-07 30.4 2.6 2.0 1 1 1 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KXZ42051.1 - 0.0088 15.3 4.9 0.0088 15.3 4.9 1.8 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.20 KXZ42051.1 - 0.17 12.0 16.6 0.45 10.7 16.8 1.6 1 1 0 1 1 1 0 EamA-like transporter family DUF2070 PF09843.9 KXZ42051.1 - 5.1 5.3 11.4 6.3 5.0 11.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ion_trans PF00520.31 KXZ42052.1 - 0.00061 19.1 10.7 0.0011 18.2 10.7 1.5 1 1 0 1 1 1 1 Ion transport protein Laminin_II PF06009.12 KXZ42053.1 - 0.0064 16.5 2.0 0.0093 16.0 2.0 1.2 1 0 0 1 1 1 1 Laminin Domain II Ion_trans PF00520.31 KXZ42053.1 - 0.0077 15.5 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Ion transport protein Spectrin PF00435.21 KXZ42053.1 - 0.011 16.2 1.8 0.016 15.7 1.8 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF885 PF05960.11 KXZ42053.1 - 0.011 15.4 0.4 0.015 15.0 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) TMF_TATA_bd PF12325.8 KXZ42053.1 - 0.019 15.1 1.7 0.031 14.5 1.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding VlpA_repeat PF04649.12 KXZ42053.1 - 0.57 10.5 2.5 1.3 9.4 2.5 1.6 1 0 0 1 1 1 0 Mycoplasma hyorhinis VlpA repeat ABC_tran_CTD PF16326.5 KXZ42053.1 - 0.71 10.2 3.2 18 5.6 3.2 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Mcm10 PF09332.11 KXZ42054.1 - 3.1e-14 53.2 2.6 4.1e-14 52.8 2.6 1.1 1 0 0 1 1 1 1 Mcm10 replication factor Mut7-C PF01927.16 KXZ42054.1 - 0.0081 16.3 1.9 0.0081 16.3 1.9 2.1 1 1 1 2 2 2 1 Mut7-C RNAse domain DUF3716 PF12511.8 KXZ42054.1 - 0.066 13.3 0.5 0.066 13.3 0.5 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3716) HypA PF01155.19 KXZ42054.1 - 0.2 11.7 5.1 0.5 10.4 5.1 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RanBP PF00641.18 KXZ42054.1 - 0.2 11.0 12.8 0.67 9.3 0.3 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Rubredoxin_2 PF18073.1 KXZ42054.1 - 0.2 11.4 7.2 3.5 7.4 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf_UBZ PF18439.1 KXZ42054.1 - 0.8 9.4 4.8 9.2 6.0 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KXZ42054.1 - 8.7 6.9 7.8 25 5.4 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4379 PF14311.6 KXZ42054.1 - 9.3 6.7 11.6 9.5 6.7 4.1 2.6 1 1 1 2 2 2 0 Probable Zinc-ribbon domain HGTP_anticodon PF03129.20 KXZ42055.1 - 3.5e-08 33.5 0.0 1.1e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 Anticodon binding domain Pkinase PF00069.25 KXZ42056.1 - 2.4e-61 207.4 0.0 3.1e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42056.1 - 1.1e-42 146.2 0.0 1.4e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ42056.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ42056.1 - 0.00021 20.2 0.0 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXZ42056.1 - 0.0083 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Ank_2 PF12796.7 KXZ42059.1 - 8.3e-24 84.0 0.3 1.5e-15 57.5 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42059.1 - 3.8e-19 68.8 0.1 3.8e-07 30.5 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42059.1 - 4.5e-15 55.3 0.1 0.00012 22.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KXZ42059.1 - 9.5e-14 50.2 0.4 0.0009 19.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ42059.1 - 3.1e-13 49.7 1.6 0.00068 19.9 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) COR PF16095.5 KXZ42062.1 - 3e-18 66.3 0.0 4.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 KXZ42062.1 - 3.3e-06 27.3 0.0 5.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank PF00023.30 KXZ42062.1 - 2.1e-05 24.7 0.1 7.8e-05 23.0 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeat Arf PF00025.21 KXZ42062.1 - 9.8e-05 21.9 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_2 PF12796.7 KXZ42062.1 - 0.00028 21.4 0.1 0.0012 19.4 0.1 2.0 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42062.1 - 0.0066 16.9 0.0 0.024 15.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat AAA_25 PF13481.6 KXZ42062.1 - 0.0083 15.7 0.4 0.029 13.9 0.4 1.9 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.6 KXZ42062.1 - 0.013 16.1 0.0 0.055 14.1 0.0 2.1 3 0 0 3 3 1 0 Ankyrin repeats (many copies) Ras PF00071.22 KXZ42062.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Ras family AAA_33 PF13671.6 KXZ42062.1 - 0.035 14.3 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXZ42062.1 - 0.052 13.8 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXZ42062.1 - 0.058 12.8 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ42062.1 - 0.08 13.3 0.3 0.45 10.9 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KXZ42062.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 KXZ42062.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein BAG PF02179.16 KXZ42062.1 - 0.11 12.9 0.1 0.34 11.4 0.1 1.8 1 0 0 1 1 1 0 BAG domain RsgA_GTPase PF03193.16 KXZ42062.1 - 0.14 12.0 0.1 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KXZ42062.1 - 0.16 12.5 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KXZ42062.1 - 0.26 11.0 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RRM_7 PF16367.5 KXZ42064.1 - 0.034 14.2 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif XhoI PF04555.13 KXZ42064.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease XhoI peroxidase PF00141.23 KXZ42065.1 - 6.3e-33 114.4 0.0 4.8e-32 111.5 0.0 1.9 1 1 0 1 1 1 1 Peroxidase PSI_PsaH PF03244.14 KXZ42065.1 - 0.32 10.5 1.8 7.3 6.1 0.1 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VI Chloroa_b-bind PF00504.21 KXZ42066.1 - 1.9e-51 174.8 0.0 2.5e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 KXZ42067.1 - 8.3e-29 101.2 0.0 9.8e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NCOA_u2 PF16665.5 KXZ42069.1 - 0.089 13.1 0.3 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein NifQ PF04891.12 KXZ42069.1 - 0.36 11.2 4.0 0.5 10.7 4.0 1.4 1 0 0 1 1 1 0 NifQ RFamide_26RFa PF11109.8 KXZ42069.1 - 0.97 10.0 8.5 2.2 8.8 8.3 1.8 1 1 1 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 ADP_ribosyl_GH PF03747.14 KXZ42069.1 - 1.8 8.2 5.9 2.7 7.7 5.8 1.3 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase DDHD PF02862.17 KXZ42069.1 - 2.2 8.4 4.6 2.6 8.1 4.6 1.2 1 0 0 1 1 1 0 DDHD domain Transposase_24 PF03004.14 KXZ42069.1 - 2.2 8.4 8.6 1.3 9.1 6.0 1.7 1 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF4239 PF14023.6 KXZ42069.1 - 3.4 7.3 7.2 7.1 6.3 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) PIN_9 PF18477.1 KXZ42069.1 - 4.1 7.7 8.1 11 6.4 4.9 2.2 1 1 0 2 2 2 0 PIN like domain Presenilin PF01080.17 KXZ42069.1 - 7.3 5.2 5.2 8 5.1 5.2 1.1 1 0 0 1 1 1 0 Presenilin VIT1 PF01988.19 KXZ42069.1 - 8.5 6.2 6.2 13 5.6 6.2 1.3 1 0 0 1 1 1 0 VIT family OSCP PF00213.18 KXZ42070.1 - 6.8e-48 163.0 6.5 8e-48 162.8 6.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Cytokin_check_N PF10407.9 KXZ42070.1 - 0.12 12.4 0.3 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus DUF455 PF04305.14 KXZ42072.1 - 5.4e-81 271.8 0.3 1.2e-70 237.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF455) Ank_2 PF12796.7 KXZ42073.1 - 1.1e-08 35.5 0.1 0.066 13.8 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) HTH_39 PF14090.6 KXZ42073.1 - 0.018 14.8 0.0 0.14 12.0 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Fringe PF02434.16 KXZ42073.1 - 0.065 12.7 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Fringe-like F420_oxidored PF03807.17 KXZ42075.1 - 1.6e-11 44.6 0.3 3.3e-11 43.6 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KXZ42075.1 - 3.4e-11 43.1 1.3 6.8e-11 42.1 1.3 1.5 1 0 0 1 1 1 1 Rossmann-like domain NAD_binding_2 PF03446.15 KXZ42075.1 - 6.1e-06 26.5 0.3 1.1e-05 25.6 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KXZ42075.1 - 0.00048 19.7 0.2 0.00071 19.2 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain CoA_binding PF02629.19 KXZ42075.1 - 0.00067 20.3 2.3 0.0024 18.5 0.9 2.1 2 0 0 2 2 2 1 CoA binding domain NAD_Gly3P_dh_N PF01210.23 KXZ42075.1 - 0.0017 18.4 0.8 0.033 14.1 0.8 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KXZ42075.1 - 0.0024 17.5 0.6 0.047 13.3 0.3 2.6 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 KXZ42075.1 - 0.0088 16.0 1.6 0.049 13.5 0.5 2.4 2 1 0 3 3 3 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KXZ42075.1 - 0.014 14.7 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DNA_pol_B PF00136.21 KXZ42076.1 - 8.4e-12 44.5 0.0 3e-06 26.2 0.0 2.0 2 0 0 2 2 2 2 DNA polymerase family B zf-C4pol PF14260.6 KXZ42076.1 - 0.00033 21.0 0.0 0.00055 20.3 0.0 1.3 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B PF00136.21 KXZ42077.1 - 4.5e-49 167.4 0.0 5.4e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B RMP PF14996.6 KXZ42078.1 - 5.6e-43 146.8 1.6 7.4e-43 146.4 1.6 1.2 1 0 0 1 1 1 1 Retinal Maintenance Ras PF00071.22 KXZ42079.1 - 3e-18 66.0 0.2 4e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ42079.1 - 1.1e-09 38.5 0.2 1.8e-09 37.9 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 KXZ42079.1 - 0.0073 16.3 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 KXZ42079.1 - 0.017 14.6 1.9 0.091 12.3 0.3 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 KXZ42079.1 - 0.022 14.2 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family NOG1 PF06858.14 KXZ42079.1 - 0.069 12.9 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) YwhD PF08741.10 KXZ42079.1 - 0.1 12.3 0.5 0.24 11.1 0.2 1.7 2 0 0 2 2 2 0 YwhD family M3 PF09213.10 KXZ42079.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 M3 UPF0020 PF01170.18 KXZ42082.1 - 7e-23 81.3 0.0 3e-22 79.3 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ribosomal_L11_N PF03946.14 KXZ42083.1 - 2.4e-26 91.3 0.1 4.2e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXZ42083.1 - 1.1e-21 77.1 0.0 1.7e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain FAE1_CUT1_RppA PF08392.12 KXZ42084.1 - 4.8e-129 429.8 0.0 6.1e-129 429.4 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 KXZ42084.1 - 9.2e-12 45.2 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 KXZ42084.1 - 2.7e-09 37.1 0.0 1.7e-08 34.5 0.0 2.2 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KXZ42084.1 - 0.0022 17.8 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GDP_Man_Dehyd PF16363.5 KXZ42086.1 - 5.7e-65 219.9 0.0 6.5e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXZ42086.1 - 3.3e-52 177.3 0.1 4.1e-52 177.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXZ42086.1 - 2.2e-16 59.9 0.0 3.9e-15 55.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXZ42086.1 - 1.2e-15 57.3 0.0 1.7e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXZ42086.1 - 1.5e-14 53.8 0.0 2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXZ42086.1 - 1e-12 47.8 0.1 3.7e-12 45.9 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein Ank_2 PF12796.7 KXZ42090.1 - 5e-09 36.6 0.5 0.0067 17.0 0.2 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42090.1 - 1.4e-05 25.5 5.8 4.9 7.8 0.1 6.2 3 3 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42090.1 - 0.00016 21.8 1.1 30 5.6 0.0 6.2 5 1 1 6 6 6 2 Ankyrin repeat YchF-GTPase_C PF06071.13 KXZ42091.1 - 2.1e-38 130.4 0.5 4.6e-38 129.3 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXZ42091.1 - 1.6e-21 76.5 0.0 2.7e-21 75.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ42091.1 - 9.2e-08 31.8 0.0 2.1e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KXZ42091.1 - 0.025 14.8 0.0 0.22 11.7 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Tropomyosin_1 PF12718.7 KXZ42094.1 - 0.0006 20.0 0.6 0.00076 19.7 0.6 1.1 1 0 0 1 1 1 1 Tropomyosin like FtsL PF04999.13 KXZ42094.1 - 0.058 13.4 0.3 0.09 12.8 0.3 1.4 1 0 0 1 1 1 0 Cell division protein FtsL YabA PF06156.13 KXZ42094.1 - 0.077 13.6 1.1 0.13 13.0 1.1 1.5 1 1 0 1 1 1 0 Initiation control protein YabA RT_RNaseH_2 PF17919.1 KXZ42095.1 - 3.3e-33 113.7 0.0 6.7e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ42095.1 - 1.3e-31 109.0 0.1 2.5e-31 108.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KXZ42095.1 - 1.1e-13 51.0 0.5 1.1e-13 51.0 0.5 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KXZ42095.1 - 0.074 13.3 0.5 0.17 12.1 0.5 1.7 1 0 0 1 1 1 0 H2C2 zinc finger ABC_tran PF00005.27 KXZ42096.1 - 1.6e-07 32.0 0.0 2.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter COR PF16095.5 KXZ42098.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain ABC_tran PF00005.27 KXZ42099.1 - 7.1e-10 39.5 0.0 1.5e-09 38.5 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KXZ42099.1 - 0.022 14.6 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF659 PF04937.15 KXZ42100.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) FMO-like PF00743.19 KXZ42101.1 - 1.4e-05 23.7 0.0 1.4e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXZ42101.1 - 0.004 16.5 0.0 0.0043 16.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ42101.1 - 0.0041 16.4 0.0 0.0047 16.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ42101.1 - 0.0042 16.3 0.0 0.0046 16.2 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXZ42101.1 - 0.021 15.3 0.0 0.029 14.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXZ42101.1 - 0.087 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PEP_mutase PF13714.6 KXZ42102.1 - 1.3e-23 83.8 0.0 1.9e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXZ42102.1 - 0.00012 20.7 0.0 0.00017 20.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Serglycin PF04360.12 KXZ42102.1 - 0.068 13.1 1.0 0.11 12.5 1.0 1.2 1 0 0 1 1 1 0 Serglycin MSP1_C PF07462.11 KXZ42102.1 - 3.2 6.3 3.9 4.6 5.8 3.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus UPF0004 PF00919.20 KXZ42103.1 - 4.3e-17 62.0 0.0 7.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KXZ42103.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily Radical_SAM PF04055.21 KXZ42104.1 - 0.015 15.7 0.0 0.017 15.5 0.0 1.0 1 0 0 1 1 1 0 Radical SAM superfamily Roc PF08477.13 KXZ42105.1 - 6.1e-23 81.3 0.0 1.1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ42105.1 - 2.6e-18 66.6 0.0 4.1e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 KXZ42105.1 - 6.6e-13 48.6 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ42105.1 - 2.2e-05 24.0 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXZ42105.1 - 0.0004 19.9 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXZ42105.1 - 0.006 16.1 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Spore_IV_A PF09547.10 KXZ42105.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) MMR_HSR1 PF01926.23 KXZ42105.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ank_4 PF13637.6 KXZ42105.1 - 0.034 14.7 0.0 0.15 12.7 0.0 2.1 2 0 0 2 2 1 0 Ankyrin repeats (many copies) PduV-EutP PF10662.9 KXZ42105.1 - 0.039 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KXZ42105.1 - 0.041 13.4 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 KXZ42105.1 - 0.043 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ank_2 PF12796.7 KXZ42105.1 - 0.045 14.3 0.0 0.53 10.9 0.0 2.6 3 0 0 3 3 2 0 Ankyrin repeats (3 copies) AAA PF00004.29 KXZ42105.1 - 0.085 13.3 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ42105.1 - 0.11 12.8 0.0 0.6 10.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 KXZ42105.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXZ42105.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pribosyltran PF00156.27 KXZ42106.1 - 1.5e-08 34.3 0.0 1.7e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain COR PF16095.5 KXZ42107.1 - 3.6e-17 62.8 0.0 4.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain COR PF16095.5 KXZ42108.1 - 1.7e-17 63.9 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain CMS1 PF14617.6 KXZ42108.1 - 0.12 11.7 0.0 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF1805 PF08827.11 KXZ42108.1 - 0.14 12.5 1.3 0.58 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) COR PF16095.5 KXZ42109.1 - 6e-19 68.6 0.0 9.1e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain BAG PF02179.16 KXZ42109.1 - 0.1 13.0 0.3 0.46 11.0 0.1 2.1 2 0 0 2 2 2 0 BAG domain Pkinase_Tyr PF07714.17 KXZ42110.1 - 4.4e-50 170.4 0.0 8.6e-42 143.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ42110.1 - 5.6e-42 143.9 0.0 1.2e-41 142.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ42110.1 - 2.2e-05 23.5 0.1 3.6e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ42110.1 - 0.00094 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CHASE PF03924.13 KXZ42110.1 - 0.014 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 CHASE domain Sds3 PF08598.11 KXZ42110.1 - 0.046 13.7 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Sds3-like Polysacc_synt PF01943.17 KXZ42110.1 - 0.074 12.4 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Bestrophin PF01062.21 KXZ42110.1 - 0.17 11.2 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RGP PF03214.13 KXZ42111.1 - 2.9e-174 579.1 0.0 3.3e-174 578.9 0.0 1.0 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide Glyco_tranf_2_2 PF10111.9 KXZ42111.1 - 0.056 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 NTP_transf_2 PF01909.23 KXZ42112.1 - 1.5e-06 28.4 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KXZ42112.1 - 2.8e-05 24.2 0.0 5.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KXZ42112.1 - 0.0045 17.0 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase zf-C3HC PF07967.13 KXZ42113.1 - 1.2e-26 93.3 0.4 1.2e-26 93.3 0.4 2.3 3 0 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.10 KXZ42113.1 - 2.4e-09 37.2 3.3 0.041 14.0 0.0 4.3 4 0 0 4 4 4 3 Rsm1-like ATX_III PF08098.11 KXZ42113.1 - 0.044 13.8 0.7 0.044 13.8 0.7 2.4 2 0 0 2 2 2 0 Anemonia sulcata toxin III family Glyco_hydro_85 PF03644.13 KXZ42114.1 - 2.9e-59 201.0 0.0 4e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF4743 PF15916.5 KXZ42115.1 - 3.9e-12 46.2 0.0 5.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KXZ42115.1 - 1.3e-08 35.0 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain BioT2 PF15368.6 KXZ42116.1 - 0.32 10.9 0.8 7 6.6 0.0 2.7 3 0 0 3 3 3 0 Spermatogenesis family BioT2 ABC1 PF03109.16 KXZ42117.1 - 8.4e-36 122.7 0.0 1.4e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KXZ42117.1 - 2.5e-05 23.8 0.0 0.016 14.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ42117.1 - 0.0034 17.3 3.6 0.0053 16.7 0.6 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 KXZ42117.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) ABA_WDS PF02496.16 KXZ42118.1 - 0.15 12.6 1.1 4.7 7.8 0.8 2.2 2 0 0 2 2 2 0 ABA/WDS induced protein ABA_WDS PF02496.16 KXZ42119.1 - 0.12 12.9 1.1 4.2 7.9 0.8 2.2 2 0 0 2 2 2 0 ABA/WDS induced protein Tropomyosin PF00261.20 KXZ42120.1 - 0.0042 16.5 13.5 0.0042 16.5 13.5 2.1 1 1 1 2 2 2 1 Tropomyosin Tropomyosin_1 PF12718.7 KXZ42120.1 - 0.012 15.7 12.8 0.012 15.7 12.8 2.1 2 0 0 2 2 2 0 Tropomyosin like Laminin_II PF06009.12 KXZ42120.1 - 0.23 11.5 8.6 0.67 10.0 4.8 2.2 2 0 0 2 2 2 0 Laminin Domain II DHR10 PF18595.1 KXZ42120.1 - 0.33 11.0 38.4 1.2 9.2 5.8 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain EzrA PF06160.12 KXZ42120.1 - 0.34 9.0 6.7 0.19 9.9 2.7 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 KXZ42120.1 - 0.58 9.0 22.6 1.4 7.8 12.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein PEARLI-4 PF05278.12 KXZ42120.1 - 2.2 7.8 10.2 0.43 10.1 2.6 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) SNARE PF05739.19 KXZ42121.1 - 3.8e-07 30.0 0.5 3.8e-07 30.0 0.5 2.3 2 0 0 2 2 2 1 SNARE domain Phage_HK97_TLTM PF06120.11 KXZ42121.1 - 0.01 15.1 1.6 0.01 15.1 1.6 2.1 2 0 0 2 2 2 0 Tail length tape measure protein DUF16 PF01519.16 KXZ42121.1 - 0.023 15.1 3.1 0.023 15.1 3.1 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 Jnk-SapK_ap_N PF09744.9 KXZ42121.1 - 0.034 14.4 12.7 0.46 10.7 4.2 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TMPIT PF07851.13 KXZ42121.1 - 0.059 12.6 7.3 0.22 10.7 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein AIP3 PF03915.13 KXZ42121.1 - 0.063 12.4 9.4 0.1 11.7 1.5 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 DUF3450 PF11932.8 KXZ42121.1 - 0.32 10.2 12.6 0.55 9.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) ING PF12998.7 KXZ42121.1 - 0.51 11.0 10.1 1.2 9.8 1.3 3.5 1 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding SMBP PF16785.5 KXZ42121.1 - 0.6 10.3 7.5 0.42 10.8 2.6 2.2 2 0 0 2 2 2 0 Small metal-binding protein eIF3_N PF09440.10 KXZ42121.1 - 0.65 10.4 12.4 1.8 9.0 2.4 2.7 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain UPF0242 PF06785.11 KXZ42121.1 - 0.67 10.0 13.2 0.81 9.8 2.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 KXZ42121.1 - 0.78 10.3 13.2 3.2 8.4 3.5 3.4 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Spore_III_AB PF09548.10 KXZ42121.1 - 0.97 9.5 7.9 0.24 11.5 1.8 2.4 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Phage_Gp19 PF09355.10 KXZ42121.1 - 1.2 9.6 9.9 1.2 9.6 0.7 3.0 2 2 1 3 3 3 0 Phage protein Gp19/Gp15/Gp42 Peptidase_M32 PF02074.15 KXZ42121.1 - 1.9 7.2 8.0 3.6 6.3 7.9 1.4 1 1 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF1664 PF07889.12 KXZ42121.1 - 2.8 8.0 12.6 0.68 10.0 3.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KXZ42121.1 - 2.9 8.1 9.0 5.3 7.2 1.7 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1690 PF07956.11 KXZ42121.1 - 3.6 8.0 12.9 1.8 9.0 3.7 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) NPV_P10 PF05531.12 KXZ42121.1 - 4 8.0 10.4 0.62 10.6 2.4 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Use1 PF09753.9 KXZ42121.1 - 4.7 6.9 12.0 19 4.9 12.0 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 ERp29 PF07749.12 KXZ42122.1 - 7.5e-21 74.8 0.6 1.3e-20 74.1 0.6 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain ERp29_N PF07912.13 KXZ42122.1 - 1.2e-19 70.8 0.2 1.8e-19 70.2 0.2 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain CI-B14_5a PF07347.12 KXZ42122.1 - 0.076 12.9 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Pkinase_Tyr PF07714.17 KXZ42123.1 - 1.2e-32 113.3 0.0 1.5e-29 103.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ42123.1 - 3.2e-29 102.1 0.0 1.3e-26 93.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ42123.1 - 0.024 14.6 0.2 0.024 14.6 0.2 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ42123.1 - 0.043 13.2 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ42123.1 - 0.097 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family UPF0121 PF03661.13 KXZ42124.1 - 6.7e-14 51.9 2.5 8e-14 51.6 2.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) AAA_33 PF13671.6 KXZ42125.1 - 0.00012 22.2 0.4 0.19 11.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain zf-dskA_traR PF01258.17 KXZ42125.1 - 4.7 7.2 12.3 25 4.9 0.4 3.7 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Myb_DNA-binding PF00249.31 KXZ42126.1 - 1.2e-27 95.8 5.8 1.6e-14 53.8 0.6 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ42126.1 - 9e-22 77.1 0.2 5e-14 52.3 0.0 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 KXZ42126.1 - 0.00089 19.3 0.6 0.22 11.6 0.0 3.0 2 1 0 3 3 3 1 SLIDE Rap1_C PF11626.8 KXZ42126.1 - 0.0075 16.3 0.1 0.083 13.0 0.0 2.8 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 KXZ42126.1 - 0.14 12.0 1.0 0.39 10.6 0.0 2.1 3 0 0 3 3 3 0 Myb DNA-binding like Fer4_13 PF13370.6 KXZ42126.1 - 5.5 7.6 7.0 0.65 10.6 1.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Transketolase_C PF02780.20 KXZ42127.1 - 4.4e-46 155.8 0.1 8.6e-46 154.9 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KXZ42127.1 - 2e-44 151.4 0.0 2.8e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 KXZ42127.1 - 0.015 15.6 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Glutaredoxin PF00462.24 KXZ42127.1 - 0.039 14.2 0.0 0.21 11.8 0.0 2.2 1 1 1 2 2 2 0 Glutaredoxin HisKA PF00512.25 KXZ42128.1 - 1.1e-11 44.6 0.4 3.8e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Acyl_transf_3 PF01757.22 KXZ42128.1 - 0.14 11.2 4.6 0.23 10.5 4.6 1.3 1 0 0 1 1 1 0 Acyltransferase family TctB PF07331.11 KXZ42128.1 - 0.86 9.9 8.3 0.072 13.4 3.0 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family E1-E2_ATPase PF00122.20 KXZ42129.1 - 2e-46 157.8 0.4 3.3e-46 157.1 0.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXZ42129.1 - 1.5e-32 113.6 14.9 3.8e-32 112.3 10.9 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXZ42129.1 - 5.3e-12 46.0 2.1 1.1e-09 38.6 0.4 3.3 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KXZ42129.1 - 4.7e-05 23.3 0.2 8.4e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXZ42129.1 - 0.14 12.3 0.0 0.76 9.9 0.0 2.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ42129.1 - 0.37 11.2 1.8 0.67 10.3 0.1 2.4 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase MCD PF05292.11 KXZ42130.1 - 1.1e-53 182.4 0.0 4.2e-39 134.7 0.0 2.5 2 1 0 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 KXZ42130.1 - 4.9e-12 45.8 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain DUF21 PF01595.20 KXZ42131.1 - 1.5e-17 63.9 0.0 2.7e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXZ42131.1 - 2.3e-06 27.9 1.9 0.023 15.1 0.3 2.8 2 0 0 2 2 2 2 CBS domain DUF3446 PF11928.8 KXZ42131.1 - 0.0085 16.4 1.5 0.0085 16.4 1.5 3.9 3 1 0 3 3 3 2 Early growth response N-terminal domain SR-25 PF10500.9 KXZ42131.1 - 0.25 10.9 35.8 0.33 10.5 5.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 KXZ42131.1 - 1 7.8 3.4 7.3 4.9 2.1 2.1 2 0 0 2 2 2 0 Peptidase family S64 Apt1 PF10351.9 KXZ42131.1 - 6.1 5.6 13.4 2.2 7.1 4.9 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ribosomal_L19e PF01280.20 KXZ42133.1 - 1e-63 213.7 10.3 1e-63 213.7 10.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e RRM_1 PF00076.22 KXZ42134.1 - 6.1e-11 42.0 0.0 9.7e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KXZ42134.1 - 3.2e-09 37.5 0.2 5.7e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KXZ42134.1 - 1.1e-05 25.2 4.3 3.1e-05 23.9 4.3 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXZ42134.1 - 0.00042 20.1 2.5 0.00042 20.1 2.5 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KXZ42134.1 - 0.0078 16.4 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 KXZ42134.1 - 0.027 14.3 3.0 0.066 13.0 3.0 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger RRM_3 PF08777.11 KXZ42134.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif zf-CCCH_2 PF14608.6 KXZ42134.1 - 0.074 13.6 3.1 0.21 12.1 3.1 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Thiolase_N PF00108.23 KXZ42135.1 - 5.2e-68 229.2 0.0 3.8e-56 190.3 0.0 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXZ42135.1 - 9.7e-40 135.0 0.1 1.9e-38 130.9 0.1 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXZ42135.1 - 2.8e-08 33.7 4.5 8.4e-06 25.5 3.3 2.6 1 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXZ42135.1 - 0.057 13.3 0.2 0.057 13.3 0.2 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Nop14 PF04147.12 KXZ42136.1 - 5.5 5.1 10.9 8.1 4.5 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family AAA PF00004.29 KXZ42138.1 - 4.2e-12 46.6 0.0 6.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRCR PF00530.18 KXZ42139.1 - 1.9e-26 92.5 0.1 1.1e-08 35.4 0.0 3.6 3 1 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ42139.1 - 0.0027 18.2 0.8 0.58 10.7 0.4 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KXZ42140.1 - 7.8e-13 48.8 0.1 1.1e-12 48.3 0.1 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KXZ42141.1 - 4e-17 62.6 13.2 1.6e-08 35.0 0.2 4.1 4 0 0 4 4 4 2 Scavenger receptor cysteine-rich domain Ntox44 PF15607.6 KXZ42141.1 - 0.0024 18.1 0.5 3.3 8.1 0.1 2.4 1 1 1 2 2 2 2 Bacterial toxin 44 NADH-G_4Fe-4S_3 PF10588.9 KXZ42141.1 - 4.4 6.9 8.0 0.77 9.3 2.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region LRR_4 PF12799.7 KXZ42144.1 - 5.3e-11 42.6 7.0 0.0053 17.1 0.1 6.2 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ42144.1 - 8.6e-06 25.4 14.2 0.017 14.8 0.1 5.6 7 1 0 7 7 7 3 Leucine rich repeat LRR_6 PF13516.6 KXZ42144.1 - 0.0016 18.3 0.2 7.8 6.8 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 KXZ42144.1 - 0.51 11.1 11.7 42 5.2 0.1 6.6 9 0 0 9 9 9 0 Leucine Rich Repeat Pan3_PK PF18101.1 KXZ42145.1 - 8.7e-42 142.4 0.0 1.3e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain PAN_4 PF14295.6 KXZ42146.1 - 2.1e-07 30.7 6.4 0.008 16.1 0.1 2.7 2 1 0 2 2 2 2 PAN domain PAN_1 PF00024.26 KXZ42146.1 - 0.00087 19.2 5.4 0.09 12.8 1.5 2.2 1 1 1 2 2 2 2 PAN domain PAN_4 PF14295.6 KXZ42147.1 - 0.084 12.8 1.9 3.8 7.5 0.6 2.6 2 0 0 2 2 2 0 PAN domain zf-CCHC PF00098.23 KXZ42148.1 - 0.00051 20.0 2.5 0.00085 19.3 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KXZ42148.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 KXZ42148.1 - 0.17 11.6 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle UCH PF00443.29 KXZ42153.1 - 2.8e-38 131.9 0.0 2e-32 112.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ42153.1 - 0.0024 17.5 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase LSM PF01423.22 KXZ42154.1 - 8.2e-19 67.1 0.0 1.1e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXZ42154.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Patatin PF01734.22 KXZ42156.1 - 5.1e-10 39.9 5.2 3.5e-08 33.9 2.5 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase F-box PF00646.33 KXZ42157.1 - 0.0023 17.8 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXZ42157.1 - 0.0043 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Polyketide_cyc2 PF10604.9 KXZ42158.1 - 0.0021 18.4 0.9 0.0039 17.5 0.9 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ank_4 PF13637.6 KXZ42159.1 - 4.1e-09 36.8 0.3 0.058 14.0 0.3 4.9 3 3 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42159.1 - 4.6e-08 32.7 0.1 13 6.7 0.0 6.2 5 1 1 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 KXZ42159.1 - 7.4e-08 32.9 0.0 0.00025 21.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Methyltransf_11 PF08241.12 KXZ42160.1 - 0.021 15.4 0.0 1.1 9.9 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ42160.1 - 0.033 14.9 0.1 13 6.6 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Pkinase PF00069.25 KXZ42161.1 - 2.3e-43 148.4 0.0 1.3e-39 136.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42161.1 - 7.6e-40 136.8 0.0 4.7e-36 124.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2227 PF09988.9 KXZ42161.1 - 0.22 11.4 0.8 0.94 9.3 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) Fapy_DNA_glyco PF01149.24 KXZ42162.1 - 1.3e-33 116.1 0.0 5.9e-33 113.9 0.0 2.1 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KXZ42162.1 - 3e-14 52.8 0.0 8.1e-14 51.4 0.0 1.7 1 1 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain PseudoU_synth_2 PF00849.22 KXZ42163.1 - 1.9e-22 80.1 0.0 3.4e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 RNA pseudouridylate synthase AfsA PF03756.13 KXZ42164.1 - 0.072 13.1 0.4 2.4 8.2 0.2 2.0 1 1 1 2 2 2 0 A-factor biosynthesis hotdog domain RRM_1 PF00076.22 KXZ42166.1 - 1.9e-11 43.6 0.0 3.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3906 PF13046.6 KXZ42166.1 - 0.0016 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3906) ABC1 PF03109.16 KXZ42167.1 - 2.1e-33 115.0 0.0 3.2e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KXZ42167.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Ank_2 PF12796.7 KXZ42168.1 - 0.00021 21.8 0.0 2.8 8.6 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42168.1 - 0.00046 20.4 0.1 38 5.3 0.0 6.1 7 0 0 7 7 7 0 Ankyrin repeat F-box PF00646.33 KXZ42168.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain Ank_4 PF13637.6 KXZ42168.1 - 0.023 15.3 0.3 1e+02 3.6 0.0 4.9 4 1 2 6 6 6 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ42168.1 - 0.047 14.0 0.1 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Pyr_redox_2 PF07992.14 KXZ42169.1 - 3.3e-14 52.8 0.0 5.9e-06 25.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ42169.1 - 2.3e-06 28.1 0.0 4.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NADHdh PF00146.21 KXZ42170.1 - 0.037 13.3 0.1 0.057 12.7 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase Phage_integrase PF00589.22 KXZ42170.1 - 0.048 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family Mito_carr PF00153.27 KXZ42171.1 - 1.6e-33 114.5 16.5 2.5e-13 49.8 1.5 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2723 PF11028.8 KXZ42171.1 - 1.1 9.2 8.1 0.37 10.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) ERM PF00769.19 KXZ42173.1 - 0.025 14.4 51.1 0.031 14.1 51.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Nop14 PF04147.12 KXZ42173.1 - 0.14 10.3 29.5 0.17 10.1 29.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 KXZ42173.1 - 0.17 12.0 27.0 0.19 11.8 27.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Spc7 PF08317.11 KXZ42173.1 - 0.26 10.1 32.2 0.45 9.3 32.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein WTX PF09422.10 KXZ42173.1 - 0.53 9.3 19.3 0.62 9.1 19.3 1.0 1 0 0 1 1 1 0 WTX protein DAP_B PF07930.12 KXZ42173.1 - 0.78 9.7 8.7 1.2 9.0 8.4 1.4 1 1 0 1 1 1 0 D-aminopeptidase, domain B AAA_13 PF13166.6 KXZ42173.1 - 0.94 8.0 25.3 1.1 7.8 25.3 1.1 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 KXZ42173.1 - 1.1 8.7 25.8 1.4 8.3 25.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 RR_TM4-6 PF06459.12 KXZ42173.1 - 1.3 8.8 30.5 1.8 8.4 30.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 KXZ42173.1 - 1.4 7.8 19.9 1.6 7.7 19.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 KXZ42173.1 - 1.4 6.9 18.0 1.6 6.8 18.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FapA PF03961.13 KXZ42173.1 - 1.5 7.3 22.6 1.8 7.1 22.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_11 PF13086.6 KXZ42173.1 - 1.8 8.3 21.9 2.6 7.8 21.9 1.3 1 0 0 1 1 1 0 AAA domain RP-C_C PF11800.8 KXZ42173.1 - 1.9 8.6 16.1 2.6 8.1 16.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Sec62 PF03839.16 KXZ42173.1 - 1.9 7.9 24.3 2.5 7.5 24.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4776 PF16003.5 KXZ42173.1 - 2.2 7.2 23.6 2.4 7.1 23.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) ALMT PF11744.8 KXZ42173.1 - 2.3 6.9 18.8 2.6 6.8 18.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4045 PF13254.6 KXZ42173.1 - 2.6 7.6 22.1 3.1 7.4 22.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3807 PF12720.7 KXZ42173.1 - 2.8 8.2 27.2 3.8 7.7 27.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) MAJIN PF15077.6 KXZ42173.1 - 2.8 7.7 16.5 3.4 7.4 16.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF778 PF05608.12 KXZ42173.1 - 2.9 8.2 5.1 3.4 8.0 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF913 PF06025.12 KXZ42173.1 - 3.3 6.6 13.1 4.4 6.2 13.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 KXZ42173.1 - 3.4 6.3 21.3 3.7 6.2 21.3 1.1 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 KXZ42173.1 - 3.5 6.0 43.9 4.1 5.8 43.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.13 KXZ42173.1 - 3.7 6.2 19.2 4.2 6.1 19.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4778 PF16008.5 KXZ42173.1 - 3.8 7.5 14.8 4.4 7.3 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) CDC45 PF02724.14 KXZ42173.1 - 4.4 5.5 27.0 5.1 5.3 27.0 1.0 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.17 KXZ42173.1 - 4.5 6.2 11.2 5.6 5.9 11.2 1.3 1 0 0 1 1 1 0 CLN3 protein MCM_bind PF09739.9 KXZ42173.1 - 4.6 5.6 18.0 5.2 5.4 18.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Dsh_C PF12316.8 KXZ42173.1 - 6.2 7.2 6.7 7.5 6.9 6.7 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TP53IP5 PF15331.6 KXZ42173.1 - 6.2 6.9 23.7 7.7 6.6 23.7 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 V_ATPase_I PF01496.19 KXZ42173.1 - 6.5 4.5 18.5 7.5 4.3 18.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KXZ42173.1 - 6.7 6.2 17.8 7.5 6.0 17.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Raftlin PF15250.6 KXZ42173.1 - 6.9 5.3 17.1 7 5.3 17.1 1.0 1 0 0 1 1 1 0 Raftlin Mitofilin PF09731.9 KXZ42173.1 - 7 5.4 34.8 8.4 5.1 34.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CSG2 PF16965.5 KXZ42173.1 - 9.1 5.1 7.3 11 4.8 7.3 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator SAPS PF04499.15 KXZ42173.1 - 9.3 4.9 18.2 9.6 4.9 18.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein XRN_M PF17846.1 KXZ42173.1 - 9.6 5.0 25.3 12 4.8 25.3 1.0 1 0 0 1 1 1 0 Xrn1 helical domain zf-MYND PF01753.18 KXZ42174.1 - 3.5e-07 30.2 4.6 6.2e-07 29.4 4.6 1.3 1 0 0 1 1 1 1 MYND finger DUF531 PF04407.12 KXZ42174.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF531) Catalase PF00199.19 KXZ42175.1 - 9.2e-175 581.3 0.0 1.1e-174 581.1 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXZ42175.1 - 8.9e-15 54.7 0.0 3.3e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Aminotran_3 PF00202.21 KXZ42177.1 - 2.5e-86 289.9 0.0 1.5e-85 287.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-III DUF3551 PF12071.8 KXZ42177.1 - 0.005 16.9 2.0 0.02 14.9 2.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3551) Nucleotid_trans PF03407.16 KXZ42178.1 - 6.1e-30 104.8 0.0 9.6e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase HNH PF01844.23 KXZ42179.1 - 7.1e-15 54.9 0.2 1e-14 54.4 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 KXZ42179.1 - 7.4e-15 54.5 0.0 1.2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 KXZ42179.1 - 9e-09 35.1 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease EF-hand_1 PF00036.32 KXZ42180.1 - 0.0017 17.8 0.2 0.0036 16.7 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ42180.1 - 0.002 18.6 0.0 0.004 17.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ42180.1 - 0.009 15.5 0.5 0.019 14.4 0.5 1.6 1 0 0 1 1 1 1 EF hand VOMI PF03762.17 KXZ42180.1 - 0.012 15.7 0.4 0.093 12.8 0.4 2.1 1 1 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) EF-hand_8 PF13833.6 KXZ42180.1 - 0.022 14.6 0.1 0.056 13.3 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KXZ42180.1 - 0.05 13.6 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain PBP_N PF17093.5 KXZ42180.1 - 0.38 11.0 3.1 1.8 8.8 0.4 2.3 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus PAN_4 PF14295.6 KXZ42181.1 - 2.2e-07 30.6 9.9 0.015 15.2 0.1 4.0 3 1 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KXZ42181.1 - 1.7e-06 27.9 1.0 0.087 12.8 0.2 3.0 2 1 1 3 3 3 2 PAN domain Rubredoxin PF00301.20 KXZ42181.1 - 0.029 14.4 0.0 9.2 6.4 0.0 3.0 2 0 0 2 2 2 0 Rubredoxin Phage_holin_3_1 PF05106.12 KXZ42181.1 - 0.065 13.7 1.0 5.8 7.4 0.3 2.6 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) PAN_3 PF08277.12 KXZ42181.1 - 0.39 10.6 4.7 4.5 7.2 0.0 3.1 4 0 0 4 4 4 0 PAN-like domain KDZ PF18758.1 KXZ42182.1 - 5.2e-26 91.6 0.2 1e-25 90.7 0.1 1.5 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase HalX PF08663.10 KXZ42182.1 - 3.6 8.0 5.7 2.5 8.5 0.3 2.9 3 0 0 3 3 3 0 HalX domain Aconitase PF00330.20 KXZ42184.1 - 2e-140 468.8 0.0 2.6e-140 468.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXZ42184.1 - 5.5e-45 152.9 0.0 9.7e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DSBA PF01323.20 KXZ42184.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain FA_desaturase_2 PF03405.14 KXZ42185.1 - 6.8e-131 436.0 0.0 7.9e-131 435.7 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 KXZ42185.1 - 0.038 14.4 0.0 9.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Rubrerythrin FAD_binding_3 PF01494.19 KXZ42186.1 - 9.4e-63 212.6 0.2 1.1e-24 87.4 0.2 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXZ42186.1 - 0.00022 21.4 0.1 0.0011 19.1 0.1 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ42186.1 - 0.00044 19.6 0.0 0.0011 18.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ42186.1 - 0.0087 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ42186.1 - 0.022 14.0 0.1 0.022 14.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KXZ42186.1 - 0.049 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXZ42186.1 - 0.33 10.0 3.8 0.62 9.0 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein IMS PF00817.20 KXZ42187.1 - 3.5e-09 36.8 0.0 5.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXZ42187.1 - 0.042 14.5 0.0 0.18 12.5 0.0 2.0 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain SCO1-SenC PF02630.14 KXZ42188.1 - 5.6e-47 159.0 0.0 8.6e-47 158.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KXZ42188.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXZ42188.1 - 0.0036 17.6 0.0 0.0074 16.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like CHIPS PF11434.8 KXZ42188.1 - 0.046 13.6 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS TPH PF13868.6 KXZ42191.1 - 0.00095 17.8 103.5 0.00095 17.8 103.5 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Cu_bind_like PF02298.17 KXZ42192.1 - 2.9e-12 46.4 1.4 5.1e-07 29.6 0.3 2.2 2 0 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.20 KXZ42192.1 - 0.0053 17.2 3.5 0.0098 16.3 0.7 2.1 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KXZ42193.1 - 1.6e-08 34.4 0.2 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.20 KXZ42193.1 - 0.011 16.1 0.8 0.68 10.4 0.2 2.2 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family DUF2177 PF09945.9 KXZ42194.1 - 1.9e-26 92.6 4.4 2.4e-26 92.3 4.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2177) Ammonium_transp PF00909.21 KXZ42195.1 - 1.9e-111 372.6 24.6 2.5e-111 372.2 24.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Aldo_ket_red PF00248.21 KXZ42197.1 - 9.7e-19 67.6 0.0 1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SH3_16 PF18348.1 KXZ42197.1 - 0.07 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Phytochelatin PF05023.14 KXZ42198.1 - 8.3e-73 244.1 0.0 1.2e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase APG5 PF04106.12 KXZ42198.1 - 1.5e-21 77.1 0.0 2.8e-19 69.6 0.0 2.8 1 1 0 1 1 1 1 Autophagy protein Apg5 Peptidase_C39_2 PF13529.6 KXZ42198.1 - 0.13 12.8 0.0 0.43 11.1 0.0 1.8 1 1 0 1 1 1 0 Peptidase_C39 like family Aconitase PF00330.20 KXZ42199.1 - 4.7e-138 461.0 0.0 5.9e-138 460.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXZ42199.1 - 3.8e-43 147.0 0.0 6.2e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Lipoprotein_1 PF00820.19 KXZ42199.1 - 0.31 10.1 0.0 0.5 9.4 0.0 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein Ank_2 PF12796.7 KXZ42200.1 - 1.1e-08 35.5 1.8 0.00061 20.3 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42200.1 - 1.6e-06 28.6 10.1 2.2 9.0 0.1 7.0 7 1 0 7 7 7 3 Ankyrin repeats (many copies) DJ-1_PfpI PF01965.24 KXZ42200.1 - 0.11 12.3 0.1 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 DJ-1/PfpI family Ank_4 PF13637.6 KXZ42201.1 - 2.1e-06 28.1 3.4 3.9 8.2 0.0 5.8 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42201.1 - 0.00011 22.3 0.8 56 4.8 0.0 6.3 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 KXZ42201.1 - 0.00021 21.8 0.8 3.2 8.4 0.0 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) HTH_39 PF14090.6 KXZ42201.1 - 0.014 15.1 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Ank_2 PF12796.7 KXZ42202.1 - 0.00028 21.4 0.0 0.00059 20.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42202.1 - 0.00073 20.1 0.1 0.031 14.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ42202.1 - 0.01 16.2 0.0 5.2 7.5 0.1 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ42203.1 - 7.6e-08 32.8 2.8 0.9 10.2 0.0 5.2 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42203.1 - 2.8e-06 27.2 1.5 39 5.3 0.0 6.0 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 KXZ42203.1 - 2.1e-05 25.0 1.2 0.17 12.5 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) HTH_39 PF14090.6 KXZ42203.1 - 0.01 15.5 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Defensin_4 PF07936.12 KXZ42203.1 - 0.15 12.0 0.5 5.2 7.0 0.1 3.0 3 0 0 3 3 3 0 Potassium-channel blocking toxin MSC PF09402.10 KXZ42204.1 - 0.045 13.2 0.3 0.062 12.8 0.3 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Peptidase_M11 PF05548.11 KXZ42205.1 - 2.2e-13 50.0 0.0 2.5e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Gametolysin peptidase M11 DUF4262 PF14081.6 KXZ42207.1 - 0.029 14.6 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) Peptidase_C48 PF02902.19 KXZ42209.1 - 3.7e-14 53.1 0.0 2.1e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PhyH PF05721.13 KXZ42209.1 - 0.047 13.9 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) CPT PF07931.12 KXZ42209.1 - 0.22 11.4 0.8 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Ank_2 PF12796.7 KXZ42210.1 - 2.4e-43 146.6 12.0 1.6e-15 57.5 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42210.1 - 1.2e-29 102.3 0.4 1.1e-11 45.1 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42210.1 - 4.7e-29 99.5 6.4 2.2e-07 31.0 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KXZ42210.1 - 1.2e-27 92.9 0.1 2.8e-06 27.2 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXZ42210.1 - 2.4e-25 88.3 5.7 2e-07 31.1 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) WHEP-TRS PF00458.20 KXZ42210.1 - 0.036 14.2 0.4 6.2 7.1 0.0 3.1 3 0 0 3 3 3 0 WHEP-TRS domain VWA_3_C PF18571.1 KXZ42210.1 - 3.3 7.6 5.8 66 3.5 0.1 3.7 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Ank_2 PF12796.7 KXZ42211.1 - 4.1e-27 94.6 2.0 8.8e-14 51.9 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42211.1 - 1.4e-25 89.4 0.9 4.3e-10 39.9 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42211.1 - 4.6e-24 83.7 3.8 3.5e-08 33.5 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KXZ42211.1 - 9.5e-20 68.6 0.1 4.5e-05 23.5 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXZ42211.1 - 2.8e-16 59.4 5.9 2.3e-06 27.7 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) IlvN PF07991.12 KXZ42211.1 - 0.01 15.4 3.3 0.78 9.3 0.3 2.7 1 1 2 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UBA PF00627.31 KXZ42211.1 - 0.21 11.5 12.0 8.1 6.5 0.3 3.9 4 0 0 4 4 4 0 UBA/TS-N domain Pkinase PF00069.25 KXZ42212.1 - 3.4e-38 131.5 0.0 1.7e-30 106.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 KXZ42212.1 - 3.7e-14 53.1 0.0 4e-08 33.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KXZ42212.1 - 4.8e-12 45.7 0.0 1.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_4 PF13637.6 KXZ42212.1 - 1.8e-09 38.0 0.0 1.8e-06 28.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42212.1 - 6.4e-09 35.3 0.1 0.00049 20.3 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KXZ42212.1 - 1.9e-08 34.4 0.0 3.5e-06 27.2 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42212.1 - 4.1e-05 23.8 2.7 0.0037 17.7 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeat APH PF01636.23 KXZ42212.1 - 0.029 14.3 0.4 0.064 13.2 0.2 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ42213.1 - 1.4e-12 47.5 0.0 1.5e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42213.1 - 0.0001 21.7 0.0 0.00012 21.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KXZ42213.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXZ42213.1 - 0.023 13.5 0.0 0.027 13.3 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXZ42213.1 - 0.04 13.8 0.1 0.053 13.4 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXZ42213.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KXZ42214.1 - 0.0054 16.0 0.0 0.006 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ42215.1 - 7.8e-36 123.7 0.0 6.1e-33 114.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ42215.1 - 3.4e-32 111.9 0.0 5e-29 101.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ42215.1 - 0.0066 16.4 1.7 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ42215.1 - 0.056 12.8 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HD_3 PF13023.6 KXZ42217.1 - 7.6e-42 143.0 0.1 9.3e-42 142.7 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KXZ42217.1 - 1.4e-11 44.5 0.3 2.4e-11 43.7 0.3 1.4 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KXZ42217.1 - 0.00021 21.5 0.4 0.00043 20.5 0.4 1.5 1 1 0 1 1 1 1 HD domain Peptidase_S41 PF03572.18 KXZ42218.1 - 4.2e-45 153.3 0.0 5.8e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 KXZ42218.1 - 5.9e-09 35.6 1.4 1.9e-08 34.0 0.1 2.6 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 KXZ42218.1 - 1.2e-06 28.8 0.0 2.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ42218.1 - 1.2e-05 25.5 0.0 3.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF3551 PF12071.8 KXZ42218.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3551) WD40 PF00400.32 KXZ42219.1 - 1.5e-16 60.4 14.0 0.11 13.4 0.1 9.1 9 0 0 9 9 9 5 WD domain, G-beta repeat BACK PF07707.15 KXZ42220.1 - 0.008 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch MaoC_dehydratas PF01575.19 KXZ42221.1 - 1.1e-28 99.2 0.0 1.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain DUF3395 PF11875.8 KXZ42222.1 - 5.5e-32 110.8 0.0 1.6e-31 109.3 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KXZ42222.1 - 7.4e-22 77.3 2.2 7.4e-22 77.3 2.2 1.6 2 0 0 2 2 2 1 DnaJ domain DUF3053 PF11254.8 KXZ42222.1 - 0.39 10.3 2.9 0.28 10.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) DUF667 PF05018.13 KXZ42223.1 - 6.5e-20 71.6 0.0 2.2e-18 66.6 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF667) OCRE PF17780.1 KXZ42223.1 - 0.019 15.0 1.0 0.033 14.2 1.0 1.3 1 0 0 1 1 1 0 OCRE domain SufE PF02657.15 KXZ42224.1 - 3.8e-36 123.6 0.0 5.9e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 KXZ42224.1 - 5.7e-30 103.4 0.3 8.7e-30 102.8 0.3 1.3 1 0 0 1 1 1 1 BolA-like protein DUF3306 PF11748.8 KXZ42224.1 - 0.35 11.8 4.2 0.51 11.2 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Peptidase_C2 PF00648.21 KXZ42225.1 - 1e-18 67.4 0.1 1.7e-18 66.7 0.0 1.4 2 0 0 2 2 2 1 Calpain family cysteine protease zf-RING_2 PF13639.6 KXZ42226.1 - 3.5e-11 43.3 7.3 4.8e-11 42.8 7.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ42226.1 - 6.5e-10 38.7 7.4 9.1e-10 38.2 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ42226.1 - 9.6e-09 35.0 6.0 1.3e-08 34.5 6.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ42226.1 - 4.4e-08 33.0 4.4 6e-08 32.5 4.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXZ42226.1 - 1.3e-07 31.4 4.8 1.8e-07 30.9 4.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ42226.1 - 6.5e-07 29.5 4.2 1.1e-06 28.8 4.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXZ42226.1 - 9.9e-07 28.7 5.7 1.8e-06 27.8 5.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXZ42226.1 - 2.5e-05 23.9 4.0 3.5e-05 23.4 2.6 1.8 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 KXZ42226.1 - 0.00012 21.9 6.1 0.0002 21.2 6.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXZ42226.1 - 0.042 13.9 1.9 0.066 13.3 1.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXZ42226.1 - 0.054 13.7 7.1 0.14 12.3 7.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXZ42226.1 - 0.06 13.1 5.6 0.085 12.7 5.6 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UBZ_FAAP20 PF15750.5 KXZ42226.1 - 0.27 11.2 1.7 24 5.0 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DUF1272 PF06906.11 KXZ42226.1 - 0.39 10.9 4.6 0.6 10.2 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) SRCR PF00530.18 KXZ42227.1 - 1.1e-05 25.9 0.0 0.0025 18.3 0.0 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ42227.1 - 0.0051 17.3 0.1 0.011 16.2 0.0 1.6 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain NADH-u_ox-rdase PF10785.9 KXZ42227.1 - 0.11 13.2 0.2 0.18 12.5 0.2 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit SRCR PF00530.18 KXZ42231.1 - 0.00023 21.6 0.0 0.033 14.7 0.0 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain 14-3-3 PF00244.20 KXZ42233.1 - 3.9e-26 91.9 0.1 4.4e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein 14-3-3 PF00244.20 KXZ42234.1 - 7.3e-56 189.2 0.6 8.1e-56 189.0 0.6 1.0 1 0 0 1 1 1 1 14-3-3 protein 14-3-3 PF00244.20 KXZ42235.1 - 7.7e-36 123.7 1.7 8.8e-36 123.5 1.7 1.0 1 0 0 1 1 1 1 14-3-3 protein PMEI PF04043.15 KXZ42235.1 - 0.0072 16.7 0.5 0.0086 16.4 0.5 1.1 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Dam PF05869.11 KXZ42236.1 - 0.029 13.9 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) VirE_N PF08800.10 KXZ42236.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 VirE N-terminal domain Phage_integrase PF00589.22 KXZ42237.1 - 0.032 14.0 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family 14-3-3 PF00244.20 KXZ42238.1 - 1.3e-30 106.6 0.2 1.5e-30 106.4 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein HTH_50 PF18024.1 KXZ42238.1 - 0.042 13.5 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain p450 PF00067.22 KXZ42239.1 - 1.2e-76 258.3 0.0 1.7e-76 257.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PTPlike_phytase PF14566.6 KXZ42240.1 - 1.6e-07 31.6 0.0 1.9e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate ATG16 PF08614.11 KXZ42242.1 - 0.013 15.8 0.2 0.015 15.5 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HsbA PF12296.8 KXZ42242.1 - 0.02 15.3 0.5 0.028 14.9 0.5 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A GramPos_pilinD1 PF16555.5 KXZ42242.1 - 0.063 13.5 0.2 0.082 13.1 0.2 1.3 1 1 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain DUF2383 PF09537.10 KXZ42242.1 - 0.076 13.4 0.4 0.18 12.1 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2383) DUF533 PF04391.12 KXZ42242.1 - 0.082 12.5 4.6 0.13 11.8 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF533) AAA_13 PF13166.6 KXZ42242.1 - 0.099 11.3 0.1 0.12 11.1 0.1 1.0 1 0 0 1 1 1 0 AAA domain ECH_2 PF16113.5 KXZ42243.1 - 0.0038 16.8 1.3 0.0093 15.5 1.3 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SLX9 PF15341.6 KXZ42243.1 - 0.0092 16.4 9.1 0.018 15.4 0.6 2.6 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 FIN1 PF17300.2 KXZ42243.1 - 0.33 10.4 1.2 0.75 9.3 1.2 1.5 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Glyco_trans_1_2 PF13524.6 KXZ42243.1 - 0.48 10.9 6.8 12 6.3 0.1 3.9 3 1 0 3 3 3 0 Glycosyl transferases group 1 MutS_III PF05192.18 KXZ42243.1 - 0.98 9.6 3.8 50 4.0 0.0 2.4 2 0 0 2 2 2 0 MutS domain III NPV_P10 PF05531.12 KXZ42243.1 - 1.1 9.8 13.5 0.27 11.7 2.4 3.8 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Flg_hook PF02120.16 KXZ42243.1 - 2.1 8.3 14.1 5.2 7.0 1.5 2.8 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK ADK PF00406.22 KXZ42244.1 - 8e-235 769.4 0.0 1.1e-45 155.5 0.0 5.1 5 0 0 5 5 5 5 Adenylate kinase AAA_17 PF13207.6 KXZ42244.1 - 7.6e-170 557.4 4.7 2.2e-32 112.3 0.0 5.2 5 0 0 5 5 5 5 AAA domain AAA_18 PF13238.6 KXZ42244.1 - 8.4e-38 129.9 0.0 1.3e-05 25.7 0.0 5.6 5 0 0 5 5 5 5 AAA domain AAA_33 PF13671.6 KXZ42244.1 - 5.6e-30 104.4 0.0 0.00035 20.8 0.0 6.7 5 5 0 5 5 5 5 AAA domain Thymidylate_kin PF02223.17 KXZ42244.1 - 4.6e-15 55.8 18.5 2.3 7.9 0.1 10.1 10 0 0 10 10 10 3 Thymidylate kinase AAA_19 PF13245.6 KXZ42244.1 - 1.8e-13 51.0 0.6 1.1 9.6 0.0 5.4 5 0 0 5 5 5 4 AAA domain Zeta_toxin PF06414.12 KXZ42244.1 - 1.4e-12 47.3 3.3 0.86 8.8 0.0 5.6 5 0 0 5 5 5 5 Zeta toxin Ploopntkinase3 PF18751.1 KXZ42244.1 - 3.9e-09 36.7 0.1 11 5.9 0.0 5.4 5 0 0 5 5 5 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 KXZ42244.1 - 5.1e-09 36.5 4.2 6.8 7.0 0.0 6.2 5 0 0 5 5 5 0 AAA domain AAA_30 PF13604.6 KXZ42244.1 - 6.6e-09 35.8 0.2 6.1 6.5 0.0 5.2 5 0 0 5 5 5 0 AAA domain NB-ARC PF00931.22 KXZ42244.1 - 5e-08 32.4 0.3 6.7 5.8 0.0 5.2 5 0 0 5 5 5 0 NB-ARC domain AAA PF00004.29 KXZ42244.1 - 1.9e-07 31.6 10.9 6.8 7.1 0.0 7.1 5 5 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KXZ42244.1 - 1.9e-06 27.8 0.1 22 4.7 0.0 5.7 5 0 0 5 5 5 0 Cytidylate kinase NTPase_1 PF03266.15 KXZ42244.1 - 2e-06 27.8 8.3 6.8 6.6 0.1 5.3 5 0 0 5 5 5 0 NTPase ABC_tran PF00005.27 KXZ42244.1 - 2.5e-06 28.1 0.0 29 5.2 0.0 5.5 5 0 0 5 5 5 0 ABC transporter AAA_28 PF13521.6 KXZ42244.1 - 7.4e-06 26.3 5.8 14 5.9 0.1 5.8 5 0 0 5 5 5 0 AAA domain ATP_bind_1 PF03029.17 KXZ42244.1 - 1.5e-05 25.0 7.2 13 5.4 0.0 5.4 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KXZ42244.1 - 6e-05 22.9 0.4 39 3.9 0.0 5.1 5 0 0 5 5 5 0 AAA domain MeaB PF03308.16 KXZ42244.1 - 6.9e-05 22.0 0.8 26 3.7 0.0 5.0 5 0 0 5 5 5 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2710 PF10921.8 KXZ42244.1 - 0.00055 20.3 0.0 30 5.1 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2710) NMT1_3 PF16868.5 KXZ42244.1 - 0.0011 18.4 0.1 16 4.8 0.0 5.2 6 0 0 6 6 5 0 NMT1-like family VWA_N PF08399.11 KXZ42244.1 - 0.0021 18.5 0.2 10 6.7 0.0 4.4 5 0 0 5 5 5 0 VWA N-terminal Flavodoxin_3 PF12641.7 KXZ42244.1 - 0.0031 17.2 0.1 31 4.2 0.0 4.5 5 0 0 5 5 5 0 Flavodoxin domain Hydin_ADK PF17213.3 KXZ42244.1 - 0.0041 17.4 0.0 1.1e+02 3.0 0.0 4.9 5 0 0 5 5 5 0 Hydin Adenylate kinase-like domain DUF2075 PF09848.9 KXZ42244.1 - 0.01 15.1 7.5 42 3.2 0.0 5.0 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KXZ42244.1 - 0.011 15.1 2.9 43 3.3 0.0 4.9 5 0 0 5 5 5 0 KaiC Dfp1_Him1_M PF08630.10 KXZ42244.1 - 0.013 15.7 1.6 1.1e+02 3.0 0.0 4.8 5 0 0 5 5 5 0 Dfp1/Him1, central region ASPRs PF17641.2 KXZ42244.1 - 0.028 14.7 2.1 2.3e+02 2.0 0.0 4.8 5 0 0 5 5 5 0 Ancylostoma-associated secreted protein related RBD PF02196.15 KXZ42244.1 - 0.042 13.9 1.4 71 3.6 0.0 4.6 5 0 0 5 5 5 0 Raf-like Ras-binding domain ChaB PF06150.12 KXZ42244.1 - 0.089 13.4 0.0 4.3e+02 1.6 0.0 4.6 4 0 0 4 4 4 0 ChaB TrwB_AAD_bind PF10412.9 KXZ42244.1 - 0.22 10.4 0.0 1.2e+02 1.4 0.0 4.0 5 0 0 5 5 5 0 Type IV secretion-system coupling protein DNA-binding domain NYD-SP28 PF14772.6 KXZ42244.1 - 1.1 9.3 6.3 1.3e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Sperm tail BRD4_CDT PF17105.5 KXZ42245.1 - 0.45 10.2 3.2 0.63 9.7 3.2 1.2 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 ATP1G1_PLM_MAT8 PF02038.16 KXZ42246.1 - 0.19 11.2 0.2 0.96 8.9 0.0 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Tubulin PF00091.25 KXZ42248.1 - 4.9e-67 225.9 0.0 6.7e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXZ42248.1 - 4.3e-51 172.3 0.0 6.9e-51 171.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXZ42248.1 - 0.0058 16.3 0.0 0.023 14.4 0.0 2.1 3 0 0 3 3 3 1 Tubulin domain WW PF00397.26 KXZ42249.1 - 0.00023 21.2 1.2 0.00046 20.2 1.2 1.6 1 0 0 1 1 1 1 WW domain AbiEi_4 PF13338.6 KXZ42249.1 - 0.005 17.0 2.2 0.027 14.6 2.2 2.4 1 1 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin Tom22 PF04281.13 KXZ42249.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 VCBS PF13517.6 KXZ42251.1 - 1.5e-12 47.9 0.9 1.4e-07 32.0 0.2 2.6 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KXZ42251.1 - 8.1e-07 29.1 11.3 0.0029 17.7 1.8 3.7 3 0 0 3 3 3 3 FG-GAP repeat Itfg2 PF15907.5 KXZ42251.1 - 0.00012 21.3 0.1 1 8.3 0.1 3.5 3 1 0 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 PQQ PF01011.21 KXZ42251.1 - 0.00012 21.8 0.6 4.1 7.5 0.1 4.0 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 KXZ42251.1 - 0.00016 22.0 11.3 0.17 12.4 0.7 5.0 5 0 0 5 5 5 2 PQQ-like domain PQQ_2 PF13360.6 KXZ42251.1 - 0.00034 20.3 0.5 0.00065 19.4 0.5 1.5 1 1 0 1 1 1 1 PQQ-like domain EF-hand_5 PF13202.6 KXZ42251.1 - 0.093 12.3 2.7 26 4.6 0.0 3.4 3 0 0 3 3 3 0 EF hand Spindle_Spc25 PF08234.12 KXZ42251.1 - 0.22 11.8 0.0 0.52 10.6 0.0 1.6 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 Kelch_4 PF13418.6 KXZ42252.1 - 9.5e-36 121.6 4.1 3.6e-07 30.1 0.0 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ42252.1 - 7.2e-32 108.8 3.8 5.1e-08 32.7 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KXZ42252.1 - 2.6e-25 88.1 8.7 3e-07 30.6 0.1 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KXZ42252.1 - 4.7e-24 83.7 1.4 1.8e-06 27.4 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KXZ42252.1 - 1.4e-23 82.4 5.6 1.7e-06 28.1 0.0 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KXZ42252.1 - 2.3e-17 62.2 2.2 0.0016 18.3 0.1 5.5 5 0 0 5 5 5 4 Kelch motif zf-C3HC4_3 PF13920.6 KXZ42252.1 - 1e-07 31.7 11.4 1.8e-07 30.9 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 KXZ42252.1 - 1.4e-05 25.2 2.9 1.4e-05 25.2 2.9 2.5 2 1 1 3 3 3 1 K-box region TPR_MLP1_2 PF07926.12 KXZ42252.1 - 0.016 15.3 1.4 0.016 15.3 1.4 3.2 3 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein zf-C3HC4 PF00097.25 KXZ42252.1 - 0.016 15.0 9.0 0.03 14.2 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ42252.1 - 0.039 13.8 8.3 0.076 12.9 8.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXZ42252.1 - 0.067 13.1 14.1 0.14 12.1 14.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ42252.1 - 0.22 11.5 12.6 0.43 10.6 12.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2721 PF11026.8 KXZ42252.1 - 0.44 10.4 0.0 0.44 10.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) zf-RING_2 PF13639.6 KXZ42252.1 - 2.9 8.3 12.6 5.9 7.3 12.6 1.6 1 0 0 1 1 1 0 Ring finger domain HECT PF00632.25 KXZ42255.1 - 6.3e-29 101.4 0.0 1.3e-13 51.2 0.0 2.7 2 1 0 2 2 2 2 HECT-domain (ubiquitin-transferase) TilS PF09179.11 KXZ42255.1 - 0.026 15.0 1.7 0.13 12.8 0.1 3.2 2 0 0 2 2 2 0 TilS substrate binding domain HTH_32 PF13565.6 KXZ42256.1 - 0.063 13.9 0.1 0.44 11.2 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Asp_protease_2 PF13650.6 KXZ42259.1 - 0.016 15.8 0.0 0.037 14.7 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease Peptidase_A2E PF12382.8 KXZ42259.1 - 0.029 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase Phage_integrase PF00589.22 KXZ42260.1 - 0.0039 17.0 0.3 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family Dam PF05869.11 KXZ42260.1 - 0.012 15.2 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) RicinB_lectin_2 PF14200.6 KXZ42261.1 - 2.2e-33 114.8 13.6 7.7e-19 68.2 0.2 4.1 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like VOMI PF03762.17 KXZ42261.1 - 8.1e-33 113.9 3.6 1.4e-32 113.2 0.5 2.3 2 0 0 2 2 2 1 Vitelline membrane outer layer protein I (VOMI) Ricin_B_lectin PF00652.22 KXZ42261.1 - 5.9e-27 94.4 5.8 8.5e-18 64.8 0.5 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KXZ42261.1 - 4.8e-06 26.2 0.9 4.8e-06 26.2 0.9 2.2 1 1 1 2 2 2 1 Cytolethal distending toxin A/C domain EF-hand_1 PF00036.32 KXZ42262.1 - 0.0003 20.1 0.1 0.00054 19.3 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ42262.1 - 0.0011 18.4 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ42262.1 - 0.0014 18.4 0.9 0.0025 17.6 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KXZ42262.1 - 0.021 15.3 0.0 0.025 15.0 0.0 1.3 1 1 0 1 1 1 0 EF-hand domain pair Rhomboid PF01694.22 KXZ42263.1 - 3.5e-06 27.1 2.9 3.5e-06 27.1 2.9 2.6 3 0 0 3 3 3 1 Rhomboid family MIR PF02815.19 KXZ42264.1 - 0.00086 19.2 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 KXZ42264.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Ephrin_rec_like PF07699.13 KXZ42265.1 - 4.6e-05 23.1 1.6 0.001 18.8 0.2 2.6 2 0 0 2 2 2 1 Putative ephrin-receptor like PAN_4 PF14295.6 KXZ42265.1 - 0.002 18.0 2.1 0.0064 16.4 2.1 1.9 1 0 0 1 1 1 1 PAN domain MMS1_N PF10433.9 KXZ42266.1 - 4.1e-72 243.4 0.0 5.1e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4586 PF15239.6 KXZ42267.1 - 2.4e-06 28.0 0.0 5e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) DUF4586 PF15239.6 KXZ42268.1 - 1.7e-06 28.4 2.3 1.9e-06 28.3 1.8 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase_Tyr PF07714.17 KXZ42269.1 - 0.0021 17.4 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SRP-alpha_N PF04086.13 KXZ42269.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 KXZ42269.1 - 0.21 10.3 1.2 0.24 10.1 1.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Helitron_like_N PF14214.6 KXZ42273.1 - 8.2e-12 45.7 0.0 1.6e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 KXZ42273.1 - 0.00095 18.9 0.0 0.0063 16.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ42273.1 - 0.003 17.9 0.0 0.007 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ42273.1 - 0.045 14.3 0.0 3.3 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KXZ42273.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 KXZ42273.1 - 0.086 13.1 0.1 0.85 9.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain CYTL1 PF15153.6 KXZ42274.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytokine-like protein 1 Helitron_like_N PF14214.6 KXZ42275.1 - 1.3e-11 45.1 0.0 2.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 KXZ42275.1 - 0.00079 19.2 0.0 0.0066 16.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ42275.1 - 0.0023 18.3 0.0 0.0063 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ42275.1 - 0.04 14.2 0.1 0.23 11.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 KXZ42275.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 KXZ42275.1 - 0.22 12.1 0.0 3.4 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain LRR_4 PF12799.7 KXZ42276.1 - 0.18 12.3 5.1 1.5 9.4 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ42276.1 - 1 9.2 5.6 32 4.4 0.0 3.2 2 1 1 3 3 3 0 Leucine rich repeat p450 PF00067.22 KXZ42279.1 - 3.1e-21 75.7 0.0 3.6e-19 68.9 0.0 2.6 1 1 1 2 2 2 1 Cytochrome P450 Ank_2 PF12796.7 KXZ42280.1 - 2.9e-19 69.4 0.0 1.4e-08 35.2 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ42280.1 - 4e-15 55.5 0.9 0.00076 19.8 0.0 5.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ42280.1 - 4.5e-14 52.6 0.7 3.6e-07 30.6 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ42280.1 - 9.4e-11 41.7 0.4 2.2e-08 34.2 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42280.1 - 1.2e-10 40.6 0.4 0.1 13.2 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat MIB_HERC2 PF06701.13 KXZ42280.1 - 0.00081 19.6 1.1 1.7 8.9 0.8 3.5 3 0 0 3 3 3 1 Mib_herc2 DM13 PF10517.9 KXZ42283.1 - 9.8e-109 357.1 0.0 1.7e-14 54.3 0.0 8.3 8 0 0 8 8 8 8 Electron transfer DM13 DOMON PF03351.17 KXZ42283.1 - 4.5e-11 43.0 0.0 7.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 DOMON domain DUF3242 PF11586.8 KXZ42283.1 - 0.016 14.9 0.0 25 4.6 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3242) Ribonuc_red_lgC PF02867.15 KXZ42284.1 - 5.2e-10 38.5 0.0 0.0015 17.2 0.0 3.2 2 1 1 3 3 3 3 Ribonucleotide reductase, barrel domain RNR_Alpha PF17975.1 KXZ42284.1 - 0.00064 20.2 0.1 0.0017 18.8 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Filament PF00038.21 KXZ42285.1 - 0.0024 17.5 2.8 0.13 11.9 0.0 2.1 2 0 0 2 2 2 2 Intermediate filament protein DivIC PF04977.15 KXZ42285.1 - 0.46 10.3 2.5 8.8 6.2 0.6 2.4 2 0 0 2 2 2 0 Septum formation initiator kleA_kleC PF17383.2 KXZ42285.1 - 2.1 8.7 18.8 0.1 12.9 6.9 2.9 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Pkinase PF00069.25 KXZ42286.1 - 8.8e-14 51.5 0.0 1.1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42286.1 - 2.4e-09 36.9 0.0 2.9e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ42287.1 - 9e-06 25.2 0.0 2.3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42287.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Fasciclin PF02469.22 KXZ42288.1 - 7.5e-18 65.0 0.0 9e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain TPR_2 PF07719.17 KXZ42289.1 - 3.2e-15 54.9 6.7 6.1e-06 25.9 0.0 4.9 5 1 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ42289.1 - 2.8e-13 49.1 6.5 1.9e-07 30.6 0.0 4.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ42289.1 - 7.3e-13 48.0 5.1 1.8e-06 27.5 0.7 5.0 2 2 3 5 5 5 3 TPR repeat TPR_19 PF14559.6 KXZ42289.1 - 7.5e-12 45.6 9.9 7.8e-06 26.3 0.1 4.6 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42289.1 - 1e-11 44.6 17.3 0.018 15.8 2.6 6.0 2 1 4 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ42289.1 - 4.4e-11 42.4 0.8 0.0027 18.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ42289.1 - 5e-11 42.7 11.0 2.2e-07 31.1 0.9 3.6 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ42289.1 - 2.1e-10 41.0 19.8 5.5e-06 26.9 0.8 4.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ42289.1 - 2e-08 34.3 9.8 0.00015 21.8 0.0 4.2 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ42289.1 - 4.2e-06 26.5 2.6 0.0015 18.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ42289.1 - 1.1e-05 25.1 6.0 0.049 13.0 0.0 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 KXZ42289.1 - 3.8e-05 23.4 2.3 0.29 11.3 0.1 4.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ42289.1 - 0.00014 21.6 11.3 0.074 12.9 0.9 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ42289.1 - 0.0038 17.7 20.0 1.9 9.4 5.5 5.1 5 1 1 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ42289.1 - 0.0059 16.8 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 HemY_N PF07219.13 KXZ42289.1 - 0.0094 16.1 7.3 2.2 8.5 0.1 3.6 2 1 1 4 4 4 1 HemY protein N-terminus NARP1 PF12569.8 KXZ42289.1 - 0.017 14.1 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 KXZ42289.1 - 0.02 14.1 5.4 0.21 10.8 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXZ42289.1 - 0.12 12.0 7.7 4.6 6.9 0.1 3.2 1 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KXZ42289.1 - 0.14 12.9 9.0 33 5.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 KXZ42289.1 - 0.24 11.5 3.1 1.7 8.7 0.3 2.8 1 1 2 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_20 PF14561.6 KXZ42289.1 - 0.52 10.7 3.5 6.9 7.1 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Tam41_Mmp37 PF09139.11 KXZ42290.1 - 7.8e-60 203.0 0.0 8.7e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial TLD PF07534.16 KXZ42291.1 - 1.8e-31 109.2 0.0 2.7e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 TLD YHYH PF14240.6 KXZ42292.1 - 3.8e-12 46.6 1.3 3.8e-12 46.6 1.3 2.4 1 1 1 2 2 2 2 YHYH protein ATG16 PF08614.11 KXZ42293.1 - 0.12 12.6 0.0 0.12 12.6 0.0 10.8 10 2 2 12 12 12 0 Autophagy protein 16 (ATG16) Salt_tol_Pase PF09506.10 KXZ42293.1 - 2.6 6.7 5.2 5 5.8 5.2 1.4 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) GED PF02212.18 KXZ42293.1 - 3.1 8.0 6.4 2 8.6 3.3 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain MRP-S25 PF13741.6 KXZ42295.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 DSPc PF00782.20 KXZ42296.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXZ42296.1 - 0.0003 20.8 0.1 0.00089 19.3 0.1 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXZ42296.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KXZ42296.1 - 0.0037 17.0 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KXZ42296.1 - 0.068 13.3 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Rhodanese PF00581.20 KXZ42296.1 - 0.085 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain Sybindin PF04099.12 KXZ42297.1 - 3.4e-38 130.8 0.4 8.4e-36 123.0 0.4 2.4 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXZ42297.1 - 1.3e-06 28.5 0.0 1.8e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Histidinol_dh PF00815.20 KXZ42299.1 - 2.4e-163 543.9 0.1 2.7e-163 543.8 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Fibrillarin PF01269.17 KXZ42300.1 - 3.7e-109 363.1 0.0 4.3e-109 362.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KXZ42300.1 - 0.00031 20.5 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 KXZ42300.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KXZ42300.1 - 0.053 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KXZ42300.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Peptidase_S8 PF00082.22 KXZ42303.1 - 6.4e-46 157.0 0.0 3e-33 115.4 0.0 3.1 2 1 1 3 3 3 2 Subtilase family fn3_5 PF06280.12 KXZ42303.1 - 0.1 13.3 0.2 0.36 11.5 0.0 2.1 2 0 0 2 2 2 0 Fn3-like domain DUF3829 PF12889.7 KXZ42304.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF1043 PF06295.12 KXZ42305.1 - 6.2e-06 26.2 5.5 9.1e-06 25.7 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) DUF1993 PF09351.10 KXZ42305.1 - 0.011 15.9 4.4 0.015 15.4 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DASH_Spc34 PF08657.10 KXZ42305.1 - 0.015 15.1 7.0 0.018 14.9 7.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 eIF3_subunit PF08597.10 KXZ42305.1 - 0.022 14.7 14.2 0.028 14.4 14.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TMPIT PF07851.13 KXZ42305.1 - 0.022 14.0 11.5 0.031 13.5 11.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 KXZ42305.1 - 0.031 14.6 15.4 0.045 14.1 15.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MMR1 PF08505.10 KXZ42305.1 - 0.037 14.3 3.2 0.038 14.3 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Exonuc_VII_L PF02601.15 KXZ42305.1 - 0.05 13.2 8.9 0.055 13.0 8.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KXZ42305.1 - 0.12 11.0 6.5 0.15 10.6 6.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 KXZ42305.1 - 0.14 11.2 9.0 0.15 11.1 9.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 KXZ42305.1 - 0.15 11.6 8.4 0.2 11.3 8.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_11 PF13086.6 KXZ42305.1 - 0.19 11.5 6.3 0.23 11.2 6.3 1.3 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 KXZ42305.1 - 0.2 11.8 3.2 0.21 11.7 3.2 1.2 1 0 0 1 1 1 0 DDHD domain Tox-ODYAM1 PF15642.6 KXZ42305.1 - 0.28 10.1 6.9 0.34 9.8 6.9 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF4746 PF15928.5 KXZ42305.1 - 0.31 10.4 5.2 0.31 10.4 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF16 PF01519.16 KXZ42305.1 - 0.31 11.5 10.1 0.5 10.9 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 KXZ42305.1 - 0.43 8.4 4.1 0.44 8.4 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 KXZ42305.1 - 0.84 8.1 15.3 1 7.8 15.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Presenilin PF01080.17 KXZ42305.1 - 0.88 8.3 4.8 0.85 8.3 4.8 1.1 1 0 0 1 1 1 0 Presenilin ARGLU PF15346.6 KXZ42305.1 - 0.95 9.3 30.1 0.4 10.6 25.9 2.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Peptidase_S49_N PF08496.10 KXZ42305.1 - 0.96 9.5 7.4 1.4 9.0 7.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF724 PF05266.14 KXZ42305.1 - 1.1 9.0 13.6 1.7 8.5 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KXZ42305.1 - 1.4 8.2 13.1 1.8 7.9 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SprA-related PF12118.8 KXZ42305.1 - 1.8 7.6 14.3 2.4 7.2 14.3 1.2 1 0 0 1 1 1 0 SprA-related family LMBR1 PF04791.16 KXZ42305.1 - 2 7.2 3.5 2.1 7.2 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FemAB PF02388.16 KXZ42305.1 - 2.1 7.2 9.7 2.9 6.7 9.7 1.2 1 0 0 1 1 1 0 FemAB family DUF702 PF05142.12 KXZ42305.1 - 2.2 8.7 6.9 3.1 8.3 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) XRN_M PF17846.1 KXZ42305.1 - 2.5 7.0 6.1 3 6.7 6.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain HemX PF04375.14 KXZ42305.1 - 2.7 7.2 19.6 4 6.6 19.6 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CR6_interact PF10147.9 KXZ42305.1 - 4.2 7.0 26.3 32 4.1 0.0 2.2 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TMF_DNA_bd PF12329.8 KXZ42305.1 - 4.7 7.3 23.8 2 8.5 5.1 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding GBP_C PF02841.14 KXZ42305.1 - 6.3 6.1 21.2 11 5.3 21.2 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF2828 PF11443.8 KXZ42305.1 - 6.6 4.7 9.7 7.9 4.4 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Sugarporin_N PF11471.8 KXZ42305.1 - 7 6.7 35.2 1.7 8.7 0.3 4.4 1 1 2 3 3 2 0 Maltoporin periplasmic N-terminal extension Dynamin_N PF00350.23 KXZ42306.1 - 3.9e-05 23.8 0.0 6.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Baculo_PEP_C PF04513.12 KXZ42306.1 - 0.38 10.8 3.9 1.6 8.8 0.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_2 PF07719.17 KXZ42307.1 - 2.9e-09 36.3 9.9 0.0073 16.3 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ42307.1 - 1e-07 31.4 2.0 0.043 13.7 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ42307.1 - 7.8e-07 29.6 21.2 0.0017 19.0 3.2 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ42307.1 - 1.5e-05 24.5 7.7 0.054 13.2 0.2 3.7 3 1 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 KXZ42307.1 - 3.1e-05 24.4 19.2 0.021 15.6 3.0 3.7 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ42307.1 - 0.0001 22.5 13.8 0.028 14.7 0.3 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ42307.1 - 0.0012 19.3 1.6 0.0012 19.3 1.6 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ42307.1 - 0.0023 18.1 7.5 0.0098 16.0 6.4 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ42307.1 - 0.0072 16.3 3.1 0.11 12.6 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ42307.1 - 0.021 15.4 2.4 0.021 15.4 2.4 4.8 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ42307.1 - 0.084 12.8 14.8 0.15 12.0 2.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXZ42307.1 - 0.14 11.9 4.8 2.1 8.0 1.7 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 KXZ42307.1 - 0.17 12.2 1.6 17 6.0 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat BTAD PF03704.17 KXZ42307.1 - 0.21 12.0 7.3 10 6.5 7.3 2.4 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KXZ42307.1 - 0.76 10.5 7.6 32 5.4 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AP2 PF00847.20 KXZ42308.1 - 1.4e-13 50.8 0.5 2.2e-13 50.2 0.5 1.3 1 0 0 1 1 1 1 AP2 domain BAH PF01426.18 KXZ42309.1 - 2.7e-20 72.5 0.2 5.8e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 KXZ42309.1 - 5.5e-09 35.8 7.5 5.5e-09 35.8 7.5 1.6 2 0 0 2 2 2 1 PHD-finger Flu_C_NS2 PF03555.14 KXZ42309.1 - 0.11 12.7 0.1 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) PHD_4 PF16866.5 KXZ42309.1 - 0.13 12.4 7.5 0.26 11.4 7.5 1.5 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 KXZ42309.1 - 0.17 11.5 3.6 0.28 10.8 2.4 2.0 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KXZ42309.1 - 0.3 11.4 8.7 0.52 10.7 8.7 1.4 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.6 KXZ42309.1 - 0.43 10.5 6.2 0.2 11.6 1.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 KXZ42309.1 - 0.5 10.3 4.8 0.14 12.1 1.0 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OST3_OST6 PF04756.13 KXZ42310.1 - 9.9e-56 189.2 0.0 1.2e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family EMP70 PF02990.16 KXZ42311.1 - 6e-173 576.2 19.7 7.3e-173 575.9 19.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 JAB PF01398.21 KXZ42312.1 - 6.4e-15 55.2 0.1 1.2e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TerB_N PF13208.6 KXZ42312.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 TerB N-terminal domain DUF3245 PF11595.8 KXZ42312.1 - 0.13 12.8 0.1 0.25 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Ank_2 PF12796.7 KXZ42313.1 - 1.8e-30 105.3 0.3 2.6e-17 63.2 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Pkinase PF00069.25 KXZ42313.1 - 1.8e-22 80.0 0.0 4.5e-22 78.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ank PF00023.30 KXZ42313.1 - 3.7e-20 71.4 5.3 1.5e-05 25.2 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KXZ42313.1 - 1.8e-18 66.6 0.1 4.4e-10 39.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42313.1 - 1.2e-17 62.2 3.3 0.00036 20.8 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXZ42313.1 - 2.2e-16 59.7 1.3 6.1e-07 29.6 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KXZ42313.1 - 5.8e-13 48.7 0.0 1.3e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KXZ42313.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXZ42313.1 - 0.047 13.6 0.1 0.047 13.6 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ42313.1 - 0.067 12.0 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FKS1_dom1 PF14288.6 KXZ42314.1 - 5.1e-12 46.2 0.0 1.6e-06 28.5 0.1 2.1 2 0 0 2 2 2 2 1,3-beta-glucan synthase subunit FKS1, domain-1 Glucan_synthase PF02364.15 KXZ42315.1 - 3.1e-103 346.6 0.0 1.1e-88 298.4 0.0 3.8 2 2 0 2 2 2 2 1,3-beta-glucan synthase component Pkinase PF00069.25 KXZ42316.1 - 1.1e-20 74.1 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42316.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ42316.1 - 0.0056 16.0 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ42316.1 - 0.034 13.5 3.1 0.067 12.5 3.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 KXZ42317.1 - 2.1e-40 137.2 6.2 8.3e-15 55.2 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ42317.1 - 2.6e-38 128.8 15.2 4.2e-07 30.1 0.2 7.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KXZ42317.1 - 4.5e-37 125.6 5.3 1.2e-08 35.0 0.0 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ42317.1 - 2.2e-34 117.4 4.8 4.3e-09 36.7 0.0 6.1 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42317.1 - 4.6e-29 97.2 0.9 0.00026 21.2 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat DUF2384 PF09722.10 KXZ42317.1 - 0.021 14.8 5.2 0.11 12.5 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) CD36 PF01130.21 KXZ42318.1 - 3.4e-62 210.5 0.0 4.7e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 CD36 family DnaJ PF00226.31 KXZ42319.1 - 1.1e-18 67.1 1.7 5.9e-18 64.7 0.5 2.3 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.16 KXZ42319.1 - 5e-13 48.8 0.0 7.2e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Sec63 Brl domain MSC PF09402.10 KXZ42319.1 - 0.046 13.2 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DivIC PF04977.15 KXZ42320.1 - 0.00019 21.1 17.1 0.034 13.9 7.7 2.3 1 1 1 2 2 2 2 Septum formation initiator Spc7 PF08317.11 KXZ42320.1 - 0.0019 17.2 2.3 0.0026 16.7 2.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KXZ42320.1 - 0.0083 16.3 3.2 0.0083 16.3 3.2 1.5 1 1 0 1 1 1 1 Tropomyosin like Fez1 PF06818.15 KXZ42320.1 - 0.014 15.8 5.0 0.019 15.4 5.0 1.1 1 0 0 1 1 1 0 Fez1 DUF4201 PF13870.6 KXZ42320.1 - 0.025 14.3 4.2 0.033 13.9 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 KXZ42320.1 - 0.063 12.6 11.3 0.079 12.3 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PI3K_P85_iSH2 PF16454.5 KXZ42320.1 - 0.12 12.0 2.9 0.18 11.4 2.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2968 PF11180.8 KXZ42320.1 - 0.15 11.7 19.0 0.32 10.6 19.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) CEP209_CC5 PF16574.5 KXZ42320.1 - 0.18 12.0 4.6 0.26 11.4 4.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 APG6_N PF17675.1 KXZ42320.1 - 0.3 11.6 14.3 1.2 9.6 14.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3584 PF12128.8 KXZ42320.1 - 0.67 7.4 10.3 0.82 7.1 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cep57_CLD_2 PF14197.6 KXZ42320.1 - 1 9.5 10.3 2.6 8.2 0.3 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 YabA PF06156.13 KXZ42320.1 - 1.1 10.0 3.7 3.4 8.4 0.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 KXZ42320.1 - 1.3 9.4 10.7 5.2 7.5 10.7 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0242 PF06785.11 KXZ42320.1 - 1.5 8.8 4.6 2.2 8.3 4.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KXZ42320.1 - 1.9 7.5 6.9 2.6 7.1 6.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TolA_bind_tri PF16331.5 KXZ42320.1 - 2.4 8.3 12.7 0.22 11.6 2.7 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 KXZ42320.1 - 2.8 8.2 9.8 44 4.3 9.8 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 KXZ42320.1 - 6.4 7.2 10.1 1.2 9.5 5.3 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FUSC PF04632.12 KXZ42320.1 - 6.4 5.2 13.8 8.5 4.8 13.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 KXZ42320.1 - 7.6 6.8 8.0 24 5.2 7.3 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain THOC7 PF05615.13 KXZ42320.1 - 8 6.8 16.0 6 7.2 3.8 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 Pkinase PF00069.25 KXZ42321.1 - 2.3e-61 207.5 0.0 3e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42321.1 - 1.1e-27 97.0 0.0 1.6e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ42321.1 - 0.00072 19.0 0.0 0.0013 18.1 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Cytochrom_B562 PF07361.11 KXZ42321.1 - 0.097 13.3 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b562 Voldacs PF03517.13 KXZ42324.1 - 8.8e-27 93.9 0.4 1.1e-25 90.4 0.0 2.2 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling PH_TFIIH PF08567.11 KXZ42324.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain GST_N_2 PF13409.6 KXZ42325.1 - 3.1e-19 69.0 0.0 6.4e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ42325.1 - 1.1e-10 41.4 0.3 2.8e-10 40.1 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXZ42325.1 - 1e-08 35.3 0.0 2.3e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXZ42325.1 - 5.2e-06 26.8 0.0 0.0025 18.2 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXZ42325.1 - 1.8e-05 24.8 0.0 6.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXZ42325.1 - 0.044 13.6 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HflK_N PF12221.8 KXZ42326.1 - 0.023 14.7 1.1 0.058 13.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Sporozoite_P67 PF05642.11 KXZ42326.1 - 9.8 4.1 9.8 10 4.1 9.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 KXZ42328.1 - 3.9e-60 203.4 0.0 4.4e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42328.1 - 7e-29 100.9 0.0 7.8e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXZ42328.1 - 0.0002 21.0 0.6 0.00027 20.6 0.6 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXZ42328.1 - 0.001 19.1 0.1 1.1 9.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXZ42328.1 - 0.0044 16.6 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KXZ42328.1 - 0.0052 15.6 0.0 0.037 12.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXZ42328.1 - 0.0067 15.8 0.3 0.015 14.7 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ42328.1 - 0.012 15.0 0.3 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 KXZ42328.1 - 0.025 14.2 0.3 1.3 8.6 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1679 PF07914.11 KXZ42328.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) TRP PF06011.12 KXZ42329.1 - 0.032 12.9 19.5 0.014 14.1 11.0 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel MSC PF09402.10 KXZ42329.1 - 2.6 7.4 4.6 5.9 6.2 4.6 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain LSM PF01423.22 KXZ42331.1 - 1.2e-16 60.1 0.5 1.9e-16 59.5 0.2 1.5 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 KXZ42331.1 - 0.032 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Hfq protein ABC1 PF03109.16 KXZ42332.1 - 1.5e-28 99.4 0.0 2.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 ABC1 family DUF765 PF05570.11 KXZ42332.1 - 0.21 11.8 2.6 0.7 10.1 2.6 1.9 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) APH PF01636.23 KXZ42332.1 - 2.4 8.0 9.1 0.47 10.3 0.4 3.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 KXZ42333.1 - 9.4e-20 70.5 0.1 1.1e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ42333.1 - 7.3e-08 32.5 0.1 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXZ42333.1 - 0.0038 17.1 0.2 0.8 9.6 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 KXZ42333.1 - 0.068 13.2 0.0 0.39 10.8 0.0 2.1 1 1 1 2 2 2 0 SLIDE Chlorophyllase2 PF12740.7 KXZ42334.1 - 6.9e-09 35.0 0.0 2.6e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXZ42334.1 - 0.022 14.0 0.1 1.9 7.7 0.3 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXZ42334.1 - 0.058 12.4 0.0 0.4 9.6 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase DUF1091 PF06477.13 KXZ42337.1 - 0.075 13.5 0.1 4.4 7.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1091) PyrI_C PF02748.15 KXZ42339.1 - 0.013 15.4 1.6 0.019 14.8 1.6 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FMP23 PF17315.2 KXZ42342.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Found in mitochondrial proteome Na_trans_assoc PF06512.13 KXZ42343.1 - 0.038 14.3 4.6 0.097 12.9 4.6 1.7 1 0 0 1 1 1 0 Sodium ion transport-associated SH3_6 PF12913.7 KXZ42343.1 - 0.49 10.0 1.8 0.54 9.9 0.3 1.9 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) BHD_2 PF10404.9 KXZ42343.1 - 1.1 10.3 4.6 4.3 8.3 4.6 2.0 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Presenilin PF01080.17 KXZ42343.1 - 3.3 6.4 4.5 4.9 5.8 4.5 1.2 1 0 0 1 1 1 0 Presenilin DctM PF06808.12 KXZ42344.1 - 0.075 11.8 4.1 0.055 12.3 2.8 1.3 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Ank_5 PF13857.6 KXZ42346.1 - 6.4e-21 74.2 0.6 8.4e-10 38.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42346.1 - 2.2e-19 67.5 2.2 0.0004 20.6 0.1 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 KXZ42346.1 - 1.2e-17 64.2 0.2 1.1e-09 38.7 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ42346.1 - 1.5e-17 63.1 10.2 3.2e-06 27.3 0.5 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ42346.1 - 8.8e-16 58.1 0.4 1.5e-05 25.5 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42347.1 - 0.016 15.7 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.6 KXZ42347.1 - 0.021 15.2 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) VHS PF00790.19 KXZ42349.1 - 0.048 13.5 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 VHS domain YyzF PF14116.6 KXZ42349.1 - 0.14 12.2 0.1 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 YyzF-like protein SPOB_a PF14689.6 KXZ42349.1 - 0.14 11.8 0.1 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Type2_restr_D3 PF16902.5 KXZ42350.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Ank_2 PF12796.7 KXZ42351.1 - 2.5e-66 220.3 11.2 6.3e-17 61.9 0.7 5.7 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42351.1 - 1.2e-50 169.3 0.4 1.9e-12 47.4 0.0 6.4 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42351.1 - 1.9e-49 164.0 11.3 2.3e-06 27.8 0.0 8.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KXZ42351.1 - 2.1e-47 158.6 7.7 1.3e-11 44.5 0.6 6.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42351.1 - 1e-45 148.4 0.9 0.0002 21.6 0.0 8.9 9 0 0 9 9 9 8 Ankyrin repeat DUF2384 PF09722.10 KXZ42351.1 - 0.001 19.1 0.2 5.7 7.1 0.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF2384) Big_10 PF17964.1 KXZ42351.1 - 0.027 14.5 2.8 3.3 7.6 0.5 2.9 1 1 1 3 3 3 0 Bacterial Ig domain DUF4988 PF16378.5 KXZ42351.1 - 0.039 13.6 1.7 3.3 7.3 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function gpW PF02831.15 KXZ42351.1 - 0.092 12.7 0.8 29 4.7 0.1 3.5 3 0 0 3 3 3 0 gpW Fer4_14 PF13394.6 KXZ42351.1 - 0.1 12.7 0.0 1.8 8.7 0.0 2.8 3 1 0 3 3 3 0 4Fe-4S single cluster domain DUF1843 PF08898.10 KXZ42351.1 - 0.29 11.7 12.4 12 6.5 0.4 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) OTU PF02338.19 KXZ42353.1 - 4.3e-07 30.5 0.0 6.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease zf-UBP PF02148.19 KXZ42353.1 - 0.03 14.7 0.3 0.054 13.8 0.3 1.4 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Siva PF05458.12 KXZ42353.1 - 6.7 6.4 9.7 26 4.4 6.9 2.2 1 1 0 2 2 2 0 Cd27 binding protein (Siva) CENP-T_C PF15511.6 KXZ42354.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ42354.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ42354.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ42354.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ42354.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ42354.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ42354.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated LRR_6 PF13516.6 KXZ42358.1 - 2.4e-17 61.4 3.9 0.13 12.3 0.0 9.9 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 KXZ42358.1 - 3.1e-07 30.6 0.3 0.041 14.3 0.0 5.1 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) WPP PF13943.6 KXZ42358.1 - 5.1e-06 26.8 0.3 5.1e-06 26.8 0.3 1.8 2 0 0 2 2 2 1 WPP domain LRR_1 PF00560.33 KXZ42358.1 - 0.00032 20.8 0.3 27 5.9 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KXZ42358.1 - 0.37 10.6 11.1 4.1 7.2 0.0 5.6 6 2 0 6 6 6 0 Leucine rich repeat Castor_Poll_mid PF06241.12 KXZ42359.1 - 1.2e-11 44.5 0.0 1.2e-06 28.4 0.0 2.8 3 0 0 3 3 3 2 Castor and Pollux, part of voltage-gated ion channel Sulfotransfer_3 PF13469.6 KXZ42359.1 - 0.032 14.6 2.4 0.46 10.8 0.0 2.6 2 0 0 2 2 2 0 Sulfotransferase family SNF2_N PF00176.23 KXZ42361.1 - 2.6e-08 33.0 0.0 3.8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C2HC_2 PF13913.6 KXZ42361.1 - 0.0039 17.1 0.5 0.0068 16.3 0.5 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KXZ42361.1 - 0.22 12.5 0.8 0.4 11.6 0.8 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXZ42361.1 - 0.23 12.0 0.6 0.44 11.1 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pyr_redox_3 PF13738.6 KXZ42362.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase cNMP_binding PF00027.29 KXZ42366.1 - 3.7e-24 84.6 0.0 1.3e-13 50.8 0.0 2.8 1 1 1 2 2 2 2 Cyclic nucleotide-binding domain Evr1_Alr PF04777.13 KXZ42367.1 - 1.4e-38 131.4 0.1 5.2e-25 87.8 0.0 2.1 2 0 0 2 2 2 2 Erv1 / Alr family SNAD4 PF18750.1 KXZ42367.1 - 1.7e-05 24.9 0.0 0.075 13.2 0.0 2.2 1 1 1 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 dCMP_cyt_deam_1 PF00383.23 KXZ42367.1 - 0.0055 16.6 0.0 3.7 7.5 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC4_like PF18774.1 KXZ42367.1 - 0.013 15.4 0.0 3 7.8 0.0 2.2 1 1 1 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 KXZ42367.1 - 0.023 14.9 0.0 4 7.8 0.0 2.3 1 1 1 2 2 2 0 APOBEC1 APOBEC2 PF18772.1 KXZ42367.1 - 0.028 14.5 0.1 6.5 6.8 0.0 2.1 1 1 1 2 2 2 0 APOBEC2 XOO_2897-deam PF14440.6 KXZ42367.1 - 0.035 14.2 0.2 0.53 10.4 0.0 2.2 1 1 1 2 2 2 0 Xanthomonas XOO_2897-like deaminase NAD1 PF18778.1 KXZ42367.1 - 0.08 13.0 0.0 7.8 6.6 0.0 2.1 1 1 1 2 2 2 0 Novel AID APOBEC clade 1 DUF2277 PF10041.9 KXZ42367.1 - 0.081 13.3 1.7 0.32 11.3 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) DUF1484 PF07363.11 KXZ42367.1 - 0.25 12.3 2.1 25 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) DNA_RNApol_7kD PF03604.13 KXZ42367.1 - 0.32 10.7 1.3 16 5.3 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF4205 PF13898.6 KXZ42368.1 - 0.082 11.8 0.4 0.11 11.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) Evr1_Alr PF04777.13 KXZ42369.1 - 4.3e-39 133.0 0.1 3.2e-25 88.5 0.0 2.1 2 0 0 2 2 2 2 Erv1 / Alr family SNAD4 PF18750.1 KXZ42369.1 - 8.3e-05 22.7 0.0 0.27 11.4 0.0 2.1 1 1 1 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 DUF4630 PF15443.6 KXZ42369.1 - 0.00047 20.4 0.7 1.3 9.2 0.0 2.8 1 1 1 3 3 3 2 Domain of unknown function (DUF4630) dCMP_cyt_deam_1 PF00383.23 KXZ42369.1 - 0.0032 17.3 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC4_like PF18774.1 KXZ42369.1 - 0.011 15.7 0.0 2.6 8.0 0.0 2.2 1 1 1 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase DUF2277 PF10041.9 KXZ42369.1 - 0.022 15.1 2.1 0.43 10.9 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) APOBEC1 PF18769.1 KXZ42369.1 - 0.027 14.7 0.0 4.3 7.7 0.0 2.3 1 1 1 2 2 2 0 APOBEC1 APOBEC2 PF18772.1 KXZ42369.1 - 0.052 13.6 0.1 4.6 7.3 0.0 2.1 1 1 1 2 2 2 0 APOBEC2 NAD1 PF18778.1 KXZ42369.1 - 0.12 12.4 0.0 6.5 6.8 0.0 2.1 1 1 0 2 2 2 0 Novel AID APOBEC clade 1 DUF1484 PF07363.11 KXZ42369.1 - 0.19 12.8 2.4 20 6.3 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1484) DNA_RNApol_7kD PF03604.13 KXZ42369.1 - 0.88 9.3 4.0 12 5.6 0.1 2.8 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF2722 PF10846.8 KXZ42370.1 - 0.00049 19.2 1.9 0.00062 18.8 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 KXZ42370.1 - 0.0013 18.8 5.3 0.0017 18.5 5.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXZ42370.1 - 0.0046 16.6 9.4 0.0064 16.1 9.4 1.2 1 0 0 1 1 1 1 Spt20 family Methyltransf_23 PF13489.6 KXZ42370.1 - 0.044 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SARAF PF06682.12 KXZ42370.1 - 0.053 13.2 3.4 0.15 11.7 3.4 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Suf PF05843.14 KXZ42370.1 - 0.12 12.3 2.5 0.19 11.7 2.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.6 KXZ42370.1 - 0.18 11.0 1.8 0.25 10.5 1.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2786 PF10979.8 KXZ42370.1 - 0.22 11.5 0.0 0.22 11.5 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2786) Med3 PF11593.8 KXZ42370.1 - 1.5 7.9 24.9 2.4 7.2 24.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PepSY_TM PF03929.16 KXZ42370.1 - 9.3 5.8 11.5 4.7 6.8 9.1 1.8 1 1 0 1 1 1 0 PepSY-associated TM region P_proprotein PF01483.20 KXZ42371.1 - 4.5e-07 29.8 0.0 3.9e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Proprotein convertase P-domain Nop14 PF04147.12 KXZ42372.1 - 0.0011 17.3 36.8 0.0011 17.3 36.8 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 KXZ42372.1 - 0.013 14.9 40.2 0.012 15.0 40.2 1.0 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 KXZ42372.1 - 0.04 12.4 28.1 0.044 12.2 28.1 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 KXZ42372.1 - 7.6 5.8 40.4 8.3 5.6 40.4 1.0 1 0 0 1 1 1 0 BUD22 Baculo_p74_N PF08404.10 KXZ42373.1 - 0.00032 19.9 0.0 0.75 8.8 0.0 2.3 2 0 0 2 2 2 2 Baculoviridae P74 N-terminal RNA12 PF10443.9 KXZ42373.1 - 0.41 9.3 0.8 19 3.8 0.1 2.1 2 0 0 2 2 2 0 RNA12 protein DUF2967 PF11179.8 KXZ42373.1 - 0.48 8.5 2.5 7.5 4.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Ank_4 PF13637.6 KXZ42375.1 - 0.00026 21.5 2.2 6.2 7.5 0.5 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42375.1 - 0.0049 17.4 0.1 5.6 7.6 0.0 3.5 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42375.1 - 0.3 11.8 3.9 1.2e+02 3.8 0.0 5.3 6 0 0 6 6 6 0 Ankyrin repeat Chloroa_b-bind PF00504.21 KXZ42377.1 - 0.00036 21.1 0.3 0.0006 20.4 0.3 1.5 1 1 0 1 1 1 1 Chlorophyll A-B binding protein OppC_N PF12911.7 KXZ42377.1 - 0.093 12.7 1.0 15 5.7 0.2 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C NIF PF03031.18 KXZ42379.1 - 0.031 14.1 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Caskin-Pro-rich PF16907.5 KXZ42379.1 - 1.9 9.1 12.0 0.094 13.3 1.5 2.9 3 0 0 3 3 3 0 Proline rich region of Caskin proteins PKS_DE PF18369.1 KXZ42381.1 - 0.22 12.1 0.5 0.22 12.1 0.5 1.6 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain O-FucT PF10250.9 KXZ42382.1 - 0.0022 17.8 0.0 0.0037 17.0 0.0 1.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ribosomal_L7Ae PF01248.26 KXZ42382.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Helitron_like_N PF14214.6 KXZ42384.1 - 1.3e-17 64.7 0.1 2.1e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus V4R PF02830.18 KXZ42384.1 - 0.14 12.2 0.4 0.29 11.2 0.4 1.5 1 0 0 1 1 1 0 V4R domain DUF5473 PF17567.2 KXZ42385.1 - 0.0088 16.3 0.7 0.023 15.0 0.7 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5473) Peptidase_C48 PF02902.19 KXZ42385.1 - 0.095 12.5 1.5 1.7 8.4 0.2 2.1 1 1 1 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain Retrotrans_gag PF03732.17 KXZ42387.1 - 2.2e-07 31.1 0.0 4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.26 KXZ42388.1 - 0.0032 17.7 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KXZ42388.1 - 0.032 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 KXZ42389.1 - 3.6e-21 75.7 0.0 5.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KXZ42389.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 KXZ42390.1 - 2.7e-07 31.1 0.0 3.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXZ42390.1 - 0.00018 22.0 0.1 0.00027 21.5 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KXZ42390.1 - 0.0041 16.9 0.0 0.0052 16.6 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KXZ42390.1 - 0.016 15.0 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease FAP PF07174.11 KXZ42391.1 - 3.7 6.9 21.9 4.6 6.6 21.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) LysM PF01476.20 KXZ42392.1 - 1.1e-06 28.5 0.0 3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 LysM domain CYSTM PF12734.7 KXZ42392.1 - 0.014 15.7 2.0 0.036 14.4 2.0 1.7 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Fer2_4 PF13510.6 KXZ42392.1 - 0.11 12.5 0.1 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_9 PF00759.19 KXZ42396.1 - 4.1e-61 207.7 1.4 5.1e-61 207.3 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KXZ42397.1 - 5.5e-50 171.0 2.0 6.3e-50 170.8 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GDPD PF03009.17 KXZ42399.1 - 1.5e-43 149.4 0.0 2.3e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RVT_1 PF00078.27 KXZ42400.1 - 4.4e-09 36.2 0.0 7.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 KXZ42400.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family YajC PF02699.15 KXZ42401.1 - 0.21 11.5 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit BTB PF00651.31 KXZ42402.1 - 0.0049 17.1 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ42403.1 - 0.0075 16.5 0.0 0.017 15.4 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KXZ42405.1 - 1.2e-06 28.7 0.0 0.00095 19.4 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain ABC2_membrane PF01061.24 KXZ42407.1 - 8e-07 28.7 9.3 2.9e-06 26.9 9.3 1.9 1 1 0 1 1 1 1 ABC-2 type transporter Ion_trans PF00520.31 KXZ42407.1 - 0.024 13.9 4.1 0.15 11.3 4.5 1.9 1 1 1 2 2 2 0 Ion transport protein TRP PF06011.12 KXZ42408.1 - 6.2e-08 31.8 14.5 7.3e-08 31.6 11.7 2.0 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel Chlam_PMP PF02415.17 KXZ42409.1 - 5.3e-06 26.6 76.1 0.25 11.9 2.5 11.7 11 2 0 11 11 11 9 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chlam_PMP PF02415.17 KXZ42410.1 - 0.027 14.9 21.4 2.2 8.9 6.3 4.5 3 2 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF716 PF04819.12 KXZ42411.1 - 0.34 10.5 4.8 5.8 6.6 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF716) RVT_1 PF00078.27 KXZ42413.1 - 1.5e-09 37.7 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KXZ42413.1 - 0.00084 19.6 0.0 0.0031 17.8 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KXZ42413.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Peptidase_M6 PF05547.11 KXZ42416.1 - 0.96 7.7 2.2 1.3 7.3 2.2 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 OATP PF03137.20 KXZ42417.1 - 0.0019 16.6 0.1 0.0022 16.4 0.1 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_5 PF12695.7 KXZ42418.1 - 0.071 12.9 0.0 14 5.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family BTAD PF03704.17 KXZ42418.1 - 0.085 13.3 0.1 13 6.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial transcriptional activator domain MFS_1 PF07690.16 KXZ42419.1 - 5.2e-12 45.4 14.5 5.2e-12 45.4 14.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXZ42419.1 - 1.1e-09 37.2 7.1 1.1e-07 30.6 0.9 2.4 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXZ42419.1 - 0.0003 19.8 5.7 0.00037 19.5 5.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1350 PF07082.11 KXZ42420.1 - 8.4e-43 146.4 0.0 1.1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1350) Hydrolase_4 PF12146.8 KXZ42420.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ42420.1 - 4.4 7.9 16.1 25 5.4 14.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3007 PF11460.8 KXZ42421.1 - 2.3e-33 114.3 2.7 3e-33 114.0 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) Wzy_C PF04932.15 KXZ42421.1 - 0.041 13.5 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase TRP PF06011.12 KXZ42423.1 - 0.00026 19.9 16.3 0.00026 19.9 16.3 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel JAMP PF05571.12 KXZ42423.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 JNK1/MAPK8-associated membrane protein Laminin_EGF PF00053.24 KXZ42423.1 - 0.45 10.7 2.0 0.86 9.8 2.0 1.4 1 0 0 1 1 1 0 Laminin EGF domain TRP PF06011.12 KXZ42425.1 - 3.8e-05 22.6 15.8 3.8e-05 22.6 15.8 2.0 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel MAP17 PF15807.5 KXZ42425.1 - 0.1 12.8 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Laminin_EGF PF00053.24 KXZ42425.1 - 0.43 10.8 2.4 0.84 9.8 2.4 1.4 1 0 0 1 1 1 0 Laminin EGF domain Ank_2 PF12796.7 KXZ42426.1 - 1.1e-48 163.8 8.6 4.5e-18 65.6 0.3 4.9 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42426.1 - 6.1e-44 147.9 0.1 1.1e-11 45.0 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42426.1 - 3.7e-43 144.1 11.1 4.5e-06 26.9 0.1 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KXZ42426.1 - 2.5e-41 139.2 13.0 3.7e-07 30.3 0.1 8.2 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42426.1 - 5.2e-37 121.7 2.7 0.00019 21.6 0.0 8.9 9 0 0 9 9 9 8 Ankyrin repeat SR-25 PF10500.9 KXZ42426.1 - 0.047 13.3 11.4 0.08 12.5 11.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2642 PF10842.8 KXZ42426.1 - 0.2 11.5 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Tox-SHH PF15652.6 KXZ42426.1 - 0.29 12.1 2.1 1 10.3 2.1 2.0 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature DUF4820 PF16091.5 KXZ42426.1 - 2.8 7.2 7.3 4.8 6.5 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ank_2 PF12796.7 KXZ42427.1 - 1.9e-50 169.3 0.2 1.5e-16 60.7 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ42427.1 - 7.4e-47 155.8 0.3 5.8e-08 32.8 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KXZ42427.1 - 1.9e-40 136.7 0.0 1.8e-13 50.7 0.0 5.4 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ42427.1 - 1.3e-39 133.7 1.1 1.4e-11 44.3 0.1 7.0 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42427.1 - 9.7e-38 123.9 0.0 8.1e-06 25.8 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat DUF4988 PF16378.5 KXZ42427.1 - 0.025 14.3 0.2 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function PEGA PF08308.11 KXZ42427.1 - 0.2 11.6 0.1 17 5.4 0.0 3.4 5 0 0 5 5 5 0 PEGA domain Asp_protease_2 PF13650.6 KXZ42429.1 - 0.027 15.1 0.0 0.14 12.8 0.0 2.3 1 0 0 1 1 1 0 Aspartyl protease APC_rep PF18797.1 KXZ42429.1 - 0.032 15.2 0.8 17 6.4 0.1 3.6 2 0 0 2 2 2 0 Adenomatous polyposis coli (APC) repeat PXA PF02194.15 KXZ42429.1 - 0.27 11.2 0.4 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 PXA domain baeRF_family10 PF18854.1 KXZ42429.1 - 3.7 7.8 8.2 14 6.0 1.1 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 T5orf172 PF10544.9 KXZ42431.1 - 2.9e-06 27.7 0.4 6.2e-06 26.7 0.2 1.6 1 1 1 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KXZ42431.1 - 0.00011 22.8 0.0 0.00016 22.3 0.0 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 D5_N PF08706.11 KXZ42432.1 - 2.6e-16 60.2 0.0 4.7e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 D5 N terminal like Prim-Pol PF09250.11 KXZ42432.1 - 4.9e-07 30.3 0.0 1.5e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Bifunctional DNA primase/polymerase, N-terminal AAA_29 PF13555.6 KXZ42432.1 - 0.11 12.3 0.2 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain tRNA-synt_His PF13393.6 KXZ42434.1 - 0.023 14.0 0.1 0.027 13.8 0.1 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Chromo PF00385.24 KXZ42437.1 - 3.1e-09 36.6 0.1 4.4e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4922 PF16269.5 KXZ42437.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) DUF3878 PF12994.7 KXZ42438.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) Pkinase_fungal PF17667.1 KXZ42439.1 - 0.013 14.3 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF496 PF04363.12 KXZ42439.1 - 0.056 13.5 0.0 0.095 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF496) DUF2718 PF10918.8 KXZ42441.1 - 0.015 15.8 0.7 2.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) Yippee-Mis18 PF03226.14 KXZ42441.1 - 0.021 15.1 1.6 0.057 13.6 0.4 2.2 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cornifin PF02389.15 KXZ42443.1 - 0.0047 17.1 9.4 0.0078 16.4 9.4 1.3 1 0 0 1 1 1 1 Cornifin (SPRR) family Guanylate_kin PF00625.21 KXZ42445.1 - 9.3e-36 123.2 0.0 1.2e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KXZ42445.1 - 0.0017 18.9 0.0 0.024 15.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ42445.1 - 0.005 17.2 0.1 0.016 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KXZ42445.1 - 0.026 13.8 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 KXZ42445.1 - 0.042 14.1 0.1 0.24 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXZ42445.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase BTB PF00651.31 KXZ42446.1 - 1.9e-15 57.1 0.0 3.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ42447.1 - 4.9e-14 52.5 0.0 9.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PBP1_TM PF14812.6 KXZ42448.1 - 0.0085 16.4 18.3 0.012 16.0 18.3 1.2 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 KXZ42448.1 - 0.02 14.6 17.1 0.025 14.3 17.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1754 PF08555.10 KXZ42448.1 - 0.031 15.1 11.5 0.039 14.7 11.5 1.1 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FYDLN_acid PF09538.10 KXZ42448.1 - 0.032 14.9 15.4 0.043 14.5 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TFIIF_alpha PF05793.12 KXZ42448.1 - 0.14 10.7 17.9 0.17 10.4 17.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.14 KXZ42448.1 - 0.14 11.9 10.1 0.17 11.7 10.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 KXZ42448.1 - 0.18 9.9 13.1 0.19 9.9 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 KXZ42448.1 - 0.33 10.3 5.0 0.38 10.1 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PPL5 PF18168.1 KXZ42448.1 - 0.5 9.6 6.6 0.55 9.5 6.6 1.0 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 KXZ42448.1 - 0.52 8.5 13.9 0.57 8.4 13.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 KXZ42448.1 - 0.55 8.2 6.9 0.6 8.1 6.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPP4R2 PF09184.11 KXZ42448.1 - 0.63 9.6 13.0 0.66 9.5 13.0 1.1 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 KXZ42448.1 - 0.71 9.9 10.4 1 9.4 10.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NPR3 PF03666.13 KXZ42448.1 - 0.98 8.1 8.1 1.1 8.0 8.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NOA36 PF06524.12 KXZ42448.1 - 1.4 8.2 18.4 1.6 8.0 18.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3824 PF12868.7 KXZ42448.1 - 1.4 9.6 9.7 2.7 8.7 9.8 1.5 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) ANAPC15 PF15243.6 KXZ42448.1 - 1.5 9.3 16.7 2.1 8.8 16.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF913 PF06025.12 KXZ42448.1 - 2 7.3 4.2 2 7.3 4.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Afi1 PF07792.12 KXZ42448.1 - 2.1 8.8 10.7 2.6 8.5 10.7 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RRN3 PF05327.11 KXZ42448.1 - 2.7 6.5 12.2 2.8 6.4 12.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 KXZ42448.1 - 3.2 6.8 12.5 3.5 6.7 12.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Zip PF02535.22 KXZ42448.1 - 4.8 6.3 4.3 5 6.2 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 KXZ42448.1 - 5.5 5.0 20.3 6.4 4.7 20.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi FancD2 PF14631.6 KXZ42448.1 - 5.5 4.2 5.8 6 4.1 5.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease BTB PF00651.31 KXZ42449.1 - 2.9e-14 53.2 0.0 6.9e-14 52.0 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KXZ42452.1 - 1.4e-15 57.5 0.0 2.8e-15 56.5 0.0 1.4 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KXZ42454.1 - 5.8e-15 55.5 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ42455.1 - 2.7e-15 56.5 0.0 4.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CesT PF05932.13 KXZ42455.1 - 0.14 12.3 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family DUF1308 PF07000.11 KXZ42456.1 - 1.9e-21 76.7 0.0 3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Peptidase_M14 PF00246.24 KXZ42457.1 - 1.8e-23 83.8 0.0 2.3e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Med3 PF11593.8 KXZ42457.1 - 0.27 10.4 6.2 0.36 10.0 6.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RT_RNaseH PF17917.1 KXZ42459.1 - 7.6e-34 116.2 0.0 9.2e-34 115.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KXZ42459.1 - 1.7e-32 111.4 0.0 2.3e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 KXZ42460.1 - 0.026 14.6 1.5 0.042 13.9 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle KH_1 PF00013.29 KXZ42461.1 - 8.9e-25 86.3 2.6 7.9e-13 48.0 0.2 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KXZ42461.1 - 0.00026 20.8 1.1 0.071 12.9 0.1 2.3 2 0 0 2 2 2 2 KH domain DUF1798 PF08807.10 KXZ42462.1 - 0.039 14.1 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Ribosom_S12_S23 PF00164.25 KXZ42463.1 - 1.9e-35 120.9 0.7 2.3e-35 120.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KXZ42463.1 - 0.00035 21.2 0.0 0.00061 20.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S12 Ras PF00071.22 KXZ42464.1 - 1.3e-41 142.0 0.0 1.4e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ42464.1 - 1.6e-24 86.4 0.0 2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ42464.1 - 4.2e-08 32.8 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXZ42464.1 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXZ42464.1 - 0.0023 17.3 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXZ42464.1 - 0.021 14.7 0.0 4 7.3 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 KXZ42464.1 - 0.09 12.9 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ42464.1 - 0.15 12.4 0.0 0.49 10.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain TPT PF03151.16 KXZ42465.1 - 2.4e-09 37.0 5.2 3.6e-09 36.4 5.2 1.2 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ42465.1 - 0.074 13.2 17.6 0.024 14.8 2.4 2.5 2 1 0 2 2 2 0 EamA-like transporter family p450 PF00067.22 KXZ42466.1 - 3.8e-21 75.4 1.7 2.2e-09 36.6 0.1 3.7 3 1 1 4 4 4 3 Cytochrome P450 TPR_2 PF07719.17 KXZ42467.1 - 1.7e-10 40.2 12.8 0.00016 21.5 1.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ42467.1 - 1.3e-09 37.5 9.4 0.0002 21.1 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ42467.1 - 4.1e-07 29.6 1.3 0.0021 17.7 0.8 2.5 2 0 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.6 KXZ42467.1 - 0.0022 18.1 0.3 0.14 12.3 0.1 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KXZ42467.1 - 0.01 16.4 16.0 0.043 14.3 4.7 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ42467.1 - 0.012 16.3 1.3 0.012 16.3 1.3 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ42467.1 - 0.067 13.5 8.1 1 9.7 0.8 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42467.1 - 0.34 11.8 17.8 1.7 9.7 2.8 4.2 2 1 1 4 4 4 0 Tetratricopeptide repeat RNA_pol_Rpb2_6 PF00562.28 KXZ42468.1 - 4.1e-111 371.8 0.1 6.9e-111 371.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXZ42468.1 - 7.4e-54 182.3 0.1 1.1e-53 181.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KXZ42468.1 - 8.8e-47 159.2 0.0 3.3e-46 157.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXZ42468.1 - 1.2e-31 109.0 0.2 1.2e-30 105.7 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KXZ42468.1 - 1.1e-24 86.3 0.0 2.4e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KXZ42468.1 - 9.2e-20 70.7 0.0 3e-19 69.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KXZ42468.1 - 2.2e-19 69.8 0.2 9.9e-19 67.7 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Spond_N PF06468.13 KXZ42469.1 - 0.3 11.2 1.6 0.41 10.8 1.6 1.1 1 0 0 1 1 1 0 Spondin_N UBM PF14377.6 KXZ42469.1 - 1.2 8.7 7.8 2 8.0 4.9 2.6 1 1 1 2 2 2 0 Ubiquitin binding region RPA_interact_M PF14767.6 KXZ42469.1 - 3.7 8.2 10.1 37 5.0 7.6 2.7 1 1 1 2 2 2 0 Replication protein A interacting middle DUF4226 PF10774.9 KXZ42470.1 - 0.04 14.2 0.8 0.061 13.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Gln-synt_N PF03951.19 KXZ42472.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 KXZ42474.1 - 4.3e-08 32.5 58.6 4e-05 22.7 31.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ42474.1 - 9.8e-05 21.4 17.1 0.00072 18.5 3.1 2.5 1 1 0 2 2 2 2 Sugar (and other) transporter UNC-93 PF05978.16 KXZ42474.1 - 0.0067 16.2 2.3 0.017 14.8 2.3 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Fungus-induced PF10917.8 KXZ42474.1 - 9.8 6.6 7.9 0.89 9.9 1.5 2.7 3 0 0 3 3 3 0 Fungus-induced protein AAA_18 PF13238.6 KXZ42475.1 - 3.5e-15 56.7 0.1 3.9e-15 56.6 0.1 1.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXZ42475.1 - 2.1e-08 34.6 0.0 2.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXZ42475.1 - 7.9e-06 26.3 0.0 7.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXZ42475.1 - 1.6e-05 25.2 0.0 1.7e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KXZ42475.1 - 8.3e-05 22.6 0.0 8.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 NTPase ADK PF00406.22 KXZ42475.1 - 0.00023 21.3 0.0 0.00033 20.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.6 KXZ42475.1 - 0.00035 20.8 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXZ42475.1 - 0.00075 19.3 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ42475.1 - 0.0015 18.8 0.0 0.0015 18.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ42475.1 - 0.0016 18.9 0.0 0.0016 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KXZ42475.1 - 0.0023 17.0 0.1 0.0027 16.8 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KXZ42475.1 - 0.0038 17.5 0.1 0.0051 17.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXZ42475.1 - 0.0042 16.4 0.0 0.0069 15.7 0.0 1.4 2 0 0 2 2 1 1 Zeta toxin Rad17 PF03215.15 KXZ42475.1 - 0.0081 16.1 0.0 0.0082 16.1 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 KXZ42475.1 - 0.012 15.3 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase SKI PF01202.22 KXZ42475.1 - 0.018 15.1 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate kinase ATPase PF06745.13 KXZ42475.1 - 0.019 14.3 0.1 0.026 13.8 0.1 1.1 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 KXZ42475.1 - 0.026 14.3 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXZ42475.1 - 0.028 14.4 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KXZ42475.1 - 0.045 13.1 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.10 KXZ42475.1 - 0.052 13.0 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 KXZ42475.1 - 0.06 13.1 0.6 0.079 12.7 0.5 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXZ42475.1 - 0.073 13.5 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KXZ42475.1 - 0.094 11.9 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 KXZ42475.1 - 0.096 12.8 0.0 0.098 12.8 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_3 PF07726.11 KXZ42475.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.4 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXZ42475.1 - 0.12 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region dNK PF01712.19 KXZ42475.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_11 PF13086.6 KXZ42475.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ42475.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.3 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 KXZ42475.1 - 0.15 11.0 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 KXZ42475.1 - 0.16 10.8 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 KXZ42475.1 - 0.17 11.6 0.4 0.3 10.9 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 KXZ42475.1 - 0.18 11.8 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF853 PF05872.12 KXZ42475.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Sigma54_activat PF00158.26 KXZ42475.1 - 0.19 11.4 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXZ42475.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Hydin_ADK PF17213.3 KXZ42475.1 - 0.23 11.7 0.0 0.27 11.5 0.0 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TIP49 PF06068.13 KXZ42475.1 - 0.25 10.5 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain 6PF2K PF01591.18 KXZ42475.1 - 0.27 10.5 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NmrA PF05368.13 KXZ42476.1 - 0.17 11.4 3.5 0.39 10.2 3.5 1.6 1 0 0 1 1 1 0 NmrA-like family Aminotran_4 PF01063.19 KXZ42477.1 - 9.1e-23 81.3 0.0 3e-19 69.8 0.0 2.2 1 1 1 2 2 2 2 Amino-transferase class IV DUF4022 PF13214.6 KXZ42477.1 - 0.18 12.1 0.3 0.41 10.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) DUF3336 PF11815.8 KXZ42481.1 - 4.5e-24 84.7 0.1 7.5e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXZ42481.1 - 1.2e-11 45.2 3.5 1e-05 25.8 2.0 2.6 1 1 1 2 2 2 2 Patatin-like phospholipase AAA_26 PF13500.6 KXZ42483.1 - 0.0029 17.5 0.0 0.0032 17.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain PTA_PTB PF01515.19 KXZ42484.1 - 3.5e-29 102.2 0.2 7.1e-29 101.1 0.3 1.4 2 0 0 2 2 2 1 Phosphate acetyl/butaryl transferase DRTGG PF07085.12 KXZ42484.1 - 8.5e-07 28.7 0.0 2.9e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 DRTGG domain Glyco_transf_90 PF05686.12 KXZ42486.1 - 3.1e-17 62.6 0.0 3.7e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXZ42486.1 - 0.0012 19.2 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 CDC50 PF03381.15 KXZ42488.1 - 0.18 11.3 0.3 0.21 11.1 0.3 1.1 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Pex2_Pex12 PF04757.14 KXZ42489.1 - 6e-12 45.6 2.4 2.1e-05 24.3 2.8 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 KXZ42489.1 - 0.00046 20.0 4.2 0.0013 18.5 4.1 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ42489.1 - 0.0014 18.9 2.7 0.0023 18.2 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXZ42489.1 - 0.0014 18.4 2.2 0.0023 17.8 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ42489.1 - 0.015 15.3 4.4 0.026 14.5 4.4 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ42489.1 - 0.02 14.8 1.5 0.07 13.1 0.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KXZ42489.1 - 0.1 12.5 4.3 0.36 10.7 4.2 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXZ42489.1 - 0.17 11.7 6.8 0.76 9.7 7.4 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prim_Zn_Ribbon PF08273.12 KXZ42489.1 - 0.22 11.8 2.8 1.7 9.0 0.6 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-C3HC4_4 PF15227.6 KXZ42489.1 - 0.5 10.6 3.5 1 9.6 3.5 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1180 PF06679.12 KXZ42489.1 - 0.98 9.8 5.6 1.5 9.2 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF456 PF04306.13 KXZ42490.1 - 0.00015 22.1 1.8 0.00015 22.1 1.8 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF456) PAN_4 PF14295.6 KXZ42490.1 - 0.00066 19.5 2.8 0.0016 18.3 2.8 1.6 1 0 0 1 1 1 1 PAN domain Plasmodium_HRP PF05403.11 KXZ42490.1 - 5.2 6.8 11.0 0.021 14.7 1.4 1.8 2 0 0 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) S1 PF00575.23 KXZ42492.1 - 5.2e-14 52.3 0.4 2.4e-10 40.6 0.1 3.2 3 0 0 3 3 3 2 S1 RNA binding domain Cu_amine_oxid PF01179.20 KXZ42493.1 - 7.8e-42 143.6 2.7 5.1e-39 134.4 0.6 2.0 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Nucleotid_trans PF03407.16 KXZ42494.1 - 1.9e-07 31.3 0.0 3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 KXZ42495.1 - 6.6e-27 94.9 0.0 9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 KXZ42496.1 - 1.2e-29 103.9 0.1 1.6e-29 103.4 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PSD4 PF07631.11 KXZ42496.1 - 0.018 15.6 0.1 5 7.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) Nucleotid_trans PF03407.16 KXZ42497.1 - 1.2e-28 100.6 0.4 1.7e-28 100.0 0.4 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase FMN_bind_2 PF04299.12 KXZ42497.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative FMN-binding domain NAD_binding_1 PF00175.21 KXZ42498.1 - 2.5e-09 37.7 0.0 3.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXZ42498.1 - 0.19 11.8 0.5 7.3 6.7 0.0 2.2 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Abhydrolase_1 PF00561.20 KXZ42499.1 - 2.8e-26 92.7 0.1 1.8e-18 67.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ42499.1 - 4.7e-17 62.1 0.0 1.8e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ42499.1 - 2.1e-16 61.2 6.2 4.3e-16 60.2 6.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KXZ42499.1 - 1.5e-06 28.0 0.1 1.3e-05 24.9 0.0 2.2 2 1 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KXZ42499.1 - 1.3e-05 25.2 0.1 0.00066 19.6 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXZ42499.1 - 2.2e-05 24.4 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 KXZ42499.1 - 3.4e-05 23.6 1.0 6.7e-05 22.6 0.2 1.8 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 KXZ42499.1 - 0.00098 17.9 0.0 0.002 16.9 0.0 1.4 1 0 0 1 1 1 1 Ndr family UPF0227 PF05728.12 KXZ42499.1 - 0.002 18.1 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 KXZ42499.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KXZ42499.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 KXZ42499.1 - 0.025 14.1 0.0 0.44 10.0 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KXZ42499.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 KXZ42499.1 - 0.15 12.1 0.9 1.4 9.0 0.5 2.4 2 1 0 2 2 2 0 Thioesterase domain DUF2974 PF11187.8 KXZ42499.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SNARE_assoc PF09335.11 KXZ42500.1 - 1.7e-26 93.1 11.0 1.7e-26 93.1 11.0 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Lipase_GDSL_2 PF13472.6 KXZ42501.1 - 2.9e-08 34.3 0.0 5.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SAND PF01342.21 KXZ42502.1 - 0.0013 18.4 0.1 0.38 10.5 0.1 2.8 2 1 0 2 2 2 2 SAND domain AAA_30 PF13604.6 KXZ42505.1 - 4e-09 36.5 0.7 9.8e-09 35.2 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXZ42505.1 - 5.3e-08 33.3 0.0 2e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 KXZ42505.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_28 PF13521.6 KXZ42505.1 - 0.0079 16.5 0.9 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXZ42505.1 - 0.017 15.5 0.0 0.068 13.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Peptidase_C48 PF02902.19 KXZ42506.1 - 1.5e-07 31.5 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SSTK-IP PF15836.5 KXZ42508.1 - 0.074 13.2 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Alpha_TIF PF02232.15 KXZ42509.1 - 0.17 10.9 0.6 0.27 10.3 0.6 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Prp19 PF08606.11 KXZ42512.1 - 0.27 11.3 0.2 0.47 10.5 0.2 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like Cellulase PF00150.18 KXZ42513.1 - 3.2e-12 46.5 0.1 4.7e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KXZ42513.1 - 0.00041 19.8 0.1 0.00082 18.8 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase DUF218 PF02698.17 KXZ42515.1 - 6.9e-14 52.0 0.0 8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain ANAPC4_WD40 PF12894.7 KXZ42516.1 - 6.6e-07 29.5 0.3 0.18 12.1 0.0 5.2 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ42516.1 - 1.3e-06 29.0 10.5 5 8.2 0.0 7.6 9 0 0 9 9 9 3 WD domain, G-beta repeat PQQ_2 PF13360.6 KXZ42516.1 - 0.046 13.3 6.3 0.76 9.3 1.5 3.2 2 1 1 3 3 3 0 PQQ-like domain LELP1 PF15042.6 KXZ42516.1 - 7.6 7.0 15.5 0.23 11.8 4.0 2.5 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Cellulase PF00150.18 KXZ42518.1 - 5.2e-12 45.8 0.0 7.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KXZ42518.1 - 0.0011 18.4 0.1 0.0024 17.3 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase RPOL_N PF14700.6 KXZ42519.1 - 0.053 12.9 4.4 0.061 12.7 4.4 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal SHIPPO-rpt PF07004.12 KXZ42521.1 - 4e-13 49.6 66.5 0.013 16.4 0.2 11.3 12 0 0 12 12 12 9 Sperm-tail PG-rich repeat TPR_10 PF13374.6 KXZ42524.1 - 8.9e-08 31.8 0.9 8.9e-08 31.8 0.9 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Ank PF00023.30 KXZ42524.1 - 1.1e-07 32.0 0.5 1.1e-06 28.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXZ42524.1 - 2.4e-06 28.0 0.0 5.9e-06 26.8 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) TPR_12 PF13424.6 KXZ42524.1 - 2.6e-06 27.6 2.7 5.3e-06 26.6 2.7 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Ank_3 PF13606.6 KXZ42524.1 - 4.5e-06 26.6 0.0 1.7e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 KXZ42524.1 - 5.3e-06 26.6 0.1 1.3e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ42524.1 - 0.0013 19.3 0.0 0.0041 17.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) TPR_8 PF13181.6 KXZ42524.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ42524.1 - 0.066 13.4 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42524.1 - 0.18 12.7 0.2 0.18 12.7 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Presenilin PF01080.17 KXZ42525.1 - 2.4 6.9 11.2 2.7 6.7 11.2 1.0 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 KXZ42525.1 - 4.1 7.8 6.4 6.8 7.1 6.4 1.4 1 1 0 1 1 1 0 RNA polymerase III RPC4 PAN_4 PF14295.6 KXZ42526.1 - 1.5e-05 24.8 4.6 0.0089 15.9 1.5 2.9 2 1 0 2 2 2 2 PAN domain PAN_1 PF00024.26 KXZ42526.1 - 0.00038 20.4 8.0 0.00041 20.3 0.2 2.6 3 0 0 3 3 3 2 PAN domain PDEase_I PF00233.19 KXZ42527.1 - 1.2e-55 188.8 0.0 1.7e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KXZ42527.1 - 0.00053 20.2 3.6 0.00082 19.6 1.3 2.3 2 1 0 2 2 2 1 HD domain Mito_carr PF00153.27 KXZ42529.1 - 5.1e-69 228.3 0.2 1.8e-24 85.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KXZ42529.1 - 0.022 15.1 1.4 0.4 11.1 0.5 2.4 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Microvir_H PF04687.12 KXZ42530.1 - 0.012 15.0 0.9 0.013 14.9 0.9 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Phage_integrase PF00589.22 KXZ42531.1 - 0.0032 17.3 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 KXZ42533.1 - 0.025 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3670 PF12419.8 KXZ42534.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 SNF2 Helicase protein Microvir_H PF04687.12 KXZ42536.1 - 0.0048 16.3 2.6 0.0055 16.1 2.6 1.1 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) Sds3 PF08598.11 KXZ42536.1 - 0.25 11.3 5.8 0.3 11.1 5.8 1.0 1 0 0 1 1 1 0 Sds3-like ATG16 PF08614.11 KXZ42537.1 - 6.1e-06 26.6 15.0 6.1e-06 26.6 15.0 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 KXZ42537.1 - 0.01 13.8 0.7 0.013 13.5 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Miff PF05644.11 KXZ42537.1 - 0.045 13.4 4.9 0.07 12.7 4.8 1.3 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff GAS PF13851.6 KXZ42537.1 - 0.047 13.1 9.1 0.24 10.7 3.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 KXZ42537.1 - 0.062 12.8 7.6 0.058 12.9 5.3 1.7 1 1 1 2 2 2 0 Leucine zipper Cep57_MT_bd PF06657.13 KXZ42537.1 - 0.12 12.8 9.5 0.28 11.6 1.7 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 KXZ42537.1 - 0.13 12.9 6.2 0.47 11.1 0.5 2.7 1 1 1 2 2 2 0 Initiation control protein YabA NYD-SP28_assoc PF14775.6 KXZ42537.1 - 0.24 11.6 3.8 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain Cnn_1N PF07989.11 KXZ42537.1 - 1.1 9.5 5.0 4.1 7.6 1.4 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 KXZ42537.1 - 2.1 8.4 9.1 0.45 10.5 2.2 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 KXZ42537.1 - 4.3 7.6 12.6 8.1 6.7 6.7 2.9 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 KXZ42537.1 - 5.6 7.3 9.1 2.2 8.6 0.2 3.6 3 1 0 3 3 3 0 Homeobox associated leucine zipper Spc7 PF08317.11 KXZ42537.1 - 6 5.6 13.1 6.4 5.5 11.7 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Ax_dynein_light PF10211.9 KXZ42537.1 - 8.6 6.3 8.8 6.3 6.7 1.9 2.5 1 1 2 3 3 3 0 Axonemal dynein light chain Response_reg PF00072.24 KXZ42538.1 - 2.8e-24 85.4 0.0 5.5e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Myb_DNA-binding PF00249.31 KXZ42538.1 - 6e-06 26.3 0.0 9.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain GATA PF00320.27 KXZ42539.1 - 1.9e-14 53.0 5.0 3.8e-14 52.0 5.0 1.5 1 0 0 1 1 1 1 GATA zinc finger UCR_TM PF02921.14 KXZ42539.1 - 0.096 13.2 0.6 8.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region ADK_lid PF05191.14 KXZ42539.1 - 0.69 9.9 5.0 17 5.5 5.0 2.4 1 1 0 1 1 1 0 Adenylate kinase, active site lid Maf PF02545.14 KXZ42540.1 - 4.7e-35 120.9 0.0 5.5e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein PA28_beta PF02252.18 KXZ42542.1 - 0.015 15.0 1.8 1.5 8.5 0.1 3.0 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit PspB PF06667.12 KXZ42542.1 - 0.025 14.6 11.0 52 4.0 0.0 8.0 7 0 0 7 7 7 0 Phage shock protein B Fib_alpha PF08702.10 KXZ42542.1 - 1.5 9.0 30.4 10 6.3 0.2 8.1 8 0 0 8 8 8 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KXZ42542.1 - 6.9 6.7 58.8 0.054 13.5 0.7 11.8 12 2 2 14 14 14 0 Protein of unknown function (DUF1664) SRCR PF00530.18 KXZ42543.1 - 7.7e-16 58.4 4.1 2.1e-15 57.0 4.1 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain TRP PF06011.12 KXZ42543.1 - 2e-05 23.5 9.2 2e-05 23.5 9.2 2.2 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel MSC PF09402.10 KXZ42543.1 - 0.0058 16.1 2.6 0.013 15.0 2.6 1.5 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain JAMP PF05571.12 KXZ42543.1 - 0.017 14.8 0.2 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Peptidase_S8 PF00082.22 KXZ42544.1 - 2.3e-32 112.4 0.0 3.7e-20 72.4 0.0 2.7 1 1 1 2 2 2 2 Subtilase family UFC1 PF08694.11 KXZ42546.1 - 6e-83 276.1 0.3 6.9e-83 275.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 KXZ42546.1 - 0.0003 20.4 0.2 0.00084 19.0 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXZ42546.1 - 0.0018 18.5 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Aminotran_5 PF00266.19 KXZ42547.1 - 1.4e-21 76.9 0.0 7.1e-18 64.7 0.0 3.2 2 1 1 3 3 3 3 Aminotransferase class-V Thioredoxin PF00085.20 KXZ42547.1 - 3.7e-14 52.6 0.0 6.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXZ42547.1 - 0.00041 20.6 0.0 0.00088 19.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like zf_PR_Knuckle PF18445.1 KXZ42547.1 - 0.023 14.5 0.3 0.049 13.4 0.3 1.4 1 0 0 1 1 1 0 PR zinc knuckle motif Thioredoxin_2 PF13098.6 KXZ42547.1 - 0.24 11.9 0.6 1.3 9.5 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin-like domain tRNA-synt_His PF13393.6 KXZ42548.1 - 5.9e-52 176.9 3.3 2.1e-51 175.0 0.0 2.4 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 KXZ42548.1 - 5.4e-30 104.5 10.5 5.4e-30 104.5 10.5 2.4 2 1 1 3 3 3 1 Aromatic amino acid lyase HGTP_anticodon PF03129.20 KXZ42548.1 - 1e-08 35.2 0.0 2.6e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KXZ42548.1 - 7.5e-07 28.9 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 KXZ42548.1 - 0.0067 16.4 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KXZ42548.1 - 0.0088 15.2 0.0 0.042 12.9 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KXZ42548.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Thioredoxin PF00085.20 KXZ42548.1 - 0.18 11.8 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin TPR_12 PF13424.6 KXZ42549.1 - 0.00089 19.5 0.5 0.00089 19.5 0.5 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ42549.1 - 0.061 13.2 0.3 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.20 KXZ42550.1 - 3.5e-23 81.5 0.0 4.2e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ42550.1 - 1.8e-09 38.0 0.0 5.8e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KXZ42550.1 - 1.7e-06 28.1 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KXZ42550.1 - 3.9e-06 27.1 0.1 0.00016 21.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 KXZ42550.1 - 7.9e-06 25.4 0.0 8.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXZ42550.1 - 3.7e-05 23.6 0.0 4.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ42550.1 - 9.4e-05 22.2 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_6 PF13848.6 KXZ42550.1 - 0.00052 20.0 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KXZ42550.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredox_DsbH PF03190.15 KXZ42550.1 - 0.03 14.3 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF836 PF05768.14 KXZ42550.1 - 0.036 14.5 0.0 0.079 13.4 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DIM1 PF02966.16 KXZ42550.1 - 0.046 13.5 0.0 0.061 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 NAD_binding_1 PF00175.21 KXZ42550.1 - 0.094 13.4 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain KaiB PF07689.12 KXZ42550.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 KaiB domain DSBA PF01323.20 KXZ42550.1 - 0.11 12.3 0.0 2.2 8.0 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain LSM PF01423.22 KXZ42551.1 - 2.9e-14 52.5 0.0 3.8e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXZ42551.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KXZ42551.1 - 0.0011 19.0 0.2 0.0012 18.9 0.2 1.3 1 1 0 1 1 1 1 Scd6-like Sm domain Ten1_2 PF15490.6 KXZ42551.1 - 0.14 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit SET PF00856.28 KXZ42552.1 - 2.5e-09 37.7 0.0 4.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 SET domain TPR_1 PF00515.28 KXZ42552.1 - 3.9e-08 32.8 8.9 0.00048 19.8 0.7 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ42552.1 - 4.4e-05 23.4 0.3 0.51 10.7 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ42552.1 - 0.00015 21.6 13.0 0.0077 16.3 2.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ42552.1 - 0.00092 18.9 2.6 0.0032 17.1 0.6 2.7 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 KXZ42552.1 - 0.0044 17.6 4.2 0.0044 17.6 4.2 5.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ42552.1 - 0.018 15.3 5.0 0.018 15.3 5.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42552.1 - 0.21 12.5 18.5 0.36 11.8 3.7 4.9 2 1 2 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.18 KXZ42552.1 - 4.1 7.6 11.1 0.11 12.6 4.3 1.9 2 0 0 2 2 2 0 MYND finger PEMT PF04191.13 KXZ42553.1 - 1.5e-10 41.4 3.4 1.5e-10 41.4 3.4 1.9 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 KXZ42553.1 - 0.014 15.8 0.2 0.028 14.8 0.2 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Seryl_tRNA_N PF02403.22 KXZ42555.1 - 9.4 6.5 13.0 13 6.1 1.6 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_60s PF00428.19 KXZ42556.1 - 1.5e-24 86.4 7.9 1.8e-24 86.2 7.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein GPAT_N PF14829.6 KXZ42557.1 - 1e-22 79.9 0.0 2.4e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal Acyltransferase PF01553.21 KXZ42557.1 - 2.9e-14 52.9 0.0 5.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SAC3_GANP PF03399.16 KXZ42558.1 - 2.7e-49 168.1 0.0 4.5e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family Chloroa_b-bind PF00504.21 KXZ42559.1 - 8.1e-13 49.2 5.0 1.6e-08 35.2 1.4 2.2 1 1 1 2 2 2 2 Chlorophyll A-B binding protein Retrotrans_gag PF03732.17 KXZ42560.1 - 0.00026 21.2 0.0 0.00044 20.5 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KXZ42560.1 - 0.14 12.2 3.0 0.25 11.5 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Ank_2 PF12796.7 KXZ42561.1 - 9.6e-69 228.0 4.5 1.1e-15 58.0 0.0 6.7 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42561.1 - 4.9e-64 211.9 0.7 7.9e-12 45.5 0.0 6.5 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42561.1 - 1.2e-61 202.6 7.0 1.1e-07 31.9 0.1 9.9 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 KXZ42561.1 - 5.1e-57 183.1 0.1 4.2e-06 26.7 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 KXZ42561.1 - 1.4e-50 168.7 8.2 5.4e-11 42.5 0.1 9.0 1 1 8 9 9 9 8 Ankyrin repeats (many copies) DUF2384 PF09722.10 KXZ42561.1 - 1.1e-05 25.4 0.7 5.5 7.1 0.0 6.4 6 1 1 7 7 7 1 Protein of unknown function (DUF2384) DUF4988 PF16378.5 KXZ42561.1 - 0.0071 16.0 0.3 2.8 7.6 0.0 3.7 2 1 0 3 3 3 1 Domain of unknown function NDUF_B12 PF08122.12 KXZ42561.1 - 0.059 13.4 0.2 1.5 8.9 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family GST_N_5 PF18485.1 KXZ42561.1 - 0.62 10.5 5.1 0.29 11.5 0.2 3.0 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain DUF1843 PF08898.10 KXZ42561.1 - 4.1 8.0 10.9 9 6.9 0.1 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DUF5515 PF17635.2 KXZ42562.1 - 1.7 9.4 33.9 1.4 9.7 6.9 4.3 1 1 3 4 4 4 0 Family of unknown function (DUF5515) Transposase_21 PF02992.14 KXZ42563.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 EcsB PF05975.12 KXZ42565.1 - 0.1 11.4 0.4 0.2 10.4 0.4 1.4 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Glyco_trans_2_3 PF13632.6 KXZ42565.1 - 0.14 12.0 2.8 0.31 10.9 2.8 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF2614 PF11023.8 KXZ42566.1 - 0.049 13.7 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain TRP PF06011.12 KXZ42567.1 - 2.2e-05 23.4 10.9 2.2e-05 23.4 10.9 1.8 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel Ser_hydrolase PF06821.13 KXZ42567.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Chlam_PMP PF02415.17 KXZ42568.1 - 1.1e-13 50.7 78.9 0.18 12.3 1.5 11.6 11 1 0 11 11 11 10 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4256 PF14066.6 KXZ42568.1 - 0.014 15.1 0.3 7.8 6.1 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4256) Phage_spike PF18715.1 KXZ42568.1 - 0.21 11.7 58.5 4.8 7.3 0.4 9.8 6 2 4 10 10 10 0 Phage spike trimer Chlam_PMP PF02415.17 KXZ42569.1 - 2.4e-06 27.6 86.5 0.044 14.3 1.2 12.6 13 1 0 13 13 13 8 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat HepII_C PF18675.1 KXZ42569.1 - 0.22 11.6 14.3 6.3 7.0 0.2 5.3 4 2 2 6 6 6 0 Heparinase II C-terminal domain HtaA PF04213.13 KXZ42569.1 - 0.42 11.1 4.6 0.97 9.9 1.1 3.1 2 2 0 2 2 2 0 Htaa Phage_spike PF18715.1 KXZ42569.1 - 1 9.5 44.7 6.5 6.9 1.2 9.4 9 0 0 9 9 9 0 Phage spike trimer XK-related PF09815.9 KXZ42571.1 - 0.008 15.3 0.8 0.0085 15.2 0.8 1.1 1 0 0 1 1 1 1 XK-related protein HYR PF02494.16 KXZ42572.1 - 0.0006 20.1 2.2 0.00093 19.5 2.2 1.2 1 0 0 1 1 1 1 HYR domain PAP2 PF01569.21 KXZ42573.1 - 0.006 16.4 1.4 0.0082 15.9 0.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily RCC1_2 PF13540.6 KXZ42574.1 - 2.9e-18 65.2 10.1 2e-09 37.0 1.2 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXZ42574.1 - 3e-09 37.3 11.3 8.9e-05 23.0 0.1 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_9 PF00759.19 KXZ42576.1 - 5.3e-64 217.1 14.9 7.1e-64 216.7 14.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KXZ42577.1 - 1.4e-66 225.7 11.6 1.7e-66 225.4 11.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 PFK PF00365.20 KXZ42579.1 - 3.5e-43 148.0 0.0 5.2e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase FAST_1 PF06743.15 KXZ42580.1 - 6.4e-06 26.0 0.0 0.15 12.0 0.0 3.3 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KXZ42580.1 - 2.1e-05 24.5 0.0 0.0001 22.3 0.0 1.9 2 0 0 2 2 2 1 RAP domain MTES_1575 PF18741.1 KXZ42580.1 - 0.02 15.0 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 REase_MTES_1575 SUKH-4 PF14435.6 KXZ42580.1 - 0.13 12.3 5.2 0.33 11.0 0.8 3.2 3 0 0 3 3 3 0 SUKH-4 immunity protein Rieske PF00355.26 KXZ42581.1 - 1.4e-19 69.8 0.0 2.7e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ42581.1 - 2e-08 34.2 0.0 4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase Trp_oprn_chp PF09534.10 KXZ42581.1 - 0.0068 16.2 15.7 0.015 15.1 15.7 1.6 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tom22 PF04281.13 KXZ42582.1 - 1.4e-09 37.9 0.2 1.6e-09 37.7 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Complex1_LYR_2 PF13233.6 KXZ42583.1 - 2.7e-14 53.7 0.1 3.3e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXZ42583.1 - 0.00064 19.7 0.0 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KXZ42583.1 - 0.077 13.6 0.2 0.17 12.5 0.2 1.7 1 1 0 1 1 1 0 Complex1_LYR-like RRM_1 PF00076.22 KXZ42584.1 - 1.1e-27 95.6 0.1 2.4e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ42584.1 - 0.00012 22.1 0.0 0.00031 20.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif DUF2457 PF10446.9 KXZ42584.1 - 0.043 13.0 26.3 0.058 12.5 26.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SRP-alpha_N PF04086.13 KXZ42584.1 - 0.35 10.8 14.6 0.44 10.4 14.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RAP1 PF07218.11 KXZ42584.1 - 6.9 4.8 9.3 8.2 4.6 9.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SOBP PF15279.6 KXZ42584.1 - 8.4 6.9 14.7 10 6.7 14.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein QWRF PF04484.12 KXZ42584.1 - 8.8 6.0 19.4 11 5.7 19.4 1.1 1 0 0 1 1 1 0 QWRF family PP2C PF00481.21 KXZ42585.1 - 5.6e-28 98.3 0.0 1.9e-19 70.4 0.0 3.0 3 0 0 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 KXZ42585.1 - 0.0003 20.8 0.1 0.00076 19.4 0.0 1.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXZ42585.1 - 0.0032 17.1 5.5 0.013 15.1 2.3 2.9 2 2 0 2 2 2 1 Protein phosphatase 2C DUF3446 PF11928.8 KXZ42585.1 - 0.16 12.3 11.4 0.48 10.8 11.4 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain DUF1180 PF06679.12 KXZ42585.1 - 1.8 9.0 9.9 0.57 10.6 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Eno-Rase_FAD_bd PF07055.12 KXZ42586.1 - 0.011 16.1 0.2 0.017 15.6 0.2 1.3 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Methyltransf_34 PF11312.8 KXZ42586.1 - 0.019 14.2 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase K_channel_TID PF07941.11 KXZ42587.1 - 0.00081 19.8 11.6 0.00081 19.8 11.6 5.2 4 1 1 5 5 5 1 Potassium channel Kv1.4 tandem inactivation domain SDA1 PF05285.12 KXZ42587.1 - 0.0037 16.7 0.3 0.005 16.3 0.3 1.1 1 0 0 1 1 1 1 SDA1 TFIIE-A_C PF11521.8 KXZ42587.1 - 0.16 12.3 5.4 0.3 11.4 5.4 1.4 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DUF4637 PF15470.6 KXZ42587.1 - 7.7 6.2 9.3 14 5.4 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) FIST PF08495.10 KXZ42588.1 - 0.00029 20.9 0.7 0.00029 20.9 0.7 1.9 2 1 0 2 2 2 1 FIST N domain F-box-like PF12937.7 KXZ42588.1 - 0.0008 19.3 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ42588.1 - 0.003 17.4 0.2 0.0059 16.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain Serglycin PF04360.12 KXZ42588.1 - 1.2 9.1 2.9 1.8 8.5 2.9 1.2 1 0 0 1 1 1 0 Serglycin BTB PF00651.31 KXZ42589.1 - 5.9e-18 65.1 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Glutaredoxin PF00462.24 KXZ42590.1 - 8e-16 58.0 0.0 1.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KXZ42590.1 - 0.00056 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 KXZ42590.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) PKS_DE PF18369.1 KXZ42591.1 - 0.029 14.9 0.0 0.029 14.9 0.0 3.4 3 1 1 4 4 4 0 Polyketide synthase dimerisation element domain UDPG_MGDP_dh_N PF03721.14 KXZ42592.1 - 9.1e-64 214.5 0.2 1.4e-63 213.8 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KXZ42592.1 - 1.9e-34 118.2 0.0 6.7e-34 116.5 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KXZ42592.1 - 7.5e-32 109.4 0.0 1.4e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain ApbA PF02558.16 KXZ42592.1 - 0.008 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXZ42592.1 - 0.01 15.7 0.0 0.031 14.2 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXZ42592.1 - 0.054 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KXZ42592.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF2423 PF10338.9 KXZ42593.1 - 0.076 13.3 1.8 0.076 13.3 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) BAF1_ABF1 PF04684.13 KXZ42593.1 - 0.15 11.1 2.3 0.2 10.7 2.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.32 KXZ42593.1 - 0.23 12.4 1.4 35 5.5 0.2 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat PDDEXK_6 PF04720.12 KXZ42595.1 - 1.5e-16 61.0 0.1 1.5e-16 61.0 0.1 2.0 2 0 0 2 2 2 1 PDDEXK-like family of unknown function DNA_ligase_A_N PF04675.14 KXZ42596.1 - 2e-29 103.1 0.0 3.1e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KXZ42596.1 - 8.7e-17 61.4 0.0 1.8e-11 44.1 0.0 3.0 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KXZ42596.1 - 4.2e-16 59.4 0.0 1.3e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Trypan_PARP PF05887.11 KXZ42597.1 - 0.00027 20.9 28.0 0.00038 20.4 28.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF2052 PF09747.9 KXZ42597.1 - 0.39 10.8 16.6 0.38 10.8 16.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_polI_A34 PF08208.11 KXZ42597.1 - 0.41 10.7 10.0 0.41 10.7 10.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 KXZ42597.1 - 1 9.1 15.5 1.1 9.1 15.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 KXZ42597.1 - 1.2 7.8 6.4 1.1 8.0 6.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2807 PF10988.8 KXZ42597.1 - 1.5 8.6 6.8 5.2 6.8 6.8 1.8 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Raftlin PF15250.6 KXZ42597.1 - 2.2 6.9 6.8 1.9 7.1 6.8 1.0 1 0 0 1 1 1 0 Raftlin NESP55 PF06390.12 KXZ42597.1 - 4.8 6.7 30.8 2.6e+02 1.0 30.8 2.1 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) TMEM119 PF15724.5 KXZ42597.1 - 6.6 6.7 21.6 7 6.6 21.6 1.1 1 0 0 1 1 1 0 TMEM119 family ABC_tran PF00005.27 KXZ42598.1 - 0.0027 18.2 0.0 0.0045 17.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXZ42600.1 - 5.6e-06 25.9 5.5 6.4e-06 25.7 5.5 1.0 1 0 0 1 1 1 1 ABC-2 type transporter SNF PF00209.18 KXZ42600.1 - 0.0098 14.6 0.8 0.011 14.4 0.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ion_trans PF00520.31 KXZ42600.1 - 0.018 14.3 2.0 0.024 13.8 2.0 1.1 1 0 0 1 1 1 0 Ion transport protein TRP PF06011.12 KXZ42603.1 - 1.2e-05 24.3 0.6 1.2e-05 24.3 0.6 1.6 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel Chlam_PMP PF02415.17 KXZ42604.1 - 3.4e-24 83.7 140.5 0.039 14.4 1.6 16.4 16 0 0 16 16 16 15 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat MHC_II_alpha PF00993.20 KXZ42605.1 - 0.015 14.9 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain Transposase_21 PF02992.14 KXZ42606.1 - 0.00093 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KXZ42606.1 - 0.0046 16.6 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Pkinase PF00069.25 KXZ42607.1 - 1.4e-10 41.0 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42607.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM126 PF07114.11 KXZ42608.1 - 0.016 14.6 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 126 Raffinose_syn PF05691.12 KXZ42609.1 - 7.9e-157 523.2 0.0 1.1e-89 301.2 0.0 3.0 3 0 0 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 CAP_N PF01213.19 KXZ42609.1 - 1.1 8.7 2.6 2 7.8 2.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MAD PF05557.13 KXZ42610.1 - 1.1e-16 60.5 10.8 5.3e-16 58.2 9.1 4.4 2 2 1 3 3 3 2 Mitotic checkpoint protein Tropomyosin PF00261.20 KXZ42610.1 - 0.0086 15.5 9.4 0.0086 15.5 9.4 6.7 5 2 0 6 6 6 3 Tropomyosin Shugoshin_N PF07558.11 KXZ42610.1 - 0.058 13.3 0.1 0.058 13.3 0.1 4.2 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Fez1 PF06818.15 KXZ42610.1 - 0.36 11.3 54.4 0.024 15.1 7.9 4.7 2 2 1 4 4 4 0 Fez1 TMF_DNA_bd PF12329.8 KXZ42610.1 - 8.8 6.4 47.2 1.2 9.1 0.7 8.3 7 2 1 8 8 8 0 TATA element modulatory factor 1 DNA binding Raffinose_syn PF05691.12 KXZ42611.1 - 8e-12 43.8 0.0 8.7e-12 43.7 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 TPR_2 PF07719.17 KXZ42612.1 - 2.7e-29 98.9 17.5 5.3e-05 23.0 0.1 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ42612.1 - 7.1e-25 85.8 18.9 8e-07 28.6 0.3 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ42612.1 - 6.6e-22 77.9 12.7 4.7e-07 30.4 0.4 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42612.1 - 8.4e-20 69.8 15.4 0.013 16.2 0.1 9.0 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ42612.1 - 2.1e-18 66.3 15.0 0.00055 20.2 0.1 7.1 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ42612.1 - 3e-16 59.7 14.8 0.00012 22.5 0.5 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ42612.1 - 7.7e-13 47.6 7.4 0.0018 18.4 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ42612.1 - 1.6e-08 34.3 18.5 0.0002 21.5 0.3 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ42612.1 - 5.2e-08 33.0 8.7 7 7.5 0.1 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ42612.1 - 7.2e-07 28.8 16.1 0.24 11.5 0.0 8.2 8 1 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ42612.1 - 1.4e-06 28.4 18.8 0.21 11.8 0.0 5.9 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KXZ42612.1 - 3.3e-06 26.7 12.4 0.00097 18.8 0.6 5.9 5 1 1 6 6 6 2 TPR repeat TPR_9 PF13371.6 KXZ42612.1 - 0.00011 22.3 10.0 2 8.7 0.1 5.7 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ42612.1 - 0.0034 16.7 3.3 0.0046 16.2 0.1 2.7 3 1 0 4 4 4 1 Tetratricopeptide repeat DUF5112 PF17139.4 KXZ42612.1 - 0.0055 16.2 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5112) TPR_10 PF13374.6 KXZ42612.1 - 0.015 15.1 11.5 0.093 12.6 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXZ42612.1 - 0.023 15.1 2.4 1.2 9.6 0.0 3.9 5 0 0 5 5 5 0 Alkyl sulfatase dimerisation PPTA PF01239.22 KXZ42612.1 - 0.091 12.5 0.1 0.9 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Pkinase_Tyr PF07714.17 KXZ42613.1 - 1.1e-26 93.7 0.0 3.1e-26 92.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ42613.1 - 1.5e-26 93.3 0.0 4.4e-26 91.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Rhomboid PF01694.22 KXZ42613.1 - 1.2e-20 74.1 13.3 1.2e-20 74.1 13.3 2.0 2 0 0 2 2 2 1 Rhomboid family APH PF01636.23 KXZ42613.1 - 4.4e-05 23.5 0.1 0.0036 17.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1751 PF08551.10 KXZ42613.1 - 0.0032 18.0 0.2 0.0061 17.1 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) PLRV_ORF5 PF01690.17 KXZ42613.1 - 2.7 6.6 5.2 4.2 6.0 5.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TPT PF03151.16 KXZ42614.1 - 5.1e-08 32.6 1.7 1.5e-05 24.5 0.1 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KXZ42614.1 - 0.14 12.3 0.3 0.14 12.3 0.3 2.4 2 0 0 2 2 2 0 EamA-like transporter family Pkinase PF00069.25 KXZ42615.1 - 2.7e-18 66.3 0.0 4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ42615.1 - 2e-07 30.1 0.0 2.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ42615.1 - 2e-06 27.3 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ42615.1 - 0.0049 16.2 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ42615.1 - 0.049 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PilX PF13681.6 KXZ42615.1 - 0.094 13.1 0.1 24 5.4 0.0 3.6 3 1 0 3 3 3 0 Type IV pilus assembly protein PilX C-term V_ATPase_I PF01496.19 KXZ42616.1 - 0.0087 14.0 20.2 0.24 9.3 0.6 2.2 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family Spc42p PF11544.8 KXZ42616.1 - 0.015 15.3 2.3 0.015 15.3 2.3 3.4 3 0 0 3 3 3 0 Spindle pole body component Spc42p NleF_casp_inhib PF16809.5 KXZ42616.1 - 0.079 12.9 14.8 0.11 12.5 2.6 2.9 3 1 0 3 3 3 0 NleF caspase inhibitor Bacillus_HBL PF05791.11 KXZ42616.1 - 0.14 11.9 17.6 0.017 15.0 3.8 3.9 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) HRI1 PF16815.5 KXZ42616.1 - 0.23 11.2 6.3 0.4 10.4 6.0 1.6 1 1 0 1 1 1 0 Protein HRI1 FlaC_arch PF05377.11 KXZ42616.1 - 0.59 10.6 20.0 1.4 9.4 1.9 5.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) RPW8 PF05659.11 KXZ42616.1 - 0.68 9.6 10.2 1.4 8.6 0.5 3.5 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Imm30 PF15565.6 KXZ42616.1 - 0.78 9.9 7.6 1.3 9.1 0.9 2.6 2 1 0 2 2 2 0 Immunity protein 30 DUF3584 PF12128.8 KXZ42616.1 - 1.6 6.1 33.5 1.2 6.6 28.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) LPP PF04728.13 KXZ42616.1 - 4.1 7.9 8.4 2.3 8.7 0.1 4.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF948 PF06103.11 KXZ42616.1 - 4.7 7.5 10.6 15 5.9 0.1 4.0 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KXZ42616.1 - 4.8 7.3 15.6 22 5.1 0.6 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 KXZ42616.1 - 6.7 7.0 30.4 0.14 12.4 3.1 3.5 1 1 2 3 3 3 0 Zinc finger-containing protein NPV_P10 PF05531.12 KXZ42616.1 - 8 7.0 7.1 9.7 6.7 0.1 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein zn-ribbon_14 PF16503.5 KXZ42617.1 - 3.1e-18 64.9 1.5 3.1e-18 64.9 1.5 3.4 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 KXZ42617.1 - 5.4e-13 49.1 0.0 1.4e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 PP-loop family CTU2 PF10288.9 KXZ42617.1 - 0.023 14.9 1.0 0.13 12.6 0.0 2.3 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 tRNA_Me_trans PF03054.16 KXZ42617.1 - 0.028 13.2 0.0 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 tRNA methyl transferase IRF-2BP1_2 PF11261.8 KXZ42617.1 - 0.094 12.3 0.7 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger Sacchrp_dh_NADP PF03435.18 KXZ42618.1 - 2e-15 57.2 0.0 3.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXZ42618.1 - 5.4e-07 29.3 0.0 8.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXZ42618.1 - 0.00015 21.7 1.4 0.00015 21.7 0.2 1.7 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KXZ42618.1 - 0.00018 21.4 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXZ42618.1 - 0.0002 20.9 0.1 0.00033 20.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KXZ42618.1 - 0.0019 17.6 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KXZ42618.1 - 0.0035 17.8 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KXZ42618.1 - 0.0079 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXZ42618.1 - 0.0083 16.2 0.1 0.02 15.0 0.1 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KXZ42618.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXZ42618.1 - 0.039 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GFO_IDH_MocA PF01408.22 KXZ42618.1 - 0.041 14.7 0.0 0.072 13.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.19 KXZ42618.1 - 0.081 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2336 PF10098.9 KXZ42618.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Ank_2 PF12796.7 KXZ42619.1 - 4e-14 52.9 0.0 3.7e-07 30.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ42619.1 - 4e-10 39.7 0.2 3.5e-07 30.4 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42619.1 - 4e-08 32.9 0.0 0.0014 19.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXZ42619.1 - 2.9e-07 30.6 0.1 0.0029 18.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KXZ42619.1 - 1.2e-06 28.9 0.0 0.12 13.0 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF2384 PF09722.10 KXZ42619.1 - 0.015 15.3 0.3 0.17 11.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2384) AAA PF00004.29 KXZ42620.1 - 8.9e-36 123.2 0.0 1.7e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ42620.1 - 1.6e-05 25.2 0.0 0.0025 18.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ42620.1 - 2.3e-05 24.8 0.7 0.00032 21.1 0.7 2.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXZ42620.1 - 5.3e-05 23.0 0.0 0.00014 21.6 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KXZ42620.1 - 0.00012 21.9 0.0 0.00028 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXZ42620.1 - 0.00032 20.7 0.1 0.0028 17.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXZ42620.1 - 0.00044 19.6 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KXZ42620.1 - 0.00063 19.4 0.1 0.0036 16.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KXZ42620.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXZ42620.1 - 0.0024 17.3 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KXZ42620.1 - 0.0025 18.0 0.0 0.0062 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXZ42620.1 - 0.0058 16.8 3.1 0.007 16.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXZ42620.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KXZ42620.1 - 0.039 13.6 0.0 0.25 11.1 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXZ42620.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KXZ42620.1 - 0.053 14.1 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXZ42620.1 - 0.072 13.5 0.0 0.21 12.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 KXZ42620.1 - 0.073 13.3 0.8 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXZ42620.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 KXZ42620.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXZ42620.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXZ42620.1 - 0.16 11.9 0.0 6.3 6.6 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KXZ42620.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TniB PF05621.11 KXZ42620.1 - 0.2 11.0 0.0 2.2 7.7 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein DUF5326 PF17260.2 KXZ42621.1 - 0.03 14.4 0.3 0.056 13.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Serinc PF03348.15 KXZ42621.1 - 0.2 10.5 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) WD40 PF00400.32 KXZ42624.1 - 2.6e-21 75.5 15.0 5.2e-06 27.1 0.1 7.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ42624.1 - 1e-11 45.0 0.2 0.013 15.7 0.0 4.6 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ42624.1 - 0.0037 17.2 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXZ42624.1 - 0.005 15.8 0.1 0.064 12.2 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Patatin PF01734.22 KXZ42625.1 - 2.5e-11 44.2 1.0 4.1e-10 40.2 0.3 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase CybS PF05328.12 KXZ42626.1 - 5.3e-13 48.8 0.1 7e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 KXZ42627.1 - 3.7e-11 43.1 0.1 5.4e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit LisH_TPL PF17814.1 KXZ42628.1 - 3.3e-10 39.4 0.7 6e-10 38.6 0.7 1.4 1 0 0 1 1 1 1 LisH-like dimerisation domain WD40 PF00400.32 KXZ42628.1 - 0.026 15.4 0.0 0.056 14.3 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat Phtf-FEM1B_bdg PF12129.8 KXZ42628.1 - 0.18 11.6 1.1 0.28 11.0 1.1 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Fijivirus_P9-2 PF06837.11 KXZ42629.1 - 0.15 11.5 0.2 0.18 11.2 0.2 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein DnaJ_C PF01556.18 KXZ42631.1 - 1.9e-36 125.4 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXZ42631.1 - 9.2e-27 93.0 6.2 1.4e-26 92.4 6.2 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KXZ42631.1 - 0.18 11.8 0.2 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein FtsK_SpoIIIE PF01580.18 KXZ42632.1 - 0.077 12.3 1.1 0.15 11.4 0.8 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PET117 PF15786.5 KXZ42632.1 - 6.3 7.1 9.0 2.2 8.6 0.6 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Beta_helix PF13229.6 KXZ42633.1 - 1.9e-11 44.1 0.0 3.2e-06 27.1 0.0 3.2 3 0 0 3 3 3 3 Right handed beta helix region Topo-VIb_trans PF09239.11 KXZ42634.1 - 7.2e-52 175.4 0.0 1.2e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer FbpA PF05833.11 KXZ42634.1 - 0.0003 19.7 0.0 0.00045 19.1 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) SDH_alpha PF03313.15 KXZ42634.1 - 0.0067 16.1 3.3 0.013 15.2 3.3 1.5 1 0 0 1 1 1 1 Serine dehydratase alpha chain Ribosomal_60s PF00428.19 KXZ42634.1 - 5.5 7.6 18.0 0.42 11.2 12.7 1.9 2 1 0 2 2 2 0 60s Acidic ribosomal protein SAP PF02037.27 KXZ42635.1 - 0.0031 17.2 0.2 0.007 16.1 0.1 1.7 2 0 0 2 2 2 1 SAP domain BST2 PF16716.5 KXZ42636.1 - 7e-05 23.3 5.5 7e-05 23.3 5.5 9.5 5 2 6 11 11 11 1 Bone marrow stromal antigen 2 DUF4407 PF14362.6 KXZ42636.1 - 0.00036 20.0 5.7 0.00036 20.0 5.7 6.4 1 1 6 7 7 7 2 Domain of unknown function (DUF4407) Sugarporin_N PF11471.8 KXZ42636.1 - 0.014 15.3 2.6 0.014 15.3 2.6 14.1 12 3 4 16 16 16 0 Maltoporin periplasmic N-terminal extension Fib_alpha PF08702.10 KXZ42636.1 - 0.014 15.6 42.0 0.049 13.8 3.1 7.0 4 2 3 7 7 7 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KXZ42636.1 - 3.9 8.0 16.1 13 6.2 0.1 6.4 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) Motilin_assoc PF04643.12 KXZ42636.1 - 5.3 7.0 8.7 20 5.1 0.0 4.1 4 0 0 4 4 4 0 Motilin/ghrelin-associated peptide UQ_con PF00179.26 KXZ42639.1 - 3.1e-24 85.2 0.0 2e-23 82.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme SBP_bac_1 PF01547.25 KXZ42640.1 - 7.7e-09 35.9 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Guanylate_cyc PF00211.20 KXZ42640.1 - 9.9e-05 22.0 0.0 0.0017 18.0 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain SBP_bac_8 PF13416.6 KXZ42640.1 - 0.00034 20.5 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Ank_2 PF12796.7 KXZ42641.1 - 6e-24 84.4 5.9 9.3e-14 51.8 0.7 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ42641.1 - 2.5e-19 68.8 5.8 2.3e-05 24.6 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KXZ42641.1 - 3.2e-18 63.9 4.1 0.00078 19.7 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXZ42641.1 - 1e-17 63.9 6.6 9.2e-05 22.7 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ42641.1 - 3.4e-12 46.6 4.4 0.00051 20.6 0.8 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) CCDC-167 PF15188.6 KXZ42643.1 - 0.0075 16.6 15.3 0.0075 16.6 15.3 1.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.19 KXZ42643.1 - 0.09 10.7 2.2 0.11 10.4 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SmpB PF01668.18 KXZ42643.1 - 0.22 11.4 8.1 1.5 8.7 0.4 2.4 1 1 1 2 2 2 0 SmpB protein Exonuc_VII_L PF02601.15 KXZ42643.1 - 0.23 11.0 2.0 0.28 10.7 2.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 KXZ42643.1 - 0.44 11.2 8.3 0.69 10.6 8.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA FapA PF03961.13 KXZ42643.1 - 0.98 7.9 8.0 1.2 7.7 8.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlxA PF14282.6 KXZ42643.1 - 2.9 7.9 11.3 4.9 7.2 11.3 1.4 1 1 0 1 1 1 0 FlxA-like protein Styelin PF17562.2 KXZ42643.1 - 5.8 7.3 6.6 0.87 10.0 0.4 2.3 2 0 0 2 2 2 0 Styelin CAP_N PF01213.19 KXZ42644.1 - 0.31 10.5 17.1 0.019 14.5 11.2 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Epimerase PF01370.21 KXZ42645.1 - 2.1e-46 158.3 0.0 2.7e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ42645.1 - 1.2e-26 93.9 0.0 3.1e-25 89.3 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXZ42645.1 - 2.1e-09 36.8 0.0 2.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXZ42645.1 - 1.1e-06 28.7 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXZ42645.1 - 1.9e-05 23.9 0.0 0.004 16.3 0.1 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXZ42645.1 - 8.3e-05 21.9 0.0 0.0061 15.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KXZ42645.1 - 0.0025 16.9 0.0 0.082 12.0 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KXZ42645.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 KXZ42645.1 - 0.12 11.9 0.1 1 8.9 0.1 2.1 1 1 0 1 1 1 0 NmrA-like family FATC PF02260.20 KXZ42647.1 - 3.2e-10 39.6 0.0 4.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 FATC domain Aldedh PF00171.22 KXZ42649.1 - 4.5e-129 430.9 0.0 5.8e-129 430.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SipA_VBS PF17985.1 KXZ42649.1 - 0.27 11.2 0.6 0.69 9.9 0.6 1.6 1 0 0 1 1 1 0 SipA vinculin binding site zf-Tim10_DDP PF02953.15 KXZ42650.1 - 4.1e-16 58.4 5.2 4.1e-16 58.4 5.2 1.7 2 0 0 2 2 2 1 Tim10/DDP family zinc finger TolA_bind_tri PF16331.5 KXZ42651.1 - 0.043 13.9 1.7 0.075 13.1 1.7 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation MerR-DNA-bind PF09278.11 KXZ42651.1 - 0.072 13.6 2.4 1.1 9.8 0.6 2.3 2 0 0 2 2 2 0 MerR, DNA binding LcnG-beta PF11632.8 KXZ42654.1 - 0.22 11.5 2.0 0.46 10.5 2.0 1.5 1 0 0 1 1 1 0 Lactococcin G-beta DUF220 PF02713.14 KXZ42655.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF220 Diphthami_syn_2 PF01902.17 KXZ42656.1 - 1.8e-33 115.9 0.0 2.8e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KXZ42656.1 - 4.3e-19 68.7 0.0 1.7e-07 31.2 0.0 4.4 4 0 0 4 4 4 2 Endoribonuclease L-PSP Nodulin PF02451.15 KXZ42656.1 - 0.025 14.1 0.2 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 Nodulin tRNA_Me_trans PF03054.16 KXZ42656.1 - 0.047 12.5 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PET PF06297.14 KXZ42657.1 - 0.042 14.2 0.6 0.048 14.0 0.6 1.1 1 0 0 1 1 1 0 PET Domain DUF1664 PF07889.12 KXZ42657.1 - 0.059 13.4 0.6 0.062 13.4 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Dermcidin PF15291.6 KXZ42657.1 - 0.078 13.5 0.9 0.081 13.5 0.9 1.1 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide PAS_9 PF13426.7 KXZ42658.1 - 7.9e-05 22.9 0.0 0.084 13.1 0.0 3.8 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 KXZ42658.1 - 0.047 13.7 0.0 17 5.4 0.0 3.9 5 0 0 5 5 5 0 PAS fold Pex24p PF06398.11 KXZ42658.1 - 0.15 11.0 3.4 1 8.3 0.3 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin F-box_5 PF18511.1 KXZ42658.1 - 0.29 10.8 0.9 0.75 9.4 0.9 1.7 1 0 0 1 1 1 0 F-box Chlam_PMP PF02415.17 KXZ42659.1 - 0.025 15.1 0.5 0.025 15.1 0.5 7.6 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pirin_C_2 PF17954.1 KXZ42659.1 - 0.25 11.5 1.0 3.8 7.7 0.1 2.7 2 1 2 4 4 4 0 Quercetinase C-terminal cupin domain Chlam_PMP PF02415.17 KXZ42660.1 - 2.2e-06 27.8 40.1 0.023 15.1 1.7 5.6 5 1 0 5 5 5 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Peptidase_C23 PF05379.11 KXZ42660.1 - 0.11 12.6 3.4 2.1 8.5 0.3 3.0 1 1 1 3 3 3 0 Carlavirus endopeptidase CBM64 PF18666.1 KXZ42660.1 - 0.2 11.8 3.4 4 7.6 0.4 2.6 1 1 0 2 2 2 0 Carbohydrate-binding module 64 zf-CGNR PF11706.8 KXZ42660.1 - 0.44 10.4 1.8 23 4.9 0.2 2.4 2 0 0 2 2 2 0 CGNR zinc finger TRP PF06011.12 KXZ42661.1 - 1.4e-06 27.3 1.2 1.9e-06 26.9 1.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP PF06011.12 KXZ42662.1 - 8.6e-08 31.3 5.1 1.2e-07 30.8 5.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF716 PF04819.12 KXZ42662.1 - 0.13 11.9 7.1 0.52 10.0 1.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF716) Chlam_PMP PF02415.17 KXZ42663.1 - 4.7e-17 61.3 138.6 0.032 14.7 4.7 18.2 18 0 0 18 18 18 15 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glyco_hydro_9 PF00759.19 KXZ42665.1 - 2.5e-60 205.1 8.8 8e-37 127.6 4.8 2.1 1 1 0 2 2 2 2 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KXZ42667.1 - 9.9e-65 219.6 13.6 1.1e-64 219.4 13.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Oxysterol_BP PF01237.18 KXZ42668.1 - 2.1e-07 30.1 0.1 4.1e-07 29.2 0.1 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.18 KXZ42669.1 - 4e-34 118.1 0.0 4.7e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein PX PF00787.24 KXZ42669.1 - 0.061 13.3 0.0 9.1 6.3 0.0 2.2 2 0 0 2 2 2 0 PX domain Orthopox_A5L PF06193.11 KXZ42669.1 - 0.23 10.8 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Ank_2 PF12796.7 KXZ42670.1 - 1.7e-09 38.1 0.7 0.018 15.6 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42670.1 - 7.7e-08 32.7 3.0 2.4 8.8 0.0 5.6 4 3 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ42670.1 - 0.0019 18.5 9.8 2.7 8.4 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) HTH_32 PF13565.6 KXZ42670.1 - 0.12 13.0 2.1 24 5.7 0.1 3.2 3 0 0 3 3 3 0 Homeodomain-like domain Ank_2 PF12796.7 KXZ42671.1 - 1.9e-16 60.4 0.8 0.013 16.1 0.0 5.1 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42671.1 - 3e-15 56.4 10.8 0.037 14.6 0.0 7.3 6 2 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42671.1 - 3.9e-07 29.9 6.1 89 4.2 0.0 9.4 10 0 0 10 10 10 0 Ankyrin repeat Ank_5 PF13857.6 KXZ42671.1 - 1e-05 25.7 12.1 2.3 8.7 0.0 7.5 6 2 2 8 8 8 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42673.1 - 4.1e-09 36.9 0.0 0.085 13.5 0.0 5.3 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42673.1 - 8.7e-08 31.9 6.8 28 5.7 0.0 9.4 11 0 0 11 11 11 1 Ankyrin repeat Ank_4 PF13637.6 KXZ42673.1 - 2.4e-07 31.2 4.5 5.7 7.6 0.0 7.9 6 2 3 9 9 9 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ42673.1 - 1.9e-05 24.8 6.3 22 5.5 0.0 7.5 7 1 1 8 8 8 1 Ankyrin repeats (many copies) HTH_39 PF14090.6 KXZ42673.1 - 0.14 12.0 0.0 0.8 9.5 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Ank_4 PF13637.6 KXZ42674.1 - 1.5e-07 31.8 1.0 0.75 10.4 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42674.1 - 4.6e-06 27.1 0.0 0.76 10.4 0.1 3.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ42674.1 - 1.6e-05 25.1 5.2 0.31 11.4 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42674.1 - 0.0021 18.4 0.3 13 6.7 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 KXZ42675.1 - 1.8e-09 37.9 4.0 0.015 15.9 0.0 6.6 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42675.1 - 3.3e-09 37.2 0.0 0.14 12.8 0.0 4.6 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42675.1 - 1.7e-06 27.9 1.1 55 4.8 0.0 7.6 7 1 1 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ42675.1 - 0.0092 16.3 0.7 59 4.2 0.0 5.1 6 0 0 6 6 6 0 Ankyrin repeats (many copies) F-box-like PF12937.7 KXZ42676.1 - 0.026 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like Ank_4 PF13637.6 KXZ42677.1 - 2.8e-11 43.7 1.5 0.004 17.7 0.0 5.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42677.1 - 1.5e-06 28.7 0.0 1.2 9.8 0.0 4.2 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42677.1 - 0.00019 21.6 3.5 70 4.5 0.0 7.2 7 0 0 7 7 7 0 Ankyrin repeat DUF4224 PF13986.6 KXZ42677.1 - 0.024 14.5 1.7 20 5.2 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4224) Ank_4 PF13637.6 KXZ42679.1 - 9e-11 42.1 0.9 0.0032 18.0 0.1 5.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42679.1 - 4.5e-06 27.2 0.0 0.72 10.5 0.0 4.2 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42679.1 - 0.00018 21.7 2.8 85 4.2 0.0 7.0 7 0 0 7 7 7 0 Ankyrin repeat DUF4224 PF13986.6 KXZ42679.1 - 0.16 11.9 1.2 36 4.3 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4224) Chloroa_b-bind PF00504.21 KXZ42680.1 - 2.5e-08 34.6 1.9 8e-06 26.5 1.7 2.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Gal_Lectin PF02140.18 KXZ42681.1 - 7.5e-12 45.5 9.7 1.8e-06 28.3 0.4 3.3 3 0 0 3 3 3 2 Galactose binding lectin domain PAN_1 PF00024.26 KXZ42681.1 - 2.9e-06 27.1 5.6 0.29 11.1 0.1 3.6 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 KXZ42681.1 - 0.057 13.3 14.4 0.16 11.9 0.2 4.6 4 0 0 4 4 4 0 PAN domain PAN_3 PF08277.12 KXZ42681.1 - 0.28 11.0 3.4 15 5.4 0.5 2.5 2 0 0 2 2 2 0 PAN-like domain Pkinase PF00069.25 KXZ42683.1 - 7.5e-39 133.7 0.0 9.4e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42683.1 - 3.4e-23 82.3 0.0 4.2e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ42683.1 - 0.00061 18.7 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ42683.1 - 0.00091 19.2 0.3 0.21 11.5 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KXZ42683.1 - 0.0052 16.4 0.0 0.57 9.7 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Kinase-like PF14531.6 KXZ42683.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_127 PF07944.12 KXZ42683.1 - 0.068 11.7 0.1 0.09 11.3 0.1 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 CTP_transf_like PF01467.26 KXZ42685.1 - 0.00056 20.1 0.2 0.0013 19.0 0.2 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like UBD PF16455.5 KXZ42686.1 - 9.3e-25 86.9 0.0 1e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-binding domain TPR_1 PF00515.28 KXZ42687.1 - 0.00015 21.4 6.0 0.00036 20.2 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ42687.1 - 0.0068 16.4 0.2 0.0068 16.4 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ42687.1 - 0.13 12.7 2.2 1.2 9.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ42687.1 - 0.28 11.5 9.2 0.31 11.4 0.4 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ42687.1 - 0.32 10.7 6.1 3.9 7.2 0.1 3.3 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 KXZ42687.1 - 2.7 8.6 11.6 5.9 7.5 2.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42687.1 - 3.5 8.7 11.8 3.4 8.7 0.8 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat HELP PF03451.14 KXZ42689.1 - 3.4e-16 58.8 0.1 6.1e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 KXZ42689.1 - 0.053 13.8 0.0 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ42690.1 - 8.7e-16 58.0 14.8 0.065 14.1 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ42690.1 - 1.2e-07 31.9 0.0 0.0012 19.2 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ42690.1 - 0.13 11.2 0.1 5.5 5.8 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frataxin_Cyay PF01491.16 KXZ42691.1 - 3.4e-38 130.0 0.0 3.9e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain RNA_pol_Rbc25 PF08292.12 KXZ42692.1 - 3.9e-36 124.1 0.0 6.1e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KXZ42692.1 - 6.3e-17 61.7 0.2 9.5e-17 61.1 0.2 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KXZ42692.1 - 0.02 15.2 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 S1 RNA binding domain CDP-OH_P_transf PF01066.21 KXZ42693.1 - 3.2e-10 40.6 0.0 3.2e-10 40.6 0.0 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CopD PF05425.13 KXZ42693.1 - 0.0044 17.4 0.4 0.0044 17.4 0.4 2.3 3 0 0 3 3 3 1 Copper resistance protein D DUF3382 PF11862.8 KXZ42693.1 - 0.069 13.4 0.7 0.56 10.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Utp12 PF04003.12 KXZ42694.1 - 4.4e-17 62.3 0.1 6.2e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KXZ42694.1 - 1.6e-05 25.6 0.0 0.16 12.9 0.0 4.5 3 1 1 4 4 4 1 WD domain, G-beta repeat PQQ PF01011.21 KXZ42694.1 - 1.8e-05 24.5 0.5 0.011 15.6 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 KXZ42694.1 - 0.00013 21.7 2.0 0.0066 16.1 0.5 2.6 1 1 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KXZ42694.1 - 0.022 15.1 0.0 0.83 10.0 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 KXZ42694.1 - 2.3 7.5 6.7 0.29 10.4 2.3 1.7 2 0 0 2 2 2 0 BUD22 GATA PF00320.27 KXZ42695.1 - 1.3e-05 24.7 2.7 2.7e-05 23.7 2.7 1.5 1 0 0 1 1 1 1 GATA zinc finger fn3 PF00041.21 KXZ42697.1 - 4.6e-09 36.5 0.0 0.00024 21.4 0.0 2.3 2 0 0 2 2 2 2 Fibronectin type III domain DUF4959 PF16323.5 KXZ42697.1 - 0.0023 18.2 0.0 0.23 11.8 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4959) DUF2057 PF09829.9 KXZ42697.1 - 5.4 7.1 5.2 5.5 7.1 1.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TP_methylase PF00590.20 KXZ42698.1 - 9.3e-44 149.9 0.1 1.1e-43 149.7 0.1 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases RVT_1 PF00078.27 KXZ42699.1 - 7.6e-07 28.9 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEPN_Swt1 PF18731.1 KXZ42699.1 - 0.025 14.9 0.8 0.05 14.0 0.0 1.9 2 0 0 2 2 2 0 Swt1-like HEPN CCDC-167 PF15188.6 KXZ42699.1 - 0.92 9.9 10.2 1.7 9.0 10.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3584 PF12128.8 KXZ42699.1 - 1.4 6.3 6.6 1.9 5.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tho2 PF11262.8 KXZ42699.1 - 3.1 6.9 5.7 4.7 6.3 5.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Roc PF08477.13 KXZ42700.1 - 1.6e-16 60.6 0.0 2.6e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 KXZ42700.1 - 4.5e-09 36.8 0.0 4.5e-05 24.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Arf PF00025.21 KXZ42700.1 - 4.7e-08 32.7 0.0 6.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXZ42700.1 - 2.3e-07 30.6 0.0 3.9e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 Ras family Ank PF00023.30 KXZ42700.1 - 3.6e-06 27.2 0.1 0.00047 20.5 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXZ42700.1 - 2e-05 24.8 0.0 5.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Mg_chelatase PF01078.21 KXZ42700.1 - 8.2e-05 22.1 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Ank_3 PF13606.6 KXZ42700.1 - 0.00044 20.5 0.0 0.0069 16.8 0.0 2.7 3 0 0 3 3 2 1 Ankyrin repeat AAA_25 PF13481.6 KXZ42700.1 - 0.0049 16.5 0.1 0.0079 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ42700.1 - 0.015 15.6 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ank_4 PF13637.6 KXZ42700.1 - 0.022 15.4 0.0 0.11 13.1 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) IstB_IS21 PF01695.17 KXZ42700.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KXZ42700.1 - 0.028 14.8 0.2 0.048 14.0 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXZ42700.1 - 0.03 14.5 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXZ42700.1 - 0.031 14.2 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KXZ42700.1 - 0.039 14.5 0.0 0.064 13.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KXZ42700.1 - 0.08 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KXZ42700.1 - 0.088 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein PduV-EutP PF10662.9 KXZ42700.1 - 0.16 11.7 0.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KXZ42700.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KXZ42700.1 - 0.24 11.1 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KXZ42701.1 - 9e-23 80.8 0.0 1.5e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ42701.1 - 3.2e-17 63.0 0.0 1.4e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Ank PF00023.30 KXZ42701.1 - 4.1e-16 58.6 0.5 1.9e-06 28.0 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXZ42701.1 - 1.2e-14 54.4 0.0 5.7e-14 52.3 0.0 2.3 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ras PF00071.22 KXZ42701.1 - 4.3e-13 49.2 0.0 7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 KXZ42701.1 - 1.1e-12 48.3 0.0 4.1e-11 43.3 0.0 3.1 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ42701.1 - 2.7e-11 43.5 0.1 2.6e-08 34.0 0.0 3.4 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42701.1 - 1.3e-10 40.5 0.0 0.00077 19.7 0.0 4.4 4 0 0 4 4 3 2 Ankyrin repeat Arf PF00025.21 KXZ42701.1 - 5e-06 26.1 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXZ42701.1 - 0.00057 19.4 0.0 0.00097 18.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXZ42701.1 - 0.088 12.9 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXZ42701.1 - 0.23 10.8 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CLAG PF03805.13 KXZ42702.1 - 0.24 8.9 0.0 0.24 8.9 0.0 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein COR PF16095.5 KXZ42703.1 - 1.2e-40 139.5 0.0 3.8e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain Roc PF08477.13 KXZ42703.1 - 9.2e-15 54.9 0.0 1.8e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ42703.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXZ42703.1 - 1.7e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ras family DUF1011 PF06237.12 KXZ42703.1 - 0.0087 16.4 0.2 6.7 7.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1011) AAA_25 PF13481.6 KXZ42703.1 - 0.025 14.2 0.1 0.1 12.2 0.1 2.1 1 0 0 1 1 1 0 AAA domain DUF3969 PF13108.6 KXZ42703.1 - 0.033 14.2 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) AAA_22 PF13401.6 KXZ42703.1 - 0.099 12.9 0.0 0.84 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Lar_restr_allev PF14354.6 KXZ42703.1 - 0.15 12.4 0.2 0.42 11.0 0.2 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF1805 PF08827.11 KXZ42703.1 - 0.16 12.4 0.6 9.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Mg_chelatase PF01078.21 KXZ42703.1 - 0.18 11.2 0.5 0.31 10.4 0.5 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ42703.1 - 0.23 11.9 1.3 2.2 8.7 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain Pkinase PF00069.25 KXZ42704.1 - 1.4e-07 31.1 0.0 7.5e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42704.1 - 4.5e-07 29.4 0.0 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4231 PF14015.6 KXZ42704.1 - 0.47 10.9 2.1 18 5.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Gram_pos_anchor PF00746.21 KXZ42704.1 - 1.3 9.1 3.6 0.74 9.8 0.3 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Pkinase PF00069.25 KXZ42705.1 - 8.4e-15 54.8 0.0 1.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42705.1 - 4.8e-12 45.7 0.0 4.3e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ42706.1 - 1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42706.1 - 5.2e-07 29.2 0.0 2.1e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Mcl1_mid PF12341.8 KXZ42707.1 - 6.6e-22 78.2 0.0 1.2e-21 77.3 0.0 1.4 1 1 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KXZ42707.1 - 2.1e-10 41.0 0.0 0.017 16.0 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ42707.1 - 1.1e-06 28.8 0.0 0.011 16.0 0.0 3.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ42707.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.17 KXZ42708.1 - 0.00069 19.5 3.2 0.53 10.5 0.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ42708.1 - 0.0021 18.6 6.9 0.16 12.7 1.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ42708.1 - 0.036 14.6 2.5 0.036 14.6 2.5 5.2 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42708.1 - 0.067 14.0 18.7 5.1 8.2 4.4 6.5 4 2 1 5 5 5 0 Tetratricopeptide repeat DUF1818 PF08848.11 KXZ42709.1 - 0.082 13.0 0.3 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) RPN13_C PF16550.5 KXZ42709.1 - 0.13 12.4 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 UCH-binding domain TPR_14 PF13428.6 KXZ42712.1 - 2.6e-09 37.1 9.6 1.4e-05 25.5 0.8 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ42712.1 - 5.2e-07 29.3 4.6 0.00061 19.7 0.3 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ42712.1 - 2.8e-06 27.9 8.0 0.00086 19.9 2.7 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ42712.1 - 9.9e-05 22.0 0.5 0.038 13.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ42712.1 - 0.00025 21.5 5.1 0.12 12.9 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ42712.1 - 0.00028 21.1 0.2 1.1 9.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ42712.1 - 0.00031 20.8 4.6 0.01 15.9 0.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ42712.1 - 0.0015 19.0 4.4 0.29 11.9 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ42712.1 - 0.002 18.2 0.9 0.025 14.7 0.1 2.7 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF2625 PF10946.8 KXZ42712.1 - 0.038 13.1 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 TPR_12 PF13424.6 KXZ42712.1 - 0.078 13.3 2.9 0.17 12.2 0.7 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 KXZ42712.1 - 0.3 11.4 0.8 15 6.1 0.1 2.9 2 1 1 3 3 3 0 PPR repeat FmdA_AmdA PF03069.15 KXZ42713.1 - 3.5e-46 157.8 0.0 4.1e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family FmdA_AmdA PF03069.15 KXZ42714.1 - 1.4e-20 73.6 0.2 1.4e-20 73.5 0.2 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Flavin_Reduct PF01613.18 KXZ42715.1 - 5.1e-14 52.6 0.0 2.2e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 Flavin reductase like domain Lactamase_B_2 PF12706.7 KXZ42715.1 - 0.04 13.4 0.1 0.093 12.2 0.1 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF5408 PF17402.2 KXZ42716.1 - 0.046 13.6 5.0 8.4 6.4 0.2 3.4 1 1 3 4 4 4 0 Family of unknown function (DUF5408) TcdA_TcdB_pore PF12920.7 KXZ42716.1 - 0.52 8.5 4.4 0.57 8.4 4.4 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain NPV_P10 PF05531.12 KXZ42716.1 - 0.85 10.1 4.4 2.3 8.7 1.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Lactamase_B PF00753.27 KXZ42718.1 - 5e-08 33.2 0.1 1.6e-07 31.6 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXZ42718.1 - 0.0023 17.5 0.0 0.0043 16.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Flavin_Reduct PF01613.18 KXZ42718.1 - 0.033 14.2 0.2 0.065 13.3 0.2 1.5 1 0 0 1 1 1 0 Flavin reductase like domain HlyIII PF03006.20 KXZ42719.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Haemolysin-III related TPR_2 PF07719.17 KXZ42721.1 - 2.4e-11 42.8 3.9 8.8e-06 25.5 0.2 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ42721.1 - 8.3e-09 35.0 0.8 0.0028 17.7 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ42721.1 - 1.3e-08 34.4 1.4 0.0029 17.3 0.1 3.7 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 KXZ42721.1 - 5.5e-08 32.3 0.4 0.004 16.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ42721.1 - 7.2e-07 29.8 0.9 7.2e-07 29.8 0.9 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ42721.1 - 2.3e-05 24.5 0.7 0.0054 16.9 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXZ42721.1 - 5.2e-05 23.7 1.1 5.2e-05 23.7 1.1 5.8 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ42721.1 - 5.7e-05 22.5 5.1 0.00023 20.5 1.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ42721.1 - 0.0033 17.5 11.8 0.023 14.8 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ42721.1 - 0.0058 17.1 0.2 0.0058 17.1 0.2 4.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ42721.1 - 0.043 13.8 3.3 1.7 8.8 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ42721.1 - 0.056 13.7 19.0 0.18 12.1 0.6 4.4 4 2 0 4 4 3 0 Tetratricopeptide repeat YfiO PF13525.6 KXZ42721.1 - 0.068 12.9 0.3 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein HrpB1_HrpK PF09613.10 KXZ42721.1 - 0.076 12.6 3.5 3.1 7.5 0.1 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Cwf_Cwc_15 PF04889.12 KXZ42721.1 - 0.19 11.4 4.6 0.29 10.8 4.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_6 PF13174.6 KXZ42721.1 - 0.71 10.6 18.8 0.31 11.8 0.4 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 KXZ42721.1 - 2.4 6.2 8.1 3.2 5.7 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DNA_pol_B_exo2 PF10108.9 KXZ42722.1 - 0.033 13.9 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Guanylate_cyc PF00211.20 KXZ42723.1 - 1.3e-49 168.3 0.0 1.9e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain UDPGP PF01704.18 KXZ42725.1 - 1.8e-06 26.9 0.0 2.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Adeno_terminal PF02459.15 KXZ42725.1 - 1.8 6.8 2.8 2.5 6.4 2.8 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Herpes_IE68 PF02479.16 KXZ42726.1 - 0.071 12.7 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus immediate early protein HWE_HK PF07536.14 KXZ42729.1 - 0.18 12.5 0.0 0.5 11.1 0.0 1.8 2 0 0 2 2 2 0 HWE histidine kinase Amidase PF01425.21 KXZ42730.1 - 2.3e-20 73.0 0.0 3.6e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Amidase Pkinase_Tyr PF07714.17 KXZ42732.1 - 1.3e-28 100.0 0.0 4.3e-24 85.2 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ42732.1 - 4.8e-26 91.7 0.0 1.9e-24 86.4 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ42732.1 - 0.0046 16.3 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ42732.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXZ42732.1 - 0.18 10.5 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 KXZ42733.1 - 0.00066 20.2 0.0 0.01 16.4 0.0 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42733.1 - 0.0027 18.0 0.1 0.61 10.8 0.0 3.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXZ42733.1 - 0.027 14.8 0.1 4.3 7.8 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42733.1 - 0.065 13.7 0.2 3.5 8.2 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat HSP70 PF00012.20 KXZ42734.1 - 1e-264 879.3 14.3 1.2e-264 879.1 14.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ42734.1 - 7.5e-18 64.4 1.3 1.6e-16 60.1 0.2 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KXZ42734.1 - 8.5e-05 22.9 6.4 0.13 12.6 0.1 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Enolase_N PF03952.16 KXZ42734.1 - 0.022 14.9 4.1 1.1 9.5 0.1 2.8 2 1 0 2 2 2 0 Enolase, N-terminal domain Hydantoinase_A PF01968.18 KXZ42734.1 - 0.049 12.9 6.5 0.061 12.6 0.2 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KXZ42734.1 - 0.11 12.2 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FANCI_S3 PF14677.6 KXZ42734.1 - 0.12 12.1 0.4 0.24 11.1 0.4 1.4 1 0 0 1 1 1 0 FANCI solenoid 3 DIOX_N PF14226.6 KXZ42734.1 - 0.17 12.6 2.5 0.44 11.3 1.3 2.3 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal DDR PF08841.10 KXZ42734.1 - 0.2 10.6 4.6 0.16 11.0 0.2 2.5 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Radial_spoke_3 PF06098.11 KXZ42734.1 - 0.67 9.2 11.1 0.02 14.2 4.5 1.8 2 0 0 2 2 2 0 Radial spoke protein 3 HSP90 PF00183.18 KXZ42735.1 - 8.8e-200 665.0 25.2 1.2e-199 664.6 25.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KXZ42735.1 - 7.2e-11 42.6 0.1 1.3e-10 41.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXZ42735.1 - 7.2e-09 35.6 0.9 3.3e-08 33.5 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hom_end PF05204.14 KXZ42735.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Homing endonuclease DUF134 PF02001.16 KXZ42735.1 - 0.12 12.9 1.1 8.1 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF134 HSP70 PF00012.20 KXZ42736.1 - 3.5e-33 114.7 0.2 4e-33 114.5 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 KXZ42737.1 - 1.8e-134 449.2 0.6 2.1e-134 449.0 0.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ42737.1 - 6e-07 28.6 0.0 8.5e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 KXZ42737.1 - 0.1 11.8 0.1 0.24 10.6 0.1 1.6 1 1 1 2 2 2 0 StbA protein FGGY_C PF02782.16 KXZ42737.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain GRAM PF02893.20 KXZ42738.1 - 4.5e-09 36.2 0.0 6.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 GRAM domain MCR_alpha PF02249.17 KXZ42738.1 - 0.001 19.5 2.0 0.0011 19.4 0.1 1.9 2 0 0 2 2 2 1 Methyl-coenzyme M reductase alpha subunit, C-terminal domain SOG2 PF10428.9 KXZ42738.1 - 0.14 11.3 5.6 0.2 10.8 5.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KXZ42738.1 - 1.2 7.8 4.7 1.3 7.6 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 KXZ42738.1 - 6.6 6.6 8.0 11 5.8 8.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Redoxin PF08534.10 KXZ42739.1 - 1.2e-07 31.6 0.0 1.3e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin EccE PF11203.8 KXZ42739.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Pro_isomerase PF00160.21 KXZ42740.1 - 0.0072 16.6 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAD_binding_7 PF03441.14 KXZ42741.1 - 8.7e-58 195.1 0.1 1.1e-57 194.8 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Transketolase_N PF00456.21 KXZ42742.1 - 6.4e-157 521.7 0.0 8.7e-157 521.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXZ42742.1 - 5.3e-44 150.0 0.1 1.1e-43 149.0 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXZ42742.1 - 1.7e-13 50.5 0.0 4.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KXZ42742.1 - 3.1e-05 23.3 0.0 0.002 17.4 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase YGGT PF02325.17 KXZ42743.1 - 6.1e-14 52.2 5.0 6.1e-14 52.2 5.0 1.7 2 0 0 2 2 2 1 YGGT family Adeno_E3B PF03376.14 KXZ42743.1 - 0.66 10.3 4.5 1.3 9.3 0.0 2.8 3 1 0 3 3 3 0 Adenovirus E3B protein MID_MedPIWI PF18296.1 KXZ42744.1 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 MID domain of medPIWI zf-UBP_var PF17807.1 KXZ42745.1 - 2.8e-23 81.4 0.0 4.8e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Variant UBP zinc finger UCH PF00443.29 KXZ42745.1 - 2.8e-16 59.8 0.0 4.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA_2 PF07724.14 KXZ42746.1 - 1.9e-55 187.6 0.0 5e-52 176.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXZ42746.1 - 1.6e-34 117.9 1.0 4.8e-34 116.4 1.0 1.8 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 KXZ42746.1 - 9.1e-26 90.8 0.0 1.7e-13 51.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXZ42746.1 - 8.6e-20 70.6 0.0 7.7e-19 67.5 0.0 2.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXZ42746.1 - 1.5e-18 67.1 0.1 2.9e-13 50.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ42746.1 - 2.7e-13 50.7 14.8 6.7e-07 29.8 0.3 5.5 4 2 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 KXZ42746.1 - 2e-09 37.8 3.9 0.0021 18.3 0.0 4.6 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KXZ42746.1 - 2.2e-09 37.3 0.0 4.7e-07 29.7 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXZ42746.1 - 2.1e-07 30.9 0.0 0.0093 15.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KXZ42746.1 - 1.6e-06 28.2 0.0 0.032 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KXZ42746.1 - 2.7e-06 27.5 0.0 0.85 9.5 0.0 3.7 3 1 1 4 4 4 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KXZ42746.1 - 3.1e-06 26.8 0.0 0.023 14.2 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXZ42746.1 - 5.3e-06 26.0 0.1 0.034 13.5 0.1 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXZ42746.1 - 1.1e-05 25.7 0.5 0.12 12.6 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KXZ42746.1 - 1.2e-05 25.9 0.2 0.057 13.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KXZ42746.1 - 4e-05 24.2 0.5 0.14 12.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain Clp_N PF02861.20 KXZ42746.1 - 5.1e-05 23.3 2.9 0.0013 18.8 1.1 3.4 3 0 0 3 3 2 1 Clp amino terminal domain, pathogenicity island component NACHT PF05729.12 KXZ42746.1 - 5.7e-05 23.1 0.0 0.095 12.6 0.0 2.8 2 1 0 2 2 2 2 NACHT domain Roc PF08477.13 KXZ42746.1 - 0.00023 21.3 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KXZ42746.1 - 0.00028 20.2 0.6 0.23 10.6 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXZ42746.1 - 0.00033 21.0 0.1 0.93 9.9 0.0 2.8 3 0 0 3 3 2 1 RNA helicase RuvB_N PF05496.12 KXZ42746.1 - 0.00035 20.4 1.4 0.64 9.8 0.0 4.1 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KXZ42746.1 - 0.00041 20.3 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXZ42746.1 - 0.00043 20.5 0.0 0.74 10.0 0.0 3.4 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KXZ42746.1 - 0.00043 20.2 0.0 0.43 10.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXZ42746.1 - 0.00054 19.6 0.2 0.12 11.9 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXZ42746.1 - 0.0008 19.2 0.0 0.59 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KXZ42746.1 - 0.00086 19.2 0.1 0.62 9.9 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KXZ42746.1 - 0.0011 19.5 0.0 0.14 12.6 0.0 2.7 2 0 0 2 2 2 1 ABC transporter TniB PF05621.11 KXZ42746.1 - 0.0017 17.8 0.1 4.1 6.8 0.1 3.5 2 1 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 KXZ42746.1 - 0.0024 17.6 0.0 0.91 9.3 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KXZ42746.1 - 0.0024 17.6 0.3 2.9 7.6 0.0 3.6 3 2 0 3 3 3 1 AAA domain DNA_pol3_delta2 PF13177.6 KXZ42746.1 - 0.0086 15.9 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Zeta_toxin PF06414.12 KXZ42746.1 - 0.0089 15.3 0.0 0.51 9.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 KXZ42746.1 - 0.011 16.0 0.4 0.94 9.8 0.1 3.0 3 1 0 3 3 2 0 AAA domain ResIII PF04851.15 KXZ42746.1 - 0.018 15.0 0.0 0.5 10.3 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 KXZ42746.1 - 0.019 14.2 0.3 2.8 7.1 0.0 2.6 3 0 0 3 3 3 0 TIP49 P-loop domain T2SSE PF00437.20 KXZ42746.1 - 0.025 13.7 0.0 0.069 12.2 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 KXZ42746.1 - 0.027 14.4 0.2 5.3 6.9 0.0 2.8 3 0 0 3 3 2 0 NTPase DUF3535 PF12054.8 KXZ42746.1 - 0.029 13.6 0.6 0.064 12.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) SRP54 PF00448.22 KXZ42746.1 - 0.038 13.6 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 KXZ42746.1 - 0.053 13.6 0.6 0.76 9.8 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 KXZ42746.1 - 0.12 12.1 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.23 KXZ42746.1 - 0.15 12.2 0.0 4.9 7.2 0.0 2.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_8 PF12780.7 KXZ42746.1 - 0.15 11.4 0.2 1.6 8.0 0.1 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 Guanylate_cyc PF00211.20 KXZ42747.1 - 1.7e-08 34.3 0.1 0.083 12.5 0.0 3.2 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain Myb_DNA-binding PF00249.31 KXZ42748.1 - 2.7e-22 78.7 6.7 5.8e-11 42.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ42748.1 - 6e-15 55.2 0.1 7.4e-08 32.5 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXZ42748.1 - 0.034 14.5 3.0 1.2 9.5 0.1 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain O-FucT PF10250.9 KXZ42749.1 - 1.1e-07 31.9 0.0 0.0081 15.9 0.0 3.2 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Glyco_transf_8 PF01501.20 KXZ42749.1 - 0.083 12.4 1.3 0.88 9.1 0.0 2.1 1 1 1 2 2 2 0 Glycosyl transferase family 8 RETICULATA-like PF11891.8 KXZ42750.1 - 3.5e-60 202.8 0.0 1e-59 201.3 0.0 1.7 2 0 0 2 2 2 1 Protein RETICULATA-related GRA6 PF05084.13 KXZ42750.1 - 3.2 7.6 9.9 6.4 6.7 9.9 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) TFIIA PF03153.13 KXZ42751.1 - 4.9 7.0 21.0 4.9 7.0 4.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit QRPTase_C PF01729.19 KXZ42752.1 - 1.3e-46 158.4 1.4 3.8e-46 156.9 1.4 1.7 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KXZ42752.1 - 2.4e-26 91.6 0.0 6.4e-26 90.2 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl_2 PF13533.6 KXZ42752.1 - 0.059 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like PP2C PF00481.21 KXZ42753.1 - 3.6e-50 171.0 0.2 2.1e-48 165.2 0.1 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXZ42753.1 - 4.9e-05 23.1 2.1 0.00011 21.9 2.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C IQ PF00612.27 KXZ42754.1 - 0.0072 16.0 0.6 0.061 13.1 0.6 2.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Streptin-Immun PF11083.8 KXZ42754.1 - 0.028 14.8 2.1 0.028 14.8 2.1 2.2 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein GST_C_3 PF14497.6 KXZ42755.1 - 7e-18 64.7 0.1 1.1e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXZ42755.1 - 0.00073 19.7 0.1 0.0012 19.0 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ42755.1 - 0.033 14.2 0.8 0.21 11.6 0.2 2.7 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain TMEM18 PF14770.6 KXZ42756.1 - 1.4e-29 102.5 1.0 1.6e-29 102.3 1.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 Babuvirus_MP PF07234.11 KXZ42756.1 - 0.022 14.9 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Movement and RNA silencing protein HemY_N PF07219.13 KXZ42756.1 - 0.023 14.9 0.1 0.058 13.6 0.0 1.6 2 0 0 2 2 2 0 HemY protein N-terminus Protocadherin PF08374.11 KXZ42756.1 - 0.04 13.9 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Protocadherin UQ_con PF00179.26 KXZ42757.1 - 1.5e-19 70.0 1.4 3.2e-14 52.8 0.3 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme CRAL_TRIO PF00650.20 KXZ42758.1 - 2e-32 112.1 0.0 2.4e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain EMP24_GP25L PF01105.24 KXZ42759.1 - 1.2e-22 80.7 0.0 1.6e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 KXZ42761.1 - 5.5e-51 173.5 0.0 8e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42761.1 - 1.2e-24 87.0 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ42761.1 - 4.1e-08 32.9 0.0 6.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ42761.1 - 0.0041 16.0 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ42761.1 - 7.6 6.4 14.8 0.041 13.8 1.7 3.1 3 1 1 4 4 4 0 Phosphotransferase enzyme family p25-alpha PF05517.12 KXZ42762.1 - 4.5e-11 43.1 0.0 0.0011 19.2 0.0 3.5 3 0 0 3 3 3 3 p25-alpha EF-hand_6 PF13405.6 KXZ42762.1 - 2.3e-05 23.9 1.9 0.00049 19.8 0.6 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KXZ42762.1 - 2.4e-05 23.5 1.0 0.0013 18.1 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXZ42762.1 - 3.8e-05 24.0 0.9 0.045 14.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXZ42762.1 - 0.37 10.7 1.5 4.8 7.1 0.5 2.5 2 0 0 2 2 2 0 EF-hand domain pair ATG16 PF08614.11 KXZ42762.1 - 0.55 10.4 15.0 0.017 15.3 3.4 2.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KXZ42762.1 - 5.7 5.7 8.4 1.5 7.6 3.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Pkinase PF00069.25 KXZ42763.1 - 3.3e-28 98.8 0.0 7.7e-28 97.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42763.1 - 5.9e-27 94.6 0.0 9.2e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase NUDIX PF00293.28 KXZ42763.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Bud13 PF09736.9 KXZ42765.1 - 4.8e-33 114.6 2.8 4.8e-33 114.6 2.8 3.1 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF2203 PF09969.9 KXZ42765.1 - 0.94 10.2 6.7 1.7 9.4 5.6 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) hnRNP_Q_AcD PF18360.1 KXZ42766.1 - 1.5e-20 72.9 0.0 6.5e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain DnaJ PF00226.31 KXZ42767.1 - 5.1e-19 68.2 0.8 3.5e-18 65.5 0.3 2.7 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 KXZ42767.1 - 8.7e-15 54.7 0.7 2e-07 31.1 0.1 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ42767.1 - 1.5e-05 25.1 0.8 0.0084 16.3 0.1 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 KXZ42767.1 - 0.15 12.4 0.0 0.15 12.4 0.0 4.2 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ApoO PF09769.9 KXZ42767.1 - 1.5 8.7 4.8 22 5.0 0.7 3.1 3 0 0 3 3 3 0 Apolipoprotein O Sec8_exocyst PF04048.14 KXZ42768.1 - 3.2e-19 69.2 0.0 1.3e-18 67.2 0.1 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KXZ42768.1 - 1.3e-07 31.2 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec5 PF15469.6 KXZ42768.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 IFT57 PF10498.9 KXZ42768.1 - 0.11 11.5 0.2 0.17 10.8 0.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DnaJ PF00226.31 KXZ42769.1 - 2.2e-18 66.1 0.0 3.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain CS PF04969.16 KXZ42769.1 - 0.0002 22.3 0.0 0.14 13.2 0.0 2.5 2 1 0 2 2 2 2 CS domain zf-B_box PF00643.24 KXZ42769.1 - 0.0025 17.9 4.3 0.0025 17.9 4.3 1.8 2 0 0 2 2 2 1 B-box zinc finger C5HCH PF17982.1 KXZ42769.1 - 0.32 11.2 6.4 0.78 9.9 6.4 1.6 1 0 0 1 1 1 0 NSD Cys-His rich domain zf-HIT PF04438.16 KXZ42769.1 - 3.5 7.6 7.9 7.7 6.5 7.9 1.6 1 0 0 1 1 1 0 HIT zinc finger GFO_IDH_MocA PF01408.22 KXZ42771.1 - 8.8e-25 87.9 0.0 1.7e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Auto_anti-p27 PF06677.12 KXZ42773.1 - 2.1e-15 56.6 6.6 1.1e-14 54.3 1.2 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KXZ42773.1 - 0.0067 16.4 1.5 0.16 12.0 0.3 2.3 2 0 0 2 2 2 1 Double zinc ribbon Lar_restr_allev PF14354.6 KXZ42773.1 - 0.049 14.0 1.7 0.19 12.2 1.7 2.0 1 0 0 1 1 1 0 Restriction alleviation protein Lar PocR PF10114.9 KXZ42773.1 - 0.21 11.4 0.1 22 4.8 0.0 2.3 2 0 0 2 2 2 0 Sensory domain found in PocR IBR PF01485.21 KXZ42773.1 - 0.21 11.8 1.5 0.68 10.2 0.4 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 KXZ42773.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.0 2 1 0 3 3 3 0 zinc-ribbon zinc-ribbons_6 PF07191.12 KXZ42773.1 - 0.45 10.5 2.6 0.44 10.6 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbons Peptidase_C1 PF00112.23 KXZ42774.1 - 1.4e-21 77.6 0.0 2.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease EccE PF11203.8 KXZ42774.1 - 0.0016 18.7 0.2 0.0041 17.4 0.0 1.8 2 0 0 2 2 2 1 Putative type VII ESX secretion system translocon, EccE Pilus_CpaD PF09476.10 KXZ42774.1 - 0.047 13.4 0.2 0.078 12.7 0.2 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) NOA36 PF06524.12 KXZ42775.1 - 3 7.1 11.3 3.5 6.9 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein Cnd2 PF05786.14 KXZ42775.1 - 4.4 5.8 6.1 5.5 5.5 6.1 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 SDA1 PF05285.12 KXZ42775.1 - 5.6 6.3 11.2 6.4 6.1 11.2 1.0 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.8 KXZ42775.1 - 6.7 6.9 14.9 7.8 6.7 14.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KXZ42775.1 - 8.6 4.4 11.2 8.8 4.4 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.16 KXZ42776.1 - 0.0022 17.0 14.3 0.0022 17.0 14.3 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5392 PF17370.2 KXZ42776.1 - 0.07 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5392) zf-MYND PF01753.18 KXZ42777.1 - 9.4e-05 22.4 7.2 9.4e-05 22.4 7.2 1.9 2 0 0 2 2 2 1 MYND finger DUF5635 PF18685.1 KXZ42777.1 - 0.045 13.7 0.9 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5635) Acetyltransf_6 PF13480.7 KXZ42777.1 - 3.4 7.8 6.9 2.1 8.5 1.9 2.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Yip1 PF04893.17 KXZ42778.1 - 5.8e-05 22.9 7.2 7e-05 22.6 7.2 1.1 1 0 0 1 1 1 1 Yip1 domain Na_H_Exchanger PF00999.21 KXZ42779.1 - 1.3e-31 109.8 28.8 1.7e-31 109.4 26.7 1.8 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Syja_N PF02383.18 KXZ42780.1 - 3.4e-05 23.3 0.0 3.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain HYR PF02494.16 KXZ42781.1 - 2.3e-12 47.1 12.6 9e-07 29.1 0.7 4.6 3 1 1 4 4 4 3 HYR domain Jacalin PF01419.17 KXZ42781.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain AltA1 PF16541.5 KXZ42781.1 - 0.02 15.8 1.5 2 9.3 0.0 3.1 3 0 0 3 3 3 0 Alternaria alternata allergen 1 DUF11 PF01345.18 KXZ42781.1 - 0.083 13.2 12.3 0.1 12.9 0.6 4.4 4 3 0 4 4 4 0 Domain of unknown function DUF11 EGF_3 PF12947.7 KXZ42782.1 - 3.1e-10 40.1 54.5 0.016 15.4 4.0 8.0 7 0 0 7 7 7 6 EGF domain cEGF PF12662.7 KXZ42782.1 - 0.00013 21.8 51.6 0.013 15.4 5.5 7.6 7 0 0 7 7 7 4 Complement Clr-like EGF-like EGF PF00008.27 KXZ42782.1 - 0.083 13.2 0.4 0.083 13.2 0.4 10.0 9 2 0 9 9 9 0 EGF-like domain hEGF PF12661.7 KXZ42782.1 - 0.12 13.0 0.5 0.12 13.0 0.5 9.0 8 0 0 8 8 8 0 Human growth factor-like EGF RANK_CRD_2 PF18278.1 KXZ42782.1 - 1.1 9.5 35.0 1.4 9.2 0.6 6.7 7 0 0 7 7 7 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 FXa_inhibition PF14670.6 KXZ42782.1 - 1.9 8.9 77.3 0.04 14.2 5.0 8.3 8 0 0 8 8 8 0 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KXZ42782.1 - 9.2 6.7 52.9 0.23 11.8 2.5 7.2 6 1 0 6 6 6 0 Pvs28 EGF domain DUF3878 PF12994.7 KXZ42784.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) Chromo PF00385.24 KXZ42785.1 - 2e-09 37.2 0.1 2.9e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4922 PF16269.5 KXZ42785.1 - 0.18 11.6 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) FAM176 PF14851.6 KXZ42791.1 - 0.14 11.8 0.3 0.28 10.8 0.3 1.4 1 0 0 1 1 1 0 FAM176 family HNH_3 PF13392.6 KXZ42792.1 - 4.3e-05 23.2 0.1 8.2e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Glyoxalase PF00903.25 KXZ42793.1 - 0.066 13.4 0.1 4.4 7.5 0.0 2.6 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Myc_N PF01056.18 KXZ42793.1 - 0.13 12.1 4.8 0.19 11.6 4.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Na_trans_assoc PF06512.13 KXZ42793.1 - 0.19 12.0 5.4 0.31 11.3 5.4 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DNA_pol_phi PF04931.13 KXZ42793.1 - 0.46 8.5 10.1 0.66 8.0 10.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KXZ42793.1 - 1.1 7.4 12.5 1.6 6.9 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KXZ42793.1 - 1.8 7.8 10.2 1.2 8.4 8.6 1.4 1 1 0 1 1 1 0 NOA36 protein DUF4820 PF16091.5 KXZ42793.1 - 2.2 7.6 4.9 3.7 6.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF5523 PF17661.1 KXZ42793.1 - 2.6 7.7 10.9 4.1 7.0 10.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) PPP4R2 PF09184.11 KXZ42793.1 - 7.7 6.0 11.9 12 5.4 11.9 1.2 1 0 0 1 1 1 0 PPP4R2 HYR PF02494.16 KXZ42794.1 - 3.2e-12 46.6 19.2 0.0006 20.1 0.1 5.4 6 0 0 6 6 6 4 HYR domain RicinB_lectin_2 PF14200.6 KXZ42794.1 - 2.2e-05 25.1 0.0 8.4e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like EGF_CA PF07645.15 KXZ42794.1 - 0.73 10.1 4.7 2.5 8.4 4.7 2.0 1 0 0 1 1 1 0 Calcium-binding EGF domain SlyX PF04102.12 KXZ42795.1 - 0.0032 18.0 2.0 0.067 13.8 0.2 2.6 2 0 0 2 2 2 1 SlyX Uso1_p115_C PF04871.13 KXZ42795.1 - 0.09 13.1 2.9 0.12 12.8 1.5 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Seryl_tRNA_N PF02403.22 KXZ42795.1 - 0.77 10.0 7.6 0.4 10.9 3.8 2.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Nup188 PF10487.9 KXZ42796.1 - 0.38 8.6 0.0 5.8 4.7 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin subcomplex protein binding to Pom34 COG6 PF06419.11 KXZ42797.1 - 3.6e-137 458.3 0.0 4.2e-137 458.0 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 AurF PF11583.8 KXZ42797.1 - 0.018 14.4 0.5 0.43 9.8 0.1 2.2 2 0 0 2 2 2 0 P-aminobenzoate N-oxygenase AurF Bep_C_terminal PF17841.1 KXZ42797.1 - 0.032 14.4 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) Thioredoxin PF00085.20 KXZ42798.1 - 2.2e-27 95.0 0.1 2.5e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KXZ42798.1 - 1.2e-05 25.1 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KXZ42798.1 - 1.8e-05 24.9 0.2 4e-05 23.7 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KXZ42798.1 - 3.9e-05 23.9 0.0 0.00038 20.7 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXZ42798.1 - 9.2e-05 22.9 0.2 0.0031 17.9 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Phosducin PF02114.16 KXZ42798.1 - 0.0025 16.8 0.0 0.0027 16.7 0.0 1.0 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.21 KXZ42798.1 - 0.0044 16.9 0.1 0.017 15.1 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KXZ42798.1 - 0.005 16.2 0.0 0.0057 16.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KXZ42798.1 - 0.085 12.6 0.2 0.27 10.9 0.2 1.7 1 1 0 1 1 1 0 Redoxin DUF834 PF05754.14 KXZ42798.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF834) COG6 PF06419.11 KXZ42799.1 - 1.4e-35 122.6 0.0 1.7e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Hint PF01079.20 KXZ42801.1 - 2.1e-14 53.5 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.11 KXZ42801.1 - 0.005 17.1 0.0 0.013 15.8 0.0 1.6 2 0 0 2 2 2 1 Pretoxin HINT domain EF-hand_5 PF13202.6 KXZ42801.1 - 0.021 14.3 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ42801.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KXZ42801.1 - 0.085 12.4 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 EF hand HPP PF04982.13 KXZ42802.1 - 3.8e-23 82.0 8.6 3.8e-23 82.0 8.6 1.7 2 0 0 2 2 2 1 HPP family Chloroa_b-bind PF00504.21 KXZ42803.1 - 9.3e-40 136.8 0.0 1.2e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RRM_1 PF00076.22 KXZ42804.1 - 1.3e-17 63.4 0.0 1.8e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ42804.1 - 0.1 12.7 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif tRNA_bind PF01588.20 KXZ42805.1 - 2e-33 114.4 0.1 3.1e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Glu-tRNAGln PF02686.15 KXZ42805.1 - 5.3e-16 58.6 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Med3 PF11593.8 KXZ42805.1 - 9.8 5.2 9.2 14 4.7 9.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HECT PF00632.25 KXZ42806.1 - 2.6e-71 240.6 0.0 8.3e-69 232.4 0.0 2.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 KXZ42807.1 - 2.1e-42 145.7 0.0 2.7e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 KXZ42807.1 - 9.2e-17 61.4 23.8 7.5e-07 29.7 1.0 5.3 4 2 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ42807.1 - 2.6e-13 49.4 20.3 4.6e-07 29.5 1.6 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DUF4231 PF14015.6 KXZ42807.1 - 0.45 11.0 4.3 1.7 9.2 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) tRNA-Thr_ED PF08915.11 KXZ42811.1 - 0.26 11.3 0.0 0.46 10.6 0.0 1.3 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Ank_2 PF12796.7 KXZ42812.1 - 1e-14 54.9 0.5 1.7e-06 28.5 0.4 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42812.1 - 9.2e-12 45.2 0.5 2.7e-05 24.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ42812.1 - 3.7e-10 39.9 0.2 2e-05 24.8 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42812.1 - 3.7e-09 36.1 0.9 0.014 15.9 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KXZ42812.1 - 3.8e-08 33.4 0.6 0.013 15.9 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXZ42813.1 - 5.1e-08 33.4 0.4 0.93 10.1 0.0 5.4 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42813.1 - 5.5e-08 33.2 4.2 2.6 8.7 0.0 6.6 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42813.1 - 5.9e-05 23.2 2.2 25 5.8 0.0 7.0 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ42813.1 - 0.002 18.4 1.4 7.6 7.0 0.3 4.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Cupin_8 PF13621.6 KXZ42814.1 - 9.5e-20 71.4 0.0 1.3e-18 67.6 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXZ42814.1 - 2.6e-18 66.5 0.0 4.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase SR-25 PF10500.9 KXZ42814.1 - 0.0044 16.6 13.6 0.0044 16.6 13.6 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein PIP5K PF01504.18 KXZ42815.1 - 9.9e-62 208.6 0.0 1.3e-60 204.9 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 KXZ42815.1 - 4.8e-21 73.3 28.2 2.1e-06 27.3 4.6 5.5 5 0 0 5 5 5 4 MORN repeat Ank_2 PF12796.7 KXZ42816.1 - 8.1e-45 151.3 7.0 9.4e-14 51.8 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42816.1 - 2.5e-32 110.8 3.9 5e-12 46.1 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42816.1 - 2.7e-32 107.2 7.9 8.5e-07 28.8 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KXZ42816.1 - 1.6e-31 107.3 11.9 6.3e-06 26.4 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXZ42816.1 - 1.6e-27 95.2 9.4 1.2e-08 35.0 0.1 5.3 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Tim54 PF11711.8 KXZ42816.1 - 0.00052 18.9 0.9 0.00067 18.5 0.9 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.12 KXZ42816.1 - 0.0028 17.1 13.0 0.0035 16.8 13.0 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 KXZ42816.1 - 0.018 14.4 10.5 0.025 13.9 10.5 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KXZ42816.1 - 0.019 13.1 23.0 0.022 12.9 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 KXZ42816.1 - 0.027 14.7 14.1 0.048 13.9 14.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated THOC2_N PF16134.5 KXZ42816.1 - 0.03 13.0 3.6 0.047 12.3 3.6 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus CobT PF06213.12 KXZ42816.1 - 0.041 13.3 15.0 0.061 12.7 15.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Toprim_3 PF13362.6 KXZ42816.1 - 0.073 13.4 0.8 0.17 12.3 0.8 1.5 1 0 0 1 1 1 0 Toprim domain Zip PF02535.22 KXZ42816.1 - 0.081 12.1 0.9 0.09 12.0 0.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4366 PF14283.6 KXZ42816.1 - 0.083 12.9 5.0 0.16 12.0 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4471 PF14740.6 KXZ42816.1 - 0.099 11.9 2.8 0.14 11.4 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) RNase_H2_suC PF08615.11 KXZ42816.1 - 0.11 12.7 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DARPP-32 PF05395.12 KXZ42816.1 - 0.11 12.7 14.6 0.15 12.3 14.6 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 SpoIIP PF07454.11 KXZ42816.1 - 0.13 11.7 5.6 0.2 11.1 5.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Prothymosin PF03247.14 KXZ42816.1 - 0.14 12.7 33.3 0.24 11.9 33.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nop14 PF04147.12 KXZ42816.1 - 0.14 10.4 18.3 0.17 10.1 18.3 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 KXZ42816.1 - 0.15 11.2 10.7 0.19 10.9 10.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit EIIBC-GUT_N PF03612.14 KXZ42816.1 - 0.21 11.3 3.4 0.43 10.3 3.4 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Mpp10 PF04006.12 KXZ42816.1 - 0.27 9.7 19.3 0.35 9.3 19.3 1.1 1 0 0 1 1 1 0 Mpp10 protein MRNIP PF15749.5 KXZ42816.1 - 0.29 11.9 4.4 0.44 11.3 4.4 1.2 1 0 0 1 1 1 0 MRN-interacting protein Pox_Ag35 PF03286.14 KXZ42816.1 - 0.3 10.8 14.1 0.48 10.2 14.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 KXZ42816.1 - 0.32 11.0 9.6 0.54 10.3 9.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FYDLN_acid PF09538.10 KXZ42816.1 - 0.34 11.6 14.2 0.55 10.9 14.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CPSF100_C PF13299.6 KXZ42816.1 - 0.36 11.0 6.4 0.56 10.4 6.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFB6 PF17110.5 KXZ42816.1 - 0.38 10.5 9.9 0.64 9.7 9.9 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NPR3 PF03666.13 KXZ42816.1 - 0.62 8.8 2.4 0.73 8.6 2.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2722 PF10846.8 KXZ42816.1 - 0.69 8.8 5.5 0.88 8.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4045 PF13254.6 KXZ42816.1 - 0.77 9.3 4.4 0.93 9.1 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Sigma70_ner PF04546.13 KXZ42816.1 - 0.85 9.5 18.0 1.4 8.8 18.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RPA43_OB PF17875.1 KXZ42816.1 - 1.3 9.7 5.7 2 9.0 5.7 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF5523 PF17661.1 KXZ42816.1 - 1.3 8.7 18.6 1.8 8.2 18.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF3306 PF11748.8 KXZ42816.1 - 1.5 9.7 12.2 2.3 9.1 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Presenilin PF01080.17 KXZ42816.1 - 1.8 7.2 6.1 2.4 6.8 6.1 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 KXZ42816.1 - 1.9 7.4 5.9 2.5 7.0 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 KXZ42816.1 - 2.4 8.6 6.2 3.5 8.0 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 VIT1 PF01988.19 KXZ42816.1 - 2.6 7.9 5.3 1.3 8.9 3.2 1.5 2 0 0 2 2 2 0 VIT family Connexin PF00029.19 KXZ42816.1 - 2.8 7.6 5.3 4.1 7.1 5.3 1.2 1 0 0 1 1 1 0 Connexin Paf1 PF03985.13 KXZ42816.1 - 2.9 6.8 25.2 4 6.3 25.2 1.1 1 0 0 1 1 1 0 Paf1 DUF1115 PF06544.12 KXZ42816.1 - 3.8 7.6 7.0 5.7 7.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) DUF719 PF05334.13 KXZ42816.1 - 3.9 7.6 8.0 6.4 6.9 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Voldacs PF03517.13 KXZ42816.1 - 4.3 7.5 15.2 8.1 6.6 15.2 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling RR_TM4-6 PF06459.12 KXZ42816.1 - 4.3 7.1 14.1 5.8 6.6 14.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1840 PF08895.11 KXZ42816.1 - 4.4 7.7 8.8 10 6.5 8.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) BSP_II PF05432.11 KXZ42816.1 - 4.8 6.8 26.1 9.1 5.9 26.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) XAP5 PF04921.14 KXZ42816.1 - 6.9 6.4 9.7 9.6 5.9 9.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Med17 PF10156.9 KXZ42816.1 - 7.1 5.2 10.9 10 4.7 10.9 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RAB3GAP2_C PF14656.6 KXZ42816.1 - 9.1 4.4 8.1 13 3.8 8.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus TRAM_LAG1_CLN8 PF03798.16 KXZ42818.1 - 8.4e-37 126.8 19.3 1.3e-36 126.2 19.3 1.3 1 0 0 1 1 1 1 TLC domain FAT PF02259.23 KXZ42819.1 - 3.1e-68 230.5 1.8 3.1e-68 230.5 1.8 1.6 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXZ42819.1 - 1.8e-45 155.7 0.1 3.4e-45 154.8 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KXZ42819.1 - 6e-38 130.3 0.0 1.7e-34 119.1 0.0 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF3385) FATC PF02260.20 KXZ42819.1 - 2.8e-16 59.0 0.3 7.6e-16 57.6 0.3 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KXZ42819.1 - 1.9e-07 31.3 19.6 0.0062 16.9 0.0 7.1 5 1 0 6 6 6 2 HEAT repeats HEAT PF02985.22 KXZ42819.1 - 8.5e-07 28.7 7.6 5.3 7.6 0.0 7.8 7 0 0 7 7 7 2 HEAT repeat TPR_2 PF07719.17 KXZ42819.1 - 0.0026 17.7 0.8 5.9 7.3 0.2 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ42819.1 - 0.0098 15.9 0.7 1.1 9.5 0.1 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 KXZ42819.1 - 0.2 12.2 34.0 0.59 10.7 1.4 9.2 8 1 1 9 9 9 0 HEAT-like repeat HTH_20 PF12840.7 KXZ42819.1 - 2 8.6 4.7 2.7 8.1 0.1 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain TPR_14 PF13428.6 KXZ42819.1 - 3.3 8.8 14.0 4.3 8.4 0.1 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat BAF250_C PF12031.8 KXZ42820.1 - 0.0065 15.8 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa HEAT_EZ PF13513.6 KXZ42820.1 - 0.0099 16.4 0.7 1.7 9.2 0.1 3.5 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KXZ42820.1 - 0.011 16.0 1.9 29 5.3 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat HAD_2 PF13419.6 KXZ42821.1 - 7.7e-21 75.0 0.0 9.6e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ42821.1 - 1.5e-13 51.6 2.4 4.7e-12 46.7 2.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ42821.1 - 0.0004 20.8 0.2 0.00052 20.5 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ42821.1 - 0.016 15.2 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_6 PF13344.6 KXZ42821.1 - 0.061 13.4 0.0 3.1 8.0 0.0 2.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase AAA PF00004.29 KXZ42822.1 - 1.4e-34 119.3 0.0 1.7e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ42822.1 - 9.7e-06 25.3 4.2 9.7e-06 25.3 4.2 2.8 4 0 0 4 4 4 1 AAA+ lid domain AAA_5 PF07728.14 KXZ42822.1 - 0.0015 18.6 0.1 0.083 12.9 0.1 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ42822.1 - 0.0015 19.0 0.0 0.0015 19.0 0.0 3.1 3 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KXZ42822.1 - 0.0031 17.3 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Ribosomal_60s PF00428.19 KXZ42822.1 - 0.016 15.8 8.0 0.016 15.8 8.0 3.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein Vps4_C PF09336.10 KXZ42822.1 - 0.019 14.9 0.0 5.5 7.1 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 KXZ42822.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain CCDC53 PF10152.9 KXZ42822.1 - 0.049 14.0 1.7 0.24 11.8 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex AAA_22 PF13401.6 KXZ42822.1 - 0.11 12.8 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3396 PF11876.8 KXZ42822.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3396) AAA_17 PF13207.6 KXZ42822.1 - 0.15 12.5 0.2 14 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pex14_N PF04695.13 KXZ42823.1 - 0.16 12.6 1.6 0.18 12.5 0.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF563 PF04577.14 KXZ42824.1 - 9e-06 26.0 0.0 1.7e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Arm PF00514.23 KXZ42825.1 - 0.0019 18.2 31.5 0.066 13.3 0.1 7.9 8 1 0 8 8 8 3 Armadillo/beta-catenin-like repeat Sporozoite_P67 PF05642.11 KXZ42826.1 - 0.14 10.2 2.4 0.16 10.0 2.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SpoU_methylase PF00588.19 KXZ42827.1 - 9.5e-10 38.8 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SLT_L PF14718.6 KXZ42827.1 - 0.5 10.5 4.1 3.4 7.9 0.9 2.3 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain IU_nuc_hydro PF01156.19 KXZ42829.1 - 1.7e-44 152.6 0.3 2.4e-44 152.1 0.3 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ROQ_II PF18386.1 KXZ42830.1 - 0.25 11.2 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 Roquin II domain FemAB_like PF04339.12 KXZ42831.1 - 1.3e-90 304.3 0.0 7e-87 291.9 0.0 2.2 1 1 1 2 2 2 2 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 KXZ42831.1 - 0.01 16.0 0.7 0.024 14.8 0.3 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Serglycin PF04360.12 KXZ42831.1 - 3.1 7.7 6.9 7.7 6.5 6.9 1.6 1 0 0 1 1 1 0 Serglycin PAC2 PF09754.9 KXZ42832.1 - 1.3e-15 58.0 0.1 3.7e-15 56.5 0.1 1.6 1 1 0 1 1 1 1 PAC2 family GLTT PF01744.20 KXZ42832.1 - 0.083 12.7 2.0 1.2 8.9 0.4 2.7 2 1 1 3 3 3 0 GLTT repeat (6 copies) Lactamase_B PF00753.27 KXZ42833.1 - 4e-07 30.2 3.8 8.7e-07 29.1 3.8 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 KXZ42833.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily CAP PF00188.26 KXZ42835.1 - 8e-18 65.5 0.0 7.9e-07 30.0 0.0 3.0 1 1 2 3 3 3 2 Cysteine-rich secretory protein family XG_FTase PF03254.13 KXZ42835.1 - 0.0018 17.0 0.0 1.9 7.0 0.0 2.7 3 0 0 3 3 3 2 Xyloglucan fucosyltransferase DUF4786 PF16027.5 KXZ42835.1 - 0.053 14.1 0.1 18 5.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4786) Phage_CII PF05269.11 KXZ42835.1 - 0.096 12.9 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage CII protein CAP PF00188.26 KXZ42837.1 - 3e-08 34.5 0.2 4e-08 34.2 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KXZ42838.1 - 1.8e-09 38.5 8.4 3.3e-05 24.7 1.2 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family CAP PF00188.26 KXZ42839.1 - 2e-12 48.1 0.0 4.9e-08 33.9 0.0 2.1 1 1 1 2 2 2 2 Cysteine-rich secretory protein family XG_FTase PF03254.13 KXZ42839.1 - 0.038 12.6 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase CAP PF00188.26 KXZ42840.1 - 3.4e-08 34.4 0.2 4.5e-08 34.0 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF445 PF04286.12 KXZ42841.1 - 0.064 13.1 7.5 0.081 12.7 5.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF445) YpjP PF14005.6 KXZ42841.1 - 0.11 12.6 0.7 0.29 11.2 0.7 1.8 2 0 0 2 2 2 0 YpjP-like protein MIB_HERC2 PF06701.13 KXZ42841.1 - 0.11 12.7 5.4 0.3 11.3 5.4 1.7 1 1 0 1 1 1 0 Mib_herc2 Nre_C PF04895.12 KXZ42841.1 - 0.36 10.8 0.1 0.36 10.8 0.1 2.9 3 1 0 3 3 3 0 Archaeal Nre, C-terminal CDC37_N PF03234.14 KXZ42841.1 - 0.55 11.1 7.5 0.69 10.8 0.6 2.7 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding pRN1_helical PF13010.6 KXZ42841.1 - 1 9.3 3.5 1.9 8.4 3.5 1.4 1 0 0 1 1 1 0 Primase helical domain VitD-bind_III PF09164.10 KXZ42841.1 - 1.3 9.1 4.7 3.6 7.7 0.1 3.4 2 1 2 4 4 4 0 Vitamin D binding protein, domain III WGG PF10273.9 KXZ42841.1 - 1.9 9.2 4.2 5 7.9 3.5 2.2 2 1 0 2 2 2 0 Pre-rRNA-processing protein TSR2 Tropomyosin_1 PF12718.7 KXZ42841.1 - 4.3 7.5 28.8 0.93 9.6 0.1 3.0 2 1 0 2 2 2 0 Tropomyosin like Guanylate_cyc PF00211.20 KXZ42842.1 - 3e-20 72.6 0.0 2.5e-08 33.8 0.0 3.5 3 1 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain DUF4054 PF13262.6 KXZ42842.1 - 0.34 11.0 3.6 0.29 11.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) DUF4054 PF13262.6 KXZ42843.1 - 0.004 17.2 4.5 0.022 14.8 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4054) K_channel_TID PF07941.11 KXZ42843.1 - 0.16 12.4 14.3 0.14 12.7 7.4 2.9 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Guanylate_cyc PF00211.20 KXZ42844.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ42845.1 - 0.0023 17.6 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MlaD PF02470.20 KXZ42847.1 - 5.9e-10 39.3 0.7 1.1e-09 38.5 0.7 1.4 1 0 0 1 1 1 1 MlaD protein TPR_12 PF13424.6 KXZ42849.1 - 8.7e-19 67.6 29.0 0.00045 20.4 0.0 5.5 4 2 3 7 7 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ42849.1 - 1.7e-15 56.1 10.1 0.0066 16.2 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ42849.1 - 1.4e-14 53.0 8.7 0.014 15.5 0.3 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ42849.1 - 1.4e-13 49.8 10.6 0.00069 19.5 0.4 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ42849.1 - 4.6e-12 45.1 17.0 0.021 14.9 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ42849.1 - 5.6e-09 36.1 10.4 0.11 13.2 0.0 6.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42849.1 - 3.3e-07 30.6 23.4 0.088 13.7 1.0 6.6 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ42849.1 - 5.5e-07 29.3 7.0 0.0014 18.1 0.0 2.6 2 1 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 KXZ42849.1 - 6.1e-06 25.9 10.6 0.014 15.2 0.0 5.9 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ42849.1 - 0.0015 18.7 15.7 0.98 9.6 0.0 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ42849.1 - 0.0024 18.3 11.7 9 6.9 1.9 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ42849.1 - 0.0036 16.9 4.2 3.7 7.3 0.0 4.6 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 KXZ42849.1 - 0.0043 17.7 27.9 0.8 10.4 2.1 6.4 4 2 3 7 7 7 4 Tetratricopeptide repeat RPN7 PF10602.9 KXZ42849.1 - 0.017 14.8 2.1 2.7 7.7 0.0 3.5 3 1 0 3 3 3 0 26S proteasome subunit RPN7 SNAP PF14938.6 KXZ42849.1 - 0.075 12.5 7.6 12 5.2 6.0 2.9 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 KXZ42849.1 - 0.09 13.2 5.1 41 4.9 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ42849.1 - 2.1 9.2 0.0 2.1 9.2 0.0 6.5 8 0 0 8 8 4 0 Tetratricopeptide repeat Atx10homo_assoc PF09759.9 KXZ42852.1 - 9.1e-23 80.2 0.0 1.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 KXZ42852.1 - 0.28 11.5 4.1 1.1 9.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat DNA_pol_E_B PF04042.16 KXZ42854.1 - 3.2e-35 121.4 0.0 4.3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KXZ42854.1 - 2.7e-33 114.8 0.0 3.8e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain CRAL_TRIO PF00650.20 KXZ42855.1 - 1.1e-07 31.8 0.0 1.4e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain LRR_4 PF12799.7 KXZ42856.1 - 0.13 12.7 0.0 3.4 8.2 0.0 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) AbfS_sensor PF18225.1 KXZ42856.1 - 0.18 11.7 0.4 0.34 10.8 0.4 1.4 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain S1 PF00575.23 KXZ42857.1 - 9.2e-28 96.4 0.3 7.5e-18 64.6 0.1 2.9 3 0 0 3 3 3 2 S1 RNA binding domain DUF2103 PF09876.9 KXZ42857.1 - 0.0028 17.6 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 1 Predicted metal-binding protein (DUF2103) CDC48_2 PF02933.17 KXZ42857.1 - 0.045 13.5 0.1 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 ADSL_C PF10397.9 KXZ42857.1 - 0.22 12.1 2.1 0.94 10.1 1.0 2.6 1 1 2 3 3 3 0 Adenylosuccinate lyase C-terminus Ribosomal_L1 PF00687.21 KXZ42858.1 - 8.1e-41 140.0 0.5 1e-40 139.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PASTA PF03793.19 KXZ42858.1 - 0.0096 15.8 0.4 3.7 7.5 0.0 2.6 3 0 0 3 3 3 2 PASTA domain Clathrin PF00637.20 KXZ42859.1 - 2e-173 569.2 11.1 1.1e-29 103.1 1.0 8.4 7 1 1 8 8 8 8 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KXZ42859.1 - 3.1e-25 87.9 0.3 2.8e-24 84.8 0.0 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 KXZ42859.1 - 5.1e-19 67.6 2.1 0.0018 18.5 0.1 7.0 7 0 0 7 7 7 4 Clathrin propeller repeat Clathrin-link PF09268.10 KXZ42859.1 - 2.8e-06 26.6 0.0 6.4e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KXZ42859.1 - 0.0008 18.6 11.0 0.046 12.8 0.7 4.2 5 1 1 6 6 6 2 Coatomer WD associated region TPR_1 PF00515.28 KXZ42859.1 - 0.042 13.7 11.7 2.3 8.2 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ42859.1 - 0.088 13.7 23.3 25 6.1 0.0 10.0 8 3 1 9 9 9 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 KXZ42859.1 - 0.15 12.3 2.0 27 5.1 0.1 3.7 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 L_lactis_ph-MCP PF06673.11 KXZ42859.1 - 0.2 10.6 0.7 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Lactococcus lactis bacteriophage major capsid protein TPR_8 PF13181.6 KXZ42859.1 - 1.2 9.5 15.9 3.5 8.1 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ42859.1 - 3.3 7.5 8.2 13 5.6 0.2 4.5 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 KXZ42859.1 - 8.7 6.6 20.5 22 5.4 0.1 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat CorA PF01544.18 KXZ42860.1 - 0.00012 21.5 3.8 0.0029 17.0 0.1 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Med3 PF11593.8 KXZ42861.1 - 8.5 5.4 6.8 47 3.0 4.7 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal RF-1 PF00472.20 KXZ42862.1 - 2.4e-11 43.6 2.7 3.2e-11 43.2 2.7 1.1 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 KXZ42862.1 - 0.002 18.5 0.8 0.0023 18.3 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF3349 PF11829.8 KXZ42862.1 - 0.14 13.0 1.2 0.32 11.8 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) Cupin_8 PF13621.6 KXZ42863.1 - 4.6e-06 26.5 0.0 7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXZ42863.1 - 0.00042 20.7 0.0 0.00071 20.0 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KXZ42863.1 - 0.012 15.3 0.0 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 Cupin domain QWRF PF04484.12 KXZ42864.1 - 7e-08 32.6 1.9 7e-08 32.6 1.9 2.4 3 0 0 3 3 3 1 QWRF family Arf PF00025.21 KXZ42867.1 - 1.6e-20 73.3 0.0 2.2e-20 72.8 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family tRNA-synt_2b PF00587.25 KXZ42869.1 - 5.4e-39 134.0 0.0 9.2e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXZ42869.1 - 2e-12 47.1 0.0 4.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KXZ42869.1 - 6.2e-09 35.8 0.0 1.4e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain S1 PF00575.23 KXZ42870.1 - 1.4e-38 131.1 8.7 2.9e-19 69.2 1.0 3.3 3 0 0 3 3 3 3 S1 RNA binding domain PCB_OB PF17092.5 KXZ42870.1 - 0.00037 21.2 0.1 0.59 10.9 0.0 3.1 2 1 1 3 3 3 2 Penicillin-binding protein OB-like domain DUF2110 PF09883.9 KXZ42870.1 - 0.016 14.8 2.7 0.068 12.8 1.3 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) RNase_II_C_S1 PF18614.1 KXZ42870.1 - 0.2 11.7 6.2 45 4.1 0.0 4.5 4 0 0 4 4 4 0 RNase II-type exonuclease C-terminal S1 domain EF-hand_1 PF00036.32 KXZ42871.1 - 4.6e-21 72.7 0.1 0.02 14.4 0.0 9.1 9 0 0 9 9 9 5 EF hand EF-hand_7 PF13499.6 KXZ42871.1 - 8.8e-19 67.7 0.0 4.2e-05 23.9 0.0 6.2 6 1 0 6 6 6 4 EF-hand domain pair EF-hand_6 PF13405.6 KXZ42871.1 - 7.9e-18 62.8 1.1 0.32 11.0 0.0 9.4 9 0 0 9 9 9 4 EF-hand domain EF-hand_5 PF13202.6 KXZ42871.1 - 1.4e-16 59.1 1.6 0.0095 15.4 0.0 7.2 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 KXZ42871.1 - 7.1e-06 25.8 0.1 9.6 6.1 0.0 6.7 8 0 0 8 8 8 1 EF-hand domain pair GPI2 PF06432.11 KXZ42872.1 - 7.6e-64 215.8 0.0 8.7e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DAO PF01266.24 KXZ42873.1 - 1.6e-10 41.1 0.0 2.7e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DDDD PF10161.9 KXZ42874.1 - 0.051 13.3 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative mitochondrial precursor protein FH2 PF02181.23 KXZ42876.1 - 1.2e-59 202.4 0.0 1.5e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain AAA_13 PF13166.6 KXZ42876.1 - 0.04 12.6 4.9 0.056 12.1 4.9 1.1 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 KXZ42876.1 - 0.087 12.6 0.8 0.19 11.6 0.4 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 HD_2 PF12917.7 KXZ42876.1 - 0.1 12.3 1.2 0.2 11.4 1.2 1.5 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF4407 PF14362.6 KXZ42876.1 - 0.12 11.8 7.6 0.21 10.9 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2992 PF11208.8 KXZ42876.1 - 0.12 12.7 7.4 0.25 11.6 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Drf_GBD PF06371.13 KXZ42878.1 - 1.6e-05 24.6 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain PH PF00169.29 KXZ42878.1 - 0.00098 19.6 1.8 0.033 14.7 0.1 2.3 1 1 1 2 2 2 1 PH domain SelP_N PF04592.14 KXZ42878.1 - 5.9 6.2 13.8 2.9 7.2 6.6 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Ank_2 PF12796.7 KXZ42879.1 - 1.9e-06 28.3 0.1 0.03 14.9 0.2 4.6 2 1 5 7 7 7 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42879.1 - 2.7e-06 27.8 3.3 0.069 13.8 0.2 5.9 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42879.1 - 0.00016 21.8 3.1 13 6.8 0.0 6.7 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KXZ42879.1 - 0.012 15.9 3.1 0.41 11.0 0.0 4.2 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Peptidase_C65 PF10275.9 KXZ42880.1 - 5.4e-12 45.7 0.0 8.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain LRR_4 PF12799.7 KXZ42881.1 - 2.5e-14 53.1 15.6 1.8e-05 25.0 1.0 3.6 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ42881.1 - 1.3e-13 50.5 26.0 6.8e-07 29.0 4.4 3.1 1 1 2 3 3 3 3 Leucine rich repeat TPR_MLP1_2 PF07926.12 KXZ42881.1 - 2.5e-05 24.4 13.4 5.8e-05 23.2 13.4 1.7 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KXZ42881.1 - 0.00012 22.1 5.0 0.00012 22.1 5.0 1.7 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 KXZ42881.1 - 0.00013 21.9 6.6 0.00019 21.4 6.6 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family LRR_9 PF14580.6 KXZ42881.1 - 0.00048 19.7 1.1 0.0013 18.3 1.0 1.7 1 1 0 1 1 1 1 Leucine-rich repeat DUF4407 PF14362.6 KXZ42881.1 - 0.001 18.5 5.3 0.0015 18.0 5.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KXZ42881.1 - 0.0012 19.0 6.0 0.0012 19.0 6.0 1.6 2 0 0 2 2 1 1 Uncharacterised protein family (UPF0242) N-terminus Laminin_I PF06008.14 KXZ42881.1 - 0.0016 18.2 10.6 0.0028 17.4 10.6 1.3 1 0 0 1 1 1 1 Laminin Domain I HAUS-augmin3 PF14932.6 KXZ42881.1 - 0.0019 17.9 5.1 0.0019 17.9 5.1 1.6 2 0 0 2 2 1 1 HAUS augmin-like complex subunit 3 EzrA PF06160.12 KXZ42881.1 - 0.0029 15.9 6.6 0.0045 15.2 6.6 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA KASH_CCD PF14662.6 KXZ42881.1 - 0.0031 17.4 3.4 0.0031 17.4 3.4 1.9 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 KXZ42881.1 - 0.0031 17.4 3.6 0.0031 17.4 3.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF724) Spc7 PF08317.11 KXZ42881.1 - 0.0043 16.0 8.9 0.0043 16.0 8.9 1.5 2 0 0 2 2 1 1 Spc7 kinetochore protein MAD PF05557.13 KXZ42881.1 - 0.0048 15.3 5.6 0.0079 14.6 5.6 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein DivIC PF04977.15 KXZ42881.1 - 0.0061 16.3 19.2 0.12 12.1 4.7 4.0 2 2 2 4 4 4 2 Septum formation initiator CREPT PF16566.5 KXZ42881.1 - 0.0063 16.7 5.7 0.065 13.4 1.4 3.3 2 1 2 4 4 3 1 Cell-cycle alteration and expression-elevated protein in tumour Fez1 PF06818.15 KXZ42881.1 - 0.0067 16.9 1.4 0.0092 16.4 1.4 1.3 1 0 0 1 1 1 1 Fez1 End3 PF12761.7 KXZ42881.1 - 0.0069 16.6 5.7 0.012 15.8 5.7 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 HALZ PF02183.18 KXZ42881.1 - 0.0078 16.4 5.3 0.063 13.5 0.2 3.3 3 0 0 3 3 3 1 Homeobox associated leucine zipper DUF812 PF05667.11 KXZ42881.1 - 0.0085 15.0 4.6 0.013 14.5 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Nup88 PF10168.9 KXZ42881.1 - 0.0094 13.8 0.7 0.013 13.4 0.7 1.1 1 0 0 1 1 1 1 Nuclear pore component TelA PF05816.11 KXZ42881.1 - 0.01 14.9 4.2 0.016 14.3 4.2 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) HOOK PF05622.12 KXZ42881.1 - 0.012 13.8 4.4 0.019 13.1 4.4 1.2 1 0 0 1 1 1 0 HOOK protein MPS2 PF17060.5 KXZ42881.1 - 0.02 14.2 0.7 0.033 13.4 0.7 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 ATG16 PF08614.11 KXZ42881.1 - 0.033 14.4 15.5 0.36 11.0 10.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4349 PF14257.6 KXZ42881.1 - 0.036 13.5 7.6 0.084 12.3 7.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Filament PF00038.21 KXZ42881.1 - 0.037 13.6 7.8 0.063 12.9 7.8 1.4 1 0 0 1 1 1 0 Intermediate filament protein Med30 PF11315.8 KXZ42881.1 - 0.044 14.0 0.9 0.084 13.1 0.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 30 GAS PF13851.6 KXZ42881.1 - 0.078 12.3 10.7 0.34 10.2 10.7 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KXZ42881.1 - 0.095 12.9 2.3 0.24 11.6 2.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 KXZ42881.1 - 0.1 13.1 9.3 1.6 9.2 2.1 3.3 2 2 1 3 3 3 0 Snapin/Pallidin DUF948 PF06103.11 KXZ42881.1 - 0.15 12.3 1.6 0.48 10.7 0.1 2.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 KXZ42881.1 - 0.15 12.1 14.2 0.31 11.1 14.2 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain V_ATPase_I PF01496.19 KXZ42881.1 - 0.17 9.8 1.6 0.24 9.3 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KXZ42881.1 - 0.17 10.4 5.1 0.26 9.8 5.1 1.1 1 0 0 1 1 1 0 Macoilin family Nup54 PF13874.6 KXZ42881.1 - 0.22 11.6 10.2 0.39 10.8 10.2 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ATP-synt_D PF01813.17 KXZ42881.1 - 0.22 11.3 4.5 0.45 10.3 4.5 1.5 1 0 0 1 1 1 0 ATP synthase subunit D Golgin_A5 PF09787.9 KXZ42881.1 - 0.22 10.9 6.5 0.37 10.2 6.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 LRR_1 PF00560.33 KXZ42881.1 - 0.27 11.9 6.4 90 4.2 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat ADIP PF11559.8 KXZ42881.1 - 0.32 11.1 12.7 0.61 10.2 12.4 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding IFT57 PF10498.9 KXZ42881.1 - 0.32 9.9 4.2 0.54 9.2 4.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KXZ42881.1 - 0.35 10.9 2.8 1.7 8.7 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 KXZ42881.1 - 0.36 11.1 11.6 0.17 12.1 4.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Muted PF14942.6 KXZ42881.1 - 0.43 10.9 7.5 0.085 13.2 3.8 1.7 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein SHE3 PF17078.5 KXZ42881.1 - 0.53 10.0 5.4 1.6 8.4 5.4 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 TSC22 PF01166.18 KXZ42881.1 - 0.56 10.6 5.5 17 5.8 0.0 4.0 4 1 0 4 4 4 0 TSC-22/dip/bun family Occludin_ELL PF07303.13 KXZ42881.1 - 0.57 10.9 5.3 2.3 9.0 1.6 2.5 1 1 1 2 2 2 0 Occludin homology domain DUF3450 PF11932.8 KXZ42881.1 - 0.64 9.3 15.2 4.7 6.4 15.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4201 PF13870.6 KXZ42881.1 - 0.7 9.6 7.4 1.5 8.6 7.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 KXZ42881.1 - 0.71 10.0 8.2 2.8 8.1 1.3 3.3 1 1 2 3 3 3 0 TolA binding protein trimerisation Tup_N PF08581.10 KXZ42881.1 - 0.72 10.2 5.2 0.57 10.5 0.3 2.7 2 1 1 3 3 2 0 Tup N-terminal DUF1640 PF07798.11 KXZ42881.1 - 0.92 9.5 6.0 1.7 8.7 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 KXZ42881.1 - 1 9.5 7.4 0.62 10.3 1.3 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 KXZ42881.1 - 1.1 9.4 10.2 6.2 7.0 0.3 3.3 3 0 0 3 3 3 0 Basic region leucine zipper DUF2203 PF09969.9 KXZ42881.1 - 1.2 9.9 8.3 9.8 6.9 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 KXZ42881.1 - 1.2 9.6 15.4 6 7.4 15.4 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 KXZ42881.1 - 1.3 9.4 14.2 3.5 8.0 14.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LPP PF04728.13 KXZ42881.1 - 1.3 9.4 17.4 0.54 10.7 0.7 4.1 3 1 2 5 5 2 0 Lipoprotein leucine-zipper JAKMIP_CC3 PF16034.5 KXZ42881.1 - 1.5 8.7 10.3 5.1 7.0 10.3 1.9 1 1 0 1 1 1 0 JAKMIP CC3 domain ZapB PF06005.12 KXZ42881.1 - 1.8 9.0 17.3 0.36 11.3 5.1 3.3 2 1 1 3 3 2 0 Cell division protein ZapB GIT_CC PF16559.5 KXZ42881.1 - 1.9 8.4 9.3 20 5.2 0.3 3.0 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KXZ42881.1 - 2.2 9.0 8.5 4.8 7.9 4.9 2.9 2 1 1 3 3 3 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 KXZ42881.1 - 2.3 8.5 11.6 5.2 7.3 5.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.8 KXZ42881.1 - 2.3 8.6 6.5 5.9 7.3 6.5 1.7 1 0 0 1 1 1 0 YlqD protein Rootletin PF15035.6 KXZ42881.1 - 2.6 8.0 11.3 12 5.9 11.3 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion BRE1 PF08647.11 KXZ42881.1 - 4.1 7.6 12.2 16 5.6 10.1 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase WXG100 PF06013.12 KXZ42881.1 - 4.2 7.7 12.6 1.2 9.5 6.0 2.5 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Myc-LZ PF02344.15 KXZ42881.1 - 4.3 7.5 6.0 26 5.0 0.2 3.3 3 0 0 3 3 3 0 Myc leucine zipper domain HalX PF08663.10 KXZ42881.1 - 4.4 7.7 13.5 36 4.8 1.0 3.4 1 1 1 2 2 2 0 HalX domain Sec34 PF04136.15 KXZ42881.1 - 4.5 7.1 6.2 2.5 8.0 3.6 1.8 2 1 0 2 2 1 0 Sec34-like family DUF4200 PF13863.6 KXZ42881.1 - 5.6 7.4 12.0 5.4 7.5 0.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 KXZ42881.1 - 6.2 7.1 9.8 10 6.3 7.8 2.4 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding DUF4472 PF14739.6 KXZ42881.1 - 6.4 7.6 11.7 3.7 8.3 4.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Ax_dynein_light PF10211.9 KXZ42881.1 - 7 6.5 10.3 17 5.3 3.5 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain TMPIT PF07851.13 KXZ42881.1 - 7.5 5.7 5.6 12 5.0 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 KXZ42881.1 - 7.7 7.2 16.5 3.7 8.3 0.3 4.3 2 1 2 4 4 3 0 SlyX Cpn60_TCP1 PF00118.24 KXZ42882.1 - 2.9e-11 42.7 0.0 3.6e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ank_5 PF13857.6 KXZ42883.1 - 9.7e-15 54.4 0.1 1.1e-07 32.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42883.1 - 4.9e-13 48.9 0.0 4.3e-05 23.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXZ42883.1 - 2.6e-12 47.0 0.0 1.3e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42883.1 - 1.3e-11 44.9 0.0 3.3e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ42883.1 - 3.4e-09 36.2 0.1 0.005 17.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Chromo PF00385.24 KXZ42883.1 - 0.16 11.9 0.2 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Evr1_Alr PF04777.13 KXZ42884.1 - 5e-18 65.4 0.0 1.8e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 KXZ42884.1 - 1.9e-16 59.9 0.0 3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXZ42884.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KXZ42884.1 - 0.0029 17.3 0.1 0.0053 16.5 0.1 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KXZ42884.1 - 0.013 15.8 0.1 0.11 12.8 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 KXZ42884.1 - 0.044 13.7 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 KXZ42884.1 - 0.068 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KXZ42884.1 - 0.22 11.8 0.2 0.61 10.3 0.2 1.7 1 0 0 1 1 1 0 Thioredoxin-like Arm PF00514.23 KXZ42885.1 - 2.6e-44 148.0 16.8 5.6e-09 35.7 0.0 10.6 10 1 0 10 10 9 7 Armadillo/beta-catenin-like repeat BTB PF00651.31 KXZ42885.1 - 5.5e-23 81.3 0.0 1.3e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HEAT_2 PF13646.6 KXZ42885.1 - 2.9e-15 56.4 13.5 1.5e-05 25.3 0.1 6.3 3 1 3 6 6 6 5 HEAT repeats HEAT PF02985.22 KXZ42885.1 - 9.9e-11 40.9 10.3 0.97 9.9 0.0 8.2 8 0 0 8 8 8 4 HEAT repeat Atx10homo_assoc PF09759.9 KXZ42885.1 - 3.9e-10 39.6 1.6 0.00024 21.1 0.1 3.9 2 1 2 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 KXZ42885.1 - 1.5e-08 34.9 12.7 0.042 14.4 0.1 6.8 4 2 2 6 6 6 4 HEAT-like repeat V-ATPase_H_N PF03224.14 KXZ42885.1 - 8.8e-08 31.8 0.1 0.00097 18.5 0.1 3.1 2 1 0 2 2 2 1 V-ATPase subunit H Adaptin_N PF01602.20 KXZ42885.1 - 4e-07 29.0 0.2 0.048 12.2 0.2 3.3 1 1 2 3 3 3 3 Adaptin N terminal region DUF5578 PF17741.1 KXZ42885.1 - 0.00016 21.2 0.8 0.0028 17.1 0.0 3.0 2 1 0 3 3 3 1 Family of unknown function (DUF5578) Cnd1 PF12717.7 KXZ42885.1 - 0.00039 20.5 2.2 3 7.9 0.0 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KXZ42885.1 - 0.00088 19.2 2.8 0.16 11.9 0.1 4.1 2 1 3 5 5 5 1 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KXZ42885.1 - 0.0049 17.0 0.0 0.15 12.1 0.0 2.7 2 0 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.13 KXZ42885.1 - 0.01 15.3 0.5 1.1 8.7 0.0 3.1 1 1 2 3 3 3 0 Armadillo-like RTP1_C1 PF10363.9 KXZ42885.1 - 0.035 14.3 1.1 0.17 12.1 0.1 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 KXZ42885.1 - 0.1 13.3 13.4 99 4.1 0.1 7.5 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat IFRD PF05004.13 KXZ42885.1 - 0.6 9.1 3.2 18 4.3 0.0 3.9 1 1 3 4 4 4 0 Interferon-related developmental regulator (IFRD) LRR_6 PF13516.6 KXZ42886.1 - 4.9e-16 57.4 9.2 6.8e-05 22.6 0.6 4.4 4 0 0 4 4 4 4 Leucine Rich repeat LRR_1 PF00560.33 KXZ42886.1 - 0.00019 21.5 0.0 17 6.5 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.7 KXZ42886.1 - 0.00024 21.4 0.8 2.2 8.9 0.9 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ42886.1 - 0.17 11.6 3.0 7.5 6.4 0.6 3.5 2 1 1 3 3 3 0 Leucine rich repeat PRTase_2 PF15609.6 KXZ42887.1 - 0.028 13.9 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Xan_ur_permease PF00860.20 KXZ42888.1 - 6.9e-21 74.4 11.2 1.1e-20 73.7 11.2 1.3 1 0 0 1 1 1 1 Permease family Sulfate_transp PF00916.20 KXZ42888.1 - 0.003 16.4 0.6 0.003 16.4 0.6 2.5 3 0 0 3 3 3 2 Sulfate permease family BTB PF00651.31 KXZ42889.1 - 3e-19 69.3 0.0 4.7e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain RNB PF00773.19 KXZ42890.1 - 6.1e-42 144.1 0.0 7.9e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KXZ42890.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Rrp44-like cold shock domain RNB PF00773.19 KXZ42891.1 - 1.7e-16 60.5 0.0 2.2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KXZ42891.1 - 0.2 12.0 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal BTB PF00651.31 KXZ42892.1 - 0.00022 21.4 0.0 0.00064 19.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KXZ42892.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch SnoaL_4 PF13577.6 KXZ42896.1 - 0.0048 17.0 0.1 5 7.3 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like domain Xan_ur_permease PF00860.20 KXZ42897.1 - 1.9e-26 92.7 27.0 3.6e-19 68.8 10.0 2.2 2 0 0 2 2 2 2 Permease family DUF3987 PF13148.6 KXZ42897.1 - 0.16 10.9 6.3 0.25 10.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Sulfate_transp PF00916.20 KXZ42897.1 - 0.28 9.9 22.0 0.047 12.5 0.3 3.4 3 0 0 3 3 3 0 Sulfate permease family PEHE PF15275.6 KXZ42897.1 - 0.37 11.4 0.8 0.63 10.7 0.8 1.3 1 0 0 1 1 1 0 PEHE domain PseudoU_synth_1 PF01416.20 KXZ42898.1 - 2.5e-14 53.6 0.0 4.1e-09 36.9 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase GILT PF03227.16 KXZ42899.1 - 6e-14 52.2 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DSBA PF01323.20 KXZ42899.1 - 0.022 14.5 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Ank PF00023.30 KXZ42901.1 - 1.6e-25 88.4 0.0 6.7e-07 29.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ42901.1 - 2e-21 75.7 0.2 3.3e-09 36.8 0.0 3.2 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42901.1 - 1.8e-20 73.3 0.0 5e-14 52.6 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42901.1 - 9.7e-16 57.9 0.0 3.4e-06 27.5 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42901.1 - 6.4e-15 53.8 0.0 0.0042 17.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat RT_RNaseH_2 PF17919.1 KXZ42902.1 - 1.5e-21 76.3 0.1 2.4e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ42902.1 - 1.9e-19 70.1 0.0 5.3e-19 68.6 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KXZ42902.1 - 2.5e-08 34.2 0.1 4.5e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ank_5 PF13857.6 KXZ42903.1 - 3.9e-27 94.0 1.1 1.5e-08 34.7 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ42903.1 - 1.1e-24 86.9 0.0 7.8e-15 55.2 0.0 2.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ42903.1 - 1.5e-24 85.3 0.5 4.7e-07 30.0 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KXZ42903.1 - 3.2e-19 67.0 0.1 0.0027 18.0 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ42903.1 - 5.5e-19 68.3 0.2 1.6e-05 25.3 0.0 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF2722 PF10846.8 KXZ42903.1 - 4.2e-06 26.0 8.1 4.2e-06 26.0 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DDHD PF02862.17 KXZ42903.1 - 0.0065 16.7 0.1 0.0065 16.7 0.1 1.1 1 0 0 1 1 1 1 DDHD domain EPL1 PF10513.9 KXZ42903.1 - 0.047 14.1 3.4 0.056 13.8 3.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Pex14_N PF04695.13 KXZ42903.1 - 0.1 13.2 10.8 0.13 12.9 10.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 KXZ42903.1 - 0.2 11.1 5.9 0.24 10.8 5.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 KXZ42903.1 - 0.23 11.4 23.9 0.28 11.2 23.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 KXZ42903.1 - 0.41 9.3 24.1 0.49 9.0 24.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MAM33 PF02330.16 KXZ42903.1 - 0.66 9.9 8.7 0.85 9.5 8.7 1.1 1 0 0 1 1 1 0 Mitochondrial glycoprotein THOC2_N PF16134.5 KXZ42903.1 - 0.9 8.1 4.7 1.4 7.4 4.7 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Band_3_cyto PF07565.13 KXZ42903.1 - 0.91 9.3 4.9 1.1 9.0 4.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TERB2 PF15101.6 KXZ42903.1 - 1 9.4 13.2 1.3 9.0 13.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 KXZ42903.1 - 1.6 7.4 8.8 1.9 7.2 8.8 1.1 1 0 0 1 1 1 0 Presenilin Ilar_coat PF01787.16 KXZ42903.1 - 2.1 8.1 7.3 3.3 7.5 7.3 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein Spt20 PF12090.8 KXZ42903.1 - 3.1 7.4 33.7 4.2 6.9 33.7 1.2 1 0 0 1 1 1 0 Spt20 family NARP1 PF12569.8 KXZ42903.1 - 4.5 6.1 13.6 5.8 5.7 13.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4770 PF15994.5 KXZ42903.1 - 5.4 7.2 10.7 6.9 6.9 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Androgen_recep PF02166.16 KXZ42903.1 - 7.7 5.2 22.7 11 4.7 22.7 1.2 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 KXZ42903.1 - 8.5 7.4 15.8 12 6.9 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) GREB1 PF15782.5 KXZ42903.1 - 8.9 3.3 7.4 9.9 3.1 7.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ank_2 PF12796.7 KXZ42904.1 - 9.3e-34 115.9 1.7 3.6e-10 40.3 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ42904.1 - 1.9e-28 97.6 9.0 3.2e-07 30.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXZ42904.1 - 1.1e-26 92.5 9.6 4.8e-09 36.3 0.0 6.0 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ42904.1 - 3.2e-26 88.5 2.1 0.00022 21.4 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KXZ42904.1 - 3.5e-26 91.2 1.6 5.4e-08 33.2 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeats (many copies) zf-MYND PF01753.18 KXZ42905.1 - 3.1e-07 30.4 11.1 3.1e-07 30.4 11.1 4.3 3 1 0 3 3 3 1 MYND finger zf-Mss51 PF13824.6 KXZ42905.1 - 0.0048 17.0 3.5 0.0048 17.0 3.5 2.9 3 0 0 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 Exostosin PF03016.15 KXZ42907.1 - 5.9e-40 137.3 0.1 2.2e-39 135.5 0.1 2.0 1 1 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ42907.1 - 0.00051 20.3 63.0 0.0043 17.4 14.5 4.4 4 1 1 5 5 5 3 EGF-like domain EGF_Tenascin PF18720.1 KXZ42907.1 - 0.98 9.5 33.3 0.11 12.6 2.7 4.0 3 1 0 3 3 3 0 Tenascin EGF domain DAGAT PF03982.13 KXZ42908.1 - 1.5e-49 168.5 0.0 1.8e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase GHMP_kinases_N PF00288.26 KXZ42908.1 - 0.13 12.6 0.3 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 GHMP kinases N terminal domain zf-CCHC_3 PF13917.6 KXZ42909.1 - 3.1e-05 23.8 0.5 7.6e-05 22.6 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KXZ42909.1 - 7.2e-05 22.7 2.2 0.00015 21.7 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KXZ42909.1 - 0.0052 16.5 5.9 0.013 15.1 5.9 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KXZ42909.1 - 0.028 14.2 0.6 0.055 13.3 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle HYR PF02494.16 KXZ42910.1 - 3.6e-07 30.4 4.5 1.3e-05 25.4 0.6 3.1 1 1 1 2 2 2 2 HYR domain RicinB_lectin_2 PF14200.6 KXZ42910.1 - 8.4e-06 26.4 0.0 0.003 18.3 0.0 2.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like EGF PF00008.27 KXZ42910.1 - 0.0053 17.0 8.4 0.0053 17.0 8.4 9.4 8 1 0 8 8 8 5 EGF-like domain WSC PF01822.19 KXZ42911.1 - 7.1e-09 35.7 1.5 7.1e-09 35.7 1.5 3.3 3 0 0 3 3 3 2 WSC domain PAN_4 PF14295.6 KXZ42911.1 - 0.00074 19.4 0.8 0.00074 19.4 0.8 2.8 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 KXZ42911.1 - 0.0069 16.3 0.8 0.0069 16.3 0.8 2.9 3 0 0 3 3 3 1 PAN domain TACI-CRD2 PF09305.10 KXZ42911.1 - 0.05 13.6 1.7 0.05 13.6 1.7 2.7 3 0 0 3 3 3 0 TACI, cysteine-rich domain Opy2 PF09463.10 KXZ42911.1 - 3.3 8.1 15.7 2.2 8.7 1.3 3.2 2 0 0 2 2 2 0 Opy2 protein BRO1 PF03097.18 KXZ42912.1 - 2.8e-67 227.2 2.9 1e-66 225.3 2.8 1.7 1 1 0 1 1 1 1 BRO1-like domain Fib_alpha PF08702.10 KXZ42912.1 - 0.16 12.2 0.3 0.35 11.0 0.3 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PAS_4 PF08448.10 KXZ42913.1 - 8.7e-08 32.4 0.1 0.0017 18.6 0.0 4.8 5 0 0 5 5 5 1 PAS fold PAS PF00989.25 KXZ42913.1 - 8.6e-07 29.0 0.0 0.0048 16.9 0.0 3.8 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 KXZ42913.1 - 2.9e-05 24.3 0.0 0.049 13.9 0.0 3.6 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 KXZ42913.1 - 0.024 14.7 0.2 0.21 11.6 0.0 2.8 3 0 0 3 3 3 0 PAS domain PAS PF00989.25 KXZ42914.1 - 0.006 16.6 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KXZ42914.1 - 0.018 15.3 0.2 0.14 12.4 0.0 2.6 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.7 KXZ42914.1 - 0.026 14.8 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 KXZ42914.1 - 0.071 13.2 0.1 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 PAS domain p450 PF00067.22 KXZ42915.1 - 4.1e-06 25.8 0.0 6.2e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MiaE_2 PF13794.6 KXZ42915.1 - 0.063 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like ArgoN PF16486.5 KXZ42916.1 - 0.016 15.8 0.0 0.024 15.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of argonaute SprT-like PF10263.9 KXZ42918.1 - 6.8e-20 71.0 0.0 1.1e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Pkinase PF00069.25 KXZ42919.1 - 1.9e-69 234.0 0.0 2.5e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ42919.1 - 1.9e-29 102.7 0.0 2.6e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 KXZ42919.1 - 1.8e-17 63.6 1.7 2.3e-09 37.5 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ42919.1 - 3.3e-17 60.7 3.0 0.00021 20.6 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KXZ42919.1 - 8.5e-13 47.1 4.0 0.00049 19.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KXZ42919.1 - 6.4e-11 41.2 8.9 0.0013 18.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXZ42919.1 - 1.8e-09 37.3 8.2 0.023 14.6 0.0 4.6 2 2 2 4 4 4 3 EF-hand domain pair Kinase-like PF14531.6 KXZ42919.1 - 4.9e-09 35.9 0.0 1.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like SPARC_Ca_bdg PF10591.9 KXZ42919.1 - 0.0014 19.0 0.0 2.7 8.4 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 KXZ42919.1 - 0.005 16.2 0.2 0.015 14.7 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ42919.1 - 0.15 12.0 0.1 25 4.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Lebercilin PF15619.6 KXZ42920.1 - 0.2 11.3 5.4 0.34 10.6 5.4 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 KXZ42920.1 - 2 7.0 4.3 2.8 6.5 4.3 1.1 1 0 0 1 1 1 0 AAA domain MCD_N PF17408.2 KXZ42920.1 - 7.4 6.8 8.0 4 7.6 3.2 2.4 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain Spc7 PF08317.11 KXZ42920.1 - 10 4.9 9.8 42 2.9 9.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein RNA_pol_Rpb6 PF01192.22 KXZ42921.1 - 0.076 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb6 Sporozoite_P67 PF05642.11 KXZ42922.1 - 0.00099 17.3 11.8 0.0013 16.9 11.8 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen MutS_V PF00488.21 KXZ42923.1 - 1.7e-76 256.4 0.2 3.9e-76 255.3 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KXZ42923.1 - 1.5e-35 123.1 4.3 3e-35 122.2 4.3 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXZ42923.1 - 1.2e-10 41.6 0.0 3.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KXZ42923.1 - 9.6e-10 38.7 0.3 2e-09 37.7 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KXZ42923.1 - 1.4e-08 35.1 0.8 3.8e-08 33.7 0.1 2.1 2 0 0 2 2 2 1 MutS domain II Filament PF00038.21 KXZ42923.1 - 0.81 9.2 9.0 0.049 13.2 1.9 2.2 2 0 0 2 2 2 0 Intermediate filament protein FYVE PF01363.21 KXZ42924.1 - 0.058 13.5 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-MYND PF01753.18 KXZ42925.1 - 6.5e-07 29.3 9.9 2.1e-06 27.7 9.9 1.9 1 0 0 1 1 1 1 MYND finger Gp_dh_C PF02800.20 KXZ42927.1 - 1.2e-66 223.1 0.7 2e-66 222.5 0.7 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXZ42927.1 - 7.7e-33 112.9 0.0 2.2e-32 111.4 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXZ42927.1 - 0.036 14.9 0.0 0.13 13.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ELFV_dehydrog PF00208.21 KXZ42927.1 - 0.056 13.2 0.2 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ank_3 PF13606.6 KXZ42928.1 - 1.9e-18 64.6 0.1 5.3e-05 23.3 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KXZ42928.1 - 4.9e-17 62.3 0.0 2.9e-10 40.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ42928.1 - 4e-16 58.9 0.2 0.00032 20.9 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42928.1 - 2.9e-15 55.9 0.4 6.1e-05 23.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXZ42928.1 - 6.1e-15 55.4 0.3 1.6e-11 44.5 0.1 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 KXZ42929.1 - 9.9e-09 34.9 4.1 1.3e-08 34.5 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ42929.1 - 0.0003 20.6 7.3 0.00049 19.9 7.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ42929.1 - 0.00041 20.6 8.6 0.00058 20.1 8.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXZ42929.1 - 0.00047 20.0 8.0 0.00066 19.5 8.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ42929.1 - 0.0019 18.1 8.4 0.0028 17.6 8.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXZ42929.1 - 0.082 12.8 9.6 0.13 12.2 9.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXZ42929.1 - 0.4 10.9 8.7 0.7 10.1 8.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXZ42929.1 - 1.1 9.1 7.3 2 8.3 7.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KXZ42929.1 - 6 7.0 8.5 12 6.1 8.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Ribosomal_L6e PF01159.19 KXZ42930.1 - 9.5e-31 106.6 0.2 1.5e-30 106.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KXZ42930.1 - 0.051 13.8 3.4 0.099 12.9 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein L6, N-terminal domain SQHop_cyclase_C PF13243.6 KXZ42931.1 - 3e-34 118.6 0.1 2e-33 115.8 0.0 1.8 1 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KXZ42931.1 - 2.4e-26 91.2 11.0 5.3e-13 48.5 2.7 3.7 3 1 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KXZ42931.1 - 1.4e-05 24.4 0.2 0.0022 17.1 0.2 3.0 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 KXZ42931.1 - 0.0047 16.0 0.0 0.061 12.3 0.0 2.1 2 1 0 2 2 2 1 A-macroglobulin TED domain SQHop_cyclase_N PF13249.6 KXZ42932.1 - 2e-17 63.2 0.2 7.2e-17 61.4 0.1 1.7 2 0 0 2 2 2 1 Squalene-hopene cyclase N-terminal domain TAFII55_N PF04658.13 KXZ42933.1 - 9.4e-24 83.9 0.0 5.4e-22 78.2 0.0 2.0 1 1 0 1 1 1 1 TAFII55 protein conserved region CCDC144C PF14915.6 KXZ42934.1 - 0.13 11.4 21.1 0.011 14.9 14.6 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Spc7 PF08317.11 KXZ42934.1 - 0.26 10.1 32.9 0.78 8.6 3.4 3.6 2 2 1 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 KXZ42934.1 - 0.96 9.9 28.9 1.3 9.5 0.3 3.6 3 1 0 4 4 4 0 Fez1 DUF2046 PF09755.9 KXZ42934.1 - 0.97 8.6 17.1 8.7 5.5 9.1 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) CALCOCO1 PF07888.11 KXZ42934.1 - 1.6 7.5 33.5 3.3 6.5 6.9 2.4 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like YabA PF06156.13 KXZ42934.1 - 5.7 7.6 13.8 9.4 6.9 1.2 3.8 3 1 0 3 3 3 0 Initiation control protein YabA Filament PF00038.21 KXZ42934.1 - 7.3 6.1 30.7 2.8 7.4 5.2 3.5 2 1 1 3 3 3 0 Intermediate filament protein VTC PF09359.10 KXZ42935.1 - 7.3e-13 48.5 0.0 9.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 KXZ42935.1 - 6.7e-07 29.6 1.1 1.4e-06 28.5 1.2 1.5 1 1 0 1 1 1 1 SPX domain DUF1631 PF07793.11 KXZ42935.1 - 0.77 8.1 7.1 1.1 7.6 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) MORN PF02493.20 KXZ42936.1 - 5.5e-27 92.0 26.5 2.1e-07 30.4 0.3 5.6 5 1 0 5 5 5 4 MORN repeat ECD PF18432.1 KXZ42937.1 - 0.015 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Extracellular Cadherin domain DUF2145 PF09916.9 KXZ42937.1 - 0.049 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) adh_short PF00106.25 KXZ42939.1 - 1.2e-44 152.2 0.2 1.4e-44 151.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ42939.1 - 1.7e-41 142.3 0.6 2.2e-41 142.0 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ42939.1 - 3.4e-11 43.4 0.4 5e-11 42.8 0.4 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXZ42939.1 - 0.0016 17.9 0.1 0.0021 17.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PA PF02225.22 KXZ42939.1 - 0.01 15.8 0.2 0.021 14.8 0.2 1.5 1 0 0 1 1 1 0 PA domain NusB PF01029.18 KXZ42939.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 NusB family PALP PF00291.25 KXZ42939.1 - 0.014 14.8 0.4 0.024 14.1 0.2 1.5 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ThiJ_like PF17124.5 KXZ42941.1 - 1.1e-05 25.2 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KXZ42941.1 - 4e-05 23.5 0.1 0.14 11.9 0.0 2.2 1 1 0 2 2 2 2 DJ-1/PfpI family DUF3884 PF13024.6 KXZ42941.1 - 0.11 12.1 0.0 4 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) Phageshock_PspD PF09584.10 KXZ42942.1 - 0.0032 17.5 1.7 0.004 17.1 0.2 1.9 2 0 0 2 2 2 1 Phage shock protein PspD (Phageshock_PspD) CAP_N PF01213.19 KXZ42942.1 - 0.39 10.2 1.1 0.47 9.9 1.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SAM_1 PF00536.30 KXZ42945.1 - 1.9e-13 50.6 0.0 3.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXZ42945.1 - 6.7e-11 42.1 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KXZ42945.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF1517 PF07466.11 KXZ42946.1 - 5e-54 183.2 0.0 5.7e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF2582 PF10771.9 KXZ42946.1 - 0.032 14.4 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) RRM_1 PF00076.22 KXZ42949.1 - 1.5e-06 27.9 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2HC_2 PF13913.6 KXZ42950.1 - 4.6e-08 32.8 0.2 7.1e-08 32.2 0.2 1.3 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KXZ42950.1 - 0.017 15.9 0.6 0.45 11.5 0.4 2.2 1 1 1 2 2 2 0 C2H2-type zinc finger Ribosomal_S11 PF00411.19 KXZ42950.1 - 0.018 15.4 5.2 0.12 12.7 0.9 2.1 1 1 1 2 2 2 0 Ribosomal protein S11 YhfH PF14149.6 KXZ42950.1 - 0.13 12.3 0.7 0.21 11.6 0.7 1.3 1 0 0 1 1 1 0 YhfH-like protein ADK_lid PF05191.14 KXZ42950.1 - 0.15 12.1 0.6 0.27 11.2 0.6 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid Rad50_zn_hook PF04423.14 KXZ42950.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 KXZ42950.1 - 0.19 12.3 1.0 3 8.5 0.2 2.2 1 1 1 2 2 2 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 KXZ42950.1 - 0.45 10.5 3.1 2.5 8.1 0.1 2.5 2 1 1 3 3 3 0 LYAR-type C2HC zinc finger Hydrolase PF00702.26 KXZ42951.1 - 6.6e-17 62.5 0.0 9.5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ42951.1 - 6.1e-14 52.8 0.0 8.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXZ42951.1 - 0.00031 20.2 0.0 0.0007 19.1 0.0 1.5 1 1 0 1 1 1 1 Putative Phosphatase S6PP PF05116.13 KXZ42951.1 - 0.034 13.7 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 KXZ42951.1 - 0.21 11.7 0.0 17 5.5 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Paf1 PF03985.13 KXZ42955.1 - 0.11 11.5 1.9 0.19 10.7 1.9 1.3 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 KXZ42955.1 - 0.24 11.1 1.7 0.51 10.0 1.7 1.5 1 0 0 1 1 1 0 FAM176 family RhlB PF12300.8 KXZ42956.1 - 4.4 7.4 21.7 6.5 6.9 1.4 2.4 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB FixQ PF05545.11 KXZ42958.1 - 0.0077 16.2 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ FixS PF03597.15 KXZ42958.1 - 0.014 15.1 1.0 0.043 13.5 1.0 1.9 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Sec62 PF03839.16 KXZ42958.1 - 0.19 11.2 0.1 0.39 10.2 0.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 PAS PF00989.25 KXZ42959.1 - 1.6e-07 31.3 0.0 1.6e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KXZ42959.1 - 2.8e-06 27.5 0.0 0.00016 21.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KXZ42959.1 - 4e-06 27.0 0.2 2.3e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KXZ42959.1 - 0.00022 21.1 0.0 0.00087 19.3 0.0 1.9 2 0 0 2 2 2 1 PAS domain TPR_17 PF13431.6 KXZ42959.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat FixQ PF05545.11 KXZ42960.1 - 0.0065 16.4 0.1 0.02 14.8 0.1 1.9 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ CEBP_ZZ PF16366.5 KXZ42960.1 - 0.093 13.0 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain FixS PF03597.15 KXZ42960.1 - 0.26 11.0 2.7 0.74 9.6 2.7 1.8 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Tubulin PF00091.25 KXZ42961.1 - 4.9e-67 225.9 0.0 6.7e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXZ42961.1 - 4.3e-51 172.3 0.0 6.9e-51 171.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXZ42961.1 - 0.0058 16.3 0.0 0.023 14.4 0.0 2.1 3 0 0 3 3 3 1 Tubulin domain ACP_syn_III_C PF08541.10 KXZ42962.1 - 2.8e-39 133.2 0.2 7.2e-39 131.9 0.2 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KXZ42962.1 - 1.5e-30 104.9 0.9 1.5e-30 104.9 0.9 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KXZ42962.1 - 3e-05 23.5 0.2 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.15 KXZ42962.1 - 0.001 19.0 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain WD40 PF00400.32 KXZ42963.1 - 4.4e-66 217.2 19.3 2.4e-09 37.7 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ42963.1 - 1.1e-22 80.1 0.1 0.00097 19.4 0.0 7.0 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXZ42963.1 - 8e-11 41.8 0.3 0.46 9.7 0.0 6.1 3 2 2 6 6 6 5 WD40-like domain eIF2A PF08662.11 KXZ42963.1 - 7.5e-07 29.2 0.3 0.072 13.0 0.0 3.7 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXZ42963.1 - 2.6e-06 26.4 6.0 0.44 9.1 0.0 5.6 1 1 4 7 7 7 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXZ42963.1 - 2.6e-05 23.4 4.6 0.34 9.8 1.2 4.2 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 KXZ42963.1 - 0.036 14.1 0.0 8.1 6.5 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat CEP19 PF14933.6 KXZ42963.1 - 0.26 11.6 0.0 0.38 11.0 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein UPF0640 PF15114.6 KXZ42964.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0640 zf-HIT PF04438.16 KXZ42967.1 - 0.048 13.5 0.4 0.077 12.9 0.4 1.2 1 0 0 1 1 1 0 HIT zinc finger AAA_lid_3 PF17862.1 KXZ42969.1 - 4e-14 52.1 0.4 5.2e-14 51.8 0.4 1.1 1 0 0 1 1 1 1 AAA+ lid domain Big_1 PF02369.16 KXZ42970.1 - 7.3 6.7 9.5 2.8 8.0 0.1 4.2 3 1 1 5 5 5 0 Bacterial Ig-like domain (group 1) VOMI PF03762.17 KXZ42973.1 - 1.5e-05 25.2 0.5 0.00013 22.2 0.5 1.9 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) EF-hand_1 PF00036.32 KXZ42974.1 - 0.00023 20.5 1.4 0.00053 19.3 1.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ42974.1 - 0.0017 17.7 0.8 0.0041 16.5 0.8 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ42974.1 - 0.0048 16.7 0.7 0.013 15.4 0.7 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ42974.1 - 0.0091 16.4 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair PBP_N PF17093.5 KXZ42974.1 - 0.075 13.3 1.2 0.27 11.5 0.1 2.1 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Adaptin_N PF01602.20 KXZ42977.1 - 1.4e-25 89.9 0.4 1.7e-25 89.6 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXZ42977.1 - 0.01 15.9 0.4 0.028 14.5 0.0 1.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Carb_kinase PF01256.17 KXZ42978.1 - 1.6e-37 129.3 1.5 3e-28 99.0 0.0 2.8 2 1 0 2 2 2 2 Carbohydrate kinase cobW PF02492.19 KXZ42979.1 - 1.1e-58 197.7 3.7 1.7e-58 197.1 3.7 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ42979.1 - 2.3e-18 65.9 0.1 4e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KXZ42979.1 - 0.0005 20.0 0.4 0.7 9.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXZ42979.1 - 0.00079 19.8 0.1 0.0024 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KXZ42979.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KXZ42979.1 - 0.013 15.8 0.0 0.059 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXZ42979.1 - 0.041 12.9 0.1 0.076 12.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 KXZ42979.1 - 0.069 12.1 0.6 0.63 9.0 0.1 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KXZ42979.1 - 0.083 12.6 0.8 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXZ42979.1 - 0.29 11.6 3.6 0.38 11.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 KXZ42979.1 - 0.57 8.0 5.0 0.99 7.2 5.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RAP PF08373.10 KXZ42980.1 - 0.0006 19.9 0.0 0.00091 19.3 0.0 1.3 1 0 0 1 1 1 1 RAP domain HD PF01966.22 KXZ42981.1 - 7.1e-05 23.0 0.7 0.00015 22.0 0.7 1.6 1 1 0 1 1 1 1 HD domain T_hemolysin PF12261.8 KXZ42981.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin NolX PF05819.11 KXZ42981.1 - 0.1 11.9 0.3 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 NolX protein PHF5 PF03660.14 KXZ42982.1 - 5.4e-45 151.9 15.1 6.1e-45 151.7 15.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KXZ42982.1 - 0.39 8.5 8.7 0.4 8.5 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KXZ42982.1 - 6.1 7.0 16.8 7.6 6.6 1.8 2.7 1 1 1 2 2 2 0 Double zinc ribbon VSG_B PF13206.6 KXZ42983.1 - 8.9 5.4 7.7 19 4.4 7.7 1.5 1 1 0 1 1 1 0 Trypanosomal VSG domain Fungal_KA1 PF16797.5 KXZ42988.1 - 0.02 14.6 0.2 2.6 7.8 0.0 2.1 1 1 1 2 2 2 0 Fungal kinase associated-1 domain Myco_19_kDa PF05481.12 KXZ42988.1 - 0.037 14.3 0.1 1 9.6 0.0 2.3 2 1 1 3 3 3 0 Mycobacterium 19 kDa lipoprotein antigen PPR_2 PF13041.6 KXZ42988.1 - 0.56 10.4 2.7 33 4.8 0.1 3.1 2 1 1 3 3 3 0 PPR repeat family TAT_ubiq PF07706.12 KXZ42989.1 - 0.089 13.0 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase ubiquitination site Aldose_epim PF01263.20 KXZ42991.1 - 2.5e-06 27.0 0.0 0.00064 19.1 0.0 2.1 2 0 0 2 2 2 2 Aldose 1-epimerase Ank_2 PF12796.7 KXZ42992.1 - 9.2e-29 99.9 0.1 4.9e-08 33.5 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ42992.1 - 9.2e-23 80.3 1.0 1e-06 29.1 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ42992.1 - 8.3e-21 73.5 8.3 0.00013 22.3 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KXZ42992.1 - 3.2e-20 70.1 1.7 0.037 14.6 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat U-box PF04564.15 KXZ42992.1 - 5.7e-20 71.3 0.0 1.2e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain Ank_5 PF13857.6 KXZ42992.1 - 2.1e-18 66.1 2.8 5.8e-07 29.7 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) zf-NOSIP PF15906.5 KXZ42992.1 - 1.6e-05 25.0 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KXZ42992.1 - 0.0032 17.2 0.1 0.0063 16.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit LRR_4 PF12799.7 KXZ42993.1 - 3.7e-29 100.3 11.1 2.1e-06 28.0 0.1 6.2 3 1 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ42993.1 - 1.7e-19 69.3 13.3 2.5e-06 27.1 0.1 4.9 5 1 1 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 KXZ42993.1 - 2.2e-16 59.9 0.6 3.9e-07 29.8 0.0 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KXZ42993.1 - 2.1e-08 33.6 8.3 0.59 10.9 0.0 7.8 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KXZ42993.1 - 0.00019 21.2 16.7 0.47 10.6 0.1 6.4 6 0 0 6 6 6 2 Leucine Rich repeat Chromate_transp PF02417.15 KXZ42994.1 - 2.6e-59 199.9 37.6 1.6e-34 119.3 9.8 2.7 2 1 0 2 2 2 2 Chromate transporter Sua5_yciO_yrdC PF01300.18 KXZ42995.1 - 4.1e-53 179.5 0.0 6e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KXZ42995.1 - 7.3e-27 94.6 0.0 2.2e-26 93.0 0.0 1.8 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding PK PF00224.21 KXZ42996.1 - 0 1515.4 20.6 1e-132 442.3 1.0 4.2 4 0 0 4 4 4 4 Pyruvate kinase, barrel domain PK_C PF02887.16 KXZ42996.1 - 4.1e-63 210.8 8.9 6.1e-19 68.4 0.0 5.2 5 0 0 5 5 5 4 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXZ42996.1 - 7.6e-17 61.2 11.0 0.0002 20.6 0.5 4.8 4 0 0 4 4 4 4 HpcH/HpaI aldolase/citrate lyase family CNF1 PF05785.12 KXZ42996.1 - 2.6e-06 26.9 1.8 0.16 11.2 0.1 3.4 3 0 0 3 3 3 3 Rho-activating domain of cytotoxic necrotizing factor Metalloenzyme PF01676.18 KXZ42996.1 - 0.00029 20.3 0.0 0.37 10.1 0.0 3.5 3 0 0 3 3 3 2 Metalloenzyme superfamily Glu_syn_central PF04898.14 KXZ42996.1 - 0.00034 20.2 0.0 2.6 7.5 0.0 3.7 3 0 0 3 3 3 2 Glutamate synthase central domain Radical_SAM PF04055.21 KXZ42996.1 - 0.0019 18.6 0.0 16 5.8 0.0 3.7 3 0 0 3 3 3 1 Radical SAM superfamily FolB PF02152.18 KXZ42996.1 - 0.018 15.6 0.0 0.072 13.6 0.0 2.0 1 0 0 1 1 1 0 Dihydroneopterin aldolase FAD_syn PF06574.12 KXZ42996.1 - 0.052 13.4 1.2 4.5 7.2 0.0 3.4 3 0 0 3 3 3 0 FAD synthetase Toxin_4 PF00706.17 KXZ42996.1 - 0.087 13.3 0.1 27 5.3 0.0 3.5 3 0 0 3 3 3 0 Anenome neurotoxin Peptidase_C70 PF12385.8 KXZ42996.1 - 0.1 12.6 0.0 32 4.5 0.0 3.7 3 0 0 3 3 3 0 Papain-like cysteine protease AvrRpt2 EF-hand_1 PF00036.32 KXZ42998.1 - 0.00068 19.0 0.1 0.0016 17.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ42998.1 - 0.011 15.1 0.1 0.03 13.8 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ42998.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 KXZ42998.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair VOMI PF03762.17 KXZ42999.1 - 0.23 11.6 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) Pkinase PF00069.25 KXZ43000.1 - 1.1e-21 77.4 0.0 4.5e-14 52.5 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43000.1 - 2.9e-18 66.1 0.0 2.3e-12 46.7 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ43002.1 - 4.2e-30 105.0 0.0 2.8e-23 82.6 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43002.1 - 2.8e-28 98.9 0.0 3.2e-23 82.3 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43002.1 - 0.0002 20.3 0.0 0.00029 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ43002.1 - 0.0083 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA_int_end_N2 PF12928.7 KXZ43004.1 - 4.2e-08 33.2 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term ArsA_ATPase PF02374.15 KXZ43005.1 - 1.5e-101 339.6 0.0 2.9e-101 338.7 0.0 1.4 1 1 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KXZ43005.1 - 1.3e-10 41.5 0.1 8.3e-10 38.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KXZ43005.1 - 4.6e-10 39.6 0.0 7.6e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KXZ43005.1 - 1.3e-06 28.1 0.3 8.7e-05 22.1 0.3 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KXZ43005.1 - 1.3e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KXZ43005.1 - 0.00011 22.0 0.1 0.0083 15.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KXZ43005.1 - 0.00051 19.6 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KXZ43005.1 - 0.00055 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXZ43005.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 KXZ43005.1 - 0.0059 16.4 0.1 0.016 14.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXZ43005.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 KXZ43005.1 - 0.015 14.3 0.1 0.048 12.6 0.0 1.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MipZ PF09140.11 KXZ43005.1 - 0.04 13.2 1.1 0.067 12.5 0.1 1.8 3 0 0 3 3 3 0 ATPase MipZ AAA_16 PF13191.6 KXZ43005.1 - 0.047 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXZ43005.1 - 0.091 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain CTP_synth_N PF06418.14 KXZ43005.1 - 0.1 11.9 0.1 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 CTP synthase N-terminus Peptidase_M28 PF04389.17 KXZ43006.1 - 1.1e-21 77.5 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXZ43006.1 - 0.00033 20.4 0.1 0.0006 19.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Abhydrolase_1 PF00561.20 KXZ43007.1 - 6.3e-11 42.4 0.0 2e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_S21e PF01249.18 KXZ43008.1 - 4.1e-37 126.1 0.0 4.9e-37 125.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e GDPD PF03009.17 KXZ43009.1 - 1.1e-40 140.1 0.0 1.9e-24 86.8 0.0 2.4 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family SelP_N PF04592.14 KXZ43009.1 - 0.73 9.2 5.8 1.2 8.5 5.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PDZ_3 PF17815.1 KXZ43010.1 - 6.6e-17 61.7 0.0 8.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ43010.1 - 2.7e-05 24.4 0.0 5.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Glyoxalase_6 PF18029.1 KXZ43011.1 - 0.13 13.1 1.1 0.51 11.2 1.1 2.0 1 0 0 1 1 1 0 Glyoxalase-like domain ASFV_J13L PF05568.11 KXZ43011.1 - 1.1 8.9 3.2 2.4 7.9 3.2 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Pkinase PF00069.25 KXZ43012.1 - 2.9e-27 95.7 0.0 1.6e-21 76.9 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43012.1 - 1.2e-25 90.3 0.0 4e-21 75.5 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43012.1 - 8.6e-05 21.5 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ43012.1 - 0.042 13.8 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ43012.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF515 PF04415.12 KXZ43012.1 - 0.31 9.4 0.3 0.42 8.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ATP-sulfurylase PF01747.17 KXZ43014.1 - 1.4e-68 230.6 0.0 2.2e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KXZ43014.1 - 2.6e-43 147.4 0.0 4.1e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Scramblase PF03803.15 KXZ43015.1 - 4.5e-07 29.4 0.1 3e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 Scramblase Pkinase_Tyr PF07714.17 KXZ43016.1 - 4.9e-12 45.7 0.0 1.2e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ43016.1 - 4.8e-10 39.2 0.0 1.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain IFRD PF05004.13 KXZ43017.1 - 1.4e-32 113.1 0.5 3.9e-32 111.6 0.5 1.6 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Roughex PF06020.11 KXZ43017.1 - 0.81 8.7 3.0 1.2 8.2 3.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein IFRD_C PF04836.12 KXZ43018.1 - 0.00043 20.8 0.0 0.00052 20.5 0.0 1.2 1 0 0 1 1 1 1 Interferon-related protein conserved region Toprim_2 PF13155.6 KXZ43019.1 - 0.11 12.9 0.0 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 Toprim-like Nrap_D5 PF17406.2 KXZ43020.1 - 4.3e-36 124.1 0.0 8.5e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 KXZ43020.1 - 8.3e-29 100.7 0.0 1.5e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 KXZ43020.1 - 1.1e-27 96.8 0.0 1.9e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 KXZ43020.1 - 1.3e-23 83.5 0.0 6.1e-21 74.8 0.0 2.2 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KXZ43020.1 - 1.6e-19 70.4 0.0 3.3e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KXZ43020.1 - 7.3e-15 55.4 0.0 1.2e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 6 Peptidase_A22B PF04258.13 KXZ43021.1 - 2.8e-50 171.5 6.3 6.3e-48 163.7 6.3 2.1 1 1 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KXZ43021.1 - 3.1e-07 30.3 0.0 3.1e-07 30.3 0.0 2.5 4 0 0 4 4 4 1 PA domain TMEM132D_C PF15706.5 KXZ43021.1 - 0.74 9.6 2.9 9.1 6.1 0.2 2.8 2 1 1 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term WD40 PF00400.32 KXZ43022.1 - 5.7e-08 33.3 10.0 0.084 13.8 0.0 8.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Aldo_ket_red PF00248.21 KXZ43023.1 - 9.2e-39 133.4 0.0 3.9e-38 131.3 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3349 PF11829.8 KXZ43023.1 - 0.16 12.8 0.0 0.69 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Aldo_ket_red PF00248.21 KXZ43024.1 - 1.2e-08 34.5 0.0 1.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PAC4 PF16093.5 KXZ43025.1 - 3.6e-06 27.1 0.0 4.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Glyco_transf_28 PF03033.20 KXZ43027.1 - 1e-14 54.8 0.1 3.2e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXZ43027.1 - 0.28 9.9 0.0 0.48 9.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PA14 PF07691.12 KXZ43028.1 - 0.078 12.8 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 PA14 domain BetaGal_dom4_5 PF13364.6 KXZ43028.1 - 0.27 11.8 5.3 0.088 13.4 1.4 2.0 1 1 0 2 2 2 0 Beta-galactosidase jelly roll domain Myb_DNA-bind_4 PF13837.6 KXZ43031.1 - 0.00081 19.7 1.8 0.0015 18.9 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KXZ43031.1 - 0.18 11.9 0.8 0.5 10.5 0.8 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Ion_trans PF00520.31 KXZ43032.1 - 2e-79 266.3 0.0 6.8e-53 179.4 0.9 2.0 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KXZ43032.1 - 0.021 13.5 12.8 0.24 10.0 1.0 3.6 4 0 0 4 4 4 0 Polycystin cation channel Ion_trans PF00520.31 KXZ43033.1 - 2.6e-101 338.0 21.0 4.2e-50 170.3 0.2 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 KXZ43033.1 - 1.1e-06 27.6 29.8 0.00058 18.6 5.4 5.2 4 1 0 5 5 5 4 Polycystin cation channel DUF1664 PF07889.12 KXZ43034.1 - 0.027 14.5 0.5 0.027 14.5 0.5 7.9 5 2 3 9 9 9 0 Protein of unknown function (DUF1664) RTC PF01137.21 KXZ43034.1 - 0.035 13.3 0.0 0.1 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase Synaptobrevin PF00957.21 KXZ43034.1 - 6 6.7 5.9 6.4 6.6 2.7 2.8 2 0 0 2 2 2 0 Synaptobrevin Thi4 PF01946.17 KXZ43036.1 - 8.5e-107 355.7 0.8 1e-106 355.4 0.8 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXZ43036.1 - 5.2e-06 26.3 3.9 2.5e-05 24.1 1.2 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ43036.1 - 9.5e-06 24.9 3.5 0.00023 20.4 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXZ43036.1 - 1.9e-05 24.8 0.2 5.8e-05 23.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ43036.1 - 3.4e-05 23.2 0.1 4.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXZ43036.1 - 0.0003 19.9 0.1 0.00059 19.0 0.1 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXZ43036.1 - 0.0047 16.9 1.4 0.011 15.8 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXZ43036.1 - 0.013 14.3 1.0 0.019 13.7 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KXZ43036.1 - 0.031 13.4 0.4 0.29 10.1 0.6 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXZ43036.1 - 0.032 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RTP1_C2 PF10304.9 KXZ43036.1 - 0.2 11.4 0.4 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 AD PF09793.9 KXZ43037.1 - 5.5e-26 90.5 0.1 7.6e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Anticodon-binding domain DUF4169 PF13770.6 KXZ43037.1 - 0.003 17.8 0.4 0.012 15.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4169) GP63 PF17471.2 KXZ43037.1 - 0.082 13.1 0.1 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Gene product 63 GST_N PF02798.20 KXZ43038.1 - 7.5e-18 64.7 0.0 9.9e-17 61.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXZ43038.1 - 3.6e-11 43.3 0.0 5.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXZ43038.1 - 9.3e-08 32.2 0.0 3.7e-07 30.2 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXZ43038.1 - 1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ43038.1 - 9.5e-07 29.0 0.1 1.8e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ43038.1 - 2.1e-05 24.4 0.1 3.9e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXZ43038.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXZ43038.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.7 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein RRM_1 PF00076.22 KXZ43039.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.26 KXZ43041.1 - 1.5e-11 44.1 0.2 3.5e-11 42.9 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ACT PF01842.25 KXZ43041.1 - 0.00017 21.3 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KXZ43041.1 - 0.0032 18.0 0.0 0.0072 16.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain LRR_8 PF13855.6 KXZ43042.1 - 1.8e-27 94.9 14.3 1.1e-05 25.1 0.6 8.2 5 2 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KXZ43042.1 - 1.6e-17 63.3 11.5 0.0002 21.7 0.2 8.6 6 3 3 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ43042.1 - 0.00016 21.8 4.8 1.7e+02 3.4 0.0 9.0 11 0 0 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 KXZ43042.1 - 0.00055 19.8 12.8 7.1 7.0 0.0 8.8 10 0 0 10 10 10 1 Leucine Rich repeat Glyoxalase PF00903.25 KXZ43044.1 - 1.2e-24 87.0 0.0 1.3e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXZ43044.1 - 8.7e-06 26.0 0.0 3.2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXZ43044.1 - 1.1e-05 26.2 0.0 1.7e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain PIG-X PF08320.12 KXZ43044.1 - 0.15 12.0 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 PIG-X / PBN1 Glyoxalase_2 PF12681.7 KXZ43044.1 - 0.18 11.8 0.0 2.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Glyoxalase-like domain UPF0193 PF05250.11 KXZ43045.1 - 1.1e-13 51.5 4.4 1.3e-13 51.3 4.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Holin_BhlA PF10960.8 KXZ43045.1 - 0.047 13.7 0.9 0.074 13.0 0.9 1.3 1 0 0 1 1 1 0 BhlA holin family EccE PF11203.8 KXZ43046.1 - 0.0041 17.4 0.8 0.0043 17.4 0.8 1.2 1 0 0 1 1 1 1 Putative type VII ESX secretion system translocon, EccE MRP-S33 PF08293.11 KXZ43047.1 - 3.5e-07 30.4 0.1 3.9e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Methyltransf_16 PF10294.9 KXZ43048.1 - 2.5e-15 56.7 0.0 6e-15 55.4 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KXZ43048.1 - 8.2e-08 32.9 0.8 1.5e-06 28.8 0.8 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ43048.1 - 5.6e-07 29.3 1.2 6e-07 29.2 0.2 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXZ43048.1 - 8.2e-07 29.0 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXZ43048.1 - 3.4e-06 26.7 0.1 4.3e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KXZ43048.1 - 8.1e-06 26.5 0.0 1.8e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ43048.1 - 2.4e-05 24.9 1.8 0.00011 22.8 0.6 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ43048.1 - 0.0085 15.9 0.0 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ank_2 PF12796.7 KXZ43049.1 - 1e-08 35.6 1.4 7e-06 26.5 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 KXZ43049.1 - 6.3e-07 29.2 0.6 1.1e-06 28.4 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_3 PF13606.6 KXZ43049.1 - 1.2e-05 25.3 0.9 0.12 13.0 0.3 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXZ43049.1 - 3.1e-05 24.2 0.7 0.14 12.5 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43049.1 - 0.00011 22.5 7.5 0.083 13.4 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXZ43049.1 - 0.00012 22.5 0.7 0.019 15.5 0.1 3.3 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Prok-RING_4 PF14447.6 KXZ43049.1 - 0.00019 21.2 2.9 0.00069 19.4 2.9 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ43049.1 - 0.001 19.4 1.4 0.0021 18.4 1.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXZ43049.1 - 0.0025 17.8 2.2 0.0025 17.8 2.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain FeS PF04060.13 KXZ43049.1 - 0.0048 16.5 2.1 0.02 14.6 2.1 2.1 1 0 0 1 1 1 1 Putative Fe-S cluster zf-C3HC4 PF00097.25 KXZ43049.1 - 0.0099 15.7 1.4 0.023 14.6 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXZ43049.1 - 3.4 7.9 7.2 0.54 10.5 1.5 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Bclt PF15318.6 KXZ43050.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.8 2 1 1 3 3 3 0 Putative Bcl-2 like protein of testis TFIIA PF03153.13 KXZ43051.1 - 0.1 12.5 13.8 0.14 12.1 13.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KXZ43051.1 - 9.4 4.4 9.6 12 4.0 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Acetyltransf_10 PF13673.7 KXZ43053.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ43053.1 - 0.051 13.8 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3008 PF11450.8 KXZ43053.1 - 0.094 12.9 1.2 0.26 11.5 1.2 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) Trimer_CC PF08954.11 KXZ43053.1 - 0.14 11.8 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Trimerisation motif Pkinase PF00069.25 KXZ43056.1 - 2.2e-15 56.7 0.0 3.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43056.1 - 4.3e-09 36.0 0.0 6.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_20 PF12840.7 KXZ43057.1 - 0.1 12.6 2.0 0.21 11.7 2.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain EP400_N PF15790.5 KXZ43057.1 - 0.38 9.6 2.2 0.54 9.0 2.2 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal RicinB_lectin_2 PF14200.6 KXZ43058.1 - 4.5e-132 431.1 63.2 1.5e-10 41.7 0.1 23.6 13 9 12 25 25 25 23 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ43058.1 - 4.5e-105 346.9 65.7 1e-12 48.4 2.4 16.0 10 5 5 16 16 16 15 Ricin-type beta-trefoil lectin domain Glyco_hydro_9 PF00759.19 KXZ43058.1 - 1.1e-56 193.1 6.3 1.6e-56 192.6 6.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Pilin_PilX PF11530.8 KXZ43058.1 - 5e-05 23.2 0.0 8.9 6.3 0.0 6.6 9 0 0 9 9 9 1 Minor type IV pilin, PilX TM2 PF05154.16 KXZ43058.1 - 7 7.1 7.0 30 5.0 0.2 3.3 3 0 0 3 3 3 0 TM2 domain MutS_V PF00488.21 KXZ43059.1 - 3.1e-16 60.0 0.1 1.1e-12 48.4 0.0 2.6 3 0 0 3 3 3 2 MutS domain V AAA_27 PF13514.6 KXZ43059.1 - 0.046 13.3 0.1 0.096 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain RicinB_lectin_2 PF14200.6 KXZ43060.1 - 1.9e-97 320.2 46.4 2.3e-12 47.5 0.3 16.8 8 7 9 17 17 17 17 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ43060.1 - 1.3e-87 290.5 38.8 1.3e-12 48.1 0.0 11.5 9 4 1 10 10 10 10 Ricin-type beta-trefoil lectin domain CRM1_repeat_3 PF18787.1 KXZ43060.1 - 0.053 13.6 0.2 0.47 10.6 0.1 2.7 3 0 0 3 3 3 0 CRM1 / Exportin repeat 3 Dioxygenase_C PF00775.21 KXZ43060.1 - 0.08 12.4 0.1 1e+02 2.3 0.0 4.9 5 0 0 5 5 5 0 Dioxygenase DEC-1_N PF04625.13 KXZ43060.1 - 0.27 10.2 5.9 0.46 9.4 5.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glyco_hydro_9 PF00759.19 KXZ43061.1 - 1.8e-47 162.7 2.5 2.5e-47 162.2 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 RicinB_lectin_2 PF14200.6 KXZ43061.1 - 4.3e-25 88.3 9.2 4.3e-07 30.6 0.0 7.4 5 2 3 8 8 8 6 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ43061.1 - 5e-17 62.3 4.0 4.5e-12 46.3 0.1 4.4 5 0 0 5 5 5 2 Ricin-type beta-trefoil lectin domain MutS_V PF00488.21 KXZ43062.1 - 1.3e-48 165.6 0.0 3.1e-48 164.3 0.0 1.7 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXZ43062.1 - 2.6e-17 63.7 0.0 5.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain III AAA_27 PF13514.6 KXZ43062.1 - 0.023 14.3 0.0 0.073 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain MutS_IV PF05190.18 KXZ43062.1 - 0.027 14.8 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV Paramyx_P_V_C PF03210.13 KXZ43063.1 - 0.041 13.7 0.0 0.047 13.5 0.0 1.0 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal THF_DHG_CYH_C PF02882.19 KXZ43063.1 - 0.12 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SASA PF03629.18 KXZ43064.1 - 8.9e-06 25.5 0.0 0.00029 20.6 0.0 2.0 1 1 1 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase Mannosyl_trans PF05007.13 KXZ43064.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase (PIG-M) TPX2 PF06886.11 KXZ43065.1 - 0.47 10.7 24.7 0.038 14.2 6.5 2.7 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Mito_carr PF00153.27 KXZ43066.1 - 1.6e-45 152.9 0.4 2.1e-16 59.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RINGv PF12906.7 KXZ43067.1 - 3.5e-12 46.3 7.1 5.7e-12 45.6 7.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXZ43067.1 - 0.22 11.9 7.1 0.39 11.1 7.1 1.4 1 0 0 1 1 1 0 Ring finger domain ABC2_membrane PF01061.24 KXZ43069.1 - 0.0019 17.6 5.3 0.0026 17.2 5.3 1.1 1 0 0 1 1 1 1 ABC-2 type transporter DUF4129 PF13559.6 KXZ43069.1 - 0.6 10.4 4.0 7.9 6.8 4.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) Pkinase PF00069.25 KXZ43072.1 - 4.2e-14 52.5 0.0 6.7e-05 22.4 0.1 4.3 3 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43072.1 - 6.1e-11 42.1 0.0 4.1e-07 29.5 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 KXZ43072.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXZ43072.1 - 0.026 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase G-patch PF01585.23 KXZ43073.1 - 7.8e-09 35.3 2.4 1.7e-08 34.2 2.4 1.6 1 0 0 1 1 1 1 G-patch domain Atrophin-1 PF03154.15 KXZ43073.1 - 0.18 10.1 4.4 0.21 9.8 4.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family PLATZ PF04640.14 KXZ43074.1 - 5.7e-21 74.9 1.2 8.8e-21 74.3 1.2 1.3 1 0 0 1 1 1 1 PLATZ transcription factor Ecl1 PF12855.7 KXZ43074.1 - 0.0058 17.8 3.9 0.0061 17.7 2.4 1.9 1 1 1 2 2 2 1 ECL1/2/3 zinc binding proteins zf-HIT PF04438.16 KXZ43074.1 - 0.44 10.4 2.9 0.75 9.7 2.9 1.4 1 0 0 1 1 1 0 HIT zinc finger Ank_4 PF13637.6 KXZ43075.1 - 1.7e-10 41.2 3.4 0.36 11.5 0.0 5.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43075.1 - 7.2e-10 39.3 0.1 0.013 16.0 0.1 4.6 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43075.1 - 0.00077 19.7 7.9 39 5.3 0.0 7.1 8 0 0 8 8 8 0 Ankyrin repeat DUF434 PF04256.12 KXZ43075.1 - 0.0087 15.7 0.0 0.23 11.2 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF434) Ank_5 PF13857.6 KXZ43075.1 - 8 6.9 10.9 53 4.3 0.2 5.0 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ43076.1 - 4.3e-08 33.5 5.4 0.038 14.6 0.1 6.9 7 1 1 8 8 8 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43076.1 - 1.8e-06 28.5 0.4 0.086 13.4 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ43076.1 - 1.8e-05 24.9 8.1 1.2 9.5 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43076.1 - 0.021 15.4 3.6 1.4e+02 3.6 0.0 6.9 8 0 0 8 8 8 0 Ankyrin repeat DUF1843 PF08898.10 KXZ43076.1 - 0.2 12.2 4.9 47 4.6 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) Pkinase PF00069.25 KXZ43077.1 - 3.6e-27 95.4 0.0 1.3e-12 47.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43077.1 - 1.2e-23 83.7 0.0 2.5e-10 40.1 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43077.1 - 0.21 10.3 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Fez1 PF06818.15 KXZ43078.1 - 0.0037 17.7 11.6 0.0037 17.7 11.6 14.3 5 2 8 13 13 13 4 Fez1 Peptidase_M11 PF05548.11 KXZ43079.1 - 3e-41 141.6 0.0 5.9e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Gametolysin peptidase M11 P_proprotein PF01483.20 KXZ43079.1 - 3.2e-20 71.9 0.0 2.5e-12 46.6 0.0 3.5 3 1 0 3 3 3 2 Proprotein convertase P-domain Reprolysin_4 PF13583.6 KXZ43079.1 - 0.073 12.7 0.3 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ABC2_membrane PF01061.24 KXZ43081.1 - 0.00019 20.9 4.0 0.00025 20.5 4.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter TetR_C_12 PF16914.5 KXZ43081.1 - 0.33 11.1 3.9 0.44 10.7 0.5 2.3 2 1 0 2 2 2 0 Bacterial transcriptional repressor C-terminal ABC_tran PF00005.27 KXZ43082.1 - 2e-19 70.5 0.0 5.4e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KXZ43082.1 - 7.6e-06 25.9 0.3 0.023 14.5 0.1 3.1 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXZ43082.1 - 0.00079 19.9 0.1 0.0044 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KXZ43082.1 - 0.003 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KXZ43082.1 - 0.2 11.5 0.1 0.42 10.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Ion_trans PF00520.31 KXZ43083.1 - 5.8e-07 29.0 11.2 7.7e-07 28.6 11.2 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXZ43083.1 - 0.0096 14.6 6.6 0.017 13.8 6.6 1.4 1 1 0 1 1 1 1 Polycystin cation channel XhlA PF10779.9 KXZ43083.1 - 0.13 12.5 0.5 1.5 9.1 0.0 2.4 1 1 1 2 2 2 0 Haemolysin XhlA COG2 PF06148.11 KXZ43083.1 - 0.48 10.5 3.1 0.45 10.6 0.4 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4061 PF13270.6 KXZ43083.1 - 0.51 10.7 4.6 0.39 11.1 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF3357 PF11837.8 KXZ43083.1 - 0.63 10.5 0.0 0.63 10.5 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) DHR10 PF18595.1 KXZ43083.1 - 1.1 9.4 9.1 2.3 8.3 9.1 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain XK-related PF09815.9 KXZ43084.1 - 1.2e-11 44.3 0.3 2e-11 43.5 0.3 1.3 1 1 0 1 1 1 1 XK-related protein LRR_6 PF13516.6 KXZ43084.1 - 0.00035 20.4 1.6 0.0012 18.7 0.1 2.6 2 0 0 2 2 2 1 Leucine Rich repeat Ank_2 PF12796.7 KXZ43085.1 - 1.5e-69 230.6 27.8 6.4e-16 58.7 1.1 5.9 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43085.1 - 8.4e-61 201.6 8.9 8.9e-11 42.1 0.1 8.0 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43085.1 - 3e-57 189.9 27.0 6.3e-10 39.1 0.0 10.8 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43085.1 - 1.8e-56 186.3 37.0 4e-06 27.0 0.0 11.2 11 0 0 11 11 11 11 Ankyrin repeat Ank_3 PF13606.6 KXZ43085.1 - 1.8e-48 156.8 17.3 2.8e-05 24.2 0.0 11.3 11 0 0 11 11 11 10 Ankyrin repeat DUF1949 PF09186.11 KXZ43085.1 - 0.034 14.0 0.0 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) Brix PF04427.18 KXZ43088.1 - 2.1e-36 125.8 0.2 2.8e-36 125.5 0.2 1.1 1 0 0 1 1 1 1 Brix domain dNK PF01712.19 KXZ43089.1 - 4.5e-46 157.3 0.0 7.8e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KXZ43089.1 - 0.0016 19.0 0.0 0.045 14.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ43089.1 - 0.0024 18.0 0.0 0.041 14.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXZ43089.1 - 0.06 13.6 0.0 4.7 7.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Methyltransf_28 PF02636.17 KXZ43090.1 - 3.2e-61 207.3 0.0 2.1e-37 129.2 0.0 2.5 2 1 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase TFIIA PF03153.13 KXZ43090.1 - 0.21 11.5 9.7 0.3 11.1 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 KXZ43090.1 - 0.88 8.5 13.3 1.3 7.9 13.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DAO PF01266.24 KXZ43092.1 - 9.8e-21 74.7 4.7 2.9e-17 63.3 4.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase tRNA_int_endo PF01974.17 KXZ43093.1 - 4.7e-19 68.2 0.0 8.9e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF5320 PF17253.2 KXZ43093.1 - 4.5 8.4 13.5 11 7.1 13.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) TMEM208_SND2 PF05620.11 KXZ43094.1 - 8.9e-42 142.7 0.1 1e-41 142.5 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF4051 PF13260.6 KXZ43094.1 - 0.017 14.8 0.1 0.043 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) zf-CCHC PF00098.23 KXZ43095.1 - 0.0027 17.7 1.7 0.0027 17.7 1.7 1.6 2 0 0 2 2 2 1 Zinc knuckle DUF2946 PF11162.8 KXZ43095.1 - 0.0093 16.6 2.1 0.017 15.8 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) zf-C2H2_10 PF16588.5 KXZ43095.1 - 0.09 12.5 3.0 0.14 11.9 3.0 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger RsfS PF02410.15 KXZ43096.1 - 1.6e-21 76.5 0.0 3.5e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Nucleoside_tran PF01733.18 KXZ43097.1 - 0.00036 20.0 1.7 0.00074 19.0 1.7 1.4 1 0 0 1 1 1 1 Nucleoside transporter PAS_4 PF08448.10 KXZ43098.1 - 1e-07 32.2 0.0 1.8e-05 25.0 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KXZ43098.1 - 1.7e-06 28.0 0.0 0.0064 16.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KXZ43098.1 - 3e-05 24.2 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 KXZ43098.1 - 0.053 13.6 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 PAS domain SUIM_assoc PF16619.5 KXZ43099.1 - 0.96 9.6 9.2 0.085 12.9 3.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CTNNBL PF08216.11 KXZ43101.1 - 3.5e-30 104.2 0.0 4.9e-29 100.5 0.0 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 KXZ43101.1 - 0.0068 15.8 0.0 0.29 10.5 0.0 2.3 1 1 1 2 2 2 1 Mo25-like UNC45-central PF11701.8 KXZ43101.1 - 0.012 15.6 0.1 0.069 13.1 0.1 2.4 1 1 2 3 3 3 0 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 KXZ43101.1 - 0.016 15.1 0.1 3.4 7.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) zf-MYND PF01753.18 KXZ43102.1 - 0.005 16.9 10.6 0.01 15.9 10.6 1.6 1 0 0 1 1 1 1 MYND finger DUF1771 PF08590.10 KXZ43102.1 - 2.8 8.4 6.0 6.2 7.3 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Glycolytic PF00274.19 KXZ43103.1 - 4e-119 397.4 0.0 4.8e-119 397.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I RCC_reductase PF06405.11 KXZ43104.1 - 0.0049 16.1 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 2 Red chlorophyll catabolite reductase (RCC reductase) F-box-like PF12937.7 KXZ43105.1 - 0.00052 19.9 0.2 0.0014 18.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ43105.1 - 0.0019 18.0 0.8 0.01 15.7 0.1 2.6 3 0 0 3 3 3 1 F-box domain VSG_B PF13206.6 KXZ43105.1 - 0.14 11.4 0.3 0.24 10.6 0.3 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain MMR_HSR1 PF01926.23 KXZ43106.1 - 2.4e-07 30.8 0.0 4.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ43106.1 - 0.00024 20.7 0.6 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.13 KXZ43106.1 - 0.00029 20.0 1.1 0.008 15.3 0.1 2.2 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KXZ43106.1 - 0.079 12.9 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 RsgA GTPase SfsA_N PF17746.1 KXZ43107.1 - 1.4e-14 54.0 0.0 1.7e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 SfsA N-terminal OB domain SfsA PF03749.13 KXZ43107.1 - 5.8e-12 45.7 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain Angiomotin_C PF12240.8 KXZ43108.1 - 0.032 13.8 0.5 0.032 13.8 0.5 1.6 2 0 0 2 2 2 0 Angiomotin C terminal AAA_13 PF13166.6 KXZ43108.1 - 0.047 12.3 0.4 0.061 12.0 0.4 1.0 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 KXZ43108.1 - 0.16 11.3 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 FAM76 protein PKcGMP_CC PF16808.5 KXZ43108.1 - 0.81 9.6 3.0 0.83 9.6 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sod_Fe_C PF02777.18 KXZ43109.1 - 5e-41 139.0 0.3 8.5e-41 138.3 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXZ43109.1 - 3e-29 101.3 1.1 6e-29 100.3 1.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GAD-like PF08887.11 KXZ43109.1 - 0.051 13.3 1.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 GAD-like domain PLATZ PF04640.14 KXZ43110.1 - 0.17 12.5 0.0 0.27 11.9 0.0 1.3 1 0 0 1 1 1 0 PLATZ transcription factor Rieske PF00355.26 KXZ43111.1 - 1.7e-12 47.1 0.1 2.6e-12 46.5 0.1 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXZ43111.1 - 4.1e-10 39.5 0.0 5.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain 4HBT PF03061.22 KXZ43112.1 - 3.4e-08 33.7 0.0 0.00086 19.6 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily E1-E2_ATPase PF00122.20 KXZ43114.1 - 1.5e-23 83.3 0.0 3.3e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 KXZ43114.1 - 4.3e-14 52.7 0.0 8.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KXZ43114.1 - 7e-06 26.5 4.9 0.00014 22.2 4.9 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ43114.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Collagen PF01391.18 KXZ43115.1 - 0.001 18.7 10.0 0.0027 17.4 10.0 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Apolipoprotein PF01442.18 KXZ43115.1 - 0.17 11.7 29.5 0.26 11.1 29.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain LMBR1 PF04791.16 KXZ43115.1 - 2.6 6.9 5.7 3.4 6.5 5.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.16 KXZ43115.1 - 3.9 7.4 4.6 5.7 6.9 4.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Baculo_PP31 PF05311.11 KXZ43115.1 - 5.8 6.3 9.9 8.2 5.8 9.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) ACP_PD PF04336.12 KXZ43115.1 - 7.2 7.1 10.4 15 6.0 10.4 1.5 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Presenilin PF01080.17 KXZ43115.1 - 9.1 4.9 12.1 14 4.3 12.1 1.2 1 0 0 1 1 1 0 Presenilin AA_kinase PF00696.28 KXZ43118.1 - 3.2e-30 105.5 0.3 4.1e-30 105.1 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family Mito_carr PF00153.27 KXZ43119.1 - 3.5e-31 107.0 13.3 4.1e-15 55.5 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KXZ43120.1 - 2.1e-05 23.8 0.1 4.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ43120.1 - 0.00025 20.4 0.8 0.00043 19.7 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXZ43120.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXZ43120.1 - 0.004 17.0 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KXZ43120.1 - 0.017 15.6 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair DUF5345 PF17280.2 KXZ43120.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) EF-hand_1 PF00036.32 KXZ43123.1 - 2.8e-05 23.3 0.0 6.7e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ43123.1 - 0.00032 20.0 0.1 0.0007 19.0 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43123.1 - 0.0021 17.8 0.0 0.0072 16.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ43123.1 - 0.0086 16.5 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ43123.1 - 0.025 14.4 0.0 0.21 11.5 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 KXZ43125.1 - 0.00023 20.5 0.1 0.00053 19.3 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ43125.1 - 0.0036 16.7 0.2 0.0073 15.8 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43125.1 - 0.0069 16.2 0.3 0.018 15.0 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KXZ43125.1 - 0.076 12.9 0.2 0.5 10.2 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair Malectin_like PF12819.7 KXZ43125.1 - 0.079 12.1 6.3 0.45 9.6 0.2 2.3 2 0 0 2 2 2 0 Malectin-like domain Haemagg_act PF05860.13 KXZ43125.1 - 0.084 12.8 10.0 1 9.2 1.1 2.5 3 0 0 3 3 3 0 haemagglutination activity domain DUF4682 PF15733.5 KXZ43125.1 - 0.21 12.2 3.2 8.7 7.0 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4682) SpaA PF17802.1 KXZ43125.1 - 0.27 11.6 4.5 12 6.4 0.2 2.5 2 0 0 2 2 2 0 Prealbumin-like fold domain SAP130_C PF16014.5 KXZ43125.1 - 10 5.1 10.5 13 4.7 10.5 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus PPR_2 PF13041.6 KXZ43127.1 - 0.0018 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 PPR repeat family Pkinase PF00069.25 KXZ43128.1 - 2.3e-17 63.3 0.0 9.1e-17 61.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43128.1 - 1.1e-05 24.9 0.0 8.3e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ43128.1 - 0.0013 18.7 1.0 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3694 PF12473.8 KXZ43128.1 - 0.0024 18.5 0.0 0.019 15.6 0.0 2.1 1 1 0 1 1 1 1 Kinesin protein Pkinase_fungal PF17667.1 KXZ43128.1 - 0.033 13.0 0.0 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KXZ43128.1 - 0.16 11.3 0.2 0.28 10.5 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRCH PF03967.13 KXZ43129.1 - 0.4 10.9 3.0 13 6.0 0.2 2.3 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region EF-hand_1 PF00036.32 KXZ43132.1 - 9.8e-06 24.8 0.0 1.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ43132.1 - 0.00011 21.5 0.1 0.00018 20.8 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43132.1 - 0.00093 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ43132.1 - 0.0036 17.7 0.0 0.0062 17.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ43132.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair Mu-conotoxin PF05374.12 KXZ43135.1 - 0.029 14.4 2.9 4.9 7.2 0.2 2.3 2 0 0 2 2 2 0 Mu-Conotoxin CBS PF00571.28 KXZ43136.1 - 1.5e-11 44.5 0.5 3.5e-11 43.4 0.4 1.6 2 0 0 2 2 2 1 CBS domain RhlB PF12300.8 KXZ43136.1 - 0.023 14.8 9.4 0.023 14.8 9.4 2.0 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB EF-hand_1 PF00036.32 KXZ43137.1 - 7.3e-05 22.0 0.2 0.00063 19.1 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXZ43137.1 - 0.0024 17.3 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43137.1 - 0.0062 16.4 0.0 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KXZ43137.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair CarboxypepD_reg PF13620.6 KXZ43138.1 - 0.00011 22.4 0.2 0.00011 22.4 0.2 1.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 KXZ43138.1 - 0.0048 17.1 0.0 0.007 16.6 0.0 1.2 1 0 0 1 1 1 1 SdrD B-like domain DUF2012 PF09430.10 KXZ43138.1 - 0.034 14.3 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Ub-Mut7C PF14451.6 KXZ43139.1 - 1.6e-05 24.6 4.1 20 5.1 0.0 5.5 4 2 2 6 6 6 5 Mut7-C ubiquitin Chlam_PMP PF02415.17 KXZ43139.1 - 0.0052 17.2 72.9 0.12 12.9 1.4 11.2 11 0 0 11 11 11 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Colipase_C PF02740.14 KXZ43139.1 - 1.2 9.3 4.9 1.1e+02 3.0 0.0 4.6 5 0 0 5 5 5 0 Colipase, C-terminal domain WSC PF01822.19 KXZ43140.1 - 9e-12 45.0 1.1 1.7e-11 44.2 1.1 1.5 1 0 0 1 1 1 1 WSC domain Chlam_PMP PF02415.17 KXZ43140.1 - 4.9e-06 26.7 15.2 0.077 13.5 0.2 4.8 4 0 0 4 4 4 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat F5_F8_type_C PF00754.25 KXZ43140.1 - 0.0016 18.6 0.0 0.0067 16.6 0.0 2.0 1 1 0 1 1 1 1 F5/8 type C domain Metallophos_C PF14008.6 KXZ43141.1 - 3.3e-12 47.1 0.1 2.7e-06 28.1 0.0 2.7 2 0 0 2 2 2 2 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 KXZ43141.1 - 0.054 14.0 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase ABC_tran PF00005.27 KXZ43142.1 - 3.9e-43 147.3 0.0 7.8e-24 84.7 0.0 3.5 2 1 1 3 3 3 3 ABC transporter ABC_membrane PF00664.23 KXZ43142.1 - 6.3e-30 104.7 7.2 6e-15 55.6 2.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KXZ43142.1 - 4.1e-08 33.4 0.1 0.84 9.4 0.0 4.0 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXZ43142.1 - 4.2e-07 30.5 0.8 0.016 15.6 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXZ43142.1 - 1.9e-06 27.5 0.2 0.022 14.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXZ43142.1 - 6.1e-06 26.3 0.4 0.062 13.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 KXZ43142.1 - 0.00013 22.2 1.9 0.15 12.2 0.2 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 KXZ43142.1 - 0.00021 21.6 0.5 0.15 12.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KXZ43142.1 - 0.00021 21.8 0.1 0.069 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXZ43142.1 - 0.00026 20.9 0.1 0.059 13.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KXZ43142.1 - 0.00027 20.5 0.4 1.6 8.1 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KXZ43142.1 - 0.00088 18.9 0.2 0.82 9.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KXZ43142.1 - 0.0012 19.0 1.3 0.062 13.4 0.1 2.4 2 0 0 2 2 2 1 Dynamin family GRP PF07172.11 KXZ43142.1 - 0.011 16.4 13.6 0.011 16.4 13.6 5.7 5 1 1 6 6 1 0 Glycine rich protein family AAA_33 PF13671.6 KXZ43142.1 - 0.023 14.9 0.1 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXZ43142.1 - 0.041 13.6 0.0 4.3 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXZ43142.1 - 0.051 12.6 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KXZ43142.1 - 0.058 13.2 0.2 12 5.5 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KXZ43142.1 - 0.093 12.6 0.8 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KXZ43142.1 - 0.093 12.1 1.0 3.9 6.7 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KXZ43142.1 - 0.11 12.3 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 KXZ43142.1 - 0.25 10.9 0.8 2.7 7.5 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaJ PF00226.31 KXZ43143.1 - 0.0032 17.5 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Tmemb_cc2 PF10267.9 KXZ43143.1 - 0.018 14.2 3.6 0.052 12.7 3.2 1.9 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF3474 PF11960.8 KXZ43143.1 - 0.035 14.3 0.0 0.074 13.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) QWRF PF04484.12 KXZ43143.1 - 0.17 11.6 11.2 0.069 12.9 8.9 1.6 1 1 1 2 2 2 0 QWRF family Fez1 PF06818.15 KXZ43143.1 - 0.2 12.1 10.9 0.46 10.9 10.9 1.5 1 0 0 1 1 1 0 Fez1 Atg14 PF10186.9 KXZ43143.1 - 5 6.1 7.8 8.6 5.3 7.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cyclin_N PF00134.23 KXZ43144.1 - 3.8e-16 59.0 0.0 5.2e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ43144.1 - 0.0039 17.3 3.0 0.0039 17.3 3.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 KXZ43144.1 - 0.062 13.7 0.6 0.16 12.4 0.6 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain TB2_DP1_HVA22 PF03134.19 KXZ43146.1 - 1e-26 92.7 2.2 1.7e-26 91.9 2.2 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family LRR_8 PF13855.6 KXZ43147.1 - 6.3e-22 77.1 25.6 4.8e-09 35.8 0.8 5.5 5 2 1 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 KXZ43147.1 - 8.5e-18 64.2 22.2 1.6e-06 28.4 0.7 6.9 2 1 6 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ43147.1 - 3.7e-07 29.8 22.7 0.57 10.9 1.8 8.0 8 1 0 8 8 8 4 Leucine Rich Repeat LRR_9 PF14580.6 KXZ43147.1 - 0.00011 21.8 0.5 0.041 13.4 0.2 2.6 2 1 0 2 2 2 2 Leucine-rich repeat Inhibitor_I36 PF03995.13 KXZ43148.1 - 0.067 13.1 8.7 3.8 7.5 0.1 3.6 3 0 0 3 3 3 0 Peptidase inhibitor family I36 Lustrin_cystein PF14625.6 KXZ43148.1 - 2.4 8.6 27.8 1.3 9.4 0.1 4.7 3 2 2 5 5 5 0 Lustrin, cysteine-rich repeated domain SRCR PF00530.18 KXZ43150.1 - 5.7e-10 39.6 0.5 8.8e-10 39.0 0.5 1.4 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ43150.1 - 3.7e-06 27.4 0.0 5.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KXZ43150.1 - 0.0019 18.7 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 Hepsin, SRCR domain SRCR PF00530.18 KXZ43152.1 - 9.4e-85 279.6 16.8 3.1e-18 66.1 0.2 10.3 8 3 0 8 8 8 8 Scavenger receptor cysteine-rich domain VOMI PF03762.17 KXZ43152.1 - 2.6e-09 37.4 0.0 7.5e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) SRCR_2 PF15494.6 KXZ43152.1 - 0.00028 21.4 12.2 1.6 9.3 0.5 6.3 7 0 0 7 7 7 2 Scavenger receptor cysteine-rich domain VWA_2 PF13519.6 KXZ43153.1 - 0.002 18.7 0.0 0.0047 17.6 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXZ43153.1 - 0.0041 17.1 0.0 0.0048 16.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain WSC PF01822.19 KXZ43154.1 - 5.2e-10 39.4 3.4 4.1e-05 23.7 1.5 2.8 2 1 1 3 3 3 2 WSC domain F5_F8_type_C PF00754.25 KXZ43154.1 - 0.00028 21.0 0.0 0.00073 19.7 0.0 1.7 1 1 0 1 1 1 1 F5/8 type C domain ATG16 PF08614.11 KXZ43156.1 - 0.021 15.1 9.9 0.097 12.9 0.9 2.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 KXZ43156.1 - 8.1 6.7 9.5 0.86 9.9 1.1 2.8 2 2 0 2 2 2 0 Tho complex subunit 7 DUF3754 PF12576.8 KXZ43157.1 - 6e-18 65.1 0.2 1.4e-17 63.9 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) cNMP_binding PF00027.29 KXZ43158.1 - 4.5e-16 58.7 0.8 0.0058 16.7 0.0 5.9 5 1 0 5 5 5 4 Cyclic nucleotide-binding domain DUF1681 PF07933.14 KXZ43161.1 - 1.5e-43 148.0 0.0 5.4e-43 146.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) bZIP_1 PF00170.21 KXZ43161.1 - 7.8e-10 38.7 7.0 1.1e-09 38.3 4.1 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ43161.1 - 2.4e-09 37.1 4.8 2.4e-09 37.1 4.8 3.0 3 0 0 3 3 3 1 Basic region leucine zipper FlaC_arch PF05377.11 KXZ43161.1 - 0.0068 16.8 1.1 0.017 15.5 1.1 1.6 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) RasGAP_C PF03836.15 KXZ43161.1 - 0.0088 16.2 0.5 0.0088 16.2 0.5 2.1 2 0 0 2 2 2 1 RasGAP C-terminus Complex1_LYR_2 PF13233.6 KXZ43161.1 - 0.58 10.9 5.7 30 5.4 6.0 2.7 2 1 0 2 2 2 0 Complex1_LYR-like ADIP PF11559.8 KXZ43161.1 - 2.4 8.2 13.8 1.8 8.6 5.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KXZ43161.1 - 3 7.7 15.8 1.6 8.6 0.2 3.5 2 1 1 3 3 3 0 Septum formation initiator YabA PF06156.13 KXZ43161.1 - 6.1 7.5 9.0 0.35 11.5 0.9 2.7 2 1 1 3 3 3 0 Initiation control protein YabA Sec15 PF04091.12 KXZ43162.1 - 8.9e-18 64.8 0.0 5.4e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Exocyst complex subunit Sec15-like Pkinase PF00069.25 KXZ43163.1 - 1.5e-60 204.8 0.0 1.9e-59 201.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43163.1 - 2.4e-44 151.6 0.0 7.5e-44 149.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43163.1 - 0.0019 17.1 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ43163.1 - 0.011 15.0 0.0 0.068 12.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KXZ43163.1 - 0.028 14.4 7.2 0.63 9.9 0.0 3.7 4 0 0 4 4 4 0 Phosphotransferase enzyme family DnaJ PF00226.31 KXZ43165.1 - 5.6e-25 87.3 0.4 1e-24 86.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF5320 PF17253.2 KXZ43165.1 - 0.0023 19.0 10.1 0.034 15.2 0.0 2.9 3 0 0 3 3 3 2 Family of unknown function (DUF5320) CAP_N PF01213.19 KXZ43165.1 - 0.0054 16.3 6.3 0.09 12.2 7.8 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KXZ43165.1 - 0.14 12.2 2.5 0.22 11.6 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Latarcin PF10279.9 KXZ43165.1 - 0.15 12.4 0.8 9.5 6.7 0.0 2.5 3 0 0 3 3 3 0 Latarcin precursor PRIMA1 PF16101.5 KXZ43165.1 - 1.2 9.2 5.0 1.9 8.6 5.0 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 NTF2 PF02136.20 KXZ43166.1 - 9.5e-28 97.2 0.0 1.1e-27 97.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KXZ43166.1 - 0.00016 22.0 0.0 0.00019 21.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) AF-4 PF05110.13 KXZ43167.1 - 9.1e-05 20.8 0.0 0.00013 20.3 0.0 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein EMP24_GP25L PF01105.24 KXZ43168.1 - 2e-48 164.8 0.3 2.2e-48 164.6 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 KXZ43168.1 - 0.00012 22.3 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 SdrD B-like domain CarboxypepD_reg PF13620.6 KXZ43168.1 - 0.0021 18.3 0.1 0.0037 17.5 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF722 PF05263.11 KXZ43168.1 - 0.011 15.9 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Siah-Interact_N PF09032.11 KXZ43168.1 - 0.034 14.4 0.9 0.23 11.8 0.3 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal DUF2569 PF10754.9 KXZ43168.1 - 0.13 12.7 0.1 0.18 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Dynamin_N PF00350.23 KXZ43169.1 - 7.5e-08 32.6 0.1 8.7e-08 32.4 0.1 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXZ43169.1 - 1.6e-05 25.0 0.1 1.9e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXZ43169.1 - 2.1e-05 25.1 0.1 2.5e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXZ43169.1 - 4e-05 23.6 0.0 4.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KXZ43169.1 - 0.0061 17.1 0.1 0.0071 16.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXZ43169.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KXZ43169.1 - 0.013 14.5 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 KXZ43169.1 - 0.015 14.5 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain GBP PF02263.19 KXZ43169.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AIG1 PF04548.16 KXZ43169.1 - 0.018 14.4 0.1 0.02 14.2 0.1 1.1 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 KXZ43169.1 - 0.022 14.3 0.3 0.03 13.9 0.3 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 KXZ43169.1 - 0.026 13.6 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Adeno_IVa2 PF02456.15 KXZ43169.1 - 0.034 12.9 0.0 0.037 12.8 0.0 1.0 1 0 0 1 1 1 0 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.18 KXZ43169.1 - 0.052 12.9 0.2 0.069 12.5 0.2 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 KXZ43169.1 - 0.056 14.0 0.1 0.072 13.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KXZ43169.1 - 0.057 12.3 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 KXZ43169.1 - 0.058 12.4 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXZ43169.1 - 0.062 13.7 0.1 0.069 13.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KXZ43169.1 - 0.063 12.7 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXZ43169.1 - 0.088 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KXZ43169.1 - 0.098 12.7 0.6 0.14 12.2 0.6 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KXZ43169.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.6 KXZ43169.1 - 0.12 12.1 0.2 0.15 11.9 0.2 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KXZ43169.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Roc PF08477.13 KXZ43169.1 - 0.19 11.9 0.1 0.29 11.4 0.1 1.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase KAP_NTPase PF07693.14 KXZ43169.1 - 0.19 10.9 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.6 KXZ43169.1 - 0.2 11.9 0.2 0.27 11.5 0.2 1.2 1 0 0 1 1 1 0 AAA domain Abhydrolase_9 PF10081.9 KXZ43169.1 - 0.2 10.7 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Glucan_synthase PF02364.15 KXZ43170.1 - 1.4e-160 536.2 0.1 2.6e-160 535.3 0.1 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KXZ43170.1 - 8.3e-09 35.9 0.2 7.1e-08 32.9 0.2 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 adh_short_C2 PF13561.6 KXZ43171.1 - 1.2e-66 224.7 8.0 1.5e-66 224.3 8.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ43171.1 - 1.1e-51 175.0 6.2 1.4e-51 174.8 6.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ43171.1 - 3.2e-08 33.7 7.7 8.9e-08 32.2 6.6 2.3 1 1 2 3 3 3 1 KR domain AdoHcyase_NAD PF00670.21 KXZ43171.1 - 0.0022 18.1 1.9 0.0047 17.0 1.9 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FKBP_C PF00254.28 KXZ43172.1 - 2.9e-13 49.9 0.0 4.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Abhydro_lipase PF04083.16 KXZ43173.1 - 5.7e-08 32.2 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KXZ43173.1 - 1.4e-05 24.9 0.1 0.00055 19.7 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold MCM PF00493.23 KXZ43177.1 - 9e-98 325.8 0.0 1.4e-97 325.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KXZ43177.1 - 3.9e-26 91.3 1.8 7.5e-26 90.4 1.8 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXZ43177.1 - 3.2e-12 47.0 0.0 8.4e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXZ43177.1 - 4.5e-06 26.2 0.1 9.4e-05 21.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_OB PF17207.3 KXZ43177.1 - 3.3e-05 23.7 0.0 7.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 KXZ43177.1 - 0.0022 18.0 0.0 0.0083 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXZ43177.1 - 0.0029 17.5 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3486 PF11985.8 KXZ43177.1 - 0.08 13.4 0.3 2.1 8.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3486) AAA_16 PF13191.6 KXZ43177.1 - 0.14 12.5 0.7 1.5 9.2 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain Mg_chelatase_C PF13335.6 KXZ43177.1 - 1.7 9.3 5.4 13 6.5 3.7 2.7 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Filament PF00038.21 KXZ43178.1 - 0.026 14.1 12.5 0.048 13.2 4.7 2.1 1 1 0 2 2 2 0 Intermediate filament protein KASH_CCD PF14662.6 KXZ43178.1 - 0.028 14.3 11.3 0.06 13.2 11.0 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4715 PF15835.5 KXZ43178.1 - 0.17 12.0 6.7 0.24 11.5 0.7 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4715) Spc7 PF08317.11 KXZ43178.1 - 0.32 9.8 13.8 0.15 10.9 1.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.20 KXZ43178.1 - 0.49 9.7 14.9 0.74 9.1 1.4 2.2 2 0 0 2 2 2 0 Tropomyosin MscS_porin PF12795.7 KXZ43178.1 - 1.4 8.4 27.8 28 4.1 16.1 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF2407_C PF13373.6 KXZ43178.1 - 1.4 9.1 4.3 1.6 8.9 3.3 1.6 1 1 0 1 1 1 0 DUF2407 C-terminal domain FlxA PF14282.6 KXZ43178.1 - 1.7 8.7 15.2 0.36 10.9 2.2 2.7 1 1 1 2 2 2 0 FlxA-like protein Atg14 PF10186.9 KXZ43178.1 - 1.8 7.6 8.6 2.7 7.0 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KXZ43178.1 - 2.8 7.7 6.0 13 5.6 5.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 KXZ43178.1 - 4.7 6.5 5.8 20 4.4 6.0 1.7 1 1 1 2 2 2 0 FAM76 protein CHDCT2 PF08074.11 KXZ43178.1 - 4.9 7.3 7.8 3.5 7.8 1.5 2.2 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF4763 PF15960.5 KXZ43178.1 - 5 6.3 13.6 0.25 10.6 2.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) LON_substr_bdg PF02190.16 KXZ43179.1 - 0.0021 17.9 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain SlyX PF04102.12 KXZ43179.1 - 0.082 13.5 0.2 0.17 12.5 0.2 1.5 1 0 0 1 1 1 0 SlyX tRNA_synt_2f PF02092.17 KXZ43179.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit MarR_2 PF12802.7 KXZ43180.1 - 0.012 15.5 0.1 0.044 13.7 0.1 1.8 1 1 1 2 2 2 0 MarR family Peptidase_M43 PF05572.13 KXZ43181.1 - 5.9e-10 39.3 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXZ43181.1 - 0.00011 22.5 0.0 0.00018 21.7 0.0 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Asp_protease_2 PF13650.6 KXZ43183.1 - 0.036 14.7 0.0 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease BetaGal_dom4_5 PF13364.6 KXZ43184.1 - 0.00012 22.6 0.9 0.047 14.3 0.1 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain DUF4982 PF16355.5 KXZ43184.1 - 0.0023 17.8 0.1 2.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4982) PA14 PF07691.12 KXZ43184.1 - 0.045 13.6 0.1 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 PA14 domain CBM60 PF16841.5 KXZ43184.1 - 0.057 13.8 1.5 0.079 13.4 0.6 1.9 2 1 0 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding tRNA_anti-codon PF01336.25 KXZ43187.1 - 1.5e-16 60.2 0.4 2.4e-16 59.5 0.4 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2 PF00152.20 KXZ43187.1 - 1.9e-11 43.6 0.1 7e-05 22.1 0.2 2.4 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) MDMPI_N PF11716.8 KXZ43187.1 - 5.4 7.7 13.1 0.18 12.5 4.0 2.5 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain PhoLip_ATPase_C PF16212.5 KXZ43188.1 - 3.7e-09 36.7 0.6 4.1e-09 36.6 0.6 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal TT_ORF2 PF02957.15 KXZ43189.1 - 0.62 11.0 0.0 0.62 11.0 0.0 2.9 3 0 0 3 3 3 0 TT viral ORF2 Ank_2 PF12796.7 KXZ43191.1 - 8e-27 93.7 5.0 1.3e-13 51.3 0.8 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43191.1 - 4.6e-18 64.8 3.8 2.9e-07 30.6 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KXZ43191.1 - 4e-16 57.5 0.3 1.9e-05 24.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXZ43191.1 - 2.1e-15 56.8 0.7 1.1e-08 35.4 0.1 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43191.1 - 5.6e-13 48.8 4.4 0.00011 22.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) UBA PF00627.31 KXZ43191.1 - 0.00084 19.2 9.0 1.1 9.3 0.1 3.3 3 0 0 3 3 3 3 UBA/TS-N domain Rotamase_2 PF13145.6 KXZ43191.1 - 0.006 17.4 0.3 0.1 13.4 0.2 2.0 2 0 0 2 2 2 1 PPIC-type PPIASE domain Ank_2 PF12796.7 KXZ43192.1 - 1e-123 404.2 45.2 2.1e-15 57.1 0.2 9.1 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43192.1 - 3.7e-101 327.5 39.6 1.6e-06 28.3 0.0 17.2 17 0 0 17 17 17 17 Ankyrin repeat Ank_3 PF13606.6 KXZ43192.1 - 3.8e-94 297.2 14.3 2.5e-05 24.3 0.0 17.3 17 0 0 17 17 17 17 Ankyrin repeat Ank_4 PF13637.6 KXZ43192.1 - 9.8e-91 297.1 14.0 3.4e-11 43.4 0.0 11.5 7 3 3 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43192.1 - 8.6e-73 239.4 29.8 4.5e-06 26.8 0.2 13.9 3 2 12 15 15 15 15 Ankyrin repeats (many copies) TIR_2 PF13676.6 KXZ43192.1 - 1.8e-13 51.1 0.0 4.3e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KXZ43192.1 - 4.3e-05 23.4 0.0 7.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 TIR domain DUF1593 PF07632.11 KXZ43192.1 - 0.018 14.5 8.0 4.8 6.5 0.1 6.2 3 3 3 7 7 7 0 Protein of unknown function (DUF1593) Phospholip_B PF04916.13 KXZ43192.1 - 0.25 9.9 0.1 2.2 6.7 0.0 2.4 1 1 1 3 3 3 0 Phospholipase B Calponin PF00402.18 KXZ43192.1 - 3.8 7.3 16.4 17 5.1 0.2 7.3 7 0 0 7 7 7 0 Calponin family repeat Ank_4 PF13637.6 KXZ43193.1 - 1.5e-56 188.1 1.5 3.2e-13 49.9 0.0 5.7 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43193.1 - 2.8e-56 188.1 3.6 5.1e-15 55.8 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43193.1 - 4.9e-48 159.5 4.9 8.9e-08 32.3 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KXZ43193.1 - 1.8e-45 147.7 0.3 1e-05 25.5 0.0 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KXZ43193.1 - 4.1e-41 138.5 12.1 5.6e-10 39.3 0.0 6.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) RVP PF00077.20 KXZ43193.1 - 0.076 13.3 1.7 1.7 9.0 0.0 3.8 3 2 3 6 6 6 0 Retroviral aspartyl protease DUF3368 PF11848.8 KXZ43193.1 - 0.13 12.1 0.6 80 3.1 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) UBA PF00627.31 KXZ43193.1 - 0.41 10.6 5.6 16 5.5 0.4 4.9 5 0 0 5 5 5 0 UBA/TS-N domain VWA_3_C PF18571.1 KXZ43193.1 - 3.1 7.8 12.0 26 4.8 0.0 5.2 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain ABC_tran PF00005.27 KXZ43194.1 - 0.15 12.6 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Ank_2 PF12796.7 KXZ43196.1 - 3.7e-132 431.2 44.5 2.5e-17 63.2 0.7 11.3 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43196.1 - 4.6e-97 306.2 20.4 8.3e-05 22.7 0.0 21.5 21 0 0 21 21 21 21 Ankyrin repeat Ank PF00023.30 KXZ43196.1 - 3.2e-95 308.8 59.1 2.3e-06 27.8 0.1 21.6 22 0 0 22 22 22 21 Ankyrin repeat Ank_4 PF13637.6 KXZ43196.1 - 7.9e-91 297.4 23.8 2.7e-09 37.4 0.1 15.7 3 2 15 19 19 19 19 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43196.1 - 2.1e-78 257.4 59.8 7e-06 26.2 0.1 19.3 2 1 19 21 21 21 21 Ankyrin repeats (many copies) MBT PF02820.18 KXZ43196.1 - 0.0039 17.5 0.0 98 3.4 0.0 5.2 5 0 0 5 5 5 0 mbt repeat NlpE_C PF17185.4 KXZ43196.1 - 0.022 15.0 0.6 25 5.2 0.0 5.5 5 2 4 9 9 9 0 NlpE C-terminal OB domain ABC2_membrane PF01061.24 KXZ43196.1 - 0.037 13.4 1.8 0.07 12.5 1.8 1.4 1 0 0 1 1 1 0 ABC-2 type transporter Calponin PF00402.18 KXZ43196.1 - 0.075 12.7 42.7 42 3.9 0.0 15.1 16 0 0 16 16 16 0 Calponin family repeat ABC_trans_aux PF03886.13 KXZ43197.1 - 0.023 14.3 0.7 0.083 12.5 0.7 1.8 1 1 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component Ank_2 PF12796.7 KXZ43198.1 - 5e-108 353.9 30.0 1.7e-18 66.9 0.1 6.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43198.1 - 3.3e-87 285.8 13.9 5.2e-11 42.9 0.1 10.1 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43198.1 - 2.5e-74 236.3 1.8 0.0012 19.1 0.0 13.7 14 0 0 14 14 14 13 Ankyrin repeat Ank PF00023.30 KXZ43198.1 - 3.9e-71 232.6 26.6 5.9e-05 23.3 0.1 14.0 13 1 1 14 14 14 13 Ankyrin repeat Ank_5 PF13857.6 KXZ43198.1 - 1.4e-56 187.8 28.8 1.3e-09 38.2 0.2 11.8 1 1 13 14 14 14 14 Ankyrin repeats (many copies) GATase_7 PF13537.6 KXZ43198.1 - 0.0014 18.5 0.3 56 3.7 0.0 6.7 6 3 1 8 8 8 0 Glutamine amidotransferase domain BHD_2 PF10404.9 KXZ43198.1 - 0.01 16.8 0.1 68 4.5 0.0 4.6 4 1 0 4 4 4 0 Rad4 beta-hairpin domain 2 DUF2170 PF09938.9 KXZ43198.1 - 0.17 11.6 0.0 71 3.1 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2170) DUF1593 PF07632.11 KXZ43198.1 - 0.34 10.3 9.2 72 2.7 0.0 5.7 2 2 1 6 6 6 0 Protein of unknown function (DUF1593) Calponin PF00402.18 KXZ43198.1 - 0.4 10.4 30.3 18 5.1 0.2 9.9 10 0 0 10 10 10 0 Calponin family repeat DUF1499 PF07386.11 KXZ43198.1 - 2.5 8.7 6.2 3.3e+02 1.8 0.0 4.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1499) DUF3368 PF11848.8 KXZ43198.1 - 4.1 7.3 8.6 55 3.7 0.0 5.8 7 0 0 7 7 7 0 Domain of unknown function (DUF3368) Ank_2 PF12796.7 KXZ43200.1 - 7.9e-78 257.1 18.8 1.9e-15 57.2 0.6 6.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43200.1 - 4.6e-64 210.2 22.0 2e-07 31.1 0.0 11.2 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 KXZ43200.1 - 5.5e-61 202.2 5.9 1.1e-10 41.8 0.1 9.1 6 2 3 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43200.1 - 1.6e-58 187.7 6.8 1.9e-05 24.7 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 KXZ43200.1 - 6.2e-45 150.7 28.1 1.4e-09 38.0 1.2 10.4 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Sulfotransfer_4 PF17784.1 KXZ43200.1 - 5e-07 29.8 0.0 0.4 10.5 0.0 3.7 1 1 2 3 3 3 3 Sulfotransferase domain Zwint PF15556.6 KXZ43200.1 - 0.0033 17.0 0.9 2.9 7.3 0.0 3.3 1 1 1 3 3 3 2 ZW10 interactor DUF1604 PF07713.13 KXZ43200.1 - 0.26 11.1 4.5 27 4.7 0.1 4.4 6 1 0 6 6 6 0 Protein of unknown function (DUF1604) PQQ_3 PF13570.6 KXZ43200.1 - 0.54 10.8 8.6 8.7 7.0 0.6 4.3 3 2 0 3 3 3 0 PQQ-like domain TetR_C_6 PF13977.6 KXZ43200.1 - 0.72 10.1 8.4 3.3 7.9 0.2 4.4 2 1 3 5 5 5 0 BetI-type transcriptional repressor, C-terminal MIF4G PF02854.19 KXZ43201.1 - 2.1e-14 53.7 0.1 3.3e-14 53.1 0.1 1.5 1 1 0 1 1 1 1 MIF4G domain Ank_2 PF12796.7 KXZ43202.1 - 1.4e-155 506.3 56.1 9.9e-18 64.5 0.1 8.1 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43202.1 - 3e-89 292.3 17.5 7.1e-10 39.2 0.1 10.0 4 3 7 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43202.1 - 3.8e-85 276.9 32.2 1.1e-06 28.8 0.0 15.9 16 0 0 16 16 16 14 Ankyrin repeat Ank_3 PF13606.6 KXZ43202.1 - 2.2e-84 267.2 10.5 3.3e-05 23.9 0.0 15.5 16 0 0 16 16 16 14 Ankyrin repeat Ank_5 PF13857.6 KXZ43202.1 - 1.6e-65 216.3 36.2 4.4e-09 36.4 0.1 12.8 1 1 13 14 14 14 14 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ43202.1 - 0.06 13.0 30.1 1.2e+02 2.5 0.0 11.2 12 0 0 12 12 12 0 Calponin family repeat Secretin_N PF03958.17 KXZ43202.1 - 0.087 13.2 1.9 69 3.9 1.9 4.8 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain DUF3368 PF11848.8 KXZ43202.1 - 5.3 6.9 7.0 1.2e+02 2.6 0.2 5.4 6 0 0 6 6 6 0 Domain of unknown function (DUF3368) Ank_2 PF12796.7 KXZ43204.1 - 1.7e-102 336.2 59.3 1.1e-20 74.0 2.4 8.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43204.1 - 7.5e-80 262.4 23.3 3.8e-12 46.5 0.0 10.2 6 3 2 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43204.1 - 5.6e-75 244.8 48.5 1.2e-06 28.7 0.1 15.6 15 1 0 15 15 15 12 Ankyrin repeat Ank_3 PF13606.6 KXZ43204.1 - 2.8e-73 233.1 21.2 8.6e-05 22.7 0.0 15.2 14 1 1 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 KXZ43204.1 - 1.4e-61 203.7 45.4 7.5e-09 35.7 0.1 13.4 2 2 12 14 14 14 13 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ43204.1 - 0.013 15.1 17.2 1.1e+02 2.6 0.0 8.8 9 0 0 9 9 9 0 Calponin family repeat Sulfotransfer_4 PF17784.1 KXZ43204.1 - 0.1 12.4 0.2 5.9 6.7 0.0 3.7 4 1 1 5 5 5 0 Sulfotransferase domain DUF3368 PF11848.8 KXZ43204.1 - 0.39 10.5 11.0 34 4.3 0.0 6.9 10 0 0 10 10 10 0 Domain of unknown function (DUF3368) Secretin_N PF03958.17 KXZ43204.1 - 2.2 8.7 11.8 36 4.9 1.1 5.0 2 2 0 2 2 2 0 Bacterial type II/III secretion system short domain DUF1499 PF07386.11 KXZ43204.1 - 9.3 6.8 11.5 2.1e+02 2.5 1.2 5.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1499) Ank_2 PF12796.7 KXZ43205.1 - 4.5e-78 257.9 25.1 6e-19 68.4 0.8 5.4 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43205.1 - 8.2e-60 198.5 10.4 3.2e-13 49.9 0.0 5.7 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43205.1 - 4.6e-53 175.5 18.7 1.1e-06 28.8 0.1 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 KXZ43205.1 - 9.8e-53 170.0 2.3 2.6e-05 24.3 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 KXZ43205.1 - 5e-46 154.2 17.1 1.4e-09 38.0 0.0 7.4 3 2 3 7 7 7 7 Ankyrin repeats (many copies) DUF2384 PF09722.10 KXZ43205.1 - 0.056 13.5 1.2 20 5.3 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) UBA PF00627.31 KXZ43205.1 - 0.15 12.0 23.8 8.1 6.5 0.3 6.9 7 0 0 7 7 7 0 UBA/TS-N domain Calponin PF00402.18 KXZ43205.1 - 0.21 11.3 4.4 7 6.4 0.3 3.8 3 0 0 3 3 3 0 Calponin family repeat PdxA PF04166.12 KXZ43205.1 - 0.22 10.9 7.1 0.3 10.5 3.4 2.4 2 1 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA RVP PF00077.20 KXZ43205.1 - 0.27 11.5 0.8 6.9 7.1 0.1 3.5 3 2 2 5 5 5 0 Retroviral aspartyl protease RVT_1 PF00078.27 KXZ43206.1 - 8.4e-22 77.8 0.0 9.5e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 KXZ43207.1 - 3.9e-135 440.8 40.4 1.2e-13 51.4 0.8 12.2 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43207.1 - 9.3e-110 354.7 70.3 1.2e-06 28.7 0.1 25.0 24 1 1 25 25 25 23 Ankyrin repeat Ank_4 PF13637.6 KXZ43207.1 - 3e-109 356.1 36.4 4.2e-09 36.8 0.0 16.6 5 3 15 20 20 20 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43207.1 - 3.2e-98 309.7 29.2 8.4e-05 22.7 0.0 24.2 25 0 0 25 25 25 20 Ankyrin repeat Ank_5 PF13857.6 KXZ43207.1 - 1.9e-85 279.8 52.3 1.1e-07 32.0 0.0 19.3 6 5 16 22 22 22 21 Ankyrin repeats (many copies) GATase_7 PF13537.6 KXZ43207.1 - 0.0021 18.0 0.0 1.3e+02 2.5 0.0 6.6 7 1 2 9 9 9 0 Glutamine amidotransferase domain DUF4988 PF16378.5 KXZ43207.1 - 0.29 10.8 2.2 65 3.1 0.0 5.0 4 2 2 6 6 6 0 Domain of unknown function Beta_helix PF13229.6 KXZ43208.1 - 1.5e-06 28.1 21.7 0.00025 20.9 1.5 3.8 1 1 3 4 4 4 3 Right handed beta helix region Kelch_3 PF13415.6 KXZ43208.1 - 2.2e-06 27.8 2.7 4.3e-05 23.7 0.2 4.5 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.6 KXZ43208.1 - 1.6e-05 24.8 0.8 0.00081 19.3 0.1 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ43208.1 - 0.0019 18.1 9.8 0.0021 18.0 0.5 4.6 6 0 0 6 6 6 1 Kelch motif Ephrin_rec_like PF07699.13 KXZ43208.1 - 0.004 16.9 6.8 0.017 14.9 6.8 2.1 1 0 0 1 1 1 1 Putative ephrin-receptor like TRP PF06011.12 KXZ43208.1 - 0.015 14.1 4.4 0.029 13.1 4.4 1.4 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Kelch_6 PF13964.6 KXZ43208.1 - 0.022 15.0 6.0 0.24 11.8 0.4 4.7 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.25 KXZ43208.1 - 0.18 11.4 1.8 1.1 8.9 0.3 3.3 3 0 0 3 3 3 0 Kelch motif DUF5123 PF17161.4 KXZ43208.1 - 0.4 11.8 1.5 1.1 10.3 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF5123) Kelch_2 PF07646.15 KXZ43208.1 - 1.4 9.0 8.9 1.5 8.9 0.5 4.3 4 0 0 4 4 4 0 Kelch motif MSC PF09402.10 KXZ43208.1 - 2.1 7.7 2.9 3.8 6.9 2.9 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Kelch_5 PF13854.6 KXZ43209.1 - 3.9e-12 45.9 2.8 0.04 13.9 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KXZ43209.1 - 5.8e-10 39.2 8.8 5.5e-06 26.5 0.1 5.6 5 2 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ43209.1 - 1.7e-09 37.6 4.0 0.032 14.5 0.1 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KXZ43209.1 - 7.4e-08 31.9 2.7 0.00029 20.4 0.1 3.8 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KXZ43209.1 - 4.8e-06 26.5 12.0 0.0011 18.9 0.2 4.9 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KXZ43209.1 - 0.0016 18.3 5.0 7.4 6.7 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Pkinase_Tyr PF07714.17 KXZ43210.1 - 1.1e-40 139.6 0.0 1.6e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ43210.1 - 1.9e-40 138.9 0.0 8.8e-40 136.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ43210.1 - 0.00067 18.5 0.0 0.00097 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ43210.1 - 0.009 16.0 0.0 0.055 13.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3188 PF11384.8 KXZ43210.1 - 0.026 14.2 0.4 0.078 12.7 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF4448 PF14610.6 KXZ43210.1 - 0.039 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) tRNA_synthFbeta PF17759.1 KXZ43211.1 - 1.5e-48 165.1 0.0 2.4e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KXZ43211.1 - 1.5e-35 121.3 0.1 6e-35 119.3 0.0 2.0 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KXZ43211.1 - 2.8e-27 95.5 0.0 5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KXZ43211.1 - 9.5e-18 64.3 0.0 5.5e-16 58.6 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 KXZ43211.1 - 0.031 13.8 0.0 0.18 11.2 0.0 2.0 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) CdvA PF18822.1 KXZ43212.1 - 0.074 12.9 0.2 0.074 12.9 0.2 2.7 4 0 0 4 4 4 0 CdvA-like coiled-coil domain TPR_MLP1_2 PF07926.12 KXZ43212.1 - 0.11 12.6 39.0 0.47 10.5 2.0 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 KXZ43212.1 - 0.53 10.4 11.5 17 5.5 0.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 KXZ43212.1 - 3.8 7.4 11.4 4.9 7.0 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_13 PF13166.6 KXZ43212.1 - 4.3 5.8 9.0 0.36 9.4 4.5 1.4 2 0 0 2 2 2 0 AAA domain Fez1 PF06818.15 KXZ43212.1 - 4.8 7.6 21.8 2.6e+02 1.9 3.0 2.3 1 1 1 2 2 2 0 Fez1 DUF966 PF06136.13 KXZ43212.1 - 6.1 6.5 8.0 7.7 6.1 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4407 PF14362.6 KXZ43212.1 - 8.7 5.6 36.0 2 7.7 26.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PDEase_I PF00233.19 KXZ43213.1 - 3.6e-72 242.9 7.0 5.6e-72 242.3 7.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KXZ43213.1 - 1e-23 84.4 0.2 6.3e-15 56.0 0.0 2.8 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KXZ43213.1 - 1.1e-13 51.6 0.3 2.6e-07 31.0 0.0 3.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KXZ43213.1 - 0.00097 19.5 0.2 0.018 15.4 0.0 3.0 3 1 0 3 3 3 1 GAF domain HD PF01966.22 KXZ43213.1 - 0.04 14.1 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 HD domain Sod_Fe_C PF02777.18 KXZ43214.1 - 1.1e-37 128.3 0.6 2e-37 127.4 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXZ43214.1 - 1.1e-32 112.3 1.0 2.1e-32 111.4 1.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_M11 PF05548.11 KXZ43216.1 - 3.7e-61 207.0 0.1 5e-61 206.6 0.1 1.0 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_5 PF13688.6 KXZ43216.1 - 0.074 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KXZ43216.1 - 0.099 11.6 1.2 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase M66 Reprolysin_3 PF13582.6 KXZ43216.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Aldedh PF00171.22 KXZ43217.1 - 2.8e-168 560.2 0.0 3.1e-168 560.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TIL PF01826.17 KXZ43217.1 - 0.089 13.1 2.5 0.23 11.8 2.5 1.6 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF4407 PF14362.6 KXZ43218.1 - 1.3 8.3 30.6 1.2 8.4 26.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HSA PF07529.13 KXZ43219.1 - 0.00017 21.8 0.2 0.00017 21.8 0.2 2.1 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.6 KXZ43219.1 - 0.0035 17.6 0.1 0.0076 16.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXZ43219.1 - 0.0065 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXZ43219.1 - 0.073 13.5 0.7 0.16 12.4 0.1 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 KXZ43220.1 - 4.7e-39 134.3 0.0 1.8e-28 99.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43220.1 - 2.7e-38 131.7 0.0 3.2e-28 98.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ43220.1 - 0.048 13.0 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4431 PF14485.6 KXZ43220.1 - 1.2 9.0 2.6 0.78 9.6 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) LapA_dom PF06305.11 KXZ43221.1 - 1.5 8.6 4.9 3.4 7.6 0.2 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-RING_2 PF13639.6 KXZ43222.1 - 1.8e-07 31.4 7.4 2.9e-07 30.7 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXZ43222.1 - 7.6e-06 25.7 7.9 1.2e-05 25.0 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ43222.1 - 8.2e-05 22.4 7.8 0.00014 21.6 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXZ43222.1 - 0.00027 20.9 1.7 0.00069 19.6 1.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXZ43222.1 - 0.00099 19.2 7.8 0.0024 18.0 7.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXZ43222.1 - 0.0014 18.4 5.4 0.0029 17.3 5.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KXZ43222.1 - 0.0025 17.8 1.0 0.0025 17.8 1.0 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ43222.1 - 0.0036 17.2 5.9 0.0077 16.2 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXZ43222.1 - 0.046 14.0 9.9 0.32 11.3 9.9 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXZ43222.1 - 0.14 11.9 7.7 0.33 10.7 7.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 KXZ43222.1 - 1.4 8.8 8.2 2.9 7.8 8.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KXZ43222.1 - 2.4 8.1 5.0 4.4 7.2 4.6 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein CDP-OH_P_transf PF01066.21 KXZ43223.1 - 1.4e-14 54.6 1.8 1.7e-14 54.3 0.2 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Phage_Coat_B PF05356.11 KXZ43223.1 - 0.59 10.1 2.4 0.7 9.8 0.1 2.1 2 0 0 2 2 2 0 Phage Coat protein B Peptidase_M24 PF00557.24 KXZ43224.1 - 1.5e-24 86.9 0.5 1.8e-24 86.6 0.5 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SMAP PF15477.6 KXZ43225.1 - 1.4e-13 51.6 0.1 1.4e-13 51.6 0.1 2.0 2 1 0 2 2 2 1 Small acidic protein family LRR_4 PF12799.7 KXZ43227.1 - 7.6e-09 35.7 9.5 9.5e-06 25.9 2.9 3.2 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXZ43227.1 - 1.4e-07 31.2 0.0 2.3e-06 27.2 0.0 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KXZ43227.1 - 3.5e-07 29.9 20.5 3.5e-05 23.5 8.1 3.1 1 1 4 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 KXZ43227.1 - 0.0012 18.7 4.6 0.33 11.1 0.4 3.9 2 1 1 3 3 3 1 Leucine Rich repeat Kei1 PF08552.11 KXZ43227.1 - 0.5 10.2 1.2 1.1 9.0 1.2 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LRR_1 PF00560.33 KXZ43227.1 - 0.82 10.5 5.9 22 6.1 2.0 3.4 2 1 0 2 2 2 0 Leucine Rich Repeat Beta_helix PF13229.6 KXZ43228.1 - 7.2e-06 25.9 0.2 0.33 10.8 0.0 3.8 2 1 2 4 4 4 4 Right handed beta helix region Ank_2 PF12796.7 KXZ43229.1 - 8.2e-11 42.4 0.1 0.015 15.9 0.1 4.0 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43229.1 - 5e-08 33.3 2.6 0.63 10.7 0.1 5.7 2 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43229.1 - 0.0098 16.2 7.7 15 6.1 0.1 5.8 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43229.1 - 0.021 15.3 3.7 84 4.3 0.0 6.9 10 0 0 10 10 10 0 Ankyrin repeat DEAD PF00270.29 KXZ43232.1 - 1.2e-47 162.0 0.0 3.6e-47 160.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ43232.1 - 6.1e-32 110.3 0.0 1.5e-30 105.8 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXZ43232.1 - 0.00072 18.8 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KXZ43232.1 - 0.00081 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit CAAD PF14159.6 KXZ43233.1 - 5.9e-19 67.7 0.0 9.1e-19 67.1 0.0 1.2 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Unstab_antitox PF09720.10 KXZ43233.1 - 0.3 11.2 5.7 7.7 6.7 0.2 2.7 2 1 0 2 2 2 0 Putative addiction module component Actin PF00022.19 KXZ43235.1 - 1.7e-150 501.2 0.0 6.5e-150 499.3 0.0 1.7 1 1 0 1 1 1 1 Actin RRM_1 PF00076.22 KXZ43236.1 - 4.7e-20 71.2 0.1 6.5e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.19 KXZ43236.1 - 4 8.1 8.7 31 5.2 0.4 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-met PF12874.7 KXZ43237.1 - 0.0028 18.0 0.3 0.0048 17.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXZ43237.1 - 0.049 13.9 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding HALZ PF02183.18 KXZ43239.1 - 0.23 11.7 0.2 0.47 10.7 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper G10 PF01125.17 KXZ43240.1 - 3.2e-50 169.7 0.4 4.2e-50 169.3 0.4 1.2 1 0 0 1 1 1 1 G10 protein zf-RING_2 PF13639.6 KXZ43241.1 - 1.8e-08 34.6 5.8 1e-07 32.1 0.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXZ43241.1 - 5.9e-08 32.9 2.1 1.5e-07 31.6 0.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXZ43241.1 - 1.1e-06 28.3 1.3 2.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXZ43241.1 - 4.5e-05 23.1 4.6 0.00048 19.8 0.1 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KXZ43241.1 - 0.00048 20.0 2.4 0.0085 16.0 0.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXZ43241.1 - 0.0014 18.6 1.8 0.0042 17.1 0.3 2.0 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KXZ43241.1 - 0.0041 16.9 3.1 0.0041 16.9 3.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ43241.1 - 0.017 14.9 2.8 0.046 13.6 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ43241.1 - 0.025 14.4 0.3 0.025 14.4 0.3 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXZ43241.1 - 0.027 14.6 0.2 0.027 14.6 0.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXZ43241.1 - 0.028 14.1 0.2 0.028 14.1 0.2 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXZ43241.1 - 0.039 14.1 1.7 0.039 14.1 1.7 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 KXZ43241.1 - 0.04 14.0 0.3 0.04 14.0 0.3 2.5 2 1 0 2 2 2 0 RING-type zinc-finger zf-MIZ PF02891.20 KXZ43241.1 - 0.04 13.7 0.7 0.04 13.7 0.7 1.7 2 0 0 2 2 1 0 MIZ/SP-RING zinc finger DUF2795 PF11387.8 KXZ43241.1 - 0.082 13.1 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) FATC PF02260.20 KXZ43242.1 - 1e-07 31.7 0.2 1.4e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 FATC domain CDC37_N PF03234.14 KXZ43245.1 - 0.36 11.7 4.7 0.58 11.1 4.7 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Lactamase_B_3 PF13483.6 KXZ43246.1 - 1.5e-20 73.8 0.0 2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Topoisom_bac PF01131.20 KXZ43247.1 - 1e-54 186.1 0.0 2.3e-31 109.2 0.0 2.2 1 1 0 2 2 2 2 DNA topoisomerase Toprim_C_rpt PF13368.6 KXZ43247.1 - 4.1e-26 90.7 10.7 2.5e-14 53.0 0.0 3.5 2 1 0 2 2 2 2 Topoisomerase C-terminal repeat HMG_box PF00505.19 KXZ43247.1 - 7.2e-18 64.8 0.1 1.4e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KXZ43247.1 - 1.8e-12 47.7 0.4 3.7e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 HMG-box domain Toprim PF01751.22 KXZ43247.1 - 4e-09 36.6 0.0 1.1e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 KXZ43247.1 - 1.1e-07 31.4 1.2 2.2e-07 30.5 1.2 1.5 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger CHDNT PF08073.12 KXZ43247.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 KXZ43247.1 - 0.097 13.2 0.5 0.22 12.1 0.5 1.5 1 0 0 1 1 1 0 YABBY protein S1FA PF04689.13 KXZ43247.1 - 3 8.1 4.0 7 6.9 4.0 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA DUF3584 PF12128.8 KXZ43248.1 - 0.12 9.8 23.5 0.38 8.2 8.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Jnk-SapK_ap_N PF09744.9 KXZ43248.1 - 1.7 8.8 14.7 0.7 10.1 2.1 2.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 KXZ43248.1 - 2.6 8.5 16.3 2.4 8.6 4.4 2.1 1 1 1 2 2 2 0 Fez1 Lectin_N PF03954.14 KXZ43248.1 - 3.9 7.2 6.8 2.7 7.7 1.8 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CENP-F_leu_zip PF10473.9 KXZ43248.1 - 4.2 7.4 11.1 3.5 7.7 2.0 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 KXZ43248.1 - 6.1 6.5 10.0 8.3 6.0 1.3 2.9 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Phage_GP20 PF06810.11 KXZ43248.1 - 6.1 6.6 12.9 1.6 8.5 0.4 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 AAA_12 PF13087.6 KXZ43249.1 - 1.9e-57 194.1 0.0 3.2e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ43249.1 - 1.2e-55 189.2 0.5 3.2e-55 187.7 0.5 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXZ43249.1 - 3.3e-11 43.3 7.4 3.8e-10 39.8 6.1 2.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ43249.1 - 1.5e-08 34.7 0.0 0.11 12.3 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KXZ43249.1 - 1.3e-06 28.8 0.7 1.7e-05 25.2 0.5 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXZ43249.1 - 4.8e-05 23.6 0.1 0.017 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KXZ43249.1 - 0.00026 20.3 1.9 0.47 9.6 0.0 2.8 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KXZ43249.1 - 0.0019 18.6 0.0 0.0057 17.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 KXZ43249.1 - 0.002 18.0 0.2 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KXZ43249.1 - 0.0097 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXZ43249.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Zot PF05707.12 KXZ43249.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_25 PF13481.6 KXZ43249.1 - 0.018 14.6 0.1 0.045 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ43249.1 - 0.019 15.3 8.1 0.068 13.5 6.8 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KXZ43249.1 - 0.022 14.9 0.9 0.095 12.9 0.2 2.6 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 KXZ43249.1 - 0.024 14.4 0.2 0.1 12.3 0.2 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase DnaB_C PF03796.15 KXZ43249.1 - 0.024 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 KXZ43249.1 - 0.03 13.4 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KXZ43249.1 - 0.052 13.0 0.4 1.1 8.6 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein Glyco_tranf_2_3 PF13641.6 KXZ43249.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 RuvB_N PF05496.12 KXZ43249.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KXZ43249.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PIF1 PF05970.14 KXZ43249.1 - 0.17 11.0 0.0 0.92 8.6 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase VCX_VCY PF15231.6 KXZ43249.1 - 0.23 12.1 13.1 0.069 13.8 9.0 2.2 2 0 0 2 2 2 0 Variable charge X/Y family DUF2786 PF10979.8 KXZ43249.1 - 0.28 11.1 0.1 0.28 11.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) DUF485 PF04341.12 KXZ43250.1 - 0.014 15.3 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Pkinase_fungal PF17667.1 KXZ43251.1 - 2.1e-05 23.5 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KXZ43251.1 - 2.9e-05 23.6 0.0 9.1e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KXZ43251.1 - 0.005 16.2 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ43251.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TIP49 PF06068.13 KXZ43252.1 - 9.8e-148 492.0 9.2 1.6e-145 484.8 9.2 2.1 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXZ43252.1 - 3e-27 94.5 0.8 7.1e-27 93.3 0.8 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXZ43252.1 - 1.4e-09 38.5 2.7 3.9e-06 27.3 0.2 3.3 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXZ43252.1 - 4.1e-07 29.9 1.0 0.00082 19.1 0.2 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXZ43252.1 - 7.2e-07 29.3 0.5 0.00047 20.2 0.1 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 KXZ43252.1 - 2.9e-06 26.8 0.4 5.3e-06 26.0 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 KXZ43252.1 - 8.2e-06 26.2 2.4 5.2e-05 23.6 2.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ43252.1 - 1.6e-05 25.2 0.3 0.062 13.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KXZ43252.1 - 6.9e-05 22.3 2.2 0.0026 17.2 1.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ43252.1 - 0.00025 21.5 0.2 0.00096 19.6 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 KXZ43252.1 - 0.0009 19.0 0.8 1.1 8.9 0.2 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_25 PF13481.6 KXZ43252.1 - 0.0022 17.6 0.1 0.0051 16.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KXZ43252.1 - 0.0033 16.8 0.1 0.007 15.7 0.1 1.7 1 0 0 1 1 1 1 KaiC Zeta_toxin PF06414.12 KXZ43252.1 - 0.0058 15.9 0.7 0.017 14.4 0.6 1.8 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 KXZ43252.1 - 0.0084 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ResIII PF04851.15 KXZ43252.1 - 0.0092 16.0 0.3 0.11 12.4 0.3 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KXZ43252.1 - 0.01 15.4 0.1 0.045 13.3 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXZ43252.1 - 0.031 14.0 2.2 0.33 10.6 0.7 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXZ43252.1 - 0.032 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 KXZ43252.1 - 0.076 13.0 2.0 0.1 12.6 0.4 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-RING_11 PF17123.5 KXZ43253.1 - 1.5e-05 24.6 4.6 2.8e-05 23.8 4.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXZ43253.1 - 2.1e-05 24.8 4.2 3.4e-05 24.1 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXZ43253.1 - 0.48 10.5 5.7 0.89 9.6 5.7 1.4 1 0 0 1 1 1 0 RING-type zinc-finger ABC_tran PF00005.27 KXZ43254.1 - 5.1e-31 108.0 0.0 8.6e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXZ43254.1 - 2.5e-30 106.0 3.9 1.6e-28 100.1 3.9 2.6 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KXZ43254.1 - 3.6e-06 26.6 0.3 8.9e-05 22.0 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXZ43254.1 - 0.0013 19.0 0.3 0.02 15.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ43254.1 - 0.0031 17.9 0.7 0.02 15.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KXZ43254.1 - 0.014 15.5 0.2 0.024 14.7 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 KXZ43254.1 - 0.019 14.1 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KXZ43254.1 - 0.031 13.6 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KXZ43254.1 - 0.034 13.9 2.2 0.074 12.8 0.5 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.29 KXZ43254.1 - 0.057 13.2 0.2 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 KXZ43254.1 - 0.087 12.9 0.0 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 KXZ43254.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Adap_comp_sub PF00928.21 KXZ43255.1 - 1.8e-31 109.5 0.0 2.6e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXZ43255.1 - 1.1e-06 28.6 0.1 1.9e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RE_HindIII PF09518.10 KXZ43255.1 - 0.029 13.6 1.3 0.042 13.1 1.3 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease IFT20 PF14931.6 KXZ43256.1 - 5.7e-24 84.6 16.6 6.3e-24 84.4 16.6 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 ISG65-75 PF11727.8 KXZ43256.1 - 0.071 12.3 4.5 0.073 12.3 4.5 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein KIAA1430 PF13879.6 KXZ43256.1 - 0.091 13.5 6.5 0.69 10.7 6.5 2.1 1 1 0 1 1 1 0 KIAA1430 homologue YlqD PF11068.8 KXZ43256.1 - 0.32 11.4 14.2 0.42 11.0 14.2 1.3 1 0 0 1 1 1 0 YlqD protein Folliculin PF11704.8 KXZ43256.1 - 0.57 10.0 5.8 0.67 9.8 5.8 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ZYG-11_interact PF05884.12 KXZ43256.1 - 0.95 8.8 3.4 1.2 8.5 3.4 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 TMPIT PF07851.13 KXZ43256.1 - 4.5 6.4 8.8 5.3 6.2 8.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein GBP_C PF02841.14 KXZ43256.1 - 8.1 5.8 16.2 23 4.3 16.2 1.7 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SCAMP PF04144.13 KXZ43257.1 - 5.3e-05 23.6 0.0 6.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 SCAMP family GAIN_A PF18619.1 KXZ43257.1 - 0.085 13.1 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A SCAMP PF04144.13 KXZ43258.1 - 4.2e-25 89.0 10.7 6.4e-25 88.4 10.7 1.2 1 0 0 1 1 1 1 SCAMP family Rtt106 PF08512.12 KXZ43258.1 - 1.5e-18 67.0 0.0 1.2e-17 64.1 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like NOA36 PF06524.12 KXZ43258.1 - 0.29 10.4 7.7 0.058 12.7 4.1 1.6 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 KXZ43259.1 - 0.5 8.4 33.2 0.57 8.2 33.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi FRQ PF09421.10 KXZ43259.1 - 1.6 6.6 13.0 1.9 6.4 13.0 1.0 1 0 0 1 1 1 0 Frequency clock protein DTHCT PF08070.11 KXZ43259.1 - 5.1 7.9 13.9 1.5 9.6 8.0 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region BSP_II PF05432.11 KXZ43259.1 - 5.5 6.6 20.6 6.2 6.4 20.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 KXZ43259.1 - 5.7 5.1 14.4 6 5.0 14.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 KXZ43259.1 - 7.6 5.6 8.8 11 5.2 8.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CPBP PF02517.16 KXZ43260.1 - 1.1e-13 51.3 1.4 1.1e-13 51.3 1.4 1.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease TPR_1 PF00515.28 KXZ43261.1 - 2.6e-18 65.0 8.5 0.00038 20.2 0.2 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ43261.1 - 2.6e-14 52.1 17.4 0.0033 17.4 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ43261.1 - 4.4e-10 39.1 4.8 0.00042 19.9 0.1 4.9 3 1 1 4 4 4 3 TPR repeat TPR_9 PF13371.6 KXZ43261.1 - 2e-07 31.0 18.1 0.0066 16.6 1.0 5.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ43261.1 - 3.1e-06 27.2 6.3 0.04 14.3 0.5 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ43261.1 - 2.3e-05 24.2 5.4 9.2 6.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ43261.1 - 0.00025 20.9 4.4 3.4 7.9 0.2 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat SCNM1_acidic PF15805.5 KXZ43261.1 - 0.027 14.2 0.2 0.027 14.2 0.2 2.1 2 0 0 2 2 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 TPR_19 PF14559.6 KXZ43261.1 - 0.039 14.5 19.0 0.59 10.7 0.0 5.0 3 2 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KXZ43261.1 - 0.057 13.5 3.5 15 5.8 0.1 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KXZ43261.1 - 1.2 10.1 0.0 1.2 10.1 0.0 8.1 6 1 3 9 9 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ43261.1 - 2.2 8.7 27.8 6.4 7.1 0.4 6.6 5 1 1 7 7 6 0 Tetratricopeptide repeat HHH_8 PF14716.6 KXZ43261.1 - 7.9 6.9 10.8 30 5.1 0.1 4.2 5 0 0 5 5 4 0 Helix-hairpin-helix domain TPR_1 PF00515.28 KXZ43262.1 - 5.9e-16 57.5 11.3 0.00014 21.6 0.2 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ43262.1 - 6.8e-16 57.0 22.0 0.00042 20.2 0.6 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ43262.1 - 6.1e-12 44.8 6.7 0.004 17.2 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat RPAP3_C PF13877.6 KXZ43262.1 - 3e-11 43.7 0.0 5.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.6 KXZ43262.1 - 3.5e-08 33.0 4.1 0.36 10.5 0.0 4.7 4 0 0 4 4 4 3 TPR repeat TPR_19 PF14559.6 KXZ43262.1 - 6.5e-07 29.8 24.2 0.0033 17.9 2.7 5.4 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ43262.1 - 9.5e-07 29.1 31.1 0.0002 21.9 1.5 7.2 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ43262.1 - 0.00015 22.0 32.9 0.49 10.7 8.3 6.0 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ43262.1 - 0.0015 19.1 18.7 0.0048 17.5 5.4 7.5 6 1 2 8 8 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ43262.1 - 0.0022 18.3 4.0 5.6 7.6 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 KXZ43262.1 - 0.039 14.0 3.5 6.4 6.8 0.0 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 KXZ43262.1 - 0.34 11.6 0.1 0.34 11.6 0.1 5.6 6 1 0 6 6 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ43262.1 - 1.3 9.2 8.2 1.8 8.8 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ43262.1 - 1.9 8.7 19.5 0.61 10.3 2.5 4.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ43262.1 - 5.1 7.1 25.7 0.94 9.4 0.9 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Lebercilin PF15619.6 KXZ43263.1 - 0.002 17.8 21.4 0.002 17.8 21.4 2.5 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease SHE3 PF17078.5 KXZ43263.1 - 0.0059 16.4 14.5 0.28 10.8 8.8 3.0 2 1 0 2 2 2 2 SWI5-dependent HO expression protein 3 GAS PF13851.6 KXZ43263.1 - 0.048 13.0 33.6 0.034 13.5 11.0 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 KXZ43263.1 - 0.35 10.9 10.7 0.3 11.1 0.7 3.2 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 KXZ43263.1 - 0.46 10.3 26.0 0.79 9.5 2.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) SOGA PF11365.8 KXZ43263.1 - 0.64 11.2 27.6 0.87 10.8 2.4 3.7 1 1 1 3 3 3 0 Protein SOGA Spc7 PF08317.11 KXZ43263.1 - 0.65 8.8 37.6 0.32 9.8 17.8 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KXZ43263.1 - 0.66 10.5 0.1 0.66 10.5 0.1 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TnpV PF14198.6 KXZ43263.1 - 0.93 9.5 8.2 4.4 7.3 1.8 2.7 1 1 0 2 2 2 0 Transposon-encoded protein TnpV CCDC144C PF14915.6 KXZ43263.1 - 1.6 7.8 35.1 0.11 11.6 21.8 2.6 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Sec34 PF04136.15 KXZ43263.1 - 5.2 6.9 11.6 0.41 10.5 2.2 2.9 3 0 0 3 3 3 0 Sec34-like family IFT57 PF10498.9 KXZ43263.1 - 9.1 5.1 19.6 0.25 10.3 2.7 2.8 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 Ribosomal_L9_C PF03948.14 KXZ43264.1 - 3.6e-20 72.2 0.3 3.6e-20 72.2 0.3 1.8 3 0 0 3 3 3 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 KXZ43264.1 - 3.6e-15 55.2 0.0 8.6e-15 54.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Flg_hook PF02120.16 KXZ43264.1 - 0.034 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK CABS1 PF15367.6 KXZ43264.1 - 0.056 12.6 0.4 0.071 12.2 0.4 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 Ig_6 PF18452.1 KXZ43264.1 - 0.082 12.5 0.4 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain MCM_lid PF17855.1 KXZ43265.1 - 1.5e-06 28.5 0.5 2.4e-06 27.9 0.5 1.3 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KXZ43265.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain Rimk_N PF18030.1 KXZ43265.1 - 0.018 15.4 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 RimK PreATP-grasp domain Tnp_DNA_bind PF14706.6 KXZ43267.1 - 1.3 9.0 4.5 2.4 8.1 0.7 2.5 2 0 0 2 2 2 0 Transposase DNA-binding Med10 PF09748.9 KXZ43268.1 - 1.6e-18 66.9 0.0 1.9e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex CBFD_NFYB_HMF PF00808.23 KXZ43269.1 - 3.4e-16 59.3 0.6 5.3e-16 58.6 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ43269.1 - 2.1e-11 44.3 0.4 3.4e-11 43.6 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KXZ43269.1 - 0.11 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Glyco_hydro_28 PF00295.17 KXZ43270.1 - 1.7e-14 53.7 0.0 5.8e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KXZ43270.1 - 0.00083 19.2 0.0 0.0046 16.8 0.0 2.1 1 1 0 1 1 1 1 Right handed beta helix region DUF4498 PF14926.6 KXZ43271.1 - 5.3e-51 173.3 0.1 1.7e-45 155.3 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4498) TipAS PF07739.13 KXZ43271.1 - 0.13 12.8 0.1 23 5.6 0.0 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Septin PF00735.18 KXZ43272.1 - 1.1e-44 152.8 0.0 1.4e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXZ43272.1 - 0.00085 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KXZ43272.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXZ43272.1 - 0.019 14.8 0.0 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KXZ43272.1 - 0.033 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ43272.1 - 0.037 14.5 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KXZ43272.1 - 0.041 14.3 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KXZ43272.1 - 0.044 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KXZ43272.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KXZ43272.1 - 0.064 12.8 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 KXZ43272.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 KXZ43272.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.14 KXZ43272.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.22 KXZ43272.1 - 0.2 11.2 0.2 0.43 10.2 0.2 1.5 1 0 0 1 1 1 0 Ras family Nucleotid_trans PF03407.16 KXZ43274.1 - 9.3e-09 35.6 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PfkB PF00294.24 KXZ43275.1 - 1.3e-10 41.1 0.4 2e-10 40.5 0.4 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peptidase_C97 PF05903.14 KXZ43276.1 - 3.7e-19 69.1 0.1 4.4e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXZ43276.1 - 0.0027 18.0 0.0 0.0036 17.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 KXZ43276.1 - 0.024 15.0 0.5 0.034 14.5 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Osteoregulin PF07175.11 KXZ43276.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Osteoregulin Inv-AAD PF18785.1 KXZ43277.1 - 0.0091 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase DUF498 PF04430.14 KXZ43277.1 - 0.019 15.0 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) APOBEC_C PF05240.14 KXZ43277.1 - 0.066 13.2 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 APOBEC-like C-terminal domain APOBEC2 PF18772.1 KXZ43277.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 AAA_6 PF12774.7 KXZ43278.1 - 1.8e-154 513.6 0.0 3.8e-152 506.0 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ43278.1 - 1.6e-114 383.2 0.0 1.6e-114 383.2 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 KXZ43278.1 - 3.4e-77 258.0 0.0 3.8e-75 251.4 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_8 PF12780.7 KXZ43278.1 - 2.7e-61 207.1 5.2 3.1e-54 184.0 0.1 4.2 2 1 1 3 3 3 2 P-loop containing dynein motor region D4 MT PF12777.7 KXZ43278.1 - 2.5e-55 187.9 9.1 4.8e-55 187.0 9.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KXZ43278.1 - 1.2e-54 184.8 0.3 5.6e-42 143.4 0.0 3.4 1 1 1 2 2 2 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 KXZ43278.1 - 7.2e-41 139.7 0.0 1.9e-40 138.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 KXZ43278.1 - 1.1e-26 93.5 0.0 3.3e-26 91.9 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ43278.1 - 4.1e-21 75.1 0.0 2.7e-20 72.4 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain Dynein_heavy PF03028.15 KXZ43278.1 - 3.6e-18 65.8 0.0 1.5e-17 63.8 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KXZ43278.1 - 1.6e-16 60.5 0.0 0.00022 21.3 0.0 5.4 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 KXZ43278.1 - 8.1e-05 23.1 0.0 0.65 10.4 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ43278.1 - 0.00088 19.6 2.6 0.7 10.2 0.0 5.1 6 0 0 6 6 5 1 AAA domain RNA_helicase PF00910.22 KXZ43278.1 - 0.0021 18.4 0.1 2.5 8.6 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 KXZ43278.1 - 0.0023 18.3 8.0 0.96 9.8 0.0 5.8 5 0 0 5 5 4 1 AAA ATPase domain MRFAP1 PF15155.6 KXZ43278.1 - 0.016 15.7 0.4 0.016 15.7 0.4 3.7 4 0 0 4 4 3 0 MORF4 family-associated protein1 AAA_18 PF13238.6 KXZ43278.1 - 0.019 15.5 0.0 0.72 10.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXZ43278.1 - 0.034 13.2 0.1 0.17 10.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Med21 PF11221.8 KXZ43278.1 - 0.038 14.3 1.0 0.24 11.6 1.0 2.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DUF1835 PF08874.10 KXZ43278.1 - 0.12 12.6 0.0 0.49 10.6 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) FtsK_SpoIIIE PF01580.18 KXZ43278.1 - 0.16 11.3 2.0 6.4 6.0 0.0 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family DUF87 PF01935.17 KXZ43278.1 - 0.21 11.6 0.3 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KXZ43278.1 - 0.34 10.6 5.1 11 5.7 0.2 3.6 4 0 0 4 4 2 0 AAA domain Dynein_C PF18199.1 KXZ43279.1 - 3.5e-78 262.9 0.0 1.4e-77 260.9 0.0 1.7 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain Pkinase PF00069.25 KXZ43280.1 - 3.2e-58 197.2 0.1 4.3e-58 196.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43280.1 - 3e-40 138.1 0.1 4.4e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43280.1 - 5.6e-05 22.1 3.5 0.0049 15.7 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 KXZ43280.1 - 0.00015 21.2 0.0 0.0008 18.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like CDC45 PF02724.14 KXZ43280.1 - 0.43 8.8 9.2 0.66 8.2 9.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF5401 PF17380.2 KXZ43280.1 - 0.56 8.2 35.8 0.87 7.6 35.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Presenilin PF01080.17 KXZ43280.1 - 8.9 5.0 9.9 13 4.5 9.9 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpb6 PF01192.22 KXZ43283.1 - 5.4e-18 64.7 0.1 7.9e-18 64.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 His_Phos_2 PF00328.22 KXZ43285.1 - 1.1e-08 34.9 0.0 0.0086 15.5 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) DUF1168 PF06658.12 KXZ43285.1 - 0.35 10.7 0.3 0.57 10.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) C2 PF00168.30 KXZ43286.1 - 7.2e-06 26.2 0.1 0.00047 20.4 0.1 2.3 1 1 0 1 1 1 1 C2 domain Peptidase_M99_m PF17130.4 KXZ43288.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 TruB_N PF01509.18 KXZ43289.1 - 1.1e-11 45.3 0.0 1.9e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXZ43289.1 - 2.7e-09 37.0 0.3 4.7e-09 36.3 0.3 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PDZ PF00595.24 KXZ43290.1 - 6e-05 23.3 0.1 9.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KXZ43290.1 - 0.00025 20.8 0.8 0.00025 20.8 0.8 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KXZ43290.1 - 0.0025 18.1 0.1 0.0035 17.6 0.1 1.4 1 1 0 1 1 1 1 PDZ domain DUF3394 PF11874.8 KXZ43290.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) zf-CCHC_6 PF15288.6 KXZ43292.1 - 0.018 14.9 1.6 0.054 13.3 1.6 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KXZ43292.1 - 0.18 11.6 0.8 0.5 10.2 0.5 1.8 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 KXZ43293.1 - 3.2e-25 89.0 0.0 4.2e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43293.1 - 2e-19 69.9 0.0 2.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ43293.1 - 0.0021 17.5 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ43293.1 - 0.012 15.6 1.0 0.021 14.8 0.9 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ43294.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43294.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Rubis-subs-bind PF09273.11 KXZ43296.1 - 1.9e-07 31.8 0.0 4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Presenilin PF01080.17 KXZ43297.1 - 0.37 9.5 2.7 0.44 9.3 2.7 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 KXZ43297.1 - 1.8 8.5 11.8 1.8 8.5 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_4 PF13637.6 KXZ43298.1 - 7.9e-38 128.4 1.5 1.9e-10 41.1 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43298.1 - 1.3e-35 121.8 4.3 1.5e-16 60.8 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ43298.1 - 5.3e-29 99.9 16.3 5.7e-08 32.9 1.3 6.0 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43298.1 - 6.2e-29 96.8 6.8 8.6e-05 22.7 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KXZ43298.1 - 3.1e-25 87.5 20.7 5.4e-05 23.5 0.4 7.1 7 0 0 7 7 7 6 Ankyrin repeat DUF4471 PF14740.6 KXZ43299.1 - 8.9e-71 238.6 0.0 2.1e-70 237.4 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 KXZ43299.1 - 5.4e-15 55.4 0.0 1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TFIIA PF03153.13 KXZ43300.1 - 2.4 8.1 19.2 3 7.7 19.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sulfotransfer_1 PF00685.27 KXZ43301.1 - 4.8e-09 36.1 0.0 1.6e-08 34.3 0.0 1.8 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ43301.1 - 0.00033 21.1 0.0 0.85 9.9 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Secretin_N PF03958.17 KXZ43301.1 - 0.077 13.4 4.7 0.11 12.9 0.1 3.1 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain CAP_N PF01213.19 KXZ43304.1 - 0.16 11.4 2.7 0.2 11.1 2.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF5559 PF17714.1 KXZ43304.1 - 2 8.3 7.0 0.11 12.4 1.8 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5559) Pkinase PF00069.25 KXZ43306.1 - 1e-29 103.7 0.0 1.5e-24 86.8 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43306.1 - 2.5e-24 85.9 0.0 2.4e-16 59.8 0.0 4.0 3 1 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KXZ43306.1 - 0.0048 16.9 0.8 0.02 14.8 0.7 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ43306.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ABC_membrane_2 PF06472.15 KXZ43307.1 - 1.1e-20 74.2 0.0 3e-13 49.8 0.0 2.0 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 Peptidase_M8 PF01457.16 KXZ43308.1 - 1e-37 130.0 0.0 1.2e-36 126.5 0.0 2.0 1 1 0 1 1 1 1 Leishmanolysin Protocadherin PF08374.11 KXZ43308.1 - 0.23 11.4 0.6 0.38 10.7 0.6 1.2 1 0 0 1 1 1 0 Protocadherin EGF_Tenascin PF18720.1 KXZ43308.1 - 1.1 9.4 5.3 6.3 7.0 5.3 2.4 1 0 0 1 1 1 0 Tenascin EGF domain Toxin_2 PF00451.19 KXZ43308.1 - 1.4 9.2 7.0 4.6 7.6 7.0 1.9 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 IQ PF00612.27 KXZ43309.1 - 0.39 10.6 5.6 1.1 9.2 5.6 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF5082 PF16888.5 KXZ43310.1 - 0.0037 17.5 8.1 2.3 8.5 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF5082) Spc24 PF08286.11 KXZ43310.1 - 0.034 14.4 2.1 0.57 10.4 0.4 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 KXZ43310.1 - 0.056 14.1 0.3 1.4 9.6 0.0 2.8 2 0 0 2 2 2 0 Initiation control protein YabA Med9 PF07544.13 KXZ43310.1 - 0.075 13.1 7.1 0.54 10.4 0.0 3.5 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DUF4201 PF13870.6 KXZ43310.1 - 0.11 12.3 2.2 0.13 12.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 KXZ43310.1 - 0.2 11.8 4.3 3.4 7.8 2.8 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation Jnk-SapK_ap_N PF09744.9 KXZ43310.1 - 0.35 11.1 3.9 0.71 10.1 0.9 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3251 PF11622.8 KXZ43310.1 - 0.41 10.3 4.8 0.85 9.2 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3251) APG6_N PF17675.1 KXZ43310.1 - 0.66 10.5 12.8 0.2 12.2 2.0 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KXZ43310.1 - 0.71 10.1 5.8 1.4 9.1 2.6 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.16 KXZ43310.1 - 0.94 10.0 3.5 17 5.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function DUF16 FlxA PF14282.6 KXZ43310.1 - 0.95 9.5 14.5 0.18 11.8 2.6 3.4 4 0 0 4 4 2 0 FlxA-like protein Csm1_N PF18504.1 KXZ43310.1 - 1.5 9.2 7.6 1 9.8 2.0 2.8 3 0 0 3 3 2 0 Csm1 N-terminal domain SlyX PF04102.12 KXZ43310.1 - 1.7 9.3 11.9 15 6.3 0.0 4.6 4 0 0 4 4 4 0 SlyX TACC_C PF05010.14 KXZ43310.1 - 2 8.2 7.4 0.31 10.8 0.7 2.7 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal V_ATPase_I PF01496.19 KXZ43310.1 - 2.3 6.0 3.3 2.2 6.1 0.1 2.3 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.25 KXZ43310.1 - 2.6 7.7 9.3 7.7 6.1 0.1 3.0 3 0 0 3 3 3 0 Syntaxin ZapB PF06005.12 KXZ43310.1 - 5.4 7.5 7.4 51 4.4 0.1 2.9 2 0 0 2 2 2 0 Cell division protein ZapB DUF1993 PF09351.10 KXZ43310.1 - 7.5 6.7 13.1 0.19 11.9 2.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) Cgr1 PF03879.14 KXZ43311.1 - 1.4e-05 25.4 22.8 1.4e-05 25.4 22.8 2.1 1 1 1 2 2 2 1 Cgr1 family DUF3987 PF13148.6 KXZ43311.1 - 2.3 7.1 18.0 0.37 9.7 9.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF4366 PF14283.6 KXZ43312.1 - 0.17 11.9 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Ribosomal_S7e PF01251.18 KXZ43313.1 - 1.2e-86 289.2 0.8 1.3e-86 289.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Herpes_BLRF2 PF05812.12 KXZ43313.1 - 0.013 15.6 1.5 0.087 13.0 0.8 2.4 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein Peptidase_C1 PF00112.23 KXZ43314.1 - 3.4e-34 118.9 5.3 4.6e-34 118.4 5.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CRAL_TRIO_2 PF13716.6 KXZ43314.1 - 2e-18 66.9 0.0 2.9e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KXZ43314.1 - 0.00018 21.3 0.3 0.004 16.9 0.2 2.6 2 1 0 2 2 2 1 CRAL/TRIO domain Peptidase_C1_2 PF03051.15 KXZ43314.1 - 0.66 8.7 1.4 1.6 7.5 0.9 1.7 2 0 0 2 2 2 0 Peptidase C1-like family Abhydro_lipase PF04083.16 KXZ43315.1 - 3.7e-16 58.4 0.0 6.2e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KXZ43315.1 - 2.4e-08 33.9 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ43315.1 - 0.12 11.6 0.9 8.9 5.5 0.0 2.9 3 1 0 3 3 3 0 Serine aminopeptidase, S33 Pkinase PF00069.25 KXZ43316.1 - 1.1e-58 198.7 0.0 1.5e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43316.1 - 3.3e-31 108.5 0.0 4.7e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ43316.1 - 8.5e-08 31.8 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ43316.1 - 6e-06 25.3 0.0 1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase GTP_EFTU PF00009.27 KXZ43317.1 - 1e-45 155.7 0.1 1.7e-45 155.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXZ43317.1 - 7.3e-13 48.7 1.2 2.5e-11 43.8 0.2 3.0 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXZ43317.1 - 7.7e-11 42.3 0.0 3.4e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXZ43317.1 - 7.7e-06 26.0 0.0 0.0028 17.7 0.0 3.1 3 1 1 4 4 4 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KXZ43317.1 - 0.0061 16.4 0.3 0.024 14.5 0.3 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Mg-por_mtran_C PF07109.11 KXZ43318.1 - 1.1e-36 125.0 0.1 3.2e-36 123.6 0.0 1.8 2 0 0 2 2 2 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_23 PF13489.6 KXZ43318.1 - 9.6e-12 45.0 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ43318.1 - 3.4e-10 40.5 0.2 1.4e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ43318.1 - 1.5e-06 28.8 0.0 3.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ43318.1 - 3.4e-05 24.4 0.1 0.00015 22.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ43318.1 - 0.00029 20.7 0.1 0.00072 19.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXZ43318.1 - 0.0083 16.1 0.0 0.02 14.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXZ43318.1 - 0.014 14.8 0.5 0.039 13.4 0.4 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXZ43318.1 - 0.051 12.9 0.0 0.12 11.6 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXZ43318.1 - 0.069 12.7 0.2 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXZ43318.1 - 0.078 12.3 0.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 KXZ43318.1 - 0.082 11.9 0.0 0.38 9.7 0.0 1.8 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 KXZ43318.1 - 0.15 12.0 0.1 1.3 9.0 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Trypsin_2 PF13365.6 KXZ43319.1 - 4.4e-33 115.3 3.5 7.6e-33 114.5 3.5 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KXZ43319.1 - 6.7e-14 52.0 0.1 1.3e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 KXZ43319.1 - 2.5e-10 40.5 0.2 5.7e-10 39.4 0.2 1.6 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KXZ43319.1 - 6.3e-07 29.1 1.0 0.0049 16.7 0.1 2.8 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KXZ43319.1 - 0.00038 20.7 0.1 0.54 10.6 0.0 2.6 2 0 0 2 2 2 2 PDZ domain ALS2CR11 PF15729.5 KXZ43319.1 - 6.2 5.9 5.0 10 5.1 0.1 2.1 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 candidate 11 RCC1 PF00415.18 KXZ43320.1 - 9.5e-60 199.0 10.7 6e-11 42.8 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ43320.1 - 1e-29 101.7 31.4 2.6e-07 30.3 0.1 7.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat TFIIA PF03153.13 KXZ43321.1 - 5.2 7.0 5.6 7.2 6.5 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DRY_EERY PF09750.9 KXZ43322.1 - 1.3e-21 77.2 0.1 5.1e-20 72.1 0.0 2.6 3 0 0 3 3 3 1 Alternative splicing regulator GRP PF07172.11 KXZ43322.1 - 6.6 7.5 26.4 1.6 9.5 5.1 2.9 2 0 0 2 2 2 0 Glycine rich protein family Ribosomal_S17e PF00833.18 KXZ43324.1 - 3.1e-61 204.7 1.2 3.5e-61 204.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 ANAPC4_WD40 PF12894.7 KXZ43325.1 - 0.0055 17.0 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KXZ43327.1 - 2e-07 30.8 0.4 4.7e-07 29.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ43327.1 - 0.0026 17.6 0.4 0.0069 16.2 0.4 1.7 1 1 0 1 1 1 1 F-box domain GBP_PSP PF02425.15 KXZ43329.1 - 0.086 12.5 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide Adaptin_N PF01602.20 KXZ43330.1 - 2.6e-05 23.0 0.2 4.4e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 KXZ43330.1 - 4.7 7.8 10.3 13 6.4 0.3 5.3 4 0 0 4 4 4 0 HEAT repeat Trehalose_PPase PF02358.16 KXZ43331.1 - 6.5e-51 172.7 0.0 7.6e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Epimerase PF01370.21 KXZ43332.1 - 2e-15 56.9 0.0 2.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXZ43332.1 - 5.9e-13 49.1 0.0 9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXZ43332.1 - 1.3e-09 37.5 0.0 1.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXZ43332.1 - 2.5e-07 30.5 0.1 3.9e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KXZ43332.1 - 4.2e-06 26.1 0.0 3e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Ldh_1_N PF00056.23 KXZ43332.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXZ43332.1 - 0.028 13.8 0.0 0.055 12.9 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXZ43332.1 - 0.17 11.3 0.1 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase EVE PF01878.18 KXZ43333.1 - 4.6e-52 175.9 0.0 6.5e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 EVE domain Epimerase PF01370.21 KXZ43334.1 - 5.8e-22 78.3 0.0 8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ43334.1 - 1.4e-13 50.5 0.0 1.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXZ43334.1 - 2.5e-11 43.5 0.0 4e-11 42.9 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXZ43334.1 - 1.3e-10 41.5 0.2 3.2e-10 40.2 0.0 1.8 3 0 0 3 3 3 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXZ43334.1 - 1.3e-09 37.6 0.4 2.7e-08 33.3 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KXZ43334.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family KR PF08659.10 KXZ43334.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 KR domain SDA1 PF05285.12 KXZ43335.1 - 0.05 13.0 18.1 0.061 12.8 18.1 1.1 1 0 0 1 1 1 0 SDA1 Cecropin PF00272.19 KXZ43335.1 - 0.12 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Cecropin family Nop14 PF04147.12 KXZ43335.1 - 0.58 8.3 21.1 0.67 8.1 21.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KXZ43335.1 - 1.6 8.0 20.1 1.9 7.8 20.1 1.1 1 0 0 1 1 1 0 BUD22 LRR_4 PF12799.7 KXZ43336.1 - 1.1e-07 32.0 1.2 0.1 13.0 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ43336.1 - 1.5e-06 27.8 0.5 0.0028 17.4 0.3 2.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 KXZ43336.1 - 0.12 13.0 1.1 84 4.3 0.2 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat FNIP PF05725.12 KXZ43336.1 - 0.17 12.1 0.9 0.35 11.1 0.9 1.5 1 0 0 1 1 1 0 FNIP Repeat F-box-like PF12937.7 KXZ43337.1 - 0.11 12.4 0.5 0.28 11.1 0.5 1.6 1 0 0 1 1 1 0 F-box-like RNA_pol_Rpc4 PF05132.14 KXZ43339.1 - 1.5e-25 90.4 0.0 5.5e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase III RPC4 DUF498 PF04430.14 KXZ43340.1 - 5.7e-25 87.5 0.0 7e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Fer4 PF00037.27 KXZ43341.1 - 1e-13 50.5 16.2 1e-07 31.5 4.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXZ43341.1 - 5e-13 49.4 10.5 5e-13 49.4 10.5 1.7 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXZ43341.1 - 7.2e-10 39.7 6.1 0.0003 21.6 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KXZ43341.1 - 3.9e-09 36.8 1.9 0.0002 21.7 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXZ43341.1 - 5.7e-09 36.0 20.6 1.4e-06 28.3 12.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KXZ43341.1 - 1.1e-08 35.0 32.5 1e-05 25.5 12.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXZ43341.1 - 2.3e-08 34.1 10.4 4.7e-08 33.1 10.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXZ43341.1 - 1e-06 28.5 17.6 0.0004 20.3 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KXZ43341.1 - 1.1e-06 28.3 12.5 0.0028 17.7 2.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KXZ43341.1 - 3.6e-06 27.1 10.7 0.0003 21.1 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXZ43341.1 - 0.00024 21.6 11.1 0.048 14.2 12.5 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KXZ43341.1 - 0.0093 16.5 14.2 0.55 10.8 2.3 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KXZ43341.1 - 0.015 15.4 8.1 6.5 7.0 7.5 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KXZ43341.1 - 0.024 14.8 5.7 0.58 10.4 0.2 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ETF_QO PF05187.13 KXZ43341.1 - 0.14 12.3 5.6 0.42 10.8 0.5 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 KXZ43341.1 - 0.14 13.1 16.3 0.35 11.9 4.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 KXZ43341.1 - 1.1 10.1 10.2 0.45 11.3 0.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 KXZ43341.1 - 1.7 9.6 14.1 2.6 9.0 1.8 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Rhodanese PF00581.20 KXZ43342.1 - 7e-06 26.5 0.0 2.5e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain BUD22 PF09073.10 KXZ43343.1 - 6.2 6.1 28.1 0.04 13.3 17.7 2.2 2 0 0 2 2 2 0 BUD22 BAT2_N PF07001.11 KXZ43344.1 - 0.93 9.9 12.5 1.1 9.7 12.5 1.0 1 0 0 1 1 1 0 BAT2 N-terminus RCC1_2 PF13540.6 KXZ43346.1 - 2.6e-32 109.9 24.4 3.7e-07 29.8 0.2 5.9 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXZ43346.1 - 2e-18 66.8 22.3 0.0012 19.4 0.4 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat HupH_C PF04809.13 KXZ43346.1 - 0.042 13.6 4.6 10 5.9 0.0 4.3 5 0 0 5 5 5 0 HupH hydrogenase expression protein, C-terminal conserved region FtsA PF14450.6 KXZ43346.1 - 0.043 14.2 5.5 1.5e+02 2.9 0.1 4.9 5 0 0 5 5 5 0 Cell division protein FtsA DOT1 PF08123.13 KXZ43346.1 - 0.18 11.3 2.8 80 2.7 0.0 4.3 5 0 0 5 5 5 0 Histone methylation protein DOT1 DUF2093 PF09866.9 KXZ43346.1 - 1 8.8 3.2 67 3.0 0.1 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2093) PEP_hydrolase PF09370.10 KXZ43346.1 - 1.2 8.3 4.4 15 4.7 0.2 3.0 1 1 2 3 3 3 0 Phosphoenolpyruvate hydrolase-like DUF4690 PF15756.5 KXZ43347.1 - 0.065 13.8 1.2 0.27 11.8 0.7 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Ank_2 PF12796.7 KXZ43348.1 - 2.7e-11 43.9 0.1 4.5e-10 40.0 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ43348.1 - 9.1e-09 35.4 0.1 1e-06 28.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ43348.1 - 1.9e-08 34.7 0.0 0.00028 21.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43348.1 - 1.8e-07 31.3 0.0 0.0032 17.8 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXZ43348.1 - 4.7e-05 23.5 0.0 0.083 13.5 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat AAA_25 PF13481.6 KXZ43348.1 - 0.018 14.6 0.2 0.048 13.2 0.2 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXZ43348.1 - 0.02 14.6 0.0 0.063 13.0 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KXZ43348.1 - 0.032 14.5 0.0 0.19 12.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ43348.1 - 0.73 10.2 7.2 0.59 10.5 0.4 3.7 3 1 0 3 3 3 0 AAA ATPase domain Cbl_N2 PF02761.14 KXZ43348.1 - 3.5 8.4 5.5 0.4 11.4 0.5 2.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain Ank_2 PF12796.7 KXZ43349.1 - 3.4e-56 187.8 1.0 1.3e-20 73.8 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43349.1 - 1.9e-33 114.4 0.1 5.6e-11 42.8 0.0 5.0 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43349.1 - 4.6e-33 112.2 0.0 8.8e-07 29.1 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXZ43349.1 - 2.8e-29 100.8 1.7 3.2e-08 33.7 0.1 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43349.1 - 3.1e-27 91.6 0.0 1.3e-05 25.2 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat DUF2474 PF10617.9 KXZ43349.1 - 0.092 12.6 3.7 0.25 11.2 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Ank_2 PF12796.7 KXZ43350.1 - 1.5e-23 83.2 0.1 3.6e-13 49.9 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43350.1 - 4.6e-20 71.1 0.0 6.9e-06 26.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXZ43350.1 - 9.8e-19 67.5 0.0 2.3e-08 34.4 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43350.1 - 7e-18 64.5 0.0 1.9e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43350.1 - 1.9e-16 58.5 0.0 1.6e-05 24.9 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KXZ43351.1 - 7.7e-53 177.0 8.5 8.6e-20 71.1 0.8 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ43351.1 - 1.7e-40 136.6 10.5 3.5e-10 39.9 0.0 6.5 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43351.1 - 1.4e-39 132.8 11.1 1.1e-07 32.0 0.4 7.6 6 1 1 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 KXZ43351.1 - 1.5e-37 127.5 0.1 1.7e-11 44.4 0.1 5.1 1 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43351.1 - 5.8e-35 115.4 2.2 9e-05 22.6 0.0 8.2 8 1 1 9 9 9 5 Ankyrin repeat VHS PF00790.19 KXZ43351.1 - 0.0047 16.8 0.1 4.9 7.0 0.0 3.4 3 0 0 3 3 3 1 VHS domain PUL PF08324.11 KXZ43351.1 - 0.0059 15.9 0.4 1.2 8.3 0.1 2.4 2 0 0 2 2 2 2 PUL domain Peptidase_M16 PF00675.20 KXZ43351.1 - 0.16 12.0 0.1 21 5.1 0.0 3.5 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) DUF2274 PF10038.9 KXZ43351.1 - 0.74 10.3 5.4 13 6.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2274) Ank_5 PF13857.6 KXZ43352.1 - 6.5e-24 83.7 8.1 4.9e-09 36.3 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ43352.1 - 1.2e-23 83.1 0.9 2.1e-13 50.4 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43352.1 - 1.6e-23 83.1 1.1 4.7e-18 65.6 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43352.1 - 4.8e-23 80.5 4.6 6.7e-08 32.6 0.1 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KXZ43352.1 - 4.3e-21 72.7 0.2 1.3e-06 28.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Big_10 PF17964.1 KXZ43352.1 - 0.012 15.6 0.3 0.83 9.6 0.1 2.1 1 1 1 2 2 2 0 Bacterial Ig domain DUF2384 PF09722.10 KXZ43352.1 - 0.023 14.7 0.7 8.6 6.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) GST_N_5 PF18485.1 KXZ43352.1 - 0.23 11.8 1.6 6.3 7.2 0.2 2.6 2 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain B_lectin PF01453.24 KXZ43353.1 - 3.1e-05 24.5 0.0 8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 D-mannose binding lectin PQQ PF01011.21 KXZ43353.1 - 0.0014 18.5 0.2 0.0072 16.2 0.2 2.3 1 1 1 2 2 2 1 PQQ enzyme repeat Ank_5 PF13857.6 KXZ43354.1 - 1.3e-28 98.7 0.3 2.7e-14 53.0 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43354.1 - 4.6e-27 94.4 1.1 4e-13 49.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43354.1 - 3.2e-20 71.6 0.2 4e-09 36.5 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXZ43354.1 - 3.9e-20 71.9 0.0 5.6e-07 30.0 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43354.1 - 6.7e-17 59.9 0.0 6.5e-05 23.0 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat DUF2384 PF09722.10 KXZ43354.1 - 0.018 15.1 0.0 0.47 10.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) VHS PF00790.19 KXZ43355.1 - 0.0013 18.6 0.1 0.036 13.9 0.0 2.3 2 0 0 2 2 2 2 VHS domain Ank PF00023.30 KXZ43356.1 - 4e-16 58.6 1.8 1.1e-06 28.8 0.2 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ43356.1 - 7.4e-15 54.8 0.1 2.7e-10 40.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43356.1 - 4.9e-14 51.1 0.2 0.00041 20.6 0.1 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KXZ43356.1 - 3.6e-13 49.9 0.1 6.1e-07 29.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43356.1 - 5.8e-13 49.1 0.1 1.3e-07 32.0 0.0 2.9 2 1 0 3 3 3 2 Ankyrin repeats (many copies) ABC_tran PF00005.27 KXZ43357.1 - 1.6e-19 70.8 0.0 2.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Ank_2 PF12796.7 KXZ43357.1 - 1.1e-08 35.5 0.0 2.8e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43357.1 - 2.3e-06 27.5 0.1 0.0012 19.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXZ43357.1 - 2.6e-05 24.5 0.7 0.00022 21.5 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXZ43357.1 - 3.1e-05 24.2 0.8 0.0044 17.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ43357.1 - 5.6e-05 23.6 0.0 0.00018 22.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXZ43357.1 - 0.0025 18.2 0.1 0.0079 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain PsiA PF06952.11 KXZ43357.1 - 0.028 13.7 0.1 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 PsiA protein RsgA_GTPase PF03193.16 KXZ43357.1 - 0.068 13.1 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KXZ43357.1 - 0.069 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KXZ43357.1 - 0.073 13.0 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 KXZ43357.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ43357.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 KXZ43357.1 - 0.26 10.7 11.6 0.51 9.7 11.6 1.5 1 1 0 1 1 1 0 ABC-2 type transporter Dickkopf_N PF04706.12 KXZ43358.1 - 7.4 7.1 18.6 0.17 12.4 9.3 2.8 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Chlam_PMP PF02415.17 KXZ43359.1 - 1.1e-14 53.8 52.4 0.024 15.1 1.3 9.0 8 0 0 8 8 8 7 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ub-Mut7C PF14451.6 KXZ43359.1 - 0.0002 21.2 2.9 2.7 7.9 0.0 5.2 2 2 5 7 7 7 2 Mut7-C ubiquitin VacA2 PF03077.14 KXZ43359.1 - 0.016 15.1 34.6 0.028 14.2 0.6 5.9 1 1 6 7 7 7 0 Putative vacuolating cytotoxin DotA PF11388.8 KXZ43359.1 - 0.18 12.0 1.8 10 6.4 0.1 2.5 2 0 0 2 2 2 0 Phagosome trafficking protein DotA Ocnus PF05005.15 KXZ43359.1 - 6.7 6.9 8.3 16 5.7 0.1 3.4 2 2 2 4 4 4 0 Janus/Ocnus family (Ocnus) Ank_2 PF12796.7 KXZ43361.1 - 0.0003 21.3 0.0 0.018 15.7 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43361.1 - 0.0004 20.7 0.0 0.03 14.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXZ43361.1 - 0.0065 16.9 0.0 0.063 13.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat DUF5423 PF17461.2 KXZ43361.1 - 0.025 13.5 0.7 0.049 12.5 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Ank_5 PF13857.6 KXZ43361.1 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) NDUF_B12 PF08122.12 KXZ43361.1 - 0.21 11.7 0.2 0.74 9.9 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family REJ PF02010.15 KXZ43363.1 - 5.6e-12 45.2 0.0 2.3e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 REJ domain EGF_2 PF07974.13 KXZ43363.1 - 0.00012 22.4 8.1 0.00012 22.4 8.1 7.5 5 2 1 6 6 6 3 EGF-like domain SKG6 PF08693.10 KXZ43363.1 - 0.048 13.1 4.1 0.15 11.5 4.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EF-hand_1 PF00036.32 KXZ43364.1 - 5.4e-05 22.5 0.0 0.00012 21.4 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43364.1 - 0.0012 18.6 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ43364.1 - 0.0023 18.3 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ43364.1 - 0.0027 17.1 0.1 0.0055 16.2 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ43364.1 - 0.008 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair Cuticle_1 PF08140.11 KXZ43364.1 - 0.073 13.1 1.3 38 4.4 0.1 3.4 3 0 0 3 3 3 0 Crustacean cuticle protein repeat Porin_6 PF16939.5 KXZ43364.1 - 0.083 12.0 0.2 12 4.8 0.0 2.3 2 0 0 2 2 2 0 Putative porin Tmemb_170 PF10190.9 KXZ43364.1 - 0.092 13.1 10.7 8.8 6.8 0.4 3.3 2 1 1 3 3 3 0 Putative transmembrane protein 170 RicinB_lectin_2 PF14200.6 KXZ43365.1 - 4.8e-47 158.6 24.2 1.1e-18 67.7 0.1 4.5 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ43365.1 - 1.9e-35 121.9 9.4 3.2e-17 63.0 4.3 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ43365.1 - 1.8e-30 106.3 8.3 1.8e-30 106.3 8.3 2.8 3 1 1 4 4 4 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ43365.1 - 2.2e-11 43.6 7.8 2.7e-05 23.8 1.0 2.5 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain Herpes_UL52 PF03121.15 KXZ43365.1 - 0.028 14.3 0.1 0.19 11.7 0.0 2.5 3 0 0 3 3 3 0 Herpesviridae UL52/UL70 DNA primase zf-Nse PF11789.8 KXZ43366.1 - 0.0088 15.8 1.2 0.015 15.1 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXZ43366.1 - 0.025 14.6 4.4 0.045 13.8 4.4 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KXZ43366.1 - 0.047 14.0 3.5 0.081 13.3 3.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KXZ43366.1 - 1.5 8.7 5.2 0.39 10.6 2.1 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RicinB_lectin_2 PF14200.6 KXZ43367.1 - 1.4e-42 144.3 18.9 9.4e-17 61.5 0.0 4.8 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ43367.1 - 4.3e-34 117.5 5.4 1.2e-16 61.1 3.3 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ43367.1 - 1.1e-31 110.3 6.8 6.8e-31 107.7 6.1 2.4 1 1 1 2 2 2 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ43367.1 - 1.1e-08 34.8 4.5 0.00018 21.1 0.6 2.6 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain EF-hand_1 PF00036.32 KXZ43367.1 - 8.5e-05 21.8 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43367.1 - 0.0033 17.2 0.0 0.0085 16.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ43367.1 - 0.0038 17.6 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ43367.1 - 0.018 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 EF hand Herpes_UL52 PF03121.15 KXZ43367.1 - 0.11 12.4 0.0 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase RNA_pol_Rpb8 PF03870.15 KXZ43370.1 - 9.2e-48 162.0 0.1 1e-47 161.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KXZ43370.1 - 2.7e-06 27.4 0.2 0.0001 22.3 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Clp_N PF02861.20 KXZ43371.1 - 0.0056 16.8 0.1 4.6 7.4 0.0 2.5 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component PaREP1 PF05942.11 KXZ43371.1 - 0.031 14.2 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family RanGAP1_C PF07834.11 KXZ43371.1 - 0.036 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 RanGAP1 C-terminal domain PP28 PF10252.9 KXZ43372.1 - 0.00063 20.1 3.4 0.00063 20.1 3.4 1.9 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 Pet100 PF09803.9 KXZ43372.1 - 0.34 11.5 1.1 0.86 10.2 1.1 1.7 1 0 0 1 1 1 0 Pet100 Cwf_Cwc_15 PF04889.12 KXZ43372.1 - 0.37 10.5 14.4 0.57 9.9 14.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP_N PF17093.5 KXZ43372.1 - 2.3 8.5 9.4 0.13 12.5 4.2 1.6 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Ebola_NP PF05505.12 KXZ43372.1 - 2.8 6.1 13.9 13 3.9 1.4 1.8 1 1 1 2 2 2 0 Ebola nucleoprotein Cys_Met_Meta_PP PF01053.20 KXZ43373.1 - 5.4e-134 446.5 0.0 6.1e-134 446.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXZ43373.1 - 2.8e-06 26.5 0.0 4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 KXZ43373.1 - 0.0021 17.1 0.0 0.075 12.0 0.0 2.2 2 0 0 2 2 2 2 L-seryl-tRNA selenium transferase Bac_rhodopsin PF01036.18 KXZ43374.1 - 9.8e-10 38.4 10.1 1.3e-09 37.9 10.1 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HATPase_c PF02518.26 KXZ43375.1 - 1.7e-15 57.5 0.5 1.7e-14 54.3 0.1 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXZ43375.1 - 0.0009 19.2 0.0 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KXZ43375.1 - 0.074 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Guanylate_cyc PF00211.20 KXZ43376.1 - 4.5e-35 120.9 0.0 8.1e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Response_reg PF00072.24 KXZ43376.1 - 1.3e-30 105.8 0.0 3.9e-30 104.3 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HAUS-augmin3 PF14932.6 KXZ43376.1 - 4.8 6.7 14.7 8.9 5.8 14.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Peptidase_C58 PF03543.14 KXZ43376.1 - 6.6 6.4 7.5 13 5.5 0.0 2.5 2 1 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen PGM_PMM_I PF02878.16 KXZ43378.1 - 1.6e-12 47.3 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DsbD_2 PF13386.6 KXZ43378.1 - 0.072 13.0 2.6 0.13 12.1 2.6 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region CAF-1_p60_C PF15512.6 KXZ43379.1 - 0.032 14.7 0.3 0.05 14.1 0.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Semialdhyde_dh PF01118.24 KXZ43380.1 - 2e-23 83.1 0.0 3.1e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KXZ43380.1 - 6.3e-14 52.5 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain NmrA PF05368.13 KXZ43380.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Ank_2 PF12796.7 KXZ43381.1 - 0.00076 20.0 0.0 0.6 10.7 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43381.1 - 0.041 14.5 0.0 1.7e+02 2.9 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Rhomboid PF01694.22 KXZ43383.1 - 1.9e-09 37.7 0.4 1e-05 25.6 0.0 2.4 1 1 1 2 2 2 2 Rhomboid family Myb_DNA-binding PF00249.31 KXZ43384.1 - 4.1e-18 65.3 0.0 8.6e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ43384.1 - 1.4e-13 50.9 0.0 9.3e-09 35.4 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Cwf_Cwc_15 PF04889.12 KXZ43384.1 - 0.18 11.5 1.8 0.31 10.7 1.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Trns_repr_metal PF02583.17 KXZ43385.1 - 0.004 17.5 1.4 0.004 17.5 1.4 2.1 2 0 0 2 2 2 1 Metal-sensitive transcriptional repressor ATG16 PF08614.11 KXZ43385.1 - 0.23 11.7 6.8 0.35 11.0 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1631 PF07793.11 KXZ43385.1 - 9.8 4.5 15.2 16 3.8 15.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) EF-hand_7 PF13499.6 KXZ43387.1 - 0.019 15.4 0.0 0.056 13.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KXZ43387.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ43387.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain TetR_C_20 PF17925.1 KXZ43387.1 - 0.68 10.3 5.1 6.1 7.2 3.6 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Diphthami_syn_2 PF01902.17 KXZ43388.1 - 9.2e-09 35.1 0.0 0.012 15.2 0.0 3.1 3 0 0 3 3 3 3 Diphthamide synthase Chloroa_b-bind PF00504.21 KXZ43390.1 - 0.00047 20.7 0.0 0.00074 20.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein 2OG-FeII_Oxy_2 PF13532.6 KXZ43391.1 - 2.4e-11 44.2 0.0 3.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RAP PF08373.10 KXZ43392.1 - 0.00013 21.9 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 RAP domain YtxH PF12732.7 KXZ43392.1 - 0.0024 18.3 0.0 0.0024 18.3 0.0 2.1 2 0 0 2 2 2 1 YtxH-like protein DUF3431 PF11913.8 KXZ43393.1 - 2.3e-06 27.5 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3638 PF12340.8 KXZ43397.1 - 2.5e-14 53.2 0.0 4.3e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) NOA36 PF06524.12 KXZ43398.1 - 0.53 9.6 3.8 0.75 9.1 3.8 1.1 1 0 0 1 1 1 0 NOA36 protein Aha1_N PF09229.11 KXZ43399.1 - 2.1e-10 40.9 0.0 3.4e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 Activator of Hsp90 ATPase, N-terminal bPH_2 PF03703.14 KXZ43400.1 - 5.3e-10 39.4 0.2 6.9e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Bacterial PH domain RPGR1_C PF18111.1 KXZ43400.1 - 0.0015 18.4 0.1 0.59 10.0 0.0 2.9 3 0 0 3 3 3 2 Retinitis pigmentosa G-protein regulator interacting C-terminal AP3B1_C PF14796.6 KXZ43400.1 - 0.097 12.9 0.0 21 5.3 0.0 2.2 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Ribosomal_60s PF00428.19 KXZ43400.1 - 0.18 12.4 5.2 0.43 11.2 5.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein SpoVAC_SpoVAEB PF03862.13 KXZ43406.1 - 0.062 13.6 1.7 0.093 13.0 1.7 1.2 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein SPT_ssu-like PF11779.8 KXZ43406.1 - 0.099 12.3 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Mit_KHE1 PF10173.9 KXZ43407.1 - 4.1e-15 56.4 3.3 8.8e-07 29.2 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial K+-H+ exchange-related Ribosomal_S14 PF00253.21 KXZ43408.1 - 1.6e-18 66.2 1.2 1.8e-18 66.0 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1451 PF07295.11 KXZ43408.1 - 0.13 12.3 0.4 0.14 12.2 0.4 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Prim_Zn_Ribbon PF08273.12 KXZ43408.1 - 0.32 11.3 4.3 6.6 7.1 0.6 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Hist_deacetyl PF00850.19 KXZ43409.1 - 2.2e-28 99.6 0.0 2.8e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.20 KXZ43410.1 - 4.2e-24 84.9 0.0 3e-19 69.2 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXZ43410.1 - 0.047 13.2 0.1 0.07 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CD99L2 PF12301.8 KXZ43410.1 - 0.072 13.4 6.7 0.12 12.7 6.7 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Glyco_transf_5 PF08323.11 KXZ43411.1 - 1.2e-28 100.5 0.0 8.4e-16 58.4 0.1 3.3 3 0 0 3 3 3 3 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXZ43411.1 - 0.0003 20.4 0.0 0.8 9.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ43411.1 - 0.0073 16.3 0.1 7 6.6 0.1 3.9 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Enkurin PF13864.6 KXZ43412.1 - 7.1e-25 87.3 1.7 9.6e-25 86.9 1.7 1.2 1 0 0 1 1 1 1 Calmodulin-binding DUF3053 PF11254.8 KXZ43412.1 - 0.0089 15.6 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) Peptidase_M43 PF05572.13 KXZ43413.1 - 0.00049 20.0 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 Pregnancy-associated plasma protein-A Peptidase_M43 PF05572.13 KXZ43414.1 - 5.7e-24 84.8 1.0 8.3e-08 32.3 0.1 4.0 3 0 0 3 3 3 3 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXZ43414.1 - 6.4e-11 42.8 0.0 0.068 13.3 0.0 3.6 3 0 0 3 3 3 3 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KXZ43414.1 - 8e-06 25.8 0.1 1.6 8.6 0.0 3.3 3 0 0 3 3 3 3 Matrixin Rnk_N PF14760.6 KXZ43414.1 - 0.33 11.5 5.6 7.8 7.1 0.6 3.1 2 0 0 2 2 2 0 Rnk N-terminus MarR_2 PF12802.7 KXZ43414.1 - 0.44 10.5 2.2 25 4.9 0.0 3.4 3 0 0 3 3 3 0 MarR family Zincin_1 PF06262.11 KXZ43414.1 - 7.8 6.7 9.0 16 5.6 0.2 3.4 3 0 0 3 3 3 0 Zincin-like metallopeptidase mTERF PF02536.14 KXZ43415.1 - 0.0016 17.5 0.0 0.0031 16.5 0.0 1.3 1 1 0 1 1 1 1 mTERF LRR_6 PF13516.6 KXZ43416.1 - 0.0016 18.3 0.0 6.8 7.0 0.0 5.0 6 0 0 6 6 6 1 Leucine Rich repeat SSP160 PF06933.11 KXZ43416.1 - 0.026 12.7 3.9 0.031 12.5 3.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3720 PF12517.8 KXZ43416.1 - 0.77 10.7 3.6 1.6 9.7 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) DUF4202 PF13875.6 KXZ43417.1 - 1.8e-20 73.6 0.0 3.1e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) HemX PF04375.14 KXZ43417.1 - 0.02 14.2 5.3 0.03 13.6 5.3 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Herpes_gE PF02480.16 KXZ43417.1 - 0.035 12.9 0.7 0.049 12.4 0.7 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CO_deh_flav_C PF03450.17 KXZ43417.1 - 0.045 13.9 4.0 0.12 12.6 4.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain PrgH PF09480.10 KXZ43417.1 - 0.17 11.2 0.2 0.24 10.7 0.2 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Ni_hydr_CYTB PF01292.20 KXZ43417.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Ank_2 PF12796.7 KXZ43418.1 - 3.6e-10 40.3 1.1 0.00012 22.6 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43418.1 - 6.1e-09 36.2 6.3 0.034 14.7 0.0 5.4 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43418.1 - 2.3e-05 24.4 2.9 37 5.3 0.0 6.6 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 KXZ43418.1 - 0.34 11.4 2.6 28 5.4 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 KXZ43419.1 - 1.8e-12 47.7 4.4 5.1e-05 23.8 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43419.1 - 1.4e-09 38.3 13.1 0.63 10.7 0.1 7.7 4 3 5 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43419.1 - 5.8e-07 29.3 3.3 32 5.5 0.0 7.8 8 0 0 8 8 8 1 Ankyrin repeat SAT PF16073.5 KXZ43419.1 - 9.9 5.8 10.5 19 4.8 2.6 2.5 1 1 1 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis zf-MYND PF01753.18 KXZ43420.1 - 6.3e-07 29.4 3.9 1.2e-06 28.5 3.9 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ43420.1 - 0.088 13.1 2.8 0.17 12.2 2.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RRM_1 PF00076.22 KXZ43421.1 - 2.3e-18 65.7 0.0 3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ43421.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif TPR_12 PF13424.6 KXZ43422.1 - 1.5e-51 172.6 62.9 8.1e-16 58.1 8.8 7.7 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ43422.1 - 8.6e-35 117.7 54.5 2.3e-11 43.2 0.7 9.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ43422.1 - 2e-05 24.3 29.8 0.0082 16.1 0.4 7.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ43422.1 - 8.6e-05 23.1 2.7 8.6e-05 23.1 2.7 12.3 10 1 5 15 15 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ43422.1 - 0.00015 22.2 53.8 0.0024 18.3 1.9 8.5 4 1 5 9 9 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ43422.1 - 0.0015 18.3 0.3 0.0015 18.3 0.3 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ43422.1 - 0.0092 16.0 1.2 0.0092 16.0 1.2 9.0 10 0 0 10 10 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ43422.1 - 0.011 16.0 9.1 0.75 10.1 3.3 4.8 2 2 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.6 KXZ43422.1 - 0.13 12.5 0.0 0.73 10.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF4404 PF14357.6 KXZ43422.1 - 0.18 12.4 0.4 1.6 9.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Coatomer_E PF04733.14 KXZ43422.1 - 0.84 9.0 2.7 6.6 6.1 0.1 3.2 2 1 0 3 3 3 0 Coatomer epsilon subunit TPR_8 PF13181.6 KXZ43422.1 - 6.9 7.2 13.5 1.9 8.9 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF16 PF01519.16 KXZ43423.1 - 0.0023 18.4 6.7 0.0037 17.7 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 GrpE PF01025.19 KXZ43423.1 - 0.0037 16.9 2.6 0.0054 16.4 2.6 1.3 1 0 0 1 1 1 1 GrpE Gp58 PF07902.11 KXZ43423.1 - 0.0042 15.4 0.3 0.0053 15.1 0.3 1.1 1 0 0 1 1 1 1 gp58-like protein kleA_kleC PF17383.2 KXZ43423.1 - 0.008 16.5 1.9 0.015 15.6 1.9 1.4 1 0 0 1 1 1 1 Uncharacterized KorC regulated protein A Prominin PF05478.11 KXZ43423.1 - 0.015 13.2 2.3 0.019 13.0 2.3 1.1 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 KXZ43423.1 - 0.024 14.2 3.3 0.027 14.1 3.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2721 PF11026.8 KXZ43423.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) EMP24_GP25L PF01105.24 KXZ43423.1 - 0.025 14.5 1.6 0.035 14.0 1.6 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SlyX PF04102.12 KXZ43423.1 - 0.034 14.7 8.9 0.27 11.9 8.1 2.5 2 1 0 2 2 2 0 SlyX Phage_GP20 PF06810.11 KXZ43423.1 - 0.048 13.5 7.5 0.1 12.4 7.5 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4407 PF14362.6 KXZ43423.1 - 0.054 12.9 2.8 0.065 12.6 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXZ43423.1 - 0.065 12.3 5.0 0.081 12.0 5.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran_CTD PF16326.5 KXZ43423.1 - 0.13 12.5 7.0 0.24 11.6 7.0 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain XhlA PF10779.9 KXZ43423.1 - 0.16 12.2 4.9 0.35 11.1 4.9 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Ribosomal_L6e PF01159.19 KXZ43423.1 - 0.17 12.4 4.8 0.26 11.8 4.8 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e Mating_C PF12737.7 KXZ43423.1 - 0.25 10.5 3.0 0.49 9.6 3.0 1.4 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 CagA PF03507.13 KXZ43423.1 - 0.28 11.1 3.6 0.17 11.8 0.9 1.9 2 0 0 2 2 2 0 CagA exotoxin Csm1_N PF18504.1 KXZ43423.1 - 0.34 11.3 10.0 0.26 11.6 7.7 2.0 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF948 PF06103.11 KXZ43423.1 - 0.36 11.1 6.3 0.18 12.0 2.1 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 KXZ43423.1 - 0.36 9.7 0.3 0.34 9.8 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 KXZ43423.1 - 0.37 10.0 3.9 0.49 9.6 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DASH_Spc34 PF08657.10 KXZ43423.1 - 0.41 10.4 7.7 2.2 8.0 9.1 1.6 1 1 1 2 2 2 0 DASH complex subunit Spc34 TolA_bind_tri PF16331.5 KXZ43423.1 - 0.48 10.5 11.7 1 9.5 11.7 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation M_domain PF12938.7 KXZ43423.1 - 0.53 10.0 7.6 0.66 9.7 7.6 1.2 1 0 0 1 1 1 0 M domain of GW182 Fzo_mitofusin PF04799.13 KXZ43423.1 - 1.2 8.7 6.7 1.8 8.1 6.7 1.2 1 0 0 1 1 1 0 fzo-like conserved region FlaC_arch PF05377.11 KXZ43423.1 - 1.3 9.4 5.6 0.61 10.5 2.3 2.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KXZ43423.1 - 2.2 8.1 10.9 7.9 6.3 10.9 1.9 1 1 0 1 1 1 0 Septum formation initiator Nup54 PF13874.6 KXZ43423.1 - 2.8 8.0 13.5 10 6.2 10.0 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.12 KXZ43423.1 - 4.5 7.8 8.9 3.3 8.2 5.2 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4549 PF15082.6 KXZ43424.1 - 0.023 14.5 0.5 0.033 14.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) WD40 PF00400.32 KXZ43425.1 - 2.2e-22 78.9 8.8 0.00019 22.2 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ43425.1 - 2.1e-11 44.0 0.1 0.53 10.6 0.1 5.2 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ43425.1 - 0.025 14.5 0.0 3 7.7 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cpn10 PF00166.21 KXZ43428.1 - 6.6e-50 167.1 6.0 1.7e-26 92.1 0.2 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit S1 PF00575.23 KXZ43429.1 - 0.00046 20.5 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain PepX_C PF08530.10 KXZ43429.1 - 0.0039 17.2 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Atrophin-1 PF03154.15 KXZ43429.1 - 0.24 9.6 11.8 0.42 8.8 11.8 1.4 1 0 0 1 1 1 0 Atrophin-1 family GHMP_kinases_C PF08544.13 KXZ43429.1 - 0.94 9.9 4.8 0.97 9.8 0.1 2.8 3 0 0 3 3 3 0 GHMP kinases C terminal Dpy-30 PF05186.13 KXZ43431.1 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 KXZ43431.1 - 0.07 13.2 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Adenylate kinase eIF-3c_N PF05470.12 KXZ43432.1 - 3.7e-182 606.8 0.6 3.7e-182 606.8 0.6 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KXZ43432.1 - 5e-14 52.7 0.0 1.6e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 PCI domain DUF4363 PF14276.6 KXZ43432.1 - 0.069 13.3 2.2 0.41 10.8 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) SPX PF03105.19 KXZ43432.1 - 0.13 12.2 18.9 0.1 12.5 17.1 1.7 2 0 0 2 2 2 0 SPX domain SEEEED PF14797.6 KXZ43432.1 - 8.5 6.6 51.5 0.1 12.7 37.1 2.7 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex TOC159_MAD PF11886.8 KXZ43433.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain Sec7 PF01369.20 KXZ43436.1 - 2.6e-19 69.6 0.0 4.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXZ43436.1 - 7.1e-16 58.5 1.4 1.3e-15 57.7 0.6 1.8 1 1 1 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Adaptin_N PF01602.20 KXZ43437.1 - 0.0016 17.1 0.0 0.0026 16.4 0.0 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Sec1 PF00995.23 KXZ43440.1 - 5.1e-94 316.6 0.0 6.3e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CHCH PF06747.13 KXZ43441.1 - 2.8e-05 24.1 4.0 0.00013 22.0 0.7 2.4 2 1 0 2 2 2 1 CHCH domain CX9C PF16860.5 KXZ43441.1 - 0.0039 17.2 1.7 0.55 10.3 0.2 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, AAA_30 PF13604.6 KXZ43443.1 - 1.7e-14 54.0 0.3 3.6e-14 52.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 KXZ43443.1 - 2.3e-06 27.0 0.2 4.6e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KXZ43443.1 - 3.7e-06 27.3 1.2 4.5e-06 27.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain rve PF00665.26 KXZ43443.1 - 0.0014 18.8 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain AAA_22 PF13401.6 KXZ43443.1 - 0.018 15.3 0.1 1.2 9.4 0.1 2.5 1 1 0 1 1 1 0 AAA domain Spore_YtrH PF14034.6 KXZ43444.1 - 0.091 12.9 0.0 4.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein YtrH WLM PF08325.10 KXZ43445.1 - 3e-25 89.4 0.1 4.9e-24 85.5 0.0 1.9 1 1 1 2 2 2 2 WLM domain DUF45 PF01863.17 KXZ43445.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 SYS1 PF09801.9 KXZ43448.1 - 8.1e-10 39.0 7.4 1.1e-09 38.6 7.4 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Abhydrolase_8 PF06259.12 KXZ43449.1 - 1.2e-05 25.1 0.3 1.2e-05 25.1 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KXZ43449.1 - 0.027 13.7 0.8 7 5.8 0.0 3.0 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ43449.1 - 0.045 13.4 0.3 0.14 11.8 0.3 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold 4HBT PF03061.22 KXZ43450.1 - 1.5e-11 44.5 0.2 2.2e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KXZ43450.1 - 4.9e-11 43.2 0.0 5.9e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KXZ43450.1 - 0.06 12.6 0.6 2.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Acyl-ACP thioesterase AbfS_sensor PF18225.1 KXZ43450.1 - 0.073 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain Pkinase PF00069.25 KXZ43451.1 - 2.2e-60 204.3 0.0 2.7e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43451.1 - 1e-40 139.7 0.0 1.3e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NTF2 PF02136.20 KXZ43451.1 - 6.5e-08 33.2 0.0 1.9e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Kinase-like PF14531.6 KXZ43451.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ43451.1 - 0.002 17.5 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ43451.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXZ43451.1 - 0.018 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-RING_2 PF13639.6 KXZ43452.1 - 1.1e-10 41.6 6.1 1.8e-10 40.9 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXZ43452.1 - 1e-09 38.5 10.1 3.4e-09 36.9 10.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXZ43452.1 - 2.2e-07 30.6 5.8 4.3e-07 29.7 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ43452.1 - 8.4e-07 28.8 6.3 1.5e-06 27.9 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ43452.1 - 8.6e-06 25.7 1.9 1.6e-05 24.9 1.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXZ43452.1 - 0.00017 21.4 7.5 0.00027 20.7 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXZ43452.1 - 0.0003 20.8 5.0 0.00068 19.6 5.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXZ43452.1 - 0.00037 20.4 5.6 0.00068 19.5 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXZ43452.1 - 0.00044 19.9 4.9 0.00088 19.0 4.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KXZ43452.1 - 0.018 14.7 6.8 0.035 13.7 6.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXZ43452.1 - 0.021 14.7 4.9 0.038 13.9 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KXZ43452.1 - 0.24 11.6 2.7 0.56 10.4 2.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KXZ43452.1 - 0.54 10.6 6.8 1 9.7 6.8 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 KXZ43452.1 - 1 9.6 4.8 1.9 8.7 4.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 KXZ43452.1 - 1.2 9.3 6.2 2.5 8.3 6.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 KXZ43452.1 - 1.5 8.7 5.0 2 8.3 4.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KXZ43452.1 - 3.8 7.7 7.8 8.8 6.5 7.8 1.6 1 0 0 1 1 1 0 RING-variant domain WD40 PF00400.32 KXZ43455.1 - 2.8e-19 69.1 3.3 0.00015 22.4 0.2 7.8 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ43455.1 - 4.5e-07 30.1 0.6 2.7 8.4 0.0 6.9 6 3 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Laminin_II PF06009.12 KXZ43455.1 - 0.00047 20.2 5.3 0.00047 20.2 5.3 5.2 4 2 3 7 7 7 1 Laminin Domain II HELP PF03451.14 KXZ43455.1 - 0.0016 18.2 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 HELP motif TRAF_BIRC3_bd PF16673.5 KXZ43455.1 - 0.0038 17.0 1.4 0.0038 17.0 1.4 5.4 6 0 0 6 6 6 1 TNF receptor-associated factor BIRC3 binding domain ATG16 PF08614.11 KXZ43455.1 - 0.0073 16.5 20.2 0.0073 16.5 20.2 5.4 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) APOC4 PF15119.6 KXZ43455.1 - 0.049 13.9 0.2 0.4 11.0 0.1 2.6 2 1 1 3 3 3 0 Apolipoprotein C4 Globin PF00042.22 KXZ43455.1 - 0.22 12.1 1.7 0.68 10.5 0.1 2.4 2 0 0 2 2 2 0 Globin DUF4407 PF14362.6 KXZ43455.1 - 8.2 5.7 58.5 1.8 7.9 19.3 5.1 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) Mito_carr PF00153.27 KXZ43456.1 - 2.9e-20 72.0 0.1 5.5e-19 67.9 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Form_Nir_trans PF01226.17 KXZ43457.1 - 7.6e-65 218.5 22.5 9.3e-65 218.3 22.5 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter ORC2 PF04084.14 KXZ43459.1 - 1.5e-67 227.9 0.0 1.8e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MinE PF03776.14 KXZ43460.1 - 4.8e-06 26.5 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE DUF2475 PF10629.9 KXZ43461.1 - 0.59 10.4 9.4 12 6.2 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2475) RRM_1 PF00076.22 KXZ43462.1 - 6.2e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) dsrm PF00035.26 KXZ43462.1 - 0.0011 19.6 0.1 0.0029 18.3 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif RRM_7 PF16367.5 KXZ43462.1 - 0.027 14.6 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif His_Phos_1 PF00300.22 KXZ43463.1 - 1.5e-12 47.6 5.9 3.8e-10 39.8 0.3 3.3 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Rhodanese PF00581.20 KXZ43464.1 - 6.1e-06 26.7 0.0 2.4e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain BcsB PF03170.13 KXZ43464.1 - 0.1 10.9 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit MarR_2 PF12802.7 KXZ43464.1 - 0.25 11.3 2.2 0.93 9.4 0.5 2.4 2 0 0 2 2 2 0 MarR family Ribosomal_S30 PF04758.14 KXZ43465.1 - 1.2e-30 105.4 10.1 1.4e-30 105.3 10.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 adh_short_C2 PF13561.6 KXZ43467.1 - 1.9e-56 191.2 8.5 3.5e-54 183.8 8.5 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ43467.1 - 2.9e-49 167.2 2.5 4.1e-49 166.7 2.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ43467.1 - 3.4e-14 53.2 6.1 2.6e-13 50.3 6.1 2.0 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 KXZ43467.1 - 0.031 14.5 0.6 0.056 13.7 0.6 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_25 PF13649.6 KXZ43467.1 - 0.031 15.0 0.8 0.052 14.3 0.2 1.8 2 0 0 2 2 2 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 KXZ43467.1 - 0.092 12.8 1.6 0.16 12.0 1.6 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 KXZ43467.1 - 0.13 12.3 0.2 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXZ43467.1 - 0.18 11.7 1.5 0.33 10.8 1.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 KXZ43467.1 - 0.23 10.8 0.0 0.45 9.8 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) COX17 PF05051.13 KXZ43468.1 - 0.093 13.1 3.0 0.18 12.2 3.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 KXZ43468.1 - 0.37 11.0 8.5 0.58 10.4 8.5 1.3 1 0 0 1 1 1 0 CHCH domain PsbP PF01789.16 KXZ43470.1 - 4.2e-10 40.0 0.0 9.4e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 PsbP PAS_9 PF13426.7 KXZ43471.1 - 2.3e-43 146.7 0.0 2.2e-23 82.5 0.0 2.4 2 0 0 2 2 2 2 PAS domain Pkinase PF00069.25 KXZ43471.1 - 6.4e-40 137.2 0.0 7.3e-39 133.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43471.1 - 9.1e-20 71.0 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_3 PF08447.12 KXZ43471.1 - 2.8e-15 56.4 0.0 1.2e-07 31.9 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KXZ43471.1 - 6.3e-12 45.5 0.0 4.8e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KXZ43471.1 - 2.7e-10 40.4 0.0 1.9e-05 24.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KXZ43471.1 - 0.017 15.2 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 PAS domain Kinase-like PF14531.6 KXZ43471.1 - 0.048 13.0 0.1 0.075 12.3 0.1 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KXZ43472.1 - 7.9e-15 54.9 0.0 9.8e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43472.1 - 6.7e-05 22.3 0.0 8.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KXZ43473.1 - 2.8e-81 267.7 3.5 3.2e-22 78.4 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase PF00069.25 KXZ43473.1 - 6.7e-62 209.2 0.0 1.1e-61 208.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43473.1 - 1.2e-33 116.5 0.0 1.9e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ43473.1 - 8e-05 22.1 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MMR_HSR1 PF01926.23 KXZ43474.1 - 0.0022 18.1 0.1 0.0082 16.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXZ43474.1 - 0.0022 18.1 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 KXZ43474.1 - 0.018 15.5 0.0 0.05 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KXZ43474.1 - 0.051 13.5 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXZ43474.1 - 0.15 12.5 4.8 0.23 11.8 0.5 2.9 2 1 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 KXZ43474.1 - 0.15 11.6 0.2 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-MYND PF01753.18 KXZ43475.1 - 5.5e-07 29.6 13.1 1.2e-06 28.4 13.1 1.7 1 0 0 1 1 1 1 MYND finger Yip1 PF04893.17 KXZ43475.1 - 0.19 11.5 7.3 0.091 12.5 1.7 2.5 2 0 0 2 2 2 0 Yip1 domain SGBP_B_XBD PF18329.1 KXZ43477.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain RIO1 PF01163.22 KXZ43480.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SHIPPO-rpt PF07004.12 KXZ43482.1 - 5.4e-05 23.9 0.2 0.18 12.8 0.0 4.6 4 0 0 4 4 4 1 Sperm-tail PG-rich repeat ARID PF01388.21 KXZ43483.1 - 0.0037 17.9 0.0 0.0078 16.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Nop14 PF04147.12 KXZ43483.1 - 1.2 7.2 8.6 1.7 6.8 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family NAD_binding_10 PF13460.6 KXZ43484.1 - 5.6e-19 68.7 0.4 1.1e-18 67.8 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXZ43484.1 - 1.9e-12 47.2 0.0 3.3e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ43484.1 - 1.3e-08 34.2 0.0 4.3e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXZ43484.1 - 1.9e-07 30.9 0.0 2.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXZ43484.1 - 0.022 14.2 0.2 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXZ43484.1 - 0.082 12.0 0.1 0.36 9.9 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain NAC PF01849.18 KXZ43485.1 - 5.1e-24 84.0 2.4 4.7e-23 80.9 0.1 2.3 2 0 0 2 2 2 2 NAC domain DEAD PF00270.29 KXZ43486.1 - 4.4e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase DEAD PF00270.29 KXZ43487.1 - 1.6e-07 31.3 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase UVR PF02151.19 KXZ43487.1 - 0.0011 18.6 0.2 0.002 17.8 0.2 1.4 1 0 0 1 1 1 1 UvrB/uvrC motif Pkinase PF00069.25 KXZ43489.1 - 7.3e-31 107.5 0.0 1.4e-22 80.3 0.0 3.3 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43489.1 - 8e-30 104.0 0.0 5.3e-24 84.9 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43489.1 - 0.0003 19.7 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ43489.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ43489.1 - 0.047 13.6 1.6 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ43491.1 - 5.5e-30 104.6 0.0 4.8e-23 81.9 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43491.1 - 6.6e-29 101.0 0.0 4.1e-23 82.0 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43491.1 - 0.00018 20.5 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ43491.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ43491.1 - 0.045 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ43492.1 - 1.2e-28 100.1 0.0 2.1e-23 82.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ43492.1 - 1.5e-28 99.9 0.0 4.7e-22 78.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ43492.1 - 0.00043 19.2 0.0 0.00067 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ43492.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ43493.1 - 1.3e-29 103.4 0.0 4.7e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43493.1 - 6.5e-29 101.0 0.0 1.2e-23 83.7 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43493.1 - 0.00043 19.2 0.0 0.00063 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ43493.1 - 0.28 10.5 0.0 0.45 9.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ43494.1 - 6.9e-25 87.8 0.0 4.7e-24 85.1 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ43494.1 - 9.6e-25 87.4 0.0 1.1e-23 83.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ43494.1 - 0.00098 18.0 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ43494.1 - 0.23 10.8 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ubie_methyltran PF01209.18 KXZ43497.1 - 3.9e-54 183.5 0.0 4.8e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXZ43497.1 - 2.7e-22 79.3 0.0 4.7e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ43497.1 - 2.1e-20 73.1 0.0 3.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ43497.1 - 1.7e-16 60.4 0.0 1.9e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ43497.1 - 3.5e-13 50.1 0.0 5.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ43497.1 - 1.2e-12 48.0 0.0 1.9e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXZ43497.1 - 2e-08 34.3 0.0 2.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KXZ43497.1 - 0.00078 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXZ43497.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase GCD14 PF08704.10 KXZ43497.1 - 0.0035 17.0 0.0 0.0048 16.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 KXZ43497.1 - 0.0053 16.3 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXZ43497.1 - 0.024 14.8 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 KXZ43497.1 - 0.049 13.2 0.0 0.26 10.8 0.0 1.9 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 KXZ43497.1 - 0.073 11.6 0.0 0.088 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PP2C PF00481.21 KXZ43498.1 - 2.2e-31 109.4 0.0 4e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXZ43498.1 - 3.8e-06 26.9 0.1 3.7e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXZ43498.1 - 0.00072 19.3 0.5 0.0032 17.1 0.1 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C Disulph_isomer PF06491.11 KXZ43498.1 - 0.0036 17.4 0.0 0.0036 17.4 0.0 3.0 3 1 1 4 4 4 1 Disulphide isomerase UPF0016 PF01169.19 KXZ43499.1 - 1.1e-38 131.4 29.0 7.5e-21 74.3 8.7 3.0 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 TerC PF03741.16 KXZ43499.1 - 0.0015 18.3 3.9 0.0088 15.7 3.9 2.0 1 1 0 1 1 1 1 Integral membrane protein TerC family OFeT_1 PF16955.5 KXZ43499.1 - 0.017 14.8 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter 2OG-FeII_Oxy_3 PF13640.6 KXZ43500.1 - 1e-17 64.8 0.0 1.8e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ43500.1 - 0.00012 22.5 0.0 0.00026 21.4 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 KXZ43500.1 - 0.0012 19.4 11.7 0.002 18.6 9.2 2.6 2 1 0 2 2 2 1 ShK domain-like 2OG-FeII_Oxy_3 PF13640.6 KXZ43501.1 - 9.9e-17 61.6 0.0 2.1e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ43501.1 - 9.5e-05 22.8 0.0 0.00021 21.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 KXZ43501.1 - 0.00026 21.5 11.8 0.00071 20.1 9.7 2.7 2 1 0 2 2 2 1 ShK domain-like Acetyltransf_1 PF00583.25 KXZ43502.1 - 1.4e-11 44.7 0.0 2.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ43502.1 - 2e-08 34.2 0.0 5.7e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ43502.1 - 8.8e-07 29.3 0.0 2.5e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ43502.1 - 3.9e-06 26.7 0.0 8.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KXZ43502.1 - 0.0036 17.5 0.0 0.0055 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXZ43502.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNA_polI_A34 PF08208.11 KXZ43503.1 - 0.003 17.7 41.1 0.019 15.0 3.0 2.8 2 1 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 VIR_N PF15912.5 KXZ43503.1 - 0.25 10.9 3.9 0.32 10.6 3.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal SRP-alpha_N PF04086.13 KXZ43503.1 - 0.55 10.1 25.4 0.96 9.3 25.4 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mito_fiss_reg PF05308.11 KXZ43503.1 - 2.4 8.2 9.7 4.3 7.3 9.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator V_ATPase_I PF01496.19 KXZ43503.1 - 2.9 5.7 5.8 3.4 5.4 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PBP_sp32 PF07222.12 KXZ43503.1 - 4.4 6.7 8.6 7.1 6.0 8.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SR-25 PF10500.9 KXZ43503.1 - 6.9 6.2 35.0 3.3 7.3 23.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CAP PF00188.26 KXZ43504.1 - 7e-11 43.1 3.0 1.8e-10 41.7 3.0 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family EBP50_C PF09007.11 KXZ43504.1 - 0.046 14.7 0.9 0.065 14.2 0.9 1.2 1 0 0 1 1 1 0 EBP50, C-terminal DUF1180 PF06679.12 KXZ43504.1 - 0.2 12.1 1.5 0.25 11.8 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_M24 PF00557.24 KXZ43505.1 - 1.7e-47 161.9 0.0 2.2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXZ43505.1 - 1.6e-19 69.9 0.0 4.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CitMHS PF03600.16 KXZ43506.1 - 6e-47 160.3 22.1 1.4e-40 139.4 0.1 2.3 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 KXZ43506.1 - 2.7e-35 120.0 5.1 2.7e-10 39.9 0.0 4.4 4 0 0 4 4 4 4 TrkA-C domain Na_sulph_symp PF00939.19 KXZ43507.1 - 1.9e-05 23.9 5.3 1.9e-05 23.9 5.3 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXZ43507.1 - 3.5e-05 23.2 7.4 4.5e-05 22.8 7.4 1.1 1 0 0 1 1 1 1 Citrate transporter TrkA_C PF02080.21 KXZ43507.1 - 0.049 13.5 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-C domain CitMHS PF03600.16 KXZ43508.1 - 2.8e-45 154.8 27.7 4e-40 137.9 1.3 2.3 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 KXZ43508.1 - 7.6e-34 115.4 4.6 1.4e-08 34.5 0.0 4.4 4 0 0 4 4 4 4 TrkA-C domain E1-E2_ATPase PF00122.20 KXZ43508.1 - 5.5 6.5 6.5 1.7 8.1 2.1 2.5 3 0 0 3 3 3 0 E1-E2 ATPase TIP41 PF04176.13 KXZ43509.1 - 2.1e-53 180.3 0.0 5.4e-53 179.0 0.0 1.6 1 1 0 1 1 1 1 TIP41-like family DUF1906 PF08924.11 KXZ43509.1 - 0.86 9.7 3.9 1.8 8.7 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Ank_5 PF13857.6 KXZ43512.1 - 2.5e-26 91.4 3.4 3.1e-09 36.9 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43512.1 - 1.6e-24 86.3 3.6 4.3e-13 49.7 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43512.1 - 4.3e-23 80.7 4.2 2.5e-07 30.8 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KXZ43512.1 - 3.6e-22 78.4 2.3 7.6e-11 42.3 0.2 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43512.1 - 1.4e-13 49.6 2.4 0.0029 17.9 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ead_Ea22 PF13935.6 KXZ43512.1 - 0.0065 17.1 1.0 0.014 16.1 1.0 1.6 1 0 0 1 1 1 1 Ead/Ea22-like protein TFIIF_alpha PF05793.12 KXZ43512.1 - 2.6 6.6 16.2 0.3 9.6 10.8 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAD_binding_3 PF01494.19 KXZ43514.1 - 1.4e-16 60.7 6.4 4.7e-09 36.0 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain FHA PF00498.26 KXZ43514.1 - 1.5e-09 38.0 0.0 3.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain NAD_binding_8 PF13450.6 KXZ43514.1 - 0.00018 21.7 0.8 0.00076 19.7 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ43514.1 - 0.006 16.2 3.6 0.25 10.9 0.7 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase Yop-YscD_cpl PF16697.5 KXZ43514.1 - 0.008 16.5 0.0 0.12 12.7 0.0 2.4 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pyr_redox_2 PF07992.14 KXZ43514.1 - 0.05 12.8 3.0 0.086 12.1 0.1 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ43514.1 - 0.054 12.7 0.2 0.12 11.6 0.2 1.5 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 KXZ43514.1 - 0.21 10.6 0.0 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase PsaN PF05479.11 KXZ43515.1 - 5.9e-55 185.1 5.2 6.5e-55 184.9 5.2 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit N (PSAN or PSI-N) COX15-CtaA PF02628.15 KXZ43516.1 - 2e-15 56.7 0.9 2e-15 56.7 0.9 2.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein PsbX PF06596.11 KXZ43517.1 - 4.3e-18 65.0 0.5 4.3e-18 65.0 0.5 1.8 2 0 0 2 2 2 1 Photosystem II reaction centre X protein (PsbX) DUF4282 PF14110.6 KXZ43517.1 - 0.074 13.8 0.1 0.13 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Seryl_tRNA_N PF02403.22 KXZ43518.1 - 5.7e-20 71.5 0.4 9.9e-20 70.8 0.4 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain tRNA-synt_2b PF00587.25 KXZ43518.1 - 2.1e-18 66.9 0.0 1.6e-15 57.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) UCH PF00443.29 KXZ43521.1 - 5.7e-08 32.6 0.0 1.3e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CutA1 PF03091.15 KXZ43522.1 - 1.1e-15 57.3 0.0 1.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Herpes_capsid PF06112.11 KXZ43522.1 - 6.2 6.9 7.7 9.1 6.3 7.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SURF6 PF04935.12 KXZ43523.1 - 5.7e-29 101.3 51.0 5.7e-29 101.3 51.0 2.9 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KXZ43523.1 - 1e-13 51.6 3.1 1e-13 51.6 3.1 5.9 3 2 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 Sds3 PF08598.11 KXZ43523.1 - 1.4 8.8 15.3 0.052 13.5 8.1 2.1 2 1 0 2 2 2 0 Sds3-like GHMP_kinases_C PF08544.13 KXZ43524.1 - 3.4e-12 46.6 1.4 6.1e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KXZ43524.1 - 2.2e-08 34.2 7.3 5.6e-08 32.9 7.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain AAA_10 PF12846.7 KXZ43525.1 - 0.19 10.6 0.0 1.4 7.8 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_11 PF13086.6 KXZ43525.1 - 0.22 11.3 0.0 0.31 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain GHMP_kinases_C PF08544.13 KXZ43528.1 - 1.3e-08 35.1 0.9 1.5e-08 34.9 0.9 1.1 1 0 0 1 1 1 1 GHMP kinases C terminal LppC PF04348.13 KXZ43528.1 - 0.084 11.7 0.0 0.084 11.7 0.0 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein DUF5061 PF16587.5 KXZ43528.1 - 0.098 12.7 0.0 0.098 12.7 0.0 1.1 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein Ank_2 PF12796.7 KXZ43529.1 - 6.8e-10 39.4 0.0 1e-08 35.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43529.1 - 2.3e-09 36.7 0.0 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KXZ43529.1 - 1e-08 35.2 0.0 7.6e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXZ43529.1 - 5.5e-07 29.8 0.0 0.00018 21.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ43529.1 - 2.6e-06 27.9 0.0 3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NUDIX_4 PF14815.6 KXZ43531.1 - 0.00013 21.9 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 2 NUDIX domain DUF572 PF04502.13 KXZ43532.1 - 7.1e-49 167.2 1.6 8.7e-49 166.9 1.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) IRF-3 PF10401.9 KXZ43532.1 - 0.042 13.7 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-regulatory factor 3 GFA PF04828.14 KXZ43532.1 - 0.14 12.5 0.9 0.79 10.1 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme IR1-M PF12185.8 KXZ43533.1 - 0.57 10.2 1.5 0.9 9.5 0.5 1.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain 2OG-FeII_Oxy_3 PF13640.6 KXZ43534.1 - 2.9e-19 69.7 0.1 4.8e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ43534.1 - 0.00022 21.7 0.0 0.0005 20.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 KXZ43534.1 - 0.0043 17.5 0.4 0.0092 16.5 0.4 1.5 1 0 0 1 1 1 1 ShK domain-like Pox_C4_C10 PF03336.13 KXZ43534.1 - 0.04 13.0 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Topoisom_bac PF01131.20 KXZ43536.1 - 9.2e-103 344.4 0.0 1.1e-102 344.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KXZ43536.1 - 1.7e-11 44.3 0.0 4e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain NUDIX PF00293.28 KXZ43536.1 - 8.2e-08 32.4 2.5 2.6e-07 30.7 0.9 2.3 2 0 0 2 2 2 1 NUDIX domain Zn-ribbon_8 PF09723.10 KXZ43536.1 - 0.04 14.0 0.8 1.4 9.0 0.0 3.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-C4_Topoisom PF01396.19 KXZ43536.1 - 0.083 12.7 0.8 3.3 7.6 0.1 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.6 KXZ43536.1 - 0.39 10.2 2.8 0.45 10.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Alpha-amyl_C2 PF07821.12 KXZ43538.1 - 5.1e-19 68.2 0.0 9e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 KXZ43538.1 - 3.3e-11 43.4 0.0 2.1e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Agenet PF05641.12 KXZ43539.1 - 2.2e-07 31.2 0.1 3.4e-06 27.4 0.0 2.9 3 0 0 3 3 3 1 Agenet domain WD40 PF00400.32 KXZ43539.1 - 0.04 14.8 0.1 2.2 9.3 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Nop14 PF04147.12 KXZ43539.1 - 4.5 5.4 9.7 6.7 4.8 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family UBA PF00627.31 KXZ43540.1 - 5.4e-08 32.6 1.0 5.4e-08 32.6 1.0 1.6 2 0 0 2 2 2 1 UBA/TS-N domain Rhomboid PF01694.22 KXZ43540.1 - 0.015 15.3 4.3 0.024 14.7 4.3 1.3 1 0 0 1 1 1 0 Rhomboid family RuvA_C PF07499.13 KXZ43540.1 - 0.035 14.5 1.4 0.42 11.1 0.4 2.4 2 0 0 2 2 2 0 RuvA, C-terminal domain UBA_4 PF14555.6 KXZ43540.1 - 0.16 11.8 0.3 0.29 11.0 0.3 1.4 1 0 0 1 1 1 0 UBA-like domain Pkinase PF00069.25 KXZ43541.1 - 1.1e-66 224.9 0.0 1.3e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43541.1 - 2e-31 109.3 0.0 2.9e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ43541.1 - 0.00018 20.9 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ43541.1 - 0.0012 18.2 0.0 0.03 13.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXZ43541.1 - 0.015 14.3 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KXZ43541.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 EF-hand_7 PF13499.6 KXZ43542.1 - 9.4e-13 48.4 0.9 6.8e-09 36.1 0.1 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ43542.1 - 3.7e-10 38.6 0.2 0.001 18.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXZ43542.1 - 6.4e-10 38.2 0.0 0.00069 19.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KXZ43542.1 - 1.8e-09 36.7 1.3 0.00014 21.2 0.1 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KXZ43542.1 - 4.1e-05 23.9 0.1 0.36 11.2 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KXZ43542.1 - 0.024 14.5 0.1 4.7 7.1 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_4 PF12763.7 KXZ43542.1 - 0.044 13.7 0.9 1 9.4 0.3 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand LSM PF01423.22 KXZ43545.1 - 5.4e-18 64.4 0.2 6.6e-18 64.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXZ43545.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Hfq protein MmcB-like PF06319.12 KXZ43546.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein MmcB-like SET PF00856.28 KXZ43547.1 - 5.8e-11 43.1 0.0 8.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 SET domain Asparaginase PF00710.20 KXZ43548.1 - 7.8e-18 64.7 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXZ43548.1 - 6.8e-07 29.5 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain LRR_8 PF13855.6 KXZ43548.1 - 9.4e-07 28.5 0.3 9.4e-07 28.5 0.3 3.3 4 0 0 4 4 4 1 Leucine rich repeat Apt1 PF10351.9 KXZ43551.1 - 0.063 12.1 19.9 0.098 11.5 19.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KXZ43551.1 - 4.8 5.6 19.6 11 4.4 19.6 1.6 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 KXZ43551.1 - 8.5 5.0 12.0 14 4.3 12.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase PF00069.25 KXZ43554.1 - 5.5e-19 68.6 0.0 6.3e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43554.1 - 1.8e-09 37.3 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ43554.1 - 0.0099 15.8 0.1 0.019 14.9 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family TFIIA PF03153.13 KXZ43555.1 - 0.32 10.9 29.6 0.14 12.1 20.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-MYND PF01753.18 KXZ43557.1 - 3.9e-08 33.3 6.7 8.7e-08 32.1 6.7 1.6 1 0 0 1 1 1 1 MYND finger PAC4 PF16093.5 KXZ43558.1 - 0.068 13.4 0.4 1.4 9.2 0.4 2.3 2 1 0 2 2 2 0 Proteasome assembly chaperone 4 SNAP PF14938.6 KXZ43559.1 - 9e-21 74.5 9.4 1.1e-20 74.2 9.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KXZ43559.1 - 0.0011 19.2 10.9 0.31 11.4 4.6 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ43559.1 - 0.0038 16.7 1.3 0.24 10.7 1.1 3.0 1 1 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 KXZ43559.1 - 0.065 13.4 13.7 0.075 13.2 1.7 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ43559.1 - 0.32 11.5 0.1 0.32 11.5 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ43559.1 - 0.4 11.0 7.9 3.4 8.1 0.7 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 KXZ43559.1 - 3.2 6.6 5.1 0.86 8.5 1.0 1.9 1 1 1 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PPR PF01535.20 KXZ43559.1 - 8 7.0 7.9 60 4.2 0.0 4.4 5 0 0 5 5 5 0 PPR repeat Pkinase PF00069.25 KXZ43560.1 - 3.7e-28 98.6 0.0 7.9e-13 48.4 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43560.1 - 9.7e-23 80.8 0.0 5.1e-09 35.8 0.0 3.4 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43560.1 - 0.063 12.0 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXZ43560.1 - 0.24 10.7 0.0 0.38 10.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Tnp_22_dsRBD PF17490.2 KXZ43561.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain Pkinase PF00069.25 KXZ43562.1 - 1.6e-75 253.9 0.0 2.1e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43562.1 - 4.4e-34 117.9 0.0 6e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXZ43562.1 - 1.8e-07 30.5 0.0 2.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXZ43562.1 - 0.00055 19.3 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ43562.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ43562.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ43562.1 - 0.037 12.8 0.0 0.16 10.7 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KXZ43562.1 - 0.045 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 BolA PF01722.18 KXZ43563.1 - 9.1e-10 38.7 0.0 1.7e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein MutL_C PF08676.11 KXZ43563.1 - 0.028 14.2 0.1 0.068 12.9 0.0 1.6 2 0 0 2 2 2 0 MutL C terminal dimerisation domain RRM_1 PF00076.22 KXZ43565.1 - 2e-11 43.5 0.0 2.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TraD PF06412.11 KXZ43565.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.7 2 1 0 2 2 2 0 Conjugal transfer protein TraD ubiquitin PF00240.23 KXZ43567.1 - 2.2e-17 62.5 0.0 4.7e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXZ43567.1 - 1.8e-05 24.5 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Myc_N PF01056.18 KXZ43567.1 - 0.019 14.9 1.8 0.027 14.4 1.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF3246 PF11596.8 KXZ43567.1 - 0.13 11.6 0.5 0.21 11.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4677 PF15726.5 KXZ43567.1 - 1.7 8.8 7.1 3 8.0 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4677) Pkinase PF00069.25 KXZ43568.1 - 9.8e-24 84.1 0.0 1.6e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43568.1 - 3.8e-13 49.3 0.0 6.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ubiquitin PF00240.23 KXZ43568.1 - 1.5e-10 40.7 0.0 1e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Kinase-like PF14531.6 KXZ43568.1 - 2.9e-06 26.8 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rad60-SLD PF11976.8 KXZ43568.1 - 0.0089 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2249 PF10006.9 KXZ43568.1 - 0.2 11.5 1.8 31 4.5 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) SH3_9 PF14604.6 KXZ43569.1 - 1e-17 63.7 0.2 9.1e-08 31.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXZ43569.1 - 3.5e-17 61.8 0.0 2.8e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXZ43569.1 - 1.8e-10 40.3 0.0 0.00093 18.8 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain RAP1 PF07218.11 KXZ43569.1 - 5.6 5.1 6.0 8.3 4.5 6.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 KXZ43570.1 - 6.6e-47 160.1 0.0 1.9e-46 158.6 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43570.1 - 1.3e-44 152.4 0.0 7.5e-41 140.1 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ43570.1 - 0.00036 20.5 0.0 0.00086 19.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ43570.1 - 0.19 10.5 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase adh_short_C2 PF13561.6 KXZ43571.1 - 8.3e-41 140.1 8.6 1.4e-33 116.4 1.5 2.6 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ43571.1 - 3.4e-19 69.1 5.5 7.1e-13 48.4 0.1 3.3 2 2 1 3 3 3 3 short chain dehydrogenase KR PF08659.10 KXZ43571.1 - 0.011 15.7 4.6 0.41 10.5 0.0 2.6 2 1 1 3 3 3 0 KR domain Pkinase PF00069.25 KXZ43572.1 - 1.9e-09 37.3 0.0 2.2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43572.1 - 3.3e-07 29.9 0.0 4.1e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ43572.1 - 0.00092 18.6 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ43572.1 - 0.0022 17.9 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ43572.1 - 0.054 12.3 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXZ43572.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Guanylate_cyc PF00211.20 KXZ43573.1 - 1.9e-54 184.1 0.0 2.7e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PITH PF06201.13 KXZ43574.1 - 7.8e-30 104.1 0.0 8.9e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 PITH domain PCI PF01399.27 KXZ43575.1 - 1.4e-07 32.0 0.0 2.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 PCI domain C2 PF00168.30 KXZ43576.1 - 5.2e-18 65.2 0.0 6.7e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain DnaJ PF00226.31 KXZ43577.1 - 6.8e-17 61.4 0.3 1.4e-16 60.4 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Peptidase_M3 PF01432.20 KXZ43578.1 - 1.2e-06 28.1 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 Guanylate_cyc PF00211.20 KXZ43579.1 - 3.4e-50 170.2 0.0 4.8e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ43580.1 - 2.3e-50 170.8 0.0 2.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ldh_1_C PF02866.18 KXZ43581.1 - 3.4e-20 72.6 0.0 4.2e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Guanylate_cyc PF00211.20 KXZ43582.1 - 6.2e-29 100.9 0.0 5.3e-19 68.5 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Mlo PF03094.15 KXZ43583.1 - 8.8e-22 77.1 15.8 4.2e-12 45.2 2.0 3.1 3 0 0 3 3 3 3 Mlo family EF-hand_1 PF00036.32 KXZ43583.1 - 4.7e-10 38.3 2.3 1.4e-05 24.3 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXZ43583.1 - 1.5e-09 38.2 0.1 5.4e-09 36.4 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ43583.1 - 1.3e-08 34.6 4.7 3.1e-06 26.9 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ43583.1 - 6.9e-08 31.8 2.1 1.2e-05 24.8 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KXZ43583.1 - 0.0073 15.8 0.5 0.021 14.3 0.5 1.8 1 0 0 1 1 1 1 EF hand SR-25 PF10500.9 KXZ43583.1 - 9.4 5.8 12.1 16 5.0 12.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SBP PF03110.14 KXZ43584.1 - 3.4e-16 59.3 16.3 5.7e-16 58.6 16.3 1.3 1 0 0 1 1 1 1 SBP domain Gar1 PF04410.14 KXZ43585.1 - 1.9e-28 99.2 0.0 3.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region BACK PF07707.15 KXZ43585.1 - 8.4e-13 48.3 0.1 6.6e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ43585.1 - 5e-06 26.7 0.0 0.00016 21.9 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain B56 PF01603.20 KXZ43586.1 - 7.9e-190 631.2 5.4 9.2e-190 631.0 5.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Adaptin_N PF01602.20 KXZ43586.1 - 0.054 12.0 0.5 0.15 10.6 0.1 1.9 2 1 0 2 2 2 0 Adaptin N terminal region Prp18 PF02840.15 KXZ43587.1 - 3.6e-54 182.7 0.8 3.6e-54 182.7 0.8 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KXZ43587.1 - 3.1e-13 49.0 1.0 3.1e-13 49.0 1.0 2.4 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Histone PF00125.24 KXZ43588.1 - 2.4e-17 63.5 0.0 3.1e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KXZ43588.1 - 7.3e-13 48.0 0.7 1.5e-12 47.0 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KXZ43588.1 - 0.00085 19.6 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Methyltransf_5 PF01795.19 KXZ43589.1 - 1.5e-91 307.1 0.0 1.8e-91 306.8 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 KXZ43589.1 - 0.058 14.1 0.0 0.25 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain bZIP_1 PF00170.21 KXZ43590.1 - 0.00055 20.0 10.0 0.00055 20.0 10.0 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ43590.1 - 0.028 14.5 13.4 0.028 14.5 13.4 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Fib_alpha PF08702.10 KXZ43590.1 - 0.37 11.0 1.7 0.6 10.3 1.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CDC45 PF02724.14 KXZ43590.1 - 2.8 6.1 8.9 3.7 5.7 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein AC_N PF16214.5 KXZ43590.1 - 8.1 5.5 7.8 12 4.9 7.8 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Thioesterase PF00975.20 KXZ43592.1 - 7.1e-18 65.6 1.7 8.4e-17 62.1 1.7 2.1 1 1 0 1 1 1 1 Thioesterase domain Beta-lactamase PF00144.24 KXZ43592.1 - 2.9e-17 62.9 7.8 1.6e-16 60.5 4.2 3.2 1 1 0 2 2 2 1 Beta-lactamase Peptidase_M41 PF01434.18 KXZ43593.1 - 2.1e-67 226.7 2.9 7e-67 225.0 1.7 2.1 1 1 1 2 2 2 1 Peptidase family M41 AAA PF00004.29 KXZ43593.1 - 5.9e-42 143.2 0.0 1.7e-41 141.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ43593.1 - 4.7e-12 45.5 0.0 1.1e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ43593.1 - 4.5e-07 29.9 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXZ43593.1 - 1.5e-05 24.8 0.0 3.9e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ43593.1 - 1.9e-05 25.1 1.6 0.0015 18.9 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 KXZ43593.1 - 6.4e-05 22.3 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXZ43593.1 - 0.00016 22.0 1.1 0.025 14.9 0.1 3.5 3 1 1 4 4 4 1 AAA domain NACHT PF05729.12 KXZ43593.1 - 0.00074 19.5 0.2 0.023 14.6 0.1 2.7 2 1 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 KXZ43593.1 - 0.0016 18.2 0.2 0.0067 16.2 0.1 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXZ43593.1 - 0.0018 17.7 1.0 0.0044 16.4 0.2 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXZ43593.1 - 0.0022 18.1 0.0 0.0063 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXZ43593.1 - 0.0026 18.0 0.6 0.055 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXZ43593.1 - 0.0033 17.0 4.0 0.24 10.9 0.2 3.5 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 KXZ43593.1 - 0.013 15.0 0.1 0.087 12.3 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KXZ43593.1 - 0.015 15.8 0.0 0.042 14.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.14 KXZ43593.1 - 0.015 15.4 0.1 0.073 13.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 KXZ43593.1 - 0.026 13.9 0.1 0.98 8.7 0.0 2.4 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 KXZ43593.1 - 0.033 14.2 0.1 0.15 12.0 0.0 2.1 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KXZ43593.1 - 0.048 12.9 2.9 0.28 10.4 0.6 2.7 2 1 1 3 3 3 0 Zeta toxin ABC_tran PF00005.27 KXZ43593.1 - 0.062 13.8 1.0 0.26 11.8 0.4 2.2 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KXZ43593.1 - 0.077 12.7 0.1 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXZ43593.1 - 0.083 13.3 0.1 0.23 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 KXZ43593.1 - 0.097 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXZ43593.1 - 0.11 12.2 0.0 0.41 10.3 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain Peptidase_M50B PF13398.6 KXZ43593.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Parvo_NS1 PF01057.17 KXZ43593.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Kinesin PF00225.23 KXZ43594.1 - 1.6e-106 356.0 0.0 1.6e-106 356.0 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ43594.1 - 1.5e-23 83.4 0.2 1.8e-22 79.9 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding COG5 PF10392.9 KXZ43594.1 - 0.0024 18.0 7.7 0.0024 18.0 7.7 9.0 6 4 3 10 10 10 1 Golgi transport complex subunit 5 HMMR_N PF15905.5 KXZ43594.1 - 0.0033 17.0 39.8 0.0033 17.0 39.8 9.6 2 2 6 8 8 8 2 Hyaluronan mediated motility receptor N-terminal DUF1154 PF06631.11 KXZ43594.1 - 0.013 15.6 3.4 0.72 9.9 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) DUF92 PF01940.16 KXZ43595.1 - 2.5e-26 92.5 15.4 2.5e-26 92.5 15.4 2.5 1 1 1 2 2 2 2 Integral membrane protein DUF92 UQ_con PF00179.26 KXZ43596.1 - 1.5e-46 157.6 0.0 1.6e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXZ43596.1 - 0.0014 18.9 0.1 0.0016 18.7 0.0 1.3 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KXZ43596.1 - 0.0039 16.9 0.0 0.0052 16.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Lipase_GDSL_2 PF13472.6 KXZ43596.1 - 0.049 14.0 0.1 0.08 13.3 0.1 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family UFC1 PF08694.11 KXZ43596.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 adh_short_C2 PF13561.6 KXZ43597.1 - 8.6e-51 172.7 3.6 7e-47 159.9 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ43597.1 - 6.5e-11 42.1 1.4 3.9e-08 33.0 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.8 KXZ43597.1 - 0.027 13.8 0.1 0.098 12.0 0.0 1.8 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region Nicastrin PF05450.15 KXZ43598.1 - 3.5e-42 144.5 0.3 5e-42 144.0 0.3 1.2 1 0 0 1 1 1 1 Nicastrin NR_Repeat PF14046.6 KXZ43598.1 - 0.23 11.6 3.8 1.5 9.0 0.6 2.5 2 0 0 2 2 2 0 Nuclear receptor repeat RRM_1 PF00076.22 KXZ43600.1 - 7e-43 144.3 0.1 1.1e-16 60.4 0.0 4.7 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPO22 PF08631.10 KXZ43601.1 - 1.8e-05 24.4 0.7 0.0017 17.9 0.6 2.5 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 KXZ43601.1 - 1.2 9.4 16.6 6.6 7.1 1.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ43601.1 - 4.5 8.1 8.0 81 4.2 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Aminotran_5 PF00266.19 KXZ43603.1 - 2.5e-10 39.9 0.0 0.00083 18.4 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXZ43603.1 - 0.00014 21.2 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXZ43603.1 - 0.00044 19.7 0.1 0.66 9.2 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_M43 PF05572.13 KXZ43603.1 - 0.11 12.4 0.3 0.2 11.5 0.3 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Pkinase PF00069.25 KXZ43604.1 - 1.8e-42 145.5 0.0 1.1e-39 136.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43604.1 - 9.9e-42 143.0 0.0 1e-38 133.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ43604.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ43604.1 - 0.0089 14.9 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pribosyltran PF00156.27 KXZ43605.1 - 2.9e-16 59.4 0.0 3.1e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KXZ43605.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Mitofilin PF09731.9 KXZ43606.1 - 0.0022 16.9 9.0 0.0022 16.9 9.0 2.9 2 1 1 3 3 3 1 Mitochondrial inner membrane protein T2SSM_b PF10741.9 KXZ43607.1 - 2.3 8.0 10.4 9.7 6.0 1.1 2.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b zf-C3HC4_3 PF13920.6 KXZ43608.1 - 5.7e-05 22.9 12.3 7.7e-05 22.5 12.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 KXZ43609.1 - 0.007 15.8 0.7 0.91 8.8 0.2 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) UPF0564 PF10595.9 KXZ43609.1 - 0.12 11.4 2.5 0.18 10.9 0.2 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0564 DUF563 PF04577.14 KXZ43611.1 - 1.4e-11 44.9 0.0 6.2e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Mito_carr PF00153.27 KXZ43612.1 - 1.2e-29 102.1 12.6 1.3e-14 53.8 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein ICL PF00463.21 KXZ43613.1 - 1.2e-99 334.2 1.3 1.2e-49 169.3 0.7 2.1 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 KXZ43613.1 - 1.5e-18 67.2 0.3 6.1e-18 65.1 0.3 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF3267 PF11667.8 KXZ43614.1 - 0.0062 16.8 0.8 0.0062 16.8 0.8 1.9 2 0 0 2 2 2 1 Putative zincin peptidase PAS_9 PF13426.7 KXZ43615.1 - 1.4e-06 28.5 0.0 0.0038 17.5 0.0 4.0 4 0 0 4 4 4 1 PAS domain PAS_4 PF08448.10 KXZ43615.1 - 0.00025 21.3 0.0 2.9 8.2 0.0 4.8 5 0 0 5 5 5 1 PAS fold PAS PF00989.25 KXZ43615.1 - 0.00051 20.0 0.0 2.8 8.0 0.0 3.9 4 0 0 4 4 4 2 PAS fold Pkinase PF00069.25 KXZ43617.1 - 9e-15 54.7 0.0 3e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43617.1 - 3.1e-11 43.0 0.0 6.9e-11 41.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43617.1 - 4.5e-05 22.4 0.0 5.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ43617.1 - 0.0058 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ43617.1 - 0.027 14.4 3.6 0.06 13.2 3.6 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ43618.1 - 1.9e-05 24.1 0.0 2e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ43619.1 - 1.1e-19 70.8 0.0 1.2e-10 41.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ43619.1 - 4.4e-14 52.5 0.0 5.4e-12 45.6 0.0 3.0 2 1 1 3 3 3 1 Protein kinase domain Kdo PF06293.14 KXZ43619.1 - 0.004 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ43619.1 - 0.027 14.4 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXZ43619.1 - 0.071 12.7 0.0 1.4 8.5 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KXZ43620.1 - 1.2e-16 60.9 0.0 1.3e-14 54.2 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43620.1 - 6.2e-14 51.9 0.0 4.8e-11 42.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KXZ43620.1 - 0.005 16.2 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ43620.1 - 0.08 12.9 6.5 0.24 11.3 6.5 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mlo PF03094.15 KXZ43621.1 - 8.4e-11 40.9 0.0 1.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Mlo family Mlo PF03094.15 KXZ43622.1 - 1.1e-41 142.7 6.1 2.8e-26 91.9 0.8 2.2 1 1 1 2 2 2 2 Mlo family Ank_4 PF13637.6 KXZ43623.1 - 2.8e-07 30.9 1.3 0.034 14.7 0.0 4.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43623.1 - 0.00064 20.3 0.4 0.56 10.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ43623.1 - 7.9 6.9 6.6 1.2e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Apt1 PF10351.9 KXZ43624.1 - 4.7e-08 32.3 0.0 0.00025 20.1 0.0 2.6 2 1 0 2 2 2 2 Golgi-body localisation protein domain C166 PF17615.2 KXZ43624.1 - 0.32 11.1 2.5 0.38 10.9 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function EF-hand_1 PF00036.32 KXZ43625.1 - 0.00015 21.0 0.0 0.00033 20.0 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ43625.1 - 0.0061 17.0 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ43625.1 - 0.0061 16.0 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43625.1 - 0.0075 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXZ43625.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair BHD_3 PF10405.9 KXZ43625.1 - 0.17 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 VOMI PF03762.17 KXZ43625.1 - 0.19 11.9 0.2 1.4 9.0 0.2 2.1 1 1 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) Tmemb_170 PF10190.9 KXZ43625.1 - 0.37 11.2 5.0 2.8 8.3 1.1 2.6 2 0 0 2 2 2 0 Putative transmembrane protein 170 RicinB_lectin_2 PF14200.6 KXZ43626.1 - 4e-39 133.2 17.9 7.2e-16 58.7 0.8 4.7 1 1 4 5 5 5 5 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ43626.1 - 7.6e-34 116.7 7.2 2.1e-15 57.1 2.1 3.3 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ43626.1 - 7.6e-16 58.7 0.8 7.6e-16 58.7 0.8 2.2 3 0 0 3 3 3 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ43626.1 - 2.2e-07 30.6 10.8 0.00044 19.9 0.9 2.8 1 1 0 2 2 2 2 Cytolethal distending toxin A/C domain Sulfotransfer_3 PF13469.6 KXZ43627.1 - 2.4e-18 67.3 1.3 4.9e-08 33.6 0.2 2.2 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KXZ43627.1 - 0.022 14.2 0.0 3.1 7.2 0.0 2.2 1 1 0 2 2 2 0 Sulfotransferase domain EF-hand_1 PF00036.32 KXZ43628.1 - 6e-06 25.4 0.0 1.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43628.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ43628.1 - 0.00017 21.9 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ43628.1 - 0.00019 20.8 0.0 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ43628.1 - 0.0053 16.6 0.0 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair L27 PF02828.16 KXZ43628.1 - 0.028 14.2 0.5 0.042 13.6 0.5 1.3 1 0 0 1 1 1 0 L27 domain HET-S PF17108.5 KXZ43629.1 - 0.095 12.5 0.1 0.29 10.9 0.1 1.9 1 0 0 1 1 1 0 N-terminal small S protein of HET, non-prionic VOMI PF03762.17 KXZ43631.1 - 0.0022 18.1 0.4 0.14 12.2 0.3 2.0 1 1 1 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) RicinB_lectin_2 PF14200.6 KXZ43632.1 - 5.2e-13 49.5 0.0 7.6e-09 36.2 0.0 1.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ43632.1 - 4.1e-08 33.5 0.0 1.9e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ank_2 PF12796.7 KXZ43633.1 - 1e-11 45.3 0.1 1.5e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43633.1 - 4.5e-10 39.9 0.1 8.4e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43633.1 - 9e-08 31.8 0.2 0.00044 20.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KXZ43633.1 - 9.7e-08 32.1 2.6 0.0011 19.3 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Abhydrolase_6 PF12697.7 KXZ43633.1 - 1.8e-07 32.0 3.9 2.2e-07 31.7 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_5 PF13857.6 KXZ43633.1 - 1.1e-06 28.7 2.0 7.4e-05 23.0 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF676 PF05057.14 KXZ43633.1 - 2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 KXZ43633.1 - 0.0012 18.7 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KXZ43633.1 - 0.0034 17.1 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 KXZ43633.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 KXZ43633.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 KXZ43633.1 - 0.18 11.6 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ank_2 PF12796.7 KXZ43634.1 - 5.1e-93 305.8 31.9 1.6e-18 67.1 3.5 7.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43634.1 - 1.8e-76 251.6 16.8 8.7e-11 42.1 0.0 9.6 6 2 5 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43634.1 - 2e-75 239.7 18.7 0.00012 22.3 0.0 15.8 15 0 0 15 15 15 15 Ankyrin repeat Ank PF00023.30 KXZ43634.1 - 6.4e-71 231.9 56.3 2.6e-06 27.6 0.1 15.6 15 0 0 15 15 15 15 Ankyrin repeat Ank_5 PF13857.6 KXZ43634.1 - 2.1e-60 200.0 43.2 1.3e-09 38.1 0.1 13.6 3 2 12 15 15 15 14 Ankyrin repeats (many copies) COR PF16095.5 KXZ43634.1 - 5.2e-13 49.2 0.0 8.3e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Dickkopf_N PF04706.12 KXZ43636.1 - 1.7 9.2 11.5 3.7 8.1 1.8 3.9 2 2 1 3 3 3 0 Dickkopf N-terminal cysteine-rich region ABC_tran PF00005.27 KXZ43637.1 - 3.3e-05 24.4 0.0 9.5e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter CheB_methylest PF01339.17 KXZ43637.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 CheB methylesterase AAA_21 PF13304.6 KXZ43637.1 - 0.17 11.7 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ank_4 PF13637.6 KXZ43638.1 - 1.1e-70 233.1 3.7 6.9e-11 42.5 0.0 7.0 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43638.1 - 5.5e-63 209.5 12.7 1e-13 51.6 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ43638.1 - 1.4e-57 189.8 10.7 3e-05 24.3 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 KXZ43638.1 - 1.6e-55 178.6 0.0 8e-05 22.7 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 KXZ43638.1 - 1.5e-46 155.8 23.2 3.6e-07 30.3 0.1 7.7 1 1 8 9 9 9 9 Ankyrin repeats (many copies) MGS PF02142.22 KXZ43638.1 - 9.8e-05 22.5 0.3 2 8.6 0.1 3.7 2 2 0 3 3 3 2 MGS-like domain DUF1018 PF06252.12 KXZ43638.1 - 0.00031 21.7 13.4 1.4 9.9 0.8 4.4 1 1 3 4 4 4 3 Protein of unknown function (DUF1018) GUN4_N PF16416.5 KXZ43638.1 - 0.00032 20.6 1.5 71 3.5 0.0 5.7 2 2 4 6 6 6 0 ARM-like repeat domain, GUN4-N terminal Ribosomal_S3_C PF00189.20 KXZ43638.1 - 0.19 12.3 3.0 52 4.5 0.0 4.5 3 2 3 6 6 6 0 Ribosomal protein S3, C-terminal domain DUF4988 PF16378.5 KXZ43638.1 - 0.8 9.3 3.4 70 3.0 0.0 4.3 1 1 4 6 6 6 0 Domain of unknown function DUF1387 PF07139.11 KXZ43638.1 - 2 8.1 3.8 7.3 6.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1387) Roc PF08477.13 KXZ43639.1 - 1.3e-17 64.1 0.0 2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ43639.1 - 1.2e-16 61.2 0.0 1.9e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 KXZ43639.1 - 1e-08 35.0 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 KXZ43639.1 - 2.9e-08 34.2 0.0 8.4e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Arf PF00025.21 KXZ43639.1 - 7.5e-08 32.0 0.0 1.6e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Ank_5 PF13857.6 KXZ43639.1 - 2.5e-07 30.8 0.0 6.8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43639.1 - 1e-06 28.9 0.1 0.0031 17.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXZ43639.1 - 4e-05 23.7 0.0 0.017 15.6 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat AAA_25 PF13481.6 KXZ43639.1 - 0.0062 16.1 0.1 0.02 14.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXZ43639.1 - 0.0073 15.7 0.2 0.015 14.7 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Ank_4 PF13637.6 KXZ43639.1 - 0.0077 16.8 0.0 0.42 11.2 0.0 3.1 2 1 0 3 3 3 1 Ankyrin repeats (many copies) AAA_33 PF13671.6 KXZ43639.1 - 0.0081 16.3 0.0 0.034 14.3 0.0 2.1 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KXZ43639.1 - 0.035 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 KXZ43639.1 - 0.036 14.6 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXZ43639.1 - 0.064 13.5 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ43639.1 - 0.069 13.5 2.2 0.15 12.4 0.1 2.6 3 1 0 3 3 3 0 AAA ATPase domain PhoH PF02562.16 KXZ43639.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein UCH PF00443.29 KXZ43640.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KXZ43645.1 - 3e-27 95.8 0.0 3.7e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ43645.1 - 3.4e-08 33.5 0.0 5.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TRP PF06011.12 KXZ43646.1 - 0.00074 18.4 1.5 0.00074 18.4 1.5 1.5 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel Chlam_PMP PF02415.17 KXZ43647.1 - 7.9e-06 26.0 24.5 0.14 12.7 2.2 4.8 4 0 0 4 4 4 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 KXZ43647.1 - 0.016 15.1 14.6 0.033 14.1 14.6 1.4 1 1 0 1 1 1 0 Right handed beta helix region DUF5114 PF17141.4 KXZ43647.1 - 0.1 13.2 3.0 1.4 9.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5114) Gp5_C PF06715.12 KXZ43647.1 - 0.94 9.8 9.4 3.5 8.0 0.3 4.6 4 2 0 4 4 4 0 Gp5 C-terminal repeat (3 copies) DctQ PF04290.12 KXZ43648.1 - 0.031 14.2 6.3 0.058 13.3 5.6 1.7 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component TRP PF06011.12 KXZ43649.1 - 2e-09 36.7 22.0 8.1e-08 31.4 2.8 2.7 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel Adeno_100 PF02438.16 KXZ43649.1 - 0.0074 14.5 0.0 0.88 7.7 0.0 2.1 2 0 0 2 2 2 2 Late 100kD protein RinB PF06116.12 KXZ43649.1 - 0.013 15.6 0.6 36 4.6 0.0 3.5 3 0 0 3 3 3 0 Transcriptional activator RinB SUIM_assoc PF16619.5 KXZ43651.1 - 0.11 12.6 3.2 0.3 11.2 3.2 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 KAAG1 PF15354.6 KXZ43654.1 - 0.017 15.6 0.4 0.042 14.4 0.1 1.9 2 0 0 2 2 2 0 Kidney-associated antigen 1 DUF481 PF04338.12 KXZ43654.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF481 FAD_binding_3 PF01494.19 KXZ43656.1 - 3.2e-10 39.8 3.8 0.0004 19.8 0.4 3.1 2 2 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXZ43656.1 - 1.5e-07 31.5 0.3 3.8e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ43656.1 - 2.2e-05 23.9 0.1 0.0077 15.5 0.0 1.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ43656.1 - 0.00013 21.7 2.1 0.00018 21.2 2.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXZ43656.1 - 0.00069 20.1 0.1 0.0034 17.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ43656.1 - 0.0018 17.4 0.3 0.0018 17.4 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXZ43656.1 - 0.023 13.9 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXZ43656.1 - 0.04 12.6 0.1 0.057 12.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KXZ43656.1 - 0.1 11.7 0.8 0.16 11.0 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 KXZ43658.1 - 1.4e-15 57.1 65.8 2.7e-15 56.2 56.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_A22B PF04258.13 KXZ43659.1 - 2.1e-78 263.7 5.4 2.4e-78 263.6 5.4 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KXZ43659.1 - 4.3e-06 26.4 7.7 4.3e-06 26.4 7.7 2.3 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Nucleotid_trans PF03407.16 KXZ43660.1 - 2.6e-46 158.3 0.0 3.7e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase LpxD PF04613.14 KXZ43660.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD NMT1 PF09084.11 KXZ43661.1 - 2.6e-52 177.9 0.0 3.5e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KXZ43661.1 - 0.059 13.1 1.5 1.2 8.7 0.0 2.4 2 1 0 2 2 2 0 NMT1-like family Glyco_hydro_20 PF00728.22 KXZ43662.1 - 0.046 13.1 0.1 0.057 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20 PF00728.22 KXZ43663.1 - 0.0046 16.4 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Pkinase PF00069.25 KXZ43664.1 - 3.4e-15 56.1 0.0 6.4e-14 52.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43664.1 - 1.2e-14 54.2 0.0 3.3e-10 39.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ43664.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp_protease_2 PF13650.6 KXZ43666.1 - 0.00017 22.2 0.1 0.0003 21.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXZ43666.1 - 0.012 16.2 0.1 0.021 15.3 0.1 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 KXZ43666.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Hint PF01079.20 KXZ43667.1 - 2.6e-11 43.4 0.0 2.4e-10 40.3 0.0 2.1 1 1 1 2 2 2 1 Hint module EF-hand_5 PF13202.6 KXZ43667.1 - 0.00054 19.3 0.2 0.0011 18.4 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ43667.1 - 0.0014 18.1 0.1 0.0025 17.3 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ43667.1 - 0.0035 17.1 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ43667.1 - 0.077 13.5 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair LPD26 PF18842.1 KXZ43668.1 - 1 9.4 3.3 23 5.0 0.5 2.8 1 1 2 3 3 3 0 Large polyvalent protein associated domain 26 Pkinase PF00069.25 KXZ43669.1 - 1.1e-13 51.2 0.0 5.7e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43669.1 - 5.4e-12 45.5 0.0 1.8e-07 30.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Complex1_LYR PF05347.15 KXZ43671.1 - 8.4e-05 22.6 0.3 0.00016 21.7 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1974 PF09317.11 KXZ43671.1 - 0.064 12.8 0.2 0.07 12.7 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) COX14 PF14880.6 KXZ43673.1 - 0.0033 17.2 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Ribosomal_S13_N PF08069.12 KXZ43674.1 - 1.7e-30 104.8 0.2 3.3e-30 103.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KXZ43674.1 - 2.8e-14 53.1 0.2 4.7e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PfkB PF00294.24 KXZ43676.1 - 2.1e-41 142.2 0.2 4e-41 141.3 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ank_2 PF12796.7 KXZ43677.1 - 8.7e-11 42.3 0.3 1.9e-08 34.7 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43677.1 - 0.0067 17.0 5.7 1.9 9.1 0.2 4.7 2 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43677.1 - 0.33 11.6 5.0 45 5.1 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 KXZ43677.1 - 0.98 9.8 5.0 18 5.8 0.3 4.1 1 1 4 5 5 5 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43677.1 - 7.7 7.2 10.1 11 6.7 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 KXZ43678.1 - 1.5e-12 47.9 0.2 6.7e-09 36.2 0.1 3.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43678.1 - 4.6e-05 23.9 5.3 0.18 12.4 0.4 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43678.1 - 0.011 16.0 2.6 20 5.7 0.1 3.9 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43678.1 - 0.043 14.3 4.8 3.8 8.1 0.1 3.6 3 1 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 KXZ43678.1 - 0.051 14.1 2.9 9.6 7.2 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeat NTP_transferase PF00483.23 KXZ43680.1 - 1.5e-42 145.9 0.0 1.9e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KXZ43680.1 - 7.3e-06 25.5 8.6 0.021 14.5 0.7 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ43680.1 - 0.039 13.7 6.2 0.55 10.0 0.4 2.9 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase KH_1 PF00013.29 KXZ43683.1 - 9.9e-08 31.7 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 KH domain Exo_endo_phos PF03372.23 KXZ43685.1 - 3.6e-14 52.9 0.8 1.3e-13 51.0 0.2 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family MIB_HERC2 PF06701.13 KXZ43686.1 - 1.2e-17 63.9 23.9 3e-10 40.2 5.9 4.1 3 1 0 3 3 3 2 Mib_herc2 U-box PF04564.15 KXZ43686.1 - 1.3e-15 57.4 0.0 2.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXZ43686.1 - 2.2e-06 27.4 0.0 6.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KXZ43687.1 - 2e-17 63.1 0.0 4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain MIB_HERC2 PF06701.13 KXZ43687.1 - 1e-09 38.5 4.7 2e-08 34.3 1.1 2.5 2 0 0 2 2 2 2 Mib_herc2 zf-Nse PF11789.8 KXZ43687.1 - 2e-06 27.5 0.0 4.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXZ43687.1 - 0.0043 17.0 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger DUF2559 PF10832.8 KXZ43687.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) Pkinase_Tyr PF07714.17 KXZ43688.1 - 2.8e-05 23.6 0.0 0.00016 21.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ43688.1 - 0.00013 21.5 0.0 0.0002 20.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain MDMPI_N PF11716.8 KXZ43688.1 - 0.0052 17.5 3.0 0.0062 17.2 3.0 1.2 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain Ion_trans PF00520.31 KXZ43689.1 - 2.1e-09 37.0 5.4 1.8e-07 30.6 8.3 2.1 2 0 0 2 2 2 1 Ion transport protein Phage_holin_3_6 PF07332.11 KXZ43689.1 - 0.083 12.9 0.0 0.083 12.9 0.0 3.2 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Hydrolase_4 PF12146.8 KXZ43690.1 - 1.3e-28 99.9 0.2 1.3e-15 57.3 0.7 3.2 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ43690.1 - 1.1e-08 35.1 0.1 5.5e-05 22.9 0.4 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pkinase PF00069.25 KXZ43691.1 - 7.3e-41 140.3 0.0 2.3e-39 135.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43691.1 - 1e-39 136.4 0.0 1e-38 133.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXZ43691.1 - 0.0035 17.3 0.0 0.0091 15.9 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ43691.1 - 0.031 13.1 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 KXZ43692.1 - 2.3e-06 27.4 2.7 8.5e-06 25.6 2.7 2.0 1 1 0 1 1 1 1 F-box-like FYDLN_acid PF09538.10 KXZ43692.1 - 0.071 13.8 0.1 0.071 13.8 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) F-box PF00646.33 KXZ43692.1 - 0.32 10.9 0.8 0.68 9.9 0.8 1.5 1 0 0 1 1 1 0 F-box domain SUIM_assoc PF16619.5 KXZ43692.1 - 0.91 9.6 13.2 2.3 8.3 13.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Mg_trans_NIPA PF05653.14 KXZ43693.1 - 0.14 11.3 4.3 0.046 12.8 0.9 1.9 1 1 0 1 1 1 0 Magnesium transporter NIPA CPP1-like PF11833.8 KXZ43693.1 - 7.1 6.2 7.2 8.5 6.0 6.1 1.7 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CPDase PF07823.11 KXZ43694.1 - 9.7e-11 41.7 0.0 1e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KXZ43694.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KXZ43694.1 - 0.072 13.3 3.4 0.08 13.1 0.0 2.4 3 0 0 3 3 3 0 LigT like Phosphoesterase Cupin_8 PF13621.6 KXZ43695.1 - 1.4e-35 123.2 0.0 3.4e-35 122.0 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXZ43695.1 - 1e-10 41.6 0.0 1.9e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KXZ43695.1 - 4.1e-05 24.0 0.0 0.0015 19.0 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase ISPD_C PF18706.1 KXZ43696.1 - 0.057 13.1 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Glyco_transf_90 PF05686.12 KXZ43697.1 - 1.4e-29 103.2 0.0 2.6e-29 102.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Myb_DNA-bind_6 PF13921.6 KXZ43698.1 - 2.7e-06 27.5 0.1 3.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXZ43698.1 - 3.3e-06 27.2 0.1 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXZ43698.1 - 0.048 13.5 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like BUD22 PF09073.10 KXZ43698.1 - 6.8 5.9 13.5 17 4.6 13.5 1.6 1 0 0 1 1 1 0 BUD22 Prok-RING_4 PF14447.6 KXZ43699.1 - 0.0043 16.9 3.8 0.025 14.4 0.1 2.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 PLATZ PF04640.14 KXZ43699.1 - 0.028 15.1 1.3 0.028 15.1 1.3 1.4 2 0 0 2 2 2 0 PLATZ transcription factor zf-MYND PF01753.18 KXZ43699.1 - 0.58 10.3 8.4 0.17 12.0 2.8 2.2 2 0 0 2 2 2 0 MYND finger zf-FLZ PF04570.14 KXZ43699.1 - 1.2 8.7 9.0 2.2 7.8 7.3 2.1 2 1 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 DUF4217 PF13959.6 KXZ43700.1 - 6.5e-16 58.3 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) MRP-S34 PF16053.5 KXZ43701.1 - 2.5e-12 46.6 0.0 2.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Ank_2 PF12796.7 KXZ43702.1 - 7.4e-32 109.8 0.6 2.6e-17 63.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ43702.1 - 1.3e-26 92.3 2.2 1.4e-11 44.4 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ43702.1 - 3.4e-23 81.0 7.1 6.9e-08 32.6 1.3 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXZ43702.1 - 2.4e-22 79.0 0.1 3.1e-11 43.6 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43702.1 - 6.1e-21 72.3 0.5 7.9e-07 28.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat DUF4248 PF14053.6 KXZ43704.1 - 0.052 13.6 0.1 3.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF3479 PF11965.8 KXZ43704.1 - 0.08 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) ParD PF09386.10 KXZ43704.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Antitoxin ParD TraF_2 PF13729.6 KXZ43704.1 - 0.22 10.9 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Pkinase PF00069.25 KXZ43705.1 - 4.5e-05 22.9 0.0 0.0002 20.8 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain SET PF00856.28 KXZ43706.1 - 1.4e-13 51.6 0.0 3.9e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 SET domain Peroxin-22 PF12827.7 KXZ43707.1 - 0.26 11.2 0.0 0.38 10.7 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family NUDE_C PF04880.13 KXZ43707.1 - 1.2 9.6 4.2 1.6 9.1 4.2 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FAM183 PF14886.6 KXZ43708.1 - 0.0027 18.4 0.1 0.0044 17.7 0.1 1.3 1 0 0 1 1 1 1 FAM183A and FAM183B related EF-hand_7 PF13499.6 KXZ43708.1 - 0.0056 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ43708.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KXZ43708.1 - 0.025 14.1 0.1 0.051 13.1 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_9 PF14658.6 KXZ43708.1 - 0.042 14.2 0.0 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_6 PF13405.6 KXZ43708.1 - 0.14 12.1 1.1 0.26 11.3 0.1 2.0 3 0 0 3 3 3 0 EF-hand domain Chloroa_b-bind PF00504.21 KXZ43709.1 - 7.4e-45 153.4 0.3 9.4e-45 153.0 0.3 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DOPA_dioxygen PF08883.11 KXZ43710.1 - 0.018 15.2 0.3 0.16 12.2 0.1 2.5 2 0 0 2 2 2 0 Dopa 4,5-dioxygenase family SHE3 PF17078.5 KXZ43710.1 - 0.025 14.3 9.9 0.053 13.2 9.8 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Parathyroid PF01279.17 KXZ43710.1 - 0.38 11.4 4.6 0.1 13.3 0.7 2.1 2 0 0 2 2 2 0 Parathyroid hormone family DUF410 PF04190.13 KXZ43711.1 - 1.7e-42 146.0 0.0 2.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) YjbE PF11106.8 KXZ43711.1 - 0.0063 16.7 0.3 0.0063 16.7 0.3 2.0 2 0 0 2 2 2 1 Exopolysaccharide production protein YjbE DUF2046 PF09755.9 KXZ43712.1 - 1.1e-39 136.5 51.6 1.7e-33 116.2 38.9 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) HALZ PF02183.18 KXZ43712.1 - 0.013 15.7 1.5 0.013 15.7 1.5 6.0 6 1 1 7 7 7 0 Homeobox associated leucine zipper SYCE1 PF15233.6 KXZ43712.1 - 0.024 14.7 11.9 0.024 14.7 11.9 3.9 1 1 2 4 4 4 0 Synaptonemal complex central element protein 1 ROK PF00480.20 KXZ43712.1 - 0.13 11.7 1.3 0.34 10.3 0.3 2.0 1 1 1 2 2 2 0 ROK family SHE3 PF17078.5 KXZ43712.1 - 1.4 8.6 35.1 3.1 7.5 19.7 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FAM184 PF15665.5 KXZ43712.1 - 2 8.1 42.7 1.7 8.4 27.3 2.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 KXZ43712.1 - 3.1 7.8 19.9 4.1 7.5 8.3 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HiaBD2 PF15403.6 KXZ43712.1 - 5.7 7.4 5.8 2.1 8.8 0.7 2.6 2 1 1 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Spc7 PF08317.11 KXZ43712.1 - 8.8 5.1 47.3 0.079 11.8 11.1 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein ICL PF00463.21 KXZ43714.1 - 3.2e-95 319.6 0.5 1.5e-47 162.3 0.0 2.2 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 KXZ43714.1 - 1.2e-18 67.5 0.2 4.4e-18 65.6 0.2 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF716 PF04819.12 KXZ43715.1 - 3.8e-16 59.0 6.6 8e-16 57.9 6.6 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF716) OAD_gamma PF04277.13 KXZ43715.1 - 4.7 7.9 5.6 8.6 7.0 2.7 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain UbiA PF01040.18 KXZ43716.1 - 7.7e-31 107.3 22.2 1.4e-30 106.5 22.2 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DBC1 PF14443.6 KXZ43716.1 - 7.1e-22 77.7 0.0 1.5e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 DBC1 EF-hand_6 PF13405.6 KXZ43716.1 - 0.046 13.7 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KXZ43718.1 - 0.0028 18.1 1.1 0.0059 17.0 0.4 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ43718.1 - 0.0043 16.9 0.7 0.2 11.6 0.0 2.9 3 1 1 4 4 4 1 EF-hand domain SurA_N_3 PF13624.6 KXZ43718.1 - 0.069 12.9 0.1 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_9 PF14658.6 KXZ43718.1 - 0.098 13.0 0.0 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KXZ43718.1 - 0.21 11.2 2.5 23 4.8 0.0 3.5 3 1 0 3 3 3 0 EF hand CENP-F_leu_zip PF10473.9 KXZ43719.1 - 0.0012 18.8 10.5 0.0012 18.8 10.5 12.3 6 1 6 14 14 14 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KXZ43719.1 - 0.018 15.1 0.0 0.018 15.1 0.0 11.8 7 3 5 13 13 13 0 Afadin- and alpha -actinin-Binding Cyclin_C_2 PF16899.5 KXZ43719.1 - 0.24 11.8 0.8 1.9 8.9 0.8 2.7 1 0 0 1 1 1 0 Cyclin C-terminal domain Spc42p PF11544.8 KXZ43719.1 - 0.44 10.6 5.0 0.61 10.1 0.0 3.8 4 0 0 4 4 4 0 Spindle pole body component Spc42p DUF1664 PF07889.12 KXZ43719.1 - 1.1 9.4 50.2 0.26 11.3 0.3 10.0 9 3 3 12 12 12 0 Protein of unknown function (DUF1664) BSD PF03909.17 KXZ43720.1 - 4.7e-13 48.9 0.5 1e-12 47.9 0.5 1.6 1 0 0 1 1 1 1 BSD domain CASP_C PF08172.12 KXZ43720.1 - 0.009 15.4 1.3 0.035 13.5 1.3 2.0 1 0 0 1 1 1 1 CASP C terminal ApoC-I PF04691.12 KXZ43720.1 - 0.049 13.6 0.4 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) TMF_TATA_bd PF12325.8 KXZ43720.1 - 0.86 9.8 8.3 1.1 9.4 0.1 3.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding YEATS PF03366.16 KXZ43721.1 - 3e-32 110.4 0.2 4.4e-32 109.9 0.2 1.3 1 0 0 1 1 1 1 YEATS family TRP PF06011.12 KXZ43722.1 - 2.3e-06 26.6 6.0 6e-06 25.2 6.0 1.6 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel EcsB PF05975.12 KXZ43722.1 - 0.011 14.6 0.0 0.011 14.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB NosD PF05048.13 KXZ43722.1 - 1.1 8.5 3.6 2.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Periplasmic copper-binding protein (NosD) Laminin_EGF PF00053.24 KXZ43722.1 - 7.5 6.8 7.3 3.1 8.0 3.6 2.3 2 0 0 2 2 2 0 Laminin EGF domain Chloroa_b-bind PF00504.21 KXZ43723.1 - 1.9e-51 174.8 0.0 2.5e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 KXZ43724.1 - 2.2e-78 262.3 0.3 1.3e-50 172.1 0.0 2.1 2 0 0 2 2 2 2 Chlorophyll A-B binding protein LMSTEN PF07988.12 KXZ43724.1 - 0.098 12.2 0.4 47 3.6 0.0 3.1 3 0 0 3 3 3 0 LMSTEN motif Chloroa_b-bind PF00504.21 KXZ43725.1 - 1.9e-51 174.8 0.0 2.4e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DNA_pol_phi PF04931.13 KXZ43726.1 - 5e-31 107.6 1.8 5e-31 107.6 1.8 3.8 3 1 0 3 3 3 2 DNA polymerase phi CCDC53 PF10152.9 KXZ43726.1 - 0.002 18.6 0.2 0.002 18.6 0.2 4.3 4 0 0 4 4 4 3 Subunit CCDC53 of WASH complex SPX PF03105.19 KXZ43726.1 - 2.4 8.0 22.1 1.9 8.3 5.4 2.6 3 0 0 3 3 3 0 SPX domain Ank_2 PF12796.7 KXZ43727.1 - 6.4e-08 33.1 6.0 0.015 15.9 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43727.1 - 0.0015 19.1 12.2 6.1 7.5 0.1 6.3 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43727.1 - 0.12 12.7 5.7 25 5.3 0.1 4.6 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Antimicrobial_1 PF08018.11 KXZ43727.1 - 4.6 7.5 8.6 2e+02 2.2 0.1 4.7 4 0 0 4 4 4 0 Frog antimicrobial peptide Chromo PF00385.24 KXZ43728.1 - 0.00025 20.9 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Adaptin_binding PF10199.9 KXZ43729.1 - 0.089 13.4 6.3 2.4 8.8 0.7 3.1 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 CAP PF00188.26 KXZ43730.1 - 3.3e-17 63.5 0.3 4e-17 63.2 0.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SRCR PF00530.18 KXZ43731.1 - 1.1e-17 64.4 1.6 2.6e-17 63.2 1.6 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain TRP PF06011.12 KXZ43731.1 - 8.1e-09 34.7 6.9 1.9e-08 33.5 6.9 1.6 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel CPP1-like PF11833.8 KXZ43731.1 - 0.89 9.2 5.1 12 5.5 5.5 2.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Laminin_EGF PF00053.24 KXZ43731.1 - 5.3 7.3 11.9 0.099 12.8 3.1 2.6 2 0 0 2 2 2 0 Laminin EGF domain SKG6 PF08693.10 KXZ43732.1 - 3.4 7.2 7.4 2.6 7.5 0.7 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF2252 PF10009.9 KXZ43733.1 - 1.9e-67 228.0 0.1 2.5e-67 227.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) GTP_EFTU PF00009.27 KXZ43734.1 - 6.3e-34 117.2 0.5 2.4e-32 112.0 0.5 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXZ43734.1 - 2.8e-27 94.9 0.2 9.5e-27 93.2 0.2 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 KXZ43734.1 - 2.9e-08 33.4 0.2 1.5e-07 31.1 0.2 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KXZ43734.1 - 2.7e-07 30.6 0.1 9.1e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KXZ43734.1 - 4.8e-05 23.0 0.1 0.00017 21.2 0.0 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KXZ43734.1 - 0.00099 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KXZ43734.1 - 0.0033 17.0 0.0 0.016 14.7 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KXZ43734.1 - 0.012 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 KXZ43734.1 - 0.019 15.4 0.6 9.3 6.7 0.0 3.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 PduV-EutP PF10662.9 KXZ43734.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation B3 PF02362.21 KXZ43735.1 - 2.4e-14 53.0 0.0 3.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 B3 DNA binding domain IBN_N PF03810.19 KXZ43736.1 - 6.3e-14 51.7 0.0 1.4e-12 47.3 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain BSP_II PF05432.11 KXZ43736.1 - 0.00046 20.0 8.6 0.00079 19.2 8.6 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) ParcG PF10274.9 KXZ43736.1 - 0.0017 18.5 0.0 0.085 13.0 0.0 2.4 1 1 1 2 2 2 1 Parkin co-regulated protein Xpo1 PF08389.12 KXZ43736.1 - 0.0028 17.7 0.0 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein RRN3 PF05327.11 KXZ43736.1 - 0.0062 15.1 0.3 0.012 14.2 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 HEAT_EZ PF13513.6 KXZ43736.1 - 0.016 15.7 7.2 13 6.4 0.0 5.5 6 0 0 6 6 5 0 HEAT-like repeat RTP1_C1 PF10363.9 KXZ43736.1 - 0.024 14.8 0.1 0.21 11.8 0.0 2.7 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF913 PF06025.12 KXZ43736.1 - 0.056 12.4 0.2 0.092 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CAS_CSE1 PF03378.15 KXZ43736.1 - 0.19 10.2 0.9 0.47 8.9 0.1 2.1 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus TFIIF_alpha PF05793.12 KXZ43736.1 - 0.24 10.0 15.4 0.37 9.3 15.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KXZ43736.1 - 0.32 9.1 11.8 0.54 8.4 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family HEAT PF02985.22 KXZ43736.1 - 0.42 11.0 2.8 52 4.5 0.0 4.9 5 0 0 5 5 4 0 HEAT repeat DUF2457 PF10446.9 KXZ43736.1 - 0.44 9.6 19.4 0.68 9.0 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KXZ43736.1 - 0.45 9.8 10.4 0.74 9.1 10.4 1.2 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 KXZ43736.1 - 0.66 9.7 3.5 71 3.1 6.2 2.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Pes-10 PF07149.11 KXZ43736.1 - 0.94 8.5 6.3 2.1 7.3 6.3 1.6 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 KXZ43736.1 - 0.96 8.7 10.3 2.2 7.5 10.3 1.5 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KXZ43736.1 - 0.97 9.1 6.5 3 7.5 6.5 1.9 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 KXZ43736.1 - 1.4 8.7 10.6 3.7 7.4 10.6 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region ABATE PF07336.11 KXZ43736.1 - 5.1 7.8 11.4 1.5 9.5 1.1 3.7 3 1 1 4 4 4 0 Putative stress-induced transcription regulator FYDLN_acid PF09538.10 KXZ43736.1 - 5.9 7.6 16.4 16 6.2 16.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) ER_lumen_recept PF00810.18 KXZ43737.1 - 4e-32 112.1 8.6 1.4e-25 90.9 5.3 2.4 2 0 0 2 2 2 2 ER lumen protein retaining receptor PQ-loop PF04193.14 KXZ43737.1 - 0.045 13.5 0.9 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 PQ loop repeat PAP2 PF01569.21 KXZ43737.1 - 5.4 6.8 14.1 0.16 11.7 1.2 3.3 2 1 0 2 2 2 0 PAP2 superfamily AIRS_C PF02769.22 KXZ43738.1 - 3e-27 95.7 0.3 4.4e-27 95.1 0.3 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KXZ43738.1 - 4e-20 72.3 0.7 1.1e-19 70.9 0.2 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain BTB PF00651.31 KXZ43739.1 - 3.9e-21 75.4 0.0 7.5e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain SBBP PF06739.11 KXZ43739.1 - 0.035 14.1 0.7 0.11 12.5 0.7 1.9 1 1 0 1 1 1 0 Beta-propeller repeat Ank_4 PF13637.6 KXZ43740.1 - 4e-12 46.4 10.1 0.069 13.8 0.1 9.4 7 3 3 10 10 10 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43740.1 - 2.5e-09 37.6 5.5 0.21 12.2 0.1 5.7 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43740.1 - 2.6e-05 24.2 12.4 7.9 7.4 0.0 9.2 10 1 1 11 11 11 1 Ankyrin repeat Ank_5 PF13857.6 KXZ43740.1 - 0.13 12.6 12.6 5.2 7.5 0.1 6.0 7 0 0 7 7 7 0 Ankyrin repeats (many copies) DUF1843 PF08898.10 KXZ43740.1 - 4.6 7.8 5.8 86 3.8 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 KXZ43741.1 - 6.8e-05 23.4 0.1 16 6.2 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43741.1 - 0.00024 21.6 2.0 39 5.0 0.0 5.9 4 1 2 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43741.1 - 0.029 14.7 5.0 43 4.6 0.0 4.6 4 1 1 5 5 5 0 Ankyrin repeats (many copies) ATX_III PF08098.11 KXZ43741.1 - 0.18 11.9 2.1 0.56 10.3 2.1 1.9 1 0 0 1 1 1 0 Anemonia sulcata toxin III family PfkB PF00294.24 KXZ43742.1 - 9.6e-45 153.2 0.9 7.9e-27 94.3 0.0 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Glyco_transf_4 PF13439.6 KXZ43742.1 - 0.077 13.0 0.1 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 RNase_HII PF01351.18 KXZ43743.1 - 7e-29 101.1 0.0 4.4e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease HII Pyr_redox_2 PF07992.14 KXZ43745.1 - 1.7e-10 40.6 0.2 6.4e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXZ43745.1 - 0.00033 20.8 0.0 0.0011 19.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXZ43745.1 - 0.00037 19.8 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXZ43745.1 - 0.00064 19.7 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KXZ43745.1 - 0.02 15.3 0.6 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Ank_2 PF12796.7 KXZ43747.1 - 1.5e-14 54.3 0.0 3.4e-12 46.8 0.0 3.7 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43747.1 - 5.9e-12 45.9 0.8 3.7e-07 30.6 0.0 4.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ43747.1 - 2.4e-11 43.7 0.6 1.6e-08 34.6 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43747.1 - 1.8e-09 37.1 0.5 0.032 14.7 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXZ43747.1 - 7.7e-07 29.3 4.3 0.063 13.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ion_trans PF00520.31 KXZ43747.1 - 0.0016 17.7 3.3 0.0022 17.3 3.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 KXZ43749.1 - 1.1e-10 41.9 9.1 0.27 11.9 0.0 8.9 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43749.1 - 1.6e-10 41.4 1.0 0.047 14.3 0.0 5.9 2 2 5 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43749.1 - 0.00026 21.2 14.4 1.1e+02 3.9 0.0 10.0 12 1 1 13 13 13 0 Ankyrin repeat HTH_15 PF12324.8 KXZ43749.1 - 0.0048 16.8 0.1 0.042 13.8 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase Ank_5 PF13857.6 KXZ43749.1 - 0.054 13.8 9.4 2.5 8.6 0.0 6.4 7 1 1 8 8 8 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43750.1 - 4.1e-11 43.3 4.0 0.012 16.2 0.0 4.6 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43750.1 - 2.7e-08 34.2 10.3 4 8.1 0.0 9.4 5 3 4 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43750.1 - 0.12 13.0 14.8 61 4.7 0.0 9.2 13 1 1 14 14 14 0 Ankyrin repeat ATX_III PF08098.11 KXZ43750.1 - 4.4 7.4 6.9 29 4.8 0.9 3.7 3 0 0 3 3 3 0 Anemonia sulcata toxin III family Beta_helix PF13229.6 KXZ43751.1 - 2.7e-16 59.8 1.1 1.4e-15 57.5 0.0 2.7 2 1 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 KXZ43751.1 - 1.3e-06 27.9 1.6 0.0057 15.9 0.0 3.5 3 1 0 4 4 4 3 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KXZ43751.1 - 0.00073 19.0 0.5 1.3 8.3 0.2 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF1565) AAA PF00004.29 KXZ43752.1 - 6.2e-06 26.7 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ43752.1 - 0.00019 21.9 0.0 0.00049 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KXZ43752.1 - 0.00057 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ43752.1 - 0.00088 19.6 0.1 0.0039 17.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXZ43752.1 - 0.0029 17.6 0.1 0.0079 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXZ43752.1 - 0.0044 17.0 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KXZ43752.1 - 0.005 16.8 0.1 0.058 13.3 0.1 2.1 1 1 1 2 2 2 1 NTPase AAA_29 PF13555.6 KXZ43752.1 - 0.014 15.2 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXZ43752.1 - 0.014 14.9 0.7 0.083 12.4 0.2 2.3 1 1 0 2 2 2 0 AAA domain cobW PF02492.19 KXZ43752.1 - 0.015 14.9 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXZ43752.1 - 0.019 14.0 0.1 0.037 13.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KXZ43752.1 - 0.019 15.5 0.1 0.087 13.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 KXZ43752.1 - 0.03 14.1 0.0 0.051 13.3 0.0 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 KXZ43752.1 - 0.048 13.7 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 KXZ43752.1 - 0.061 13.4 0.1 0.09 12.9 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 KXZ43752.1 - 0.063 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXZ43752.1 - 0.082 13.2 0.0 0.23 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KXZ43752.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain LytR_C PF13399.6 KXZ43752.1 - 0.13 13.3 0.1 39 5.3 0.0 3.1 1 1 1 2 2 2 0 LytR cell envelope-related transcriptional attenuator AAA_28 PF13521.6 KXZ43752.1 - 0.14 12.4 0.0 0.94 9.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain KdpD PF02702.17 KXZ43752.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain G-alpha PF00503.20 KXZ43752.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 KXZ43752.1 - 0.27 10.9 0.0 0.44 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ank_4 PF13637.6 KXZ43754.1 - 0.003 18.1 0.1 16 6.2 0.0 4.6 4 2 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43754.1 - 0.089 13.4 0.1 5.4 7.7 0.0 2.9 2 1 0 3 3 3 0 Ankyrin repeats (3 copies) AAA PF00004.29 KXZ43755.1 - 9.4e-06 26.1 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ43755.1 - 0.00025 21.5 1.5 0.00031 21.2 0.1 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_30 PF13604.6 KXZ43755.1 - 0.00069 19.4 0.1 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ43755.1 - 0.001 19.4 0.1 0.004 17.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXZ43755.1 - 0.0049 16.9 0.1 0.012 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXZ43755.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KXZ43755.1 - 0.0086 16.0 0.1 0.091 12.7 0.1 2.1 1 1 1 2 2 2 1 NTPase AAA_25 PF13481.6 KXZ43755.1 - 0.012 15.2 1.0 0.095 12.3 0.1 2.8 2 1 0 3 3 3 0 AAA domain MeaB PF03308.16 KXZ43755.1 - 0.022 13.8 0.1 0.041 12.9 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KXZ43755.1 - 0.022 14.4 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KXZ43755.1 - 0.035 14.6 0.1 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 KXZ43755.1 - 0.037 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KXZ43755.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KXZ43755.1 - 0.046 13.5 0.0 0.076 12.7 0.0 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.20 KXZ43755.1 - 0.068 12.3 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit CbiA PF01656.23 KXZ43755.1 - 0.072 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KXZ43755.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KXZ43755.1 - 0.091 12.8 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_19 PF13245.6 KXZ43755.1 - 0.1 12.9 0.1 0.25 11.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KXZ43755.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ43755.1 - 0.22 11.5 0.0 0.52 10.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ank_2 PF12796.7 KXZ43756.1 - 6.2e-05 23.5 0.1 0.32 11.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43756.1 - 7.2e-05 23.3 3.8 0.61 10.7 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43756.1 - 0.00022 21.4 1.6 5.6 7.9 0.0 5.6 5 1 1 6 6 6 1 Ankyrin repeat PHY PF00360.20 KXZ43756.1 - 0.0095 15.3 0.2 0.02 14.2 0.1 1.6 1 1 0 1 1 1 1 Phytochrome region Ank_5 PF13857.6 KXZ43756.1 - 0.038 14.3 6.1 0.62 10.4 0.1 4.7 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ43757.1 - 6.6e-07 29.8 0.5 0.13 12.8 0.0 4.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43757.1 - 6.4e-06 26.7 0.1 0.074 13.6 0.0 3.6 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43757.1 - 0.00051 20.3 2.6 1.7e+02 3.3 0.0 6.3 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 KXZ43757.1 - 0.09 13.1 0.3 8.1 6.9 0.0 3.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) PLAC8 PF04749.17 KXZ43758.1 - 4e-13 50.2 11.5 6.6e-13 49.5 11.5 1.3 1 0 0 1 1 1 1 PLAC8 family Ank_2 PF12796.7 KXZ43759.1 - 3.7e-09 37.0 0.1 0.98 10.1 0.0 4.7 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ43759.1 - 2.6e-08 34.2 0.7 6 7.6 0.0 6.6 5 3 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ43759.1 - 2.4e-05 24.3 7.7 25 5.8 0.0 8.2 9 1 1 10 10 10 1 Ankyrin repeat Ank_5 PF13857.6 KXZ43759.1 - 0.0023 18.2 2.3 17 5.9 0.1 5.5 4 2 2 6 6 6 1 Ankyrin repeats (many copies) PDEase_I_N PF08499.12 KXZ43759.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF4806 PF16064.5 KXZ43760.1 - 0.22 11.8 0.0 0.3 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) GST_N_3 PF13417.6 KXZ43763.1 - 7.3e-14 51.9 0.0 1.5e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXZ43763.1 - 6.7e-09 36.0 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXZ43763.1 - 1.7e-07 31.4 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ43763.1 - 6.6e-05 22.9 0.3 0.00017 21.5 0.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TetR_C_15 PF17918.1 KXZ43763.1 - 0.14 13.0 4.3 0.32 11.8 1.5 2.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CytB6-F_Fe-S PF08802.10 KXZ43764.1 - 4.4e-11 42.6 0.6 4.4e-11 42.6 0.6 2.2 2 1 1 3 3 3 1 Cytochrome B6-F complex Fe-S subunit Rieske PF00355.26 KXZ43764.1 - 0.05 13.5 0.1 0.62 10.0 0.1 2.2 1 1 0 1 1 1 0 Rieske [2Fe-2S] domain YchF-GTPase_C PF06071.13 KXZ43765.1 - 3.9e-35 119.9 0.8 6.3e-35 119.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXZ43765.1 - 1.5e-22 79.9 0.0 2.2e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ43765.1 - 3e-07 30.1 0.1 4.5e-07 29.5 0.1 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KXZ43765.1 - 0.036 13.1 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Serglycin PF04360.12 KXZ43766.1 - 0.54 10.2 5.0 0.94 9.4 5.0 1.3 1 0 0 1 1 1 0 Serglycin BTB PF00651.31 KXZ43768.1 - 1.4e-17 63.9 0.0 2.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ43769.1 - 2.9e-18 66.1 0.0 4.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Linker_histone PF00538.19 KXZ43771.1 - 2.3e-17 63.1 3.6 1.5e-15 57.3 0.1 2.5 2 0 0 2 2 2 2 linker histone H1 and H5 family ColG_sub PF18496.1 KXZ43771.1 - 0.0079 16.3 1.4 3.4 7.8 0.1 2.2 1 1 1 2 2 2 2 Collagenase G catalytic helper subdomain ANAPC2 PF08672.11 KXZ43771.1 - 0.062 13.8 0.5 17 6.0 0.1 2.2 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Erythrovirus_X PF06795.11 KXZ43771.1 - 0.28 11.5 2.8 18 5.7 0.2 2.3 2 0 0 2 2 2 0 Erythrovirus X protein Cauli_VI PF01693.16 KXZ43772.1 - 4.3e-08 33.3 1.6 5.5e-07 29.8 1.6 2.3 2 0 0 2 2 2 1 Caulimovirus viroplasmin RVT_3 PF13456.6 KXZ43773.1 - 2.5e-05 24.1 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like C2 PF00168.30 KXZ43774.1 - 0.0002 21.6 0.0 0.00031 21.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain SR-25 PF10500.9 KXZ43775.1 - 0.45 10.1 5.6 0.75 9.4 5.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YqfQ PF14181.6 KXZ43776.1 - 0.71 10.0 12.4 2.6 8.2 1.0 2.5 1 1 1 2 2 2 0 YqfQ-like protein RunxI PF08504.11 KXZ43779.1 - 0.13 13.0 0.0 0.19 12.4 0.0 1.3 1 0 0 1 1 1 0 Runx inhibition domain GRAM PF02893.20 KXZ43779.1 - 0.13 12.1 0.1 0.33 10.9 0.1 1.6 1 1 0 1 1 1 0 GRAM domain G8 PF10162.9 KXZ43781.1 - 7.6e-10 38.9 0.0 2.2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 G8 domain CBM_4_9 PF02018.17 KXZ43781.1 - 0.00066 20.0 0.3 0.016 15.5 0.2 2.8 2 0 0 2 2 2 1 Carbohydrate binding domain Beta_helix PF13229.6 KXZ43781.1 - 0.29 11.0 4.7 2.3 8.1 1.1 2.4 2 0 0 2 2 2 0 Right handed beta helix region ShK PF01549.24 KXZ43781.1 - 6.5 7.4 21.3 3.9 8.1 0.5 4.6 4 0 0 4 4 4 0 ShK domain-like Piwi PF02171.17 KXZ43782.1 - 9.6e-73 245.0 0.0 4e-41 141.2 0.0 2.1 1 1 1 2 2 2 2 Piwi domain ArgoN PF16486.5 KXZ43782.1 - 3.3e-07 31.0 0.0 8.6e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXZ43782.1 - 0.00011 21.8 0.5 0.00027 20.6 0.5 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KXZ43782.1 - 0.0029 17.8 0.1 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 Mid domain of argonaute BAR PF03114.18 KXZ43783.1 - 2.6e-08 33.8 7.0 2.6e-08 33.8 7.0 1.8 2 1 0 2 2 2 1 BAR domain Allexi_40kDa PF05549.11 KXZ43783.1 - 0.016 14.7 1.2 0.54 9.7 0.9 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein FapA PF03961.13 KXZ43783.1 - 0.02 13.5 2.0 0.034 12.8 2.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 KXZ43783.1 - 0.041 14.2 9.3 0.041 14.2 3.0 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) PIN_8 PF18476.1 KXZ43783.1 - 0.061 13.2 1.6 0.36 10.7 0.6 2.1 2 0 0 2 2 2 0 PIN like domain APG6_N PF17675.1 KXZ43783.1 - 0.074 13.6 13.1 0.18 12.3 10.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4657 PF15552.6 KXZ43783.1 - 0.089 12.3 3.6 0.2 11.2 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) Acyl-CoA_ox_N PF14749.6 KXZ43783.1 - 0.14 12.7 3.3 0.35 11.4 1.6 2.2 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Atg14 PF10186.9 KXZ43783.1 - 0.2 10.7 9.2 0.69 8.9 9.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 KXZ43783.1 - 0.34 10.9 8.6 0.38 10.8 6.9 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding T3SSipB PF16535.5 KXZ43783.1 - 0.39 11.2 5.0 0.079 13.4 1.2 1.7 2 0 0 2 2 1 0 Type III cell invasion protein SipB DUF2203 PF09969.9 KXZ43783.1 - 0.5 11.1 6.9 0.58 10.9 2.8 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2203) DegT_DnrJ_EryC1 PF01041.17 KXZ43783.1 - 0.56 9.5 3.3 1.7 7.9 2.4 2.2 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4192 PF13830.6 KXZ43783.1 - 0.74 9.8 7.0 1.9 8.5 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Ax_dynein_light PF10211.9 KXZ43783.1 - 1.3 8.9 9.9 0.18 11.8 4.7 2.2 3 0 0 3 3 3 0 Axonemal dynein light chain DUF1664 PF07889.12 KXZ43783.1 - 1.6 8.8 5.5 1.4 8.9 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KXZ43783.1 - 1.6 8.9 18.2 0.29 11.3 1.0 3.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 KXZ43783.1 - 2.6 8.4 6.2 3.3 8.1 0.1 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.12 KXZ43783.1 - 2.9 8.3 9.3 1.3 9.4 3.4 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Cnn_1N PF07989.11 KXZ43783.1 - 4.9 7.4 14.1 2.4 8.4 0.1 3.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Exonuc_VII_L PF02601.15 KXZ43783.1 - 6.1 6.3 8.8 11 5.4 8.8 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 KXZ43783.1 - 7.9 4.9 11.6 4.6 5.6 0.2 2.4 1 1 0 2 2 2 0 Fusaric acid resistance protein family Guanylate_cyc PF00211.20 KXZ43787.1 - 2.9e-55 186.7 0.0 4.7e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 KXZ43787.1 - 0.011 16.0 0.1 4.1 7.7 0.0 3.3 3 0 0 3 3 3 0 PAS fold PAS_8 PF13188.7 KXZ43787.1 - 0.021 14.8 0.0 7.2 6.8 0.0 2.9 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 KXZ43787.1 - 0.1 12.6 0.0 33 4.5 0.0 3.0 3 0 0 3 3 3 0 PAS fold Guanylate_cyc PF00211.20 KXZ43788.1 - 4e-37 127.6 0.1 1.2e-24 86.9 0.0 2.2 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 KXZ43789.1 - 0.00088 19.5 0.0 0.66 10.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KXZ43789.1 - 0.0031 17.5 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KXZ43789.1 - 0.01 15.8 0.0 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 PAS fold Guanylate_cyc PF00211.20 KXZ43790.1 - 3e-56 190.0 0.0 4.4e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Dimer_Tnp_hAT PF05699.14 KXZ43791.1 - 2.3e-09 36.9 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FliS PF02561.14 KXZ43792.1 - 0.06 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FliS PAS_4 PF08448.10 KXZ43794.1 - 0.0022 18.2 0.2 2.8 8.2 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 KXZ43794.1 - 0.0061 16.6 0.0 4.6 7.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KXZ43794.1 - 0.017 15.1 0.0 7.7 6.5 0.0 2.4 2 0 0 2 2 2 0 PAS fold Guanylate_cyc PF00211.20 KXZ43795.1 - 2.8e-56 190.0 0.0 4.3e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CbiD PF01888.17 KXZ43795.1 - 0.15 11.3 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 CbiD EamA PF00892.20 KXZ43797.1 - 1.6e-05 25.1 5.4 2.5e-05 24.5 2.4 2.5 1 1 1 2 2 2 1 EamA-like transporter family Nuc_sug_transp PF04142.15 KXZ43797.1 - 0.00043 19.6 0.2 0.00058 19.1 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 KXZ43797.1 - 0.00073 18.9 0.1 0.00094 18.5 0.1 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport MCR_beta PF02241.18 KXZ43797.1 - 0.02 14.5 0.4 0.036 13.7 0.2 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain PGC7_Stella PF15549.6 KXZ43798.1 - 0.013 15.5 3.4 0.025 14.6 3.4 1.4 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain U3_snoRNA_assoc PF08297.11 KXZ43798.1 - 1 10.1 13.5 0.94 10.2 0.6 2.4 2 0 0 2 2 2 0 U3 snoRNA associated VIR_N PF15912.5 KXZ43798.1 - 4 7.0 10.7 7 6.2 10.7 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal rRNA_processing PF08524.11 KXZ43798.1 - 6.2 6.8 15.9 3.2 7.8 11.5 2.0 2 0 0 2 2 2 0 rRNA processing Rrn6 PF10214.9 KXZ43798.1 - 8 4.8 11.4 1.2 7.6 6.9 1.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Reticulon PF02453.17 KXZ43799.1 - 1.4e-18 67.3 1.9 1.4e-18 67.3 1.9 2.0 3 0 0 3 3 3 1 Reticulon PDR_assoc PF08370.11 KXZ43799.1 - 0.094 12.5 1.9 0.21 11.4 1.9 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Anoctamin PF04547.12 KXZ43799.1 - 0.22 10.3 0.7 0.37 9.6 0.0 1.6 2 0 0 2 2 2 0 Calcium-activated chloride channel KASH_CCD PF14662.6 KXZ43799.1 - 0.54 10.0 8.3 0.89 9.4 8.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF1640 PF07798.11 KXZ43799.1 - 0.55 10.3 4.7 1 9.4 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF724 PF05266.14 KXZ43799.1 - 1.2 9.0 4.6 2.3 8.0 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LRR_4 PF12799.7 KXZ43800.1 - 0.0088 16.4 1.4 2.7 8.5 0.2 4.7 4 2 3 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ43800.1 - 0.026 15.0 4.0 9.2 7.3 0.2 4.9 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KXZ43800.1 - 0.058 13.5 0.2 11 6.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat GNAT_like PF18407.1 KXZ43800.1 - 3.6 8.0 12.4 0.16 12.4 2.0 2.9 3 0 0 3 3 3 0 GCN5-related N-acetyltransferase like domain zf-MYND PF01753.18 KXZ43802.1 - 6.6e-06 26.1 7.5 1.3e-05 25.2 7.5 1.5 1 0 0 1 1 1 1 MYND finger Mfa1 PF17445.2 KXZ43804.1 - 0.017 15.1 1.6 0.029 14.4 1.6 1.4 1 0 0 1 1 1 0 Mating factor A1 FSA_C PF10479.9 KXZ43805.1 - 8.2 4.4 7.1 11 3.9 7.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FF PF01846.19 KXZ43807.1 - 1.2e-23 83.1 0.0 5.7e-08 32.8 0.0 3.4 3 0 0 3 3 3 3 FF domain Pkinase PF00069.25 KXZ43807.1 - 1.2e-15 57.7 0.0 6.1e-15 55.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43807.1 - 2.8e-05 23.5 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ43807.1 - 0.005 16.2 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1640 PF07798.11 KXZ43807.1 - 0.072 13.1 0.5 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) SlyX PF04102.12 KXZ43807.1 - 0.15 12.7 1.7 0.55 10.9 1.7 2.0 1 0 0 1 1 1 0 SlyX JIP_LZII PF16471.5 KXZ43807.1 - 0.18 12.0 2.7 0.35 11.1 2.7 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II TolA_bind_tri PF16331.5 KXZ43807.1 - 0.47 10.6 4.1 1.2 9.3 4.1 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation DNase-RNase PF02577.14 KXZ43808.1 - 7.8e-34 116.1 0.2 1.4e-33 115.3 0.2 1.4 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 KXZ43808.1 - 2.6e-05 23.8 6.2 0.0037 16.9 0.9 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif DUF4157 PF13699.6 KXZ43808.1 - 0.075 13.3 0.2 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Sporozoite_P67 PF05642.11 KXZ43809.1 - 0.095 10.8 5.3 1.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.14 KXZ43809.1 - 0.22 11.3 4.7 3.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2201_N PF13203.6 KXZ43809.1 - 0.27 10.8 2.7 0.79 9.3 2.7 1.8 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.12 KXZ43809.1 - 0.45 8.7 13.3 0.74 8.0 1.4 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KXZ43809.1 - 0.64 9.3 11.5 2.3 7.5 1.6 2.2 2 0 0 2 2 2 0 BUD22 Sigma70_ner PF04546.13 KXZ43809.1 - 0.7 9.7 17.2 1.6 8.6 5.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.12 KXZ43809.1 - 0.81 9.1 14.4 1.3 8.4 3.2 2.2 2 0 0 2 2 2 0 SDA1 BSP_II PF05432.11 KXZ43809.1 - 2.2 7.9 16.0 0.8 9.3 4.4 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 KXZ43809.1 - 4.4 7.0 11.8 9.1 5.9 1.0 2.3 2 0 0 2 2 2 0 FAM176 family TFB6 PF17110.5 KXZ43809.1 - 7.9 6.2 5.6 7.9 6.2 0.4 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Bep_C_terminal PF17841.1 KXZ43809.1 - 8.7 6.6 6.8 1.9 8.7 0.1 2.9 3 0 0 3 3 3 0 BID domain of Bartonella effector protein (Bep) IF-2B PF01008.17 KXZ43811.1 - 1.8e-71 240.7 0.0 2.2e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Raf1_N PF18578.1 KXZ43811.1 - 0.013 16.0 0.5 0.024 15.1 0.5 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain FeThRed_A PF02941.15 KXZ43812.1 - 1.9e-23 82.4 1.2 3.4e-23 81.6 0.3 2.0 2 0 0 2 2 2 1 Ferredoxin thioredoxin reductase variable alpha chain Baculo_PEP_C PF04513.12 KXZ43812.1 - 0.00041 20.4 30.5 0.14 12.2 1.7 7.7 4 3 3 7 7 7 4 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KXZ43812.1 - 0.0013 18.8 39.9 0.25 11.4 2.4 7.9 6 3 3 9 9 9 4 Protein of unknown function (DUF1664) DinI PF06183.13 KXZ43812.1 - 0.013 15.8 0.9 2.8 8.3 0.0 4.0 3 0 0 3 3 3 0 DinI-like family MHB PF16525.5 KXZ43812.1 - 0.048 13.9 8.3 0.53 10.6 0.2 4.3 4 1 0 4 4 4 0 Haemophore, haem-binding Med26 PF08711.11 KXZ43812.1 - 0.056 13.5 0.1 0.34 11.0 0.0 2.4 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Prominin PF05478.11 KXZ43812.1 - 0.66 7.9 19.8 0.057 11.4 1.2 2.9 3 0 0 3 3 3 0 Prominin Fzo_mitofusin PF04799.13 KXZ43812.1 - 3.6 7.1 23.3 0.43 10.1 0.2 5.9 3 2 1 6 6 6 0 fzo-like conserved region CorA PF01544.18 KXZ43812.1 - 6.1 6.1 25.4 0.78 9.0 1.1 5.0 4 1 1 5 5 5 0 CorA-like Mg2+ transporter protein Arm PF00514.23 KXZ43813.1 - 8.9e-06 25.6 4.3 0.054 13.6 0.3 4.1 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KXZ43813.1 - 0.0084 16.1 0.3 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain MatC_N PF07158.11 KXZ43813.1 - 0.14 12.2 0.7 0.36 10.9 0.7 1.6 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus HEAT_EZ PF13513.6 KXZ43813.1 - 0.68 10.5 4.9 0.85 10.2 1.1 3.1 2 1 1 3 3 3 0 HEAT-like repeat WD40 PF00400.32 KXZ43814.1 - 6.4e-07 30.0 9.6 0.016 16.0 0.0 4.8 4 1 1 5 5 5 3 WD domain, G-beta repeat MMS1_N PF10433.9 KXZ43815.1 - 3.2e-09 36.0 0.0 6.1e-09 35.0 0.0 1.4 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term SET PF00856.28 KXZ43815.1 - 2.4e-08 34.6 0.0 1.2e-07 32.3 0.0 2.0 1 1 0 1 1 1 1 SET domain CPSF_A PF03178.15 KXZ43816.1 - 2.2e-38 132.4 0.0 7e-38 130.7 0.0 1.6 1 1 0 1 1 1 1 CPSF A subunit region UK PF02512.14 KXZ43816.1 - 0.15 12.6 0.0 7.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Virulence determinant Metallophos PF00149.28 KXZ43817.1 - 0.047 14.2 0.5 0.37 11.2 0.1 2.5 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase AAA_12 PF13087.6 KXZ43818.1 - 2.2e-46 158.0 0.0 5.6e-46 156.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ43818.1 - 4.2e-17 62.8 0.0 5.9e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ43818.1 - 5.5e-06 26.3 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KXZ43818.1 - 0.00033 20.4 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ43818.1 - 0.0013 19.0 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXZ43818.1 - 0.0045 16.8 0.1 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXZ43819.1 - 4.2e-08 33.1 0.0 1.6e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KXZ43819.1 - 3.4e-06 27.5 0.0 0.01 16.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 KXZ43819.1 - 0.00064 19.5 0.0 1 9.2 0.0 3.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KXZ43819.1 - 0.069 13.4 0.0 4.2 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXZ43819.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C PF13361.6 KXZ43819.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain p450 PF00067.22 KXZ43820.1 - 2.6e-65 221.0 0.0 6.9e-58 196.5 0.0 3.8 3 1 1 4 4 4 3 Cytochrome P450 Vps8 PF12816.7 KXZ43821.1 - 1.7e-19 70.1 0.0 8.1e-19 67.9 0.0 2.1 1 1 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KXZ43821.1 - 6.2e-09 35.9 0.0 5.9e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_7 PF13176.6 KXZ43821.1 - 0.21 11.7 1.0 5.5 7.3 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KXZ43823.1 - 2.3e-30 105.9 0.0 1.8e-13 50.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43823.1 - 1.4e-24 86.8 0.0 1e-10 41.3 0.0 3.8 3 2 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43823.1 - 0.065 12.0 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase BTB PF00651.31 KXZ43827.1 - 0.0001 22.5 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain PGA_cap PF09587.10 KXZ43828.1 - 5.2e-40 137.5 0.0 9.4e-26 90.8 0.0 2.1 1 1 1 2 2 2 2 Bacterial capsule synthesis protein PGA_cap DUF3678 PF12435.8 KXZ43829.1 - 0.0095 15.3 0.2 0.021 14.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3678) DUF1993 PF09351.10 KXZ43829.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Methyltr_RsmB-F PF01189.17 KXZ43830.1 - 2.3e-19 69.8 0.0 4e-19 69.0 0.0 1.3 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Collagen PF01391.18 KXZ43830.1 - 0.032 14.0 18.1 0.052 13.3 18.1 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Methyltr_RsmB-F PF01189.17 KXZ43831.1 - 1e-09 38.3 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 KXZ43831.1 - 8.6e-08 32.0 0.5 1.4e-05 25.0 0.2 2.3 2 0 0 2 2 2 2 PUA domain Methyltr_RsmF_N PF17125.5 KXZ43831.1 - 0.08 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KXZ43831.1 - 0.094 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase CDC45 PF02724.14 KXZ43832.1 - 1.1 7.5 14.6 1.6 6.9 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 KXZ43832.1 - 2.7 8.0 22.4 5.9 6.9 22.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 tRNA-synt_1b PF00579.25 KXZ43833.1 - 1.9e-72 244.0 0.0 2.9e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 KXZ43833.1 - 2.5e-10 39.9 0.0 6.2e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 KXZ43833.1 - 0.22 11.4 0.9 2 8.2 0.1 2.2 1 1 1 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain EFG_C PF00679.24 KXZ43834.1 - 3.9e-07 30.0 0.1 0.00016 21.7 0.0 2.7 3 0 0 3 3 3 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXZ43834.1 - 1.4e-06 28.6 1.5 1.4e-06 28.6 1.5 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 p450 PF00067.22 KXZ43836.1 - 1.7e-44 152.4 0.0 2.2e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TelA PF05816.11 KXZ43836.1 - 0.0044 16.1 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) LisH PF08513.11 KXZ43838.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 LisH PrmA PF06325.13 KXZ43839.1 - 0.00011 21.8 0.4 0.00016 21.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXZ43839.1 - 0.0043 16.8 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KXZ43839.1 - 0.0054 17.4 0.1 0.019 15.6 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ43839.1 - 0.043 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXZ43839.1 - 0.092 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Biotin_carb_N PF00289.22 KXZ43840.1 - 9.9e-25 87.2 0.0 1.5e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CPSase_L_D2 PF02786.17 KXZ43840.1 - 1.8e-23 83.1 0.0 2.7e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 KXZ43840.1 - 0.0031 17.1 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXZ43840.1 - 0.004 16.7 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus KDGP_aldolase PF07071.11 KXZ43840.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 KDGP aldolase ATP-grasp_3 PF02655.14 KXZ43840.1 - 0.15 12.1 0.0 0.93 9.5 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Carboxyl_trans PF01039.22 KXZ43841.1 - 1.5e-54 185.4 0.0 2.2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain PRIMA1 PF16101.5 KXZ43841.1 - 0.21 11.6 5.2 0.33 11.0 5.2 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Proteasome PF00227.26 KXZ43842.1 - 3.1e-61 206.2 0.2 4.2e-61 205.7 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXZ43842.1 - 1.4e-10 40.6 0.7 2.5e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PsbQ PF05757.11 KXZ43843.1 - 6.6e-54 182.7 9.8 8.5e-54 182.3 9.8 1.0 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) IKI3 PF04762.12 KXZ43844.1 - 5.2e-139 464.9 0.0 1.2e-60 205.6 0.0 3.3 2 1 0 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 KXZ43844.1 - 0.00037 20.7 0.0 0.023 15.0 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KXZ43844.1 - 0.087 12.7 0.3 7 6.5 0.0 3.0 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Pkinase PF00069.25 KXZ43845.1 - 9.4e-69 231.7 0.0 1.1e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43845.1 - 6.3e-27 94.5 0.0 1.1e-26 93.8 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXZ43845.1 - 0.002 18.1 1.3 0.071 13.0 0.3 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ43845.1 - 0.031 13.2 0.1 0.068 12.1 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KXZ43845.1 - 0.047 13.0 0.1 0.4 10.0 0.0 2.2 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 KXZ43845.1 - 0.093 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KXZ43845.1 - 0.23 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MMS1_N PF10433.9 KXZ43846.1 - 5.6e-160 533.2 0.0 8.3e-160 532.6 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXZ43846.1 - 8.1e-87 291.5 0.0 2.1e-86 290.2 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region LYTB PF02401.18 KXZ43848.1 - 1.3e-81 273.8 0.2 1.5e-81 273.5 0.2 1.1 1 0 0 1 1 1 1 LytB protein LRR_8 PF13855.6 KXZ43849.1 - 2.5e-21 75.2 46.5 3.1e-10 39.6 9.8 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KXZ43849.1 - 1.1e-19 70.2 19.4 6.8e-08 32.7 4.0 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXZ43849.1 - 3.9e-10 39.5 3.8 0.00016 21.2 0.9 2.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KXZ43849.1 - 0.24 12.1 17.2 10 7.1 0.1 5.9 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KXZ43849.1 - 0.59 10.3 21.5 6.3 7.1 0.2 5.4 6 0 0 6 6 6 0 Leucine Rich repeat Golgin_A5 PF09787.9 KXZ43849.1 - 7.4 5.9 95.6 0.091 12.2 7.4 6.2 1 1 5 6 6 6 0 Golgin subfamily A member 5 Pkinase PF00069.25 KXZ43850.1 - 4e-47 160.8 0.0 1.9e-46 158.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43850.1 - 1.4e-45 155.6 0.0 2.1e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UQ_con PF00179.26 KXZ43850.1 - 4.5e-10 39.3 0.0 8.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APH PF01636.23 KXZ43850.1 - 0.0046 16.9 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ43850.1 - 0.13 11.0 0.0 0.3 9.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase DUF2868 PF11067.8 KXZ43850.1 - 0.19 11.2 3.0 0.33 10.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Prok-E2_B PF14461.6 KXZ43850.1 - 0.2 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B MSA-2c PF12238.8 KXZ43850.1 - 1.3 9.0 4.2 2.8 7.9 4.2 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF1180 PF06679.12 KXZ43850.1 - 7.5 6.9 9.4 0.33 11.3 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EamA PF00892.20 KXZ43851.1 - 2e-18 66.9 27.0 1.1e-10 41.8 12.7 4.0 3 1 1 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.15 KXZ43851.1 - 1e-05 24.9 0.3 9.1e-05 21.8 0.2 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter ABC_tran PF00005.27 KXZ43852.1 - 1.9e-54 183.9 4.7 4.5e-27 95.2 0.1 3.4 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KXZ43852.1 - 5.2e-18 64.9 2.4 5.2e-18 64.9 2.4 3.4 3 1 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KXZ43852.1 - 1.8e-13 51.0 3.5 0.0006 19.7 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ43852.1 - 2.8e-09 36.8 3.1 0.071 12.5 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXZ43852.1 - 3.9e-07 30.1 0.0 0.0008 19.2 0.0 3.3 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KXZ43852.1 - 9.1e-07 28.5 0.2 0.0019 17.9 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXZ43852.1 - 1.1e-06 28.9 1.2 0.0012 19.1 0.0 3.3 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXZ43852.1 - 5.5e-06 26.4 0.3 0.0012 18.9 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXZ43852.1 - 9.2e-06 25.9 0.0 0.036 14.2 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KXZ43852.1 - 1.1e-05 25.3 0.5 0.028 14.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXZ43852.1 - 1.4e-05 25.6 0.3 0.022 15.1 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXZ43852.1 - 1.9e-05 24.6 2.7 0.0071 16.3 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXZ43852.1 - 0.00015 21.9 0.0 0.037 14.1 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KXZ43852.1 - 0.00072 19.5 0.4 0.53 10.2 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA_18 PF13238.6 KXZ43852.1 - 0.0017 18.9 0.2 1.6 9.3 0.0 3.3 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 KXZ43852.1 - 0.0032 16.5 0.3 0.31 10.0 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KXZ43852.1 - 0.0032 17.1 0.0 2.6 7.6 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KXZ43852.1 - 0.0047 17.4 0.0 0.0047 17.4 0.0 4.3 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXZ43852.1 - 0.0072 16.1 2.2 0.94 9.2 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA PF00004.29 KXZ43852.1 - 0.008 16.6 0.2 9.2 6.7 0.3 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KXZ43852.1 - 0.01 15.9 6.6 1.8 8.6 0.2 3.5 3 1 0 3 3 3 0 Dynamin family AAA_28 PF13521.6 KXZ43852.1 - 0.014 15.7 0.0 0.27 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXZ43852.1 - 0.019 14.9 0.0 7.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXZ43852.1 - 0.022 14.8 2.2 2.5 8.1 0.0 3.8 3 2 2 5 5 5 0 AAA domain NTPase_1 PF03266.15 KXZ43852.1 - 0.024 14.6 1.2 13 5.7 0.0 4.2 4 0 0 4 4 4 0 NTPase AAA_7 PF12775.7 KXZ43852.1 - 0.024 14.1 0.0 8.1 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_27 PF13514.6 KXZ43852.1 - 0.031 13.9 1.6 0.37 10.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 KXZ43852.1 - 0.035 13.8 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KXZ43852.1 - 0.036 14.3 0.0 3 8.1 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 KXZ43852.1 - 0.038 13.7 0.5 8.4 6.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Thymidylate_kin PF02223.17 KXZ43852.1 - 0.049 13.3 8.8 0.059 13.0 0.0 3.7 4 0 0 4 4 4 0 Thymidylate kinase AAA_25 PF13481.6 KXZ43852.1 - 0.057 13.0 0.1 7.6 6.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain Saccharop_dh_N PF04455.12 KXZ43852.1 - 1.2 9.6 3.8 0.83 10.1 0.2 2.6 3 1 1 4 4 1 0 LOR/SDH bifunctional enzyme conserved region Tup_N PF08581.10 KXZ43852.1 - 2.7 8.4 11.8 0.042 14.1 1.6 2.5 2 0 0 2 2 2 0 Tup N-terminal AAA_17 PF13207.6 KXZ43852.1 - 2.7 8.4 12.0 4.3 7.8 0.1 4.3 4 0 0 4 4 3 0 AAA domain Sugar_tr PF00083.24 KXZ43854.1 - 1.3e-33 116.6 21.9 2.5e-19 69.5 7.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXZ43854.1 - 3e-13 49.4 27.2 3e-13 49.4 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.8 KXZ43854.1 - 0.12 12.1 1.0 0.26 11.1 0.2 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Cation_efflux PF01545.21 KXZ43854.1 - 8.2 6.1 10.8 1.9 8.2 0.2 3.3 3 1 0 3 3 3 0 Cation efflux family TPPK_C PF12555.8 KXZ43855.1 - 0.026 14.5 1.9 2.9 8.0 0.2 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF4235 PF14019.6 KXZ43855.1 - 0.032 14.3 2.1 0.063 13.4 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Usg PF06233.12 KXZ43855.1 - 0.056 13.6 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Usg-like family COX4 PF02936.14 KXZ43855.1 - 0.17 11.9 0.1 0.34 10.9 0.0 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV SPX PF03105.19 KXZ43856.1 - 1 9.2 7.8 1.1 9.0 7.8 1.2 1 0 0 1 1 1 0 SPX domain pKID PF02173.17 KXZ43856.1 - 8.1 6.0 7.2 33 4.1 0.1 3.5 3 0 0 3 3 3 0 pKID domain MttA_Hcf106 PF02416.16 KXZ43857.1 - 1e-19 69.6 0.2 1.6e-19 69.0 0.2 1.3 1 0 0 1 1 1 1 mttA/Hcf106 family EcoEI_R_C PF08463.10 KXZ43858.1 - 0.0015 18.7 1.1 0.0033 17.5 0.2 1.9 2 0 0 2 2 2 1 EcoEI R protein C-terminal MTD PF01993.18 KXZ43858.1 - 0.062 12.6 0.2 0.095 12.0 0.2 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Raptor_N PF14538.6 KXZ43859.1 - 1.5e-67 226.1 0.0 2.3e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KXZ43859.1 - 2.4e-09 37.6 0.4 0.82 10.7 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 KXZ43859.1 - 0.42 11.0 3.0 5.2 7.6 0.1 4.1 4 0 0 4 4 4 0 HEAT repeat zf-ZPR1 PF03367.13 KXZ43860.1 - 1.2e-14 54.4 0.0 2.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 ZPR1 zinc-finger domain F-box-like PF12937.7 KXZ43861.1 - 2.6e-12 46.4 0.2 5.7e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ43861.1 - 7.5e-07 28.9 0.0 3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain DUF3506 PF12014.8 KXZ43861.1 - 0.00053 20.0 0.1 0.0017 18.4 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) Alpha-amylase PF00128.24 KXZ43862.1 - 4.6e-12 46.1 0.0 3.6e-09 36.6 0.0 2.7 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 KXZ43862.1 - 1.4e-09 38.2 0.0 3.6e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 KXZ43862.1 - 1.7e-08 34.8 0.0 1.4e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain TPR_10 PF13374.6 KXZ43863.1 - 0.0062 16.4 0.1 0.025 14.5 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ43863.1 - 0.21 11.9 3.4 0.37 11.1 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat PRK PF00485.18 KXZ43864.1 - 0.0023 17.7 0.0 0.0028 17.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MFS_1 PF07690.16 KXZ43865.1 - 4.1e-09 35.8 20.9 5.5e-09 35.4 20.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ43865.1 - 1.9e-05 23.8 10.7 2.2e-05 23.5 10.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXZ43865.1 - 0.059 12.2 3.7 0.069 12.0 3.7 1.2 1 0 0 1 1 1 0 MFS_1 like family Borealin PF10512.9 KXZ43866.1 - 0.0013 18.7 0.1 0.011 15.7 0.1 2.4 2 0 0 2 2 2 1 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.9 KXZ43866.1 - 0.037 13.7 0.1 0.074 12.7 0.1 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal WD40 PF00400.32 KXZ43873.1 - 5.2e-43 144.2 28.5 4.1e-09 36.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ43873.1 - 7.1e-17 61.5 4.8 0.0014 18.9 0.1 5.8 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ43873.1 - 8.8e-06 25.7 0.1 0.014 15.3 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXZ43873.1 - 0.0062 15.5 0.4 0.72 8.8 0.4 3.4 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXZ43873.1 - 0.015 13.3 0.3 0.027 12.5 0.3 1.4 1 0 0 1 1 1 0 IKI3 family XRN_M PF17846.1 KXZ43874.1 - 0.0033 16.4 0.0 0.0041 16.2 0.0 1.0 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KXZ43876.1 - 1.2e-65 221.3 0.0 7.7e-53 179.4 0.0 2.2 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KXZ43876.1 - 5.8e-31 107.9 0.0 9.3e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Xrn1 helical domain Rpp20 PF12328.8 KXZ43877.1 - 0.005 16.8 0.0 0.0088 16.0 0.0 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Nre_C PF04895.12 KXZ43877.1 - 0.031 14.2 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal Nre, C-terminal CBFD_NFYB_HMF PF00808.23 KXZ43878.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 2.2 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SBE2 PF17076.5 KXZ43878.1 - 6.2 4.9 7.8 8.4 4.5 7.8 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation LRR_4 PF12799.7 KXZ43879.1 - 7.3e-05 23.1 8.6 0.22 12.0 0.1 6.5 5 3 3 8 8 8 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ43879.1 - 0.2 11.4 11.1 5 7.0 0.1 5.9 6 1 1 7 7 7 0 Leucine rich repeat TPR_1 PF00515.28 KXZ43880.1 - 4.6e-09 35.7 9.6 0.056 13.3 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ43880.1 - 7.5e-09 36.0 10.6 0.00017 22.0 5.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ43880.1 - 2.1e-08 34.7 12.5 3e-06 27.8 1.4 4.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ43880.1 - 2.1e-08 33.6 14.7 0.04 14.0 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat 60KD_IMP PF02096.20 KXZ43880.1 - 1e-07 32.0 0.3 0.0037 17.2 0.3 2.2 2 0 0 2 2 2 2 60Kd inner membrane protein TPR_11 PF13414.6 KXZ43880.1 - 8.2e-07 28.6 11.9 3.5e-05 23.4 0.0 4.3 5 0 0 5 5 5 2 TPR repeat ANAPC3 PF12895.7 KXZ43880.1 - 0.0003 20.9 2.8 0.45 10.8 0.5 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXZ43880.1 - 0.00051 20.3 18.4 0.0065 16.7 0.3 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ43880.1 - 0.0048 17.2 0.9 0.18 12.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ43880.1 - 0.031 14.4 0.9 0.031 14.4 0.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ43880.1 - 0.05 14.4 19.3 0.25 12.2 0.0 4.8 3 2 2 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ43880.1 - 0.066 13.6 4.6 1.5 9.2 0.4 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ43880.1 - 0.53 10.6 3.7 1.6e+02 2.9 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 KXZ43881.1 - 9.6e-09 36.0 0.1 1.4e-07 32.3 0.1 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXZ43882.1 - 0.0018 19.1 0.0 0.0035 18.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4200 PF13863.6 KXZ43883.1 - 7.2e-35 120.0 20.9 7.2e-35 120.0 20.9 5.8 5 1 1 6 6 6 2 Domain of unknown function (DUF4200) DUF4407 PF14362.6 KXZ43883.1 - 0.021 14.2 0.1 0.021 14.2 0.1 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4407) DUF2935 PF11155.8 KXZ43883.1 - 4.6 7.6 11.0 2 8.7 0.3 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Spc42p PF11544.8 KXZ43883.1 - 4.6 7.3 13.0 0.51 10.4 0.8 4.0 3 0 0 3 3 3 0 Spindle pole body component Spc42p DDRGK PF09756.9 KXZ43885.1 - 5.3e-51 172.9 7.4 7.2e-51 172.5 7.4 1.1 1 0 0 1 1 1 1 DDRGK domain FeoC PF09012.10 KXZ43885.1 - 0.015 15.4 0.1 0.83 9.8 0.0 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator Presenilin PF01080.17 KXZ43885.1 - 4.8 5.8 9.7 5.8 5.6 9.7 1.1 1 0 0 1 1 1 0 Presenilin Dsh_C PF12316.8 KXZ43885.1 - 5.6 7.3 9.6 7.9 6.8 9.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RR_TM4-6 PF06459.12 KXZ43885.1 - 6.3 6.5 11.2 8.7 6.1 11.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pribosyltran_N PF13793.6 KXZ43886.1 - 1.3e-50 170.2 0.0 3e-50 169.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXZ43886.1 - 3.1e-24 86.0 0.3 1.4e-23 83.9 0.1 2.0 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXZ43886.1 - 2e-17 63.2 1.8 4.3e-17 62.1 1.8 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXZ43886.1 - 0.00012 21.6 0.1 0.00022 20.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Peptidase_M11 PF05548.11 KXZ43887.1 - 2e-63 214.5 2.0 2.6e-63 214.1 2.0 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 KXZ43887.1 - 0.06 12.3 0.2 0.11 11.4 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 ARGLU PF15346.6 KXZ43888.1 - 4.7e-25 88.2 54.6 6e-25 87.9 54.6 1.1 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 Mit_ribos_Mrp51 PF11709.8 KXZ43888.1 - 0.18 11.4 14.5 0.22 11.1 14.5 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF3334 PF11813.8 KXZ43888.1 - 0.94 9.2 5.5 1 9.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Neur_chan_memb PF02932.16 KXZ43888.1 - 5.3 7.0 10.4 7.4 6.6 10.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KXZ43888.1 - 5.8 5.6 15.2 6.6 5.4 15.2 1.1 1 0 0 1 1 1 0 Presenilin Pkinase_Tyr PF07714.17 KXZ43890.1 - 3.2e-33 115.1 0.0 4.7e-19 68.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ43890.1 - 3.3e-28 98.8 0.0 4.1e-21 75.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ43890.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.9 2 2 1 3 3 3 0 Phosphotransferase enzyme family Acyl-ACP_TE PF01643.17 KXZ43891.1 - 1e-49 169.1 0.0 1.2e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 KXZ43891.1 - 0.0013 19.3 0.2 0.094 13.2 0.1 2.8 2 1 0 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.22 KXZ43891.1 - 0.017 15.4 0.2 7 7.1 0.0 3.1 3 0 0 3 3 3 0 Thioesterase superfamily Methyltransf_16 PF10294.9 KXZ43892.1 - 6.7e-12 45.5 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXZ43892.1 - 1.2e-09 38.2 0.0 2.3e-09 37.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ43892.1 - 1.2e-05 25.9 0.0 2.6e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ43892.1 - 0.0035 18.0 0.0 0.0097 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ43892.1 - 0.0073 16.1 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ43892.1 - 0.055 14.1 0.0 0.51 11.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KXZ43892.1 - 0.17 11.2 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB YjeF_N PF03853.15 KXZ43893.1 - 1.2e-34 119.7 0.0 1.9e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus PNP_phzG_C PF10590.9 KXZ43893.1 - 1.6e-20 72.9 1.4 4.1e-20 71.6 1.4 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KXZ43893.1 - 4.8e-16 58.7 0.0 8.7e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KXZ43893.1 - 0.00019 22.0 0.0 0.00034 21.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ureidogly_lyase PF04115.12 KXZ43895.1 - 5.6e-06 26.2 0.0 0.0041 16.9 0.0 2.1 1 1 0 2 2 2 2 Ureidoglycolate lyase DUF4600 PF15372.6 KXZ43898.1 - 0.0022 18.4 1.8 0.0022 18.4 1.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) CC2-LZ PF16516.5 KXZ43898.1 - 0.0081 16.5 2.8 0.0081 16.5 2.8 2.7 1 1 1 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Arm PF00514.23 KXZ43898.1 - 0.021 14.8 1.5 4.7 7.4 0.1 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF812 PF05667.11 KXZ43898.1 - 7.9 5.2 16.4 2.6 6.8 13.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) G6PD_C PF02781.16 KXZ43899.1 - 1.1e-107 359.5 0.0 1.5e-107 359.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXZ43899.1 - 7.1e-56 189.6 0.0 1.1e-55 189.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain LSM14 PF12701.7 KXZ43900.1 - 4.3e-29 100.4 0.1 6.2e-29 99.9 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KXZ43900.1 - 2.8e-07 30.6 0.0 4.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 KXZ43900.1 - 4.3e-05 24.3 6.6 0.035 15.0 5.2 2.3 1 1 1 2 2 2 2 FDF domain Totivirus_coat PF05518.11 KXZ43900.1 - 3.2 5.7 9.8 4.5 5.2 9.8 1.3 1 0 0 1 1 1 0 Totivirus coat protein DUF179 PF02622.15 KXZ43902.1 - 6.9e-31 107.4 0.0 1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Dam PF05869.11 KXZ43903.1 - 4.9e-10 39.2 0.0 7.7e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) TPR_10 PF13374.6 KXZ43904.1 - 0.089 12.7 5.1 5.1 7.1 1.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DAGAT PF03982.13 KXZ43905.1 - 4.7e-15 55.3 0.0 2.8e-06 26.5 0.0 3.1 3 0 0 3 3 3 3 Diacylglycerol acyltransferase ADK PF00406.22 KXZ43906.1 - 1e-77 259.4 0.0 6.9e-45 152.8 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KXZ43906.1 - 1.2e-49 168.3 6.6 3.1e-30 105.3 0.0 3.8 3 1 0 3 3 2 2 AAA domain IQ PF00612.27 KXZ43906.1 - 9.6e-14 49.8 20.8 0.0047 16.6 1.0 4.6 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_33 PF13671.6 KXZ43906.1 - 3e-12 46.9 0.0 2.3e-05 24.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXZ43906.1 - 4.1e-10 40.3 0.0 0.00047 20.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 KXZ43906.1 - 0.00014 21.6 0.0 0.38 10.4 0.0 3.9 4 0 0 4 4 4 1 Thymidylate kinase Ploopntkinase3 PF18751.1 KXZ43906.1 - 0.0023 17.9 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 tRNA_lig_kinase PF08303.11 KXZ43906.1 - 0.0039 17.3 0.1 0.28 11.3 0.0 2.3 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_22 PF13401.6 KXZ43906.1 - 0.015 15.6 0.3 6.8 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain UBA_6 PF18039.1 KXZ43906.1 - 0.025 14.5 5.2 23 5.0 0.0 4.7 5 0 0 5 5 5 0 UBA-like domain AAA PF00004.29 KXZ43906.1 - 0.033 14.6 0.2 4 7.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXZ43906.1 - 0.045 12.9 0.2 6.7 5.8 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 KXZ43906.1 - 0.06 13.7 0.0 11 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXZ43906.1 - 0.076 13.5 0.2 15 6.1 0.0 2.8 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 KXZ43906.1 - 0.2 11.6 0.5 5.5 6.9 0.1 2.3 2 0 0 2 2 2 0 NTPase DUF3139 PF11337.8 KXZ43906.1 - 0.21 12.3 0.0 71 4.2 0.0 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF3139) Viral_helicase1 PF01443.18 KXZ43906.1 - 0.21 11.3 0.6 21 4.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF494 PF04361.13 KXZ43906.1 - 0.24 11.3 7.6 49 3.8 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF494) CoaE PF01121.20 KXZ43906.1 - 0.32 10.6 4.8 22 4.7 0.0 4.8 6 0 0 6 6 5 0 Dephospho-CoA kinase Guanylate_kin PF00625.21 KXZ43907.1 - 8.9e-27 93.9 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase Dpy-30 PF05186.13 KXZ43907.1 - 5.3e-10 38.8 0.0 7.6e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 KXZ43907.1 - 4.6e-05 23.0 0.1 7.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Atg14 PF10186.9 KXZ43908.1 - 2.1e-08 33.7 0.2 1e-05 24.8 0.4 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 YfhD PF14151.6 KXZ43908.1 - 0.13 12.5 1.9 0.36 11.0 1.9 1.7 1 0 0 1 1 1 0 YfhD-like protein Yippee-Mis18 PF03226.14 KXZ43909.1 - 7.6e-16 58.2 0.5 8.8e-16 58.0 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 KXZ43909.1 - 0.01 16.0 0.4 0.016 15.4 0.2 1.6 1 1 0 1 1 1 0 TPL-binding domain in jasmonate signalling RIG-I_C-RD PF11648.8 KXZ43909.1 - 0.027 14.7 0.6 0.038 14.2 0.6 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I Endonuclease_7 PF02945.15 KXZ43909.1 - 0.19 11.6 3.0 0.48 10.4 2.9 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII IBN_N PF03810.19 KXZ43911.1 - 7.5e-13 48.2 0.2 1.6e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KXZ43911.1 - 3e-05 23.7 0.0 4.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 KXZ43911.1 - 0.037 14.3 0.0 0.037 14.3 0.0 3.9 5 0 0 5 5 5 0 HEAT repeat TAF6_C PF07571.13 KXZ43911.1 - 0.076 13.3 0.1 0.46 10.8 0.0 2.2 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 KXZ43911.1 - 0.2 11.7 0.0 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Pollen_allerg_1 PF01357.21 KXZ43913.1 - 0.00051 20.0 0.0 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 Pollen allergen DPBB_1 PF03330.18 KXZ43913.1 - 0.00069 19.9 0.3 0.0054 17.0 0.4 2.4 2 1 0 2 2 2 1 Lytic transglycolase Bd3614-deam PF14439.6 KXZ43914.1 - 0.039 14.0 0.3 0.046 13.8 0.3 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase WD40 PF00400.32 KXZ43915.1 - 1.7e-24 85.6 14.4 0.00069 20.4 0.0 11.6 11 2 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ43915.1 - 5.7e-07 29.8 0.3 0.06 13.7 0.0 4.4 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NUDIX_2 PF13869.6 KXZ43916.1 - 3.8e-40 137.5 0.0 4.7e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Dynamitin PF04912.14 KXZ43916.1 - 0.017 14.4 0.1 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 Dynamitin Polyketide_cyc2 PF10604.9 KXZ43920.1 - 3.3e-10 40.4 0.0 3.6e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KXZ43920.1 - 0.13 12.5 0.3 0.18 12.0 0.2 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport JAB PF01398.21 KXZ43921.1 - 1.4e-23 83.1 0.0 1.9e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KXZ43921.1 - 1.8e-19 70.5 0.0 2.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KXZ43921.1 - 0.1 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Ank_4 PF13637.6 KXZ43922.1 - 2e-09 37.8 4.3 0.6 10.8 0.0 8.2 4 3 7 11 11 11 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43922.1 - 5e-09 36.6 0.1 0.2 12.2 0.0 5.3 2 2 4 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43922.1 - 8.1e-06 25.8 5.5 1.6 9.5 0.0 7.2 10 0 0 10 10 10 2 Ankyrin repeat EF-hand_8 PF13833.6 KXZ43923.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ43923.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KXZ43923.1 - 0.073 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KXZ43923.1 - 0.099 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 KXZ43924.1 - 2.1e-16 60.1 0.0 6.1e-16 58.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43924.1 - 1.4e-05 24.5 0.1 7.9e-05 22.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ43924.1 - 6.5e-05 23.0 1.1 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3694 PF12473.8 KXZ43924.1 - 0.00085 20.0 0.0 0.0074 17.0 0.0 2.1 1 1 0 1 1 1 1 Kinesin protein ATX_III PF08098.11 KXZ43924.1 - 0.0045 17.0 0.9 0.012 15.6 0.9 1.7 1 0 0 1 1 1 1 Anemonia sulcata toxin III family ABC_membrane PF00664.23 KXZ43925.1 - 3.4e-99 331.9 31.5 1.7e-53 182.1 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ43925.1 - 3.6e-69 231.6 0.0 2.9e-33 115.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXZ43925.1 - 1.3e-11 44.3 3.2 0.0046 16.4 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ43925.1 - 4.6e-08 32.7 0.8 0.0088 15.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ43925.1 - 9.7e-08 32.6 0.5 0.021 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXZ43925.1 - 1e-06 29.1 0.1 0.22 11.8 0.0 3.9 3 2 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KXZ43925.1 - 1.3e-05 25.1 0.0 0.083 12.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KXZ43925.1 - 1.4e-05 24.5 0.0 0.039 13.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ABC_ATPase PF09818.9 KXZ43925.1 - 8.8e-05 21.5 5.1 0.12 11.1 0.0 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXZ43925.1 - 0.00015 21.7 0.8 0.23 11.4 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KXZ43925.1 - 0.00034 20.8 0.5 1.1 9.4 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain APS_kinase PF01583.20 KXZ43925.1 - 0.00047 20.1 0.1 0.52 10.2 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_5 PF07728.14 KXZ43925.1 - 0.0008 19.4 1.2 2.4 8.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KXZ43925.1 - 0.00093 18.4 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 KXZ43925.1 - 0.0017 18.1 8.4 0.28 10.9 0.2 3.6 3 2 0 3 3 2 2 AAA domain AAA_21 PF13304.6 KXZ43925.1 - 0.002 18.0 0.1 2.2 8.0 0.0 2.9 3 1 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXZ43925.1 - 0.004 17.7 0.2 1.8 9.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXZ43925.1 - 0.0044 17.2 0.1 2.3 8.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KXZ43925.1 - 0.011 15.3 2.7 0.47 10.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 KXZ43925.1 - 0.014 14.9 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PRK PF00485.18 KXZ43925.1 - 0.014 15.1 0.2 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 KXZ43925.1 - 0.028 13.6 0.0 8.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF3987 PF13148.6 KXZ43925.1 - 0.038 13.0 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_18 PF13238.6 KXZ43925.1 - 0.081 13.5 0.1 8.6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXZ43925.1 - 0.084 12.6 0.1 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXZ43925.1 - 0.13 12.2 0.8 7.6 6.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 KXZ43925.1 - 0.15 12.0 2.8 28 4.6 0.0 3.6 3 1 0 4 4 4 0 NTPase SbcCD_C PF13558.6 KXZ43925.1 - 0.68 10.2 9.4 5.9 7.2 0.5 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Kinesin PF00225.23 KXZ43927.1 - 1e-87 294.2 0.0 3.9e-87 292.3 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ43927.1 - 3.7e-18 65.9 0.0 6.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding WW PF00397.26 KXZ43927.1 - 0.0029 17.7 1.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 2 WW domain Takusan PF04822.13 KXZ43927.1 - 0.21 11.5 3.6 12 5.9 0.1 3.3 3 0 0 3 3 3 0 Takusan Ribosomal_L33 PF00471.20 KXZ43928.1 - 1.5e-20 73.3 0.9 2.3e-20 72.7 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L33 PPP4R2 PF09184.11 KXZ43929.1 - 1.8e-14 54.0 0.0 2.2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 PPP4R2 DUF202 PF02656.15 KXZ43930.1 - 2.2e-11 44.0 0.9 2.2e-11 44.0 0.9 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF202) VTC PF09359.10 KXZ43931.1 - 5.7e-68 229.3 0.0 2.2e-55 188.0 0.0 2.2 2 0 0 2 2 2 2 VTC domain VTC PF09359.10 KXZ43932.1 - 3.4e-07 29.9 0.0 5.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 VTC domain RabGAP-TBC PF00566.18 KXZ43934.1 - 2.6e-42 144.9 0.2 6.5e-42 143.6 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PseudoU_synth_2 PF00849.22 KXZ43935.1 - 9.8e-18 64.7 0.1 1.2e-16 61.2 0.1 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase CAP_N PF01213.19 KXZ43935.1 - 0.34 10.4 2.0 0.51 9.8 2.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ECH_1 PF00378.20 KXZ43936.1 - 1.9e-34 119.1 3.0 4.2e-27 95.1 0.4 2.7 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXZ43936.1 - 8.3e-19 68.3 0.3 2.8e-18 66.5 0.3 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Cu2_monooxygen PF01082.20 KXZ43937.1 - 2.1e-29 102.4 0.0 4.4e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KXZ43937.1 - 2.7e-27 95.2 0.0 4.2e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 KXZ43937.1 - 1.3e-06 28.6 0.0 3e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 DOMON domain DUF4366 PF14283.6 KXZ43937.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Ank_4 PF13637.6 KXZ43938.1 - 5.6e-14 52.3 4.0 0.0034 17.9 0.1 7.5 6 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43938.1 - 2.1e-09 37.8 0.0 0.00091 19.8 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43938.1 - 1.8e-07 30.9 0.7 1.7 9.4 0.0 7.0 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KXZ43938.1 - 1.2e-05 25.5 0.3 3.4 8.1 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ad_Cy_reg PF16701.5 KXZ43938.1 - 0.016 14.9 0.1 8.7 6.0 0.0 4.4 5 1 0 5 5 5 0 Adenylate cyclase regulatory domain HTH_8 PF02954.19 KXZ43938.1 - 0.017 14.9 3.7 0.022 14.6 0.3 2.9 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family DUF434 PF04256.12 KXZ43938.1 - 0.2 11.4 0.0 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF434) Hpt PF01627.23 KXZ43939.1 - 0.018 15.3 0.1 0.065 13.5 0.1 2.0 1 1 0 1 1 1 0 Hpt domain DNA_methylase PF00145.17 KXZ43940.1 - 2.8e-31 109.1 0.0 9.2e-21 74.5 0.0 3.2 3 0 0 3 3 3 3 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 KXZ43940.1 - 1.7e-23 83.3 0.0 1.9e-12 47.4 0.0 2.8 2 1 0 2 2 2 2 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 KXZ43940.1 - 0.0099 15.7 0.0 15 5.4 0.0 3.8 4 0 0 4 4 4 2 BAH domain TIG PF01833.24 KXZ43941.1 - 8.4e-63 208.5 70.2 4.4e-12 45.9 4.0 13.7 12 0 0 12 12 12 10 IPT/TIG domain G8 PF10162.9 KXZ43941.1 - 8.2e-59 197.1 0.0 2.6e-28 98.5 0.0 2.9 2 0 0 2 2 2 2 G8 domain PA14 PF07691.12 KXZ43941.1 - 8.8e-05 22.3 0.5 0.0054 16.5 0.0 2.6 2 0 0 2 2 2 1 PA14 domain Beta_helix PF13229.6 KXZ43941.1 - 0.00015 21.6 20.9 0.0052 16.7 4.8 4.7 4 1 0 5 5 5 3 Right handed beta helix region Cu2_monoox_C PF03712.15 KXZ43942.1 - 1.8e-30 105.6 0.0 3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KXZ43942.1 - 7.1e-30 103.9 0.1 1.9e-29 102.5 0.1 1.8 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KXZ43942.1 - 7.2e-12 45.6 0.0 2.1e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 DOMON domain Syndecan PF01034.20 KXZ43942.1 - 1.1 9.2 2.4 2.7 8.0 2.4 1.6 1 0 0 1 1 1 0 Syndecan domain Sec1 PF00995.23 KXZ43944.1 - 2.7e-99 334.0 0.0 3.1e-99 333.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ank_4 PF13637.6 KXZ43945.1 - 4.4e-10 39.9 5.9 0.1 13.2 0.0 6.3 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ43945.1 - 1.2e-09 38.6 0.6 0.014 15.9 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ43945.1 - 1.9e-05 24.7 2.0 47 5.0 0.0 8.1 8 1 1 9 9 9 0 Ankyrin repeat Ank_5 PF13857.6 KXZ43945.1 - 0.00048 20.4 4.2 34 4.9 0.1 5.7 3 1 2 5 5 5 1 Ankyrin repeats (many copies) SIR2 PF02146.17 KXZ43946.1 - 6.3e-27 94.6 0.0 2.6e-18 66.6 0.0 2.2 1 1 1 2 2 2 2 Sir2 family RRM_1 PF00076.22 KXZ43947.1 - 3.2e-15 55.7 0.0 4.6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXZ43947.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ndc1_Nup PF09531.10 KXZ43947.1 - 8.4 4.9 13.9 11 4.6 13.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aminotran_5 PF00266.19 KXZ43949.1 - 1.6e-30 106.3 0.0 1.9e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V NIPSNAP PF07978.13 KXZ43949.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 NIPSNAP Ion_trans_2 PF07885.16 KXZ43950.1 - 1.1e-12 47.7 1.4 1.1e-12 47.7 1.4 2.5 2 1 1 3 3 3 1 Ion channel Ion_trans PF00520.31 KXZ43950.1 - 4.4e-10 39.2 11.0 7.4e-10 38.5 11.0 1.3 1 0 0 1 1 1 1 Ion transport protein BK_channel_a PF03493.18 KXZ43950.1 - 1.6e-06 28.2 0.1 0.00088 19.4 0.3 2.4 1 1 1 2 2 2 2 Calcium-activated BK potassium channel alpha subunit WTF PF03303.13 KXZ43950.1 - 0.82 9.3 3.8 0.36 10.5 0.4 2.0 2 1 0 2 2 2 0 WTF protein Galactosyl_T PF01762.21 KXZ43951.1 - 2.9e-20 72.9 0.0 7e-19 68.4 0.0 2.0 2 0 0 2 2 2 2 Galactosyltransferase BACK PF07707.15 KXZ43952.1 - 0.00013 22.0 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ43952.1 - 0.0047 17.1 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain KNOX2 PF03791.13 KXZ43952.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 KNOX2 domain BACK PF07707.15 KXZ43953.1 - 1.7e-05 24.8 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ43953.1 - 0.17 12.1 0.0 0.72 10.1 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain Pkinase PF00069.25 KXZ43956.1 - 7.2e-12 45.2 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ43956.1 - 2e-05 24.7 0.2 5.8e-05 23.1 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ43956.1 - 0.002 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ43956.1 - 0.0051 16.1 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43956.1 - 0.06 12.1 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KXZ43956.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KXZ43958.1 - 3.7e-11 42.9 0.0 5.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ43958.1 - 7.1e-06 26.1 0.5 3.4e-05 23.9 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ43958.1 - 0.0008 18.8 0.1 0.0019 17.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ43958.1 - 0.007 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ43958.1 - 0.075 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KXZ43958.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase NeA_P2 PF12312.8 KXZ43961.1 - 0.25 10.8 6.6 2 7.8 1.7 2.6 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein SOG2 PF10428.9 KXZ43962.1 - 0.07 12.3 6.7 0.074 12.2 6.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KXZ43962.1 - 1 8.2 5.6 1.1 8.1 5.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_3_Rpc31 PF11705.8 KXZ43967.1 - 0.0092 16.3 19.7 0.024 14.9 3.9 2.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 KXZ43967.1 - 0.028 14.1 11.7 0.61 9.7 2.3 2.4 2 0 0 2 2 2 0 FAM176 family GEN1_C PF18380.1 KXZ43967.1 - 0.077 13.9 10.6 0.29 12.1 1.9 2.7 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain PBP1_TM PF14812.6 KXZ43967.1 - 0.086 13.2 12.6 0.15 12.5 2.8 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KXZ43967.1 - 0.31 10.3 17.7 0.22 10.8 5.0 2.4 2 0 0 2 2 2 0 NOA36 protein SDA1 PF05285.12 KXZ43967.1 - 0.42 10.0 16.5 1.2 8.5 3.9 2.2 2 0 0 2 2 2 0 SDA1 Na_trans_assoc PF06512.13 KXZ43967.1 - 0.49 10.6 8.9 2.1 8.6 0.7 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated Radial_spoke PF04712.12 KXZ43967.1 - 0.53 9.2 23.0 0.15 11.0 4.3 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein DUF4604 PF15377.6 KXZ43967.1 - 0.76 10.2 9.9 7.1 7.0 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) TFB6 PF17110.5 KXZ43967.1 - 1 9.1 7.2 7.4 6.3 1.2 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF2052 PF09747.9 KXZ43967.1 - 1.1 9.3 25.4 0.045 13.9 1.2 2.5 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1676 PF07898.13 KXZ43967.1 - 1.4 8.9 7.7 0.23 11.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) LAT PF15234.6 KXZ43967.1 - 1.9 8.2 10.9 4 7.1 0.5 2.4 2 0 0 2 2 2 0 Linker for activation of T-cells Nop14 PF04147.12 KXZ43967.1 - 2.9 6.0 18.5 0.64 8.2 2.3 2.2 2 0 0 2 2 2 0 Nop14-like family MRNIP PF15749.5 KXZ43967.1 - 3.3 8.5 5.0 43 4.9 0.1 2.3 2 0 0 2 2 2 0 MRN-interacting protein BSP_II PF05432.11 KXZ43967.1 - 3.3 7.3 33.5 0.064 13.0 5.5 2.4 3 0 0 3 3 2 0 Bone sialoprotein II (BSP-II) Mak16 PF04874.14 KXZ43967.1 - 4.3 8.0 25.7 7.3 7.3 8.2 2.7 2 0 0 2 2 2 0 Mak16 protein C-terminal region Cwf_Cwc_15 PF04889.12 KXZ43967.1 - 4.4 7.0 16.8 4.2 7.0 1.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PTPRCAP PF15713.5 KXZ43967.1 - 6.3 7.1 27.0 1 9.6 3.3 3.5 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Tub_N PF16322.5 KXZ43967.1 - 6.4 7.1 12.3 14 6.0 2.8 2.3 2 0 0 2 2 2 0 Tubby N-terminal PAXIP1_C PF15364.6 KXZ43967.1 - 8.1 6.8 14.0 2 8.7 1.3 2.6 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein MAM33 PF02330.16 KXZ43967.1 - 8.4 6.3 15.2 7.2 6.5 3.2 2.9 3 0 0 3 3 3 0 Mitochondrial glycoprotein DUF4539 PF15072.6 KXZ43968.1 - 6.8e-20 70.9 0.0 9.9e-20 70.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) UBX PF00789.20 KXZ43969.1 - 0.0018 18.4 0.1 0.051 13.8 0.1 2.2 2 0 0 2 2 2 1 UBX domain NQRA_SLBB PF11973.8 KXZ43969.1 - 0.2 12.3 0.0 0.39 11.4 0.0 1.5 1 0 0 1 1 1 0 NQRA C-terminal domain SNF2_N PF00176.23 KXZ43971.1 - 2.3e-49 168.0 0.0 7.5e-49 166.3 0.0 1.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ43971.1 - 2.5e-07 31.0 0.0 5.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ43971.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXZ43971.1 - 0.079 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MORN PF02493.20 KXZ43972.1 - 2.7e-29 99.3 13.0 1.4e-06 27.9 0.5 6.6 6 0 0 6 6 6 6 MORN repeat TerD PF02342.18 KXZ43972.1 - 8.7e-05 22.1 0.0 0.00073 19.1 0.0 2.4 3 0 0 3 3 3 1 TerD domain Tim54 PF11711.8 KXZ43972.1 - 0.07 11.9 2.9 0.13 11.0 2.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_M11 PF05548.11 KXZ43973.1 - 7e-38 130.5 0.2 9.6e-38 130.1 0.2 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_5 PF13688.6 KXZ43973.1 - 0.00089 19.5 1.6 0.0017 18.5 1.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KXZ43973.1 - 0.0024 17.7 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KXZ43973.1 - 0.0033 16.4 0.1 0.0049 15.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 KXZ43973.1 - 0.0053 16.4 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KXZ43973.1 - 0.0071 16.9 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KXZ43973.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Cu-binding_MopE PF11617.8 KXZ43973.1 - 0.03 14.5 7.5 0.03 14.5 7.5 2.1 1 1 1 2 2 2 0 Putative metal-binding motif Reprolysin_2 PF13574.6 KXZ43973.1 - 0.055 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4995 PF16386.5 KXZ43973.1 - 0.056 13.5 0.4 0.47 10.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function DUF4953 PF16313.5 KXZ43973.1 - 0.085 12.1 0.2 0.18 11.0 0.1 1.5 2 0 0 2 2 2 0 Met-zincin Peptidase_M57 PF12388.8 KXZ43973.1 - 0.11 12.1 0.3 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M11 PF05548.11 KXZ43974.1 - 1.4e-33 116.4 0.2 1e-31 110.3 0.0 2.0 1 1 1 2 2 2 2 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 KXZ43974.1 - 0.0016 17.5 0.3 0.0026 16.8 0.3 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_5 PF13688.6 KXZ43974.1 - 0.0016 18.6 0.2 0.0032 17.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KXZ43974.1 - 0.0023 17.8 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Cu-binding_MopE PF11617.8 KXZ43974.1 - 0.0025 17.9 3.2 0.006 16.7 3.2 1.6 1 0 0 1 1 1 1 Putative metal-binding motif Reprolysin_4 PF13583.6 KXZ43974.1 - 0.0084 15.8 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXZ43974.1 - 0.021 14.7 0.2 0.051 13.5 0.2 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KXZ43974.1 - 0.022 15.3 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KXZ43974.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KXZ43974.1 - 0.076 12.2 0.1 0.19 10.9 0.1 1.6 2 0 0 2 2 2 0 Met-zincin Peptidase_M57 PF12388.8 KXZ43974.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF5412 PF17428.2 KXZ43974.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5412) Kinesin PF00225.23 KXZ43975.1 - 3.8e-98 328.5 0.2 2.7e-97 325.7 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ43975.1 - 1.4e-19 70.5 0.2 3.9e-18 65.8 0.0 2.9 3 0 0 3 3 3 1 Microtubule binding SKA2 PF16740.5 KXZ43976.1 - 6.9e-07 29.0 1.2 0.024 14.4 0.0 2.5 1 1 1 2 2 2 2 Spindle and kinetochore-associated protein 2 Mito_carr PF00153.27 KXZ43977.1 - 5e-63 209.1 0.6 2.8e-25 88.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein T6SS_TssF PF05947.12 KXZ43977.1 - 0.04 12.5 0.0 0.052 12.1 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssF DivIVA PF05103.13 KXZ43978.1 - 0.091 12.8 2.1 0.24 11.5 2.1 1.6 1 0 0 1 1 1 0 DivIVA protein DUF1525 PF07511.11 KXZ43978.1 - 0.14 12.3 0.9 0.38 10.9 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) CDC27 PF09507.10 KXZ43981.1 - 2.1e-18 66.9 36.9 3.9e-16 59.5 36.9 2.2 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Guanylate_cyc PF00211.20 KXZ43981.1 - 4.6e-09 36.2 1.9 0.015 14.9 0.0 3.3 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain Meckelin PF09773.9 KXZ43981.1 - 0.26 9.3 0.5 0.38 8.8 0.5 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DNA_methylase PF00145.17 KXZ43983.1 - 9.6e-16 58.0 0.0 2.7e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase DNA_methylase PF00145.17 KXZ43984.1 - 2.7e-08 33.6 0.0 1.6e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Glyco_hydro_18 PF00704.28 KXZ43985.1 - 5.5e-10 39.5 0.0 8.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Kinesin PF00225.23 KXZ43987.1 - 1.3e-93 313.6 0.0 2.9e-93 312.4 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ43987.1 - 2.6e-47 160.5 0.0 6.6e-47 159.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Fez1 PF06818.15 KXZ43987.1 - 0.0052 17.3 23.6 0.0052 17.3 23.6 4.4 1 1 3 4 4 4 2 Fez1 DUF1515 PF07439.11 KXZ43987.1 - 0.0075 16.3 2.9 0.0075 16.3 2.9 4.5 4 1 1 5 5 5 1 Protein of unknown function (DUF1515) FAST_1 PF06743.15 KXZ43987.1 - 0.022 14.7 1.6 3.2 7.8 0.0 4.2 4 1 1 5 5 5 0 FAST kinase-like protein, subdomain 1 RicinB_lectin_2 PF14200.6 KXZ43988.1 - 8.6e-33 112.9 18.0 7.4e-16 58.7 2.7 4.5 1 1 4 5 5 5 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ43988.1 - 5.7e-27 94.5 1.0 7.6e-13 48.8 0.1 3.0 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ43988.1 - 7.7e-14 52.2 1.5 1.7e-13 51.0 0.4 1.7 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ43988.1 - 8.5e-07 28.7 0.4 0.058 13.0 0.1 2.9 1 1 2 3 3 3 2 Cytolethal distending toxin A/C domain PAP_fibrillin PF04755.12 KXZ43989.1 - 4.4e-34 118.2 0.0 7e-34 117.5 0.0 1.3 1 1 0 1 1 1 1 PAP_fibrillin zf-MYND PF01753.18 KXZ43991.1 - 9.8e-10 38.4 10.0 2.2e-09 37.3 10.0 1.6 1 0 0 1 1 1 1 MYND finger CaATP_NAI PF12515.8 KXZ43992.1 - 0.13 11.9 0.1 0.88 9.2 0.0 2.0 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain RSN1_7TM PF02714.15 KXZ43993.1 - 1.6e-32 113.0 2.4 4.6e-19 68.8 0.8 2.1 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXZ43993.1 - 0.00095 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter CS PF04969.16 KXZ43994.1 - 0.21 12.6 0.0 0.35 11.9 0.0 1.3 1 0 0 1 1 1 0 CS domain Pkinase PF00069.25 KXZ43995.1 - 7e-54 182.9 0.0 1e-53 182.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ43995.1 - 9e-30 103.8 0.0 1.7e-28 99.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ43995.1 - 2.1e-06 27.2 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ43995.1 - 0.011 15.6 0.0 0.011 15.6 0.0 3.3 3 2 1 4 4 4 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ43995.1 - 0.048 12.4 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KXZ43995.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KXZ43995.1 - 0.23 10.4 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4710 PF15828.5 KXZ43996.1 - 0.2 11.8 1.7 0.33 11.1 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) FlaC_arch PF05377.11 KXZ43997.1 - 0.0044 17.4 0.8 0.0044 17.4 0.8 14.7 17 2 1 18 18 18 3 Flagella accessory protein C (FlaC) MutS_V PF00488.21 KXZ43998.1 - 2.2e-44 151.7 0.3 4.5e-44 150.7 0.3 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXZ43998.1 - 1.3e-20 74.5 0.0 2.3e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXZ43998.1 - 4.8e-18 65.4 0.0 7.9e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXZ43998.1 - 0.00016 21.9 0.0 0.00039 20.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain II Macoilin PF09726.9 KXZ43998.1 - 2.4 6.6 14.8 3.3 6.1 14.8 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KXZ43998.1 - 4.5 6.0 14.2 6.1 5.6 14.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mito_carr PF00153.27 KXZ44000.1 - 1.3e-44 150.1 5.1 1.4e-17 63.4 0.0 4.3 3 2 1 4 4 4 3 Mitochondrial carrier protein Adeno_PIX PF03955.14 KXZ44000.1 - 0.29 11.3 2.8 0.67 10.2 0.4 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Tim17 PF02466.19 KXZ44000.1 - 0.55 10.6 4.0 14 6.1 0.1 2.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family AAA PF00004.29 KXZ44001.1 - 5.2e-39 133.7 0.0 1e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ44001.1 - 2e-10 40.3 0.4 7.7e-10 38.4 0.4 2.0 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXZ44001.1 - 2.1e-08 34.1 0.0 0.00055 19.7 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXZ44001.1 - 3e-05 24.0 0.1 0.00047 20.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 KXZ44001.1 - 3.6e-05 23.7 0.0 7.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KXZ44001.1 - 0.00015 22.1 0.0 0.00053 20.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXZ44001.1 - 0.00055 19.6 0.4 0.083 12.5 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KXZ44001.1 - 0.0007 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXZ44001.1 - 0.001 19.5 0.9 0.001 19.5 0.9 3.1 2 2 0 2 2 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KXZ44001.1 - 0.0027 17.1 0.0 0.0069 15.8 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KXZ44001.1 - 0.0031 16.8 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KXZ44001.1 - 0.0037 17.3 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXZ44001.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXZ44001.1 - 0.014 15.2 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KXZ44001.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KXZ44001.1 - 0.022 15.3 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXZ44001.1 - 0.04 14.2 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ44001.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KXZ44001.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXZ44001.1 - 0.095 12.1 0.0 0.44 9.9 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein Guanylate_kin PF00625.21 KXZ44001.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase DUF815 PF05673.13 KXZ44001.1 - 0.22 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MIT PF04212.18 KXZ44001.1 - 2.8 8.1 5.4 0.29 11.2 0.2 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF824 PF05688.11 KXZ44002.1 - 0.066 13.1 0.1 0.09 12.6 0.1 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Cohesin PF00963.18 KXZ44002.1 - 0.097 12.9 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Cohesin domain Acetyltransf_1 PF00583.25 KXZ44003.1 - 3.2e-20 72.5 0.1 3.7e-20 72.3 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ44003.1 - 4.3e-12 46.1 0.0 5.3e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ44003.1 - 7.8e-11 42.3 0.1 1.1e-10 41.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXZ44003.1 - 1.7e-07 31.4 0.0 2.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ44003.1 - 3.1e-06 27.2 0.1 4.6e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 KXZ44003.1 - 0.00036 20.7 0.1 0.0007 19.8 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KXZ44003.1 - 0.071 12.7 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase DUF647 PF04884.14 KXZ44004.1 - 6.5e-61 206.0 0.0 8.5e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RRM_1 PF00076.22 KXZ44005.1 - 5.7e-36 122.2 0.0 1.5e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ44005.1 - 1.8e-12 47.2 0.0 4.6e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KXZ44005.1 - 0.0039 17.2 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif PHM7_cyt PF14703.6 KXZ44005.1 - 0.0063 16.8 0.0 0.1 12.8 0.0 2.4 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KXZ44005.1 - 0.019 15.0 0.1 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 KXZ44006.1 - 5.9e-64 216.0 0.0 7.4e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44006.1 - 6.1e-44 150.2 0.0 7.6e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ44006.1 - 5.4e-07 28.7 0.0 7.8e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ44006.1 - 5.3e-05 22.7 0.0 0.00013 21.4 0.0 1.6 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KXZ44006.1 - 0.0098 15.5 0.2 0.68 9.5 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 KXZ44006.1 - 0.05 12.6 0.1 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 KXZ44006.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KXZ44006.1 - 0.14 12.1 0.1 0.84 9.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DnaJ PF00226.31 KXZ44007.1 - 4.4e-18 65.1 0.2 1.3e-17 63.6 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain KH_1 PF00013.29 KXZ44007.1 - 6.2e-15 54.8 2.9 2e-14 53.2 2.9 1.9 1 1 0 1 1 1 1 KH domain SLS PF14611.6 KXZ44007.1 - 0.0008 19.3 0.6 1 9.1 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KXZ44007.1 - 0.0037 17.0 0.1 0.01 15.7 0.1 1.7 1 0 0 1 1 1 1 KH domain MOEP19 PF16005.5 KXZ44007.1 - 0.019 15.0 0.2 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain Fer2 PF00111.27 KXZ44008.1 - 0.00022 21.1 0.2 0.0003 20.7 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ANAPC4_WD40 PF12894.7 KXZ44010.1 - 2.3e-14 53.5 0.1 0.0053 17.0 0.0 4.9 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ44010.1 - 4.3e-14 52.7 12.0 0.0014 19.4 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat VasI PF11319.8 KXZ44010.1 - 0.019 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 PD40 PF07676.12 KXZ44010.1 - 0.083 12.9 0.1 19 5.3 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KXZ44010.1 - 0.091 12.1 0.5 3.9 6.7 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal MAPEG PF01124.18 KXZ44011.1 - 1.1e-17 64.2 0.1 1.4e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 MAPEG family CAP PF00188.26 KXZ44012.1 - 7.5e-22 78.5 2.5 1.3e-21 77.7 2.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sad1_UNC PF07738.13 KXZ44013.1 - 0.052 13.6 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal ELMO_CED12 PF04727.13 KXZ44016.1 - 1.7e-45 155.3 0.0 4.6e-43 147.4 0.0 2.1 2 0 0 2 2 2 2 ELMO/CED-12 family Dynamin_N PF00350.23 KXZ44017.1 - 1.6e-09 38.0 1.3 1.6e-08 34.8 0.2 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXZ44017.1 - 7.1e-08 32.5 0.0 1.9e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 KXZ44017.1 - 0.00072 18.7 0.4 0.41 9.6 0.0 2.2 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KXZ44017.1 - 0.0097 16.1 0.1 0.021 15.1 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXZ44017.1 - 0.43 10.5 4.2 0.41 10.5 0.1 3.0 4 0 0 4 4 4 0 RsgA GTPase DAO PF01266.24 KXZ44018.1 - 9.9e-13 48.4 3.7 1.3e-12 48.0 3.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXZ44018.1 - 2.5e-10 40.0 0.4 3.2e-10 39.7 0.4 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXZ44018.1 - 6e-08 32.2 3.4 8e-08 31.8 3.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXZ44018.1 - 2.6e-07 30.8 3.4 5e-07 29.8 3.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ44018.1 - 5.9e-06 25.7 1.9 8e-06 25.3 1.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ44018.1 - 2.8e-05 23.7 4.0 3.4e-05 23.4 4.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXZ44018.1 - 3.3e-05 23.3 3.7 4e-05 23.0 3.7 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXZ44018.1 - 8.2e-05 21.9 3.4 0.0001 21.5 3.4 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXZ44018.1 - 0.00019 20.6 1.0 0.00019 20.6 1.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KXZ44018.1 - 0.00027 19.8 2.4 0.00035 19.4 2.4 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXZ44018.1 - 0.0012 19.4 1.8 0.0018 18.8 1.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ44018.1 - 0.0047 16.2 2.3 0.0062 15.8 2.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXZ44018.1 - 0.019 14.3 2.1 0.027 13.8 2.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXZ44018.1 - 0.019 14.6 0.3 0.026 14.1 0.3 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KXZ44018.1 - 0.019 15.4 1.6 0.028 14.9 1.6 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KXZ44018.1 - 0.025 13.5 1.7 0.03 13.2 1.7 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.24 KXZ44018.1 - 0.048 13.0 0.2 0.07 12.4 0.2 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 KXZ44018.1 - 0.082 13.2 1.5 0.15 12.3 1.5 1.5 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KXZ44018.1 - 0.09 12.7 5.6 0.13 12.1 5.0 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KXZ44018.1 - 0.12 12.1 1.2 0.18 11.5 1.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1188 PF06690.11 KXZ44018.1 - 0.14 11.6 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Shikimate_DH PF01488.20 KXZ44018.1 - 0.2 11.7 0.1 0.28 11.2 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rieske PF00355.26 KXZ44019.1 - 9.7e-13 47.9 0.8 2.1e-12 46.8 0.8 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.24 KXZ44019.1 - 1.2e-09 38.3 3.5 9.9e-09 35.2 3.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase TPR_12 PF13424.6 KXZ44020.1 - 1.4e-48 163.0 23.2 1.3e-14 54.3 4.1 6.8 2 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ44020.1 - 1.8e-33 113.5 34.7 8.9e-07 28.6 0.1 8.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ44020.1 - 4e-09 35.9 20.6 0.095 12.9 0.1 9.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ44020.1 - 1.2e-08 35.4 45.3 0.019 15.6 0.1 9.9 7 1 3 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ44020.1 - 5.9e-06 25.9 10.2 0.89 9.5 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ44020.1 - 0.00035 20.4 10.7 0.98 9.6 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_5 PF12688.7 KXZ44020.1 - 0.0035 17.6 0.6 0.0035 17.6 0.6 3.9 4 0 0 4 4 4 1 Tetratrico peptide repeat TPR_6 PF13174.6 KXZ44020.1 - 0.021 15.4 15.9 31 5.5 0.0 8.7 8 1 1 9 9 9 0 Tetratricopeptide repeat AAA_25 PF13481.6 KXZ44020.1 - 0.047 13.3 1.6 0.18 11.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain TPR_19 PF14559.6 KXZ44020.1 - 0.058 13.9 25.4 0.66 10.5 2.4 6.6 4 1 2 7 7 7 0 Tetratricopeptide repeat BHD_3 PF10405.9 KXZ44021.1 - 7.2e-16 58.4 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 KXZ44021.1 - 1.1e-14 55.1 0.1 7.6e-14 52.4 0.1 2.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 KXZ44021.1 - 8.4e-12 45.0 0.1 1.5e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KXZ44021.1 - 1.3e-10 40.9 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 KXZ44021.1 - 0.022 15.2 1.3 7.5 7.0 0.2 2.8 2 0 0 2 2 2 0 Transglutaminase-like superfamily IlvB_leader PF08049.11 KXZ44023.1 - 0.0085 16.0 0.2 2.3 8.2 0.2 3.7 4 0 0 4 4 4 1 IlvB leader peptide YacG PF03884.14 KXZ44023.1 - 0.13 12.0 0.0 23 4.8 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG ADK PF00406.22 KXZ44024.1 - 2.1e-56 190.2 0.0 3.4e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXZ44024.1 - 2.7e-22 79.7 0.5 1.2e-21 77.6 0.0 2.2 3 0 0 3 3 3 1 AAA domain ADK_lid PF05191.14 KXZ44024.1 - 1.5e-15 56.9 0.0 2.7e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KXZ44024.1 - 0.00026 21.2 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 KXZ44024.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.15 KXZ44024.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KXZ44024.1 - 0.18 12.3 0.3 0.38 11.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain CobT PF06213.12 KXZ44025.1 - 0.067 12.6 2.0 0.14 11.6 2.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FSIP1 PF15554.6 KXZ44025.1 - 0.39 9.8 1.7 0.55 9.3 1.7 1.1 1 0 0 1 1 1 0 FSIP1 family CDC45 PF02724.14 KXZ44025.1 - 4.5 5.5 3.9 6.4 4.9 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KXZ44025.1 - 9.4 4.2 10.5 13 3.7 10.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Abhydrolase_6 PF12697.7 KXZ44026.1 - 1.1e-17 65.4 1.6 1.1e-17 65.4 1.6 3.5 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ44026.1 - 6.6e-13 48.9 0.0 9.2e-12 45.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ44026.1 - 3.4e-09 36.3 0.0 1.7e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 IF-2B PF01008.17 KXZ44027.1 - 9.8e-79 264.5 0.0 1.3e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Thioredoxin_15 PF18403.1 KXZ44027.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain NDK PF00334.19 KXZ44028.1 - 5.4e-69 230.4 0.0 6.9e-42 142.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase zf-CHCC PF10276.9 KXZ44029.1 - 0.0034 17.4 0.4 0.0034 17.4 0.4 1.7 2 0 0 2 2 2 1 Zinc-finger domain RecO_C PF02565.15 KXZ44029.1 - 0.056 13.2 0.5 0.078 12.8 0.5 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal Ferric_reduct PF01794.19 KXZ44029.1 - 0.15 12.2 0.1 0.26 11.4 0.1 1.3 2 0 0 2 2 2 0 Ferric reductase like transmembrane component HMG_box_2 PF09011.10 KXZ44032.1 - 1.4e-14 54.4 1.3 7.7e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KXZ44032.1 - 9.9e-13 48.3 3.9 3.1e-09 37.1 0.0 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box LAX PF15681.5 KXZ44032.1 - 8.9 5.0 6.1 21 3.8 6.1 1.6 1 0 0 1 1 1 0 Lymphocyte activation family X LRR_4 PF12799.7 KXZ44033.1 - 0.00039 20.8 0.1 11 6.6 0.1 4.6 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ44033.1 - 0.0018 18.6 7.6 12 6.9 0.3 6.1 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 KXZ44033.1 - 0.004 17.1 9.5 12 6.2 0.2 7.1 7 0 0 7 7 7 1 Leucine Rich repeat HHH_2 PF12826.7 KXZ44033.1 - 0.077 13.1 0.0 0.84 9.8 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 KXZ44033.1 - 0.099 13.0 0.0 18 5.9 0.0 3.0 2 0 0 2 2 2 0 IMS family HHH motif PNISR PF15996.5 KXZ44033.1 - 2 8.6 6.6 3.4 7.9 6.6 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR ClpS PF02617.17 KXZ44034.1 - 8.7e-05 22.2 0.2 0.00013 21.7 0.2 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS 5_nucleotid PF05761.14 KXZ44035.1 - 9.7 5.0 10.1 0.24 10.3 2.4 1.9 2 0 0 2 2 2 0 5' nucleotidase family 14-3-3 PF00244.20 KXZ44036.1 - 5.5e-105 349.8 3.3 6.3e-105 349.6 3.3 1.0 1 0 0 1 1 1 1 14-3-3 protein PhoU_div PF01865.16 KXZ44036.1 - 0.034 13.5 2.8 0.15 11.3 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF47 TPR_19 PF14559.6 KXZ44036.1 - 0.47 11.0 0.1 0.47 11.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Arm PF00514.23 KXZ44037.1 - 8.4e-05 22.5 27.2 0.048 13.7 0.0 8.4 9 2 0 9 9 9 3 Armadillo/beta-catenin-like repeat KAP PF05804.12 KXZ44037.1 - 0.0003 19.1 0.0 0.11 10.7 0.0 2.3 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 KXZ44037.1 - 0.0036 15.9 0.3 0.046 12.3 0.0 2.1 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_EZ PF13513.6 KXZ44037.1 - 0.039 14.5 0.0 0.039 14.5 0.0 4.9 5 1 1 6 6 6 0 HEAT-like repeat adh_short PF00106.25 KXZ44038.1 - 6.6e-36 123.6 3.1 1.9e-17 63.3 1.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ44038.1 - 1.8e-24 86.6 1.8 3e-12 46.6 1.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KXZ44038.1 - 0.005 16.4 0.1 0.008 15.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KXZ44038.1 - 0.0078 16.1 0.4 0.017 15.1 0.4 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXZ44038.1 - 0.016 15.1 0.3 0.027 14.3 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KXZ44038.1 - 0.016 14.7 0.1 0.066 12.7 0.2 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 KXZ44038.1 - 0.066 13.3 1.0 0.1 12.7 1.0 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain dsDNA_bind PF01984.20 KXZ44039.1 - 4.4e-26 91.3 1.2 5.4e-26 91.1 1.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Linker_histone PF00538.19 KXZ44039.1 - 0.18 12.2 0.5 21 5.6 0.0 2.5 1 1 0 2 2 2 0 linker histone H1 and H5 family zf-MYND PF01753.18 KXZ44040.1 - 4.2e-05 23.6 14.6 0.0001 22.3 14.6 1.8 1 1 0 1 1 1 1 MYND finger DAGAT PF03982.13 KXZ44041.1 - 2.3e-77 259.8 0.0 2.7e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase HAGH_C PF16123.5 KXZ44042.1 - 1e-26 93.2 0.0 1.5e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KXZ44042.1 - 1.2e-15 58.0 0.7 8.5e-15 55.3 0.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXZ44042.1 - 0.016 14.8 0.2 0.027 14.0 0.2 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain IQ PF00612.27 KXZ44043.1 - 2.9e-13 48.4 28.7 4.2e-06 26.1 0.5 5.2 4 0 0 4 4 4 4 IQ calmodulin-binding motif EBP PF05241.12 KXZ44044.1 - 1.4e-39 135.4 12.9 4.4e-36 124.0 4.5 2.0 1 1 1 2 2 2 2 Emopamil binding protein DnaJ PF00226.31 KXZ44045.1 - 2.2e-13 50.1 0.1 5.7e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain HD PF01966.22 KXZ44045.1 - 0.0041 17.3 1.4 0.0073 16.5 1.4 1.4 1 0 0 1 1 1 1 HD domain Phage_DsbA PF11126.8 KXZ44045.1 - 1.7 8.9 7.5 0.094 12.9 1.5 2.1 2 0 0 2 2 2 0 Transcriptional regulator DsbA PrmA PF06325.13 KXZ44046.1 - 1.7e-12 47.4 0.1 2.3e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXZ44046.1 - 3.2e-10 40.6 0.0 7.3e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44046.1 - 1.5e-08 35.2 0.0 3.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ44046.1 - 5.5e-08 32.7 0.0 9.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KXZ44046.1 - 8e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 KXZ44046.1 - 1.2e-05 25.2 0.1 1.8e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KXZ44046.1 - 1.2e-05 24.9 0.1 2.1e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXZ44046.1 - 5.9e-05 23.0 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXZ44046.1 - 7.9e-05 22.6 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXZ44046.1 - 0.00019 20.9 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KXZ44046.1 - 0.00046 19.2 0.0 0.0011 18.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 KXZ44046.1 - 0.0037 16.7 0.3 0.01 15.3 0.0 1.7 2 0 0 2 2 2 1 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 KXZ44046.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 KXZ44046.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 KXZ44046.1 - 0.021 15.9 0.0 0.059 14.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain GidB PF02527.15 KXZ44046.1 - 0.04 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PCMT PF01135.19 KXZ44046.1 - 0.041 13.6 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5_C PF17286.2 KXZ44046.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_12 PF08242.12 KXZ44046.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Synaptobrevin PF00957.21 KXZ44048.1 - 1.3e-09 37.7 1.0 2e-09 37.1 1.0 1.3 1 0 0 1 1 1 1 Synaptobrevin WD40 PF00400.32 KXZ44048.1 - 0.091 13.7 2.7 24 6.0 0.2 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KXZ44049.1 - 2.2e-28 99.2 0.0 2.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ44049.1 - 2.4e-25 89.4 0.0 3.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ44049.1 - 0.3 9.8 0.0 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase TGT PF01702.18 KXZ44050.1 - 3.4e-133 444.2 0.0 1.3e-132 442.3 0.0 1.7 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Spermine_synth PF01564.17 KXZ44051.1 - 1.8e-59 200.3 0.0 2.7e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KXZ44051.1 - 6.6e-22 77.2 0.0 1.1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KXZ44051.1 - 8.7e-05 23.2 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ44051.1 - 0.028 14.2 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KXZ44051.1 - 0.079 14.0 0.0 0.17 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UvrD-helicase PF00580.21 KXZ44052.1 - 2.5e-43 148.8 0.0 6e-32 111.4 0.0 2.8 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KXZ44052.1 - 6.4e-35 121.1 0.0 5.7e-19 68.7 0.0 3.1 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXZ44052.1 - 2.5e-17 63.6 0.0 1.9e-15 57.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXZ44052.1 - 1.7e-11 43.7 1.9 0.00012 21.8 0.0 3.4 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXZ44052.1 - 0.0041 16.8 10.5 0.064 13.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain PhoH PF02562.16 KXZ44052.1 - 0.0056 16.2 0.1 1.8 7.9 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein CENP-B_dimeris PF09026.10 KXZ44052.1 - 2.1 8.8 9.8 5.5 7.5 9.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RIFIN PF02009.16 KXZ44053.1 - 0.24 11.3 7.4 0.5 10.2 7.4 1.5 1 0 0 1 1 1 0 Rifin DDHD PF02862.17 KXZ44053.1 - 0.77 9.9 8.4 1.4 9.0 8.4 1.4 1 0 0 1 1 1 0 DDHD domain SMYLE_N PF18615.1 KXZ44053.1 - 1.8 8.1 9.4 3.2 7.2 9.4 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Pkinase PF00069.25 KXZ44054.1 - 3.7e-31 108.5 0.0 9.6e-17 61.2 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44054.1 - 1.6e-12 47.3 0.0 0.0001 21.7 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase cNMP_binding PF00027.29 KXZ44055.1 - 2.5e-07 30.7 0.0 0.00015 21.8 0.0 3.0 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 KXZ44056.1 - 2.8e-29 102.3 0.0 3.5e-25 88.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44056.1 - 9.4e-28 97.2 0.0 5.3e-26 91.5 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 KXZ44056.1 - 0.00019 21.4 0.4 0.0017 18.3 0.2 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ44056.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXZ44056.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LIME1 PF15332.6 KXZ44056.1 - 3.5 7.2 5.9 8.7 5.9 0.1 2.5 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 Ribosomal_L34 PF00468.17 KXZ44057.1 - 1.9e-15 56.6 7.0 3.5e-15 55.7 7.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 SEA PF01390.20 KXZ44057.1 - 0.028 14.5 0.0 0.036 14.1 0.0 1.1 1 0 0 1 1 1 0 SEA domain DNA_photolyase PF00875.18 KXZ44058.1 - 3.1e-11 43.6 0.0 3.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 DNA photolyase Pkinase_Tyr PF07714.17 KXZ44060.1 - 5.1e-35 121.0 0.0 6.1e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ44060.1 - 1.1e-28 100.4 0.0 1.8e-28 99.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ44060.1 - 1.1e-06 27.7 0.0 1.4e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ44060.1 - 0.004 17.1 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ44060.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ44060.1 - 0.052 12.9 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like PUB PF09409.10 KXZ44062.1 - 1.1e-21 76.6 0.0 6.1e-21 74.2 0.0 2.2 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 KXZ44062.1 - 0.00079 19.3 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Caldesmon PF02029.15 KXZ44062.1 - 0.012 14.4 39.1 0.017 13.9 39.1 1.1 1 0 0 1 1 1 0 Caldesmon zf-C2H2_2 PF12756.7 KXZ44062.1 - 0.1 12.9 2.4 5 7.5 0.0 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MCM3AP_GANP PF16769.5 KXZ44062.1 - 0.8 7.9 12.3 1.1 7.4 12.3 1.3 1 0 0 1 1 1 0 MCM3AP domain of GANP Guanylate_cyc PF00211.20 KXZ44063.1 - 1.4e-44 151.9 0.0 2.4e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain UCH PF00443.29 KXZ44063.1 - 3.1e-43 148.1 0.0 9.2e-43 146.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ44063.1 - 2.6e-17 63.4 0.0 1.6e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KXZ44063.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family UIM PF02809.20 KXZ44063.1 - 0.015 15.1 12.7 0.37 10.8 1.6 4.0 3 0 0 3 3 3 0 Ubiquitin interaction motif Pkinase PF00069.25 KXZ44065.1 - 4.9e-14 52.3 0.0 5.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44065.1 - 5.8e-11 42.2 0.0 6.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ44065.1 - 8.9e-05 22.5 0.0 9.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ44065.1 - 0.077 11.8 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ44065.1 - 0.18 11.1 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXZ44065.1 - 0.22 10.5 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KXZ44067.1 - 2.1e-46 158.3 0.0 9.5e-43 146.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ44067.1 - 8.7e-46 156.4 0.0 6e-44 150.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ44067.1 - 0.0041 17.1 0.1 0.012 15.6 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ44067.1 - 0.0056 15.5 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RcbX PF02341.15 KXZ44068.1 - 0.0059 16.9 0.3 0.0064 16.7 0.3 1.1 1 0 0 1 1 1 1 RbcX protein CRT-like PF08627.10 KXZ44069.1 - 8.5e-26 90.7 2.6 3e-25 88.9 2.6 1.8 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KXZ44069.1 - 0.00085 19.5 4.4 0.00085 19.5 4.4 3.4 2 2 1 3 3 3 1 EamA-like transporter family UAA PF08449.11 KXZ44069.1 - 0.0053 16.0 1.0 0.0097 15.1 1.0 1.4 1 0 0 1 1 1 1 UAA transporter family Tox-MPTase5 PF15641.6 KXZ44069.1 - 0.19 11.8 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Metallopeptidase toxin 5 Inositol_P PF00459.25 KXZ44070.1 - 7.4e-46 156.8 0.0 9.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family AMH_N PF04709.12 KXZ44070.1 - 0.086 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Pkinase_Tyr PF07714.17 KXZ44071.1 - 2.2e-35 122.2 0.0 1.2e-16 60.8 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ44071.1 - 2.1e-32 112.5 0.0 5.4e-29 101.4 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain APH PF01636.23 KXZ44071.1 - 0.0047 16.9 0.3 0.0047 16.9 0.3 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family CGI-121 PF08617.10 KXZ44072.1 - 1.7e-31 109.5 0.0 2e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 AMP-binding PF00501.28 KXZ44073.1 - 8.4e-52 176.2 8.9 4e-48 164.1 7.4 2.9 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ44073.1 - 1.1e-10 42.3 0.0 3.5e-09 37.5 0.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Proteasome PF00227.26 KXZ44074.1 - 2.7e-59 199.8 0.2 3.7e-59 199.4 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXZ44074.1 - 3.9e-14 52.0 0.1 7.1e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PCI PF01399.27 KXZ44075.1 - 1.6e-25 89.6 0.4 4.7e-25 88.1 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.6 KXZ44075.1 - 0.0052 17.5 0.9 14 6.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ44075.1 - 0.013 15.5 7.2 28 5.0 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat SNAP PF14938.6 KXZ44075.1 - 0.028 13.8 6.6 0.25 10.7 0.2 3.6 2 2 2 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 KXZ44075.1 - 0.071 13.6 0.0 0.3 11.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat FliS PF02561.14 KXZ44075.1 - 0.15 12.3 3.2 0.23 11.7 0.8 2.6 3 1 0 3 3 3 0 Flagellar protein FliS HEAT PF02985.22 KXZ44076.1 - 0.025 14.8 0.7 0.058 13.7 0.7 1.7 1 0 0 1 1 1 0 HEAT repeat UQ_con PF00179.26 KXZ44079.1 - 7.8e-36 122.8 0.1 9.8e-36 122.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXZ44079.1 - 0.081 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain Exostosin PF03016.15 KXZ44080.1 - 2.4e-21 76.2 0.3 7e-11 41.9 0.0 2.2 1 1 1 2 2 2 2 Exostosin family EGF_2 PF07974.13 KXZ44080.1 - 0.00028 21.2 14.5 0.00028 21.2 14.5 2.6 2 0 0 2 2 2 1 EGF-like domain EGF PF00008.27 KXZ44080.1 - 2.6 8.4 15.1 0.11 12.8 8.0 2.4 2 0 0 2 2 2 0 EGF-like domain DEAD PF00270.29 KXZ44081.1 - 1.4e-21 77.1 0.0 2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ44081.1 - 1.7e-10 41.2 0.0 2.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S24 PF00717.23 KXZ44081.1 - 1.4e-09 37.8 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like IstB_IS21 PF01695.17 KXZ44081.1 - 6.8e-06 25.9 0.0 0.00048 19.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 KXZ44081.1 - 1.4e-05 24.9 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ44081.1 - 0.00036 20.8 0.1 0.0026 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KXZ44081.1 - 0.00095 18.7 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 KXZ44081.1 - 0.01 15.4 0.7 0.031 13.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXZ44081.1 - 0.037 14.4 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KXZ44081.1 - 0.065 13.6 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_S26 PF10502.9 KXZ44081.1 - 0.18 11.6 0.0 0.81 9.5 0.0 2.1 2 1 0 2 2 2 0 Signal peptidase, peptidase S26 ATPase_2 PF01637.18 KXZ44081.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KXZ44081.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KXZ44081.1 - 0.26 11.8 0.0 0.42 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DSHCT PF08148.12 KXZ44082.1 - 1.1e-27 96.8 0.5 2e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain FoP_duplication PF13865.6 KXZ44082.1 - 0.014 15.9 0.2 0.014 15.9 0.2 1.8 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 kleA_kleC PF17383.2 KXZ44082.1 - 0.074 13.4 7.8 0.1 13.0 5.5 2.3 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A DUF4826 PF16108.5 KXZ44082.1 - 1.5 9.1 6.2 13 6.0 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4826) AAA PF00004.29 KXZ44083.1 - 2.6e-42 144.4 0.0 4.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ44083.1 - 1.5e-13 50.3 0.2 3.2e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KXZ44083.1 - 3.8e-07 30.0 0.3 8.2e-07 28.9 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KXZ44083.1 - 5.2e-07 29.9 0.0 1.9e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXZ44083.1 - 5.2e-06 26.5 0.0 1.9e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ44083.1 - 8e-06 26.3 0.1 0.00011 22.7 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXZ44083.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ44083.1 - 0.00028 21.2 1.1 0.008 16.5 0.2 2.6 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 KXZ44083.1 - 0.00093 18.5 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KXZ44083.1 - 0.001 19.3 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXZ44083.1 - 0.003 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KXZ44083.1 - 0.0042 16.6 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.6 KXZ44083.1 - 0.0044 17.6 0.4 0.021 15.4 0.0 2.2 2 2 0 2 2 1 1 AAA domain AAA_3 PF07726.11 KXZ44083.1 - 0.0069 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXZ44083.1 - 0.0082 15.5 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXZ44083.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RILP PF11461.8 KXZ44083.1 - 0.015 15.5 1.6 0.036 14.3 1.6 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein TsaE PF02367.17 KXZ44083.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2072 PF09845.9 KXZ44083.1 - 0.02 15.1 0.7 0.051 13.8 0.7 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_24 PF13479.6 KXZ44083.1 - 0.021 14.6 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXZ44083.1 - 0.024 15.0 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 KXZ44083.1 - 0.024 14.0 0.0 0.059 12.7 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KXZ44083.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Prot_ATP_OB_N PF17758.1 KXZ44083.1 - 0.036 13.7 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain MscS_porin PF12795.7 KXZ44083.1 - 0.038 13.6 3.8 0.068 12.7 3.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Sigma54_activat PF00158.26 KXZ44083.1 - 0.039 13.6 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KXZ44083.1 - 0.044 12.9 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 KXZ44083.1 - 0.048 13.4 0.2 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KXZ44083.1 - 0.049 12.7 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 KXZ44083.1 - 0.054 13.9 0.5 0.32 11.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KXZ44083.1 - 0.061 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXZ44083.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 KXZ44083.1 - 0.083 13.4 3.3 0.18 12.3 3.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Zeta_toxin PF06414.12 KXZ44083.1 - 0.094 12.0 0.2 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 KXZ44083.1 - 0.11 13.0 0.1 0.62 10.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KLRAQ PF10205.9 KXZ44083.1 - 0.36 11.1 4.3 0.99 9.7 0.4 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 KXZ44083.1 - 0.91 10.0 6.7 1 9.8 4.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HYR PF02494.16 KXZ44084.1 - 2.9e-25 88.4 30.4 1.1e-05 25.7 0.2 8.6 7 1 0 8 8 8 6 HYR domain PAN_4 PF14295.6 KXZ44084.1 - 7.6e-10 38.6 20.7 0.0063 16.4 0.2 5.9 5 0 0 5 5 5 4 PAN domain EGF_3 PF12947.7 KXZ44084.1 - 1.2e-08 35.0 99.4 0.017 15.3 4.0 14.7 12 1 1 13 13 13 9 EGF domain ARL2_Bind_BART PF11527.8 KXZ44085.1 - 4.2e-09 36.5 0.5 5.1e-09 36.2 0.5 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Ribosomal_L5_C PF00673.21 KXZ44086.1 - 9.8e-21 73.7 0.0 1.6e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXZ44086.1 - 7e-17 61.5 0.1 1.3e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 KXZ44086.1 - 0.18 11.6 0.2 0.4 10.4 0.1 1.6 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain FAD_binding_3 PF01494.19 KXZ44087.1 - 6.3e-14 52.0 0.8 1.1e-12 47.9 0.8 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXZ44087.1 - 1.3e-07 31.7 0.0 6.5e-07 29.5 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ44087.1 - 3.6e-06 26.4 0.0 7.5e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ44087.1 - 8e-06 25.3 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXZ44087.1 - 0.00072 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXZ44087.1 - 0.00076 18.8 0.0 0.0018 17.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ44087.1 - 0.001 17.9 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXZ44087.1 - 0.0062 17.1 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXZ44087.1 - 0.014 15.3 0.0 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXZ44087.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4140 PF13600.6 KXZ44087.1 - 4.7 7.7 8.2 20 5.7 5.0 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bromodomain PF00439.25 KXZ44089.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain DDT PF02791.17 KXZ44090.1 - 1e-10 41.7 0.5 2.4e-10 40.6 0.5 1.6 1 0 0 1 1 1 1 DDT domain Acyltransferase PF01553.21 KXZ44091.1 - 1.8e-27 95.6 0.0 2.7e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Viral_NABP PF05515.11 KXZ44091.1 - 0.019 14.8 0.1 0.039 13.8 0.1 1.5 2 0 0 2 2 2 0 Viral nucleic acid binding RicinB_lectin_2 PF14200.6 KXZ44092.1 - 3.3e-18 66.2 5.7 6.1e-13 49.3 0.5 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ44092.1 - 3.4e-16 59.6 0.7 6.9e-16 58.7 0.7 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KXZ44092.1 - 6e-08 32.4 0.5 7.4e-08 32.1 0.5 1.2 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain Pkinase PF00069.25 KXZ44093.1 - 7.3e-06 25.5 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Synaptonemal_3 PF15191.6 KXZ44093.1 - 0.025 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Pkinase_Tyr PF07714.17 KXZ44093.1 - 0.034 13.4 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase OmpH PF03938.14 KXZ44093.1 - 0.043 14.1 1.0 0.07 13.5 1.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) T3SS_needle_F PF09392.10 KXZ44093.1 - 0.06 13.5 0.2 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF COG6 PF06419.11 KXZ44093.1 - 0.064 11.5 1.8 0.088 11.0 1.8 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF5529 PF17669.1 KXZ44093.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5529) DivIC PF04977.15 KXZ44093.1 - 1.1 9.0 6.0 1.8 8.4 0.6 2.3 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 KXZ44093.1 - 1.7 9.1 6.2 1.6 9.3 4.6 1.8 1 1 1 2 2 2 0 Cell division protein ZapB FlgN PF05130.12 KXZ44093.1 - 3.1 8.3 7.5 16 6.0 3.7 2.6 2 1 0 2 2 2 0 FlgN protein RicinB_lectin_2 PF14200.6 KXZ44094.1 - 1.7e-13 51.1 3.7 5.3e-08 33.5 0.4 3.3 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ44094.1 - 6.9e-11 42.5 0.5 9.8e-08 32.3 0.2 3.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KXZ44094.1 - 0.0019 17.8 0.4 0.079 12.5 0.1 2.5 1 1 2 3 3 3 1 Cytolethal distending toxin A/C domain VOMI PF03762.17 KXZ44094.1 - 0.016 15.3 0.1 0.034 14.3 0.1 1.6 1 1 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) SpoU_methylase PF00588.19 KXZ44095.1 - 6.6e-26 91.2 0.1 1.5e-25 90.0 0.0 1.7 2 0 0 2 2 2 1 SpoU rRNA Methylase family BLUF PF04940.12 KXZ44096.1 - 1.8 8.8 7.7 0.61 10.3 0.6 2.7 2 0 0 2 2 2 0 Sensors of blue-light using FAD PKcGMP_CC PF16808.5 KXZ44096.1 - 9.3 6.2 17.5 3.2 7.7 0.1 6.0 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NFACT-C PF11923.8 KXZ44097.1 - 0.061 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain Thioredoxin PF00085.20 KXZ44098.1 - 0.00077 19.4 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin SPRY PF00622.28 KXZ44099.1 - 0.0015 18.6 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain DUF1279 PF06916.13 KXZ44100.1 - 1.9e-14 54.0 0.0 2.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Pkinase PF00069.25 KXZ44101.1 - 2.5e-18 66.4 0.0 3.6e-08 33.1 0.0 3.3 2 2 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44101.1 - 1.9e-15 56.9 0.0 6.9e-08 32.1 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 KXZ44101.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KXZ44101.1 - 0.012 14.5 0.1 0.017 13.9 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase RuvC PF02075.17 KXZ44101.1 - 0.089 12.7 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC APH PF01636.23 KXZ44101.1 - 7.2 6.5 10.2 1.3 8.9 6.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family PAS PF00989.25 KXZ44102.1 - 1.1e-06 28.6 0.0 0.051 13.6 0.0 4.2 5 0 0 5 5 5 2 PAS fold PAS_4 PF08448.10 KXZ44102.1 - 7.5e-06 26.2 2.1 0.018 15.3 0.0 5.6 5 1 0 5 5 5 1 PAS fold PAS_9 PF13426.7 KXZ44102.1 - 1.6e-05 25.1 0.0 0.0038 17.5 0.0 4.1 6 0 0 6 6 6 1 PAS domain PAS_8 PF13188.7 KXZ44102.1 - 0.0026 17.7 0.0 0.086 12.9 0.0 2.7 2 0 0 2 2 2 1 PAS domain P22_AR_C PF10548.9 KXZ44102.1 - 0.18 12.0 1.3 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 P22AR C-terminal domain XPC-binding PF09280.11 KXZ44103.1 - 0.0042 16.8 9.1 0.38 10.5 0.9 2.8 2 0 0 2 2 2 2 XPC-binding domain Ank_2 PF12796.7 KXZ44104.1 - 4.5e-09 36.8 0.0 0.082 13.5 0.0 4.3 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44104.1 - 6.4e-09 36.2 5.8 0.1 13.2 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44104.1 - 2.2 8.7 4.5 2.7e+02 2.1 0.0 4.9 3 2 3 6 6 6 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ44105.1 - 1.6e-16 60.4 1.5 0.0015 19.1 0.0 6.8 5 2 3 8 8 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44105.1 - 5.9e-12 46.0 0.2 0.033 14.8 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44105.1 - 1.2e-07 31.4 1.8 0.54 11.0 0.0 7.9 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ44105.1 - 0.0029 17.9 3.5 16 5.9 0.0 5.7 5 2 2 7 7 7 1 Ankyrin repeats (many copies) DUF4224 PF13986.6 KXZ44105.1 - 1 9.3 3.4 19 5.2 0.1 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4224) Xan_ur_permease PF00860.20 KXZ44106.1 - 5e-61 206.5 29.8 3.6e-39 134.6 15.6 2.2 2 0 0 2 2 2 2 Permease family MFS_MOT1 PF16983.5 KXZ44106.1 - 1.5 9.2 16.3 7.1 7.1 4.5 3.2 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily HisKA_4TM PF16926.5 KXZ44107.1 - 0.075 12.6 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase VCBS PF13517.6 KXZ44108.1 - 8.7e-05 23.0 1.5 11 6.7 0.0 4.4 4 0 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_1 PF00036.32 KXZ44108.1 - 0.00027 20.3 3.7 4.4 7.1 0.0 4.0 4 0 0 4 4 4 3 EF hand DUF1883 PF08980.10 KXZ44108.1 - 0.018 15.0 0.2 79 3.3 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1883) EF-hand_6 PF13405.6 KXZ44108.1 - 4.6 7.4 6.8 47 4.3 0.1 3.8 4 0 0 4 4 4 0 EF-hand domain Ank_5 PF13857.6 KXZ44109.1 - 7.6e-12 45.2 1.0 2.9e-05 24.2 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44109.1 - 1.3e-09 38.1 3.6 4.5e-05 23.7 0.7 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KXZ44109.1 - 2.2e-08 34.6 0.0 1.4e-05 25.6 0.1 3.5 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44109.1 - 1.6e-06 28.5 0.6 0.019 15.6 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44109.1 - 6.4e-06 26.1 1.5 0.016 15.7 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat PAS_8 PF13188.7 KXZ44110.1 - 7.3e-05 22.7 0.0 0.18 11.9 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KXZ44110.1 - 0.00019 21.4 0.0 0.23 11.5 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 KXZ44110.1 - 0.00074 19.7 0.0 0.0062 16.8 0.0 2.5 4 0 0 4 4 4 1 PAS domain PAS_4 PF08448.10 KXZ44110.1 - 0.0013 18.9 0.3 2.5 8.4 0.0 4.3 5 0 0 5 5 5 1 PAS fold PAS_7 PF12860.7 KXZ44110.1 - 0.028 14.6 0.0 0.19 11.9 0.0 2.4 3 0 0 3 3 3 0 PAS fold p450 PF00067.22 KXZ44112.1 - 1.9e-87 293.9 0.0 2.5e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 KXZ44113.1 - 3.4e-27 95.2 0.0 4.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M90 PF06167.12 KXZ44114.1 - 0.18 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 CCDC144C PF14915.6 KXZ44115.1 - 0.026 13.7 0.2 0.037 13.1 0.2 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Prefoldin_2 PF01920.20 KXZ44115.1 - 0.047 13.7 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit Lzipper-MIP1 PF14389.6 KXZ44115.1 - 0.061 13.6 1.0 0.11 12.8 0.7 1.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Dam PF05869.11 KXZ44117.1 - 6.4e-09 35.6 0.0 8.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) DUF1757 PF08560.10 KXZ44118.1 - 7.6e-08 32.5 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) NADH-u_ox-rdase PF10785.9 KXZ44118.1 - 0.35 11.6 2.7 6.9 7.4 2.7 2.6 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4781 PF16013.5 KXZ44118.1 - 0.86 8.4 4.3 0.23 10.2 1.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Hint PF01079.20 KXZ44119.1 - 1.9e-38 132.2 0.0 2.9e-38 131.5 0.0 1.4 1 1 0 1 1 1 1 Hint module Alpha_E2_glycop PF00943.19 KXZ44119.1 - 0.012 14.3 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein DHQS PF01959.16 KXZ44119.1 - 0.046 12.6 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase II Hint_2 PF13403.6 KXZ44119.1 - 0.078 13.3 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 Hint domain Hint PF01079.20 KXZ44122.1 - 6e-30 104.4 0.0 1.2e-29 103.4 0.0 1.5 1 1 0 1 1 1 1 Hint module Patatin PF01734.22 KXZ44122.1 - 0.05 13.8 0.1 0.094 12.9 0.1 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase ABC2_membrane PF01061.24 KXZ44123.1 - 4.2e-06 26.3 8.9 5.6e-06 25.9 8.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ44124.1 - 4.8e-18 66.0 0.0 9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ44124.1 - 1.8e-05 24.8 0.0 0.078 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KXZ44124.1 - 0.0004 20.8 0.0 0.073 13.5 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXZ44124.1 - 0.00059 19.8 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KXZ44124.1 - 0.00059 19.8 0.5 0.0015 18.5 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXZ44124.1 - 0.0053 16.3 0.1 0.0087 15.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KXZ44124.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KXZ44124.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KXZ44124.1 - 0.017 15.6 0.1 0.033 14.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ44124.1 - 0.021 15.3 0.0 0.04 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXZ44124.1 - 0.024 14.4 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KXZ44124.1 - 0.029 13.8 0.3 1.9 7.9 0.1 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KXZ44124.1 - 0.031 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ44124.1 - 0.07 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXZ44124.1 - 0.092 12.5 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXZ44124.1 - 0.093 13.1 0.0 0.25 11.8 0.0 1.6 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.21 KXZ44124.1 - 0.098 12.0 0.6 0.28 10.5 0.2 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXZ44124.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KXZ44124.1 - 0.11 12.6 0.1 0.54 10.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KXZ44124.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KXZ44124.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein MMR_HSR1 PF01926.23 KXZ44124.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ank_2 PF12796.7 KXZ44125.1 - 3.8e-14 53.0 0.0 0.027 15.0 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44125.1 - 5.1e-13 49.3 6.5 0.0024 18.4 0.0 6.7 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44125.1 - 1e-06 28.6 2.0 0.93 10.3 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat HTH_39 PF14090.6 KXZ44125.1 - 0.0086 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Ad_Cy_reg PF16701.5 KXZ44125.1 - 0.029 14.1 1.1 9.8 5.9 0.0 3.8 4 1 0 4 4 4 0 Adenylate cyclase regulatory domain Ank_5 PF13857.6 KXZ44125.1 - 0.18 12.2 4.3 32 5.0 0.0 5.5 3 2 4 7 7 7 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ44128.1 - 3.7e-09 37.0 1.6 0.00056 20.4 0.0 4.7 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44128.1 - 6.2e-07 29.9 0.2 0.23 12.1 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44128.1 - 0.47 11.0 1.6 4.2 8.0 0.1 3.2 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 KXZ44128.1 - 1.2 9.5 4.2 7.1 7.1 0.0 4.2 5 1 1 6 6 6 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44129.1 - 2.5e-09 37.6 0.1 0.022 15.3 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44129.1 - 1.3e-07 32.1 4.2 0.38 11.4 0.1 5.9 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44129.1 - 0.00025 21.2 1.7 40 5.2 0.0 6.9 7 0 0 7 7 7 1 Ankyrin repeat DUF4407 PF14362.6 KXZ44130.1 - 0.016 14.6 15.0 2.4 7.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) IL11 PF07400.11 KXZ44130.1 - 0.41 10.3 2.5 2.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Interleukin 11 Prefoldin_2 PF01920.20 KXZ44130.1 - 0.72 9.8 15.5 5.6 7.0 1.2 4.0 3 1 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 KXZ44130.1 - 1.5 9.0 9.1 0.58 10.3 1.1 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.21 KXZ44130.1 - 3.7 7.7 6.8 0.89 9.7 1.8 2.5 3 0 0 3 3 3 0 bZIP transcription factor SlyX PF04102.12 KXZ44130.1 - 6.9 7.4 14.0 4 8.1 0.2 4.5 5 0 0 5 5 5 0 SlyX NmrA PF05368.13 KXZ44131.1 - 3.4e-21 75.9 0.0 4.6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXZ44131.1 - 3.8e-20 72.6 0.0 7.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXZ44131.1 - 5.5e-09 35.8 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ44131.1 - 2e-07 30.3 0.0 3.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KXZ44131.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KXZ44131.1 - 0.0088 15.2 0.0 0.082 12.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.18 KXZ44131.1 - 0.017 15.4 0.0 0.049 13.9 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain RmlD_sub_bind PF04321.17 KXZ44131.1 - 0.041 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain EF-hand_6 PF13405.6 KXZ44132.1 - 0.039 13.9 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain REJ PF02010.15 KXZ44133.1 - 4.5e-11 42.2 0.0 3.2e-07 29.5 0.0 3.4 3 0 0 3 3 3 3 REJ domain Podoplanin PF05808.11 KXZ44133.1 - 0.0054 16.8 3.0 0.0054 16.8 3.0 2.6 3 0 0 3 3 3 1 Podoplanin CAP PF00188.26 KXZ44134.1 - 2.6e-20 73.5 5.9 3.3e-20 73.2 5.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Keratin_2_head PF16208.5 KXZ44135.1 - 0.0021 18.2 15.4 0.0049 17.0 7.6 2.1 2 0 0 2 2 2 2 Keratin type II head KRTAP PF11759.8 KXZ44135.1 - 0.051 14.1 9.1 0.051 14.1 9.1 2.0 2 0 0 2 2 2 0 Keratin-associated matrix PUB PF09409.10 KXZ44136.1 - 1.4e-05 25.0 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 KXZ44136.1 - 0.00027 21.1 0.0 0.00039 20.6 0.0 1.3 1 0 0 1 1 1 1 UBX domain DUF1780 PF08682.10 KXZ44136.1 - 0.033 13.9 0.3 0.44 10.2 0.2 2.1 2 0 0 2 2 2 0 Putative endonuclease, protein of unknown function (DUF1780) PAP2 PF01569.21 KXZ44136.1 - 1.1 9.1 5.4 1.8 8.3 5.4 1.3 1 0 0 1 1 1 0 PAP2 superfamily PAP_fibrillin PF04755.12 KXZ44137.1 - 2.2e-12 47.3 0.0 2.7e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 PAP_fibrillin REJ PF02010.15 KXZ44139.1 - 5.8e-11 41.8 0.1 2.7e-10 39.6 0.1 2.1 2 0 0 2 2 2 1 REJ domain Ank_4 PF13637.6 KXZ44140.1 - 1.7e-10 41.2 3.4 1.7 9.4 0.0 8.2 6 3 3 9 9 9 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44140.1 - 1.6e-08 35.0 0.0 0.15 12.7 0.0 4.7 3 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44140.1 - 1.7e-05 24.8 0.9 59 4.7 0.0 8.0 10 0 0 10 10 10 0 Ankyrin repeat QSregVF_b PF12843.7 KXZ44140.1 - 0.014 15.2 0.1 0.085 12.8 0.0 2.3 3 0 0 3 3 3 0 Putative quorum-sensing-regulated virulence factor Ank_5 PF13857.6 KXZ44140.1 - 0.31 11.4 7.4 90 3.6 0.0 6.1 9 0 0 9 9 9 0 Ankyrin repeats (many copies) Arm PF00514.23 KXZ44142.1 - 1.3e-10 41.0 30.0 0.003 17.6 1.3 8.0 9 1 1 10 10 10 5 Armadillo/beta-catenin-like repeat GvpL_GvpF PF06386.11 KXZ44143.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Thermopsin PF05317.11 KXZ44145.1 - 0.086 12.3 0.0 0.098 12.1 0.0 1.0 1 0 0 1 1 1 0 Thermopsin Tricorn_PDZ PF14685.6 KXZ44147.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain RT_RNaseH_2 PF17919.1 KXZ44148.1 - 6.1e-21 74.3 0.2 1.1e-20 73.5 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ44148.1 - 1.3e-10 41.5 0.1 2.9e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ44148.1 - 1.3e-06 28.1 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 KXZ44149.1 - 1.8e-42 145.5 0.0 2e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ44149.1 - 2.2e-41 142.0 0.0 2.4e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ44149.1 - 0.00035 19.5 0.0 0.00047 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ44149.1 - 0.00083 19.3 0.4 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ44149.1 - 0.01 14.8 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ank_2 PF12796.7 KXZ44151.1 - 4.5e-26 91.3 4.6 1.8e-13 50.9 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44151.1 - 7.6e-23 78.1 1.1 0.00027 21.1 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KXZ44151.1 - 2.4e-20 72.0 9.1 0.00024 21.4 0.2 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ44151.1 - 1.9e-18 66.6 0.4 1.6e-09 38.1 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44151.1 - 1.5e-15 57.1 8.8 3.8e-07 30.3 1.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF3368 PF11848.8 KXZ44151.1 - 0.11 12.3 0.2 20 5.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) Calponin PF00402.18 KXZ44151.1 - 0.17 11.5 0.4 29 4.4 0.0 2.6 2 0 0 2 2 2 0 Calponin family repeat UBA PF00627.31 KXZ44151.1 - 0.61 10.1 7.1 30 4.6 0.1 3.8 4 0 0 4 4 4 0 UBA/TS-N domain Pkinase_Tyr PF07714.17 KXZ44152.1 - 1.4e-45 155.6 0.0 5.7e-42 143.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ44152.1 - 3.4e-43 147.9 0.0 1.8e-40 139.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ44152.1 - 0.00038 19.4 0.0 0.00055 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ44152.1 - 0.0018 18.2 0.1 0.0047 16.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ44152.1 - 0.058 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KXZ44153.1 - 1.8e-41 142.2 0.0 3.7e-39 134.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44153.1 - 1.7e-39 135.7 0.0 5.7e-37 127.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ44153.1 - 0.0021 16.9 0.0 0.0029 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ44153.1 - 0.0047 16.9 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ44153.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ank_2 PF12796.7 KXZ44154.1 - 8.6e-33 112.8 9.5 3e-14 53.4 0.7 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44154.1 - 1.8e-31 107.2 17.2 3.9e-06 27.1 0.5 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KXZ44154.1 - 2.1e-28 98.3 9.1 4.8e-10 39.8 0.3 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44154.1 - 3.5e-28 94.5 4.0 7e-05 22.9 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KXZ44154.1 - 1.5e-21 76.1 9.1 1.4e-07 31.6 0.3 4.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44154.1 - 0.0014 18.3 7.9 50 3.7 0.1 5.3 5 0 0 5 5 5 0 Calponin family repeat HTH_16 PF12645.7 KXZ44154.1 - 0.0071 16.4 3.2 28 4.9 0.0 4.1 4 0 0 4 4 4 0 Helix-turn-helix domain Glyoxalase_4 PF13669.6 KXZ44154.1 - 0.35 11.1 3.0 5.5 7.3 0.2 2.4 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UBA PF00627.31 KXZ44154.1 - 7 6.7 14.5 34 4.5 0.2 4.6 5 0 0 5 5 5 0 UBA/TS-N domain Staph_haemo PF05480.11 KXZ44154.1 - 9.6 6.1 19.6 9.9 6.0 0.2 4.9 5 0 0 5 5 5 0 Staphylococcus haemolytic protein Ank_2 PF12796.7 KXZ44155.1 - 2.8e-69 229.7 38.1 5.5e-15 55.7 0.9 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44155.1 - 8.1e-52 167.2 12.0 2.9e-05 24.1 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 KXZ44155.1 - 1.9e-49 165.4 16.4 6.2e-12 45.8 0.1 6.0 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44155.1 - 3.6e-46 153.7 31.3 3.1e-06 27.4 0.1 9.0 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 KXZ44155.1 - 2.7e-31 107.2 22.1 1.4e-07 31.7 0.3 7.6 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44155.1 - 0.0004 20.0 20.6 76 3.1 0.1 9.0 9 0 0 9 9 9 0 Calponin family repeat DUF433 PF04255.14 KXZ44155.1 - 0.00071 19.4 4.1 59 3.6 0.0 7.2 9 0 0 9 9 9 0 Protein of unknown function (DUF433) FemAB_like PF04339.12 KXZ44155.1 - 0.019 14.1 1.1 8.6 5.4 0.1 3.3 1 1 2 3 3 3 0 Peptidogalycan biosysnthesis/recognition HTH_16 PF12645.7 KXZ44155.1 - 0.049 13.7 16.1 43 4.3 0.0 7.1 8 0 0 8 8 8 0 Helix-turn-helix domain Ank_2 PF12796.7 KXZ44156.1 - 1.9e-12 47.6 0.5 2.2e-12 47.4 0.5 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44156.1 - 2.2e-11 43.7 3.5 1.4e-07 31.6 0.3 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXZ44156.1 - 2.9e-11 43.4 3.8 6.5e-06 26.3 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44156.1 - 7.6e-11 41.3 0.3 3.9e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXZ44156.1 - 1.3e-10 41.6 0.2 1.6e-10 41.3 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ACC_epsilon PF13822.6 KXZ44156.1 - 0.013 16.2 1.5 1.2 9.9 0.1 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Calponin PF00402.18 KXZ44156.1 - 0.058 13.0 0.4 14 5.4 0.1 2.5 2 0 0 2 2 2 0 Calponin family repeat Ank_2 PF12796.7 KXZ44157.1 - 2.7e-29 101.6 1.6 8.1e-14 52.0 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44157.1 - 8.7e-27 90.2 0.6 7.9e-05 22.8 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KXZ44157.1 - 4.7e-25 86.9 10.0 1.1e-05 25.6 0.2 5.6 4 1 1 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KXZ44157.1 - 4.6e-24 84.5 3.3 7.1e-11 42.4 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44157.1 - 3.7e-20 71.7 7.5 2.1e-08 34.3 0.1 4.4 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Roc PF08477.13 KXZ44157.1 - 1.3e-19 70.6 0.0 1.9e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ44157.1 - 5e-11 42.5 0.0 7.4e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Ras family COR PF16095.5 KXZ44157.1 - 1.9e-09 37.6 0.0 3.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Arf PF00025.21 KXZ44157.1 - 4.4e-06 26.3 0.0 7.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXZ44157.1 - 0.00042 19.8 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KXZ44157.1 - 0.0026 17.9 0.0 0.0066 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KXZ44157.1 - 0.0057 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 KXZ44157.1 - 0.02 15.1 0.0 0.06 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXZ44157.1 - 0.043 13.9 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXZ44157.1 - 0.048 14.2 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KXZ44157.1 - 0.063 13.7 0.7 0.28 11.6 0.0 2.3 2 1 1 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 KXZ44157.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ank_2 PF12796.7 KXZ44158.1 - 7.9e-24 84.1 0.6 1.7e-15 57.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44158.1 - 1.2e-21 76.1 1.0 2e-06 28.0 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ44158.1 - 2e-20 72.6 3.3 2.3e-07 31.0 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44158.1 - 9.6e-20 68.6 0.1 9.6e-05 22.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXZ44158.1 - 3.7e-18 65.6 0.1 2.7e-10 40.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44158.1 - 0.018 14.6 4.5 22 4.8 0.0 3.8 4 0 0 4 4 4 0 Calponin family repeat DUF4129 PF13559.6 KXZ44158.1 - 0.27 11.5 5.0 3.7 7.9 2.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4129) UBA PF00627.31 KXZ44158.1 - 0.83 9.6 3.4 13 5.8 0.1 3.1 3 0 0 3 3 3 0 UBA/TS-N domain Ank_2 PF12796.7 KXZ44159.1 - 1.5e-154 502.9 56.0 8.9e-19 67.9 4.0 13.0 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44159.1 - 5e-135 438.3 29.5 2.5e-12 47.1 0.0 15.7 10 3 8 18 18 18 17 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44159.1 - 2.4e-126 407.2 90.3 1.7e-06 28.2 0.1 24.9 24 1 1 25 25 25 22 Ankyrin repeat Ank_3 PF13606.6 KXZ44159.1 - 3.5e-123 386.4 38.8 0.00012 22.2 0.0 24.5 24 1 1 25 25 24 21 Ankyrin repeat Ank_5 PF13857.6 KXZ44159.1 - 1.7e-99 324.5 62.6 3.2e-09 36.9 0.3 19.1 7 7 14 21 21 21 21 Ankyrin repeats (many copies) Roc PF08477.13 KXZ44159.1 - 2.5e-18 66.5 0.0 4.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ44159.1 - 6.3e-12 45.4 0.0 1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ44159.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXZ44159.1 - 0.00085 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KXZ44159.1 - 0.0032 18.0 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Mg_chelatase PF01078.21 KXZ44159.1 - 0.0061 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXZ44159.1 - 0.014 15.5 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ44159.1 - 0.018 15.4 0.0 0.073 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KXZ44159.1 - 0.023 13.9 0.1 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain RuvB_N PF05496.12 KXZ44159.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRPRB PF09439.10 KXZ44159.1 - 0.028 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXZ44159.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KXZ44159.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KXZ44159.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KXZ44159.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXZ44159.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXZ44159.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KXZ44159.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KXZ44159.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXZ44159.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4799 PF16056.5 KXZ44159.1 - 6.9 5.7 5.1 18 4.4 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4799) COR PF16095.5 KXZ44160.1 - 3.5e-16 59.6 0.0 5.6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain SAPI PF16560.5 KXZ44160.1 - 0.27 10.8 0.0 0.45 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative mobile pathogenicity island PAP2_3 PF14378.6 KXZ44161.1 - 0.0065 16.2 0.6 1.6 8.4 0.1 2.0 1 1 1 2 2 2 2 PAP2 superfamily Roc PF08477.13 KXZ44162.1 - 1.1e-14 54.7 0.0 1.7e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ44162.1 - 2.1e-12 47.3 0.0 3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 KXZ44162.1 - 5.8e-08 32.5 0.0 9.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ44162.1 - 5.5e-06 26.0 0.0 8.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_25 PF13481.6 KXZ44162.1 - 0.013 15.1 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXZ44162.1 - 0.039 14.1 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ44162.1 - 0.04 14.3 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 KXZ44162.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 KXZ44162.1 - 0.078 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.12 KXZ44162.1 - 0.08 12.3 0.1 0.31 10.3 0.1 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 KXZ44162.1 - 0.099 13.2 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ44162.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KXZ44162.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.13 KXZ44162.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KXZ44162.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein SRPRB PF09439.10 KXZ44162.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KXZ44162.1 - 0.17 11.9 0.4 0.4 10.7 0.4 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ44162.1 - 0.18 12.1 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Acyl-CoA_dh_C PF12806.7 KXZ44163.1 - 0.048 13.8 0.1 0.087 13.0 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Pkinase_Tyr PF07714.17 KXZ44164.1 - 2.3e-17 63.2 0.0 2.7e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ44164.1 - 1.6e-10 40.8 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ABC2_membrane PF01061.24 KXZ44166.1 - 4 6.8 12.3 0.043 13.2 4.4 1.7 2 1 0 2 2 2 0 ABC-2 type transporter Ank_2 PF12796.7 KXZ44167.1 - 1.7e-105 345.8 9.4 2e-16 60.4 0.1 7.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44167.1 - 3.9e-89 281.8 2.1 6.9e-07 29.1 0.0 14.3 14 0 0 14 14 14 14 Ankyrin repeat Ank PF00023.30 KXZ44167.1 - 8.1e-88 285.4 17.4 1.3e-06 28.5 0.1 14.1 14 0 0 14 14 14 14 Ankyrin repeat Ank_4 PF13637.6 KXZ44167.1 - 1.7e-82 270.8 9.2 4.4e-12 46.3 0.0 10.7 4 4 6 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44167.1 - 1.8e-65 216.1 22.3 1.3e-07 31.8 0.0 12.3 1 1 9 12 12 12 12 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44167.1 - 0.0039 16.8 13.4 7.4 6.3 0.0 7.4 8 0 0 8 8 8 1 Calponin family repeat Phage_TTP_1 PF04630.12 KXZ44167.1 - 0.018 14.3 0.0 0.34 10.2 0.0 2.4 1 1 1 2 2 2 0 Phage tail tube protein GATase_7 PF13537.6 KXZ44167.1 - 0.019 14.9 0.0 2.3e+02 1.7 0.0 5.7 4 2 3 7 7 7 0 Glutamine amidotransferase domain NlpE_C PF17185.4 KXZ44167.1 - 0.044 14.1 0.0 2.9 8.2 0.0 3.1 3 0 0 3 3 3 0 NlpE C-terminal OB domain MBT PF02820.18 KXZ44167.1 - 2.1 8.8 6.4 1.9e+02 2.5 0.0 5.2 6 0 0 6 6 6 0 mbt repeat Imm_superinfect PF14373.6 KXZ44167.1 - 9.5 6.2 12.5 1e+02 2.9 0.1 6.4 7 0 0 7 7 7 0 Superinfection immunity protein Roc PF08477.13 KXZ44168.1 - 1.6e-15 57.4 0.0 5.8e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ44168.1 - 1.1e-07 31.6 0.0 4.3e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Ras family COR PF16095.5 KXZ44168.1 - 2.6e-05 24.1 0.0 0.015 15.1 0.0 2.1 1 1 1 2 2 2 2 C-terminal of Roc, COR, domain Arf PF00025.21 KXZ44168.1 - 5.6e-05 22.7 0.0 0.00041 19.9 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_25 PF13481.6 KXZ44168.1 - 0.013 15.1 0.3 0.035 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXZ44168.1 - 0.025 14.7 0.1 0.078 13.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ44168.1 - 0.028 14.7 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXZ44168.1 - 0.032 14.8 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXZ44168.1 - 0.068 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ44168.1 - 0.074 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KXZ44168.1 - 0.086 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KXZ44168.1 - 0.097 11.8 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 KXZ44168.1 - 0.15 11.5 0.2 0.77 9.2 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 KXZ44168.1 - 0.15 11.4 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRPRB PF09439.10 KXZ44168.1 - 0.17 11.3 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXZ44168.1 - 0.21 10.9 0.2 0.84 8.9 0.2 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.14 KXZ44168.1 - 0.21 11.6 0.4 0.38 10.7 0.4 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ank_2 PF12796.7 KXZ44169.1 - 2.5e-38 130.5 6.6 1.6e-14 54.3 0.5 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44169.1 - 3.9e-25 85.2 0.0 0.00016 21.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KXZ44169.1 - 4.5e-25 87.0 4.3 3.2e-07 30.5 0.1 4.1 3 1 1 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ44169.1 - 1e-23 83.4 0.2 1.7e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44169.1 - 8.3e-23 80.2 0.4 5.7e-08 32.9 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) CUE PF02845.16 KXZ44169.1 - 0.11 12.3 0.4 36 4.2 0.1 3.2 4 0 0 4 4 4 0 CUE domain Ank_2 PF12796.7 KXZ44170.1 - 7.5e-78 257.2 21.5 3.2e-13 50.1 0.0 7.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44170.1 - 5.8e-65 213.1 41.2 2e-06 28.0 0.1 13.2 11 2 2 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 KXZ44170.1 - 5.3e-64 204.6 15.9 1.7e-05 24.9 0.1 13.6 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.6 KXZ44170.1 - 8.8e-63 207.9 18.9 2e-10 41.0 0.0 9.1 6 2 5 11 11 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44170.1 - 1.3e-52 175.1 34.6 2.4e-10 40.4 0.2 11.7 4 2 9 13 13 12 11 Ankyrin repeats (many copies) Roc PF08477.13 KXZ44170.1 - 2.3e-19 69.8 0.0 4.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ44170.1 - 1.8e-12 47.2 0.0 2.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ44170.1 - 7.8e-08 32.0 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family COR PF16095.5 KXZ44170.1 - 7.6e-07 29.1 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Gtr1_RagA PF04670.12 KXZ44170.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXZ44170.1 - 0.0073 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 KXZ44170.1 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXZ44170.1 - 0.049 13.7 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase RuvB_N PF05496.12 KXZ44170.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KXZ44170.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KXZ44170.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Calponin PF00402.18 KXZ44170.1 - 6.5 6.5 6.3 1.9e+02 1.8 0.1 4.3 4 0 0 4 4 4 0 Calponin family repeat Ank_2 PF12796.7 KXZ44171.1 - 4e-37 126.7 6.0 3.4e-18 66.0 2.9 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44171.1 - 4e-36 118.9 3.1 5.4e-06 26.4 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KXZ44171.1 - 5.4e-34 115.2 12.9 8.2e-08 32.4 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KXZ44171.1 - 8.3e-31 106.0 5.0 2.8e-12 46.9 0.2 3.8 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44171.1 - 1e-28 99.0 16.1 2.4e-07 30.9 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44171.1 - 0.0055 16.3 4.6 27 4.5 0.1 4.4 4 0 0 4 4 4 0 Calponin family repeat IRK_N PF08466.10 KXZ44171.1 - 0.011 15.9 0.0 45 4.3 0.0 4.4 5 0 0 5 5 5 0 Inward rectifier potassium channel N-terminal HTH_16 PF12645.7 KXZ44171.1 - 0.05 13.6 5.5 33 4.6 0.1 4.4 5 0 0 5 5 5 0 Helix-turn-helix domain La_HTH_kDCL PF18177.1 KXZ44171.1 - 0.11 12.8 0.4 83 3.6 0.0 3.6 3 1 1 4 4 4 0 La HTH in kinetoplastid DICER domain Glyoxalase_4 PF13669.6 KXZ44171.1 - 0.22 11.8 1.8 2.6 8.4 0.2 2.3 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FliT PF05400.13 KXZ44171.1 - 1.4 9.7 7.5 18 6.2 0.3 4.3 3 2 0 3 3 3 0 Flagellar protein FliT Ank_2 PF12796.7 KXZ44173.1 - 1.6e-39 134.4 4.0 1.9e-17 63.6 0.4 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44173.1 - 2.2e-39 133.3 11.4 2.4e-09 37.6 0.1 5.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44173.1 - 2.4e-37 125.8 6.5 5.1e-05 23.5 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KXZ44173.1 - 1.4e-33 111.1 0.5 0.00047 20.4 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KXZ44173.1 - 1.2e-24 86.1 10.2 2.1e-05 24.7 0.1 6.8 2 1 5 7 7 7 6 Ankyrin repeats (many copies) DUF2182 PF09948.9 KXZ44173.1 - 0.026 14.4 0.7 0.94 9.3 0.3 2.3 1 1 1 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) GATase_7 PF13537.6 KXZ44173.1 - 0.033 14.1 0.1 4 7.4 0.0 3.3 2 2 1 3 3 3 0 Glutamine amidotransferase domain Calponin PF00402.18 KXZ44173.1 - 6.5 6.5 5.9 54 3.6 0.0 3.8 5 0 0 5 5 5 0 Calponin family repeat PP2C PF00481.21 KXZ44174.1 - 2.6e-46 158.3 0.0 3.7e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXZ44174.1 - 1e-05 25.5 0.0 2.8e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) MCM_bind PF09739.9 KXZ44175.1 - 4.3e-91 306.1 0.0 1e-54 186.1 0.0 4.6 3 2 0 3 3 3 3 Mini-chromosome maintenance replisome factor NnrU PF07298.11 KXZ44175.1 - 3.1e-49 167.3 12.0 6.3e-49 166.3 12.0 1.5 1 0 0 1 1 1 1 NnrU protein Peptidase_C97 PF05903.14 KXZ44176.1 - 4.2e-16 59.1 0.0 1.8e-15 57.0 0.0 1.9 1 1 0 1 1 1 1 PPPDE putative peptidase domain TFIIA PF03153.13 KXZ44176.1 - 0.25 11.3 14.9 0.032 14.2 7.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cohesin_load PF10345.9 KXZ44177.1 - 3.5e-07 29.1 0.5 0.0088 14.5 0.1 2.2 2 0 0 2 2 2 2 Cohesin loading factor Pkinase_Tyr PF07714.17 KXZ44178.1 - 3.7e-31 108.4 0.0 4.4e-28 98.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ44178.1 - 4.4e-28 98.4 0.0 3.5e-25 88.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ44178.1 - 0.29 10.5 0.0 0.53 9.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4705 PF15788.5 KXZ44180.1 - 1.6 9.0 10.4 1.2 9.4 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4705) ATG16 PF08614.11 KXZ44181.1 - 0.0014 18.9 12.9 0.11 12.7 4.7 2.5 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Filament PF00038.21 KXZ44181.1 - 0.068 12.8 8.7 0.041 13.5 4.1 2.0 2 0 0 2 2 2 0 Intermediate filament protein APG6_N PF17675.1 KXZ44181.1 - 2.3 8.7 20.1 9.8 6.7 0.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 KXZ44181.1 - 3.7 6.4 14.7 2.9 6.7 7.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 KXZ44181.1 - 5.7 6.4 15.4 1.2 8.6 1.4 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Ank_4 PF13637.6 KXZ44182.1 - 9.2e-08 32.5 1.4 2.3 8.9 0.0 5.7 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44182.1 - 7.9e-07 29.6 0.1 0.67 10.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) WD40 PF00400.32 KXZ44183.1 - 9.7e-67 219.3 34.9 2.1e-10 41.0 0.6 13.2 12 1 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44183.1 - 2.3e-32 111.2 3.9 2.5e-06 27.7 0.0 8.2 5 1 4 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXZ44183.1 - 9.7e-12 44.5 0.2 2.1 8.4 0.0 7.6 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KXZ44183.1 - 2e-09 37.6 0.0 0.00035 20.5 0.0 4.5 4 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 KXZ44183.1 - 2e-09 37.6 2.0 0.14 12.1 0.3 6.7 3 2 2 5 5 5 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KXZ44183.1 - 1.6e-06 27.3 5.7 0.14 11.1 0.6 5.2 5 1 0 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KXZ44183.1 - 1.1e-05 25.9 2.9 1.2e-05 25.8 0.5 2.4 2 0 0 2 2 2 1 AAA ATPase domain Proteasome_A_N PF10584.9 KXZ44183.1 - 0.0034 17.0 0.0 1.2e+02 2.5 0.0 6.2 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature HEPN_Swt1 PF18731.1 KXZ44183.1 - 0.0036 17.6 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 Swt1-like HEPN IKI3 PF04762.12 KXZ44183.1 - 0.0052 14.9 1.9 2.2 6.2 0.0 4.4 2 2 2 4 4 4 1 IKI3 family DPPIV_N PF00930.21 KXZ44183.1 - 0.071 11.8 0.5 84 1.8 0.0 4.4 5 0 0 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region NACHT PF05729.12 KXZ44183.1 - 0.16 11.8 0.0 0.81 9.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Nup160 PF11715.8 KXZ44183.1 - 0.29 9.7 1.4 32 3.0 0.0 4.1 5 1 0 5 5 5 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KXZ44183.1 - 1.1 8.1 4.9 4.6 6.0 0.1 3.6 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Cu-oxidase_2 PF07731.14 KXZ44185.1 - 1.8e-36 124.9 0.3 2.3e-30 105.1 0.1 3.9 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.22 KXZ44185.1 - 4.5e-30 104.9 0.0 1.8e-28 99.7 0.0 3.1 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXZ44185.1 - 1.5e-23 83.1 0.0 5.3e-23 81.3 0.0 2.0 1 0 0 1 1 1 1 Multicopper oxidase Metallophos PF00149.28 KXZ44186.1 - 8.6e-07 29.7 0.0 1.5e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ44186.1 - 0.00065 19.9 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 KXZ44186.1 - 0.15 10.3 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase DUF872 PF05915.12 KXZ44187.1 - 4e-18 65.6 0.1 4.3e-18 65.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) TM140 PF14985.6 KXZ44187.1 - 0.063 12.8 0.1 0.075 12.6 0.1 1.1 1 0 0 1 1 1 0 TM140 protein family Gram_pos_anchor PF00746.21 KXZ44187.1 - 7.9 6.5 6.3 0.62 10.1 1.6 1.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif zf-CCCH PF00642.24 KXZ44188.1 - 5.3e-06 26.2 2.0 0.00039 20.3 0.0 2.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXZ44188.1 - 0.072 13.2 0.2 0.072 13.2 0.2 2.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_2 PF14608.6 KXZ44188.1 - 7.4 7.2 8.8 23 5.6 0.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Spt5-NGN PF03439.13 KXZ44189.1 - 9.5e-21 73.5 0.0 2.2e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KXZ44189.1 - 5.9e-11 41.9 20.8 0.00061 19.7 0.7 6.0 5 0 0 5 5 5 4 KOW motif Spt5_N PF11942.8 KXZ44189.1 - 9.6e-09 36.1 12.4 9.6e-09 36.1 12.4 3.4 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal TPR_2 PF07719.17 KXZ44190.1 - 0.0004 20.3 0.2 0.056 13.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ44190.1 - 0.00055 19.6 0.5 0.04 13.7 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ44190.1 - 0.0047 17.4 0.0 0.016 15.7 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ44190.1 - 0.0048 17.4 0.8 1.2 9.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat PDZ PF00595.24 KXZ44190.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain TPR_21 PF09976.9 KXZ44190.1 - 0.025 14.3 0.3 0.61 9.8 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain SRP14 PF02290.15 KXZ44191.1 - 2.2e-09 37.5 0.0 3.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein zf-MYND PF01753.18 KXZ44192.1 - 3.5e-08 33.4 8.7 8.2e-08 32.2 8.7 1.7 1 0 0 1 1 1 1 MYND finger PsbQ PF05757.11 KXZ44193.1 - 0.024 14.4 2.2 0.034 13.9 2.2 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Abhydrolase_6 PF12697.7 KXZ44193.1 - 0.052 14.1 3.3 0.06 13.9 3.3 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Porin_5 PF16930.5 KXZ44193.1 - 0.087 11.3 0.2 0.08 11.4 0.2 1.1 1 0 0 1 1 1 0 Putative porin DUF5350 PF17299.2 KXZ44193.1 - 0.16 12.5 1.6 4.3 7.9 0.6 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5350) Gp45_2 PF17470.2 KXZ44193.1 - 0.25 11.3 0.0 0.39 10.7 0.0 1.2 1 0 0 1 1 1 0 Phage gene product 45.2 WD40 PF00400.32 KXZ44194.1 - 1.8e-35 120.4 14.2 0.00034 21.4 0.3 12.4 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44194.1 - 2.9e-05 24.3 0.4 4.1 7.8 0.0 5.3 4 2 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXZ44194.1 - 0.00011 21.0 0.1 0.0038 15.9 0.0 2.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 WD40 PF00400.32 KXZ44195.1 - 2.4e-25 88.3 15.9 3.6e-05 24.5 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44195.1 - 5.9e-11 42.5 0.1 0.014 15.7 0.0 5.2 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KXZ44195.1 - 0.015 14.1 0.0 3.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like BBS2_Mid PF14783.6 KXZ44195.1 - 0.045 13.8 0.0 6 7.0 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region UAA PF08449.11 KXZ44196.1 - 2.5e-52 178.0 5.2 3.4e-52 177.5 5.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXZ44196.1 - 3.3e-10 40.3 11.0 5.8e-07 29.8 2.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family Arm PF00514.23 KXZ44196.1 - 0.00047 20.1 6.7 0.38 10.9 0.0 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Vac14_Fig4_bd PF11916.8 KXZ44196.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding V-ATPase_H_C PF11698.8 KXZ44196.1 - 0.28 11.3 3.5 0.7 10.0 0.0 2.9 3 1 1 4 4 4 0 V-ATPase subunit H HEAT_EZ PF13513.6 KXZ44196.1 - 0.8 10.3 7.8 27 5.4 4.6 3.3 3 0 0 3 3 3 0 HEAT-like repeat Shisa PF13908.6 KXZ44198.1 - 0.029 14.6 2.3 0.095 12.9 2.3 1.9 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ABC1 PF03109.16 KXZ44199.1 - 1e-27 96.6 0.0 3.1e-27 95.1 0.0 1.8 2 0 0 2 2 2 1 ABC1 family VMA21 PF09446.10 KXZ44200.1 - 5.4e-11 42.4 3.2 6.2e-11 42.2 3.2 1.1 1 0 0 1 1 1 1 VMA21-like domain zf-MYND PF01753.18 KXZ44201.1 - 3.9e-07 30.1 8.2 7.1e-07 29.2 8.2 1.4 1 0 0 1 1 1 1 MYND finger RhlB PF12300.8 KXZ44202.1 - 0.61 10.2 11.5 0.1 12.7 5.4 2.6 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB DUF1736 PF08409.11 KXZ44203.1 - 6.4e-20 70.9 0.0 1.3e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 KXZ44203.1 - 0.04 14.1 12.4 0.43 10.8 0.1 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat PIN_6 PF17146.4 KXZ44204.1 - 2.5e-27 95.2 0.1 2.5e-27 95.2 0.1 2.3 3 0 0 3 3 3 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KXZ44204.1 - 4.2e-21 74.9 0.1 7.1e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like TFIIA PF03153.13 KXZ44204.1 - 0.033 14.2 9.3 0.043 13.8 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RRN7 PF11781.8 KXZ44204.1 - 0.23 11.2 1.2 0.45 10.3 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 MORN PF02493.20 KXZ44206.1 - 1.7e-28 96.7 38.6 4.8e-05 23.0 0.3 8.5 9 0 0 9 9 9 7 MORN repeat Filamin PF00630.19 KXZ44206.1 - 3.5e-24 85.6 0.0 8.4e-14 52.2 0.0 2.7 3 0 0 3 3 3 2 Filamin/ABP280 repeat TAL_FSA PF00923.19 KXZ44207.1 - 3.1e-89 299.1 0.0 3.6e-89 298.9 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PAN_4 PF14295.6 KXZ44208.1 - 6e-07 29.3 11.3 6e-07 29.3 11.3 2.1 2 1 0 2 2 2 1 PAN domain LigT_PEase PF02834.16 KXZ44208.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 LigT like Phosphoesterase K_channel_TID PF07941.11 KXZ44210.1 - 0.013 15.9 7.9 0.013 15.9 7.9 14.8 12 4 3 15 15 15 0 Potassium channel Kv1.4 tandem inactivation domain Bacillus_PapR PF05968.11 KXZ44210.1 - 0.069 13.0 4.2 0.1 12.5 0.7 2.9 2 0 0 2 2 2 0 Bacillus PapR protein RAP PF08373.10 KXZ44211.1 - 0.035 14.2 0.0 0.035 14.2 0.0 2.0 2 0 0 2 2 2 0 RAP domain Dimerisation2 PF16864.5 KXZ44211.1 - 0.18 11.8 7.9 1.1 9.3 0.1 4.0 4 0 0 4 4 4 0 Dimerisation domain SelP_N PF04592.14 KXZ44211.1 - 3.3 7.1 6.1 5.3 6.4 6.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SMC_hinge PF06470.13 KXZ44212.1 - 0.14 12.5 0.3 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain DUF1451 PF07295.11 KXZ44213.1 - 2.2 8.3 6.3 1.9 8.5 4.6 1.7 1 1 0 1 1 1 0 Zinc-ribbon containing domain THOC7 PF05615.13 KXZ44213.1 - 6.3 7.1 14.8 16 5.7 14.8 1.7 1 0 0 1 1 1 0 Tho complex subunit 7 Nkap_C PF06047.11 KXZ44214.1 - 3.3e-44 149.1 4.0 6.9e-44 148.1 4.0 1.5 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain RRM_1 PF00076.22 KXZ44215.1 - 6.9e-41 137.9 0.0 8e-21 73.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXZ44215.1 - 4.8e-06 26.5 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 KXZ44215.1 - 0.00095 19.2 0.2 0.37 10.9 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 YflT PF11181.8 KXZ44215.1 - 0.037 14.5 0.0 3.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF4684 PF15736.5 KXZ44215.1 - 0.047 12.4 6.7 0.037 12.7 5.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4684) Nup35_RRM_2 PF14605.6 KXZ44215.1 - 0.049 13.6 0.0 7.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif EI24 PF07264.11 KXZ44216.1 - 1.7e-29 103.4 10.7 2.6e-29 102.7 10.7 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF1616 PF07760.11 KXZ44216.1 - 0.71 9.2 2.3 1 8.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Asp_Arg_Hydrox PF05118.15 KXZ44217.1 - 5.4e-09 36.1 0.1 1.6e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase PQQ_2 PF13360.6 KXZ44217.1 - 6e-08 32.5 4.5 8.4e-07 28.8 1.6 2.6 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 KXZ44217.1 - 0.0012 18.7 0.0 0.2 11.7 0.0 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat Phage_GPD PF05954.11 KXZ44217.1 - 0.079 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Glucokinase PF02685.16 KXZ44218.1 - 6.5e-85 284.9 0.0 7.4e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Glucokinase TMF_DNA_bd PF12329.8 KXZ44219.1 - 0.0012 18.8 0.1 0.077 13.0 0.0 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KXZ44219.1 - 0.027 15.1 0.3 5.3 7.7 0.0 2.5 2 0 0 2 2 2 0 SlyX DUF742 PF05331.11 KXZ44219.1 - 0.064 13.1 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF742) SelP_N PF04592.14 KXZ44220.1 - 0.008 15.6 16.8 0.013 14.9 16.8 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region TPR_1 PF00515.28 KXZ44221.1 - 1.1e-24 85.2 4.4 1e-05 25.1 0.1 8.0 7 1 1 8 8 8 4 Tetratricopeptide repeat DnaJ PF00226.31 KXZ44221.1 - 4.6e-24 84.3 2.8 4.6e-24 84.3 2.8 2.8 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KXZ44221.1 - 5e-19 66.8 24.3 1.7e-05 24.6 0.1 9.3 8 1 2 10 10 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ44221.1 - 1.4e-15 56.1 2.7 0.0013 18.8 0.0 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ44221.1 - 4.7e-14 52.6 24.0 6.6e-06 26.5 0.4 6.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ44221.1 - 1.5e-06 27.8 8.6 0.016 14.9 0.0 5.6 6 1 1 7 7 7 2 TPR repeat TPR_16 PF13432.6 KXZ44221.1 - 2.5e-06 28.0 46.1 0.045 14.4 0.4 7.3 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ44221.1 - 1.1e-05 25.6 32.7 0.0013 18.9 1.5 7.3 5 3 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ44221.1 - 7.9e-05 22.8 4.9 0.14 12.4 0.2 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXZ44221.1 - 0.00049 20.7 42.0 0.091 13.6 0.1 9.9 4 2 6 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ44221.1 - 0.0026 17.7 30.0 1.1 9.4 0.1 9.1 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ44221.1 - 0.0043 17.2 1.7 0.14 12.3 0.1 5.1 5 1 1 6 6 5 2 Tetratricopeptide repeat Thioredoxin_15 PF18403.1 KXZ44221.1 - 0.045 13.7 0.6 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain TPR_6 PF13174.6 KXZ44221.1 - 0.16 12.6 0.0 0.16 12.6 0.0 7.9 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ44221.1 - 0.41 11.4 0.2 0.41 11.4 0.2 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXZ44221.1 - 0.91 10.0 0.0 0.91 10.0 0.0 3.5 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation SHNi-TPR PF10516.9 KXZ44221.1 - 1.7 8.2 5.8 18 4.9 0.1 3.9 4 0 0 4 4 4 0 SHNi-TPR Cys_rich_FGFR PF00839.17 KXZ44222.1 - 7.8e-95 311.0 34.3 1e-11 44.8 0.7 11.2 11 0 0 11 11 11 11 Cysteine rich repeat CP12 PF02672.15 KXZ44222.1 - 0.041 14.6 0.1 0.19 12.5 0.1 2.2 1 0 0 1 1 1 0 CP12 domain GAS PF13851.6 KXZ44224.1 - 0.00039 19.8 1.5 0.00039 19.8 1.5 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KXZ44224.1 - 0.004 17.2 5.3 0.004 17.2 5.3 3.0 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 KXZ44224.1 - 0.021 14.8 2.4 0.021 14.8 2.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 KXZ44224.1 - 0.026 15.0 18.9 0.039 14.4 4.3 2.2 1 1 1 2 2 2 0 Fez1 Serglycin PF04360.12 KXZ44224.1 - 0.19 11.6 1.1 0.34 10.9 1.1 1.5 1 0 0 1 1 1 0 Serglycin Sec20 PF03908.13 KXZ44224.1 - 0.27 11.2 1.8 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 Sec20 zf-PARP PF00645.18 KXZ44225.1 - 1.1e-07 32.6 0.0 1.8e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Thioredoxin PF00085.20 KXZ44226.1 - 3.2e-26 91.3 0.0 6.7e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.12 KXZ44226.1 - 4e-21 75.7 2.9 7.5e-21 74.8 2.9 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 KXZ44226.1 - 4e-08 33.0 0.0 5.3e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXZ44226.1 - 4.2e-06 27.2 0.1 1e-05 25.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ44226.1 - 0.0022 18.3 0.0 0.0052 17.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KXZ44226.1 - 0.026 14.2 0.2 0.071 12.8 0.0 1.7 1 1 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 KXZ44226.1 - 0.034 14.1 0.0 0.081 12.8 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 KXZ44226.1 - 0.069 13.1 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE ERp29_N PF07912.13 KXZ44226.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 KXZ44226.1 - 0.11 12.6 0.2 0.47 10.7 0.1 2.2 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KXZ44226.1 - 0.15 11.8 0.1 0.43 10.4 0.0 1.8 3 0 0 3 3 3 0 Thioredoxin DEAD PF00270.29 KXZ44227.1 - 8.6e-34 116.8 0.0 1.3e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ferritin_2 PF13668.6 KXZ44227.1 - 5.8e-29 101.0 0.1 9.8e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain Helicase_C PF00271.31 KXZ44227.1 - 2.8e-08 34.1 0.0 3.7e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ44227.1 - 0.00023 21.2 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_16 PF00722.21 KXZ44228.1 - 8.4e-22 77.5 0.7 6.9e-21 74.5 0.7 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXZ44228.1 - 2.3e-10 39.5 0.4 5.5e-05 21.8 0.0 2.1 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Fiji_64_capsid PF05880.11 KXZ44228.1 - 0.11 11.0 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein GTP_EFTU PF00009.27 KXZ44229.1 - 1.3e-57 194.4 0.2 2e-57 193.9 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXZ44229.1 - 1.2e-26 93.3 0.0 2.9e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXZ44229.1 - 5.1e-17 62.0 5.0 5.1e-17 62.0 5.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ44229.1 - 3.1e-05 24.0 0.2 0.00011 22.2 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXZ44229.1 - 0.0098 15.8 0.1 0.043 13.7 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 KXZ44229.1 - 0.017 14.7 0.2 0.08 12.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KXZ44229.1 - 0.051 13.3 0.2 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Hydrolase_4 PF12146.8 KXZ44230.1 - 6.4e-10 38.7 0.0 8.9e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ44230.1 - 2.4e-07 31.6 0.3 3.1e-07 31.2 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ44230.1 - 1.1e-06 28.6 0.0 0.00011 22.0 0.0 2.8 1 1 2 3 3 3 1 alpha/beta hydrolase fold Ndr PF03096.14 KXZ44230.1 - 0.14 10.8 0.0 0.9 8.2 0.0 2.0 1 1 0 1 1 1 0 Ndr family Methyltransf_32 PF13679.6 KXZ44231.1 - 3.5e-16 59.6 1.1 2.7e-15 56.7 1.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ44231.1 - 6.7e-13 48.7 0.0 9.5e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ44231.1 - 4.6e-11 43.3 0.1 8.1e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXZ44231.1 - 2.7e-07 30.2 0.0 3.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 KXZ44231.1 - 7.1e-07 29.9 0.0 1.2e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44231.1 - 1.8e-06 28.5 0.1 3.7e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ44231.1 - 1.8e-06 27.6 0.0 2.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXZ44231.1 - 8.5e-06 25.7 0.0 1.4e-05 25.0 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain GidB PF02527.15 KXZ44231.1 - 0.00024 20.5 0.0 0.00034 20.0 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.13 KXZ44231.1 - 0.00043 19.8 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KXZ44231.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 KXZ44231.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KXZ44231.1 - 0.035 13.8 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein TRM13 PF05206.14 KXZ44231.1 - 0.04 13.4 0.6 16 4.9 0.4 2.9 3 0 0 3 3 3 0 Methyltransferase TRM13 Ubie_methyltran PF01209.18 KXZ44231.1 - 0.042 13.2 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Histone PF00125.24 KXZ44232.1 - 4.1e-41 140.4 1.5 4.1e-41 140.4 1.5 1.9 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXZ44232.1 - 9.2e-06 25.7 2.0 1.5e-05 25.0 0.1 2.1 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ44232.1 - 0.0012 19.2 0.5 0.0022 18.3 0.0 1.7 2 0 0 2 2 2 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXZ44232.1 - 0.013 15.7 0.2 0.053 13.8 0.2 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ44232.1 - 0.032 14.3 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ44232.1 - 0.077 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Myb_DNA-binding PF00249.31 KXZ44233.1 - 1.2e-21 76.6 1.3 6.6e-14 51.8 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ44233.1 - 1e-18 67.3 0.9 9.4e-10 38.6 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXZ44233.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KXZ44233.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Brix PF04427.18 KXZ44234.1 - 6.8e-34 117.7 0.0 9.2e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain ADP_ribosyl_GH PF03747.14 KXZ44235.1 - 2e-31 109.8 6.9 3.2e-30 105.9 6.9 2.2 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase APC_N_CC PF16689.5 KXZ44235.1 - 0.022 14.8 1.6 0.12 12.5 1.0 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Motile_Sperm PF00635.26 KXZ44236.1 - 2.8e-26 91.5 3.1 3.9e-26 91.0 3.1 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KXZ44236.1 - 0.064 13.5 0.4 0.11 12.8 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 131-like UTP15_C PF09384.10 KXZ44237.1 - 1.2e-41 141.8 0.0 1.7e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KXZ44237.1 - 1.4e-21 76.4 10.5 0.00029 21.6 0.6 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44237.1 - 4.4e-08 33.3 0.0 0.0071 16.6 0.0 3.7 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pmp3 PF01679.17 KXZ44238.1 - 4.6e-21 74.8 1.9 5e-21 74.6 1.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Rad10 PF03834.14 KXZ44239.1 - 1.9e-20 73.0 0.0 3.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KXZ44239.1 - 0.14 12.8 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain MRPL52 PF18699.1 KXZ44239.1 - 0.22 11.7 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Rad17 PF03215.15 KXZ44240.1 - 1.9e-11 44.2 0.0 0.00029 20.8 0.0 3.2 2 1 1 3 3 3 3 Rad17 P-loop domain AAA_22 PF13401.6 KXZ44240.1 - 0.0013 19.0 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KXZ44240.1 - 0.0019 18.5 0.4 0.006 16.9 0.4 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KXZ44240.1 - 0.011 16.2 2.8 0.051 14.0 2.8 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KXZ44240.1 - 0.021 15.2 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXZ44240.1 - 0.1 12.9 0.0 1 9.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ44240.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KXZ44240.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.22 KXZ44240.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABM PF03992.16 KXZ44241.1 - 2.7e-11 43.4 0.0 1.4e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Plus-3 PF03126.18 KXZ44243.1 - 3e-21 76.0 0.0 5.5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Plus-3 domain GEMIN8 PF15348.6 KXZ44243.1 - 6.6 7.0 17.7 18 5.5 0.1 2.4 2 1 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Chorion_3 PF05387.11 KXZ44244.1 - 1.6 8.3 3.9 0.62 9.7 1.6 1.4 2 0 0 2 2 2 0 Chorion family 3 DUF4788 PF16032.5 KXZ44245.1 - 0.32 9.9 1.0 0.52 9.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) UPF0225 PF17775.1 KXZ44246.1 - 1.7e-08 35.1 0.0 2.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain SBP PF03110.14 KXZ44247.1 - 6.4e-30 103.3 8.1 1.3e-29 102.3 8.1 1.5 1 0 0 1 1 1 1 SBP domain Ank_3 PF13606.6 KXZ44247.1 - 0.013 15.9 0.3 1.6 9.6 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 KXZ44247.1 - 0.044 14.4 0.1 0.096 13.3 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) AF-4 PF05110.13 KXZ44248.1 - 0.025 12.7 5.1 0.033 12.3 5.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SelR PF01641.18 KXZ44249.1 - 3.9e-39 133.5 0.0 5.3e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 SelR domain WD40 PF00400.32 KXZ44251.1 - 9.9e-17 61.0 0.0 2.1e-07 31.5 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44251.1 - 2.8e-11 43.6 0.1 2.9e-06 27.5 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RabGAP-TBC PF00566.18 KXZ44252.1 - 1.1e-30 107.0 2.7 1.2e-30 106.8 2.7 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain APG5 PF04106.12 KXZ44252.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 Trehalase PF01204.18 KXZ44253.1 - 1.3e-103 347.6 0.0 4e-103 346.0 0.0 1.7 1 1 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 KXZ44253.1 - 0.0061 15.4 0.5 0.021 13.6 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Peptidase_M10_C PF08548.11 KXZ44253.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal Patatin PF01734.22 KXZ44254.1 - 2.2e-07 31.3 0.5 8.3e-06 26.1 0.5 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase FliJ PF02050.16 KXZ44254.1 - 0.11 12.8 5.4 0.23 11.7 5.4 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein Apt1 PF10351.9 KXZ44254.1 - 0.7 8.7 3.2 0.98 8.2 3.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SIKE PF05769.11 KXZ44254.1 - 1 9.2 6.2 0.17 11.8 2.4 1.6 2 0 0 2 2 2 0 SIKE family BLOC1_2 PF10046.9 KXZ44254.1 - 1.3 9.3 5.1 2.2 8.6 2.5 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PsaN PF05479.11 KXZ44255.1 - 0.049 13.8 3.3 0.053 13.7 3.3 1.1 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) PepSY_2 PF13670.6 KXZ44255.1 - 3.2 7.8 5.9 0.18 11.9 0.5 1.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF4164 PF13747.6 KXZ44256.1 - 0.014 15.7 2.2 0.025 14.8 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ZapB PF06005.12 KXZ44256.1 - 0.13 12.7 3.0 0.46 11.0 0.4 2.4 1 1 1 2 2 2 0 Cell division protein ZapB PCMT PF01135.19 KXZ44257.1 - 1.6e-35 122.8 0.1 9.2e-35 120.3 0.1 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXZ44257.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44257.1 - 0.00078 20.0 0.0 0.0014 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXZ44257.1 - 0.0014 18.6 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ44257.1 - 0.0057 17.3 0.0 0.0086 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KXZ44257.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KXZ44257.1 - 0.028 14.2 0.0 0.033 14.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXZ44257.1 - 0.04 13.5 0.1 0.077 12.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KXZ44257.1 - 0.046 13.1 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KXZ44257.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FA_desaturase PF00487.24 KXZ44259.1 - 0.031 14.1 1.4 0.09 12.6 1.4 1.7 1 0 0 1 1 1 0 Fatty acid desaturase Collagen_mid PF15984.5 KXZ44259.1 - 0.065 13.0 0.1 0.065 13.0 0.1 4.1 4 0 0 4 4 4 0 Bacterial collagen, middle region Hpt PF01627.23 KXZ44259.1 - 3.4 8.0 9.5 0.32 11.3 2.7 2.8 3 0 0 3 3 3 0 Hpt domain Myb_Cef PF11831.8 KXZ44260.1 - 2.3e-41 142.0 0.2 2.3e-41 142.0 0.2 3.6 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.6 KXZ44260.1 - 1.8e-17 63.3 2.9 6.8e-09 35.9 0.0 3.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXZ44260.1 - 2e-15 56.7 5.3 9.7e-08 32.1 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Sel1 PF08238.12 KXZ44261.1 - 6.1e-45 150.6 47.8 2.2e-08 34.5 0.6 12.0 13 0 0 13 13 13 9 Sel1 repeat Pro_CA PF00484.19 KXZ44262.1 - 2.6e-42 144.8 0.6 3.5e-42 144.3 0.6 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 KXZ44263.1 - 1.5e-49 168.3 0.4 2.4e-49 167.6 0.4 1.3 1 0 0 1 1 1 1 Carbonic anhydrase CopD PF05425.13 KXZ44264.1 - 0.071 13.5 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 Copper resistance protein D MEKHLA PF08670.11 KXZ44265.1 - 5e-35 120.5 0.0 7.7e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 MEKHLA domain PAS_9 PF13426.7 KXZ44265.1 - 0.079 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 PAS domain WHEP-TRS PF00458.20 KXZ44265.1 - 0.26 11.5 4.4 0.52 10.5 4.4 1.5 1 0 0 1 1 1 0 WHEP-TRS domain zf-C2HC_2 PF13913.6 KXZ44266.1 - 7.6e-57 188.3 38.5 3.6e-08 33.1 0.5 9.3 9 0 0 9 9 9 9 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KXZ44266.1 - 4.4e-11 42.6 21.1 1.5 9.4 0.0 9.4 9 0 0 9 9 9 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXZ44266.1 - 4.2e-07 30.2 40.2 1.1 10.3 0.2 9.6 9 0 0 9 9 9 2 C2H2-type zinc finger zf-CpG_bind_C PF12269.8 KXZ44266.1 - 5.4e-06 26.4 7.6 4.2 7.1 0.0 6.4 8 0 0 8 8 8 1 CpG binding protein zinc finger C terminal domain zf-H2C2_2 PF13465.6 KXZ44266.1 - 4e-05 23.8 14.2 38 5.0 0.0 9.1 9 0 0 9 9 8 0 Zinc-finger double domain TRAF6_Z2 PF18048.1 KXZ44266.1 - 0.0025 17.8 15.6 8.5 6.6 0.1 6.3 6 0 0 6 6 6 1 TNF receptor-associated factor 6 zinc finger 2 Zn-C2H2_12 PF18112.1 KXZ44266.1 - 0.0035 17.8 14.9 0.26 11.8 0.1 5.2 6 0 0 6 6 6 2 Autophagy receptor zinc finger-C2H2 domain Jas PF16135.5 KXZ44266.1 - 0.0052 16.9 0.1 34 4.7 0.0 3.7 3 0 0 3 3 3 0 TPL-binding domain in jasmonate signalling SH3_4 PF06347.13 KXZ44266.1 - 0.014 15.2 0.0 6 6.8 0.0 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain RA PF00788.23 KXZ44266.1 - 0.031 14.9 0.0 16 6.2 0.0 2.3 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain DUF2318 PF10080.9 KXZ44266.1 - 0.032 14.3 19.2 0.7 10.0 0.1 7.4 9 0 0 9 9 9 0 Predicted membrane protein (DUF2318) UBZ_FAAP20 PF15750.5 KXZ44266.1 - 0.035 14.0 4.5 2.8 8.0 0.1 3.9 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger DUF1815 PF08844.10 KXZ44266.1 - 0.083 12.9 0.3 38 4.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1815) CxC7 PF18866.1 KXZ44266.1 - 0.083 13.0 4.4 15 5.8 0.0 5.2 5 0 0 5 5 5 0 CxC7 like cysteine cluster associated with KDZ transposases zf-ACC PF17848.1 KXZ44266.1 - 0.35 11.0 0.1 0.35 11.0 0.1 5.5 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain zf-RING_7 PF02591.15 KXZ44266.1 - 0.78 10.0 18.7 2.1 8.6 0.1 5.7 6 0 0 6 6 6 0 C4-type zinc ribbon domain zf-Di19 PF05605.12 KXZ44266.1 - 2.2 8.7 26.9 15 5.9 0.2 7.4 8 0 0 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding GcpE PF04551.14 KXZ44266.1 - 2.4 7.1 13.3 19 4.2 0.1 4.3 5 0 0 5 5 5 0 GcpE protein zinc_ribbon_2 PF13240.6 KXZ44266.1 - 2.9 7.8 13.5 5.5 6.8 0.1 4.6 4 0 0 4 4 4 0 zinc-ribbon domain zf_UBZ PF18439.1 KXZ44266.1 - 8.3 6.1 20.3 12 5.6 0.0 7.2 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger PfkB PF00294.24 KXZ44268.1 - 5.3e-34 117.9 2.9 4.9e-26 91.7 0.1 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF2267 PF10025.9 KXZ44268.1 - 0.14 12.4 0.1 2.1 8.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) EamA PF00892.20 KXZ44269.1 - 5e-07 30.0 19.8 5.8e-07 29.8 19.8 1.1 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 KXZ44269.1 - 0.0034 16.8 5.5 0.0042 16.5 5.5 1.2 1 1 0 1 1 1 1 Triose-phosphate Transporter family TMEM234 PF10639.9 KXZ44269.1 - 0.11 12.5 8.6 0.28 11.3 8.6 1.7 1 1 0 1 1 1 0 Putative transmembrane family 234 WD40 PF00400.32 KXZ44270.1 - 6.9e-18 64.7 1.0 4.1e-05 24.3 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44270.1 - 2.9e-10 40.3 0.0 0.012 15.9 0.0 4.2 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain IRF PF00605.17 KXZ44270.1 - 0.00053 20.2 0.2 0.0014 18.9 0.1 1.7 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor Nup160 PF11715.8 KXZ44270.1 - 0.0033 16.2 0.1 0.61 8.7 0.1 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KXZ44270.1 - 0.02 14.5 0.2 1.9 8.0 0.0 2.2 1 1 0 2 2 2 0 PQQ-like domain zf-C4H2 PF10146.9 KXZ44271.1 - 0.0011 19.3 1.1 0.0011 19.3 1.1 3.2 3 1 0 3 3 3 1 Zinc finger-containing protein AAA_13 PF13166.6 KXZ44271.1 - 0.0026 16.5 14.1 0.0026 16.5 14.1 2.1 2 0 0 2 2 2 1 AAA domain Occludin_ELL PF07303.13 KXZ44271.1 - 0.16 12.7 0.2 0.16 12.7 0.2 3.8 2 2 2 4 4 4 0 Occludin homology domain DUF4407 PF14362.6 KXZ44271.1 - 1.1 8.5 49.9 0.44 9.9 6.3 3.7 2 1 1 4 4 4 0 Domain of unknown function (DUF4407) GREB1 PF15782.5 KXZ44271.1 - 5 4.1 7.5 7.4 3.5 7.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SQS_PSY PF00494.19 KXZ44272.1 - 1.1e-44 152.9 8.3 2.2e-32 112.6 2.2 2.0 2 0 0 2 2 2 2 Squalene/phytoene synthase Peptidase_C12 PF01088.21 KXZ44273.1 - 8.4e-39 133.5 0.0 9.3e-24 84.3 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 AA_permease_2 PF13520.6 KXZ44274.1 - 1.5e-55 188.8 45.0 1.5e-55 188.8 45.0 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXZ44274.1 - 3.5e-34 118.2 37.5 5.5e-34 117.6 37.5 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KXZ44274.1 - 2.5e-15 56.3 0.9 2.5e-15 56.3 0.9 4.2 5 0 0 5 5 5 1 C-terminus of AA_permease DUF2618 PF10940.8 KXZ44274.1 - 0.81 9.5 2.5 32 4.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) DUF962 PF06127.11 KXZ44274.1 - 6.2 7.0 6.7 1.1e+02 3.0 0.0 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF962) Band_7 PF01145.25 KXZ44275.1 - 2.5e-21 76.5 0.2 4.1e-21 75.8 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KXZ44275.1 - 0.092 12.4 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF959 PF06121.14 KXZ44275.1 - 0.1 12.9 0.6 0.16 12.2 0.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) DNA_pol_D_N PF18018.1 KXZ44275.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Transket_pyr PF02779.24 KXZ44276.1 - 2.1e-45 154.6 0.0 4.2e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXZ44276.1 - 2.5e-34 117.8 0.2 4.5e-34 117.0 0.2 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KXZ44276.1 - 0.00057 20.2 0.2 0.0033 17.7 0.1 2.2 1 1 1 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Fcf2 PF08698.11 KXZ44277.1 - 1.4e-30 105.5 0.1 1.4e-30 105.5 0.1 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Pkinase_Tyr PF07714.17 KXZ44278.1 - 9.8e-69 231.5 0.0 1.4e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ44278.1 - 5.4e-56 189.9 0.0 7.7e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EDR1 PF14381.6 KXZ44278.1 - 4.2e-48 163.7 0.0 5.7e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 APH PF01636.23 KXZ44278.1 - 0.0011 18.9 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ44278.1 - 0.011 14.7 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain MatE PF01554.18 KXZ44278.1 - 1.1 8.8 3.6 2.4 7.8 3.6 1.5 1 0 0 1 1 1 0 MatE Slu7 PF11708.8 KXZ44279.1 - 8.4e-85 284.8 7.0 8.4e-85 284.8 7.0 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KXZ44279.1 - 0.045 13.5 0.4 0.11 12.2 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle FeThRed_B PF02943.15 KXZ44280.1 - 2.8e-43 146.2 2.9 3.3e-43 146.0 2.9 1.0 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain FAD-oxidase_C PF02913.19 KXZ44280.1 - 0.089 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain HMG_box PF00505.19 KXZ44281.1 - 9.6e-13 48.4 2.1 2.4e-12 47.1 2.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXZ44281.1 - 1.6e-10 41.4 1.8 2.6e-10 40.7 1.8 1.3 1 0 0 1 1 1 1 HMG-box domain CBFD_NFYB_HMF PF00808.23 KXZ44281.1 - 8.5e-07 29.2 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ44281.1 - 1.4e-05 25.4 0.1 0.00013 22.3 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXZ44281.1 - 0.0095 16.1 0.0 0.022 14.9 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KXZ44281.1 - 0.052 13.6 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Polysacc_synt_4 PF04669.13 KXZ44281.1 - 0.065 12.8 0.2 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis Trigger_C PF05698.14 KXZ44281.1 - 0.079 13.0 0.7 0.15 12.1 0.7 1.4 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus CoA_binding PF02629.19 KXZ44282.1 - 3.6e-30 104.5 0.3 3.6e-30 104.5 0.3 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KXZ44282.1 - 1.8e-22 79.8 0.3 3.1e-22 79.0 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXZ44282.1 - 1.9e-11 43.9 0.1 4e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KXZ44282.1 - 0.003 18.0 0.1 0.009 16.5 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Phage_holin_8 PF16931.5 KXZ44282.1 - 0.046 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Putative phage holin tRNA-synt_2 PF00152.20 KXZ44283.1 - 4.8e-80 269.0 0.1 8.1e-66 222.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXZ44283.1 - 5.8e-07 29.4 0.0 2.3e-06 27.5 0.0 2.1 2 0 0 2 2 1 1 OB-fold nucleic acid binding domain WHEP-TRS PF00458.20 KXZ44283.1 - 4.1e-05 23.6 9.6 0.00013 22.1 9.6 1.9 1 0 0 1 1 1 1 WHEP-TRS domain Spc7 PF08317.11 KXZ44283.1 - 0.019 13.8 2.2 0.14 11.0 0.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein tRNA-synt_2d PF01409.20 KXZ44283.1 - 0.038 13.5 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) End3 PF12761.7 KXZ44283.1 - 0.039 14.1 0.8 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 OmpH PF03938.14 KXZ44283.1 - 0.062 13.6 4.5 5.1 7.4 3.3 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Desulfoferrodox PF01880.18 KXZ44283.1 - 0.073 13.7 0.0 0.28 11.8 0.0 2.0 1 0 0 1 1 1 0 Desulfoferrodoxin Csm1_N PF18504.1 KXZ44283.1 - 1.1 9.7 5.2 2.8 8.3 0.2 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 KXZ44283.1 - 1.1 9.0 7.5 3.4 7.5 0.3 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF3138 PF11336.8 KXZ44283.1 - 1.2 7.7 6.4 3.8 6.0 6.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Seryl_tRNA_N PF02403.22 KXZ44283.1 - 2.7 8.2 9.1 4.8 7.5 0.2 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Bap31_Bap29_C PF18035.1 KXZ44283.1 - 5.3 7.1 7.1 30 4.7 1.6 3.4 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain CLP1_P PF16575.5 KXZ44284.1 - 5.4e-67 225.2 0.0 9.4e-67 224.5 0.0 1.4 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KXZ44284.1 - 2.3e-25 89.3 0.0 4.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 KXZ44284.1 - 8e-22 77.3 0.0 1.5e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 KXZ44284.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KXZ44284.1 - 0.017 15.4 0.0 0.042 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ44284.1 - 0.053 13.9 0.1 0.18 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXZ44284.1 - 0.081 13.5 0.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXZ44284.1 - 0.089 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KXZ44284.1 - 0.092 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KXZ44284.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ldh_1_N PF00056.23 KXZ44285.1 - 6.4e-47 159.2 1.1 1.1e-46 158.5 0.2 1.8 3 0 0 3 3 3 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXZ44285.1 - 5.9e-46 156.5 0.0 9e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sacchrp_dh_NADP PF03435.18 KXZ44285.1 - 0.031 14.5 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXZ44285.1 - 0.14 12.6 0.2 0.7 10.4 0.0 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KXZ44286.1 - 3.3e-10 40.0 0.1 9.6e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ44286.1 - 5.9e-05 22.5 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ44286.1 - 0.017 15.8 9.1 0.039 14.6 9.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family GCV_T PF01571.21 KXZ44287.1 - 1.3e-88 296.7 0.0 1.6e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KXZ44287.1 - 8.3e-22 76.9 0.1 2.1e-21 75.6 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 KXZ44287.1 - 0.0017 18.6 0.0 0.0056 16.8 0.0 1.9 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Sigma70_r4 PF04545.16 KXZ44288.1 - 5.6e-18 64.2 2.2 4.2e-17 61.4 0.9 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 KXZ44288.1 - 1e-17 64.0 9.1 1.6e-11 44.1 0.9 4.0 4 0 0 4 4 4 2 Sigma-70 region 3 Sigma70_r2 PF04542.14 KXZ44288.1 - 1.3e-15 56.9 0.0 3.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 T6PP_N PF18572.1 KXZ44288.1 - 0.076 12.9 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain HTH_3 PF01381.22 KXZ44288.1 - 0.077 13.1 0.1 2.5 8.2 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix Sigma70_r4_2 PF08281.12 KXZ44288.1 - 0.099 12.3 1.1 3.6 7.3 0.3 2.9 2 1 0 2 2 2 0 Sigma-70, region 4 HHH PF00633.23 KXZ44288.1 - 0.22 11.5 1.2 0.56 10.2 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif IQ PF00612.27 KXZ44289.1 - 2.3e-06 26.9 2.3 6e-06 25.6 2.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif HU-CCDC81_bac_2 PF18175.1 KXZ44289.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Ribosomal_L5_C PF00673.21 KXZ44290.1 - 0.0051 17.0 0.0 0.64 10.2 0.0 2.1 2 0 0 2 2 2 2 ribosomal L5P family C-terminus DUF3275 PF11679.8 KXZ44291.1 - 0.15 12.0 2.2 0.26 11.2 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Lipase_3 PF01764.25 KXZ44292.1 - 7.9e-20 71.2 0.0 2.1e-18 66.6 0.0 2.5 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_1 PF00561.20 KXZ44292.1 - 0.035 13.8 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Toprim_3 PF13362.6 KXZ44292.1 - 1.2 9.5 5.7 12 6.4 2.4 3.7 2 1 1 3 3 3 0 Toprim domain Sigma70_r2 PF04542.14 KXZ44293.1 - 6.4e-12 45.1 0.6 1.8e-11 43.6 0.2 2.1 2 1 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 KXZ44293.1 - 6.2e-08 32.6 0.3 0.0011 19.0 0.1 2.7 2 0 0 2 2 2 2 Sigma-70 region 3 HAD_2 PF13419.6 KXZ44295.1 - 1.8e-09 37.9 0.0 2.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ44295.1 - 1.9e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXZ44295.1 - 0.00044 20.6 0.0 0.00079 19.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pyr_redox_3 PF13738.6 KXZ44295.1 - 0.078 12.2 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PTS_2-RNA PF01885.16 KXZ44296.1 - 3.6e-38 131.4 0.0 4.2e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF5338 PF17273.2 KXZ44296.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5338) DUF1168 PF06658.12 KXZ44297.1 - 7.4e-30 103.5 13.8 9e-30 103.3 13.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Amidase PF01425.21 KXZ44297.1 - 0.0022 17.0 1.9 0.0028 16.7 1.9 1.0 1 0 0 1 1 1 1 Amidase RisS_PPD PF16524.5 KXZ44297.1 - 0.024 14.9 0.2 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS DUF1823 PF08853.11 KXZ44297.1 - 0.033 14.4 2.4 0.048 13.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) GAGA_bind PF06217.12 KXZ44297.1 - 0.15 12.3 5.8 0.15 12.3 5.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 KXZ44297.1 - 1.8 8.4 10.2 2 8.2 10.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 KXZ44297.1 - 2.4 7.5 7.0 2.8 7.2 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CSN5_C PF18323.1 KXZ44297.1 - 2.9 8.8 10.3 1 10.3 0.8 2.1 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Sec62 PF03839.16 KXZ44297.1 - 5.5 6.4 8.8 7.1 6.1 8.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 mTERF PF02536.14 KXZ44299.1 - 0.034 13.1 0.0 0.064 12.2 0.0 1.4 1 1 0 1 1 1 0 mTERF PAXNEB PF05625.11 KXZ44300.1 - 0.00011 21.5 0.0 0.00038 19.7 0.0 1.7 2 0 0 2 2 2 1 PAXNEB protein Abhydrolase_1 PF00561.20 KXZ44301.1 - 2.3e-08 34.0 0.4 1.8e-07 31.1 0.3 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ44301.1 - 2.1e-06 27.2 0.2 1.5e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KXZ44301.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Glyco_hydro_31 PF01055.26 KXZ44302.1 - 1.5e-30 106.8 0.0 1.7e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXZ44302.1 - 1.7e-08 34.7 0.1 4.4e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.26 KXZ44303.1 - 3.2e-86 290.2 0.0 5.4e-86 289.5 0.0 1.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 GMP_synt_C PF00958.22 KXZ44305.1 - 3.2e-41 139.3 0.0 6.2e-41 138.4 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KXZ44305.1 - 3e-30 105.4 0.1 4.3e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXZ44305.1 - 2.3e-13 50.4 0.0 4.3e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 KXZ44305.1 - 3.9e-08 32.7 0.0 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.14 KXZ44305.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 KXZ44305.1 - 0.0061 15.4 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 KXZ44305.1 - 0.015 14.8 0.0 0.086 12.3 0.0 2.2 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KXZ44305.1 - 0.057 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family SNO PF01174.19 KXZ44305.1 - 0.065 13.1 0.0 0.32 10.8 0.0 2.1 1 1 0 1 1 1 0 SNO glutamine amidotransferase family ATP_bind_3 PF01171.20 KXZ44305.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LRR_9 PF14580.6 KXZ44306.1 - 3.4e-16 59.2 2.0 9.2e-08 31.8 0.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KXZ44306.1 - 5.4e-15 55.3 14.5 8.4e-08 32.4 0.3 3.8 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ44306.1 - 4.8e-12 45.5 10.5 1.8e-05 24.4 1.1 3.8 3 1 0 3 3 3 2 Leucine rich repeat PBECR4 PF18813.1 KXZ44306.1 - 0.035 14.3 0.9 0.73 10.0 0.1 2.3 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 Rrn6 PF10214.9 KXZ44306.1 - 0.21 10.0 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1118 PF06549.12 KXZ44306.1 - 0.43 10.9 2.2 1.5 9.2 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1118) LRR_1 PF00560.33 KXZ44306.1 - 6.3 7.8 15.1 36 5.5 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KXZ44306.1 - 8.4 6.7 9.1 1.1e+02 3.2 0.0 4.7 5 1 1 6 6 6 0 Leucine Rich repeat FtsJ PF01728.19 KXZ44308.1 - 2.8e-31 109.0 0.0 7e-25 88.1 0.0 2.5 3 0 0 3 3 3 2 FtsJ-like methyltransferase G-patch PF01585.23 KXZ44308.1 - 5.8e-11 42.1 1.4 5.8e-11 42.1 1.4 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXZ44308.1 - 0.11 12.6 3.9 0.08 13.1 0.9 2.4 2 0 0 2 2 2 0 G-patch domain Robl_LC7 PF03259.17 KXZ44308.1 - 0.92 9.3 4.6 0.87 9.4 0.1 2.8 2 0 0 2 2 2 0 Roadblock/LC7 domain TPH PF13868.6 KXZ44309.1 - 1.3e-76 257.4 146.2 1.3e-76 257.4 146.2 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RITA PF17066.5 KXZ44309.1 - 0.038 13.6 0.1 0.038 13.6 0.1 2.4 2 1 0 3 3 3 0 RBPJ-interacting and tubulin associated protein DUF2740 PF10872.8 KXZ44309.1 - 0.041 13.8 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Coprogen_oxidas PF01218.18 KXZ44310.1 - 4e-102 340.9 0.0 4.7e-102 340.7 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TPR_2 PF07719.17 KXZ44311.1 - 5.1e-08 32.5 7.1 0.0015 18.5 0.5 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ44311.1 - 5.5e-07 29.6 2.5 6.1e-06 26.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ44311.1 - 2e-06 27.3 3.3 0.13 12.2 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ44311.1 - 0.003 17.2 0.8 0.56 9.9 0.3 2.6 2 0 0 2 2 2 1 TPR repeat Phage_TAC_7 PF10109.9 KXZ44311.1 - 0.0093 16.1 10.9 13 5.9 0.7 5.2 4 1 0 4 4 4 0 Phage tail assembly chaperone proteins, E, or 41 or 14 TPR_8 PF13181.6 KXZ44311.1 - 0.042 14.1 0.8 5.1 7.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ44311.1 - 0.068 13.2 0.8 21 5.4 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ44311.1 - 0.15 12.8 0.0 0.15 12.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ44311.1 - 0.15 13.0 10.2 10 7.2 0.0 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ44311.1 - 0.35 11.2 10.1 0.38 11.1 0.6 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Skp1 PF01466.19 KXZ44311.1 - 2.7 8.2 20.9 3.4 7.9 0.6 5.8 6 1 1 7 7 7 0 Skp1 family, dimerisation domain EH_Signature PF15611.6 KXZ44311.1 - 3.3 7.0 8.2 0.089 12.2 1.4 1.9 2 1 0 2 2 2 0 EH_Signature domain MCU PF04678.13 KXZ44311.1 - 4.7 7.3 8.9 0.88 9.6 0.1 3.3 2 1 1 3 3 3 0 Mitochondrial calcium uniporter FliG_N PF14842.6 KXZ44311.1 - 4.8 7.8 0.0 4.8 7.8 0.0 7.7 6 2 0 6 6 6 0 FliG N-terminal domain UPF1_Zn_bind PF09416.10 KXZ44312.1 - 4.2e-62 208.6 0.1 6.4e-61 204.8 0.0 2.6 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KXZ44312.1 - 1e-57 195.0 0.0 1.5e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ44312.1 - 1.8e-47 162.4 1.4 7.5e-27 94.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KXZ44312.1 - 4.5e-27 94.1 0.0 9.7e-27 93.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KXZ44312.1 - 2.1e-14 53.7 0.2 2.1e-14 53.7 0.2 2.5 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KXZ44312.1 - 6.6e-12 46.0 0.1 1.5e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXZ44312.1 - 2.8e-05 24.2 0.0 5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KXZ44312.1 - 0.0004 20.2 0.3 0.29 10.9 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KXZ44312.1 - 0.00086 19.1 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KXZ44312.1 - 0.001 18.4 0.1 0.017 14.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KXZ44312.1 - 0.0025 17.7 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Helicase Ribosomal_S13_N PF08069.12 KXZ44312.1 - 0.0089 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain ATPase PF06745.13 KXZ44312.1 - 0.0098 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC UvrD-helicase PF00580.21 KXZ44312.1 - 0.019 14.5 0.1 0.36 10.3 0.0 2.4 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KXZ44312.1 - 0.03 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.14 KXZ44312.1 - 0.03 13.5 0.0 2.6 7.1 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase SRP54 PF00448.22 KXZ44312.1 - 0.033 13.8 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KXZ44312.1 - 0.05 13.9 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXZ44312.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTF2 PF02136.20 KXZ44314.1 - 9.3e-19 68.2 0.1 1.3e-18 67.7 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain p450 PF00067.22 KXZ44315.1 - 2.2e-69 234.4 0.0 2.7e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PCO_ADO PF07847.12 KXZ44316.1 - 5.4e-49 166.4 0.0 6e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 KXZ44316.1 - 0.015 15.0 0.0 0.081 12.6 0.0 2.0 2 0 0 2 2 2 0 Cupin domain CDO_I PF05995.12 KXZ44316.1 - 0.047 13.0 0.0 0.056 12.7 0.0 1.3 1 1 0 1 1 1 0 Cysteine dioxygenase type I PQQ_2 PF13360.6 KXZ44317.1 - 3e-22 79.4 12.3 9.8e-10 38.4 0.9 3.6 2 1 1 3 3 3 3 PQQ-like domain TPR_2 PF07719.17 KXZ44317.1 - 2.2e-11 43.0 6.7 4.2e-06 26.5 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ44317.1 - 6.4e-11 42.6 4.9 4.3e-08 33.6 0.3 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ44317.1 - 9.8e-11 41.0 6.3 1e-05 25.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ44317.1 - 1.8e-10 40.3 4.6 0.00029 20.5 0.1 3.7 2 1 1 3 3 3 3 TPR repeat PQQ PF01011.21 KXZ44317.1 - 2.3e-09 36.7 5.3 0.091 12.7 0.0 7.8 8 0 0 8 8 8 1 PQQ enzyme repeat TPR_8 PF13181.6 KXZ44317.1 - 1.3e-06 28.2 2.5 6.8e-05 22.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ44317.1 - 9.9e-06 25.6 0.3 5.8e-05 23.2 0.3 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ44317.1 - 5.4e-05 23.7 0.9 5.4e-05 23.7 0.9 4.6 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ44317.1 - 0.0001 22.4 2.2 0.28 11.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ44317.1 - 0.00041 20.8 3.2 0.005 17.4 0.1 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ44317.1 - 0.001 19.6 0.1 0.001 19.6 0.1 6.2 7 0 0 7 7 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ44317.1 - 0.0024 17.9 0.2 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KXZ44317.1 - 0.0043 17.2 1.1 0.016 15.4 1.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXZ44317.1 - 0.0096 16.2 7.3 0.019 15.3 1.1 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ44317.1 - 0.014 15.4 7.9 1.4 9.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ44317.1 - 0.14 12.5 5.8 0.15 12.4 1.2 3.3 2 1 2 4 4 3 0 Tetratricopeptide repeat HEPN PF05168.14 KXZ44317.1 - 0.3 11.2 3.1 14 5.9 0.6 2.4 2 0 0 2 2 2 0 HEPN domain Aha1_N PF09229.11 KXZ44318.1 - 1e-24 87.3 0.0 1.7e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KXZ44318.1 - 4.6e-15 56.0 0.0 1.2e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein LRR_8 PF13855.6 KXZ44319.1 - 9e-38 127.9 51.9 2.4e-09 36.8 2.2 6.3 2 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KXZ44319.1 - 5.7e-37 125.1 28.8 3.3e-06 27.3 0.4 8.3 2 2 6 10 10 10 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXZ44319.1 - 5.6e-07 29.2 9.6 0.63 9.5 0.3 5.0 1 1 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 KXZ44319.1 - 0.00016 21.7 30.5 10 7.1 0.1 11.0 11 1 0 11 11 11 2 Leucine Rich Repeat SAM_3 PF18016.1 KXZ44319.1 - 0.00039 20.2 0.6 0.26 11.1 0.1 3.7 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) CREPT PF16566.5 KXZ44319.1 - 0.24 11.6 1.4 47 4.1 0.0 3.9 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour LRRNT PF01462.18 KXZ44319.1 - 1.8 8.3 5.1 1.4e+02 2.2 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat N-terminal domain HXXSHH PF07586.11 KXZ44321.1 - 0.027 14.1 5.5 0.046 13.3 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) HrcA PF01628.21 KXZ44321.1 - 1.1 9.1 4.9 2.3 8.1 4.9 1.5 1 0 0 1 1 1 0 HrcA protein C terminal domain PRP3 PF08572.10 KXZ44321.1 - 2.6 7.7 12.9 0.81 9.4 1.2 2.3 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Whirly PF08536.11 KXZ44322.1 - 3.9e-29 101.2 0.0 4.5e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Whirly transcription factor ZapA PF05164.13 KXZ44324.1 - 9 6.8 11.9 6 7.4 6.7 2.9 2 1 1 3 3 3 0 Cell division protein ZapA ECH_1 PF00378.20 KXZ44325.1 - 1.9e-62 210.8 0.0 2.6e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXZ44325.1 - 1.4e-30 106.9 0.0 7.5e-28 98.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 KXZ44325.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF1126 PF06565.12 KXZ44327.1 - 7.3e-101 331.1 4.5 9.6e-35 118.6 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 KXZ44327.1 - 0.00034 21.0 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ44327.1 - 0.0012 18.2 0.7 0.0085 15.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXZ44327.1 - 0.015 15.2 0.0 0.078 13.0 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KXZ44327.1 - 0.22 11.1 1.1 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 EF hand PDZ_3 PF17815.1 KXZ44328.1 - 3e-53 179.6 0.0 4.7e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KXZ44328.1 - 5.2e-16 59.9 3.8 2.8e-15 57.5 3.8 2.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KXZ44328.1 - 1.5e-08 34.8 0.0 6.1e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 KXZ44328.1 - 8.3e-07 29.0 1.2 5.8e-06 26.3 1.2 2.0 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KXZ44328.1 - 0.0013 18.5 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KXZ44328.1 - 0.0018 18.6 0.0 0.065 13.6 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_1 PF12812.7 KXZ44328.1 - 0.0053 16.8 0.0 1.1 9.4 0.0 2.8 2 0 0 2 2 2 1 PDZ-like domain Mito_carr PF00153.27 KXZ44329.1 - 1.9e-47 159.1 8.7 1.8e-18 66.2 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein AAA_lid_9 PF17871.1 KXZ44332.1 - 3.4e-23 81.5 0.3 6.4e-23 80.7 0.3 1.5 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 KXZ44332.1 - 1.1e-20 74.4 0.0 2.5e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KXZ44332.1 - 6.4e-19 68.7 0.0 6.3e-16 59.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXZ44332.1 - 1.4e-09 38.6 8.3 0.001 19.5 0.1 4.7 3 2 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KXZ44332.1 - 3.1e-09 37.0 0.0 0.00085 19.3 0.0 3.5 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ44332.1 - 9e-08 32.5 0.1 0.042 14.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXZ44332.1 - 1.4e-05 25.7 0.1 0.0085 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXZ44332.1 - 2.3e-05 23.7 0.0 0.071 12.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 KXZ44332.1 - 2.6e-05 24.2 0.0 0.053 13.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 KXZ44332.1 - 2.8e-05 23.9 0.8 0.072 12.8 0.0 3.7 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXZ44332.1 - 6.3e-05 23.2 0.0 0.16 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ44332.1 - 0.00012 22.4 0.0 0.21 12.0 0.0 3.2 3 0 0 3 3 3 1 RNA helicase TniB PF05621.11 KXZ44332.1 - 0.00019 20.9 0.0 1.9 7.8 0.0 3.3 2 1 1 3 3 3 1 Bacterial TniB protein Sigma54_activat PF00158.26 KXZ44332.1 - 0.00026 20.7 0.1 0.0092 15.7 0.1 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXZ44332.1 - 0.00031 20.5 0.0 0.84 9.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 KXZ44332.1 - 0.00089 19.3 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KXZ44332.1 - 0.0011 18.4 0.0 0.69 9.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXZ44332.1 - 0.0013 19.0 2.2 0.22 11.8 0.0 3.7 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KXZ44332.1 - 0.0021 18.0 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 KXZ44332.1 - 0.0021 17.6 0.0 1.3 8.6 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 KXZ44332.1 - 0.0024 17.8 0.0 7 6.5 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KXZ44332.1 - 0.0028 18.2 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KXZ44332.1 - 0.0035 17.1 0.0 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXZ44332.1 - 0.007 15.7 0.1 0.25 10.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 KXZ44332.1 - 0.0078 15.9 10.8 0.68 9.6 0.1 3.9 3 0 0 3 3 3 1 AAA domain zf-NADH-PPase PF09297.11 KXZ44332.1 - 0.0091 15.6 1.8 0.029 14.0 1.8 1.9 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Roc PF08477.13 KXZ44332.1 - 0.011 16.0 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KXZ44332.1 - 0.011 15.3 0.3 2.3 7.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXZ44332.1 - 0.012 15.5 0.0 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 KXZ44332.1 - 0.015 14.5 0.0 1.8 7.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.6 KXZ44332.1 - 0.016 15.7 0.3 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXZ44332.1 - 0.035 14.5 0.1 15 5.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 KXZ44332.1 - 0.039 13.9 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MCM PF00493.23 KXZ44332.1 - 0.049 12.7 0.0 0.57 9.2 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain PduV-EutP PF10662.9 KXZ44332.1 - 0.06 13.1 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 KXZ44332.1 - 0.11 12.5 0.0 6.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KXZ44332.1 - 0.12 11.5 0.1 24 4.0 0.0 2.8 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_24 PF13479.6 KXZ44332.1 - 0.13 11.9 0.0 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zn_Tnp_IS1595 PF12760.7 KXZ44332.1 - 0.15 12.1 0.8 0.41 10.7 0.8 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain ATP_bind_1 PF03029.17 KXZ44332.1 - 0.15 11.8 0.0 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zinc_ribbon_9 PF14369.6 KXZ44332.1 - 0.18 12.1 1.9 18 5.7 0.0 2.5 1 1 1 2 2 2 0 zinc-ribbon MMR_HSR1 PF01926.23 KXZ44332.1 - 0.2 11.8 0.0 9.2 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase OrfB_Zn_ribbon PF07282.11 KXZ44332.1 - 0.24 11.3 0.8 0.61 10.0 0.8 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_5 PF13719.6 KXZ44332.1 - 0.39 10.5 1.5 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KXZ44332.1 - 0.48 10.5 4.6 0.096 12.7 0.6 1.8 2 0 0 2 2 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 KXZ44332.1 - 0.87 9.6 2.9 3.2 7.7 0.1 2.7 1 1 1 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KXZ44332.1 - 0.93 9.5 7.3 1.2 9.1 4.8 2.4 2 0 0 2 2 2 0 Nudix N-terminal YqzE PF14038.6 KXZ44332.1 - 1.4 8.9 2.5 43 4.2 0.2 2.4 2 0 0 2 2 2 0 YqzE-like protein S4 PF01479.25 KXZ44333.1 - 0.00084 19.0 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 S4 domain Glyco_trans_1_4 PF13692.6 KXZ44333.1 - 0.075 13.5 1.0 2.3 8.6 0.0 2.3 1 1 1 2 2 2 0 Glycosyl transferases group 1 DUF1269 PF06897.12 KXZ44334.1 - 0.099 12.9 0.4 0.18 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) CytochromB561_N PF09786.9 KXZ44334.1 - 0.36 9.8 14.4 0.4 9.6 14.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SOG2 PF10428.9 KXZ44334.1 - 0.39 9.9 15.6 0.43 9.7 15.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KXZ44334.1 - 0.42 10.5 11.0 0.51 10.2 11.0 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 KXZ44334.1 - 0.98 7.9 3.4 1 7.8 3.4 1.1 1 0 0 1 1 1 0 Macoilin family PRCC PF10253.9 KXZ44334.1 - 4.7 8.0 11.9 3.2 8.5 10.5 1.4 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Apt1 PF10351.9 KXZ44334.1 - 5.5 5.7 6.5 6.4 5.5 6.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Iwr1 PF08574.10 KXZ44335.1 - 9.8e-10 39.3 5.4 9.8e-10 39.3 5.4 3.3 3 1 0 3 3 3 1 Transcription factor Iwr1 MRP-63 PF14978.6 KXZ44335.1 - 0.14 12.8 0.2 0.29 11.8 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 Pkinase_Tyr PF07714.17 KXZ44336.1 - 8.9e-54 182.5 0.0 1.2e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ44336.1 - 3.8e-51 174.0 0.0 4.9e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ44336.1 - 0.00011 22.2 0.2 0.0091 15.9 0.0 3.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ44336.1 - 0.0015 17.5 0.0 0.0043 16.0 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain DUF3357 PF11837.8 KXZ44336.1 - 0.11 13.0 0.2 0.29 11.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Kinase-like PF14531.6 KXZ44336.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KXZ44337.1 - 8.4e-48 163.0 0.0 1.3e-47 162.4 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44337.1 - 6.6e-21 74.7 0.0 1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ44337.1 - 2.5e-05 23.7 0.0 7.7e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ44337.1 - 3.9e-05 23.7 0.1 0.0001 22.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ44337.1 - 0.032 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ44337.1 - 0.062 12.1 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KXZ44337.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KXZ44337.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KXZ44337.1 - 0.24 10.3 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain AAA_2 PF07724.14 KXZ44338.1 - 1.1e-58 198.2 0.0 2.6e-55 187.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXZ44338.1 - 2.3e-33 114.2 3.6 5.4e-32 109.8 0.3 2.8 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 KXZ44338.1 - 1.8e-25 89.9 0.0 6.7e-14 52.5 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXZ44338.1 - 4.1e-25 87.6 0.7 2e-24 85.4 0.7 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 KXZ44338.1 - 1.6e-24 85.8 0.5 2.8e-11 43.3 0.0 3.5 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KXZ44338.1 - 1.9e-18 66.8 0.1 1.5e-12 47.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ44338.1 - 1.1e-12 48.6 9.9 0.00011 22.7 0.1 5.5 4 2 1 5 5 4 3 AAA ATPase domain AAA_22 PF13401.6 KXZ44338.1 - 2.2e-09 37.7 2.4 0.018 15.3 0.0 5.6 3 2 0 4 4 4 2 AAA domain Sigma54_activat PF00158.26 KXZ44338.1 - 7.9e-09 35.4 0.0 5.3e-06 26.2 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXZ44338.1 - 9.7e-07 28.7 0.0 0.035 13.8 0.0 3.0 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 KXZ44338.1 - 2.4e-06 27.1 0.0 0.0059 16.0 0.0 4.1 3 1 0 3 3 3 1 Bacterial TniB protein AAA_18 PF13238.6 KXZ44338.1 - 2.5e-05 24.8 0.1 0.13 12.8 0.0 3.5 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KXZ44338.1 - 2.8e-05 23.6 0.2 0.22 10.9 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KXZ44338.1 - 3.1e-05 24.0 0.0 0.3 11.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXZ44338.1 - 6.7e-05 22.5 0.0 0.086 12.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 KXZ44338.1 - 6.8e-05 23.2 1.0 4.1 7.6 0.0 4.4 4 1 0 4 4 3 1 AAA domain ATPase_2 PF01637.18 KXZ44338.1 - 6.8e-05 22.9 0.2 4.6 7.1 0.0 4.3 3 1 0 4 4 4 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KXZ44338.1 - 0.0001 22.2 0.0 0.12 12.2 0.0 3.2 2 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KXZ44338.1 - 0.00026 21.1 0.2 0.36 11.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KXZ44338.1 - 0.00035 20.3 0.0 0.66 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXZ44338.1 - 0.00048 20.5 0.1 1.2 9.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase RuvB_N PF05496.12 KXZ44338.1 - 0.00094 19.0 2.9 1.1 9.0 0.0 3.8 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 KXZ44338.1 - 0.0011 19.1 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KXZ44338.1 - 0.0012 18.2 0.0 0.14 11.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 KXZ44338.1 - 0.0015 18.5 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KXZ44338.1 - 0.0022 17.8 0.1 2.3 8.1 0.1 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KXZ44338.1 - 0.0035 17.9 0.5 0.7 10.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KXZ44338.1 - 0.0037 17.2 0.0 4.8 7.1 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase ResIII PF04851.15 KXZ44338.1 - 0.0043 17.1 0.0 0.76 9.8 0.0 3.6 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KXZ44338.1 - 0.012 16.2 0.0 0.93 10.0 0.0 2.8 2 0 0 2 2 2 0 ABC transporter DNA_pol3_delta2 PF13177.6 KXZ44338.1 - 0.02 14.7 0.0 0.32 10.8 0.0 2.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 KXZ44338.1 - 0.031 14.6 0.1 1.2 9.5 0.2 3.2 3 1 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KXZ44338.1 - 0.047 13.3 0.0 2 7.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KXZ44338.1 - 0.048 12.8 0.0 1.9 7.6 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Torsin PF06309.11 KXZ44338.1 - 0.055 13.6 0.0 0.25 11.4 0.0 2.1 3 0 0 3 3 1 0 Torsin SRP54 PF00448.22 KXZ44338.1 - 0.076 12.6 0.1 2.6 7.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FlxA PF14282.6 KXZ44338.1 - 0.096 12.7 1.6 0.43 10.6 0.1 2.4 1 1 1 2 2 2 0 FlxA-like protein NTPase_1 PF03266.15 KXZ44338.1 - 0.14 12.1 0.2 13 5.6 0.0 2.8 3 0 0 3 3 2 0 NTPase PduV-EutP PF10662.9 KXZ44338.1 - 0.15 11.8 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation BST2 PF16716.5 KXZ44338.1 - 0.78 10.4 6.4 3.2 8.4 0.8 3.9 4 0 0 4 4 4 0 Bone marrow stromal antigen 2 DUF1192 PF06698.11 KXZ44338.1 - 1.4 9.0 6.1 2.9 8.0 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) zf-MYND PF01753.18 KXZ44339.1 - 2.1e-09 37.3 4.4 4.5e-09 36.2 4.4 1.6 1 0 0 1 1 1 1 MYND finger DUF747 PF05346.11 KXZ44340.1 - 3.2e-53 181.3 0.0 4.2e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Ank_2 PF12796.7 KXZ44342.1 - 5.1e-06 27.0 0.8 0.0051 17.4 0.0 3.8 3 2 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44342.1 - 1.3e-05 25.7 1.6 3.4 8.4 0.8 5.2 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44342.1 - 0.027 15.0 0.0 2.8e+02 2.6 0.0 5.0 5 0 0 5 5 5 0 Ankyrin repeat Cut8 PF08559.10 KXZ44342.1 - 0.036 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Syja_N PF02383.18 KXZ44343.1 - 1.2e-66 225.3 0.0 1.6e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain UBA PF00627.31 KXZ44344.1 - 7.2e-08 32.2 0.1 2.3e-07 30.6 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EcoEI_R_C PF08463.10 KXZ44344.1 - 0.025 14.7 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 EcoEI R protein C-terminal Plasmid_stab_B PF10784.9 KXZ44344.1 - 0.28 11.1 3.2 1.1 9.1 0.5 2.5 2 0 0 2 2 2 0 Plasmid stability protein PCMT PF01135.19 KXZ44345.1 - 2.1e-50 171.4 0.1 2.5e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXZ44345.1 - 2.4e-05 23.9 0.1 3.2e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXZ44345.1 - 2.8e-05 24.0 0.0 3.9e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXZ44345.1 - 4.3e-05 23.5 0.0 5.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ44345.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ44345.1 - 0.00073 20.2 0.1 0.0017 19.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXZ44345.1 - 0.0039 18.2 0.2 0.012 16.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44345.1 - 0.0054 17.3 0.2 0.021 15.5 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KXZ44345.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KXZ44345.1 - 0.024 14.2 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ACP_syn_III_C PF08541.10 KXZ44345.1 - 0.089 13.0 1.5 0.22 11.7 0.0 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CMAS PF02353.20 KXZ44345.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase YGGT PF02325.17 KXZ44346.1 - 4.9e-17 62.1 2.2 8.2e-17 61.4 2.2 1.4 1 0 0 1 1 1 1 YGGT family SapB_2 PF03489.17 KXZ44347.1 - 9.7e-22 76.8 3.8 9.9e-08 32.0 0.3 3.9 3 0 0 3 3 3 3 Saposin-like type B, region 2 SapB_1 PF05184.15 KXZ44347.1 - 8.8e-14 51.2 7.5 7.1e-07 29.1 0.1 3.5 3 0 0 3 3 3 2 Saposin-like type B, region 1 DUF3456 PF11938.8 KXZ44347.1 - 0.36 11.3 1.5 20 5.7 0.1 3.1 3 1 1 4 4 4 0 TLR4 regulator and MIR-interacting MSAP zf-MYND PF01753.18 KXZ44350.1 - 2.8e-08 33.7 9.2 1.1e-07 31.9 9.2 2.1 1 0 0 1 1 1 1 MYND finger CK2S PF15011.6 KXZ44351.1 - 8.6e-10 38.7 0.1 1e-09 38.5 0.1 1.1 1 0 0 1 1 1 1 Casein Kinase 2 substrate DUF3721 PF12518.8 KXZ44351.1 - 0.27 11.1 0.2 0.27 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function zf-MYND PF01753.18 KXZ44352.1 - 0.017 15.2 9.0 0.042 14.0 9.0 1.6 1 0 0 1 1 1 0 MYND finger zf-MYND PF01753.18 KXZ44353.1 - 6.7e-08 32.5 8.8 1.7e-07 31.2 8.8 1.7 1 0 0 1 1 1 1 MYND finger NT-C2 PF10358.9 KXZ44354.1 - 2.1e-10 40.5 0.1 3.2e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CDI PF02234.19 KXZ44354.1 - 0.065 13.4 0.0 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Aldedh PF00171.22 KXZ44355.1 - 6e-143 476.7 0.2 7e-143 476.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ANAPC4 PF12896.7 KXZ44356.1 - 4e-28 98.3 0.0 5.5e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KXZ44356.1 - 2.3e-25 88.7 0.0 3.9e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ44356.1 - 0.066 14.1 7.0 0.18 12.7 0.2 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat DHHC PF01529.20 KXZ44357.1 - 3.5e-24 85.4 0.7 5.3e-24 84.8 0.7 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Pantoate_ligase PF02569.15 KXZ44358.1 - 6.3e-88 294.4 0.0 1.3e-55 188.5 0.0 2.0 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase LCAT PF02450.15 KXZ44361.1 - 4.3e-21 75.5 0.0 2.2e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase APG12 PF04110.13 KXZ44362.1 - 1.5e-21 76.6 0.0 1.6e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KXZ44362.1 - 0.035 14.3 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Mre11_DNA_bind PF04152.14 KXZ44363.1 - 4e-29 102.1 0.0 9.1e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KXZ44363.1 - 5.8e-09 36.8 0.0 8.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ44363.1 - 0.0029 17.8 0.0 0.0083 16.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PBP1_TM PF14812.6 KXZ44363.1 - 0.17 12.3 3.5 0.48 10.8 3.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KXZ44363.1 - 0.22 10.8 5.3 0.33 10.2 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 KXZ44363.1 - 0.47 10.3 3.7 0.81 9.5 3.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 KXZ44363.1 - 3.1 5.9 4.9 4.1 5.5 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family adh_short PF00106.25 KXZ44364.1 - 6.2e-26 91.1 0.0 1.6e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ44364.1 - 2.6e-16 59.9 0.1 3.7e-16 59.4 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ44364.1 - 6.9e-09 35.9 0.6 1.1e-08 35.3 0.6 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXZ44364.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DASH_Spc19 PF08287.11 KXZ44366.1 - 0.016 15.1 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 Spc19 PspA_IM30 PF04012.12 KXZ44366.1 - 0.02 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 PspA/IM30 family DUF1664 PF07889.12 KXZ44366.1 - 0.025 14.6 0.2 0.044 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc42p PF11544.8 KXZ44366.1 - 0.028 14.4 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF948 PF06103.11 KXZ44366.1 - 0.035 14.3 0.3 0.07 13.4 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4618 PF15397.6 KXZ44366.1 - 0.052 13.0 0.2 0.073 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) LPP PF04728.13 KXZ44366.1 - 0.063 13.7 0.3 0.063 13.7 0.3 2.0 2 1 0 2 2 1 0 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 KXZ44366.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Tropomyosin like Tektin PF03148.14 KXZ44366.1 - 0.12 11.1 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Tektin family BLOC1_2 PF10046.9 KXZ44366.1 - 0.15 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4795 PF16043.5 KXZ44366.1 - 0.15 11.6 0.2 0.55 9.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FlaC_arch PF05377.11 KXZ44366.1 - 0.16 12.4 0.2 0.33 11.4 0.2 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2207 PF09972.9 KXZ44366.1 - 0.17 10.6 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GIT_SHD PF08518.11 KXZ44366.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT BLOC1_2 PF10046.9 KXZ44367.1 - 1e-09 38.6 0.5 4.3e-05 23.7 0.5 3.5 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KXZ44367.1 - 1.8e-09 37.8 6.3 1.7e-07 31.4 6.5 2.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 KXZ44367.1 - 9.1e-09 34.5 0.4 1.3e-08 34.0 0.4 1.1 1 0 0 1 1 1 1 AAA domain FlaC_arch PF05377.11 KXZ44367.1 - 9.7e-09 35.5 12.4 0.0019 18.6 2.0 3.6 1 1 2 3 3 3 3 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KXZ44367.1 - 1.4e-07 32.0 3.8 2.4e-07 31.2 3.8 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CLZ PF16526.5 KXZ44367.1 - 1.5e-07 31.6 0.7 0.0093 16.3 0.0 3.1 1 1 2 3 3 3 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KXZ44367.1 - 3.4e-07 30.3 7.3 0.00081 19.4 2.3 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DASH_Spc19 PF08287.11 KXZ44367.1 - 4.3e-07 29.9 14.3 0.063 13.2 1.5 4.0 1 1 2 3 3 3 3 Spc19 SlyX PF04102.12 KXZ44367.1 - 5.3e-07 30.2 0.0 0.0034 18.0 0.0 2.7 1 1 1 2 2 2 2 SlyX Myosin_tail_1 PF01576.19 KXZ44367.1 - 6.9e-07 27.5 5.2 8.8e-07 27.2 5.2 1.1 1 0 0 1 1 1 1 Myosin tail PspA_IM30 PF04012.12 KXZ44367.1 - 8.8e-07 28.7 0.9 0.024 14.2 0.1 2.6 1 1 1 2 2 2 2 PspA/IM30 family CENP-F_leu_zip PF10473.9 KXZ44367.1 - 9.6e-07 28.9 7.6 2.5e-06 27.5 6.0 2.4 2 1 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 KXZ44367.1 - 1e-06 29.0 3.7 0.0013 18.9 1.9 2.6 1 1 1 2 2 2 2 Tropomyosin like DUF4795 PF16043.5 KXZ44367.1 - 1e-06 28.5 1.3 2.4e-06 27.3 1.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) DUF812 PF05667.11 KXZ44367.1 - 1.6e-06 27.4 1.5 8.3e-06 25.0 1.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF812) DUF2730 PF10805.8 KXZ44367.1 - 1.6e-06 28.1 15.5 0.0012 18.9 1.5 2.9 1 1 3 4 4 4 3 Protein of unknown function (DUF2730) ADIP PF11559.8 KXZ44367.1 - 2.1e-06 27.9 1.8 0.0075 16.4 1.4 2.4 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KXZ44367.1 - 2.1e-06 27.6 4.3 0.089 12.8 0.4 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding Vps53_N PF04100.12 KXZ44367.1 - 3.3e-06 26.3 2.2 6.8e-06 25.3 2.2 1.5 1 1 0 1 1 1 1 Vps53-like, N-terminal Lzipper-MIP1 PF14389.6 KXZ44367.1 - 3.4e-06 27.3 4.0 0.12 12.6 0.1 4.0 1 1 2 3 3 2 2 Leucine-zipper of ternary complex factor MIP1 Trimer_CC PF08954.11 KXZ44367.1 - 4.7e-06 26.0 0.3 0.17 11.4 0.0 3.8 1 1 2 3 3 3 2 Trimerisation motif DUF948 PF06103.11 KXZ44367.1 - 5.9e-06 26.5 4.7 0.0038 17.5 0.2 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KXZ44367.1 - 6.4e-06 26.4 10.6 3.4e-05 24.1 3.1 2.2 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KXZ44367.1 - 8e-06 24.9 1.8 1.2e-05 24.4 1.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein FPP PF05911.11 KXZ44367.1 - 1e-05 24.0 3.1 1.3e-05 23.6 3.1 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF5082 PF16888.5 KXZ44367.1 - 1.5e-05 25.2 6.7 0.0073 16.6 1.6 2.9 1 1 2 3 3 2 2 Domain of unknown function (DUF5082) Laminin_II PF06009.12 KXZ44367.1 - 1.6e-05 24.9 8.8 0.00023 21.2 5.4 2.2 1 1 1 2 2 2 1 Laminin Domain II Prominin PF05478.11 KXZ44367.1 - 1.7e-05 23.1 3.8 0.00016 19.8 3.5 2.0 1 1 0 1 1 1 1 Prominin EzrA PF06160.12 KXZ44367.1 - 1.7e-05 23.2 1.6 3e-05 22.4 1.6 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CorA PF01544.18 KXZ44367.1 - 1.9e-05 24.2 1.5 0.25 10.6 2.5 3.0 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Tektin PF03148.14 KXZ44367.1 - 2.6e-05 23.2 6.8 0.012 14.4 1.4 3.0 1 1 2 3 3 3 2 Tektin family bZIP_1 PF00170.21 KXZ44367.1 - 3.1e-05 24.0 2.3 0.4 10.8 0.2 3.7 1 1 3 4 4 4 1 bZIP transcription factor ZapB PF06005.12 KXZ44367.1 - 3.8e-05 24.1 0.5 0.031 14.7 0.5 2.7 1 1 0 1 1 1 1 Cell division protein ZapB NPV_P10 PF05531.12 KXZ44367.1 - 4.5e-05 23.8 5.7 0.07 13.6 0.4 3.2 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Vps51 PF08700.11 KXZ44367.1 - 4.5e-05 23.4 2.9 2.1 8.5 0.1 3.9 1 1 3 4 4 3 0 Vps51/Vps67 DUF745 PF05335.13 KXZ44367.1 - 5.4e-05 23.0 2.4 8.8e-05 22.3 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF745) TolA_bind_tri PF16331.5 KXZ44367.1 - 5.6e-05 23.1 4.4 0.0025 17.8 0.2 2.8 2 1 1 3 3 2 1 TolA binding protein trimerisation Lebercilin PF15619.6 KXZ44367.1 - 5.7e-05 22.9 1.9 0.00014 21.6 1.9 1.7 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 KXZ44367.1 - 6.3e-05 22.4 0.7 0.093 12.0 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) DUF16 PF01519.16 KXZ44367.1 - 8.9e-05 22.9 1.9 0.016 15.7 1.0 2.6 1 1 1 2 2 2 2 Protein of unknown function DUF16 SKA1 PF07160.12 KXZ44367.1 - 8.9e-05 22.4 5.1 0.0031 17.4 5.1 2.6 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF4618 PF15397.6 KXZ44367.1 - 9.1e-05 22.0 3.8 0.18 11.2 1.4 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Prefoldin_2 PF01920.20 KXZ44367.1 - 9.2e-05 22.4 0.2 0.9 9.5 0.0 3.0 1 1 2 3 3 3 1 Prefoldin subunit Cast PF10174.9 KXZ44367.1 - 9.6e-05 20.8 1.0 0.00011 20.6 1.0 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF4686 PF15742.5 KXZ44367.1 - 0.00011 21.5 3.2 0.0009 18.5 3.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4686) Med9 PF07544.13 KXZ44367.1 - 0.00012 22.1 0.2 0.00087 19.3 0.2 2.2 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin PF00261.20 KXZ44367.1 - 0.00012 21.5 0.9 0.0014 18.1 0.3 2.2 1 1 0 1 1 1 1 Tropomyosin TMCO5 PF14992.6 KXZ44367.1 - 0.00013 21.7 0.6 0.00026 20.7 0.6 1.5 1 0 0 1 1 1 1 TMCO5 family DUF4988 PF16378.5 KXZ44367.1 - 0.00013 21.7 5.0 0.27 10.9 0.9 3.8 1 1 2 3 3 3 1 Domain of unknown function DUF724 PF05266.14 KXZ44367.1 - 0.00015 21.6 1.6 0.00032 20.6 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF724) TMPIT PF07851.13 KXZ44367.1 - 0.00017 21.0 0.5 0.00026 20.4 0.5 1.2 1 0 0 1 1 1 1 TMPIT-like protein Cluap1 PF10234.9 KXZ44367.1 - 0.00017 21.1 1.3 0.12 11.8 0.2 2.3 1 1 1 2 2 2 2 Clusterin-associated protein-1 GP41 PF00517.17 KXZ44367.1 - 0.00018 21.4 1.1 0.48 10.3 0.2 2.8 1 1 1 2 2 2 1 Retroviral envelope protein XhlA PF10779.9 KXZ44367.1 - 0.00021 21.4 3.4 0.54 10.5 0.2 3.1 1 1 2 3 3 3 1 Haemolysin XhlA TACC_C PF05010.14 KXZ44367.1 - 0.00021 21.1 0.3 0.0004 20.2 0.3 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TMF_TATA_bd PF12325.8 KXZ44367.1 - 0.00021 21.5 6.4 0.22 11.8 4.3 2.5 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 KXZ44367.1 - 0.00024 20.1 0.2 0.00041 19.3 0.2 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.19 KXZ44367.1 - 0.00024 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.15 KXZ44367.1 - 0.00027 20.6 2.7 0.00041 20.0 2.7 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit GAS PF13851.6 KXZ44367.1 - 0.00028 20.3 1.9 0.00087 18.7 1.9 1.9 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 KXZ44367.1 - 0.00033 20.5 6.6 0.0066 16.2 6.2 2.0 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 YabA PF06156.13 KXZ44367.1 - 0.00033 21.2 5.0 0.77 10.4 3.5 3.3 1 1 2 3 3 3 1 Initiation control protein YabA Filament PF00038.21 KXZ44367.1 - 0.00034 20.3 3.3 0.0023 17.5 3.2 2.1 1 1 0 1 1 1 1 Intermediate filament protein Fez1 PF06818.15 KXZ44367.1 - 0.00038 21.0 4.6 0.0026 18.2 3.9 2.2 1 1 0 1 1 1 1 Fez1 Paralemmin PF03285.15 KXZ44367.1 - 0.0004 20.1 6.4 0.027 14.1 6.4 2.4 1 1 0 1 1 1 1 Paralemmin MAD PF05557.13 KXZ44367.1 - 0.00041 18.9 1.8 0.00073 18.0 1.8 1.4 1 0 0 1 1 1 1 Mitotic checkpoint protein KASH_CCD PF14662.6 KXZ44367.1 - 0.00046 20.1 7.4 0.0049 16.7 7.1 2.3 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Serine_rich PF08824.10 KXZ44367.1 - 0.00047 20.2 5.7 0.16 12.0 1.5 2.3 1 1 1 2 2 2 2 Serine rich protein interaction domain Syntaxin-6_N PF09177.11 KXZ44367.1 - 0.00052 20.5 4.1 0.11 13.1 4.1 3.2 1 1 0 1 1 1 1 Syntaxin 6, N-terminal PTRF_SDPR PF15237.6 KXZ44367.1 - 0.00078 19.1 6.6 0.017 14.8 1.7 2.2 1 1 1 2 2 2 1 PTRF/SDPR family Atg14 PF10186.9 KXZ44367.1 - 0.00078 18.6 0.5 0.0011 18.2 0.5 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 MIP-T3_C PF17749.1 KXZ44367.1 - 0.00081 19.4 1.2 3.6 7.5 0.1 3.4 1 1 2 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region TRAF_BIRC3_bd PF16673.5 KXZ44367.1 - 0.00086 19.1 0.7 0.051 13.4 0.3 2.5 1 1 1 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain DUF3584 PF12128.8 KXZ44367.1 - 0.00091 16.9 1.1 0.00094 16.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Gp58 PF07902.11 KXZ44367.1 - 0.00094 17.6 4.0 0.0016 16.9 4.0 1.3 1 0 0 1 1 1 1 gp58-like protein Jnk-SapK_ap_N PF09744.9 KXZ44367.1 - 0.001 19.3 7.5 0.21 11.8 7.5 2.7 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 BRE1 PF08647.11 KXZ44367.1 - 0.001 19.1 2.6 0.0013 18.7 0.8 2.0 2 1 0 2 2 1 1 BRE1 E3 ubiquitin ligase LXG PF04740.12 KXZ44367.1 - 0.001 18.8 3.7 0.088 12.5 1.7 2.3 1 1 1 2 2 2 2 LXG domain of WXG superfamily DUF4763 PF15960.5 KXZ44367.1 - 0.0011 18.4 3.3 0.34 10.2 2.9 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4763) H-kinase_dim PF02895.14 KXZ44367.1 - 0.0012 19.2 2.9 0.27 11.6 2.3 3.3 1 1 1 2 2 1 1 Signal transducing histidine kinase, homodimeric domain Leu_zip PF15294.6 KXZ44367.1 - 0.0012 18.5 3.7 0.0028 17.2 3.7 1.6 1 1 0 1 1 1 1 Leucine zipper HAUS-augmin3 PF14932.6 KXZ44367.1 - 0.0012 18.5 3.4 0.015 14.8 3.4 2.1 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 HemX PF04375.14 KXZ44367.1 - 0.0012 18.2 2.8 0.0031 16.9 2.7 1.7 1 1 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Snapin_Pallidin PF14712.6 KXZ44367.1 - 0.0012 19.2 3.5 0.028 14.8 1.4 2.7 1 1 1 2 2 2 2 Snapin/Pallidin Nsp1_C PF05064.13 KXZ44367.1 - 0.0013 18.5 3.9 0.048 13.5 0.8 2.4 1 1 1 2 2 2 2 Nsp1-like C-terminal region DUF4094 PF13334.6 KXZ44367.1 - 0.0015 18.9 7.1 4.8 7.7 5.6 4.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF1515 PF07439.11 KXZ44367.1 - 0.0016 18.5 1.0 0.49 10.4 0.1 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1515) Phage_GPO PF05929.11 KXZ44367.1 - 0.0017 18.0 0.8 0.0034 17.0 0.3 1.6 1 1 1 2 2 1 1 Phage capsid scaffolding protein (GPO) serine peptidase COG5 PF10392.9 KXZ44367.1 - 0.002 18.3 11.8 0.17 12.1 4.9 2.6 1 1 1 2 2 2 2 Golgi transport complex subunit 5 BST2 PF16716.5 KXZ44367.1 - 0.0021 18.6 2.7 0.27 11.9 0.3 2.8 2 1 1 3 3 2 1 Bone marrow stromal antigen 2 Syntaxin_2 PF14523.6 KXZ44367.1 - 0.0022 18.4 7.5 0.026 14.9 7.5 2.2 1 1 0 1 1 1 1 Syntaxin-like protein Flagellin_C PF00700.21 KXZ44367.1 - 0.0022 18.3 3.3 2.6 8.5 0.6 3.3 1 1 3 4 4 3 0 Bacterial flagellin C-terminal helical region AIP3 PF03915.13 KXZ44367.1 - 0.0023 17.1 3.4 0.0028 16.8 3.4 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Bacillus_HBL PF05791.11 KXZ44367.1 - 0.0024 17.7 0.6 0.32 10.8 0.2 2.2 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) CEP209_CC5 PF16574.5 KXZ44367.1 - 0.0024 18.0 0.8 4 7.6 0.0 2.8 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 APG6_N PF17675.1 KXZ44367.1 - 0.0026 18.3 1.1 0.0045 17.5 0.4 1.8 2 0 0 2 2 1 1 Apg6 coiled-coil region HBM PF16591.5 KXZ44367.1 - 0.0027 17.2 0.4 0.0055 16.2 0.4 1.5 1 0 0 1 1 1 1 Helical bimodular sensor domain ApoLp-III PF07464.11 KXZ44367.1 - 0.0029 17.7 3.8 0.012 15.8 2.9 2.3 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF4164 PF13747.6 KXZ44367.1 - 0.003 17.8 0.1 0.27 11.6 0.1 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4164) FH2 PF02181.23 KXZ44367.1 - 0.0032 16.6 3.9 0.0079 15.4 2.7 1.8 1 1 1 2 2 2 1 Formin Homology 2 Domain betaPIX_CC PF16523.5 KXZ44367.1 - 0.0034 17.2 0.3 1.5 8.7 0.1 2.5 1 1 1 2 2 2 0 betaPIX coiled coil Tnp_22_trimer PF17489.2 KXZ44367.1 - 0.0037 17.2 0.1 3.3 7.7 0.0 4.0 1 1 3 4 4 4 0 L1 transposable element trimerization domain UPF0242 PF06785.11 KXZ44367.1 - 0.0041 17.3 0.9 0.0068 16.5 0.6 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus LPP PF04728.13 KXZ44367.1 - 0.0041 17.5 14.5 0.83 10.1 0.1 4.4 1 1 4 5 5 5 1 Lipoprotein leucine-zipper Uso1_p115_C PF04871.13 KXZ44367.1 - 0.0041 17.5 2.2 0.03 14.7 2.2 2.3 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Ax_dynein_light PF10211.9 KXZ44367.1 - 0.0044 17.0 0.5 0.24 11.3 0.5 2.6 1 1 0 1 1 1 1 Axonemal dynein light chain Rab5-bind PF09311.11 KXZ44367.1 - 0.005 16.3 7.7 0.084 12.3 4.8 2.2 1 1 1 2 2 2 2 Rabaptin-like protein DegS PF05384.11 KXZ44367.1 - 0.0057 16.1 2.7 0.25 10.8 2.6 2.3 1 1 0 1 1 1 1 Sensor protein DegS DASH_Dam1 PF08653.10 KXZ44367.1 - 0.0062 16.3 10.4 3 7.7 0.3 4.4 1 1 2 3 3 3 0 DASH complex subunit Dam1 HMMR_N PF15905.5 KXZ44367.1 - 0.0062 16.1 2.2 0.01 15.3 2.2 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF4472 PF14739.6 KXZ44367.1 - 0.0062 17.2 5.4 0.76 10.5 3.0 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4472) YscO PF07321.12 KXZ44367.1 - 0.0069 16.3 0.8 0.7 9.8 0.2 2.8 1 1 1 2 2 2 1 Type III secretion protein YscO CENP-Q PF13094.6 KXZ44367.1 - 0.007 16.6 3.5 0.13 12.5 3.5 2.4 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit BORCS6 PF10157.9 KXZ44367.1 - 0.008 16.4 4.4 1.4 9.1 0.3 2.3 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 IFT57 PF10498.9 KXZ44367.1 - 0.0085 15.1 2.1 0.014 14.4 2.1 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 COG2 PF06148.11 KXZ44367.1 - 0.0088 16.1 9.0 0.34 11.0 2.6 3.4 2 1 1 3 3 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps5 PF09325.10 KXZ44367.1 - 0.0088 15.6 5.4 0.016 14.7 5.4 1.5 1 0 0 1 1 1 1 Vps5 C terminal like DUF4201 PF13870.6 KXZ44367.1 - 0.0096 15.7 0.4 0.29 10.8 0.4 2.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Not3 PF04065.15 KXZ44367.1 - 0.0099 15.3 4.0 0.034 13.6 4.0 1.8 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component BicD PF09730.9 KXZ44367.1 - 0.01 14.3 3.3 0.014 13.9 3.3 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D MCPsignal PF00015.21 KXZ44367.1 - 0.011 15.6 3.9 0.13 12.1 3.9 2.2 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Dynamitin PF04912.14 KXZ44367.1 - 0.011 15.1 7.2 0.06 12.7 6.5 2.1 1 1 0 1 1 1 0 Dynamitin Spc24 PF08286.11 KXZ44367.1 - 0.011 15.9 6.9 8.4 6.7 5.9 3.3 2 1 0 2 2 1 0 Spc24 subunit of Ndc80 GCR PF02155.15 KXZ44367.1 - 0.012 14.6 7.6 0.55 9.2 1.8 2.3 1 1 1 2 2 2 0 Glucocorticoid receptor CheZ PF04344.13 KXZ44367.1 - 0.013 15.4 0.4 0.023 14.6 0.4 1.4 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Blo-t-5 PF11642.8 KXZ44367.1 - 0.013 15.4 5.7 4.6 7.2 0.6 3.2 1 1 2 3 3 3 0 Mite allergen Blo t 5 PMEI PF04043.15 KXZ44367.1 - 0.014 15.8 0.3 1.1 9.6 0.1 2.3 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor HOOK PF05622.12 KXZ44367.1 - 0.014 13.6 1.1 0.019 13.1 1.1 1.1 1 0 0 1 1 1 0 HOOK protein bZIP_2 PF07716.15 KXZ44367.1 - 0.014 15.4 0.9 17 5.6 0.0 3.7 1 1 3 4 4 3 0 Basic region leucine zipper HAP1_N PF04849.13 KXZ44367.1 - 0.014 14.6 4.5 0.021 14.1 4.5 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HrpB7 PF09486.10 KXZ44367.1 - 0.016 15.6 0.0 2 8.8 0.0 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) PI3K_P85_iSH2 PF16454.5 KXZ44367.1 - 0.016 14.8 4.8 0.31 10.6 3.8 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAM76 PF16046.5 KXZ44367.1 - 0.017 14.5 2.1 0.025 14.0 2.1 1.3 1 0 0 1 1 1 0 FAM76 protein HsbA PF12296.8 KXZ44367.1 - 0.017 15.5 0.2 1.7 9.1 0.2 2.6 1 1 0 1 1 1 0 Hydrophobic surface binding protein A DUF641 PF04859.12 KXZ44367.1 - 0.017 15.4 2.0 1.1 9.6 0.8 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Cep57_CLD PF14073.6 KXZ44367.1 - 0.018 15.1 1.7 0.094 12.7 1.2 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF3251 PF11622.8 KXZ44367.1 - 0.019 14.6 1.7 1.6 8.4 0.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3251) TBK1_CCD1 PF18394.1 KXZ44367.1 - 0.019 14.5 4.5 1.7 8.1 3.6 2.5 1 1 1 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 SF-assemblin PF06705.11 KXZ44367.1 - 0.02 14.2 5.4 0.62 9.4 4.6 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin Mod_r PF07200.13 KXZ44367.1 - 0.02 15.0 1.9 0.04 14.0 1.9 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Seryl_tRNA_N PF02403.22 KXZ44367.1 - 0.021 15.1 0.1 0.73 10.1 0.1 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tweety PF04906.13 KXZ44367.1 - 0.024 13.3 4.7 0.047 12.4 4.6 1.5 1 1 0 1 1 1 0 Tweety Noelin-1 PF12308.8 KXZ44367.1 - 0.025 14.6 5.3 0.51 10.3 1.4 2.6 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF4695 PF15766.5 KXZ44367.1 - 0.025 14.8 4.1 26 5.1 4.1 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4695) Laminin_I PF06008.14 KXZ44367.1 - 0.028 14.1 3.3 0.064 13.0 3.3 1.6 1 1 0 1 1 1 0 Laminin Domain I STAT_alpha PF01017.20 KXZ44367.1 - 0.029 14.2 3.1 0.33 10.8 3.1 2.6 1 1 0 1 1 1 0 STAT protein, all-alpha domain FliJ PF02050.16 KXZ44367.1 - 0.03 14.6 0.2 0.19 12.0 0.2 2.2 1 1 0 1 1 1 0 Flagellar FliJ protein Spc29 PF17082.5 KXZ44367.1 - 0.031 14.1 6.4 0.66 9.8 6.1 2.3 1 1 0 1 1 1 0 Spindle Pole Component 29 FmiP_Thoc5 PF09766.9 KXZ44367.1 - 0.031 13.6 2.4 0.18 11.0 2.4 1.9 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 TSC22 PF01166.18 KXZ44367.1 - 0.031 14.6 4.7 12 6.3 1.5 3.8 1 1 1 2 2 2 0 TSC-22/dip/bun family Swi5 PF07061.11 KXZ44367.1 - 0.031 14.3 0.8 10 6.3 0.8 3.3 1 1 0 1 1 1 0 Swi5 Exonuc_VII_S PF02609.16 KXZ44367.1 - 0.032 14.3 0.0 14 5.8 0.0 3.0 1 1 0 2 2 2 0 Exonuclease VII small subunit DUF3552 PF12072.8 KXZ44367.1 - 0.033 13.6 0.6 0.068 12.6 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) GCN5L1 PF06320.13 KXZ44367.1 - 0.034 14.3 2.1 0.68 10.1 2.0 2.5 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Med4 PF10018.9 KXZ44367.1 - 0.04 13.6 3.1 0.62 9.7 3.1 2.6 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 5_nucleotid PF05761.14 KXZ44367.1 - 0.04 12.8 0.6 0.061 12.2 0.6 1.3 1 0 0 1 1 1 0 5' nucleotidase family WEMBL PF05701.11 KXZ44367.1 - 0.04 12.6 2.0 0.062 12.0 2.0 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CEP63 PF17045.5 KXZ44367.1 - 0.041 13.8 3.0 0.096 12.6 2.9 1.6 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa KLRAQ PF10205.9 KXZ44367.1 - 0.047 13.9 7.2 5.1 7.4 0.5 3.3 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein TPR_MLP1_2 PF07926.12 KXZ44367.1 - 0.049 13.7 2.6 1.7 8.7 2.1 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BRI3BP PF14965.6 KXZ44367.1 - 0.051 13.1 5.4 34 3.9 4.7 3.5 1 1 1 2 2 2 0 Negative regulator of p53/TP53 DUF677 PF05055.12 KXZ44367.1 - 0.052 12.4 2.4 0.11 11.4 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF677) IKBKB_SDD PF18397.1 KXZ44367.1 - 0.053 12.8 2.3 1.8 7.8 0.3 2.0 1 1 1 2 2 2 0 IQBAL scaffold dimerization domain Fmp27_WPPW PF10359.9 KXZ44367.1 - 0.053 12.4 5.7 0.16 10.8 5.7 1.8 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain JIP_LZII PF16471.5 KXZ44367.1 - 0.054 13.7 3.9 4.1 7.6 2.6 3.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Surfac_D-trimer PF09006.11 KXZ44367.1 - 0.058 13.3 0.1 22 5.0 0.0 3.8 1 1 3 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Spectrin PF00435.21 KXZ44367.1 - 0.063 13.8 2.2 1.1 9.8 2.3 2.5 1 1 0 1 1 1 0 Spectrin repeat Snf7 PF03357.21 KXZ44367.1 - 0.065 12.8 0.1 0.2 11.2 0.0 1.8 1 1 1 2 2 2 0 Snf7 Csm1_N PF18504.1 KXZ44367.1 - 0.066 13.6 6.1 5.1 7.5 2.3 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF2383 PF09537.10 KXZ44367.1 - 0.081 13.3 2.4 1 9.7 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) Cnn_1N PF07989.11 KXZ44367.1 - 0.083 13.1 2.0 2.4 8.4 0.8 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 MPS2 PF17060.5 KXZ44367.1 - 0.14 11.4 2.9 0.4 9.9 2.9 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 Phage_GP20 PF06810.11 KXZ44367.1 - 0.15 11.9 0.0 1 9.1 0.0 2.1 1 1 0 1 1 1 0 Phage minor structural protein GP20 Fusion_gly PF00523.18 KXZ44367.1 - 0.15 10.3 1.5 1.4 7.1 0.1 2.0 1 1 1 2 2 2 0 Fusion glycoprotein F0 Vac_Fusion PF02346.16 KXZ44367.1 - 0.17 11.5 2.8 2.1 8.0 0.5 3.1 1 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 USP8_interact PF08941.10 KXZ44367.1 - 0.17 11.6 3.5 1.6 8.5 0.6 2.3 1 1 1 2 2 2 0 USP8 interacting CCDC144C PF14915.6 KXZ44367.1 - 0.17 10.9 6.5 0.39 9.8 6.1 1.6 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF1465 PF07323.12 KXZ44367.1 - 0.18 11.6 3.3 7.1 6.4 3.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) DUF489 PF04356.12 KXZ44367.1 - 0.18 11.8 2.2 0.53 10.3 2.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF489) AI-2E_transport PF01594.16 KXZ44367.1 - 0.21 10.7 1.5 3 6.9 0.3 2.0 1 1 1 2 2 2 0 AI-2E family transporter V_ATPase_I PF01496.19 KXZ44367.1 - 0.21 9.5 4.2 0.52 8.2 4.1 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4600 PF15372.6 KXZ44367.1 - 0.24 11.8 3.8 1.6 9.2 1.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) MbeD_MobD PF04899.12 KXZ44367.1 - 0.3 11.2 4.0 15 5.8 0.7 3.1 1 1 1 2 2 2 0 MbeD/MobD like Tup_N PF08581.10 KXZ44367.1 - 0.38 11.1 2.4 5.5 7.4 2.1 2.5 1 1 2 3 3 2 0 Tup N-terminal LegC3_N PF18654.1 KXZ44367.1 - 0.42 9.8 9.6 3.5 6.8 1.8 2.2 1 1 1 2 2 2 0 LegC3 N-terminal coiled-coil domain DHR10 PF18595.1 KXZ44367.1 - 0.44 10.6 6.6 7.4 6.7 0.2 3.2 2 1 0 3 3 3 0 Designed helical repeat protein 10 domain PDCD7 PF16021.5 KXZ44367.1 - 0.51 9.4 5.4 3.8 6.5 5.4 2.3 1 1 0 1 1 1 0 Programmed cell death protein 7 Dzip-like_N PF13815.6 KXZ44367.1 - 0.51 10.3 3.2 16 5.5 0.6 2.9 1 1 3 4 4 3 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal BLOC1S3 PF15753.5 KXZ44367.1 - 0.6 10.2 11.7 0.59 10.2 0.9 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 UPF0449 PF15136.6 KXZ44367.1 - 0.82 10.2 2.7 27 5.3 0.3 3.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Cortex-I_coil PF09304.10 KXZ44367.1 - 0.9 9.8 4.2 4.8 7.4 4.2 2.1 1 1 0 1 1 1 0 Cortexillin I, coiled coil Wtap PF17098.5 KXZ44367.1 - 1.1 9.2 6.5 4.1 7.3 4.3 2.3 1 1 1 2 2 2 0 WTAP/Mum2p family TRPM_tetra PF16519.5 KXZ44367.1 - 1.2 9.3 5.9 12 6.0 1.2 2.9 1 1 2 3 3 3 0 Tetramerisation domain of TRPM Phage_tail_NK PF16532.5 KXZ44367.1 - 1.3 8.7 4.7 9.3 5.8 2.6 2.2 1 1 1 2 2 2 0 Sf6-type phage tail needle knob or tip of some Caudovirales DASH_Dad4 PF08650.10 KXZ44367.1 - 1.4 9.0 8.8 30 4.7 2.8 3.4 1 1 2 3 3 3 0 DASH complex subunit Dad4 PRKG1_interact PF15898.5 KXZ44367.1 - 1.5 9.7 6.3 1.5 9.8 2.6 2.7 1 1 2 3 3 2 0 cGMP-dependent protein kinase interacting domain DUF4061 PF13270.6 KXZ44367.1 - 2.6 8.4 6.8 24 5.3 5.6 2.7 1 1 1 2 2 1 0 Domain of unknown function (DUF4061) Sec34 PF04136.15 KXZ44367.1 - 2.8 7.8 7.3 38 4.1 7.3 2.3 1 1 0 1 1 1 0 Sec34-like family tRNA_U5-meth_tr PF05958.11 KXZ44369.1 - 3.4e-17 62.5 0.1 5e-16 58.6 0.1 2.0 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase AflR PF08493.10 KXZ44369.1 - 7.1 6.0 9.3 0.12 11.8 0.3 2.0 1 1 0 2 2 2 0 Aflatoxin regulatory protein tRNA_U5-meth_tr PF05958.11 KXZ44370.1 - 5.3e-37 127.6 0.0 5.9e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TPT PF03151.16 KXZ44371.1 - 5.1e-30 104.8 17.0 6.4e-30 104.5 17.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXZ44371.1 - 5.9e-08 32.3 20.3 8.2e-08 31.8 20.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXZ44371.1 - 0.11 12.6 34.8 0.18 12.0 11.7 2.4 2 0 0 2 2 2 0 EamA-like transporter family TPT PF03151.16 KXZ44372.1 - 1e-31 110.4 17.3 1.3e-31 110.1 17.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXZ44372.1 - 3e-10 39.8 18.2 4.3e-10 39.3 18.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXZ44372.1 - 0.6 10.3 28.6 0.085 13.0 8.0 2.3 2 0 0 2 2 2 0 EamA-like transporter family DUF2681 PF10883.8 KXZ44372.1 - 1.5 9.3 7.1 0.11 12.9 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Guanylate_cyc PF00211.20 KXZ44373.1 - 1.9e-42 144.9 0.0 3.2e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KXZ44373.1 - 2.1e-05 23.9 0.0 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ANF_receptor PF01094.28 KXZ44373.1 - 0.15 11.1 0.0 0.82 8.7 0.0 1.8 2 0 0 2 2 2 0 Receptor family ligand binding region S1 PF00575.23 KXZ44374.1 - 3.6e-79 261.1 2.2 1.4e-18 66.9 0.2 7.2 5 1 2 7 7 7 7 S1 RNA binding domain PCB_OB PF17092.5 KXZ44374.1 - 2.6e-09 37.8 0.0 0.55 11.0 0.0 6.6 4 3 1 6 6 6 2 Penicillin-binding protein OB-like domain CSD PF00313.22 KXZ44374.1 - 0.063 13.1 0.0 16 5.4 0.0 3.3 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain TRAM PF01938.20 KXZ44374.1 - 0.088 12.8 0.4 36 4.4 0.0 3.5 4 0 0 4 4 4 0 TRAM domain DUF4350 PF14258.6 KXZ44374.1 - 0.15 12.5 2.1 40 4.7 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4350) S1 PF00575.23 KXZ44375.1 - 1.8e-39 133.9 0.3 5.2e-13 49.1 0.0 4.2 4 0 0 4 4 4 4 S1 RNA binding domain DUF4131 PF13567.6 KXZ44375.1 - 1.9e-05 24.4 1.9 0.12 12.0 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) PCB_OB PF17092.5 KXZ44375.1 - 0.0002 22.1 0.6 0.88 10.3 0.0 4.0 1 1 1 4 4 4 2 Penicillin-binding protein OB-like domain EXOSC1 PF10447.9 KXZ44375.1 - 0.00077 20.1 0.4 5 7.8 0.0 3.7 3 1 0 3 3 3 1 Exosome component EXOSC1/CSL4 PrcB_C PF14343.6 KXZ44375.1 - 0.015 15.4 1.9 16 5.7 0.0 3.9 4 0 0 4 4 4 0 PrcB C-terminal TRAM PF01938.20 KXZ44375.1 - 0.047 13.7 0.5 6.8 6.8 0.0 3.6 4 0 0 4 4 4 0 TRAM domain OB_RNB PF08206.11 KXZ44375.1 - 0.27 11.0 1.8 7.9 6.2 0.0 3.5 4 0 0 4 4 4 0 Ribonuclease B OB domain S1 PF00575.23 KXZ44376.1 - 2.4e-44 149.5 1.3 6.7e-20 71.2 0.5 3.2 3 0 0 3 3 3 3 S1 RNA binding domain PCB_OB PF17092.5 KXZ44376.1 - 4.1e-06 27.5 0.1 0.41 11.4 0.1 4.2 1 1 4 5 5 5 2 Penicillin-binding protein OB-like domain eIF-1a PF01176.19 KXZ44376.1 - 0.1 12.4 0.3 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 S1_2 PF13509.6 KXZ44376.1 - 0.11 12.5 0.2 1.8 8.7 0.0 3.2 3 2 0 3 3 3 0 S1 domain S1 PF00575.23 KXZ44377.1 - 1.1e-51 173.0 0.0 4.3e-12 46.2 0.0 7.3 5 2 2 7 7 7 7 S1 RNA binding domain FLgD_tudor PF13861.6 KXZ44377.1 - 0.00087 19.5 0.0 9.5 6.5 0.0 4.8 4 2 0 4 4 4 1 FlgD Tudor-like domain PCB_OB PF17092.5 KXZ44377.1 - 0.0017 19.1 4.5 2 9.2 0.1 5.2 4 2 1 5 5 5 2 Penicillin-binding protein OB-like domain Bep_C_terminal PF17841.1 KXZ44377.1 - 0.05 13.8 0.1 1.1e+02 3.2 0.1 4.2 5 0 0 5 5 5 0 BID domain of Bartonella effector protein (Bep) PrcB_C PF14343.6 KXZ44377.1 - 0.18 11.9 0.0 1.2e+02 2.9 0.0 3.9 4 0 0 4 4 4 0 PrcB C-terminal zf-MYND PF01753.18 KXZ44378.1 - 7.3e-06 26.0 9.1 1.7e-05 24.8 9.1 1.6 1 0 0 1 1 1 1 MYND finger Ribosomal_S27e PF01667.17 KXZ44379.1 - 0.25 11.1 1.0 0.41 10.4 0.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S27 zf-RING_2 PF13639.6 KXZ44381.1 - 4.8e-09 36.4 7.5 6.9e-09 35.9 7.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXZ44381.1 - 5.4e-09 35.8 6.2 8.5e-09 35.2 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ44381.1 - 1.6e-08 34.2 4.0 2.2e-08 33.8 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ44381.1 - 4.8e-08 32.7 7.7 7.3e-08 32.1 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ44381.1 - 6.6e-05 22.9 2.2 0.00017 21.5 2.4 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ44381.1 - 6.6e-05 22.8 5.1 0.00011 22.1 5.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXZ44381.1 - 0.0001 22.1 4.3 0.00017 21.4 4.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXZ44381.1 - 0.0002 21.6 8.6 0.00046 20.4 8.6 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KXZ44381.1 - 0.019 14.7 5.5 0.038 13.8 5.5 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 KXZ44381.1 - 0.021 14.9 3.6 0.042 13.9 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 KXZ44381.1 - 0.069 13.3 8.9 0.34 11.1 8.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KXZ44381.1 - 0.15 11.8 2.5 0.32 10.8 2.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger Totivirus_coat PF05518.11 KXZ44381.1 - 0.16 10.0 3.3 0.19 9.8 3.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein zinc-ribbons_6 PF07191.12 KXZ44381.1 - 0.19 11.8 4.1 0.66 10.0 4.1 1.8 1 1 0 1 1 1 0 zinc-ribbons DZR PF12773.7 KXZ44381.1 - 0.95 9.5 5.9 8.6 6.5 5.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon F-box-like PF12937.7 KXZ44382.1 - 1.8e-08 34.1 1.4 3e-08 33.4 1.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ44382.1 - 2.5e-05 24.0 0.2 3.6e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXZ44382.1 - 0.06 13.2 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 F-box Lyase_1 PF00206.20 KXZ44383.1 - 8.8e-105 350.5 0.0 1.1e-104 350.2 0.0 1.0 1 0 0 1 1 1 1 Lyase CENP-B_N PF04218.13 KXZ44384.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_11 PF08279.12 KXZ44384.1 - 0.24 11.4 0.2 0.39 10.7 0.2 1.3 1 0 0 1 1 1 0 HTH domain CWC25 PF12542.8 KXZ44386.1 - 1.2e-15 58.3 3.8 1.2e-15 58.3 3.8 4.2 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KXZ44386.1 - 5.1e-10 39.4 13.5 5.1e-10 39.4 13.5 9.7 10 0 0 10 10 10 1 N-terminal domain of CBF1 interacting co-repressor CIR TPR_2 PF07719.17 KXZ44387.1 - 1.2e-11 43.8 8.0 3.7e-05 23.5 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ44387.1 - 7.3e-11 41.4 5.9 2.4e-05 23.9 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ44387.1 - 9.8e-10 38.6 23.1 2.4e-06 27.8 5.5 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ44387.1 - 1.8e-08 34.9 10.5 4.2e-07 30.5 5.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_21 PF09976.9 KXZ44387.1 - 2e-06 27.7 3.8 3e-06 27.1 3.8 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 KXZ44387.1 - 8.5e-05 22.5 3.6 0.26 11.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ44387.1 - 0.00029 20.3 3.1 0.00038 19.9 3.1 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_11 PF13414.6 KXZ44387.1 - 0.00034 20.2 7.6 0.03 14.0 1.3 3.4 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.6 KXZ44387.1 - 0.00037 20.6 7.0 0.00088 19.4 3.6 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ44387.1 - 0.00093 19.8 9.7 0.11 13.4 1.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ44387.1 - 0.0012 19.3 7.7 0.0069 16.9 3.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.20 KXZ44387.1 - 0.0015 18.4 0.2 0.0018 18.2 0.2 1.1 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_10 PF13374.6 KXZ44387.1 - 0.0022 17.8 10.8 0.36 10.8 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ44387.1 - 0.0028 17.9 4.5 0.009 16.2 4.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXZ44387.1 - 0.0051 17.1 1.1 0.037 14.4 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ44387.1 - 0.026 14.6 4.5 0.16 12.0 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat HBM PF16591.5 KXZ44387.1 - 0.038 13.4 0.8 0.055 12.9 0.5 1.4 1 1 0 1 1 1 0 Helical bimodular sensor domain DNA_processg_A PF02481.15 KXZ44387.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 2 0 0 2 2 2 0 DNA recombination-mediator protein A TPR_6 PF13174.6 KXZ44387.1 - 0.083 13.6 7.1 1.2 9.9 1.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ44388.1 - 7.7e-32 106.8 3.4 0.00011 22.1 0.0 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ44388.1 - 5.2e-30 102.0 0.0 5.4e-05 22.8 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ44388.1 - 2.1e-25 86.7 0.0 0.0003 20.8 0.0 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ44388.1 - 5.4e-17 61.8 9.7 5.9e-06 26.5 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ44388.1 - 1e-16 61.2 10.5 9.4e-06 26.0 0.0 5.9 2 1 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ44388.1 - 2.7e-16 59.9 42.4 1.7e-06 28.5 0.0 7.7 6 2 2 8 8 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ44388.1 - 4.4e-16 58.0 0.0 0.00021 21.5 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ44388.1 - 7.3e-15 54.4 0.9 0.018 14.7 0.0 6.7 3 2 3 6 6 6 5 TPR repeat TPR_9 PF13371.6 KXZ44388.1 - 6.1e-13 48.7 25.2 0.001 19.2 0.7 6.9 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ44388.1 - 9.9e-13 47.2 4.0 0.0052 16.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ44388.1 - 2.4e-11 43.5 4.8 3 8.7 0.0 8.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ44388.1 - 1.6e-10 40.9 39.4 0.025 15.4 0.1 10.5 7 2 5 12 12 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ44388.1 - 2.8e-07 30.7 0.3 0.022 15.0 0.0 3.0 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXZ44388.1 - 1.8e-05 24.4 19.8 0.13 12.2 0.2 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ44388.1 - 1.8e-05 24.1 7.1 0.54 9.4 0.6 4.7 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ44388.1 - 0.0035 16.8 8.8 0.035 13.5 4.2 3.9 2 1 0 3 3 3 1 MalT-like TPR region BTAD PF03704.17 KXZ44388.1 - 0.005 17.3 11.9 1.1 9.7 3.2 4.6 2 1 0 3 3 3 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KXZ44388.1 - 0.012 14.5 0.1 7.1 5.4 0.0 3.2 2 2 1 3 3 3 0 NMDA receptor-regulated protein 1 FAT PF02259.23 KXZ44388.1 - 0.02 14.1 0.1 2.4 7.3 0.1 2.4 1 1 1 2 2 2 0 FAT domain Fis1_TPR_C PF14853.6 KXZ44388.1 - 0.044 13.8 0.6 0.21 11.7 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_5 PF12688.7 KXZ44388.1 - 0.25 11.6 6.4 7.2 6.9 0.2 3.3 3 1 1 4 4 3 0 Tetratrico peptide repeat DUF5481 PF17578.2 KXZ44389.1 - 0.073 13.5 3.5 0.12 12.7 0.8 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5481) Choline_transpo PF04515.12 KXZ44390.1 - 4e-95 318.8 32.2 4e-95 318.8 32.2 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter SAT PF16073.5 KXZ44390.1 - 0.35 10.6 1.6 79 2.9 0.0 3.4 3 0 0 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DLH PF01738.18 KXZ44391.1 - 1e-30 106.9 0.0 1.3e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXZ44391.1 - 0.00012 21.4 0.0 0.14 11.4 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXZ44391.1 - 0.011 15.2 0.0 2 7.8 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXZ44391.1 - 0.013 15.1 0.1 0.039 13.6 0.1 1.8 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ44391.1 - 0.037 14.6 0.1 0.047 14.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.11 KXZ44391.1 - 0.11 12.3 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KXZ44391.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 KXZ44392.1 - 3.6e-27 95.3 0.0 5e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXZ44392.1 - 0.0013 18.1 0.0 1.2 8.4 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXZ44392.1 - 0.0021 17.6 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXZ44392.1 - 0.0035 18.0 0.5 0.0046 17.6 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KXZ44392.1 - 0.0048 16.8 0.1 0.021 14.8 0.1 1.8 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KXZ44392.1 - 0.017 15.0 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KXZ44392.1 - 0.071 12.8 0.1 0.26 10.9 0.1 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold HCNGP PF07818.13 KXZ44393.1 - 2.8e-25 88.8 0.1 4.5e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 HCNGP-like protein HCNGP PF07818.13 KXZ44394.1 - 6e-08 33.2 0.0 6.5e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 HCNGP-like protein DEAD PF00270.29 KXZ44396.1 - 3.4e-49 167.0 0.0 2.9e-48 163.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ44396.1 - 3.2e-32 111.2 0.0 1.2e-31 109.3 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ44396.1 - 1.1e-05 25.5 0.0 2.9e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXZ44396.1 - 2.8e-05 23.5 0.0 4.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DNA_pol_lambd_f PF10391.9 KXZ44397.1 - 4.9e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KXZ44397.1 - 0.00021 21.6 0.0 0.12 12.7 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix domain HHH_5 PF14520.6 KXZ44397.1 - 0.012 16.2 0.0 0.28 11.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain FliG_M PF14841.6 KXZ44397.1 - 0.019 15.2 0.1 0.042 14.1 0.1 1.5 1 0 0 1 1 1 0 FliG middle domain DNA_pol_B_thumb PF14791.6 KXZ44399.1 - 4.6e-12 45.9 0.0 1.1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase beta thumb TLC PF03219.14 KXZ44400.1 - 5.4e-103 345.3 3.8 6e-103 345.2 3.8 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF4231 PF14015.6 KXZ44400.1 - 3 8.4 4.9 9 6.8 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) TLC PF03219.14 KXZ44401.1 - 1.7e-42 145.8 0.4 2e-42 145.6 0.4 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter SSURE PF11966.8 KXZ44401.1 - 0.0094 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding repeat Ion_trans PF00520.31 KXZ44402.1 - 9.8e-37 126.5 15.5 1.2e-36 126.2 15.5 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXZ44402.1 - 1.4e-09 37.8 7.5 1.4e-09 37.8 7.5 2.1 2 0 0 2 2 2 1 Ion channel OrfB_IS605 PF01385.19 KXZ44402.1 - 0.016 15.5 0.1 0.075 13.3 0.1 2.1 2 0 0 2 2 2 0 Probable transposase PKD_channel PF08016.12 KXZ44402.1 - 3.2 6.3 10.9 5.4 5.6 10.9 1.3 1 1 0 1 1 1 0 Polycystin cation channel zf-MYND PF01753.18 KXZ44403.1 - 6.2e-05 23.0 5.0 0.00011 22.2 5.0 1.4 1 0 0 1 1 1 1 MYND finger AAA PF00004.29 KXZ44405.1 - 3.4e-38 131.1 0.0 7.1e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ44405.1 - 4.3e-08 32.8 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXZ44405.1 - 3.6e-05 23.6 0.0 8e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXZ44405.1 - 0.00014 21.9 0.1 0.00086 19.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXZ44405.1 - 0.00074 18.8 0.1 0.0016 17.7 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KXZ44405.1 - 0.00087 19.7 0.7 0.0065 16.9 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KXZ44405.1 - 0.0019 18.3 0.0 0.0054 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 KXZ44405.1 - 0.0027 17.7 0.3 0.014 15.4 0.0 2.4 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KXZ44405.1 - 0.033 14.5 5.8 0.046 14.0 0.4 2.7 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXZ44405.1 - 0.033 13.6 0.1 0.089 12.2 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXZ44405.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KXZ44405.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KXZ44405.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXZ44405.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ44405.1 - 0.16 12.5 0.0 0.7 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DHC_N2 PF08393.13 KXZ44406.1 - 1.2e-07 31.2 0.0 0.0038 16.4 0.0 2.5 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 2 Kelch_6 PF13964.6 KXZ44407.1 - 2.3e-13 49.9 4.9 0.00013 22.1 0.2 5.1 3 2 2 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KXZ44407.1 - 6.2e-11 42.0 19.1 0.0013 18.7 0.0 6.9 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KXZ44407.1 - 1.8e-09 37.0 9.5 8.6e-07 28.5 0.5 4.6 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KXZ44407.1 - 1.4e-08 34.6 15.3 0.062 13.3 0.0 5.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KXZ44407.1 - 1.1e-06 28.4 17.9 0.0085 16.0 0.2 6.2 5 1 1 6 6 6 2 Kelch motif Kelch_3 PF13415.6 KXZ44407.1 - 2.7e-05 24.3 24.1 0.0027 18.0 0.2 7.4 8 0 0 8 8 8 2 Galactose oxidase, central domain SDA1 PF05285.12 KXZ44407.1 - 1.7 8.0 17.5 2.3 7.6 17.5 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KXZ44407.1 - 8.1 5.7 13.4 15 4.8 13.4 1.3 1 0 0 1 1 1 0 NOA36 protein ATPase_2 PF01637.18 KXZ44408.1 - 1.6e-08 34.7 0.0 0.00023 21.1 0.0 2.1 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KXZ44408.1 - 3.5e-07 30.7 2.7 4.3e-07 30.5 0.9 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXZ44408.1 - 1.7e-05 24.8 0.0 0.0021 18.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXZ44408.1 - 2.7e-05 24.5 0.0 0.0013 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ44408.1 - 0.0057 16.4 0.0 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXZ44408.1 - 0.0098 16.1 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ44408.1 - 0.022 15.1 0.1 0.048 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ44408.1 - 0.026 15.0 0.0 4.1 7.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 KXZ44408.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSM_b PF10741.9 KXZ44408.1 - 0.18 11.6 1.4 5.1 6.9 1.4 2.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b AAA_18 PF13238.6 KXZ44408.1 - 0.19 12.3 0.0 0.44 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2076 PF09849.9 KXZ44408.1 - 2.2 8.2 7.2 1.1 9.2 2.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) PseudoU_synth_1 PF01416.20 KXZ44411.1 - 2.8e-11 43.8 0.0 0.00018 21.9 0.0 2.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase Helicase_C PF00271.31 KXZ44412.1 - 7.6e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ44412.1 - 1.5e-08 34.6 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ44412.1 - 0.025 14.6 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KXZ44412.1 - 0.17 12.3 1.4 0.47 10.8 1.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M11 PF05548.11 KXZ44413.1 - 2.8e-36 125.3 0.0 4.9e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Gametolysin peptidase M11 F5_F8_type_C PF00754.25 KXZ44413.1 - 0.00011 22.3 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF5000 PF16391.5 KXZ44413.1 - 0.15 12.1 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function Ank_4 PF13637.6 KXZ44414.1 - 1.6e-07 31.7 7.4 0.0029 18.1 0.1 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44414.1 - 2.7e-07 31.1 3.7 0.0036 17.9 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ44414.1 - 0.045 14.1 6.4 29 5.1 0.0 4.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44414.1 - 0.25 12.0 9.3 33 5.5 0.1 6.3 8 0 0 8 8 8 0 Ankyrin repeat SET PF00856.28 KXZ44416.1 - 0.00051 20.5 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF913 PF06025.12 KXZ44418.1 - 7.7e-52 176.5 0.0 4e-51 174.1 0.0 2.2 1 1 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KXZ44418.1 - 1.1e-11 44.8 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) UBA PF00627.31 KXZ44418.1 - 3.8e-06 26.7 0.1 9.9e-06 25.4 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Arm PF00514.23 KXZ44418.1 - 1 9.5 5.8 22 5.3 0.2 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ACT PF01842.25 KXZ44419.1 - 3.4e-14 52.3 0.0 6.3e-06 25.9 0.0 3.4 3 0 0 3 3 3 3 ACT domain ACT_4 PF13291.6 KXZ44419.1 - 8.7e-06 26.2 0.0 0.42 11.2 0.0 3.4 3 1 0 3 3 3 2 ACT domain ACT_6 PF13740.6 KXZ44419.1 - 0.00068 19.6 0.2 0.66 10.0 0.0 2.7 2 0 0 2 2 2 2 ACT domain Pkinase_Tyr PF07714.17 KXZ44420.1 - 2.6e-23 82.6 0.0 1.7e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ44420.1 - 6.6e-20 71.6 0.0 2.7e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain GHMP_kinases_C PF08544.13 KXZ44420.1 - 0.047 14.1 1.9 1.6 9.2 1.1 3.3 2 0 0 2 2 2 0 GHMP kinases C terminal PGM_PMM_I PF02878.16 KXZ44421.1 - 1.1e-38 132.0 0.0 2.1e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXZ44421.1 - 2.8e-13 50.1 0.1 1.9e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXZ44421.1 - 3.1e-13 50.2 0.0 2e-12 47.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Ank_2 PF12796.7 KXZ44421.1 - 5.8e-10 39.6 0.4 0.00055 20.5 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44421.1 - 9.3e-08 32.5 4.9 0.048 14.3 0.2 5.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44421.1 - 1.6e-05 25.0 0.7 4.2 7.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44421.1 - 0.00079 19.7 0.7 44 5.1 0.1 6.8 9 0 0 9 9 9 0 Ankyrin repeat Ank PF00023.30 KXZ44421.1 - 3.7 8.1 4.9 30 5.3 0.1 3.8 4 0 0 4 4 4 0 Ankyrin repeat Ion_trans PF00520.31 KXZ44423.1 - 5.4e-14 52.0 3.8 8.1e-14 51.4 3.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KXZ44423.1 - 8.6e-14 51.9 0.8 6.7e-12 45.8 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44423.1 - 1.6e-10 41.3 0.5 8.8e-06 26.2 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44423.1 - 6.8e-10 38.3 0.1 0.0034 17.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXZ44423.1 - 8.6e-09 35.5 0.5 0.00037 20.8 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXZ44423.1 - 4.6e-08 33.2 0.5 1.5e-06 28.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) cNMP_binding PF00027.29 KXZ44423.1 - 0.00019 21.4 0.5 0.2 11.7 0.0 3.0 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain WD40 PF00400.32 KXZ44424.1 - 6.7e-13 48.9 0.6 0.0017 19.1 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44424.1 - 2.7e-06 27.6 0.0 0.57 10.5 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ44424.1 - 0.013 14.4 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tim54 PF11711.8 KXZ44425.1 - 0.00055 18.8 6.9 0.00063 18.6 6.9 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.9 KXZ44425.1 - 0.001 19.3 11.1 0.001 19.2 11.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 KXZ44425.1 - 0.011 14.0 13.2 0.011 14.0 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXZ44425.1 - 0.013 15.0 12.6 0.013 15.0 12.6 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KXZ44425.1 - 0.018 14.4 10.9 0.018 14.3 10.9 1.1 1 0 0 1 1 1 0 NOA36 protein Mpp10 PF04006.12 KXZ44425.1 - 0.022 13.2 15.5 0.025 13.0 15.5 1.0 1 0 0 1 1 1 0 Mpp10 protein Pox_Ag35 PF03286.14 KXZ44425.1 - 0.03 14.1 10.4 0.031 14.0 10.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rpp20 PF12328.8 KXZ44425.1 - 0.032 14.2 2.1 0.047 13.7 2.1 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P RPA43_OB PF17875.1 KXZ44425.1 - 0.035 14.7 7.1 0.051 14.2 7.1 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RR_TM4-6 PF06459.12 KXZ44425.1 - 0.042 13.7 9.6 0.048 13.5 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FYDLN_acid PF09538.10 KXZ44425.1 - 0.048 14.3 9.9 0.083 13.6 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 KXZ44425.1 - 0.056 13.1 10.7 0.088 12.5 10.7 1.4 1 0 0 1 1 1 0 FAM176 family AIF_C PF14721.6 KXZ44425.1 - 0.056 13.8 1.9 0.071 13.5 1.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Paf1 PF03985.13 KXZ44425.1 - 0.061 12.3 17.1 0.062 12.3 17.1 1.1 1 0 0 1 1 1 0 Paf1 CPSF100_C PF13299.6 KXZ44425.1 - 0.068 13.3 4.2 0.076 13.2 4.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BUD22 PF09073.10 KXZ44425.1 - 0.073 12.4 10.2 0.072 12.4 10.2 1.1 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 KXZ44425.1 - 0.094 11.9 10.0 0.11 11.7 10.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.10 KXZ44425.1 - 0.1 13.0 14.3 0.18 12.2 14.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Radial_spoke PF04712.12 KXZ44425.1 - 0.11 11.4 16.7 0.13 11.1 16.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Rad54_N PF08658.10 KXZ44425.1 - 0.12 12.5 5.4 0.19 11.9 5.4 1.3 1 0 0 1 1 1 0 Rad54 N terminal TFIIF_alpha PF05793.12 KXZ44425.1 - 0.13 10.9 15.9 0.13 10.9 15.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CobT PF06213.12 KXZ44425.1 - 0.18 11.2 16.4 0.23 10.8 16.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mlh1_C PF16413.5 KXZ44425.1 - 0.18 11.2 5.2 0.22 10.9 5.2 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus EIIBC-GUT_N PF03612.14 KXZ44425.1 - 0.2 11.4 4.2 0.25 11.1 4.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GNAT_acetyltr_2 PF13718.6 KXZ44425.1 - 0.21 11.0 3.5 0.25 10.7 3.5 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Drc1-Sld2 PF11719.8 KXZ44425.1 - 0.21 11.1 9.0 0.21 11.1 9.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein RXT2_N PF08595.11 KXZ44425.1 - 0.21 11.6 9.6 0.28 11.2 9.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Prothymosin PF03247.14 KXZ44425.1 - 0.24 11.9 30.1 0.4 11.1 30.1 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family PPP4R2 PF09184.11 KXZ44425.1 - 0.26 10.8 16.0 0.3 10.6 16.0 1.1 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 KXZ44425.1 - 0.34 9.6 5.0 0.37 9.5 5.0 1.1 1 0 0 1 1 1 0 Presenilin Usp PF00582.26 KXZ44425.1 - 0.37 11.3 7.5 0.49 10.9 7.5 1.3 1 0 0 1 1 1 0 Universal stress protein family MDM31_MDM32 PF08118.11 KXZ44425.1 - 0.38 9.4 3.5 0.44 9.2 3.5 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins FAM60A PF15396.6 KXZ44425.1 - 0.39 10.7 2.2 0.42 10.6 2.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A THOC2_N PF16134.5 KXZ44425.1 - 0.49 9.0 3.9 0.47 9.0 3.9 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Connexin PF00029.19 KXZ44425.1 - 0.52 10.0 7.0 0.63 9.7 7.0 1.1 1 0 0 1 1 1 0 Connexin RPN2_C PF18004.1 KXZ44425.1 - 0.58 10.1 12.5 0.73 9.7 12.5 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PI3K_1B_p101 PF10486.9 KXZ44425.1 - 0.68 7.6 9.0 0.75 7.5 9.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit V_ATPase_I PF01496.19 KXZ44425.1 - 0.69 7.8 8.2 0.68 7.8 8.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Folate_carrier PF01770.18 KXZ44425.1 - 0.69 8.6 2.8 0.79 8.4 2.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier RNA_polI_A34 PF08208.11 KXZ44425.1 - 0.75 9.8 10.6 0.79 9.8 10.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 KXZ44425.1 - 0.75 8.0 14.0 0.85 7.8 14.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 KXZ44425.1 - 0.9 8.9 8.3 1.1 8.6 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CLN3 PF02487.17 KXZ44425.1 - 1 8.3 2.6 1.1 8.2 2.6 1.0 1 0 0 1 1 1 0 CLN3 protein DNA_pol_phi PF04931.13 KXZ44425.1 - 1.2 7.1 22.2 1.4 6.9 22.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF740 PF05340.12 KXZ44425.1 - 1.5 7.5 10.0 1.4 7.6 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Thg1C PF14413.6 KXZ44425.1 - 1.5 9.0 6.1 2 8.6 6.1 1.2 1 0 0 1 1 1 0 Thg1 C terminal domain CENP-T_N PF16171.5 KXZ44425.1 - 1.7 7.4 7.6 1.7 7.4 7.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus DUF913 PF06025.12 KXZ44425.1 - 1.9 7.4 6.1 1.9 7.4 6.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Astro_capsid_p PF12226.8 KXZ44425.1 - 2.3 7.3 15.9 2.6 7.1 15.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Spore_coat_CotO PF14153.6 KXZ44425.1 - 2.4 8.0 17.2 3.1 7.7 17.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nop53 PF07767.11 KXZ44425.1 - 2.5 7.4 19.5 3.2 7.1 19.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TLP-20 PF06088.11 KXZ44425.1 - 3 7.7 7.3 4 7.3 7.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) D123 PF07065.14 KXZ44425.1 - 3.7 6.6 7.9 4.8 6.3 7.9 1.2 1 0 0 1 1 1 0 D123 Sporozoite_P67 PF05642.11 KXZ44425.1 - 4.6 5.2 10.2 5.7 4.9 10.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2254 PF10011.9 KXZ44425.1 - 5.1 5.8 5.0 6.4 5.5 5.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) HSP90 PF00183.18 KXZ44425.1 - 5.6 5.7 18.5 6.8 5.5 18.5 1.0 1 0 0 1 1 1 0 Hsp90 protein EBV-NA3 PF05009.12 KXZ44425.1 - 5.6 6.4 6.7 6.3 6.2 6.7 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Sec62 PF03839.16 KXZ44425.1 - 5.9 6.3 5.6 7.3 6.0 5.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2457 PF10446.9 KXZ44425.1 - 6 5.9 21.2 7.7 5.5 21.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GREB1 PF15782.5 KXZ44425.1 - 6.9 3.6 8.1 8.1 3.4 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FHIPEP PF00771.20 KXZ44425.1 - 7.8 4.8 5.6 9.2 4.6 5.6 1.0 1 0 0 1 1 1 0 FHIPEP family Smg4_UPF3 PF03467.15 KXZ44425.1 - 8.9 6.3 11.6 12 5.9 11.6 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Merozoite_SPAM PF07133.11 KXZ44425.1 - 9.4 6.2 34.7 12 5.9 34.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF4637 PF15470.6 KXZ44425.1 - 9.4 5.9 20.9 15 5.3 20.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SPATA1_C PF15743.5 KXZ44428.1 - 0.037 14.1 1.9 0.037 14.1 1.9 1.8 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus IFP_35_N PF07334.13 KXZ44428.1 - 0.062 13.4 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus MCM3AP_GANP PF16769.5 KXZ44428.1 - 0.084 11.1 2.2 0.098 10.9 2.2 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP CortBP2 PF09727.9 KXZ44428.1 - 0.085 12.8 6.1 0.22 11.4 1.3 2.1 2 0 0 2 2 2 0 Cortactin-binding protein-2 UBA PF00627.31 KXZ44429.1 - 2e-12 46.8 0.8 7.5e-12 44.9 0.8 2.1 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 KXZ44429.1 - 3.1e-10 39.7 0.0 5.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KXZ44429.1 - 9.5e-10 38.3 32.1 1.8e-05 24.6 0.7 5.5 3 1 1 4 4 4 4 STI1 domain HOIP-UBA PF16678.5 KXZ44429.1 - 0.0039 17.2 0.1 0.0084 16.1 0.1 1.5 1 0 0 1 1 1 1 HOIP UBA domain pair CUE PF02845.16 KXZ44429.1 - 0.0049 16.5 0.4 0.042 13.6 0.0 2.5 2 0 0 2 2 2 1 CUE domain Rad60-SLD PF11976.8 KXZ44429.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LPD22 PF18834.1 KXZ44429.1 - 0.0075 16.4 1.9 1.7 8.9 0.4 2.6 2 0 0 2 2 2 2 Large polyvalent protein associated domain 22 XPC-binding PF09280.11 KXZ44429.1 - 0.009 15.7 19.3 0.044 13.5 2.2 4.8 2 2 2 4 4 4 2 XPC-binding domain BSD PF03909.17 KXZ44429.1 - 0.055 13.5 1.2 1 9.4 0.0 3.3 2 2 0 2 2 2 0 BSD domain RasGEF_N_2 PF14663.6 KXZ44429.1 - 0.15 12.5 0.1 0.94 9.9 0.0 2.2 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain UBA_4 PF14555.6 KXZ44429.1 - 0.37 10.6 3.7 1 9.2 0.1 3.1 4 0 0 4 4 4 0 UBA-like domain GlnE PF03710.15 KXZ44429.1 - 0.41 10.0 2.3 15 4.9 0.1 2.3 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase Spc7 PF08317.11 KXZ44430.1 - 0.00031 19.7 9.7 0.00031 19.7 9.7 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein HOOK PF05622.12 KXZ44430.1 - 0.0026 16.0 10.8 0.0034 15.6 10.8 1.1 1 0 0 1 1 1 1 HOOK protein DUF641 PF04859.12 KXZ44430.1 - 0.005 17.2 4.9 0.005 17.2 4.9 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) Fez1 PF06818.15 KXZ44430.1 - 0.0087 16.5 14.3 0.0087 16.5 14.3 2.0 1 1 1 2 2 2 1 Fez1 zf-C4H2 PF10146.9 KXZ44430.1 - 0.021 15.2 0.3 0.037 14.3 0.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein GAS PF13851.6 KXZ44430.1 - 0.05 12.9 14.5 0.13 11.6 11.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KXZ44430.1 - 0.079 12.5 17.7 0.24 10.9 7.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.7 KXZ44430.1 - 0.089 12.9 16.7 0.16 12.1 16.7 1.4 1 0 0 1 1 1 0 Tropomyosin like Sec5 PF15469.6 KXZ44430.1 - 0.16 11.8 0.6 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 FH2 PF02181.23 KXZ44430.1 - 0.41 9.7 2.3 0.62 9.1 2.3 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain AAA_13 PF13166.6 KXZ44430.1 - 1.7 7.2 5.1 3.1 6.3 5.1 1.3 1 0 0 1 1 1 0 AAA domain COG2 PF06148.11 KXZ44430.1 - 1.9 8.6 9.7 4.3 7.4 2.5 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2333 PF10095.9 KXZ44430.1 - 2.8 6.9 10.8 3.9 6.4 10.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) SHE3 PF17078.5 KXZ44430.1 - 4.6 6.9 6.3 6.8 6.3 6.3 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TMF_TATA_bd PF12325.8 KXZ44430.1 - 5.7 7.2 15.9 3.4 7.9 5.6 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding IFT57 PF10498.9 KXZ44430.1 - 6.4 5.6 8.2 1.2 8.0 3.2 1.8 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 Toluene_X PF03349.16 KXZ44431.1 - 0.022 13.3 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) C2 PF00168.30 KXZ44434.1 - 8.4e-15 54.9 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain SpoU_methylase PF00588.19 KXZ44435.1 - 1.1e-23 84.0 0.0 2.7e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family CDV3 PF15359.6 KXZ44437.1 - 2.2 8.8 11.0 0.065 13.7 1.9 2.4 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 Pkinase PF00069.25 KXZ44439.1 - 1.1e-27 97.1 0.0 7.3e-18 64.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44439.1 - 4.9e-26 91.6 0.0 6.5e-15 55.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ44439.1 - 0.034 14.1 0.0 0.034 14.1 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S13_N PF08069.12 KXZ44440.1 - 0.048 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain NMD3 PF04981.13 KXZ44442.1 - 2.5e-27 95.9 1.8 3.3e-27 95.5 1.8 1.1 1 0 0 1 1 1 1 NMD3 family LRR_6 PF13516.6 KXZ44444.1 - 1e-12 47.0 17.2 0.0045 16.9 0.0 8.7 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KXZ44444.1 - 2e-10 40.7 1.5 0.025 15.0 0.0 6.6 3 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ44444.1 - 0.00011 21.8 13.8 1.9 8.3 0.1 6.3 4 3 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 KXZ44444.1 - 0.043 14.4 16.4 8.2 7.4 0.1 8.2 9 1 0 9 9 9 0 Leucine Rich Repeat F-box PF00646.33 KXZ44444.1 - 0.13 12.2 0.0 29 4.7 0.0 3.3 2 0 0 2 2 2 0 F-box domain Hemerythrin PF01814.23 KXZ44445.1 - 3.9e-07 30.7 4.8 8e-06 26.5 3.8 2.4 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LETM1 PF07766.13 KXZ44449.1 - 2.3e-95 319.0 0.6 3.4e-95 318.4 0.6 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 KXZ44449.1 - 0.038 13.8 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 SAP domain POTRA_TamA_1 PF17243.2 KXZ44449.1 - 0.072 13.2 0.2 0.34 11.0 0.2 2.1 1 0 0 1 1 1 0 POTRA domain TamA domain 1 SR-25 PF10500.9 KXZ44449.1 - 0.25 10.9 1.0 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_M22 PF00814.25 KXZ44450.1 - 7.1e-77 258.8 4.0 2.4e-60 204.5 2.7 3.0 1 1 1 2 2 2 2 Glycoprotease family TsaE PF02367.17 KXZ44450.1 - 1.6e-18 66.9 0.0 2e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE HIT PF01230.23 KXZ44450.1 - 1.5e-17 64.1 0.0 6.7e-17 62.0 0.0 2.1 2 0 0 2 2 2 1 HIT domain AAA_16 PF13191.6 KXZ44450.1 - 0.021 15.2 0.1 0.021 15.2 0.1 3.6 4 0 0 4 4 4 0 AAA ATPase domain Zeta_toxin PF06414.12 KXZ44450.1 - 0.062 12.6 1.1 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DcpS_C PF11969.8 KXZ44450.1 - 0.066 13.7 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding ABC_tran PF00005.27 KXZ44450.1 - 0.078 13.5 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter OAS1_C PF10421.9 KXZ44451.1 - 0.11 12.0 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus OAS1_C PF10421.9 KXZ44452.1 - 0.0066 16.0 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 2 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Usp PF00582.26 KXZ44455.1 - 0.00034 21.1 1.1 0.01 16.3 1.1 2.2 1 1 0 1 1 1 1 Universal stress protein family AIG1 PF04548.16 KXZ44455.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.6 1 1 0 1 1 1 0 AIG1 family Cytochrom_C1 PF02167.15 KXZ44456.1 - 4.7e-91 304.4 0.0 5.8e-91 304.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.21 KXZ44456.1 - 0.0031 18.6 1.2 0.019 16.1 1.2 2.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KXZ44456.1 - 0.0037 17.5 0.1 0.0088 16.3 0.1 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III TMEM138 PF14935.6 KXZ44457.1 - 0.00052 20.7 8.9 0.00052 20.7 8.9 1.5 2 0 0 2 2 2 1 Transmembrane protein 138 EF-hand_7 PF13499.6 KXZ44458.1 - 2.3e-12 47.2 0.1 6e-06 26.6 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ44458.1 - 4.1e-12 44.7 0.1 1.5e-06 27.3 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXZ44458.1 - 8.2e-11 40.9 0.0 0.0001 21.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KXZ44458.1 - 6.6e-09 34.9 0.0 0.00033 20.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXZ44458.1 - 4.2e-05 23.3 3.8 0.093 12.6 0.4 3.3 3 1 1 4 4 4 3 EF-hand domain pair Dockerin_1 PF00404.18 KXZ44458.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KXZ44458.1 - 0.089 13.1 0.0 4.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Bin3 PF06859.12 KXZ44459.1 - 2.8e-18 66.5 0.0 1.3e-17 64.4 0.0 1.9 1 1 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 KXZ44459.1 - 0.067 13.9 0.0 0.69 10.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DER1 PF04511.15 KXZ44460.1 - 3.6e-54 183.6 8.0 4e-54 183.4 8.0 1.0 1 0 0 1 1 1 1 Der1-like family Ubiquitin_2 PF14560.6 KXZ44461.1 - 1.2e-25 89.7 0.0 2.1e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KXZ44461.1 - 4.1e-21 74.8 2.4 6.4e-21 74.1 2.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain zf-GRF PF06839.12 KXZ44461.1 - 0.088 12.9 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 GRF zinc finger Dus PF01207.17 KXZ44463.1 - 2.2e-54 184.6 0.0 2e-47 161.8 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NPCBM_assoc PF10633.9 KXZ44464.1 - 0.0034 17.6 0.4 2.8 8.3 0.0 2.3 2 0 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase zf-SNAP50_C PF12251.8 KXZ44467.1 - 5e-35 121.0 0.0 6.2e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal HTH_Tnp_1 PF01527.20 KXZ44467.1 - 0.08 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Transposase SMC_N PF02463.19 KXZ44470.1 - 6e-53 179.5 0.1 2.9e-50 170.8 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXZ44470.1 - 5.2e-21 75.1 0.1 1.3e-20 73.8 0.1 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXZ44470.1 - 4.3e-15 56.3 0.1 8.7e-08 32.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ44470.1 - 7.9e-08 31.9 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KXZ44470.1 - 7.9e-08 32.4 0.0 7.9e-08 32.4 0.0 2.7 2 1 0 2 2 1 1 AAA ATPase domain KASH_CCD PF14662.6 KXZ44470.1 - 4.7e-05 23.3 23.8 4.7e-05 23.3 23.8 7.0 3 2 4 7 7 7 2 Coiled-coil region of CCDC155 or KASH AAA_23 PF13476.6 KXZ44470.1 - 0.0005 20.6 73.5 0.0025 18.3 36.7 6.1 3 2 0 3 3 2 1 AAA domain Spc7 PF08317.11 KXZ44470.1 - 0.0018 17.3 23.2 0.0018 17.3 23.2 6.6 3 2 3 6 6 6 4 Spc7 kinetochore protein SbcCD_C PF13558.6 KXZ44470.1 - 0.0053 17.0 0.0 0.026 14.8 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit TPR_MLP1_2 PF07926.12 KXZ44470.1 - 0.0082 16.2 16.7 0.0082 16.2 16.7 8.9 3 2 4 9 9 9 3 TPR/MLP1/MLP2-like protein ABC_tran PF00005.27 KXZ44470.1 - 0.15 12.6 0.0 0.15 12.6 0.0 5.1 4 3 0 4 4 3 0 ABC transporter ATG16 PF08614.11 KXZ44470.1 - 1.1 9.5 110.1 0.035 14.3 6.6 5.9 4 1 1 5 5 5 0 Autophagy protein 16 (ATG16) YojJ PF10372.9 KXZ44470.1 - 5.3 7.2 9.7 2.6 8.2 0.0 4.6 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus U-box PF04564.15 KXZ44471.1 - 5.1e-14 52.2 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain Myc_N PF01056.18 KXZ44471.1 - 3.6 7.4 6.1 7.6 6.3 6.1 1.5 1 0 0 1 1 1 0 Myc amino-terminal region ATP-synt PF00231.19 KXZ44472.1 - 2.1e-73 247.5 2.5 2.4e-73 247.3 2.5 1.0 1 0 0 1 1 1 1 ATP synthase MafB PF06255.13 KXZ44472.1 - 0.031 13.7 0.3 0.053 13.0 0.3 1.3 1 0 0 1 1 1 0 Neisseria toxin MafB Peptidase_M8 PF01457.16 KXZ44474.1 - 5.6e-14 51.7 0.1 2.1e-06 26.7 0.0 2.5 3 0 0 3 3 3 2 Leishmanolysin TFIIA PF03153.13 KXZ44474.1 - 4.1 7.3 4.2 6.1 6.7 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 KXZ44476.1 - 0.051 13.2 2.8 0.063 12.9 2.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4574 PF15141.6 KXZ44476.1 - 6.9 6.6 7.6 0.54 10.2 1.5 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF1151 PF06625.11 KXZ44477.1 - 0.21 11.5 7.8 0.42 10.6 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) CRR7 PF12095.8 KXZ44477.1 - 0.28 11.6 2.7 0.79 10.2 0.8 2.5 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 HAUS6_N PF14661.6 KXZ44477.1 - 0.82 9.2 8.9 1.9 8.0 7.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Enkurin PF13864.6 KXZ44477.1 - 0.83 10.1 7.8 21 5.6 7.2 2.3 2 0 0 2 2 2 0 Calmodulin-binding MAT1 PF06391.13 KXZ44477.1 - 1.7 8.4 6.6 2.6 7.8 6.6 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Syntaxin-6_N PF09177.11 KXZ44477.1 - 2.9 8.5 7.1 1.2 9.7 3.9 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Macoilin PF09726.9 KXZ44477.1 - 5.2 5.5 7.4 8 4.9 7.4 1.2 1 0 0 1 1 1 0 Macoilin family SAP PF02037.27 KXZ44478.1 - 4.8e-29 99.6 6.3 7.6e-06 25.6 0.1 5.6 5 0 0 5 5 5 5 SAP domain Dala_Dala_lig_N PF01820.21 KXZ44478.1 - 0.016 15.7 0.0 0.048 14.1 0.0 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Dala_Dala_lig_C PF07478.13 KXZ44478.1 - 0.098 12.2 0.0 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXZ44478.1 - 0.12 11.9 0.0 0.38 10.3 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain NAC PF01849.18 KXZ44479.1 - 2.4e-24 85.1 0.7 2.4e-24 85.1 0.7 2.2 3 0 0 3 3 3 1 NAC domain PGA2 PF07543.12 KXZ44479.1 - 0.14 12.2 11.8 1.4 8.9 0.6 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 CDC45 PF02724.14 KXZ44479.1 - 0.35 9.1 14.4 0.89 7.8 8.1 2.0 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.13 KXZ44479.1 - 0.46 10.6 18.5 1.3 9.1 18.1 1.8 1 1 0 1 1 1 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 KXZ44479.1 - 0.5 10.8 12.4 0.38 11.2 6.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KXZ44479.1 - 1.5 9.2 14.0 1.7 9.1 9.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 4HBT PF03061.22 KXZ44480.1 - 0.00062 20.1 0.0 0.0018 18.6 0.0 1.9 1 1 0 1 1 1 1 Thioesterase superfamily Myb_DNA-bind_7 PF15963.5 KXZ44482.1 - 1.2e-21 76.4 0.0 2.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KXZ44482.1 - 0.03 14.5 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.25 KXZ44483.1 - 2.8e-23 82.6 0.0 4.3e-21 75.5 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44483.1 - 1.2e-08 34.6 0.0 6.2e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase 2_5_RNA_ligase2 PF13563.6 KXZ44483.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily CxxCxxCC PF03692.15 KXZ44484.1 - 2.2e-07 31.5 0.0 4.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain HTH_3 PF01381.22 KXZ44484.1 - 0.0064 16.5 0.1 4.9 7.3 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix HTH_19 PF12844.7 KXZ44484.1 - 0.031 14.3 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3533 PF12051.8 KXZ44485.1 - 3.1e-14 52.7 8.7 8.2e-14 51.3 8.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 KXZ44485.1 - 0.35 9.9 13.9 3.8 6.5 0.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein WW PF00397.26 KXZ44486.1 - 1.4e-13 50.7 5.1 7.7e-07 29.1 0.7 3.6 3 0 0 3 3 3 2 WW domain Ank_2 PF12796.7 KXZ44486.1 - 2.5e-07 31.2 0.1 4.4e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44486.1 - 5.9e-07 29.9 0.1 0.0035 17.9 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44486.1 - 5.2e-06 26.6 0.8 0.01 16.2 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44486.1 - 0.00023 21.3 0.5 0.044 14.3 0.1 3.1 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXZ44486.1 - 0.00033 21.0 1.1 0.0023 18.3 0.4 2.4 2 0 0 2 2 2 1 Ankyrin repeat PQQ PF01011.21 KXZ44486.1 - 0.0041 17.0 0.3 0.64 10.0 0.0 3.7 4 0 0 4 4 4 1 PQQ enzyme repeat Collagen_bind_2 PF12904.7 KXZ44486.1 - 0.0068 16.4 0.1 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 Putative collagen-binding domain of a collagenase Glyco_hyd_101C PF17451.2 KXZ44486.1 - 0.1 12.9 1.1 0.7 10.2 0.6 2.4 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain PrmA PF06325.13 KXZ44487.1 - 2.7e-07 30.3 0.0 4.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXZ44487.1 - 3.1e-07 31.0 0.0 6.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ44487.1 - 3e-05 23.6 0.0 7.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KXZ44487.1 - 9.4e-05 23.0 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KXZ44487.1 - 0.0002 21.3 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 KXZ44487.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KXZ44487.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 KXZ44487.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fis1_TPR_C PF14853.6 KXZ44488.1 - 1.2e-15 57.3 0.3 2e-15 56.6 0.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KXZ44488.1 - 3e-09 36.4 0.1 6.1e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KXZ44488.1 - 0.00025 21.2 0.4 0.00033 20.8 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KXZ44488.1 - 0.0063 16.8 0.1 0.012 15.9 0.0 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4100 PF13352.6 KXZ44488.1 - 0.014 15.2 0.1 0.019 14.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4100) TPR_19 PF14559.6 KXZ44488.1 - 0.038 14.5 0.1 0.081 13.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CCT PF06203.14 KXZ44490.1 - 1.9e-16 59.8 11.5 2.6e-16 59.4 11.5 1.2 1 0 0 1 1 1 1 CCT motif PDDEXK_6 PF04720.12 KXZ44491.1 - 8.3e-22 78.2 0.0 1.3e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 PDDEXK-like family of unknown function CM1 PF03026.15 KXZ44491.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M1 protein DUF1876 PF08962.11 KXZ44492.1 - 0.038 13.9 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) PseudoU_synth_2 PF00849.22 KXZ44494.1 - 5e-20 72.2 0.0 5.4e-19 68.8 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase Chlam_PMP PF02415.17 KXZ44496.1 - 1e-10 41.4 36.5 0.05 14.1 1.2 7.1 7 0 0 7 7 7 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Phage_spike PF18715.1 KXZ44496.1 - 0.12 12.5 14.7 1.3 9.1 0.6 5.2 4 1 0 4 4 4 0 Phage spike trimer Gp5_C PF06715.12 KXZ44496.1 - 0.21 11.8 9.3 8.2 6.8 0.4 4.7 5 0 0 5 5 5 0 Gp5 C-terminal repeat (3 copies) TRP PF06011.12 KXZ44497.1 - 1.8e-06 27.0 0.8 1.8e-06 27.0 0.8 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel Transposase_28 PF04195.12 KXZ44497.1 - 0.13 12.5 1.7 0.3 11.3 1.7 1.6 1 0 0 1 1 1 0 Putative gypsy type transposon TRP PF06011.12 KXZ44498.1 - 0.059 12.1 11.6 0.13 10.9 11.6 1.7 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ank_2 PF12796.7 KXZ44500.1 - 5.2e-59 196.8 19.3 1.6e-16 60.6 0.2 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44500.1 - 9.1e-56 185.6 18.1 7.6e-08 32.8 0.0 7.4 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44500.1 - 1.9e-48 156.8 12.2 1.6e-05 24.9 0.1 9.6 9 1 1 10 10 10 8 Ankyrin repeat Ank PF00023.30 KXZ44500.1 - 5.4e-48 159.4 33.4 8.8e-08 32.3 0.5 9.3 8 1 1 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 KXZ44500.1 - 1.2e-34 117.8 23.5 5e-07 29.9 0.3 8.8 1 1 8 9 9 9 8 Ankyrin repeats (many copies) HTH_16 PF12645.7 KXZ44500.1 - 0.013 15.6 7.3 18 5.5 0.0 5.9 6 0 0 6 6 6 0 Helix-turn-helix domain DUF1521 PF07481.11 KXZ44500.1 - 0.082 12.9 4.1 2.4 8.1 0.2 3.6 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1521) SnoaL_4 PF13577.6 KXZ44500.1 - 0.096 12.8 1.1 3.6 7.7 0.2 2.9 1 1 2 3 3 3 0 SnoaL-like domain Cas_VVA1548 PF09652.10 KXZ44500.1 - 0.18 12.1 0.7 95 3.3 0.0 3.7 4 1 0 4 4 4 0 Putative CRISPR-associated protein (Cas_VVA1548) PHD_3 PF13922.6 KXZ44500.1 - 6.1 7.3 5.9 25 5.4 0.3 3.8 3 2 0 4 4 4 0 PHD domain of transcriptional enhancer, Asx Ank_2 PF12796.7 KXZ44501.1 - 5.2e-80 264.1 20.8 2e-18 66.7 2.5 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44501.1 - 8.5e-71 233.5 28.0 2.3e-09 37.6 0.2 9.0 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44501.1 - 4.8e-64 204.7 11.2 0.00011 22.3 0.0 13.1 13 0 0 13 13 13 13 Ankyrin repeat Ank PF00023.30 KXZ44501.1 - 9.5e-62 202.9 36.6 1.4e-05 25.3 0.4 13.1 13 0 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.6 KXZ44501.1 - 8.1e-46 153.5 27.5 2.7e-06 27.5 0.0 10.7 2 1 10 12 12 12 12 Ankyrin repeats (many copies) HTH_16 PF12645.7 KXZ44501.1 - 0.1 12.7 12.8 30 4.7 0.0 6.3 7 0 0 7 7 7 0 Helix-turn-helix domain DUF3368 PF11848.8 KXZ44501.1 - 0.71 9.7 9.1 42 4.0 0.1 6.6 9 0 0 9 9 9 0 Domain of unknown function (DUF3368) FAD-SLDH PF12318.8 KXZ44501.1 - 2.7 8.0 13.2 7.2 6.6 0.2 3.9 1 1 4 5 5 5 0 Membrane bound FAD containing D-sorbitol dehydrogenase Imm_superinfect PF14373.6 KXZ44501.1 - 2.8 7.9 5.5 36 4.4 0.0 5.0 6 0 0 6 6 6 0 Superinfection immunity protein Transposase_28 PF04195.12 KXZ44503.1 - 0.16 12.2 1.8 0.64 10.3 0.7 2.6 3 0 0 3 3 3 0 Putative gypsy type transposon Chlam_PMP PF02415.17 KXZ44504.1 - 1.6e-05 25.1 72.0 0.075 13.5 0.9 10.7 10 1 0 10 10 10 7 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat L6_membrane PF05805.12 KXZ44504.1 - 0.41 10.2 0.1 0.41 10.2 0.1 2.3 2 1 1 3 3 3 0 L6 membrane protein Pkinase_Tyr PF07714.17 KXZ44505.1 - 1.3e-33 116.4 0.0 3.1e-20 72.6 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ44505.1 - 4.5e-31 108.2 0.0 9.3e-29 100.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ44505.1 - 0.00054 20.0 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ44505.1 - 0.022 13.7 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXZ44505.1 - 0.24 10.7 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 KXZ44506.1 - 1.8e-20 73.0 0.6 3.1e-11 43.6 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44506.1 - 3.5e-17 62.8 1.1 4.9e-16 59.1 0.9 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ44506.1 - 7e-16 58.1 1.7 2.7e-11 43.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44506.1 - 1.3e-14 53.9 0.2 6.1e-05 23.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KXZ44506.1 - 6.9e-12 44.5 0.0 0.00026 21.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat UBA PF00627.31 KXZ44506.1 - 0.05 13.5 3.4 4.8 7.2 0.4 2.3 2 0 0 2 2 2 0 UBA/TS-N domain Ank_2 PF12796.7 KXZ44507.1 - 3.4e-70 232.7 0.9 4.4e-19 68.9 0.0 5.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44507.1 - 1.1e-64 206.7 6.5 5e-06 26.5 0.0 11.2 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KXZ44507.1 - 7.6e-57 188.6 17.0 3.2e-05 24.1 0.0 10.3 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44507.1 - 1.3e-55 183.5 24.6 5.4e-06 26.6 0.0 10.9 10 1 1 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KXZ44507.1 - 2.7e-54 180.9 0.9 6.8e-11 42.5 0.0 6.9 5 1 1 6 6 6 6 Ankyrin repeats (many copies) COR PF16095.5 KXZ44507.1 - 1.9e-15 57.2 0.0 2.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain CdAMP_rec PF06153.11 KXZ44507.1 - 5e-05 23.5 0.0 0.91 9.8 0.0 3.8 2 1 2 4 4 4 1 Cyclic-di-AMP receptor DUF2384 PF09722.10 KXZ44507.1 - 0.033 14.2 5.1 79 3.4 0.0 7.3 10 0 0 10 10 10 0 Protein of unknown function (DUF2384) Roc PF08477.13 KXZ44507.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ArsP_1 PF03773.13 KXZ44507.1 - 0.39 9.8 5.7 27 3.8 0.1 4.1 3 1 0 4 4 4 0 Predicted permease Ank_2 PF12796.7 KXZ44508.1 - 3.7e-33 114.0 6.4 4.3e-18 65.7 1.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44508.1 - 2.5e-24 84.6 5.2 2e-06 28.0 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ44508.1 - 3.4e-22 78.5 0.7 3.8e-07 30.5 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44508.1 - 4e-22 75.9 0.6 1.5e-05 25.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ44508.1 - 2.7e-20 72.2 9.3 3.4e-07 30.4 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) HTH_16 PF12645.7 KXZ44508.1 - 0.1 12.7 1.5 22 5.2 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain FemAB_like PF04339.12 KXZ44508.1 - 0.14 11.3 0.3 7.3 5.6 0.0 2.1 1 1 1 2 2 2 0 Peptidogalycan biosysnthesis/recognition Ank_2 PF12796.7 KXZ44509.1 - 1.6e-57 192.1 22.0 6.7e-20 71.5 1.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44509.1 - 4.7e-50 167.3 27.3 8.3e-10 39.0 0.2 6.2 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44509.1 - 8.3e-48 154.8 7.4 4.4e-05 23.6 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 KXZ44509.1 - 1.2e-46 155.1 27.6 1.8e-06 28.2 0.4 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 KXZ44509.1 - 1e-34 118.1 21.9 2.2e-07 31.0 0.1 5.7 1 1 6 7 7 7 7 Ankyrin repeats (many copies) DUF433 PF04255.14 KXZ44509.1 - 5.6e-05 22.9 0.1 13 5.7 0.0 5.3 6 0 0 6 6 6 1 Protein of unknown function (DUF433) Zwint PF15556.6 KXZ44509.1 - 0.016 14.7 0.5 1.1 8.7 0.0 2.4 2 1 0 2 2 2 0 ZW10 interactor Calponin PF00402.18 KXZ44509.1 - 0.024 14.3 4.3 48 3.7 0.0 4.4 4 0 0 4 4 4 0 Calponin family repeat FemAB_like PF04339.12 KXZ44509.1 - 0.027 13.6 0.9 15 4.6 0.0 3.3 2 1 1 3 3 3 0 Peptidogalycan biosysnthesis/recognition La_HTH_kDCL PF18177.1 KXZ44509.1 - 0.16 12.3 0.1 87 3.5 0.0 3.5 2 1 1 3 3 3 0 La HTH in kinetoplastid DICER domain Glyoxalase_4 PF13669.6 KXZ44509.1 - 0.23 11.8 4.5 36 4.7 0.0 3.7 1 1 2 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ABC2_membrane PF01061.24 KXZ44511.1 - 0.011 15.2 4.0 0.013 15.0 4.0 1.1 1 0 0 1 1 1 0 ABC-2 type transporter DUF2975 PF11188.8 KXZ44511.1 - 0.069 13.0 1.5 0.089 12.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Ank_2 PF12796.7 KXZ44512.1 - 1.7e-57 192.0 4.1 5.6e-15 55.7 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44512.1 - 5.9e-51 170.2 2.1 2.8e-11 43.7 0.0 4.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44512.1 - 6.6e-50 165.5 9.1 9.7e-06 25.8 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 KXZ44512.1 - 2.5e-44 144.1 0.1 2e-05 24.6 0.0 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 KXZ44512.1 - 1.4e-31 108.2 8.4 2.9e-08 33.8 0.1 6.7 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44512.1 - 0.0053 16.4 6.9 48 3.7 0.0 6.2 6 0 0 6 6 6 0 Calponin family repeat Imm_superinfect PF14373.6 KXZ44512.1 - 5.3 7.0 8.6 6.3 6.8 0.0 4.5 5 1 1 6 6 6 0 Superinfection immunity protein Ank_2 PF12796.7 KXZ44513.1 - 1.1e-47 160.5 13.2 1.7e-14 54.2 0.2 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44513.1 - 5.2e-41 138.5 5.0 4.3e-09 36.7 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44513.1 - 8.9e-29 98.7 12.1 3.8e-05 23.9 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KXZ44513.1 - 2.9e-25 85.6 0.6 0.0031 17.9 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KXZ44513.1 - 9.3e-23 80.0 7.5 0.00095 19.4 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) JmjC PF02373.22 KXZ44514.1 - 1.3e-06 28.8 0.0 2.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.11 KXZ44514.1 - 0.058 12.7 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_4 PF08007.12 KXZ44514.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 KXZ44514.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Cupin_8 PF13621.6 KXZ44514.1 - 0.17 11.6 1.3 0.41 10.3 1.0 1.8 2 1 0 2 2 2 0 Cupin-like domain Ank_4 PF13637.6 KXZ44516.1 - 1.9e-57 190.9 19.0 8.5e-14 51.7 0.1 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44516.1 - 2.8e-57 191.2 17.3 1.9e-18 66.8 2.9 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44516.1 - 9e-54 177.7 31.1 1.7e-08 34.6 0.1 8.0 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 KXZ44516.1 - 1.5e-51 166.4 9.2 7.2e-06 26.0 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 KXZ44516.1 - 2.6e-41 139.2 37.5 6e-10 39.2 0.4 7.4 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44516.1 - 3.6e-05 23.3 17.2 46 3.8 0.0 8.2 8 0 0 8 8 8 0 Calponin family repeat DUF2170 PF09938.9 KXZ44516.1 - 0.15 11.8 0.0 61 3.3 0.0 4.0 3 2 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2170) DUF1018 PF06252.12 KXZ44516.1 - 0.85 10.6 5.7 21 6.1 0.1 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) PPK2 PF03976.14 KXZ44516.1 - 1.2 8.6 8.6 1.1 8.7 0.3 3.2 1 1 1 3 3 3 0 Polyphosphate kinase 2 (PPK2) HTH_16 PF12645.7 KXZ44516.1 - 1.5 9.0 15.6 38 4.4 0.0 6.2 8 0 0 8 8 8 0 Helix-turn-helix domain DUF1593 PF07632.11 KXZ44516.1 - 6.4 6.1 6.4 29 4.0 0.2 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF1593) Ank_2 PF12796.7 KXZ44517.1 - 4.8e-09 36.7 0.1 5.9e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44517.1 - 2.3e-08 33.6 0.0 7.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXZ44517.1 - 1.1e-07 32.2 0.0 1.4e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44517.1 - 2.8e-07 30.7 0.3 6.1e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXZ44517.1 - 4.8e-07 29.9 0.6 2e-05 24.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44518.1 - 4.9e-85 280.2 37.7 7.6e-14 52.1 1.6 6.2 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44518.1 - 2.6e-49 159.4 7.5 0.00041 20.6 0.0 11.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KXZ44518.1 - 6.5e-48 160.5 8.4 1e-08 35.5 0.2 7.7 4 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44518.1 - 3.7e-47 156.8 33.2 3.6e-05 24.0 0.3 11.6 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.6 KXZ44518.1 - 6.7e-38 128.3 18.4 9.5e-09 35.4 0.1 8.0 3 2 5 9 9 9 8 Ankyrin repeats (many copies) COR PF16095.5 KXZ44518.1 - 3e-19 69.6 0.0 4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Calponin PF00402.18 KXZ44518.1 - 3.8 7.2 4.7 3e+02 1.2 0.0 4.2 4 0 0 4 4 4 0 Calponin family repeat Ank_2 PF12796.7 KXZ44519.1 - 1.6e-33 115.1 2.2 2.9e-17 63.0 0.3 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44519.1 - 1.7e-28 95.5 0.7 6.6e-05 23.0 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KXZ44519.1 - 3.1e-25 88.2 2.8 5.2e-07 30.1 0.0 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44519.1 - 7.3e-23 80.0 8.0 0.00014 22.1 0.1 5.7 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXZ44519.1 - 2.8e-16 59.3 6.9 1.8e-06 28.1 0.4 4.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) GATase_7 PF13537.6 KXZ44519.1 - 0.063 13.2 0.0 1e+02 2.8 0.0 3.8 3 1 1 4 4 4 0 Glutamine amidotransferase domain YdfZ PF14001.6 KXZ44519.1 - 0.25 11.8 3.4 14 6.2 0.1 3.7 4 0 0 4 4 4 0 YdfZ protein UBA PF00627.31 KXZ44519.1 - 0.65 10.0 30.6 3.6 7.6 0.6 5.9 6 0 0 6 6 6 0 UBA/TS-N domain Calponin PF00402.18 KXZ44519.1 - 1.6 8.4 9.7 37 4.1 0.0 4.3 6 0 0 6 6 6 0 Calponin family repeat Ank PF00023.30 KXZ44520.1 - 2.2e-18 65.8 0.3 7.2e-09 35.7 0.0 3.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXZ44520.1 - 1.2e-14 54.7 0.0 4.2e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ44520.1 - 3e-14 52.9 0.0 1.6e-07 31.5 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ44520.1 - 3.4e-13 49.8 0.0 1.2e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44520.1 - 3.3e-12 45.4 0.0 3.4e-06 27.0 0.0 3.0 3 1 0 3 3 3 2 Ankyrin repeat Roc PF08477.13 KXZ44520.1 - 1.1e-10 41.7 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ44520.1 - 1e-05 25.1 0.0 0.00011 21.7 0.0 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXZ44520.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Ras family AAA_25 PF13481.6 KXZ44520.1 - 0.0041 16.7 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXZ44520.1 - 0.018 15.4 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXZ44520.1 - 0.036 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KXZ44520.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KXZ44520.1 - 0.077 12.3 0.1 0.41 9.9 0.1 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KXZ44520.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KXZ44520.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ44520.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 KXZ44520.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit COR PF16095.5 KXZ44521.1 - 9.6e-14 51.6 0.1 7.9e-08 32.3 0.0 3.1 2 1 1 3 3 3 2 C-terminal of Roc, COR, domain PSII_Pbs27 PF13326.6 KXZ44521.1 - 0.2 12.0 0.2 0.67 10.3 0.0 2.0 2 0 0 2 2 2 0 Photosystem II Pbs27 NUP214 PF16755.5 KXZ44521.1 - 0.47 9.6 5.9 0.77 8.9 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 CSTF_C PF14304.6 KXZ44521.1 - 1 9.0 5.0 3.4 7.3 0.5 2.7 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Med4 PF10018.9 KXZ44521.1 - 3.7 7.2 5.5 7.6 6.2 5.5 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Roc PF08477.13 KXZ44523.1 - 3.3e-18 66.0 0.0 5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_5 PF13857.6 KXZ44523.1 - 3e-16 59.3 1.6 7.7e-10 38.8 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) COR PF16095.5 KXZ44523.1 - 9.2e-15 55.0 0.0 1.3e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_2 PF12796.7 KXZ44523.1 - 1.6e-14 54.2 0.0 2.3e-09 37.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44523.1 - 3.7e-14 52.4 2.7 0.00012 22.3 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXZ44523.1 - 2.9e-13 50.0 0.1 8.2e-06 26.3 0.0 3.8 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ras PF00071.22 KXZ44523.1 - 6.6e-09 35.6 0.0 1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Ank_3 PF13606.6 KXZ44523.1 - 6.7e-09 35.3 0.0 0.03 14.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Arf PF00025.21 KXZ44523.1 - 6.5e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXZ44523.1 - 0.007 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KXZ44523.1 - 0.032 14.4 0.0 0.09 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KXZ44523.1 - 0.053 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KXZ44523.1 - 0.096 13.1 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 KXZ44523.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ank_4 PF13637.6 KXZ44524.1 - 4.3e-57 189.8 21.8 5.6e-10 39.5 0.1 7.0 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44524.1 - 3.5e-51 171.7 18.0 7.9e-16 58.4 1.9 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44524.1 - 3.7e-47 156.8 30.7 3.2e-07 30.5 0.1 9.1 7 2 2 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 KXZ44524.1 - 1.3e-41 135.7 11.5 1.3e-05 25.1 0.0 8.9 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KXZ44524.1 - 8.9e-33 111.9 22.0 2e-07 31.1 0.4 7.7 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44524.1 - 0.00096 18.7 10.4 54 3.6 0.0 6.3 6 0 0 6 6 6 0 Calponin family repeat HTH_16 PF12645.7 KXZ44524.1 - 0.27 11.3 14.6 21 5.3 0.1 6.0 7 0 0 7 7 7 0 Helix-turn-helix domain DUF3368 PF11848.8 KXZ44524.1 - 0.98 9.3 5.3 2.5e+02 1.6 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3368) Ank_2 PF12796.7 KXZ44525.1 - 8.3e-39 132.1 0.5 2.8e-10 40.6 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44525.1 - 1.1e-27 93.0 0.4 0.0016 18.8 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KXZ44525.1 - 1.5e-27 94.8 17.1 9.3e-05 22.7 0.1 8.1 8 1 0 8 8 7 5 Ankyrin repeat Ank_5 PF13857.6 KXZ44525.1 - 3.2e-24 84.7 4.5 1.2e-08 35.1 0.1 6.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ44525.1 - 7.4e-24 83.8 1.7 2.3e-09 37.6 0.0 5.2 4 2 2 6 6 5 4 Ankyrin repeats (many copies) Roc PF08477.13 KXZ44525.1 - 6.7e-20 71.5 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ44525.1 - 4.5e-13 49.1 0.0 7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Ras family COR PF16095.5 KXZ44525.1 - 6.7e-10 39.1 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Arf PF00025.21 KXZ44525.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXZ44525.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KXZ44525.1 - 0.022 15.1 0.0 0.11 12.9 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KXZ44525.1 - 0.026 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2514 PF10721.9 KXZ44525.1 - 0.22 11.5 11.4 2.4 8.2 3.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Ank_2 PF12796.7 KXZ44526.1 - 1.6e-43 147.2 0.1 2.8e-18 66.3 0.0 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44526.1 - 1.2e-39 133.1 7.5 1.7e-06 28.2 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KXZ44526.1 - 5.7e-34 116.1 0.1 1.8e-09 37.9 0.0 4.8 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44526.1 - 1.5e-33 111.0 0.0 6e-05 23.1 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KXZ44526.1 - 7.2e-31 105.9 5.9 9.3e-09 35.4 0.1 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) ABC_tran PF00005.27 KXZ44526.1 - 0.00024 21.7 0.0 0.00052 20.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Ank_2 PF12796.7 KXZ44527.1 - 5.4e-79 260.8 15.1 3.3e-14 53.2 0.5 6.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44527.1 - 6e-66 216.2 27.4 9e-07 29.1 0.1 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 KXZ44527.1 - 2.4e-64 212.9 7.8 2.1e-10 40.9 0.1 9.2 7 2 3 10 10 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44527.1 - 8.7e-62 197.8 10.2 1.7e-05 24.8 0.0 12.7 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 KXZ44527.1 - 2.9e-47 158.1 34.5 5.5e-11 42.5 0.3 9.5 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Roc PF08477.13 KXZ44527.1 - 5.1e-19 68.7 0.0 8.1e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ44527.1 - 1.3e-11 44.4 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ44527.1 - 5.2e-08 32.5 0.0 9.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family COR PF16095.5 KXZ44527.1 - 2e-07 31.0 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain DUF1604 PF07713.13 KXZ44527.1 - 0.004 17.0 4.5 94 2.9 0.0 6.2 2 2 4 6 6 6 0 Protein of unknown function (DUF1604) SRPRB PF09439.10 KXZ44527.1 - 0.0056 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXZ44527.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Sulfotransfer_4 PF17784.1 KXZ44527.1 - 0.089 12.6 0.1 16 5.2 0.0 3.9 1 1 3 5 5 5 0 Sulfotransferase domain AAA_33 PF13671.6 KXZ44527.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_16 PF12645.7 KXZ44527.1 - 2.7 8.1 19.7 1.7e+02 2.3 0.1 7.7 8 0 0 8 8 8 0 Helix-turn-helix domain Calponin PF00402.18 KXZ44527.1 - 6.7 6.4 8.3 3.2e+02 1.1 0.0 5.5 6 0 0 6 6 6 0 Calponin family repeat DUF4129 PF13559.6 KXZ44527.1 - 9.3 6.6 14.8 16 5.9 0.7 5.9 5 2 0 5 5 4 0 Domain of unknown function (DUF4129) Ank PF00023.30 KXZ44528.1 - 1.1e-14 54.1 2.7 2.8e-07 30.7 0.2 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXZ44528.1 - 1.6e-14 54.1 0.5 1.6e-13 50.9 0.2 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44528.1 - 2.7e-12 45.7 0.6 1.6e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXZ44528.1 - 4.7e-12 46.3 0.6 6.4e-12 45.9 0.6 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ44528.1 - 3.1e-11 43.3 3.6 5.3e-06 26.6 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Merozoite_SPAM PF07133.11 KXZ44528.1 - 0.082 12.9 0.0 9.3 6.2 0.0 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) UBA PF00627.31 KXZ44528.1 - 0.13 12.2 2.0 4.1 7.4 0.1 2.2 2 0 0 2 2 2 0 UBA/TS-N domain Ank PF00023.30 KXZ44529.1 - 8.7e-08 32.3 0.1 1.6e-07 31.4 0.1 1.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXZ44529.1 - 3.6e-07 29.9 0.0 5.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KXZ44529.1 - 1.5e-06 28.7 0.0 1.9e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44529.1 - 6.2e-06 26.7 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44529.1 - 0.0006 20.1 0.0 0.00088 19.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44530.1 - 2.2e-121 396.7 20.5 4.3e-18 65.7 0.0 7.4 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44530.1 - 2e-77 254.6 23.4 1.1e-10 41.8 0.0 11.6 4 3 9 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44530.1 - 2.4e-77 252.2 35.5 8.7e-07 29.1 0.1 15.2 15 1 0 15 15 15 12 Ankyrin repeat Ank_3 PF13606.6 KXZ44530.1 - 1.2e-65 209.6 4.5 6.6e-05 23.0 0.0 14.6 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.6 KXZ44530.1 - 6.4e-62 204.8 19.0 4.8e-09 36.3 0.1 11.4 2 1 10 12 12 12 12 Ankyrin repeats (many copies) Roc PF08477.13 KXZ44530.1 - 5.9e-10 39.4 0.0 1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ44530.1 - 1.8e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KXZ44530.1 - 0.00041 19.9 0.0 0.00065 19.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXZ44530.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 KXZ44530.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Gtr1_RagA PF04670.12 KXZ44530.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Calponin PF00402.18 KXZ44530.1 - 1.3 8.7 7.1 1.3e+02 2.3 0.0 5.1 6 0 0 6 6 6 0 Calponin family repeat ABC2_membrane PF01061.24 KXZ44531.1 - 0.015 14.8 2.1 0.024 14.1 2.1 1.3 1 0 0 1 1 1 0 ABC-2 type transporter ABC_tran PF00005.27 KXZ44532.1 - 8e-13 49.1 0.0 5.7e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Ank_2 PF12796.7 KXZ44533.1 - 9.7e-31 106.2 1.9 3.5e-11 43.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44533.1 - 3.2e-29 100.9 3.5 1.6e-10 41.3 0.0 4.4 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44533.1 - 7.1e-26 87.4 1.2 9e-05 22.6 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KXZ44533.1 - 1.7e-25 88.3 14.5 7.4e-07 29.3 0.3 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXZ44533.1 - 1.7e-21 76.0 5.3 2.6e-08 34.0 0.1 5.6 3 1 3 6 6 5 3 Ankyrin repeats (many copies) Roc PF08477.13 KXZ44533.1 - 1.1e-20 74.0 0.0 1.8e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ44533.1 - 1.7e-12 47.5 0.0 2.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 KXZ44533.1 - 3.4e-11 43.0 0.0 5.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ras family AAA_25 PF13481.6 KXZ44533.1 - 3.3e-05 23.5 0.2 0.4 10.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain Arf PF00025.21 KXZ44533.1 - 4.3e-05 23.0 0.0 7.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXZ44533.1 - 0.00019 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.21 KXZ44533.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXZ44533.1 - 0.0018 18.5 0.1 0.0088 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ44533.1 - 0.002 18.5 0.0 0.06 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KXZ44533.1 - 0.0023 18.4 0.0 0.0048 17.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.12 KXZ44533.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ44533.1 - 0.029 14.6 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KXZ44533.1 - 0.031 13.7 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXZ44533.1 - 0.055 13.6 0.0 0.25 11.4 0.0 2.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KXZ44533.1 - 0.098 12.6 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_28 PF13521.6 KXZ44533.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXZ44533.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 KXZ44533.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 KXZ44533.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KXZ44533.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 KXZ44533.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KXZ44533.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ44533.1 - 0.14 12.6 0.0 0.5 10.8 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXZ44533.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXZ44533.1 - 0.2 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 KXZ44535.1 - 3e-61 204.0 19.5 3.9e-19 69.0 4.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44535.1 - 4.5e-58 192.9 22.0 7.5e-11 42.3 0.2 6.2 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44535.1 - 1.6e-54 180.1 29.5 9.9e-06 25.8 0.3 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 KXZ44535.1 - 4.4e-51 164.9 9.3 0.00016 21.8 0.1 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 KXZ44535.1 - 5.3e-37 125.4 22.7 6.8e-10 39.0 0.8 6.7 2 2 4 7 7 7 7 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44535.1 - 0.032 13.9 14.9 68 3.2 0.0 7.0 7 0 0 7 7 7 0 Calponin family repeat baeRF_family5 PF18846.1 KXZ44535.1 - 0.079 13.2 0.9 13 6.0 0.0 4.1 4 1 1 5 5 5 0 Bacterial archaeo-eukaryotic release factor family 5 FemAB_like PF04339.12 KXZ44535.1 - 0.096 11.8 9.0 16 4.5 0.3 4.9 3 1 2 6 6 6 0 Peptidogalycan biosysnthesis/recognition PhoPQ_related PF10142.9 KXZ44535.1 - 0.26 9.9 2.3 7.6 5.1 0.1 3.9 3 2 3 6 6 6 0 PhoPQ-activated pathogenicity-related protein Glyoxalase_4 PF13669.6 KXZ44535.1 - 0.77 10.1 7.8 4.8 7.5 0.6 3.9 1 1 3 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1521 PF07481.11 KXZ44535.1 - 0.83 9.6 13.4 48 3.9 0.0 5.8 1 1 5 7 7 7 0 Domain of Unknown Function (DUF1521) DUF1499 PF07386.11 KXZ44535.1 - 1.4 9.5 4.4 1e+02 3.4 0.1 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1499) Peptidase_M60 PF13402.6 KXZ44535.1 - 1.9 7.9 6.1 72 2.8 0.3 4.0 4 0 0 4 4 4 0 Peptidase M60, enhancin and enhancin-like Secretin_N PF03958.17 KXZ44535.1 - 4.3 7.8 10.8 21 5.6 2.4 3.9 2 2 0 2 2 2 0 Bacterial type II/III secretion system short domain HTH_16 PF12645.7 KXZ44535.1 - 5.3 7.2 17.5 66 3.7 0.1 6.4 7 0 0 7 7 7 0 Helix-turn-helix domain eIF2_C PF09173.11 KXZ44536.1 - 6.4e-36 122.5 0.4 1.5e-35 121.3 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KXZ44536.1 - 4.1e-24 85.2 0.7 3.7e-23 82.1 0.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXZ44536.1 - 7.2e-11 42.3 0.7 1.7e-10 41.2 0.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ44536.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXZ44536.1 - 0.002 18.1 0.5 0.029 14.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase YdjO PF14169.6 KXZ44536.1 - 0.0028 17.3 0.1 0.0062 16.2 0.1 1.5 1 0 0 1 1 1 1 Cold-inducible protein YdjO MMR_HSR1_Xtn PF16897.5 KXZ44536.1 - 0.069 13.2 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Promethin PF16015.5 KXZ44537.1 - 0.16 11.9 10.5 0.29 11.1 1.8 2.3 1 1 1 2 2 2 0 Promethin Ndc80_HEC PF03801.13 KXZ44538.1 - 6.4e-46 155.8 0.8 1.7e-45 154.4 0.0 2.1 3 0 0 3 3 3 1 HEC/Ndc80p family DUF5595 PF18077.1 KXZ44538.1 - 0.00058 19.9 0.4 0.00058 19.9 0.4 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF5595) MAD PF05557.13 KXZ44538.1 - 0.025 13.0 19.4 0.037 12.4 19.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF641 PF04859.12 KXZ44538.1 - 0.54 10.6 21.6 1.3 9.3 8.9 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 KXZ44538.1 - 2 8.6 0.0 2 8.6 0.0 3.8 3 1 1 4 4 4 0 bZIP transcription factor UPF0242 PF06785.11 KXZ44538.1 - 3 7.9 24.0 4.4 7.4 23.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sec34 PF04136.15 KXZ44538.1 - 5.5 6.9 11.6 0.47 10.3 5.1 2.1 1 1 1 2 2 2 0 Sec34-like family FUSC PF04632.12 KXZ44538.1 - 6.2 5.2 12.9 9 4.7 12.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 KXZ44538.1 - 6.3 6.0 25.4 7.5 5.8 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FapA PF03961.13 KXZ44538.1 - 7.2 5.1 11.1 21 3.6 10.9 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF4455 PF14643.6 KXZ44539.1 - 3.4e-05 22.7 7.5 4.2e-05 22.4 7.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) DUF4407 PF14362.6 KXZ44539.1 - 0.0051 16.2 15.6 0.0061 15.9 15.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4404 PF14357.6 KXZ44539.1 - 0.0061 17.2 3.5 0.0061 17.2 3.5 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4404) Golgin_A5 PF09787.9 KXZ44539.1 - 0.0063 16.0 11.0 0.008 15.7 11.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Leu_zip PF15294.6 KXZ44539.1 - 0.01 15.4 9.8 0.016 14.7 9.8 1.3 1 1 0 1 1 1 0 Leucine zipper Phage_GP20 PF06810.11 KXZ44539.1 - 0.018 14.9 4.5 0.018 14.9 4.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 AAA_13 PF13166.6 KXZ44539.1 - 0.018 13.7 7.2 0.024 13.3 7.2 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 KXZ44539.1 - 0.026 13.6 8.2 0.027 13.6 8.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 KXZ44539.1 - 0.035 14.7 10.6 0.89 10.2 2.3 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4618 PF15397.6 KXZ44539.1 - 0.04 13.3 7.1 0.057 12.8 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) LMBR1 PF04791.16 KXZ44539.1 - 0.071 12.0 3.5 0.079 11.9 3.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SOAR PF16533.5 KXZ44539.1 - 0.15 12.1 8.4 0.2 11.6 7.6 1.8 1 1 0 1 1 1 0 STIM1 Orai1-activating region KASH_CCD PF14662.6 KXZ44539.1 - 0.17 11.7 11.9 0.61 9.9 11.3 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KXZ44539.1 - 0.17 10.8 16.6 0.38 9.6 16.5 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 KXZ44539.1 - 0.27 11.7 15.2 45 4.5 15.2 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Prefoldin_2 PF01920.20 KXZ44539.1 - 0.3 11.1 8.7 0.9 9.5 0.6 2.6 1 1 1 2 2 2 0 Prefoldin subunit Cnn_1N PF07989.11 KXZ44539.1 - 0.32 11.2 8.6 1.9 8.7 1.9 2.4 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Fez1 PF06818.15 KXZ44539.1 - 0.34 11.4 13.4 0.45 10.9 13.4 1.1 1 0 0 1 1 1 0 Fez1 M PF02370.16 KXZ44539.1 - 0.36 11.5 11.1 0.76 10.5 0.5 3.4 2 1 1 3 3 3 0 M protein repeat DUF1664 PF07889.12 KXZ44539.1 - 0.4 10.7 5.3 11 6.1 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.6 KXZ44539.1 - 1.2 9.1 7.2 5.2 7.1 1.3 2.2 1 1 1 2 2 2 0 FlxA-like protein V_ATPase_I PF01496.19 KXZ44539.1 - 1.3 6.9 4.2 1.4 6.7 4.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.8 KXZ44539.1 - 1.4 9.3 12.8 7.3 7.0 6.4 2.2 1 1 1 2 2 2 0 YlqD protein DUF3347 PF11827.8 KXZ44539.1 - 1.5 9.0 7.5 1.4 9.1 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Jnk-SapK_ap_N PF09744.9 KXZ44539.1 - 1.7 8.8 15.8 4.8 7.4 15.8 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 MCD_N PF17408.2 KXZ44539.1 - 2.6 8.2 5.4 3 8.0 1.0 2.8 1 1 2 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain IFP_35_N PF07334.13 KXZ44539.1 - 2.8 8.1 5.9 0.71 10.0 0.8 2.3 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus YabA PF06156.13 KXZ44539.1 - 3.5 8.3 7.1 54 4.5 6.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 KXZ44539.1 - 3.6 8.0 21.9 0.67 10.3 6.5 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3584 PF12128.8 KXZ44539.1 - 3.7 4.9 18.9 6.8 4.1 18.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.14 KXZ44539.1 - 4.3 7.7 20.5 2.5 8.4 8.3 2.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) COG2 PF06148.11 KXZ44539.1 - 9.3 6.3 10.1 4.3 7.4 3.0 3.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 KXZ44539.1 - 9.9 6.2 12.5 49 4.0 12.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2470 PF10615.9 KXZ44540.1 - 5.3e-15 55.8 0.0 6.8e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) ZZ PF00569.17 KXZ44542.1 - 1.4e-06 28.0 3.4 1.4e-06 28.0 3.4 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type zf-RING_4 PF14570.6 KXZ44542.1 - 1.7e-06 27.7 6.2 1.7e-06 27.7 6.2 2.6 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KXZ44542.1 - 0.0038 17.0 10.4 0.0038 17.0 10.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXZ44542.1 - 0.89 9.8 24.2 0.025 14.7 7.2 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXZ44542.1 - 2.3 8.3 19.1 0.72 9.9 3.3 3.6 3 0 0 3 3 3 0 RING-type zinc-finger HrpB7 PF09486.10 KXZ44543.1 - 0.0013 19.2 10.6 0.0013 19.2 10.6 3.0 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) Sporozoite_P67 PF05642.11 KXZ44543.1 - 0.1 10.6 1.5 0.13 10.4 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen COG2 PF06148.11 KXZ44543.1 - 0.83 9.7 2.8 0.71 10.0 0.7 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FGGY_C PF02782.16 KXZ44544.1 - 8.3e-11 42.0 0.0 1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Methyltransf_21 PF05050.12 KXZ44545.1 - 1.3e-11 44.8 0.2 5.6e-08 33.0 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase FkbM domain Met_10 PF02475.16 KXZ44545.1 - 0.02 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein SAM_MT PF04445.13 KXZ44545.1 - 0.068 12.6 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Ion_trans PF00520.31 KXZ44546.1 - 4e-17 62.3 4.8 5.8e-17 61.7 4.8 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KXZ44546.1 - 1.6e-10 40.9 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Helicase_C PF00271.31 KXZ44547.1 - 2.8e-10 40.5 0.0 5.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ44547.1 - 6.9e-05 22.9 0.0 0.0009 19.3 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXZ44547.1 - 0.00012 21.9 0.0 0.0012 18.6 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pro_isomerase PF00160.21 KXZ44548.1 - 1.2e-38 132.8 0.3 8.5e-19 68.4 0.0 2.0 1 1 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_2 PF12796.7 KXZ44549.1 - 6.2e-15 55.6 0.0 8.3e-08 32.7 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44549.1 - 2e-12 46.9 0.7 0.00067 20.0 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXZ44549.1 - 2.4e-12 45.9 0.7 0.013 16.0 0.0 5.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXZ44549.1 - 2.1e-11 44.1 0.6 0.00011 22.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44549.1 - 3.9e-11 43.0 2.4 0.0018 18.6 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Abhydrolase_1 PF00561.20 KXZ44549.1 - 1.4e-08 34.7 0.0 4.4e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-C3HC4_3 PF13920.6 KXZ44549.1 - 1.5e-08 34.4 5.9 2.6e-08 33.6 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ44549.1 - 0.00018 21.3 8.4 0.00033 20.5 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ44549.1 - 0.00029 21.1 9.8 0.00056 20.2 9.8 1.5 1 0 0 1 1 1 1 Ring finger domain Hydrolase_4 PF12146.8 KXZ44549.1 - 0.00071 18.9 0.0 0.0023 17.2 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 zf-RING_5 PF14634.6 KXZ44549.1 - 0.00095 19.1 7.3 0.0018 18.2 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXZ44549.1 - 0.0016 18.3 7.4 0.003 17.4 7.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ndr PF03096.14 KXZ44549.1 - 0.019 13.6 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family zf-C3HC4_2 PF13923.6 KXZ44549.1 - 0.1 12.5 9.4 0.24 11.3 9.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ44549.1 - 0.32 11.1 7.2 0.75 9.9 7.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Phage_GP20 PF06810.11 KXZ44550.1 - 0.00047 20.0 0.1 0.00057 19.7 0.1 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 KXZ44550.1 - 0.00092 19.3 0.6 0.0013 18.8 0.6 1.5 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 KXZ44550.1 - 0.011 15.8 0.1 0.018 15.1 0.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Med30 PF11315.8 KXZ44550.1 - 0.12 12.5 0.9 0.99 9.6 0.9 1.9 1 1 0 1 1 1 0 Mediator complex subunit 30 V_ATPase_I PF01496.19 KXZ44550.1 - 0.17 9.7 0.1 0.19 9.6 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2064 PF09837.9 KXZ44552.1 - 5.8e-26 90.7 0.2 8.6e-26 90.2 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) NTP_transf_3 PF12804.7 KXZ44552.1 - 8.6e-05 22.9 0.7 0.00015 22.2 0.7 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain CofC PF01983.16 KXZ44552.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like Asp_Glu_race PF01177.22 KXZ44552.1 - 0.21 11.4 0.0 0.55 10.0 0.0 1.6 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase ABC1 PF03109.16 KXZ44555.1 - 5e-27 94.4 0.0 1.2e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXZ44555.1 - 4.5e-05 23.5 3.1 0.00013 22.0 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXZ44555.1 - 0.0013 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KXZ44555.1 - 0.0058 16.0 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44555.1 - 0.13 11.5 0.0 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase Peptidase_M20 PF01546.28 KXZ44557.1 - 1.1e-22 80.7 0.0 2.6e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXZ44557.1 - 5.1e-06 26.4 0.0 9.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DSPn PF14671.6 KXZ44558.1 - 3e-22 79.6 0.2 2.5e-21 76.6 0.1 2.4 2 1 1 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KXZ44558.1 - 6.1e-14 52.0 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXZ44558.1 - 2.5e-05 24.0 0.0 0.00066 19.3 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXZ44558.1 - 0.063 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family EMG1 PF03587.14 KXZ44559.1 - 0.049 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase Gly_kinase PF02595.15 KXZ44559.1 - 0.13 11.2 0.1 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Glycerate kinase family Solute_trans_a PF03619.16 KXZ44560.1 - 3.4e-52 177.6 6.2 9e-39 133.6 4.4 2.1 1 1 1 2 2 2 2 Organic solute transporter Ostalpha Solute_trans_a PF03619.16 KXZ44561.1 - 4.3e-20 72.3 1.3 4.3e-20 72.3 1.3 1.7 2 0 0 2 2 2 1 Organic solute transporter Ostalpha DUF5453 PF17534.2 KXZ44561.1 - 0.0021 18.1 0.6 0.0024 17.8 0.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5453) Frag1 PF10277.9 KXZ44561.1 - 0.0077 15.8 0.4 0.0091 15.6 0.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Ank_2 PF12796.7 KXZ44562.1 - 2.6e-33 114.5 0.4 4.2e-14 52.9 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44562.1 - 5.4e-20 71.5 0.3 1.4e-09 38.3 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44562.1 - 4.2e-19 68.3 0.6 2e-08 34.3 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44562.1 - 5.6e-18 64.5 1.0 3e-06 27.4 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXZ44562.1 - 2.5e-17 61.2 0.2 3.8e-06 26.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Herpes_Helicase PF02689.14 KXZ44562.1 - 0.08 10.9 0.0 0.094 10.6 0.0 1.0 1 0 0 1 1 1 0 Helicase DUF4187 PF13821.6 KXZ44563.1 - 1.1e-17 63.6 1.9 2.5e-17 62.4 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KXZ44563.1 - 1.5e-06 27.9 0.7 4.6e-06 26.4 0.7 1.9 1 0 0 1 1 1 1 G-patch domain Polyketide_cyc PF03364.20 KXZ44564.1 - 7e-10 39.2 0.0 8.6e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Hemerythrin PF01814.23 KXZ44565.1 - 3.7e-07 30.8 4.8 0.00054 20.6 7.0 2.7 2 1 0 2 2 2 2 Hemerythrin HHE cation binding domain zf-C2H2_jaz PF12171.8 KXZ44566.1 - 2.5e-06 27.6 0.2 5.6e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXZ44566.1 - 0.02 15.3 0.1 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SE PF08491.10 KXZ44567.1 - 3.8e-103 344.3 0.0 5e-103 343.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KXZ44567.1 - 1.5e-12 47.5 0.0 3.4e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXZ44567.1 - 8.9e-09 35.4 0.3 1.7e-06 27.9 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ44567.1 - 1.8e-06 27.3 0.5 2e-05 23.8 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXZ44567.1 - 2e-05 24.7 0.5 5.7e-05 23.3 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXZ44567.1 - 2.2e-05 24.0 0.8 3.2e-05 23.5 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXZ44567.1 - 2.6e-05 23.5 0.3 3.6e-05 23.0 0.3 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXZ44567.1 - 0.00061 19.1 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXZ44567.1 - 0.0009 18.4 1.2 0.0013 17.8 0.3 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KXZ44567.1 - 0.0016 17.8 0.3 0.0028 16.9 0.0 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXZ44567.1 - 0.002 16.9 0.0 0.0026 16.5 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXZ44567.1 - 0.021 15.4 0.0 0.043 14.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXZ44567.1 - 0.23 10.3 0.0 1.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXZ44567.1 - 0.24 10.6 0.1 0.35 10.1 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KXZ44567.1 - 0.3 9.5 0.0 0.46 9.0 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor FAST_1 PF06743.15 KXZ44569.1 - 1.5e-15 56.9 1.3 0.0044 16.9 0.0 5.6 3 1 3 6 6 6 6 FAST kinase-like protein, subdomain 1 tRNA_U5-meth_tr PF05958.11 KXZ44570.1 - 2.3e-17 63.0 0.0 6.6e-08 31.9 0.0 2.3 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 KXZ44570.1 - 1.3e-10 41.8 2.5 2.5e-08 34.5 0.3 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ44570.1 - 6.8e-09 35.7 0.1 1.3e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44570.1 - 3.1e-05 24.5 2.3 0.00012 22.6 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXZ44570.1 - 3.7e-05 23.4 1.1 4.8e-05 23.0 0.2 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KXZ44570.1 - 0.00043 20.0 0.0 0.00087 19.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KXZ44570.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KXZ44570.1 - 0.0043 16.5 0.2 0.0066 15.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KXZ44570.1 - 0.0097 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXZ44570.1 - 0.0097 16.6 0.6 0.04 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 KXZ44570.1 - 0.024 14.3 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.11 KXZ44570.1 - 0.085 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.13 KXZ44570.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 N6_N4_Mtase PF01555.18 KXZ44570.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 DNA methylase DUF3138 PF11336.8 KXZ44570.1 - 9.7 4.7 12.5 1.8 7.1 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Pkinase PF00069.25 KXZ44571.1 - 1.2e-31 110.1 0.0 1.4e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44571.1 - 6.8e-20 71.4 0.0 8.6e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ44571.1 - 0.0044 17.0 0.0 0.26 11.2 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ44571.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf-DNL PF05180.12 KXZ44572.1 - 5.8e-09 35.8 0.1 8.8e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger Rubredoxin_2 PF18073.1 KXZ44572.1 - 0.007 16.1 4.1 0.81 9.5 1.0 2.2 2 0 0 2 2 2 2 Rubredoxin metal binding domain DUF35_N PF12172.8 KXZ44572.1 - 1.7 8.6 4.7 21 5.1 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) BicD PF09730.9 KXZ44573.1 - 0.0029 16.1 17.1 0.0039 15.7 17.1 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D HOOK PF05622.12 KXZ44573.1 - 0.01 14.0 15.4 0.085 11.0 1.3 2.2 1 1 1 2 2 2 0 HOOK protein JIP_LZII PF16471.5 KXZ44573.1 - 0.078 13.2 8.7 5.5 7.2 1.1 4.0 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II AAA_13 PF13166.6 KXZ44573.1 - 0.2 10.3 21.2 0.5 9.0 18.8 2.3 1 1 1 2 2 2 0 AAA domain Fib_alpha PF08702.10 KXZ44573.1 - 0.39 10.9 3.7 2.7 8.2 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KXZ44573.1 - 0.43 9.9 18.1 0.29 10.4 4.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TFIIA PF03153.13 KXZ44573.1 - 0.71 9.8 13.2 0.85 9.5 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tropomyosin_1 PF12718.7 KXZ44573.1 - 1.2 9.3 20.6 0.6 10.3 9.2 2.8 2 1 0 2 2 2 0 Tropomyosin like Filament PF00038.21 KXZ44573.1 - 1.2 8.6 25.7 1.4 8.5 7.5 2.7 1 1 2 3 3 3 0 Intermediate filament protein Arm-DNA-bind_5 PF17293.2 KXZ44573.1 - 1.5 9.3 3.5 3.5 8.1 0.2 2.6 1 1 2 3 3 3 0 Arm DNA-binding domain Fez1 PF06818.15 KXZ44573.1 - 1.6 9.1 23.0 1.6 9.2 6.7 2.1 1 1 1 2 2 2 0 Fez1 FUSC PF04632.12 KXZ44573.1 - 1.9 6.9 31.8 2.7 6.4 31.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 KXZ44573.1 - 2 8.5 8.4 3.6 7.6 8.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 KXZ44573.1 - 2.8 8.1 39.6 1.9 8.7 24.1 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 KXZ44573.1 - 4 6.9 11.4 12 5.3 11.4 1.7 1 1 0 1 1 1 0 Leucine zipper SAPS PF04499.15 KXZ44573.1 - 4.7 5.9 10.7 5.9 5.5 10.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1664 PF07889.12 KXZ44573.1 - 6 6.9 7.4 4.2 7.4 0.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KXZ44573.1 - 6.5 6.2 42.5 24 4.4 28.7 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TACC_C PF05010.14 KXZ44573.1 - 7.9 6.2 16.7 2.1 8.1 1.9 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4472 PF14739.6 KXZ44573.1 - 9.8 7.0 23.6 3.1 8.6 0.9 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF4381 PF14316.6 KXZ44574.1 - 0.0072 16.6 6.6 0.012 15.8 6.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF2681 PF10883.8 KXZ44574.1 - 0.011 16.2 5.4 0.014 15.8 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TOC159_MAD PF11886.8 KXZ44574.1 - 0.027 13.4 0.0 0.036 12.9 0.0 1.3 1 1 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain SUIM_assoc PF16619.5 KXZ44574.1 - 5.2 7.2 12.0 10 6.3 12.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 KXZ44576.1 - 0.02 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF2730 PF10805.8 KXZ44577.1 - 0.00098 19.2 0.5 0.0017 18.4 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) DUF2730 PF10805.8 KXZ44578.1 - 0.017 15.2 0.2 0.029 14.5 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) KH_1 PF00013.29 KXZ44579.1 - 1.5e-18 66.3 0.0 2.1e-07 30.7 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXZ44579.1 - 3e-05 23.8 0.0 0.00096 18.9 0.0 2.4 2 0 0 2 2 2 1 KH domain KH_5 PF13184.6 KXZ44579.1 - 0.12 12.5 0.4 20 5.4 0.0 2.5 2 0 0 2 2 2 0 NusA-like KH domain Acyltransferase PF01553.21 KXZ44581.1 - 9e-17 61.0 0.0 2.2e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase K_channel_TID PF07941.11 KXZ44581.1 - 0.0047 17.4 2.9 0.0092 16.4 2.9 1.4 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain PAS PF00989.25 KXZ44582.1 - 6.3e-16 58.4 0.0 0.00033 20.6 0.0 4.7 3 1 1 4 4 4 4 PAS fold PAS_9 PF13426.7 KXZ44582.1 - 6.3e-15 55.3 0.0 2.9e-06 27.5 0.0 4.6 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 KXZ44582.1 - 2.1e-09 37.6 0.0 0.98 9.7 0.0 4.7 4 0 0 4 4 4 4 PAS fold Pro_isomerase PF00160.21 KXZ44583.1 - 4.2e-37 127.9 0.0 5.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sulfate_transp PF00916.20 KXZ44585.1 - 3e-83 279.7 12.8 9.8e-60 202.3 1.3 2.2 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 KXZ44585.1 - 2.6e-23 81.9 0.0 4.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KXZ44585.1 - 0.0011 19.2 0.1 0.0024 18.2 0.1 1.5 1 0 0 1 1 1 1 STAS domain NAD_binding_3 PF03447.16 KXZ44585.1 - 0.055 14.1 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DMT_YdcZ PF04657.13 KXZ44585.1 - 1.3 9.3 14.7 2.9 8.2 0.0 3.3 3 1 1 4 4 4 0 Putative inner membrane exporter, YdcZ BNR PF02012.20 KXZ44586.1 - 0.76 10.0 0.0 0.76 10.0 0.0 2.3 2 0 0 2 2 2 0 BNR/Asp-box repeat AFG1_ATPase PF03969.16 KXZ44587.1 - 2.3e-60 204.4 0.0 2.3e-43 148.5 0.0 4.3 4 1 0 4 4 4 4 AFG1-like ATPase Bac_DnaA PF00308.18 KXZ44587.1 - 0.029 14.2 0.1 3.9 7.3 0.1 2.9 2 1 1 3 3 3 0 Bacterial dnaA protein AAA_22 PF13401.6 KXZ44587.1 - 0.063 13.5 0.5 1 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KXZ44587.1 - 0.23 11.9 0.2 2.8 8.4 0.1 2.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.16 KXZ44588.1 - 1.6e-47 162.2 35.1 1.6e-47 162.2 35.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TP6A_N PF04406.14 KXZ44589.1 - 1.7e-12 47.1 0.0 3.6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2722 PF10846.8 KXZ44589.1 - 0.00029 19.9 2.0 0.00034 19.7 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 KXZ44589.1 - 0.0025 17.4 8.9 0.0033 17.1 8.9 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 KXZ44589.1 - 0.0034 17.5 4.7 0.0049 16.9 4.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 KXZ44589.1 - 1.2 10.2 3.2 2.4 9.2 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA PF00004.29 KXZ44591.1 - 1.2e-32 113.1 0.0 4e-32 111.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ44591.1 - 6e-07 30.0 4.3 7e-06 26.5 0.9 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KXZ44591.1 - 6.7e-05 23.1 0.0 9.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXZ44591.1 - 8.2e-05 22.6 0.1 0.00038 20.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ44591.1 - 0.00021 21.5 0.3 0.02 15.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ44591.1 - 0.00024 21.5 0.0 0.00038 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXZ44591.1 - 0.00033 20.4 0.3 0.0011 18.8 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KXZ44591.1 - 0.00089 18.9 1.3 0.0026 17.4 1.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ44591.1 - 0.012 15.8 0.8 0.048 13.8 0.3 1.9 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 KXZ44591.1 - 0.016 15.4 0.9 0.059 13.6 0.6 1.8 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXZ44591.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KXZ44591.1 - 0.023 13.9 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 KXZ44591.1 - 0.024 14.4 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KXZ44591.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 KXZ44591.1 - 0.031 14.7 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXZ44591.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KXZ44591.1 - 0.088 12.7 0.3 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KXZ44591.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXZ44591.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXZ44591.1 - 0.14 12.0 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Gpr1_Fun34_YaaH PF01184.19 KXZ44592.1 - 4.7e-32 111.3 19.7 6e-32 110.9 19.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4560 PF15118.6 KXZ44592.1 - 0.081 12.8 1.7 0.31 10.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4560) Acetyltransf_6 PF13480.7 KXZ44594.1 - 0.061 13.5 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FHA PF00498.26 KXZ44595.1 - 0.00054 20.3 0.0 0.00084 19.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 KXZ44595.1 - 0.24 11.8 0.0 0.36 11.2 0.0 1.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Sod_Fe_N PF00081.22 KXZ44596.1 - 9.8e-07 29.2 0.0 0.00054 20.4 0.0 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, alpha-hairpin domain FAM199X PF15814.5 KXZ44598.1 - 5.1 6.1 4.8 6.9 5.6 4.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X PEPCK_ATP PF01293.20 KXZ44599.1 - 1.2e-207 690.2 0.0 1.4e-207 690.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KXZ44599.1 - 0.028 14.8 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXZ44599.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DAGK_cat PF00781.24 KXZ44600.1 - 1.5e-12 47.2 0.1 6.2e-12 45.2 0.1 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Xan_ur_permease PF00860.20 KXZ44601.1 - 8.9e-44 149.7 27.0 2.1e-26 92.5 12.2 2.4 2 0 0 2 2 2 2 Permease family DUF1771 PF08590.10 KXZ44602.1 - 0.24 11.8 4.3 8 6.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) RabGAP-TBC PF00566.18 KXZ44603.1 - 2.1e-16 60.2 0.1 3e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PEPCK_ATP PF01293.20 KXZ44604.1 - 3.6e-181 602.9 0.0 9.3e-169 562.0 0.0 2.3 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KXZ44604.1 - 0.03 14.7 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXZ44604.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPMT PF05724.11 KXZ44605.1 - 4.2e-09 36.4 0.0 5.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KXZ44605.1 - 1.1e-06 29.3 0.0 0.00011 22.8 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44605.1 - 9.6e-06 26.2 0.0 3.6e-05 24.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ44605.1 - 3.4e-05 24.5 0.0 4.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ44605.1 - 0.00067 19.5 0.0 0.00088 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KXZ44605.1 - 0.0033 17.2 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 KXZ44605.1 - 0.0063 16.3 0.0 0.0063 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ44605.1 - 0.047 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N_2 PF13602.6 KXZ44605.1 - 0.1 13.7 0.0 0.18 12.9 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Septin PF00735.18 KXZ44606.1 - 4.4e-17 62.3 0.0 6.7e-16 58.4 0.0 2.2 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 KXZ44606.1 - 0.12 11.9 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-MYND PF01753.18 KXZ44607.1 - 7.6e-07 29.1 10.0 2.4e-06 27.5 10.0 1.9 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ44608.1 - 3.5e-06 27.0 9.5 3.5e-06 27.0 9.5 1.8 2 0 0 2 2 2 1 MYND finger CBM_48 PF02922.18 KXZ44609.1 - 1.4e-14 54.2 0.0 3.4e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KXZ44609.1 - 5.9e-14 52.4 0.0 2.5e-10 40.4 0.0 2.7 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Glyco_hydro_31 PF01055.26 KXZ44609.1 - 0.024 13.8 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 hDGE_amylase PF14701.6 KXZ44609.1 - 0.22 10.5 0.0 0.33 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Hexapep PF00132.24 KXZ44610.1 - 9.5e-09 34.6 14.2 0.0016 18.1 0.3 4.4 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXZ44610.1 - 1.4e-08 34.7 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KXZ44610.1 - 2.7e-05 22.5 3.6 0.005 15.0 0.6 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 KXZ44610.1 - 0.00032 21.1 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KXZ44610.1 - 0.038 12.9 0.5 0.19 10.6 0.5 1.9 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 KXZ44610.1 - 0.53 10.1 15.7 1.6 8.6 1.3 4.3 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase RicinB_lectin_2 PF14200.6 KXZ44611.1 - 4.5e-09 36.9 1.4 5.6e-09 36.6 1.4 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ44611.1 - 1.1e-06 28.9 0.1 1.8e-06 28.2 0.1 1.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KXZ44611.1 - 0.037 13.6 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain EF-hand_1 PF00036.32 KXZ44612.1 - 3.4e-05 23.1 0.0 7.9e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ44612.1 - 0.0006 20.2 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ44612.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXZ44612.1 - 0.0018 17.7 0.1 0.004 16.6 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ44612.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Hexapep PF00132.24 KXZ44613.1 - 0.00028 20.5 0.4 0.00052 19.6 0.4 1.5 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) CCDC66 PF15236.6 KXZ44617.1 - 0.078 12.8 2.1 0.17 11.7 2.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 CLTH PF10607.9 KXZ44620.1 - 2.1e-05 24.5 0.0 2.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain P_C PF06640.11 KXZ44620.1 - 0.11 12.7 5.1 1.3 9.2 3.8 2.2 2 0 0 2 2 2 0 P protein C-terminus LPP PF04728.13 KXZ44622.1 - 0.0013 19.1 3.5 0.19 12.1 0.0 4.2 4 0 0 4 4 4 2 Lipoprotein leucine-zipper DASH_Spc19 PF08287.11 KXZ44622.1 - 2 8.3 4.5 7.6 6.4 0.1 3.4 5 0 0 5 5 5 0 Spc19 DUF1664 PF07889.12 KXZ44623.1 - 4.8e-05 23.4 1.3 2.8 8.0 0.0 4.2 1 1 3 4 4 4 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KXZ44623.1 - 0.0052 17.1 1.5 0.61 10.4 0.1 3.5 2 2 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med21 PF11221.8 KXZ44623.1 - 0.009 16.3 7.7 0.44 10.8 1.7 2.9 1 1 1 2 2 2 2 Subunit 21 of Mediator complex Baculo_PEP_C PF04513.12 KXZ44623.1 - 0.022 14.8 2.1 0.48 10.5 0.1 3.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rab5-bind PF09311.11 KXZ44623.1 - 0.03 13.7 3.5 1.3 8.4 1.5 3.2 1 1 2 3 3 3 0 Rabaptin-like protein Atg14 PF10186.9 KXZ44623.1 - 0.052 12.6 3.7 0.79 8.8 0.0 2.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4618 PF15397.6 KXZ44623.1 - 0.065 12.7 0.3 3.5 7.0 1.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) Spc7 PF08317.11 KXZ44623.1 - 0.092 11.6 8.5 0.17 10.8 3.3 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 KXZ44623.1 - 0.11 10.0 12.9 0.37 8.2 12.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Muted PF14942.6 KXZ44623.1 - 0.11 12.8 2.4 0.24 11.7 0.5 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Hemerythrin PF01814.23 KXZ44623.1 - 0.16 12.6 0.4 0.16 12.6 0.4 3.3 2 1 2 4 4 2 0 Hemerythrin HHE cation binding domain Dynactin_p22 PF07426.11 KXZ44623.1 - 0.22 11.4 1.8 2.2 8.1 0.2 3.3 2 1 1 3 3 3 0 Dynactin subunit p22 Jnk-SapK_ap_N PF09744.9 KXZ44623.1 - 0.23 11.7 8.1 5.4 7.2 0.2 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 KXZ44623.1 - 0.27 11.3 13.4 1.3 9.2 4.1 4.7 4 1 1 5 5 5 0 TolA binding protein trimerisation Exonuc_VII_L PF02601.15 KXZ44623.1 - 0.54 9.8 9.5 0.58 9.7 7.4 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit XhlA PF10779.9 KXZ44623.1 - 0.89 9.8 8.8 4.6 7.5 0.1 4.8 4 2 2 6 6 6 0 Haemolysin XhlA BMFP PF04380.13 KXZ44623.1 - 1.5 9.3 12.9 0.93 10.0 4.0 3.8 2 1 1 3 3 3 0 Membrane fusogenic activity DUF4407 PF14362.6 KXZ44623.1 - 4.3 6.6 15.9 22 4.3 15.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 KXZ44623.1 - 6.4 6.8 6.1 13 5.8 0.4 3.5 3 1 1 4 4 4 0 Short coiled-coil protein IFT20 PF14931.6 KXZ44623.1 - 8 6.7 10.0 5.9 7.1 1.7 3.9 4 1 1 5 5 5 0 Intraflagellar transport complex B, subunit 20 MGAT2 PF05060.14 KXZ44624.1 - 0.0016 17.6 0.0 0.068 12.2 0.1 2.2 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) GNT-I PF03071.15 KXZ44624.1 - 0.035 12.9 0.1 0.087 11.6 0.0 1.6 1 1 0 1 1 1 0 GNT-I family WD-3 PF09765.9 KXZ44625.1 - 7.2e-35 120.7 0.0 1.4e-18 67.3 0.0 3.0 3 0 0 3 3 3 3 WD-repeat region FANCL_C PF11793.8 KXZ44625.1 - 7.6e-20 70.9 0.1 1.8e-19 69.7 0.1 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KXZ44625.1 - 0.0037 17.5 0.2 0.0094 16.2 0.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXZ44625.1 - 0.008 16.5 1.8 0.008 16.5 1.8 2.5 2 0 0 2 2 2 1 Ring finger domain SHIPPO-rpt PF07004.12 KXZ44626.1 - 3.1e-28 97.3 227.3 0.0022 18.8 1.5 27.2 26 0 0 26 26 26 22 Sperm-tail PG-rich repeat DUF4214 PF13946.6 KXZ44627.1 - 1.7e-05 24.8 0.1 0.071 13.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4214) GNT-I PF03071.15 KXZ44627.1 - 0.0033 16.3 0.0 0.0056 15.5 0.0 1.3 1 0 0 1 1 1 1 GNT-I family P53_TAD PF08563.11 KXZ44627.1 - 0.038 13.5 2.5 6.4 6.4 0.2 2.5 2 0 0 2 2 2 0 P53 transactivation motif Prismane PF03063.20 KXZ44628.1 - 3.4e-147 491.2 0.0 4.2e-147 490.9 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family RcsF PF16358.5 KXZ44628.1 - 0.16 12.1 0.9 0.37 10.9 0.9 1.6 1 0 0 1 1 1 0 RcsF lipoprotein BRO1 PF03097.18 KXZ44629.1 - 0.00044 19.2 0.0 0.00081 18.3 0.0 1.6 1 1 0 1 1 1 1 BRO1-like domain SAICAR_synt PF01259.18 KXZ44631.1 - 3e-73 246.5 0.0 3.9e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Ank_2 PF12796.7 KXZ44632.1 - 9.7e-06 26.1 0.0 0.046 14.3 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) FAM221 PF14753.6 KXZ44633.1 - 7e-31 107.3 13.9 9e-31 107.0 13.9 1.1 1 0 0 1 1 1 1 Protein FAM221A/B Acetone_carb_G PF08882.11 KXZ44633.1 - 0.87 9.8 2.9 19 5.4 0.0 2.8 3 0 0 3 3 3 0 Acetone carboxylase gamma subunit Ribosomal_60s PF00428.19 KXZ44633.1 - 9.5 6.9 11.5 0.31 11.6 5.4 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein CTC1_2 PF15491.6 KXZ44634.1 - 0.29 10.4 0.0 0.44 9.8 0.0 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 C2 PF00168.30 KXZ44635.1 - 2e-26 92.2 0.0 2.3e-15 56.7 0.0 3.2 3 0 0 3 3 3 3 C2 domain Peptidase_C12 PF01088.21 KXZ44636.1 - 1.5e-67 227.5 0.0 4.6e-67 225.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXZ44636.1 - 2.5e-17 62.5 0.5 5.3e-17 61.4 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases RWD PF05773.22 KXZ44637.1 - 5.9e-17 62.0 0.0 9.4e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KXZ44637.1 - 8.9e-08 32.5 8.3 3.3e-07 30.7 8.3 2.0 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 HTH_15 PF12324.8 KXZ44637.1 - 0.003 17.5 1.6 0.15 12.0 0.3 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase TFIIA PF03153.13 KXZ44637.1 - 0.75 9.7 9.3 0.85 9.5 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gaa1 PF04114.14 KXZ44638.1 - 1.9e-35 122.9 0.0 4.8e-35 121.5 0.0 1.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component PFU PF09070.11 KXZ44639.1 - 0.0045 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) UQ_con PF00179.26 KXZ44643.1 - 6.8e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PsbQ PF05757.11 KXZ44644.1 - 3 7.5 6.7 1.9 8.2 4.2 1.9 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) DHO_dh PF01180.21 KXZ44645.1 - 1.7e-92 309.8 0.0 1e-90 304.0 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KXZ44645.1 - 0.082 11.9 2.1 0.49 9.4 1.1 2.5 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Chloroa_b-bind PF00504.21 KXZ44646.1 - 0.00058 20.4 0.0 0.00094 19.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DEAD PF00270.29 KXZ44647.1 - 2.3e-40 138.3 0.4 4.1e-40 137.4 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ44647.1 - 6e-31 107.1 0.2 3.5e-30 104.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ44647.1 - 0.00062 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXZ44647.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KXZ44647.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.6 KXZ44647.1 - 0.0013 19.1 0.3 0.0092 16.3 0.2 2.2 2 1 0 2 2 2 1 AAA domain tRNA-synt_1b PF00579.25 KXZ44647.1 - 0.042 13.2 0.0 0.8 9.0 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) CMS1 PF14617.6 KXZ44647.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KXZ44647.1 - 0.12 12.7 0.4 0.35 11.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain SWI2_SNF2 PF18766.1 KXZ44647.1 - 0.29 10.7 2.4 0.44 10.2 0.2 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Oxysterol_BP PF01237.18 KXZ44648.1 - 1.3e-96 323.7 0.0 1.7e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Metallophos PF00149.28 KXZ44650.1 - 5.8e-33 115.1 0.3 7.8e-33 114.7 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXZ44650.1 - 0.0038 17.6 0.2 0.012 16.1 0.2 1.8 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain ANTAR PF03861.14 KXZ44650.1 - 0.2 11.5 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 ANTAR domain DEAD PF00270.29 KXZ44651.1 - 7.7e-32 110.5 0.0 1.2e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ44651.1 - 1.5e-23 83.3 0.0 2.9e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ44651.1 - 0.0033 17.5 0.0 0.0064 16.5 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXZ44651.1 - 0.095 13.0 0.0 2.4 8.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KXZ44651.1 - 0.11 12.9 0.1 0.44 10.9 0.1 2.0 3 0 0 3 3 3 0 AAA domain Mito_carr PF00153.27 KXZ44653.1 - 2.6e-66 219.6 3.0 2.3e-21 75.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXZ44653.1 - 0.02 14.0 0.1 0.76 8.9 0.1 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease PDZ_3 PF17815.1 KXZ44654.1 - 3.9e-39 133.8 0.0 5.7e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KXZ44654.1 - 2.5e-20 73.9 0.9 6.1e-20 72.6 0.9 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXZ44654.1 - 8.8e-10 38.8 0.0 1.4e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KXZ44654.1 - 3.6e-09 36.8 0.1 3.4e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KXZ44654.1 - 3e-05 23.8 0.3 0.038 13.8 0.1 2.8 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KXZ44654.1 - 0.0067 16.8 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KXZ44654.1 - 0.011 14.4 0.1 0.019 13.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 KXZ44654.1 - 0.038 13.8 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease tRNA-synt_1c PF00749.21 KXZ44656.1 - 1e-99 333.4 0.0 1.3e-99 333.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXZ44656.1 - 4.8e-35 121.0 0.0 4.2e-34 117.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 KXZ44656.1 - 0.00064 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXZ44656.1 - 0.0049 17.0 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ44656.1 - 0.016 15.2 0.1 0.056 13.5 0.1 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BCIP PF13862.6 KXZ44657.1 - 8.6e-46 156.3 0.0 1.5e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CysA_C_terminal PF17850.1 KXZ44657.1 - 0.63 10.7 0.0 0.63 10.7 0.0 2.0 2 0 0 2 2 2 0 CysA C-terminal regulatory domain BUD22 PF09073.10 KXZ44657.1 - 1.3 8.2 16.3 1.9 7.7 16.3 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KXZ44657.1 - 2 7.8 16.0 2.9 7.2 16.0 1.2 1 0 0 1 1 1 0 SDA1 Phytase-like PF13449.6 KXZ44658.1 - 1.4e-42 146.6 0.0 3.6e-42 145.3 0.0 1.6 1 1 0 1 1 1 1 Esterase-like activity of phytase WD40 PF00400.32 KXZ44660.1 - 4.5e-61 201.4 18.6 1.3e-11 44.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44660.1 - 4.1e-23 81.5 0.5 3.3e-05 24.1 0.0 5.5 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ44660.1 - 3.1e-11 42.8 7.0 0.0037 16.3 0.0 5.4 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXZ44660.1 - 3.4e-06 26.0 3.3 0.27 9.8 0.0 5.4 1 1 4 6 6 6 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KXZ44660.1 - 5.2e-06 26.0 0.0 0.39 10.0 0.0 3.4 2 1 1 3 3 3 2 WD40-like domain DUF5319 PF17252.2 KXZ44660.1 - 0.00046 20.4 0.0 11 6.3 0.0 4.3 2 1 3 5 5 5 2 Family of unknown function (DUF5319) Nucleoporin_N PF08801.11 KXZ44660.1 - 0.0013 17.6 1.0 1.2 7.8 0.1 4.0 1 1 1 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.6 KXZ44660.1 - 0.0083 15.5 0.2 1.3 8.3 0.0 3.1 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Peptidase_S9_N PF02897.15 KXZ44660.1 - 0.036 12.9 0.0 2 7.1 0.0 2.7 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PD40 PF07676.12 KXZ44660.1 - 0.038 13.9 0.0 20 5.3 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kelch_2 PF07646.15 KXZ44660.1 - 0.13 12.3 1.2 4.9 7.3 0.1 3.1 3 0 0 3 3 3 0 Kelch motif Nup35_RRM PF05172.13 KXZ44661.1 - 4e-16 58.8 0.0 1.5e-15 57.0 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KXZ44661.1 - 3.7e-07 30.0 0.0 5.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4072 PF13284.6 KXZ44661.1 - 0.053 14.0 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) Ge1_WD40 PF16529.5 KXZ44662.1 - 7.2e-05 21.9 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FliG_C PF01706.16 KXZ44662.1 - 0.11 12.7 9.1 0.27 11.4 9.1 1.6 1 0 0 1 1 1 0 FliG C-terminal domain WD40 PF00400.32 KXZ44662.1 - 0.41 11.6 1.4 6.9 7.7 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Phg_2220_C PF09524.10 KXZ44663.1 - 0.041 14.0 0.1 0.045 13.8 0.1 1.3 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) PFK PF00365.20 KXZ44665.1 - 1.9e-58 198.0 0.9 2.5e-58 197.7 0.9 1.1 1 0 0 1 1 1 1 Phosphofructokinase MTD PF01993.18 KXZ44665.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Glyco_hydro81C PF17652.1 KXZ44666.1 - 7.4e-211 699.6 0.0 3.4e-85 286.3 0.0 3.2 3 0 0 3 3 3 3 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KXZ44666.1 - 1.2e-59 202.1 0.1 6e-24 84.8 0.0 4.2 5 0 0 5 5 5 3 Glycosyl hydrolase family 81 N-terminal domain Phage_capsid PF05065.13 KXZ44666.1 - 0.0057 16.0 0.3 6.7 5.9 0.0 3.2 3 0 0 3 3 3 2 Phage capsid family CHRD PF07452.12 KXZ44666.1 - 0.26 12.3 0.8 62 4.6 0.0 3.5 3 0 0 3 3 3 0 CHRD domain DUF3707 PF12499.8 KXZ44670.1 - 0.00022 21.8 0.2 0.00037 21.1 0.2 1.3 1 0 0 1 1 1 1 Pherophorin Fer4_12 PF13353.6 KXZ44670.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain PAN_1 PF00024.26 KXZ44671.1 - 6.9e-22 77.2 19.9 1.9e-05 24.5 1.4 6.2 6 0 0 6 6 6 6 PAN domain PAN_4 PF14295.6 KXZ44671.1 - 7.9e-17 60.9 28.0 0.0042 17.0 0.4 7.0 6 0 0 6 6 6 6 PAN domain PAN_3 PF08277.12 KXZ44671.1 - 0.57 10.0 22.0 0.28 11.0 0.2 4.9 5 0 0 5 5 5 0 PAN-like domain DNA_pol_A_exo1 PF01612.20 KXZ44672.1 - 1.2e-13 51.1 0.0 1.2e-06 28.4 0.0 2.4 2 1 0 2 2 2 2 3'-5' exonuclease 5_3_exonuc_N PF02739.16 KXZ44673.1 - 3.6e-22 78.9 0.0 3.8e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KXZ44673.1 - 1.1e-16 61.2 0.0 2.1e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KXZ44673.1 - 0.068 13.8 0.0 0.3 11.7 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.23 KXZ44673.1 - 0.084 12.8 1.1 0.24 11.3 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif RepB PF07506.11 KXZ44673.1 - 0.13 12.3 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 RepB plasmid partitioning protein EF-hand_7 PF13499.6 KXZ44675.1 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ44675.1 - 0.087 12.8 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 EF-hand domain Kinesin PF00225.23 KXZ44676.1 - 2.3e-61 207.6 0.0 9.8e-32 110.2 0.0 2.1 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KXZ44676.1 - 9.2e-16 58.1 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding Septin PF00735.18 KXZ44677.1 - 6.6e-13 48.6 0.0 3.9e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 Septin DUF3138 PF11336.8 KXZ44677.1 - 3.6 6.1 8.0 6.4 5.3 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Septin PF00735.18 KXZ44678.1 - 6.7e-12 45.3 0.0 2.3e-10 40.2 0.0 2.7 1 1 0 1 1 1 1 Septin BAT PF15915.5 KXZ44678.1 - 0.018 14.9 1.4 0.043 13.7 1.4 1.6 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Septin PF00735.18 KXZ44679.1 - 6.9e-13 48.5 0.0 6.9e-12 45.2 0.0 2.3 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 KXZ44679.1 - 0.23 11.0 0.0 21 4.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SMC_hinge PF06470.13 KXZ44680.1 - 5.9e-22 78.2 0.2 1.7e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain MOZ_SAS PF01853.18 KXZ44682.1 - 2.2e-83 278.3 0.1 2.9e-83 277.9 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXZ44682.1 - 4.9e-21 74.1 1.1 9e-21 73.2 1.1 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KXZ44682.1 - 1.2e-15 57.1 0.1 2.2e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KXZ44682.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ44682.1 - 0.028 14.6 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family IF2_N PF04760.15 KXZ44682.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_24 PF13412.6 KXZ44682.1 - 0.081 12.5 0.2 0.25 10.9 0.2 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding tRNA-synt_1d PF00750.19 KXZ44683.1 - 2.2e-118 395.2 0.0 3.5e-118 394.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KXZ44683.1 - 1.3e-31 109.3 0.2 2.7e-31 108.2 0.2 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KXZ44683.1 - 1.1e-18 67.5 0.0 3.4e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 KXZ44683.1 - 0.023 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SAWADEE PF16719.5 KXZ44683.1 - 0.062 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 SAWADEE domain DUF2279 PF10043.9 KXZ44683.1 - 0.063 14.1 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) tRNA-synt_1 PF00133.22 KXZ44683.1 - 0.15 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) TP_methylase PF00590.20 KXZ44683.1 - 0.17 11.8 1.1 0.46 10.4 0.2 2.2 1 1 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases eIF3_subunit PF08597.10 KXZ44683.1 - 1.3 8.9 5.0 0.74 9.7 0.5 2.4 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit Bestrophin PF01062.21 KXZ44684.1 - 4.8e-19 68.8 0.2 7.2e-18 65.0 0.2 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel LptF_LptG PF03739.14 KXZ44684.1 - 0.012 14.5 0.2 0.025 13.4 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG MHYT PF03707.16 KXZ44684.1 - 0.051 13.7 1.1 0.41 10.8 0.5 2.5 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat WD40 PF00400.32 KXZ44685.1 - 9.1e-10 39.0 0.2 0.00037 21.2 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat HEPN_Toprim_N PF18871.1 KXZ44685.1 - 0.47 10.3 6.2 0.8 9.6 6.2 1.3 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Pox_A_type_inc PF04508.12 KXZ44685.1 - 1.4 8.9 7.6 7.5 6.6 0.2 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat VPS38 PF17649.1 KXZ44685.1 - 4.4 6.1 7.1 8 5.2 7.1 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DUF1499 PF07386.11 KXZ44686.1 - 4.6e-21 75.6 0.3 2e-20 73.5 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1499) ABC_tran_CTD PF16326.5 KXZ44689.1 - 0.0012 19.0 23.1 0.0019 18.4 8.0 2.6 2 1 1 3 3 3 2 ABC transporter C-terminal domain ATG16 PF08614.11 KXZ44689.1 - 0.0073 16.6 25.7 0.015 15.5 25.7 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KXZ44689.1 - 0.012 15.7 23.8 0.013 15.5 15.2 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 KXZ44689.1 - 0.022 14.3 12.9 0.029 13.9 12.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 KXZ44689.1 - 0.032 14.6 13.6 2.8 8.4 8.3 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KXZ44689.1 - 0.037 12.9 17.8 0.029 13.3 8.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KXZ44689.1 - 0.088 13.4 6.5 0.09 13.3 3.7 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4349 PF14257.6 KXZ44689.1 - 0.11 11.9 21.6 0.29 10.5 10.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF4763 PF15960.5 KXZ44689.1 - 0.21 10.8 19.0 0.053 12.8 11.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) MscS_porin PF12795.7 KXZ44689.1 - 0.49 9.9 32.6 14 5.1 32.5 2.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 KXZ44689.1 - 0.49 10.0 22.5 1.1 8.9 12.3 3.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 KXZ44689.1 - 0.56 10.6 18.7 4.8 7.6 18.7 2.3 1 1 0 1 1 1 0 Fez1 DUF16 PF01519.16 KXZ44689.1 - 0.9 10.1 7.8 5.6 7.5 5.5 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KXZ44689.1 - 1.6 9.2 4.6 5.2 7.5 0.2 3.3 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) IFT57 PF10498.9 KXZ44689.1 - 2 7.3 9.8 1.5 7.7 5.9 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 OmpH PF03938.14 KXZ44689.1 - 2.6 8.4 25.3 14 6.0 10.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PEARLI-4 PF05278.12 KXZ44689.1 - 2.6 7.5 9.6 0.22 11.1 2.4 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4407 PF14362.6 KXZ44689.1 - 3.5 6.9 17.2 6.8 5.9 17.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rotamase PF00639.21 KXZ44689.1 - 3.9 8.5 7.7 1.6 9.7 2.0 2.3 1 1 1 2 2 2 0 PPIC-type PPIASE domain DUF724 PF05266.14 KXZ44689.1 - 4.4 7.1 11.7 1 9.1 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Med9 PF07544.13 KXZ44689.1 - 4.5 7.4 12.8 2 8.6 0.3 3.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HrpB7 PF09486.10 KXZ44689.1 - 4.8 7.6 30.9 18 5.7 10.3 3.1 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) KELK PF15796.5 KXZ44689.1 - 6.2 7.3 21.7 2.2 8.8 5.3 3.0 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CorA PF01544.18 KXZ44689.1 - 6.6 6.0 9.5 5.5 6.2 5.6 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Uso1_p115_C PF04871.13 KXZ44693.1 - 0.48 10.8 16.8 1.8 9.0 16.8 2.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 KXZ44693.1 - 2.5 8.3 16.4 1.8 8.8 10.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TP53IP5 PF15331.6 KXZ44693.1 - 7.8 6.6 10.7 0.47 10.6 3.0 2.3 1 1 1 2 2 2 0 Cellular tumour antigen p53-inducible 5 Spc7 PF08317.11 KXZ44693.1 - 8 5.2 13.4 16 4.3 13.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein BTB PF00651.31 KXZ44695.1 - 7.2e-24 84.2 0.0 3.7e-23 81.9 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KXZ44695.1 - 0.028 14.5 0.3 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 BTB And C-terminal Kelch ATG16 PF08614.11 KXZ44696.1 - 0.0071 16.6 18.4 0.037 14.2 4.2 3.3 3 0 0 3 3 3 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KXZ44696.1 - 0.33 11.4 8.0 0.082 13.4 0.6 2.2 2 0 0 2 2 2 0 Fez1 SYCE1 PF15233.6 KXZ44696.1 - 0.76 9.8 5.2 0.66 10.0 3.3 1.8 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 APG6_N PF17675.1 KXZ44696.1 - 2.9 8.4 26.5 1.6 9.3 11.7 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Macoilin PF09726.9 KXZ44696.1 - 3 6.3 11.2 0.79 8.2 0.2 2.2 2 0 0 2 2 2 0 Macoilin family Rhomboid PF01694.22 KXZ44698.1 - 3.8e-26 91.9 14.4 3.8e-26 91.9 14.4 2.4 2 0 0 2 2 2 1 Rhomboid family Sporozoite_P67 PF05642.11 KXZ44698.1 - 0.058 11.5 21.8 0.55 8.3 20.3 2.2 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Methyltransf_25 PF13649.6 KXZ44700.1 - 1.4e-06 28.9 0.1 0.002 18.8 0.1 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44700.1 - 4.4e-06 27.3 0.3 0.043 14.4 0.1 3.0 3 0 0 3 3 3 2 Methyltransferase domain RPN13_C PF16550.5 KXZ44701.1 - 6.1e-23 81.1 1.4 1.1e-22 80.4 1.4 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KXZ44701.1 - 2.2e-16 60.2 0.0 3.3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor OST-HTH PF12872.7 KXZ44701.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Dynein_C PF18199.1 KXZ44702.1 - 1e-79 268.0 0.0 1.5e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 KXZ44702.1 - 1.6e-19 70.2 0.0 2.5e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KXZ44702.1 - 2.8e-05 24.0 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain ABC_tran_CTD PF16326.5 KXZ44702.1 - 0.067 13.4 1.9 0.23 11.7 1.9 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain DHR10 PF18595.1 KXZ44702.1 - 0.83 9.7 6.0 0.16 12.0 1.8 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Lipase_3 PF01764.25 KXZ44703.1 - 1.4e-11 44.4 0.0 1.4e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Zip PF02535.22 KXZ44705.1 - 5.6e-51 173.7 9.1 7.7e-51 173.3 9.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 KXZ44706.1 - 7.2e-38 130.6 10.5 1.2e-37 129.9 10.5 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 KXZ44707.1 - 7.3e-56 189.8 9.8 8.6e-56 189.6 9.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1689 PF07954.11 KXZ44707.1 - 0.028 14.8 0.0 0.08 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) PDZ PF00595.24 KXZ44708.1 - 7.7e-08 32.6 0.9 1.4e-07 31.8 0.9 1.5 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ44708.1 - 0.00036 20.8 0.5 0.00055 20.2 0.5 1.5 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KXZ44708.1 - 0.0014 18.4 0.8 0.0034 17.2 0.8 1.6 1 1 1 2 2 2 1 PDZ domain CBM_3 PF00942.18 KXZ44710.1 - 0.00024 21.5 0.0 0.00046 20.6 0.0 1.3 1 0 0 1 1 1 1 Cellulose binding domain SnoaL_2 PF12680.7 KXZ44711.1 - 2.6e-06 28.0 0.0 7.9e-06 26.5 0.0 1.8 2 1 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 KXZ44711.1 - 0.00095 19.0 0.0 0.067 13.0 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase T5orf172 PF10544.9 KXZ44712.1 - 4.1 8.0 10.0 5.9 7.5 2.1 2.3 1 1 1 2 2 2 0 T5orf172 domain AAA_7 PF12775.7 KXZ44713.1 - 2.1e-14 53.5 0.0 7.4e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 KXZ44713.1 - 6e-09 36.1 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ44713.1 - 2.5e-07 30.8 0.0 6.3e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ44713.1 - 1.6e-05 24.9 0.0 0.22 11.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXZ44713.1 - 0.013 15.7 0.5 0.061 13.6 0.2 2.3 3 0 0 3 3 3 0 AAA domain MscS_TM PF12794.7 KXZ44713.1 - 0.074 11.9 0.3 1.7 7.5 0.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 AAA_33 PF13671.6 KXZ44713.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXZ44713.1 - 0.31 10.5 0.0 0.42 10.0 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CBM_3 PF00942.18 KXZ44716.1 - 0.0023 18.3 0.0 0.0044 17.4 0.0 1.3 1 0 0 1 1 1 1 Cellulose binding domain Amino_oxidase PF01593.24 KXZ44717.1 - 5.2e-38 131.5 0.5 6.3e-38 131.2 0.5 1.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXZ44717.1 - 0.053 12.2 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KXZ44717.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M50 PF02163.22 KXZ44718.1 - 1.7e-53 181.4 0.1 2.1e-53 181.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 KXZ44718.1 - 1.2e-05 25.1 0.7 3.2e-05 23.7 0.7 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ44718.1 - 0.057 13.8 0.0 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Peptidase_M50B PF13398.6 KXZ44718.1 - 0.097 12.3 0.1 0.097 12.3 0.1 2.3 3 0 0 3 3 3 0 Peptidase M50B-like PDZ PF00595.24 KXZ44718.1 - 0.15 12.4 0.1 0.81 10.1 0.0 2.1 2 0 0 2 2 2 0 PDZ domain Sporozoite_P67 PF05642.11 KXZ44718.1 - 0.62 8.1 4.1 1.2 7.2 4.1 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GLTP PF08718.11 KXZ44720.1 - 5e-31 108.0 0.1 1.1e-30 106.9 0.1 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) TAN PF11640.8 KXZ44720.1 - 0.13 12.4 0.1 0.45 10.6 0.1 1.9 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair TF_Zn_Ribbon PF08271.12 KXZ44721.1 - 0.0023 17.4 2.0 0.0055 16.2 2.0 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2052 PF09747.9 KXZ44721.1 - 0.0051 17.0 12.2 0.0078 16.4 12.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 KXZ44721.1 - 0.0083 14.5 9.1 0.011 14.1 9.1 1.1 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.12 KXZ44721.1 - 0.0091 15.4 15.5 0.015 14.7 15.5 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 KXZ44721.1 - 0.013 15.4 5.0 0.017 14.9 5.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 KXZ44721.1 - 0.047 12.7 17.1 0.06 12.3 17.1 1.1 1 0 0 1 1 1 0 Paf1 CCDC71L PF15374.6 KXZ44721.1 - 0.11 11.7 0.6 0.15 11.3 0.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L RNA_pol_Rpc4 PF05132.14 KXZ44721.1 - 0.17 12.3 3.3 0.34 11.3 3.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 PADR1 PF08063.12 KXZ44721.1 - 0.23 11.3 3.8 0.44 10.4 3.8 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain Lar_restr_allev PF14354.6 KXZ44721.1 - 0.84 10.1 4.5 3.1 8.3 4.5 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar SDA1 PF05285.12 KXZ44721.1 - 1.6 8.1 15.7 2.2 7.6 15.7 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 KXZ44721.1 - 2.4 7.0 3.8 1.8 7.5 2.4 1.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KXZ44721.1 - 3.1 5.9 17.2 4.1 5.5 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 KXZ44721.1 - 3.9 7.8 21.9 10 6.4 21.9 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated V_ATPase_I PF01496.19 KXZ44721.1 - 5.5 4.8 5.4 6.6 4.5 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myc_N PF01056.18 KXZ44721.1 - 5.7 6.7 5.8 8.9 6.1 5.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.16 KXZ44721.1 - 7.1 5.7 7.1 10 5.2 7.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 KXZ44721.1 - 7.6 5.2 7.9 11 4.7 7.9 1.1 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.11 KXZ44721.1 - 10 5.4 17.4 17 4.6 17.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TauD PF02668.16 KXZ44722.1 - 9.1e-33 114.2 0.3 1.2e-32 113.8 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXZ44722.1 - 0.042 13.0 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 CsiD TauD PF02668.16 KXZ44723.1 - 3.6e-32 112.2 0.2 4.6e-32 111.9 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXZ44723.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 CsiD Abhydrolase_1 PF00561.20 KXZ44725.1 - 0.0047 16.6 0.4 0.012 15.2 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ank_2 PF12796.7 KXZ44726.1 - 6.4e-16 58.7 0.0 2.9e-07 31.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44726.1 - 4.8e-14 52.5 0.0 6.3e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44726.1 - 3.9e-13 48.3 0.1 0.00011 22.3 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXZ44726.1 - 2.4e-12 46.8 0.0 6.9e-07 29.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ44726.1 - 4.7e-08 33.1 0.0 0.00094 19.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat RNR_Alpha PF17975.1 KXZ44726.1 - 0.17 12.4 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain Aldedh PF00171.22 KXZ44728.1 - 2e-12 46.4 5.2 1.8e-09 36.7 3.0 2.3 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Aminotran_1_2 PF00155.21 KXZ44729.1 - 1.6e-38 132.8 0.0 1.7e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CRM1_C PF08767.11 KXZ44730.1 - 5.2e-115 384.0 0.7 5.2e-115 384.0 0.7 3.0 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KXZ44730.1 - 2.8e-40 137.8 9.4 7.7e-39 133.1 2.7 5.0 5 2 1 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KXZ44730.1 - 4.1e-33 112.8 1.4 3.8e-32 109.7 1.4 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 KXZ44730.1 - 4.9e-18 64.3 0.5 1.1e-17 63.3 0.5 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KXZ44730.1 - 2.9e-14 52.7 0.3 1e-13 51.0 0.3 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat_3 PF18787.1 KXZ44730.1 - 1.2e-07 31.7 0.9 3.6e-07 30.2 0.1 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CNOT1_TTP_bind PF16417.5 KXZ44730.1 - 0.0063 15.7 0.3 0.021 14.0 0.3 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3385 PF11865.8 KXZ44730.1 - 0.16 11.9 7.2 1 9.3 0.1 4.1 5 1 1 6 6 6 0 Domain of unknown function (DUF3385) Armet PF10208.9 KXZ44730.1 - 0.45 10.4 2.3 2.3 8.1 0.1 2.7 3 0 0 3 3 3 0 Degradation arginine-rich protein for mis-folding TRAPP PF04051.16 KXZ44731.1 - 1.1e-36 125.8 0.0 1.6e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Kelch_4 PF13418.6 KXZ44732.1 - 1.1e-43 146.9 5.0 4.3e-12 45.8 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KXZ44732.1 - 3e-34 116.7 14.5 1.2e-09 38.2 0.2 7.4 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KXZ44732.1 - 4.5e-30 103.0 7.6 1.9e-09 36.9 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KXZ44732.1 - 4.9e-25 86.9 0.1 7.2e-06 26.1 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KXZ44732.1 - 1.6e-22 79.1 7.9 5.9e-07 29.3 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KXZ44732.1 - 9.2e-22 76.1 0.4 5.2e-06 26.2 0.0 5.9 5 0 0 5 5 5 4 Kelch motif ETC_C1_NDUFA4 PF04800.12 KXZ44733.1 - 7.6e-33 112.6 0.1 1e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ank_5 PF13857.6 KXZ44734.1 - 9.2e-07 29.0 0.1 4.5e-06 26.8 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) zf-CCCH PF00642.24 KXZ44734.1 - 3.5e-05 23.6 9.7 0.0003 20.6 0.4 3.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_4 PF13637.6 KXZ44734.1 - 0.00012 22.6 0.0 0.00032 21.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf_CCCH_4 PF18345.1 KXZ44734.1 - 0.00093 19.2 0.7 0.00093 19.2 0.7 3.5 4 0 0 4 4 4 1 Zinc finger domain Ank PF00023.30 KXZ44734.1 - 0.0058 17.0 0.3 0.031 14.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXZ44734.1 - 0.0089 16.5 0.0 0.027 15.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KXZ44734.1 - 0.059 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-CCCH_2 PF14608.6 KXZ44734.1 - 0.27 11.8 20.5 0.22 12.1 3.7 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger PK PF00224.21 KXZ44735.1 - 0 1521.0 21.1 2.2e-128 428.0 1.2 4.8 5 0 0 5 5 5 4 Pyruvate kinase, barrel domain PK_C PF02887.16 KXZ44735.1 - 2.7e-49 166.3 5.6 1.4e-13 51.1 0.0 5.8 4 1 0 4 4 4 4 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXZ44735.1 - 1.8e-13 50.2 14.5 0.00024 20.3 0.8 5.2 4 0 0 4 4 4 4 HpcH/HpaI aldolase/citrate lyase family DUF4397 PF14344.6 KXZ44735.1 - 0.036 14.9 0.0 40 5.0 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4397) YDG PF18657.1 KXZ44735.1 - 0.19 12.0 5.7 16 5.8 0.2 5.1 4 0 0 4 4 4 0 YDG domain GCK PF07802.11 KXZ44736.1 - 3.2e-05 24.2 3.2 0.00012 22.4 3.2 1.8 1 1 0 1 1 1 1 GCK domain XPC-binding PF09280.11 KXZ44736.1 - 0.033 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 XPC-binding domain Malate_synthase PF01274.22 KXZ44737.1 - 6.3e-217 721.0 0.0 7.1e-217 720.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KXZ44737.1 - 0.0015 17.8 0.0 0.0048 16.1 0.0 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SKN1 PF03935.15 KXZ44738.1 - 8.4e-47 159.7 6.0 2e-33 115.6 0.6 3.4 1 1 2 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 KXZ44738.1 - 0.00014 21.4 0.0 0.00036 20.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PepSY_TM PF03929.16 KXZ44738.1 - 0.005 16.5 0.2 0.01 15.5 0.2 1.4 1 0 0 1 1 1 1 PepSY-associated TM region Tad PF13400.6 KXZ44738.1 - 0.1 12.9 0.0 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF4381 PF14316.6 KXZ44738.1 - 0.15 12.3 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TauD PF02668.16 KXZ44739.1 - 4.9e-32 111.8 0.3 6.3e-32 111.4 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXZ44739.1 - 0.049 12.7 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 CsiD Abhydrolase_1 PF00561.20 KXZ44741.1 - 0.0073 16.0 1.2 0.0083 15.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Gln-synt_C PF00120.24 KXZ44742.1 - 1.6e-79 267.4 0.0 6.6e-40 137.2 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Peptidase_M11 PF05548.11 KXZ44743.1 - 1.2e-63 215.1 3.2 1.9e-63 214.5 3.2 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 KXZ44743.1 - 0.04 12.9 0.3 0.081 11.9 0.3 1.4 1 0 0 1 1 1 0 Peptidase M66 Arm PF00514.23 KXZ44745.1 - 3.4e-06 26.9 23.9 0.0053 16.7 0.5 6.7 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat PHD PF00628.29 KXZ44747.1 - 1.4e-08 34.5 8.6 3.4e-08 33.3 8.6 1.6 1 1 0 1 1 1 1 PHD-finger TetR_C_24 PF17932.1 KXZ44747.1 - 0.13 12.5 0.3 0.13 12.5 0.3 1.9 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain rve PF00665.26 KXZ44748.1 - 2.3e-05 24.6 0.0 4.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KXZ44748.1 - 3.6e-05 23.8 0.2 6e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 KXZ44749.1 - 9e-11 41.7 0.0 2.9e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ44749.1 - 0.00052 20.3 0.0 0.0014 18.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Ammonium_transp PF00909.21 KXZ44750.1 - 1.3e-13 50.5 3.9 2.1e-13 49.7 3.9 1.3 1 0 0 1 1 1 1 Ammonium Transporter Family AAA_29 PF13555.6 KXZ44751.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXZ44751.1 - 0.019 14.6 1.1 0.033 13.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain CAP_N PF01213.19 KXZ44751.1 - 0.024 14.1 1.0 0.05 13.1 1.0 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC_tran PF00005.27 KXZ44751.1 - 0.072 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXZ44751.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ44751.1 - 0.18 11.7 0.0 5 7.0 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 KXZ44751.1 - 0.36 11.2 6.2 0.48 10.8 2.6 2.8 2 1 0 2 2 2 0 AAA ATPase domain TAF4 PF05236.14 KXZ44751.1 - 3.9 7.1 9.1 6.2 6.5 0.5 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family LapA_dom PF06305.11 KXZ44752.1 - 0.32 10.8 1.3 0.94 9.3 1.3 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KXZ44753.1 - 8.3e-24 84.4 0.0 5.5e-17 62.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44753.1 - 4.1e-20 72.2 0.0 6e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ44753.1 - 0.0027 17.6 2.0 0.006 16.5 2.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ44753.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ44753.1 - 0.091 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_9 PF00759.19 KXZ44756.1 - 1.4e-94 317.9 2.1 1.7e-94 317.6 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 WD40 PF00400.32 KXZ44757.1 - 1.3e-21 76.4 0.0 0.00017 22.3 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Elong_Iki1 PF10483.9 KXZ44758.1 - 0.00062 19.4 0.0 0.00099 18.7 0.0 1.4 2 0 0 2 2 2 1 Elongator subunit Iki1 MBOAT_2 PF13813.6 KXZ44759.1 - 2.8e-09 37.1 3.5 5.8e-09 36.1 3.5 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SAP PF02037.27 KXZ44760.1 - 0.009 15.7 0.9 0.015 15.0 0.9 1.3 1 0 0 1 1 1 1 SAP domain JUPITER PF17054.5 KXZ44760.1 - 0.017 14.6 0.2 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 Microtubule-Associated protein Jupiter DUF3552 PF12072.8 KXZ44761.1 - 6e-05 22.5 2.5 6e-05 22.5 2.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF4667 PF15700.5 KXZ44761.1 - 0.02 15.0 0.4 0.039 14.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) TMEM247 PF15444.6 KXZ44761.1 - 0.021 14.8 6.4 0.26 11.3 1.6 2.4 2 0 0 2 2 2 0 Transmembrane protein 247 Hamartin PF04388.12 KXZ44761.1 - 0.08 11.6 6.8 0.014 14.2 2.6 1.7 2 0 0 2 2 2 0 Hamartin protein Allexi_40kDa PF05549.11 KXZ44761.1 - 0.86 9.1 4.6 1.7 8.1 4.6 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4637 PF15470.6 KXZ44761.1 - 4.7 6.9 7.6 0.36 10.5 2.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) ABC_membrane PF00664.23 KXZ44762.1 - 4.3e-43 147.9 28.5 3e-22 79.6 14.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ44762.1 - 2.7e-37 128.3 0.0 3.2e-18 66.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXZ44762.1 - 5.8e-09 35.7 1.4 0.0013 18.2 0.0 3.2 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXZ44762.1 - 0.0027 17.8 0.3 0.01 15.9 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KXZ44762.1 - 0.0033 17.1 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXZ44762.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 KXZ44762.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXZ44762.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain zf_CCCH_4 PF18345.1 KXZ44763.1 - 1.5e-13 50.3 20.8 1e-06 28.6 3.9 3.3 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KXZ44763.1 - 1.5e-10 40.7 12.8 0.00022 21.0 0.9 3.2 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXZ44763.1 - 3.1e-06 26.9 16.4 7.5e-06 25.6 2.8 2.7 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXZ44763.1 - 9.8e-05 22.5 5.1 0.00048 20.3 5.2 1.9 1 1 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 KXZ44763.1 - 0.00065 20.4 8.3 1.6 9.4 0.7 3.3 1 1 2 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 KXZ44763.1 - 0.00073 19.9 14.5 0.1 13.1 0.6 3.2 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger MdcG PF10620.9 KXZ44763.1 - 0.011 15.5 2.9 0.011 15.5 2.9 2.5 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG Aminotran_1_2 PF00155.21 KXZ44764.1 - 1.7e-86 290.7 0.0 1.9e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ABC_tran PF00005.27 KXZ44765.1 - 3.3e-55 186.4 0.0 1.7e-25 90.1 0.0 3.6 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 KXZ44765.1 - 1.5e-42 146.1 28.1 8.8e-22 78.0 13.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXZ44765.1 - 4.9e-14 52.3 7.2 0.0013 18.2 0.0 5.0 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ44765.1 - 4.4e-06 26.4 0.1 0.0095 15.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXZ44765.1 - 2.1e-05 24.6 1.0 0.012 15.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXZ44765.1 - 0.0007 19.7 0.1 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 KXZ44765.1 - 0.0014 18.5 0.0 1.9 8.2 0.0 3.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXZ44765.1 - 0.0039 17.4 0.1 6.6 7.0 0.0 3.2 3 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KXZ44765.1 - 0.0042 16.5 1.0 0.79 9.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family SbcCD_C PF13558.6 KXZ44765.1 - 0.0071 16.6 0.0 54 4.1 0.0 3.8 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KXZ44765.1 - 0.0075 16.2 0.1 0.085 12.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXZ44765.1 - 0.029 14.8 0.2 0.46 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KXZ44765.1 - 0.033 14.7 0.0 3.1 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXZ44765.1 - 0.034 14.3 2.3 4 7.5 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KXZ44765.1 - 0.036 13.8 1.2 5.9 6.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXZ44765.1 - 0.042 14.1 0.2 0.6 10.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXZ44765.1 - 0.079 12.3 0.6 3.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AIG1 family MeaB PF03308.16 KXZ44765.1 - 0.12 11.3 1.3 4.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Vg_Tdu PF07545.14 KXZ44765.1 - 0.17 11.7 0.1 40 4.1 0.0 2.9 2 0 0 2 2 2 0 Vestigial/Tondu family Zeta_toxin PF06414.12 KXZ44765.1 - 1.7 7.9 3.6 8.6 5.6 0.1 2.8 4 0 0 4 4 4 0 Zeta toxin DUF4538 PF15061.6 KXZ44766.1 - 0.014 15.2 0.1 0.035 13.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Xpo1 PF08389.12 KXZ44767.1 - 2.7e-10 40.5 0.0 6.9e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 KXZ44767.1 - 1.3e-09 37.8 0.1 3.1e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep PF18773.1 KXZ44767.1 - 9.2e-05 22.1 0.1 0.00019 21.1 0.1 1.4 1 0 0 1 1 1 1 Importin 13 repeat MAP65_ASE1 PF03999.12 KXZ44768.1 - 0.018 13.8 0.4 0.023 13.4 0.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) eIF-5a PF01287.20 KXZ44769.1 - 2e-20 72.6 0.6 3e-20 72.1 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KXZ44769.1 - 0.028 14.5 0.1 0.048 13.7 0.1 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain FolB PF02152.18 KXZ44770.1 - 9.2e-27 93.8 0.0 1e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase Pkinase_Tyr PF07714.17 KXZ44771.1 - 7.6e-33 113.9 0.0 4.7e-16 58.9 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ44771.1 - 1.5e-19 70.4 0.1 6.3e-09 35.6 0.0 3.3 2 2 1 3 3 3 2 Protein kinase domain DUF4448 PF14610.6 KXZ44771.1 - 0.019 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ribosomal_60s PF00428.19 KXZ44771.1 - 7.7 7.2 10.6 0.85 10.2 3.8 3.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein Guanylate_cyc PF00211.20 KXZ44772.1 - 4.1e-53 179.7 0.0 7.2e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SRC-1 PF08832.10 KXZ44772.1 - 0.11 13.6 0.9 0.49 11.5 0.0 2.3 2 0 0 2 2 2 0 Steroid receptor coactivator Transcrip_reg PF01709.20 KXZ44773.1 - 1.1e-67 228.0 0.1 1.2e-67 227.8 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator ADH_zinc_N PF00107.26 KXZ44773.1 - 0.01 15.8 1.8 0.049 13.6 0.2 2.2 1 1 0 2 2 2 0 Zinc-binding dehydrogenase LPD22 PF18834.1 KXZ44773.1 - 0.013 15.7 0.1 0.033 14.4 0.1 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 Flagellar_put PF12611.8 KXZ44773.1 - 0.099 12.4 0.4 0.2 11.4 0.4 1.5 1 0 0 1 1 1 0 Putative flagellar Methyltransf_21 PF05050.12 KXZ44774.1 - 4.1e-13 49.7 0.0 6.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 KXZ44774.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein RPN6_N PF18055.1 KXZ44775.1 - 2.2e-36 124.8 0.2 7.4e-36 123.1 0.2 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KXZ44775.1 - 2e-17 63.6 0.0 1.2e-16 61.1 0.0 2.3 3 1 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 KXZ44775.1 - 6.1e-09 35.5 0.4 9.8e-08 31.6 0.0 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain RPN7 PF10602.9 KXZ44775.1 - 0.047 13.4 0.1 0.21 11.3 0.1 2.2 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 KXZ44775.1 - 0.075 12.7 0.3 0.075 12.7 0.3 2.2 2 2 0 2 2 2 0 Tetratricopeptide repeat-like domain Guanylate_cyc PF00211.20 KXZ44776.1 - 2.6e-53 180.3 0.0 4.2e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ44778.1 - 1.9e-52 177.6 0.0 2.7e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PI3_PI4_kinase PF00454.27 KXZ44780.1 - 1.8e-37 129.5 0.0 8.5e-37 127.3 0.0 2.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase V-SNARE_C PF12352.8 KXZ44782.1 - 5.4e-07 29.8 4.3 0.0003 21.0 0.3 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 KXZ44782.1 - 1.2e-05 25.3 3.2 0.0021 18.0 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) Sec20 PF03908.13 KXZ44782.1 - 0.031 14.2 1.8 0.036 14.0 0.6 1.7 2 0 0 2 2 2 0 Sec20 DUF4558 PF15104.6 KXZ44782.1 - 0.078 13.0 6.7 0.094 12.8 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) Laminin_II PF06009.12 KXZ44782.1 - 0.083 12.9 9.3 1.5 8.8 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II KxDL PF10241.9 KXZ44782.1 - 0.18 12.1 3.1 0.85 9.9 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein SNARE PF05739.19 KXZ44782.1 - 0.2 11.7 0.2 0.2 11.7 0.2 2.3 3 0 0 3 3 3 0 SNARE domain SlyX PF04102.12 KXZ44782.1 - 1.7 9.3 10.6 34 5.1 0.0 4.0 2 2 2 4 4 4 0 SlyX NPV_P10 PF05531.12 KXZ44782.1 - 2.5 8.6 7.8 2.8 8.5 2.8 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CYSTM PF12734.7 KXZ44782.1 - 6.4 7.2 11.5 23 5.4 11.5 2.0 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance BTB PF00651.31 KXZ44784.1 - 9.8e-14 51.5 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain tRNA_anti-codon PF01336.25 KXZ44786.1 - 5.8e-09 35.8 0.5 8.7e-09 35.2 0.5 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 KXZ44786.1 - 2.2e-06 28.3 0.0 5.1e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti_2 PF13742.6 KXZ44786.1 - 6.9e-05 23.0 0.3 0.00018 21.6 0.2 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KXZ44786.1 - 0.00029 20.7 0.2 0.0004 20.2 0.2 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Ten1_2 PF15490.6 KXZ44786.1 - 0.026 14.2 0.3 0.082 12.6 0.3 1.8 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit Dickkopf_N PF04706.12 KXZ44787.1 - 0.00012 22.5 41.2 0.00015 22.1 14.2 3.6 2 1 1 3 3 3 3 Dickkopf N-terminal cysteine-rich region EB PF01683.18 KXZ44787.1 - 0.0043 17.3 5.4 0.0043 17.3 5.4 3.9 2 2 1 3 3 3 1 EB module Nucleotid_trans PF03407.16 KXZ44788.1 - 4.5e-19 69.3 1.0 7e-19 68.6 1.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 KXZ44789.1 - 2.4e-26 93.0 1.1 4e-26 92.3 1.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase E1_dh PF00676.20 KXZ44790.1 - 5e-78 262.1 0.0 6.6e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KXZ44790.1 - 3.3e-08 33.5 0.0 7.8e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KXZ44790.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain PLAC8 PF04749.17 KXZ44792.1 - 5e-10 40.3 1.7 7.2e-10 39.8 1.7 1.2 1 0 0 1 1 1 1 PLAC8 family Pkinase_Tyr PF07714.17 KXZ44793.1 - 1.8e-29 102.9 0.0 9.1e-26 90.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ44793.1 - 5.5e-28 98.1 0.0 9.3e-24 84.2 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ44793.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SAND PF01342.21 KXZ44794.1 - 1.4e-12 47.1 0.0 2.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 SAND domain Ish1 PF10281.9 KXZ44794.1 - 0.19 12.1 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Pyr_redox_2 PF07992.14 KXZ44795.1 - 3.2e-29 102.1 0.0 1.7e-28 99.7 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ44795.1 - 6.2e-13 49.1 0.0 3e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ44795.1 - 1.8e-11 43.8 0.0 3.1e-07 30.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXZ44795.1 - 0.088 13.3 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Ran_BP1 PF00638.18 KXZ44796.1 - 3.9e-13 49.7 0.0 6.5e-12 45.8 0.0 2.4 3 0 0 3 3 3 1 RanBP1 domain Ank_2 PF12796.7 KXZ44797.1 - 3.2e-25 88.5 0.1 2.9e-11 43.8 0.0 4.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44797.1 - 1.7e-23 81.9 3.5 0.00012 22.3 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KXZ44797.1 - 3.4e-23 81.4 3.9 1.3e-11 44.5 0.2 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ44797.1 - 1.4e-21 76.6 2.3 4.2e-10 40.0 0.6 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44797.1 - 5.5e-17 60.1 2.8 0.011 16.2 0.0 6.0 5 1 0 5 5 5 5 Ankyrin repeat Cytomega_UL20A PF05984.12 KXZ44797.1 - 0.14 12.5 1.2 0.37 11.1 1.2 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Mito_carr PF00153.27 KXZ44799.1 - 2.6e-56 187.5 4.4 1.1e-19 70.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 KXZ44800.1 - 2.1e-11 43.7 14.1 2.5e-11 43.5 14.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXZ44800.1 - 1.1e-05 24.8 14.3 1.4e-05 24.5 14.3 1.1 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KXZ44800.1 - 0.00066 19.0 5.1 0.00066 19.0 5.1 2.3 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport Wzy_C PF04932.15 KXZ44800.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.8 2 1 0 2 2 2 0 O-Antigen ligase DUF2613 PF11021.8 KXZ44800.1 - 0.21 11.7 0.2 0.21 11.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) EamA PF00892.20 KXZ44800.1 - 0.75 10.0 26.3 0.16 12.2 12.8 2.8 1 1 2 3 3 3 0 EamA-like transporter family DUF3084 PF11283.8 KXZ44800.1 - 0.97 9.5 6.6 0.24 11.4 0.5 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3084) DUF3915 PF13054.6 KXZ44800.1 - 1.7 8.6 6.0 0.54 10.3 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) TrbC PF04956.13 KXZ44800.1 - 1.8 8.9 11.5 3 8.1 1.4 2.8 2 1 0 2 2 2 0 TrbC/VIRB2 family TauD PF02668.16 KXZ44802.1 - 3e-23 83.0 1.7 1.6e-19 70.7 0.6 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXZ44802.1 - 0.0009 18.4 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 CsiD TilS PF09179.11 KXZ44802.1 - 0.28 11.7 0.3 0.28 11.7 0.3 3.4 5 0 0 5 5 5 0 TilS substrate binding domain AAA_12 PF13087.6 KXZ44803.1 - 3e-25 89.0 0.0 3.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXZ44803.1 - 0.052 13.4 0.4 5.3 7.0 0.3 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain NosD PF05048.13 KXZ44803.1 - 3.8 6.7 6.7 5.3 6.2 6.7 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF2237 PF09996.9 KXZ44805.1 - 4e-53 178.3 0.1 5.2e-53 177.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) GCK PF07802.11 KXZ44806.1 - 1.7e-09 37.9 1.6 1.7e-09 37.9 1.6 1.6 1 1 1 2 2 2 1 GCK domain CHCH PF06747.13 KXZ44806.1 - 0.0017 18.4 0.7 0.061 13.5 0.3 2.3 2 0 0 2 2 2 1 CHCH domain zf-CHY PF05495.12 KXZ44807.1 - 1.3e-13 51.2 5.6 1.3e-13 51.2 5.6 3.2 2 1 1 3 3 3 1 CHY zinc finger A2L_zn_ribbon PF08792.10 KXZ44807.1 - 2 8.2 5.8 28 4.6 0.2 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain Ras PF00071.22 KXZ44808.1 - 1e-33 116.2 0.0 1.2e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ44808.1 - 3e-12 46.8 0.0 4.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KXZ44808.1 - 0.00024 20.7 0.0 0.0003 20.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KXZ44808.1 - 0.0019 17.7 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXZ44808.1 - 0.057 13.3 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Ras PF00071.22 KXZ44809.1 - 1.4e-60 203.6 0.0 1.8e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ44809.1 - 3.3e-31 108.0 0.0 5.1e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ44809.1 - 1e-13 51.1 0.1 1.7e-13 50.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXZ44809.1 - 0.00014 21.5 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXZ44809.1 - 0.0028 17.7 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXZ44809.1 - 0.0068 15.8 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF4349 PF14257.6 KXZ44810.1 - 0.079 12.4 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Methyltransf_23 PF13489.6 KXZ44811.1 - 2.3e-16 60.1 0.0 2.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44811.1 - 3.6e-15 56.4 0.0 1e-14 54.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ44811.1 - 1.6e-14 54.4 0.0 1.7e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ44811.1 - 6.8e-14 51.8 0.0 1.6e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXZ44811.1 - 7.2e-10 38.8 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ44811.1 - 2.5e-08 34.6 0.0 4.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_bind_3 PF17176.4 KXZ44812.1 - 0.052 13.8 0.8 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 tRNA-binding domain ABC_tran PF00005.27 KXZ44813.1 - 8.2e-14 52.3 0.0 1e-13 52.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.6 KXZ44813.1 - 0.0009 19.7 0.0 0.0011 19.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXZ44813.1 - 0.0072 16.3 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KXZ44813.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXZ44813.1 - 0.013 15.2 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ44813.1 - 0.014 15.8 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXZ44813.1 - 0.043 14.4 0.0 0.048 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ44813.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXZ44813.1 - 0.1 13.0 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.7 KXZ44815.1 - 7e-60 199.6 14.7 9.7e-19 67.8 1.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44815.1 - 1.1e-44 145.2 1.4 9.4e-08 31.8 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KXZ44815.1 - 6.1e-44 146.6 4.7 1.3e-07 31.8 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KXZ44815.1 - 5.6e-39 132.0 3.0 2.8e-10 40.5 0.1 4.3 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ44815.1 - 4.6e-34 116.0 18.5 5.7e-09 36.1 0.1 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Calponin PF00402.18 KXZ44815.1 - 0.00021 20.9 7.9 31 4.3 0.0 6.0 6 0 0 6 6 6 0 Calponin family repeat B12-binding_2 PF02607.17 KXZ44815.1 - 0.008 16.6 7.6 18 5.9 0.0 4.7 4 1 0 4 4 4 1 B12 binding domain GDP_Man_Dehyd PF16363.5 KXZ44815.1 - 0.25 10.7 1.8 0.44 9.9 0.6 2.1 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase HTH_16 PF12645.7 KXZ44815.1 - 1.4 9.0 6.3 97 3.1 0.0 4.4 5 0 0 5 5 5 0 Helix-turn-helix domain TRP PF06011.12 KXZ44816.1 - 3.4 6.3 14.4 10 4.7 14.3 1.8 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel TRP PF06011.12 KXZ44817.1 - 4.2e-07 29.0 7.5 9e-07 28.0 7.5 1.5 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel NosD PF05048.13 KXZ44817.1 - 0.0064 15.8 6.6 0.016 14.5 4.0 2.2 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) JAMP PF05571.12 KXZ44817.1 - 0.098 12.3 0.1 0.098 12.3 0.1 1.8 2 0 0 2 2 2 0 JNK1/MAPK8-associated membrane protein Chlam_PMP PF02415.17 KXZ44817.1 - 2.1 9.0 0.0 0.78 10.3 2.0 14.1 14 1 0 14 14 14 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat PBP1_TM PF14812.6 KXZ44819.1 - 0.015 15.7 7.6 0.017 15.5 7.6 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TLP-20 PF06088.11 KXZ44819.1 - 7.8 6.4 7.4 8.9 6.2 7.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Chlam_PMP PF02415.17 KXZ44820.1 - 3.6e-12 46.0 93.2 0.02 15.3 0.1 13.2 13 1 0 13 13 13 9 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 KXZ44820.1 - 0.00024 21.0 36.9 0.17 11.7 36.9 3.2 1 1 0 1 1 1 1 Right handed beta helix region Phosphonate-bd PF12974.7 KXZ44822.1 - 0.26 10.9 2.9 0.33 10.5 2.9 1.1 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Roc PF08477.13 KXZ44824.1 - 6.2e-23 81.3 0.0 1e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KXZ44824.1 - 8.7e-17 61.6 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 KXZ44824.1 - 6.6e-13 48.6 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 KXZ44824.1 - 1.3e-10 41.7 0.1 2.2e-08 34.6 0.0 3.5 4 0 0 4 4 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ44824.1 - 1.7e-09 37.8 0.0 7.8e-06 26.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ44824.1 - 3e-09 37.2 0.0 3.8e-06 27.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44824.1 - 1.6e-07 31.1 0.0 0.0095 16.4 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KXZ44824.1 - 8.1e-07 29.2 0.1 0.00016 21.9 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Arf PF00025.21 KXZ44824.1 - 2.6e-06 27.0 0.0 5.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXZ44824.1 - 0.0023 17.4 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXZ44824.1 - 0.028 14.5 0.0 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF937 PF06078.11 KXZ44824.1 - 0.11 13.1 1.4 7.3 7.2 0.1 3.7 4 1 0 4 4 3 0 Bacterial protein of unknown function (DUF937) Gtr1_RagA PF04670.12 KXZ44824.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TsaE PF02367.17 KXZ44824.1 - 0.17 11.9 0.5 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KXZ44824.1 - 0.17 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Pkinase PF00069.25 KXZ44825.1 - 1.4e-55 188.5 0.0 1.9e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44825.1 - 3.4e-23 82.3 0.0 4.4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ44825.1 - 0.0087 14.9 0.0 0.15 10.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Ank_5 PF13857.6 KXZ44826.1 - 5.4e-10 39.3 0.0 4.4e-05 23.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44826.1 - 4.7e-09 35.8 0.0 0.0076 16.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXZ44826.1 - 1.2e-07 32.2 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ44826.1 - 2e-07 31.2 0.0 0.0089 16.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXZ44826.1 - 1.5e-05 25.5 0.0 0.0001 22.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_9 PF12781.7 KXZ44826.1 - 0.0014 17.8 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region Sporozoite_P67 PF05642.11 KXZ44826.1 - 0.14 10.3 1.3 0.18 9.8 1.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen cNMP_binding PF00027.29 KXZ44827.1 - 1.4e-16 60.3 1.0 0.00023 21.2 0.0 4.7 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain TFIIA PF03153.13 KXZ44827.1 - 8.6 6.2 9.0 14 5.6 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med21 PF11221.8 KXZ44828.1 - 9.8e-12 45.3 1.1 1.1e-11 45.2 1.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 KXZ44828.1 - 8.8e-06 25.7 0.6 1.4e-05 25.1 0.3 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Spectrin PF00435.21 KXZ44828.1 - 0.002 18.6 0.9 0.0023 18.4 0.9 1.0 1 0 0 1 1 1 1 Spectrin repeat Calici_MSP PF05752.11 KXZ44828.1 - 0.043 13.6 0.1 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 Calicivirus minor structural protein FTA4 PF13093.6 KXZ44828.1 - 0.05 13.5 0.4 0.052 13.4 0.4 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4439 PF14530.6 KXZ44828.1 - 0.056 14.1 0.2 0.068 13.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) MCU PF04678.13 KXZ44828.1 - 0.21 11.7 0.2 0.21 11.7 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Choline_transpo PF04515.12 KXZ44830.1 - 1.4e-45 155.9 11.1 2.5e-45 155.1 11.1 1.4 1 0 0 1 1 1 1 Plasma-membrane choline transporter HTH_29 PF13551.6 KXZ44830.1 - 0.092 12.8 0.1 2.2 8.3 0.0 2.9 2 0 0 2 2 2 0 Winged helix-turn helix tRNA_m1G_MT PF01746.21 KXZ44831.1 - 3.9e-24 85.4 0.0 5.2e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase BCDHK_Adom3 PF10436.9 KXZ44832.1 - 3.6e-46 157.0 0.0 6.2e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXZ44832.1 - 1.6e-12 48.0 0.0 2.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXZ44832.1 - 0.00071 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SesA PF17107.5 KXZ44832.1 - 0.029 14.6 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2423 PF10338.9 KXZ44833.1 - 0.009 16.2 5.6 0.029 14.6 5.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2423) PDH PF02153.17 KXZ44834.1 - 3.3e-18 65.6 0.0 4.3e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KXZ44834.1 - 2.3e-11 44.1 0.0 5.4e-11 42.9 0.0 1.6 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXZ44834.1 - 1.1e-08 34.7 0.0 1.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXZ44834.1 - 3.8e-07 30.4 0.0 6.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 KXZ44834.1 - 0.0023 17.8 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain Shikimate_DH PF01488.20 KXZ44834.1 - 0.0049 16.9 0.0 0.01 15.9 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KXZ44834.1 - 0.0066 16.1 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXZ44834.1 - 0.024 14.5 0.0 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXZ44834.1 - 0.026 15.3 0.1 0.063 14.1 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.23 KXZ44834.1 - 0.05 13.6 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KXZ44834.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 KXZ44834.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CDC50 PF03381.15 KXZ44835.1 - 4.3e-82 275.8 0.0 4.8e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family HAUS4 PF14735.6 KXZ44836.1 - 6e-16 58.9 4.6 7.2e-16 58.6 4.6 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 GSH_synth_ATP PF03917.17 KXZ44836.1 - 0.00051 18.9 2.2 0.00061 18.7 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain Cnn_1N PF07989.11 KXZ44836.1 - 0.016 15.4 0.4 0.016 15.4 0.4 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KXZ44836.1 - 0.029 14.1 1.5 5.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF5315 PF17242.2 KXZ44836.1 - 0.13 12.1 1.3 0.25 11.2 1.3 1.5 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) CCT PF06203.14 KXZ44837.1 - 3.9e-17 62.0 8.1 6.4e-17 61.3 8.1 1.4 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 KXZ44837.1 - 0.2 11.6 2.1 0.4 10.6 2.1 1.6 1 0 0 1 1 1 0 Divergent CCT motif Asn_synthase PF00733.21 KXZ44838.1 - 5e-99 332.3 0.6 8.6e-58 196.7 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXZ44838.1 - 2e-38 131.0 0.0 3.2e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXZ44838.1 - 4.9e-27 94.8 0.0 9.7e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXZ44838.1 - 1.7e-11 44.0 0.0 3.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXZ44838.1 - 0.0018 17.5 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD synthase Mito_carr PF00153.27 KXZ44839.1 - 3.1e-58 193.7 0.0 2e-19 69.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.12 KXZ44840.1 - 1.5e-22 79.5 3.0 2.8e-22 78.7 3.0 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mnd1 PF03962.15 KXZ44841.1 - 5.6e-25 87.4 0.2 9.4e-25 86.7 0.2 1.4 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KXZ44841.1 - 4.3e-13 49.1 0.0 9.3e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Leucine zipper with capping helix domain RILP PF11461.8 KXZ44841.1 - 0.0037 17.5 0.5 0.042 14.1 0.0 2.4 2 0 0 2 2 2 1 Rab interacting lysosomal protein Seryl_tRNA_N PF02403.22 KXZ44841.1 - 0.021 15.1 2.6 0.045 14.0 2.6 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Penicillinase_R PF03965.16 KXZ44841.1 - 0.024 15.0 0.1 0.23 11.8 0.1 2.2 1 1 1 2 2 2 0 Penicillinase repressor Swi5 PF07061.11 KXZ44841.1 - 0.039 14.0 1.0 0.077 13.1 1.0 1.5 1 0 0 1 1 1 0 Swi5 TrmB PF01978.19 KXZ44841.1 - 0.057 13.3 0.2 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HU-CCDC81_bac_2 PF18175.1 KXZ44841.1 - 0.16 11.9 0.4 15 5.6 0.1 2.4 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 APG6_N PF17675.1 KXZ44841.1 - 0.55 10.8 5.0 0.9 10.1 5.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Nup88 PF10168.9 KXZ44842.1 - 1.4e-09 36.4 0.0 2.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore component ATG16 PF08614.11 KXZ44842.1 - 0.27 11.4 3.8 8.4 6.6 0.1 2.7 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Spore_YtfJ PF09579.10 KXZ44842.1 - 8.2 6.7 8.8 21 5.4 0.8 3.5 3 0 0 3 3 3 0 Sporulation protein YtfJ (Spore_YtfJ) Proteasome PF00227.26 KXZ44844.1 - 1.9e-44 151.5 1.1 2.1e-44 151.3 1.1 1.0 1 0 0 1 1 1 1 Proteasome subunit YqgF PF14639.6 KXZ44844.1 - 0.09 12.5 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Dpy-30 PF05186.13 KXZ44845.1 - 1.1e-16 60.2 0.3 2e-16 59.4 0.3 1.4 1 0 0 1 1 1 1 Dpy-30 motif SOTI PF17079.5 KXZ44845.1 - 0.048 14.1 0.1 0.059 13.8 0.1 1.3 1 0 0 1 1 1 0 Male-specific protein scotti DUF3597 PF12200.8 KXZ44845.1 - 9.9 6.7 8.7 0.98 10.0 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) tRNA-synt_2 PF00152.20 KXZ44846.1 - 2.6e-73 246.9 0.0 3.3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXZ44846.1 - 6.4e-12 45.3 0.3 2e-11 43.7 0.6 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXZ44846.1 - 0.00084 18.9 0.7 0.37 10.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) SNAPc_SNAP43 PF09808.9 KXZ44847.1 - 0.00033 20.6 0.0 0.00047 20.1 0.0 1.1 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Mago-bind PF09282.10 KXZ44848.1 - 1.8e-14 53.3 3.6 2.8e-14 52.7 3.6 1.3 1 0 0 1 1 1 1 Mago binding ATG16 PF08614.11 KXZ44848.1 - 1.1 9.4 8.9 2.5 8.3 8.9 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FlxA PF14282.6 KXZ44848.1 - 1.6 8.8 13.8 0.34 10.9 5.2 2.5 2 1 0 2 2 2 0 FlxA-like protein DUF1178 PF06676.11 KXZ44848.1 - 3.8 7.9 8.6 6.2 7.2 8.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) PAN_4 PF14295.6 KXZ44850.1 - 0.024 14.5 0.6 0.024 14.5 0.6 2.0 2 0 0 2 2 2 0 PAN domain DUF4407 PF14362.6 KXZ44850.1 - 0.078 12.3 8.5 0.12 11.7 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cystatin PF00031.21 KXZ44850.1 - 0.11 12.7 0.0 19 5.6 0.0 2.5 2 0 0 2 2 2 0 Cystatin domain PYC_OADA PF02436.18 KXZ44850.1 - 0.14 11.9 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain IHABP4_N PF16174.5 KXZ44850.1 - 0.88 10.2 13.7 1.9 9.1 13.7 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4710 PF15828.5 KXZ44850.1 - 2 8.6 5.3 4.6 7.4 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) SRP-alpha_N PF04086.13 KXZ44850.1 - 2.1 8.2 8.4 2.9 7.7 8.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TAF4 PF05236.14 KXZ44850.1 - 2.4 7.8 14.4 4.1 7.1 14.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Rtf2 PF04641.12 KXZ44850.1 - 6.3 6.1 10.5 9.7 5.5 10.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DnaJ_CXXCXGXG PF00684.19 KXZ44851.1 - 0.0057 17.0 13.1 0.68 10.3 7.5 3.0 1 1 1 2 2 2 2 DnaJ central domain Hint PF01079.20 KXZ44853.1 - 5.3e-25 88.2 0.0 8.3e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.11 KXZ44853.1 - 0.034 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Pretoxin HINT domain Amidohydro_3 PF07969.11 KXZ44855.1 - 2.8e-12 46.9 0.6 3.9e-12 46.4 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family WD40 PF00400.32 KXZ44857.1 - 5.1e-33 112.6 20.2 3.2e-05 24.6 0.7 9.8 10 0 0 10 10 10 8 WD domain, G-beta repeat PQQ_2 PF13360.6 KXZ44857.1 - 6.4e-05 22.7 1.2 0.0032 17.1 0.0 3.3 4 0 0 4 4 4 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KXZ44857.1 - 0.00023 21.4 0.1 11 6.4 0.0 5.4 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KXZ44857.1 - 0.016 15.1 0.2 0.34 10.9 0.1 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat Nup160 PF11715.8 KXZ44857.1 - 0.043 12.5 2.1 9.5 4.7 0.0 3.6 3 1 1 4 4 4 0 Nucleoporin Nup120/160 HECT PF00632.25 KXZ44858.1 - 3.4e-87 292.8 0.0 4.8e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Recep_L_domain PF01030.24 KXZ44859.1 - 2.2e-11 43.8 0.0 2 8.6 0.0 7.2 2 2 4 7 7 7 6 Receptor L domain Elongin_A PF06881.11 KXZ44861.1 - 0.0036 17.8 0.8 0.0047 17.4 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Nucleocapsid-N PF11030.8 KXZ44861.1 - 0.2 11.6 3.1 0.36 10.8 1.9 2.0 2 0 0 2 2 2 0 Nucleocapsid protein N Cytochrom_B561 PF03188.16 KXZ44862.1 - 1.8e-17 63.7 1.8 2.9e-17 63.1 1.8 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PsbP PF01789.16 KXZ44862.1 - 4.9e-13 49.5 0.0 8.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 PsbP XRN_M PF17846.1 KXZ44863.1 - 7.8e-106 354.7 0.0 1.2e-105 354.0 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KXZ44863.1 - 4.9e-96 320.8 0.0 7.1e-96 320.3 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KXZ44863.1 - 1.1e-30 106.8 0.1 2.7e-30 105.6 0.0 1.6 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 KXZ44863.1 - 9.4e-17 60.9 0.1 1.8e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 KXZ44863.1 - 0.00076 19.7 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 2 Exoribonuclease Xrn1 D2/D3 domain DUF3261 PF11659.8 KXZ44863.1 - 0.049 13.5 0.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3261) baeRF_family10 PF18854.1 KXZ44865.1 - 0.0029 17.9 1.4 0.0032 17.7 1.4 1.1 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 GrpE PF01025.19 KXZ44865.1 - 0.0047 16.6 4.8 0.0051 16.5 4.8 1.1 1 0 0 1 1 1 1 GrpE MIP-T3_C PF17749.1 KXZ44865.1 - 0.005 16.8 7.0 0.0056 16.7 7.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region OmpH PF03938.14 KXZ44865.1 - 0.012 16.0 11.0 0.012 16.0 11.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DLP_helical PF18709.1 KXZ44865.1 - 0.013 14.7 3.5 0.014 14.6 3.5 1.0 1 0 0 1 1 1 0 Dynamin-like helical domain CRIC_ras_sig PF10534.9 KXZ44865.1 - 0.031 14.4 1.5 0.038 14.1 1.5 1.2 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras PocR PF10114.9 KXZ44865.1 - 0.04 13.7 2.0 0.048 13.4 2.0 1.0 1 0 0 1 1 1 0 Sensory domain found in PocR Het-C PF07217.11 KXZ44865.1 - 0.041 12.4 1.6 0.038 12.5 1.6 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C USP8_interact PF08941.10 KXZ44865.1 - 0.065 13.0 3.7 0.067 13.0 3.7 1.1 1 0 0 1 1 1 0 USP8 interacting DUF4407 PF14362.6 KXZ44865.1 - 0.081 12.3 4.2 0.091 12.1 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRP36 PF06102.12 KXZ44865.1 - 0.089 12.8 8.5 0.1 12.6 8.5 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Dynein_light PF01221.18 KXZ44865.1 - 0.093 13.1 2.3 0.12 12.7 2.3 1.3 1 0 0 1 1 1 0 Dynein light chain type 1 CobU PF02283.16 KXZ44865.1 - 0.094 12.3 0.9 0.094 12.3 0.9 1.1 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF1664 PF07889.12 KXZ44865.1 - 0.095 12.7 3.9 0.12 12.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ran-binding PF05508.11 KXZ44865.1 - 0.11 11.4 5.1 0.14 11.1 5.1 1.0 1 0 0 1 1 1 0 RanGTP-binding protein DivIC PF04977.15 KXZ44865.1 - 0.12 12.2 9.1 0.17 11.6 9.1 1.4 1 0 0 1 1 1 0 Septum formation initiator TMPIT PF07851.13 KXZ44865.1 - 0.16 11.2 6.1 0.16 11.2 6.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein RNA_lig_T4_1 PF09511.10 KXZ44865.1 - 0.17 11.7 2.2 0.21 11.4 2.2 1.0 1 0 0 1 1 1 0 RNA ligase PEX11 PF05648.14 KXZ44865.1 - 0.22 11.0 1.8 0.25 10.8 1.8 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Tho2 PF11262.8 KXZ44865.1 - 0.25 10.5 4.0 0.29 10.3 4.0 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4199 PF13858.6 KXZ44865.1 - 0.42 11.0 0.9 0.45 10.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4757 PF15949.5 KXZ44865.1 - 0.43 11.0 9.6 0.52 10.8 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) FlaC_arch PF05377.11 KXZ44865.1 - 0.82 10.1 8.2 1.7 9.1 8.2 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2681 PF10883.8 KXZ44865.1 - 1.3 9.5 10.7 1.8 9.0 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) SAPIS-gp6 PF16722.5 KXZ44865.1 - 2 8.9 11.1 2.9 8.4 11.1 1.2 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus FliD_N PF02465.18 KXZ44865.1 - 7.8 7.3 9.4 8 7.2 9.4 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus LRR_8 PF13855.6 KXZ44866.1 - 9.4e-10 38.1 6.0 2.3e-05 24.1 0.2 4.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 KXZ44866.1 - 2e-08 34.4 4.1 0.0017 18.7 0.0 5.1 3 3 3 6 6 6 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXZ44866.1 - 7e-08 32.2 2.2 3.6e-07 30.0 2.2 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ44866.1 - 0.00076 19.3 0.2 0.84 9.6 0.0 2.7 2 0 0 2 2 2 2 F-box domain LRR_6 PF13516.6 KXZ44866.1 - 0.00093 19.1 0.9 20 5.5 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 KXZ44866.1 - 0.082 13.5 6.2 17 6.5 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 KXZ44866.1 - 0.15 11.6 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat Pkinase PF00069.25 KXZ44867.1 - 3.4e-09 36.4 0.0 5.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44867.1 - 0.00062 19.1 0.0 0.0025 17.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXZ44867.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KXZ44867.1 - 0.052 13.5 0.0 0.052 13.5 0.0 3.7 4 1 0 5 5 5 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ44867.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GAS PF13851.6 KXZ44868.1 - 0.0013 18.1 12.9 0.0099 15.3 1.0 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 KXZ44868.1 - 0.0026 17.3 3.9 0.0026 17.3 3.9 1.6 2 0 0 2 2 2 1 Leucine zipper TSC22 PF01166.18 KXZ44868.1 - 0.026 14.8 4.8 1.8 8.9 0.4 3.8 4 0 0 4 4 3 0 TSC-22/dip/bun family bZIP_2 PF07716.15 KXZ44868.1 - 0.043 13.9 0.7 0.043 13.9 0.7 4.5 4 0 0 4 4 4 0 Basic region leucine zipper DUF4618 PF15397.6 KXZ44868.1 - 0.083 12.3 10.2 8.8 5.7 7.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) ATG16 PF08614.11 KXZ44868.1 - 0.26 11.5 23.7 0.017 15.3 15.9 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 KXZ44868.1 - 0.52 10.7 6.4 2.3 8.6 1.3 3.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hemerythrin PF01814.23 KXZ44868.1 - 0.58 10.8 13.0 1.4 9.5 11.4 2.3 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Spc7 PF08317.11 KXZ44868.1 - 0.8 8.5 16.0 0.11 11.3 3.7 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 KXZ44868.1 - 1.3 8.3 19.1 5.4 6.3 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) zf-C4H2 PF10146.9 KXZ44868.1 - 1.3 9.3 9.3 1.7 8.9 7.5 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein PHM7_cyt PF14703.6 KXZ44868.1 - 1.8 8.8 4.9 7.1 6.8 4.6 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Lebercilin PF15619.6 KXZ44868.1 - 2 8.0 20.9 1 9.0 17.9 2.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PilO PF04350.13 KXZ44868.1 - 2.4 8.3 6.6 0.45 10.7 1.6 2.3 2 1 0 3 3 2 0 Pilus assembly protein, PilO DUF812 PF05667.11 KXZ44868.1 - 2.8 6.7 15.7 2 7.2 11.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) KASH_CCD PF14662.6 KXZ44868.1 - 3 7.6 15.0 3.2 7.5 12.5 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 KXZ44868.1 - 5 7.2 11.9 46 4.0 11.8 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 KXZ44868.1 - 5.8 6.9 25.2 0.83 9.7 13.6 3.5 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SOGA PF11365.8 KXZ44868.1 - 7.9 7.7 15.6 14 6.9 9.1 3.1 2 1 0 3 3 3 0 Protein SOGA Seryl_tRNA_N PF02403.22 KXZ44868.1 - 8.5 6.7 14.8 8.2 6.7 9.4 3.1 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NAD_binding_10 PF13460.6 KXZ44869.1 - 3.6e-34 118.3 0.1 3.6e-34 118.3 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXZ44869.1 - 2.8e-11 43.4 0.1 0.0002 21.0 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 KXZ44869.1 - 0.00011 21.3 0.0 0.021 13.8 0.0 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KXZ44869.1 - 0.0035 17.5 0.1 0.0075 16.4 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KXZ44869.1 - 0.012 15.1 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Peptidase_M24 PF00557.24 KXZ44871.1 - 2.4e-54 184.2 1.1 2.9e-54 184.0 1.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KXZ44871.1 - 1.4e-16 60.5 6.4 3e-16 59.4 6.4 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXZ44871.1 - 6.1e-05 23.0 7.2 0.00014 21.8 7.2 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KXZ44871.1 - 0.031 14.1 4.6 0.069 13.0 4.6 1.6 1 0 0 1 1 1 0 HIT zinc finger DnaJ PF00226.31 KXZ44873.1 - 8.5e-17 61.0 0.5 1.4e-16 60.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain FAST_1 PF06743.15 KXZ44874.1 - 0.0045 16.9 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 DUF5337 PF17272.2 KXZ44874.1 - 0.27 11.1 1.6 0.68 9.8 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5337) CMAS PF02353.20 KXZ44875.1 - 8.9e-75 251.5 0.0 1.3e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Amino_oxidase PF01593.24 KXZ44875.1 - 1.3e-16 60.9 2.9 9.6e-14 51.5 2.9 3.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Methyltransf_25 PF13649.6 KXZ44875.1 - 3.2e-16 59.8 0.0 1.1e-15 58.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ44875.1 - 8.8e-15 55.1 0.0 1.7e-13 51.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_8 PF13450.6 KXZ44875.1 - 1.7e-14 53.8 0.0 6.6e-14 51.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_31 PF13847.6 KXZ44875.1 - 1.9e-10 40.7 0.0 5.2e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ44875.1 - 1.3e-09 38.7 0.0 2.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ44875.1 - 5.1e-09 36.2 0.0 9.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 KXZ44875.1 - 5.6e-07 29.5 0.2 5.6e-07 29.5 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ44875.1 - 9.5e-06 24.9 0.2 2.1e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXZ44875.1 - 8.5e-05 21.9 0.1 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ44875.1 - 0.00011 21.7 0.3 0.0002 20.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXZ44875.1 - 0.0012 18.2 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXZ44875.1 - 0.0034 16.7 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXZ44875.1 - 0.0045 16.1 0.1 0.0071 15.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXZ44875.1 - 0.0054 16.7 0.2 2 8.4 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXZ44875.1 - 0.0082 14.9 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Methyltransf_24 PF13578.6 KXZ44875.1 - 0.0095 17.0 0.1 0.11 13.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Pyr_redox_3 PF13738.6 KXZ44875.1 - 0.015 14.6 0.0 0.063 12.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ44875.1 - 0.026 13.7 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KXZ44875.1 - 0.027 15.0 0.0 0.077 13.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_15 PF09445.10 KXZ44875.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 KXZ44875.1 - 0.054 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KXZ44875.1 - 0.055 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase NAD_binding_7 PF13241.6 KXZ44875.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding IQ PF00612.27 KXZ44876.1 - 9.2e-55 177.3 134.4 3.6e-06 26.3 0.4 18.4 17 0 0 17 17 17 17 IQ calmodulin-binding motif CH PF00307.31 KXZ44876.1 - 2.7e-10 40.4 0.0 1.6e-06 28.3 0.0 4.2 3 1 0 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KXZ44876.1 - 3.2e-05 23.7 0.0 0.00021 21.1 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain SPOC PF07744.13 KXZ44876.1 - 0.089 12.7 2.2 5.5 6.9 0.0 2.6 2 0 0 2 2 2 0 SPOC domain Pkinase PF00069.25 KXZ44878.1 - 4.2e-17 62.4 0.0 6.8e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ44878.1 - 8.6e-10 38.0 0.0 1.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ44878.1 - 8.6e-05 21.9 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ44878.1 - 0.023 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ44878.1 - 0.032 14.1 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ44878.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Vps5 PF09325.10 KXZ44879.1 - 2.3e-27 96.1 4.8 3.8e-27 95.4 4.8 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXZ44879.1 - 3.4e-25 88.2 0.0 6.7e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 PX domain BAR PF03114.18 KXZ44879.1 - 3.6e-06 26.8 5.6 2.6e-05 24.0 6.0 2.3 2 1 0 2 2 2 1 BAR domain T4_Gp59_N PF08993.10 KXZ44879.1 - 0.026 14.9 0.0 0.079 13.4 0.0 1.8 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase CCDC-167 PF15188.6 KXZ44879.1 - 0.3 11.5 6.2 2 8.8 3.8 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 SOAR PF16533.5 KXZ44879.1 - 0.51 10.3 8.0 0.56 10.2 0.9 3.3 3 1 0 3 3 3 0 STIM1 Orai1-activating region TMF_DNA_bd PF12329.8 KXZ44879.1 - 0.57 10.2 3.9 67 3.6 0.4 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PDDEXK_1 PF12705.7 KXZ44879.1 - 1.1 9.1 5.2 2.7 7.8 5.0 1.9 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Spc7 PF08317.11 KXZ44879.1 - 1.2 7.9 10.3 0.48 9.3 2.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KXZ44879.1 - 1.5 8.1 9.9 0.28 10.5 0.8 2.6 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding ARGLU PF15346.6 KXZ44879.1 - 2.5 8.0 12.1 2.9 7.8 5.7 2.4 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DHR10 PF18595.1 KXZ44879.1 - 2.5 8.2 12.1 6 7.0 3.7 2.7 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain MscS_porin PF12795.7 KXZ44879.1 - 6 6.3 21.5 0.39 10.2 5.4 2.4 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain PK PF00224.21 KXZ44880.1 - 2.1e-69 234.1 0.0 3.2e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXZ44880.1 - 1e-19 70.9 0.0 5e-19 68.7 0.0 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXZ44880.1 - 0.044 12.9 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family V-SNARE_C PF12352.8 KXZ44881.1 - 9.9e-12 45.0 0.2 2.4e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus HeLo PF14479.6 KXZ44881.1 - 0.032 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Proteasome PF00227.26 KXZ44882.1 - 9.9e-30 103.4 0.1 1.2e-29 103.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Arm PF00514.23 KXZ44883.1 - 3.5e-33 112.6 15.5 5.8e-08 32.5 0.0 9.3 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXZ44883.1 - 2.4e-14 53.4 16.7 8.8e-05 22.9 0.1 5.9 3 2 2 5 5 5 4 HEAT-like repeat HEAT PF02985.22 KXZ44883.1 - 4.6e-11 42.0 1.6 0.23 11.8 0.1 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KXZ44883.1 - 1.4e-10 41.4 9.0 0.025 15.0 0.0 5.2 2 2 3 5 5 5 4 HEAT repeats Cnd1 PF12717.7 KXZ44883.1 - 8.7e-07 29.1 0.0 1.1 9.2 0.0 3.7 1 1 2 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXZ44883.1 - 7.3e-05 21.5 0.9 0.29 9.6 0.3 3.4 2 1 1 3 3 3 2 Adaptin N terminal region CHASE6_C PF17150.4 KXZ44883.1 - 0.00029 21.4 0.6 16 6.3 0.0 5.3 5 1 1 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain DNA_alkylation PF08713.11 KXZ44883.1 - 0.0023 17.7 0.0 9.1 5.9 0.0 4.0 2 1 1 4 4 4 1 DNA alkylation repair enzyme DUF3731 PF12531.8 KXZ44883.1 - 0.017 15.0 2.0 6.1 6.6 0.1 3.5 2 2 0 3 3 3 0 DNA-K related protein CLASP_N PF12348.8 KXZ44883.1 - 0.022 14.4 0.0 0.31 10.6 0.0 2.7 2 1 0 3 3 3 0 CLASP N terminal V-ATPase_H_C PF11698.8 KXZ44883.1 - 0.059 13.5 0.0 31 4.7 0.1 3.6 3 2 1 4 4 4 0 V-ATPase subunit H MMS19_C PF12460.8 KXZ44883.1 - 0.18 10.9 1.6 4.2 6.4 0.0 3.1 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal TPR_12 PF13424.6 KXZ44884.1 - 8.2e-12 45.2 3.4 2.5e-06 27.7 0.8 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ44884.1 - 6e-07 29.1 2.1 0.0061 16.6 0.1 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXZ44884.1 - 6.1e-05 22.4 0.2 0.00014 21.2 0.2 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_1 PF00515.28 KXZ44884.1 - 0.00054 19.7 1.5 0.0061 16.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ44884.1 - 0.00096 19.0 0.1 0.0047 16.9 0.0 2.3 2 0 0 2 2 1 1 Tetratricopeptide repeat BioT2 PF15368.6 KXZ44884.1 - 0.0015 18.5 1.7 0.003 17.5 1.7 1.4 1 0 0 1 1 1 1 Spermatogenesis family BioT2 SPO22 PF08631.10 KXZ44884.1 - 0.0066 16.0 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like Fib_alpha PF08702.10 KXZ44884.1 - 0.021 15.0 1.8 0.072 13.3 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_10 PF13374.6 KXZ44884.1 - 0.054 13.4 0.4 1.8 8.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Nic96 PF04097.14 KXZ44884.1 - 0.063 11.7 0.8 0.091 11.2 0.8 1.1 1 0 0 1 1 1 0 Nup93/Nic96 Alpha-E PF04168.12 KXZ44884.1 - 0.17 11.7 0.9 0.24 11.1 0.2 1.6 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. Phage_GPO PF05929.11 KXZ44884.1 - 0.26 10.9 5.3 0.36 10.4 0.8 2.3 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Tmemb_cc2 PF10267.9 KXZ44884.1 - 0.34 10.0 7.0 0.45 9.6 3.3 2.1 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein TPR_16 PF13432.6 KXZ44884.1 - 0.37 11.5 0.0 0.37 11.5 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Syntaxin-6_N PF09177.11 KXZ44884.1 - 0.4 11.3 4.8 55 4.4 3.0 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TPR_14 PF13428.6 KXZ44884.1 - 0.44 11.5 0.0 0.44 11.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Trimer_CC PF08954.11 KXZ44884.1 - 1.3 8.6 7.0 0.84 9.2 0.1 3.3 3 0 0 3 3 3 0 Trimerisation motif DUF444 PF04285.12 KXZ44884.1 - 3.9 6.5 5.6 8.2 5.4 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF444) CCDC53 PF10152.9 KXZ44884.1 - 5.8 7.3 12.8 3.3 8.1 1.4 3.1 3 1 0 3 3 3 0 Subunit CCDC53 of WASH complex Imm-NTF2 PF15655.6 KXZ44887.1 - 0.027 14.8 0.9 0.045 14.0 0.9 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein Glypican PF01153.19 KXZ44887.1 - 0.2 10.4 2.0 0.3 9.9 2.0 1.2 1 0 0 1 1 1 0 Glypican K_channel_TID PF07941.11 KXZ44887.1 - 1.6 9.2 14.7 0.24 11.9 7.4 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Tom37 PF10568.9 KXZ44889.1 - 0.16 12.3 0.8 0.3 11.4 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein RRM_1 PF00076.22 KXZ44890.1 - 1.4e-19 69.7 0.1 2e-19 69.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ44890.1 - 2e-06 27.8 0.0 3.8e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KXZ44890.1 - 0.00058 19.5 0.0 0.0007 19.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Autotransporter PF03797.19 KXZ44890.1 - 0.016 14.9 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Autotransporter beta-domain Syd PF07348.12 KXZ44890.1 - 0.12 12.0 0.0 3.7 7.2 0.0 2.2 1 1 1 2 2 2 0 Syd protein (SUKH-2) dsrm PF00035.26 KXZ44891.1 - 6e-12 46.1 1.2 2.9e-10 40.7 0.0 3.3 3 0 0 3 3 3 1 Double-stranded RNA binding motif NIF PF03031.18 KXZ44891.1 - 3.5e-06 26.9 0.0 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PAPA-1 PF04795.12 KXZ44891.1 - 0.022 15.6 2.0 0.078 13.8 2.0 2.0 1 0 0 1 1 1 0 PAPA-1-like conserved region PHM7_cyt PF14703.6 KXZ44892.1 - 2.3e-05 24.7 0.0 0.02 15.1 0.0 2.3 1 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 KXZ44892.1 - 4.7e-05 23.1 0.0 0.0077 16.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KXZ44892.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NeA_P2 PF12312.8 KXZ44892.1 - 0.19 11.2 5.2 1.5 8.2 0.5 2.4 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Methyltransf_21 PF05050.12 KXZ44893.1 - 9.1e-09 35.6 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Septin PF00735.18 KXZ44894.1 - 0.00079 18.8 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Septin DUF2052 PF09747.9 KXZ44894.1 - 0.33 11.1 3.1 0.61 10.2 3.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) IIGP PF05049.13 KXZ44894.1 - 0.35 9.9 0.4 0.54 9.3 0.0 1.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) zf-RING_2 PF13639.6 KXZ44895.1 - 0.00027 21.2 7.6 0.00054 20.2 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KXZ44895.1 - 0.00027 21.1 4.8 0.00059 20.0 4.8 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.11 KXZ44895.1 - 0.0038 17.5 4.0 0.0089 16.3 4.0 1.6 1 0 0 1 1 1 1 RING-like domain zf-rbx1 PF12678.7 KXZ44895.1 - 0.012 15.9 5.9 0.025 14.8 5.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXZ44895.1 - 0.022 14.8 1.5 0.041 13.9 1.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KXZ44895.1 - 0.051 13.5 4.6 0.09 12.7 4.6 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KXZ44895.1 - 0.17 12.0 5.7 0.42 10.8 5.7 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 KXZ44895.1 - 0.95 9.4 7.3 1.7 8.6 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXZ44895.1 - 1 9.0 5.9 2.2 8.0 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KXZ44896.1 - 7.9e-21 74.5 0.0 5.8e-11 42.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ44896.1 - 2.5e-16 59.5 1.9 2.3e-06 27.8 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ44896.1 - 9.7e-14 51.6 0.5 0.00016 22.1 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44896.1 - 1.7e-13 49.4 0.1 0.054 14.1 0.0 4.6 4 1 1 5 5 5 3 Ankyrin repeat Ank PF00023.30 KXZ44896.1 - 5.6e-12 45.5 0.1 0.0069 16.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DnaJ PF00226.31 KXZ44898.1 - 4.1e-12 46.0 0.0 7.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain rRNA_proc-arch PF13234.6 KXZ44898.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 rRNA-processing arch domain SAM_1 PF00536.30 KXZ44899.1 - 1e-08 35.5 0.0 2.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXZ44899.1 - 2e-08 34.2 0.0 4.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_6 PF13405.6 KXZ44899.1 - 0.0004 20.1 0.1 0.0014 18.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ44899.1 - 0.0027 18.1 0.1 0.0067 16.9 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ44899.1 - 0.02 14.4 0.2 0.046 13.2 0.2 1.6 1 0 0 1 1 1 0 EF hand DUF2380 PF09533.10 KXZ44899.1 - 0.027 14.1 4.1 0.32 10.6 0.6 3.5 4 1 1 5 5 5 0 Predicted lipoprotein of unknown function (DUF2380) EF-hand_1 PF00036.32 KXZ44899.1 - 0.028 14.0 0.1 0.067 12.8 0.1 1.6 1 0 0 1 1 1 0 EF hand FYVE PF01363.21 KXZ44899.1 - 4.8 7.4 10.4 9.7 6.4 10.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger FAST_1 PF06743.15 KXZ44900.1 - 0.01 15.8 9.4 6 6.9 0.0 6.7 7 2 2 9 9 9 0 FAST kinase-like protein, subdomain 1 PBP1_TM PF14812.6 KXZ44900.1 - 0.79 10.1 2.6 1.7 9.1 2.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chorion_3 PF05387.11 KXZ44901.1 - 6.1 6.4 5.3 8.3 6.0 5.3 1.1 1 0 0 1 1 1 0 Chorion family 3 2OG-FeII_Oxy_3 PF13640.6 KXZ44902.1 - 3e-15 56.9 0.0 5.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L23eN PF03939.13 KXZ44903.1 - 1.5e-15 57.1 9.3 1.5e-15 57.1 9.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KXZ44903.1 - 4.9e-15 55.7 2.3 4.9e-15 55.7 2.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L23 FAD_binding_8 PF08022.12 KXZ44903.1 - 0.021 14.9 0.1 0.026 14.6 0.1 1.1 1 0 0 1 1 1 0 FAD-binding domain MoCF_biosynth PF00994.24 KXZ44905.1 - 2.7e-29 101.7 0.0 3.5e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain Snf7 PF03357.21 KXZ44906.1 - 4.2e-34 117.6 22.5 4.2e-34 117.6 22.5 1.3 2 0 0 2 2 2 1 Snf7 eIF-5_eIF-2B PF01873.17 KXZ44906.1 - 0.74 9.7 4.7 3.1 7.7 1.1 2.3 1 1 0 2 2 2 0 Domain found in IF2B/IF5 CheZ PF04344.13 KXZ44906.1 - 1.6 8.6 13.8 42 4.0 13.8 2.3 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ FCH PF00611.23 KXZ44906.1 - 2.2 8.7 8.0 4.8 7.5 8.0 1.6 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain PCRF PF03462.18 KXZ44906.1 - 5.6 6.8 18.0 7 6.5 8.5 2.3 1 1 0 2 2 2 0 PCRF domain Acetyltransf_1 PF00583.25 KXZ44907.1 - 4.7e-11 43.0 0.3 9.6e-11 41.9 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ44907.1 - 2e-08 34.5 0.0 4.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ44907.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ44907.1 - 0.0042 17.0 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF1995 PF09353.10 KXZ44909.1 - 9.1e-33 114.0 0.0 1.1e-32 113.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Zip PF02535.22 KXZ44910.1 - 9.6e-08 31.6 5.7 5.9e-07 29.0 0.7 4.4 2 1 1 4 4 4 3 ZIP Zinc transporter LON_substr_bdg PF02190.16 KXZ44915.1 - 0.0021 18.0 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain FAM199X PF15814.5 KXZ44916.1 - 0.011 14.8 4.3 0.017 14.2 4.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Ank_4 PF13637.6 KXZ44917.1 - 4.2e-12 46.3 0.2 0.0031 18.1 0.1 6.2 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ44917.1 - 1.3e-07 32.1 0.0 0.33 11.6 0.0 4.2 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ44917.1 - 0.00014 22.0 0.0 35 5.4 0.0 6.1 7 0 0 7 7 7 1 Ankyrin repeat JmjC PF02373.22 KXZ44918.1 - 1.5e-20 73.7 0.0 2.1e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Guanylate_cyc PF00211.20 KXZ44919.1 - 0.0013 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain OMP_b-brl PF13505.6 KXZ44919.1 - 0.077 13.1 2.7 0.11 12.6 2.7 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain TPH PF13868.6 KXZ44920.1 - 1.2e-22 79.9 111.4 1.2e-22 79.9 111.4 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain PSII_Pbs27 PF13326.6 KXZ44921.1 - 2.5e-26 92.7 0.0 2.8e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Photosystem II Pbs27 Actin PF00022.19 KXZ44923.1 - 0.066 11.8 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Actin DNA_pol_B PF00136.21 KXZ44924.1 - 1.2e-32 113.3 0.0 1.4e-31 109.7 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase family B DUF2764 PF10962.8 KXZ44925.1 - 0.2 11.1 0.0 0.22 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Actin PF00022.19 KXZ44926.1 - 0.29 9.7 0.0 0.43 9.1 0.0 1.2 1 0 0 1 1 1 0 Actin EccE PF11203.8 KXZ44927.1 - 0.086 13.2 3.7 2.4 8.5 0.3 2.1 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE LPP PF04728.13 KXZ44929.1 - 0.062 13.7 0.2 0.1 13.0 0.2 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper APC_N_CC PF16689.5 KXZ44929.1 - 0.09 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Arm PF00514.23 KXZ44930.1 - 1.5e-59 196.3 24.3 3.6e-11 42.7 0.0 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXZ44930.1 - 2.4e-19 69.4 15.7 8.9e-06 26.1 0.1 6.6 5 1 1 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 KXZ44930.1 - 3.6e-10 40.1 9.3 0.01 16.2 0.1 5.1 1 1 4 5 5 5 4 HEAT repeats HEAT PF02985.22 KXZ44930.1 - 2.6e-09 36.5 10.7 0.0047 17.1 0.0 7.2 8 0 0 8 8 8 3 HEAT repeat HEAT_PBS PF03130.16 KXZ44930.1 - 0.43 11.4 8.9 5.4 8.0 0.0 5.0 5 1 1 6 6 6 0 PBS lyase HEAT-like repeat MCM PF00493.23 KXZ44931.1 - 6e-96 319.9 0.0 1.8e-95 318.3 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXZ44931.1 - 1.2e-24 86.6 0.0 2.1e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXZ44931.1 - 5.1e-22 78.1 1.0 5.1e-22 78.1 1.0 2.6 3 0 0 3 3 3 1 MCM AAA-lid domain AAA_5 PF07728.14 KXZ44931.1 - 5.3e-08 33.0 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXZ44931.1 - 9.2e-08 31.7 0.1 3.8e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXZ44931.1 - 0.00018 21.3 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.6 KXZ44931.1 - 0.026 15.1 2.0 1.3 9.7 0.3 2.9 1 1 1 2 2 2 0 MCM N-terminal domain AAA_16 PF13191.6 KXZ44931.1 - 0.043 14.2 1.0 0.59 10.5 1.0 2.8 1 1 0 1 1 1 0 AAA ATPase domain PsbY PF06298.11 KXZ44932.1 - 2.8e-13 49.5 14.6 8.3e-07 28.8 1.4 3.1 3 0 0 3 3 3 2 Photosystem II protein Y (PsbY) DUF3830 PF12903.7 KXZ44932.1 - 0.11 12.2 0.1 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) DUF992 PF06186.11 KXZ44932.1 - 0.65 9.8 5.7 9.2 6.1 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF992) DUF5388 PF17363.2 KXZ44932.1 - 1.3 9.2 4.5 30 4.9 0.1 3.1 3 1 1 4 4 4 0 Family of unknown function (DUF5388) Chloroa_b-bind PF00504.21 KXZ44933.1 - 4.8e-49 167.0 0.0 6.4e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ChaC PF04752.12 KXZ44934.1 - 1.7e-36 125.9 0.0 1.7e-34 119.5 0.0 2.3 1 1 0 1 1 1 1 ChaC-like protein Aminotran_1_2 PF00155.21 KXZ44935.1 - 2.2e-37 129.1 0.0 3.2e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AAA PF00004.29 KXZ44936.1 - 6e-28 97.9 0.0 3e-22 79.4 0.0 2.3 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ44936.1 - 3.7e-09 36.3 0.1 3.7e-09 36.3 0.1 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KXZ44936.1 - 4.9e-05 23.8 1.6 0.0057 17.0 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXZ44936.1 - 8.3e-05 22.4 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXZ44936.1 - 9.9e-05 22.4 0.1 0.00048 20.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ44936.1 - 0.00014 22.1 0.1 0.035 14.4 0.1 2.5 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXZ44936.1 - 0.0015 18.0 0.2 0.0033 16.8 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXZ44936.1 - 0.0047 17.1 0.1 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 KXZ44936.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KXZ44936.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KXZ44936.1 - 0.03 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 KXZ44936.1 - 0.039 13.7 0.6 0.16 11.7 0.6 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ44936.1 - 0.067 13.1 0.4 0.13 12.1 0.4 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KXZ44936.1 - 0.068 12.9 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KXZ44936.1 - 0.071 12.9 0.1 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXZ44936.1 - 0.15 12.6 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ44936.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXZ44936.1 - 0.25 11.8 0.0 0.44 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DASH_Spc34 PF08657.10 KXZ44937.1 - 3 7.6 5.6 5.7 6.7 5.6 1.4 1 0 0 1 1 1 0 DASH complex subunit Spc34 TPR_9 PF13371.6 KXZ44938.1 - 0.012 15.7 0.2 0.017 15.2 0.2 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KXZ44939.1 - 1.2e-23 84.8 9.5 1.7e-23 84.4 9.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ44939.1 - 3.3e-22 79.4 0.2 6e-22 78.5 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ44939.1 - 2.6e-20 72.7 0.2 2.8e-17 62.8 0.2 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KXZ44939.1 - 7e-05 22.6 1.9 0.00014 21.6 1.9 1.5 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KXZ44939.1 - 0.00046 19.2 0.0 0.00067 18.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 KXZ44939.1 - 0.0005 19.7 0.0 0.0026 17.3 0.0 1.9 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KXZ44939.1 - 0.001 19.0 0.1 0.48 10.3 0.2 2.9 2 1 0 2 2 2 1 Serine hydrolase Peptidase_S15 PF02129.18 KXZ44939.1 - 0.0031 17.1 1.8 0.0048 16.5 1.8 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KXZ44939.1 - 0.0047 16.8 0.0 2.8 7.7 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXZ44939.1 - 0.018 14.5 0.3 0.37 10.2 0.4 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF676 PF05057.14 KXZ44939.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AXE1 PF05448.12 KXZ44939.1 - 0.035 12.8 2.4 0.12 11.0 0.1 2.1 1 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 KXZ44939.1 - 0.042 13.9 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.11 KXZ44939.1 - 0.093 11.7 0.4 0.14 11.1 0.2 1.3 1 1 0 1 1 1 0 Chlorophyllase Abhydro_lipase PF04083.16 KXZ44939.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF2920 PF11144.8 KXZ44939.1 - 0.19 10.8 0.4 2.4 7.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) FMN_red PF03358.15 KXZ44940.1 - 6.1e-13 48.8 0.0 9.1e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXZ44940.1 - 2.4e-05 24.1 0.0 3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KXZ44940.1 - 0.00015 22.0 0.3 0.00046 20.4 0.3 1.8 1 1 0 1 1 1 1 Flavodoxin PqiA PF04403.13 KXZ44940.1 - 0.023 14.5 0.2 0.038 13.8 0.2 1.3 1 0 0 1 1 1 0 Paraquat-inducible protein A FMN_red PF03358.15 KXZ44941.1 - 5.5e-15 55.4 0.1 8.9e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXZ44941.1 - 1.4e-07 31.4 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KXZ44941.1 - 0.054 13.7 0.3 0.16 12.1 0.3 2.0 1 1 0 1 1 1 0 Flavodoxin PqiA PF04403.13 KXZ44941.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Paraquat-inducible protein A TagA PF12561.8 KXZ44941.1 - 0.17 12.3 0.0 0.87 10.0 0.0 2.0 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain Trypsin PF00089.26 KXZ44942.1 - 3.8e-05 23.6 0.1 3.8e-05 23.6 0.1 2.3 3 0 0 3 3 3 1 Trypsin Mito_fiss_reg PF05308.11 KXZ44942.1 - 0.42 10.7 1.4 0.7 9.9 1.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXZ44942.1 - 8.3 5.8 9.7 0.79 9.1 4.7 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RibD_C PF01872.17 KXZ44943.1 - 1.5e-39 135.9 0.0 2.2e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain DUF1768 PF08719.11 KXZ44943.1 - 1.1e-26 94.1 0.0 4.8e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1768) dCMP_cyt_deam_1 PF00383.23 KXZ44943.1 - 3.6e-05 23.6 0.2 6.6e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Peptidase_M11 PF05548.11 KXZ44944.1 - 9.9e-13 47.9 0.1 1.5e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_5 PF13688.6 KXZ44944.1 - 0.0018 18.5 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 KXZ44944.1 - 0.0024 17.5 0.6 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 KXZ44944.1 - 0.0029 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KXZ44944.1 - 0.0069 15.4 0.0 0.0086 15.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 KXZ44944.1 - 0.0073 16.8 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KXZ44944.1 - 0.009 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin PF01421.19 KXZ44944.1 - 0.03 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.24 KXZ44944.1 - 0.035 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M11 PF05548.11 KXZ44945.1 - 7.4e-15 54.9 0.0 1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 KXZ44945.1 - 0.018 14.0 0.3 0.029 13.3 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 KXZ44945.1 - 0.022 14.9 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KXZ44945.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 KXZ44945.1 - 0.045 13.4 0.1 0.097 12.3 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KXZ44945.1 - 0.07 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M11 PF05548.11 KXZ44946.1 - 1.3e-14 54.0 0.1 2.1e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Cu-binding_MopE PF11617.8 KXZ44946.1 - 0.00019 21.5 2.6 0.00064 19.8 2.6 1.9 1 0 0 1 1 1 1 Putative metal-binding motif Reprolysin_3 PF13582.6 KXZ44946.1 - 0.0012 19.3 0.7 0.0091 16.5 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXZ44946.1 - 0.0013 19.0 0.1 0.0028 17.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KXZ44946.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 KXZ44946.1 - 0.016 14.9 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KXZ44946.1 - 0.021 13.8 0.8 0.021 13.8 0.8 2.4 2 1 1 3 3 3 0 Peptidase M66 Metallopep PF12044.8 KXZ44946.1 - 0.052 12.2 0.2 0.078 11.6 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase family LMBR1 PF04791.16 KXZ44947.1 - 2e-79 267.8 3.4 3e-52 178.2 0.0 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein Jag_N PF14804.6 KXZ44947.1 - 0.049 14.0 1.0 0.093 13.1 1.0 1.4 1 0 0 1 1 1 0 Jag N-terminus WD40 PF00400.32 KXZ44948.1 - 6.9e-17 61.5 18.9 0.13 13.2 0.1 10.2 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ44948.1 - 5.8e-11 42.5 0.3 0.0045 17.3 0.0 5.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain MT-A70 PF05063.14 KXZ44950.1 - 1.2e-06 28.6 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 MT-A70 DUF5567 PF17722.1 KXZ44951.1 - 1.5e-05 25.0 0.0 0.00027 20.9 0.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5567) LCIB_C_CA PF18599.1 KXZ44952.1 - 4.8e-80 268.0 0.0 6.4e-80 267.6 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Guanylate_cyc PF00211.20 KXZ44953.1 - 3.4e-09 36.6 0.0 7.1e-05 22.5 0.0 3.1 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain DUF3110 PF11360.8 KXZ44953.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Tim17 PF02466.19 KXZ44954.1 - 8.7e-25 87.3 2.5 8.7e-25 87.3 2.5 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family HORMA PF02301.18 KXZ44956.1 - 2.3e-52 177.7 0.0 3.3e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 HORMA domain NUC153 PF08159.12 KXZ44957.1 - 4e-14 52.1 18.8 9.4e-09 34.9 3.5 3.5 3 0 0 3 3 3 3 NUC153 domain Pkinase PF00069.25 KXZ44958.1 - 9e-57 192.4 0.0 1e-56 192.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ44958.1 - 1.4e-41 142.5 0.0 1.7e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ44958.1 - 0.0086 15.4 0.1 0.015 14.6 0.1 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ44958.1 - 0.018 15.0 0.6 0.48 10.3 0.1 2.7 2 2 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ44958.1 - 0.032 13.2 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXZ44958.1 - 0.085 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APG6_N PF17675.1 KXZ44960.1 - 0.014 15.9 16.0 0.014 15.9 16.0 6.3 1 1 4 5 5 5 0 Apg6 coiled-coil region Noelin-1 PF12308.8 KXZ44960.1 - 0.92 9.5 13.8 3.3 7.7 3.7 4.0 2 1 1 3 3 3 0 Neurogenesis glycoprotein HALZ PF02183.18 KXZ44961.1 - 0.017 15.4 13.1 0.14 12.4 0.5 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper Ank_2 PF12796.7 KXZ44962.1 - 1.4e-18 67.2 1.5 0.00027 21.5 0.2 4.3 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ44962.1 - 8.1e-14 51.8 2.6 0.061 13.9 0.0 8.1 4 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ44962.1 - 5.6e-09 35.5 2.5 14 6.6 0.0 8.4 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ44962.1 - 0.00044 20.5 2.8 1.2 9.5 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) QSregVF_b PF12843.7 KXZ44962.1 - 0.042 13.7 0.1 89 3.1 0.0 4.0 4 0 0 4 4 4 0 Putative quorum-sensing-regulated virulence factor SymE_toxin PF08845.10 KXZ44962.1 - 0.45 10.6 3.5 0.86 9.7 0.4 3.0 3 0 0 3 3 3 0 Toxin SymE, type I toxin-antitoxin system Defensin_4 PF07936.12 KXZ44962.1 - 0.77 9.7 9.4 16 5.5 0.1 4.5 4 0 0 4 4 4 0 Potassium-channel blocking toxin Upf2 PF04050.14 KXZ44963.1 - 1.1e-05 26.2 5.8 0.00049 20.8 0.5 2.2 2 0 0 2 2 2 2 Up-frameshift suppressor 2 Phage_GP20 PF06810.11 KXZ44964.1 - 0.0044 16.8 1.2 0.0069 16.2 1.2 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 MIF4G PF02854.19 KXZ44964.1 - 0.008 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain DUF1319 PF07028.11 KXZ44964.1 - 0.019 15.2 1.6 0.028 14.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Med15_fungi PF05397.12 KXZ44964.1 - 0.022 15.0 0.9 0.04 14.2 0.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 DUF3818 PF12825.7 KXZ44964.1 - 0.025 13.6 0.3 0.028 13.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) MCU PF04678.13 KXZ44965.1 - 5.9e-37 127.5 2.8 7.1e-37 127.2 2.8 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Use1 PF09753.9 KXZ44965.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 RRM_1 PF00076.22 KXZ44966.1 - 1.2e-14 53.9 0.0 1.6e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ44966.1 - 0.018 15.2 0.0 0.045 13.9 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Voltage_CLC PF00654.20 KXZ44967.1 - 7e-75 252.5 22.7 1.3e-74 251.6 16.2 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KXZ44967.1 - 3.1e-08 33.9 0.5 4.1e-06 27.1 0.0 3.3 3 0 0 3 3 3 1 CBS domain DUF2407_C PF13373.6 KXZ44967.1 - 6.2 7.0 8.6 11 6.2 2.0 3.2 4 0 0 4 4 4 0 DUF2407 C-terminal domain AP2 PF00847.20 KXZ44968.1 - 1.2e-09 38.2 0.6 1.8e-09 37.7 0.6 1.3 1 0 0 1 1 1 1 AP2 domain Chorion_3 PF05387.11 KXZ44970.1 - 0.012 15.3 0.2 0.012 15.3 0.2 1.1 1 0 0 1 1 1 0 Chorion family 3 Metallophos PF00149.28 KXZ44973.1 - 3.5e-08 34.2 0.1 6e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ44973.1 - 1.1e-07 32.2 0.2 3.7e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase superfamily domain INSIG PF07281.12 KXZ44974.1 - 0.0028 17.3 0.2 0.0041 16.8 0.2 1.4 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) RCDG1 PF15725.5 KXZ44974.1 - 0.0039 17.6 1.1 0.0087 16.5 1.1 1.5 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein MORN PF02493.20 KXZ44975.1 - 1.3e-24 84.5 35.6 2.8e-08 33.2 5.0 7.0 7 0 0 7 7 7 6 MORN repeat CAP_N PF01213.19 KXZ44975.1 - 1.1 8.6 6.8 1.5 8.2 6.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 60KD_IMP PF02096.20 KXZ44976.1 - 7.9e-56 188.5 0.9 9.3e-56 188.3 0.1 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein DUF2062 PF09835.9 KXZ44976.1 - 0.0046 16.8 1.4 0.011 15.7 1.4 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) Acetyltransf_10 PF13673.7 KXZ44977.1 - 1e-06 28.7 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ44977.1 - 4.6e-06 26.9 0.0 5.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ44977.1 - 7.4e-05 23.1 0.0 9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ44977.1 - 0.0075 16.4 0.0 0.0096 16.0 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KXZ44977.1 - 0.041 13.8 0.1 0.06 13.3 0.1 1.3 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 KXZ44977.1 - 0.057 13.1 0.0 0.083 12.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KXZ44977.1 - 0.099 12.6 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Cep57_CLD_2 PF14197.6 KXZ44978.1 - 0.54 10.4 4.6 0.53 10.4 2.1 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF3984 PF13136.6 KXZ44978.1 - 1.4 8.3 7.1 2.6 7.4 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Mito_fiss_reg PF05308.11 KXZ44978.1 - 4.4 7.3 8.1 3.7 7.6 0.4 2.6 3 0 0 3 3 3 0 Mitochondrial fission regulator TEX19 PF15553.6 KXZ44979.1 - 0.075 13.0 0.9 0.13 12.3 0.9 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 HTH_IclR PF09339.10 KXZ44979.1 - 0.076 12.8 0.6 0.28 11.0 0.6 2.1 1 1 0 1 1 1 0 IclR helix-turn-helix domain ACT_6 PF13740.6 KXZ44979.1 - 0.11 12.4 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 ACT domain PHO4 PF01384.20 KXZ44981.1 - 8.7e-97 324.2 23.1 1.2e-96 323.7 23.1 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF4381 PF14316.6 KXZ44981.1 - 1 9.6 12.1 0.32 11.2 3.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Foie-gras_1 PF11817.8 KXZ44984.1 - 6.6e-12 45.6 0.0 1.3e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 SAP130_C PF16014.5 KXZ44984.1 - 0.089 11.9 10.4 0.18 10.8 10.4 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus FixG_C PF11614.8 KXZ44984.1 - 0.17 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase SHE3 PF17078.5 KXZ44985.1 - 0.0064 16.2 3.7 0.96 9.1 1.4 2.2 2 0 0 2 2 2 2 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 KXZ44985.1 - 0.0082 16.2 7.8 0.1 12.6 0.9 3.6 1 1 3 4 4 4 1 Protein of unknown function (DUF1664) Filament PF00038.21 KXZ44985.1 - 0.051 13.2 27.2 0.17 11.4 9.1 2.7 1 1 2 3 3 3 0 Intermediate filament protein Fez1 PF06818.15 KXZ44985.1 - 5.7 7.3 28.5 1.6 9.1 4.1 2.1 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KXZ44985.1 - 8 5.2 31.7 4.6 6.0 3.9 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein Atg14 PF10186.9 KXZ44985.1 - 10 5.1 19.3 43 3.0 17.6 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GCS2 PF04107.13 KXZ44986.1 - 2.8e-87 292.7 0.0 4.6e-87 292.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) EamA PF00892.20 KXZ44986.1 - 2e-12 47.4 29.7 1.7e-09 38.0 12.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family TcdA_TcdB_pore PF12920.7 KXZ44986.1 - 0.75 8.0 2.0 1.2 7.3 2.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain PAN_4 PF14295.6 KXZ44987.1 - 7.7e-17 60.9 25.5 3.6e-10 39.6 7.1 2.9 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 KXZ44987.1 - 6.4e-06 26.0 8.0 0.026 14.5 0.5 2.7 2 1 0 2 2 2 2 PAN domain MANEC PF07502.14 KXZ44987.1 - 3 8.2 13.1 0.53 10.6 1.0 2.6 2 1 0 2 2 2 0 MANEC domain RRM_1 PF00076.22 KXZ44988.1 - 3.3e-16 58.8 0.0 4.1e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ44988.1 - 0.013 15.3 0.0 0.072 13.0 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif DbpA PF03880.15 KXZ44990.1 - 0.00087 19.2 0.1 0.0011 18.9 0.1 1.1 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_1 PF00076.22 KXZ44990.1 - 0.12 12.2 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4048 PF13257.6 KXZ44991.1 - 0.011 15.7 7.7 0.028 14.3 7.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) AAA PF00004.29 KXZ44992.1 - 2.4e-43 147.7 0.0 3.9e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXZ44992.1 - 1.4e-22 79.4 0.0 9.8e-22 76.7 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KXZ44992.1 - 3.6e-19 68.6 10.3 1.1e-18 67.1 10.3 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 KXZ44992.1 - 3.8e-06 26.7 0.0 6.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ44992.1 - 2e-05 25.0 0.1 0.0016 18.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXZ44992.1 - 2.1e-05 24.5 0.1 6.8e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ44992.1 - 4.6e-05 23.7 0.1 0.014 15.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KXZ44992.1 - 0.00014 21.2 0.0 0.00027 20.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KXZ44992.1 - 0.00021 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KXZ44992.1 - 0.00031 20.8 0.0 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KXZ44992.1 - 0.00047 19.9 0.1 0.011 15.5 0.0 3.0 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 KXZ44992.1 - 0.0024 18.0 0.0 0.0056 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KXZ44992.1 - 0.0024 18.4 0.1 0.0094 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXZ44992.1 - 0.0042 17.2 0.0 0.0093 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXZ44992.1 - 0.0062 15.8 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KXZ44992.1 - 0.0065 16.1 1.0 0.77 9.3 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KXZ44992.1 - 0.0073 16.1 0.1 0.016 14.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXZ44992.1 - 0.0077 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 KXZ44992.1 - 0.013 14.9 0.0 1.4 8.2 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 KXZ44992.1 - 0.019 14.9 0.0 0.83 9.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 KXZ44992.1 - 0.043 13.2 0.1 9.6 5.5 0.0 2.5 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 KXZ44992.1 - 0.044 13.2 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KXZ44992.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KXZ44992.1 - 0.078 12.7 0.0 0.4 10.4 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 KXZ44992.1 - 0.08 12.4 0.2 0.16 11.4 0.2 1.6 1 1 0 1 1 1 0 PhoH-like protein Use1 PF09753.9 KXZ44992.1 - 0.15 11.8 1.9 0.31 10.7 1.9 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 AAA_7 PF12775.7 KXZ44992.1 - 0.18 11.3 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 KXZ44992.1 - 0.19 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_2 PF07719.17 KXZ44992.1 - 4 7.8 7.7 4.8 7.5 2.7 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.23 KXZ44993.1 - 3.2e-25 88.2 0.1 6.4e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KXZ44993.1 - 0.1 12.7 0.3 0.2 11.8 0.0 1.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold NIF PF03031.18 KXZ44994.1 - 1.1e-09 38.2 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AAA_33 PF13671.6 KXZ44994.1 - 0.00058 20.0 0.1 0.0016 18.6 0.1 1.7 2 0 0 2 2 2 1 AAA domain Cu-binding_MopE PF11617.8 KXZ44995.1 - 0.012 15.7 9.6 0.024 14.8 9.6 1.5 1 0 0 1 1 1 0 Putative metal-binding motif DAGAT PF03982.13 KXZ44997.1 - 1.5e-22 79.9 0.0 4.2e-22 78.4 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KXZ44997.1 - 0.00083 19.0 0.1 0.0017 18.0 0.1 1.5 1 1 0 1 1 1 1 Acyltransferase DUF3707 PF12499.8 KXZ44998.1 - 2.1e-18 67.3 8.4 2.3e-18 67.1 7.5 1.5 2 0 0 2 2 2 1 Pherophorin PRIMA1 PF16101.5 KXZ44998.1 - 0.017 15.2 4.4 0.042 13.9 2.6 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Methyltrn_RNA_3 PF02598.17 KXZ44999.1 - 0.27 10.7 0.0 18 4.7 0.0 2.1 2 0 0 2 2 2 0 Putative RNA methyltransferase SMP_LBD PF17047.5 KXZ45000.1 - 0.006 16.1 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KXZ45000.1 - 0.082 13.2 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 C2 domain Leuk-A4-hydro_C PF09127.11 KXZ45002.1 - 5.2e-34 116.7 0.0 7.3e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Helicase_C_3 PF13625.6 KXZ45002.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Peptidase_M1 PF01433.20 KXZ45003.1 - 2.1e-21 76.5 0.0 9.3e-21 74.4 0.0 1.8 1 1 1 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXZ45003.1 - 1.9e-15 57.5 0.0 2.8e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KXZ45003.1 - 0.15 12.4 0.8 2.2 8.7 0.8 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_MA_2 PF13485.6 KXZ45003.1 - 0.21 11.3 0.1 0.41 10.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily Kinesin PF00225.23 KXZ45004.1 - 1.1e-64 218.5 0.0 4.1e-63 213.3 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain UPF0184 PF03670.13 KXZ45004.1 - 0.12 12.8 0.1 2.9 8.3 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Mito_fiss_reg PF05308.11 KXZ45004.1 - 5 7.1 6.6 2.6 8.1 3.0 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Kinesin PF00225.23 KXZ45005.1 - 2.4e-23 82.6 0.0 2.8e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ45005.1 - 1e-16 61.2 0.0 1.4e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding PhoH PF02562.16 KXZ45005.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.14 KXZ45005.1 - 0.22 10.7 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase Lig_chan-Glu_bd PF10613.9 KXZ45006.1 - 8.1e-17 61.5 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 KXZ45006.1 - 9.8e-10 38.5 1.1 2.5e-07 30.6 0.0 2.4 2 1 0 2 2 2 2 Ligand-gated ion channel SBP_bac_3 PF00497.20 KXZ45006.1 - 5.9e-06 25.9 0.0 3.6e-05 23.3 0.0 2.1 1 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_3 PF00497.20 KXZ45007.1 - 2.5e-25 89.2 0.0 4.4e-25 88.4 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 KXZ45007.1 - 1.3e-18 67.3 0.0 5.6e-17 61.9 0.0 2.1 1 1 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KXZ45007.1 - 6.2e-18 65.1 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site PGA2 PF07543.12 KXZ45007.1 - 0.034 14.1 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF202 PF02656.15 KXZ45007.1 - 4.8 7.7 6.9 4.2 7.9 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Abhydrolase_6 PF12697.7 KXZ45010.1 - 1.6e-17 64.9 8.6 1.6e-17 64.9 8.6 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family DNA_photolyase PF00875.18 KXZ45010.1 - 1.3e-15 57.8 0.1 3.1e-15 56.5 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Abhydrolase_1 PF00561.20 KXZ45010.1 - 2.2e-15 57.0 0.3 3.8e-15 56.2 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ45010.1 - 2.9e-13 49.7 0.0 4.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXZ45010.1 - 0.084 12.7 0.1 3.5 7.4 0.0 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Ank_4 PF13637.6 KXZ45011.1 - 6.4e-11 42.6 4.7 1.8 9.3 0.4 7.2 5 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45011.1 - 1.6e-08 35.0 0.4 0.038 14.6 0.0 4.8 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45011.1 - 8.3e-05 22.7 0.6 56 4.8 0.1 6.2 6 0 0 6 6 6 0 Ankyrin repeat ERAP1_C PF11838.8 KXZ45011.1 - 0.031 13.8 1.0 0.16 11.5 0.1 2.5 3 0 0 3 3 3 0 ERAP1-like C-terminal domain Ank_5 PF13857.6 KXZ45011.1 - 1.7 9.1 8.6 67 4.0 0.1 5.7 5 1 2 7 7 7 0 Ankyrin repeats (many copies) FKBP_C PF00254.28 KXZ45013.1 - 1.7e-36 124.4 0.0 2e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4493 PF14900.6 KXZ45013.1 - 0.094 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) FKBP_C PF00254.28 KXZ45014.1 - 1.5e-35 121.3 0.0 1.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CoaE PF01121.20 KXZ45015.1 - 1.9e-21 76.5 0.0 1.4e-10 41.1 0.0 2.2 1 1 1 2 2 2 2 Dephospho-CoA kinase MeaB PF03308.16 KXZ45015.1 - 0.061 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KXZ45015.1 - 0.078 13.1 0.4 1.7 8.8 0.4 2.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXZ45015.1 - 0.16 11.2 0.3 0.76 9.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin TPR_2 PF07719.17 KXZ45016.1 - 8.8e-11 41.1 34.4 0.0019 18.1 1.5 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ45016.1 - 1.2e-08 34.7 14.4 0.11 13.0 0.0 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ45016.1 - 2.3e-07 30.3 15.0 0.00014 21.5 0.4 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ45016.1 - 0.00032 21.3 77.9 0.04 14.7 7.6 9.9 5 2 5 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ45016.1 - 0.0047 16.6 8.4 0.013 15.2 0.2 4.1 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 KXZ45016.1 - 0.0077 16.5 11.3 0.0077 16.5 11.3 7.5 5 3 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45016.1 - 0.085 13.1 15.8 1.4 9.3 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ45016.1 - 0.15 12.1 0.3 0.15 12.1 0.3 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ45016.1 - 0.17 12.0 3.3 2.6 8.2 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat AMP-binding PF00501.28 KXZ45017.1 - 6.2e-60 203.0 0.2 1.6e-57 195.0 0.2 2.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ45017.1 - 6.7e-15 55.8 1.5 3.4e-14 53.6 1.5 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain NHL PF01436.21 KXZ45018.1 - 7.8e-22 76.2 0.1 1e-05 25.3 0.0 5.2 4 0 0 4 4 4 4 NHL repeat Thioredoxin_8 PF13905.6 KXZ45018.1 - 2.6e-09 37.3 0.0 4.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KXZ45018.1 - 1.6e-05 24.9 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family SGL PF08450.12 KXZ45018.1 - 0.00014 21.5 0.0 0.0043 16.7 0.0 2.5 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Redoxin PF08534.10 KXZ45018.1 - 0.00049 19.8 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 KXZ45018.1 - 0.035 14.1 0.0 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Peptidase_S8 PF00082.22 KXZ45019.1 - 7.6e-15 54.9 10.9 3.7e-09 36.3 0.5 2.7 1 1 2 3 3 3 2 Subtilase family BTB_2 PF02214.22 KXZ45020.1 - 0.0001 22.6 0.0 0.00016 22.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Yippee-Mis18 PF03226.14 KXZ45021.1 - 0.00092 19.4 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Acetyltransf_1 PF00583.25 KXZ45022.1 - 3.8e-09 36.8 0.0 5.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ45022.1 - 6.4e-09 36.1 0.1 1.2e-08 35.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ45022.1 - 7.2e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXZ45022.1 - 0.00036 20.6 0.0 0.00056 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ45022.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Peripla_BP_3 PF13377.6 KXZ45022.1 - 0.13 12.5 1.8 12 6.2 0.3 2.4 2 0 0 2 2 2 0 Periplasmic binding protein-like domain RRM_1 PF00076.22 KXZ45024.1 - 4.4e-21 74.5 0.0 6.1e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXZ45024.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cyclophil_like2 PF18050.1 KXZ45024.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like family Trypan_PARP PF05887.11 KXZ45024.1 - 3.5 7.6 12.9 5.9 6.9 12.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Acetyltransf_1 PF00583.25 KXZ45027.1 - 8.9e-10 38.8 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ45027.1 - 2.9e-08 34.0 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ45027.1 - 1.1e-07 31.8 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ45027.1 - 6.9e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXZ45027.1 - 1.1e-05 25.5 0.0 2.5e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ45027.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ank_4 PF13637.6 KXZ45028.1 - 5.5e-18 65.1 5.5 0.15 12.6 0.1 8.5 5 1 4 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45028.1 - 8.8e-17 61.5 1.1 0.012 16.2 0.0 5.8 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45028.1 - 1e-06 28.6 3.7 59 4.7 0.0 8.9 9 0 0 9 9 9 0 Ankyrin repeat F-box PF00646.33 KXZ45028.1 - 0.00088 19.1 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 2 F-box domain Ank PF00023.30 KXZ45028.1 - 0.002 18.5 6.6 40 4.9 0.0 5.9 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 KXZ45028.1 - 0.23 11.8 15.5 8.1 6.9 0.0 7.8 8 3 3 11 11 11 0 Ankyrin repeats (many copies) SelB-wing_1 PF09105.10 KXZ45028.1 - 0.37 10.8 3.1 28 4.8 0.1 3.5 3 0 0 3 3 3 0 Elongation factor SelB, winged helix DUF3246 PF11596.8 KXZ45030.1 - 0.19 11.1 2.8 0.5 9.8 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NAD_binding_8 PF13450.6 KXZ45031.1 - 1.6e-13 50.6 0.2 5.4e-13 49.0 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXZ45031.1 - 1.6e-12 47.5 0.0 2.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXZ45031.1 - 2.8e-07 30.5 1.5 8.4e-07 28.9 1.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ45031.1 - 1.6e-06 27.6 0.2 2.3e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ45031.1 - 1.8e-05 24.0 0.4 0.00012 21.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KXZ45031.1 - 2e-05 24.1 0.1 7.6e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXZ45031.1 - 0.00043 20.8 0.0 0.00092 19.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ45031.1 - 0.00057 18.7 0.0 0.00082 18.2 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KXZ45031.1 - 0.001 18.3 0.3 0.0015 17.7 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXZ45031.1 - 0.0012 18.2 1.1 0.0017 17.7 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KXZ45031.1 - 0.0024 16.8 0.1 0.0035 16.3 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KXZ45031.1 - 0.0028 16.8 0.1 0.0043 16.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXZ45031.1 - 0.0032 16.8 0.4 0.0055 16.0 0.4 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 KXZ45031.1 - 0.016 15.6 0.2 0.05 14.0 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KXZ45031.1 - 0.018 14.3 0.8 0.033 13.5 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXZ45031.1 - 0.038 13.3 0.1 0.056 12.7 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXZ45031.1 - 0.16 11.8 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 KXZ45031.1 - 0.23 10.2 0.0 0.4 9.4 0.0 1.3 1 0 0 1 1 1 0 MCRA family 5-FTHF_cyc-lig PF01812.20 KXZ45032.1 - 1.7e-32 112.8 0.0 2.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 KXZ45033.1 - 8.8e-07 28.7 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calx-beta PF03160.14 KXZ45034.1 - 1.4e-38 131.1 0.1 3.7e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 KXZ45034.1 - 1.2e-15 57.8 7.3 1.2e-15 57.8 7.3 1.8 2 0 0 2 2 2 1 Sodium/calcium exchanger protein eRF1_2 PF03464.15 KXZ45035.1 - 1.3e-43 148.5 0.0 2.1e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXZ45035.1 - 6.9e-35 120.0 0.1 1.6e-34 118.7 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KXZ45035.1 - 2.2e-19 69.7 0.0 3.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KXZ45035.1 - 3.6e-08 33.7 0.0 5.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KXZ45035.1 - 6.3e-08 33.0 0.0 9.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor VanY PF02557.17 KXZ45035.1 - 0.18 11.6 0.1 3.3 7.5 0.1 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase AATF-Che1 PF13339.6 KXZ45036.1 - 5.7e-27 95.1 0.0 3.7e-26 92.5 0.0 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 KXZ45036.1 - 4.6e-18 65.5 0.1 1.2e-17 64.2 0.1 1.7 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Ank_4 PF13637.6 KXZ45037.1 - 8.5e-08 32.6 1.9 2.7 8.7 0.3 5.0 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45037.1 - 6.9e-06 26.6 0.1 0.0034 17.9 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45037.1 - 0.00054 20.2 0.3 22 6.0 0.0 5.2 5 1 1 6 6 6 1 Ankyrin repeat Defensin_4 PF07936.12 KXZ45037.1 - 0.3 11.0 2.1 7.4 6.5 0.5 2.4 2 0 0 2 2 2 0 Potassium-channel blocking toxin Ank_4 PF13637.6 KXZ45039.1 - 1.6e-15 57.3 5.0 0.0021 18.6 0.0 8.1 6 4 1 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45039.1 - 8.2e-14 52.0 0.0 0.00074 20.1 0.0 4.9 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45039.1 - 1.6e-09 37.2 1.9 1 10.1 0.0 8.6 10 0 0 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 KXZ45039.1 - 1.3e-05 25.4 12.3 6.2 7.3 0.0 8.5 5 2 3 9 9 9 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ45040.1 - 8.1e-18 64.5 2.0 0.00039 20.9 0.0 8.1 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45040.1 - 1.1e-15 58.0 0.2 1.1e-07 32.4 0.0 5.1 4 1 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45040.1 - 2.3e-12 45.9 0.1 1.3 9.8 0.0 8.6 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 KXZ45040.1 - 7e-06 26.2 6.6 24 5.4 0.0 8.0 6 2 3 9 9 9 1 Ankyrin repeats (many copies) HAD PF12710.7 KXZ45040.1 - 0.22 11.9 1.1 17 5.8 0.1 3.1 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Ank PF00023.30 KXZ45040.1 - 2.2 8.9 7.9 46 4.7 0.1 5.2 4 2 1 5 5 5 0 Ankyrin repeat GWT1 PF06423.12 KXZ45041.1 - 1.2e-15 57.9 0.0 1.5e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 GWT1 Glycos_transf_1 PF00534.20 KXZ45041.1 - 2.7e-06 27.0 0.0 4.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ45041.1 - 6e-06 26.7 0.1 1.4e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ45041.1 - 0.044 13.8 0.7 0.92 9.5 0.0 2.9 3 0 0 3 3 3 0 Glycosyltransferase Family 4 DUF563 PF04577.14 KXZ45042.1 - 3.4e-14 53.5 0.0 1.8e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF563) DUF1538 PF07556.11 KXZ45043.1 - 2.5e-91 304.7 32.2 2.1e-46 157.9 14.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1538) DUF1538 PF07556.11 KXZ45044.1 - 6.9e-103 342.4 39.6 8.9e-54 182.0 21.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1538) CEP76-C2 PF15627.6 KXZ45045.1 - 9.3e-23 80.5 0.0 1.6e-20 73.3 0.0 2.3 1 1 0 1 1 1 1 CEP76 C2 domain Helitron_like_N PF14214.6 KXZ45046.1 - 0.00015 22.0 0.0 0.00031 21.0 0.0 1.5 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus FtsK_SpoIIIE PF01580.18 KXZ45046.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 KXZ45046.1 - 0.027 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ45046.1 - 0.088 13.2 0.0 0.65 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Maf PF02545.14 KXZ45046.1 - 0.2 11.5 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Maf-like protein Glyco_hydro_9 PF00759.19 KXZ45047.1 - 2.6e-34 119.4 15.1 3.1e-34 119.1 15.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 HC2 PF07382.11 KXZ45048.1 - 2.6 8.1 23.0 4 7.5 23.0 1.3 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Asp-B-Hydro_N PF05279.11 KXZ45048.1 - 3.7 7.6 24.0 4.2 7.4 24.0 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RT_RNaseH_2 PF17919.1 KXZ45049.1 - 1.4e-29 102.1 0.0 2.5e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ45049.1 - 1.3e-25 89.7 0.0 2.6e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ45049.1 - 1.5e-23 83.5 0.0 2.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KXZ45049.1 - 1e-14 54.3 1.1 2e-14 53.4 1.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KXZ45049.1 - 1.2e-12 48.0 0.0 3.4e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KXZ45049.1 - 2.5e-06 27.6 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF4763 PF15960.5 KXZ45050.1 - 0.2 10.9 12.5 0.078 12.3 9.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 KXZ45050.1 - 0.3 9.9 18.5 0.46 9.3 18.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein IKKbetaNEMObind PF12179.8 KXZ45050.1 - 0.35 10.9 1.2 2.3 8.3 0.1 2.7 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain FapA PF03961.13 KXZ45050.1 - 0.4 9.2 3.9 0.45 9.1 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Leu_zip PF15294.6 KXZ45050.1 - 0.47 9.9 14.6 0.91 9.0 14.7 1.4 1 1 0 1 1 1 0 Leucine zipper Cep57_CLD_2 PF14197.6 KXZ45050.1 - 0.82 9.8 18.4 7.3 6.8 14.7 3.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Macoilin PF09726.9 KXZ45050.1 - 2.3 6.7 21.2 3 6.3 21.2 1.1 1 0 0 1 1 1 0 Macoilin family GAS PF13851.6 KXZ45050.1 - 3.4 7.0 21.1 0.93 8.8 17.5 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HAUS-augmin3 PF14932.6 KXZ45050.1 - 3.9 7.0 21.5 0.93 9.0 17.7 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 PV-1 PF06637.11 KXZ45050.1 - 4.5 6.0 26.2 2.1 7.1 14.3 2.0 1 1 1 2 2 2 0 PV-1 protein (PLVAP) PRKG1_interact PF15898.5 KXZ45050.1 - 5.5 7.9 22.3 1.5 9.8 16.1 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 KXZ45050.1 - 8.8 5.6 24.2 14 4.9 24.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KXZ45050.1 - 9 4.1 10.1 10 3.9 10.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CEP76-C2 PF15627.6 KXZ45051.1 - 1.8e-29 102.3 0.0 2.6e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 CEP76 C2 domain Ank_2 PF12796.7 KXZ45052.1 - 1.1e-15 57.9 0.0 6e-07 30.0 0.0 5.2 4 1 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45052.1 - 7.7e-13 48.7 3.9 0.00018 22.0 0.0 7.0 6 3 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45052.1 - 6.7e-11 41.4 0.1 2.7 8.8 0.0 9.1 10 0 0 10 10 10 1 Ankyrin repeat Ank_5 PF13857.6 KXZ45052.1 - 9.4e-09 35.4 2.8 8.5 6.8 0.0 7.4 7 2 1 8 8 8 2 Ankyrin repeats (many copies) Defensin_4 PF07936.12 KXZ45052.1 - 0.15 12.0 8.5 1.4 8.9 0.1 4.2 4 0 0 4 4 4 0 Potassium-channel blocking toxin Ank PF00023.30 KXZ45052.1 - 0.35 11.4 3.1 1.6e+02 3.0 0.1 4.9 6 0 0 6 6 6 0 Ankyrin repeat Acetyltransf_6 PF13480.7 KXZ45052.1 - 4 7.6 5.9 3.3 7.9 0.2 3.1 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Pro_isomerase PF00160.21 KXZ45053.1 - 7.3e-45 153.1 0.0 1e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4922 PF16269.5 KXZ45054.1 - 0.001 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) RAP PF08373.10 KXZ45056.1 - 3.9e-09 36.5 0.0 6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 KXZ45056.1 - 0.05 13.8 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 REase_MTES_1575 Syntaxin PF00804.25 KXZ45057.1 - 3.7e-65 219.4 21.7 5.9e-65 218.7 21.7 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KXZ45057.1 - 8.1e-16 57.8 1.6 8.1e-16 57.8 1.6 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KXZ45057.1 - 7.6e-05 23.0 8.8 7.6e-05 23.0 8.8 2.4 2 1 1 3 3 3 1 Syntaxin-like protein NAPRTase_C PF17956.1 KXZ45057.1 - 0.0083 16.5 1.0 0.0083 16.5 1.0 2.5 2 1 1 3 3 3 1 Nicotinate phosphoribosyltransferase C-terminal domain CwsA PF10814.8 KXZ45057.1 - 0.014 15.6 1.2 0.019 15.2 0.1 1.7 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA RnlB_antitoxin PF15933.5 KXZ45057.1 - 0.034 14.4 0.3 0.14 12.5 0.0 2.3 2 2 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA CRISPR_Cse1 PF09481.10 KXZ45057.1 - 0.035 13.2 2.0 0.056 12.5 2.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) MutS_III PF05192.18 KXZ45057.1 - 0.12 12.6 7.9 0.49 10.6 3.3 2.1 2 0 0 2 2 2 0 MutS domain III DUF3671 PF12420.8 KXZ45057.1 - 0.15 12.1 0.9 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function JIP_LZII PF16471.5 KXZ45057.1 - 0.18 12.0 10.7 1.5 9.1 2.5 3.7 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II Enkurin PF13864.6 KXZ45057.1 - 0.42 11.1 15.7 0.15 12.5 1.8 3.3 2 1 1 3 3 3 0 Calmodulin-binding CDP-OH_P_tran_2 PF08009.11 KXZ45057.1 - 0.59 10.1 4.4 0.94 9.4 4.4 1.2 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 NOG1_N PF17835.1 KXZ45057.1 - 0.92 9.5 13.5 5.3 7.0 5.0 3.1 2 1 2 4 4 4 0 NOG1 N-terminal helical domain ISG65-75 PF11727.8 KXZ45057.1 - 1.4 8.1 16.0 0.39 9.9 11.9 1.9 1 1 2 3 3 3 0 Invariant surface glycoprotein EF1_GNE PF00736.19 KXZ45057.1 - 2 8.7 7.3 2 8.7 1.1 3.7 3 1 1 4 4 4 0 EF-1 guanine nucleotide exchange domain Med8 PF10232.9 KXZ45057.1 - 2.5 7.6 10.8 1.2 8.7 8.5 1.7 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Mis12 PF05859.12 KXZ45057.1 - 3.6 7.6 8.4 0.22 11.6 0.8 2.7 3 1 1 4 4 4 0 Mis12 protein WXG100 PF06013.12 KXZ45057.1 - 4.3 7.6 8.9 2.3 8.5 1.5 3.6 2 2 1 4 4 4 0 Proteins of 100 residues with WXG PI3_PI4_kinase PF00454.27 KXZ45058.1 - 0.00074 19.4 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MRP-L47 PF06984.13 KXZ45059.1 - 0.00025 21.1 3.4 0.0085 16.2 3.4 2.3 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L6e PF01159.19 KXZ45059.1 - 0.046 14.3 0.0 0.057 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e BTG PF07742.12 KXZ45059.1 - 0.059 13.2 0.2 0.084 12.7 0.2 1.3 1 0 0 1 1 1 0 BTG family Esterase PF00756.20 KXZ45060.1 - 4.7e-39 134.5 0.0 5.1e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 Putative esterase CBM53 PF16760.5 KXZ45060.1 - 2.9e-26 91.9 0.0 5.8e-17 62.0 0.1 3.2 3 0 0 3 3 3 2 Starch/carbohydrate-binding module (family 53) Peptidase_S9 PF00326.21 KXZ45060.1 - 0.00019 21.0 1.1 0.099 12.1 0.0 3.1 3 0 0 3 3 3 2 Prolyl oligopeptidase family CBM_25 PF03423.13 KXZ45060.1 - 0.0013 19.0 0.2 0.022 15.0 0.1 2.7 2 0 0 2 2 2 1 Carbohydrate binding domain (family 25) Tannase PF07519.11 KXZ45060.1 - 0.0072 15.3 0.1 1.8 7.4 0.0 2.2 2 0 0 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_2 PF02230.16 KXZ45060.1 - 0.15 11.9 0.0 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase CBM_21 PF03370.13 KXZ45060.1 - 0.15 12.2 0.1 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate/starch-binding module (family 21) RdRP PF05183.12 KXZ45061.1 - 5.8e-88 296.0 0.0 7.2e-47 160.3 0.0 2.2 2 0 0 2 2 2 2 RNA dependent RNA polymerase AAA_11 PF13086.6 KXZ45061.1 - 1e-45 156.6 0.0 1.5e-24 87.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 KXZ45061.1 - 6.7e-45 153.2 0.0 1.1e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ45061.1 - 8.3e-08 32.2 4.1 8.3e-08 32.2 4.1 4.0 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.6 KXZ45061.1 - 1.3e-06 28.8 0.0 4.7e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ45061.1 - 1.4e-05 24.9 0.1 0.16 11.7 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KXZ45061.1 - 0.00063 19.5 0.2 0.0018 18.1 0.2 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KXZ45061.1 - 0.0074 16.7 1.7 0.075 13.4 0.1 3.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KXZ45061.1 - 0.021 14.4 1.6 0.045 13.3 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXZ45061.1 - 0.033 14.5 0.0 0.099 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXZ45061.1 - 0.047 13.1 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.21 KXZ45061.1 - 0.068 12.7 0.1 0.41 10.1 0.1 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 KXZ45061.1 - 0.16 12.5 0.1 0.27 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ45061.1 - 0.34 11.3 1.0 0.74 10.2 1.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) p450 PF00067.22 KXZ45063.1 - 8.5e-37 127.0 0.0 2.5e-20 72.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 AAA_28 PF13521.6 KXZ45063.1 - 1.6e-10 41.4 0.1 4.5e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ45063.1 - 0.0009 19.7 0.1 0.0028 18.1 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KXZ45063.1 - 0.017 14.9 0.3 0.062 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXZ45063.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 NTPase CbiA PF01656.23 KXZ45063.1 - 0.098 12.7 0.8 0.18 11.8 0.8 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KXZ45063.1 - 0.11 13.0 0.0 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXZ45063.1 - 0.14 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1467 PF07330.12 KXZ45065.1 - 0.036 14.0 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) adh_short PF00106.25 KXZ45067.1 - 1.2e-27 96.7 0.0 1.5e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ45067.1 - 2.5e-13 50.1 0.0 5.1e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ45067.1 - 4.6e-05 23.4 0.0 8.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXZ45067.1 - 0.024 14.1 0.0 0.073 12.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SET PF00856.28 KXZ45071.1 - 6.9e-07 29.8 0.0 3e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 SET domain Calmodulin_bind PF07887.11 KXZ45073.1 - 2.2e-06 27.2 0.0 4.3e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Calmodulin binding protein-like DUF1003 PF06210.11 KXZ45073.1 - 0.077 13.1 2.7 0.19 11.8 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Ribosomal_L31 PF01197.18 KXZ45075.1 - 1e-16 60.9 0.3 1.6e-16 60.2 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L31 DnaJ_CXXCXGXG PF00684.19 KXZ45076.1 - 0.2 12.1 0.2 0.2 12.1 0.2 2.6 3 0 0 3 3 3 0 DnaJ central domain FixH PF05751.11 KXZ45077.1 - 0.064 13.3 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 FixH Mito_fiss_reg PF05308.11 KXZ45079.1 - 0.9 9.6 2.7 2.5 8.1 2.7 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator GATase_5 PF13507.6 KXZ45081.1 - 3.6e-40 137.7 0.0 5.7e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KXZ45081.1 - 3.8e-22 79.1 0.0 5.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain MPM1 PF17234.2 KXZ45081.1 - 0.27 11.5 0.0 0.43 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 ADP_ribosyl_GH PF03747.14 KXZ45083.1 - 8.9e-07 28.9 0.2 9.1e-07 28.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MAPEG PF01124.18 KXZ45083.1 - 0.025 14.5 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 MAPEG family RVT_1 PF00078.27 KXZ45084.1 - 0.039 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 KXZ45085.1 - 7.6e-18 64.7 0.0 1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ45085.1 - 4.1e-10 39.5 0.0 7.4e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain DUF3138 PF11336.8 KXZ45085.1 - 2.4 6.7 6.9 3.7 6.1 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TMF_TATA_bd PF12325.8 KXZ45087.1 - 3.4e-11 43.4 0.3 3.4e-11 43.4 0.3 6.6 3 1 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXZ45087.1 - 2.6e-08 33.7 7.0 2.6e-08 33.7 7.0 8.4 8 2 1 9 9 8 1 TATA element modulatory factor 1 DNA binding FUSC PF04632.12 KXZ45087.1 - 0.00035 19.2 5.1 0.00035 19.2 5.1 4.1 2 1 2 4 4 3 1 Fusaric acid resistance protein family HOOK PF05622.12 KXZ45087.1 - 0.0006 18.1 14.1 0.0006 18.1 14.1 4.9 3 2 2 5 5 5 3 HOOK protein DUF4763 PF15960.5 KXZ45087.1 - 0.00097 18.5 2.7 0.00097 18.5 2.7 4.4 4 1 2 6 6 6 1 Domain of unknown function (DUF4763) Cep57_CLD_2 PF14197.6 KXZ45087.1 - 0.0014 18.7 7.7 0.0014 18.7 7.7 8.0 7 3 2 9 9 8 2 Centrosome localisation domain of PPC89 FlxA PF14282.6 KXZ45087.1 - 0.0023 17.9 2.3 0.0023 17.9 2.3 6.1 4 1 2 6 6 6 3 FlxA-like protein DUF4686 PF15742.5 KXZ45087.1 - 0.0046 16.2 41.7 0.017 14.3 4.1 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4686) Filament PF00038.21 KXZ45087.1 - 0.0046 16.6 9.9 0.0046 16.6 9.9 5.3 2 1 3 5 5 5 3 Intermediate filament protein DUF1664 PF07889.12 KXZ45087.1 - 0.026 14.6 23.9 0.14 12.2 0.4 6.1 4 1 3 7 7 7 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 KXZ45087.1 - 0.028 15.3 8.3 0.028 15.3 8.3 5.4 4 2 1 5 5 5 0 cGMP-dependent protein kinase interacting domain HMMR_N PF15905.5 KXZ45087.1 - 0.23 10.9 48.4 0.67 9.4 4.1 5.4 3 1 1 5 5 5 0 Hyaluronan mediated motility receptor N-terminal TSC22 PF01166.18 KXZ45087.1 - 0.75 10.2 15.6 21 5.5 0.4 6.2 5 1 1 6 6 6 0 TSC-22/dip/bun family HAP1_N PF04849.13 KXZ45087.1 - 0.82 8.8 51.9 0.024 13.9 17.0 4.8 3 2 1 4 4 4 0 HAP1 N-terminal conserved region Taxilin PF09728.9 KXZ45087.1 - 0.96 8.6 47.1 0.19 10.9 16.4 4.6 2 1 2 4 4 3 0 Myosin-like coiled-coil protein Fib_alpha PF08702.10 KXZ45087.1 - 0.97 9.6 17.1 2.6 8.2 0.3 4.9 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 KXZ45087.1 - 1.7 8.6 6.9 2.1 8.3 0.2 4.0 2 1 1 4 4 4 0 Apolipoprotein O DUF1515 PF07439.11 KXZ45087.1 - 2.5 8.2 34.9 0.95 9.5 1.9 6.5 5 2 1 6 6 6 0 Protein of unknown function (DUF1515) SHE3 PF17078.5 KXZ45087.1 - 7.2 6.2 23.4 10 5.7 4.4 4.4 2 1 2 4 4 4 0 SWI5-dependent HO expression protein 3 Jnk-SapK_ap_N PF09744.9 KXZ45087.1 - 10 6.4 62.0 3.6 7.8 9.4 5.8 3 1 2 5 5 5 0 JNK_SAPK-associated protein-1 Fe-S_biosyn PF01521.20 KXZ45088.1 - 1.5e-08 34.8 0.0 1.5e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3675 PF12428.8 KXZ45089.1 - 0.014 15.9 0.0 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) PRIMA1 PF16101.5 KXZ45091.1 - 0.8 9.7 4.0 1.4 9.0 4.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXZ45091.1 - 0.95 8.9 12.8 1.4 8.3 12.8 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal BTB PF00651.31 KXZ45093.1 - 1.2e-09 38.4 0.0 6.6e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KXZ45093.1 - 2.1e-05 24.6 0.0 4.8e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF1631 PF07793.11 KXZ45093.1 - 0.5 8.7 5.9 0.69 8.3 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1295 PF06966.12 KXZ45094.1 - 8.1e-67 225.2 1.7 9.8e-67 224.9 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXZ45094.1 - 0.00019 21.7 0.1 0.0012 19.2 0.1 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KXZ45094.1 - 0.00032 20.7 0.2 0.00067 19.7 0.2 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KXZ45094.1 - 0.01 16.2 3.5 0.011 16.1 0.0 2.8 3 0 0 3 3 3 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KXZ45094.1 - 0.28 9.9 2.6 0.41 9.3 0.5 2.1 2 1 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family PNISR PF15996.5 KXZ45095.1 - 0.19 12.0 8.6 0.25 11.6 8.6 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR BUD22 PF09073.10 KXZ45095.1 - 7.8 5.7 24.9 9.4 5.5 24.9 1.1 1 0 0 1 1 1 0 BUD22 RRP36 PF06102.12 KXZ45096.1 - 3.3e-36 124.8 15.9 3.9e-36 124.5 15.9 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF4391 PF14335.6 KXZ45096.1 - 0.0084 15.8 0.8 0.01 15.6 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4391) DUF1151 PF06625.11 KXZ45096.1 - 0.078 12.9 14.3 0.035 14.1 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) zf-MYND PF01753.18 KXZ45097.1 - 9e-05 22.5 9.2 0.00018 21.5 9.2 1.5 1 0 0 1 1 1 1 MYND finger COQ7 PF03232.13 KXZ45099.1 - 3.3e-05 23.7 1.4 0.00023 21.0 0.0 2.3 3 0 0 3 3 3 1 Ubiquinone biosynthesis protein COQ7 TPR_12 PF13424.6 KXZ45100.1 - 1.3e-61 204.9 24.8 3.9e-16 59.1 1.6 6.9 2 1 4 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ45100.1 - 1.8e-34 116.6 25.7 2.7e-09 36.6 0.1 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ45100.1 - 5.6e-11 41.7 14.9 0.071 13.3 0.1 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ45100.1 - 3.3e-10 39.3 10.4 0.094 12.6 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ45100.1 - 2.3e-09 36.6 6.5 0.14 12.2 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45100.1 - 8.5e-05 22.5 0.4 3.2 8.2 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.7 KXZ45100.1 - 0.00086 19.5 7.9 0.021 15.1 0.1 4.0 3 1 1 4 4 4 2 Tetratrico peptide repeat TPR_16 PF13432.6 KXZ45100.1 - 0.00099 19.7 40.6 0.4 11.4 0.0 8.8 9 1 2 11 11 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ45100.1 - 0.041 14.4 22.3 0.13 12.8 0.1 6.0 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ45100.1 - 0.05 13.3 0.3 28 4.5 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 KXZ45100.1 - 0.16 12.4 3.2 0.72 10.4 0.0 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat CheZ PF04344.13 KXZ45100.1 - 0.27 11.1 1.1 7.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ TPR_6 PF13174.6 KXZ45100.1 - 2.3 9.1 14.1 15 6.4 0.1 6.7 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF4770 PF15994.5 KXZ45101.1 - 0.0015 18.8 6.1 0.0017 18.7 6.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) TP53IP5 PF15331.6 KXZ45101.1 - 0.007 16.5 8.9 0.0078 16.4 8.9 1.0 1 0 0 1 1 1 1 Cellular tumour antigen p53-inducible 5 CDC45 PF02724.14 KXZ45101.1 - 0.0073 14.7 2.0 0.0085 14.4 2.0 1.0 1 0 0 1 1 1 1 CDC45-like protein PTPRCAP PF15713.5 KXZ45101.1 - 0.0094 16.2 2.3 0.011 16.0 2.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated US22 PF02393.16 KXZ45101.1 - 0.019 15.2 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 US22 like Presenilin PF01080.17 KXZ45101.1 - 0.03 13.1 3.6 0.03 13.1 3.6 1.0 1 0 0 1 1 1 0 Presenilin CSG2 PF16965.5 KXZ45101.1 - 0.067 12.1 1.5 0.074 12.0 1.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Pap_E4 PF02711.14 KXZ45101.1 - 0.084 13.8 8.3 0.1 13.6 8.3 1.1 1 0 0 1 1 1 0 E4 protein CLN3 PF02487.17 KXZ45101.1 - 0.1 11.6 2.1 0.1 11.6 2.1 1.0 1 0 0 1 1 1 0 CLN3 protein FAM176 PF14851.6 KXZ45101.1 - 0.15 11.7 2.5 0.18 11.5 2.5 1.2 1 0 0 1 1 1 0 FAM176 family RNA_pol_Rpc4 PF05132.14 KXZ45101.1 - 0.23 11.9 14.5 0.27 11.7 14.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 KXZ45101.1 - 0.25 10.5 0.8 0.25 10.5 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter OATP PF03137.20 KXZ45101.1 - 0.27 9.5 5.0 0.29 9.3 5.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4834 PF16118.5 KXZ45101.1 - 0.4 11.7 7.7 0.49 11.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EOS1 PF12326.8 KXZ45101.1 - 0.63 9.9 2.5 0.67 9.9 2.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein RR_TM4-6 PF06459.12 KXZ45101.1 - 1.1 9.0 12.9 1.3 8.8 12.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCM_bind PF09739.9 KXZ45101.1 - 1.2 7.5 12.2 1.3 7.4 12.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor TMEM214 PF10151.9 KXZ45101.1 - 1.6 7.1 13.2 1.8 7.0 13.2 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator FPN1 PF06963.12 KXZ45101.1 - 1.9 7.0 2.9 2.1 6.8 2.9 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Connexin PF00029.19 KXZ45101.1 - 3.5 7.3 10.1 4.2 7.1 10.1 1.1 1 0 0 1 1 1 0 Connexin POPLD PF08170.12 KXZ45101.1 - 6.8 7.1 6.7 12 6.3 6.7 1.5 1 1 0 1 1 1 0 POPLD (NUC188) domain DAO PF01266.24 KXZ45102.1 - 4e-17 62.8 9.4 1.9e-13 50.8 3.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXZ45102.1 - 1e-07 31.5 0.2 1.7e-07 30.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXZ45102.1 - 5.1e-06 25.8 1.6 5.1e-06 25.8 1.6 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXZ45102.1 - 5.7e-06 26.5 1.5 5.7e-06 26.5 1.5 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ45102.1 - 0.00024 20.4 0.6 0.00036 19.9 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXZ45102.1 - 0.002 17.3 0.3 0.0027 16.8 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXZ45102.1 - 0.0034 16.2 0.6 0.0053 15.5 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KXZ45102.1 - 0.0044 16.1 0.6 0.0076 15.3 0.6 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KXZ45102.1 - 0.0051 16.2 4.9 0.0072 15.7 4.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXZ45102.1 - 0.0074 15.6 2.3 0.0076 15.5 1.2 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXZ45102.1 - 0.05 12.9 0.1 0.071 12.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ45102.1 - 0.2 12.2 0.9 0.47 11.0 0.9 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXZ45102.1 - 0.79 9.6 2.5 0.38 10.6 0.4 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAD_porph PF04371.15 KXZ45103.1 - 8.5e-33 114.0 0.0 9.8e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 KXZ45103.1 - 0.032 13.3 0.0 0.067 12.3 0.0 1.7 1 1 0 1 1 1 0 Amidinotransferase BRE PF06113.12 KXZ45104.1 - 1.2e-17 63.8 0.0 1e-09 37.7 0.0 2.4 2 1 0 2 2 2 2 Brain and reproductive organ-expressed protein (BRE) Transglut_core PF01841.19 KXZ45105.1 - 7.7e-07 29.5 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Acid_PPase PF12689.7 KXZ45106.1 - 3.4e-56 189.7 0.0 3.8e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 KXZ45106.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4214 PF13946.6 KXZ45107.1 - 0.00069 19.6 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4214) GNT-I PF03071.15 KXZ45107.1 - 0.0018 17.2 0.1 0.0052 15.6 0.1 1.7 1 1 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 KXZ45107.1 - 0.0058 16.5 0.1 0.0092 15.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MGAT2 PF05060.14 KXZ45107.1 - 0.075 12.1 0.1 2.9 6.9 0.0 2.1 1 1 1 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) GNT-I PF03071.15 KXZ45108.1 - 0.0016 17.3 0.1 0.0079 15.0 0.1 1.9 1 1 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 KXZ45108.1 - 0.002 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MGAT2 PF05060.14 KXZ45108.1 - 0.014 14.5 0.0 0.029 13.4 0.0 1.5 1 1 1 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) Glycos_transf_2 PF00535.26 KXZ45108.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 KXZ45109.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 ThiF PF00899.21 KXZ45110.1 - 1.5e-51 175.1 0.3 1.9e-51 174.8 0.3 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KXZ45110.1 - 0.012 15.8 2.4 0.073 13.3 2.4 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KXZ45110.1 - 0.034 13.8 0.2 0.048 13.3 0.2 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KXZ45110.1 - 0.083 12.5 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KXZ45111.1 - 5.8e-16 59.1 0.0 7.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXZ45112.1 - 8e-12 45.5 0.2 1.2e-11 44.9 0.2 1.3 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPG_MGDP_dh PF00984.19 KXZ45112.1 - 0.17 12.1 0.0 0.97 9.7 0.0 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain EF-hand_1 PF00036.32 KXZ45113.1 - 0.00013 21.3 0.0 0.00029 20.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ45113.1 - 0.0058 16.1 0.1 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ45113.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 KXZ45113.1 - 0.023 15.1 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF3464 PF11947.8 KXZ45113.1 - 0.04 13.7 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EF-hand_6 PF13405.6 KXZ45113.1 - 0.059 13.3 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Spc29 PF17082.5 KXZ45114.1 - 0.0079 16.1 0.5 0.0079 16.1 0.5 2.3 2 1 1 3 3 3 1 Spindle Pole Component 29 End3 PF12761.7 KXZ45114.1 - 0.012 15.8 13.8 0.085 13.0 12.1 2.9 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 FAM76 PF16046.5 KXZ45114.1 - 0.12 11.7 10.2 0.027 13.8 6.4 1.8 2 0 0 2 2 2 0 FAM76 protein AAA_13 PF13166.6 KXZ45114.1 - 0.71 8.4 10.0 1.1 7.8 10.0 1.2 1 0 0 1 1 1 0 AAA domain Pox_A_type_inc PF04508.12 KXZ45114.1 - 0.98 9.4 10.0 31 4.6 0.2 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF4407 PF14362.6 KXZ45114.1 - 1.8 7.8 35.9 1 8.7 21.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) FlxA PF14282.6 KXZ45114.1 - 2.2 8.3 19.5 1.2e+02 2.8 16.6 3.3 2 1 0 2 2 2 0 FlxA-like protein DUF16 PF01519.16 KXZ45114.1 - 4.4 7.8 7.4 30 5.2 1.0 3.0 1 1 0 2 2 2 0 Protein of unknown function DUF16 YabA PF06156.13 KXZ45114.1 - 4.7 7.9 13.0 25 5.6 0.3 4.3 2 2 1 4 4 4 0 Initiation control protein YabA Fez1 PF06818.15 KXZ45114.1 - 7.1 7.0 23.0 0.45 10.9 13.0 3.1 3 0 0 3 3 3 0 Fez1 CHD5 PF04420.14 KXZ45114.1 - 7.1 6.5 6.1 23 4.8 5.7 2.2 1 1 0 1 1 1 0 CHD5-like protein V_ATPase_I PF01496.19 KXZ45114.1 - 7.4 4.3 5.7 4.7 5.0 3.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family peroxidase PF00141.23 KXZ45115.1 - 7e-53 179.7 0.0 1.1e-52 179.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase EF-hand_1 PF00036.32 KXZ45117.1 - 0.0007 19.0 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ45117.1 - 0.0008 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ45117.1 - 0.018 15.5 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KXZ45117.1 - 0.021 14.3 0.1 0.044 13.3 0.1 1.5 1 0 0 1 1 1 0 EF hand Tmemb_170 PF10190.9 KXZ45117.1 - 0.055 13.8 4.2 2.2 8.7 0.3 2.5 2 0 0 2 2 2 0 Putative transmembrane protein 170 EF-hand_8 PF13833.6 KXZ45117.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair VOMI PF03762.17 KXZ45119.1 - 0.00027 21.1 0.2 0.0016 18.6 0.2 1.9 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) VOMI PF03762.17 KXZ45120.1 - 1.2e-18 67.8 0.3 1.9e-18 67.2 0.3 1.3 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) RicinB_lectin_2 PF14200.6 KXZ45120.1 - 1e-15 58.2 0.0 2e-11 44.5 0.0 2.8 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ45120.1 - 6.4e-13 49.1 0.0 5.3e-07 29.9 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KXZ45120.1 - 0.00011 21.8 0.4 0.00059 19.5 0.1 2.0 1 1 1 2 2 2 1 Cytolethal distending toxin A/C domain FadA PF09403.10 KXZ45121.1 - 0.0033 17.9 0.2 0.0038 17.7 0.2 1.2 1 0 0 1 1 1 1 Adhesion protein FadA DUF5638 PF18688.1 KXZ45121.1 - 0.02 15.2 1.6 0.37 11.1 0.6 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5638) DUF5344 PF17279.2 KXZ45121.1 - 0.022 15.3 0.3 0.035 14.7 0.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5344) VP9 PF09625.10 KXZ45121.1 - 0.038 14.1 4.2 1.9 8.7 0.8 2.4 1 1 1 2 2 2 0 VP9 protein DUF5082 PF16888.5 KXZ45121.1 - 0.044 14.1 0.4 0.046 14.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF1320 PF07030.12 KXZ45121.1 - 0.052 13.7 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Fib_alpha PF08702.10 KXZ45121.1 - 0.15 12.3 0.2 0.16 12.1 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Piezo_RRas_bdg PF12166.8 KXZ45122.1 - 7.6e-33 114.4 0.0 3e-29 102.6 0.2 2.0 2 0 0 2 2 2 2 Piezo non-specific cation channel, R-Ras-binding domain Phage_holin_2_1 PF04971.12 KXZ45123.1 - 0.085 12.9 1.0 0.45 10.5 1.0 2.3 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF4400 PF14348.6 KXZ45123.1 - 1.1 8.7 7.4 4.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Erythro_esteras PF05139.14 KXZ45125.1 - 8.1e-30 104.8 0.1 3e-20 73.3 0.0 2.7 1 1 2 3 3 3 2 Erythromycin esterase DUF2587 PF10759.9 KXZ45125.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF4179 PF13786.6 KXZ45127.1 - 0.13 12.8 2.4 0.18 12.3 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Phage_holin_7_1 PF16081.5 KXZ45127.1 - 0.45 10.7 10.6 0.5 10.5 10.6 1.1 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family RskA PF10099.9 KXZ45127.1 - 2 8.7 14.6 2 8.7 14.6 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Rad60-SLD PF11976.8 KXZ45128.1 - 6.9e-06 25.8 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Pkinase_Tyr PF07714.17 KXZ45129.1 - 1.1e-36 126.5 0.0 3.6e-31 108.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ45129.1 - 4.5e-34 118.0 0.0 4e-26 91.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain GAF PF01590.26 KXZ45129.1 - 5.3e-09 36.8 0.0 1.9e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KXZ45129.1 - 8.6e-06 26.1 0.0 2.7e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase_fungal PF17667.1 KXZ45129.1 - 0.00056 18.8 0.0 0.0011 17.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXZ45129.1 - 0.017 14.5 0.1 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ45129.1 - 0.3 10.7 0.2 1.2 8.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Peptidase_M1 PF01433.20 KXZ45131.1 - 2.4e-25 89.4 0.0 3.5e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXZ45131.1 - 5.3e-22 78.9 0.0 1e-20 74.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain zf-MYND PF01753.18 KXZ45133.1 - 6.7e-08 32.5 12.1 1.5e-07 31.4 12.1 1.6 1 0 0 1 1 1 1 MYND finger SprT-like PF10263.9 KXZ45134.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 SprT-like family EF-hand_1 PF00036.32 KXZ45135.1 - 4.4e-07 29.0 0.0 9.7e-07 27.9 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ45135.1 - 2e-05 24.9 0.0 5.7e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ45135.1 - 2.3e-05 24.0 0.1 6.1e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KXZ45135.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ45135.1 - 0.00032 20.5 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair SAM_2 PF07647.17 KXZ45135.1 - 0.035 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) EF-hand_4 PF12763.7 KXZ45135.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Cu_amine_oxid PF01179.20 KXZ45137.1 - 7.8e-61 206.2 0.0 8.7e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.20 KXZ45138.1 - 4.5e-57 193.8 0.0 5.6e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXZ45138.1 - 5.1e-11 42.7 0.0 9.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXZ45138.1 - 1.6e-09 38.1 0.0 3.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain RicinB_lectin_2 PF14200.6 KXZ45139.1 - 3.1e-36 123.9 21.4 2.5e-08 34.5 0.0 11.6 9 3 3 12 12 12 7 Ricin-type beta-trefoil lectin domain-like HYR PF02494.16 KXZ45139.1 - 8.6e-33 112.5 57.0 6e-07 29.7 0.2 10.6 9 1 1 10 10 10 8 HYR domain Ricin_B_lectin PF00652.22 KXZ45139.1 - 2.7e-32 111.7 35.5 3.1e-13 50.1 0.0 11.7 9 4 2 11 11 11 5 Ricin-type beta-trefoil lectin domain WSC PF01822.19 KXZ45139.1 - 1.6e-29 101.9 16.0 3.3e-15 56.0 0.6 12.5 13 0 0 13 13 13 4 WSC domain VCBS PF13517.6 KXZ45139.1 - 1.2e-18 67.4 48.4 0.00029 21.4 0.4 13.2 12 2 1 13 13 13 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CDtoxinA PF03498.14 KXZ45139.1 - 4.1e-06 26.5 7.9 0.06 12.9 0.2 5.5 4 1 1 5 5 5 2 Cytolethal distending toxin A/C domain DUF3992 PF13157.6 KXZ45139.1 - 1.1 10.1 6.5 41 5.0 1.6 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3992) zf-MYND PF01753.18 KXZ45140.1 - 5e-07 29.7 9.6 1.1e-06 28.6 9.6 1.6 1 0 0 1 1 1 1 MYND finger TTL PF03133.15 KXZ45141.1 - 1.8e-68 230.8 0.0 1.3e-48 165.7 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ45141.1 - 0.00075 18.8 0.1 0.057 12.6 0.0 2.7 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ45141.1 - 0.018 14.3 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp EF-hand_1 PF00036.32 KXZ45142.1 - 0.00024 20.5 0.0 0.00052 19.4 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ45142.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KXZ45142.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ45142.1 - 0.09 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain TTL PF03133.15 KXZ45143.1 - 7.7e-30 104.0 0.1 9.5e-25 87.3 0.0 2.4 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family Guanylate_cyc PF00211.20 KXZ45145.1 - 3e-08 33.5 0.0 6.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF5134 PF17197.4 KXZ45147.1 - 0.049 13.5 2.0 0.054 13.4 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) DUF202 PF02656.15 KXZ45147.1 - 0.5 10.9 6.0 0.27 11.7 3.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) VTC PF09359.10 KXZ45148.1 - 7.8e-75 251.8 1.7 1.1e-74 251.2 0.0 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 KXZ45148.1 - 1.3e-18 68.1 20.4 3.4e-11 43.7 1.7 3.5 1 1 2 3 3 3 3 SPX domain DUF202 PF02656.15 KXZ45148.1 - 1.8e-12 47.5 2.1 1.8e-12 47.5 2.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Oxidored_q2 PF00420.24 KXZ45149.1 - 3.1e-14 52.5 10.1 4.6e-14 51.9 10.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF3704 PF12488.8 KXZ45149.1 - 0.1 12.3 0.7 0.1 12.3 0.7 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3704) DUF2521 PF10730.9 KXZ45153.1 - 0.0089 16.1 0.2 0.01 15.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2521) 5-FTHF_cyc-lig PF01812.20 KXZ45154.1 - 9e-07 28.9 0.0 1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Isochorismatase PF00857.20 KXZ45155.1 - 2.3e-31 109.3 0.0 2.8e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Hydrolase_3 PF08282.12 KXZ45156.1 - 3.8e-36 125.2 0.0 5.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0054 PF02130.17 KXZ45156.1 - 4.7e-32 110.5 0.0 6.6e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 S6PP PF05116.13 KXZ45156.1 - 1.1e-09 38.2 0.0 8.3e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KXZ45156.1 - 0.00064 20.1 11.4 0.37 11.0 7.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase GcrA PF07750.11 KXZ45158.1 - 0.19 12.1 0.1 0.32 11.4 0.1 1.3 1 0 0 1 1 1 0 GcrA cell cycle regulator 5_nucleotid_C PF02872.18 KXZ45159.1 - 2.1e-66 223.0 0.0 2e-33 115.8 0.0 2.3 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain PhoD_N PF16655.5 KXZ45159.1 - 7.4e-11 42.4 0.0 1.7e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain DUF3707 PF12499.8 KXZ45159.1 - 1.3e-09 38.7 0.5 2.8e-09 37.7 0.5 1.5 1 0 0 1 1 1 1 Pherophorin Pur_ac_phosph_N PF16656.5 KXZ45159.1 - 7.4e-05 23.2 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Helicase_C PF00271.31 KXZ45161.1 - 2.4e-11 44.0 0.0 7.7e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ45161.1 - 2.5e-08 33.9 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ45161.1 - 8.4e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VWA PF00092.28 KXZ45162.1 - 3.4e-06 27.4 0.0 8.1e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXZ45162.1 - 0.00016 22.3 0.0 0.00065 20.3 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain GBP PF02263.19 KXZ45162.1 - 0.00058 19.2 0.1 0.0015 17.8 0.0 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KXZ45162.1 - 0.0018 16.5 0.0 0.0026 16.0 0.0 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) VWA_3 PF13768.6 KXZ45162.1 - 0.0024 17.8 0.0 0.0066 16.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3632 PF12311.8 KXZ45162.1 - 0.069 13.6 0.8 0.98 9.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3632) FKBP_C PF00254.28 KXZ45163.1 - 4.1e-70 232.2 0.6 1.8e-33 114.7 0.0 3.3 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KXZ45163.1 - 3.9e-11 42.3 7.4 0.00071 19.3 1.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ45163.1 - 6.6e-11 41.5 5.8 0.0029 17.6 1.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KXZ45163.1 - 2.4e-05 24.4 0.0 0.0011 19.0 0.0 3.1 3 1 0 3 3 3 1 BDBT FKBP like N-terminal TPR_9 PF13371.6 KXZ45163.1 - 0.00037 20.6 2.2 0.0013 18.8 0.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ45163.1 - 0.0028 17.3 4.4 1.1 9.0 0.0 3.1 3 0 0 3 3 3 2 TPR repeat Fis1_TPR_C PF14853.6 KXZ45163.1 - 0.0042 17.1 3.4 0.49 10.5 0.5 3.4 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KXZ45163.1 - 0.0049 17.1 2.9 0.7 10.2 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ45163.1 - 0.0051 17.3 3.9 0.044 14.3 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ45163.1 - 0.0097 16.5 2.9 1.4 9.6 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45163.1 - 0.049 13.8 2.4 12 6.4 0.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ45163.1 - 0.32 11.5 6.3 12 6.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ45163.1 - 0.42 11.6 2.0 47 5.2 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 KXZ45164.1 - 2.1e-13 50.8 0.1 3.8e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ45164.1 - 3.6e-10 39.8 0.0 5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KXZ45164.1 - 6.3e-10 39.1 0.0 1.1e-09 38.3 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KXZ45164.1 - 2.2e-09 37.3 0.0 3.5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ45164.1 - 1.8e-08 34.9 0.1 4.8e-08 33.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ45164.1 - 3.2e-08 34.2 0.0 5.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ45164.1 - 8.1e-06 25.5 0.1 1.4e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KXZ45164.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_PK PF05891.12 KXZ45164.1 - 0.019 14.5 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_24 PF13578.6 KXZ45164.1 - 0.065 14.3 0.1 0.12 13.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 KXZ45165.1 - 0.0023 18.5 2.2 1.4 9.5 0.0 4.6 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) LRR_4 PF12799.7 KXZ45165.1 - 0.23 11.9 0.7 14 6.3 0.1 3.6 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) AAA_28 PF13521.6 KXZ45168.1 - 0.0003 21.1 0.0 0.00052 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ45168.1 - 0.00035 21.1 0.0 0.00072 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXZ45168.1 - 0.00073 19.1 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KXZ45168.1 - 0.0011 19.2 0.0 0.0043 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 KXZ45168.1 - 0.0055 17.0 0.1 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 KXZ45168.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.18 KXZ45168.1 - 0.24 10.7 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF768 PF05589.11 KXZ45171.1 - 0.061 13.3 0.1 0.061 13.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF768) G-patch PF01585.23 KXZ45172.1 - 1.5e-15 56.7 3.6 4.5e-15 55.3 3.6 1.9 1 1 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KXZ45172.1 - 9.9e-07 28.9 2.7 1.5e-06 28.3 2.7 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 KXZ45172.1 - 1e-06 28.7 0.5 1e-06 28.7 0.5 2.3 3 0 0 3 3 2 1 G-patch domain zf-met PF12874.7 KXZ45172.1 - 0.00018 21.8 0.4 0.00029 21.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXZ45172.1 - 0.0049 17.2 1.4 0.0075 16.6 1.4 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Fringe PF02434.16 KXZ45172.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Fringe-like zf-C2H2 PF00096.26 KXZ45172.1 - 0.026 15.0 0.8 0.042 14.3 0.8 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.12 KXZ45172.1 - 0.029 14.5 3.7 0.048 13.8 3.7 1.3 1 0 0 1 1 1 0 DBF zinc finger AKAP95 PF04988.12 KXZ45172.1 - 0.052 13.8 3.0 0.073 13.3 3.0 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 KXZ45172.1 - 0.072 14.0 0.1 0.14 13.1 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Apolipoprotein PF01442.18 KXZ45172.1 - 0.73 9.7 17.9 1 9.2 17.9 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TMCO5 PF14992.6 KXZ45172.1 - 1.8 8.1 8.4 2.5 7.6 8.4 1.1 1 0 0 1 1 1 0 TMCO5 family Presenilin PF01080.17 KXZ45172.1 - 8.7 5.0 7.8 4.9 5.8 5.5 1.6 1 1 1 2 2 2 0 Presenilin DNA_pol_phi PF04931.13 KXZ45173.1 - 0.81 7.7 2.3 1.1 7.3 2.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rod_cone_degen PF15201.6 KXZ45173.1 - 2.8 8.1 7.2 0.18 12.0 0.9 2.4 3 0 0 3 3 3 0 Progressive rod-cone degeneration Fe_hyd_lg_C PF02906.14 KXZ45175.1 - 1.2e-59 201.9 0.0 2.5e-59 200.9 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KXZ45175.1 - 9.3e-10 38.4 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Iron hydrogenase small subunit SSP160 PF06933.11 KXZ45176.1 - 1.4 7.0 8.7 2.3 6.3 8.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ABC_membrane PF00664.23 KXZ45177.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region K_channel_TID PF07941.11 KXZ45178.1 - 0.00027 21.3 8.9 0.00027 21.3 8.9 3.9 3 1 1 4 4 4 1 Potassium channel Kv1.4 tandem inactivation domain Abhydrolase_6 PF12697.7 KXZ45178.1 - 0.00066 20.3 26.2 0.0016 19.1 26.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ45178.1 - 0.003 17.2 1.4 0.0033 17.1 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ45178.1 - 0.0032 16.8 0.2 0.0066 15.7 0.2 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXZ45178.1 - 0.0035 17.0 0.6 0.067 12.8 0.3 2.3 2 1 0 2 2 2 1 Putative esterase PGAP1 PF07819.13 KXZ45178.1 - 0.029 14.1 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein GRP PF07172.11 KXZ45178.1 - 2.8 8.7 20.1 0.16 12.6 7.7 2.9 3 0 0 3 3 3 0 Glycine rich protein family PP2C PF00481.21 KXZ45179.1 - 2.3e-22 79.8 0.0 8.6e-21 74.7 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXZ45179.1 - 0.00024 20.8 0.2 0.00024 20.8 0.2 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KXZ45179.1 - 0.018 14.9 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) AP3D1 PF06375.11 KXZ45179.1 - 0.6 10.3 4.5 3.5 7.9 0.9 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Lipase_GDSL_2 PF13472.6 KXZ45181.1 - 1.1e-09 39.0 0.7 2.2e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXZ45181.1 - 1.5e-05 25.1 0.1 0.041 13.8 0.0 2.1 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXZ45182.1 - 1.8e-16 61.0 0.0 2.1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXZ45182.1 - 0.055 13.4 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Methyltransf_11 PF08241.12 KXZ45183.1 - 4.3e-15 56.1 0.0 1.1e-13 51.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ45183.1 - 1e-12 48.6 0.0 7.8e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ45183.1 - 8.5e-07 28.9 0.0 2.6e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ45183.1 - 1.1e-06 29.3 0.0 1.9e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ45183.1 - 1.4e-06 27.9 0.0 6.2e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXZ45183.1 - 2.4e-05 23.8 0.0 9.5e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXZ45183.1 - 0.00038 20.3 0.0 0.00094 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXZ45183.1 - 0.0021 19.0 0.0 0.015 16.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KXZ45183.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXZ45183.1 - 0.13 11.8 0.0 0.82 9.1 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase PEP_mutase PF13714.6 KXZ45184.1 - 3.6e-42 144.5 0.1 2e-41 142.0 0.1 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXZ45184.1 - 2.4e-10 39.6 0.1 3.5e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family LRR_8 PF13855.6 KXZ45185.1 - 0.084 12.7 0.9 18 5.2 0.0 4.2 5 0 0 5 5 5 0 Leucine rich repeat TBCC PF07986.12 KXZ45186.1 - 8.3e-24 83.6 0.0 1.2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXZ45186.1 - 4.8e-09 36.7 0.2 1e-08 35.6 0.1 1.6 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain UBX PF00789.20 KXZ45187.1 - 8.1e-14 51.6 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 KXZ45187.1 - 0.0011 19.2 0.1 0.0025 18.0 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like DUF3915 PF13054.6 KXZ45187.1 - 2.4 8.1 4.5 4.5 7.3 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) MIF4G_like_2 PF09090.11 KXZ45187.1 - 9.5 5.6 7.7 14 5.1 7.7 1.1 1 0 0 1 1 1 0 MIF4G like CDC45 PF02724.14 KXZ45187.1 - 9.5 4.4 7.5 13 3.9 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein EF-hand_1 PF00036.32 KXZ45188.1 - 4e-17 60.4 0.0 0.00091 18.6 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ45188.1 - 3.2e-13 49.9 0.1 2.7e-06 27.8 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXZ45188.1 - 1.2e-12 46.6 1.7 0.0014 18.4 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KXZ45188.1 - 1.9e-09 37.2 0.0 0.0024 17.7 0.0 3.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KXZ45188.1 - 0.00045 20.5 0.0 2 8.8 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KXZ45188.1 - 0.00098 18.5 2.6 14 5.4 0.0 4.5 5 0 0 5 5 5 2 EF hand IF4E PF01652.18 KXZ45190.1 - 9.1e-52 175.1 0.3 1.1e-51 174.8 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.11 KXZ45190.1 - 0.099 12.8 0.1 2 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1102) EF-hand_7 PF13499.6 KXZ45192.1 - 4.9e-12 46.1 0.0 4.2e-07 30.3 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ45192.1 - 1.6e-11 43.2 0.5 0.00045 19.9 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KXZ45192.1 - 6.4e-11 41.0 0.1 0.0013 18.1 0.0 4.3 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KXZ45192.1 - 1.1e-08 34.8 0.0 0.0061 16.4 0.0 3.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ45192.1 - 2.5e-06 26.7 0.0 5.1e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 KXZ45192.1 - 0.0075 16.6 0.2 0.013 15.8 0.2 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region MRP-L20 PF12824.7 KXZ45193.1 - 0.00015 22.0 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Bot1p PF12298.8 KXZ45193.1 - 0.0074 16.5 0.2 0.019 15.2 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Guanylate_cyc PF00211.20 KXZ45197.1 - 1.3e-08 34.7 0.0 0.00032 20.4 0.1 2.8 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain TFIIA PF03153.13 KXZ45197.1 - 1.5 8.7 9.0 4.2 7.3 9.0 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXZ45197.1 - 6.3 6.3 14.3 9.4 5.8 14.3 1.1 1 0 0 1 1 1 0 Spt20 family SBP_bac_8 PF13416.6 KXZ45198.1 - 1.7e-13 51.0 0.1 3.7e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXZ45198.1 - 9.4e-13 48.8 0.1 9.4e-13 48.8 0.1 2.0 3 0 0 3 3 3 1 Bacterial extracellular solute-binding protein Acyl_transf_3 PF01757.22 KXZ45198.1 - 0.1 11.6 0.2 0.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Acyltransferase family DUF1180 PF06679.12 KXZ45199.1 - 0.0012 19.3 0.4 0.0022 18.4 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF4381 PF14316.6 KXZ45199.1 - 0.011 16.0 0.4 0.023 15.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RWD PF05773.22 KXZ45200.1 - 2.2e-10 40.8 0.0 3.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UPF0029 PF01205.19 KXZ45200.1 - 5.6e-08 33.1 0.0 1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 IATP PF04568.12 KXZ45200.1 - 0.26 11.7 11.0 1.5 9.3 1.5 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Pkinase PF00069.25 KXZ45201.1 - 8e-30 104.1 0.0 9.6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45201.1 - 5.3e-12 45.6 0.0 7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ45201.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ45201.1 - 0.065 12.5 0.0 0.3 10.4 0.0 1.8 1 1 0 1 1 1 0 Kinase-like SAM_decarbox PF01536.16 KXZ45202.1 - 6.4e-90 301.7 0.0 8.3e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase AdoMet_dc PF02675.15 KXZ45202.1 - 0.0031 17.7 0.0 0.0076 16.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase WD40 PF00400.32 KXZ45203.1 - 0.019 15.8 0.1 0.079 13.9 0.0 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat TBCC PF07986.12 KXZ45204.1 - 1.8e-40 137.4 0.8 2.3e-40 137.1 0.8 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KXZ45204.1 - 9e-05 22.1 0.5 0.00019 21.1 0.5 1.6 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Spt4 PF06093.13 KXZ45204.1 - 0.69 10.0 8.6 2 8.5 1.5 2.6 2 1 0 2 2 2 0 Spt4/RpoE2 zinc finger HAD_2 PF13419.6 KXZ45206.1 - 6.3e-15 55.7 0.0 8.9e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ45206.1 - 2e-14 54.4 0.0 8.3e-14 52.4 0.0 2.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ45206.1 - 5.6e-08 32.7 0.0 2.5e-07 30.6 0.0 2.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXZ45206.1 - 0.0039 17.6 0.0 0.056 13.8 0.0 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spt20 PF12090.8 KXZ45206.1 - 0.39 10.3 3.1 0.61 9.7 3.1 1.1 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 KXZ45206.1 - 0.94 9.6 7.2 2.2 8.4 7.2 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 KXZ45207.1 - 1.1e-32 113.5 0.0 2.5e-28 99.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45207.1 - 2.5e-19 69.6 0.0 3.4e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ45207.1 - 0.0026 17.7 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ45207.1 - 0.0049 15.7 0.0 0.0069 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXZ45207.1 - 0.086 11.8 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXZ45207.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ45207.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LOR PF04525.12 KXZ45208.1 - 0.00092 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 LURP-one-related DUF3834 PF12916.7 KXZ45208.1 - 0.088 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) 2OG-FeII_Oxy_3 PF13640.6 KXZ45209.1 - 1.1e-07 32.6 0.0 5.5e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_TAC_11 PF11836.8 KXZ45209.1 - 0.12 12.5 0.9 2.4 8.3 0.0 2.8 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 2OG-FeII_Oxy_3 PF13640.6 KXZ45210.1 - 1.3e-07 32.4 0.0 7.8e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXZ45211.1 - 1.7e-07 32.0 0.0 7.5e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXZ45212.1 - 0.00023 22.0 0.0 0.0014 19.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4719 PF15843.5 KXZ45212.1 - 0.64 10.1 3.5 1.3 9.1 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Pkinase PF00069.25 KXZ45215.1 - 1.8e-20 73.4 0.0 2.2e-12 46.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45215.1 - 5.6e-08 32.4 0.0 0.0059 15.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase ILVD_EDD PF00920.21 KXZ45216.1 - 5e-20 71.6 0.1 6.2e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Dehydratase family AMP_N PF05195.16 KXZ45216.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain ILVD_EDD PF00920.21 KXZ45217.1 - 1.7e-13 50.1 0.1 1.7e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family ILVD_EDD PF00920.21 KXZ45218.1 - 2.2e-108 363.1 0.1 2.6e-108 362.9 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family SRRM_C PF15230.6 KXZ45219.1 - 0.073 13.6 0.3 0.073 13.6 0.3 2.0 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus DUF4864 PF16156.5 KXZ45220.1 - 2e-07 31.6 0.0 1.6e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4864) HMA PF00403.26 KXZ45221.1 - 1.7e-06 28.3 0.0 3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain polyprenyl_synt PF00348.17 KXZ45222.1 - 7.8e-92 306.9 0.0 9.5e-92 306.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CLP_protease PF00574.23 KXZ45222.1 - 0.12 12.3 0.2 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Clp protease Sugarporin_N PF11471.8 KXZ45223.1 - 6.5 6.8 8.4 1.2 9.2 4.5 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension ADH_N PF08240.12 KXZ45224.1 - 2.7e-22 78.7 3.1 4.3e-22 78.0 3.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXZ45224.1 - 7e-22 77.8 0.2 1.9e-21 76.4 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXZ45224.1 - 1.6e-05 24.3 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXZ45224.1 - 9.9e-05 21.7 0.2 0.00022 20.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXZ45224.1 - 0.016 15.1 0.2 0.027 14.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXZ45224.1 - 0.021 15.3 0.0 0.051 14.1 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain ADH_zinc_N_2 PF13602.6 KXZ45224.1 - 0.041 14.9 0.0 0.078 14.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 KXZ45224.1 - 0.041 14.0 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PE PF00934.20 KXZ45224.1 - 0.054 13.8 0.4 0.46 10.8 0.0 2.3 2 0 0 2 2 2 0 PE family adh_short PF00106.25 KXZ45224.1 - 0.14 11.6 0.0 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase ADH_N PF08240.12 KXZ45225.1 - 9.3e-23 80.2 5.0 1.4e-22 79.6 5.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXZ45225.1 - 4.9e-22 78.3 0.5 1.3e-21 77.0 0.1 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXZ45225.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXZ45225.1 - 0.00023 20.5 0.2 0.00051 19.4 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXZ45225.1 - 0.0013 19.8 0.0 0.0028 18.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 KXZ45225.1 - 0.018 14.9 0.2 0.031 14.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXZ45225.1 - 0.018 15.5 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_2 PF03446.15 KXZ45225.1 - 0.055 13.6 0.1 0.093 12.9 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PE PF00934.20 KXZ45225.1 - 0.1 12.9 1.4 0.46 10.8 0.0 2.2 2 0 0 2 2 2 0 PE family Ank_2 PF12796.7 KXZ45226.1 - 2e-10 41.1 0.1 0.0028 18.2 0.0 4.8 4 2 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ45226.1 - 2e-06 28.0 0.6 6.7 7.2 0.0 5.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ45226.1 - 0.00026 21.5 0.8 7.7 7.2 0.0 5.3 5 3 3 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45226.1 - 0.00088 19.6 0.1 80 4.3 0.0 6.3 8 0 0 8 8 8 0 Ankyrin repeat oligo_HPY PF08352.12 KXZ45226.1 - 0.15 12.6 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region Ank PF00023.30 KXZ45226.1 - 1.8 9.1 3.8 1.3e+02 3.3 0.2 4.4 5 1 0 5 5 5 0 Ankyrin repeat VWA_2 PF13519.6 KXZ45227.1 - 0.00028 21.5 0.0 0.00073 20.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXZ45227.1 - 0.00046 19.6 0.9 0.00092 18.7 0.0 2.0 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DHHC PF01529.20 KXZ45228.1 - 8.9e-34 116.5 10.7 8.9e-34 116.5 10.7 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase CbtB PF09489.10 KXZ45228.1 - 0.01 15.9 0.8 0.01 15.9 0.8 2.2 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Guanylate_cyc PF00211.20 KXZ45229.1 - 2.6e-21 76.1 0.0 9.9e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain LRR_8 PF13855.6 KXZ45229.1 - 0.0029 17.3 0.1 0.0057 16.4 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat DUF4577 PF15145.6 KXZ45229.1 - 0.042 13.9 0.2 0.078 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) LRR_4 PF12799.7 KXZ45229.1 - 0.21 12.1 0.0 0.67 10.5 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF2838 PF10998.8 KXZ45233.1 - 0.0035 17.5 0.4 0.0051 17.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Gln-synt_C PF00120.24 KXZ45234.1 - 0.044 12.8 0.1 0.079 11.9 0.0 1.4 2 0 0 2 2 2 0 Glutamine synthetase, catalytic domain CRAL_TRIO PF00650.20 KXZ45235.1 - 2.1e-08 34.0 0.0 3.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain NAD_binding_8 PF13450.6 KXZ45236.1 - 1.8e-10 40.9 4.9 1.1e-09 38.4 4.9 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXZ45236.1 - 3.6e-06 26.5 4.4 0.00051 19.4 1.6 3.1 1 1 2 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXZ45236.1 - 0.00016 20.5 1.0 0.00023 20.0 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KXZ45236.1 - 0.00023 20.6 0.8 0.00031 20.1 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXZ45236.1 - 0.0011 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ45236.1 - 0.0011 19.5 0.6 0.0029 18.1 0.6 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ45236.1 - 0.0027 17.3 3.2 0.0027 17.3 3.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ45236.1 - 0.0069 15.5 2.5 0.012 14.8 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXZ45236.1 - 0.036 14.1 0.5 0.084 12.9 0.3 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KXZ45236.1 - 0.049 12.7 1.2 0.074 12.1 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXZ45236.1 - 0.083 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TGS PF02824.21 KXZ45236.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 TGS domain Pyr_redox_3 PF13738.6 KXZ45236.1 - 0.14 11.3 0.5 0.2 10.9 0.5 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ45236.1 - 0.25 10.6 0.5 0.45 9.7 0.5 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KXZ45236.1 - 2.9 7.1 4.4 4.4 6.6 4.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4281 PF14108.6 KXZ45237.1 - 3.1e-23 82.5 2.3 3.8e-23 82.2 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) Kelch_1 PF01344.25 KXZ45240.1 - 2.9e-31 106.8 14.9 3.7e-13 48.8 0.0 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KXZ45240.1 - 1.2e-19 69.9 14.4 1.2e-08 35.0 0.0 5.8 3 1 2 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KXZ45240.1 - 7.1e-13 48.0 15.9 4.9e-05 23.1 0.0 5.4 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KXZ45240.1 - 9.7e-10 38.3 5.1 0.018 15.0 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ45240.1 - 2.9e-07 30.3 8.0 0.0086 16.1 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 KXZ45240.1 - 1.2e-05 25.5 0.0 1.2e-05 25.5 0.0 6.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Arg_decarbox_C PF17944.1 KXZ45241.1 - 0.051 14.1 0.1 3.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension IL12 PF03039.14 KXZ45241.1 - 0.19 11.0 0.0 7 5.9 0.0 2.1 2 0 0 2 2 2 0 Interleukin-12 alpha subunit RSN1_TM PF13967.6 KXZ45242.1 - 2.7e-25 89.0 0.0 9.2e-17 61.2 0.0 2.1 2 0 0 2 2 2 2 Late exocytosis, associated with Golgi transport Csm1_N PF18504.1 KXZ45243.1 - 0.02 15.2 1.0 0.068 13.5 0.1 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain HalX PF08663.10 KXZ45243.1 - 3.4 8.1 7.7 7.1 7.0 1.2 2.4 2 0 0 2 2 2 0 HalX domain NAD_kinase PF01513.21 KXZ45245.1 - 3.9e-24 85.4 0.0 7.3e-21 74.6 0.0 2.2 1 1 1 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 KXZ45245.1 - 0.02 14.5 0.4 0.047 13.3 0.1 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Phage_holin_3_6 PF07332.11 KXZ45246.1 - 5 7.2 10.3 0.38 10.8 4.4 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ABC_tran PF00005.27 KXZ45248.1 - 1.5e-31 109.7 0.0 2.4e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXZ45248.1 - 3.5e-08 33.1 0.2 4.3e-07 29.6 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 KXZ45248.1 - 2.3e-06 27.5 0.4 0.00014 21.7 0.4 2.5 1 1 1 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.6 KXZ45248.1 - 0.0047 17.3 0.3 0.011 16.2 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXZ45248.1 - 0.007 16.7 0.2 0.04 14.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXZ45248.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin DEAD PF00270.29 KXZ45248.1 - 0.054 13.3 0.2 0.14 11.9 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.17 KXZ45248.1 - 0.14 12.2 0.2 0.26 11.4 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 KXZ45248.1 - 0.18 11.6 2.4 0.2 11.5 0.3 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ank_2 PF12796.7 KXZ45249.1 - 2.5e-07 31.2 0.0 0.017 15.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45249.1 - 1.6e-06 28.6 0.5 0.029 15.0 0.3 4.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ45249.1 - 0.014 15.7 1.1 0.29 11.5 0.0 3.5 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45249.1 - 0.053 14.1 0.0 1.4e+02 3.5 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat DnaJ_C PF01556.18 KXZ45250.1 - 6.5e-22 78.2 0.0 8e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KXZ45250.1 - 1.7e-07 31.5 10.6 2.9e-07 30.7 10.6 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KXZ45250.1 - 0.029 14.5 0.1 0.078 13.1 0.1 1.7 2 0 0 2 2 2 0 DnaJ domain Avian_gp85 PF03708.14 KXZ45250.1 - 0.23 10.7 6.4 0.21 10.8 5.4 1.4 1 1 0 1 1 1 0 Avian retrovirus envelope protein, gp85 mTERF PF02536.14 KXZ45251.1 - 7.9e-08 31.6 0.0 0.013 14.4 0.0 3.1 2 1 0 2 2 2 2 mTERF Ank_4 PF13637.6 KXZ45252.1 - 0.0069 16.9 0.2 46 4.7 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PPR_2 PF13041.6 KXZ45252.1 - 0.048 13.8 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family Ank_4 PF13637.6 KXZ45253.1 - 2.5e-07 31.1 2.3 0.057 14.0 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45253.1 - 1.3e-05 25.7 0.0 0.022 15.3 0.0 3.8 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45254.1 - 9.2e-08 32.5 0.6 0.047 14.3 0.2 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45254.1 - 3.3e-06 27.6 0.0 0.018 15.6 0.0 3.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45254.1 - 0.0046 17.3 0.2 90 4.2 0.0 5.9 8 0 0 8 8 8 0 Ankyrin repeat Ank_4 PF13637.6 KXZ45255.1 - 1.8e-07 31.6 1.0 0.0014 19.1 0.0 3.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45255.1 - 4.4e-05 24.0 0.0 0.0055 17.3 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45255.1 - 0.0049 17.3 0.0 29 5.7 0.0 5.2 7 0 0 7 7 7 1 Ankyrin repeat Amino_oxidase PF01593.24 KXZ45256.1 - 1.7e-49 169.3 0.1 2e-49 169.1 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ45256.1 - 8.6e-15 54.7 0.2 1.9e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ45256.1 - 6e-05 22.4 0.5 0.00048 19.5 0.3 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ45256.1 - 0.00013 21.2 4.5 0.00013 21.2 4.5 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXZ45256.1 - 0.00015 21.1 1.4 0.0003 20.1 1.4 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXZ45256.1 - 0.00022 20.1 1.1 0.00022 20.1 1.1 1.4 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXZ45256.1 - 0.00027 20.6 5.8 0.0012 18.5 5.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXZ45256.1 - 0.0018 17.4 1.8 0.0018 17.4 1.8 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KXZ45256.1 - 0.0027 17.1 3.0 0.0037 16.7 3.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXZ45256.1 - 0.003 16.9 2.0 0.0045 16.3 2.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXZ45256.1 - 0.003 16.7 2.0 0.0045 16.1 2.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXZ45256.1 - 0.011 15.0 1.5 0.016 14.4 1.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXZ45256.1 - 0.049 12.9 0.6 0.083 12.2 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXZ45256.1 - 0.057 14.0 0.9 0.057 14.0 0.9 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXZ45256.1 - 0.28 9.6 0.2 0.43 8.9 0.2 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Peptidase_M20 PF01546.28 KXZ45257.1 - 9.4e-27 94.1 0.2 3.1e-26 92.3 0.2 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXZ45257.1 - 1.5e-08 34.5 0.1 2.9e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Ank_4 PF13637.6 KXZ45258.1 - 2.1e-08 34.6 0.6 0.75 10.5 0.0 5.5 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45258.1 - 2.7e-05 24.7 0.0 1.4 9.5 0.1 3.7 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ45258.1 - 0.0065 16.8 2.7 22 5.5 0.0 5.0 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45258.1 - 0.014 15.9 1.5 82 4.3 0.0 6.3 8 0 0 8 8 8 0 Ankyrin repeat Ank_4 PF13637.6 KXZ45259.1 - 3e-05 24.5 0.2 1.6 9.4 0.0 4.9 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45259.1 - 0.00047 20.7 0.0 1.2 9.8 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45259.1 - 0.015 15.7 0.7 1.9e+02 3.2 0.0 5.6 7 0 0 7 7 7 0 Ankyrin repeat RhlB PF12300.8 KXZ45259.1 - 0.5 10.5 2.5 0.96 9.6 0.3 2.2 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Ank_4 PF13637.6 KXZ45260.1 - 0.00031 21.2 0.2 0.4 11.3 0.0 4.4 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45260.1 - 0.0038 17.8 0.1 0.4 11.3 0.0 3.2 2 1 3 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45260.1 - 0.038 14.5 0.7 1.6e+02 3.4 0.0 5.6 8 0 0 8 8 8 0 Ankyrin repeat Hydrolase PF00702.26 KXZ45261.1 - 6.4e-15 56.0 0.5 1.7e-10 41.5 0.0 2.8 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXZ45261.1 - 1.7e-14 54.3 0.0 1.2e-12 48.3 0.0 2.2 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ45261.1 - 3.9e-10 39.7 0.0 3.5e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KXZ45261.1 - 4e-06 27.4 0.6 1.4e-05 25.6 0.6 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 KXZ45261.1 - 0.02 14.8 0.0 0.13 12.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ45261.1 - 0.027 15.1 0.2 0.069 13.9 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ45261.1 - 0.075 12.8 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Hydrolase_3 PF08282.12 KXZ45261.1 - 0.079 12.7 0.0 6.2 6.5 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Methyltransf_11 PF08241.12 KXZ45261.1 - 0.15 12.7 0.0 0.48 11.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase_6 PF13344.6 KXZ45261.1 - 0.18 11.9 0.0 0.78 9.9 0.0 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Alpha_kinase PF02816.18 KXZ45262.1 - 8e-38 130.4 0.0 1.4e-37 129.6 0.0 1.4 1 1 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KXZ45262.1 - 2.5e-06 28.1 0.0 6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXZ45262.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain rve PF00665.26 KXZ45263.1 - 1.5e-23 83.3 0.0 2.6e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 KXZ45263.1 - 1.9e-15 57.2 0.1 4e-15 56.1 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 KXZ45263.1 - 1.4e-10 40.9 0.0 2.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 KXZ45263.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF716 PF04819.12 KXZ45264.1 - 1.7e-06 27.7 5.8 3.2e-06 26.8 5.8 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF716) DUF3341 PF11821.8 KXZ45264.1 - 0.2 11.3 5.1 0.09 12.4 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Tmemb_170 PF10190.9 KXZ45264.1 - 5.3 7.5 8.9 15 6.0 0.6 3.3 2 1 1 3 3 3 0 Putative transmembrane protein 170 TRM PF02005.16 KXZ45265.1 - 2.2e-108 362.8 0.0 2.7e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KXZ45265.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein SUIM_assoc PF16619.5 KXZ45265.1 - 0.15 12.2 5.7 0.34 11.0 5.7 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Abhydrolase_1 PF00561.20 KXZ45266.1 - 5.3e-06 26.3 0.1 0.00025 20.8 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ45266.1 - 0.00046 20.9 15.6 0.00046 20.9 15.6 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ45266.1 - 0.0032 16.8 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXZ45266.1 - 0.0036 17.1 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein baeRF_family10 PF18854.1 KXZ45266.1 - 0.013 15.7 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 LCAT PF02450.15 KXZ45266.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KXZ45266.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Myelin_MBP PF01669.17 KXZ45266.1 - 0.18 12.4 0.2 0.29 11.7 0.2 1.3 1 0 0 1 1 1 0 Myelin basic protein Palm_thioest PF02089.15 KXZ45266.1 - 0.22 11.3 0.0 0.41 10.4 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Ank_2 PF12796.7 KXZ45268.1 - 0.0001 22.8 0.0 0.064 13.8 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ45268.1 - 0.00056 20.2 0.6 3.2 8.2 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ion_trans PF00520.31 KXZ45268.1 - 0.0062 15.8 2.8 0.01 15.1 2.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 KXZ45268.1 - 0.011 16.3 0.1 6.4 7.5 0.0 4.4 5 1 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45268.1 - 0.26 12.0 0.6 57 4.8 0.0 4.1 3 0 0 3 3 3 0 Ankyrin repeat Radical_SAM PF04055.21 KXZ45270.1 - 4.9e-16 59.5 0.0 1.2e-15 58.3 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KXZ45270.1 - 0.0001 22.4 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain STG PF15809.5 KXZ45270.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Simian taste bud-specific gene product family Fer4_12 PF13353.6 KXZ45270.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain OTU PF02338.19 KXZ45272.1 - 1.9e-24 86.6 0.0 3.7e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXZ45272.1 - 4.6e-09 36.1 0.0 0.00011 21.7 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain Hamartin PF04388.12 KXZ45272.1 - 8 5.0 7.1 9.8 4.7 7.1 1.1 1 0 0 1 1 1 0 Hamartin protein adh_short_C2 PF13561.6 KXZ45274.1 - 1.3e-60 204.9 4.2 1.5e-60 204.7 4.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ45274.1 - 1.6e-42 145.2 0.7 2e-42 144.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ45274.1 - 2.4e-13 50.4 0.9 3.6e-13 49.8 0.9 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXZ45274.1 - 0.00015 21.7 2.5 0.00025 21.0 2.4 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXZ45274.1 - 0.00036 20.1 0.2 0.0005 19.6 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FtsK_SpoIIIE PF01580.18 KXZ45274.1 - 0.0027 17.1 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family Polysacc_synt_2 PF02719.15 KXZ45274.1 - 0.028 13.6 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.16 KXZ45274.1 - 0.067 12.8 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rhodanese PF00581.20 KXZ45275.1 - 1.9e-08 34.7 0.0 3e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain Sulfotransfer_4 PF17784.1 KXZ45276.1 - 5.9e-56 189.7 0.1 2.8e-55 187.5 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Rhodanese PF00581.20 KXZ45277.1 - 4.5e-11 43.2 0.0 7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Pex14_N PF04695.13 KXZ45277.1 - 3.1 8.4 8.3 7.2 7.2 8.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pyridoxal_deC PF00282.19 KXZ45278.1 - 1.6e-109 366.0 0.0 2e-109 365.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Gelsolin PF00626.22 KXZ45279.1 - 4.5e-46 154.6 0.0 1.8e-13 50.2 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat Pkinase_Tyr PF07714.17 KXZ45280.1 - 1.3e-25 90.2 0.0 1.1e-11 44.5 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ45280.1 - 7.8e-21 74.6 0.0 6.4e-08 32.3 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain BatD PF13584.6 KXZ45280.1 - 0.07 11.9 0.4 0.11 11.3 0.4 1.1 1 0 0 1 1 1 0 Oxygen tolerance MscS_TM PF12794.7 KXZ45280.1 - 0.26 10.1 3.7 0.47 9.3 3.7 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SAP130_C PF16014.5 KXZ45281.1 - 8.1 5.4 16.7 16 4.5 16.7 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF3641 PF12345.8 KXZ45282.1 - 1.1e-49 168.0 0.0 2.1e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 KXZ45282.1 - 2.3e-06 28.1 0.0 4.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXZ45282.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Ank_2 PF12796.7 KXZ45283.1 - 1.5e-15 57.5 0.1 1.7e-09 38.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45283.1 - 5.2e-14 52.4 0.2 1.4e-06 28.8 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45283.1 - 1.6e-12 46.4 0.1 0.00041 20.6 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KXZ45283.1 - 2.1e-11 43.7 0.4 0.0079 16.6 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ45283.1 - 7.5e-09 35.7 1.6 0.00065 19.9 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PspA_IM30 PF04012.12 KXZ45284.1 - 7.4e-05 22.4 2.5 7.4e-05 22.4 2.5 1.6 2 0 0 2 2 1 1 PspA/IM30 family Csm1_N PF18504.1 KXZ45284.1 - 0.00012 22.3 6.2 0.00077 19.8 3.7 2.5 2 0 0 2 2 2 1 Csm1 N-terminal domain SlyX PF04102.12 KXZ45284.1 - 0.00039 21.0 6.7 0.0074 16.9 4.9 2.6 2 0 0 2 2 2 1 SlyX Cnn_1N PF07989.11 KXZ45284.1 - 0.00066 19.8 2.0 0.0073 16.4 0.7 2.3 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 ZapB PF06005.12 KXZ45284.1 - 0.00067 20.0 9.0 0.00069 20.0 6.2 2.4 2 1 0 2 2 1 1 Cell division protein ZapB TPR_MLP1_2 PF07926.12 KXZ45284.1 - 0.00068 19.7 6.4 0.00081 19.4 3.7 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein K-box PF01486.17 KXZ45284.1 - 0.00081 19.5 4.3 1.8 8.8 3.6 3.3 2 1 1 3 3 3 1 K-box region Lzipper-MIP1 PF14389.6 KXZ45284.1 - 0.0011 19.2 2.2 0.038 14.3 0.9 2.5 1 1 1 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 YabA PF06156.13 KXZ45284.1 - 0.002 18.7 2.3 0.0076 16.9 2.3 2.1 1 1 0 1 1 1 1 Initiation control protein YabA DUF4407 PF14362.6 KXZ45284.1 - 0.0031 16.9 1.6 0.0031 16.9 1.6 1.7 1 1 0 2 2 2 1 Domain of unknown function (DUF4407) DivIC PF04977.15 KXZ45284.1 - 0.0049 16.6 6.3 0.022 14.5 3.5 2.6 2 1 0 2 2 2 1 Septum formation initiator SOGA PF11365.8 KXZ45284.1 - 0.0061 17.7 3.1 0.057 14.5 0.8 2.7 2 1 1 3 3 2 1 Protein SOGA HALZ PF02183.18 KXZ45284.1 - 0.0069 16.6 8.2 0.11 12.7 1.0 3.1 2 1 1 3 3 3 1 Homeobox associated leucine zipper DUF4472 PF14739.6 KXZ45284.1 - 0.0074 17.0 4.5 0.057 14.2 3.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4472) TSC22 PF01166.18 KXZ45284.1 - 0.01 16.2 2.9 0.064 13.6 0.4 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family Spc24 PF08286.11 KXZ45284.1 - 0.018 15.2 1.1 0.21 11.8 0.8 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.7 KXZ45284.1 - 0.025 14.7 4.8 0.079 13.1 4.8 1.7 1 1 0 1 1 1 0 Tropomyosin like Spc7 PF08317.11 KXZ45284.1 - 0.027 13.3 3.9 0.041 12.8 3.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 KXZ45284.1 - 0.027 13.8 4.1 0.051 12.9 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAP1_N PF04849.13 KXZ45284.1 - 0.028 13.7 5.0 0.23 10.6 3.3 2.1 2 0 0 2 2 2 0 HAP1 N-terminal conserved region NPV_P10 PF05531.12 KXZ45284.1 - 0.03 14.8 0.2 0.32 11.5 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.8 KXZ45284.1 - 0.033 14.3 3.5 0.033 14.3 3.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding COG7 PF10191.9 KXZ45284.1 - 0.036 12.3 1.1 0.048 11.9 1.1 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) HMMR_C PF15908.5 KXZ45284.1 - 0.038 14.3 0.5 0.088 13.1 0.5 1.6 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal BLOC1_2 PF10046.9 KXZ45284.1 - 0.04 14.2 1.2 0.082 13.2 1.2 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.13 KXZ45284.1 - 0.04 14.0 2.1 7.6 6.7 1.5 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 KASH_CCD PF14662.6 KXZ45284.1 - 0.05 13.4 7.2 0.2 11.5 4.3 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Leu_zip PF15294.6 KXZ45284.1 - 0.051 13.1 1.7 0.082 12.4 1.7 1.3 1 0 0 1 1 1 0 Leucine zipper Mto2_bdg PF12808.7 KXZ45284.1 - 0.057 13.7 5.1 1.6 9.1 1.3 2.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GAS PF13851.6 KXZ45284.1 - 0.1 12.0 4.0 0.11 11.8 2.4 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tektin PF03148.14 KXZ45284.1 - 0.1 11.4 3.5 0.13 11.0 1.0 2.0 2 0 0 2 2 2 0 Tektin family PRKG1_interact PF15898.5 KXZ45284.1 - 0.13 13.1 3.6 0.4 11.6 1.4 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Wtap PF17098.5 KXZ45284.1 - 0.14 12.1 6.7 0.27 11.1 4.5 2.1 2 0 0 2 2 2 0 WTAP/Mum2p family TPD52 PF04201.15 KXZ45284.1 - 0.16 11.6 4.0 0.38 10.3 1.4 2.1 1 1 1 2 2 2 0 Tumour protein D52 family DUF5082 PF16888.5 KXZ45284.1 - 0.16 12.2 4.3 0.68 10.2 4.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 KXZ45284.1 - 0.18 11.9 4.4 0.35 11.0 0.4 2.6 2 1 1 3 3 2 0 bZIP transcription factor Herpes_UL6 PF01763.16 KXZ45284.1 - 0.19 10.2 0.9 0.24 9.9 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like YscO PF07321.12 KXZ45284.1 - 0.19 11.7 8.7 0.1 12.6 4.0 2.6 3 0 0 3 3 3 0 Type III secretion protein YscO DUF3573 PF12097.8 KXZ45284.1 - 0.23 10.3 0.9 0.31 9.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APG6_N PF17675.1 KXZ45284.1 - 0.23 12.0 6.5 0.17 12.4 4.4 1.8 2 0 0 2 2 1 0 Apg6 coiled-coil region Mod_r PF07200.13 KXZ45284.1 - 0.24 11.5 7.5 0.2 11.8 5.6 1.7 1 1 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein EzrA PF06160.12 KXZ45284.1 - 0.25 9.5 3.0 0.11 10.6 0.9 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CASP_C PF08172.12 KXZ45284.1 - 0.35 10.2 5.6 0.042 13.2 1.3 1.7 2 0 0 2 2 2 0 CASP C terminal V_ATPase_I PF01496.19 KXZ45284.1 - 0.36 8.7 1.2 0.46 8.3 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.6 KXZ45284.1 - 0.4 11.1 5.1 0.65 10.4 2.2 2.2 2 0 0 2 2 2 0 Snapin/Pallidin CENP-H PF05837.12 KXZ45284.1 - 0.41 11.1 5.3 1.4 9.4 5.3 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Fez1 PF06818.15 KXZ45284.1 - 0.44 11.0 8.1 2 8.8 5.0 2.4 1 1 1 2 2 2 0 Fez1 BRE1 PF08647.11 KXZ45284.1 - 0.52 10.4 5.9 2.3 8.4 1.1 2.9 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4763 PF15960.5 KXZ45284.1 - 0.54 9.5 6.7 0.32 10.3 2.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) TMF_DNA_bd PF12329.8 KXZ45284.1 - 0.55 10.3 6.1 0.89 9.6 3.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.6 KXZ45284.1 - 0.56 10.2 15.0 1.3 9.1 6.8 3.6 3 1 0 3 3 3 0 FlxA-like protein BST2 PF16716.5 KXZ45284.1 - 0.63 10.7 8.0 9.6 6.9 4.3 3.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4140 PF13600.6 KXZ45284.1 - 0.81 10.2 6.6 1.3 9.5 2.8 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4618 PF15397.6 KXZ45284.1 - 0.83 9.0 6.9 0.1 12.0 2.3 1.7 3 0 0 3 3 1 0 Domain of unknown function (DUF4618) GrpE PF01025.19 KXZ45284.1 - 0.89 9.2 4.8 0.37 10.4 2.4 1.5 2 0 0 2 2 1 0 GrpE ABC_tran_CTD PF16326.5 KXZ45284.1 - 1.1 9.5 6.1 2 8.7 3.4 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain TMF_TATA_bd PF12325.8 KXZ45284.1 - 1.5 9.1 7.7 1.3 9.3 4.0 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Rootletin PF15035.6 KXZ45284.1 - 1.7 8.6 8.5 9.9 6.1 8.2 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 KXZ45284.1 - 2 7.5 8.0 0.55 9.3 3.7 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uso1_p115_C PF04871.13 KXZ45284.1 - 2.6 8.4 7.1 11 6.4 3.4 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nnf1 PF03980.14 KXZ45284.1 - 2.6 8.4 10.0 0.16 12.4 3.7 2.2 2 1 0 2 2 2 0 Nnf1 DUF5320 PF17253.2 KXZ45284.1 - 5.5 8.1 8.5 52 5.0 0.0 3.4 3 2 0 3 3 2 0 Family of unknown function (DUF5320) NUDE_C PF04880.13 KXZ45284.1 - 9.1 6.7 12.1 0.12 12.8 1.7 2.2 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Clat_adaptor_s PF01217.20 KXZ45285.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SPOC PF07744.13 KXZ45286.1 - 7.6e-11 42.1 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KXZ45286.1 - 9.1e-05 22.2 0.0 0.0018 18.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRF_C1 PF13887.6 KXZ45287.1 - 0.17 11.0 0.8 0.92 8.7 0.8 2.3 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 GCIP PF13324.6 KXZ45287.1 - 0.2 11.3 4.1 0.41 10.2 4.1 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting YabA PF06156.13 KXZ45287.1 - 0.54 10.9 30.7 0.67 10.6 0.9 6.0 3 2 2 5 5 5 0 Initiation control protein YabA Adaptin_binding PF10199.9 KXZ45287.1 - 3.1 8.4 20.3 20 5.8 8.5 4.0 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 DnaJ PF00226.31 KXZ45288.1 - 2.4e-10 40.4 0.0 4.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Exostosin PF03016.15 KXZ45289.1 - 1.7e-27 96.5 1.1 1.9e-27 96.2 0.0 1.7 2 1 0 2 2 2 1 Exostosin family EGF_2 PF07974.13 KXZ45289.1 - 0.00011 22.5 13.0 0.00029 21.1 13.0 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 KXZ45289.1 - 0.023 14.8 5.0 0.051 13.6 5.0 1.6 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 KXZ45289.1 - 0.16 12.7 7.4 0.58 10.9 7.4 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF I-EGF_1 PF18372.1 KXZ45289.1 - 0.81 9.8 8.1 2.3 8.4 8.1 1.8 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 KXZ45289.1 - 1.2 9.5 13.9 0.88 9.9 10.1 2.5 2 0 0 2 2 2 0 EGF-like domain Exostosin PF03016.15 KXZ45290.1 - 1.5e-08 34.3 1.0 1.5e-08 34.3 1.0 2.6 2 1 0 2 2 2 1 Exostosin family EGF_2 PF07974.13 KXZ45290.1 - 9.6e-05 22.7 12.3 9.6e-05 22.7 12.3 2.5 2 0 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 KXZ45290.1 - 0.042 13.9 6.9 0.042 13.9 6.9 1.8 2 0 0 2 2 2 0 Tenascin EGF domain I-EGF_1 PF18372.1 KXZ45290.1 - 0.069 13.2 7.7 0.21 11.7 7.7 1.8 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Exostosin PF03016.15 KXZ45291.1 - 3.8e-14 52.6 0.0 5.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Pro_isomerase PF00160.21 KXZ45292.1 - 2.9e-22 79.6 0.0 4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PSI_PSAK PF01241.18 KXZ45293.1 - 1.4e-14 53.8 0.1 2.1e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Photosystem I psaG / psaK Ank_2 PF12796.7 KXZ45294.1 - 0.0013 19.2 1.0 6.9 7.3 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_2 PF12796.7 KXZ45295.1 - 6.3e-06 26.7 0.2 0.00034 21.2 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45295.1 - 0.00014 22.3 2.0 0.42 11.3 1.7 3.9 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45295.1 - 0.037 14.6 1.3 32 5.6 0.0 4.3 5 1 0 5 5 5 0 Ankyrin repeat Ank_4 PF13637.6 KXZ45296.1 - 3.3e-06 27.5 2.9 0.53 10.9 0.0 4.6 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45296.1 - 8.5e-06 26.3 0.1 0.0091 16.6 0.1 3.5 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45296.1 - 0.00013 22.1 1.1 7.2 7.5 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 KXZ45297.1 - 0.0012 19.4 0.1 0.55 10.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45297.1 - 0.0018 18.8 3.1 8.2 7.1 0.0 5.4 3 3 1 4 4 4 1 Ankyrin repeats (many copies) DUF3390 PF11870.8 KXZ45297.1 - 0.057 13.8 1.7 1.6 9.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) DUF434 PF04256.12 KXZ45297.1 - 0.15 11.8 0.0 27 4.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF434) IQ PF00612.27 KXZ45298.1 - 4.7e-07 29.0 3.3 1.2e-06 27.8 3.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Sec23_trunk PF04811.15 KXZ45298.1 - 0.065 12.8 4.5 0.022 14.3 1.6 1.7 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain TPR_12 PF13424.6 KXZ45300.1 - 1.4e-21 76.6 10.9 5.7e-14 52.2 4.0 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ45300.1 - 4.4e-19 67.7 26.4 5.3e-10 38.8 0.2 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ45300.1 - 5.9e-08 32.2 14.8 0.00012 21.8 0.2 5.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ45300.1 - 3.4e-07 29.8 11.7 0.0022 17.7 0.3 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ45300.1 - 2.1e-06 27.4 2.6 0.00043 20.2 0.8 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ45300.1 - 1.5e-05 25.5 6.2 1.5e-05 25.5 6.2 7.2 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ45300.1 - 4.9e-05 23.7 0.9 4.9e-05 23.7 0.9 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ45300.1 - 0.00087 19.5 6.2 0.54 10.8 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45300.1 - 0.004 17.2 15.2 0.024 14.8 0.0 5.1 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ45300.1 - 0.0047 17.4 1.4 0.19 12.5 0.2 9.8 8 3 4 12 12 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ45300.1 - 0.008 16.8 0.1 0.008 16.8 0.1 5.7 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ45300.1 - 0.015 16.1 0.1 0.015 16.1 0.1 9.0 7 3 2 9 9 9 0 Tetratricopeptide repeat MIT PF04212.18 KXZ45300.1 - 0.34 11.0 4.8 0.9 9.7 0.0 3.3 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Sporozoite_P67 PF05642.11 KXZ45300.1 - 4 5.4 5.3 6.2 4.8 5.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRM_1 PF00076.22 KXZ45301.1 - 1.3e-07 31.4 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Orai-1 PF07856.12 KXZ45303.1 - 1.4e-27 96.5 2.5 5.8e-22 78.2 1.2 2.1 2 0 0 2 2 2 2 Mediator of CRAC channel activity Phage_holin_3_6 PF07332.11 KXZ45303.1 - 0.036 14.1 1.0 0.036 14.1 1.0 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2975 PF11188.8 KXZ45303.1 - 0.096 12.6 1.8 0.13 12.1 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) GATA PF00320.27 KXZ45304.1 - 9.7e-15 53.9 3.3 2.1e-14 52.8 3.3 1.6 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KXZ45304.1 - 0.32 11.1 3.7 0.33 11.1 2.0 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Nudix_N_2 PF14803.6 KXZ45304.1 - 1.6 8.7 5.7 4.6 7.2 5.7 1.8 1 0 0 1 1 1 0 Nudix N-terminal Ank_4 PF13637.6 KXZ45305.1 - 1.3e-05 25.6 5.1 5 7.8 0.0 5.6 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45305.1 - 0.00011 22.7 0.4 0.0099 16.4 0.1 3.2 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) PNTB PF02233.16 KXZ45305.1 - 0.0036 16.3 0.2 0.005 15.8 0.2 1.1 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit Ank_3 PF13606.6 KXZ45305.1 - 0.021 15.3 1.2 1.2e+02 3.8 0.0 5.2 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 KXZ45307.1 - 6.1e-09 36.4 0.2 0.6 10.7 0.0 5.9 4 1 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45307.1 - 2.7e-08 34.2 7.2 4.3 8.0 0.0 9.7 7 3 4 11 11 11 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45307.1 - 0.00072 19.8 3.6 2.4e+02 2.8 0.0 8.4 11 0 0 11 11 11 0 Ankyrin repeat Ank_5 PF13857.6 KXZ45307.1 - 0.0029 17.9 1.4 13 6.2 0.0 5.6 4 1 2 6 6 6 1 Ankyrin repeats (many copies) PPR_2 PF13041.6 KXZ45307.1 - 0.023 14.9 0.0 4.3 7.6 0.0 3.2 4 0 0 4 4 4 0 PPR repeat family Ad_Cy_reg PF16701.5 KXZ45307.1 - 0.092 12.5 0.0 23 4.7 0.0 3.5 3 0 0 3 3 3 0 Adenylate cyclase regulatory domain ATX_III PF08098.11 KXZ45307.1 - 2 8.5 19.2 9.5 6.4 0.5 5.3 5 0 0 5 5 5 0 Anemonia sulcata toxin III family Ank_2 PF12796.7 KXZ45308.1 - 4.2e-05 24.1 0.5 0.35 11.5 0.4 3.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45308.1 - 0.024 15.2 1.4 1.7 9.3 0.5 3.6 2 2 1 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ45308.1 - 0.23 11.8 2.3 15 6.0 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45309.1 - 1.4e-05 25.6 0.5 0.41 11.3 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45309.1 - 0.00018 22.0 3.3 4.1 8.1 0.1 5.3 4 2 0 4 4 4 3 Ankyrin repeats (many copies) Ricin_B_lectin PF00652.22 KXZ45310.1 - 7.6e-46 155.5 19.2 5.5e-19 68.7 3.1 3.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXZ45310.1 - 4.8e-33 113.7 15.7 3.1e-12 47.0 2.3 4.5 3 1 0 4 4 4 3 Ricin-type beta-trefoil lectin domain-like VOMI PF03762.17 KXZ45310.1 - 1.8e-29 103.0 3.9 1.8e-29 103.0 3.9 3.0 3 1 1 4 4 4 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ45310.1 - 1.8e-09 37.4 8.6 1e-05 25.2 0.9 3.1 1 1 2 3 3 3 3 Cytolethal distending toxin A/C domain EF-hand_1 PF00036.32 KXZ45310.1 - 0.00026 20.3 0.0 0.00057 19.3 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ45310.1 - 0.006 17.0 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ45310.1 - 0.0072 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXZ45310.1 - 0.025 14.1 0.1 0.058 12.9 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KXZ45310.1 - 0.063 13.1 0.2 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain pair DUF2722 PF10846.8 KXZ45312.1 - 0.093 11.7 8.5 0.13 11.1 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EIF4E-T PF10477.9 KXZ45312.1 - 0.36 9.6 10.8 0.52 9.1 10.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E NMDAR2_C PF10565.9 KXZ45312.1 - 0.38 9.6 4.8 0.55 9.0 4.8 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus TFIIA PF03153.13 KXZ45312.1 - 3.6 7.5 23.8 7.9 6.4 24.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF393 PF04134.12 KXZ45314.1 - 0.11 13.8 4.8 0.16 13.3 3.9 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF393 Pneumo_M2 PF07380.11 KXZ45316.1 - 0.032 14.5 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Pneumovirus M2 protein Ank_2 PF12796.7 KXZ45317.1 - 2.8e-05 24.6 1.5 0.089 13.4 0.1 3.8 2 1 2 4 4 4 1 Ankyrin repeats (3 copies) DUF2052 PF09747.9 KXZ45317.1 - 0.00098 19.3 4.6 0.0014 18.8 4.6 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Ank_4 PF13637.6 KXZ45317.1 - 0.0019 18.8 1.7 16 6.2 0.0 4.7 3 2 1 4 4 4 0 Ankyrin repeats (many copies) FAM176 PF14851.6 KXZ45317.1 - 0.0058 16.3 1.9 0.01 15.5 1.9 1.3 1 0 0 1 1 1 1 FAM176 family DUF3449 PF11931.8 KXZ45317.1 - 0.013 15.3 4.7 0.02 14.7 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) GEN1_C PF18380.1 KXZ45317.1 - 0.019 15.8 4.7 0.041 14.8 2.1 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Ank_3 PF13606.6 KXZ45317.1 - 0.028 14.9 0.9 1.1e+02 4.0 0.0 5.4 5 1 1 6 6 4 0 Ankyrin repeat TRAP_alpha PF03896.16 KXZ45317.1 - 0.03 13.5 1.9 0.04 13.1 1.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 KXZ45317.1 - 0.14 11.6 8.7 0.24 10.8 8.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BSP_II PF05432.11 KXZ45317.1 - 0.15 11.8 13.1 0.22 11.2 13.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) WRNPLPNID PF15017.6 KXZ45317.1 - 0.18 12.7 13.6 0.35 11.8 13.6 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box RXT2_N PF08595.11 KXZ45317.1 - 0.23 11.5 5.3 0.35 10.9 5.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Saw1 PF11561.8 KXZ45317.1 - 0.25 10.8 0.7 0.36 10.3 0.7 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 SDA1 PF05285.12 KXZ45317.1 - 0.26 10.7 10.0 0.36 10.2 10.0 1.1 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 KXZ45317.1 - 0.3 11.2 1.4 0.46 10.6 1.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 KXZ45317.1 - 0.46 8.5 18.5 0.67 8.0 18.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KXZ45317.1 - 0.69 8.1 13.4 0.95 7.6 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 KXZ45317.1 - 0.84 7.3 3.2 1.1 6.9 3.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sigma70_ner PF04546.13 KXZ45317.1 - 1.5 8.7 11.9 2.5 7.9 11.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop53 PF07767.11 KXZ45317.1 - 1.7 7.9 12.4 2.3 7.5 12.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KXZ45317.1 - 1.9 6.7 10.1 2.8 6.1 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 KXZ45317.1 - 2 8.1 6.5 3.3 7.4 6.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RNA_pol_3_Rpc31 PF11705.8 KXZ45317.1 - 2.4 8.4 20.4 3.4 7.8 20.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 KXZ45317.1 - 2.4 7.9 8.8 3.8 7.3 8.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 KXZ45317.1 - 2.8 7.3 11.1 4.2 6.7 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Radial_spoke PF04712.12 KXZ45317.1 - 3.4 6.5 15.2 4.8 6.0 15.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein NOA36 PF06524.12 KXZ45317.1 - 5.1 6.3 15.0 9.8 5.4 15.0 1.4 1 0 0 1 1 1 0 NOA36 protein HSP90 PF00183.18 KXZ45317.1 - 5.1 5.9 11.2 7 5.4 11.2 1.1 1 0 0 1 1 1 0 Hsp90 protein Paf1 PF03985.13 KXZ45317.1 - 5.3 5.9 15.7 7.3 5.5 15.7 1.1 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 KXZ45317.1 - 9.1 6.2 7.8 14 5.6 7.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ank_2 PF12796.7 KXZ45318.1 - 1.4e-09 38.4 0.6 0.00014 22.3 0.1 4.1 4 2 0 4 4 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45318.1 - 6.6e-07 29.8 8.0 0.06 14.0 1.1 5.3 5 2 0 5 5 5 2 Ankyrin repeats (many copies) DUF2052 PF09747.9 KXZ45318.1 - 0.0051 17.0 4.0 0.007 16.5 4.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) AbiEi_3_N PF17194.4 KXZ45318.1 - 0.017 15.2 0.0 9.7 6.3 0.0 3.6 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain FAM176 PF14851.6 KXZ45318.1 - 0.099 12.3 3.6 0.18 11.5 3.6 1.4 1 0 0 1 1 1 0 FAM176 family Ank_5 PF13857.6 KXZ45318.1 - 0.12 12.7 5.3 73 3.9 0.0 5.3 5 1 1 6 6 6 0 Ankyrin repeats (many copies) BSP_II PF05432.11 KXZ45318.1 - 0.15 11.8 14.5 0.21 11.3 14.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 KXZ45318.1 - 0.17 11.3 5.9 0.23 10.9 5.9 1.1 1 0 0 1 1 1 0 SDA1 NeuB PF03102.14 KXZ45318.1 - 0.17 11.3 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 NeuB family Radial_spoke PF04712.12 KXZ45318.1 - 0.22 10.4 11.8 0.31 9.9 11.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Ank_3 PF13606.6 KXZ45318.1 - 0.44 11.2 7.8 19 6.2 0.1 6.1 8 0 0 8 8 6 0 Ankyrin repeat DUF4746 PF15928.5 KXZ45318.1 - 0.45 9.9 7.3 0.64 9.4 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 KXZ45318.1 - 2.7 6.1 10.4 3.7 5.6 10.4 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 KXZ45318.1 - 8.9 5.2 13.4 12 4.7 13.4 1.1 1 0 0 1 1 1 0 Paf1 Myc_N PF01056.18 KXZ45318.1 - 9.3 6.0 7.3 14 5.4 7.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ank_2 PF12796.7 KXZ45319.1 - 2e-10 41.1 0.1 0.00082 19.9 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45319.1 - 0.00015 21.9 0.8 17 6.4 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXZ45319.1 - 0.00064 20.2 6.8 1.2 9.8 2.0 5.5 3 3 2 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ45319.1 - 0.0096 16.2 1.8 3.3 8.1 0.2 3.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45320.1 - 2e-10 41.1 0.2 0.00062 20.3 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45320.1 - 1e-07 32.3 3.4 0.67 10.6 0.0 6.6 4 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45320.1 - 8.8e-05 22.6 4.1 22 6.1 0.0 6.9 8 0 0 8 8 8 1 Ankyrin repeat Cut8 PF08559.10 KXZ45320.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.1 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein RCC1 PF00415.18 KXZ45322.1 - 2.7e-44 149.6 14.0 2.3e-10 41.0 0.0 7.0 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ45322.1 - 2.4e-17 62.2 29.9 9.6e-09 34.8 0.4 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 KXZ45322.1 - 0.077 13.2 1.4 5.9 7.2 1.4 2.7 1 1 0 1 1 1 0 Putative heavy-metal chelation MIOX PF05153.15 KXZ45324.1 - 4.1e-56 190.3 0.0 5.6e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase RNase_P_Rpp14 PF01900.19 KXZ45325.1 - 8.1e-13 48.5 0.1 5.8e-12 45.8 0.1 2.0 1 1 1 2 2 2 1 Rpp14/Pop5 family PPR PF01535.20 KXZ45326.1 - 4.7e-07 29.6 0.0 0.074 13.3 0.0 3.3 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 KXZ45326.1 - 5.2e-07 29.8 0.0 0.0065 16.6 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 KXZ45326.1 - 0.0079 15.6 1.5 0.021 14.2 1.5 1.9 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KXZ45326.1 - 0.019 15.7 14.5 0.48 11.4 0.4 4.0 1 1 3 4 4 4 0 Tetratricopeptide repeat Leu_Phe_trans PF03588.14 KXZ45326.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 KXZ45326.1 - 0.092 12.9 2.5 0.23 11.6 2.2 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_16 PF13432.6 KXZ45326.1 - 1.1 10.0 15.6 1.4 9.7 0.3 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ45326.1 - 5.7 7.8 9.1 5.3 7.9 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Alpha-2-MRAP_N PF06400.11 KXZ45328.1 - 0.041 13.9 4.1 0.048 13.6 4.1 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain ShK PF01549.24 KXZ45330.1 - 3.4e-07 30.7 6.1 5.8e-07 29.9 6.1 1.3 1 0 0 1 1 1 1 ShK domain-like Melibiase_C PF17801.1 KXZ45330.1 - 0.00084 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain DUF641 PF04859.12 KXZ45330.1 - 0.016 15.6 0.2 0.025 14.9 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) FAM76 PF16046.5 KXZ45330.1 - 0.051 12.9 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 FAM76 protein Geminin PF07412.12 KXZ45330.1 - 0.1 12.3 0.9 0.15 11.7 0.9 1.2 1 0 0 1 1 1 0 Geminin Macoilin PF09726.9 KXZ45330.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Macoilin family CASP_C PF08172.12 KXZ45330.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 CASP C terminal TolA_bind_tri PF16331.5 KXZ45330.1 - 0.23 11.6 1.5 0.35 11.0 1.5 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation FlaC_arch PF05377.11 KXZ45330.1 - 0.24 11.8 1.2 0.36 11.3 1.2 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) T2SSM PF04612.12 KXZ45330.1 - 2.6 8.1 7.6 1.4 9.0 4.8 1.9 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M RRM_1 PF00076.22 KXZ45332.1 - 8e-29 99.3 0.0 2.5e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ45332.1 - 0.00022 21.3 0.0 0.0024 17.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KXZ45332.1 - 0.039 14.0 0.0 4 7.5 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXZ45332.1 - 0.26 11.2 0.0 0.7 9.8 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif Glypican PF01153.19 KXZ45332.1 - 1.1 8.1 6.1 1.5 7.6 6.1 1.2 1 0 0 1 1 1 0 Glypican EXS PF03124.14 KXZ45333.1 - 1.9e-69 234.5 6.6 2.6e-69 234.1 6.6 1.2 1 0 0 1 1 1 1 EXS family Rtt106 PF08512.12 KXZ45334.1 - 5.6e-25 87.6 0.0 2.7e-23 82.2 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HMG_box PF00505.19 KXZ45334.1 - 5.7e-23 81.1 1.7 9.6e-23 80.4 1.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box SSrecog PF03531.14 KXZ45334.1 - 3.1e-17 62.2 0.0 8.6e-17 60.8 0.0 1.8 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KXZ45334.1 - 1.6e-14 54.1 0.0 5.1e-13 49.3 0.0 2.7 2 0 0 2 2 2 1 POB3-like N-terminal PH domain HMG_box_2 PF09011.10 KXZ45334.1 - 2.6e-14 53.6 2.3 5.6e-14 52.5 2.3 1.6 1 0 0 1 1 1 1 HMG-box domain YL1 PF05764.13 KXZ45334.1 - 0.36 10.9 16.2 0.58 10.2 16.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 KXZ45334.1 - 6.9 4.8 12.2 9.9 4.2 12.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXZ45334.1 - 8.8 4.5 8.1 12 4.1 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KXZ45334.1 - 9.9 4.1 10.3 14 3.6 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CLTH PF10607.9 KXZ45335.1 - 1.7e-34 118.8 0.0 2e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXZ45335.1 - 2.7e-11 43.0 0.3 9.3e-11 41.3 0.1 2.0 2 0 0 2 2 2 1 LisH Sld5 PF05916.11 KXZ45336.1 - 3e-19 69.5 0.2 5.1e-19 68.7 0.0 1.4 2 0 0 2 2 2 1 GINS complex protein DUF3907 PF13047.6 KXZ45336.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) Biopterin_H PF00351.21 KXZ45337.1 - 2e-86 290.1 0.0 2.3e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Peptidase_C50 PF03568.17 KXZ45338.1 - 2.7e-83 280.3 0.0 1.7e-67 228.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 KXZ45338.1 - 3e-06 26.9 3.9 0.00023 20.7 0.4 3.6 2 1 0 2 2 2 1 CHAT domain Strumpellin PF10266.9 KXZ45338.1 - 0.28 8.8 0.0 0.42 8.3 0.0 1.1 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin TPR_2 PF07719.17 KXZ45338.1 - 0.45 10.8 3.5 1.7 9.0 1.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Glycos_trans_3N PF02885.17 KXZ45338.1 - 1.5 8.7 6.1 4.2 7.3 0.3 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain TPR_14 PF13428.6 KXZ45338.1 - 2.7 9.0 9.1 2 9.5 1.4 4.4 2 1 1 3 3 3 0 Tetratricopeptide repeat LRR_9 PF14580.6 KXZ45339.1 - 1.5e-20 73.4 0.5 2.1e-15 56.6 0.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KXZ45339.1 - 3e-17 62.4 14.6 5.6e-06 26.6 1.1 3.9 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ45339.1 - 9.8e-11 41.3 10.0 2.4e-05 24.0 1.8 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KXZ45339.1 - 0.15 12.7 14.4 9.9 7.2 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KXZ45339.1 - 0.45 10.7 0.1 0.45 10.7 0.1 4.8 6 0 0 6 6 6 0 Leucine Rich repeat Trypsin_2 PF13365.6 KXZ45340.1 - 1.4e-32 113.7 0.3 3e-32 112.6 0.3 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXZ45340.1 - 1.2e-13 51.3 0.0 2.2e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KXZ45340.1 - 1e-11 45.0 0.0 2.4e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KXZ45340.1 - 6.9e-05 22.6 1.9 0.13 12.1 0.2 2.7 2 0 0 2 2 2 2 PDZ domain Peptidase_S29 PF02907.15 KXZ45340.1 - 0.003 17.3 0.1 0.0092 15.7 0.1 1.8 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 KXZ45340.1 - 0.03 13.0 0.8 0.59 8.7 1.0 2.1 2 0 0 2 2 2 0 Peptidase S46 PDZ PF00595.24 KXZ45340.1 - 0.041 14.2 1.6 0.9 9.9 1.0 2.8 2 1 0 2 2 2 0 PDZ domain Hydrolase_4 PF12146.8 KXZ45342.1 - 7.4e-57 192.4 0.4 1e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ45342.1 - 2.1e-11 44.9 7.5 3.1e-11 44.3 7.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ45342.1 - 5.3e-10 39.4 0.0 4.8e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXZ45342.1 - 0.0032 17.1 0.0 0.006 16.3 0.0 1.5 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KXZ45342.1 - 0.004 16.9 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KXZ45342.1 - 0.0053 16.6 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KXZ45342.1 - 0.0082 16.3 0.4 0.099 12.7 0.1 2.2 1 1 1 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 KXZ45342.1 - 0.024 14.5 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.16 KXZ45342.1 - 0.065 13.0 0.0 0.33 10.7 0.0 2.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase RMMBL PF07521.12 KXZ45342.1 - 0.16 11.9 0.0 17 5.4 0.0 2.7 3 0 0 3 3 3 0 Zn-dependent metallo-hydrolase RNA specificity domain DEAD PF00270.29 KXZ45343.1 - 3.1e-47 160.6 0.0 6.3e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ45343.1 - 3.5e-31 107.8 0.0 1.3e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ45343.1 - 1.7e-05 24.9 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXZ45343.1 - 0.0048 16.6 0.0 0.26 11.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain UTP25 PF06862.12 KXZ45343.1 - 0.1 11.4 0.0 1.5 7.5 0.0 2.5 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Complex1_LYR PF05347.15 KXZ45344.1 - 6.9e-13 48.4 2.9 1.2e-11 44.5 0.5 2.3 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXZ45344.1 - 0.051 14.3 0.1 0.17 12.7 0.0 1.9 2 0 0 2 2 2 0 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KXZ45344.1 - 0.1 13.2 0.8 1.8 9.2 0.1 2.6 2 1 0 3 3 3 0 Complex1_LYR-like DUF2076 PF09849.9 KXZ45345.1 - 0.029 14.4 2.4 0.036 14.1 2.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ATG_C PF09333.11 KXZ45345.1 - 0.11 12.9 0.9 2.6 8.5 0.2 2.1 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain TB2_DP1_HVA22 PF03134.19 KXZ45346.1 - 4.5e-11 42.5 2.7 7.3e-11 41.8 2.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mating_N PF12731.7 KXZ45346.1 - 0.083 13.0 1.7 12 6.1 0.0 3.5 2 0 0 2 2 2 0 Mating-type protein beta 1 TSC22 PF01166.18 KXZ45346.1 - 0.22 11.9 20.1 0.84 10.0 0.1 5.7 4 1 1 5 5 5 0 TSC-22/dip/bun family BLOC1_2 PF10046.9 KXZ45346.1 - 2.9 8.3 67.8 0.11 12.8 4.6 8.3 5 3 2 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4988 PF16378.5 KXZ45346.1 - 7.9 6.1 12.6 1.5 8.5 0.4 3.9 4 0 0 4 4 4 0 Domain of unknown function CIA30 PF08547.12 KXZ45347.1 - 5.9e-38 130.4 0.0 7.8e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) V-ATPase_H_N PF03224.14 KXZ45348.1 - 1.3e-63 215.2 0.4 3.5e-63 213.8 0.0 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KXZ45348.1 - 1.2e-39 135.0 0.3 9.4e-39 132.2 0.1 2.4 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.6 KXZ45348.1 - 0.013 15.8 1.8 1 9.8 0.0 3.8 3 1 1 4 4 4 0 HEAT repeats Arm PF00514.23 KXZ45348.1 - 0.028 14.5 6.9 1.8 8.7 0.0 4.8 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat MatE PF01554.18 KXZ45349.1 - 4.6e-56 188.9 25.9 5.8e-29 100.8 8.0 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ45349.1 - 1.3e-06 28.5 6.8 1.3e-06 28.5 6.8 3.6 2 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain Exostosin PF03016.15 KXZ45350.1 - 4.5e-26 91.8 1.0 8.7e-23 81.0 0.4 2.2 2 0 0 2 2 2 2 Exostosin family EGF_2 PF07974.13 KXZ45350.1 - 0.0053 17.1 15.4 0.0053 17.1 15.4 2.5 2 0 0 2 2 2 2 EGF-like domain I-EGF_1 PF18372.1 KXZ45350.1 - 0.58 10.3 9.6 1.3 9.2 9.6 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 PCI PF01399.27 KXZ45351.1 - 0.00062 20.2 0.0 0.0035 17.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain CRAL_TRIO PF00650.20 KXZ45353.1 - 1.4e-25 89.9 0.0 1.6e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain KH_1 PF00013.29 KXZ45354.1 - 3.9e-48 161.1 10.7 4e-16 58.6 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXZ45354.1 - 4.3e-12 45.7 1.9 0.0026 17.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXZ45354.1 - 4.9e-11 42.3 4.5 0.0055 16.5 0.1 3.4 3 0 0 3 3 3 3 KH domain WW PF00397.26 KXZ45354.1 - 2.6e-09 37.0 0.8 4.9e-09 36.1 0.8 1.4 1 0 0 1 1 1 1 WW domain MOEP19 PF16005.5 KXZ45354.1 - 1.3e-05 25.1 0.0 0.35 10.9 0.0 3.9 4 0 0 4 4 4 2 KH-like RNA-binding domain Glyco_hyd_101C PF17451.2 KXZ45354.1 - 0.042 14.1 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain KH_5 PF13184.6 KXZ45354.1 - 0.2 11.8 5.0 32 4.7 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain WD40 PF00400.32 KXZ45355.1 - 2.7e-07 31.2 3.8 0.033 15.1 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ45355.1 - 0.00038 20.7 0.0 0.39 11.0 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M11 PF05548.11 KXZ45357.1 - 7.4e-60 202.7 0.1 3.2e-59 200.6 0.1 1.9 1 1 0 1 1 1 1 Gametolysin peptidase M11 DUF5114 PF17141.4 KXZ45357.1 - 0.33 11.5 2.8 1 10.0 2.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5114) DUF563 PF04577.14 KXZ45358.1 - 2.1e-05 24.8 0.0 4.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DUF1921 PF09081.10 KXZ45358.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) Nucleotid_trans PF03407.16 KXZ45359.1 - 1.7e-09 38.0 0.1 2.2e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-C2HCIx2C PF10782.9 KXZ45359.1 - 0.089 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger Glyco_transf_8 PF01501.20 KXZ45359.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 Laminin_EGF PF00053.24 KXZ45362.1 - 0.0015 18.6 0.1 0.0026 17.8 0.1 1.3 1 0 0 1 1 1 1 Laminin EGF domain TRP PF06011.12 KXZ45364.1 - 0.02 13.6 2.6 0.038 12.7 2.6 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel MSC PF09402.10 KXZ45364.1 - 0.31 10.5 0.9 0.6 9.5 0.9 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Laminin_EGF PF00053.24 KXZ45364.1 - 5 7.3 9.7 0.7 10.1 5.0 2.0 2 0 0 2 2 2 0 Laminin EGF domain bZIP_1 PF00170.21 KXZ45365.1 - 0.0033 17.5 7.0 0.0079 16.3 6.6 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ45365.1 - 0.013 15.5 6.6 0.013 15.5 6.6 2.6 3 1 1 4 4 4 0 Basic region leucine zipper VGCC_beta4Aa_N PF12052.8 KXZ45365.1 - 8.3 6.6 7.2 35 4.6 2.4 2.9 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal TFIIA PF03153.13 KXZ45365.1 - 9.2 6.1 29.5 2 8.3 22.7 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3431 PF11913.8 KXZ45366.1 - 5.3e-12 46.0 1.3 4.9e-06 26.5 0.3 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3431) DUF2014 PF09427.10 KXZ45366.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) zf_C2H2_10 PF18414.1 KXZ45367.1 - 0.0012 18.3 3.0 0.0019 17.7 3.0 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger zf-Di19 PF05605.12 KXZ45367.1 - 0.003 17.8 1.4 0.0048 17.2 1.4 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXZ45367.1 - 0.013 16.3 0.3 0.022 15.6 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3431 PF11913.8 KXZ45368.1 - 1.9e-07 31.1 0.1 9e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) DUF2014 PF09427.10 KXZ45368.1 - 0.17 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Glyco_transf_90 PF05686.12 KXZ45369.1 - 1.6e-16 60.2 0.0 2.5e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Carb_anhydrase PF00194.21 KXZ45370.1 - 9.4e-43 146.6 0.0 1.4e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MFS_1 PF07690.16 KXZ45371.1 - 1.7e-19 70.0 51.3 2e-11 43.5 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ45371.1 - 0.00049 19.1 28.0 0.0069 15.3 10.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Hexapep PF00132.24 KXZ45372.1 - 6e-15 54.3 23.5 4e-06 26.3 1.5 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ45372.1 - 1.5e-06 27.8 14.7 5.8e-05 22.8 2.8 4.0 2 2 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXZ45372.1 - 0.075 11.2 3.3 0.43 8.7 2.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) MA3 PF02847.17 KXZ45373.1 - 7.6e-52 174.1 0.0 3.9e-17 62.3 0.0 4.1 4 0 0 4 4 4 4 MA3 domain DUF2458 PF10454.9 KXZ45373.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Ank_2 PF12796.7 KXZ45374.1 - 1.8e-09 38.1 0.1 0.038 14.6 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45374.1 - 6.1e-07 29.9 3.9 0.52 11.0 0.0 5.7 4 2 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45374.1 - 8.6e-06 25.7 1.0 25 5.9 0.0 7.1 8 0 0 8 8 8 1 Ankyrin repeat Arginosuc_synth PF00764.19 KXZ45375.1 - 1.2e-158 528.5 0.0 1.3e-158 528.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 KXZ45375.1 - 0.002 17.9 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 KXZ45375.1 - 0.0036 16.8 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC TPT PF03151.16 KXZ45377.1 - 5e-11 42.5 18.1 6.4e-11 42.1 18.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ45377.1 - 0.0026 17.9 12.6 0.0026 17.9 12.6 2.2 2 0 0 2 2 2 1 EamA-like transporter family Phage_holin_2_3 PF16080.5 KXZ45377.1 - 1.4 8.7 4.5 1.3 8.8 0.2 3.1 2 1 1 3 3 3 0 Bacteriophage holin family HP1 Kinesin PF00225.23 KXZ45381.1 - 2.2e-106 355.6 0.0 3e-106 355.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ45381.1 - 3.7e-24 85.4 0.0 6.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 KXZ45381.1 - 0.0021 18.3 2.6 0.007 16.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF3496 PF12001.8 KXZ45381.1 - 0.049 14.0 0.1 0.049 14.0 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3496) Tup_N PF08581.10 KXZ45381.1 - 0.18 12.1 7.1 4.5 7.7 0.1 3.0 3 0 0 3 3 3 0 Tup N-terminal AAA_7 PF12775.7 KXZ45381.1 - 0.2 11.2 0.0 0.45 10.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SidE PF12252.8 KXZ45381.1 - 3.7 5.0 7.8 5 4.5 7.8 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Methyltransf_22 PF13383.6 KXZ45382.1 - 3.6e-17 62.8 0.0 6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXZ45382.1 - 1.5e-07 31.6 0.0 2.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Ank_2 PF12796.7 KXZ45383.1 - 9.7e-19 67.7 0.5 1.5e-05 25.5 0.1 4.6 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45383.1 - 6.2e-11 42.6 5.3 0.35 11.5 0.3 6.9 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45383.1 - 1.1e-09 37.7 0.5 2.6 8.9 0.0 8.7 10 0 0 10 10 10 1 Ankyrin repeat Ank_2 PF12796.7 KXZ45384.1 - 2e-14 54.0 0.2 5.2e-05 23.7 0.0 4.5 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45384.1 - 1.1e-11 45.0 0.6 0.0027 18.2 0.0 6.2 4 1 3 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45384.1 - 1e-09 37.8 0.0 16 6.5 0.0 8.1 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ45384.1 - 0.0002 21.6 1.9 2.2 8.7 0.0 6.1 5 2 3 8 8 8 1 Ankyrin repeats (many copies) AbiEi_3_N PF17194.4 KXZ45384.1 - 0.063 13.3 0.1 22 5.2 0.0 3.3 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain HTH_39 PF14090.6 KXZ45384.1 - 0.16 11.7 0.0 0.67 9.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Pkinase PF00069.25 KXZ45385.1 - 0.0036 16.7 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Macoilin PF09726.9 KXZ45386.1 - 0.036 12.6 8.5 0.043 12.4 8.5 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KXZ45386.1 - 0.088 11.6 10.7 0.13 11.1 10.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 KXZ45386.1 - 4 7.3 16.9 5.9 6.7 16.9 1.2 1 0 0 1 1 1 0 SPX domain Nucleo_P87 PF07267.11 KXZ45386.1 - 9.9 4.9 5.6 14 4.4 5.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pkinase PF00069.25 KXZ45387.1 - 0.00052 19.5 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PX PF00787.24 KXZ45388.1 - 1.4e-14 54.0 0.1 2.4e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 PX domain FAST_1 PF06743.15 KXZ45389.1 - 0.085 12.8 0.0 28 4.8 0.0 2.8 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 DUF563 PF04577.14 KXZ45390.1 - 2.7e-07 31.0 0.0 4.7e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Ank_2 PF12796.7 KXZ45391.1 - 5.4e-26 91.0 0.1 2.8e-09 37.4 0.2 4.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45391.1 - 4.2e-22 75.9 8.2 0.00011 22.4 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KXZ45391.1 - 3.4e-20 71.8 7.6 4.5e-09 36.4 0.0 5.1 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ45391.1 - 1.4e-19 69.6 11.7 4.6e-05 23.7 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KXZ45391.1 - 1.7e-19 69.9 2.2 8.5e-08 32.6 0.0 5.5 4 1 2 6 6 6 5 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 KXZ45391.1 - 3.3e-06 26.8 3.1 7.5e-06 25.7 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ45391.1 - 0.0086 15.9 6.5 0.022 14.6 6.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ45391.1 - 0.027 14.8 5.3 0.027 14.8 5.3 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 KXZ45391.1 - 0.11 12.4 4.5 0.29 11.1 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ45391.1 - 1.9 8.5 10.8 0.21 11.6 5.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXZ45391.1 - 2.9 8.1 7.2 7.7 6.8 7.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DSPc PF00782.20 KXZ45392.1 - 7.4e-26 90.5 0.0 1e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXZ45392.1 - 0.0001 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2749 PF10907.8 KXZ45392.1 - 0.0019 18.3 1.8 1.1 9.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2749) TPR_2 PF07719.17 KXZ45393.1 - 8.3e-21 72.4 7.9 0.005 16.8 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ45393.1 - 3.4e-16 59.3 2.4 2.1e-08 34.4 0.4 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ45393.1 - 4.9e-16 58.0 13.5 0.0054 17.5 0.2 6.5 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ45393.1 - 3.5e-13 49.9 7.8 0.0014 19.2 0.1 5.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ45393.1 - 2.6e-12 46.0 4.2 0.082 12.8 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ45393.1 - 1.6e-10 40.6 2.7 0.00056 20.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45393.1 - 4e-10 39.1 1.1 0.061 13.6 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ45393.1 - 1.6e-09 38.1 2.1 0.00091 19.7 0.0 4.4 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ45393.1 - 5.7e-08 32.4 10.4 0.051 13.5 0.2 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ45393.1 - 9.6e-08 31.6 2.0 0.3 10.8 0.0 5.7 2 1 4 6 6 6 3 TPR repeat TPR_6 PF13174.6 KXZ45393.1 - 0.00032 21.1 1.9 25 5.8 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ45393.1 - 0.00035 20.9 10.1 0.39 11.5 1.4 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ45393.1 - 0.00038 20.3 8.8 1.3 9.2 0.2 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ45393.1 - 0.00052 20.1 10.2 5.3 7.3 0.6 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ45393.1 - 0.00084 18.6 7.0 0.017 14.3 2.7 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ45393.1 - 0.0012 19.0 0.3 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KXZ45393.1 - 0.0084 16.3 0.1 1.6e+02 2.9 0.1 5.0 5 0 0 5 5 5 0 PPR repeat FAT PF02259.23 KXZ45393.1 - 0.0095 15.2 0.8 0.4 9.9 0.1 2.2 2 0 0 2 2 2 1 FAT domain MIT PF04212.18 KXZ45393.1 - 0.015 15.3 1.9 10 6.3 0.1 4.1 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KXZ45393.1 - 0.072 13.2 0.5 2.4 8.3 0.0 3.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 KXZ45393.1 - 0.12 12.4 0.0 3.8 7.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ45393.1 - 0.2 11.0 6.2 0.21 10.9 1.1 2.4 2 1 0 3 3 3 0 MalT-like TPR region SecE PF00584.20 KXZ45394.1 - 3.8e-14 52.4 0.3 4.5e-14 52.1 0.3 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SHIPPO-rpt PF07004.12 KXZ45395.1 - 2.3e-10 40.9 63.7 0.023 15.6 0.6 12.2 11 1 0 11 11 11 10 Sperm-tail PG-rich repeat Methyltransf_21 PF05050.12 KXZ45396.1 - 5.4e-07 29.8 0.0 5.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 KXZ45396.1 - 0.0023 17.5 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_22 PF13383.6 KXZ45397.1 - 1.1e-12 48.0 0.0 1.9e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXZ45397.1 - 1.8e-07 31.4 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain CF222 PF15661.5 KXZ45397.1 - 0.22 10.4 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 C6orf222, uncharacterised family Cpn60_TCP1 PF00118.24 KXZ45398.1 - 8.8e-134 446.8 5.1 1e-133 446.5 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 KXZ45398.1 - 0.097 13.1 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Nucleotid_trans PF03407.16 KXZ45399.1 - 6.5e-09 36.1 0.2 1.6e-08 34.8 0.2 1.6 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sec39 PF08314.11 KXZ45400.1 - 5.4e-10 38.4 0.0 0.0011 17.6 0.0 2.9 3 0 0 3 3 3 2 Secretory pathway protein Sec39 Pkinase PF00069.25 KXZ45401.1 - 0.0014 18.1 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glyco_transf_90 PF05686.12 KXZ45402.1 - 0.08 11.8 0.1 0.083 11.8 0.1 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 90 Ank_4 PF13637.6 KXZ45403.1 - 1.6e-06 28.5 0.3 0.085 13.5 0.0 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45403.1 - 1.1e-05 25.4 0.4 10 7.1 0.0 4.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 KXZ45403.1 - 0.0053 17.3 0.0 2 9.1 0.0 2.9 1 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ45403.1 - 0.29 11.5 1.6 3.7 8.0 0.1 3.2 3 1 0 3 3 3 0 Ankyrin repeats (many copies) CBM_20 PF00686.19 KXZ45404.1 - 1.1e-20 73.4 0.0 2.6e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain ATG16 PF08614.11 KXZ45404.1 - 0.0031 17.8 13.3 0.0047 17.2 13.3 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AMPK1_CBM PF16561.5 KXZ45404.1 - 0.0077 16.4 0.2 0.18 12.0 0.0 2.3 1 1 1 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Shugoshin_N PF07558.11 KXZ45404.1 - 0.039 13.8 0.4 0.13 12.2 0.4 1.9 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Atg14 PF10186.9 KXZ45404.1 - 0.044 12.9 3.4 0.061 12.4 3.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 KXZ45404.1 - 0.052 13.1 13.2 0.072 12.7 13.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein NBP1 PF08537.10 KXZ45404.1 - 0.06 12.8 3.3 0.084 12.3 3.3 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 GAS PF13851.6 KXZ45404.1 - 0.081 12.3 9.4 0.12 11.7 9.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KXZ45404.1 - 0.11 10.0 10.6 0.14 9.6 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KXZ45404.1 - 0.8 8.5 15.3 1.3 7.8 15.3 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 KXZ45404.1 - 3.7 7.3 20.2 5.1 6.8 20.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tup_N PF08581.10 KXZ45404.1 - 5 7.5 10.8 6.1 7.2 7.0 2.2 1 1 1 2 2 2 0 Tup N-terminal TSC22 PF01166.18 KXZ45404.1 - 5.9 7.3 6.6 0.56 10.6 0.6 2.4 2 2 1 3 3 3 0 TSC-22/dip/bun family ADIP PF11559.8 KXZ45404.1 - 7 6.7 14.0 1.7 8.7 4.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ribosomal_L29 PF00831.23 KXZ45404.1 - 9.5 6.3 10.4 2.7 8.0 0.7 2.5 1 1 2 3 3 3 0 Ribosomal L29 protein RMI1_N PF08585.12 KXZ45405.1 - 1.8e-29 103.1 0.6 9.4e-22 77.8 0.2 2.3 2 0 0 2 2 2 2 RecQ mediated genome instability protein Myosin_head PF00063.21 KXZ45406.1 - 1.1e-222 741.0 0.0 1.4e-222 740.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KXZ45406.1 - 0.00014 21.3 22.2 0.0033 17.1 1.8 4.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_16 PF13191.6 KXZ45406.1 - 0.02 15.3 1.8 0.058 13.8 0.0 2.7 4 0 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 KXZ45406.1 - 0.09 13.1 0.9 1.1 9.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain DnaJ PF00226.31 KXZ45407.1 - 1.2e-23 83.0 2.8 2.3e-23 82.1 2.8 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KXZ45407.1 - 3.2e-15 56.3 2.6 3.2e-15 56.3 2.6 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1977) DUF5638 PF18688.1 KXZ45407.1 - 0.0027 18.0 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5638) Bestrophin PF01062.21 KXZ45408.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Complex1_LYR PF05347.15 KXZ45409.1 - 6.3e-07 29.4 1.0 1.1e-06 28.6 1.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1664 PF07889.12 KXZ45410.1 - 0.72 9.9 5.0 3.3 7.8 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMCO5 PF14992.6 KXZ45410.1 - 5.1 6.6 13.4 62 3.0 13.5 2.3 1 1 0 1 1 1 0 TMCO5 family Sulfotransfer_3 PF13469.6 KXZ45411.1 - 7.7e-06 26.4 2.2 0.21 12.0 0.0 3.5 3 1 0 4 4 4 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KXZ45411.1 - 0.00031 20.3 0.0 0.0014 18.2 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_transf_90 PF05686.12 KXZ45412.1 - 2.3e-14 53.2 0.1 1.9e-13 50.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 90 SelB-wing_2 PF09106.11 KXZ45413.1 - 0.012 15.8 0.8 0.044 14.0 0.8 2.0 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Gly_rich PF12810.7 KXZ45414.1 - 0.03 14.2 1.0 0.045 13.7 1.0 1.2 1 0 0 1 1 1 0 Glycine rich protein DUF5585 PF17823.1 KXZ45414.1 - 8.9 5.1 10.5 14 4.5 10.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Sulfotransfer_1 PF00685.27 KXZ45415.1 - 0.0012 18.3 0.1 1.3 8.4 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ45415.1 - 0.0034 17.8 0.2 0.74 10.2 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family NAP PF00956.18 KXZ45416.1 - 7.4e-80 268.0 1.0 1.1e-79 267.4 1.0 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) OmpH PF03938.14 KXZ45416.1 - 0.0082 16.5 3.6 0.039 14.3 3.2 2.1 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Phage_Mu_Gam PF07352.12 KXZ45416.1 - 0.044 13.7 1.0 0.11 12.4 1.0 1.7 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Snapin_Pallidin PF14712.6 KXZ45416.1 - 0.085 13.3 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Snapin/Pallidin BSD PF03909.17 KXZ45416.1 - 0.19 11.8 0.7 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 BSD domain M PF02370.16 KXZ45416.1 - 1.6 9.6 6.3 5.1 8.0 0.1 3.1 2 0 0 2 2 2 0 M protein repeat FliJ PF02050.16 KXZ45417.1 - 0.014 15.7 9.4 0.014 15.7 9.4 7.3 5 2 3 8 8 8 0 Flagellar FliJ protein DUF3983 PF13137.6 KXZ45417.1 - 0.04 13.7 0.7 0.18 11.6 0.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) FlaC_arch PF05377.11 KXZ45417.1 - 0.052 13.9 0.3 0.052 13.9 0.3 6.2 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) EF-hand_1 PF00036.32 KXZ45419.1 - 1.2e-11 43.3 1.4 9.5e-05 21.7 1.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXZ45419.1 - 1.4e-10 41.5 0.0 2.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ45419.1 - 2.7e-09 36.1 1.7 0.0021 17.5 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXZ45419.1 - 9.1e-08 31.5 0.2 0.0021 17.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KXZ45419.1 - 1.6e-07 31.1 0.2 4.7e-07 29.6 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair MA3 PF02847.17 KXZ45420.1 - 1.6e-11 44.2 0.0 3.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KXZ45420.1 - 2.1e-09 37.4 0.0 3.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain PaO PF08417.12 KXZ45421.1 - 1.5e-20 73.2 0.0 2.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske PF00355.26 KXZ45421.1 - 0.00015 21.6 0.1 0.0003 20.7 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAM199X PF15814.5 KXZ45421.1 - 6.8 5.6 5.3 12 4.8 5.3 1.4 1 0 0 1 1 1 0 Protein family FAM199X Heme_oxygenase PF01126.20 KXZ45422.1 - 2.1e-16 60.4 0.1 2.2e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Heme oxygenase Peptidase_M60 PF13402.6 KXZ45424.1 - 9.7e-55 186.0 0.0 1.3e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 KXZ45424.1 - 8.1e-16 57.9 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Pkinase PF00069.25 KXZ45426.1 - 7.9e-25 87.7 0.0 4.5e-14 52.4 0.0 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45426.1 - 1.3e-12 47.6 0.0 2.4e-06 27.1 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ45426.1 - 0.0096 15.9 0.1 0.66 9.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Glyco_transf_90 PF05686.12 KXZ45427.1 - 2.3e-24 86.1 0.0 3.1e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXZ45427.1 - 0.003 17.9 0.0 0.0052 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Chloroa_b-bind PF00504.21 KXZ45429.1 - 0.008 16.7 0.0 0.013 16.0 0.0 1.4 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Peptidase_S10 PF00450.22 KXZ45430.1 - 4.6e-119 398.5 0.0 5.7e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2632 PF10943.8 KXZ45430.1 - 0.064 12.8 1.2 0.27 10.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2632) TTL PF03133.15 KXZ45431.1 - 1.2e-19 70.6 0.0 4.6e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KXZ45431.1 - 0.13 11.5 0.0 0.33 10.2 0.0 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Phage_integrase PF00589.22 KXZ45432.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 2 0 0 2 2 2 0 Phage integrase family Aldo_ket_red PF00248.21 KXZ45433.1 - 3.1e-22 79.1 0.0 2.6e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Aldo/keto reductase family UQ_con PF00179.26 KXZ45434.1 - 3.5e-24 85.1 0.0 5.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KXZ45434.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain PP2C PF00481.21 KXZ45435.1 - 1.5e-31 110.0 0.0 2.4e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 KXZ45435.1 - 5.5e-15 55.5 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXZ45435.1 - 5.7e-07 29.8 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SMN PF06003.12 KXZ45435.1 - 0.021 14.1 1.2 0.037 13.3 1.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Glyco_transf_90 PF05686.12 KXZ45436.1 - 1.6e-25 89.9 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 PfkB PF00294.24 KXZ45438.1 - 8.7e-30 104.0 3.4 2e-11 43.8 0.0 3.3 3 0 0 3 3 3 3 pfkB family carbohydrate kinase AP_endonuc_2 PF01261.24 KXZ45438.1 - 9e-15 54.7 0.1 2.3e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Phos_pyr_kin PF08543.12 KXZ45438.1 - 0.00056 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1995 PF09353.10 KXZ45439.1 - 1.5e-37 129.5 0.0 1.9e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Ribosomal_L14 PF00238.19 KXZ45440.1 - 1.4e-36 125.2 0.1 1.7e-36 124.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Bap31_Bap29_C PF18035.1 KXZ45441.1 - 5.9e-10 39.0 4.0 5.9e-10 39.0 4.0 4.1 3 1 0 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain FHA PF00498.26 KXZ45441.1 - 9.1e-08 32.3 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain FYVE_2 PF02318.16 KXZ45441.1 - 3.3 7.9 3.9 11 6.3 3.9 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger HlyIII PF03006.20 KXZ45442.1 - 6.8e-20 71.7 11.2 8e-20 71.5 11.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.25 KXZ45443.1 - 8.6e-73 244.9 0.0 8.8e-56 189.2 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45443.1 - 2e-36 125.6 0.0 1.5e-32 112.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 KXZ45443.1 - 2.5e-09 36.8 0.1 5.9e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KXZ45443.1 - 5.2e-06 26.0 0.0 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KXZ45443.1 - 0.00056 19.6 0.7 0.0011 18.6 0.7 1.4 1 0 0 1 1 1 1 RIO1 family UBA PF00627.31 KXZ45443.1 - 0.00068 19.5 0.1 0.0012 18.7 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain AdenylateSensor PF16579.5 KXZ45443.1 - 0.041 14.3 0.2 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 Adenylate sensor of SNF1-like protein kinase UBA_3 PF09288.10 KXZ45443.1 - 0.069 13.0 1.2 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain UBA_2 PF08587.11 KXZ45443.1 - 0.083 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) ABC1 PF03109.16 KXZ45443.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family YukC PF10140.9 KXZ45443.1 - 0.17 10.7 0.1 0.32 9.8 0.1 1.4 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 KXZ45443.1 - 0.19 10.7 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Laminin_G_3 PF13385.6 KXZ45444.1 - 1.6e-12 47.8 0.5 6.5e-12 45.9 0.1 2.3 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily NmrA PF05368.13 KXZ45445.1 - 1.4e-22 80.4 0.0 1.8e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXZ45445.1 - 1.1e-11 45.0 1.8 1.5e-11 44.5 1.8 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXZ45445.1 - 0.004 16.2 0.0 0.006 15.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.25 KXZ45446.1 - 1.4e-43 149.1 0.0 1e-42 146.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45446.1 - 5.5e-13 48.8 0.0 1.1e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase HABP4_PAI-RBP1 PF04774.15 KXZ45447.1 - 3.3e-14 53.7 15.5 3.3e-14 53.7 15.5 3.2 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 KXZ45447.1 - 1.9e-11 44.6 6.7 1.9e-11 44.6 6.7 5.1 4 2 1 6 6 6 1 Stm1 LDcluster4 PF18306.1 KXZ45448.1 - 2.6e-24 85.6 2.0 6.2e-24 84.4 2.0 1.6 1 0 0 1 1 1 1 SLOG cluster4 family Glycos_transf_2 PF00535.26 KXZ45448.1 - 1.3e-09 38.1 0.0 0.0059 16.4 0.0 3.5 3 0 0 3 3 3 3 Glycosyl transferase family 2 Lysine_decarbox PF03641.14 KXZ45448.1 - 0.025 14.7 0.1 0.051 13.7 0.1 1.4 1 0 0 1 1 1 0 Possible lysine decarboxylase Glyco_tranf_2_3 PF13641.6 KXZ45448.1 - 0.13 12.1 6.3 1.9 8.3 0.0 4.4 5 0 0 5 5 5 0 Glycosyltransferase like family 2 Methyltransf_12 PF08242.12 KXZ45448.1 - 0.15 12.8 0.0 0.39 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UTP25 PF06862.12 KXZ45449.1 - 2.2e-137 458.7 0.0 4.8e-137 457.6 0.0 1.4 1 1 1 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SDA1 PF05285.12 KXZ45449.1 - 0.31 10.4 12.3 0.52 9.7 12.3 1.3 1 0 0 1 1 1 0 SDA1 PRR18 PF15671.5 KXZ45450.1 - 1.5 8.6 10.4 2.4 8.0 10.4 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 CLZ PF16526.5 KXZ45453.1 - 0.023 15.0 2.9 0.023 15.0 2.9 5.0 3 3 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MPS2 PF17060.5 KXZ45453.1 - 0.75 9.0 5.2 1.4 8.1 5.2 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 RINGv PF12906.7 KXZ45454.1 - 5.2e-06 26.5 6.7 7.9e-06 25.9 6.7 1.3 1 0 0 1 1 1 1 RING-variant domain TMEM208_SND2 PF05620.11 KXZ45454.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 zf-RING_2 PF13639.6 KXZ45454.1 - 0.84 10.0 5.8 1.4 9.3 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain MscS_TM PF12794.7 KXZ45454.1 - 7.8 5.2 7.9 13 4.6 7.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 OTU PF02338.19 KXZ45455.1 - 1.7e-13 51.2 0.0 2.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXZ45455.1 - 0.066 12.7 0.1 9.1 5.6 0.0 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain Ribosomal_L7Ae PF01248.26 KXZ45456.1 - 9.6e-30 102.2 2.0 1.2e-29 101.9 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RPA_interact_C PF14768.6 KXZ45456.1 - 0.21 12.2 3.6 0.34 11.5 0.0 2.2 2 1 0 2 2 2 0 Replication protein A interacting C-terminal GDP_Man_Dehyd PF16363.5 KXZ45457.1 - 1.1e-43 150.0 0.0 1.2e-43 149.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXZ45457.1 - 1.2e-34 119.8 0.0 1.5e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ45457.1 - 1.5e-16 60.3 0.1 1.7e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXZ45457.1 - 1.3e-13 50.7 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXZ45457.1 - 1.7e-09 37.2 0.0 2.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KXZ45457.1 - 2.9e-07 30.6 0.0 4.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXZ45457.1 - 3.7e-07 29.8 0.0 4.4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KXZ45457.1 - 0.00031 20.7 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXZ45457.1 - 0.00034 19.9 0.1 0.00075 18.7 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KXZ45457.1 - 0.00041 20.6 0.0 0.00069 19.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KXZ45457.1 - 0.002 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_12 PF08242.12 KXZ45457.1 - 0.0052 17.5 0.0 0.0076 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ45457.1 - 0.013 16.2 0.0 0.02 15.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.27 KXZ45457.1 - 0.032 14.8 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXZ45457.1 - 0.038 14.4 0.0 0.047 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KXZ45457.1 - 0.042 13.7 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXZ45458.1 - 1.5e-12 47.6 0.0 2.3e-12 47.0 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXZ45458.1 - 1.3e-07 31.4 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RNase_PH PF01138.21 KXZ45459.1 - 5.7e-38 130.4 0.0 8.3e-20 71.6 0.0 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXZ45459.1 - 2.2e-11 43.6 0.0 8.4e-06 25.7 0.0 2.9 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.14 KXZ45459.1 - 7.1e-11 42.5 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 KXZ45459.1 - 3e-08 33.9 0.0 6.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 KXZ45459.1 - 3.9e-06 26.6 0.0 8.3e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KXZ45459.1 - 0.0018 18.1 0.1 0.0043 16.9 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KXZ45459.1 - 0.011 15.6 0.1 0.025 14.4 0.1 1.6 1 0 0 1 1 1 0 KH domain Pkinase PF00069.25 KXZ45461.1 - 1e-49 169.3 0.0 2.6e-41 141.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45461.1 - 6.3e-21 74.8 0.0 2.9e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXZ45461.1 - 0.073 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RRM_1 PF00076.22 KXZ45462.1 - 5.6e-43 144.6 0.1 1.2e-17 63.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXZ45462.1 - 1.6e-15 57.9 0.0 5.5e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM PF05172.13 KXZ45462.1 - 4.6e-06 26.5 0.0 0.11 12.4 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXZ45462.1 - 5.8e-06 25.9 0.2 0.096 12.3 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 KXZ45462.1 - 0.0037 17.1 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KXZ45462.1 - 0.016 15.2 0.1 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Ret2_MD PF18528.1 KXZ45462.1 - 0.21 12.0 1.5 2.5 8.6 0.1 2.8 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Telomerase_RBD PF12009.8 KXZ45463.1 - 4.5e-35 120.7 0.0 5.9e-34 117.0 0.0 2.3 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KXZ45463.1 - 4.7e-08 32.8 0.0 0.0021 17.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Thi4 PF01946.17 KXZ45464.1 - 5e-106 353.2 0.9 6.2e-106 352.9 0.9 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXZ45464.1 - 1.3e-05 24.9 3.3 8.2e-05 22.3 0.9 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ45464.1 - 1.7e-05 24.1 3.4 0.00049 19.3 1.3 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXZ45464.1 - 2.8e-05 23.5 0.1 3.9e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXZ45464.1 - 5.8e-05 23.2 0.5 0.0002 21.5 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXZ45464.1 - 0.0014 17.8 0.6 0.0014 17.8 0.6 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXZ45464.1 - 0.018 15.0 0.1 0.018 15.0 0.1 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 KXZ45464.1 - 0.036 13.1 0.5 0.34 10.0 0.6 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXZ45464.1 - 0.038 12.7 1.4 0.054 12.2 1.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXZ45464.1 - 0.04 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RTP1_C2 PF10304.9 KXZ45464.1 - 0.11 12.3 0.6 0.5 10.1 0.2 2.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Phage_lysis PF03245.13 KXZ45465.1 - 0.059 13.5 0.1 0.27 11.4 0.1 2.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Brix PF04427.18 KXZ45466.1 - 4.6e-33 114.9 0.1 4.6e-33 114.9 0.1 1.7 2 0 0 2 2 2 1 Brix domain SR-25 PF10500.9 KXZ45466.1 - 0.00067 19.3 11.6 0.00067 19.3 11.6 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CSRNP_N PF16019.5 KXZ45466.1 - 0.043 13.7 0.9 0.086 12.8 0.9 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus PRP3 PF08572.10 KXZ45466.1 - 0.81 9.4 11.2 0.11 12.2 3.8 2.2 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Bac_globin PF01152.21 KXZ45467.1 - 1.3e-07 31.8 0.0 2.1e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Bacterial-like globin Bac_globin PF01152.21 KXZ45468.1 - 0.0033 17.6 0.0 0.0061 16.7 0.0 1.4 1 1 0 1 1 1 1 Bacterial-like globin eIF-1a PF01176.19 KXZ45469.1 - 2.4e-22 78.5 0.1 3.3e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 KXZ45469.1 - 4e-06 26.5 0.1 5.7e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 RsgA N-terminal domain Myosin_N PF02736.19 KXZ45469.1 - 0.043 13.7 0.2 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Mito_carr PF00153.27 KXZ45470.1 - 3.5e-33 113.4 1.3 2.8e-19 68.8 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Exostosin PF03016.15 KXZ45471.1 - 3.1e-29 102.1 0.0 2.2e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 Exostosin family EGF_Tenascin PF18720.1 KXZ45471.1 - 4.6 7.4 17.9 1.3 9.2 9.7 2.6 2 0 0 2 2 2 0 Tenascin EGF domain RAP PF08373.10 KXZ45472.1 - 4.1e-06 26.8 0.0 8.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RAP domain RAP PF08373.10 KXZ45473.1 - 3.5e-06 27.0 0.0 6.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RAP domain Senescence PF06911.12 KXZ45474.1 - 1.2e-25 90.9 13.1 1.2e-25 90.9 13.1 2.0 1 1 1 2 2 2 1 Senescence-associated protein SPRY PF00622.28 KXZ45475.1 - 1.7e-17 63.6 0.0 2.6e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KXZ45475.1 - 0.044 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 LisH Nucleoside_tran PF01733.18 KXZ45476.1 - 3.1e-06 26.8 5.2 3.1e-06 26.8 5.2 1.7 2 0 0 2 2 2 1 Nucleoside transporter Chloroa_b-bind PF00504.21 KXZ45477.1 - 8.9e-12 45.8 2.6 2.1e-10 41.3 1.7 2.2 1 1 0 1 1 1 1 Chlorophyll A-B binding protein MgtC PF02308.16 KXZ45477.1 - 0.024 15.0 1.9 0.046 14.1 1.9 1.4 1 0 0 1 1 1 0 MgtC family DUF1427 PF07235.11 KXZ45477.1 - 5.9 6.9 7.0 7.7 6.5 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1427) Nucleotid_trans PF03407.16 KXZ45478.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Pkinase PF00069.25 KXZ45478.1 - 0.0028 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Trep_Strep PF09605.10 KXZ45478.1 - 0.019 14.9 0.3 0.035 14.1 0.3 1.3 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) SMN PF06003.12 KXZ45478.1 - 0.67 9.2 5.0 1.7 7.8 5.0 1.6 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ank_2 PF12796.7 KXZ45479.1 - 3.3e-15 56.4 4.3 4.1e-05 24.1 0.0 4.5 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45479.1 - 1.3e-10 41.5 9.3 0.15 12.7 0.6 7.3 4 3 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45479.1 - 7.1e-07 29.1 9.0 5.9 7.8 0.0 8.0 10 0 0 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 KXZ45479.1 - 0.00021 21.5 8.5 0.21 11.9 0.1 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ad_Cy_reg PF16701.5 KXZ45479.1 - 0.05 13.3 0.7 4.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Adenylate cyclase regulatory domain SelP_N PF04592.14 KXZ45479.1 - 0.3 10.4 15.1 0.5 9.7 15.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF515 PF04415.12 KXZ45480.1 - 2.7 6.3 4.4 3.7 5.8 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MRAP PF15183.6 KXZ45481.1 - 0.044 13.7 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF2207 PF09972.9 KXZ45481.1 - 2.5 6.7 3.8 2.8 6.6 3.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FAM199X PF15814.5 KXZ45482.1 - 0.29 10.2 0.1 0.46 9.5 0.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF2252 PF10009.9 KXZ45483.1 - 6.9e-73 246.0 6.8 2.5e-37 128.9 0.6 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2252) PRP1_N PF06424.12 KXZ45483.1 - 0.056 13.8 0.6 0.12 12.8 0.6 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Nucleotid_trans PF03407.16 KXZ45484.1 - 4.9e-05 23.4 0.0 6.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Exo_endo_phos PF03372.23 KXZ45485.1 - 3.3e-16 59.5 3.5 4.1e-07 29.7 1.8 3.0 3 0 0 3 3 3 2 Endonuclease/Exonuclease/phosphatase family DUF3450 PF11932.8 KXZ45487.1 - 0.016 14.5 3.2 0.024 14.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ABC_trans_aux PF03886.13 KXZ45487.1 - 0.02 14.5 0.1 0.055 13.0 0.1 1.7 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component Fez1 PF06818.15 KXZ45487.1 - 0.021 15.3 2.7 0.041 14.3 2.7 1.4 1 0 0 1 1 1 0 Fez1 UPF0242 PF06785.11 KXZ45487.1 - 0.11 12.6 1.7 0.18 11.9 1.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus IFT20 PF14931.6 KXZ45487.1 - 0.15 12.2 3.0 0.33 11.2 3.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 JAKMIP_CC3 PF16034.5 KXZ45487.1 - 1.1 9.2 8.7 0.53 10.2 5.0 1.9 2 0 0 2 2 2 0 JAKMIP CC3 domain APG6_N PF17675.1 KXZ45487.1 - 1.2 9.6 8.0 0.29 11.7 3.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Iso_dh PF00180.20 KXZ45488.1 - 1.2e-79 268.0 0.0 1.4e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-DNA_Pol PF08996.10 KXZ45491.1 - 0.0044 16.8 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger Hint PF01079.20 KXZ45492.1 - 1.5e-17 63.9 0.0 2.8e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Hint module EF-hand_5 PF13202.6 KXZ45492.1 - 0.022 14.2 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KXZ45492.1 - 0.08 12.5 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF4006 PF13179.6 KXZ45492.1 - 0.2 11.6 0.5 0.42 10.6 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Ank_2 PF12796.7 KXZ45493.1 - 3.9e-05 24.2 0.0 0.00018 22.0 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45493.1 - 0.0053 17.2 0.0 30 5.6 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat FA_hydroxylase PF04116.13 KXZ45494.1 - 2.2e-09 37.8 5.5 5e-09 36.6 4.7 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2231 PF09990.9 KXZ45494.1 - 0.016 15.6 0.3 0.033 14.6 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) PgpA PF04608.13 KXZ45494.1 - 0.058 13.4 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A DUF2721 PF11026.8 KXZ45494.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Glyco_transf_5 PF08323.11 KXZ45496.1 - 4.1e-17 62.7 0.3 7.6e-17 61.8 0.1 1.5 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXZ45496.1 - 7e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ45496.1 - 1.9e-05 25.1 0.0 3.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ45496.1 - 0.073 13.1 0.4 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXZ45496.1 - 0.77 10.2 7.6 0.13 12.7 2.6 2.2 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain WD40 PF00400.32 KXZ45497.1 - 1.1e-09 38.7 1.3 0.012 16.5 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat ABC1 PF03109.16 KXZ45498.1 - 8.3e-32 109.9 0.0 1.5e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXZ45498.1 - 6.6e-07 29.5 0.0 2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ45498.1 - 0.0016 17.9 0.0 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DUF1664 PF07889.12 KXZ45499.1 - 0.1 12.6 0.2 0.36 10.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) WD40 PF00400.32 KXZ45500.1 - 8.1e-15 55.0 4.3 0.0037 18.1 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.6 KXZ45500.1 - 0.01 16.3 3.4 59 4.3 0.0 4.8 5 0 0 5 5 5 0 PQQ-like domain Frtz PF11768.8 KXZ45500.1 - 0.012 14.0 0.0 0.1 10.9 0.0 2.2 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 KXZ45500.1 - 0.18 12.2 0.0 9.5 6.6 0.0 3.4 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TPMT PF05724.11 KXZ45501.1 - 2.4e-30 105.8 0.0 2.8e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KXZ45501.1 - 2.1e-05 25.2 0.0 3.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ45501.1 - 0.0041 17.7 0.0 0.018 15.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ45501.1 - 0.016 15.0 0.0 0.062 13.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ45501.1 - 0.046 14.5 0.0 0.21 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Nse4_C PF08743.10 KXZ45502.1 - 2.1e-21 76.0 0.2 8.4e-21 74.0 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal ERO1 PF04137.15 KXZ45502.1 - 0.024 13.8 0.2 0.032 13.4 0.2 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Nckap1 PF09735.9 KXZ45503.1 - 7.8e-20 70.5 0.0 2.9e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 Membrane-associated apoptosis protein Arm PF00514.23 KXZ45504.1 - 3.1e-89 290.6 12.0 3.7e-13 49.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KXZ45504.1 - 6.9e-22 76.8 3.8 1.1e-21 76.2 0.5 2.6 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KXZ45504.1 - 7.5e-22 77.4 0.6 1.5e-09 38.2 0.0 5.3 4 2 3 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 KXZ45504.1 - 5.7e-20 71.5 0.0 6.1e-09 36.1 0.0 5.0 3 2 2 5 5 5 4 HEAT repeats IBB PF01749.20 KXZ45504.1 - 4.4e-19 68.7 0.6 9.4e-19 67.7 0.6 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 KXZ45504.1 - 4.5e-12 45.1 0.4 2.9e-05 24.0 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.13 KXZ45504.1 - 4.7e-08 32.8 0.0 0.35 10.3 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.8 KXZ45504.1 - 1.9e-05 24.7 0.0 2.7 8.1 0.0 4.3 3 2 2 5 5 5 3 V-ATPase subunit H HEAT_PBS PF03130.16 KXZ45504.1 - 0.00014 22.2 0.1 0.15 12.8 0.0 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 KXZ45504.1 - 0.00042 20.5 0.2 4.3 7.6 0.0 4.8 3 1 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 KXZ45504.1 - 0.0011 17.7 0.0 0.027 13.0 0.0 2.8 1 1 2 3 3 3 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 KXZ45504.1 - 0.0014 18.6 0.1 0.83 9.7 0.0 2.9 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Pro_isomerase PF00160.21 KXZ45505.1 - 1.2e-42 145.8 0.0 4.1e-42 144.1 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SDA1 PF05285.12 KXZ45505.1 - 0.042 13.3 10.6 0.29 10.5 0.4 2.4 2 0 0 2 2 2 0 SDA1 Patatin PF01734.22 KXZ45507.1 - 0.00024 21.3 0.3 0.0011 19.2 0.3 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase POPLD PF08170.12 KXZ45508.1 - 9e-17 61.2 0.2 2.3e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 POPLD (NUC188) domain Peptidase_C1 PF00112.23 KXZ45509.1 - 4.1e-43 148.0 5.1 9.8e-39 133.7 0.8 2.4 1 1 1 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 KXZ45509.1 - 8.8e-09 35.7 0.1 1.7e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PaaX_C PF08223.11 KXZ45509.1 - 0.047 14.0 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Folliculin PF11704.8 KXZ45509.1 - 0.6 10.0 2.0 1.9 8.4 0.1 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport SF-assemblin PF06705.11 KXZ45510.1 - 1e-105 352.6 16.7 1.2e-105 352.4 16.7 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF4795 PF16043.5 KXZ45510.1 - 0.0012 18.5 13.9 0.0017 18.0 13.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) SHNi-TPR PF10516.9 KXZ45510.1 - 0.016 14.6 0.9 6.9 6.2 0.1 3.0 2 0 0 2 2 2 0 SHNi-TPR Baculo_gp64 PF03273.13 KXZ45510.1 - 0.16 10.7 0.6 0.26 10.1 0.6 1.4 1 1 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Baculo_PEP_C PF04513.12 KXZ45510.1 - 0.24 11.5 6.3 0.34 10.9 1.9 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KXZ45510.1 - 0.25 10.6 12.2 0.14 11.5 9.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GCN5L1 PF06320.13 KXZ45510.1 - 0.68 10.1 18.5 3.1 8.0 9.5 3.2 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) Gp58 PF07902.11 KXZ45510.1 - 1.3 7.2 9.4 0.83 7.9 7.6 1.5 1 1 0 1 1 1 0 gp58-like protein Syntaxin-6_N PF09177.11 KXZ45510.1 - 2.8 8.6 14.7 0.35 11.4 4.7 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF1690 PF07956.11 KXZ45510.1 - 3.5 8.1 21.7 70 3.8 17.6 3.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) MIF4G PF02854.19 KXZ45511.1 - 0.00027 20.7 0.0 0.031 13.9 0.0 2.9 2 1 0 2 2 2 1 MIF4G domain TetR_C_32 PF09209.11 KXZ45511.1 - 0.47 10.5 2.6 9.3 6.3 0.1 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain RCC1 PF00415.18 KXZ45514.1 - 8.5e-56 186.4 15.3 6e-14 52.4 0.2 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ45514.1 - 1.1e-12 47.4 36.6 7.5e-05 22.4 2.2 7.3 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Spt20 PF12090.8 KXZ45515.1 - 5.9 6.4 9.7 10 5.6 9.7 1.4 1 0 0 1 1 1 0 Spt20 family SET PF00856.28 KXZ45516.1 - 3.1e-12 47.2 0.0 8.2e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 SET domain DUF5375 PF17345.2 KXZ45519.1 - 1.1 9.2 4.6 0.39 10.6 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5375) Pkinase PF00069.25 KXZ45522.1 - 4.9e-12 45.8 0.0 8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45522.1 - 0.005 16.1 0.0 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXZ45522.1 - 0.18 11.7 7.9 0.074 13.0 4.3 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family SelP_N PF04592.14 KXZ45522.1 - 7.2 5.9 7.3 12 5.2 7.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FMO-like PF00743.19 KXZ45523.1 - 3.1e-30 105.1 0.0 1.4e-12 46.9 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXZ45523.1 - 6.4e-11 42.1 0.0 5.2e-09 35.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ45523.1 - 6e-09 35.5 0.0 4.9e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXZ45523.1 - 1.9e-08 33.9 4.5 7.6e-06 25.4 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXZ45523.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SUIM_assoc PF16619.5 KXZ45523.1 - 8 6.6 7.1 25 5.0 7.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Gly_rich PF12810.7 KXZ45524.1 - 0.23 11.4 16.8 0.36 10.7 16.8 1.3 1 0 0 1 1 1 0 Glycine rich protein EGF_2 PF07974.13 KXZ45525.1 - 0.0025 18.2 10.9 0.0025 18.2 10.9 7.5 5 1 2 7 7 7 4 EGF-like domain Mem_trans PF03547.18 KXZ45527.1 - 2.2e-06 26.3 13.2 2.3e-06 26.3 2.3 2.2 2 0 0 2 2 2 2 Membrane transport protein TFIIA PF03153.13 KXZ45527.1 - 0.14 12.1 14.0 0.2 11.6 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Radical_SAM PF04055.21 KXZ45529.1 - 2.7e-19 70.1 0.0 2.4e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 Radical SAM superfamily EB1 PF03271.17 KXZ45530.1 - 1.7e-16 60.2 0.8 3.7e-16 59.1 0.8 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KXZ45530.1 - 1.1e-11 44.9 0.1 2.1e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KXZ45530.1 - 0.00021 21.4 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KXZ45530.1 - 0.0014 18.4 0.2 0.003 17.3 0.2 1.5 1 0 0 1 1 1 1 CAMSAP CH domain DUF502 PF04367.13 KXZ45531.1 - 1.5e-28 98.8 1.0 2.1e-28 98.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF502) DUF572 PF04502.13 KXZ45532.1 - 1.2e-71 242.1 0.0 1.9e-71 241.4 0.0 1.3 2 0 0 2 2 2 1 Family of unknown function (DUF572) C1_4 PF07975.12 KXZ45532.1 - 0.021 15.1 1.8 0.17 12.1 0.4 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 KXZ45532.1 - 0.059 13.6 1.0 0.1 12.8 1.0 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 KXZ45532.1 - 1.2 9.3 4.7 3.5 7.9 1.6 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger DNA_RNApol_7kD PF03604.13 KXZ45532.1 - 3.2 7.5 6.4 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PDEase_I PF00233.19 KXZ45534.1 - 5.3e-28 98.4 0.0 7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Metallothio_Pro PF02069.16 KXZ45535.1 - 1 9.7 4.4 0.55 10.5 0.6 2.2 2 0 0 2 2 2 0 Prokaryotic metallothionein UPF0172 PF03665.13 KXZ45538.1 - 4.6e-53 180.1 0.0 5.2e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 KXZ45538.1 - 2.1e-06 27.7 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Peptidase_C78 PF07910.13 KXZ45539.1 - 2.8e-48 164.2 0.0 2.8e-33 115.2 0.0 2.9 2 1 0 2 2 2 2 Peptidase family C78 ZZ PF00569.17 KXZ45539.1 - 7.3e-08 32.1 0.1 1.4e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-CCHC PF00098.23 KXZ45539.1 - 9.2e-07 28.7 1.5 2.2e-06 27.5 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KXZ45539.1 - 0.0017 18.3 0.1 0.0041 17.1 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 KXZ45539.1 - 0.011 16.1 0.1 0.042 14.2 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.6 KXZ45539.1 - 0.023 14.5 1.1 0.023 14.5 1.1 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 KXZ45539.1 - 0.13 12.0 2.9 0.28 10.9 2.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Peptidase_C54 PF03416.19 KXZ45539.1 - 0.13 11.6 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C54 Methyltransf_2 PF00891.18 KXZ45540.1 - 1.6e-24 86.4 0.0 1.9e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXZ45540.1 - 0.0014 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Rtf2 PF04641.12 KXZ45541.1 - 1e-56 192.2 0.0 1.3e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger ubiquitin PF00240.23 KXZ45541.1 - 0.0023 17.7 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DnaJ PF00226.31 KXZ45543.1 - 5.1e-24 84.2 1.8 1.2e-23 83.0 1.8 1.7 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 KXZ45543.1 - 1.5e-10 41.1 4.9 1.1e-07 32.0 1.4 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXZ45543.1 - 1.5e-10 41.0 4.6 4.5e-10 39.5 1.6 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXZ45543.1 - 6e-08 32.9 2.2 0.013 16.3 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXZ45543.1 - 1.2e-06 28.6 8.3 0.011 16.1 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KXZ45543.1 - 1.8e-06 28.2 4.2 0.016 15.6 0.4 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KXZ45543.1 - 0.0036 17.2 8.4 0.062 13.3 0.5 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 KXZ45543.1 - 0.0046 17.4 0.1 1.3 9.6 0.1 3.1 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KXZ45543.1 - 0.061 14.0 0.3 16 6.1 0.1 2.8 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats PIN_10 PF18478.1 KXZ45543.1 - 0.064 13.5 1.0 0.19 12.0 1.0 1.8 1 0 0 1 1 1 0 PIN like domain zf-CpG_bind_C PF12269.8 KXZ45543.1 - 6.8 6.4 15.2 0.68 9.7 7.9 2.8 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain Reprolysin_5 PF13688.6 KXZ45544.1 - 1.3e-05 25.4 0.2 2.5e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 KXZ45544.1 - 2.1e-05 24.5 3.5 2.1e-05 24.5 0.5 2.4 3 0 0 3 3 3 1 Pregnancy-associated plasma protein-A SRCR PF00530.18 KXZ45545.1 - 8.2e-11 42.3 0.1 2.3e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Syndecan PF01034.20 KXZ45545.1 - 0.22 11.4 3.3 0.45 10.5 3.3 1.5 1 0 0 1 1 1 0 Syndecan domain Peptidase_M43 PF05572.13 KXZ45546.1 - 1.4e-06 28.3 0.1 3.9e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXZ45546.1 - 0.0039 17.4 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_5 PF13688.6 KXZ45547.1 - 0.00071 19.8 0.7 0.0012 19.0 0.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 KXZ45547.1 - 0.0072 16.2 0.1 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A MGC-24 PF05283.11 KXZ45548.1 - 0.29 11.6 5.9 0.62 10.5 6.0 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Reprolysin_5 PF13688.6 KXZ45549.1 - 7e-06 26.3 0.1 3.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 KXZ45549.1 - 3.8e-05 23.6 0.2 0.0001 22.2 0.2 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 KXZ45549.1 - 0.048 13.3 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M90 PF06167.12 KXZ45549.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Reprolysin_3 PF13582.6 KXZ45549.1 - 0.16 12.5 0.4 0.36 11.4 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Ribosomal_L7Ae PF01248.26 KXZ45550.1 - 2.7e-26 91.1 0.0 3.3e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KXZ45550.1 - 0.00031 20.6 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain ThiC_Rad_SAM PF01964.18 KXZ45552.1 - 3.5e-193 642.1 0.0 4.2e-193 641.8 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 KXZ45552.1 - 1.3e-09 37.8 0.1 3.7e-09 36.3 0.1 1.8 1 1 0 1 1 1 1 ThiC-associated domain DUF2322 PF10084.9 KXZ45553.1 - 5.9e-13 48.7 0.0 6.3e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2322) DUF2322 PF10084.9 KXZ45554.1 - 3.5e-10 39.8 0.0 4e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2322) MEDS PF14417.6 KXZ45554.1 - 0.045 13.6 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Cnd1 PF12717.7 KXZ45555.1 - 2.3e-23 83.0 0.4 3e-19 69.7 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KXZ45555.1 - 6.3e-06 25.6 0.0 8.1e-05 22.0 0.0 2.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KXZ45555.1 - 0.0022 18.4 2.5 0.029 14.7 0.3 5.2 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KXZ45555.1 - 0.0037 17.4 36.9 0.85 10.0 0.2 9.8 11 0 0 11 11 11 3 HEAT repeat Adaptin_N PF01602.20 KXZ45555.1 - 0.0092 14.6 0.3 0.071 11.7 0.1 2.1 2 0 0 2 2 2 1 Adaptin N terminal region Cohesin_HEAT PF12765.7 KXZ45555.1 - 0.036 14.4 10.5 0.64 10.4 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 KXZ45555.1 - 0.69 9.6 5.4 3.8 7.2 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) ABC_tran PF00005.27 KXZ45556.1 - 4.2e-24 85.6 0.0 1.1e-23 84.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ45556.1 - 0.00011 22.1 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXZ45556.1 - 0.0012 18.8 0.2 0.0035 17.3 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 KXZ45556.1 - 0.0026 17.7 0.2 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KXZ45556.1 - 0.01 16.1 1.5 0.097 12.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KXZ45556.1 - 0.013 15.1 0.0 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ45556.1 - 0.015 15.7 0.1 0.072 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KXZ45556.1 - 0.041 14.3 0.1 0.15 12.5 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KXZ45556.1 - 0.045 13.2 0.0 4.2 6.7 0.0 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXZ45556.1 - 0.055 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ45556.1 - 0.09 13.3 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain OSCP PF00213.18 KXZ45556.1 - 0.51 10.4 3.0 18 5.4 2.3 2.4 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit LSM PF01423.22 KXZ45557.1 - 5e-21 74.2 0.0 6.3e-21 73.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXZ45557.1 - 0.011 15.8 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM PF01423.22 KXZ45558.1 - 1.1e-17 63.4 0.0 1.4e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain SpoIIIAH PF12685.7 KXZ45559.1 - 0.0003 20.7 6.5 0.13 12.1 0.5 2.2 2 0 0 2 2 2 2 SpoIIIAH-like protein TRP PF06011.12 KXZ45559.1 - 0.0013 17.5 1.8 0.0031 16.3 1.8 1.7 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Zip PF02535.22 KXZ45559.1 - 0.0029 16.9 0.1 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 ZIP Zinc transporter SAPS PF04499.15 KXZ45559.1 - 0.028 13.2 0.2 0.049 12.4 0.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Laminin_EGF PF00053.24 KXZ45559.1 - 0.057 13.6 1.5 0.12 12.6 1.5 1.5 1 0 0 1 1 1 0 Laminin EGF domain V_ATPase_I PF01496.19 KXZ45559.1 - 0.11 10.4 1.9 0.16 9.9 0.5 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 KXZ45559.1 - 0.15 11.8 3.9 0.71 9.5 2.2 2.3 2 0 0 2 2 2 0 FAM176 family Connexin PF00029.19 KXZ45559.1 - 0.15 11.8 2.2 1.1 9.0 0.6 2.3 2 0 0 2 2 2 0 Connexin CCDC53 PF10152.9 KXZ45559.1 - 1.4 9.3 9.6 0.4 11.1 3.9 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CDC45 PF02724.14 KXZ45559.1 - 1.7 6.9 11.4 1.2 7.3 9.5 1.6 2 0 0 2 2 2 0 CDC45-like protein NPR3 PF03666.13 KXZ45559.1 - 7.3 5.3 7.0 3.1 6.5 1.4 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3464 PF11947.8 KXZ45559.1 - 8.2 6.2 9.4 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Chlam_PMP PF02415.17 KXZ45560.1 - 0.082 13.4 59.5 0.57 10.8 0.5 9.6 9 2 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat MG4 PF17789.1 KXZ45560.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Macroglobulin domain MG4 Ank_2 PF12796.7 KXZ45562.1 - 7.3e-17 61.7 6.3 4.4e-05 24.0 1.0 4.9 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45562.1 - 1.4e-08 35.1 13.0 0.0017 18.9 0.2 6.9 4 2 4 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45562.1 - 3e-08 33.3 9.7 0.55 11.0 0.0 8.7 9 1 1 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 KXZ45562.1 - 0.00011 22.4 6.7 1.8 9.0 0.3 5.4 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ45562.1 - 0.051 14.1 11.7 1e+02 3.6 0.1 6.4 3 2 1 4 4 4 0 Ankyrin repeat CutC PF03932.14 KXZ45563.1 - 7.2e-30 104.0 0.1 1.3e-29 103.2 0.1 1.3 1 0 0 1 1 1 1 CutC family Beach PF02138.18 KXZ45563.1 - 3.9e-18 65.8 0.0 6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain FAD_binding_3 PF01494.19 KXZ45563.1 - 6.6e-11 42.0 9.7 7.9e-06 25.3 0.2 3.4 3 0 0 3 3 3 3 FAD binding domain Thi4 PF01946.17 KXZ45563.1 - 0.00024 20.4 0.1 0.00084 18.6 0.1 1.9 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXZ45563.1 - 0.02 14.0 0.8 0.037 13.1 0.8 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXZ45563.1 - 0.024 14.7 0.1 0.06 13.3 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding WD40 PF00400.32 KXZ45563.1 - 0.064 14.1 0.0 0.26 12.2 0.0 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat Mur_ligase_M PF08245.12 KXZ45564.1 - 2.4e-08 34.2 0.0 5.7e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KXZ45564.1 - 0.15 12.3 0.0 0.48 10.7 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DinB_2 PF12867.7 KXZ45564.1 - 0.51 10.8 2.8 38 4.8 0.7 3.2 2 1 1 3 3 3 0 DinB superfamily Methyltransf_12 PF08242.12 KXZ45565.1 - 3.9e-07 30.7 0.0 6.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ45565.1 - 4.5e-06 27.3 0.0 6.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ45565.1 - 0.00043 19.9 0.0 0.00056 19.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KXZ45565.1 - 0.00076 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ45565.1 - 0.0048 16.7 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ45565.1 - 0.0079 16.8 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ45566.1 - 4.4e-06 26.6 0.0 1.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ45566.1 - 0.015 15.9 0.1 0.74 10.6 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ45566.1 - 0.017 15.8 0.0 0.095 13.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain LpoB PF13036.6 KXZ45567.1 - 0.0056 16.6 0.2 0.061 13.3 0.1 2.1 2 0 0 2 2 2 1 Peptidoglycan-synthase activator LpoB Borrelia_P13 PF05628.12 KXZ45567.1 - 0.045 13.7 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Borrelia membrane protein P13 Ank_2 PF12796.7 KXZ45568.1 - 5.8e-23 81.3 3.1 1.2e-14 54.6 0.2 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45568.1 - 3.1e-17 62.7 0.1 1.6e-12 47.7 0.2 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ45568.1 - 1.3e-16 60.2 0.2 2.8e-05 24.4 0.0 3.4 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KXZ45568.1 - 3.2e-16 57.8 0.0 9.6e-06 25.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ45568.1 - 3.9e-16 58.9 0.9 2.5e-08 34.0 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ant_C PF05586.11 KXZ45568.1 - 0.09 13.4 0.1 0.82 10.3 0.0 2.5 2 1 0 3 3 3 0 Anthrax receptor C-terminus region RRM_1 PF00076.22 KXZ45570.1 - 6.4e-38 128.4 0.0 2.8e-14 52.7 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXZ45570.1 - 5.2e-18 65.9 2.3 2.2e-17 63.9 0.0 2.5 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 KXZ45570.1 - 0.0011 19.0 0.0 4.4 7.4 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXZ45570.1 - 0.14 12.2 0.1 7.3 6.7 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif S6PP PF05116.13 KXZ45571.1 - 2.2e-49 168.2 0.0 3e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 KXZ45571.1 - 2.8e-13 50.2 0.0 4.8e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ45571.1 - 4.9e-05 23.8 0.2 0.0069 16.8 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P_proprotein PF01483.20 KXZ45572.1 - 0.015 15.3 0.1 0.88 9.6 0.1 2.6 2 0 0 2 2 2 0 Proprotein convertase P-domain AATF-Che1 PF13339.6 KXZ45572.1 - 0.084 13.6 3.3 0.84 10.3 2.5 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Syntaxin PF00804.25 KXZ45572.1 - 0.43 10.2 3.9 0.18 11.4 0.4 1.9 2 0 0 2 2 2 0 Syntaxin Apolipoprotein PF01442.18 KXZ45572.1 - 0.83 9.5 11.7 4e+02 0.7 11.2 2.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FAA_hydrolase_N PF09298.11 KXZ45572.1 - 3.4 7.9 9.4 3.7 7.8 1.2 3.4 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal IGPD PF00475.18 KXZ45573.1 - 1.4e-64 216.7 1.5 2.4e-64 216.0 0.7 1.7 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase UQ_con PF00179.26 KXZ45574.1 - 8.1e-36 122.7 0.0 9.6e-36 122.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXZ45574.1 - 0.0044 16.7 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 KXZ45574.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 KXZ45574.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 KXZ45575.1 - 8.9e-05 22.0 0.0 0.00031 20.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45575.1 - 0.077 12.3 0.0 4.6 6.5 0.0 2.9 2 1 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 KXZ45576.1 - 0.00011 21.7 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PAP2 PF01569.21 KXZ45577.1 - 1.2e-19 70.4 1.2 2e-19 69.7 0.7 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KXZ45577.1 - 0.12 12.9 0.4 0.12 12.9 0.4 1.9 2 1 0 2 2 2 0 PAP2 superfamily C-terminal UPF0060 PF02694.15 KXZ45578.1 - 5.3e-33 113.4 10.9 6.2e-33 113.2 10.9 1.1 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family DUF1772 PF08592.11 KXZ45578.1 - 0.35 11.2 4.9 6.6 7.1 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) UCH PF00443.29 KXZ45579.1 - 2.8e-56 190.9 0.1 3.3e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ45579.1 - 2.8e-29 102.7 0.4 8.9e-29 101.1 0.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KXZ45579.1 - 0.0021 17.6 9.9 0.21 11.1 9.1 2.8 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase FBD PF08387.10 KXZ45579.1 - 0.0071 16.2 0.2 0.42 10.5 0.0 3.1 3 0 0 3 3 3 1 FBD ELFV_dehydrog PF00208.21 KXZ45580.1 - 2.3e-53 181.4 0.1 1.7e-51 175.3 0.1 2.2 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KXZ45580.1 - 2.4e-43 147.1 0.1 5e-43 146.1 0.1 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KXZ45580.1 - 0.085 12.2 0.2 0.2 11.0 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 KXZ45580.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 KXZ45580.1 - 0.15 12.5 0.1 0.38 11.2 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Glyco_transf_90 PF05686.12 KXZ45583.1 - 0.0022 17.0 0.1 0.0053 15.7 0.0 1.6 2 1 0 2 2 2 1 Glycosyl transferase family 90 SNARE_assoc PF09335.11 KXZ45584.1 - 1.4e-18 67.5 9.1 1.4e-18 67.5 9.1 2.1 1 1 1 2 2 2 1 SNARE associated Golgi protein DUF4491 PF14898.6 KXZ45584.1 - 0.17 12.4 0.3 0.17 12.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Pkinase PF00069.25 KXZ45585.1 - 8.2e-55 186.0 0.0 1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45585.1 - 1.3e-30 106.6 0.0 1.7e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ45585.1 - 7.3e-08 31.6 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ45585.1 - 8.5e-07 28.6 0.0 1.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KXZ45585.1 - 0.035 13.7 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXZ45585.1 - 0.046 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ45585.1 - 0.064 12.6 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.23 KXZ45586.1 - 1e-63 215.3 0.0 1.4e-44 152.4 0.0 2.1 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KXZ45586.1 - 5.7e-10 39.3 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 KXZ45586.1 - 0.0068 16.2 0.1 0.025 14.4 0.1 2.0 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat DUF2087 PF09860.9 KXZ45586.1 - 0.11 12.7 0.6 0.91 9.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Csm1_N PF18504.1 KXZ45586.1 - 0.16 12.3 2.6 6.3 7.2 0.1 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain ATG16 PF08614.11 KXZ45586.1 - 0.41 10.8 9.8 0.42 10.8 3.5 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SIKE PF05769.11 KXZ45586.1 - 0.47 10.4 6.1 0.69 9.8 2.1 2.4 2 0 0 2 2 2 0 SIKE family Rootletin PF15035.6 KXZ45586.1 - 0.6 10.1 6.6 1.1 9.3 3.5 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.11 KXZ45586.1 - 1.1 8.0 6.1 0.68 8.8 1.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KXZ45586.1 - 1.3 9.6 7.1 0.48 11.0 0.7 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region MscS_porin PF12795.7 KXZ45586.1 - 1.8 8.0 18.4 4.7 6.7 1.9 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain SRCR PF00530.18 KXZ45588.1 - 2.6e-07 31.0 0.1 9.4e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain TRP PF06011.12 KXZ45588.1 - 2.7e-05 23.1 7.2 5.4e-05 22.1 7.2 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel CwfJ_C_2 PF04676.14 KXZ45589.1 - 7.2e-32 110.2 0.0 1.6e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KXZ45589.1 - 2.2e-15 56.6 0.0 4.1e-14 52.5 0.0 2.2 1 1 1 2 2 2 1 Protein similar to CwfJ C-terminus 1 CCDC53 PF10152.9 KXZ45590.1 - 3.9 7.9 7.6 30 5.0 7.6 2.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Rab5-bind PF09311.11 KXZ45591.1 - 3.5e-06 26.6 24.0 3.5e-06 26.6 24.0 7.9 2 2 4 8 8 8 3 Rabaptin-like protein IL15 PF02372.15 KXZ45591.1 - 0.22 11.5 2.6 2 8.5 0.3 3.1 2 1 0 2 2 2 0 Interleukin 15 BBS1 PF14779.6 KXZ45593.1 - 3.1e-67 226.7 0.0 2.4e-66 223.8 0.0 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 KXZ45593.1 - 0.0015 18.6 0.0 0.011 15.7 0.0 2.4 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region CHRD PF07452.12 KXZ45593.1 - 0.02 15.9 0.0 5.3 8.1 0.0 2.6 2 1 0 2 2 2 0 CHRD domain PHTB1_N PF14727.6 KXZ45593.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 PTHB1 N-terminus RRM_1 PF00076.22 KXZ45594.1 - 7e-07 29.0 0.0 0.0056 16.5 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.17 KXZ45595.1 - 4.1e-16 59.1 0.0 3.1e-15 56.1 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ45595.1 - 4.7e-15 55.7 0.0 6.2e-14 52.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KXZ45596.1 - 8.9e-09 35.8 5.2 0.003 18.1 0.4 4.0 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45596.1 - 6e-06 26.7 10.6 2.6 8.7 0.1 6.7 4 3 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45596.1 - 0.0028 18.0 9.2 95 4.1 0.0 8.2 9 0 0 9 9 9 0 Ankyrin repeat HTH_15 PF12324.8 KXZ45596.1 - 0.049 13.6 0.5 2.2 8.3 0.4 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase FR47 PF08445.10 KXZ45597.1 - 2.7e-07 30.5 0.2 2.6e-05 24.1 0.2 2.6 1 1 0 1 1 1 1 FR47-like protein Pkinase_Tyr PF07714.17 KXZ45598.1 - 9.9e-37 126.6 0.0 9.1e-29 100.5 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ45598.1 - 2.2e-28 99.3 0.0 2.3e-21 76.3 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain PAS_9 PF13426.7 KXZ45598.1 - 0.008 16.4 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain BSP_II PF05432.11 KXZ45598.1 - 0.019 14.7 3.9 0.048 13.4 3.9 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 KXZ45598.1 - 3.3 8.1 6.1 7 7.1 6.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Radial_spoke PF04712.12 KXZ45598.1 - 9.7 5.0 8.5 15 4.3 8.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Cupin_2 PF07883.11 KXZ45599.1 - 4.3e-05 23.2 0.1 0.00017 21.3 0.0 1.9 1 1 1 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KXZ45599.1 - 0.018 14.7 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Cupin SWI-SNF_Ssr4 PF08549.10 KXZ45599.1 - 0.031 12.9 0.1 0.035 12.8 0.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GST_C_3 PF14497.6 KXZ45600.1 - 1.1e-15 57.6 0.0 1.8e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXZ45600.1 - 1.1e-07 32.1 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ45600.1 - 2.4e-07 30.9 0.0 4.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXZ45600.1 - 0.0065 16.9 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXZ45601.1 - 2.8e-15 56.3 0.0 4.3e-15 55.7 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXZ45601.1 - 2e-06 27.9 0.0 6.6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ45601.1 - 0.089 12.8 1.8 0.49 10.5 1.8 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KXZ45603.1 - 0.00097 19.0 0.3 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KXZ45603.1 - 0.00097 19.5 5.0 0.18 12.3 0.0 5.3 7 0 0 7 7 7 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ45603.1 - 0.0017 18.1 0.6 14 5.5 0.1 4.8 5 0 0 5 5 5 1 Leucine rich repeat EAL PF00563.20 KXZ45603.1 - 0.016 14.7 0.6 0.22 11.0 0.1 2.3 2 0 0 2 2 2 0 EAL domain Semialdhyde_dhC PF02774.18 KXZ45603.1 - 0.1 12.6 0.5 0.19 11.8 0.5 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DUF2063 PF09836.9 KXZ45603.1 - 0.18 12.0 0.8 1.5 9.1 0.2 2.4 2 0 0 2 2 2 0 Putative DNA-binding domain Trns_repr_metal PF02583.17 KXZ45603.1 - 0.46 10.9 5.1 0.14 12.5 0.8 2.4 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor GST_C_3 PF14497.6 KXZ45605.1 - 6.1e-16 58.4 0.0 1.1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXZ45605.1 - 8.8e-09 35.6 0.0 2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ45605.1 - 7.2e-07 29.4 0.0 1.6e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXZ45605.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ45605.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 KXZ45606.1 - 4.9e-54 183.5 0.0 1.6e-23 83.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45606.1 - 2.8e-21 76.0 0.0 3.8e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ45606.1 - 0.018 15.0 0.5 0.018 15.0 0.5 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ45606.1 - 0.037 13.4 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DRMBL PF07522.14 KXZ45608.1 - 4.7e-23 81.5 0.0 2.2e-22 79.3 0.0 1.9 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase F-box PF00646.33 KXZ45609.1 - 0.014 15.2 0.2 0.049 13.5 0.2 1.9 1 0 0 1 1 1 0 F-box domain RPT PF13446.6 KXZ45610.1 - 0.076 12.9 0.0 3.3 7.7 0.0 2.9 3 0 0 3 3 3 0 A repeated domain in UCH-protein TPR_16 PF13432.6 KXZ45610.1 - 3.9 8.2 9.1 0.31 11.7 2.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Band_7_C PF16200.5 KXZ45612.1 - 0.0025 17.8 0.0 0.011 15.7 0.0 2.1 1 0 0 1 1 1 1 C-terminal region of band_7 WHIM1 PF15612.6 KXZ45613.1 - 0.008 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 F_actin_bund_C PF18060.1 KXZ45614.1 - 1.8 8.7 14.4 3.4 7.8 1.5 3.1 2 0 0 2 2 2 0 F actin bundling C terminal Kelch_4 PF13418.6 KXZ45615.1 - 2e-14 53.3 0.0 2.3e-06 27.5 0.0 4.0 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXZ45615.1 - 3.1e-14 52.8 2.8 5.6e-08 32.9 0.1 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ45615.1 - 7.1e-10 38.8 0.3 0.013 15.8 0.0 3.5 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KXZ45615.1 - 2.6e-09 36.9 0.1 0.021 14.8 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 KXZ45615.1 - 4e-09 35.9 2.5 0.00011 21.7 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KXZ45615.1 - 4.8e-06 26.3 0.0 0.16 12.0 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KXZ45616.1 - 1.3e-17 63.6 14.7 1.9e-09 37.6 0.0 6.8 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KXZ45616.1 - 1.4e-15 57.0 1.9 1.5e-05 24.9 0.0 5.6 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ45616.1 - 3.5e-14 52.5 7.8 1.3e-06 28.5 0.0 4.3 3 2 2 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KXZ45616.1 - 8.7e-12 44.8 0.0 0.03 14.3 0.0 5.2 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KXZ45616.1 - 5.6e-11 41.9 0.0 0.036 13.6 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 KXZ45616.1 - 2.8e-07 30.2 0.0 0.0036 17.2 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Jun PF03957.13 KXZ45616.1 - 0.46 10.3 8.5 3.2 7.6 0.5 2.3 2 0 0 2 2 2 0 Jun-like transcription factor zf-MYND PF01753.18 KXZ45617.1 - 7.6e-06 25.9 8.2 7.6e-06 25.9 8.2 1.9 2 0 0 2 2 2 1 MYND finger DUF4658 PF15555.6 KXZ45619.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) WD40 PF00400.32 KXZ45621.1 - 1.3e-26 92.2 11.4 0.00091 20.0 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ45621.1 - 6e-18 64.9 4.8 2.6e-09 37.3 0.2 4.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ45621.1 - 2.6e-07 30.7 0.0 0.14 12.0 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXZ45621.1 - 0.00013 21.1 1.0 0.63 8.9 0.6 3.9 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXZ45621.1 - 0.22 9.5 0.0 1.2 7.0 0.0 1.9 2 0 0 2 2 2 0 IKI3 family Copine PF07002.16 KXZ45622.1 - 2.6e-62 210.2 0.0 3.4e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Copine U-box PF04564.15 KXZ45622.1 - 1.2e-17 63.8 0.0 2.5e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain vWA-TerF-like PF10138.9 KXZ45622.1 - 5.1e-06 26.7 0.0 2.5e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 vWA found in TerF C terminus zf-Nse PF11789.8 KXZ45622.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KXZ45622.1 - 0.033 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF5011 PF16403.5 KXZ45624.1 - 7.6e-09 35.6 0.8 4.2e-05 23.6 0.2 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF5011) PKD_channel PF08016.12 KXZ45625.1 - 5.6e-12 45.1 9.6 2.1e-09 36.6 9.0 2.2 2 0 0 2 2 2 2 Polycystin cation channel DUF5011 PF16403.5 KXZ45625.1 - 0.0019 18.3 4.0 7.4 6.8 0.1 4.9 4 0 0 4 4 4 2 Domain of unknown function (DUF5011) GP67 PF17634.2 KXZ45625.1 - 0.0098 16.3 7.7 0.023 15.1 7.7 1.5 1 0 0 1 1 1 1 Gene product 67 LamB_YcsF PF03746.16 KXZ45625.1 - 0.018 14.7 0.1 0.05 13.3 0.1 1.7 1 0 0 1 1 1 0 LamB/YcsF family Ion_trans PF00520.31 KXZ45625.1 - 1.8 7.7 16.5 0.49 9.6 12.7 1.8 2 0 0 2 2 2 0 Ion transport protein Myc_N PF01056.18 KXZ45625.1 - 4.4 7.1 7.1 11 5.9 7.1 1.6 1 0 0 1 1 1 0 Myc amino-terminal region DUF2052 PF09747.9 KXZ45625.1 - 9.7 6.3 11.3 0.53 10.4 5.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Peptidase_M14 PF00246.24 KXZ45627.1 - 3.2e-13 50.2 0.0 6.6e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KXZ45627.1 - 0.0083 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Sporozoite_P67 PF05642.11 KXZ45627.1 - 1.6 6.7 19.6 0.0071 14.5 8.1 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen GPDPase_memb PF10110.9 KXZ45629.1 - 0.056 12.2 0.7 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Ank_2 PF12796.7 KXZ45630.1 - 3e-10 40.5 0.2 0.00011 22.7 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ45630.1 - 4.1e-07 29.8 2.9 0.51 11.1 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXZ45630.1 - 2e-05 25.0 1.4 0.036 14.6 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ45630.1 - 0.0029 18.0 7.4 2.3 8.8 0.8 4.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXZ45630.1 - 0.018 15.4 3.0 4.2 7.8 0.1 3.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KXZ45631.1 - 7.4e-30 104.1 0.0 1.8e-25 89.7 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ45631.1 - 1.8e-26 93.1 0.0 5.2e-23 81.7 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ45631.1 - 0.027 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF5011 PF16403.5 KXZ45634.1 - 4.7e-15 55.5 8.5 3.7e-06 27.0 0.0 5.5 5 0 0 5 5 5 3 Domain of unknown function (DUF5011) PKD_channel PF08016.12 KXZ45634.1 - 4.4e-11 42.1 9.8 8.2e-11 41.2 9.8 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KXZ45634.1 - 1.4 8.1 12.2 1.2 8.2 10.9 1.5 2 0 0 2 2 2 0 Ion transport protein PAN_4 PF14295.6 KXZ45635.1 - 5.9e-21 74.1 35.9 1e-05 25.4 0.4 7.7 7 0 0 7 7 7 7 PAN domain PAN_1 PF00024.26 KXZ45635.1 - 2.7e-19 68.9 12.4 0.00035 20.5 0.1 7.0 7 0 0 7 7 7 6 PAN domain PAN_2 PF08276.11 KXZ45635.1 - 2.4e-07 30.7 44.1 0.0069 16.5 0.6 8.2 8 0 0 8 8 8 5 PAN-like domain PAN_3 PF08277.12 KXZ45635.1 - 0.2 11.5 30.4 0.55 10.1 0.2 7.4 8 0 0 8 8 8 0 PAN-like domain PAN_1 PF00024.26 KXZ45636.1 - 8.4e-24 83.3 36.8 2.1e-05 24.4 1.5 8.9 9 0 0 9 9 9 7 PAN domain PAN_4 PF14295.6 KXZ45636.1 - 9.4e-11 41.4 60.7 0.001 18.9 2.2 9.4 9 0 0 9 9 9 6 PAN domain PAN_2 PF08276.11 KXZ45636.1 - 1.8e-08 34.4 45.4 0.0014 18.7 1.0 8.3 8 0 0 8 8 8 6 PAN-like domain PAN_3 PF08277.12 KXZ45636.1 - 0.39 10.6 35.1 0.55 10.1 0.6 7.0 7 0 0 7 7 7 0 PAN-like domain PAN_1 PF00024.26 KXZ45637.1 - 0.00014 21.7 1.1 0.011 15.6 0.5 2.5 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 KXZ45637.1 - 0.021 14.7 8.4 0.15 12.0 3.0 2.8 2 0 0 2 2 2 0 PAN domain Pkinase PF00069.25 KXZ45638.1 - 0.0071 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45638.1 - 0.098 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase zf-MYND PF01753.18 KXZ45639.1 - 3.9e-07 30.0 9.3 1.3e-06 28.4 9.3 1.9 1 0 0 1 1 1 1 MYND finger Pkinase_Tyr PF07714.17 KXZ45640.1 - 8.5e-09 35.1 0.0 2.2e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ45640.1 - 4.3e-08 32.8 0.0 2.8e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Ufd2P_core PF10408.9 KXZ45643.1 - 1.2e-139 466.9 0.0 1.3e-139 466.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KXZ45643.1 - 6.9e-29 99.8 0.4 1.4e-28 98.8 0.4 1.6 1 0 0 1 1 1 1 U-box domain Toluene_X PF03349.16 KXZ45643.1 - 2.8 6.4 4.0 4.9 5.6 4.0 1.3 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) CMAS PF02353.20 KXZ45644.1 - 1.7e-40 139.0 0.0 2.3e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXZ45644.1 - 1.5e-13 50.9 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ45644.1 - 3.6e-13 50.0 0.0 5.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ45644.1 - 1.4e-11 44.9 0.0 2.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ45644.1 - 1.2e-10 42.1 0.0 1.8e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ45644.1 - 6.8e-10 38.9 0.0 9.6e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ45644.1 - 6.2e-06 25.9 0.0 9.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KXZ45644.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.12 KXZ45644.1 - 0.00037 20.3 0.0 0.00065 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KXZ45644.1 - 0.00059 19.4 0.0 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase DUF2194 PF09960.9 KXZ45644.1 - 0.0095 14.3 0.0 0.015 13.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Cons_hypoth95 PF03602.15 KXZ45644.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 KXZ45644.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FtsJ PF01728.19 KXZ45644.1 - 0.055 13.6 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KXZ45644.1 - 0.07 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXZ45644.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase_Tyr PF07714.17 KXZ45645.1 - 5.5e-36 124.2 0.0 6.6e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ45645.1 - 4.6e-29 101.6 0.0 9.5e-29 100.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ45645.1 - 1.9e-05 23.6 0.0 2.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ45645.1 - 0.008 16.1 0.2 0.02 14.9 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ45645.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Baculo_LEF-3 PF05847.11 KXZ45645.1 - 0.093 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) PKD_channel PF08016.12 KXZ45646.1 - 2.7e-11 42.8 5.6 2.9e-09 36.1 2.9 2.1 2 0 0 2 2 2 2 Polycystin cation channel DUF5011 PF16403.5 KXZ45646.1 - 1.7e-08 34.4 12.0 2.1 8.5 0.1 7.5 6 1 1 7 7 7 6 Domain of unknown function (DUF5011) FOP_dimer PF09398.10 KXZ45647.1 - 6e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KXZ45647.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 LisH DUF3275 PF11679.8 KXZ45647.1 - 0.28 11.1 1.9 1.7 8.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) CactinC_cactus PF09732.9 KXZ45648.1 - 1.6e-58 196.1 8.3 2.6e-58 195.4 8.3 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KXZ45648.1 - 6.7e-37 127.2 0.0 6.7e-37 127.2 0.0 2.5 2 0 0 2 2 2 1 Conserved mid region of cactin SF3A2 PF16835.5 KXZ45648.1 - 0.034 14.5 0.1 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) FAST_1 PF06743.15 KXZ45649.1 - 2.9e-06 27.1 0.0 8.8 6.4 0.0 5.7 6 0 0 6 6 6 3 FAST kinase-like protein, subdomain 1 zf-MYND PF01753.18 KXZ45650.1 - 4.2e-06 26.7 8.9 1.4e-05 25.1 8.9 1.9 1 0 0 1 1 1 1 MYND finger Sgf11 PF08209.11 KXZ45650.1 - 0.47 10.1 4.2 0.23 11.1 0.9 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Lipase_GDSL_2 PF13472.6 KXZ45651.1 - 2.2e-17 64.0 0.1 3.4e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXZ45651.1 - 3.5e-11 43.4 0.0 4.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pkinase_Tyr PF07714.17 KXZ45652.1 - 4.7e-30 104.7 0.0 2.8e-16 59.6 0.0 3.4 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ45652.1 - 6.6e-29 101.1 0.0 1.3e-16 60.7 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain SKG6 PF08693.10 KXZ45652.1 - 0.047 13.1 3.6 0.14 11.6 3.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EMC3_TMCO1 PF01956.16 KXZ45653.1 - 2.3e-37 128.3 0.7 2.3e-37 128.3 0.7 2.2 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like ABC2_membrane_2 PF12679.7 KXZ45653.1 - 0.041 13.2 0.1 0.1 11.8 0.1 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3155 PF11352.8 KXZ45653.1 - 0.14 12.6 0.1 22 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) zf-AN1 PF01428.16 KXZ45654.1 - 0.71 10.1 11.4 1.8 8.8 5.9 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger IBR PF01485.21 KXZ45654.1 - 0.76 10.0 11.1 0.15 12.3 5.7 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-HIT PF04438.16 KXZ45654.1 - 7.6 6.5 13.8 8.1 6.4 8.8 2.3 2 0 0 2 2 2 0 HIT zinc finger CAP_N PF01213.19 KXZ45655.1 - 6.6 6.1 5.0 9.3 5.6 5.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SnoaL PF07366.12 KXZ45656.1 - 0.007 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase WD40 PF00400.32 KXZ45657.1 - 5e-07 30.3 1.6 1.2 10.1 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ45657.1 - 0.00013 22.2 0.0 1.6 9.1 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2306 PF10067.9 KXZ45658.1 - 0.00028 21.1 0.5 0.00035 20.8 0.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) SprT-like PF10263.9 KXZ45659.1 - 0.029 14.2 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 SprT-like family ChitinaseA_N PF08329.10 KXZ45659.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Glyco_transf_10 PF00852.19 KXZ45659.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF1825 PF08855.10 KXZ45660.1 - 1.7e-19 69.7 0.4 3.1e-19 68.8 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1825) STI1 PF17830.1 KXZ45660.1 - 0.033 14.1 0.1 0.26 11.2 0.0 2.6 3 1 0 3 3 3 0 STI1 domain DUF5587 PF17825.1 KXZ45660.1 - 0.1 9.8 0.2 0.13 9.5 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5587) PAS PF00989.25 KXZ45662.1 - 4.1e-07 30.0 0.0 0.15 12.1 0.0 4.4 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 KXZ45662.1 - 2.6e-06 27.6 0.0 0.08 13.2 0.0 4.4 5 0 0 5 5 5 2 PAS domain PAS_8 PF13188.7 KXZ45662.1 - 0.0078 16.2 0.0 0.14 12.2 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KXZ45662.1 - 0.1 12.9 0.0 5.5 7.3 0.0 3.5 3 0 0 3 3 3 0 PAS fold Ribosomal_L30_N PF08079.12 KXZ45662.1 - 0.24 11.7 0.3 0.55 10.5 0.3 1.5 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Acetyltransf_10 PF13673.7 KXZ45663.1 - 4.8e-14 52.4 0.0 1e-13 51.3 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ45663.1 - 7.2e-14 52.0 0.0 1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ45663.1 - 4.1e-12 46.4 0.0 4.6e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXZ45663.1 - 2.9e-06 27.4 0.0 4e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ45663.1 - 8.6e-06 25.6 0.0 5.8e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_6 PF13480.7 KXZ45663.1 - 0.045 13.9 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Las1 PF04031.13 KXZ45664.1 - 1.1e-24 87.3 0.0 2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Las1-like AAA PF00004.29 KXZ45664.1 - 1.9e-06 28.3 0.0 3.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ45664.1 - 0.00025 21.5 0.6 0.00025 21.5 0.6 2.2 2 2 0 2 2 1 1 AAA ATPase domain AAA_28 PF13521.6 KXZ45664.1 - 0.0013 19.0 0.3 0.005 17.1 0.2 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KXZ45664.1 - 0.0035 17.9 0.0 0.0077 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXZ45664.1 - 0.0049 16.9 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXZ45664.1 - 0.0056 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KXZ45664.1 - 0.0078 16.3 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KXZ45664.1 - 0.013 15.2 0.2 0.05 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXZ45664.1 - 0.019 15.3 0.0 0.061 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXZ45664.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ45664.1 - 0.025 15.1 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KXZ45664.1 - 0.033 13.8 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXZ45664.1 - 0.038 14.2 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXZ45664.1 - 0.042 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_11 PF13086.6 KXZ45664.1 - 0.054 13.3 1.0 0.061 13.1 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 KXZ45664.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KXZ45664.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.17 KXZ45664.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KXZ45664.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KXZ45664.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 KXZ45664.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 KXZ45664.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KXZ45664.1 - 0.15 11.9 0.0 0.46 10.4 0.0 1.5 1 1 1 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 KXZ45664.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PAS_9 PF13426.7 KXZ45666.1 - 5.6e-05 23.3 0.0 0.036 14.3 0.0 4.2 5 0 0 5 5 5 1 PAS domain PAS_4 PF08448.10 KXZ45666.1 - 0.0022 18.2 0.0 0.025 14.9 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 KXZ45666.1 - 0.0034 17.4 1.0 0.22 11.6 0.0 4.1 5 0 0 5 5 5 1 PAS fold Med3 PF11593.8 KXZ45666.1 - 5.6 6.1 6.1 7 5.7 0.7 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal TMEM132D_C PF15706.5 KXZ45667.1 - 0.057 13.2 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PAS_9 PF13426.7 KXZ45668.1 - 1.9e-05 24.8 0.0 0.017 15.3 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KXZ45668.1 - 3e-05 24.2 0.1 0.0073 16.5 0.0 3.8 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 KXZ45668.1 - 0.003 17.6 0.0 2.8 8.0 0.0 3.9 4 0 0 4 4 4 1 PAS fold Baculo_11_kDa PF06143.11 KXZ45668.1 - 1.8 8.2 5.3 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family PAS_4 PF08448.10 KXZ45669.1 - 4.6e-05 23.6 0.0 0.021 15.1 0.0 3.7 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KXZ45669.1 - 7.1e-05 23.0 0.0 0.0085 16.3 0.0 3.5 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 KXZ45669.1 - 0.034 14.1 0.0 2.7 8.0 0.0 3.7 5 0 0 5 5 5 0 PAS fold Pro_isomerase PF00160.21 KXZ45670.1 - 1.1e-48 165.5 0.2 1.2e-48 165.3 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ThiF PF00899.21 KXZ45671.1 - 0.0014 18.0 0.0 0.0059 16.0 0.0 1.8 1 1 0 1 1 1 1 ThiF family C2 PF00168.30 KXZ45673.1 - 5.3e-30 103.8 0.0 8.3e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain Lipase_3 PF01764.25 KXZ45673.1 - 3.9e-29 101.3 0.0 1.3e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXZ45673.1 - 0.0073 16.9 0.4 0.0073 16.9 0.4 3.0 3 1 0 3 3 3 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KXZ45673.1 - 0.058 12.9 0.0 2.5 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KXZ45673.1 - 0.068 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4780 PF16012.5 KXZ45673.1 - 0.23 10.9 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) C2 PF00168.30 KXZ45674.1 - 3.7e-33 113.9 0.0 3.3e-15 56.2 0.0 2.7 2 0 0 2 2 2 2 C2 domain Lipase_3 PF01764.25 KXZ45674.1 - 4.5e-28 97.9 0.0 7.4e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXZ45674.1 - 0.0022 18.6 1.1 0.0022 18.6 1.1 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ45674.1 - 0.0072 15.6 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KXZ45674.1 - 0.025 14.1 0.1 0.18 11.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Esterase PF00756.20 KXZ45674.1 - 0.082 12.5 0.1 0.9 9.1 0.1 2.5 3 0 0 3 3 3 0 Putative esterase PGAP1 PF07819.13 KXZ45674.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein C2 PF00168.30 KXZ45675.1 - 2.6e-31 107.9 0.0 4e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain Lipase_3 PF01764.25 KXZ45675.1 - 2.8e-30 105.0 0.0 4.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXZ45675.1 - 0.0075 16.9 0.4 0.027 15.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KXZ45675.1 - 0.02 14.4 0.0 0.17 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KXZ45677.1 - 2e-32 112.0 0.0 6.4e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) C2 PF00168.30 KXZ45677.1 - 1.6e-15 57.2 0.0 2.7e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF2974 PF11187.8 KXZ45677.1 - 0.00033 20.3 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) PGAP1 PF07819.13 KXZ45677.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Glyco_hydro_7 PF00840.20 KXZ45678.1 - 0.17 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Rox3 PF08633.10 KXZ45679.1 - 0.017 15.4 0.2 0.024 14.9 0.2 1.3 1 0 0 1 1 1 0 Rox3 mediator complex subunit Glyco_hydro_7 PF00840.20 KXZ45679.1 - 0.052 12.3 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 DnaJ PF00226.31 KXZ45680.1 - 2.4e-05 24.4 0.0 8.5e-05 22.6 0.0 1.9 3 0 0 3 3 3 1 DnaJ domain Pam16 PF03656.13 KXZ45680.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Pam16 DUF1517 PF07466.11 KXZ45681.1 - 1.5e-38 132.8 0.0 1.9e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) Histone PF00125.24 KXZ45682.1 - 2.9e-39 134.4 0.9 2.9e-39 134.4 0.9 1.9 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXZ45682.1 - 1.3e-05 25.2 1.9 2.6e-05 24.3 0.1 2.3 2 1 1 3 3 3 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ45682.1 - 0.0019 18.4 0.3 0.0054 17.0 0.3 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXZ45682.1 - 0.0047 17.3 0.0 0.0071 16.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein DUF3729 PF12526.8 KXZ45682.1 - 1.4 10.5 5.3 2.3 9.8 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) DnaJ PF00226.31 KXZ45683.1 - 9.8e-13 48.0 0.0 1.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Alg6_Alg8 PF03155.15 KXZ45684.1 - 3e-135 451.9 0.0 2.3e-134 449.0 0.0 1.9 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Vps26 PF03643.15 KXZ45685.1 - 2.5e-104 348.1 0.0 3.2e-104 347.8 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Myb_DNA-binding PF00249.31 KXZ45686.1 - 1.3e-19 70.1 3.5 1.4e-11 44.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ45686.1 - 2e-14 53.5 1.1 4.9e-07 29.9 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 KXZ45686.1 - 0.22 11.2 0.0 0.49 10.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 BTB PF00651.31 KXZ45687.1 - 3.9e-11 43.2 0.0 6.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KXZ45687.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Histone PF00125.24 KXZ45688.1 - 2.8e-39 134.5 2.5 2.8e-39 134.5 2.5 2.1 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXZ45688.1 - 1.3e-06 28.5 0.1 1.3e-06 28.5 0.1 1.9 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ45688.1 - 0.0047 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXZ45688.1 - 0.0085 16.4 0.5 0.0085 16.4 0.5 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ45688.1 - 0.11 12.6 0.4 0.22 11.6 0.1 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PAM2 PF07145.15 KXZ45689.1 - 4.9e-05 22.7 23.5 1.3 8.8 0.2 6.8 6 0 0 6 6 6 4 Ataxin-2 C-terminal region zf-C3HC4_3 PF13920.6 KXZ45689.1 - 0.0041 17.0 8.1 0.0066 16.3 8.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_C2H2_13 PF18508.1 KXZ45689.1 - 0.11 12.1 0.1 0.29 10.7 0.1 1.6 2 0 0 2 2 2 0 Zinc finger domain BTB PF00651.31 KXZ45690.1 - 2.8e-10 40.4 0.0 4.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ45691.1 - 2.2e-12 47.2 0.0 3.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_31 PF13847.6 KXZ45692.1 - 8.3e-27 93.9 0.0 1.4e-26 93.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ45692.1 - 4.8e-18 65.6 0.0 9.2e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ45692.1 - 6.5e-16 58.8 0.0 1.4e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ45692.1 - 4.4e-11 42.6 0.0 7.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXZ45692.1 - 1.6e-09 38.4 0.0 2.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ45692.1 - 3.3e-09 36.8 0.0 4.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXZ45692.1 - 1.7e-06 28.0 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KXZ45692.1 - 0.0029 17.7 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KXZ45692.1 - 0.0058 16.5 0.2 0.15 11.9 0.0 2.2 1 1 1 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.13 KXZ45692.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXZ45692.1 - 0.17 11.3 0.0 0.59 9.6 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.10 KXZ45692.1 - 0.17 11.4 0.0 0.64 9.6 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase TIP49 PF06068.13 KXZ45693.1 - 5.2e-168 558.7 0.0 6.8e-168 558.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXZ45693.1 - 2.6e-19 69.1 0.0 6.4e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KXZ45693.1 - 9.9e-11 41.6 0.1 1e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KXZ45693.1 - 4e-10 40.2 0.1 1.1e-06 29.0 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ45693.1 - 6.9e-07 29.6 0.0 0.037 14.3 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXZ45693.1 - 2.9e-05 24.5 0.1 0.00023 21.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KXZ45693.1 - 8.2e-05 23.0 0.9 0.13 12.6 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXZ45693.1 - 0.00053 20.3 0.1 0.0011 19.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXZ45693.1 - 0.00056 19.9 0.1 0.031 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXZ45693.1 - 0.00066 19.3 0.1 0.0026 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KXZ45693.1 - 0.0041 16.8 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KXZ45693.1 - 0.0052 16.2 0.2 0.14 11.5 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KXZ45693.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXZ45693.1 - 0.015 15.2 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXZ45693.1 - 0.019 15.5 0.0 0.047 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain DnaB_C PF03796.15 KXZ45693.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.9 KXZ45693.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KXZ45693.1 - 0.042 14.0 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXZ45693.1 - 0.057 13.1 0.2 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXZ45693.1 - 0.068 13.2 0.0 8.9 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KXZ45693.1 - 0.074 13.1 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KXZ45693.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein GvpD PF07088.11 KXZ45693.1 - 0.083 11.5 0.1 0.35 9.4 0.0 1.8 2 0 0 2 2 2 0 GvpD gas vesicle protein AAA_7 PF12775.7 KXZ45693.1 - 0.13 11.7 0.1 0.48 9.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KXZ45693.1 - 0.21 10.6 0.1 0.37 9.8 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UbiA PF01040.18 KXZ45694.1 - 2.1e-38 132.0 25.4 2.4e-37 128.6 25.4 1.9 1 1 0 1 1 1 1 UbiA prenyltransferase family BTB PF00651.31 KXZ45695.1 - 3.3e-15 56.3 0.0 5.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NHL PF01436.21 KXZ45695.1 - 0.00043 20.2 0.3 1 9.5 0.1 2.6 2 0 0 2 2 2 2 NHL repeat Rad21_Rec8_N PF04825.13 KXZ45696.1 - 1.4e-22 80.0 0.0 2.8e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXZ45696.1 - 2.1e-05 23.7 0.0 6.2e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TIR_2 PF13676.6 KXZ45697.1 - 0.066 13.8 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 TIR domain RINT1_TIP1 PF04437.13 KXZ45699.1 - 4.2e-16 58.9 0.0 2.2e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 RINT-1 / TIP-1 family Pkinase_Tyr PF07714.17 KXZ45700.1 - 2.7e-41 141.6 0.0 5.8e-32 111.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ45700.1 - 1.5e-32 113.0 0.0 2.2e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ45700.1 - 0.0022 16.9 0.2 0.0033 16.3 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KXZ45702.1 - 1.1e-37 129.8 0.0 1.6e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45702.1 - 6.2e-13 48.6 0.0 3.2e-05 23.4 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Ank_4 PF13637.6 KXZ45703.1 - 3.7e-13 49.7 1.3 0.072 13.7 0.0 7.1 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45703.1 - 1.1e-12 48.3 0.0 0.023 15.3 0.0 5.1 4 2 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ45703.1 - 1.6e-09 37.8 3.3 4.1 7.8 0.0 7.4 4 3 5 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45703.1 - 7.6e-07 29.0 2.9 25 5.9 0.0 9.3 10 1 1 11 11 11 1 Ankyrin repeat Pkinase PF00069.25 KXZ45704.1 - 2.7e-47 161.4 0.0 1.8e-25 89.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain DUF971 PF06155.12 KXZ45704.1 - 1.4e-21 76.9 0.0 2.5e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Pkinase_Tyr PF07714.17 KXZ45704.1 - 1.8e-21 76.6 0.0 4.6e-09 35.9 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase DUF2237 PF09996.9 KXZ45705.1 - 0.076 13.0 0.2 0.93 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2237) DAG1 PF05454.11 KXZ45705.1 - 0.25 10.7 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RhlB PF12300.8 KXZ45705.1 - 6.4 6.9 10.4 11 6.1 10.4 1.4 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB HSP70 PF00012.20 KXZ45707.1 - 5.4e-62 209.8 1.5 1.6e-31 109.2 0.0 4.2 4 1 0 4 4 4 3 Hsp70 protein MreB_Mbl PF06723.13 KXZ45707.1 - 4.2e-11 42.2 3.8 5.9e-07 28.6 0.1 3.2 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 KXZ45707.1 - 0.0046 17.3 0.1 0.7 10.4 0.0 2.9 2 2 0 2 2 2 1 Cell division protein FtsA StbA PF06406.11 KXZ45707.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 StbA protein Guanylate_cyc PF00211.20 KXZ45709.1 - 4.1e-41 140.6 0.1 5.7e-41 140.2 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Response_reg PF00072.24 KXZ45709.1 - 3.7e-23 81.8 0.0 7e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain bZIP_1 PF00170.21 KXZ45710.1 - 3e-08 33.6 9.9 3e-08 33.6 9.9 2.7 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ45710.1 - 0.0013 18.7 9.2 0.0013 18.7 9.2 2.5 2 0 0 2 2 2 1 Basic region leucine zipper N-SET PF11764.8 KXZ45710.1 - 0.018 15.2 3.7 0.039 14.0 3.7 1.5 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N CENP-F_leu_zip PF10473.9 KXZ45710.1 - 0.02 14.9 4.6 0.02 14.9 4.6 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RasGEF PF00617.19 KXZ45710.1 - 0.047 13.9 0.1 0.071 13.3 0.1 1.2 1 0 0 1 1 1 0 RasGEF domain Rotamase PF00639.21 KXZ45710.1 - 0.24 12.4 3.0 0.29 12.1 1.0 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain TFIIA PF03153.13 KXZ45711.1 - 4.1e-05 23.8 22.0 4.6e-05 23.6 22.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 KXZ45711.1 - 0.01 14.9 52.4 0.017 14.1 52.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UvrD_C PF13361.6 KXZ45711.1 - 0.049 13.0 0.5 0.061 12.7 0.5 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Pex14_N PF04695.13 KXZ45711.1 - 0.096 13.3 18.9 0.36 11.5 17.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_23 PF13476.6 KXZ45711.1 - 1.4 9.4 10.1 2.4 8.6 10.1 1.3 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 KXZ45711.1 - 2.1 7.0 11.5 3.1 6.5 11.5 1.2 1 0 0 1 1 1 0 Presenilin FapA PF03961.13 KXZ45711.1 - 2.2 6.8 4.8 3.3 6.2 4.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SAE2 PF08573.10 KXZ45711.1 - 3.7 8.7 10.1 8.2 7.6 10.1 1.5 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus CCSAP PF15748.5 KXZ45711.1 - 4.3 7.4 13.5 6.5 6.8 13.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM222A PF15258.6 KXZ45711.1 - 8.2 5.4 26.4 12 4.9 26.4 1.2 1 0 0 1 1 1 0 Protein family of FAM222A Rad21_Rec8_N PF04825.13 KXZ45714.1 - 1.2e-33 115.5 0.0 2e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXZ45714.1 - 2.4e-07 29.9 0.0 5.3e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Neur_chan_LBD PF02931.23 KXZ45715.1 - 2.8e-07 30.2 0.0 5.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KXZ45715.1 - 0.00012 22.2 0.5 0.00012 22.2 0.5 2.2 3 0 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region Na_Ca_ex PF01699.24 KXZ45715.1 - 0.96 9.4 6.8 0.073 13.0 0.6 2.1 2 0 0 2 2 2 0 Sodium/calcium exchanger protein PMT_4TMC PF16192.5 KXZ45715.1 - 1.2 8.7 7.0 0.51 9.9 0.7 2.7 3 0 0 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase Histone PF00125.24 KXZ45716.1 - 5.4e-54 182.1 2.1 6e-54 181.9 2.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ45716.1 - 0.00014 22.1 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ45716.1 - 0.00036 20.6 0.1 0.0007 19.7 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KXZ45716.1 - 0.00065 20.3 1.5 0.00079 20.0 1.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KXZ45716.1 - 0.0055 17.0 0.8 0.0089 16.3 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ45716.1 - 0.0094 16.0 0.1 0.017 15.2 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit Pyr_redox_2 PF07992.14 KXZ45717.1 - 9e-15 54.7 0.0 2.7e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ45717.1 - 0.00091 19.7 0.7 0.0027 18.2 0.7 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Histone PF00125.24 KXZ45718.1 - 5.4e-54 182.1 2.1 6e-54 181.9 2.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ45718.1 - 0.00014 22.1 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ45718.1 - 0.00036 20.6 0.1 0.0007 19.7 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KXZ45718.1 - 0.00065 20.3 1.5 0.00079 20.0 1.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KXZ45718.1 - 0.0055 17.0 0.8 0.0089 16.3 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ45718.1 - 0.0094 16.0 0.1 0.017 15.2 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KXZ45719.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ45719.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ45719.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ45719.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ45719.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ45719.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ45719.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated PRKCSH PF07915.13 KXZ45720.1 - 1.5e-11 45.2 1.1 2.2e-11 44.6 1.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KXZ45720.1 - 2e-07 30.8 0.1 2.9e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein TPR_12 PF13424.6 KXZ45721.1 - 9.7e-65 214.8 65.2 1.2e-12 47.9 0.6 11.0 8 2 3 11 11 11 10 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ45721.1 - 1.8e-62 205.6 82.5 2.2e-09 36.9 0.1 14.7 16 0 0 16 16 15 11 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ45721.1 - 1.1e-12 48.0 32.8 5.9e-08 32.5 10.7 4.5 3 2 2 5 5 5 2 MalT-like TPR region TPR_1 PF00515.28 KXZ45721.1 - 4.8e-12 45.2 28.5 0.059 13.2 0.1 9.3 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ45721.1 - 3.6e-11 42.3 41.7 0.039 14.0 0.1 11.5 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ45721.1 - 1.2e-09 38.2 75.3 0.88 10.6 2.6 13.7 9 3 4 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ45721.1 - 1.9e-08 33.8 49.1 0.13 12.4 0.2 11.3 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ45721.1 - 1.2e-07 32.1 41.8 0.018 15.5 2.8 9.0 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ45721.1 - 3.3e-07 30.8 72.2 0.023 15.3 1.4 11.5 8 4 2 10 10 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ45721.1 - 0.0025 18.0 7.4 17 5.8 0.0 5.6 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXZ45721.1 - 0.0037 17.4 16.4 36 4.9 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat Urb2 PF10441.9 KXZ45721.1 - 0.012 15.5 5.3 10 6.0 0.0 4.9 3 1 1 4 4 4 0 Urb2/Npa2 family TPR_17 PF13431.6 KXZ45721.1 - 1.2 9.7 10.0 82 3.9 0.0 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Ank_2 PF12796.7 KXZ45722.1 - 0.02 15.5 0.2 0.054 14.1 0.2 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Serinc PF03348.15 KXZ45723.1 - 3.1e-102 342.7 0.6 3.4e-102 342.6 0.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2231 PF09990.9 KXZ45723.1 - 0.082 13.4 0.2 0.082 13.4 0.2 3.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Nucleotid_trans PF03407.16 KXZ45724.1 - 1e-17 64.8 0.0 1.5e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Pam16 PF03656.13 KXZ45725.1 - 2.5e-24 85.7 3.9 3.6e-24 85.2 3.9 1.3 1 1 0 1 1 1 1 Pam16 POTRA PF07244.15 KXZ45725.1 - 0.065 13.8 0.9 0.1 13.2 0.9 1.2 1 0 0 1 1 1 0 Surface antigen variable number repeat SUIM_assoc PF16619.5 KXZ45725.1 - 1.9 8.6 13.0 3.1 7.9 13.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2849 PF11011.8 KXZ45725.1 - 4.1 8.1 9.8 0.31 11.7 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) 2OG-FeII_Oxy_2 PF13532.6 KXZ45726.1 - 2.8e-43 148.4 0.0 5e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2HC5 PF06221.13 KXZ45726.1 - 0.071 13.1 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Exostosin PF03016.15 KXZ45728.1 - 2.6e-19 69.6 0.0 3e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 Exostosin family DUF563 PF04577.14 KXZ45728.1 - 1.7e-12 47.9 1.2 4.7e-12 46.5 1.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) BTB PF00651.31 KXZ45729.1 - 0.016 15.4 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain API5 PF05918.11 KXZ45730.1 - 6.9 5.4 4.8 10 4.8 4.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SHMT PF00464.19 KXZ45731.1 - 6.1e-194 644.2 0.0 7.2e-194 643.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KXZ45731.1 - 1.5e-07 30.9 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_127 PF07944.12 KXZ45731.1 - 0.034 12.7 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Aminotran_5 PF00266.19 KXZ45731.1 - 0.046 12.7 0.3 0.38 9.7 0.3 2.1 1 1 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXZ45731.1 - 0.046 13.0 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TPR_9 PF13371.6 KXZ45732.1 - 4.2e-08 33.2 16.7 0.0037 17.4 0.8 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ45732.1 - 4.9e-08 32.5 9.0 0.079 13.1 1.4 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ45732.1 - 6.6e-08 33.0 3.5 0.00091 19.7 0.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ45732.1 - 1.6e-05 24.5 6.9 0.0056 16.5 0.4 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ45732.1 - 3.8e-05 24.2 20.9 0.78 10.7 0.1 5.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45732.1 - 0.00024 21.1 4.0 19 5.8 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ45732.1 - 0.00064 20.0 17.2 0.0016 18.7 1.7 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ45732.1 - 0.0022 18.6 26.1 0.094 13.4 1.5 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ45732.1 - 0.02 14.6 1.7 1.4 8.7 0.1 3.6 3 1 1 4 4 4 0 TPR repeat TPR_15 PF13429.6 KXZ45732.1 - 0.023 13.9 3.6 1.6 7.9 0.5 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXZ45732.1 - 0.025 14.0 0.2 2 7.9 0.1 2.7 3 0 0 3 3 3 0 SHNi-TPR TPR_10 PF13374.6 KXZ45732.1 - 0.046 13.6 0.1 0.046 13.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ45732.1 - 0.087 13.5 6.5 8.7 7.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ45732.1 - 0.12 13.1 1.5 0.12 13.1 1.5 4.8 4 1 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 KXZ45732.1 - 0.13 12.4 0.6 2.5 8.2 0.1 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KXZ45732.1 - 0.17 12.0 6.9 24 5.2 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat COesterase PF00135.28 KXZ45733.1 - 2.6e-79 267.4 0.0 2.8e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXZ45733.1 - 4.2e-07 30.0 2.9 0.0087 15.9 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXZ45733.1 - 0.0026 17.3 0.4 0.0044 16.5 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KXZ45734.1 - 1e-80 272.1 0.0 1.1e-80 271.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXZ45734.1 - 5e-08 33.0 2.9 0.0073 16.2 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold GATase_5 PF13507.6 KXZ45734.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Myb_DNA-binding PF00249.31 KXZ45735.1 - 9.7e-07 28.9 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ45735.1 - 0.00063 19.9 0.1 0.0015 18.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Abhydrolase_1 PF00561.20 KXZ45736.1 - 4.8e-10 39.5 0.0 1e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ45736.1 - 5.1e-06 25.9 0.3 0.00013 21.4 0.0 2.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXZ45736.1 - 2.8e-05 22.9 0.0 5.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ilar_coat PF01787.16 KXZ45736.1 - 1.9 8.2 3.1 18 5.1 0.1 2.6 3 0 0 3 3 3 0 Ilarvirus coat protein PPR_3 PF13812.6 KXZ45737.1 - 0.0072 16.4 0.0 3.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 KXZ45737.1 - 0.01 16.0 0.2 0.18 12.1 0.0 2.7 2 1 0 2 2 2 0 PPR repeat Acid_PPase PF12689.7 KXZ45737.1 - 0.093 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase PPR_3 PF13812.6 KXZ45738.1 - 2e-05 24.6 0.0 0.002 18.1 0.0 2.4 1 1 1 2 2 2 2 Pentatricopeptide repeat domain DUF1843 PF08898.10 KXZ45738.1 - 0.012 16.1 0.1 10 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) PPR_long PF17177.4 KXZ45738.1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Ank_2 PF12796.7 KXZ45740.1 - 1.1e-32 112.4 4.7 4.1e-13 49.7 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45740.1 - 2e-24 85.6 1.6 8.5e-11 42.2 0.0 5.4 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ45740.1 - 1.5e-19 69.8 10.9 7e-05 23.0 0.1 5.7 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45740.1 - 1.8e-17 61.6 4.0 0.00029 21.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KXZ45740.1 - 2e-17 62.8 4.5 0.0005 20.4 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat U-box PF04564.15 KXZ45740.1 - 8.6e-13 48.3 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain SpoIIE PF07228.12 KXZ45741.1 - 3.5e-10 40.1 0.4 2.5e-09 37.3 0.3 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXZ45741.1 - 2.3e-05 24.1 0.5 5.5e-05 22.9 0.5 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KXZ45741.1 - 0.064 12.9 0.6 0.88 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C Hint PF01079.20 KXZ45742.1 - 4.2e-23 82.0 0.0 6.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Hint module EF-hand_1 PF00036.32 KXZ45742.1 - 0.0063 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ45742.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ45742.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Adeno_E4_ORF3 PF06931.11 KXZ45742.1 - 0.12 12.5 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein EF-hand_7 PF13499.6 KXZ45742.1 - 0.21 12.0 0.0 0.43 11.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Oleosin PF01277.17 KXZ45742.1 - 0.22 11.3 2.6 1.6 8.5 0.0 3.0 2 1 1 3 3 3 0 Oleosin Hint PF01079.20 KXZ45743.1 - 3.2e-19 69.3 0.0 5.2e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Hint module Spore_III_AF PF09581.10 KXZ45743.1 - 0.042 13.9 0.2 0.065 13.3 0.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) FxsA PF04186.13 KXZ45743.1 - 1.4 9.1 6.1 1.1 9.4 0.8 2.4 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein TRP PF06011.12 KXZ45744.1 - 2.8e-09 36.2 8.6 2.8e-09 36.2 8.6 2.3 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel DUF5562 PF17717.1 KXZ45744.1 - 0.15 12.1 4.6 0.39 10.7 4.6 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5562) ABC_tran PF00005.27 KXZ45745.1 - 6.9e-50 169.1 0.1 7.5e-26 91.3 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXZ45745.1 - 2.4e-19 70.3 1.0 4.8e-05 23.3 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KXZ45745.1 - 1.7e-11 44.0 5.0 2.1e-09 37.3 3.6 2.4 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KXZ45745.1 - 1.8e-05 25.4 2.3 0.043 14.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KXZ45745.1 - 1.8e-05 24.4 1.5 0.065 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXZ45745.1 - 2.2e-05 24.5 0.2 0.25 11.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KXZ45745.1 - 3.8e-05 24.0 0.4 0.015 15.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXZ45745.1 - 5.2e-05 22.8 2.8 5 6.5 0.0 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KXZ45745.1 - 0.00018 21.8 0.0 0.54 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KXZ45745.1 - 0.00055 20.0 0.0 0.061 13.4 0.0 2.6 3 0 0 3 3 2 1 Dynamin family ATP-synt_ab PF00006.25 KXZ45745.1 - 0.0012 18.6 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 KXZ45745.1 - 0.0026 17.7 0.5 2.9 7.8 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 KXZ45745.1 - 0.0029 17.8 2.0 9 6.6 0.0 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KXZ45745.1 - 0.0035 17.9 1.1 1.9 9.1 0.3 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXZ45745.1 - 0.0044 17.2 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain MukB PF04310.12 KXZ45745.1 - 0.0087 15.9 0.9 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 MukB N-terminal AAA_30 PF13604.6 KXZ45745.1 - 0.0097 15.6 2.5 2.4 7.8 0.7 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ45745.1 - 0.017 15.5 2.1 2.5 8.4 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 KXZ45745.1 - 0.017 14.6 0.5 16 5.0 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KXZ45745.1 - 0.02 15.1 0.5 4.7 7.4 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KXZ45745.1 - 0.021 14.1 0.8 0.72 9.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 KXZ45745.1 - 0.027 14.4 0.9 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 KXZ45745.1 - 0.043 12.8 5.2 1.5 7.8 0.2 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KXZ45745.1 - 0.046 13.4 3.8 2.4 7.8 0.2 2.9 3 1 1 4 4 3 0 AAA domain AAA_15 PF13175.6 KXZ45745.1 - 0.064 12.9 1.8 4.6 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain AAA_13 PF13166.6 KXZ45745.1 - 0.1 11.2 7.0 2.1 6.9 0.0 3.5 5 0 0 5 5 4 0 AAA domain AAA_14 PF13173.6 KXZ45745.1 - 0.11 12.5 0.1 10 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KXZ45745.1 - 0.12 11.5 3.1 0.84 8.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KXZ45745.1 - 0.13 12.6 0.2 12 6.3 0.1 2.3 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 KXZ45745.1 - 0.26 10.9 0.6 6.8 6.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 KXZ45745.1 - 0.65 9.6 4.1 15 5.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.9 KXZ45745.1 - 1.4 7.7 3.1 5.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF87 PF01935.17 KXZ45745.1 - 3.5 7.7 10.8 2.9 7.9 1.8 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain DOT1 PF08123.13 KXZ45746.1 - 2.8e-14 53.1 0.0 4.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 KXZ45746.1 - 0.071 12.4 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KXZ45746.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Lum_binding PF00677.17 KXZ45747.1 - 1.2e-46 156.6 1.5 1.5e-22 79.4 0.0 2.3 2 0 0 2 2 2 2 Lumazine binding domain ASH PF15780.5 KXZ45748.1 - 1.4e-24 86.2 0.3 0.28 11.4 0.0 12.3 14 0 0 14 14 14 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KXZ45748.1 - 2.8e-07 30.6 2.0 0.11 12.6 0.0 6.0 6 0 0 6 6 6 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KXZ45748.1 - 3.9e-06 26.7 0.0 4.6 7.1 0.0 5.1 4 0 0 4 4 4 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KXZ45748.1 - 0.001 19.3 0.8 6.9 7.0 0.0 5.3 6 0 0 6 6 6 1 Transmembrane protein 131-like Stathmin PF00836.19 KXZ45748.1 - 0.0036 17.3 0.8 0.0072 16.3 0.8 1.4 1 0 0 1 1 1 1 Stathmin family A2M_BRD PF07703.14 KXZ45748.1 - 0.13 12.6 0.0 23 5.3 0.0 3.6 4 0 0 4 4 4 0 Alpha-2-macroglobulin bait region domain DUF4351 PF14261.6 KXZ45748.1 - 4.7 7.4 4.4 51 4.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) Lipase_GDSL_2 PF13472.6 KXZ45750.1 - 4.3e-08 33.7 0.1 2.7e-07 31.1 0.1 2.3 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXZ45750.1 - 0.0037 17.3 0.0 0.46 10.4 0.0 2.9 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase AAA_12 PF13087.6 KXZ45751.1 - 6.8e-55 185.8 0.0 8.8e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ45751.1 - 4.3e-45 154.5 0.3 3.8e-26 92.5 0.4 2.1 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KXZ45751.1 - 1.5e-10 41.1 4.9 4.6e-09 36.3 4.9 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ45751.1 - 7.8e-09 36.0 0.0 1.7e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ45751.1 - 0.00012 21.9 0.0 0.23 11.2 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KXZ45751.1 - 0.0011 18.5 0.0 0.6 9.5 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein UvrD_C_2 PF13538.6 KXZ45751.1 - 0.0063 16.3 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain P3A PF08727.11 KXZ45752.1 - 0.0098 15.2 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Poliovirus 3A protein like Pkinase PF00069.25 KXZ45753.1 - 5e-19 68.7 0.0 3.2e-09 36.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45753.1 - 2.7e-11 43.2 0.0 2.3e-06 27.1 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ45754.1 - 9.3e-21 74.4 0.0 1.1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45754.1 - 1.1e-18 67.4 0.0 1.4e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ45754.1 - 0.17 11.8 5.5 0.92 9.4 5.5 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ45755.1 - 5.1e-09 35.8 0.0 6e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ45755.1 - 1.2e-08 34.6 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain 2-Hacid_dh_C PF02826.19 KXZ45756.1 - 1e-47 161.8 0.2 1e-46 158.6 0.2 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXZ45756.1 - 1.9e-16 59.9 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 KXZ45756.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXZ45756.1 - 0.012 16.1 0.1 0.051 14.0 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 KXZ45756.1 - 0.012 15.2 0.4 3.1 7.3 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KXZ45756.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXZ45756.1 - 0.029 14.9 0.0 0.093 13.3 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KXZ45756.1 - 0.031 15.1 0.1 3 8.7 0.0 2.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 KXZ45756.1 - 0.038 14.1 0.1 0.12 12.5 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXZ45756.1 - 0.088 12.7 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.20 KXZ45756.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Mito_carr PF00153.27 KXZ45757.1 - 4.4e-07 29.7 0.0 9e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial carrier protein Mito_carr PF00153.27 KXZ45758.1 - 6.8e-17 61.2 0.0 7.6e-17 61.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein FAD_binding_7 PF03441.14 KXZ45759.1 - 9.7e-62 208.0 1.8 3.7e-61 206.1 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXZ45759.1 - 1.3e-25 90.3 0.0 2.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase PAP2 PF01569.21 KXZ45760.1 - 4.3e-08 33.0 11.3 1.3e-07 31.5 6.5 3.0 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KXZ45760.1 - 8e-05 22.8 0.4 0.0064 16.6 0.0 2.6 1 1 2 3 3 3 1 Divergent PAP2 family Zip PF02535.22 KXZ45760.1 - 0.072 12.3 0.3 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter H_PPase PF03030.16 KXZ45760.1 - 0.14 10.8 0.8 0.18 10.4 0.8 1.2 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase PHO4 PF01384.20 KXZ45760.1 - 0.29 10.1 4.2 0.3 10.1 0.3 2.0 2 0 0 2 2 2 0 Phosphate transporter family F-box-like PF12937.7 KXZ45761.1 - 0.02 14.8 1.1 0.046 13.6 1.1 1.6 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KXZ45761.1 - 0.098 13.1 2.7 30 5.2 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF2389 PF09493.10 KXZ45765.1 - 2.5e-21 76.0 1.3 4e-21 75.4 1.3 1.3 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) NAD_binding_10 PF13460.6 KXZ45766.1 - 5e-33 114.5 0.5 5e-33 114.5 0.5 2.9 3 0 0 3 3 3 1 NAD(P)H-binding NmrA PF05368.13 KXZ45766.1 - 2.5e-08 33.8 0.1 6.3e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXZ45766.1 - 0.0013 18.2 0.5 0.0057 16.2 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ45766.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Spc7 PF08317.11 KXZ45766.1 - 3 6.7 8.2 4.8 6.0 8.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Acetyltransf_1 PF00583.25 KXZ45767.1 - 1.7e-09 37.9 0.0 2.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ45767.1 - 2e-08 34.2 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ45767.1 - 0.00042 20.2 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXZ45767.1 - 0.0012 19.2 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXZ45767.1 - 0.0054 16.5 0.1 0.0094 15.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Malic_M PF03949.15 KXZ45769.1 - 1.5e-85 286.6 0.0 1.9e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXZ45769.1 - 1.4e-44 152.0 0.0 2.2e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TPR_19 PF14559.6 KXZ45770.1 - 2.8e-40 136.7 60.8 0.00052 20.5 0.0 18.4 15 3 4 19 19 19 11 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ45770.1 - 5.6e-37 123.3 50.1 0.0097 16.7 0.0 23.4 14 8 11 25 25 24 8 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ45770.1 - 1.6e-32 111.9 30.9 0.00022 21.8 0.4 16.4 14 3 4 18 18 17 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ45770.1 - 2.8e-32 108.2 50.0 0.0012 18.8 0.0 20.9 23 0 0 23 23 22 8 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ45770.1 - 5.6e-20 70.3 38.2 3.1e-05 23.6 0.0 14.3 16 0 0 16 16 12 6 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ45770.1 - 7.5e-17 60.4 9.8 0.15 12.5 0.0 13.3 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45770.1 - 2.6e-16 58.4 25.4 0.00075 19.5 0.2 14.3 17 0 0 17 17 15 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ45770.1 - 1.8e-10 40.1 19.3 0.31 11.2 0.0 11.1 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_21 PF09976.9 KXZ45770.1 - 2.3e-10 40.5 29.9 0.0071 16.1 2.8 7.2 5 2 1 6 6 6 3 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 KXZ45770.1 - 5.4e-10 39.4 32.1 0.0051 17.0 1.2 10.7 9 4 4 14 14 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KXZ45770.1 - 2e-07 30.6 14.4 0.046 13.4 0.1 10.7 13 2 2 15 15 12 2 TPR repeat TPR_12 PF13424.6 KXZ45770.1 - 2.2e-07 31.1 53.5 0.023 15.0 0.0 15.2 11 4 10 21 21 20 6 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ45770.1 - 5.4e-07 29.8 40.3 0.38 11.5 0.0 16.0 22 0 0 22 22 15 2 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ45770.1 - 8.1e-07 29.3 36.2 0.13 12.6 0.1 12.7 11 5 4 15 15 13 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KXZ45770.1 - 2.8e-05 23.0 8.7 0.0081 14.9 0.0 5.4 6 0 0 6 6 6 2 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 KXZ45770.1 - 0.015 15.9 31.1 1.6 9.6 0.2 12.0 12 0 0 12 12 11 0 Tetratricopeptide repeat FmrO PF07091.11 KXZ45770.1 - 0.038 13.5 1.9 0.42 10.1 0.3 3.3 3 0 0 3 3 3 0 Ribosomal RNA methyltransferase (FmrO) YfiO PF13525.6 KXZ45770.1 - 0.08 12.7 3.5 1.2 8.8 0.2 4.2 4 0 0 4 4 4 0 Outer membrane lipoprotein HrpB1_HrpK PF09613.10 KXZ45770.1 - 0.093 12.4 0.0 0.093 12.4 0.0 7.7 9 1 0 9 9 8 0 Bacterial type III secretion protein (HrpB1_HrpK) PriCT_2 PF08707.11 KXZ45770.1 - 0.11 12.8 0.1 0.75 10.2 0.1 2.3 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Fis1_TPR_C PF14853.6 KXZ45770.1 - 0.15 12.1 12.7 2.5 8.3 0.0 6.5 7 1 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KXZ45770.1 - 0.4 9.6 6.3 4.8 6.1 0.1 3.9 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) HEPN PF05168.14 KXZ45770.1 - 0.68 10.1 4.6 1.2 9.3 0.1 3.9 5 0 0 5 5 3 0 HEPN domain Alkyl_sulf_dimr PF14863.6 KXZ45770.1 - 2.1 8.8 13.4 18 5.8 0.1 6.6 6 1 0 6 6 6 0 Alkyl sulfatase dimerisation TPR_9 PF13371.6 KXZ45770.1 - 2.1 8.6 30.5 1.6 9.0 0.0 9.5 10 2 2 12 12 9 0 Tetratricopeptide repeat MIT PF04212.18 KXZ45770.1 - 2.5 8.3 14.5 15 5.7 0.0 6.4 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain RAMA PF18755.1 KXZ45772.1 - 1.5e-11 44.6 0.0 5.2e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated AAA_23 PF13476.6 KXZ45772.1 - 0.12 12.8 3.8 0.19 12.2 3.8 1.2 1 0 0 1 1 1 0 AAA domain DUF2722 PF10846.8 KXZ45772.1 - 0.74 8.7 12.4 0.028 13.4 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) MlaE PF02405.16 KXZ45773.1 - 2.4e-69 233.3 18.0 2.4e-69 233.3 18.0 2.5 3 0 0 3 3 3 1 Permease MlaE Pkinase PF00069.25 KXZ45774.1 - 1.8e-62 211.1 0.1 3.5e-62 210.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45774.1 - 1e-42 146.3 0.1 2.2e-42 145.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ45774.1 - 0.00015 21.2 0.0 0.0048 16.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXZ45774.1 - 0.48 9.1 2.7 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Trypsin PF00089.26 KXZ45775.1 - 1.3e-11 44.7 0.1 5e-11 42.8 0.1 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KXZ45775.1 - 1.8e-08 35.4 3.0 1.1e-07 32.9 0.3 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain Sporozoite_P67 PF05642.11 KXZ45775.1 - 0.17 9.9 3.8 0.6 8.1 3.2 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mito_carr PF00153.27 KXZ45776.1 - 9.2e-46 153.7 3.6 3.1e-22 78.3 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Scramblase PF03803.15 KXZ45777.1 - 2e-41 141.7 0.0 3.3e-41 141.0 0.0 1.3 1 1 0 1 1 1 1 Scramblase MAP65_ASE1 PF03999.12 KXZ45777.1 - 0.012 14.3 1.0 0.017 13.9 1.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) LOR PF04525.12 KXZ45777.1 - 0.22 11.1 0.0 3.2 7.3 0.0 2.4 2 1 1 3 3 3 0 LURP-one-related Spt20 PF12090.8 KXZ45777.1 - 2.6 7.6 14.0 3.9 7.0 14.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF3883 PF13020.6 KXZ45779.1 - 1.9e-14 53.5 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) DUF874 PF05917.11 KXZ45780.1 - 0.13 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) LPP PF04728.13 KXZ45781.1 - 0.0004 20.7 0.5 0.38 11.2 0.1 2.1 1 1 1 2 2 2 2 Lipoprotein leucine-zipper DUF4201 PF13870.6 KXZ45781.1 - 0.00055 19.7 0.3 0.00061 19.6 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) YscO PF07321.12 KXZ45781.1 - 0.002 18.1 1.3 0.0023 17.9 1.3 1.1 1 0 0 1 1 1 1 Type III secretion protein YscO YscO-like PF16789.5 KXZ45781.1 - 0.0038 17.3 0.3 0.0045 17.0 0.3 1.1 1 0 0 1 1 1 1 YscO-like protein Filament PF00038.21 KXZ45781.1 - 0.0042 16.7 0.9 0.0048 16.5 0.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 KXZ45781.1 - 0.0059 15.5 0.8 0.0064 15.4 0.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KXZ45781.1 - 0.0069 16.4 0.7 0.0089 16.1 0.7 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 KXZ45781.1 - 0.0073 16.7 0.5 0.8 10.2 0.0 2.1 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 KXZ45781.1 - 0.0076 15.9 0.4 0.013 15.2 0.4 1.4 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 KXZ45781.1 - 0.0083 16.2 0.1 0.02 14.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Atg14 PF10186.9 KXZ45781.1 - 0.025 13.7 0.9 0.028 13.5 0.9 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 KXZ45781.1 - 0.029 13.0 0.2 0.033 12.9 0.2 1.0 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 KXZ45781.1 - 0.031 14.8 0.3 0.037 14.5 0.3 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 KXZ45781.1 - 0.032 14.1 0.0 0.035 13.9 0.0 1.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 KXZ45781.1 - 0.032 14.7 0.0 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 KXZ45781.1 - 0.033 14.3 0.8 0.19 11.8 0.8 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FmiP_Thoc5 PF09766.9 KXZ45781.1 - 0.042 13.1 0.1 0.049 12.9 0.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 EzrA PF06160.12 KXZ45781.1 - 0.042 12.0 0.2 0.042 12.0 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TACC_C PF05010.14 KXZ45781.1 - 0.046 13.5 0.1 0.05 13.4 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlgM PF04316.13 KXZ45781.1 - 0.048 14.0 1.0 0.083 13.3 0.4 1.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Laminin_II PF06009.12 KXZ45781.1 - 0.048 13.7 0.6 0.071 13.1 0.6 1.3 1 1 0 1 1 1 0 Laminin Domain II Fez1 PF06818.15 KXZ45781.1 - 0.053 14.0 0.5 0.06 13.8 0.5 1.0 1 0 0 1 1 1 0 Fez1 Golgin_A5 PF09787.9 KXZ45781.1 - 0.055 12.9 0.4 0.058 12.9 0.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 ADIP PF11559.8 KXZ45781.1 - 0.06 13.4 0.4 0.067 13.3 0.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Gp58 PF07902.11 KXZ45781.1 - 0.065 11.5 0.3 0.07 11.4 0.3 1.1 1 0 0 1 1 1 0 gp58-like protein COG5 PF10392.9 KXZ45781.1 - 0.075 13.2 0.3 0.11 12.6 0.3 1.4 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Syntaxin-6_N PF09177.11 KXZ45781.1 - 0.076 13.6 0.9 0.18 12.3 0.9 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Med9 PF07544.13 KXZ45781.1 - 0.081 13.0 0.2 0.12 12.5 0.2 1.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 KXZ45781.1 - 0.13 12.5 0.1 0.59 10.4 0.1 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KXZ45781.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 KXZ45782.1 - 0.0062 15.7 0.2 0.0068 15.5 0.2 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin-6_N PF09177.11 KXZ45782.1 - 0.0065 17.0 0.8 0.33 11.5 0.2 2.1 1 1 1 2 2 2 1 Syntaxin 6, N-terminal Spc7 PF08317.11 KXZ45782.1 - 0.01 14.8 0.2 0.011 14.7 0.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 KXZ45782.1 - 0.026 14.9 0.2 0.83 10.1 0.1 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper YscO-like PF16789.5 KXZ45782.1 - 0.032 14.3 0.1 0.034 14.2 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein FlaC_arch PF05377.11 KXZ45782.1 - 0.048 14.1 0.2 0.87 10.0 0.1 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.6 KXZ45782.1 - 0.056 13.2 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) FlgM PF04316.13 KXZ45782.1 - 0.062 13.7 0.4 0.091 13.1 0.4 1.3 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM FmiP_Thoc5 PF09766.9 KXZ45782.1 - 0.071 12.4 0.0 0.079 12.2 0.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 COG5 PF10392.9 KXZ45782.1 - 0.094 12.9 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 COG2 PF06148.11 KXZ45782.1 - 0.094 12.8 0.5 0.16 12.1 0.5 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GP20 PF06810.11 KXZ45782.1 - 0.13 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Pkinase PF00069.25 KXZ45785.1 - 4.6e-39 134.4 0.0 7.6e-19 68.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45785.1 - 2.4e-08 33.6 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Spc7 PF08317.11 KXZ45786.1 - 0.00064 18.7 13.6 0.00064 18.7 13.6 6.4 3 2 3 6 6 6 3 Spc7 kinetochore protein Spc29 PF17082.5 KXZ45786.1 - 0.0026 17.7 3.7 0.0026 17.7 3.7 4.1 2 2 1 3 3 3 1 Spindle Pole Component 29 CENP-F_leu_zip PF10473.9 KXZ45786.1 - 0.014 15.4 0.7 0.014 15.4 0.7 9.3 3 1 6 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KXZ45786.1 - 0.019 15.0 1.2 0.019 15.0 1.2 7.1 6 2 2 8 8 8 0 Protein of unknown function (DUF1664) YabA PF06156.13 KXZ45786.1 - 0.64 10.7 0.1 0.64 10.7 0.1 8.3 4 2 3 8 8 8 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 KXZ45787.1 - 0.0058 16.2 2.3 0.0058 16.2 2.3 3.3 2 1 0 2 2 2 1 Exonuclease VII, large subunit AAA_23 PF13476.6 KXZ45787.1 - 0.065 13.7 0.3 0.065 13.7 0.3 3.6 2 1 0 2 2 2 0 AAA domain EIF4E-T PF10477.9 KXZ45787.1 - 0.2 10.5 14.2 0.67 8.7 14.1 1.8 1 1 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1980 PF09323.10 KXZ45787.1 - 4.6 7.1 8.2 0.64 9.9 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Methyltransf_21 PF05050.12 KXZ45788.1 - 3.2e-05 24.0 0.0 5.2e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain PCMT PF01135.19 KXZ45788.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KXZ45788.1 - 0.0052 16.9 0.0 0.0075 16.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 KXZ45788.1 - 0.047 13.4 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein V_cholerae_RfbT PF05575.11 KXZ45788.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein DUF1365 PF07103.11 KXZ45789.1 - 5.2e-34 118.0 0.0 6.8e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) AKAP7_NLS PF10469.9 KXZ45790.1 - 2.5e-12 47.1 0.0 7.9e-05 22.6 0.4 4.0 4 0 0 4 4 4 3 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KXZ45790.1 - 1.4e-05 25.0 1.8 0.00017 21.6 0.1 3.1 2 1 0 2 2 2 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KXZ45790.1 - 0.00066 19.8 0.9 0.0031 17.7 0.1 2.6 3 0 0 3 3 3 1 LigT like Phosphoesterase Glycos_transf_2 PF00535.26 KXZ45791.1 - 1.6e-17 63.9 0.0 5.4e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXZ45791.1 - 2.2e-16 60.4 0.0 3.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXZ45791.1 - 4.2e-12 46.4 19.3 2.4e-11 43.9 19.3 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 KXZ45791.1 - 0.011 14.3 3.5 0.017 13.6 3.5 1.2 1 0 0 1 1 1 0 Cellulose synthase Chitin_synth_2 PF03142.15 KXZ45791.1 - 0.063 11.9 0.7 0.32 9.5 0.0 2.2 3 0 0 3 3 3 0 Chitin synthase IHABP4_N PF16174.5 KXZ45791.1 - 0.28 11.8 3.6 0.48 11.0 3.6 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal LRR_9 PF14580.6 KXZ45792.1 - 2.6e-15 56.4 1.6 1.3e-14 54.1 2.0 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KXZ45792.1 - 1.4e-10 41.2 12.9 2.9e-05 24.3 1.4 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ45792.1 - 5.9e-06 26.0 8.6 0.013 15.2 1.2 2.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KXZ45792.1 - 0.02 15.4 10.7 5.2 8.0 0.4 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat CSD PF00313.22 KXZ45793.1 - 1.3e-26 92.2 0.2 2.1e-26 91.5 0.2 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain RRM_1 PF00076.22 KXZ45793.1 - 2.1e-18 65.9 0.0 8.7e-18 63.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KXZ45793.1 - 6.4e-05 22.6 0.0 0.0003 20.4 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 KXZ45793.1 - 0.0017 18.4 0.0 0.0061 16.6 0.0 1.9 1 1 0 1 1 1 1 Limkain b1 RRM_3 PF08777.11 KXZ45793.1 - 0.0088 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif TEX12 PF15219.6 KXZ45794.1 - 0.0078 16.5 3.8 0.5 10.7 1.0 3.8 3 0 0 3 3 3 2 Testis-expressed 12 Ras PF00071.22 KXZ45795.1 - 2.6e-35 121.4 0.0 3.1e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ45795.1 - 1.2e-16 61.0 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ45795.1 - 0.00036 20.0 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ECR1_N PF14382.6 KXZ45796.1 - 0.04 13.7 0.2 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Pkinase PF00069.25 KXZ45796.1 - 0.27 10.6 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain EF-hand_7 PF13499.6 KXZ45797.1 - 1.3e-162 528.5 0.2 6.2e-10 39.4 0.0 20.7 20 0 0 20 20 20 19 EF-hand domain pair EF-hand_1 PF00036.32 KXZ45797.1 - 1.5e-131 418.5 7.6 0.00021 20.6 0.2 36.9 38 0 0 38 38 38 26 EF hand EF-hand_6 PF13405.6 KXZ45797.1 - 9.2e-125 396.2 22.9 0.00064 19.5 0.0 37.2 37 0 0 37 37 37 27 EF-hand domain EF-hand_5 PF13202.6 KXZ45797.1 - 3.6e-87 282.3 20.7 0.00039 19.8 0.0 27.9 28 0 0 28 28 28 20 EF hand EF-hand_8 PF13833.6 KXZ45797.1 - 3.9e-48 161.1 25.6 0.026 14.4 0.0 26.9 23 6 5 28 28 28 9 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXZ45797.1 - 1.6e-15 57.4 0.0 39 4.6 0.0 14.7 15 1 0 15 15 15 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KXZ45797.1 - 4.5e-13 48.8 9.0 0.66 9.9 0.0 12.4 14 0 0 14 14 14 2 EF hand EF-hand_9 PF14658.6 KXZ45797.1 - 3.6e-08 33.6 0.3 0.51 10.7 0.0 8.5 10 0 0 10 10 9 1 EF-hand domain Caleosin PF05042.13 KXZ45797.1 - 2.6e-07 30.7 0.1 1.4e+02 2.3 0.0 11.3 14 0 0 14 14 14 0 Caleosin related protein EF-hand_4 PF12763.7 KXZ45797.1 - 0.0002 21.2 0.0 2.9 7.9 0.0 6.5 8 0 0 8 8 7 1 Cytoskeletal-regulatory complex EF hand RHH_4 PF13467.6 KXZ45797.1 - 0.028 14.3 1.5 2.5 8.0 0.2 3.6 3 0 0 3 3 3 0 Ribbon-helix-helix domain Beta-lactamase2 PF13354.6 KXZ45797.1 - 0.054 13.1 0.1 17 4.9 0.0 4.5 4 0 0 4 4 4 0 Beta-lactamase enzyme family SH3_11 PF18103.1 KXZ45797.1 - 0.055 13.6 1.4 0.15 12.3 0.1 2.3 2 0 0 2 2 2 0 Retroviral integrase C-terminal SH3 domain EF-hand_7 PF13499.6 KXZ45798.1 - 1.1e-33 115.4 0.3 1.5e-11 44.6 0.0 7.7 7 1 0 7 7 7 5 EF-hand domain pair EF-hand_6 PF13405.6 KXZ45798.1 - 5.6e-25 85.1 15.0 0.019 14.9 0.0 11.6 12 1 1 13 13 13 6 EF-hand domain EF-hand_1 PF00036.32 KXZ45798.1 - 9.4e-25 84.3 9.3 0.0006 19.2 0.0 10.9 12 1 1 13 13 13 5 EF hand EF-hand_5 PF13202.6 KXZ45798.1 - 5.3e-15 54.1 20.0 0.0013 18.1 0.0 8.9 10 0 0 10 10 10 4 EF hand EF-hand_8 PF13833.6 KXZ45798.1 - 5.8e-14 51.7 0.5 0.0085 15.9 0.0 7.9 8 2 0 8 8 8 3 EF-hand domain pair Dockerin_1 PF00404.18 KXZ45798.1 - 0.0025 17.9 0.1 1.6 9.0 0.0 4.0 4 0 0 4 4 4 1 Dockerin type I domain YL1_C PF08265.11 KXZ45798.1 - 6 6.7 9.1 7.2 6.5 0.1 3.7 4 0 0 4 4 4 0 YL1 nuclear protein C-terminal domain EF-hand_7 PF13499.6 KXZ45799.1 - 6.6e-29 100.2 0.0 9.7e-10 38.8 0.0 3.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 KXZ45799.1 - 1.1e-21 74.7 0.0 0.00067 19.0 0.0 6.0 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 KXZ45799.1 - 1.3e-21 74.6 0.0 0.002 17.9 0.1 6.3 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 KXZ45799.1 - 3.7e-15 54.6 0.5 0.00054 19.3 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KXZ45799.1 - 1.8e-14 53.3 0.1 0.035 14.0 0.0 5.5 4 2 1 5 5 5 4 EF-hand domain pair DUF4178 PF13785.6 KXZ45799.1 - 0.0011 19.2 0.5 0.31 11.1 0.2 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4178) EF-hand_10 PF14788.6 KXZ45799.1 - 0.0046 16.8 0.2 2.4 8.1 0.0 2.8 2 0 0 2 2 2 2 EF hand Caleosin PF05042.13 KXZ45799.1 - 0.014 15.3 0.0 24 4.8 0.0 3.8 3 1 1 5 5 5 0 Caleosin related protein Dockerin_1 PF00404.18 KXZ45799.1 - 0.032 14.4 0.0 27 5.0 0.0 3.3 4 0 0 4 4 4 0 Dockerin type I domain TFIIA PF03153.13 KXZ45801.1 - 1.8 8.4 12.8 0.14 12.1 1.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Me-amine-dh_L PF02975.14 KXZ45802.1 - 0.13 12.8 0.2 0.34 11.4 0.2 1.7 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Guanylate_cyc PF00211.20 KXZ45803.1 - 9.2e-08 31.9 0.0 1.3e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SelA PF03841.13 KXZ45803.1 - 0.21 10.6 0.1 0.29 10.1 0.1 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase LRR_8 PF13855.6 KXZ45804.1 - 3.5e-08 33.1 23.2 0.0037 17.0 0.2 5.9 5 2 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 KXZ45804.1 - 0.00075 19.8 19.1 0.0023 18.3 3.5 5.6 3 3 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ45804.1 - 0.012 16.1 15.8 65 4.7 0.6 7.6 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 KXZ45804.1 - 8.2 6.8 12.0 8.8 6.7 0.1 5.5 7 0 0 7 7 7 0 Leucine Rich repeat ABC1 PF03109.16 KXZ45805.1 - 5.7e-26 91.0 0.0 1.1e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXZ45805.1 - 2.4e-06 27.7 1.3 2.4e-06 27.7 1.3 4.0 3 1 0 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ45805.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Thioredoxin PF00085.20 KXZ45806.1 - 0.0043 17.0 0.0 0.0055 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AAA PF00004.29 KXZ45807.1 - 3.8e-97 321.8 0.0 5.3e-48 162.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ45807.1 - 6.9e-26 89.8 6.2 2.1e-12 46.6 1.1 3.0 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 KXZ45807.1 - 7.5e-23 80.5 1.2 2.9e-22 78.6 1.2 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KXZ45807.1 - 6.5e-15 55.2 0.0 3.1e-06 27.0 0.0 3.3 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ45807.1 - 7.3e-13 49.3 0.2 0.00018 22.0 0.1 4.0 2 2 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 KXZ45807.1 - 8.7e-13 47.9 0.0 1.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 KXZ45807.1 - 3.2e-12 46.9 0.0 2.6e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXZ45807.1 - 4.8e-12 46.2 0.0 2.2e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXZ45807.1 - 2.6e-10 40.4 0.1 6.7e-05 22.9 0.0 3.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ45807.1 - 4.2e-10 40.0 0.5 0.0083 16.4 0.2 4.8 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 KXZ45807.1 - 1.4e-08 34.3 0.1 0.00079 18.7 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 KXZ45807.1 - 1.9e-08 34.9 0.0 0.0037 17.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KXZ45807.1 - 9.3e-08 32.2 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KXZ45807.1 - 4.9e-07 29.3 0.3 0.03 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXZ45807.1 - 6.8e-07 29.6 0.0 0.0078 16.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 KXZ45807.1 - 8.7e-07 29.1 1.0 0.23 11.3 0.0 3.7 3 1 1 4 4 3 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXZ45807.1 - 2.1e-06 27.6 0.0 0.051 13.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 KXZ45807.1 - 2.7e-06 27.3 0.1 0.00017 21.5 0.0 3.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 KXZ45807.1 - 3.3e-06 27.6 0.0 0.027 15.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 KXZ45807.1 - 4.6e-06 27.0 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KXZ45807.1 - 5.3e-06 26.9 0.4 0.082 13.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KXZ45807.1 - 5.5e-06 26.3 0.0 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 KXZ45807.1 - 5.5e-06 26.4 0.0 0.026 14.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Sigma54_activat PF00158.26 KXZ45807.1 - 6.8e-06 25.9 0.0 0.1 12.3 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 KXZ45807.1 - 7.1e-06 26.0 0.2 0.31 10.9 0.0 3.8 3 1 0 4 4 4 1 NACHT domain Parvo_NS1 PF01057.17 KXZ45807.1 - 9.3e-06 24.9 0.0 0.034 13.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KXZ45807.1 - 1e-05 24.9 0.0 0.042 13.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 KXZ45807.1 - 1.6e-05 24.9 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KXZ45807.1 - 3.8e-05 23.3 0.5 2.6 7.5 0.0 3.7 3 1 0 4 4 3 1 AAA domain AAA_7 PF12775.7 KXZ45807.1 - 3.9e-05 23.3 0.0 0.16 11.5 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KXZ45807.1 - 4.9e-05 23.1 0.2 0.099 12.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 KXZ45807.1 - 8.4e-05 22.0 0.6 3.3 7.0 0.0 3.5 2 1 1 3 3 3 0 KaiC NB-ARC PF00931.22 KXZ45807.1 - 0.00015 21.0 0.0 0.24 10.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.9 KXZ45807.1 - 0.00018 20.8 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 KXZ45807.1 - 0.00068 18.9 0.0 0.39 9.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 KXZ45807.1 - 0.00088 19.1 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KXZ45807.1 - 0.00089 19.3 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 KXZ45807.1 - 0.0014 18.8 0.0 0.98 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 KXZ45807.1 - 0.0022 18.2 0.0 0.7 10.0 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.15 KXZ45807.1 - 0.0023 17.8 0.4 3.2 7.6 0.0 4.0 2 1 0 4 4 4 1 NTPase UFD1 PF03152.14 KXZ45807.1 - 0.0028 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Rad17 PF03215.15 KXZ45807.1 - 0.007 16.3 0.0 1.6 8.6 0.0 2.8 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 KXZ45807.1 - 0.0085 16.4 1.2 6.4 7.1 0.1 3.2 3 1 1 4 4 2 0 AAA domain PhoH PF02562.16 KXZ45807.1 - 0.01 15.3 2.2 2.2 7.7 0.0 2.7 3 0 0 3 3 2 0 PhoH-like protein Zot PF05707.12 KXZ45807.1 - 0.016 14.8 0.0 0.19 11.4 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.22 KXZ45807.1 - 0.018 15.2 0.0 7.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AAA_11 PF13086.6 KXZ45807.1 - 0.021 14.6 0.0 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KXZ45807.1 - 0.025 14.3 0.0 6.4 6.5 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 KXZ45807.1 - 0.028 14.1 0.1 11 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXZ45807.1 - 0.047 13.4 0.0 6.3 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXZ45807.1 - 0.063 13.8 0.3 15 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXZ45807.1 - 0.066 13.0 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IPT PF01745.16 KXZ45807.1 - 0.14 11.5 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase Molydop_binding PF01568.21 KXZ45807.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Hydin_ADK PF17213.3 KXZ45807.1 - 1.9 8.8 4.7 50 4.1 0.0 3.9 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain Sas10 PF09368.10 KXZ45808.1 - 3.5e-26 91.5 4.7 2.2e-25 88.9 5.1 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KXZ45808.1 - 3.7e-20 72.3 0.0 1.4e-19 70.5 0.0 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family TonB_N PF16031.5 KXZ45810.1 - 0.016 15.8 14.9 0.026 15.0 14.9 1.5 1 0 0 1 1 1 0 TonB polyproline region Trypan_PARP PF05887.11 KXZ45810.1 - 0.047 13.7 6.4 0.074 13.0 6.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LPMO_10 PF03067.15 KXZ45811.1 - 1.4e-16 61.7 3.8 6e-16 59.7 3.8 1.7 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ATP-synt_Z PF16594.5 KXZ45811.1 - 0.019 14.5 1.2 0.04 13.4 1.2 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated Peptidase_S49 PF01343.18 KXZ45812.1 - 3.6e-16 59.5 0.0 6.3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 Lipase_3 PF01764.25 KXZ45813.1 - 7.3e-11 42.1 0.0 9.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Ion_trans PF00520.31 KXZ45814.1 - 0.00028 20.2 1.1 0.00043 19.6 1.1 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXZ45814.1 - 0.012 14.3 2.4 0.017 13.9 2.4 1.2 1 0 0 1 1 1 0 Polycystin cation channel OppC_N PF12911.7 KXZ45814.1 - 0.078 13.0 0.2 0.96 9.5 0.2 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C PKD_channel PF08016.12 KXZ45815.1 - 0.035 12.8 1.5 0.044 12.4 1.5 1.1 1 0 0 1 1 1 0 Polycystin cation channel DUF1929 PF09118.11 KXZ45817.1 - 2.8e-23 82.0 0.0 9.3e-23 80.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 KXZ45817.1 - 1.1e-16 60.8 0.1 7.5e-15 54.8 0.1 3.0 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 KXZ45817.1 - 0.00011 22.2 5.2 0.54 10.3 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ45817.1 - 0.0006 20.0 0.1 2.4 8.6 0.0 4.1 2 1 1 3 3 3 1 Kelch motif DUF5122 PF17164.4 KXZ45817.1 - 0.072 13.4 2.4 6.6 7.1 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller DELLA PF12041.8 KXZ45819.1 - 0.059 13.3 0.4 0.37 10.7 0.1 2.5 3 1 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal Nipped-B_C PF12830.7 KXZ45820.1 - 3.5e-22 79.3 0.0 3.6e-21 76.0 0.0 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KXZ45820.1 - 3.9e-07 30.3 0.2 1.7e-06 28.2 0.2 2.2 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KXZ45820.1 - 0.51 10.7 14.3 17 6.0 0.0 6.7 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 KXZ45820.1 - 7.7 7.1 15.2 10 6.8 0.6 4.9 3 0 0 3 3 3 0 HEAT-like repeat PAS PF00989.25 KXZ45821.1 - 7.8e-11 42.0 0.0 0.00019 21.4 0.0 4.8 5 0 0 5 5 5 2 PAS fold PAS_4 PF08448.10 KXZ45821.1 - 1.3e-10 41.5 0.1 0.017 15.4 0.0 5.5 6 0 0 6 6 6 3 PAS fold PAS_9 PF13426.7 KXZ45821.1 - 4.5e-10 39.7 0.0 9.5e-05 22.6 0.0 4.5 4 1 1 5 5 5 2 PAS domain PAS_8 PF13188.7 KXZ45821.1 - 0.00013 21.9 0.1 0.0089 16.0 0.0 3.9 5 0 0 5 5 5 1 PAS domain PAS_3 PF08447.12 KXZ45821.1 - 0.11 12.8 0.0 22 5.4 0.0 2.9 2 0 0 2 2 2 0 PAS fold TPR_17 PF13431.6 KXZ45821.1 - 0.12 12.8 0.1 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KXZ45822.1 - 8.9e-06 25.5 0.1 1.9e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ45822.1 - 0.00014 22.5 6.3 0.00014 22.5 6.3 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1350 PF07082.11 KXZ45823.1 - 2.5e-59 200.6 0.0 1.2e-31 110.0 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1350) Pkinase PF00069.25 KXZ45824.1 - 1.2e-46 159.3 0.0 1.2e-45 155.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45824.1 - 5.8e-22 78.2 0.0 1.1e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ45824.1 - 0.0021 17.4 0.1 0.018 14.4 0.1 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ45824.1 - 0.055 12.2 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXZ45824.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ45824.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_1_2 PF00155.21 KXZ45825.1 - 1.6e-36 126.3 0.0 2e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KXZ45825.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 KXZ45825.1 - 0.082 12.2 0.1 0.18 11.1 0.2 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FAD_binding_7 PF03441.14 KXZ45826.1 - 2.1e-78 262.5 1.1 2.8e-78 262.0 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXZ45826.1 - 1.1e-23 84.0 0.0 2.3e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase WW PF00397.26 KXZ45827.1 - 1.5e-07 31.4 0.1 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 WW domain FliG_M PF14841.6 KXZ45828.1 - 0.089 13.0 0.5 0.85 9.9 0.0 3.0 4 0 0 4 4 4 0 FliG middle domain Methyltransf_11 PF08241.12 KXZ45829.1 - 4.8e-11 43.2 0.0 8.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ45829.1 - 2.7e-06 28.0 0.0 8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ45829.1 - 9.8e-06 25.4 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ45829.1 - 0.00012 21.6 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXZ45829.1 - 0.00023 21.0 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ45829.1 - 0.00046 20.9 0.0 0.00086 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXZ45829.1 - 0.0062 16.4 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase N6_N4_Mtase PF01555.18 KXZ45829.1 - 0.022 14.5 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Methyltransf_29 PF03141.16 KXZ45829.1 - 0.21 10.1 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ion_trans PF00520.31 KXZ45832.1 - 1.3e-14 54.0 12.9 2.8e-14 53.0 12.9 1.6 1 1 0 1 1 1 1 Ion transport protein 4F5 PF04419.14 KXZ45832.1 - 1.5e-09 38.5 4.9 4.3e-09 37.1 4.9 1.8 1 0 0 1 1 1 1 4F5 protein family PKD_channel PF08016.12 KXZ45832.1 - 4.3e-09 35.6 19.9 1.9e-06 26.8 12.4 2.2 1 1 1 2 2 2 2 Polycystin cation channel Sigma70_ner PF04546.13 KXZ45832.1 - 1.5 8.6 5.6 0.95 9.3 0.5 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region Biotin_lipoyl PF00364.22 KXZ45833.1 - 4.9e-08 32.7 0.4 0.0071 16.2 0.1 2.2 1 1 1 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXZ45833.1 - 0.0011 18.7 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like DinB_2 PF12867.7 KXZ45834.1 - 0.48 10.9 12.1 2.8 8.5 0.1 5.0 6 0 0 6 6 6 0 DinB superfamily WD40 PF00400.32 KXZ45835.1 - 7.9e-52 172.1 26.6 2e-08 34.8 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ45835.1 - 5.5e-11 42.6 1.5 0.14 12.4 0.0 4.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ45835.1 - 7.1e-05 21.9 0.7 1.5 7.7 0.0 4.2 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXZ45835.1 - 0.00094 18.6 0.0 0.25 10.6 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 KXZ45835.1 - 0.0016 17.0 0.3 0.11 11.0 0.1 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KXZ45835.1 - 0.0036 16.0 8.2 0.17 10.5 0.1 4.3 2 1 3 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 KXZ45835.1 - 0.16 12.0 0.5 10 6.2 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ribosomal_L16 PF00252.18 KXZ45836.1 - 6.6e-32 110.3 1.5 8.3e-32 110.0 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Adeno_PX PF05829.12 KXZ45836.1 - 0.061 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) NARP1 PF12569.8 KXZ45837.1 - 9.2e-20 71.0 0.8 9.2e-20 71.0 0.8 2.3 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 KXZ45837.1 - 1.1e-11 44.5 7.8 0.03 15.1 0.1 5.8 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ45837.1 - 4.3e-11 42.0 18.9 1.8e-05 24.5 0.4 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45837.1 - 2.6e-10 39.7 14.8 0.00024 21.1 0.2 6.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ45837.1 - 4.6e-10 39.0 11.8 8.3e-07 28.6 0.2 4.4 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.6 KXZ45837.1 - 1.6e-09 38.3 9.1 0.32 11.7 0.8 5.1 4 2 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ45837.1 - 3.6e-08 32.9 11.8 0.00018 21.2 0.9 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ45837.1 - 6.2e-08 32.8 6.0 0.00036 20.7 1.1 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXZ45837.1 - 3.2e-07 30.3 2.3 1.2 9.7 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ45837.1 - 2.3e-06 27.2 5.5 0.003 17.5 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ45837.1 - 2.9e-05 24.5 13.9 0.088 13.3 0.3 4.4 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ45837.1 - 2.9e-05 24.4 6.8 6.1 7.7 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ45837.1 - 3.2e-05 24.0 5.3 0.006 16.7 0.7 4.0 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ45837.1 - 7.3e-05 23.0 13.9 0.1 12.9 0.3 4.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ45837.1 - 0.0022 17.3 4.2 0.079 12.2 0.1 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 KXZ45837.1 - 0.0034 17.8 6.1 0.36 11.3 1.6 3.1 2 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 KXZ45837.1 - 0.0066 16.3 8.3 4.2 7.4 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 KXZ45837.1 - 0.01 15.5 7.2 0.16 11.7 1.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KXZ45837.1 - 0.05 13.7 5.2 15 5.7 0.0 4.4 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 KXZ45837.1 - 0.12 13.0 5.2 44 5.1 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.12 KXZ45837.1 - 0.35 10.9 4.8 6.6 6.8 0.7 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF627) NARP1 PF12569.8 KXZ45838.1 - 6e-65 220.1 1.6 7.1e-65 219.9 1.6 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 KXZ45838.1 - 0.2 11.5 5.5 0.27 11.0 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-N PF05238.13 KXZ45838.1 - 0.21 10.9 1.4 0.29 10.4 1.4 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like RNA_pol_Rpc4 PF05132.14 KXZ45838.1 - 2 8.8 6.0 3 8.3 6.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 SBP PF03110.14 KXZ45840.1 - 1.5e-22 79.7 6.7 2.6e-22 78.9 6.7 1.4 1 0 0 1 1 1 1 SBP domain SOCS PF12610.8 KXZ45840.1 - 7.3 7.1 9.1 0.58 10.6 1.3 2.8 2 1 1 3 3 3 0 Suppressor of cytokine signalling Chloroa_b-bind PF00504.21 KXZ45843.1 - 7.4e-45 153.4 0.0 9.5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Exostosin PF03016.15 KXZ45845.1 - 1e-43 149.7 0.0 1.4e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ45845.1 - 1e-08 35.4 57.5 0.00014 22.1 8.4 4.1 4 1 1 5 5 5 3 EGF-like domain EGF PF00008.27 KXZ45845.1 - 0.00034 20.8 6.6 0.00034 20.8 6.6 3.8 3 0 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 KXZ45845.1 - 0.00082 19.4 30.5 0.0046 17.0 4.5 4.0 3 0 0 3 3 3 2 Tenascin EGF domain CLASP_N PF12348.8 KXZ45846.1 - 4.3e-16 59.2 0.0 1.3e-06 28.1 0.0 3.2 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.22 KXZ45846.1 - 7.5e-07 28.9 3.9 1.2 9.6 0.0 7.1 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 KXZ45846.1 - 0.0041 17.6 9.0 0.81 10.3 0.0 6.3 5 1 1 6 6 6 1 HEAT-like repeat SET PF00856.28 KXZ45847.1 - 1.1e-06 29.2 0.0 9.7e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 SET domain Rrn6 PF10214.9 KXZ45847.1 - 4 5.8 5.9 5.9 5.2 5.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ECH_2 PF16113.5 KXZ45848.1 - 4.1e-103 345.4 0.0 7.8e-67 226.1 0.1 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXZ45848.1 - 2.1e-22 79.6 0.0 3.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_transf_20 PF00982.21 KXZ45849.1 - 3.5e-159 530.5 0.0 4.2e-159 530.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXZ45849.1 - 9e-65 218.1 0.0 8.4e-51 172.3 0.0 2.5 3 0 0 3 3 3 2 Trehalose-phosphatase HTH_17 PF12728.7 KXZ45850.1 - 0.012 15.8 0.1 2.1 8.6 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain PGM_PMM_I PF02878.16 KXZ45851.1 - 3.4e-33 114.3 0.0 5e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXZ45851.1 - 1.4e-28 99.3 0.0 2.7e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXZ45851.1 - 9.4e-15 55.1 0.0 2.3e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KXZ45851.1 - 8.9e-07 29.0 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PurA PF04845.13 KXZ45852.1 - 3.9e-28 98.3 0.2 6.1e-11 42.1 0.1 3.0 2 1 1 3 3 3 3 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 KXZ45852.1 - 0.0044 17.1 0.0 0.083 13.0 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3276) GlgS PF08971.11 KXZ45852.1 - 0.041 13.9 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein CAP PF00188.26 KXZ45853.1 - 3.1e-18 66.8 0.1 4.5e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ANAPC4_WD40 PF12894.7 KXZ45854.1 - 0.0028 17.9 0.0 0.36 11.2 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ45854.1 - 0.013 16.4 6.8 0.16 12.9 0.1 4.9 5 1 0 5 5 5 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXZ45854.1 - 0.025 13.6 0.0 0.089 11.7 0.0 1.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CAP PF00188.26 KXZ45855.1 - 3.1e-18 66.8 0.4 4.1e-18 66.4 0.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAT1 PF09770.9 KXZ45856.1 - 0.039 12.2 0.2 0.087 11.1 0.0 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Inositol_P PF00459.25 KXZ45857.1 - 5.3e-74 249.2 0.2 6.5e-74 248.9 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Cm_res_leader PF08077.11 KXZ45858.1 - 1.1 9.6 3.6 8 7.0 0.6 3.1 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide DUF4189 PF13827.6 KXZ45861.1 - 0.29 11.7 2.5 0.47 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4189) HlyD_D23 PF16576.5 KXZ45862.1 - 0.27 10.4 4.0 0.69 9.1 4.0 1.7 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3592 PF12158.8 KXZ45865.1 - 0.0036 17.4 0.6 0.0057 16.7 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) DUF2362 PF10154.9 KXZ45865.1 - 0.092 11.7 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Cnn_1N PF07989.11 KXZ45865.1 - 0.17 12.1 0.7 0.24 11.6 0.7 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YtxH PF12732.7 KXZ45865.1 - 5.7 7.5 9.5 9 6.9 3.4 2.4 3 0 0 3 3 3 0 YtxH-like protein MaoC_dehydratas PF01575.19 KXZ45866.1 - 4.7e-09 35.9 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain Peptidase_C48 PF02902.19 KXZ45867.1 - 8.3e-33 114.0 0.1 2.5e-32 112.5 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain 2OG-FeII_Oxy_2 PF13532.6 KXZ45868.1 - 4.5e-34 118.3 0.0 7.3e-33 114.4 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RPE65 PF03055.15 KXZ45869.1 - 2.8e-47 162.0 0.0 1.3e-28 100.4 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein PAP_central PF04928.17 KXZ45870.1 - 0.043 12.8 0.1 0.053 12.5 0.1 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain EccE PF11203.8 KXZ45871.1 - 0.083 13.2 6.2 0.11 12.9 6.2 1.3 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Ank_2 PF12796.7 KXZ45872.1 - 1e-14 54.9 1.9 0.00011 22.7 0.2 4.6 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45872.1 - 1.8e-10 41.1 6.6 0.15 12.7 0.0 7.2 5 3 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45872.1 - 6.9e-07 29.1 4.5 3.3 8.6 0.0 7.6 8 1 1 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ45872.1 - 0.0016 18.7 12.6 65 4.0 0.0 7.7 6 3 3 9 9 9 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ45872.1 - 0.11 13.0 2.5 7.6 7.2 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat TilS PF09179.11 KXZ45872.1 - 3.2 8.3 15.0 5.6 7.5 0.2 4.7 4 0 0 4 4 4 0 TilS substrate binding domain AAA_19 PF13245.6 KXZ45874.1 - 0.0041 17.5 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KXZ45874.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KXZ45874.1 - 0.024 15.0 0.0 0.18 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Dam PF05869.11 KXZ45875.1 - 0.053 13.1 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) Chlam_PMP PF02415.17 KXZ45876.1 - 7e-10 38.8 105.3 0.084 13.4 1.3 15.0 14 2 0 14 14 14 13 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 KXZ45876.1 - 5.2e-05 23.2 52.4 1.5 8.7 2.6 3.9 1 1 1 2 2 2 1 Right handed beta helix region TRP PF06011.12 KXZ45877.1 - 2.6e-05 23.1 12.3 0.00012 21.0 12.8 1.9 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel Ank_2 PF12796.7 KXZ45878.1 - 1.7e-55 185.5 15.2 1.5e-17 64.0 1.4 5.2 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45878.1 - 1.4e-46 156.2 12.6 2.4e-10 40.7 0.4 6.4 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45878.1 - 2.5e-45 147.2 5.7 0.00014 22.0 0.0 10.3 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KXZ45878.1 - 6.6e-38 127.5 18.5 3e-06 27.4 0.0 8.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KXZ45878.1 - 1.1e-30 105.3 22.9 2.2e-09 37.4 0.2 7.4 2 1 6 8 8 8 7 Ankyrin repeats (many copies) CUE PF02845.16 KXZ45878.1 - 0.031 14.0 3.7 14 5.5 0.0 4.7 6 0 0 6 6 6 0 CUE domain RVT_2 PF07727.14 KXZ45879.1 - 1.2e-68 231.4 0.0 1.6e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KXZ45879.1 - 4.4e-10 39.8 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KXZ45879.1 - 3.6e-07 29.9 0.0 7.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KXZ45879.1 - 0.00052 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 KXZ45879.1 - 0.0099 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KXZ45880.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PBP1_TM PF14812.6 KXZ45882.1 - 0.082 13.3 4.8 0.23 11.9 4.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CCDC144C PF14915.6 KXZ45884.1 - 0.15 11.2 36.5 0.058 12.5 11.1 4.1 2 2 2 4 4 4 0 CCDC144C protein coiled-coil region Spc7 PF08317.11 KXZ45884.1 - 0.16 10.8 41.6 0.19 10.6 12.7 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.11 KXZ45884.1 - 0.28 11.4 67.5 0.5 10.6 21.5 4.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CREPT PF16566.5 KXZ45884.1 - 1.6 8.9 23.9 0.057 13.6 3.0 3.4 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour PI3K_P85_iSH2 PF16454.5 KXZ45884.1 - 1.8 8.1 18.8 2 8.0 14.3 2.9 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain IFT57 PF10498.9 KXZ45884.1 - 2.3 7.1 14.7 0.36 9.8 1.5 3.1 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 GAS PF13851.6 KXZ45884.1 - 3 7.2 35.1 7.6 5.8 3.5 3.7 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 KXZ45884.1 - 3.7 6.7 11.5 3.5 6.8 0.8 2.7 2 1 1 3 3 3 0 TMPIT-like protein Fez1 PF06818.15 KXZ45884.1 - 9.4 6.6 43.6 2 8.8 4.0 3.3 1 1 1 3 3 3 0 Fez1 Kelch_4 PF13418.6 KXZ45885.1 - 9.1e-21 73.6 0.5 1e-10 41.4 0.1 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KXZ45885.1 - 1.7e-16 59.5 1.0 4.9e-08 32.4 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 KXZ45885.1 - 5.5e-15 55.0 0.2 2.8e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 KXZ45885.1 - 5e-14 52.2 3.5 9.1e-07 29.0 0.1 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KXZ45885.1 - 9.1e-12 44.5 0.9 1.7e-05 24.6 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KXZ45885.1 - 1.9e-10 40.5 0.1 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 2 Kelch motif DUF1668 PF07893.13 KXZ45885.1 - 0.27 10.5 5.5 2.8 7.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) GUN4 PF05419.12 KXZ45886.1 - 9e-51 171.6 0.4 1.1e-50 171.3 0.4 1.1 1 0 0 1 1 1 1 GUN4-like IQ PF00612.27 KXZ45887.1 - 2e-09 36.4 6.7 2.6e-06 26.7 0.8 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif MMR_HSR1 PF01926.23 KXZ45888.1 - 5.1e-17 62.0 0.0 1.3e-14 54.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ45888.1 - 2.4e-06 27.2 0.0 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXZ45888.1 - 0.00019 21.4 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KXZ45888.1 - 0.041 13.5 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4611 PF15387.6 KXZ45888.1 - 0.055 13.7 7.6 0.062 13.5 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AIG1 PF04548.16 KXZ45888.1 - 0.13 11.6 0.1 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 AIG1 family RXT2_N PF08595.11 KXZ45888.1 - 0.14 12.2 0.2 0.32 11.0 0.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Prothymosin PF03247.14 KXZ45888.1 - 8.5 6.9 18.5 1.3 9.5 13.7 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family Sporozoite_P67 PF05642.11 KXZ45888.1 - 8.7 4.3 13.1 1 7.4 0.1 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen bZIP_2 PF07716.15 KXZ45889.1 - 0.00072 19.6 13.1 0.00072 19.6 13.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KXZ45889.1 - 0.001 19.1 12.5 0.0018 18.4 12.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXZ45889.1 - 1.5 9.4 15.9 0.16 12.5 11.5 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor BTB_2 PF02214.22 KXZ45890.1 - 2.8e-09 37.2 0.0 4.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Slx4 PF09494.10 KXZ45890.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Slx4 endonuclease CH_2 PF06294.11 KXZ45891.1 - 8.9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein JHY PF15261.6 KXZ45891.1 - 0.0011 19.7 5.4 0.0011 19.7 5.4 5.2 5 1 0 5 5 5 3 Jhy protein PP2C PF00481.21 KXZ45892.1 - 1e-62 212.1 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXZ45892.1 - 3.5e-08 33.3 1.9 1e-07 31.8 1.9 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DHHA1 PF02272.19 KXZ45892.1 - 0.044 14.2 2.3 0.078 13.4 2.3 1.5 1 0 0 1 1 1 0 DHHA1 domain Met_10 PF02475.16 KXZ45893.1 - 6.5e-41 140.3 0.0 8.7e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Guanylate_cyc PF00211.20 KXZ45896.1 - 1.1e-47 162.1 0.0 1.8e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AUDH_Cupin PF18637.1 KXZ45896.1 - 0.19 11.7 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain Met_10 PF02475.16 KXZ45897.1 - 7.4e-51 172.7 0.0 8.9e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Guanylate_cyc PF00211.20 KXZ45898.1 - 1e-48 165.4 0.0 1.5e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ45899.1 - 4.9e-49 166.4 0.0 7.7e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FTCD_C PF04961.12 KXZ45900.1 - 0.016 15.0 0.8 0.016 15.0 0.8 2.7 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase SlyX PF04102.12 KXZ45900.1 - 0.065 13.9 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 SlyX SelK_SelG PF10961.8 KXZ45900.1 - 0.25 12.0 11.9 3.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Selenoprotein SelK_SelG TRAM_LAG1_CLN8 PF03798.16 KXZ45901.1 - 2.1e-14 53.7 3.7 2.1e-14 53.7 3.7 1.5 1 1 0 1 1 1 1 TLC domain DnaJ PF00226.31 KXZ45902.1 - 1.5e-13 50.7 0.0 3.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Raco_middle PF17651.1 KXZ45902.1 - 0.17 11.6 0.3 0.24 11.1 0.3 1.2 1 0 0 1 1 1 0 RACo middle region Vac14_Fig4_bd PF11916.8 KXZ45904.1 - 1.1e-57 194.5 0.2 7e-50 169.1 0.7 2.3 2 0 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KXZ45904.1 - 5e-16 59.1 0.0 7.5e-13 48.9 0.2 3.8 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KXZ45904.1 - 0.00033 20.7 8.7 0.33 11.3 0.0 5.8 7 0 0 7 7 7 2 HEAT repeat MMS19_C PF12460.8 KXZ45904.1 - 0.00087 18.5 0.3 0.043 12.9 0.1 2.7 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal ParcG PF10274.9 KXZ45904.1 - 0.0033 17.6 0.0 0.052 13.7 0.0 2.3 2 0 0 2 2 2 1 Parkin co-regulated protein HEAT_EZ PF13513.6 KXZ45904.1 - 3.7 8.2 16.6 14 6.3 0.2 5.9 5 1 0 5 5 5 0 HEAT-like repeat Vac14_Fig4_bd PF11916.8 KXZ45906.1 - 1.3e-05 25.0 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Adaptin_N PF01602.20 KXZ45907.1 - 8.5e-87 291.9 7.5 1.1e-86 291.5 7.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KXZ45907.1 - 6e-55 184.7 0.0 1.4e-54 183.5 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KXZ45907.1 - 1.9e-54 183.4 0.0 3.7e-54 182.5 0.0 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 KXZ45907.1 - 8.4e-09 35.7 8.1 1.3e-05 25.3 0.2 3.9 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXZ45907.1 - 1.7e-06 27.8 4.4 0.087 13.1 0.0 5.9 4 1 2 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KXZ45907.1 - 1.9e-06 28.2 11.3 6.5e-05 23.2 0.1 5.1 4 2 1 5 5 5 2 HEAT repeats DUF5578 PF17741.1 KXZ45907.1 - 0.0024 17.3 7.3 0.45 9.9 0.2 4.0 3 1 1 5 5 5 3 Family of unknown function (DUF5578) Prominin PF05478.11 KXZ45907.1 - 0.0042 15.1 0.3 0.0063 14.5 0.3 1.1 1 0 0 1 1 1 1 Prominin Coatomer_g_Cpla PF16381.5 KXZ45907.1 - 0.053 13.6 0.0 0.28 11.3 0.0 2.3 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform Alpha_adaptinC2 PF02883.20 KXZ45907.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Adaptin C-terminal domain AAA_6 PF12774.7 KXZ45909.1 - 9.9e-132 438.8 0.0 3.3e-126 420.7 0.0 3.4 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ45909.1 - 4.5e-100 335.6 4.7 4.5e-100 335.6 4.7 3.7 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KXZ45909.1 - 7.1e-69 231.3 0.3 7.1e-69 231.3 0.3 3.5 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KXZ45909.1 - 1.2e-59 201.8 0.0 6.6e-58 196.1 0.0 3.4 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 KXZ45909.1 - 1.7e-42 144.7 0.0 3e-26 92.0 0.0 6.2 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KXZ45909.1 - 8.9e-37 125.8 0.0 1.8e-35 121.6 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KXZ45909.1 - 2.5e-32 112.2 5.6 2.5e-32 112.2 5.6 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KXZ45909.1 - 6.7e-32 110.6 0.0 4.4e-31 107.9 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 KXZ45909.1 - 9.2e-32 110.0 0.1 1e-26 93.5 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 KXZ45909.1 - 5.3e-30 104.7 0.0 6e-29 101.2 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain DHC_N1 PF08385.12 KXZ45909.1 - 9.4e-29 100.5 1.6 7.8e-28 97.4 0.0 3.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_16 PF13191.6 KXZ45909.1 - 2e-14 54.3 4.8 0.052 13.9 0.0 7.2 6 1 1 7 7 5 4 AAA ATPase domain AAA_22 PF13401.6 KXZ45909.1 - 1e-11 45.2 0.0 0.087 13.1 0.0 5.6 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 KXZ45909.1 - 8.5e-07 29.5 0.1 0.2 12.1 0.0 5.4 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXZ45909.1 - 2.1e-06 27.6 1.2 0.02 14.6 0.0 4.4 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 KXZ45909.1 - 1.3e-05 25.2 0.0 0.12 12.3 0.0 4.3 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KXZ45909.1 - 6.3e-05 22.6 0.0 0.1 12.4 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KXZ45909.1 - 0.00017 21.4 0.1 2.1 8.0 0.0 4.1 4 0 0 4 4 3 1 IstB-like ATP binding protein ABC_tran PF00005.27 KXZ45909.1 - 0.00044 20.8 4.7 0.0085 16.6 0.0 4.7 5 0 0 5 5 3 1 ABC transporter AAA_18 PF13238.6 KXZ45909.1 - 0.00059 20.4 0.0 0.84 10.2 0.0 3.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ45909.1 - 0.00063 20.1 0.0 5.8 7.4 0.0 4.1 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 KXZ45909.1 - 0.00091 19.4 0.1 0.056 13.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXZ45909.1 - 0.0023 17.7 0.0 2.9 7.6 0.0 3.6 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KXZ45909.1 - 0.0039 17.4 0.0 0.21 11.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain ATG16 PF08614.11 KXZ45909.1 - 0.0039 17.4 4.2 0.0039 17.4 4.2 6.2 5 0 0 5 5 4 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KXZ45909.1 - 0.013 15.9 0.4 0.013 15.9 0.4 6.0 6 2 0 6 6 3 0 Fez1 Sigma54_activat PF00158.26 KXZ45909.1 - 0.015 15.0 0.0 0.89 9.2 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 KXZ45909.1 - 0.017 14.9 0.0 0.66 9.7 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 KXZ45909.1 - 0.017 14.8 0.0 0.095 12.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase A1_Propeptide PF07966.12 KXZ45909.1 - 0.017 14.9 1.2 1.8 8.5 0.1 3.1 2 0 0 2 2 2 0 A1 Propeptide T2SSE PF00437.20 KXZ45909.1 - 0.022 13.8 0.0 0.27 10.2 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein CbiA PF01656.23 KXZ45909.1 - 0.024 14.7 0.0 5.5 7.1 0.0 3.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CASP_C PF08172.12 KXZ45909.1 - 0.026 13.9 2.9 0.65 9.3 1.0 3.3 3 0 0 3 3 3 0 CASP C terminal ATPase_2 PF01637.18 KXZ45909.1 - 0.044 13.7 0.0 4.2 7.2 0.0 3.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF3829 PF12889.7 KXZ45909.1 - 0.11 11.9 4.9 3 7.2 0.0 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3829) Catalase-rel PF06628.12 KXZ45909.1 - 0.19 12.0 1.6 2.2 8.5 0.0 3.4 3 0 0 3 3 2 0 Catalase-related immune-responsive Sec20 PF03908.13 KXZ45909.1 - 0.86 9.6 2.7 49 3.9 0.0 4.8 4 0 0 4 4 4 0 Sec20 NYD-SP28_assoc PF14775.6 KXZ45909.1 - 6.7 6.9 6.5 71 3.6 0.2 5.5 5 0 0 5 5 3 0 Sperm tail C-terminal domain Methyltrn_RNA_3 PF02598.17 KXZ45910.1 - 7.2e-08 32.3 0.0 1.5e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methyltransferase tRNA_int_endo PF01974.17 KXZ45911.1 - 1.7e-14 53.6 0.0 2.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Trypsin_2 PF13365.6 KXZ45912.1 - 1.5e-30 107.0 1.9 2.8e-30 106.2 1.9 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KXZ45912.1 - 3.1e-14 53.0 0.1 7.1e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 KXZ45912.1 - 3.6e-08 33.5 0.1 6e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KXZ45912.1 - 3.3e-06 26.8 3.6 0.0065 16.3 0.4 3.3 4 0 0 4 4 4 2 PDZ domain GRASP55_65 PF04495.14 KXZ45912.1 - 0.003 17.9 0.0 0.01 16.2 0.0 1.8 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KXZ45912.1 - 0.089 13.2 0.2 2.6 8.5 0.2 2.8 1 1 0 1 1 1 0 PDZ domain Med25_NR-box PF11244.8 KXZ45912.1 - 0.12 12.8 0.3 0.68 10.4 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing Peptidase_S29 PF02907.15 KXZ45912.1 - 1.4 8.7 4.1 7.3 6.3 1.5 2.3 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Guanylate_cyc PF00211.20 KXZ45914.1 - 1.8e-52 177.6 0.0 3.1e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Myb_CC_LHEQLE PF14379.6 KXZ45914.1 - 0.072 12.8 1.4 0.13 11.9 1.4 1.3 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Guanylate_cyc PF00211.20 KXZ45916.1 - 4.8e-38 130.6 0.0 7.9e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain A_deamin PF02137.18 KXZ45917.1 - 4e-29 102.1 0.0 2.4e-27 96.3 0.0 2.1 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain UCH PF00443.29 KXZ45918.1 - 1.3e-38 132.9 0.0 1.7e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ45918.1 - 1.1e-08 35.1 0.0 1.5e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA_33 PF13671.6 KXZ45919.1 - 2.1e-06 28.0 0.0 3.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ45919.1 - 0.00014 22.3 0.2 0.00035 21.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KXZ45919.1 - 0.0016 18.0 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 KXZ45919.1 - 0.002 18.4 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ45919.1 - 0.008 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ45919.1 - 0.049 13.4 0.4 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXZ45919.1 - 0.059 13.8 0.2 0.13 12.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 KXZ45919.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 KXZ45919.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KXZ45919.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KXZ45919.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin zf-TRAF PF02176.18 KXZ45920.1 - 3e-13 50.2 13.7 6.8e-06 26.7 0.5 3.9 1 1 3 4 4 4 4 TRAF-type zinc finger zf-RING_2 PF13639.6 KXZ45920.1 - 0.0024 18.2 13.1 0.0024 18.2 13.1 2.8 3 0 0 3 3 3 1 Ring finger domain zf-TRAF_2 PF15965.5 KXZ45920.1 - 0.0047 17.4 25.2 0.44 11.0 6.5 3.4 1 1 2 3 3 3 3 TRAF-like zinc-finger zf-RING_6 PF14835.6 KXZ45920.1 - 0.17 11.8 5.1 0.48 10.3 5.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Sina PF03145.16 KXZ45920.1 - 0.23 11.4 11.1 5 7.0 0.3 3.2 2 1 1 3 3 3 0 Seven in absentia protein family zf-C3HC4_2 PF13923.6 KXZ45920.1 - 0.23 11.4 12.4 0.72 9.8 12.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ45920.1 - 6.6 6.7 12.0 20 5.2 12.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyclin_N PF00134.23 KXZ45921.1 - 0.00023 20.9 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain CRS1_YhbY PF01985.21 KXZ45922.1 - 3.8e-14 52.6 0.1 1.7e-13 50.5 0.1 2.1 2 0 0 2 2 2 1 CRS1 / YhbY (CRM) domain DLH PF01738.18 KXZ45922.1 - 0.002 17.7 0.2 0.0069 16.0 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF4050 PF13259.6 KXZ45922.1 - 2.9 8.2 6.2 3e+02 1.6 8.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) GRP PF07172.11 KXZ45922.1 - 6.9 7.4 21.2 20 6.0 21.2 1.8 1 0 0 1 1 1 0 Glycine rich protein family Nucleotid_trans PF03407.16 KXZ45924.1 - 5.6e-44 150.6 0.0 1e-43 149.8 0.0 1.4 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase LRR_4 PF12799.7 KXZ45925.1 - 0.094 13.2 10.4 16 6.1 0.1 6.5 7 1 2 9 9 9 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KXZ45926.1 - 4.5e-08 32.8 0.0 5.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ45926.1 - 9.2e-06 25.7 0.1 0.00035 20.6 0.1 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ45926.1 - 0.057 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cyclin_N PF00134.23 KXZ45927.1 - 1.8e-10 40.6 0.7 2.8e-10 40.0 0.7 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KXZ45927.1 - 0.00021 21.6 0.2 0.0016 18.8 0.0 2.4 2 0 0 2 2 2 1 Cyclin C-terminal domain TFIIB PF00382.19 KXZ45927.1 - 0.051 13.6 0.0 0.051 13.6 0.0 2.9 3 0 0 3 3 3 0 Transcription factor TFIIB repeat PCI PF01399.27 KXZ45928.1 - 1.6e-14 54.3 0.0 6.1e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KXZ45928.1 - 1.1e-11 44.6 0.2 2.4e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain WSC PF01822.19 KXZ45929.1 - 9.8e-36 121.8 14.5 4.1e-15 55.7 1.6 3.5 3 0 0 3 3 3 3 WSC domain Pkinase PF00069.25 KXZ45930.1 - 3.5e-54 184.0 0.0 3.8e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45930.1 - 2.7e-34 118.6 0.0 3.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ45930.1 - 2.4e-06 27.6 0.2 0.015 15.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ45930.1 - 1.2e-05 24.8 1.0 0.00019 20.8 0.1 2.6 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXZ45930.1 - 0.00017 20.5 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ45930.1 - 0.013 14.9 0.5 0.06 12.7 0.5 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ45930.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 KXZ45930.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Ank_2 PF12796.7 KXZ45931.1 - 4.9e-13 49.5 0.0 0.004 17.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45931.1 - 1.5e-06 28.6 2.4 3.8 8.2 0.0 6.4 2 2 5 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45931.1 - 1.5e-05 25.0 0.2 57 4.8 0.0 6.6 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 KXZ45931.1 - 0.14 12.5 3.1 14 6.1 0.0 4.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ45935.1 - 2.3e-05 24.9 0.0 0.014 15.9 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45935.1 - 0.00047 20.7 0.1 3.2 8.4 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45935.1 - 0.11 13.2 0.3 43 5.2 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat MauE PF07291.11 KXZ45936.1 - 0.027 14.2 0.4 0.031 14.1 0.4 1.1 1 0 0 1 1 1 0 Methylamine utilisation protein MauE Pkinase PF00069.25 KXZ45937.1 - 2.2e-18 66.6 0.0 4.4e-17 62.3 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45937.1 - 8.7e-14 51.4 0.2 2.4e-13 50.0 0.1 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ45937.1 - 0.00097 18.5 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ45937.1 - 0.01 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ45937.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ45937.1 - 0.18 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ45937.1 - 0.2 11.2 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 KXZ45938.1 - 2.9e-09 37.4 0.0 0.00045 20.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45938.1 - 4.9e-06 27.0 0.0 1.4 9.5 0.0 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45938.1 - 6.7e-06 26.1 0.0 18 6.3 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Zip PF02535.22 KXZ45940.1 - 1.7e-31 109.7 3.9 5e-28 98.3 0.6 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter rve PF00665.26 KXZ45941.1 - 6.6e-09 36.0 0.0 1.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KXZ45941.1 - 0.034 13.9 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain CBM_20 PF00686.19 KXZ45943.1 - 1.5e-07 31.3 0.0 2.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Filament PF00038.21 KXZ45943.1 - 0.0074 15.9 53.6 0.015 14.9 18.8 3.6 1 1 2 3 3 3 2 Intermediate filament protein Spc7 PF08317.11 KXZ45943.1 - 0.92 8.3 53.6 3 6.6 8.8 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 KXZ45943.1 - 0.92 9.7 53.9 0.04 14.1 11.8 4.2 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KXZ45943.1 - 3.6 7.6 22.0 1.6 8.8 0.7 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 KXZ45943.1 - 4 6.3 31.4 0.7 8.8 2.8 2.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 KXZ45943.1 - 9.2 6.7 49.0 57 4.1 19.0 3.3 1 1 1 2 2 2 0 Fez1 DAGK_cat PF00781.24 KXZ45945.1 - 0.11 12.2 0.4 0.34 10.5 0.4 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain 2OG-FeII_Oxy_2 PF13532.6 KXZ45946.1 - 1.2e-14 55.0 0.0 2.6e-14 53.9 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KXZ45948.1 - 3.1e-10 39.4 0.0 1.3e-05 24.1 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Pirin PF02678.16 KXZ45949.1 - 1.1e-27 96.1 0.0 2.1e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 KXZ45949.1 - 6.4e-11 42.3 0.0 1.5e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 KXZ45949.1 - 4.1e-06 26.4 0.0 1.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Cupin domain GRDP-like PF07173.12 KXZ45949.1 - 8.9e-05 23.2 0.2 0.00022 21.9 0.1 1.6 1 1 0 1 1 1 1 Glycine-rich domain-containing protein-like DUF4224 PF13986.6 KXZ45950.1 - 0.097 12.6 0.1 1.6 8.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4224) Pkinase_Tyr PF07714.17 KXZ45951.1 - 4.7e-06 26.1 0.0 5.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CNOT1_TTP_bind PF16417.5 KXZ45952.1 - 9.6e-59 197.7 0.0 2.7e-58 196.3 0.0 1.7 1 1 1 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KXZ45952.1 - 1.4e-23 83.6 0.0 2.5e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Not1 PF04054.15 KXZ45953.1 - 4.9e-129 430.4 0.0 8.1e-129 429.7 0.0 1.3 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KXZ45953.1 - 6.2e-69 231.8 0.4 9.3e-69 231.2 0.4 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KXZ45953.1 - 3.2e-52 176.3 0.6 5.4e-52 175.6 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Lectin_C PF00059.21 KXZ45954.1 - 0.0023 18.6 10.8 0.73 10.6 0.0 4.7 3 2 2 5 5 5 2 Lectin C-type domain Xlink PF00193.17 KXZ45954.1 - 0.031 14.7 7.3 2.3 8.7 0.7 3.8 3 1 1 4 4 4 0 Extracellular link domain Evr1_Alr PF04777.13 KXZ45955.1 - 3.4e-33 114.1 0.0 8.3e-21 74.3 0.0 2.2 1 1 1 2 2 2 2 Erv1 / Alr family DUF3449 PF11931.8 KXZ45955.1 - 0.64 9.8 1.2 27 4.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Peptidase_S8 PF00082.22 KXZ45957.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Subtilase family DUF2075 PF09848.9 KXZ45958.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KXZ45958.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXZ45958.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KXZ45958.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RHSP PF07999.11 KXZ45958.1 - 0.21 10.4 0.0 0.95 8.2 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon hot spot protein HEAT_2 PF13646.6 KXZ45960.1 - 8.4e-15 54.9 17.3 1.3e-05 25.4 0.1 8.6 6 3 3 9 9 9 5 HEAT repeats HEAT PF02985.22 KXZ45960.1 - 1.4e-09 37.4 34.8 0.00065 19.7 0.1 10.4 12 0 0 12 12 11 3 HEAT repeat RIX1 PF08167.12 KXZ45960.1 - 7.4e-09 35.6 0.0 0.0015 18.3 0.0 5.0 3 3 1 4 4 4 2 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 KXZ45960.1 - 1.2e-08 35.3 54.6 3.2e-05 24.3 0.9 12.2 10 4 5 15 15 12 5 HEAT-like repeat Importin_rep_4 PF18808.1 KXZ45960.1 - 4.2e-08 33.4 7.7 0.00056 20.1 0.1 6.1 6 1 1 7 7 6 2 Importin repeat Vac14_Fab1_bd PF12755.7 KXZ45960.1 - 1.5e-07 31.9 0.2 0.25 12.0 0.0 5.7 4 1 2 6 6 5 1 Vacuolar 14 Fab1-binding region MOR2-PAG1_C PF14225.6 KXZ45960.1 - 2.2e-05 24.4 2.0 0.13 12.1 0.1 4.1 4 0 0 4 4 4 2 Cell morphogenesis C-terminal MMS19_C PF12460.8 KXZ45960.1 - 8.8e-05 21.8 8.6 0.094 11.8 0.2 5.0 5 1 0 5 5 5 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KXZ45960.1 - 0.00081 19.3 0.2 0.13 12.1 0.0 4.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) RTP1_C1 PF10363.9 KXZ45960.1 - 0.00081 19.6 0.0 17 5.7 0.0 4.8 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KXZ45960.1 - 0.0093 15.6 0.1 10 5.6 0.0 4.0 3 1 1 4 4 4 0 CLASP N terminal DUF3730 PF12530.8 KXZ45960.1 - 0.014 14.9 2.8 0.023 14.2 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Cnd1 PF12717.7 KXZ45960.1 - 0.015 15.4 0.9 0.67 10.0 0.0 3.7 4 2 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KXZ45960.1 - 0.025 14.6 10.4 2.7 8.2 0.2 5.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 KXZ45960.1 - 0.025 14.5 2.2 0.58 10.0 0.2 3.7 3 2 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Npa1 PF11707.8 KXZ45960.1 - 0.036 13.4 0.1 0.51 9.6 0.0 2.7 3 1 0 3 3 3 0 Ribosome 60S biogenesis N-terminal V-ATPase_H_N PF03224.14 KXZ45960.1 - 0.042 13.1 0.2 2.1 7.6 0.0 3.1 3 1 0 3 3 3 0 V-ATPase subunit H Spore_III_AB PF09548.10 KXZ45960.1 - 0.082 13.0 0.0 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) IBN_N PF03810.19 KXZ45960.1 - 0.086 12.8 0.0 5 7.1 0.0 3.8 5 0 0 5 5 3 0 Importin-beta N-terminal domain SDA1 PF05285.12 KXZ45961.1 - 0.084 12.3 35.7 0.14 11.6 35.7 1.2 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 KXZ45961.1 - 0.24 11.2 18.7 0.36 10.6 18.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 KXZ45961.1 - 0.4 8.9 41.9 0.54 8.4 41.9 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KXZ45961.1 - 2.2 6.6 34.4 3.3 6.0 34.4 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF5427 PF10310.9 KXZ45961.1 - 2.4 7.0 19.1 7 5.5 14.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Presenilin PF01080.17 KXZ45961.1 - 3 6.5 17.0 4.2 6.0 17.0 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 KXZ45961.1 - 3.7 7.6 6.0 4.2 7.5 4.7 1.7 2 0 0 2 2 2 0 DDHD domain AAA_11 PF13086.6 KXZ45961.1 - 6.5 6.4 10.7 9.9 5.9 10.7 1.2 1 0 0 1 1 1 0 AAA domain BUD22 PF09073.10 KXZ45961.1 - 7.5 5.8 33.1 13 5.0 33.1 1.3 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 KXZ45961.1 - 9.4 5.0 9.6 13 4.5 9.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PRP1_N PF06424.12 KXZ45962.1 - 1.8e-36 125.8 2.3 3.4e-36 124.9 2.3 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KXZ45962.1 - 3e-35 117.9 55.1 0.00028 21.5 0.1 15.3 4 3 11 15 15 15 13 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ45962.1 - 2.1e-19 69.8 29.8 1.4e-05 25.5 0.2 9.7 7 1 3 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ45962.1 - 1.3e-10 41.7 49.6 0.013 16.1 1.1 10.3 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ45962.1 - 6.9e-10 38.6 5.8 1.4 9.5 0.0 9.6 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ45962.1 - 1.5e-06 27.8 22.0 0.064 13.4 0.1 10.1 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ45962.1 - 1.6e-06 27.6 1.1 19 5.0 0.0 7.5 5 2 2 7 7 7 0 TPR repeat Suf PF05843.14 KXZ45962.1 - 4.7e-06 26.8 0.0 3.8 7.4 0.0 4.5 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_6 PF13174.6 KXZ45962.1 - 1.3e-05 25.5 14.2 10 7.0 0.1 10.0 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ45962.1 - 3.5e-05 23.2 27.6 0.035 13.3 0.1 7.1 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ45962.1 - 3.6e-05 23.6 0.1 2.9 8.3 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ45962.1 - 0.00051 19.7 0.0 5.6 7.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat CP12 PF02672.15 KXZ45962.1 - 0.0035 18.0 3.3 0.0058 17.3 0.7 2.8 2 0 0 2 2 1 1 CP12 domain CAF-1_p150 PF11600.8 KXZ45962.1 - 0.013 15.2 3.5 0.029 14.1 3.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NRDE-2 PF08424.10 KXZ45962.1 - 0.016 14.4 11.9 1.8 7.6 0.0 5.6 5 1 1 6 6 6 0 NRDE-2, necessary for RNA interference APG6_N PF17675.1 KXZ45962.1 - 0.028 14.9 0.8 0.028 14.9 0.8 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Hen1_Lam_C PF18441.1 KXZ45962.1 - 0.039 13.8 0.0 12 5.7 0.0 2.7 1 1 1 2 2 2 0 Hen1 La-motif C-terminal domain 7TMR-HDED PF07697.11 KXZ45962.1 - 0.24 11.5 6.0 1.2 9.2 4.4 2.6 1 1 0 1 1 1 0 7TM-HD extracellular Thump_like PF18096.1 KXZ45963.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 THUMP domain-like RRM_1 PF00076.22 KXZ45964.1 - 2.9e-06 27.0 0.0 1.2e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acyltransferase PF01553.21 KXZ45964.1 - 0.0022 17.6 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase RRM_7 PF16367.5 KXZ45964.1 - 0.003 17.6 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif PPP4R2 PF09184.11 KXZ45964.1 - 9 5.8 6.7 15 5.1 6.7 1.2 1 0 0 1 1 1 0 PPP4R2 Rubis-subs-bind PF09273.11 KXZ45965.1 - 0.0049 17.6 0.0 0.14 12.9 0.0 3.1 3 1 0 3 3 3 1 Rubisco LSMT substrate-binding Photo_RC PF00124.19 KXZ45965.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre protein SCP2 PF02036.17 KXZ45967.1 - 2.2e-23 82.7 0.3 2.7e-23 82.4 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KXZ45967.1 - 3.7e-06 27.2 0.0 4.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal FAST_1 PF06743.15 KXZ45968.1 - 0.00018 21.4 0.6 0.0079 16.1 0.1 3.6 5 0 0 5 5 5 1 FAST kinase-like protein, subdomain 1 TPP_enzyme_C PF02775.21 KXZ45968.1 - 0.21 11.3 0.2 1 9.2 0.0 2.2 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3731 PF12531.8 KXZ45968.1 - 0.8 9.5 11.8 0.53 10.1 0.3 4.4 3 2 2 5 5 5 0 DNA-K related protein DUF1601 PF07671.11 KXZ45968.1 - 1.2 9.0 6.0 42 4.1 0.0 4.9 6 0 0 6 6 6 0 Protein of unknown function (DUF1601) SCAI PF12070.8 KXZ45969.1 - 1.7e-70 238.4 0.0 2.3e-68 231.4 0.0 2.2 1 1 0 1 1 1 1 Protein SCAI SHD1 PF03983.12 KXZ45970.1 - 0.0045 16.8 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 2 SLA1 homology domain 1, SHD1 Ank_2 PF12796.7 KXZ45971.1 - 1.5e-33 115.2 2.7 1.4e-17 64.0 0.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45971.1 - 3.6e-31 107.1 0.4 1e-14 54.6 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ45971.1 - 4.6e-30 102.7 7.2 1.8e-07 31.3 0.4 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXZ45971.1 - 2.1e-29 101.2 12.2 2.2e-11 43.8 0.3 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ45971.1 - 8.4e-25 84.1 0.3 3.4e-06 27.0 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat DUF1843 PF08898.10 KXZ45971.1 - 0.44 11.1 5.1 10 6.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF2368 PF10166.9 KXZ45973.1 - 0.091 12.4 2.2 0.14 11.8 2.2 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) PI3K_1B_p101 PF10486.9 KXZ45973.1 - 0.1 10.3 1.9 0.12 10.1 1.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cytochrome-c551 PF10643.9 KXZ45973.1 - 0.15 11.6 1.0 0.19 11.3 1.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 RVT_1 PF00078.27 KXZ45974.1 - 4.8e-08 32.8 0.0 3.3e-07 30.1 0.0 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S8 PF00082.22 KXZ45975.1 - 1.5e-27 96.7 0.3 2.1e-27 96.2 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_M11 PF05548.11 KXZ45977.1 - 1.7e-14 53.7 0.3 1.1e-12 47.7 0.3 2.2 1 1 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 KXZ45977.1 - 0.0073 15.3 0.1 0.014 14.4 0.1 1.5 1 1 0 1 1 1 1 Peptidase M66 Reprolysin_5 PF13688.6 KXZ45977.1 - 0.011 15.9 0.2 0.026 14.7 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXZ45977.1 - 0.03 14.0 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXZ45977.1 - 0.031 14.1 0.0 0.083 12.7 0.0 1.7 2 0 0 2 2 2 0 Matrixin Peptidase_M57 PF12388.8 KXZ45977.1 - 0.053 13.1 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 KXZ45977.1 - 0.055 14.0 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 KXZ45977.1 - 0.071 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M54 PF07998.11 KXZ45977.1 - 0.18 11.8 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin PF01421.19 KXZ45977.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease ABC2_membrane_3 PF12698.7 KXZ45978.1 - 0.0012 18.0 6.9 0.0017 17.5 6.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF596 PF04591.12 KXZ45978.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 GEN1_C PF18380.1 KXZ45979.1 - 4.3 8.3 0.0 4.3 8.3 0.0 3.0 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Pkinase PF00069.25 KXZ45980.1 - 9.5e-56 189.1 0.0 1.1e-27 97.1 0.0 3.4 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ45980.1 - 1.3e-24 86.9 0.0 5.8e-17 61.8 0.0 2.9 1 1 2 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ45980.1 - 5.3e-06 26.0 0.0 0.008 15.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXZ45980.1 - 1.1e-05 24.9 0.0 0.008 15.6 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ45980.1 - 9.4e-05 22.4 3.5 0.62 9.9 3.0 3.1 2 1 0 2 2 2 2 Phosphotransferase enzyme family Ank_2 PF12796.7 KXZ45980.1 - 0.00029 21.3 0.0 0.00079 20.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RIO1 PF01163.22 KXZ45980.1 - 0.001 18.7 0.0 0.37 10.4 0.0 2.9 2 1 1 3 3 3 1 RIO1 family FTA2 PF13095.6 KXZ45980.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.3 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Sacchrp_dh_NADP PF03435.18 KXZ45980.1 - 0.13 12.6 0.9 3 8.1 0.1 3.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Spt20 PF12090.8 KXZ45980.1 - 0.18 11.4 5.8 0.37 10.4 5.8 1.4 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 KXZ45980.1 - 0.28 11.3 9.3 0.61 10.2 9.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 KXZ45981.1 - 7.9e-32 109.7 1.2 1.5e-15 57.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ45981.1 - 2.1e-29 101.5 1.2 5e-11 42.9 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ45981.1 - 5e-24 83.7 1.0 1e-07 32.1 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KXZ45981.1 - 7e-23 78.2 0.0 1.8e-05 24.7 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXZ45981.1 - 4.7e-22 77.8 5.0 2e-06 28.0 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Sulfotransfer_4 PF17784.1 KXZ45981.1 - 0.013 15.3 1.0 1.7 8.5 0.0 2.9 1 1 3 4 4 4 0 Sulfotransferase domain BMC PF00936.19 KXZ45981.1 - 0.019 15.0 1.4 1.9 8.5 0.0 2.6 3 0 0 3 3 3 0 BMC domain Calponin PF00402.18 KXZ45981.1 - 0.027 14.1 4.7 32 4.3 0.0 4.2 5 0 0 5 5 5 0 Calponin family repeat SRCR PF00530.18 KXZ45982.1 - 1.5e-13 51.1 0.9 9.4e-09 35.7 0.0 2.3 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KXZ45983.1 - 3.4e-26 91.7 0.3 1.9e-09 37.9 0.0 3.4 3 1 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ45983.1 - 0.068 13.7 0.4 4.1 8.0 0.2 2.6 3 0 0 3 3 3 0 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KXZ45984.1 - 8e-11 42.3 0.1 1.3e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain VOMI PF03762.17 KXZ45984.1 - 4.6e-07 30.1 0.0 7.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) LPMO_10 PF03067.15 KXZ45986.1 - 8.6e-13 49.4 0.3 1.4e-12 48.7 0.3 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LysM PF01476.20 KXZ45986.1 - 5.1e-12 45.7 0.0 8.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain PAN_4 PF14295.6 KXZ45986.1 - 0.00081 19.2 0.1 0.0027 17.6 0.1 1.9 1 0 0 1 1 1 1 PAN domain RVT_1 PF00078.27 KXZ45987.1 - 1.3e-10 41.1 0.0 2.6e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Terminase_4 PF05119.12 KXZ45987.1 - 0.012 16.0 0.1 0.25 11.8 0.1 2.3 1 1 0 1 1 1 0 Phage terminase, small subunit SRCR PF00530.18 KXZ45988.1 - 2.6e-14 53.5 0.0 3.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain zf-CCHC PF00098.23 KXZ45989.1 - 1.7e-06 27.9 2.1 2.4e-06 27.4 2.1 1.2 1 0 0 1 1 1 1 Zinc knuckle ZapB PF06005.12 KXZ45989.1 - 0.038 14.4 2.6 0.079 13.4 2.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 KXZ45989.1 - 0.07 13.8 0.4 0.12 13.0 0.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA zf-CCHC_2 PF13696.6 KXZ45989.1 - 0.3 11.0 1.2 0.42 10.5 1.2 1.2 1 0 0 1 1 1 0 Zinc knuckle SRCR PF00530.18 KXZ45990.1 - 2.1e-16 60.2 0.1 6.8e-12 45.8 0.0 3.4 3 1 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ45990.1 - 0.026 15.0 0.7 0.91 10.1 0.5 2.3 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain TPIP1 PF15338.6 KXZ45990.1 - 0.063 13.3 0.8 0.27 11.3 1.0 2.0 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 SRCR PF00530.18 KXZ45991.1 - 2.5e-40 137.0 0.1 1.5e-16 60.7 0.2 4.4 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ45991.1 - 0.0031 18.0 1.9 0.75 10.4 0.3 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KXZ45992.1 - 9.4e-68 225.0 6.6 3.5e-18 65.9 0.2 5.7 6 0 0 6 6 6 5 Scavenger receptor cysteine-rich domain VOMI PF03762.17 KXZ45992.1 - 9.1e-09 35.7 0.0 2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) SRCR_2 PF15494.6 KXZ45992.1 - 1.6e-07 31.8 6.4 0.0037 17.8 0.2 4.8 5 0 0 5 5 5 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KXZ45992.1 - 0.0093 16.5 0.2 1.4 9.4 0.0 3.4 4 0 0 4 4 4 1 Hepsin, SRCR domain HYR PF02494.16 KXZ45993.1 - 2.2e-12 47.1 22.5 4.4e-06 26.9 0.9 6.5 7 1 1 8 8 8 3 HYR domain EGF_3 PF12947.7 KXZ45993.1 - 6.3e-06 26.3 78.4 0.04 14.1 5.7 9.9 8 1 1 9 9 9 7 EGF domain EGF PF00008.27 KXZ45993.1 - 1.9 8.9 88.8 0.1 12.9 6.5 9.8 9 0 0 9 9 9 0 EGF-like domain SRCR PF00530.18 KXZ45996.1 - 2.1e-58 195.0 15.5 2.5e-25 88.9 0.9 4.3 3 1 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ45996.1 - 2.3e-10 40.9 5.0 0.0022 18.5 0.3 4.8 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Lectin_C PF00059.21 KXZ45996.1 - 1.5e-05 25.7 0.1 1.5e-05 25.7 0.1 3.5 3 0 0 3 3 3 1 Lectin C-type domain PAN_4 PF14295.6 KXZ45996.1 - 0.0003 20.6 3.1 0.0003 20.6 3.1 3.5 3 0 0 3 3 3 2 PAN domain Hepsin-SRCR PF09272.10 KXZ45996.1 - 0.0016 19.0 0.6 13 6.3 0.0 4.2 3 0 0 3 3 3 2 Hepsin, SRCR domain PAN_3 PF08277.12 KXZ45996.1 - 0.014 15.1 11.0 0.64 9.9 1.5 2.9 2 0 0 2 2 2 0 PAN-like domain Sigma70_r2 PF04542.14 KXZ45996.1 - 0.089 12.6 0.2 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 region 2 PAN_2 PF08276.11 KXZ45996.1 - 1.5 9.0 13.5 2 8.6 1.3 3.5 3 0 0 3 3 3 0 PAN-like domain DUF2318 PF10080.9 KXZ45996.1 - 4.5 7.5 9.5 20 5.4 1.6 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Ephrin_rec_like PF07699.13 KXZ45996.1 - 5.5 6.8 18.0 0.08 12.7 0.8 3.6 3 0 0 3 3 3 0 Putative ephrin-receptor like TRP PF06011.12 KXZ45998.1 - 2.4e-05 23.3 5.3 2.8e-05 23.1 5.3 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel PAN_4 PF14295.6 KXZ46001.1 - 4.2e-07 29.8 10.6 0.005 16.7 2.5 4.1 3 1 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KXZ46001.1 - 0.00099 19.0 1.5 0.00099 19.0 1.5 3.9 3 1 0 3 3 3 2 PAN domain TOC159_MAD PF11886.8 KXZ46001.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain Peptidase_M11 PF05548.11 KXZ46002.1 - 1.5e-11 44.0 1.6 2.6e-11 43.2 0.0 2.1 3 0 0 3 3 3 1 Gametolysin peptidase M11 Gal_Lectin PF02140.18 KXZ46002.1 - 1.5e-07 31.7 0.0 0.0022 18.4 0.0 3.0 3 1 0 3 3 3 2 Galactose binding lectin domain NACHT PF05729.12 KXZ46004.1 - 2.2e-09 37.4 3.7 1e-08 35.3 1.6 2.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXZ46004.1 - 1.8e-08 35.0 0.6 1.1e-07 32.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXZ46004.1 - 3.4e-05 24.3 0.9 0.00033 21.1 0.9 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXZ46004.1 - 0.0002 21.0 0.1 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KXZ46004.1 - 0.00092 18.5 0.9 0.0025 17.1 0.2 1.7 1 1 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.6 KXZ46004.1 - 0.0015 18.8 0.1 0.008 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXZ46004.1 - 0.0074 16.1 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KXZ46004.1 - 0.009 15.7 0.2 0.02 14.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXZ46004.1 - 0.013 15.3 0.1 0.049 13.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2267 PF10025.9 KXZ46004.1 - 0.013 15.7 0.4 0.046 14.0 0.4 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) AAA_28 PF13521.6 KXZ46004.1 - 0.027 14.7 0.1 0.077 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF222 PF02720.17 KXZ46004.1 - 0.029 13.8 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF222) ATPase PF06745.13 KXZ46004.1 - 0.031 13.6 0.1 0.068 12.5 0.1 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 KXZ46004.1 - 0.04 13.1 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KXZ46004.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KXZ46004.1 - 0.075 13.4 0.3 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXZ46004.1 - 0.11 13.0 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 KXZ46005.1 - 1.8e-07 32.0 0.1 2.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXZ46005.1 - 0.00033 20.5 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein UPF0565 PF10561.9 KXZ46005.1 - 0.00067 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 DUF676 PF05057.14 KXZ46005.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KXZ46005.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cutinase PF01083.22 KXZ46005.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Hydrolase_4 PF12146.8 KXZ46005.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Brucella_OMP2 PF05244.11 KXZ46005.1 - 0.05 13.0 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Brucella outer membrane protein 2 Abhydrolase_3 PF07859.13 KXZ46005.1 - 0.065 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Trp_leader2 PF08056.11 KXZ46005.1 - 1.2 9.2 6.1 3.2 7.8 6.1 1.8 1 0 0 1 1 1 0 Tryptophan operon leader peptide BTB PF00651.31 KXZ46008.1 - 0.13 12.5 0.0 1 9.6 0.0 2.3 2 1 0 2 2 2 0 BTB/POZ domain Gal_Lectin PF02140.18 KXZ46009.1 - 8.3e-22 77.4 4.1 2.1e-10 40.9 0.4 2.9 2 0 0 2 2 2 2 Galactose binding lectin domain WSC PF01822.19 KXZ46010.1 - 1.3e-09 38.2 7.8 3.9e-09 36.6 0.3 3.6 3 1 1 4 4 4 2 WSC domain F5_F8_type_C PF00754.25 KXZ46010.1 - 5.2e-06 26.6 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 F5/8 type C domain DUF5000 PF16391.5 KXZ46010.1 - 0.093 12.8 0.0 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function Med6 PF04934.14 KXZ46011.1 - 4.6e-13 49.1 0.1 7.3e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF4407 PF14362.6 KXZ46011.1 - 0.12 11.7 1.2 0.16 11.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arm PF00514.23 KXZ46012.1 - 0.00046 20.1 32.8 0.23 11.6 0.1 8.5 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat Bindin PF02084.15 KXZ46012.1 - 0.016 15.5 0.1 0.016 15.5 0.1 3.1 3 1 0 3 3 3 0 Bindin Ank_2 PF12796.7 KXZ46013.1 - 5.1e-13 49.4 0.4 0.017 15.7 0.0 4.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46013.1 - 8.3e-10 39.0 7.9 0.048 14.3 0.0 7.0 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46013.1 - 1e-09 37.8 2.7 23 6.0 0.0 9.2 10 0 0 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 KXZ46013.1 - 8.5e-05 22.8 3.7 50 4.4 0.0 6.7 6 1 1 7 7 7 0 Ankyrin repeats (many copies) Defensin_4 PF07936.12 KXZ46013.1 - 0.53 10.2 4.1 89 3.1 0.0 4.4 4 0 0 4 4 4 0 Potassium-channel blocking toxin FAD_binding_2 PF00890.24 KXZ46015.1 - 1.2e-45 156.4 16.7 2.4e-45 155.4 16.7 1.5 1 1 0 1 1 1 1 FAD binding domain MTS PF05175.14 KXZ46015.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Ank_2 PF12796.7 KXZ46016.1 - 3.1e-07 30.9 0.1 6.4e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46016.1 - 0.00027 21.4 0.3 0.57 10.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46016.1 - 0.00036 20.8 0.6 7 7.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXZ46016.1 - 0.044 14.1 1.8 4.3 7.8 0.0 3.0 1 1 2 3 3 3 0 Ankyrin repeats (many copies) DUF832 PF05734.11 KXZ46016.1 - 0.062 12.8 0.0 1.1 8.7 0.0 2.3 3 0 0 3 3 3 0 Herpesvirus protein of unknown function (DUF832) Peptidase_S9 PF00326.21 KXZ46018.1 - 0.0014 18.1 5.1 0.0074 15.8 1.5 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family B3 PF02362.21 KXZ46020.1 - 3.7e-08 33.1 0.0 4.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 B3 DNA binding domain BTB PF00651.31 KXZ46021.1 - 0.002 18.3 0.0 0.0041 17.3 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain YceG PF02618.16 KXZ46021.1 - 0.03 13.9 0.0 0.062 12.9 0.0 1.4 2 0 0 2 2 2 0 YceG-like family TRP PF06011.12 KXZ46022.1 - 2.9e-05 23.0 1.2 2.9e-05 23.0 1.2 1.8 3 0 0 3 3 3 1 Transient receptor potential (TRP) ion channel DUF3707 PF12499.8 KXZ46023.1 - 2.4e-49 167.6 18.1 6.7e-27 94.8 6.4 2.0 2 0 0 2 2 2 2 Pherophorin Cyclin_N PF00134.23 KXZ46024.1 - 9.5e-14 51.2 0.5 7.3e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ46024.1 - 0.0075 16.4 2.1 0.34 11.0 1.1 2.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KXZ46025.1 - 3.6e-08 33.2 0.1 3.7e-05 23.5 0.0 3.1 2 1 1 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ46025.1 - 5.5e-05 23.2 0.8 0.0003 20.9 0.7 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KXZ46026.1 - 4.4e-15 55.6 0.0 8.7e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ46026.1 - 0.072 13.2 3.0 0.25 11.4 3.0 1.9 1 0 0 1 1 1 0 Cyclin, C-terminal domain Ank_4 PF13637.6 KXZ46027.1 - 9.1e-19 67.6 5.6 0.007 16.9 0.0 7.9 7 2 1 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ46027.1 - 2.6e-16 59.9 0.0 0.00041 20.9 0.0 4.7 3 3 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ46027.1 - 2.8e-10 39.5 4.3 8.4 7.3 0.1 8.1 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KXZ46027.1 - 6.6e-05 23.1 13.4 3.2 8.2 0.1 7.7 7 2 1 8 8 8 2 Ankyrin repeats (many copies) F-box PF00646.33 KXZ46028.1 - 1.6e-05 24.7 0.1 3.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXZ46028.1 - 1.8e-05 24.5 0.4 4.8e-05 23.2 0.4 1.7 1 0 0 1 1 1 1 F-box-like ubiquitin PF00240.23 KXZ46029.1 - 7.2e-13 48.1 0.0 9.4e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family ubiquitin PF00240.23 KXZ46030.1 - 4.3e-11 42.4 0.0 5.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXZ46030.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain F-box-like PF12937.7 KXZ46032.1 - 3.4e-08 33.2 0.2 7.6e-08 32.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ46032.1 - 0.007 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 KXZ46034.1 - 2.9e-09 37.3 0.5 2.8 8.6 0.0 5.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ46034.1 - 1.3e-08 35.3 0.1 0.011 16.3 0.0 3.4 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_2 PF12796.7 KXZ46035.1 - 3.4e-05 24.4 0.0 5.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46035.1 - 0.011 16.3 0.7 0.24 12.0 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) TPR_2 PF07719.17 KXZ46037.1 - 0.072 13.2 0.2 0.072 13.2 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PBP1_TM PF14812.6 KXZ46038.1 - 0.024 15.0 4.7 0.081 13.3 4.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KXZ46038.1 - 2.4 7.4 4.5 3.8 6.7 4.5 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KXZ46038.1 - 3.1 8.3 6.9 6.7 7.2 6.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ank_4 PF13637.6 KXZ46040.1 - 2e-11 44.2 5.0 0.0012 19.3 0.1 6.7 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ46040.1 - 1.1e-10 42.0 0.3 5.6e-05 23.6 0.0 4.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ46040.1 - 1.5e-05 25.0 1.5 59 4.7 0.0 8.1 9 1 1 10 10 10 0 Ankyrin repeat Ank_5 PF13857.6 KXZ46040.1 - 9.1e-05 22.7 8.0 6.8 7.1 0.1 6.0 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Pkinase PF00069.25 KXZ46041.1 - 1.2e-52 178.9 0.0 1.5e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46041.1 - 2.7e-27 95.7 0.0 3.5e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46041.1 - 6.2e-07 29.0 0.0 8.9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ46041.1 - 0.00045 19.1 0.0 0.00062 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ46041.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXZ46041.1 - 0.017 14.7 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXZ46041.1 - 0.19 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ46042.1 - 2.7e-50 171.2 0.0 3.6e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46042.1 - 1.6e-24 86.6 0.0 2.3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46042.1 - 2.5e-07 30.3 0.0 3.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ46042.1 - 0.00075 18.4 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ46042.1 - 0.0039 17.1 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ46042.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ46043.1 - 6.5e-52 176.5 0.0 1e-51 175.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46043.1 - 1.4e-28 99.9 0.0 2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46043.1 - 8.8e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ46043.1 - 0.0019 17.0 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ46043.1 - 0.0061 16.5 0.2 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lipase_3 PF01764.25 KXZ46044.1 - 1.1e-07 31.9 0.2 2e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF390 PF04094.14 KXZ46046.1 - 1.6 6.9 9.1 1.6 6.9 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) F-box PF00646.33 KXZ46048.1 - 0.00097 19.0 0.1 0.003 17.4 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXZ46048.1 - 0.017 15.0 0.3 0.017 15.0 0.3 2.0 2 0 0 2 2 2 0 F-box-like Ank_4 PF13637.6 KXZ46049.1 - 1.4e-08 35.1 0.1 1.5 9.5 0.0 5.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ46049.1 - 1.2e-06 28.9 0.0 1.1 9.9 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ46049.1 - 0.0008 19.7 0.2 1.6e+02 3.4 0.0 5.8 6 0 0 6 6 6 0 Ankyrin repeat Pkinase PF00069.25 KXZ46050.1 - 1.9e-45 155.3 0.0 2.9e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46050.1 - 1.6e-26 93.1 0.0 2.8e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46050.1 - 0.0034 16.7 0.1 0.032 13.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Acetyltransf_1 PF00583.25 KXZ46051.1 - 1.3e-07 31.8 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ46051.1 - 2.1e-05 24.9 0.0 3.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ46051.1 - 0.00024 21.0 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ46051.1 - 0.0011 19.1 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXZ46051.1 - 0.0041 17.2 0.0 0.045 13.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ46051.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Trypsin PF00089.26 KXZ46052.1 - 5.5e-08 32.9 0.5 0.00028 20.8 1.2 2.2 1 1 1 2 2 2 2 Trypsin zf-CCHC PF00098.23 KXZ46053.1 - 1.9e-23 81.4 23.1 6.5e-09 35.5 1.5 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-GRF PF06839.12 KXZ46053.1 - 6.7e-14 51.7 8.3 2.3e-11 43.6 3.1 2.8 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC_2 PF13696.6 KXZ46053.1 - 6.3e-08 32.3 24.2 0.00054 19.7 2.7 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 KXZ46053.1 - 2.1e-05 24.4 16.0 0.014 15.3 2.1 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_5 PF14787.6 KXZ46053.1 - 0.0022 17.7 18.5 0.11 12.2 1.4 3.7 3 0 0 3 3 3 2 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KXZ46053.1 - 0.01 15.6 11.2 0.99 9.2 0.3 3.2 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.8 KXZ46053.1 - 0.093 13.1 13.6 3.2 8.2 0.8 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DUF3783 PF12646.7 KXZ46054.1 - 4.2e-11 42.6 0.0 9.9e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3783) EF-hand_1 PF00036.32 KXZ46055.1 - 1.1e-13 49.6 2.9 0.0012 18.2 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KXZ46055.1 - 4.8e-13 49.4 0.1 1.7e-07 31.6 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ46055.1 - 7.4e-11 41.1 1.2 0.0028 17.5 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KXZ46055.1 - 7.4e-09 34.7 4.6 0.0031 16.9 0.5 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KXZ46055.1 - 3.9e-08 33.0 3.9 0.0029 17.4 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KXZ46055.1 - 0.00019 21.3 1.2 0.68 9.9 0.0 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand VCBS PF13517.6 KXZ46055.1 - 0.0051 17.4 0.8 4.2 8.0 0.0 3.1 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Pkinase_Tyr PF07714.17 KXZ46056.1 - 1.6e-46 158.7 0.0 2.3e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ46056.1 - 2.6e-41 141.8 0.0 3.9e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KXZ46057.1 - 1.7e-10 41.4 0.0 0.075 13.6 0.0 5.2 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46057.1 - 1.2e-08 35.3 1.5 0.26 11.9 0.0 6.3 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46057.1 - 4e-05 23.7 1.1 61 4.7 0.0 7.5 10 0 0 10 10 10 0 Ankyrin repeat F-box PF00646.33 KXZ46057.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.25 KXZ46058.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KXZ46059.1 - 3.4e-12 46.8 0.3 0.0029 18.1 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46059.1 - 1.8e-09 37.9 11.9 0.083 13.5 1.8 6.7 5 3 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46059.1 - 8.7e-05 22.6 6.8 92 4.1 0.0 8.4 9 1 1 10 10 10 0 Ankyrin repeat Ank_2 PF12796.7 KXZ46060.1 - 6.6e-10 39.4 0.0 2e-05 25.1 0.0 3.7 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46060.1 - 1.6e-09 38.1 4.7 0.16 12.6 0.1 6.4 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46060.1 - 8.1e-05 22.7 1.6 1.5e+02 3.5 0.0 7.3 8 0 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ46060.1 - 0.00048 20.4 1.3 1.9 8.9 0.0 4.5 2 1 2 4 4 4 1 Ankyrin repeats (many copies) FKBP_C PF00254.28 KXZ46062.1 - 3.1e-11 43.4 0.0 6.7e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IFT57 PF10498.9 KXZ46063.1 - 1.1e-106 356.9 0.0 1.2e-106 356.7 0.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 KXZ46063.1 - 0.00018 20.5 8.5 0.0003 19.8 8.5 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.12 KXZ46063.1 - 0.0018 16.5 3.7 0.0027 16.0 3.7 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Mod_r PF07200.13 KXZ46063.1 - 0.002 18.3 8.6 0.016 15.3 5.1 2.4 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein CALCOCO1 PF07888.11 KXZ46063.1 - 0.0027 16.6 10.0 0.0039 16.1 10.0 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ING PF12998.7 KXZ46063.1 - 0.008 16.8 4.2 0.016 15.8 4.2 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Golgin_A5 PF09787.9 KXZ46063.1 - 0.013 15.0 8.9 0.023 14.2 8.4 1.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 KASH_CCD PF14662.6 KXZ46063.1 - 0.014 15.2 3.9 0.014 15.2 3.9 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HAUS6_N PF14661.6 KXZ46063.1 - 0.027 14.1 3.0 16 5.0 0.0 2.3 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Laminin_II PF06009.12 KXZ46063.1 - 0.037 14.1 5.6 0.52 10.3 2.8 2.4 1 1 1 2 2 2 0 Laminin Domain II AAA_13 PF13166.6 KXZ46063.1 - 0.046 12.4 4.0 0.058 12.0 4.0 1.1 1 0 0 1 1 1 0 AAA domain Lebercilin PF15619.6 KXZ46063.1 - 0.048 13.3 14.7 0.086 12.5 14.7 1.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin_2 PF01920.20 KXZ46063.1 - 0.06 13.3 5.7 0.39 10.7 0.5 3.4 2 1 0 3 3 3 0 Prefoldin subunit HrpB2 PF09487.10 KXZ46063.1 - 0.061 13.7 1.1 0.17 12.4 1.1 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Seryl_tRNA_N PF02403.22 KXZ46063.1 - 0.065 13.5 6.5 0.43 10.8 5.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 KXZ46063.1 - 0.095 10.6 0.8 0.19 9.6 0.5 1.4 1 1 0 1 1 1 0 Prominin DUF4763 PF15960.5 KXZ46063.1 - 0.11 11.8 6.7 0.14 11.5 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) TPR_MLP1_2 PF07926.12 KXZ46063.1 - 0.11 12.5 14.1 0.087 12.9 1.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KXZ46063.1 - 0.16 12.0 3.9 1.8 8.6 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CHDCT2 PF08074.11 KXZ46063.1 - 0.16 12.1 3.5 0.27 11.4 3.5 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain FliD_N PF02465.18 KXZ46063.1 - 0.21 12.3 4.3 0.57 10.9 1.6 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FOXP-CC PF16159.5 KXZ46063.1 - 0.34 11.6 1.7 7 7.4 0.1 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain Fmp27_WPPW PF10359.9 KXZ46063.1 - 0.36 9.6 8.8 0.57 9.0 1.6 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Fez1 PF06818.15 KXZ46063.1 - 0.37 11.2 10.0 0.38 11.2 5.8 2.1 1 1 1 2 2 2 0 Fez1 UPF0122 PF04297.14 KXZ46063.1 - 0.43 10.8 2.9 1.6 9.0 2.0 2.1 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Fib_alpha PF08702.10 KXZ46063.1 - 0.61 10.3 4.3 1.2 9.3 4.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KXZ46063.1 - 0.66 9.3 6.6 1 8.6 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALS2CR11 PF15729.5 KXZ46063.1 - 0.66 9.1 4.5 0.97 8.5 4.5 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 TMPIT PF07851.13 KXZ46063.1 - 0.76 9.0 5.0 0.99 8.6 3.4 1.6 1 1 1 2 2 2 0 TMPIT-like protein Sec34 PF04136.15 KXZ46063.1 - 0.85 9.5 7.6 2.5 8.0 1.8 2.7 1 1 1 2 2 2 0 Sec34-like family Jnk-SapK_ap_N PF09744.9 KXZ46063.1 - 0.89 9.8 11.8 2.5 8.3 10.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 KXZ46063.1 - 0.9 8.8 10.4 0.19 11.0 4.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) V-SNARE PF05008.15 KXZ46063.1 - 0.94 9.9 5.1 5.8 7.4 0.6 3.5 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF948 PF06103.11 KXZ46063.1 - 0.95 9.8 3.6 4.4 7.6 0.6 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 KXZ46063.1 - 1 7.2 3.9 0.83 7.5 2.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CLZ PF16526.5 KXZ46063.1 - 1 9.8 8.8 1 9.8 1.0 3.1 1 1 2 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 KXZ46063.1 - 1.2 9.5 5.7 1.9 8.8 3.0 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 KXZ46063.1 - 1.4 8.5 10.7 2.8 7.4 10.7 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.8 KXZ46063.1 - 1.5 8.9 12.8 9.6 6.3 0.3 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 KXZ46063.1 - 1.8 9.1 5.1 3.2 8.3 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 KXZ46063.1 - 3.8 7.6 13.4 2 8.5 9.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sec8_exocyst PF04048.14 KXZ46063.1 - 3.9 7.4 7.3 17 5.3 0.5 3.0 1 1 1 3 3 3 0 Sec8 exocyst complex component specific domain JIP_LZII PF16471.5 KXZ46063.1 - 5.6 7.2 7.8 1.7 8.9 0.5 3.3 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF4200 PF13863.6 KXZ46063.1 - 5.7 7.4 10.6 1.1e+02 3.2 10.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) KxDL PF10241.9 KXZ46063.1 - 6.9 7.0 10.9 0.57 10.5 2.2 3.0 2 2 1 3 3 3 0 Uncharacterized conserved protein APG6_N PF17675.1 KXZ46063.1 - 6.9 7.2 15.1 45 4.6 8.8 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region PIH1 PF08190.12 KXZ46064.1 - 1.1e-30 106.3 0.0 3.7e-30 104.6 0.0 1.7 1 1 0 1 1 1 1 PIH1 N-terminal domain Ank_2 PF12796.7 KXZ46065.1 - 2.8e-12 47.0 0.0 9.1e-05 23.0 0.0 4.3 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46065.1 - 1.3e-10 41.6 8.4 0.05 14.2 0.0 6.9 6 2 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46065.1 - 6.2e-07 29.3 3.3 42 5.2 0.1 9.1 10 0 0 10 10 10 1 Ankyrin repeat Molybdopterin_N PF18364.1 KXZ46065.1 - 0.037 14.0 0.4 1.4 9.0 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain Ank_2 PF12796.7 KXZ46066.1 - 4.4e-08 33.6 3.9 0.042 14.4 0.8 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46066.1 - 3.6e-07 30.6 8.1 1 10.1 0.0 6.9 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46066.1 - 0.00031 21.0 2.5 21 6.1 0.1 6.8 8 0 0 8 8 8 1 Ankyrin repeat Ank_2 PF12796.7 KXZ46067.1 - 2e-09 37.9 0.8 0.43 11.2 0.0 4.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46067.1 - 1.1e-05 25.9 9.4 3 8.5 0.0 6.2 4 3 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46067.1 - 0.0024 18.2 1.8 1.1e+02 3.9 0.1 6.3 7 0 0 7 7 7 0 Ankyrin repeat DUF4224 PF13986.6 KXZ46067.1 - 0.47 10.4 1.9 22 5.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4224) Apt1 PF10351.9 KXZ46068.1 - 0.1 11.5 0.8 0.11 11.3 0.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.12 KXZ46068.1 - 0.55 8.4 19.2 0.0081 14.4 10.4 1.9 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KXZ46068.1 - 0.71 9.2 22.6 0.14 11.5 11.7 2.1 2 0 0 2 2 2 0 BUD22 Gar1 PF04410.14 KXZ46068.1 - 1.2 8.9 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Gar1/Naf1 RNA binding region DNA_pol_phi PF04931.13 KXZ46068.1 - 1.4 6.9 33.9 0.075 11.1 19.6 2.1 2 0 0 2 2 2 0 DNA polymerase phi DUF2722 PF10846.8 KXZ46068.1 - 2.2 7.1 7.3 3.9 6.3 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RNF111_N PF15303.6 KXZ46068.1 - 7.5 6.2 16.8 0.45 10.2 10.2 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Ribosomal_L19e PF01280.20 KXZ46069.1 - 0.19 11.8 0.1 0.3 11.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L19e DUF3446 PF11928.8 KXZ46069.1 - 7.7 6.9 13.5 0.16 12.3 3.7 2.9 3 0 0 3 3 3 0 Early growth response N-terminal domain SATase_N PF06426.14 KXZ46070.1 - 4.5e-38 129.8 0.7 8.1e-38 129.0 0.7 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 KXZ46070.1 - 1.8e-10 40.1 16.2 6.4e-08 32.0 2.5 2.9 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ46070.1 - 2.7e-05 23.8 10.1 7.5e-05 22.4 3.7 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 KXZ46071.1 - 6.8e-39 132.5 0.9 1.3e-38 131.6 0.9 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 KXZ46071.1 - 6.1e-10 38.4 11.8 2.2e-07 30.3 4.4 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ46071.1 - 0.0023 17.6 11.9 0.0033 17.1 5.4 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DIOX_N PF14226.6 KXZ46072.1 - 7.2e-34 117.1 0.0 1.1e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXZ46072.1 - 3e-23 82.2 0.0 5.6e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_6 PF13405.6 KXZ46074.1 - 4.8e-11 41.7 0.0 8.1e-05 22.2 0.4 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KXZ46074.1 - 1.9e-10 41.0 0.0 0.0013 19.2 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KXZ46074.1 - 6.6e-09 34.7 0.0 0.0031 16.9 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KXZ46074.1 - 0.00025 20.8 0.2 2.7 7.9 0.2 3.4 2 2 1 3 3 3 2 EF-hand domain pair DUF4572 PF15139.6 KXZ46074.1 - 0.002 18.1 0.5 0.014 15.4 0.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4572) EF-hand_11 PF08976.11 KXZ46074.1 - 0.03 15.2 0.0 1.3 9.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 KXZ46074.1 - 0.24 11.8 0.8 1.7 9.1 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain Exo_endo_phos PF03372.23 KXZ46075.1 - 1.4e-07 31.3 0.0 2.6e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_6 PF12697.7 KXZ46076.1 - 3.1e-13 50.8 4.0 3.9e-13 50.5 4.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ46076.1 - 3e-09 36.9 0.1 3.6e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ46076.1 - 1.7e-07 30.8 0.0 2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KXZ46076.1 - 0.005 16.7 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 KXZ46076.1 - 0.011 15.4 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 KXZ46076.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family AAA_2 PF07724.14 KXZ46077.1 - 4.1e-50 170.2 0.0 4.2e-48 163.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXZ46077.1 - 7.8e-28 96.5 0.1 2e-27 95.1 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 KXZ46077.1 - 1.7e-20 73.8 0.0 1.1e-09 38.8 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 KXZ46077.1 - 4.6e-18 65.1 1.9 5.9e-09 35.9 0.1 3.2 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KXZ46077.1 - 6.1e-17 61.9 0.1 3.7e-11 43.2 0.0 3.1 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KXZ46077.1 - 7.7e-17 61.1 0.0 2.1e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 KXZ46077.1 - 3.8e-11 43.7 6.3 0.00011 22.6 0.1 4.6 4 1 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 KXZ46077.1 - 8.3e-09 35.8 0.1 0.079 13.2 0.0 4.2 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KXZ46077.1 - 6e-08 32.6 0.1 3.9e-05 23.4 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 KXZ46077.1 - 4.4e-06 26.5 0.2 0.038 13.7 0.0 4.1 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KXZ46077.1 - 7.3e-06 25.8 0.0 0.089 12.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KXZ46077.1 - 3.1e-05 24.5 0.0 0.072 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 KXZ46077.1 - 3.3e-05 23.4 0.0 0.085 12.3 0.0 3.3 2 1 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 KXZ46077.1 - 3.6e-05 23.2 0.3 1.4 8.2 0.0 3.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KXZ46077.1 - 0.00015 21.7 0.0 0.083 12.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 KXZ46077.1 - 0.00038 20.4 0.1 14 5.5 0.0 4.0 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KXZ46077.1 - 0.00045 19.5 0.0 0.045 13.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 KXZ46077.1 - 0.00061 20.1 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KXZ46077.1 - 0.00067 19.7 0.0 0.099 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXZ46077.1 - 0.00074 19.1 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 KXZ46077.1 - 0.0019 18.2 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXZ46077.1 - 0.0034 17.6 0.6 0.65 10.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 KXZ46077.1 - 0.005 17.3 0.0 0.16 12.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 KXZ46077.1 - 0.006 16.4 0.0 3.9 7.4 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXZ46077.1 - 0.0077 15.8 0.0 0.88 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KXZ46077.1 - 0.0087 16.3 0.0 3.5 7.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXZ46077.1 - 0.013 15.4 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ResIII PF04851.15 KXZ46077.1 - 0.021 14.8 0.0 0.28 11.1 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KXZ46077.1 - 0.036 14.3 0.0 11 6.2 0.0 3.5 3 0 0 3 3 2 0 AAA domain AcetylCoA_hydro PF02550.15 KXZ46077.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain DNA_pol3_delta2 PF13177.6 KXZ46077.1 - 0.21 11.4 0.0 6.3 6.6 0.0 2.6 3 0 0 3 3 2 0 DNA polymerase III, delta subunit Ank_2 PF12796.7 KXZ46078.1 - 1.8e-08 34.8 1.0 0.0019 18.7 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46078.1 - 1.9e-05 25.1 8.5 0.64 10.7 0.5 5.6 4 2 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46078.1 - 0.0017 18.7 4.9 60 4.7 0.1 7.2 7 1 1 8 8 8 0 Ankyrin repeat DUF434 PF04256.12 KXZ46078.1 - 0.083 12.6 0.1 7 6.4 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF434) Ank_5 PF13857.6 KXZ46078.1 - 9.4 6.7 8.0 9.7 6.7 1.0 4.2 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KXZ46079.1 - 1e-10 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ46079.1 - 4e-09 36.2 0.0 5.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Spore_III_AF PF09581.10 KXZ46081.1 - 0.079 13.0 0.2 0.1 12.6 0.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Mem_trans PF03547.18 KXZ46081.1 - 0.084 11.2 0.8 0.16 10.3 0.8 1.3 1 0 0 1 1 1 0 Membrane transport protein UPF0565 PF10561.9 KXZ46081.1 - 0.11 11.6 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Hint PF01079.20 KXZ46082.1 - 1.4e-19 70.5 0.0 1.8e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Hint module Pox_Ag35 PF03286.14 KXZ46083.1 - 0.082 12.7 1.4 0.1 12.4 1.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GRP PF07172.11 KXZ46083.1 - 0.18 12.5 10.8 0.35 11.6 10.8 1.6 1 1 0 1 1 1 0 Glycine rich protein family API5 PF05918.11 KXZ46083.1 - 0.48 9.2 2.1 0.54 9.0 2.1 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NOA36 PF06524.12 KXZ46083.1 - 0.52 9.6 4.2 0.6 9.4 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein PTRF_SDPR PF15237.6 KXZ46083.1 - 1 8.9 2.5 1.2 8.7 2.5 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Phospholip_B PF04916.13 KXZ46084.1 - 1.9e-125 419.5 0.0 3e-104 349.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase B JSRP PF15312.6 KXZ46084.1 - 0.055 13.4 0.0 0.25 11.3 0.0 2.2 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein PMSR PF01625.21 KXZ46085.1 - 2.8e-64 215.9 0.5 3.2e-64 215.7 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase YbaB_DNA_bd PF02575.16 KXZ46085.1 - 0.081 13.2 0.0 14 6.0 0.0 2.2 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family BACK PF07707.15 KXZ46086.1 - 8e-05 22.7 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 BTB And C-terminal Kelch BACK PF07707.15 KXZ46087.1 - 7.4e-05 22.8 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank_2 PF12796.7 KXZ46088.1 - 2.1e-10 41.1 1.6 0.012 16.2 0.1 4.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46088.1 - 2.7e-08 34.2 7.8 0.057 14.0 0.0 5.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46088.1 - 4e-05 23.7 5.2 1.8e+02 3.3 0.0 9.4 10 1 1 11 11 11 0 Ankyrin repeat Ank_5 PF13857.6 KXZ46088.1 - 0.039 14.3 4.5 1.3 9.5 0.0 5.1 6 1 1 7 7 7 0 Ankyrin repeats (many copies) DUF434 PF04256.12 KXZ46088.1 - 0.099 12.3 0.1 0.28 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF434) TAP42 PF04177.12 KXZ46089.1 - 3.8e-57 193.8 0.0 4.6e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family TAF4 PF05236.14 KXZ46089.1 - 7.2 6.3 24.0 0.52 10.0 9.4 3.0 2 1 1 3 3 3 0 Transcription initiation factor TFIID component TAF4 family FYDLN_acid PF09538.10 KXZ46089.1 - 7.2 7.3 10.6 10 6.9 5.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) BACK PF07707.15 KXZ46090.1 - 4.5e-05 23.5 0.1 0.0001 22.3 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Pkinase PF00069.25 KXZ46092.1 - 8.2e-30 104.1 0.0 4.1e-13 49.3 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46092.1 - 1.9e-26 92.9 0.0 2.3e-11 43.5 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ46092.1 - 0.00032 19.6 0.2 0.069 11.9 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 KXZ46092.1 - 0.0016 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Ribosomal_60s PF00428.19 KXZ46092.1 - 0.19 12.3 0.0 0.19 12.3 0.0 8.5 7 3 0 7 7 7 0 60s Acidic ribosomal protein peroxidase PF00141.23 KXZ46093.1 - 0.00059 19.6 0.3 0.00087 19.0 0.3 1.3 1 1 0 1 1 1 1 Peroxidase Cu2_monoox_C PF03712.15 KXZ46094.1 - 4.5e-34 117.2 0.0 7.8e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KXZ46094.1 - 7.5e-31 107.1 0.4 1.9e-30 105.8 0.0 1.9 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KXZ46094.1 - 8.1e-13 48.7 0.0 2e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 DOMON domain PP2C_2 PF13672.6 KXZ46094.1 - 4.1 7.0 8.1 2.9 7.5 4.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C Cu2_monoox_C PF03712.15 KXZ46095.1 - 3.9e-32 110.9 0.0 6.4e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KXZ46095.1 - 2.9e-26 92.2 0.0 6.2e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KXZ46095.1 - 3.5e-12 46.6 0.0 4.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 DOMON domain Cu2_monooxygen PF01082.20 KXZ46096.1 - 1.7e-26 93.0 0.1 4e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KXZ46096.1 - 1.2e-25 89.8 0.0 2.3e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 KXZ46096.1 - 1.7e-11 44.4 0.0 5.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 DOMON domain Peptidase_M18 PF02127.15 KXZ46097.1 - 1e-143 479.2 0.0 8.6e-143 476.2 0.0 2.3 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KXZ46097.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase RIIa PF02197.17 KXZ46098.1 - 3.1e-08 33.1 0.0 5.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DNase_II PF03265.15 KXZ46100.1 - 2.5e-48 165.0 0.0 1.1e-29 103.7 0.0 3.5 3 1 0 3 3 3 3 Deoxyribonuclease II Guanylate_cyc PF00211.20 KXZ46101.1 - 1.4e-07 31.4 0.0 8.5e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Sulfotransfer_3 PF13469.6 KXZ46102.1 - 1.3e-08 35.5 0.0 2.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family TPR_1 PF00515.28 KXZ46102.1 - 0.011 15.6 3.1 0.036 13.9 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ46102.1 - 0.021 14.9 1.0 0.021 14.9 1.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ46102.1 - 0.19 12.2 3.7 9.2 6.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sulfotransfer_1 PF00685.27 KXZ46102.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain TPR_4 PF07721.14 KXZ46102.1 - 0.4 11.4 17.3 0.49 11.2 0.6 4.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXZ46102.1 - 1.2 8.8 9.6 5.3 6.7 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 KXZ46102.1 - 2.8 8.3 15.0 0.63 10.4 0.3 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ46102.1 - 3.1 8.0 13.8 4.1 7.6 3.5 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Sulfotransfer_3 PF13469.6 KXZ46103.1 - 6e-20 72.6 0.8 1.5e-19 71.2 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KXZ46103.1 - 0.00038 20.0 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Glyco_hydro_42 PF02449.15 KXZ46104.1 - 2.5e-09 37.0 0.4 2e-05 24.1 0.1 2.1 2 0 0 2 2 2 2 Beta-galactosidase Peptidase_C13 PF01650.18 KXZ46104.1 - 0.16 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase C13 family PAN_4 PF14295.6 KXZ46105.1 - 2.5e-07 30.5 46.1 0.02 14.8 0.2 8.3 8 0 0 8 8 8 7 PAN domain PAN_3 PF08277.12 KXZ46105.1 - 0.00033 20.4 19.1 1.8 8.4 0.1 6.4 6 0 0 6 6 6 3 PAN-like domain MANEC PF07502.14 KXZ46105.1 - 0.78 10.1 20.7 5.1 7.4 0.0 5.9 6 0 0 6 6 6 0 MANEC domain Mito_fiss_reg PF05308.11 KXZ46105.1 - 5.9 6.9 12.7 15 5.6 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator PAN_4 PF14295.6 KXZ46106.1 - 1.4e-13 50.5 38.2 0.014 15.3 0.4 8.8 8 0 0 8 8 8 6 PAN domain PAN_1 PF00024.26 KXZ46106.1 - 1.8e-05 24.6 12.0 0.43 10.6 0.2 5.3 5 0 0 5 5 5 3 PAN domain MANEC PF07502.14 KXZ46106.1 - 0.016 15.5 11.3 1.6 9.1 0.1 4.6 5 0 0 5 5 5 0 MANEC domain TIG PF01833.24 KXZ46107.1 - 4.6e-20 71.5 2.6 5e-08 32.9 0.1 5.4 5 0 0 5 5 5 3 IPT/TIG domain COX6B PF02297.17 KXZ46108.1 - 4.3e-15 55.7 0.1 5.5e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SNRNP27 PF08648.12 KXZ46109.1 - 1.1e-21 76.6 0.1 2.1e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Presenilin PF01080.17 KXZ46109.1 - 1.2 7.8 9.1 1.3 7.8 9.1 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KXZ46109.1 - 9.2 5.0 13.5 11 4.8 13.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 KXZ46110.1 - 9.6e-75 251.3 0.0 1.1e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46110.1 - 4.2e-29 101.6 0.0 5.1e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ46110.1 - 0.0055 16.6 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ46110.1 - 0.0057 15.6 0.0 0.037 13.0 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain ATXN-1_C PF12547.8 KXZ46110.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator Choline_kinase PF01633.20 KXZ46110.1 - 0.041 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KXZ46110.1 - 0.067 12.5 0.2 0.25 10.7 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KXZ46110.1 - 0.072 12.1 0.0 0.35 9.8 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Cyclin_N PF00134.23 KXZ46111.1 - 1.5e-26 92.6 0.0 2.2e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ46111.1 - 3.8e-10 39.9 0.0 6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KXZ46112.1 - 1.3e-26 92.8 0.1 3e-26 91.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ46112.1 - 3.4e-11 43.3 1.2 3.4e-11 43.3 1.2 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain Myc_N PF01056.18 KXZ46112.1 - 0.071 13.0 1.2 0.13 12.1 1.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Utp21 PF04192.12 KXZ46113.1 - 6.9e-37 127.2 0.2 2e-21 76.5 0.0 2.3 3 0 0 3 3 3 2 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KXZ46114.1 - 3.6e-07 30.4 0.0 0.0062 16.8 0.0 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ46114.1 - 6.6e-06 26.8 1.8 0.09 13.7 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Pkinase PF00069.25 KXZ46115.1 - 1.5e-61 208.1 0.0 2.1e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46115.1 - 3.6e-27 95.3 0.0 5.4e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ46115.1 - 0.11 12.4 1.5 0.42 10.5 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family ESSS PF10183.9 KXZ46116.1 - 0.29 11.4 1.9 0.7 10.1 1.9 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RRM_1 PF00076.22 KXZ46117.1 - 5.4e-13 48.6 0.0 9.6e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhlB PF12300.8 KXZ46117.1 - 0.00068 19.8 17.2 0.00068 19.8 17.2 1.8 1 1 1 2 2 2 1 ATP-dependent RNA helicase RhlB Glyoxalase PF00903.25 KXZ46118.1 - 8.8e-11 42.1 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXZ46118.1 - 1.9e-05 24.9 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXZ46118.1 - 0.00019 22.2 0.0 0.00029 21.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KXZ46118.1 - 0.0013 18.9 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KXZ46118.1 - 0.047 13.6 0.0 2.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain BSD PF03909.17 KXZ46119.1 - 5.9e-08 32.6 0.4 1.2e-07 31.6 0.4 1.4 1 0 0 1 1 1 1 BSD domain Pkinase PF00069.25 KXZ46120.1 - 6.6e-44 150.2 0.0 1.9e-41 142.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46120.1 - 2.7e-42 144.9 0.0 7.3e-39 133.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ46120.1 - 0.00078 18.3 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ46120.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family bZIP_1 PF00170.21 KXZ46122.1 - 0.00047 20.2 2.3 0.29 11.2 0.2 2.5 1 1 1 2 2 2 2 bZIP transcription factor DivIC PF04977.15 KXZ46122.1 - 0.017 14.9 1.7 0.08 12.7 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Mod_r PF07200.13 KXZ46122.1 - 0.017 15.2 2.4 0.025 14.7 2.4 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein NUDE_C PF04880.13 KXZ46122.1 - 0.023 15.2 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Prominin PF05478.11 KXZ46122.1 - 0.038 11.9 0.5 0.051 11.5 0.5 1.1 1 0 0 1 1 1 0 Prominin ZapB PF06005.12 KXZ46122.1 - 0.044 14.2 3.8 0.88 10.1 0.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 KXZ46122.1 - 0.047 14.1 0.1 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Zw10 PF06248.13 KXZ46122.1 - 0.055 12.0 0.1 0.068 11.7 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 TPR_MLP1_2 PF07926.12 KXZ46122.1 - 0.073 13.1 2.3 0.12 12.5 2.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXZ46122.1 - 0.087 11.7 1.9 0.12 11.3 1.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KXZ46122.1 - 0.088 13.3 0.8 0.24 11.9 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1690 PF07956.11 KXZ46122.1 - 0.15 12.5 2.9 0.26 11.7 2.9 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2150 PF09920.9 KXZ46122.1 - 0.15 12.0 0.2 0.21 11.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Apolipoprotein PF01442.18 KXZ46122.1 - 0.16 11.8 4.2 0.096 12.5 2.1 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain GIT_CC PF16559.5 KXZ46122.1 - 0.17 11.8 6.3 0.19 11.6 3.2 2.5 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KXZ46122.1 - 0.19 12.4 2.7 0.61 10.7 1.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF2312 PF10073.9 KXZ46122.1 - 0.21 11.3 2.0 6.6 6.5 0.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) HisKA_3 PF07730.13 KXZ46122.1 - 1.2 9.7 4.7 14 6.3 0.2 2.9 3 0 0 3 3 3 0 Histidine kinase HYR PF02494.16 KXZ46123.1 - 8.3e-20 70.9 51.1 3.6e-05 24.0 0.6 9.3 8 1 1 9 9 9 6 HYR domain RicinB_lectin_2 PF14200.6 KXZ46123.1 - 1.3e-05 25.9 0.0 0.0009 19.9 0.0 3.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like EGF_3 PF12947.7 KXZ46123.1 - 0.37 11.0 113.0 0.042 14.0 6.6 12.0 12 0 0 12 12 12 0 EGF domain TACI-CRD2 PF09305.10 KXZ46123.1 - 5 7.2 13.4 5.1 7.2 1.3 4.2 3 0 0 3 3 3 0 TACI, cysteine-rich domain Cyclin_N PF00134.23 KXZ46124.1 - 9.7e-28 96.5 0.0 1.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ46124.1 - 7e-10 39.0 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain DEADboxA PF12343.8 KXZ46124.1 - 0.2 12.2 6.0 0.41 11.2 6.0 1.4 1 0 0 1 1 1 0 Cold shock protein DEAD box A AAR2 PF05282.11 KXZ46125.1 - 1.8e-38 132.8 0.0 3.9e-22 79.1 0.0 3.1 1 1 2 3 3 3 3 AAR2 protein BACK PF07707.15 KXZ46126.1 - 0.0081 16.2 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ46126.1 - 0.0091 16.2 0.0 0.022 15.0 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain DUF2839 PF10999.8 KXZ46127.1 - 0.0088 16.4 0.5 0.015 15.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2839) TRAP_beta PF05753.14 KXZ46128.1 - 1.5e-17 63.6 0.2 1.8e-17 63.3 0.2 1.1 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 KXZ46128.1 - 4.3e-06 27.0 0.4 8.5e-06 26.0 0.4 1.6 1 1 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.11 KXZ46128.1 - 0.013 15.8 0.4 0.023 14.9 0.4 1.7 1 1 0 1 1 1 0 CARDB Phage_T4_gp36 PF03903.13 KXZ46128.1 - 0.099 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Phage T4 tail fibre AI-2E_transport PF01594.16 KXZ46129.1 - 2.1e-32 112.6 26.4 3e-32 112.1 26.4 1.3 1 0 0 1 1 1 1 AI-2E family transporter CIA30 PF08547.12 KXZ46130.1 - 2.5e-40 138.1 0.0 3.6e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.6 KXZ46130.1 - 1.7e-25 90.0 0.8 1.7e-14 54.2 0.0 3.1 2 1 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 KXZ46130.1 - 2.8e-07 30.4 0.4 8e-07 28.8 0.4 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KXZ46130.1 - 0.00042 19.6 0.0 0.055 12.6 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KXZ46130.1 - 0.00044 19.8 0.2 0.00088 18.8 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXZ46130.1 - 0.0022 17.5 0.0 0.0048 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SGBP_B_XBD PF18329.1 KXZ46130.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain HPTransfase PF10090.9 KXZ46130.1 - 0.11 12.3 0.0 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 KXZ46131.1 - 7.8e-19 68.4 0.0 1.1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ46131.1 - 1.1e-05 25.8 0.0 1.7e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Velvet PF11754.8 KXZ46132.1 - 0.063 13.2 7.9 0.29 11.1 4.5 2.1 2 0 0 2 2 2 0 Velvet factor TFIIA PF03153.13 KXZ46132.1 - 0.33 10.9 39.9 0.44 10.5 24.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sulfotransfer_2 PF03567.14 KXZ46133.1 - 0.029 14.3 0.5 0.059 13.3 0.5 1.5 1 0 0 1 1 1 0 Sulfotransferase family MORN PF02493.20 KXZ46135.1 - 1.3e-09 37.4 4.1 0.0022 17.8 1.0 3.7 3 0 0 3 3 3 3 MORN repeat DUF1192 PF06698.11 KXZ46137.1 - 0.96 9.5 6.8 2.3 8.3 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Activator_LAG-3 PF11498.8 KXZ46137.1 - 7.3 5.4 13.3 0.045 12.7 4.9 1.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 cNMP_binding PF00027.29 KXZ46139.1 - 2.6e-12 46.7 0.1 5.4e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KXZ46139.1 - 0.0007 18.9 10.0 0.00091 18.5 10.0 1.1 1 0 0 1 1 1 1 Ion transport protein TPR_16 PF13432.6 KXZ46140.1 - 2.6e-11 44.0 10.5 3e-08 34.2 1.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ46140.1 - 7.7e-11 41.3 2.4 0.0015 18.4 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ46140.1 - 1.4e-09 37.6 0.1 0.0016 18.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ46140.1 - 3.1e-08 33.1 2.0 0.043 13.9 0.1 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ46140.1 - 2.7e-07 30.2 0.1 0.029 14.0 0.0 3.8 2 1 2 4 4 4 2 TPR repeat TPR_10 PF13374.6 KXZ46140.1 - 5.1e-07 29.4 10.3 0.028 14.3 0.2 4.7 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ46140.1 - 3.9e-06 27.2 13.5 0.089 13.7 1.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ46140.1 - 6.6e-06 26.3 7.7 0.00048 20.4 0.4 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ46140.1 - 1.1e-05 25.8 1.4 0.49 11.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ46140.1 - 1.2e-05 25.7 5.6 0.0011 19.5 0.4 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ46140.1 - 1.6e-05 24.9 3.5 0.0012 19.0 0.3 2.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ46140.1 - 6.9e-05 22.5 0.4 0.044 13.6 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 KXZ46140.1 - 0.0001 22.8 5.0 0.00021 21.7 4.9 1.7 1 1 0 1 1 1 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KXZ46140.1 - 0.00032 20.9 0.1 0.1 12.9 0.0 1.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 KXZ46140.1 - 0.0031 17.8 3.5 0.12 12.6 0.8 2.3 1 1 1 2 2 2 2 Tetratrico peptide repeat PvlArgDC PF01862.16 KXZ46140.1 - 0.0049 16.7 0.0 0.006 16.4 0.0 1.1 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) HrpB1_HrpK PF09613.10 KXZ46140.1 - 0.013 15.1 0.3 0.026 14.2 0.2 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 KXZ46140.1 - 0.018 15.3 3.7 0.063 13.6 0.3 2.7 1 1 3 4 4 4 0 Tetratricopeptide repeat DUF4919 PF16266.5 KXZ46140.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_8 PF13181.6 KXZ46140.1 - 0.12 12.6 0.1 7.4 7.1 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXZ46140.1 - 0.17 11.9 0.1 29 4.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ46140.1 - 2.2 9.2 18.7 0.55 11.0 0.6 4.4 5 1 0 5 5 4 0 Tetratricopeptide repeat MIB_HERC2 PF06701.13 KXZ46142.1 - 5.5e-08 32.9 0.6 8.9e-08 32.3 0.6 1.4 1 1 0 1 1 1 1 Mib_herc2 Pkinase PF00069.25 KXZ46145.1 - 4e-05 23.1 0.0 8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CCDC-167 PF15188.6 KXZ46145.1 - 0.46 10.9 13.1 0.96 9.8 13.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 HYR PF02494.16 KXZ46146.1 - 0.0045 17.3 3.7 0.0081 16.5 3.7 1.4 1 0 0 1 1 1 1 HYR domain hEGF PF12661.7 KXZ46146.1 - 0.062 13.9 4.2 0.21 12.3 4.2 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 KXZ46146.1 - 0.095 13.0 6.5 0.32 11.3 6.5 1.9 1 1 0 1 1 1 0 EGF-like domain FXa_inhibition PF14670.6 KXZ46146.1 - 0.1 12.9 5.0 0.22 11.9 5.0 1.7 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site TPP_enzyme_C PF02775.21 KXZ46147.1 - 1.1e-05 25.3 0.0 1.1e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PI3_PI4_kinase PF00454.27 KXZ46150.1 - 6.9e-30 104.7 0.0 4e-27 95.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KXZ46150.1 - 1.1e-15 57.5 0.0 2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Macoilin PF09726.9 KXZ46150.1 - 0.1 11.1 4.7 0.15 10.6 4.7 1.1 1 0 0 1 1 1 0 Macoilin family IFT57 PF10498.9 KXZ46150.1 - 0.73 8.7 8.5 1.1 8.1 8.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.22 KXZ46150.1 - 0.87 9.9 6.2 1.2 9.4 5.0 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF5082 PF16888.5 KXZ46150.1 - 0.91 9.8 1.8 2.9 8.2 1.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Lzipper-MIP1 PF14389.6 KXZ46150.1 - 1.6 9.1 16.3 0.17 12.2 4.0 3.6 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF1127 PF06568.11 KXZ46150.1 - 2.2 8.1 6.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) F-box PF00646.33 KXZ46151.1 - 0.00022 21.0 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXZ46151.1 - 0.00031 20.6 0.1 0.00088 19.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXZ46151.1 - 0.0027 18.1 0.6 1.5 9.3 0.2 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Cupredoxin_1 PF13473.6 KXZ46152.1 - 1.8e-06 28.0 0.0 1.5e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Cupredoxin-like domain DUF167 PF02594.16 KXZ46153.1 - 0.00061 19.9 0.0 0.00094 19.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 PreAtp-grasp PF18604.1 KXZ46153.1 - 0.062 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Pre ATP-grasp domain SbcD_C PF12320.8 KXZ46153.1 - 0.08 13.3 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain LRR_8 PF13855.6 KXZ46154.1 - 7.1e-14 51.3 3.4 1e-07 31.6 4.6 3.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KXZ46154.1 - 1.9e-09 37.6 4.7 0.00035 20.9 3.2 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ46154.1 - 2e-07 30.6 7.3 1.3 9.9 0.7 6.4 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 KXZ46154.1 - 0.0018 18.2 16.2 2.8 8.2 1.7 6.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.6 KXZ46155.1 - 9.1e-29 99.0 34.2 0.00075 19.2 2.7 10.8 9 1 1 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KXZ46155.1 - 3.4e-17 62.2 30.9 0.0045 17.4 0.1 11.4 6 2 7 14 14 14 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ46155.1 - 1.6e-10 40.1 7.7 19 6.3 0.0 11.1 11 1 0 11 11 11 1 Leucine Rich Repeat WSC PF01822.19 KXZ46155.1 - 2e-05 24.7 0.1 3.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 WSC domain LRR_6 PF13516.6 KXZ46155.1 - 0.017 15.1 25.7 5.7 7.3 0.1 10.0 12 0 0 12 12 12 0 Leucine Rich repeat NMT_C PF02799.15 KXZ46157.1 - 3.2e-70 235.9 0.0 4.5e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KXZ46157.1 - 8.9e-68 227.1 0.0 1.4e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NTP_transf_2 PF01909.23 KXZ46157.1 - 0.00049 20.3 0.0 0.00097 19.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Acetyltransf_1 PF00583.25 KXZ46157.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Polbeta PF18765.1 KXZ46157.1 - 0.21 11.7 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase URO-D PF01208.17 KXZ46158.1 - 4.2e-109 364.9 0.0 4.8e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) AAA_6 PF12774.7 KXZ46159.1 - 6.8e-156 518.3 0.0 1.6e-153 510.5 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ46159.1 - 4.2e-135 450.9 0.0 8.7e-135 449.9 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXZ46159.1 - 3.9e-106 354.7 0.0 1.5e-105 352.8 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KXZ46159.1 - 2.2e-104 348.4 0.0 1.7e-103 345.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXZ46159.1 - 3.6e-90 300.9 0.3 8.9e-90 299.6 0.3 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ46159.1 - 2.2e-80 268.5 0.0 1.1e-78 262.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ46159.1 - 1.3e-52 177.9 0.0 3e-52 176.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXZ46159.1 - 2.6e-48 164.8 10.3 4.9e-48 163.9 9.7 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXZ46159.1 - 8.1e-46 155.0 0.0 1.2e-43 148.0 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXZ46159.1 - 1.2e-37 128.8 0.0 3.5e-37 127.4 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KXZ46159.1 - 8.3e-23 80.9 0.0 8e-06 25.9 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KXZ46159.1 - 1.3e-13 51.0 0.0 3.8e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KXZ46159.1 - 7.4e-08 32.9 0.0 0.018 15.5 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ46159.1 - 0.00023 21.6 1.3 0.33 11.3 0.0 4.8 5 0 0 5 5 3 1 AAA ATPase domain T2SSE PF00437.20 KXZ46159.1 - 0.00033 19.8 0.2 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXZ46159.1 - 0.00099 18.9 2.6 0.35 10.6 0.2 2.9 2 0 0 2 2 2 2 AAA domain Spc7 PF08317.11 KXZ46159.1 - 0.0016 17.4 15.1 0.039 12.8 4.5 2.9 2 0 0 2 2 2 2 Spc7 kinetochore protein AAA_22 PF13401.6 KXZ46159.1 - 0.013 15.8 0.0 1 9.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 KXZ46159.1 - 0.014 14.1 1.1 0.12 11.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) RNA_helicase PF00910.22 KXZ46159.1 - 0.025 15.0 0.0 7.4 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KXZ46159.1 - 0.04 14.5 0.0 1.1 9.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXZ46159.1 - 0.066 13.2 0.8 3.1 7.8 0.1 2.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLZ PF16526.5 KXZ46159.1 - 0.085 13.2 1.5 1.1 9.7 1.5 3.0 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sigma54_activat PF00158.26 KXZ46159.1 - 0.1 12.3 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXZ46159.1 - 0.11 12.2 0.0 0.96 9.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 KXZ46159.1 - 0.24 11.7 0.6 6.9 7.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain DegS PF05384.11 KXZ46159.1 - 1.4 8.4 4.7 2 7.9 0.6 2.7 2 0 0 2 2 2 0 Sensor protein DegS ATG16 PF08614.11 KXZ46159.1 - 1.7 8.9 14.9 0.46 10.7 1.8 3.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KXZ46159.1 - 2.3 8.6 8.5 0.39 11.1 0.3 2.7 2 0 0 2 2 2 0 Fez1 Filament PF00038.21 KXZ46159.1 - 2.6 7.5 11.0 2.1 7.9 1.1 3.4 3 0 0 3 3 3 0 Intermediate filament protein GCD14 PF08704.10 KXZ46160.1 - 5.9e-78 262.0 0.0 8.6e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CotH PF08757.11 KXZ46160.1 - 3e-36 125.6 0.0 3e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 CotH kinase protein Methyltransf_31 PF13847.6 KXZ46160.1 - 2.1e-08 34.1 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ46160.1 - 2.1e-05 25.1 0.0 5.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXZ46160.1 - 0.00031 21.7 0.0 0.00078 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ46160.1 - 0.0022 18.7 0.0 0.0049 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXZ46160.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KXZ46160.1 - 0.003 18.2 0.0 0.0094 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain GNAT_C PF18164.1 KXZ46160.1 - 0.11 12.2 0.3 0.27 10.9 0.3 1.6 1 0 0 1 1 1 0 GNAT-like C-terminal domain CCDC14 PF15254.6 KXZ46161.1 - 2.1 6.9 3.8 3.3 6.2 3.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DUF5518 PF17647.1 KXZ46163.1 - 0.0028 17.8 0.2 0.003 17.7 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5518) GRDP-like PF07173.12 KXZ46164.1 - 5.2e-14 53.1 0.0 3.3e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Acetyltransf_2 PF00797.17 KXZ46165.1 - 1.9e-24 86.8 0.0 1.1e-20 74.5 0.0 2.6 2 1 1 3 3 3 2 N-acetyltransferase APH PF01636.23 KXZ46166.1 - 0.78 9.6 9.4 1 9.2 0.0 2.9 3 1 0 3 3 3 0 Phosphotransferase enzyme family Rhomboid PF01694.22 KXZ46167.1 - 1.2e-07 31.9 17.9 4.2e-07 30.1 17.9 2.1 1 1 0 1 1 1 1 Rhomboid family Borrelia_P83 PF05262.11 KXZ46169.1 - 0.74 8.2 16.9 0.84 8.1 16.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF501 PF04417.12 KXZ46169.1 - 1.3 8.9 6.6 1.7 8.4 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) ALMT PF11744.8 KXZ46169.1 - 8.5 5.1 8.1 8.4 5.1 8.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 KXZ46169.1 - 8.7 5.2 9.1 0.32 9.9 0.3 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 KXZ46169.1 - 8.8 6.7 10.4 11 6.4 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Guanylate_cyc PF00211.20 KXZ46170.1 - 3.4e-14 52.9 0.0 5.4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 KXZ46171.1 - 7.9e-09 35.3 0.0 9.5e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46171.1 - 0.00068 19.0 0.0 0.00093 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.19 KXZ46172.1 - 2.5e-35 122.4 0.0 3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF4022 PF13214.6 KXZ46172.1 - 0.19 12.0 0.2 0.36 11.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) Dynamin_M PF01031.20 KXZ46173.1 - 2.3e-58 197.7 0.2 4.3e-58 196.8 0.2 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXZ46173.1 - 8.3e-50 169.1 0.0 3.2e-49 167.2 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KXZ46173.1 - 1.1e-17 64.0 0.2 1.1e-17 64.0 0.2 2.4 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXZ46173.1 - 1.3e-05 25.2 0.0 6.5e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXZ46173.1 - 0.023 14.9 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXZ46173.1 - 0.29 10.8 3.4 1.3 8.7 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain OTU PF02338.19 KXZ46175.1 - 2.7e-17 63.4 0.0 4.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease SEC-C PF02810.15 KXZ46175.1 - 6.3e-07 29.2 13.4 1e-06 28.5 13.4 1.3 1 0 0 1 1 1 1 SEC-C motif Peptidase_C65 PF10275.9 KXZ46175.1 - 0.00012 21.6 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain DPBB_1 PF03330.18 KXZ46176.1 - 3.6e-10 40.0 0.4 8.1e-10 38.9 0.1 1.8 2 0 0 2 2 2 1 Lytic transglycolase DegS PF05384.11 KXZ46177.1 - 0.0092 15.5 3.9 0.0092 15.5 3.9 1.8 2 0 0 2 2 2 1 Sensor protein DegS APG6_N PF17675.1 KXZ46177.1 - 0.16 12.5 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region IFT57 PF10498.9 KXZ46177.1 - 1.3 8.0 8.9 7.4 5.4 6.3 2.2 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Prominin PF05478.11 KXZ46177.1 - 1.4 6.8 4.0 2 6.3 4.0 1.1 1 0 0 1 1 1 0 Prominin YabA PF06156.13 KXZ46177.1 - 1.9 9.1 15.2 0.86 10.3 2.1 2.7 1 1 1 2 2 2 0 Initiation control protein YabA IFP_35_N PF07334.13 KXZ46177.1 - 4.9 7.3 4.8 1.5 9.0 1.0 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc7 PF08317.11 KXZ46177.1 - 5.2 5.8 25.6 4.3 6.1 13.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FUSC_2 PF13515.6 KXZ46178.1 - 0.00013 22.0 8.8 0.00013 22.0 8.8 4.5 3 2 1 4 4 4 1 Fusaric acid resistance protein-like LptF_LptG PF03739.14 KXZ46178.1 - 0.11 11.3 0.1 0.28 10.0 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG ALMT PF11744.8 KXZ46178.1 - 2 7.1 3.9 0.8 8.5 0.9 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter URO-D PF01208.17 KXZ46179.1 - 1.7e-19 70.2 0.0 2.1e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Glyco_hydro_10 PF00331.20 KXZ46180.1 - 5.1e-38 131.0 0.0 7.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 KXZ46180.1 - 6.3e-08 33.0 1.7 0.0012 19.2 0.6 2.5 2 0 0 2 2 2 2 Carbohydrate binding domain AAA_lid_2 PF17863.1 KXZ46181.1 - 7.6e-16 57.7 0.3 2.7e-15 56.0 0.3 2.0 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 KXZ46181.1 - 8.5e-13 48.2 0.8 8.7e-12 44.9 0.8 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 KXZ46181.1 - 8.5e-13 48.9 0.0 2.5e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXZ46181.1 - 3.7e-07 30.5 0.0 9.8e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 KXZ46181.1 - 9.8e-07 28.9 0.0 6.1e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KXZ46181.1 - 5.7e-06 25.6 0.0 0.00012 21.3 0.0 2.8 3 0 0 3 3 3 1 MCM P-loop domain Sigma54_activat PF00158.26 KXZ46181.1 - 0.00029 20.6 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain VWA_3 PF13768.6 KXZ46181.1 - 0.0028 17.6 0.0 0.009 16.0 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain BSP_II PF05432.11 KXZ46181.1 - 0.0029 17.4 1.6 0.0044 16.8 1.6 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) PAXIP1_C PF15364.6 KXZ46181.1 - 0.026 14.8 7.3 0.05 13.9 7.3 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Mg_chelatase_C PF13335.6 KXZ46181.1 - 0.03 15.0 0.8 0.1 13.2 0.8 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal CENP-B_dimeris PF09026.10 KXZ46181.1 - 5.4 7.5 10.7 13 6.2 10.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_lid_2 PF17863.1 KXZ46182.1 - 3e-16 59.0 1.0 3e-16 59.0 1.0 3.3 3 0 0 3 3 2 1 AAA lid domain VWA_2 PF13519.6 KXZ46182.1 - 5.3e-13 49.5 0.0 1.7e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.21 KXZ46182.1 - 7.3e-13 48.4 0.1 9.8e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI VWA PF00092.28 KXZ46182.1 - 2.9e-07 30.9 0.0 5.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 KXZ46182.1 - 1.3e-06 28.4 0.0 8.2e-05 22.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KXZ46182.1 - 4.3e-06 26.0 0.0 3e-05 23.2 0.0 2.3 3 0 0 3 3 3 1 MCM P-loop domain Sigma54_activat PF00158.26 KXZ46182.1 - 0.00045 20.0 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain PAXIP1_C PF15364.6 KXZ46182.1 - 0.0063 16.8 9.3 0.012 15.9 9.3 1.5 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein DUF961 PF06125.11 KXZ46182.1 - 0.048 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) CCDC53 PF10152.9 KXZ46182.1 - 0.14 12.6 6.2 0.23 11.9 6.2 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex AAA_2 PF07724.14 KXZ46182.1 - 0.22 11.6 1.3 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) CDC45 PF02724.14 KXZ46182.1 - 1.3 7.3 4.5 1.7 6.8 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF444 PF04285.12 KXZ46182.1 - 9.5 5.2 15.0 27 3.7 14.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF444) Porin_3 PF01459.22 KXZ46183.1 - 1.4e-40 139.5 7.0 1.6e-40 139.3 7.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin CARDB PF07705.11 KXZ46183.1 - 0.013 15.7 2.9 0.028 14.7 0.3 2.4 3 0 0 3 3 3 0 CARDB Citrate_bind PF16114.5 KXZ46185.1 - 4e-81 270.7 0.1 5.3e-81 270.4 0.1 1.1 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KXZ46185.1 - 5.1e-12 45.8 0.0 2.1e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain BCDHK_Adom3 PF10436.9 KXZ46186.1 - 3.3e-55 186.4 0.0 5e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXZ46186.1 - 6.6e-13 49.1 0.0 1.2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXZ46186.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S8 PF00082.22 KXZ46188.1 - 0.0093 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Adeno_E3 PF06040.11 KXZ46188.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 protein GDPD PF03009.17 KXZ46189.1 - 8.7e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MlrC_C PF07171.12 KXZ46189.1 - 0.056 13.6 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 MlrC C-terminus GDPD PF03009.17 KXZ46190.1 - 2.6e-20 73.2 0.0 8.4e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family eIF-3_zeta PF05091.12 KXZ46191.1 - 5.7e-175 583.2 0.0 6.5e-175 583.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KXZ46191.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 1 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus E1-E2_ATPase PF00122.20 KXZ46192.1 - 6.7e-49 165.9 3.0 1.8e-48 164.5 0.5 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXZ46192.1 - 1.6e-48 164.8 0.5 3.6e-48 163.7 0.5 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KXZ46192.1 - 1.5e-20 72.7 0.5 1.1e-19 69.9 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KXZ46192.1 - 2.2e-20 73.8 5.0 1.7e-19 70.9 5.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ46192.1 - 1.3e-15 57.2 0.0 2.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXZ46192.1 - 1.8e-05 24.6 0.4 0.00016 21.5 1.1 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ46192.1 - 0.015 15.7 0.1 0.063 13.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Radial_spoke PF04712.12 KXZ46194.1 - 3.3e-111 372.6 0.0 1.6e-110 370.4 0.0 1.8 1 1 0 1 1 1 1 Radial spokehead-like protein Radial_spoke PF04712.12 KXZ46195.1 - 2.7e-97 326.8 0.0 2.9e-73 247.5 0.1 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein PHD PF00628.29 KXZ46196.1 - 1.5e-05 24.7 6.1 2.9e-05 23.9 6.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXZ46196.1 - 0.002 17.6 3.2 0.002 17.6 3.2 1.8 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 KXZ46196.1 - 0.0046 17.2 4.4 0.062 13.6 1.9 2.3 2 0 0 2 2 2 1 C1 domain Zn_ribbon_17 PF17120.5 KXZ46196.1 - 0.19 11.4 3.3 0.4 10.3 3.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zinc_ribbon_10 PF10058.9 KXZ46196.1 - 0.75 9.6 5.4 1.1 9.1 1.4 2.3 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-CCHC_5 PF14787.6 KXZ46196.1 - 1 9.1 6.0 2.8 7.7 0.9 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Nop53 PF07767.11 KXZ46196.1 - 1.2 8.5 18.9 1.8 7.8 18.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PhnA_Zn_Ribbon PF08274.12 KXZ46196.1 - 3 7.9 5.7 36 4.4 0.0 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Prok-RING_1 PF14446.6 KXZ46196.1 - 3.3 7.7 12.1 0.19 11.7 4.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 KXZ46196.1 - 3.8 7.2 9.3 6.1 6.5 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 KXZ46196.1 - 4.2 7.4 7.5 1.5 8.8 3.6 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 KXZ46196.1 - 4.6 7.3 7.3 13 5.9 7.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon Nop14 PF04147.12 KXZ46196.1 - 4.7 5.3 15.6 5.3 5.1 15.6 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 KXZ46196.1 - 4.7 7.0 12.0 6.2 6.6 12.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-B_dimeris PF09026.10 KXZ46196.1 - 7.6 7.0 9.1 17 5.9 9.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 KXZ46196.1 - 7.7 4.7 14.5 9.6 4.4 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin PF00085.20 KXZ46198.1 - 1.6e-23 82.7 0.1 2e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ46198.1 - 5.9e-07 29.9 0.1 9.5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KXZ46198.1 - 0.00021 21.0 0.1 0.00031 20.5 0.1 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KXZ46198.1 - 0.00033 20.9 0.0 0.00052 20.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KXZ46198.1 - 0.0011 18.9 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 KXZ46198.1 - 0.015 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_9 PF14595.6 KXZ46198.1 - 0.052 13.3 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KXZ46198.1 - 0.15 12.2 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Ank_2 PF12796.7 KXZ46201.1 - 2.4e-31 108.1 5.5 5.3e-14 52.6 0.0 3.6 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ46201.1 - 1.4e-20 73.1 17.2 7.7e-07 29.3 0.1 6.1 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ46201.1 - 5.4e-20 71.5 1.1 1.7e-06 28.5 0.0 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46201.1 - 1e-18 65.4 9.9 7.3e-05 22.9 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KXZ46201.1 - 7.6e-16 57.8 13.4 0.006 17.0 0.1 6.2 7 0 0 7 7 6 4 Ankyrin repeat zf-C3HC4_3 PF13920.6 KXZ46201.1 - 9.3e-06 25.4 10.4 1.9e-05 24.4 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ46201.1 - 0.00043 20.6 11.5 0.00043 20.6 11.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXZ46201.1 - 0.0019 18.0 9.4 0.0063 16.4 9.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ46201.1 - 0.12 12.2 9.9 0.23 11.4 9.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXZ46201.1 - 1 9.3 11.1 3.4 7.6 11.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ46201.1 - 2 8.5 9.8 0.44 10.6 5.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ46201.1 - 2.3 8.3 12.6 0.51 10.3 9.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Peptidase_S8 PF00082.22 KXZ46202.1 - 1.5e-28 99.9 0.5 3.2e-28 98.9 0.5 1.5 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 KXZ46202.1 - 1.2e-08 34.9 0.3 4.7e-08 32.9 0.3 2.1 1 0 0 1 1 1 1 PA domain Peptidase_S8 PF00082.22 KXZ46203.1 - 4.3e-33 114.9 0.4 9.4e-33 113.7 0.4 1.6 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 KXZ46203.1 - 6e-08 32.6 0.3 7.9e-07 29.0 0.0 2.8 2 0 0 2 2 2 1 PA domain Borrelia_P83 PF05262.11 KXZ46204.1 - 0.12 10.8 11.9 0.14 10.6 11.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CwsA PF10814.8 KXZ46204.1 - 0.35 11.0 4.8 0.73 10.0 4.8 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DUF5401 PF17380.2 KXZ46204.1 - 0.7 7.9 15.6 1.1 7.3 15.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF3391 PF11871.8 KXZ46204.1 - 1.3 9.6 13.5 1.9 9.0 13.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF501 PF04417.12 KXZ46204.1 - 1.7 8.4 7.3 2.6 7.9 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF2058 PF09831.9 KXZ46204.1 - 3.4 7.8 18.3 4.2 7.5 18.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF3138 PF11336.8 KXZ46204.1 - 3.6 6.1 6.9 4.5 5.8 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Motilin_ghrelin PF04644.12 KXZ46204.1 - 6 6.7 10.5 6.3 6.7 0.1 3.2 3 0 0 3 3 3 0 Motilin/ghrelin DUF4407 PF14362.6 KXZ46204.1 - 9.3 5.5 12.2 12 5.2 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S8 PF00082.22 KXZ46205.1 - 6.9e-29 101.0 0.4 5.3e-28 98.2 0.5 2.1 2 0 0 2 2 2 1 Subtilase family PA PF02225.22 KXZ46205.1 - 1.9e-05 24.6 0.7 1.9e-05 24.6 0.7 3.1 3 0 0 3 3 3 1 PA domain zf-C3HC4_3 PF13920.6 KXZ46206.1 - 8.9e-06 25.5 10.7 1.4e-05 24.8 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sas10_Utp3 PF04000.15 KXZ46206.1 - 0.0061 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ribosomal_L22 PF00237.19 KXZ46207.1 - 6.8e-09 35.9 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CDK2AP PF09806.9 KXZ46207.1 - 0.16 12.0 3.4 0.32 11.0 3.4 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CHZ PF09649.10 KXZ46207.1 - 6 6.4 6.7 16 5.0 0.0 2.7 2 0 0 2 2 2 0 Histone chaperone domain CHZ WD40 PF00400.32 KXZ46208.1 - 2.5e-14 53.4 4.8 0.0033 18.2 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ46208.1 - 3.4e-06 27.3 0.0 0.41 11.0 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ46208.1 - 6.1e-05 22.1 0.1 0.39 9.6 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXZ46208.1 - 0.00054 19.4 0.8 4 6.7 0.0 3.4 2 1 1 4 4 4 3 Neuroblastoma-amplified sequence, N terminal FAM199X PF15814.5 KXZ46209.1 - 0.58 9.2 10.0 1.1 8.3 10.0 1.4 1 0 0 1 1 1 0 Protein family FAM199X Ribosomal_L6 PF00347.23 KXZ46210.1 - 0.0011 19.6 0.0 0.0072 17.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L6 La PF05383.17 KXZ46211.1 - 6.2e-20 71.0 0.0 9.3e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXZ46211.1 - 0.03 14.1 0.1 14 5.6 0.1 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DXP_synthase_N PF13292.6 KXZ46212.1 - 7.4e-113 376.3 0.4 1.6e-112 375.2 0.2 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 KXZ46212.1 - 6.5e-39 133.4 0.3 1.3e-38 132.5 0.3 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXZ46212.1 - 2.5e-34 117.8 0.0 6.1e-34 116.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 KXZ46212.1 - 9.6e-07 28.7 1.8 1.1e-05 25.3 1.8 2.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KXZ46212.1 - 1e-05 24.7 0.4 2.2e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 KXZ46212.1 - 0.00031 19.8 0.2 0.0069 15.4 0.0 2.3 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain AAA PF00004.29 KXZ46213.1 - 1.2e-15 58.1 0.0 2.5e-15 57.1 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXZ46213.1 - 2.4e-14 53.4 0.0 2.6e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KXZ46213.1 - 5.9e-09 36.2 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KXZ46213.1 - 9.5e-07 29.2 0.0 0.00065 20.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXZ46213.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXZ46213.1 - 3.6e-06 27.5 1.5 6.5e-05 23.4 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXZ46213.1 - 4.3e-06 26.6 0.0 1.4e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXZ46213.1 - 0.00025 20.5 0.1 0.015 14.7 0.0 2.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KXZ46213.1 - 0.00034 20.5 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXZ46213.1 - 0.00039 20.5 0.0 0.00078 19.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_assoc_2 PF16193.5 KXZ46213.1 - 0.00091 19.5 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 KXZ46213.1 - 0.0014 18.7 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXZ46213.1 - 0.012 15.4 0.0 0.035 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXZ46213.1 - 0.012 15.9 0.3 0.17 12.2 0.0 2.4 2 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KXZ46213.1 - 0.014 15.2 0.0 0.15 11.8 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 KXZ46213.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXZ46213.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXZ46213.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXZ46213.1 - 0.032 13.7 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KXZ46213.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXZ46213.1 - 0.056 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 KXZ46213.1 - 0.067 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXZ46213.1 - 0.078 13.5 0.0 0.33 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 KXZ46213.1 - 0.099 12.4 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 KXZ46213.1 - 0.11 12.0 0.1 0.57 9.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXZ46213.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 KXZ46213.1 - 0.17 11.2 0.0 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DNA_pol3_delta PF06144.13 KXZ46213.1 - 0.22 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF2075 PF09848.9 KXZ46213.1 - 0.22 10.7 0.0 1.3 8.2 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Usp PF00582.26 KXZ46215.1 - 7.6e-09 36.2 5.4 3.4e-08 34.1 5.4 2.2 1 0 0 1 1 1 1 Universal stress protein family ketoacyl-synt PF00109.26 KXZ46216.1 - 4.3e-254 839.0 83.8 7.1e-57 192.9 4.2 7.4 7 0 0 7 7 6 5 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXZ46216.1 - 7.7e-120 397.4 52.4 1.3e-36 126.2 3.9 7.1 6 0 0 6 6 6 4 KR domain Ketoacyl-synt_C PF02801.22 KXZ46216.1 - 1.3e-117 386.5 26.9 1.3e-25 89.7 1.0 6.6 5 0 0 5 5 5 5 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KXZ46216.1 - 6e-110 359.7 15.0 4.9e-14 52.4 0.2 9.8 9 0 0 9 9 9 9 Phosphopantetheine attachment site AMP-binding PF00501.28 KXZ46216.1 - 5.9e-78 262.3 0.3 3e-77 260.0 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme PS-DH PF14765.6 KXZ46216.1 - 2.1e-54 184.8 33.8 1.6e-15 57.2 1.6 6.3 4 3 0 4 4 4 4 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 KXZ46216.1 - 7.9e-34 116.4 7.9 1.6e-12 47.5 0.3 4.7 3 0 0 3 3 3 3 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXZ46216.1 - 9.2e-31 107.6 4.0 2.4e-13 51.3 0.1 4.7 3 0 0 3 3 3 2 Zinc-binding dehydrogenase AMP-binding_C PF13193.6 KXZ46216.1 - 3.9e-18 66.2 1.7 3.9e-18 66.2 1.7 3.1 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain KAsynt_C_assoc PF16197.5 KXZ46216.1 - 1.7e-15 57.5 0.2 0.019 15.4 0.0 5.1 4 0 0 4 4 4 4 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXZ46216.1 - 4.3e-13 49.2 19.6 0.0025 17.2 0.4 6.0 6 0 0 6 6 6 4 Thiolase, N-terminal domain adh_short PF00106.25 KXZ46216.1 - 7.3e-11 41.9 46.0 3.5e-07 29.9 0.8 7.8 7 1 0 7 7 7 5 short chain dehydrogenase ketoacyl-synt PF00109.26 KXZ46217.1 - 1.2e-51 175.7 4.6 1.2e-51 175.7 4.6 3.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.20 KXZ46217.1 - 1.7e-26 93.8 6.4 3e-18 66.8 0.0 3.8 3 1 0 3 3 3 2 Thioesterase domain Ketoacyl-synt_C PF02801.22 KXZ46217.1 - 1.6e-24 86.2 0.5 1.5e-23 83.0 0.5 3.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KXZ46217.1 - 1.6e-21 76.4 0.0 1.5e-09 38.0 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXZ46217.1 - 0.00034 20.0 1.1 0.0015 17.9 1.1 2.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXZ46217.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension PGAP1 PF07819.13 KXZ46217.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KXZ46217.1 - 0.063 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_2 PF12796.7 KXZ46218.1 - 6.5e-16 58.7 0.0 4.4e-06 27.2 0.0 4.8 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46218.1 - 4e-13 49.6 4.9 0.0068 17.0 0.0 6.8 7 1 0 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46218.1 - 6.9e-10 38.3 0.2 2.4 9.0 0.0 8.2 7 1 1 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ46218.1 - 1.4e-07 31.6 5.8 3 8.3 0.0 7.2 7 2 2 9 9 9 2 Ankyrin repeats (many copies) DAGK_cat PF00781.24 KXZ46219.1 - 9.9e-24 83.4 0.1 2.1e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KXZ46219.1 - 0.02 14.1 0.2 0.041 13.1 0.2 1.5 1 0 0 1 1 1 0 ATP-NAD kinase Big_4 PF07532.11 KXZ46219.1 - 0.046 13.5 0.1 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Neur_chan_LBD PF02931.23 KXZ46220.1 - 1.1e-26 93.6 0.0 1.5e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KXZ46220.1 - 7e-09 36.1 0.0 4.1e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region zf-MYND PF01753.18 KXZ46222.1 - 1.4e-10 41.0 3.7 3.2e-10 39.9 3.7 1.6 1 0 0 1 1 1 1 MYND finger DUF525 PF04379.14 KXZ46223.1 - 8e-24 83.7 0.0 1.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 ApaG domain F-box-like PF12937.7 KXZ46223.1 - 8.7e-07 28.7 0.1 6.7e-06 25.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like SMI1_KNR4 PF09346.10 KXZ46223.1 - 3.8e-06 27.3 0.0 6.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) F-box PF00646.33 KXZ46223.1 - 0.0061 16.4 0.7 0.023 14.6 0.2 2.1 2 0 0 2 2 2 1 F-box domain DUF1970 PF09301.10 KXZ46224.1 - 2.1 8.7 4.7 0.5 10.6 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1970) PIGA PF08288.12 KXZ46226.1 - 3.6e-37 126.8 0.0 9.6e-37 125.5 0.0 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KXZ46226.1 - 1.3e-29 103.3 0.3 2.3e-29 102.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KXZ46226.1 - 1.4e-19 70.3 0.0 2.3e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ46226.1 - 3.5e-17 63.1 2.6 5.3e-17 62.5 0.7 2.2 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXZ46226.1 - 6.7e-14 52.6 0.2 6.7e-14 52.6 0.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KXZ46226.1 - 0.0017 18.4 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KXZ46226.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KXZ46226.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.8 1 1 0 1 1 1 0 Starch synthase catalytic domain ubiquitin PF00240.23 KXZ46227.1 - 7.8e-35 118.5 0.4 1.1e-34 118.0 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KXZ46227.1 - 2.6e-29 100.8 10.4 4.1e-29 100.2 10.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KXZ46227.1 - 8.1e-17 60.8 1.7 9.5e-17 60.6 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXZ46227.1 - 1.6e-05 25.2 0.1 6.3e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXZ46227.1 - 0.0032 17.6 0.1 0.0066 16.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KXZ46227.1 - 0.0049 16.8 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXZ46227.1 - 0.0054 17.0 0.1 0.0093 16.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KXZ46227.1 - 0.014 16.0 0.1 0.016 15.7 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXZ46227.1 - 0.014 15.4 1.1 2.8 8.0 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain TipE PF16972.5 KXZ46227.1 - 0.08 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE T3SS_needle_F PF09392.10 KXZ46228.1 - 0.023 14.9 0.0 0.24 11.6 0.0 1.9 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF3067 PF11267.8 KXZ46229.1 - 7.3e-25 87.4 0.0 7.9e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) MFAP1 PF06991.11 KXZ46231.1 - 6.2e-65 219.1 22.9 6.2e-65 219.1 22.9 3.5 1 1 2 3 3 3 1 Microfibril-associated/Pre-mRNA processing FH2 PF02181.23 KXZ46232.1 - 1.7e-29 103.1 0.0 2.6e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF3381 PF11861.8 KXZ46232.1 - 1.3 8.8 4.5 31 4.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) Glycos_transf_2 PF00535.26 KXZ46233.1 - 0.00073 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Methyltransf_24 PF13578.6 KXZ46234.1 - 9.8e-20 71.6 0.1 3.7e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ46234.1 - 0.00028 20.7 0.0 0.0016 18.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ46234.1 - 0.012 16.3 0.0 2.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_3 PF01596.17 KXZ46234.1 - 0.043 13.0 0.0 3.6 6.7 0.1 2.1 2 0 0 2 2 2 0 O-methyltransferase Kinesin PF00225.23 KXZ46235.1 - 1.5e-95 320.0 0.4 2.5e-95 319.2 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ46235.1 - 1.5e-40 138.5 0.0 2.8e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding CH PF00307.31 KXZ46235.1 - 8.5e-09 35.6 0.0 4.2e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain YabA PF06156.13 KXZ46235.1 - 4e-06 27.4 4.1 0.14 12.8 0.0 4.8 3 1 1 4 4 4 1 Initiation control protein YabA DUF1373 PF07117.11 KXZ46235.1 - 0.0058 16.7 6.7 0.012 15.6 6.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1373) Seryl_tRNA_N PF02403.22 KXZ46235.1 - 0.0066 16.7 5.1 0.0066 16.7 5.1 3.3 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 KXZ46235.1 - 0.0096 16.1 0.3 0.27 11.5 0.0 2.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper CDC24 PF06395.11 KXZ46235.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.8 KXZ46235.1 - 0.044 13.6 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 CAMSAP CH domain Exonuc_VII_L PF02601.15 KXZ46235.1 - 0.088 12.4 10.3 0.017 14.7 4.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit MPS2 PF17060.5 KXZ46235.1 - 0.23 10.7 2.2 7.8 5.7 0.1 2.3 2 0 0 2 2 2 0 Monopolar spindle protein 2 MIP-T3_C PF17749.1 KXZ46235.1 - 0.24 11.4 8.1 0.15 12.0 4.4 2.5 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region FlaC_arch PF05377.11 KXZ46235.1 - 0.38 11.2 2.0 45 4.5 1.0 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KXZ46235.1 - 0.57 9.5 16.0 1.2 8.4 10.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lipoprotein_2 PF00921.17 KXZ46235.1 - 0.66 9.5 5.9 0.066 12.8 1.2 1.6 2 0 0 2 2 2 0 Borrelia lipoprotein DUF1640 PF07798.11 KXZ46235.1 - 0.84 9.7 11.1 4.3 7.3 11.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) AMP-binding_C_2 PF14535.6 KXZ46235.1 - 1.1 9.6 3.3 2.2 8.6 0.1 2.7 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain Nnf1 PF03980.14 KXZ46235.1 - 1.4 9.3 21.4 12 6.4 0.3 4.1 3 0 0 3 3 3 0 Nnf1 Baculo_PEP_C PF04513.12 KXZ46235.1 - 1.4 8.9 7.2 6.2 6.9 0.3 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 KXZ46235.1 - 1.5 8.9 18.9 11 6.1 14.9 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1515 PF07439.11 KXZ46235.1 - 2.4 8.2 6.7 3.5 7.7 3.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Macoilin PF09726.9 KXZ46235.1 - 2.4 6.6 19.5 0.64 8.5 7.9 2.4 2 0 0 2 2 2 0 Macoilin family bZIP_1 PF00170.21 KXZ46235.1 - 2.8 8.1 9.4 4 7.6 0.0 3.4 3 1 0 3 3 3 0 bZIP transcription factor SOGA PF11365.8 KXZ46235.1 - 3 9.0 14.6 34 5.7 0.1 3.6 2 1 0 2 2 2 0 Protein SOGA CCDC144C PF14915.6 KXZ46235.1 - 3.8 6.5 19.0 1.4 8.0 13.8 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Rx_N PF18052.1 KXZ46235.1 - 8.3 6.8 8.1 21 5.5 7.4 2.1 1 1 0 1 1 1 0 Rx N-terminal domain Exostosin PF03016.15 KXZ46236.1 - 1.9e-32 112.7 0.0 1e-16 61.0 0.0 2.1 1 1 1 2 2 2 2 Exostosin family EGF_2 PF07974.13 KXZ46236.1 - 0.00085 19.6 14.2 0.0034 17.7 14.2 2.1 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 KXZ46236.1 - 0.074 13.1 7.0 0.21 11.7 7.0 1.8 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 KXZ46236.1 - 0.2 12.0 8.8 1 9.7 8.8 2.3 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 KXZ46236.1 - 0.66 10.2 7.0 1.8 8.8 7.0 1.7 1 0 0 1 1 1 0 Laminin EGF domain ABC_tran PF00005.27 KXZ46237.1 - 1.9e-10 41.4 0.0 8.5e-10 39.3 0.0 2.1 2 1 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 KXZ46237.1 - 4.5e-07 29.5 6.1 7.8e-07 28.7 6.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KXZ46237.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Spt20 PF12090.8 KXZ46237.1 - 0.31 10.6 8.8 0.49 10.0 8.8 1.2 1 0 0 1 1 1 0 Spt20 family KELK PF15796.5 KXZ46238.1 - 0.24 11.9 1.1 0.44 11.0 1.1 1.3 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Cnn_1N PF07989.11 KXZ46238.1 - 0.35 11.1 0.6 0.68 10.1 0.6 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Mur_ligase_M PF08245.12 KXZ46240.1 - 1.7e-06 28.1 0.0 4.7e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain UPF0146 PF03686.13 KXZ46240.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) FYRC PF05965.14 KXZ46241.1 - 1.6e-18 66.6 0.0 1.2e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 KXZ46241.1 - 2.6e-08 33.6 0.0 4.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus U-box PF04564.15 KXZ46241.1 - 9.7e-05 22.5 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 U-box domain CUE PF02845.16 KXZ46241.1 - 0.051 13.3 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 CUE domain UBA PF00627.31 KXZ46241.1 - 0.058 13.3 0.9 0.21 11.5 0.9 1.9 1 0 0 1 1 1 0 UBA/TS-N domain 7tm_6 PF02949.20 KXZ46241.1 - 0.75 8.8 1.5 1.1 8.3 1.5 1.1 1 0 0 1 1 1 0 7tm Odorant receptor RAP1 PF07218.11 KXZ46242.1 - 0.012 14.0 0.0 0.012 14.0 0.0 1.8 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.14 KXZ46242.1 - 0.047 12.0 15.2 0.076 11.3 15.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 KXZ46242.1 - 0.78 8.2 6.8 0.94 7.9 6.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 RR_TM4-6 PF06459.12 KXZ46242.1 - 1.3 8.8 19.6 2.9 7.7 19.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF3_subunit PF08597.10 KXZ46242.1 - 1.3 8.8 24.1 2.8 7.8 24.1 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Otopetrin PF03189.13 KXZ46242.1 - 1.6 7.4 3.4 2.2 7.0 3.4 1.2 1 0 0 1 1 1 0 Otopetrin DUF4638 PF15472.6 KXZ46242.1 - 1.9 8.1 18.2 3.6 7.2 18.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Zip PF02535.22 KXZ46242.1 - 2 7.6 6.0 2.9 7.0 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FapA PF03961.13 KXZ46242.1 - 2.3 6.7 15.1 3.5 6.1 15.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Plasmodium_Vir PF05795.11 KXZ46242.1 - 2.6 7.4 7.2 4.4 6.6 7.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Relaxase PF03432.14 KXZ46242.1 - 3.5 7.2 17.6 5.9 6.4 17.6 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain MDM10 PF12519.8 KXZ46242.1 - 3.5 6.4 14.9 5.4 5.8 14.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GREB1 PF15782.5 KXZ46242.1 - 3.8 4.5 9.5 5.3 4.0 9.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 KXZ46242.1 - 4.9 5.8 21.1 9 4.9 21.1 1.3 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 KXZ46242.1 - 5.9 5.7 11.9 11 4.9 11.9 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Response_reg PF00072.24 KXZ46245.1 - 5.7e-55 184.3 0.0 8.7e-29 100.0 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 KXZ46245.1 - 2e-29 102.4 0.3 2e-29 102.4 0.3 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bac_rhodopsin PF01036.18 KXZ46245.1 - 6.4e-16 58.6 15.0 1e-15 57.9 15.0 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HisKA PF00512.25 KXZ46245.1 - 1e-14 54.3 0.5 1.2e-12 47.7 0.0 3.5 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 KXZ46245.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 GHKL domain DUF1631 PF07793.11 KXZ46245.1 - 1.2 7.4 12.0 2.8 6.2 12.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SpoU_methylase PF00588.19 KXZ46246.1 - 1e-22 80.8 0.0 1.4e-12 48.0 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family WD40 PF00400.32 KXZ46248.1 - 1.7e-10 41.3 11.2 0.46 11.4 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KXZ46248.1 - 0.12 12.9 9.0 9.1 6.9 0.0 4.8 3 2 2 5 5 5 0 PQQ-like domain zf-MYND PF01753.18 KXZ46249.1 - 2.1e-07 30.9 5.3 3.3e-07 30.3 5.3 1.3 1 0 0 1 1 1 1 MYND finger FYVE_2 PF02318.16 KXZ46249.1 - 0.0057 16.9 1.7 0.0071 16.5 1.7 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 KXZ46249.1 - 1 9.3 9.0 0.092 12.6 1.6 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Corona_7 PF02398.16 KXZ46250.1 - 2 9.1 3.8 30 5.3 0.3 2.5 2 0 0 2 2 2 0 Coronavirus protein 7 F-box PF00646.33 KXZ46251.1 - 9.5e-07 28.6 0.5 1.8e-06 27.7 0.5 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXZ46251.1 - 2e-06 27.6 3.6 3.6e-06 26.8 3.6 1.4 1 0 0 1 1 1 1 F-box-like ARTD15_N PF18084.1 KXZ46253.1 - 2.4e-14 53.3 0.0 2.2e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 ARTD15 N-terminal domain PARP PF00644.20 KXZ46253.1 - 1.3e-10 41.2 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Exotox-A_cataly PF09009.10 KXZ46253.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A catalytic HAUS6_N PF14661.6 KXZ46254.1 - 4.2e-15 55.9 0.0 6.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus AAA_lid_2 PF17863.1 KXZ46254.1 - 0.074 12.9 4.3 0.35 10.7 4.3 2.2 1 0 0 1 1 1 0 AAA lid domain Guanylate_cyc PF00211.20 KXZ46255.1 - 5.7e-55 185.8 0.0 8.9e-55 185.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Nop10p PF04135.12 KXZ46256.1 - 0.49 10.5 20.0 13 5.9 0.1 6.5 6 0 0 6 6 6 0 Nucleolar RNA-binding protein, Nop10p family Nop10p PF04135.12 KXZ46257.1 - 0.047 13.7 19.5 13 5.9 0.1 6.7 6 0 0 6 6 6 0 Nucleolar RNA-binding protein, Nop10p family Lectin_C PF00059.21 KXZ46258.1 - 0.00012 22.7 9.8 6.2 7.6 0.1 5.3 3 2 2 5 5 5 5 Lectin C-type domain DUF1929 PF09118.11 KXZ46260.1 - 3.3e-23 81.8 0.2 1.1e-22 80.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 KXZ46260.1 - 1.9e-10 40.4 0.0 7.1e-09 35.2 0.0 2.7 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 KXZ46260.1 - 0.078 13.0 0.2 8.7 6.5 0.2 2.8 2 0 0 2 2 2 0 Kelch motif GalKase_gal_bdg PF10509.9 KXZ46261.1 - 5.2e-23 80.3 0.1 8.9e-23 79.6 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KXZ46261.1 - 9.8e-12 44.9 4.7 2e-11 44.0 4.7 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Oscp1 PF10188.9 KXZ46265.1 - 5.1e-66 222.1 0.9 6.3e-66 221.8 0.9 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 SET PF00856.28 KXZ46266.1 - 2.9e-18 66.8 0.1 6.1e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 SET domain YihI PF04220.12 KXZ46266.1 - 0.012 15.4 2.3 0.027 14.2 2.3 1.6 1 0 0 1 1 1 0 Der GTPase activator (YihI) Suf PF05843.14 KXZ46266.1 - 0.64 9.9 2.4 1 9.3 2.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 KXZ46266.1 - 6.6 6.3 9.9 11 5.5 9.9 1.2 1 0 0 1 1 1 0 Spt20 family WSC PF01822.19 KXZ46267.1 - 1.1e-15 57.6 19.1 1.9e-10 40.8 3.5 3.1 3 0 0 3 3 3 2 WSC domain Gal_Lectin PF02140.18 KXZ46267.1 - 4.2e-14 52.7 2.1 4.2e-14 52.7 2.1 2.5 2 0 0 2 2 2 1 Galactose binding lectin domain F5_F8_type_C PF00754.25 KXZ46267.1 - 0.00027 21.0 0.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain Mito_fiss_reg PF05308.11 KXZ46267.1 - 0.31 11.1 1.1 0.64 10.1 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator U-box PF04564.15 KXZ46268.1 - 2.1e-17 63.0 0.0 3.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain MIB_HERC2 PF06701.13 KXZ46268.1 - 9.2e-08 32.2 12.0 0.00057 20.1 5.5 3.8 3 0 0 3 3 3 3 Mib_herc2 zf-Nse PF11789.8 KXZ46268.1 - 0.006 16.4 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit UMP1 PF05348.11 KXZ46268.1 - 0.051 13.8 0.9 0.093 13.0 0.9 1.4 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 GAS PF13851.6 KXZ46269.1 - 0.012 15.0 1.7 0.017 14.5 1.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HTH_5 PF01022.20 KXZ46269.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Jnk-SapK_ap_N PF09744.9 KXZ46269.1 - 0.026 14.8 2.8 0.044 14.0 2.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KXZ46269.1 - 0.17 12.4 4.4 0.28 11.7 4.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region KASH_CCD PF14662.6 KXZ46269.1 - 0.28 11.0 4.8 0.47 10.3 4.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HSP70 PF00012.20 KXZ46270.1 - 0.00024 19.4 0.0 0.00039 18.7 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ46270.1 - 0.0022 16.9 0.0 0.0048 15.7 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 KXZ46271.1 - 6.2e-05 21.4 0.0 0.00025 19.4 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ46271.1 - 0.19 10.5 0.0 0.52 9.1 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein DUF1731 PF08338.11 KXZ46272.1 - 0.16 11.9 0.3 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) FAA_hydrolase PF01557.18 KXZ46273.1 - 1.2e-54 185.2 0.0 2e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXZ46273.1 - 3.1e-24 85.2 0.0 6.9e-24 84.1 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Exo_endo_phos PF03372.23 KXZ46276.1 - 0.00072 19.1 0.2 0.0023 17.5 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Chordopox_E11 PF06138.12 KXZ46279.1 - 0.025 14.9 0.1 0.043 14.2 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus E11 protein Fungus-induced PF10917.8 KXZ46279.1 - 0.29 11.5 3.1 1.1 9.6 3.1 2.0 1 0 0 1 1 1 0 Fungus-induced protein Histidinol_dh PF00815.20 KXZ46279.1 - 4.7 6.1 4.9 7 5.5 4.9 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase Glyco_hydro_18 PF00704.28 KXZ46280.1 - 2.4e-12 47.2 0.0 2.9e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.22 KXZ46282.1 - 7.8e-64 216.1 0.0 9.8e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COX17 PF05051.13 KXZ46283.1 - 1.9e-18 66.5 7.0 2.4e-18 66.2 7.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Methyltransf_31 PF13847.6 KXZ46284.1 - 1.1e-27 96.7 0.0 1.9e-27 95.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ46284.1 - 6.9e-19 68.4 0.0 2.5e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ46284.1 - 6.1e-16 58.9 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ46284.1 - 2.5e-12 46.9 0.0 3.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ46284.1 - 3.9e-11 42.7 0.0 5.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXZ46284.1 - 3.4e-10 40.5 0.0 6.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXZ46284.1 - 1.6e-05 24.7 0.1 2.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXZ46284.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 KXZ46284.1 - 0.0022 17.9 0.2 0.1 12.4 0.0 2.1 1 1 1 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 KXZ46284.1 - 0.014 15.0 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KXZ46284.1 - 0.049 13.7 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 KXZ46284.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 KXZ46284.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Glyco_transf_24 PF18404.1 KXZ46285.1 - 2.3e-141 469.9 3.1 2.7e-141 469.6 3.1 1.0 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_8 PF01501.20 KXZ46285.1 - 4e-08 33.1 0.6 6.1e-08 32.5 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Thioredoxin_14 PF18402.1 KXZ46286.1 - 0.0016 18.5 0.0 0.0017 18.4 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KXZ46287.1 - 5.9e-29 101.3 0.0 9.1e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Abhydrolase_8 PF06259.12 KXZ46287.1 - 0.048 13.3 0.9 0.31 10.7 0.1 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase TP_methylase PF00590.20 KXZ46288.1 - 2.8e-17 63.4 0.2 3.7e-17 63.0 0.2 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sld5 PF05916.11 KXZ46289.1 - 0.0012 19.2 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 KXZ46290.1 - 7.3e-13 48.5 0.4 8e-13 48.4 0.4 1.0 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus SBP PF03110.14 KXZ46292.1 - 9.4e-24 83.5 4.5 2.2e-23 82.3 4.5 1.6 1 0 0 1 1 1 1 SBP domain TFIIA PF03153.13 KXZ46292.1 - 3.8 7.4 40.8 0.054 13.5 24.8 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CAAD PF14159.6 KXZ46293.1 - 1.2e-30 105.1 0.0 1.6e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase peroxidase PF00141.23 KXZ46294.1 - 6.9e-16 58.6 0.3 1.2e-15 57.9 0.3 1.3 1 0 0 1 1 1 1 Peroxidase CytB6-F_Fe-S PF08802.10 KXZ46294.1 - 4.7 7.3 10.7 0.32 11.1 1.4 3.0 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit DUF676 PF05057.14 KXZ46295.1 - 2.7e-37 128.4 0.0 4.1e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) HGTP_anticodon PF03129.20 KXZ46296.1 - 4.2e-21 74.9 0.3 1.6e-20 73.0 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXZ46296.1 - 4.4e-11 43.1 0.0 1.3e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 KXZ46296.1 - 0.07 13.3 6.7 2 8.6 5.7 3.2 2 1 0 2 2 2 0 WHEP-TRS domain CP12 PF02672.15 KXZ46296.1 - 5.3 7.9 7.6 1.6 9.5 3.0 2.5 2 0 0 2 2 2 0 CP12 domain Pkinase PF00069.25 KXZ46298.1 - 9.4e-51 172.7 0.0 1e-18 67.7 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46298.1 - 4.6e-18 65.4 0.0 1.9e-14 53.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KXZ46298.1 - 7.3e-05 22.8 0.1 7.3e-05 22.8 0.1 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ46298.1 - 0.04 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like hnRNP_Q_AcD PF18360.1 KXZ46300.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Pkinase_Tyr PF07714.17 KXZ46301.1 - 1.4e-10 40.9 0.0 6.1e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ46301.1 - 5.8e-07 29.1 0.0 2.1e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF1631 PF07793.11 KXZ46301.1 - 0.044 12.2 2.2 0.051 12.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Oxidored_q6 PF01058.22 KXZ46301.1 - 0.14 12.0 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF2282 PF10048.9 KXZ46301.1 - 0.16 12.0 1.2 0.29 11.2 1.2 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) His_Phos_1 PF00300.22 KXZ46302.1 - 2.7e-29 102.3 1.2 5.5e-20 71.9 0.2 3.1 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 KXZ46303.1 - 1.8e-66 224.8 0.0 1.3e-52 179.1 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 PSD3 PF07626.11 KXZ46303.1 - 5.2 7.6 5.3 2.5 8.6 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) DnaJ PF00226.31 KXZ46304.1 - 4e-19 68.5 0.1 4e-18 65.3 0.1 2.1 1 1 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 KXZ46307.1 - 4.4e-67 226.2 0.1 5.9e-67 225.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46307.1 - 1.9e-44 151.9 0.0 2.5e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46307.1 - 1.1e-07 31.5 0.1 3.2e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXZ46307.1 - 0.0031 16.4 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SIX1_SD PF16878.5 KXZ46307.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain Haspin_kinase PF12330.8 KXZ46307.1 - 0.12 11.3 2.9 0.089 11.7 1.4 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KXZ46307.1 - 0.13 11.6 0.2 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cwf_Cwc_15 PF04889.12 KXZ46307.1 - 0.23 11.1 5.0 0.36 10.5 5.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Coa1 PF08695.10 KXZ46308.1 - 5.8e-05 22.8 1.2 8.6e-05 22.3 0.0 1.9 2 1 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.11 KXZ46308.1 - 0.0025 17.7 0.0 0.012 15.4 0.0 2.0 1 1 0 1 1 1 1 TIM21 DUF2070 PF09843.9 KXZ46309.1 - 2.2 6.5 10.7 2.6 6.2 10.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Radial_spoke PF04712.12 KXZ46311.1 - 0.42 9.5 7.6 0.51 9.2 7.6 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein VESA1_N PF12785.7 KXZ46311.1 - 1.3 7.9 19.1 1.3 7.9 19.1 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Peptidase_M11 PF05548.11 KXZ46312.1 - 0.035 13.3 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Gametolysin peptidase M11 ACOX PF01756.19 KXZ46313.1 - 1e-22 80.6 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KXZ46313.1 - 0.016 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain His_Phos_1 PF00300.22 KXZ46314.1 - 3.8e-07 30.0 0.0 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) EF-hand_1 PF00036.32 KXZ46315.1 - 9.4e-10 37.4 0.6 3.7e-08 32.4 0.4 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXZ46315.1 - 1.7e-09 37.4 0.0 2.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KXZ46315.1 - 1.3e-08 35.1 0.0 1.9e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ46315.1 - 4.3e-06 26.2 0.2 0.00032 20.4 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KXZ46315.1 - 1.9e-05 23.9 0.8 0.00093 18.6 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 KXZ46315.1 - 0.00071 19.8 0.0 0.00096 19.4 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain CNOT1_TTP_bind PF16417.5 KXZ46315.1 - 0.056 12.6 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Pyr_redox_2 PF07992.14 KXZ46316.1 - 1.8e-38 132.5 0.0 2.7e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ46316.1 - 3.4e-08 33.9 0.3 1.3e-07 32.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ46317.1 - 5.6e-40 137.4 0.0 8.1e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ46317.1 - 7.7e-11 42.4 0.5 3e-10 40.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ46318.1 - 1.4e-43 149.2 0.0 2.2e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ46318.1 - 3.7e-10 40.2 0.5 1.5e-09 38.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXZ46319.1 - 7.5e-46 156.6 0.0 2.5e-45 154.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46319.1 - 2.8e-21 76.0 0.2 1e-20 74.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46319.1 - 1.2e-05 24.8 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 KXZ46319.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.22 KXZ46320.1 - 1.7e-38 132.5 0.1 4e-38 131.3 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 PSD3 PF07626.11 KXZ46320.1 - 0.092 13.2 2.6 0.3 11.6 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1587) p450 PF00067.22 KXZ46321.1 - 8.8e-14 51.1 0.0 4.9e-11 42.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_18 PF00704.28 KXZ46323.1 - 6.5e-52 177.2 0.0 1.5e-50 172.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXZ46323.1 - 3.3e-18 65.9 129.7 7.4e-05 23.1 21.4 6.3 6 0 0 6 6 6 5 Chitin recognition protein Per1 PF04080.13 KXZ46323.1 - 0.026 14.3 0.7 0.05 13.4 0.7 1.5 1 0 0 1 1 1 0 Per1-like family LPD16 PF18830.1 KXZ46323.1 - 0.2 11.6 0.0 34 4.5 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 16 RPN7 PF10602.9 KXZ46324.1 - 1.9e-42 144.9 0.0 3.1e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXZ46324.1 - 7.4e-15 55.3 0.0 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain RP-C PF03428.13 KXZ46324.1 - 0.046 13.4 0.9 0.072 12.7 0.3 1.7 2 0 0 2 2 2 0 Replication protein C N-terminal domain TcdB_toxin_midN PF12256.8 KXZ46324.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DDRGK PF09756.9 KXZ46324.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.6 2 0 0 2 2 2 0 DDRGK domain vATP-synt_AC39 PF01992.16 KXZ46325.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Ank_2 PF12796.7 KXZ46326.1 - 9.9e-07 29.3 0.2 0.00029 21.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) R3H PF01424.22 KXZ46326.1 - 4.1e-05 23.5 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 R3H domain Ank_3 PF13606.6 KXZ46326.1 - 0.00071 19.8 0.3 0.29 11.8 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXZ46326.1 - 0.003 17.8 0.9 5.4 7.5 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46326.1 - 0.0077 16.6 0.5 0.1 13.1 0.5 2.6 1 1 0 1 1 1 1 Ankyrin repeat MASE1 PF05231.14 KXZ46330.1 - 4.7 6.3 11.0 0.16 11.1 1.5 2.2 2 0 0 2 2 2 0 MASE1 Ank_4 PF13637.6 KXZ46332.1 - 2.6e-14 53.4 0.1 0.00047 20.7 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ46332.1 - 2.9e-13 49.7 2.9 0.0016 18.7 0.1 3.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ46332.1 - 2.2e-11 44.2 0.7 4.9e-06 27.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ46332.1 - 9.5e-11 41.6 2.8 0.4 11.2 0.0 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KXZ46332.1 - 2.4e-08 33.6 0.5 5.7 7.8 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat ABC_trans_aux PF03886.13 KXZ46332.1 - 0.045 13.3 0.5 0.084 12.4 0.5 1.5 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component Phage_Gp19 PF09355.10 KXZ46332.1 - 0.047 14.1 0.9 0.089 13.2 0.9 1.6 1 1 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 Ank_2 PF12796.7 KXZ46333.1 - 3.6e-32 110.8 16.8 3.1e-08 34.1 0.0 6.8 3 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46333.1 - 6.1e-31 106.4 18.9 1.3e-06 28.8 0.0 11.6 4 4 9 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46333.1 - 7.2e-27 92.6 32.3 0.0028 18.0 0.1 13.5 13 3 1 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 KXZ46333.1 - 3.3e-21 75.1 22.8 8.5e-08 32.3 0.2 8.8 6 2 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46333.1 - 1.3e-13 49.8 20.5 0.22 12.2 0.0 12.2 14 0 0 14 14 14 4 Ankyrin repeat Ank_2 PF12796.7 KXZ46334.1 - 7.7e-37 125.7 18.5 4.6e-06 27.1 0.2 10.6 3 2 8 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46334.1 - 2.5e-28 98.1 18.6 0.0033 18.0 0.0 15.5 11 4 6 17 17 17 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ46334.1 - 3.8e-25 87.6 30.8 0.0013 18.9 0.2 14.6 12 4 5 17 17 17 10 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46334.1 - 2.3e-18 65.7 46.4 0.00031 21.0 0.0 15.2 17 1 0 17 17 17 5 Ankyrin repeat Ank_3 PF13606.6 KXZ46334.1 - 1.8e-15 55.5 14.9 3.1 8.6 0.0 15.5 16 0 0 16 16 16 3 Ankyrin repeat SHOCT PF09851.9 KXZ46334.1 - 0.084 12.6 2.4 0.21 11.4 2.4 1.7 1 0 0 1 1 1 0 Short C-terminal domain XK-related PF09815.9 KXZ46335.1 - 2.5e-08 33.4 0.3 3.8e-08 32.8 0.3 1.2 1 0 0 1 1 1 1 XK-related protein LRR_6 PF13516.6 KXZ46335.1 - 0.00014 21.6 0.2 0.0036 17.2 0.1 2.9 2 0 0 2 2 2 1 Leucine Rich repeat LRR_6 PF13516.6 KXZ46336.1 - 0.047 13.8 0.0 3.8 7.8 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat Ank_2 PF12796.7 KXZ46337.1 - 3.6e-183 594.7 60.4 2e-17 63.5 0.2 11.7 4 2 10 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46337.1 - 1.9e-135 439.7 18.6 9.5e-12 45.2 0.0 16.5 8 5 7 16 16 16 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ46337.1 - 3.8e-120 390.4 55.8 1.5e-12 47.5 0.4 19.2 6 5 14 20 20 20 19 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46337.1 - 2.5e-116 375.5 62.6 2.3e-06 27.8 0.0 23.5 23 0 0 23 23 23 23 Ankyrin repeat Ank_3 PF13606.6 KXZ46337.1 - 5.7e-108 339.7 31.7 5.5e-05 23.2 0.0 23.6 24 0 0 24 24 24 22 Ankyrin repeat GP24_25 PF17388.2 KXZ46337.1 - 0.043 13.8 0.1 15 5.5 0.0 3.5 4 0 0 4 4 4 0 Tail assembly gene products 24 & 25 DUF1018 PF06252.12 KXZ46337.1 - 0.055 14.5 0.0 60 4.7 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1018) Glyoxalase_4 PF13669.6 KXZ46337.1 - 0.16 12.3 6.4 0.59 10.4 0.1 4.3 5 1 0 5 5 5 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Shigella_OspC PF06128.11 KXZ46337.1 - 0.24 11.1 0.0 5.3 6.7 0.0 2.8 3 0 0 3 3 3 0 Shigella flexneri OspC protein DUF2188 PF09954.9 KXZ46337.1 - 0.5 10.5 4.3 0.14 12.3 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) PBP1_TM PF14812.6 KXZ46339.1 - 0.026 14.9 2.9 0.074 13.4 2.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GRP PF07172.11 KXZ46340.1 - 0.046 14.4 16.7 0.1 13.3 16.7 1.5 1 0 0 1 1 1 0 Glycine rich protein family JAB PF01398.21 KXZ46341.1 - 9.7e-33 112.7 0.0 1.8e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXZ46341.1 - 8.4e-10 39.1 0.1 1.5e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KXZ46341.1 - 1.4e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FliG_C PF01706.16 KXZ46341.1 - 0.054 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 FliG C-terminal domain SYCE1 PF15233.6 KXZ46344.1 - 0.11 12.5 3.9 0.14 12.2 0.2 2.2 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Ribosomal_S5_C PF03719.15 KXZ46345.1 - 3.7e-12 45.5 0.0 7.4e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXZ46345.1 - 1.3e-07 31.5 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Methyltransf_25 PF13649.6 KXZ46346.1 - 7.6e-18 65.0 0.0 1.6e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ46346.1 - 4.5e-14 52.9 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ46346.1 - 2.5e-12 46.9 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ46346.1 - 4.3e-10 40.2 0.0 7.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ46346.1 - 4.8e-09 36.3 0.0 6.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ46346.1 - 2.5e-05 23.7 0.0 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KXZ46346.1 - 0.0013 17.8 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 KXZ46346.1 - 0.022 15.8 0.0 0.052 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GHMP_kinases_N PF00288.26 KXZ46350.1 - 4.3e-12 46.1 0.1 1.1e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Ala_racemase_N PF01168.20 KXZ46351.1 - 4.1e-23 82.2 0.0 4.9e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MRP-L27 PF09809.9 KXZ46352.1 - 0.00053 19.8 0.0 0.00066 19.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Bac_DNA_binding PF00216.21 KXZ46353.1 - 1.2e-29 102.3 0.4 1.7e-29 101.9 0.4 1.2 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 KXZ46353.1 - 1.7e-05 24.9 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 KXZ46353.1 - 0.0093 16.1 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 KXZ46353.1 - 0.025 14.7 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 KXZ46353.1 - 0.037 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 ARGLU PF15346.6 KXZ46355.1 - 2.1e-16 60.1 36.2 2.2e-16 60.1 35.3 1.5 1 1 0 1 1 1 1 Arginine and glutamate-rich 1 U79_P34 PF03064.16 KXZ46355.1 - 0.033 13.6 8.3 0.037 13.4 8.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Trehalase PF01204.18 KXZ46355.1 - 0.28 10.0 6.4 0.35 9.7 6.4 1.1 1 0 0 1 1 1 0 Trehalase DUF1993 PF09351.10 KXZ46355.1 - 1.3 9.2 8.7 1.7 8.8 8.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) DUF1053 PF06327.14 KXZ46355.1 - 2.4 8.8 9.8 3.9 8.1 0.2 2.7 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1053) CheD PF03975.13 KXZ46359.1 - 0.089 12.9 1.1 0.43 10.7 0.4 2.5 2 0 0 2 2 2 0 CheD chemotactic sensory transduction Pkinase PF00069.25 KXZ46360.1 - 1.1e-73 247.8 0.0 1.4e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46360.1 - 1.8e-35 122.5 0.0 2.3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXZ46360.1 - 0.00014 20.9 0.1 0.00022 20.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXZ46360.1 - 0.00015 21.1 0.3 0.00025 20.5 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ46360.1 - 0.0014 18.0 0.2 0.027 13.8 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KXZ46360.1 - 0.021 14.7 0.7 0.17 11.7 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXZ46360.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 EMG1 PF03587.14 KXZ46361.1 - 1.9e-73 246.2 0.0 2.3e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Pkinase PF00069.25 KXZ46363.1 - 3.4e-54 184.0 0.0 4.3e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46363.1 - 7.1e-31 107.4 0.0 9.8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ46363.1 - 8.6e-07 28.1 0.0 1.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ46363.1 - 0.00023 20.6 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ46363.1 - 0.043 13.2 0.5 0.09 12.1 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ46363.1 - 0.11 12.4 1.3 0.53 10.2 0.4 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Codanin-1_C PF15296.6 KXZ46365.1 - 1.5e-05 25.0 0.0 0.00025 21.1 0.0 2.8 2 1 0 2 2 2 1 Codanin-1 C-terminus Pkinase_Tyr PF07714.17 KXZ46367.1 - 3.7e-26 92.0 0.0 1.6e-24 86.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ46367.1 - 1.5e-24 86.8 0.0 1.6e-23 83.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DHO_dh PF01180.21 KXZ46368.1 - 2.8e-13 49.7 3.6 6.1e-06 25.7 0.2 3.7 4 0 0 4 4 4 3 Dihydroorotate dehydrogenase SLBP_RNA_bind PF15247.6 KXZ46369.1 - 5.8e-31 106.4 1.9 1e-30 105.6 1.9 1.4 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain LZ3wCH PF18517.1 KXZ46370.1 - 1.6e-12 47.4 0.1 2.9e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Leucine zipper with capping helix domain DUF99 PF01949.16 KXZ46370.1 - 0.017 14.6 0.2 0.06 12.8 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF99 PMT2_N PF17987.1 KXZ46370.1 - 0.062 13.5 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Cyclin_N PF00134.23 KXZ46371.1 - 7.6e-08 32.2 0.4 6e-06 26.0 0.0 2.8 2 1 1 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ46371.1 - 1.2e-07 31.9 0.0 5.2e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Phage_term_smal PF05944.12 KXZ46372.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage small terminase subunit SpoIIE PF07228.12 KXZ46374.1 - 7.3e-07 29.3 0.8 1.1e-05 25.5 0.8 3.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) BPL_LplA_LipB PF03099.19 KXZ46374.1 - 8.7e-07 28.9 0.0 2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PP2C PF00481.21 KXZ46374.1 - 0.00013 21.6 0.0 0.11 12.1 0.0 3.1 2 0 0 2 2 2 2 Protein phosphatase 2C DUF4162 PF13732.6 KXZ46374.1 - 0.47 11.2 4.2 3.2 8.5 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) Surfac_D-trimer PF09006.11 KXZ46374.1 - 6.1 6.8 10.5 0.079 12.9 0.6 3.1 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Spc7 PF08317.11 KXZ46375.1 - 0.065 12.1 0.9 0.1 11.5 0.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COMM_domain PF07258.14 KXZ46375.1 - 0.073 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 COMM domain Cep57_CLD_2 PF14197.6 KXZ46375.1 - 0.082 13.0 4.8 0.19 11.9 4.8 1.7 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4200 PF13863.6 KXZ46375.1 - 0.083 13.3 2.6 0.12 12.8 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HHH_8 PF14716.6 KXZ46375.1 - 0.099 13.0 0.5 0.34 11.3 0.2 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix domain ZapB PF06005.12 KXZ46375.1 - 0.11 13.0 0.4 0.11 13.0 0.4 2.4 2 1 1 3 3 3 0 Cell division protein ZapB Phage_GP20 PF06810.11 KXZ46375.1 - 0.15 11.9 1.3 15 5.3 0.2 2.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 Bap31_Bap29_C PF18035.1 KXZ46375.1 - 0.48 10.5 2.7 18 5.4 0.6 2.6 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Uso1_p115_C PF04871.13 KXZ46375.1 - 0.57 10.6 6.1 0.25 11.7 3.7 1.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Acetyltransf_1 PF00583.25 KXZ46376.1 - 1.2e-11 44.9 0.1 7.8e-11 42.2 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ46376.1 - 2.3e-09 37.2 0.0 4.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ46376.1 - 2.4e-09 37.5 0.0 3.9e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ46376.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KXZ46376.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KXZ46376.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ46376.1 - 0.033 14.3 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase_Tyr PF07714.17 KXZ46377.1 - 1.8e-32 112.7 0.0 7e-17 61.6 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ46377.1 - 1.8e-29 102.9 0.0 1.8e-20 73.5 0.0 3.0 2 1 1 3 3 3 3 Protein kinase domain APH PF01636.23 KXZ46377.1 - 0.00085 19.3 0.4 0.037 13.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 KXZ46378.1 - 1.1e-30 105.7 0.1 2e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ46378.1 - 6.2e-20 71.4 0.0 1.3e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ46378.1 - 6.1e-17 61.9 0.0 2.2e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KXZ46379.1 - 2.1e-15 56.6 0.1 5.8e-15 55.1 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KXZ46379.1 - 1.1e-12 48.2 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain PHD PF00628.29 KXZ46379.1 - 2.4e-07 30.5 2.1 2.4e-07 30.5 2.1 3.0 3 0 0 3 3 3 1 PHD-finger zf-H2C2 PF09337.10 KXZ46379.1 - 0.00047 20.3 0.1 0.0025 18.0 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger zf-RING-like PF08746.11 KXZ46379.1 - 0.0066 16.7 3.3 1.6 9.1 0.8 2.5 2 0 0 2 2 2 2 RING-like domain rve_3 PF13683.6 KXZ46379.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DUF1799 PF08809.11 KXZ46380.1 - 0.11 12.7 0.3 0.2 11.9 0.3 1.4 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) DUF3597 PF12200.8 KXZ46381.1 - 0.021 15.4 0.5 0.14 12.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) Spc7 PF08317.11 KXZ46382.1 - 0.0017 17.3 1.0 0.002 17.0 1.0 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Rootletin PF15035.6 KXZ46382.1 - 0.0071 16.4 0.4 0.0082 16.2 0.4 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Cgr1 PF03879.14 KXZ46382.1 - 0.013 15.9 2.5 0.018 15.4 2.5 1.1 1 0 0 1 1 1 0 Cgr1 family DUF4472 PF14739.6 KXZ46382.1 - 0.047 14.4 1.7 0.061 14.1 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Mto2_bdg PF12808.7 KXZ46382.1 - 0.31 11.3 11.3 0.12 12.7 8.5 1.7 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region OEP PF02321.18 KXZ46382.1 - 1.6 8.5 10.5 2 8.2 10.5 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein DUF4140 PF13600.6 KXZ46382.1 - 3.1 8.3 8.2 19 5.8 8.2 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HMMR_N PF15905.5 KXZ46383.1 - 0.00047 19.7 3.5 0.00047 19.7 3.5 3.8 2 2 1 3 3 3 1 Hyaluronan mediated motility receptor N-terminal Shugoshin_N PF07558.11 KXZ46383.1 - 0.0032 17.3 0.1 0.13 12.1 0.0 3.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Fez1 PF06818.15 KXZ46383.1 - 0.011 16.1 27.4 3.2 8.2 6.6 3.7 1 1 2 3 3 3 0 Fez1 bZIP_1 PF00170.21 KXZ46383.1 - 0.012 15.7 0.0 0.012 15.7 0.0 4.5 5 0 0 5 5 3 0 bZIP transcription factor Surfac_D-trimer PF09006.11 KXZ46383.1 - 0.024 14.5 0.6 0.024 14.5 0.6 4.7 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation Snapin_Pallidin PF14712.6 KXZ46383.1 - 0.11 13.0 15.7 0.46 10.9 0.1 5.3 5 1 0 5 5 5 0 Snapin/Pallidin Spc29 PF17082.5 KXZ46383.1 - 0.44 10.4 5.1 7.8 6.3 0.3 3.1 2 1 0 2 2 2 0 Spindle Pole Component 29 DUF1664 PF07889.12 KXZ46383.1 - 0.5 10.4 8.3 3.2 7.8 0.2 4.0 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) YabA PF06156.13 KXZ46383.1 - 1.4 9.6 9.1 47 4.7 1.6 4.4 3 2 0 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 KXZ46383.1 - 2.4 7.0 40.6 0.84 8.5 9.6 4.2 3 1 1 4 4 4 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KXZ46383.1 - 2.9 8.2 12.4 31 4.9 0.2 5.2 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KXZ46383.1 - 3.2 7.9 5.5 14 5.8 0.0 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family IFT57 PF10498.9 KXZ46383.1 - 3.5 6.5 12.6 15 4.4 0.1 4.0 4 1 1 5 5 5 0 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.8 KXZ46383.1 - 3.8 7.6 26.9 5.1 7.2 1.1 5.4 6 0 0 6 6 6 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KXZ46383.1 - 7.6 6.6 32.3 4.8 7.2 3.4 5.8 3 2 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lectin_N PF03954.14 KXZ46383.1 - 8.6 6.1 9.0 35 4.1 0.1 3.8 3 2 0 3 3 3 0 Hepatic lectin, N-terminal domain Transglut_core2 PF13369.6 KXZ46384.1 - 2.4e-37 127.9 0.0 1.1e-36 125.7 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily BACK PF07707.15 KXZ46384.1 - 1.5e-06 28.2 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch TPR_2 PF07719.17 KXZ46384.1 - 0.015 15.3 2.3 0.076 13.2 2.3 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ46384.1 - 0.021 14.7 0.3 0.05 13.4 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.8 KXZ46384.1 - 0.079 11.9 5.3 0.13 11.1 5.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paf67 PF10255.9 KXZ46384.1 - 0.094 11.7 0.2 0.15 11.0 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Use1 PF09753.9 KXZ46384.1 - 0.21 11.3 8.7 0.37 10.5 8.7 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Presenilin PF01080.17 KXZ46384.1 - 0.3 9.8 7.9 0.61 8.8 7.9 1.4 1 0 0 1 1 1 0 Presenilin Endostatin PF06482.11 KXZ46384.1 - 3.2 7.1 6.1 6.2 6.2 6.1 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4746 PF15928.5 KXZ46384.1 - 4.4 6.7 7.1 8.5 5.7 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Rrn6 PF10214.9 KXZ46384.1 - 4.7 5.6 14.3 8.8 4.7 14.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Hid1 PF12722.7 KXZ46384.1 - 6.8 4.7 5.3 9.9 4.1 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KXZ46384.1 - 9.1 4.4 11.1 17 3.5 11.1 1.3 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.12 KXZ46384.1 - 9.3 5.1 12.6 14 4.5 12.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIE PF07228.12 KXZ46385.1 - 6.5e-08 32.7 2.6 1.5e-07 31.5 0.4 2.6 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXZ46385.1 - 2.7e-05 24.0 0.0 0.027 14.1 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXZ46385.1 - 0.0034 17.0 3.1 0.0034 17.0 3.1 3.0 1 1 1 2 2 2 1 Protein phosphatase 2C DnaJ PF00226.31 KXZ46387.1 - 5.6e-17 61.6 0.0 9.5e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 KXZ46387.1 - 5.3e-16 58.9 3.1 1.2e-15 57.7 3.1 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KXZ46387.1 - 9.8e-10 39.0 2.3 2.7e-09 37.6 2.3 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_10 PF13237.6 KXZ46387.1 - 2.2e-05 24.5 1.8 4.4e-05 23.5 1.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXZ46387.1 - 0.0019 18.2 1.8 0.0019 18.2 1.8 1.6 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_7 PF12838.7 KXZ46387.1 - 0.0021 18.6 5.1 0.0035 17.9 2.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KXZ46387.1 - 0.0026 17.5 3.4 0.0026 17.5 3.4 2.1 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 KXZ46387.1 - 0.0043 17.1 2.4 0.0066 16.5 0.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KXZ46387.1 - 0.0046 17.0 3.0 0.0046 17.0 3.0 1.7 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_8 PF13183.6 KXZ46387.1 - 0.0046 17.4 2.2 0.0046 17.4 2.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXZ46387.1 - 0.0057 17.6 0.8 0.057 14.3 0.4 2.4 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KXZ46387.1 - 0.02 15.1 5.1 0.058 13.6 5.1 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain HTH_20 PF12840.7 KXZ46387.1 - 0.085 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Fer4_17 PF13534.6 KXZ46387.1 - 0.37 11.4 5.5 0.55 10.8 3.5 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KXZ46387.1 - 1.7 9.3 5.6 0.31 11.7 1.3 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain SAP PF02037.27 KXZ46388.1 - 0.00011 21.9 0.1 0.00038 20.1 0.0 2.0 2 0 0 2 2 2 1 SAP domain S1-like PF14444.6 KXZ46388.1 - 0.00072 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 S1-like Apt1 PF10351.9 KXZ46388.1 - 0.43 9.4 13.8 0.89 8.3 13.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.17 KXZ46388.1 - 1.6 8.8 5.7 1.4 9.0 1.1 2.7 2 0 0 2 2 2 0 DDHD domain DUF4614 PF15391.6 KXZ46388.1 - 5.4 7.0 15.0 20 5.1 15.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PI3K_1B_p101 PF10486.9 KXZ46388.1 - 7.7 4.2 8.3 12 3.5 8.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SLC12 PF03522.15 KXZ46388.1 - 8.6 5.3 7.8 17 4.3 7.8 1.4 1 0 0 1 1 1 0 Solute carrier family 12 SR-25 PF10500.9 KXZ46390.1 - 0.0012 18.5 33.9 0.0019 17.8 33.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein S1-like PF14444.6 KXZ46390.1 - 0.0033 17.3 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 S1-like GREB1 PF15782.5 KXZ46390.1 - 0.17 9.0 3.0 0.25 8.4 3.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 KXZ46390.1 - 0.44 9.3 15.2 0.58 9.0 15.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 KXZ46390.1 - 3.4 7.4 12.2 6.5 6.5 12.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI3K_1B_p101 PF10486.9 KXZ46390.1 - 3.7 5.2 8.6 5.2 4.7 8.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 KXZ46390.1 - 4.7 5.4 30.1 6.9 4.8 30.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 KXZ46390.1 - 6.3 5.7 9.0 9 5.2 9.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM76 PF16046.5 KXZ46390.1 - 7 5.9 15.3 11 5.3 15.3 1.2 1 0 0 1 1 1 0 FAM76 protein MMR_HSR1 PF01926.23 KXZ46391.1 - 0.00087 19.4 0.0 0.49 10.5 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase PSII_Ycf12 PF05969.11 KXZ46391.1 - 0.4 10.7 2.1 23 5.1 0.2 2.4 2 0 0 2 2 2 0 Photosystem II complex subunit Ycf12 LRR_6 PF13516.6 KXZ46392.1 - 6.6e-11 41.4 8.9 0.16 12.1 0.1 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 KXZ46392.1 - 0.046 14.3 0.6 70 4.6 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat IQ PF00612.27 KXZ46393.1 - 0.0011 18.6 14.0 0.0096 15.6 2.7 4.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif WSC PF01822.19 KXZ46394.1 - 0.12 12.6 0.2 0.24 11.6 0.2 1.5 1 0 0 1 1 1 0 WSC domain LRR_8 PF13855.6 KXZ46395.1 - 7.8e-62 204.9 35.4 1.6e-13 50.2 0.4 11.8 5 3 9 14 14 14 13 Leucine rich repeat LRR_4 PF12799.7 KXZ46395.1 - 3.8e-42 141.6 41.7 8.5e-08 32.4 0.1 15.1 7 5 7 17 17 17 15 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXZ46395.1 - 4.1e-11 42.7 4.2 0.54 9.7 0.1 6.6 5 2 3 8 8 8 4 Leucine-rich repeat LRR_1 PF00560.33 KXZ46395.1 - 1.5e-09 37.1 40.2 1.3 9.9 0.1 17.3 19 1 0 19 19 19 2 Leucine Rich Repeat LRR_6 PF13516.6 KXZ46395.1 - 7.2e-05 22.5 49.3 0.92 9.7 0.3 15.7 18 0 0 18 18 18 3 Leucine Rich repeat MFS_1 PF07690.16 KXZ46396.1 - 2.6e-17 62.8 45.6 1.7e-09 37.1 17.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ46396.1 - 1.6e-06 27.3 15.5 0.00011 21.2 4.3 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXZ46396.1 - 0.0016 17.4 3.6 0.11 11.3 2.9 2.7 2 1 0 2 2 2 2 MFS_1 like family Mito_fiss_reg PF05308.11 KXZ46396.1 - 0.45 10.6 7.3 0.71 9.9 7.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.25 KXZ46399.1 - 1.6e-50 171.9 0.0 2.1e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46399.1 - 1.8e-19 70.0 0.0 2.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mannosyl_trans3 PF11051.8 KXZ46399.1 - 0.00052 19.5 0.0 0.35 10.2 0.0 2.3 1 1 1 2 2 2 2 Mannosyltransferase putative Kdo PF06293.14 KXZ46399.1 - 0.037 13.4 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ46399.1 - 0.2 11.2 0.1 0.33 10.5 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 KXZ46400.1 - 1.3e-37 128.2 4.6 1.7e-10 41.4 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46400.1 - 8.5e-35 118.7 5.0 3.4e-08 33.9 0.1 6.7 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46400.1 - 3.7e-31 103.7 6.9 2.7e-05 24.2 0.0 9.4 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KXZ46400.1 - 1.4e-25 89.0 15.2 2.6e-07 30.8 0.2 8.1 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46400.1 - 2.5e-23 81.4 25.2 1.2e-06 28.6 0.1 8.6 8 1 0 8 8 8 5 Ankyrin repeat Nuf2 PF03800.14 KXZ46401.1 - 2e-37 128.4 0.6 4.2e-37 127.4 0.6 1.5 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KXZ46401.1 - 3.2e-12 46.5 12.4 3.2e-12 46.5 12.4 4.2 2 2 0 3 3 3 1 Designed helical repeat protein 10 domain GIT_CC PF16559.5 KXZ46401.1 - 0.089 12.7 0.4 0.089 12.7 0.4 4.2 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor LMBR1 PF04791.16 KXZ46401.1 - 1.4 7.7 9.4 1.9 7.3 9.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 KXZ46401.1 - 4.7 7.7 38.5 0.049 14.2 10.9 3.3 2 1 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 KXZ46401.1 - 6.2 6.0 14.7 3.6 6.7 3.8 2.3 2 0 0 2 2 2 0 TMPIT-like protein Pkinase_Tyr PF07714.17 KXZ46402.1 - 4.2e-13 49.2 0.0 1.1e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ46402.1 - 9.6e-11 41.5 0.0 2.6e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain VWA_CoxE PF05762.14 KXZ46402.1 - 0.014 14.8 0.4 0.025 14.0 0.4 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Fer4_9 PF13187.6 KXZ46402.1 - 0.092 12.9 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF4157 PF13699.6 KXZ46402.1 - 1.8 8.9 5.6 0.42 10.9 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) Myc_N PF01056.18 KXZ46403.1 - 0.019 14.9 1.0 0.03 14.2 1.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region AC_N PF16214.5 KXZ46403.1 - 5.3 6.1 6.1 9.3 5.2 6.1 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region AKAP7_NLS PF10469.9 KXZ46404.1 - 2.4e-30 106.0 0.0 3.2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 KXZ46404.1 - 0.00012 21.8 0.1 0.00024 20.8 0.1 1.5 1 0 0 1 1 1 1 KH domain Spore_YhaL PF14147.6 KXZ46404.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL Peptidase_S10 PF00450.22 KXZ46405.1 - 7.2e-85 285.9 0.0 2.9e-83 280.6 0.0 2.7 1 1 0 1 1 1 1 Serine carboxypeptidase Glyco_transf_49 PF13896.6 KXZ46406.1 - 1.9e-27 96.5 0.0 2.2e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Hydrolase_4 PF12146.8 KXZ46407.1 - 1.9e-13 50.3 1.2 3.5e-05 23.2 0.2 3.3 3 0 0 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ46407.1 - 2.7e-08 33.8 0.0 0.00081 19.1 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXZ46407.1 - 0.038 13.6 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 KXZ46407.1 - 0.086 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Lipase_3 PF01764.25 KXZ46407.1 - 0.11 12.3 0.4 0.29 11.0 0.4 1.6 1 0 0 1 1 1 0 Lipase (class 3) LIP PF03583.14 KXZ46407.1 - 0.48 9.7 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase AP2 PF00847.20 KXZ46408.1 - 1.2e-14 54.2 2.2 6e-09 36.0 1.1 2.8 2 0 0 2 2 2 2 AP2 domain DnaJ PF00226.31 KXZ46409.1 - 2.6e-10 40.3 0.7 5.8e-10 39.1 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain SRP-alpha_N PF04086.13 KXZ46409.1 - 4.9 7.0 16.1 6.4 6.6 16.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.25 KXZ46410.1 - 2.6e-32 112.3 0.0 1.8e-19 70.2 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46410.1 - 1e-31 110.2 0.0 2.3e-13 50.0 0.0 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ46412.1 - 3.2e-37 128.2 0.0 3.6e-22 78.9 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ46412.1 - 1.1e-34 120.0 0.0 9.2e-29 100.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Glyco_hydro_2 PF00703.21 KXZ46413.1 - 0.022 15.4 1.3 3.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 2 Pkinase PF00069.25 KXZ46415.1 - 9.6e-54 182.5 0.0 2e-48 165.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain EF-hand_1 PF00036.32 KXZ46415.1 - 1.2e-26 90.3 0.2 2.3e-07 29.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 KXZ46415.1 - 1.1e-23 81.6 1.2 5.9e-06 25.5 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ46415.1 - 1.4e-23 83.1 0.0 3.1e-10 40.3 0.0 2.7 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ46415.1 - 4.8e-20 69.7 0.1 1.3e-06 27.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain Pkinase_Tyr PF07714.17 KXZ46415.1 - 1.4e-17 63.9 0.0 7.6e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_8 PF13833.6 KXZ46415.1 - 7.4e-15 54.5 1.0 2.7e-05 23.9 0.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXZ46415.1 - 2e-07 31.3 0.0 0.0086 16.4 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KXZ46415.1 - 0.0011 19.2 0.1 2.1 8.6 0.0 3.4 3 1 1 4 4 4 1 Dockerin type I domain Kinase-like PF14531.6 KXZ46415.1 - 0.0091 15.3 0.0 0.058 12.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like EF-hand_4 PF12763.7 KXZ46415.1 - 0.014 15.3 0.0 4.2 7.4 0.0 2.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 KXZ46415.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EFhand_Ca_insen PF08726.10 KXZ46415.1 - 0.044 13.9 0.4 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Ca2+ insensitive EF hand APH PF01636.23 KXZ46415.1 - 0.17 11.8 2.8 2.1 8.2 0.0 3.0 2 2 2 4 4 4 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ46415.1 - 0.24 10.1 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase VCBS PF13517.6 KXZ46415.1 - 1 10.0 9.2 9 7.0 1.0 4.0 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TAFII28 PF04719.14 KXZ46416.1 - 1.1e-26 92.7 0.1 1.4e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Cnd3 PF12719.7 KXZ46416.1 - 0.041 13.1 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DUF2999 PF11212.8 KXZ46416.1 - 0.13 12.6 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Acetyltransf_1 PF00583.25 KXZ46417.1 - 1.4e-08 35.0 0.0 2.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ46417.1 - 7.3e-07 29.5 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ46417.1 - 1.2e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXZ46417.1 - 0.0099 16.0 0.0 0.034 14.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ46417.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein SSF PF00474.17 KXZ46420.1 - 4.7e-11 42.2 16.0 3.6e-10 39.3 11.0 2.9 3 0 0 3 3 3 2 Sodium:solute symporter family PAD_porph PF04371.15 KXZ46421.1 - 9.3e-109 363.6 0.0 1.1e-108 363.3 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Syja_N PF02383.18 KXZ46422.1 - 2.9e-41 141.9 0.0 4.2e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain WW PF00397.26 KXZ46422.1 - 2.3e-10 40.4 1.0 2.3e-10 40.4 1.0 2.5 2 0 0 2 2 2 1 WW domain WHEP-TRS PF00458.20 KXZ46422.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 WHEP-TRS domain DNA_topoisoIV PF00521.20 KXZ46423.1 - 1.3e-126 423.0 0.0 1.8e-126 422.5 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KXZ46423.1 - 1.1e-51 174.4 1.2 2.4e-51 173.4 1.2 1.6 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KXZ46423.1 - 8.4e-22 77.5 0.0 1.6e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KXZ46423.1 - 9.7e-15 55.1 0.1 2.8e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KXZ46423.1 - 4.9e-08 33.1 0.0 2.3e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Toprim domain zf-RING_2 PF13639.6 KXZ46425.1 - 1.5e-05 25.2 3.5 1.5e-05 25.2 3.5 2.6 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXZ46425.1 - 0.00012 22.2 3.4 0.00012 22.2 3.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXZ46425.1 - 0.00015 21.8 0.8 0.00032 20.7 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXZ46425.1 - 0.00016 21.3 2.9 0.00054 19.7 2.0 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXZ46425.1 - 0.0013 18.5 3.2 0.0013 18.5 3.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ46425.1 - 0.0028 17.6 2.1 0.0028 17.6 2.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain XG_FTase PF03254.13 KXZ46426.1 - 3.8e-05 22.5 0.4 0.016 13.8 0.1 2.7 3 0 0 3 3 3 2 Xyloglucan fucosyltransferase DUF5518 PF17647.1 KXZ46427.1 - 0.019 15.1 5.8 0.026 14.7 5.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5518) SAC3_GANP PF03399.16 KXZ46429.1 - 8.8e-18 64.7 0.0 7e-17 61.7 0.0 1.9 1 1 1 2 2 2 1 SAC3/GANP family ERAP1_C PF11838.8 KXZ46429.1 - 0.06 12.9 0.3 0.096 12.2 0.3 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain DASH_Hsk3 PF08227.11 KXZ46429.1 - 0.94 9.9 2.9 12 6.3 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Presenilin PF01080.17 KXZ46430.1 - 6.7 5.4 7.2 9.2 4.9 7.2 1.4 1 0 0 1 1 1 0 Presenilin TMEM237 PF15383.6 KXZ46431.1 - 5.8e-24 84.5 0.0 7.3e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 237 DUF1772 PF08592.11 KXZ46431.1 - 0.53 10.6 4.1 1.9 8.8 4.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) MatE PF01554.18 KXZ46433.1 - 8.5e-37 126.3 22.3 5.8e-25 87.8 9.3 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ46433.1 - 3.8e-07 30.3 0.4 3.8e-07 30.3 0.4 3.8 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 KXZ46433.1 - 0.00016 20.5 2.5 0.00016 20.5 2.5 1.6 2 0 0 2 2 2 1 Lipid II flippase MurJ Lactamase_B_2 PF12706.7 KXZ46435.1 - 1.8e-37 128.8 0.0 2.9e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXZ46435.1 - 6.2e-11 42.5 0.0 1.1e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HSP70 PF00012.20 KXZ46436.1 - 2.9e-07 29.1 0.0 0.093 10.9 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein HCV_capsid PF01543.17 KXZ46437.1 - 0.066 13.4 4.0 0.051 13.8 0.9 2.3 1 1 1 2 2 2 0 Hepatitis C virus capsid protein DUF5427 PF10310.9 KXZ46437.1 - 0.45 9.4 3.8 0.64 8.9 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Sec16_C PF12931.7 KXZ46438.1 - 7.8e-30 104.6 0.0 1.5e-29 103.7 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KXZ46438.1 - 1.4e-11 45.0 0.0 6.8e-11 42.8 0.0 2.3 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Rhodanese PF00581.20 KXZ46439.1 - 3.1e-07 30.9 0.0 5.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_M17 PF00883.21 KXZ46440.1 - 1.3e-49 169.2 0.0 1.8e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KXZ46440.1 - 0.00066 19.5 7.2 0.0017 18.2 0.1 3.5 3 1 1 4 4 4 2 Cytosol aminopeptidase family, N-terminal domain PDZ_6 PF17820.1 KXZ46440.1 - 0.1 12.5 0.0 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Pkinase PF00069.25 KXZ46441.1 - 3.9e-34 118.2 0.0 1.7e-29 103.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46441.1 - 1.1e-30 106.8 0.0 4.5e-27 95.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ46441.1 - 0.027 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ46441.1 - 0.093 12.6 0.0 0.093 12.6 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXZ46441.1 - 0.36 9.7 0.0 0.58 9.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 KXZ46442.1 - 9.8e-31 107.1 0.0 7.6e-29 100.9 0.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46442.1 - 7.3e-28 97.5 0.0 7.8e-19 68.0 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 KXZ46442.1 - 0.018 14.4 0.0 0.057 12.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ46442.1 - 0.034 14.1 1.6 0.1 12.5 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family DHHC PF01529.20 KXZ46443.1 - 9.2e-32 110.0 4.8 9.2e-32 110.0 4.8 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase BT1 PF03092.16 KXZ46444.1 - 5.2e-84 282.4 9.8 3.4e-47 160.9 5.6 2.0 2 0 0 2 2 2 2 BT1 family MFS_1 PF07690.16 KXZ46444.1 - 2.1e-13 49.9 23.7 2e-09 36.8 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TruD PF01142.18 KXZ46445.1 - 5.2e-10 38.7 0.0 0.0035 16.2 0.0 3.1 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) TruD PF01142.18 KXZ46446.1 - 0.0014 17.6 0.0 0.009 14.9 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) SSF PF00474.17 KXZ46447.1 - 4.8e-16 58.6 17.2 1.5e-12 47.1 8.1 2.1 2 0 0 2 2 2 2 Sodium:solute symporter family Chalcone_3 PF16036.5 KXZ46448.1 - 3.3e-07 30.6 0.0 1.8e-06 28.2 0.0 2.5 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 KXZ46448.1 - 3.6e-07 29.8 0.0 2.2e-06 27.2 0.0 1.9 1 1 1 2 2 2 1 Chalcone-flavanone isomerase Chalcone_2 PF16035.5 KXZ46448.1 - 4.9e-05 23.2 0.0 0.0075 16.1 0.1 2.1 1 1 1 2 2 2 2 Chalcone isomerase like ArgJ PF01960.18 KXZ46449.1 - 1.1e-138 462.1 11.8 1.3e-138 461.9 11.8 1.0 1 0 0 1 1 1 1 ArgJ family HSP70 PF00012.20 KXZ46452.1 - 0.015 13.5 0.1 2 6.5 0.1 3.0 2 1 0 2 2 2 0 Hsp70 protein TPR_MLP1_2 PF07926.12 KXZ46453.1 - 0.014 15.5 26.1 0.037 14.1 26.1 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-K PF11802.8 KXZ46453.1 - 0.072 12.7 2.1 0.1 12.1 2.1 1.2 1 0 0 1 1 1 0 Centromere-associated protein K V_ATPase_I PF01496.19 KXZ46453.1 - 1 7.2 2.1 1.4 6.7 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AKNA PF12443.8 KXZ46453.1 - 1.4 9.6 7.8 0.17 12.5 2.5 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor BshC PF10079.9 KXZ46453.1 - 1.8 7.2 7.9 2.5 6.7 7.9 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Snapin_Pallidin PF14712.6 KXZ46453.1 - 5.4 7.5 11.6 0.13 12.7 3.6 2.2 1 1 1 2 2 2 0 Snapin/Pallidin Trns_repr_metal PF02583.17 KXZ46453.1 - 7.1 7.1 10.7 0.51 10.7 3.5 2.8 2 1 1 3 3 3 0 Metal-sensitive transcriptional repressor ISG65-75 PF11727.8 KXZ46453.1 - 8.2 5.6 12.0 3.7 6.7 9.1 1.9 1 1 1 2 2 2 0 Invariant surface glycoprotein CENP-Q PF13094.6 KXZ46454.1 - 0.0005 20.3 6.0 0.00088 19.5 6.0 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.19 KXZ46454.1 - 0.0042 16.9 5.3 0.0069 16.2 5.3 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Laminin_II PF06009.12 KXZ46454.1 - 0.0062 16.5 5.7 0.011 15.8 5.7 1.3 1 0 0 1 1 1 1 Laminin Domain II Uds1 PF15456.6 KXZ46454.1 - 0.05 13.8 11.0 0.11 12.6 11.0 1.5 1 0 0 1 1 1 0 Up-regulated During Septation AAA_13 PF13166.6 KXZ46454.1 - 0.11 11.1 5.1 0.15 10.7 5.1 1.0 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KXZ46454.1 - 0.14 11.0 10.4 0.19 10.5 10.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.12 KXZ46454.1 - 0.15 10.2 7.2 0.2 9.8 7.2 1.1 1 0 0 1 1 1 0 HOOK protein DUF4201 PF13870.6 KXZ46454.1 - 0.4 10.4 7.9 0.61 9.8 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 KXZ46454.1 - 0.42 11.2 3.5 0.57 10.8 2.4 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 KXZ46454.1 - 0.61 9.6 5.6 0.96 8.9 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT57 PF10498.9 KXZ46454.1 - 0.74 8.7 9.0 0.29 10.1 6.5 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 RmuC PF02646.16 KXZ46454.1 - 0.83 8.7 6.7 0.56 9.3 4.9 1.4 1 1 0 1 1 1 0 RmuC family Spectrin PF00435.21 KXZ46454.1 - 1 9.9 10.3 7.1 7.2 9.9 2.3 2 1 1 3 3 3 0 Spectrin repeat HAUS-augmin3 PF14932.6 KXZ46454.1 - 1.6 8.2 11.8 2.4 7.7 11.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CorA PF01544.18 KXZ46454.1 - 1.8 7.8 5.9 2.6 7.3 5.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FH2 PF02181.23 KXZ46454.1 - 1.9 7.5 4.1 1.3 8.0 0.7 1.7 1 1 1 2 2 2 0 Formin Homology 2 Domain CENP-F_leu_zip PF10473.9 KXZ46454.1 - 2 8.4 10.5 6 6.9 10.5 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 KXZ46454.1 - 2.1 8.5 19.6 7 6.8 17.0 2.7 2 1 0 2 2 2 0 TolA binding protein trimerisation HMMR_N PF15905.5 KXZ46454.1 - 2.1 7.8 9.5 3 7.2 9.5 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal T3SSipB PF16535.5 KXZ46454.1 - 2.2 8.7 11.5 4 7.9 11.5 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB Jnk-SapK_ap_N PF09744.9 KXZ46454.1 - 2.9 8.1 12.4 4.5 7.5 12.4 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 KXZ46454.1 - 3.5 6.9 12.5 5.4 6.3 12.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Muted PF14942.6 KXZ46454.1 - 4.2 7.7 7.5 6.9 7.0 7.5 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Occludin_ELL PF07303.13 KXZ46454.1 - 4.6 8.0 8.6 25 5.7 2.8 2.2 1 1 1 2 2 2 0 Occludin homology domain VPS38 PF17649.1 KXZ46454.1 - 6 5.6 5.8 7.6 5.3 5.8 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 APG6_N PF17675.1 KXZ46454.1 - 7.3 7.1 15.1 18 5.8 15.1 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 KXZ46454.1 - 9.3 5.4 6.2 14 4.9 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-MYND PF01753.18 KXZ46456.1 - 4.5e-07 29.8 10.2 4.5e-07 29.8 10.2 1.9 2 0 0 2 2 2 1 MYND finger Sulfotransfer_4 PF17784.1 KXZ46457.1 - 5.7e-67 225.7 0.0 6.7e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ46457.1 - 0.00034 21.1 0.2 0.0011 19.5 0.1 2.1 1 1 1 2 2 2 1 Sulfotransferase family CENP-F_leu_zip PF10473.9 KXZ46458.1 - 8.1e-05 22.7 14.4 0.0019 18.2 6.9 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 KXZ46458.1 - 0.00059 19.9 18.3 0.0028 17.7 6.0 2.2 2 0 0 2 2 2 2 Centrosome localisation domain of PPC89 Filament PF00038.21 KXZ46458.1 - 0.0026 17.4 13.6 0.022 14.4 2.5 2.0 1 1 1 2 2 2 2 Intermediate filament protein Cnn_1N PF07989.11 KXZ46458.1 - 0.0088 16.2 6.9 0.051 13.7 1.6 2.7 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 GAS PF13851.6 KXZ46458.1 - 0.015 14.6 15.0 0.06 12.7 5.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KXZ46458.1 - 0.017 14.6 11.6 0.052 13.0 11.0 1.8 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Ax_dynein_light PF10211.9 KXZ46458.1 - 0.019 14.9 4.6 0.019 14.9 4.6 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain KxDL PF10241.9 KXZ46458.1 - 0.031 14.6 2.0 0.031 14.6 2.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein NPV_P10 PF05531.12 KXZ46458.1 - 0.033 14.7 3.1 0.081 13.4 0.8 2.1 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KXZ46458.1 - 0.044 12.7 15.5 0.084 11.7 6.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KXZ46458.1 - 0.053 13.9 5.6 0.94 9.9 0.3 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) LPP PF04728.13 KXZ46458.1 - 0.085 13.3 9.7 1.7 9.1 1.7 3.0 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Atg14 PF10186.9 KXZ46458.1 - 0.097 11.7 12.9 0.12 11.4 12.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KXZ46458.1 - 0.1 12.6 2.7 0.31 11.1 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Gp58 PF07902.11 KXZ46458.1 - 0.11 10.8 6.0 0.13 10.6 6.0 1.2 1 0 0 1 1 1 0 gp58-like protein ABC_tran_CTD PF16326.5 KXZ46458.1 - 0.13 12.5 20.1 1.6 9.1 1.5 3.1 1 1 3 4 4 4 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 KXZ46458.1 - 0.18 12.0 13.5 4.5 7.4 13.1 2.2 1 1 1 2 2 2 0 Tropomyosin like Exonuc_VII_L PF02601.15 KXZ46458.1 - 0.32 10.5 11.3 0.35 10.4 11.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit NUP50 PF08911.11 KXZ46458.1 - 0.34 11.6 2.4 0.67 10.7 2.3 1.8 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) DUF4407 PF14362.6 KXZ46458.1 - 0.34 10.2 13.1 3.8 6.8 12.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KXZ46458.1 - 0.39 8.6 3.0 0.54 8.1 3.0 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 KXZ46458.1 - 0.42 10.6 11.8 0.94 9.5 0.9 2.9 2 1 1 3 3 3 0 Prefoldin subunit THOC7 PF05615.13 KXZ46458.1 - 0.5 10.6 15.8 0.37 11.1 2.5 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 AAA_13 PF13166.6 KXZ46458.1 - 0.54 8.8 5.8 0.89 8.1 5.8 1.5 1 1 0 1 1 1 0 AAA domain MscS_porin PF12795.7 KXZ46458.1 - 0.71 9.4 26.5 1.8 8.1 26.5 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Prominin PF05478.11 KXZ46458.1 - 0.73 7.7 4.2 0.79 7.6 4.2 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 KXZ46458.1 - 0.97 9.5 14.5 1.9 8.5 6.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mei5 PF10376.9 KXZ46458.1 - 1.3 8.9 9.7 0.43 10.4 5.7 1.8 2 0 0 2 2 2 0 Double-strand recombination repair protein Snapin_Pallidin PF14712.6 KXZ46458.1 - 1.3 9.5 14.1 4.9 7.6 0.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin TolA_bind_tri PF16331.5 KXZ46458.1 - 1.4 9.1 19.2 0.61 10.2 3.9 2.7 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF4763 PF15960.5 KXZ46458.1 - 1.5 8.1 17.7 0.24 10.7 10.6 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) GrpE PF01025.19 KXZ46458.1 - 1.6 8.4 11.5 3.4 7.3 1.2 2.2 1 1 1 2 2 2 0 GrpE Rho_Binding PF08912.11 KXZ46458.1 - 1.7 9.5 12.0 0.49 11.2 2.1 2.9 1 1 2 3 3 3 0 Rho Binding PRKG1_interact PF15898.5 KXZ46458.1 - 1.8 9.5 15.9 2.1e+02 2.9 15.9 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain KELK PF15796.5 KXZ46458.1 - 2 8.9 12.5 1.5 9.3 8.3 2.3 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Baculo_PEP_C PF04513.12 KXZ46458.1 - 2.5 8.2 7.8 1.4 8.9 1.9 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 KXZ46458.1 - 2.8 8.5 6.2 21 5.7 6.1 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.9 KXZ46458.1 - 3.2 8.0 5.7 2.6 8.3 1.1 2.3 2 1 1 3 3 3 0 Haemolysin XhlA FAM184 PF15665.5 KXZ46458.1 - 3.4 7.4 13.6 7.2 6.3 13.6 1.4 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B End3 PF12761.7 KXZ46458.1 - 3.9 7.6 11.0 1.1 9.4 5.0 2.2 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 JIP_LZII PF16471.5 KXZ46458.1 - 4.5 7.5 10.7 5 7.4 1.4 3.3 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Phage_GP20 PF06810.11 KXZ46458.1 - 5.1 6.9 7.4 5.8 6.7 1.9 2.3 1 1 0 2 2 2 0 Phage minor structural protein GP20 SlyX PF04102.12 KXZ46458.1 - 6 7.6 19.2 11 6.7 0.5 3.2 2 1 1 3 3 3 0 SlyX DUF5345 PF17280.2 KXZ46458.1 - 7 6.7 7.4 3.9 7.5 0.0 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5345) OmpH PF03938.14 KXZ46458.1 - 7.3 6.9 14.6 2.4e+02 2.0 14.6 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC2_membrane PF01061.24 KXZ46460.1 - 8.7e-30 103.7 14.4 1.4e-29 103.0 14.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ46460.1 - 3.5e-19 69.7 0.0 5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ46460.1 - 2.9e-06 27.3 0.2 0.046 13.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXZ46460.1 - 0.00088 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KXZ46460.1 - 0.0014 18.3 0.1 0.0034 17.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXZ46460.1 - 0.02 15.1 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXZ46460.1 - 0.074 13.6 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ46460.1 - 0.074 13.4 0.3 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KXZ46460.1 - 0.18 11.5 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ46460.1 - 0.18 12.3 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ46460.1 - 0.29 10.7 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 KXZ46460.1 - 0.97 8.5 11.3 1.5 7.9 11.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein TMF_DNA_bd PF12329.8 KXZ46461.1 - 0.0042 17.1 2.6 0.0042 17.1 2.6 4.1 4 0 0 4 4 4 1 TATA element modulatory factor 1 DNA binding LRR_6 PF13516.6 KXZ46465.1 - 7.9e-29 97.2 8.2 0.0013 18.6 0.2 10.4 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 KXZ46465.1 - 7.3e-08 32.6 0.9 0.041 14.3 0.0 6.3 6 1 2 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ46465.1 - 0.00027 20.7 12.1 2.3 8.1 0.3 7.3 4 2 2 6 6 6 2 Leucine rich repeat TIR_2 PF13676.6 KXZ46465.1 - 0.064 13.9 0.8 0.4 11.3 0.0 2.6 2 1 2 4 4 4 0 TIR domain Amidohydro_1 PF01979.20 KXZ46467.1 - 1.9e-52 178.7 0.0 2.2e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXZ46467.1 - 6.3e-14 52.3 0.4 9.8e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KXZ46467.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase Fez1 PF06818.15 KXZ46468.1 - 0.029 14.8 18.2 0.048 14.1 18.2 1.3 1 0 0 1 1 1 0 Fez1 FliT PF05400.13 KXZ46468.1 - 0.19 12.6 0.5 0.19 12.6 0.5 3.5 2 1 1 3 3 3 0 Flagellar protein FliT Exonuc_VII_L PF02601.15 KXZ46468.1 - 0.28 10.7 11.5 0.41 10.2 11.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DLP_helical PF18709.1 KXZ46468.1 - 1.2 8.2 9.1 0.27 10.4 5.2 1.7 1 1 1 2 2 2 0 Dynamin-like helical domain TFIIA PF03153.13 KXZ46468.1 - 3.7 7.4 18.7 4.9 7.0 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glycolytic PF00274.19 KXZ46469.1 - 6e-143 475.8 0.0 7.6e-143 475.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF5107 PF17128.4 KXZ46469.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5107) SPRY PF00622.28 KXZ46470.1 - 1.8e-23 83.0 0.0 2.4e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KXZ46470.1 - 2.7e-20 72.8 0.0 3.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXZ46470.1 - 0.009 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 LisH Neuralized PF07177.12 KXZ46470.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Neuralized TPR_4 PF07721.14 KXZ46470.1 - 1.8 9.4 6.5 1.8 9.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3685 PF12452.8 KXZ46471.1 - 3.2 7.4 3.6 4.3 7.0 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) UPF0242 PF06785.11 KXZ46472.1 - 0.64 10.1 9.4 1.1 9.3 9.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 KXZ46472.1 - 2.4 7.9 14.7 5.4 6.8 14.7 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KXZ46472.1 - 2.5 7.4 16.1 3.9 6.8 16.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 KXZ46472.1 - 6.5 7.1 8.7 0.36 11.1 1.2 2.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper Pkinase PF00069.25 KXZ46473.1 - 3.3e-30 105.3 0.0 7.9e-27 94.3 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46473.1 - 3.5e-30 105.2 0.0 1.8e-18 66.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KXZ46473.1 - 0.00048 20.1 0.3 0.0018 18.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Herpes_gE PF02480.16 KXZ46473.1 - 0.22 10.3 0.0 0.45 9.2 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DEAD PF00270.29 KXZ46474.1 - 2e-39 135.2 0.0 4.5e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ46474.1 - 1.4e-29 102.6 0.0 1.3e-28 99.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ46474.1 - 4.2e-06 26.9 0.0 7.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXZ46474.1 - 0.024 15.0 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain CMS1 PF14617.6 KXZ46474.1 - 0.024 14.0 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KXZ46474.1 - 0.095 13.0 0.1 0.42 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KXZ46475.1 - 7e-52 175.8 0.0 1e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 KXZ46475.1 - 5.6e-37 126.5 0.0 1.3e-36 125.3 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 KXZ46475.1 - 6.2e-10 39.3 0.1 1.1e-09 38.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ46475.1 - 2.7e-05 24.2 0.0 8e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 KXZ46475.1 - 0.00086 19.4 0.0 0.0028 17.7 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MeaB PF03308.16 KXZ46475.1 - 0.14 11.1 0.6 7.1 5.5 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer2 PF00111.27 KXZ46476.1 - 5.8e-08 32.6 2.1 1.1e-07 31.7 0.5 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Pkinase PF00069.25 KXZ46478.1 - 3.9e-18 65.8 0.0 3.1e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46478.1 - 2.8e-15 56.3 0.0 4.9e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ46478.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase TPR_2 PF07719.17 KXZ46479.1 - 7.2e-07 28.9 3.5 0.012 15.6 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ46479.1 - 2.2e-06 27.2 3.7 0.0089 15.8 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ46479.1 - 1.1e-05 25.2 1.5 0.076 13.3 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ46479.1 - 0.00018 22.1 0.3 1.4 9.6 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ46479.1 - 0.0004 20.8 1.1 0.12 13.0 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ46479.1 - 0.00055 20.4 0.6 0.0024 18.3 0.6 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ46479.1 - 0.00078 19.3 0.1 0.14 12.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ46479.1 - 0.01 16.1 2.1 4.3 7.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ46479.1 - 0.072 13.0 0.6 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 KXZ46479.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.12 KXZ46479.1 - 0.61 10.1 0.1 0.61 10.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps62 PF06101.11 KXZ46481.1 - 1.5e-11 43.4 0.0 2.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Glyco_hydro38C2 PF17677.1 KXZ46482.1 - 1.4e-06 28.3 0.0 3.4e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Ketoacyl-synt_C PF02801.22 KXZ46483.1 - 4e-34 117.1 1.1 2.3e-20 72.8 0.0 2.5 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KXZ46483.1 - 9.7e-23 81.0 3.0 1.2e-17 64.4 0.1 4.3 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain Hydrolase_6 PF13344.6 KXZ46484.1 - 1.1e-30 105.8 0.0 2.4e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ46484.1 - 8.1e-17 61.1 0.0 7.2e-16 58.0 0.0 2.4 3 1 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 KXZ46484.1 - 1.1e-07 32.4 0.0 1.4e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXZ46484.1 - 6.2e-06 26.4 1.2 0.021 14.9 0.0 3.3 3 1 1 4 4 4 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KXZ46484.1 - 0.002 17.8 0.0 0.032 13.9 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 KXZ46484.1 - 0.0045 16.6 0.1 0.29 10.7 0.0 2.2 1 1 1 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.7 KXZ46484.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 KXZ46485.1 - 1.2e-09 37.8 6.3 1.2e-09 37.8 6.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ46485.1 - 1.7e-06 27.8 6.3 1.7e-06 27.8 6.3 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ46485.1 - 3.2e-06 27.1 3.7 3.2e-06 27.1 3.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXZ46485.1 - 3.8e-06 27.1 7.3 3.8e-06 27.1 7.3 2.8 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXZ46485.1 - 4.4e-05 23.2 8.6 4.4e-05 23.2 8.6 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXZ46485.1 - 0.00015 21.7 6.8 0.00015 21.7 6.8 2.8 2 0 0 2 2 2 1 zinc-RING finger domain TackOD1 PF18551.1 KXZ46485.1 - 0.0018 18.0 6.8 0.046 13.4 0.1 2.5 2 0 0 2 2 2 2 Thaumarchaeal output domain 1 zf-C3HC4_2 PF13923.6 KXZ46485.1 - 0.0023 17.8 8.2 0.0023 17.8 8.2 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXZ46485.1 - 0.0083 16.3 5.4 0.0083 16.3 5.4 2.5 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING PSD2 PF07624.11 KXZ46485.1 - 0.098 12.4 0.0 0.44 10.4 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1585) PUF PF00806.19 KXZ46485.1 - 0.13 12.0 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Baculo_IE-1 PF05290.11 KXZ46485.1 - 0.43 10.5 6.9 0.47 10.4 4.9 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF1484 PF07363.11 KXZ46485.1 - 0.5 11.4 4.9 0.15 13.1 1.1 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1484) zf-UDP PF14569.6 KXZ46485.1 - 0.53 10.4 5.9 2.2 8.5 5.9 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger DEC-1_N PF04625.13 KXZ46486.1 - 0.94 8.4 8.3 1.8 7.5 8.3 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4775 PF16001.5 KXZ46486.1 - 1.7 8.0 3.4 2.9 7.2 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) CAP_N PF01213.19 KXZ46486.1 - 2.8 7.4 9.0 5.9 6.3 9.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RRM_1 PF00076.22 KXZ46487.1 - 7.6e-13 48.1 0.0 1.5e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 KXZ46488.1 - 2e-10 41.3 0.0 2.1e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 SET domain Zot PF05707.12 KXZ46493.1 - 3.5e-05 23.5 0.1 0.035 13.7 0.0 2.3 2 0 0 2 2 2 2 Zonular occludens toxin (Zot) Pox_A32 PF04665.12 KXZ46493.1 - 9.7e-05 21.9 0.2 0.0025 17.3 0.0 2.1 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_30 PF13604.6 KXZ46493.1 - 0.028 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ46493.1 - 0.03 14.7 0.0 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXZ46493.1 - 0.11 12.8 0.0 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXZ46493.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4628 PF15429.6 KXZ46496.1 - 0.028 14.1 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DUF1080 PF06439.11 KXZ46499.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) DNA_pol_B_2 PF03175.13 KXZ46501.1 - 1.1e-10 41.1 0.0 8.7e-10 38.0 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Endonuclease_7 PF02945.15 KXZ46501.1 - 2.1e-06 27.5 2.4 2.1e-06 27.5 2.4 2.0 2 0 0 2 2 2 1 Recombination endonuclease VII rve PF00665.26 KXZ46502.1 - 4.5e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain SURF2 PF05477.11 KXZ46502.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Glyco_hydro_42 PF02449.15 KXZ46504.1 - 7.1e-20 71.7 3.0 9.8e-20 71.2 3.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_14 PF01373.17 KXZ46504.1 - 0.082 11.8 1.6 0.32 9.9 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 14 Tom7 PF08038.12 KXZ46506.1 - 4.8e-11 42.1 0.2 6.1e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 TOM7 family ETF_alpha PF00766.19 KXZ46506.1 - 0.17 11.9 0.0 0.19 11.8 0.0 1.0 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain hnRNP_Q_AcD PF18360.1 KXZ46507.1 - 1.9e-48 162.3 1.2 1.6e-12 47.2 0.0 4.1 4 0 0 4 4 4 4 Heterogeneous nuclear ribonucleoprotein Q acidic domain Spore_YpjB PF09577.10 KXZ46507.1 - 0.078 12.8 0.3 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Keratin_2_head PF16208.5 KXZ46507.1 - 0.21 11.7 24.4 0.37 10.9 24.4 1.3 1 0 0 1 1 1 0 Keratin type II head Mito_carr PF00153.27 KXZ46508.1 - 1.3e-53 178.9 5.7 3.7e-18 65.2 0.0 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KXZ46508.1 - 3.9e-11 41.7 2.1 2e-05 23.8 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXZ46508.1 - 4.8e-11 41.7 2.7 3.7e-05 23.3 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KXZ46508.1 - 1.6e-10 41.3 5.7 1.1e-07 32.1 1.2 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ46508.1 - 1.2e-08 34.1 3.2 0.00064 19.1 0.7 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXZ46508.1 - 0.0016 18.3 3.6 0.0096 15.7 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair Ank_2 PF12796.7 KXZ46509.1 - 2.1e-10 41.0 0.1 3e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ46509.1 - 1.2e-07 31.9 0.2 0.0019 18.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXZ46509.1 - 1.3e-06 28.3 0.3 0.0018 18.6 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXZ46509.1 - 7.9e-05 22.9 1.5 0.0014 18.9 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ46509.1 - 0.00016 22.1 0.4 0.016 15.8 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF3915 PF13054.6 KXZ46509.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) TSP_1 PF00090.19 KXZ46510.1 - 0.0001 22.5 7.7 0.0035 17.5 2.5 3.3 2 0 0 2 2 2 2 Thrombospondin type 1 domain Laminin_G_3 PF13385.6 KXZ46510.1 - 0.083 13.0 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KXZ46510.1 - 0.63 10.4 15.9 4.2 7.8 4.2 3.3 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 KXZ46510.1 - 0.82 9.9 22.0 0.0089 16.2 11.0 2.8 2 0 0 2 2 2 0 Laminin EGF domain PPR_2 PF13041.6 KXZ46511.1 - 8.8e-93 304.4 13.2 5.5e-15 55.3 0.0 9.9 3 1 7 10 10 10 8 PPR repeat family PPR PF01535.20 KXZ46511.1 - 1.6e-72 234.8 7.3 1.2e-10 40.9 0.0 10.2 11 0 0 11 11 9 8 PPR repeat PPR_3 PF13812.6 KXZ46511.1 - 3.7e-65 215.9 0.0 2.1e-16 59.8 0.0 6.3 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXZ46511.1 - 2.3e-64 212.7 0.1 1.2e-08 34.5 0.0 10.6 11 0 0 11 11 10 8 PPR repeat PPR_long PF17177.4 KXZ46511.1 - 7.4e-35 120.2 0.5 2.4e-20 72.8 0.7 2.8 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KXZ46511.1 - 2.5e-12 47.1 1.5 0.0058 17.1 0.0 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ46511.1 - 4.2e-11 42.1 0.6 3.4 7.9 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ46511.1 - 4.6e-11 42.6 8.4 0.8 10.7 0.0 9.6 7 2 4 11 11 9 2 Tetratricopeptide repeat MRP-S27 PF10037.9 KXZ46511.1 - 1.6e-08 33.9 0.0 0.13 11.1 0.0 3.9 1 1 3 4 4 4 3 Mitochondrial 28S ribosomal protein S27 TPR_1 PF00515.28 KXZ46511.1 - 2.3e-08 33.5 0.2 5.6 7.0 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat Cyclin_N PF00134.23 KXZ46511.1 - 2.5e-08 33.7 0.0 6.6e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Clathrin PF00637.20 KXZ46511.1 - 6.8e-08 32.5 0.0 0.00026 20.9 0.0 4.3 2 1 0 3 3 3 1 Region in Clathrin and VPS TPR_12 PF13424.6 KXZ46511.1 - 1e-05 25.7 1.2 1.6 9.1 0.0 5.9 3 1 3 6 6 6 2 Tetratricopeptide repeat PYRIN PF02758.16 KXZ46511.1 - 0.00017 21.7 1.1 4.4 7.5 0.0 5.3 5 1 1 6 6 5 1 PAAD/DAPIN/Pyrin domain TPR_6 PF13174.6 KXZ46511.1 - 0.0003 21.2 3.4 5.4 7.9 0.2 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat Cyclin_C PF02984.19 KXZ46511.1 - 0.00036 20.6 0.1 0.0025 17.9 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain TPR_2 PF07719.17 KXZ46511.1 - 0.00044 20.2 13.6 20 5.6 0.0 8.0 9 0 0 9 9 7 0 Tetratricopeptide repeat Ank_5 PF13857.6 KXZ46511.1 - 0.00055 20.2 0.2 1.3 9.4 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) TPR_16 PF13432.6 KXZ46511.1 - 0.0012 19.4 0.0 14 6.5 0.0 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ46511.1 - 0.0026 17.0 0.0 0.16 11.1 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Vps39_1 PF10366.9 KXZ46511.1 - 0.003 17.8 0.1 10 6.5 0.0 4.7 2 1 3 5 5 5 0 Vacuolar sorting protein 39 domain 1 ATP13 PF12921.7 KXZ46511.1 - 0.0045 16.8 0.0 0.68 9.8 0.0 4.0 4 1 0 4 4 4 1 Mitochondrial ATPase expression BTAD PF03704.17 KXZ46511.1 - 0.0054 17.2 0.3 11 6.5 0.0 4.4 3 1 1 4 4 3 0 Bacterial transcriptional activator domain ECSIT PF06239.11 KXZ46511.1 - 0.015 14.4 0.0 17 4.5 0.0 3.7 2 1 1 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway BKACE PF05853.12 KXZ46511.1 - 0.031 13.6 0.3 5.5 6.2 0.0 2.8 2 1 0 2 2 2 0 beta-keto acid cleavage enzyme IlvC PF01450.19 KXZ46511.1 - 0.034 14.4 0.1 18 5.6 0.0 3.3 3 1 1 4 4 4 0 Acetohydroxy acid isomeroreductase, catalytic domain FAT PF02259.23 KXZ46511.1 - 0.091 12.0 1.4 5.1 6.2 0.0 2.8 1 1 1 2 2 2 0 FAT domain HrpB1_HrpK PF09613.10 KXZ46511.1 - 0.12 12.0 3.9 0.85 9.3 0.0 3.7 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) ATC_hydrolase PF14196.6 KXZ46511.1 - 0.23 12.2 1.6 12 6.6 0.1 2.9 3 0 0 3 3 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase TPR_8 PF13181.6 KXZ46511.1 - 8.6 6.9 6.4 54 4.4 0.0 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat ATP11 PF06644.11 KXZ46512.1 - 1.3e-31 110.4 0.0 1.5e-31 110.2 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein DUF383 PF04063.14 KXZ46514.1 - 4.3e-19 68.9 0.0 9.8e-19 67.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KXZ46514.1 - 2.5e-05 24.1 0.0 7.7e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_EZ PF13513.6 KXZ46514.1 - 0.089 13.3 5.3 2.5 8.7 0.0 3.5 4 0 0 4 4 4 0 HEAT-like repeat SKI PF01202.22 KXZ46516.1 - 3.7e-38 131.1 0.0 7.7e-38 130.1 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KXZ46516.1 - 2.4e-08 34.6 0.0 8.2e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 KXZ46516.1 - 6.2e-06 26.5 0.0 1.6e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 KXZ46516.1 - 0.00065 19.5 0.2 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase AAA_33 PF13671.6 KXZ46516.1 - 0.00094 19.4 1.1 0.004 17.3 0.0 2.5 3 1 0 3 3 2 1 AAA domain APS_kinase PF01583.20 KXZ46516.1 - 0.0012 18.8 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 KXZ46516.1 - 0.0018 18.7 0.1 0.0059 17.0 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KXZ46516.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ46516.1 - 0.014 15.4 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KXZ46516.1 - 0.023 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) dNK PF01712.19 KXZ46516.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA PF00004.29 KXZ46516.1 - 0.038 14.4 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KXZ46516.1 - 0.041 14.3 0.1 0.14 12.6 0.0 2.0 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.22 KXZ46516.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CoaE PF01121.20 KXZ46516.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase NB-ARC PF00931.22 KXZ46516.1 - 0.074 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 KXZ46516.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KXZ46516.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXZ46516.1 - 0.14 12.4 0.0 0.53 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 KXZ46516.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_29 PF13555.6 KXZ46516.1 - 0.18 11.6 0.7 0.36 10.6 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain 1-cysPrx_C PF10417.9 KXZ46518.1 - 5e-05 23.1 3.0 11 5.9 0.0 4.9 5 0 0 5 5 5 2 C-terminal domain of 1-Cys peroxiredoxin Unstab_antitox PF09720.10 KXZ46518.1 - 0.029 14.4 4.4 21 5.2 0.1 4.2 4 1 1 5 5 5 0 Putative addiction module component MBD PF01429.19 KXZ46518.1 - 0.049 13.3 4.8 10 5.9 0.0 4.0 3 1 1 4 4 4 0 Methyl-CpG binding domain T4SS PF07996.11 KXZ46518.1 - 4.5 7.6 5.0 26 5.2 0.1 2.9 2 1 0 2 2 2 0 Type IV secretion system proteins Tox-GHH PF15636.6 KXZ46518.1 - 9 6.4 6.9 20 5.3 0.2 3.5 3 1 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin SurE PF01975.17 KXZ46519.1 - 9.9e-50 169.0 0.5 1.5e-49 168.5 0.5 1.2 1 0 0 1 1 1 1 Survival protein SurE RsgA_GTPase PF03193.16 KXZ46521.1 - 3.7e-46 157.1 0.0 6.9e-35 120.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXZ46521.1 - 0.0073 16.4 0.1 0.18 11.9 0.0 2.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase Ras PF00071.22 KXZ46521.1 - 0.022 14.3 0.0 0.31 10.6 0.0 2.0 1 1 1 2 2 2 0 Ras family AAA_16 PF13191.6 KXZ46521.1 - 0.032 14.6 0.5 0.13 12.6 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KXZ46521.1 - 0.039 13.7 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KXZ46521.1 - 0.04 13.4 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain IIGP PF05049.13 KXZ46521.1 - 0.04 13.0 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 KXZ46521.1 - 0.05 13.2 0.0 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 KXZ46521.1 - 0.051 13.2 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KXZ46521.1 - 0.054 14.0 0.0 0.093 13.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXZ46521.1 - 0.068 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXZ46521.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXZ46521.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KXZ46522.1 - 1.8e-29 102.7 0.0 2.6e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ46522.1 - 2e-19 70.0 0.0 8.5e-19 67.9 0.0 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ46522.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Tho2 PF11262.8 KXZ46523.1 - 0.11 11.6 7.6 0.26 10.5 7.6 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ATP12 PF07542.11 KXZ46524.1 - 2.8e-28 98.5 0.0 4.5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Ribosomal_S14 PF00253.21 KXZ46525.1 - 6.4e-20 70.7 0.2 2.4e-19 68.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DUF92 PF01940.16 KXZ46526.1 - 2.4e-72 243.2 8.4 2.4e-72 243.2 8.4 3.4 2 1 0 2 2 2 1 Integral membrane protein DUF92 TRAM_LAG1_CLN8 PF03798.16 KXZ46527.1 - 2.8e-29 102.3 17.0 3.1e-29 102.1 17.0 1.0 1 0 0 1 1 1 1 TLC domain DUF751 PF05421.11 KXZ46528.1 - 3.9e-18 65.9 3.0 5.2e-18 65.5 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF751) DUF4282 PF14110.6 KXZ46528.1 - 0.04 14.6 0.2 0.052 14.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) AAA_16 PF13191.6 KXZ46529.1 - 1.2e-11 45.3 3.0 1.4e-11 45.0 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain ORC4_C PF14629.6 KXZ46529.1 - 2.4e-11 43.4 0.0 4.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_22 PF13401.6 KXZ46529.1 - 1.8e-09 38.0 0.1 5.3e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ46529.1 - 5.4e-07 30.1 0.1 1.2e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXZ46529.1 - 2.3e-05 24.8 0.7 0.00027 21.3 0.7 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXZ46529.1 - 0.0047 16.7 0.7 0.0047 16.7 0.7 2.8 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KXZ46529.1 - 0.0091 15.4 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KXZ46529.1 - 0.0099 15.8 0.1 0.029 14.3 0.1 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KXZ46529.1 - 0.021 14.3 0.1 0.053 13.0 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KXZ46529.1 - 0.028 14.4 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 KXZ46529.1 - 0.033 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXZ46529.1 - 0.043 13.8 0.1 0.11 12.5 0.1 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KXZ46529.1 - 0.053 12.8 0.2 0.14 11.4 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KXZ46529.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DEAD PF00270.29 KXZ46529.1 - 0.064 13.0 0.8 0.53 10.0 0.8 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase TniB PF05621.11 KXZ46529.1 - 0.084 12.3 0.0 1.6 8.1 0.0 2.2 1 1 0 1 1 1 0 Bacterial TniB protein T2SSE PF00437.20 KXZ46529.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KXZ46529.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.5 1 1 0 1 1 1 0 KaiC RNA_helicase PF00910.22 KXZ46529.1 - 0.24 11.8 0.1 7.6 7.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KXZ46529.1 - 0.32 11.2 2.2 2.4 8.3 1.0 2.7 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KXZ46529.1 - 2.2 7.7 5.1 0.62 9.5 1.4 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain CNOT11 PF10155.9 KXZ46530.1 - 5e-46 155.9 1.6 7.4e-46 155.4 1.6 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 DAHP_synth_2 PF01474.16 KXZ46531.1 - 1.6e-192 639.8 0.0 1.9e-192 639.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family YHYH PF14240.6 KXZ46532.1 - 2.4e-10 40.7 13.1 4.3e-10 39.9 0.7 2.8 1 1 2 3 3 3 2 YHYH protein RCDG1 PF15725.5 KXZ46532.1 - 3.7 8.1 7.4 7.8 7.0 7.4 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DnaB_C PF03796.15 KXZ46533.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain WD40_alt PF14077.6 KXZ46533.1 - 0.16 11.8 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif TPT PF03151.16 KXZ46534.1 - 6.4e-17 61.8 21.5 7.9e-17 61.5 21.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ46534.1 - 1.7e-06 28.2 28.0 0.00015 21.9 7.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family zf-MYND PF01753.18 KXZ46535.1 - 5.1e-06 26.5 12.9 5.1e-06 26.5 12.9 2.0 2 0 0 2 2 2 1 MYND finger Ank_4 PF13637.6 KXZ46536.1 - 7e-13 48.8 1.3 0.01 16.4 0.2 5.7 3 3 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ46536.1 - 4.2e-07 30.5 0.0 0.096 13.3 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ46536.1 - 1.7e-06 27.9 0.6 6.4 7.7 0.0 5.7 5 1 1 6 6 6 2 Ankyrin repeat LRV PF01816.17 KXZ46536.1 - 7.8 7.1 7.2 1.5 9.4 1.6 2.8 3 0 0 3 3 3 0 Leucine rich repeat variant CENP-T_C PF15511.6 KXZ46537.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46537.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ46537.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ46537.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46537.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ46537.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ46537.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated U-box PF04564.15 KXZ46538.1 - 5.8e-24 84.1 0.0 1.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.6 KXZ46538.1 - 5.1e-09 35.7 0.1 1.7e-07 30.8 0.0 3.1 3 1 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 KXZ46538.1 - 3.3e-08 33.0 6.1 0.00021 21.1 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ46538.1 - 9.4e-08 31.6 1.0 0.00092 18.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ46538.1 - 0.0001 22.2 0.2 0.12 12.7 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ46538.1 - 0.00015 22.0 12.8 0.24 11.7 0.0 4.0 2 2 1 4 4 4 2 Tetratricopeptide repeat zf-Nse PF11789.8 KXZ46538.1 - 0.00029 20.6 0.0 0.00087 19.1 0.0 1.7 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_17 PF13431.6 KXZ46538.1 - 0.0011 19.1 0.2 0.084 13.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 KXZ46538.1 - 0.0035 17.5 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_7 PF13176.6 KXZ46538.1 - 0.027 14.5 3.8 0.45 10.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ46538.1 - 0.34 11.8 16.4 2.5 9.1 0.0 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ46538.1 - 0.37 10.7 10.4 1.6 8.7 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ46538.1 - 3.6 8.3 13.1 4.9 7.9 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat FeS_assembly_P PF01883.19 KXZ46539.1 - 4.6e-16 58.7 0.1 8.6e-16 57.9 0.0 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CENP-T_C PF15511.6 KXZ46540.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46540.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ46540.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ46540.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46540.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ46540.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ46540.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ46541.1 - 2e-40 138.2 1.7 2.2e-40 138.1 1.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ46541.1 - 5.1e-05 23.6 0.0 7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ46541.1 - 0.00017 21.6 0.1 0.0002 21.4 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ46541.1 - 0.002 18.4 0.1 0.0028 17.9 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ46541.1 - 0.0043 17.1 0.0 0.0055 16.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KXZ46542.1 - 1.3e-09 38.5 0.0 1.6e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KXZ46542.1 - 0.08 13.4 0.1 0.13 12.7 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KXZ46542.1 - 0.089 13.1 0.3 0.16 12.3 0.1 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L4 PF00573.22 KXZ46544.1 - 1.9e-53 181.1 0.8 2.6e-53 180.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Histone_H2A_C PF16211.5 KXZ46545.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ46545.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46545.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46546.1 - 6e-21 75.2 7.7 9.1e-21 74.6 7.7 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46546.1 - 2.5e-05 24.5 0.1 8.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ46546.1 - 0.0019 18.6 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ46546.1 - 0.025 14.6 5.7 0.049 13.7 5.6 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ46546.1 - 0.027 14.1 0.6 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ46546.1 - 1.2 9.7 8.7 3.2 8.3 8.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 KXZ46546.1 - 5.1 6.8 10.4 6.8 6.4 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Histone PF00125.24 KXZ46547.1 - 3.1e-47 160.2 0.7 3.7e-47 160.0 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ46547.1 - 7.7e-05 23.0 0.0 0.00011 22.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ46547.1 - 0.00024 21.2 0.1 0.00031 20.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ46547.1 - 0.003 17.8 0.1 0.0042 17.3 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ46547.1 - 0.006 16.7 0.0 0.0082 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KXZ46548.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46548.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ46548.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ46548.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46548.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ46548.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ46548.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated MSP1_C PF07462.11 KXZ46549.1 - 0.0036 16.1 0.9 0.0049 15.6 0.9 1.3 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus KASH_CCD PF14662.6 KXZ46549.1 - 0.049 13.5 5.6 0.074 12.9 5.6 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Pro_isomerase PF00160.21 KXZ46550.1 - 3.3e-43 147.7 0.0 6.2e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KXZ46550.1 - 3.8e-15 55.5 0.1 6.4e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.20 KXZ46550.1 - 1.4e-05 25.0 0.0 0.00019 21.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Sporozoite_P67 PF05642.11 KXZ46550.1 - 0.069 11.2 1.8 0.16 10.0 1.8 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Thioredoxin_2 PF13098.6 KXZ46550.1 - 0.088 13.3 0.1 0.61 10.6 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain SRP54 PF00448.22 KXZ46551.1 - 7.7e-26 90.9 1.1 1.5e-17 63.9 0.4 2.7 2 1 1 3 3 3 2 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KXZ46551.1 - 1.2e-22 80.4 2.0 1.7e-22 79.9 1.0 1.8 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 KXZ46551.1 - 3.9e-12 46.2 1.3 1.4e-11 44.4 0.4 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 KXZ46551.1 - 1.3e-05 25.2 0.0 4.3e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KXZ46551.1 - 0.00049 19.4 3.6 0.004 16.4 0.1 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase Ehrlichia_rpt PF09528.10 KXZ46551.1 - 0.0017 17.8 0.2 0.0058 16.1 0.0 2.1 3 0 0 3 3 3 1 Ehrlichia tandem repeat (Ehrlichia_rpt) AAA_31 PF13614.6 KXZ46551.1 - 0.0049 16.8 0.9 0.009 15.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXZ46551.1 - 0.0093 15.3 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin ParA PF10609.9 KXZ46551.1 - 0.027 13.9 0.2 0.065 12.7 0.2 1.7 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase TPP_enzyme_M PF00205.22 KXZ46551.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain 3HCDH PF00725.22 KXZ46551.1 - 0.11 13.1 0.5 1.3 9.7 0.0 3.0 4 1 1 5 5 5 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TSC22 PF01166.18 KXZ46552.1 - 0.019 15.3 0.9 0.062 13.6 0.9 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KXZ46552.1 - 0.044 13.9 16.8 0.11 12.6 0.6 2.5 2 0 0 2 2 2 0 bZIP transcription factor zf-HC5HC2H PF13771.6 KXZ46552.1 - 0.057 13.7 0.5 0.12 12.6 0.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF1198 PF06711.11 KXZ46552.1 - 0.15 12.2 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Herpes_UL6 PF01763.16 KXZ46552.1 - 0.74 8.3 4.6 1.2 7.6 2.2 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like Sel1 PF08238.12 KXZ46554.1 - 0.0033 18.0 0.8 0.0033 18.0 0.8 6.8 7 1 0 7 7 7 2 Sel1 repeat Nre_C PF04895.12 KXZ46555.1 - 0.0062 16.4 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 Archaeal Nre, C-terminal TPR_16 PF13432.6 KXZ46556.1 - 0.088 13.5 2.5 0.088 13.5 2.5 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ46556.1 - 0.13 12.2 1.0 0.2 11.5 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M11 PF05548.11 KXZ46557.1 - 4.3e-15 55.7 0.0 9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Gametolysin peptidase M11 EGF PF00008.27 KXZ46557.1 - 4.3 7.7 19.9 3.1 8.2 5.2 3.1 2 0 0 2 2 2 0 EGF-like domain Ank_4 PF13637.6 KXZ46558.1 - 0.0039 17.7 1.1 0.05 14.2 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) FAM184 PF15665.5 KXZ46559.1 - 0.00079 19.3 28.2 0.00079 19.3 28.2 7.9 4 3 4 8 8 8 3 Family with sequence similarity 184, A and B DUF1664 PF07889.12 KXZ46559.1 - 0.0062 16.6 0.5 0.0062 16.6 0.5 7.5 7 3 0 7 7 7 1 Protein of unknown function (DUF1664) SlyX PF04102.12 KXZ46559.1 - 0.012 16.2 0.2 0.012 16.2 0.2 15.3 9 3 9 19 19 19 0 SlyX YojJ PF10372.9 KXZ46559.1 - 0.12 12.5 2.2 13 6.0 0.0 4.6 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus Cnn_1N PF07989.11 KXZ46559.1 - 1.8 8.8 0.0 1.8 8.8 0.0 9.9 11 2 0 11 11 11 0 Centrosomin N-terminal motif 1 adh_short PF00106.25 KXZ46560.1 - 4.3e-13 49.1 0.0 8.8e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ46560.1 - 2.7e-05 23.9 0.0 5.7e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ46560.1 - 0.0052 16.7 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 KR domain HAD PF12710.7 KXZ46561.1 - 0.16 12.4 2.1 0.35 11.2 1.8 1.6 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase WSC PF01822.19 KXZ46562.1 - 1.2e-07 31.8 0.4 1.8e-07 31.2 0.4 1.3 1 0 0 1 1 1 1 WSC domain Mito_fiss_reg PF05308.11 KXZ46562.1 - 0.98 9.4 6.3 5.7 6.9 2.4 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Nucleotid_trans PF03407.16 KXZ46564.1 - 1.5e-33 116.6 0.1 2.5e-33 115.9 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase HMG_box PF00505.19 KXZ46565.1 - 3e-19 69.2 4.4 4.6e-19 68.6 4.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXZ46565.1 - 2.5e-11 44.0 5.1 3.5e-11 43.5 5.1 1.4 1 1 0 1 1 1 1 HMG-box domain F420H2_quin_red PF04075.14 KXZ46565.1 - 0.063 13.4 0.3 0.081 13.1 0.3 1.1 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase SLATT_6 PF18169.1 KXZ46565.1 - 0.16 11.6 1.5 0.16 11.6 1.5 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 FTCD_C PF04961.12 KXZ46565.1 - 0.18 11.6 4.5 0.18 11.5 4.5 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Peptidase_S49_N PF08496.10 KXZ46565.1 - 4.7 7.3 9.4 5.3 7.1 9.4 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Fcf1 PF04900.12 KXZ46567.1 - 6.8e-13 48.9 0.0 2.4e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Fcf1 Asparaginase_2 PF01112.18 KXZ46568.1 - 1.5e-18 66.9 4.9 1.7e-18 66.7 4.9 1.0 1 0 0 1 1 1 1 Asparaginase Asparaginase_2 PF01112.18 KXZ46569.1 - 1.8e-08 33.8 15.1 1.2e-07 31.1 15.1 2.0 1 1 0 1 1 1 1 Asparaginase Glyoxal_oxid_N PF07250.11 KXZ46572.1 - 1.6e-17 63.5 0.0 2.4e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 KXZ46572.1 - 3.5e-05 23.6 0.6 1.1 9.3 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 KXZ46572.1 - 0.001 19.2 0.3 5.4 7.5 0.0 4.6 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.6 KXZ46572.1 - 0.052 13.6 2.5 4.5 7.4 0.0 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain DUF5122 PF17164.4 KXZ46572.1 - 0.34 11.2 6.7 8.1 6.8 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller RRM_1 PF00076.22 KXZ46573.1 - 1e-13 50.9 0.0 4.5e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.18 KXZ46574.1 - 1.6e-31 109.7 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PDH_E1_M PF17831.1 KXZ46574.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain Surp PF01805.20 KXZ46575.1 - 7.5e-31 105.9 3.7 3.2e-15 55.8 0.1 3.0 3 0 0 3 3 3 2 Surp module Pkinase PF00069.25 KXZ46576.1 - 3.6e-38 131.5 0.0 4.1e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46576.1 - 8.7e-23 80.9 0.0 1e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46576.1 - 8.4e-05 22.0 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like YqfQ PF14181.6 KXZ46576.1 - 0.47 10.6 2.2 0.6 10.3 2.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein Gluconate_2-dh3 PF13618.6 KXZ46577.1 - 0.11 12.7 0.6 0.13 12.5 0.6 1.2 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 CotJB PF12652.7 KXZ46577.1 - 0.17 12.1 1.7 0.15 12.3 0.7 1.4 2 0 0 2 2 2 0 CotJB protein Matrilin_ccoil PF10393.9 KXZ46577.1 - 0.45 10.4 3.4 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF615 PF04751.14 KXZ46578.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF615) AAA_30 PF13604.6 KXZ46578.1 - 0.027 14.2 0.0 0.075 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXZ46578.1 - 0.12 12.0 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KXZ46578.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-RanBP PF00641.18 KXZ46580.1 - 0.07 12.5 0.3 0.15 11.4 0.3 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PHD PF00628.29 KXZ46580.1 - 0.1 12.5 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.25 KXZ46581.1 - 4.9e-48 163.8 0.0 6.2e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46581.1 - 3.9e-31 108.3 0.0 4.8e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46581.1 - 1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like HTH_29 PF13551.6 KXZ46581.1 - 0.0053 16.8 0.0 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix APH PF01636.23 KXZ46581.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Histone_H2A_C PF16211.5 KXZ46582.1 - 5e-19 67.8 2.2 1e-18 66.7 2.2 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ46582.1 - 6.6e-19 68.6 0.0 1.4e-16 61.0 0.0 2.2 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46582.1 - 1.5e-05 25.2 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46583.1 - 5.4e-22 78.6 4.9 7.5e-22 78.1 4.9 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46583.1 - 2.6e-05 24.4 0.1 8.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ46583.1 - 0.0019 18.6 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ46583.1 - 0.023 14.4 0.2 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ46583.1 - 0.047 13.7 6.6 0.11 12.6 6.6 1.6 1 1 0 1 1 1 0 YscO-like protein DUF3391 PF11871.8 KXZ46583.1 - 1.6 9.3 8.8 3.8 8.1 8.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 KXZ46583.1 - 4.5 7.0 10.5 6 6.6 10.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Red1 PF07964.11 KXZ46583.1 - 8 4.6 11.9 10 4.2 11.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Histone PF00125.24 KXZ46584.1 - 4.3e-36 124.2 1.2 4.6e-36 124.1 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXZ46584.1 - 0.0009 19.3 0.1 0.0011 19.1 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46584.1 - 0.0014 19.0 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXZ46584.1 - 0.0018 18.5 0.1 0.0023 18.2 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ46584.1 - 0.024 14.7 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KXZ46585.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46585.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ46585.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ46585.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46585.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ46585.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ46585.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated RRM_1 PF00076.22 KXZ46586.1 - 5.6e-12 45.3 0.0 1.4e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KXZ46587.1 - 7.9e-40 136.9 0.0 9.7e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46587.1 - 3.1e-18 66.0 0.0 7.3e-14 51.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ46587.1 - 0.00067 18.5 0.0 0.0097 14.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXZ46587.1 - 0.08 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Histone PF00125.24 KXZ46588.1 - 5.4e-22 78.6 4.9 7.5e-22 78.1 4.9 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46588.1 - 2.6e-05 24.4 0.1 8.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ46588.1 - 0.0019 18.6 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ46588.1 - 0.023 14.4 0.2 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ46588.1 - 0.047 13.7 6.6 0.11 12.6 6.6 1.6 1 1 0 1 1 1 0 YscO-like protein DUF3391 PF11871.8 KXZ46588.1 - 1.6 9.3 8.8 3.8 8.1 8.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 KXZ46588.1 - 4.5 7.0 10.5 6 6.6 10.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Red1 PF07964.11 KXZ46588.1 - 8 4.6 11.9 10 4.2 11.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Histone PF00125.24 KXZ46589.1 - 1.1e-29 103.4 0.0 3.2e-16 59.9 0.0 2.1 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KXZ46589.1 - 5.9e-19 67.5 2.2 1.2e-18 66.5 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KXZ46589.1 - 1.6e-09 37.9 0.0 0.00014 22.0 0.0 2.3 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HlyD_D4 PF16572.5 KXZ46590.1 - 0.014 15.2 1.1 0.03 14.2 1.1 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB NAD_binding_1 PF00175.21 KXZ46591.1 - 8.3e-27 94.0 0.0 1.5e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXZ46591.1 - 0.0074 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_1 PF00667.20 KXZ46591.1 - 0.039 13.5 0.0 9.1 5.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Fasciclin PF02469.22 KXZ46592.1 - 3.1e-76 253.7 1.3 2.5e-12 47.1 0.0 6.4 6 0 0 6 6 6 6 Fasciclin domain DMA PF03474.14 KXZ46592.1 - 0.0023 17.5 0.6 6.5 6.4 0.0 3.6 3 0 0 3 3 3 2 DMRTA motif DUF3160 PF11369.8 KXZ46592.1 - 0.061 11.8 0.0 11 4.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3160) Hexapep_loop PF18776.1 KXZ46592.1 - 0.074 12.7 0.2 1.1e+02 2.6 0.0 3.8 3 0 0 3 3 3 0 Hexapeptide repeat including loop YbbR PF07949.12 KXZ46592.1 - 0.39 11.1 6.6 39 4.7 0.1 3.6 3 0 0 3 3 3 0 YbbR-like protein Attacin_C PF03769.15 KXZ46592.1 - 0.49 10.6 4.1 24 5.2 0.1 3.4 3 0 0 3 3 3 0 Attacin, C-terminal region STN PF07660.14 KXZ46592.1 - 1.8 8.4 5.1 12 5.8 0.1 3.7 3 0 0 3 3 3 0 Secretin and TonB N terminus short domain Pkinase PF00069.25 KXZ46593.1 - 4e-43 147.7 0.0 5.3e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46593.1 - 4.8e-14 52.3 0.0 7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ46593.1 - 0.23 10.2 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CobT PF06213.12 KXZ46594.1 - 6.1 6.1 16.7 8.8 5.6 16.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NAD_binding_1 PF00175.21 KXZ46595.1 - 8.2e-29 100.5 0.0 1.7e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXZ46595.1 - 2.4e-22 79.1 0.0 4.3e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXZ46595.1 - 3.8e-05 23.8 0.0 0.005 17.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAP PF07174.11 KXZ46595.1 - 0.015 14.8 0.3 0.027 13.9 0.3 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) FAD_binding_9 PF08021.11 KXZ46595.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain adh_short PF00106.25 KXZ46596.1 - 1.7e-42 145.1 0.0 2.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ46596.1 - 2.7e-29 102.4 1.0 3.5e-29 102.0 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ46596.1 - 4.4e-09 36.5 0.2 6.6e-09 35.9 0.2 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KXZ46596.1 - 1.8e-05 24.7 0.9 0.0019 18.2 0.1 2.7 1 1 2 3 3 3 2 Zinc-binding dehydrogenase CTD_bind PF04818.13 KXZ46598.1 - 1.7e-16 60.8 0.2 8.5e-16 58.5 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 KXZ46598.1 - 0.00012 22.0 0.1 0.00055 19.9 0.0 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 AAA_23 PF13476.6 KXZ46598.1 - 0.0021 18.6 5.8 0.0032 18.0 5.8 1.3 1 0 0 1 1 1 1 AAA domain SOBP PF15279.6 KXZ46598.1 - 0.018 15.6 8.9 0.033 14.8 8.9 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Rrn6 PF10214.9 KXZ46598.1 - 0.027 13.0 12.5 0.036 12.6 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DDHD PF02862.17 KXZ46598.1 - 0.065 13.4 6.2 0.11 12.7 6.2 1.4 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 KXZ46598.1 - 0.12 10.3 14.5 0.17 9.8 14.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 KXZ46598.1 - 0.19 11.2 12.6 0.26 10.8 12.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Velvet PF11754.8 KXZ46598.1 - 0.37 10.7 7.5 0.56 10.1 7.5 1.4 1 0 0 1 1 1 0 Velvet factor Paf1 PF03985.13 KXZ46598.1 - 0.41 9.6 15.8 0.59 9.1 15.8 1.3 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 KXZ46598.1 - 0.42 10.4 14.5 0.62 9.8 14.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Exonuc_VII_L PF02601.15 KXZ46598.1 - 0.54 9.8 13.5 0.97 8.9 13.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0565 PF10561.9 KXZ46598.1 - 0.56 9.4 4.0 0.78 8.9 4.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Rtf2 PF04641.12 KXZ46598.1 - 0.59 9.5 13.0 2.9 7.2 12.9 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger UPF0560 PF10577.9 KXZ46598.1 - 0.9 8.0 13.9 1.2 7.5 13.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 eIF-3_zeta PF05091.12 KXZ46598.1 - 1 8.2 14.8 1.5 7.7 14.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 KXZ46598.1 - 1.1 8.0 15.8 1.5 7.5 15.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 KXZ46598.1 - 2.2 7.8 17.5 3.4 7.2 17.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Suf PF05843.14 KXZ46598.1 - 2.4 8.1 15.7 1.8 8.5 14.1 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MRP-S26 PF14943.6 KXZ46598.1 - 3.4 7.6 20.0 5.4 6.9 20.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PAT1 PF09770.9 KXZ46598.1 - 4.8 5.3 21.8 6.1 5.0 21.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 KXZ46598.1 - 5.6 5.5 7.6 7.3 5.1 7.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Asp-B-Hydro_N PF05279.11 KXZ46598.1 - 6 6.9 14.7 8.5 6.4 14.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CENP-T_C PF15511.6 KXZ46599.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46599.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ46599.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ46599.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46599.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ46599.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ46599.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Es2 PF09751.9 KXZ46600.1 - 4.4e-69 234.3 0.0 8.2e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein Es2 ParcG PF10274.9 KXZ46601.1 - 6e-19 68.9 0.0 1.3e-18 67.8 0.0 1.4 2 0 0 2 2 2 1 Parkin co-regulated protein MCD_N PF17408.2 KXZ46602.1 - 0.032 14.4 0.3 0.075 13.2 0.1 1.7 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain PCNA_C PF02747.15 KXZ46602.1 - 0.044 13.9 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain Sec20 PF03908.13 KXZ46602.1 - 0.088 12.7 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Sec20 Cytochrome_CBB3 PF13442.6 KXZ46603.1 - 7.6e-17 61.4 0.1 1.3e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KXZ46603.1 - 2e-08 35.3 1.2 9.1e-08 33.1 1.1 2.0 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 KXZ46603.1 - 5.9e-06 26.0 0.3 0.00017 21.3 0.0 2.1 1 1 1 2 2 2 1 Cytochrome c-550 domain Cytochrome_CBB3 PF13442.6 KXZ46604.1 - 7.6e-17 61.4 0.1 1.3e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KXZ46604.1 - 1.9e-08 35.3 1.2 8.8e-08 33.2 1.0 2.0 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 KXZ46604.1 - 6.7e-06 25.9 0.3 0.00017 21.3 0.0 2.1 1 1 1 2 2 2 1 Cytochrome c-550 domain DUF4813 PF16072.5 KXZ46604.1 - 4.3 6.9 13.4 5.6 6.6 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) zf-C3HC4_3 PF13920.6 KXZ46608.1 - 5.1e-08 32.7 0.4 8.3e-08 32.0 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ46608.1 - 0.045 13.6 1.2 0.1 12.5 1.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ46608.1 - 0.19 12.1 1.5 0.45 10.9 1.5 1.7 1 0 0 1 1 1 0 Ring finger domain rRNA_proc-arch PF13234.6 KXZ46609.1 - 1.5e-14 54.6 0.0 2.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KXZ46609.1 - 1.5e-05 24.8 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ46609.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HalX PF08663.10 KXZ46609.1 - 2.2 8.7 5.3 0.51 10.7 1.2 2.0 2 0 0 2 2 2 0 HalX domain Inositol_P PF00459.25 KXZ46610.1 - 8.9e-61 205.8 0.1 1.1e-60 205.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family AAA_5 PF07728.14 KXZ46611.1 - 5.1e-23 81.6 0.0 1.1e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 KXZ46611.1 - 1.5e-22 79.2 0.0 3.4e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KXZ46611.1 - 0.0002 21.2 0.0 0.00043 20.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXZ46611.1 - 0.0024 17.3 0.0 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 KXZ46611.1 - 0.032 14.6 0.0 0.21 12.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ46611.1 - 0.11 12.9 2.5 0.19 12.1 0.2 2.6 2 2 0 2 2 2 0 AAA ATPase domain DUF4464 PF14713.6 KXZ46612.1 - 1.6e-98 328.8 1.4 1.9e-98 328.5 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) FAD_binding_8 PF08022.12 KXZ46614.1 - 4.3e-14 52.5 0.0 7.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXZ46614.1 - 8.5e-14 51.7 11.4 8.5e-14 51.7 11.4 2.6 3 0 0 3 3 3 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXZ46614.1 - 1.2e-06 28.7 0.0 1e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXZ46615.1 - 1.9e-16 60.1 0.0 3.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXZ46615.1 - 3.1e-13 49.9 11.3 3.1e-13 49.9 11.3 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXZ46615.1 - 4.8e-10 39.8 0.0 2e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KXZ46615.1 - 0.0036 17.9 0.0 0.0085 16.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2368 PF10166.9 KXZ46615.1 - 0.12 11.9 0.2 0.3 10.7 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) LCAT PF02450.15 KXZ46616.1 - 9.1e-69 232.5 0.0 6.6e-58 196.7 0.0 3.1 3 0 0 3 3 3 3 Lecithin:cholesterol acyltransferase Trp_Tyr_perm PF03222.13 KXZ46616.1 - 0.26 10.3 0.0 0.39 9.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Pkinase PF00069.25 KXZ46617.1 - 5.1e-20 72.0 0.0 1.2e-08 34.7 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46617.1 - 1.5e-18 67.0 0.0 1.1e-08 34.8 0.0 3.6 2 1 1 3 3 3 3 Protein tyrosine kinase Ferric_reduct PF01794.19 KXZ46618.1 - 1.5e-14 54.2 7.8 1.5e-14 54.2 7.8 3.2 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXZ46618.1 - 1.5e-12 47.9 0.0 4.8e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXZ46618.1 - 1.8e-12 47.3 0.0 3.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXZ46618.1 - 0.094 13.4 0.0 0.24 12.1 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ferric_reduct PF01794.19 KXZ46619.1 - 5.3e-07 29.8 0.3 5.3e-07 29.8 0.3 2.9 3 1 1 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXZ46620.1 - 1.1e-13 51.6 0.0 3.3e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXZ46620.1 - 7e-12 45.4 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXZ46620.1 - 0.011 16.4 0.0 0.04 14.6 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain OAD_gamma PF04277.13 KXZ46620.1 - 0.16 12.6 1.0 0.88 10.2 0.6 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Potass_KdpF PF09604.10 KXZ46620.1 - 0.42 10.7 2.1 1.5 8.9 2.1 2.1 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) HMG_box PF00505.19 KXZ46621.1 - 5.7e-07 29.9 2.3 5.7e-07 29.9 2.3 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXZ46621.1 - 1.8e-06 28.4 2.4 1.8e-06 28.4 2.4 2.8 3 0 0 3 3 3 1 HMG-box domain CASP_C PF08172.12 KXZ46623.1 - 0.23 10.8 1.9 0.46 9.8 0.3 2.0 2 0 0 2 2 2 0 CASP C terminal Amidohydro_1 PF01979.20 KXZ46624.1 - 0.096 12.0 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Amidohydrolase family Ank_2 PF12796.7 KXZ46625.1 - 1.6e-06 28.6 1.0 0.00016 22.2 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46625.1 - 1.9e-06 28.3 4.4 0.16 12.6 0.1 6.0 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ46625.1 - 0.0016 18.7 4.3 5.5 7.4 0.1 5.7 4 1 2 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46625.1 - 0.0083 16.6 5.1 49 5.0 0.0 6.5 7 0 0 7 7 7 0 Ankyrin repeat DUF1115 PF06544.12 KXZ46626.1 - 4.8e-09 36.5 0.0 7.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF3138 PF11336.8 KXZ46626.1 - 4.3 5.8 9.0 2.8 6.4 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Amnionless PF14828.6 KXZ46628.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless Herpes_gE PF02480.16 KXZ46628.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KXZ46628.1 - 0.19 12.6 0.0 0.36 11.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Exostosin PF03016.15 KXZ46629.1 - 5.1e-29 101.4 0.0 7.6e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ46629.1 - 2.6e-10 40.5 40.0 1.6e-05 25.1 11.6 3.8 3 0 0 3 3 3 2 EGF-like domain EGF PF00008.27 KXZ46629.1 - 1.7 9.1 33.6 3.9 7.9 9.5 3.7 2 1 1 3 3 3 0 EGF-like domain Laminin_EGF PF00053.24 KXZ46629.1 - 2.6 8.3 29.2 34 4.7 15.2 2.9 1 1 1 2 2 2 0 Laminin EGF domain Trypsin_2 PF13365.6 KXZ46630.1 - 1e-24 88.2 9.9 6.7e-20 72.5 0.2 2.7 2 1 1 3 3 3 2 Trypsin-like peptidase domain Trypsin PF00089.26 KXZ46630.1 - 5.4e-09 36.2 0.2 8.2e-05 22.5 0.0 2.6 1 1 1 2 2 2 2 Trypsin PDZ_2 PF13180.6 KXZ46630.1 - 2.1e-06 28.0 0.0 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Peptidase_S29 PF02907.15 KXZ46630.1 - 4.1e-06 26.6 0.0 7.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease PDZ_6 PF17820.1 KXZ46630.1 - 6.8e-05 22.6 1.5 0.042 13.7 0.0 2.8 2 0 0 2 2 2 2 PDZ domain Peptidase_S46 PF10459.9 KXZ46630.1 - 0.022 13.4 0.3 0.078 11.6 0.2 1.7 2 0 0 2 2 2 0 Peptidase S46 PDZ PF00595.24 KXZ46630.1 - 0.25 11.7 1.2 3.7 8.0 1.2 2.4 1 1 0 1 1 1 0 PDZ domain Pkinase PF00069.25 KXZ46631.1 - 1.1e-33 116.7 0.0 3.1e-20 72.6 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46631.1 - 1.3e-31 109.9 0.0 3.6e-26 92.0 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ46631.1 - 0.029 14.3 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Spike_rec_bind PF09408.10 KXZ46631.1 - 0.041 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Spike receptor binding domain Ribonuclease_3 PF00636.26 KXZ46632.1 - 0.067 13.8 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease III domain TPX2_importin PF12214.8 KXZ46633.1 - 8e-27 94.5 24.7 9.1e-19 68.3 2.1 5.6 1 1 2 5 5 5 4 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 KXZ46633.1 - 2e-09 37.6 10.1 2e-09 37.6 10.1 3.7 5 0 0 5 5 5 1 Targeting protein for Xklp2 (TPX2) Ribosomal_L14e PF01929.17 KXZ46633.1 - 0.026 15.0 0.4 0.081 13.4 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein L14 Ras PF00071.22 KXZ46634.1 - 1e-13 51.2 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Aminotran_1_2 PF00155.21 KXZ46635.1 - 9e-31 107.3 0.0 1.6e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXZ46635.1 - 3.1e-10 39.4 0.0 4.6e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase TetR_C_14 PF17754.1 KXZ46635.1 - 0.94 9.4 6.9 1.1 9.2 0.1 4.0 4 1 1 5 5 5 0 MftR C-terminal domain AAA_34 PF13872.6 KXZ46636.1 - 4.7e-99 331.1 0.0 1.7e-98 329.2 0.0 2.0 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 KXZ46636.1 - 3.2e-95 318.9 0.0 6.1e-95 318.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue PHD PF00628.29 KXZ46636.1 - 8.1e-13 48.1 3.5 1.4e-12 47.3 3.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXZ46636.1 - 0.00083 18.9 0.6 0.0015 18.0 0.6 1.5 1 0 0 1 1 1 1 PHD-finger Helicase_C PF00271.31 KXZ46636.1 - 0.08 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RanBP PF00641.18 KXZ46636.1 - 0.2 11.0 1.4 0.37 10.2 1.4 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Zf_RING PF16744.5 KXZ46636.1 - 0.42 10.8 1.2 1.1 9.4 0.3 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger Bestrophin PF01062.21 KXZ46637.1 - 1.2e-40 139.8 1.5 1.4e-40 139.5 1.5 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Glyco_transf_34 PF05637.12 KXZ46638.1 - 2.6e-19 69.9 0.0 1.6e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family Glyco_transf_21 PF13506.6 KXZ46638.1 - 0.18 11.3 0.5 5.1 6.5 0.5 2.6 1 1 0 1 1 1 0 Glycosyl transferase family 21 SRP19 PF01922.17 KXZ46639.1 - 2.9e-09 37.7 0.0 4.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein AhpC-TSA PF00578.21 KXZ46640.1 - 1.1e-24 86.8 0.0 1.3e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ46640.1 - 2.2e-14 53.4 0.0 2.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Pentapeptide_2 PF01469.18 KXZ46641.1 - 3.7e-07 29.9 9.8 1e-06 28.5 9.8 1.8 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) ShK PF01549.24 KXZ46641.1 - 1 10.0 106.2 1.8 9.1 2.9 10.0 9 1 0 9 9 9 0 ShK domain-like CitMHS PF03600.16 KXZ46642.1 - 3e-28 98.9 23.9 4.9e-28 98.2 23.9 1.4 1 0 0 1 1 1 1 Citrate transporter DUF1646 PF07854.12 KXZ46642.1 - 0.062 12.7 3.0 2.6 7.3 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1646) CitMHS_2 PF16980.5 KXZ46642.1 - 0.4 9.3 7.5 1.2 7.8 0.1 3.1 2 1 0 3 3 3 0 Putative citrate transport DUF1764 PF08576.10 KXZ46643.1 - 1.4e-25 90.1 6.2 1.4e-25 90.1 6.2 2.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Sec62 PF03839.16 KXZ46643.1 - 2.3 7.7 7.9 2.7 7.4 7.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RPE65 PF03055.15 KXZ46644.1 - 3.3e-45 155.2 0.0 1.7e-36 126.5 0.0 2.1 2 0 0 2 2 2 2 Retinal pigment epithelial membrane protein DUF3707 PF12499.8 KXZ46645.1 - 3.2e-50 170.4 24.1 1.4e-25 90.6 5.3 2.1 2 0 0 2 2 2 2 Pherophorin Ribosomal_S11 PF00411.19 KXZ46647.1 - 4.1e-48 162.4 1.0 5.1e-48 162.1 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KXZ46647.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) DUF3883 PF13020.6 KXZ46648.1 - 3.8e-17 62.1 0.0 7.3e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) SecD-TM1 PF13721.6 KXZ46648.1 - 0.023 15.2 0.0 0.069 13.6 0.0 1.8 1 0 0 1 1 1 0 SecD export protein N-terminal TM region DUF3883 PF13020.6 KXZ46649.1 - 2.6e-13 49.8 0.0 3.9e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) OST-HTH PF12872.7 KXZ46649.1 - 0.00037 20.2 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Ion_trans PF00520.31 KXZ46650.1 - 4.4e-05 22.8 0.7 4.4e-05 22.8 0.7 1.1 1 0 0 1 1 1 1 Ion transport protein Methyltransf_32 PF13679.6 KXZ46652.1 - 0.0075 16.3 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Mis12 PF05859.12 KXZ46652.1 - 0.078 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Mis12 protein ATG16 PF08614.11 KXZ46652.1 - 0.079 13.2 1.0 0.18 12.0 1.0 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 KXZ46652.1 - 0.15 12.2 1.2 6.9 6.8 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) UCH PF00443.29 KXZ46653.1 - 1.8e-44 152.2 0.0 2.1e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ46653.1 - 1.8e-18 67.3 0.0 4.8e-16 59.2 0.0 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MSP1_C PF07462.11 KXZ46653.1 - 1.1 7.9 1.9 1.7 7.3 1.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AF-4 PF05110.13 KXZ46653.1 - 6.4 4.7 7.1 9.5 4.2 7.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase_Tyr PF07714.17 KXZ46655.1 - 5.9e-22 78.2 0.0 2.8e-07 30.1 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ46655.1 - 3.2e-21 75.9 0.0 5.4e-20 71.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain CENP-T_C PF15511.6 KXZ46656.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46656.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ46656.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ46656.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46656.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ46656.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ46656.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated SRCR PF00530.18 KXZ46657.1 - 1.1e-24 86.8 0.1 2.2e-13 50.5 0.5 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ46657.1 - 0.1 13.1 0.0 1.5 9.4 0.0 2.2 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain Histone PF00125.24 KXZ46658.1 - 3e-22 79.4 4.8 4e-22 79.0 4.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46658.1 - 2.8e-05 24.3 0.1 8.4e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ46658.1 - 0.0019 18.6 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ46658.1 - 0.021 14.9 5.1 0.037 14.1 5.1 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ46658.1 - 0.029 14.0 0.6 1.3 8.6 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain RNA_pol_Rpc4 PF05132.14 KXZ46658.1 - 9.7 6.6 12.1 21 5.5 12.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Histone_H2A_C PF16211.5 KXZ46659.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ46659.1 - 6.3e-17 62.2 0.0 8.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46659.1 - 3.4e-05 24.0 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KXZ46660.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46660.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ46660.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ46660.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46660.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ46660.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ46660.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ46662.1 - 1.3e-11 45.0 0.0 1.4e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46662.1 - 0.0038 17.5 0.0 0.0056 16.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46663.1 - 2.8e-22 79.5 4.4 3.7e-22 79.1 4.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46663.1 - 2.8e-05 24.3 0.1 8.4e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ46663.1 - 0.0019 18.6 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ46663.1 - 0.024 14.7 5.3 0.044 13.8 5.3 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ46663.1 - 0.031 14.0 0.7 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain RNA_pol_Rpc4 PF05132.14 KXZ46663.1 - 7.5 7.0 11.6 15 6.0 11.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 SRCR PF00530.18 KXZ46664.1 - 0.069 13.7 0.2 0.13 12.8 0.2 1.4 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain CENP-T_C PF15511.6 KXZ46665.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ46665.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ46665.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ46665.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46665.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ46665.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ46665.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated ADIP PF11559.8 KXZ46666.1 - 0.018 15.1 31.5 1.4 8.9 8.5 3.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.22 KXZ46666.1 - 0.019 15.2 25.1 0.15 12.3 4.5 4.1 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Lipoprotein_6 PF01441.19 KXZ46666.1 - 0.031 14.3 4.5 0.18 11.8 1.8 2.5 1 1 0 2 2 2 0 Lipoprotein Fez1 PF06818.15 KXZ46666.1 - 0.2 12.1 30.4 1.1 9.7 0.9 3.2 2 1 1 3 3 3 0 Fez1 Syntaxin_2 PF14523.6 KXZ46666.1 - 0.21 12.0 12.0 0.13 12.7 6.0 2.8 2 2 0 2 2 2 0 Syntaxin-like protein Laminin_II PF06009.12 KXZ46666.1 - 0.31 11.1 18.1 1.9 8.5 0.7 4.0 2 2 2 4 4 4 0 Laminin Domain II AAA_13 PF13166.6 KXZ46666.1 - 0.31 9.6 19.3 0.2 10.2 3.2 3.0 2 1 1 3 3 3 0 AAA domain FliD_C PF07195.12 KXZ46666.1 - 0.48 9.8 5.0 13 5.1 1.4 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spc7 PF08317.11 KXZ46666.1 - 0.62 8.9 36.8 1.5 7.6 7.6 3.8 2 2 2 4 4 4 0 Spc7 kinetochore protein TMPIT PF07851.13 KXZ46666.1 - 0.62 9.3 10.3 0.36 10.0 3.2 2.4 2 0 0 2 2 2 0 TMPIT-like protein TraT PF05818.12 KXZ46666.1 - 0.75 9.4 2.8 1.4 8.5 2.8 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Sec2p PF06428.11 KXZ46666.1 - 0.82 9.7 28.3 0.059 13.3 4.5 4.9 3 2 3 6 6 6 0 GDP/GTP exchange factor Sec2p Prominin PF05478.11 KXZ46666.1 - 1.1 7.2 7.5 0.49 8.3 0.9 2.3 2 0 0 2 2 2 0 Prominin Fib_alpha PF08702.10 KXZ46666.1 - 1.2 9.3 7.3 5.8 7.1 3.0 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.15 KXZ46666.1 - 2.2 8.4 8.9 1.1 9.4 3.8 2.6 2 1 1 3 3 3 0 RasGAP C-terminus GAS PF13851.6 KXZ46666.1 - 2.9 7.2 33.6 2.8 7.2 3.3 3.7 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding Sec8_exocyst PF04048.14 KXZ46666.1 - 2.9 7.8 10.4 5.9 6.8 0.5 4.1 3 1 2 5 5 5 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 KXZ46666.1 - 5.3 7.1 9.6 9.4 6.3 1.3 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Nup88 PF10168.9 KXZ46666.1 - 5.7 4.6 14.3 2.1 6.1 3.9 2.1 2 0 0 2 2 2 0 Nuclear pore component IFT57 PF10498.9 KXZ46666.1 - 5.9 5.8 13.9 0.71 8.8 2.2 2.7 2 1 0 3 3 3 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 KXZ46666.1 - 7.3 6.6 10.1 29 4.7 0.9 4.0 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 KXZ46666.1 - 7.5 6.1 20.7 2.4 7.7 10.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) ERM PF00769.19 KXZ46666.1 - 8.8 6.1 57.1 0.45 10.3 29.6 3.4 2 2 1 3 3 3 0 Ezrin/radixin/moesin family AftA_C PF12249.8 KXZ46667.1 - 0.23 11.1 1.4 0.36 10.5 1.4 1.2 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal Draxin PF15550.6 KXZ46667.1 - 0.49 10.2 9.1 4.9 6.9 6.7 2.2 2 0 0 2 2 2 0 Draxin Presenilin PF01080.17 KXZ46667.1 - 1.3 7.7 4.3 1.8 7.2 4.3 1.1 1 0 0 1 1 1 0 Presenilin Alpha-amylase_C PF02806.18 KXZ46668.1 - 2.3e-18 66.5 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain NYD-SP28_assoc PF14775.6 KXZ46668.1 - 0.041 14.0 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain Histone PF00125.24 KXZ46669.1 - 6.1e-48 162.5 0.3 6.7e-48 162.4 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ46669.1 - 9.5e-05 22.7 0.0 0.00013 22.3 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ46669.1 - 0.00029 20.9 0.1 0.00038 20.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ46669.1 - 0.0036 17.5 0.1 0.005 17.1 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ46669.1 - 0.0071 16.4 0.0 0.0098 16.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone_H2A_C PF16211.5 KXZ46670.1 - 5.1e-19 67.7 1.6 9.4e-19 66.9 1.6 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ46670.1 - 6.4e-17 62.1 0.0 8.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46670.1 - 3.4e-05 24.0 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46671.1 - 9.5e-39 132.8 0.7 1.1e-38 132.5 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ46671.1 - 5e-05 23.6 0.0 6.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ46671.1 - 0.00017 21.7 0.1 0.0002 21.4 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ46671.1 - 0.0014 18.8 0.1 0.0026 18.0 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ46671.1 - 0.0039 17.2 0.0 0.0049 16.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF4840 PF16128.5 KXZ46671.1 - 0.19 11.8 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) Histone_H2A_C PF16211.5 KXZ46672.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ46672.1 - 6.3e-17 62.2 0.0 8.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46672.1 - 3.4e-05 24.0 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DSHCT PF08148.12 KXZ46673.1 - 4e-29 101.4 4.5 4.1e-15 55.8 0.4 2.0 1 1 1 2 2 2 2 DSHCT (NUC185) domain Histone PF00125.24 KXZ46674.1 - 5.1e-48 162.8 0.1 5.7e-48 162.6 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ46674.1 - 0.00014 22.1 0.0 0.0002 21.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ46674.1 - 0.00046 20.3 0.1 0.00062 19.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ46674.1 - 0.0054 17.0 0.1 0.0079 16.5 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ46674.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KXZ46675.1 - 1.9e-22 80.0 4.4 2.6e-22 79.6 4.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46675.1 - 2.8e-05 24.3 0.1 8.4e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ46675.1 - 0.0019 18.6 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ46675.1 - 0.015 15.4 4.6 0.027 14.5 4.6 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ46675.1 - 0.03 14.0 0.7 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain RNA_pol_Rpc4 PF05132.14 KXZ46675.1 - 6.4 7.2 11.7 13 6.2 11.7 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Histone_H2A_C PF16211.5 KXZ46676.1 - 3.3e-19 68.3 2.2 5.5e-19 67.6 2.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ46676.1 - 8.9e-17 61.7 0.0 1.1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46676.1 - 3.5e-05 24.0 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone rRNA_proc-arch PF13234.6 KXZ46677.1 - 4.8e-63 213.6 0.0 6.3e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KXZ46677.1 - 4.1e-27 94.9 0.0 6.9e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain APG6_N PF17675.1 KXZ46677.1 - 0.0056 17.2 0.8 0.012 16.1 0.8 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region HMMR_N PF15905.5 KXZ46677.1 - 0.0058 16.1 0.4 0.0087 15.6 0.4 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ABC_tran_CTD PF16326.5 KXZ46677.1 - 0.062 13.6 8.8 0.14 12.4 3.2 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 KXZ46677.1 - 0.079 13.1 0.5 0.19 11.8 0.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor Fer2 PF00111.27 KXZ46678.1 - 1.8e-07 31.0 0.3 3.2e-07 30.2 0.3 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 KXZ46678.1 - 2e-05 24.5 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Arf PF00025.21 KXZ46679.1 - 8.1e-70 233.8 0.1 9.1e-70 233.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXZ46679.1 - 1.7e-12 47.6 0.0 2.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXZ46679.1 - 1.6e-11 44.0 0.7 1.2e-06 28.0 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXZ46679.1 - 2.3e-10 40.3 0.0 2.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KXZ46679.1 - 3.2e-09 36.5 0.0 4.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXZ46679.1 - 1.1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXZ46679.1 - 1.1e-07 31.9 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ46679.1 - 0.0013 18.3 0.2 0.0043 16.6 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KXZ46679.1 - 0.025 14.3 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.18 KXZ46679.1 - 0.042 13.1 0.1 0.058 12.7 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF1073 PF06381.11 KXZ46679.1 - 0.054 12.3 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) TniB PF05621.11 KXZ46679.1 - 0.092 12.2 0.2 0.2 11.1 0.1 1.6 2 0 0 2 2 2 0 Bacterial TniB protein PPK2 PF03976.14 KXZ46679.1 - 0.29 10.6 0.1 0.29 10.6 0.1 1.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) Cupin_2 PF07883.11 KXZ46680.1 - 4.4e-14 51.9 0.0 4.1e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXZ46680.1 - 6.7e-08 32.1 0.0 1e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXZ46680.1 - 8.6e-07 28.9 0.0 0.0024 17.8 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Pirin_C PF05726.13 KXZ46680.1 - 0.069 13.5 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Pirin C-terminal cupin domain PPK2 PF03976.14 KXZ46681.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Histone_H2A_C PF16211.5 KXZ46682.1 - 3.3e-19 68.3 1.9 6.1e-19 67.5 1.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ46682.1 - 6.1e-17 62.2 0.0 8.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46682.1 - 3.4e-05 24.1 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ46683.1 - 1.9e-22 80.0 4.4 2.6e-22 79.6 4.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ46683.1 - 2.8e-05 24.3 0.1 8.4e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ46683.1 - 0.0019 18.6 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ46683.1 - 0.015 15.4 4.6 0.027 14.5 4.6 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ46683.1 - 0.03 14.0 0.7 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain RNA_pol_Rpc4 PF05132.14 KXZ46683.1 - 6.4 7.2 11.7 13 6.2 11.7 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 zf-MYND PF01753.18 KXZ46684.1 - 8.1e-10 38.6 8.2 8.1e-10 38.6 8.2 2.1 2 0 0 2 2 2 1 MYND finger Histone PF00125.24 KXZ46685.1 - 2.4e-47 160.6 0.1 4.1e-47 159.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ46685.1 - 0.00075 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ46685.1 - 0.0022 18.1 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ46685.1 - 0.031 14.6 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ46685.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit NARP1 PF12569.8 KXZ46687.1 - 0.17 10.8 5.2 0.24 10.3 5.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CPSF100_C PF13299.6 KXZ46687.1 - 2.2 8.5 6.8 4.4 7.5 6.8 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 KXZ46687.1 - 2.3 8.0 4.4 3.6 7.3 4.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KXZ46687.1 - 6.5 5.4 5.1 9.4 4.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin Caleosin PF05042.13 KXZ46688.1 - 9.1e-59 198.2 0.0 1.2e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_8 PF13833.6 KXZ46688.1 - 0.00017 21.4 0.1 0.0005 19.9 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ46688.1 - 0.0044 16.9 0.4 0.027 14.4 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KXZ46688.1 - 0.0061 16.0 0.1 0.024 14.2 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXZ46688.1 - 0.056 13.9 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair Methyltransf_25 PF13649.6 KXZ46689.1 - 4.3e-15 56.2 0.0 1.4e-14 54.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ46689.1 - 3.7e-12 46.7 1.3 4.8e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ46689.1 - 2e-11 44.0 0.0 2.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ46689.1 - 3.9e-10 40.3 0.4 1.2e-09 38.8 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ46689.1 - 1.7e-06 27.9 0.0 6.4e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ46689.1 - 1.6e-05 24.4 0.0 3.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KXZ46689.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF938) CheR PF01739.18 KXZ46689.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Guanylate_cyc PF00211.20 KXZ46692.1 - 4.7e-07 29.6 0.0 6.9e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF2306 PF10067.9 KXZ46693.1 - 3.2e-10 40.4 9.5 2.2e-06 28.0 0.6 2.6 2 0 0 2 2 2 2 Predicted membrane protein (DUF2306) SNF2_N PF00176.23 KXZ46694.1 - 2.2e-32 112.2 0.0 6.5e-32 110.6 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ46694.1 - 0.032 14.6 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Peptidase_S49_N PF08496.10 KXZ46694.1 - 0.077 13.1 0.0 0.077 13.1 0.0 3.5 3 1 1 4 4 4 0 Peptidase family S49 N-terminal DDHD PF02862.17 KXZ46694.1 - 8.9 6.4 10.6 35 4.5 6.5 3.1 2 0 0 2 2 2 0 DDHD domain Ank_2 PF12796.7 KXZ46695.1 - 8.6e-22 77.5 0.8 7e-10 39.4 0.2 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ46695.1 - 3.7e-17 62.2 6.3 2.3e-06 27.7 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ46695.1 - 7.8e-16 58.2 4.2 6e-09 36.3 0.2 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46695.1 - 2.5e-10 40.3 6.9 0.0023 18.3 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXZ46695.1 - 2.9e-10 39.5 5.6 0.17 12.5 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat DUF746 PF05344.11 KXZ46697.1 - 0.00068 19.4 0.1 0.0053 16.6 0.1 2.0 1 1 0 1 1 1 1 Domain of Unknown Function (DUF746) DUF1993 PF09351.10 KXZ46697.1 - 0.02 15.0 1.3 0.024 14.8 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) SRA1 PF07304.11 KXZ46697.1 - 0.06 13.1 1.5 0.078 12.8 1.5 1.2 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF2232 PF09991.9 KXZ46697.1 - 0.13 11.4 4.2 0.62 9.2 0.2 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) sCache_2 PF17200.4 KXZ46697.1 - 0.2 11.5 2.9 0.45 10.4 2.9 1.7 1 1 0 1 1 1 0 Single Cache domain 2 Band_7_C PF16200.5 KXZ46697.1 - 1.8 8.6 5.8 13 5.9 0.9 2.4 3 0 0 3 3 3 0 C-terminal region of band_7 Ank_5 PF13857.6 KXZ46698.1 - 1.8e-20 72.7 3.0 1.9e-07 31.2 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ46698.1 - 1.1e-19 70.7 0.5 1.2e-10 41.8 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ46698.1 - 3.7e-18 63.7 1.4 0.0012 19.1 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ46698.1 - 4.9e-17 62.1 1.0 3.3e-08 33.9 0.2 3.4 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46698.1 - 3.7e-15 55.6 4.1 0.0021 18.4 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat zf-C3HC4_3 PF13920.6 KXZ46698.1 - 1e-07 31.7 7.1 1e-07 31.7 7.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ46698.1 - 0.0053 17.1 9.3 0.0053 17.1 9.3 3.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KXZ46698.1 - 0.0061 16.4 8.1 0.0061 16.4 8.1 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ46698.1 - 0.012 15.5 8.6 0.012 15.5 8.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXZ46698.1 - 1 9.4 15.7 0.31 11.0 9.0 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXZ46698.1 - 1.1 9.3 5.2 1.4 9.0 3.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger TFIIA PF03153.13 KXZ46698.1 - 4.9 7.0 9.1 12 5.8 2.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.6 KXZ46698.1 - 9.9 6.4 11.5 32 4.8 11.5 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Hist_deacetyl PF00850.19 KXZ46700.1 - 4.7e-62 210.2 0.3 3.5e-61 207.3 0.3 1.9 1 1 0 1 1 1 1 Histone deacetylase domain Dev_Cell_Death PF10539.9 KXZ46701.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Development and cell death domain Sybindin PF04099.12 KXZ46703.1 - 6.1e-21 74.8 0.0 7.6e-10 38.9 0.1 2.0 1 1 0 2 2 2 2 Sybindin-like family Cyclin_N PF00134.23 KXZ46704.1 - 3.5e-23 81.7 0.1 3.3e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ46704.1 - 7.3e-07 29.3 0.2 1.8e-06 28.1 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain EF-hand_1 PF00036.32 KXZ46705.1 - 2e-24 83.3 1.7 4.9e-06 25.7 0.1 5.3 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 KXZ46705.1 - 1.4e-21 74.5 0.3 8.5e-05 22.2 0.2 5.4 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KXZ46705.1 - 2.8e-20 72.6 0.6 0.00065 20.1 0.0 4.5 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXZ46705.1 - 2e-15 55.4 4.2 7.5e-05 22.0 0.0 4.8 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXZ46705.1 - 2.3e-14 53.0 6.8 0.00011 22.0 0.2 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KXZ46705.1 - 0.07 13.1 0.1 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF5421 PF17458.2 KXZ46707.1 - 0.2 11.0 2.1 0.33 10.3 2.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF4205 PF13898.6 KXZ46708.1 - 1.4e-85 287.3 0.0 1.7e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) IL11 PF07400.11 KXZ46708.1 - 0.042 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Interleukin 11 SOUL PF04832.12 KXZ46708.1 - 0.085 13.0 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 SOUL heme-binding protein BaxI_1 PF12811.7 KXZ46709.1 - 1.1e-65 221.5 20.8 1.3e-65 221.2 20.8 1.0 1 0 0 1 1 1 1 Bax inhibitor 1 like Vasculin PF15337.6 KXZ46710.1 - 0.0053 17.6 0.6 0.01 16.6 0.6 1.4 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 p47_phox_C PF08944.11 KXZ46710.1 - 3.2 7.3 7.1 10 5.6 7.1 1.9 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain ANAPC4_WD40 PF12894.7 KXZ46711.1 - 3.9e-08 33.5 0.0 0.00057 20.1 0.0 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 KXZ46711.1 - 9.8e-07 28.6 0.1 1.1e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KXZ46711.1 - 2.1e-06 28.3 8.7 0.0022 18.8 0.3 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Lgl_C PF08596.10 KXZ46711.1 - 0.034 12.9 0.0 0.07 11.8 0.0 1.5 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal Cmc1 PF08583.10 KXZ46712.1 - 3.4e-06 27.0 0.2 3.4e-06 27.0 0.2 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KXZ46712.1 - 0.0015 18.2 0.8 0.0045 16.7 0.9 1.7 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KXZ46712.1 - 0.0045 17.0 0.1 0.0071 16.3 0.1 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Methyltransf_25 PF13649.6 KXZ46713.1 - 1.3e-14 54.7 0.0 3.3e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ46713.1 - 4.6e-12 46.4 0.0 1.2e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ46713.1 - 7.1e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ46713.1 - 2.5e-09 37.8 0.0 6.4e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ46713.1 - 2e-05 24.4 0.0 6.5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ46713.1 - 4.4e-05 22.9 0.0 0.0001 21.7 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KXZ46713.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KXZ46714.1 - 1.2e-14 54.8 0.0 2.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ46714.1 - 4.4e-12 46.5 0.0 9.3e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ46714.1 - 3.1e-11 43.4 0.0 5.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ46714.1 - 6.1e-10 39.7 0.0 1.1e-09 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ46714.1 - 6.4e-06 26.0 0.0 2.1e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ46714.1 - 4.1e-05 23.0 0.0 9.5e-05 21.8 0.0 1.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KXZ46714.1 - 0.022 14.5 0.0 0.089 12.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF938) Mito_carr PF00153.27 KXZ46715.1 - 2.9e-53 177.8 6.5 5.4e-19 67.9 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein EamA PF00892.20 KXZ46716.1 - 2e-17 63.6 19.4 6.1e-11 42.6 10.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family CfAFP PF05264.11 KXZ46717.1 - 0.059 13.4 0.0 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Tox-SGS PF15651.6 KXZ46717.1 - 0.096 12.9 0.0 25 5.2 0.0 2.5 2 0 0 2 2 2 0 Salivary glad secreted protein domain toxin TonB_N PF16031.5 KXZ46717.1 - 0.93 10.0 46.4 3.9 8.0 19.1 2.5 2 0 0 2 2 2 0 TonB polyproline region Trypan_PARP PF05887.11 KXZ46717.1 - 4.1 7.4 24.0 8.1 6.4 8.3 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Aminotran_1_2 PF00155.21 KXZ46718.1 - 2e-34 119.4 0.0 2.4e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CDKN3 PF05706.12 KXZ46719.1 - 1.3e-05 25.0 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 KXZ46719.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXZ46719.1 - 0.031 14.2 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXZ46719.1 - 0.045 13.3 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXZ46719.1 - 0.046 13.8 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Rhodanese PF00581.20 KXZ46719.1 - 0.15 12.6 0.0 5.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain Rubredoxin PF00301.20 KXZ46720.1 - 5.5e-06 26.3 5.4 0.0015 18.5 5.4 2.4 1 1 0 1 1 1 1 Rubredoxin TF_Zn_Ribbon PF08271.12 KXZ46720.1 - 0.02 14.4 1.0 1.9 8.0 0.5 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KXZ46720.1 - 0.023 14.8 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 KXZ46720.1 - 0.092 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 KXZ46720.1 - 0.19 11.5 2.8 0.59 9.9 0.2 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain NusG PF02357.19 KXZ46722.1 - 0.036 14.6 0.1 0.062 13.8 0.1 1.4 1 0 0 1 1 1 0 Transcription termination factor nusG RNase_PH PF01138.21 KXZ46723.1 - 1.3e-35 122.7 0.3 1.8e-35 122.3 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXZ46723.1 - 2.2e-08 34.0 0.0 4.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NIF PF03031.18 KXZ46724.1 - 1.5e-53 180.7 0.0 1.7e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UPF0489 PF12640.7 KXZ46724.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 UPF0489 domain Smr PF01713.21 KXZ46725.1 - 4.3e-06 27.0 0.0 1.8e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 KXZ46725.1 - 0.00038 20.1 0.7 0.072 12.8 0.1 2.7 2 0 0 2 2 2 2 CUE domain adh_short_C2 PF13561.6 KXZ46727.1 - 4.3e-47 160.7 0.7 1.1e-46 159.3 0.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ46727.1 - 8.7e-45 152.6 0.1 1.3e-44 152.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ46727.1 - 2.7e-09 37.2 0.4 7.5e-09 35.8 0.6 1.5 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KXZ46727.1 - 1.6e-05 25.1 0.2 3.5e-05 24.1 0.2 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXZ46727.1 - 0.00029 20.4 0.0 0.00055 19.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXZ46727.1 - 0.0011 18.6 0.6 0.0015 18.1 0.6 1.2 1 0 0 1 1 1 1 NmrA-like family DFP PF04127.15 KXZ46727.1 - 0.02 14.8 0.8 0.087 12.7 0.1 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Flot PF15975.5 KXZ46727.1 - 0.042 14.0 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Flotillin RmlD_sub_bind PF04321.17 KXZ46727.1 - 0.051 12.7 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 KXZ46727.1 - 0.084 12.6 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.18 KXZ46727.1 - 0.093 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXZ46727.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_15 PF09445.10 KXZ46728.1 - 1.9e-32 112.1 0.0 4.1e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 KXZ46728.1 - 1.4e-06 28.2 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KXZ46728.1 - 3.2e-06 27.7 0.0 8.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain WW PF00397.26 KXZ46728.1 - 1e-05 25.5 2.0 2.4e-05 24.3 2.0 1.7 1 0 0 1 1 1 1 WW domain Methyltransf_31 PF13847.6 KXZ46728.1 - 5.7e-05 22.9 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ46728.1 - 0.00049 19.7 0.0 0.00094 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KXZ46728.1 - 0.0017 18.9 0.1 0.0065 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXZ46728.1 - 0.0042 16.6 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 KXZ46728.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KXZ46728.1 - 0.028 14.1 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KXZ46728.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CH_2 PF06294.11 KXZ46729.1 - 9.2e-21 73.8 0.6 1.9e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KXZ46729.1 - 1.7e-05 24.6 0.3 3.3e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 CAMSAP CH domain DUF641 PF04859.12 KXZ46729.1 - 0.0056 17.0 0.5 0.011 16.1 0.5 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) XLF PF09302.11 KXZ46729.1 - 0.0062 16.7 0.4 0.0098 16.1 0.4 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component NPIP PF06409.11 KXZ46729.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex interacting protein (NPIP) PKcGMP_CC PF16808.5 KXZ46729.1 - 0.017 15.0 5.3 0.62 10.0 1.1 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 KXZ46729.1 - 0.092 12.8 3.7 0.35 10.9 3.7 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding VGPC1_C PF16799.5 KXZ46729.1 - 0.15 12.1 3.6 0.15 12.1 0.9 2.2 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 EF-hand_8 PF13833.6 KXZ46730.1 - 0.0045 16.8 0.2 1.8 8.5 0.2 2.8 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ46730.1 - 0.0069 16.2 0.3 0.27 11.3 0.2 2.7 3 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KXZ46730.1 - 0.028 14.9 0.0 2.5 8.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KXZ46730.1 - 0.082 12.5 2.5 0.23 11.1 0.2 2.9 4 0 0 4 4 4 0 EF hand LRR_8 PF13855.6 KXZ46731.1 - 4.7e-07 29.5 2.4 2e-06 27.5 2.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KXZ46731.1 - 6.8e-05 23.2 1.4 0.00013 22.3 0.7 1.8 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ46731.1 - 0.15 12.2 2.4 3.2 8.0 0.2 2.7 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 KXZ46731.1 - 0.3 11.8 3.4 7 7.6 1.8 2.9 2 1 0 2 2 2 0 Leucine Rich Repeat F-box-like PF12937.7 KXZ46732.1 - 2.7e-05 24.0 0.9 5e-05 23.1 0.9 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ46732.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 KXZ46732.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 F-box Ribosomal_S7 PF00177.21 KXZ46735.1 - 4.9e-38 130.1 1.3 6e-38 129.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Helicase_C PF00271.31 KXZ46737.1 - 1.8e-28 99.1 0.0 3.1e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ46737.1 - 3.7e-25 88.7 0.0 7.2e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ46737.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NuA4 PF09340.10 KXZ46738.1 - 3.9e-06 26.6 0.7 1.1e-05 25.3 0.7 1.7 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 BSD PF03909.17 KXZ46739.1 - 7.8e-09 35.4 0.1 2.3e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 BSD domain DUF3150 PF11348.8 KXZ46740.1 - 0.13 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) DUF812 PF05667.11 KXZ46744.1 - 0.2 10.5 50.6 0.067 12.1 24.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 KXZ46744.1 - 0.55 10.3 54.5 0.075 13.0 11.7 5.3 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5-bind PF09311.11 KXZ46744.1 - 0.68 9.3 48.1 0.81 9.0 15.0 5.0 1 1 3 4 4 4 0 Rabaptin-like protein Mvb12 PF09452.10 KXZ46744.1 - 1.4 9.4 4.4 3 8.3 0.1 3.2 2 1 1 3 3 3 0 ESCRT-I subunit Mvb12 CCDC144C PF14915.6 KXZ46744.1 - 1.9 7.5 50.5 0.054 12.6 3.7 3.7 1 1 3 4 4 4 0 CCDC144C protein coiled-coil region HMMR_N PF15905.5 KXZ46744.1 - 4.6 6.6 48.7 0.76 9.2 7.2 4.1 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal RRM_1 PF00076.22 KXZ46745.1 - 1.2e-21 76.2 0.0 2.2e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ46745.1 - 0.0047 16.7 0.0 0.0091 15.8 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KXZ46745.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KXZ46745.1 - 0.04 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain RRM_7 PF16367.5 KXZ46745.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif FAD-oxidase_C PF02913.19 KXZ46746.1 - 4.6e-47 160.7 0.1 1e-46 159.6 0.1 1.6 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXZ46746.1 - 2.3e-27 95.5 1.0 7.9e-27 93.7 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Fer4_8 PF13183.6 KXZ46746.1 - 1.3e-09 38.4 4.1 3.3e-09 37.1 4.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXZ46746.1 - 1.5e-07 31.9 4.2 4.3e-07 30.4 4.2 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KXZ46746.1 - 1.6e-06 28.6 5.6 4.4e-06 27.1 5.6 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXZ46746.1 - 0.0011 19.8 4.8 0.003 18.4 4.8 1.8 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_20 PF14691.6 KXZ46746.1 - 0.0013 18.5 3.6 0.019 14.8 0.1 2.6 2 0 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_10 PF13237.6 KXZ46746.1 - 0.0017 18.4 6.2 0.018 15.2 6.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain CCG PF02754.16 KXZ46746.1 - 0.0018 18.4 9.9 0.0032 17.7 0.1 3.5 4 0 0 4 4 3 2 Cysteine-rich domain Fer4_21 PF14697.6 KXZ46746.1 - 0.011 15.9 2.3 1.2 9.4 0.4 2.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KXZ46746.1 - 0.018 15.5 2.6 0.018 15.5 2.6 2.3 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_9 PF13187.6 KXZ46746.1 - 0.08 13.1 7.9 0.25 11.5 1.2 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KXZ46746.1 - 0.28 11.4 10.0 0.039 14.1 3.6 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KXZ46746.1 - 0.96 9.6 10.4 0.067 13.3 3.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 KXZ46746.1 - 1.2 9.1 17.2 0.051 13.4 3.4 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Nucleotid_trans PF03407.16 KXZ46748.1 - 7e-44 150.3 0.3 8.8e-44 150.0 0.3 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-RING_2 PF13639.6 KXZ46749.1 - 2.1e-08 34.4 11.2 3.3e-08 33.7 11.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ46749.1 - 2.4e-05 24.1 11.3 3.8e-05 23.4 11.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXZ46749.1 - 4.9e-05 23.0 6.7 9.8e-05 22.0 6.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KXZ46749.1 - 0.0017 18.6 14.4 0.0048 17.1 14.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXZ46749.1 - 0.0026 17.6 10.7 0.0041 17.0 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXZ46749.1 - 0.058 13.0 8.8 0.1 12.3 8.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXZ46749.1 - 0.095 12.7 9.4 0.18 11.8 9.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DHHA1 PF02272.19 KXZ46749.1 - 0.15 12.5 0.1 0.2 12.1 0.1 1.1 1 0 0 1 1 1 0 DHHA1 domain zf-C3HC4_3 PF13920.6 KXZ46749.1 - 0.62 10.0 8.9 1 9.3 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXZ46749.1 - 1.4 9.2 12.6 1.3 9.2 10.0 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KXZ46749.1 - 2.6 8.2 9.0 5.7 7.1 9.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_S11 PF00411.19 KXZ46750.1 - 3.6e-31 107.8 0.1 5.2e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 TFIIF_alpha PF05793.12 KXZ46751.1 - 0.0056 15.3 46.4 0.86 8.1 41.7 3.3 2 2 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 KXZ46751.1 - 4.1 6.1 8.7 7.4 5.2 8.7 1.5 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 KXZ46751.1 - 5.3 6.6 12.2 11 5.6 12.2 1.4 1 0 0 1 1 1 0 Spt20 family DUF913 PF06025.12 KXZ46751.1 - 5.5 5.9 7.1 11 4.9 7.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PCRF PF03462.18 KXZ46752.1 - 4.9e-47 160.3 0.0 8.3e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KXZ46752.1 - 2.7e-26 91.8 0.3 5.3e-26 90.8 0.3 1.4 1 0 0 1 1 1 1 RF-1 domain TetR_C_33 PF13305.6 KXZ46753.1 - 0.17 12.6 2.7 1.4 9.7 0.1 2.4 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Cyclin_N PF00134.23 KXZ46753.1 - 0.24 11.1 0.1 0.39 10.5 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain SHMT PF00464.19 KXZ46754.1 - 3.3e-188 625.3 0.0 3.9e-188 625.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Taeniidae_ag PF05596.11 KXZ46754.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Taeniidae antigen DegT_DnrJ_EryC1 PF01041.17 KXZ46754.1 - 0.2 10.9 0.0 0.4 9.9 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family UBX PF00789.20 KXZ46755.1 - 1.4e-07 31.6 0.0 3.5e-07 30.3 0.0 1.7 2 0 0 2 2 1 1 UBX domain SEP PF08059.13 KXZ46755.1 - 4.4e-07 30.4 0.0 1.1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 SEP domain Cnn_1N PF07989.11 KXZ46755.1 - 0.11 12.7 0.9 0.29 11.3 0.9 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 CENP-H PF05837.12 KXZ46755.1 - 0.11 12.9 6.7 0.21 12.0 6.7 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-C4H2 PF10146.9 KXZ46755.1 - 0.14 12.4 1.0 0.29 11.4 1.0 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Spc7 PF08317.11 KXZ46755.1 - 0.16 10.8 2.5 0.26 10.1 2.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 KXZ46755.1 - 0.22 10.9 8.7 10 5.4 0.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KXZ46755.1 - 0.31 11.3 9.9 0.84 9.8 10.0 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 KXZ46755.1 - 0.47 10.5 7.6 0.53 10.4 6.4 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KXZ46755.1 - 2.9 7.7 6.8 25 4.7 6.3 2.4 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 KXZ46755.1 - 3.6 8.3 8.0 12 6.6 4.6 3.0 2 1 1 3 3 2 0 SlyX YabA PF06156.13 KXZ46755.1 - 3.7 8.2 5.6 5.9 7.6 2.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 KXZ46755.1 - 7.8 6.6 6.5 23 5.0 3.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KXZ46755.1 - 9.4 6.8 10.8 16 6.0 8.2 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Hexapep PF00132.24 KXZ46756.1 - 4.1e-07 29.5 1.6 0.0014 18.2 0.0 3.6 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ46756.1 - 0.0013 18.4 0.3 0.12 12.2 0.0 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXZ46756.1 - 0.075 12.0 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase DLH PF01738.18 KXZ46757.1 - 1.4e-33 116.3 0.3 1.5e-33 116.2 0.3 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXZ46757.1 - 1.1e-05 25.2 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KXZ46757.1 - 0.00038 20.5 2.5 0.15 11.9 0.2 2.5 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KXZ46757.1 - 0.00093 19.9 0.0 0.0028 18.3 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ46757.1 - 0.0066 15.7 0.2 0.08 12.2 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 HATPase_c_3 PF13589.6 KXZ46758.1 - 5.2e-13 49.0 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4407 PF14362.6 KXZ46758.1 - 0.00013 21.4 14.7 0.0017 17.8 3.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) HATPase_c PF02518.26 KXZ46758.1 - 0.0078 16.7 0.0 0.025 15.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2894 PF11445.8 KXZ46758.1 - 0.54 10.7 20.7 0.81 10.1 5.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) zf-C2H2_jaz PF12171.8 KXZ46759.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXZ46759.1 - 0.053 14.4 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXZ46759.1 - 0.055 13.5 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXZ46759.1 - 0.14 12.7 0.2 0.25 11.9 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KXZ46759.1 - 0.22 11.9 0.0 0.32 11.3 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF3730 PF12530.8 KXZ46761.1 - 4.1e-13 49.4 3.0 1.4e-12 47.7 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3730) SNARE PF05739.19 KXZ46761.1 - 7.3e-08 32.3 0.4 1.5e-07 31.3 0.4 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KXZ46761.1 - 3.9e-07 30.4 0.2 2e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 KXZ46761.1 - 0.00045 19.9 0.6 0.00087 19.0 0.6 1.4 1 0 0 1 1 1 1 Syntaxin DUF5345 PF17280.2 KXZ46761.1 - 0.06 13.3 2.6 0.045 13.7 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Spectrin PF00435.21 KXZ46761.1 - 0.18 12.3 0.7 0.38 11.2 0.7 1.5 1 0 0 1 1 1 0 Spectrin repeat DUF1073 PF06381.11 KXZ46761.1 - 0.27 10.0 4.6 0.083 11.7 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1073) DUF4253 PF14062.6 KXZ46761.1 - 0.31 11.2 1.9 0.49 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) HEAT PF02985.22 KXZ46761.1 - 0.49 10.8 23.0 0.23 11.8 0.2 5.8 5 0 0 5 5 4 0 HEAT repeat DLIC PF05783.11 KXZ46761.1 - 1.6 7.5 6.2 4.8 5.9 6.2 1.8 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ATG16 PF08614.11 KXZ46761.1 - 7.1 6.8 8.2 1.7 8.8 2.9 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DENN PF02141.21 KXZ46762.1 - 5.4e-21 75.4 0.0 7.3e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KXZ46762.1 - 6.4e-05 22.9 0.2 0.00016 21.6 0.0 1.7 2 0 0 2 2 2 1 dDENN domain Avl9 PF09794.9 KXZ46762.1 - 0.15 10.7 0.4 0.21 10.2 0.4 1.1 1 0 0 1 1 1 0 Transport protein Avl9 PDEase_I PF00233.19 KXZ46763.1 - 1.1e-70 238.0 0.0 1.7e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 KXZ46763.1 - 1.1e-06 28.7 0.0 4.3e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 CHASE domain Pyr_redox_3 PF13738.6 KXZ46764.1 - 1e-14 54.6 0.0 4.1e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ46764.1 - 1.6e-11 44.0 0.0 1.5e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ46764.1 - 5e-11 42.3 0.0 2e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXZ46764.1 - 8.7e-11 42.1 0.0 1.8e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KXZ46764.1 - 3.4e-06 26.9 0.0 0.0011 18.7 0.0 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXZ46764.1 - 0.0046 16.2 0.0 0.01 15.1 0.0 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXZ46764.1 - 0.014 14.1 0.1 0.21 10.2 0.0 2.6 3 1 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.6 KXZ46764.1 - 0.022 15.0 0.1 0.099 12.9 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXZ46764.1 - 0.12 13.0 0.2 3.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXZ46764.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MT-A70 PF05063.14 KXZ46765.1 - 1.9e-41 141.9 0.0 2.4e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 MT-A70 MgtE PF01769.16 KXZ46766.1 - 1.8e-25 89.7 7.3 1.8e-25 89.7 7.3 1.7 2 0 0 2 2 2 1 Divalent cation transporter Hydrolase_3 PF08282.12 KXZ46767.1 - 3.6e-37 128.5 0.0 1.4e-36 126.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXZ46767.1 - 2e-12 47.2 0.0 7.7e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KXZ46767.1 - 1.6e-08 35.1 0.5 7.9e-05 23.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXZ46767.1 - 0.0041 17.2 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ46767.1 - 0.007 16.8 0.4 1.8 9.0 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXZ46767.1 - 0.041 14.0 0.1 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KXZ46767.1 - 0.045 12.9 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase Hydrolase_3 PF08282.12 KXZ46768.1 - 1.7e-50 172.2 0.0 1.9e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXZ46768.1 - 2.2e-17 63.4 0.0 5.7e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KXZ46768.1 - 2.9e-08 34.2 0.6 4.4e-05 23.9 0.6 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXZ46768.1 - 0.013 15.6 0.1 0.054 13.6 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXZ46768.1 - 0.022 14.9 0.0 5.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KXZ46768.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase HAD PF12710.7 KXZ46768.1 - 0.092 13.1 0.2 2.4 8.5 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase RCC1_2 PF13540.6 KXZ46769.1 - 4.3e-32 109.2 38.9 7.1e-07 28.9 1.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXZ46769.1 - 1e-24 86.9 43.3 1e-07 32.4 0.7 7.6 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat LysM PF01476.20 KXZ46769.1 - 0.0056 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain ABC_tran PF00005.27 KXZ46770.1 - 6.3e-06 26.7 0.0 7.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter tRNA-synt_1 PF00133.22 KXZ46771.1 - 5.8e-20 71.1 0.0 8.7e-16 57.3 0.0 3.5 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXZ46771.1 - 1.5e-09 37.1 0.0 1.4e-08 33.9 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KXZ46771.1 - 1.3e-07 31.3 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Guanylate_cyc PF00211.20 KXZ46775.1 - 3.1e-52 176.9 0.0 6e-52 175.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 KXZ46775.1 - 0.0022 18.2 0.1 0.086 13.1 0.1 2.7 2 0 0 2 2 2 1 PAS fold ACBP PF00887.19 KXZ46775.1 - 0.074 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Acyl CoA binding protein IBR PF01485.21 KXZ46776.1 - 1.7e-10 41.0 20.0 7.5e-08 32.5 3.7 4.0 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXZ46776.1 - 0.0032 17.3 2.2 0.0032 17.3 2.2 5.2 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ46776.1 - 0.005 16.8 4.7 0.005 16.8 4.7 4.4 3 1 1 4 4 4 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXZ46776.1 - 0.005 16.8 3.7 0.005 16.8 3.7 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ46776.1 - 0.14 12.0 0.1 0.14 12.0 0.1 5.9 3 2 2 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Cript PF10235.9 KXZ46776.1 - 0.36 11.4 7.2 1.7 9.3 7.2 2.2 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT PRP1_N PF06424.12 KXZ46776.1 - 0.93 9.9 4.0 2.3 8.6 4.0 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Lipase_chap PF03280.14 KXZ46776.1 - 1.6 8.7 15.2 0.34 10.8 11.3 1.8 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein GYF PF02213.16 KXZ46778.1 - 5.6e-06 25.9 0.0 7.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 GYF domain PKD_channel PF08016.12 KXZ46779.1 - 1.1e-08 34.2 3.7 1.9e-08 33.4 3.7 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KXZ46779.1 - 1.7e-07 30.7 4.5 1.7e-07 30.7 4.5 1.9 2 0 0 2 2 2 1 Ion transport protein MFS_1 PF07690.16 KXZ46783.1 - 1.5e-14 53.8 45.1 1.5e-14 53.8 45.1 2.9 1 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXZ46783.1 - 0.0033 15.8 0.1 0.0033 15.8 0.1 1.9 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_2 PF00891.18 KXZ46784.1 - 1.9e-49 167.8 0.0 2.7e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXZ46784.1 - 1.1e-17 63.8 0.1 5.3e-08 32.7 0.0 2.6 3 0 0 3 3 3 2 Dimerisation domain Methyltransf_23 PF13489.6 KXZ46784.1 - 7.4e-07 29.1 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ46784.1 - 1.8e-05 25.3 0.0 4.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ46784.1 - 0.00091 19.9 0.0 0.002 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 KXZ46784.1 - 0.029 14.4 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 Dimerisation domain Rsm22 PF09243.10 KXZ46784.1 - 0.038 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Chlorophyllase2 PF12740.7 KXZ46785.1 - 3.7e-22 78.5 0.0 5.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXZ46785.1 - 2.4e-18 66.2 0.0 3.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 KXZ46785.1 - 0.00026 20.3 0.4 0.046 13.0 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KXZ46785.1 - 0.00057 18.5 0.0 0.51 8.8 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 KXZ46785.1 - 0.017 15.8 9.8 0.025 15.2 9.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXZ46785.1 - 0.023 14.6 1.1 0.024 14.5 0.1 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1057 PF06342.12 KXZ46785.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Homez PF11569.8 KXZ46785.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez 4HBT PF03061.22 KXZ46786.1 - 4.9e-26 90.9 4.4 1.8e-12 47.4 1.2 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DUF2807 PF10988.8 KXZ46787.1 - 1.4e-05 25.0 0.6 2.4e-05 24.2 0.5 1.4 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain DUF2807 PF10988.8 KXZ46788.1 - 1.6e-05 24.8 3.7 4e-05 23.5 3.7 1.6 1 0 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain Glyco_hydro_9 PF00759.19 KXZ46790.1 - 8.7e-64 216.5 0.0 1.2e-63 216.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF563 PF04577.14 KXZ46791.1 - 0.064 13.4 0.0 2.7 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF563) TTL PF03133.15 KXZ46792.1 - 2.4e-27 95.8 0.0 1e-15 57.7 0.0 2.3 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ46792.1 - 0.0006 19.1 0.0 0.00099 18.4 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ46792.1 - 0.03 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Haem_oxygenas_2 PF14518.6 KXZ46793.1 - 4.8e-25 88.3 0.4 7.4e-25 87.7 0.4 1.3 1 0 0 1 1 1 1 Iron-containing redox enzyme TcpQ PF10671.9 KXZ46793.1 - 0.13 12.4 0.4 0.93 9.7 0.1 2.2 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q TfoX_C PF04994.13 KXZ46793.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 TfoX C-terminal domain CLASP_N PF12348.8 KXZ46795.1 - 1.5e-12 47.6 3.0 0.0037 16.8 0.1 5.3 5 0 0 5 5 5 4 CLASP N terminal TAN PF11640.8 KXZ46795.1 - 9.6e-07 29.1 0.2 0.12 12.5 0.0 4.9 4 1 0 4 4 4 2 Telomere-length maintenance and DNA damage repair VHS PF00790.19 KXZ46795.1 - 0.04 13.8 4.0 8.2 6.3 0.0 5.5 7 0 0 7 7 7 0 VHS domain DCB PF16213.5 KXZ46795.1 - 0.085 12.5 0.4 0.67 9.6 0.1 2.6 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF2576 PF10845.8 KXZ46795.1 - 0.14 11.8 0.1 0.41 10.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) HEAT PF02985.22 KXZ46795.1 - 0.22 11.9 14.0 72 4.1 0.0 8.3 10 0 0 10 10 10 0 HEAT repeat NUC173 PF08161.12 KXZ46795.1 - 0.23 11.1 1.3 2.5 7.7 0.0 3.4 4 0 0 4 4 4 0 NUC173 domain DUF5538 PF17692.1 KXZ46796.1 - 0.055 13.5 1.4 0.31 11.1 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5538) Castor_Poll_mid PF06241.12 KXZ46801.1 - 0.0054 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel Citrate_synt PF00285.21 KXZ46804.1 - 2e-133 445.0 0.0 2.4e-133 444.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Kelch_4 PF13418.6 KXZ46805.1 - 1.6e-20 72.8 7.0 2.6e-07 30.5 0.1 6.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KXZ46805.1 - 7.2e-19 67.6 27.0 0.00011 22.4 0.1 7.9 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ46805.1 - 1.8e-13 50.2 0.3 0.022 14.7 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXZ46805.1 - 1.1e-08 34.5 5.5 0.15 11.6 0.1 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 KXZ46805.1 - 2.4e-08 34.0 6.0 0.028 14.7 0.0 6.4 6 2 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 KXZ46805.1 - 1.2e-06 28.2 9.7 0.25 11.4 0.1 7.0 7 1 0 7 7 7 2 Kelch motif Cytochrom_B561 PF03188.16 KXZ46805.1 - 1.9e-05 24.8 3.8 1.9e-05 24.8 3.8 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXZ46805.1 - 0.62 10.2 10.1 6 7.0 10.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) FIST_C PF10442.9 KXZ46806.1 - 0.022 14.7 1.3 0.029 14.3 1.3 1.2 1 0 0 1 1 1 0 FIST C domain DUF3040 PF11239.8 KXZ46806.1 - 2.5 8.4 11.4 3.9 7.8 10.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) PS_pyruv_trans PF04230.13 KXZ46807.1 - 1.8e-12 47.8 0.0 2.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase Josephin PF02099.17 KXZ46808.1 - 8.3e-17 61.8 0.0 7.4e-08 32.7 0.0 3.0 1 1 1 2 2 2 2 Josephin AMMECR1 PF01871.17 KXZ46809.1 - 6e-47 159.3 0.0 7.7e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 LSM PF01423.22 KXZ46810.1 - 1.4e-20 72.8 0.4 1.6e-20 72.6 0.4 1.1 1 0 0 1 1 1 1 LSM domain RicinB_lectin_2 PF14200.6 KXZ46811.1 - 4e-42 142.8 16.5 6.7e-17 62.0 0.1 5.1 2 2 3 5 5 5 5 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ46811.1 - 1.3e-33 115.9 4.6 1.7e-16 60.7 2.4 3.6 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ46811.1 - 9.3e-25 87.7 11.9 3.6e-23 82.5 10.9 3.1 1 1 1 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ46811.1 - 6.5e-07 29.1 3.6 0.077 12.6 0.0 3.3 1 1 2 3 3 3 3 Cytolethal distending toxin A/C domain EF-hand_1 PF00036.32 KXZ46812.1 - 6e-06 25.4 0.0 1.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ46812.1 - 0.00024 21.5 0.0 0.00045 20.6 0.0 1.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ46812.1 - 0.00025 20.7 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXZ46812.1 - 0.001 18.4 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ46812.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair Bac_GDH PF05088.12 KXZ46812.1 - 0.021 12.4 0.0 0.023 12.2 0.0 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase L27 PF02828.16 KXZ46812.1 - 0.04 13.7 0.5 0.063 13.1 0.5 1.3 1 0 0 1 1 1 0 L27 domain SNARE PF05739.19 KXZ46812.1 - 0.7 9.9 3.9 0.21 11.6 0.7 1.8 2 0 0 2 2 2 0 SNARE domain zf_CCCH_4 PF18345.1 KXZ46814.1 - 9.1e-07 28.7 5.7 1.7e-06 27.9 5.7 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXZ46814.1 - 1.9e-06 27.6 4.0 3.4e-06 26.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXZ46814.1 - 5.6e-05 22.8 5.4 0.00011 21.8 5.4 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Ank PF00023.30 KXZ46814.1 - 6.9e-05 23.1 0.4 0.00029 21.2 0.4 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KXZ46814.1 - 0.013 15.9 0.1 0.048 14.2 0.1 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 KXZ46814.1 - 0.022 15.3 0.6 0.07 13.7 0.0 2.2 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) zf-CCCH_2 PF14608.6 KXZ46814.1 - 0.026 15.0 2.2 0.048 14.1 2.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger EIF4E-T PF10477.9 KXZ46814.1 - 0.042 12.7 11.9 0.083 11.7 11.9 1.4 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Torus PF16131.5 KXZ46814.1 - 0.045 14.5 0.2 0.045 14.5 0.2 2.6 2 0 0 2 2 2 0 Torus domain Ank_5 PF13857.6 KXZ46814.1 - 0.1 13.0 0.1 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) APH PF01636.23 KXZ46815.1 - 1.1e-05 25.5 1.5 0.021 14.8 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ46815.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 KXZ46815.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PEMT PF04191.13 KXZ46817.1 - 5.1e-14 52.6 0.0 7.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KXZ46817.1 - 3.1e-09 37.1 0.1 5.1e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KXZ46817.1 - 0.00026 20.6 0.1 0.00035 20.2 0.1 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KXZ46817.1 - 0.0071 15.9 0.1 0.0094 15.5 0.1 1.3 1 1 0 1 1 1 1 NnrU protein FAD_binding_6 PF00970.24 KXZ46818.1 - 1.6e-32 111.8 0.0 2.6e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXZ46818.1 - 4.2e-24 85.3 0.0 1.1e-23 84.0 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXZ46818.1 - 0.016 15.3 0.4 0.11 12.6 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXZ46818.1 - 0.034 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Ni_hydr_CYTB PF01292.20 KXZ46818.1 - 0.034 13.8 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Rhomboid PF01694.22 KXZ46819.1 - 7.4e-18 65.0 13.8 7.4e-18 65.0 13.8 2.1 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.15 KXZ46819.1 - 0.031 14.2 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 Der1-like family CLTH PF10607.9 KXZ46821.1 - 1.7e-29 102.6 0.0 2.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.15 KXZ46821.1 - 0.031 14.5 0.0 0.095 12.9 0.0 1.8 2 0 0 2 2 2 0 U-box domain SANT_DAMP1_like PF16282.5 KXZ46822.1 - 1.9e-30 104.9 1.2 3.1e-30 104.2 1.2 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Rrn6 PF10214.9 KXZ46822.1 - 0.1 11.1 0.8 0.15 10.5 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor zf_CCCH_4 PF18345.1 KXZ46823.1 - 0.011 15.8 0.9 0.011 15.8 0.9 3.2 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH PF00642.24 KXZ46823.1 - 0.029 14.3 0.7 0.029 14.3 0.7 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF647 PF04884.14 KXZ46824.1 - 1.7e-26 93.4 5.7 2.4e-26 92.9 5.7 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Methyltransf_21 PF05050.12 KXZ46826.1 - 1.8e-11 44.3 0.0 2.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 KXZ46827.1 - 2.1e-10 40.9 0.0 2.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 KXZ46828.1 - 7.6e-10 39.1 0.0 9.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain PHD PF00628.29 KXZ46829.1 - 1.6e-08 34.3 6.2 1.6e-08 34.3 6.2 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KXZ46829.1 - 0.006 16.1 1.0 0.012 15.1 1.0 1.5 1 0 0 1 1 1 1 PHD-finger Guanylate_cyc PF00211.20 KXZ46830.1 - 2e-11 43.8 0.0 2.3e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SBP_bac_1 PF01547.25 KXZ46830.1 - 1.5e-05 25.1 0.0 4.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein IMS PF00817.20 KXZ46831.1 - 2.8e-73 244.9 0.0 4.4e-37 127.4 0.0 3.4 2 1 0 2 2 2 2 impB/mucB/samB family Amidohydro_1 PF01979.20 KXZ46831.1 - 1.2e-46 159.6 0.0 2.5e-46 158.6 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family IMS_C PF11799.8 KXZ46831.1 - 3.5e-14 53.5 0.0 4.2e-09 37.1 0.0 2.7 2 0 0 2 2 2 2 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXZ46831.1 - 4.3e-07 29.9 0.0 0.00013 22.0 0.0 2.6 2 0 0 2 2 2 2 IMS family HHH motif NIR_SIR_ferr PF03460.17 KXZ46831.1 - 0.028 14.3 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Amidohydro_1 PF01979.20 KXZ46833.1 - 4.7e-48 164.3 0.0 6.7e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXZ46833.1 - 2.1e-09 37.4 0.0 2.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family DUF2461 PF09365.10 KXZ46833.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) NIR_SIR_ferr PF03460.17 KXZ46833.1 - 0.074 12.9 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain AAA_6 PF12774.7 KXZ46834.1 - 3e-125 417.5 0.0 8.4e-70 235.3 0.0 2.9 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ46834.1 - 2.7e-111 372.5 11.0 2.7e-111 372.5 11.0 3.8 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXZ46834.1 - 1.8e-92 309.3 0.0 1.1e-91 306.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KXZ46834.1 - 3.2e-84 282.8 0.1 2.3e-83 279.9 0.0 2.5 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KXZ46834.1 - 9.9e-84 279.9 0.7 2.4e-83 278.6 0.7 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 KXZ46834.1 - 3.8e-82 276.1 20.9 7.1e-82 275.2 20.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 KXZ46834.1 - 2.1e-64 216.4 0.3 6e-59 198.6 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ46834.1 - 2.3e-45 154.3 0.0 9.4e-44 149.1 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Kelch_4 PF13418.6 KXZ46834.1 - 7.4e-38 128.3 14.3 2.2e-07 30.8 0.0 10.0 10 1 1 11 11 10 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ46834.1 - 2.7e-36 123.0 2.0 5e-05 23.2 0.0 9.6 11 0 0 11 11 10 7 Kelch motif Dynein_heavy PF03028.15 KXZ46834.1 - 3.5e-36 123.9 0.0 1.8e-33 115.2 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Kelch_1 PF01344.25 KXZ46834.1 - 1.9e-28 97.8 8.0 0.0021 17.6 0.1 10.3 9 0 0 9 9 9 6 Kelch motif Dynein_AAA_lid PF17852.1 KXZ46834.1 - 3e-28 98.5 0.0 9.2e-28 96.9 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Kelch_2 PF07646.15 KXZ46834.1 - 5.4e-28 95.9 15.1 0.0005 19.9 0.1 10.0 11 0 0 11 11 8 5 Kelch motif AAA_lid_1 PF17857.1 KXZ46834.1 - 5.3e-27 94.0 0.3 2.1e-26 92.0 0.3 2.1 1 0 0 1 1 1 1 AAA+ lid domain Kelch_3 PF13415.6 KXZ46834.1 - 4.8e-24 84.1 20.1 2.5e-05 24.4 0.0 10.3 11 0 0 11 11 11 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ46834.1 - 4.3e-19 68.1 11.0 0.0016 18.7 0.0 10.2 10 2 2 12 12 10 3 Kelch motif AAA_5 PF07728.14 KXZ46834.1 - 9.8e-19 67.7 0.0 1.9e-07 31.2 0.0 5.8 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Filamin PF00630.19 KXZ46834.1 - 4.4e-17 62.8 0.0 1e-16 61.6 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat AAA PF00004.29 KXZ46834.1 - 3.3e-06 27.6 4.9 7.9 6.9 0.0 5.5 6 0 0 6 6 4 0 ATPase family associated with various cellular activities (AAA) TIG PF01833.24 KXZ46834.1 - 7.4e-06 26.0 0.1 5.3e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain AAA_16 PF13191.6 KXZ46834.1 - 0.00022 21.7 6.5 35 4.7 0.0 6.6 6 0 0 6 6 5 0 AAA ATPase domain AAA_22 PF13401.6 KXZ46834.1 - 0.00026 21.3 0.2 1.9 8.8 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KXZ46834.1 - 0.0015 19.0 2.7 4.6 7.8 0.0 4.5 4 0 0 4 4 4 1 AAA domain TsaE PF02367.17 KXZ46834.1 - 0.0039 17.2 0.6 8.5 6.4 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXZ46834.1 - 0.0068 16.8 1.7 4.9 7.6 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_19 PF13245.6 KXZ46834.1 - 0.026 14.9 2.0 7.2 6.9 0.1 3.9 3 0 0 3 3 3 0 AAA domain Cut8 PF08559.10 KXZ46834.1 - 0.08 12.5 0.1 3 7.4 0.1 2.5 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein AAA_33 PF13671.6 KXZ46834.1 - 1.2 9.3 2.8 26 5.0 0.1 3.8 4 0 0 4 4 4 0 AAA domain FlaC_arch PF05377.11 KXZ46834.1 - 5.7 7.4 6.9 73 3.9 0.5 4.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Kinesin PF00225.23 KXZ46835.1 - 2.3e-106 355.5 0.0 2.3e-106 355.5 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ46835.1 - 6.5e-43 146.2 0.0 1.9e-42 144.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding UPF0184 PF03670.13 KXZ46835.1 - 0.046 14.1 2.8 0.13 12.7 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Trep_dent_lipo PF09710.10 KXZ46835.1 - 1 8.2 3.4 1.7 7.5 3.4 1.4 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Golgin_A5 PF09787.9 KXZ46835.1 - 1.1 8.7 51.3 0.24 10.8 27.0 3.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 OmpA PF00691.20 KXZ46835.1 - 1.5 9.2 8.7 0.33 11.3 3.9 2.4 2 0 0 2 2 2 0 OmpA family Spc7 PF08317.11 KXZ46835.1 - 1.9 7.3 52.6 0.04 12.8 18.3 4.0 1 1 2 3 3 3 0 Spc7 kinetochore protein UreE_C PF05194.12 KXZ46835.1 - 2.7 8.6 5.0 15 6.1 0.4 3.0 1 1 1 2 2 2 0 UreE urease accessory protein, C-terminal domain DUF3584 PF12128.8 KXZ46835.1 - 5.5 4.4 54.0 0.084 10.4 43.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Vta1 PF04652.16 KXZ46837.1 - 3.3e-40 137.4 0.2 4.7e-40 136.9 0.2 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KXZ46837.1 - 9e-16 57.3 0.6 1.9e-15 56.3 0.6 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain Pkinase PF00069.25 KXZ46839.1 - 4.4e-30 104.9 0.0 2.1e-23 83.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46839.1 - 9.2e-25 87.4 0.0 1.2e-18 67.4 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Peptidase_M11 PF05548.11 KXZ46840.1 - 2.4e-36 125.5 0.0 3.5e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 NifU PF01106.17 KXZ46841.1 - 0.041 14.0 0.1 0.091 12.9 0.1 1.5 1 0 0 1 1 1 0 NifU-like domain Cation_efflux PF01545.21 KXZ46843.1 - 4.3e-20 72.3 1.8 6.9e-20 71.6 1.8 1.2 1 0 0 1 1 1 1 Cation efflux family TPR_9 PF13371.6 KXZ46843.1 - 5e-08 33.0 9.7 7.1e-08 32.5 6.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Transglut_core2 PF13369.6 KXZ46843.1 - 0.0017 18.0 0.0 0.032 13.8 0.0 2.3 1 1 0 1 1 1 1 Transglutaminase-like superfamily TcpQ PF10671.9 KXZ46843.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Ank_2 PF12796.7 KXZ46845.1 - 5.3e-22 78.2 13.7 9.6e-05 22.9 0.9 6.5 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46845.1 - 8.9e-11 42.1 12.7 0.023 15.3 0.2 7.7 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46845.1 - 8.5e-08 31.9 17.8 14 6.6 0.0 11.0 13 0 0 13 13 13 3 Ankyrin repeat Ank_5 PF13857.6 KXZ46845.1 - 2.6e-07 30.8 18.4 1.6 9.1 0.0 7.5 6 1 2 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46845.1 - 0.092 13.2 38.1 0.7 10.4 0.3 10.0 10 1 1 11 11 11 0 Ankyrin repeat DUF4128 PF13554.6 KXZ46845.1 - 0.14 12.2 0.7 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage related domain of unknown function PEMT PF04191.13 KXZ46846.1 - 2.2e-11 44.1 0.0 3.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KXZ46846.1 - 2.3e-08 34.3 0.0 4.2e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KXZ46846.1 - 0.00029 20.4 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) LtrA PF06772.11 KXZ46846.1 - 0.01 15.1 0.2 0.014 14.6 0.2 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) NnrU PF07298.11 KXZ46846.1 - 0.046 13.2 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 NnrU protein TTL PF03133.15 KXZ46847.1 - 5e-68 229.4 0.0 6.4e-67 225.8 0.0 2.2 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ46847.1 - 0.00024 20.4 1.5 0.0008 18.7 0.0 2.5 3 0 0 3 3 3 1 YheC/D like ATP-grasp zf-C3HC4_3 PF13920.6 KXZ46848.1 - 2e-09 37.1 4.9 2.9e-09 36.6 4.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ46848.1 - 2.7e-09 37.2 7.6 4.5e-09 36.5 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXZ46848.1 - 5.8e-06 26.2 5.6 1.1e-05 25.4 5.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ46848.1 - 8.3e-06 25.6 8.5 1.3e-05 24.9 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ46848.1 - 2.6e-05 24.1 5.1 4.4e-05 23.3 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ46848.1 - 3.4e-05 23.6 7.2 5.3e-05 23.0 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ46848.1 - 0.00035 20.8 4.1 0.00035 20.8 4.1 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXZ46848.1 - 0.0066 16.3 9.2 0.064 13.1 9.5 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KXZ46848.1 - 0.17 11.8 2.3 0.27 11.2 2.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.14 KXZ46848.1 - 0.33 10.6 4.9 0.07 12.8 1.2 1.7 2 0 0 2 2 2 0 P-11 zinc finger TackOD1 PF18551.1 KXZ46848.1 - 0.41 10.3 2.0 0.6 9.8 2.0 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-C3HC4_4 PF15227.6 KXZ46848.1 - 1.1 9.5 9.0 1.9 8.7 9.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXZ46848.1 - 4.2 7.2 5.5 8.4 6.3 5.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA_16 PF13191.6 KXZ46850.1 - 0.0064 16.9 9.5 0.94 9.8 0.0 5.0 3 1 0 3 3 3 2 AAA ATPase domain DUF445 PF04286.12 KXZ46850.1 - 0.47 10.2 5.7 1 9.1 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FliG_C PF01706.16 KXZ46850.1 - 0.78 10.0 2.9 2.3 8.5 2.9 1.8 1 0 0 1 1 1 0 FliG C-terminal domain SLX9 PF15341.6 KXZ46853.1 - 1.3e-16 61.2 4.5 1.3e-16 61.2 4.5 1.6 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 F-box-like PF12937.7 KXZ46855.1 - 4.5e-08 32.9 0.1 4.5e-08 32.9 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXZ46855.1 - 5.2e-06 26.2 0.0 9.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXZ46855.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 F-box Chorismate_synt PF01264.21 KXZ46856.1 - 3.5e-141 469.6 1.3 4e-141 469.4 1.3 1.0 1 0 0 1 1 1 1 Chorismate synthase DNA_pol_A_exo1 PF01612.20 KXZ46857.1 - 1.6e-27 96.4 0.0 1.8e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease HRDC PF00570.23 KXZ46857.1 - 1.3e-06 28.3 0.4 3.3e-06 27.0 0.4 1.7 1 0 0 1 1 1 1 HRDC domain TRAPP PF04051.16 KXZ46858.1 - 2.8e-36 124.4 0.0 3.3e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DDE_Tnp_ISAZ013 PF07592.11 KXZ46858.1 - 0.13 11.2 0.0 6.8 5.6 0.0 2.0 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain Myb_DNA-binding PF00249.31 KXZ46859.1 - 2.9e-19 69.0 2.4 3.8e-09 36.6 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ46859.1 - 6.4e-12 45.5 0.0 2.2e-06 27.8 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Cupin_3 PF05899.12 KXZ46861.1 - 1.7e-10 40.4 0.3 1.8e-10 40.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KXZ46861.1 - 0.047 13.4 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 Cupin domain Pirin PF02678.16 KXZ46861.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Pirin SGT1 PF07093.11 KXZ46863.1 - 1.3e-07 30.5 7.1 0.00021 19.9 0.0 2.8 2 1 0 2 2 2 2 SGT1 protein SDA1 PF05285.12 KXZ46863.1 - 0.2 11.1 12.3 0.27 10.6 12.3 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXZ46863.1 - 0.37 10.1 12.5 0.49 9.7 12.5 1.3 1 0 0 1 1 1 0 BUD22 LAX PF15681.5 KXZ46863.1 - 0.65 8.8 4.3 1.2 7.9 4.3 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X TFIIF_alpha PF05793.12 KXZ46863.1 - 0.98 7.9 12.5 1.2 7.6 12.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KXZ46863.1 - 2 6.5 12.9 2.5 6.2 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXZ46863.1 - 8.3 4.6 9.9 11 4.2 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein XPG_I PF00867.18 KXZ46864.1 - 3.3e-29 101.1 0.0 6.5e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXZ46864.1 - 6.4e-29 100.4 0.0 1.1e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KXZ46864.1 - 6.8e-06 26.6 0.0 2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold SGT1 PF07093.11 KXZ46865.1 - 8e-69 232.6 0.0 1.9e-68 231.3 0.0 1.5 1 1 0 1 1 1 1 SGT1 protein NdhO PF11910.8 KXZ46865.1 - 0.21 11.8 0.0 0.43 10.8 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O tRNA-synt_1b PF00579.25 KXZ46866.1 - 9e-69 232.0 0.0 1.2e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ion_trans PF00520.31 KXZ46867.1 - 2.5e-09 36.7 18.7 3.8e-07 29.6 18.7 2.2 1 1 0 1 1 1 1 Ion transport protein WD40 PF00400.32 KXZ46867.1 - 5.3e-09 36.6 7.1 0.00027 21.6 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ46867.1 - 0.00088 19.5 0.4 4.6 7.6 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.7 KXZ46867.1 - 0.12 12.9 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) PKD_channel PF08016.12 KXZ46867.1 - 1.2 7.7 12.8 2.7 6.6 12.8 1.6 1 1 0 1 1 1 0 Polycystin cation channel DUF393 PF04134.12 KXZ46868.1 - 4.1e-24 86.1 0.0 5.2e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Anti-TRAP PF15777.5 KXZ46869.1 - 0.028 14.4 0.6 0.063 13.2 0.6 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_CXXCXGXG PF00684.19 KXZ46869.1 - 0.52 10.7 2.4 1.4 9.4 2.4 1.5 1 1 0 1 1 1 0 DnaJ central domain Orexin PF02072.15 KXZ46870.1 - 1.2 9.1 10.6 0.46 10.4 0.2 3.7 3 0 0 3 3 3 0 Prepro-orexin TatC PF00902.18 KXZ46871.1 - 1.7e-59 201.1 11.9 2e-59 200.9 11.9 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF2919 PF11143.8 KXZ46871.1 - 0.43 10.9 5.7 0.097 13.0 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) FtsJ PF01728.19 KXZ46872.1 - 5.3e-66 222.1 0.0 6.4e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF4586 PF15239.6 KXZ46873.1 - 8.1e-18 65.6 7.6 4.1e-17 63.3 7.6 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) Totivirus_coat PF05518.11 KXZ46873.1 - 0.065 11.3 2.0 0.085 10.9 2.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_M11 PF05548.11 KXZ46874.1 - 2e-38 132.3 0.0 2.9e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_S8 PF00082.22 KXZ46875.1 - 1.3e-22 80.5 0.5 2.2e-22 79.7 0.5 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 KXZ46876.1 - 0.0001 21.7 0.1 0.00014 21.2 0.1 1.2 1 0 0 1 1 1 1 Subtilase family PAS_4 PF08448.10 KXZ46877.1 - 6.5e-12 45.7 0.2 0.00042 20.5 0.0 5.3 5 0 0 5 5 5 3 PAS fold PAS_9 PF13426.7 KXZ46877.1 - 7.1e-10 39.1 0.0 0.0002 21.6 0.0 3.9 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 KXZ46877.1 - 1.5e-07 31.4 0.0 0.00072 19.5 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KXZ46877.1 - 6.1e-05 22.9 0.1 0.0038 17.2 0.0 3.2 3 0 0 3 3 3 1 PAS domain DUF4381 PF14316.6 KXZ46877.1 - 3 8.1 7.5 4.7 7.4 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PP-binding PF00550.25 KXZ46878.1 - 8.4e-14 51.7 0.1 1.5e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXZ46878.1 - 0.00042 20.5 0.1 0.00065 19.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L12_N PF16320.5 KXZ46878.1 - 0.0011 18.6 0.4 0.0022 17.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_L50 PF10501.9 KXZ46878.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.4 1 1 0 1 1 1 0 Ribosomal subunit 39S DUF1493 PF07377.12 KXZ46878.1 - 0.14 12.6 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) MAT1 PF06391.13 KXZ46879.1 - 9.4e-20 71.3 1.8 1.2e-19 71.0 1.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Ferritin PF00210.24 KXZ46879.1 - 0.047 13.6 0.4 0.065 13.2 0.4 1.2 1 0 0 1 1 1 0 Ferritin-like domain Pkinase PF00069.25 KXZ46880.1 - 6.7e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46880.1 - 0.00073 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_2 PF13185.6 KXZ46880.1 - 0.0014 18.9 0.0 0.057 13.7 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 KXZ46880.1 - 0.0018 18.9 0.1 0.088 13.4 0.1 2.4 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KXZ46880.1 - 0.015 15.6 0.0 2.7 8.4 0.0 2.6 2 0 0 2 2 2 0 GAF domain Use1 PF09753.9 KXZ46881.1 - 8.6e-09 35.5 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.6 KXZ46881.1 - 0.0071 15.7 0.7 0.0097 15.3 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Amnionless PF14828.6 KXZ46881.1 - 0.16 10.8 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Amnionless TMEM174 PF15029.6 KXZ46881.1 - 0.19 11.4 0.1 0.29 10.8 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 174 WD40 PF00400.32 KXZ46882.1 - 5.3e-68 223.3 39.3 7.8e-08 32.9 0.9 13.7 14 0 0 14 14 14 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ46882.1 - 7.5e-14 51.8 0.0 0.0015 18.8 0.0 6.3 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain APAF1_C PF17908.1 KXZ46882.1 - 4.4e-07 30.0 0.0 6.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 APAF-1 helical domain Ge1_WD40 PF16529.5 KXZ46882.1 - 0.00033 19.7 4.2 2.2 7.1 0.2 5.3 5 1 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXZ46882.1 - 0.25 9.9 14.1 9.9 4.7 0.1 6.6 3 3 3 7 7 7 0 Nucleoporin Nup120/160 Ecl1 PF12855.7 KXZ46882.1 - 0.87 10.7 9.1 1.5 10.0 9.1 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins SoxZ PF08770.11 KXZ46883.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ DHC_N1 PF08385.12 KXZ46884.1 - 0.27 9.8 0.1 0.31 9.6 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Collagen_mid PF15984.5 KXZ46885.1 - 0.0067 16.2 1.4 0.009 15.8 1.4 1.2 1 0 0 1 1 1 1 Bacterial collagen, middle region DUF3533 PF12051.8 KXZ46885.1 - 0.054 12.4 0.6 0.067 12.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DHC_N1 PF08385.12 KXZ46885.1 - 0.082 11.5 0.9 0.099 11.3 0.9 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Minor_tail_Z PF06763.11 KXZ46885.1 - 0.1 12.4 2.4 0.18 11.6 2.4 1.4 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) VCX_VCY PF15231.6 KXZ46885.1 - 0.16 12.7 3.1 0.27 11.9 3.1 1.3 1 0 0 1 1 1 0 Variable charge X/Y family TrbI PF03743.14 KXZ46885.1 - 0.33 10.8 4.8 0.51 10.1 4.8 1.3 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein TFIIA PF03153.13 KXZ46885.1 - 1.9 8.4 9.8 1.9 8.4 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_4 PF13637.6 KXZ46886.1 - 6.5e-17 61.7 5.8 7.2e-05 23.3 0.1 7.2 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ46886.1 - 2e-10 41.1 0.0 0.28 11.8 0.0 5.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ46886.1 - 8.7e-08 31.9 0.1 1.3e+02 3.6 0.0 9.2 11 0 0 11 11 11 0 Ankyrin repeat F-box PF00646.33 KXZ46886.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF3493 PF11998.8 KXZ46886.1 - 0.89 9.8 4.7 13 6.0 0.1 3.4 2 1 1 3 3 3 0 Low psii accumulation1 / Rep27 Ank_5 PF13857.6 KXZ46886.1 - 1 9.8 5.4 93 3.5 0.0 5.2 5 2 2 7 7 7 0 Ankyrin repeats (many copies) RLL PF10036.9 KXZ46887.1 - 9.7e-28 97.7 0.0 1.1e-27 97.5 0.0 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Kazal_2 PF07648.15 KXZ46888.1 - 1.2e-20 73.3 50.2 2.8e-06 27.4 11.4 5.8 3 1 1 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KXZ46888.1 - 1.5e-15 56.9 62.7 1.1e-05 25.3 0.5 6.0 5 1 1 6 6 6 4 Kazal-type serine protease inhibitor domain Hist_deacetyl PF00850.19 KXZ46890.1 - 9.6e-45 153.4 0.0 1.4e-44 152.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Myb_DNA-bind_6 PF13921.6 KXZ46891.1 - 4.5e-25 87.7 8.0 1e-16 60.9 0.3 4.2 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXZ46891.1 - 2.9e-22 78.6 17.6 1e-11 44.8 1.0 5.0 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXZ46891.1 - 0.0019 18.5 6.2 2.2 8.7 0.1 4.7 4 1 0 4 4 4 1 Myb/SANT-like DNA-binding domain AAA_lid_11 PF18198.1 KXZ46891.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain SLIDE PF09111.10 KXZ46891.1 - 0.093 12.8 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 SLIDE APG6_N PF17675.1 KXZ46892.1 - 0.0089 16.6 13.1 0.89 10.1 2.3 4.3 5 0 0 5 5 5 2 Apg6 coiled-coil region HAP1_N PF04849.13 KXZ46892.1 - 0.11 11.7 0.0 0.11 11.7 0.0 2.4 4 0 0 4 4 4 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 KXZ46892.1 - 0.35 10.2 30.2 0.45 9.8 11.1 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4407) GAS PF13851.6 KXZ46892.1 - 8.4 5.7 16.7 3.3 7.0 0.3 4.3 5 0 0 5 5 5 0 Growth-arrest specific micro-tubule binding GldM_N PF12081.8 KXZ46893.1 - 1.3 9.1 11.9 0.47 10.5 6.4 2.3 1 1 1 2 2 2 0 GldM N-terminal domain Pcc1 PF09341.10 KXZ46893.1 - 2.8 8.1 6.3 16 5.8 6.3 2.4 1 1 0 1 1 1 0 Transcription factor Pcc1 RNA_lig_T4_1 PF09511.10 KXZ46893.1 - 7.5 6.3 6.1 10 5.9 5.5 1.6 1 1 0 1 1 1 0 RNA ligase DUF2870 PF11069.8 KXZ46894.1 - 5.9e-41 138.8 2.5 1.1e-40 138.0 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) XRCC4 PF06632.12 KXZ46895.1 - 1.6e-05 23.9 2.9 1.6e-05 23.9 2.9 1.6 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 IHO1 PF15771.5 KXZ46895.1 - 0.0032 16.3 4.7 0.0041 16.0 4.7 1.1 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 CENP-H PF05837.12 KXZ46895.1 - 0.012 16.0 7.5 0.012 16.0 7.5 1.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DHR10 PF18595.1 KXZ46895.1 - 0.023 14.8 15.4 0.18 11.9 9.0 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FapA PF03961.13 KXZ46895.1 - 0.028 13.0 0.5 0.034 12.8 0.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_23 PF13476.6 KXZ46895.1 - 0.031 14.8 1.5 0.036 14.6 1.5 1.2 1 0 0 1 1 1 0 AAA domain UPF0449 PF15136.6 KXZ46895.1 - 0.035 14.6 4.5 2.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 I_LWEQ PF01608.17 KXZ46895.1 - 0.041 14.1 9.5 0.23 11.7 9.5 1.9 1 1 0 1 1 1 0 I/LWEQ domain DUF4407 PF14362.6 KXZ46895.1 - 0.042 13.2 10.1 0.14 11.5 5.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 KXZ46895.1 - 0.046 14.3 14.1 0.12 13.0 7.1 2.5 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.11 KXZ46895.1 - 0.067 13.3 7.7 0.091 12.9 7.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KXZ46895.1 - 0.079 11.8 10.5 0.1 11.4 10.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KXZ46895.1 - 0.11 12.1 2.5 0.14 11.7 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_I PF06008.14 KXZ46895.1 - 0.12 12.1 10.6 1.8 8.2 0.1 2.1 1 1 1 2 2 2 0 Laminin Domain I FlxA PF14282.6 KXZ46895.1 - 0.14 12.2 10.4 0.23 11.5 10.4 1.3 1 0 0 1 1 1 0 FlxA-like protein Sugarporin_N PF11471.8 KXZ46895.1 - 0.16 11.9 6.2 0.47 10.4 6.2 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ATG16 PF08614.11 KXZ46895.1 - 0.27 11.4 14.3 0.6 10.3 14.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4375 PF14300.6 KXZ46895.1 - 0.41 10.9 3.5 42 4.4 3.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) TMPIT PF07851.13 KXZ46895.1 - 0.42 9.8 4.1 0.53 9.5 4.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3584 PF12128.8 KXZ46895.1 - 0.63 7.5 9.5 0.75 7.2 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Macoilin PF09726.9 KXZ46895.1 - 0.81 8.2 7.3 1 7.8 7.3 1.0 1 0 0 1 1 1 0 Macoilin family COG2 PF06148.11 KXZ46895.1 - 0.85 9.7 4.8 12 6.0 1.6 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC PF04632.12 KXZ46895.1 - 1.5 7.3 3.7 1.9 6.9 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 KXZ46895.1 - 1.7 8.7 18.4 23 5.0 18.3 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 KXZ46895.1 - 1.7 9.1 4.1 29 5.2 0.5 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 KXZ46895.1 - 1.8 6.4 3.3 2.4 6.0 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 KXZ46895.1 - 1.9 8.9 15.7 3.3 8.1 11.8 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.9 KXZ46895.1 - 4.4 6.3 9.1 14 4.6 9.8 1.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Swi5 PF07061.11 KXZ46895.1 - 5.7 7.1 11.0 3.9 7.6 4.3 2.3 2 0 0 2 2 2 0 Swi5 C2 PF00168.30 KXZ46896.1 - 3.6e-15 56.1 0.0 9.9e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain FliJ PF02050.16 KXZ46897.1 - 0.073 13.3 5.6 2.5 8.3 5.7 2.3 3 0 0 3 3 3 0 Flagellar FliJ protein CCDC-167 PF15188.6 KXZ46897.1 - 0.6 10.5 2.0 1.3 9.4 2.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 bPH_2 PF03703.14 KXZ46898.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain ELYS PF13934.6 KXZ46899.1 - 3.5e-20 72.9 0.3 3.6e-19 69.6 0.0 2.3 2 0 0 2 2 2 1 Nuclear pore complex assembly Pescadillo_N PF06732.11 KXZ46900.1 - 1.4e-112 375.7 0.2 1.4e-112 375.7 0.2 1.5 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KXZ46900.1 - 0.0084 16.5 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain CDC45 PF02724.14 KXZ46900.1 - 0.015 13.6 28.5 0.0071 14.7 1.3 2.8 3 0 0 3 3 3 0 CDC45-like protein UPF0225 PF17775.1 KXZ46901.1 - 1.8e-05 25.5 0.0 2.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain Pkinase PF00069.25 KXZ46902.1 - 9.2e-28 97.3 0.0 1.5e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46902.1 - 9.8e-13 48.0 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46902.1 - 2.4e-05 23.8 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ46902.1 - 0.099 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GST_C_3 PF14497.6 KXZ46903.1 - 1.2e-16 60.7 0.0 2.1e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXZ46903.1 - 1.9e-11 44.1 0.0 3.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ46903.1 - 2.2e-07 31.0 0.0 5.3e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXZ46903.1 - 1.4e-05 25.4 0.0 2.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ46903.1 - 2e-05 24.5 0.0 4.7e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXZ46903.1 - 0.00022 21.5 0.0 0.00052 20.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain CHASE3 PF05227.13 KXZ46903.1 - 0.039 13.9 0.1 0.055 13.4 0.1 1.1 1 0 0 1 1 1 0 CHASE3 domain GST_C_3 PF14497.6 KXZ46904.1 - 5.6e-14 52.1 0.0 8.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXZ46904.1 - 1.6e-11 44.4 0.0 2.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXZ46904.1 - 2.2e-07 31.2 0.0 3.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ46904.1 - 3.6e-06 27.1 0.0 5.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXZ46904.1 - 0.00042 20.6 0.0 0.00069 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ46904.1 - 0.0015 18.5 0.0 0.0037 17.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KXZ46904.1 - 0.003 17.4 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain CHASE3 PF05227.13 KXZ46904.1 - 0.0072 16.2 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 CHASE3 domain Type_III_YscX PF09474.10 KXZ46904.1 - 0.13 12.5 0.2 0.2 11.9 0.2 1.2 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) RPN7 PF10602.9 KXZ46904.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 XendoU PF09412.10 KXZ46905.1 - 2.4e-100 335.1 0.0 2.8e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 KXZ46905.1 - 0.086 13.2 0.1 0.59 10.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial EndoU nuclease DPBB_1 PF03330.18 KXZ46906.1 - 1.7e-07 31.4 0.0 2.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase TackOD1 PF18551.1 KXZ46906.1 - 0.0088 15.7 0.2 0.01 15.5 0.2 1.2 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 DPBB_1 PF03330.18 KXZ46907.1 - 3.4e-11 43.3 0.1 8.2e-11 42.0 0.1 1.7 1 0 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KXZ46907.1 - 1.1e-05 25.3 0.1 6.6e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Pollen allergen Barwin PF00967.17 KXZ46907.1 - 0.04 13.8 0.2 0.078 12.8 0.2 1.4 1 0 0 1 1 1 0 Barwin family GrpE PF01025.19 KXZ46908.1 - 3.5e-39 134.1 2.6 3.5e-39 134.1 2.6 5.4 4 1 0 4 4 4 1 GrpE C2-C2_1 PF11618.8 KXZ46909.1 - 6.9e-37 126.7 0.0 4.4e-36 124.1 0.0 2.4 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 EF-hand_7 PF13499.6 KXZ46909.1 - 2.8e-19 69.3 4.2 4.1e-11 43.2 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ46909.1 - 1.1e-14 53.1 1.7 5.3e-05 22.8 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KXZ46909.1 - 7.3e-14 50.2 1.9 9.7e-05 21.6 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KXZ46909.1 - 5.9e-09 35.0 6.0 8.9e-05 21.8 0.1 3.8 3 0 0 3 3 3 2 EF hand C2 PF00168.30 KXZ46909.1 - 2.7e-08 34.0 0.0 6.4e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 C2 domain EF-hand_8 PF13833.6 KXZ46909.1 - 0.0005 19.9 6.0 0.023 14.5 0.1 4.2 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXZ46909.1 - 0.00077 19.8 0.2 0.16 12.3 0.0 3.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RPGR1_C PF18111.1 KXZ46909.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 Retinitis pigmentosa G-protein regulator interacting C-terminal Dockerin_1 PF00404.18 KXZ46909.1 - 0.078 13.2 0.9 4 7.7 0.0 2.7 2 0 0 2 2 2 0 Dockerin type I domain DUF3287 PF11690.8 KXZ46909.1 - 2.4 7.9 7.6 41 3.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) RPW8 PF05659.11 KXZ46909.1 - 7.1 6.3 12.8 0.75 9.5 1.4 4.3 5 0 0 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Siah-Interact_N PF09032.11 KXZ46909.1 - 9.6 6.6 19.7 13 6.2 1.2 4.4 3 0 0 3 3 3 0 Siah interacting protein, N terminal Ank_3 PF13606.6 KXZ46910.1 - 2.7e-05 24.2 0.2 0.0011 19.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXZ46910.1 - 0.00031 21.2 0.1 0.0078 16.8 0.1 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46910.1 - 0.00041 20.9 0.2 0.57 10.8 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ46910.1 - 0.004 17.4 2.1 2 8.8 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ46910.1 - 0.014 15.8 0.2 7.5 7.2 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat bZIP_1 PF00170.21 KXZ46911.1 - 0.012 15.6 11.8 0.012 15.6 11.8 2.4 1 1 2 3 3 3 0 bZIP transcription factor V_ATPase_I PF01496.19 KXZ46911.1 - 0.066 11.1 1.3 0.071 11.0 1.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KXZ46911.1 - 0.075 13.1 7.5 0.098 12.8 7.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 KXZ46911.1 - 0.14 12.6 1.0 0.24 11.8 1.0 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) L31 PF09784.9 KXZ46911.1 - 0.15 12.5 1.8 0.21 12.0 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 CENP-H PF05837.12 KXZ46911.1 - 0.21 12.0 10.7 0.31 11.4 10.7 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3959 PF13105.6 KXZ46911.1 - 0.72 9.3 4.0 0.95 8.9 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF3498 PF12004.8 KXZ46911.1 - 4.8 6.3 15.5 6 5.9 15.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) FUSC PF04632.12 KXZ46911.1 - 9 4.7 9.7 10 4.5 9.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Casc1_N PF15927.5 KXZ46913.1 - 2.5e-37 128.5 6.1 2.5e-37 128.5 6.1 2.0 1 1 1 2 2 2 1 Cancer susceptibility candidate 1 N-terminus ERM PF00769.19 KXZ46913.1 - 0.29 10.9 20.1 0.45 10.3 20.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Stathmin PF00836.19 KXZ46913.1 - 5.5 7.0 15.0 1.8 8.5 11.6 1.9 2 0 0 2 2 2 0 Stathmin family Tcp11 PF05794.13 KXZ46916.1 - 6e-10 38.8 0.0 8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Pkinase_Tyr PF07714.17 KXZ46917.1 - 3.4e-43 147.8 0.0 8.3e-39 133.4 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ46917.1 - 3.8e-40 137.9 0.0 3.3e-37 128.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ46917.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ46917.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ank_5 PF13857.6 KXZ46918.1 - 1.8e-05 24.9 0.1 0.47 10.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ46918.1 - 0.00012 22.2 0.0 28 5.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KXZ46918.1 - 0.014 16.0 0.0 0.28 11.8 0.0 2.5 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46918.1 - 0.017 15.7 0.0 3.1 8.5 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ATX_III PF08098.11 KXZ46918.1 - 0.71 10.0 7.3 0.77 9.9 1.1 2.3 2 0 0 2 2 2 0 Anemonia sulcata toxin III family Pkinase PF00069.25 KXZ46919.1 - 1.2e-29 103.6 0.0 3.8e-27 95.3 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46919.1 - 8.4e-28 97.4 0.0 9.4e-22 77.5 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ46919.1 - 0.00074 18.4 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ46919.1 - 0.00077 19.5 0.3 0.0021 18.0 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ46919.1 - 0.042 12.8 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain ATP-synt_ab PF00006.25 KXZ46920.1 - 5.4e-104 346.5 0.0 7.4e-104 346.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KXZ46920.1 - 3.5e-44 149.5 0.0 6e-44 148.8 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KXZ46920.1 - 2.7e-06 27.8 0.1 6.3e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HEAT_2 PF13646.6 KXZ46921.1 - 0.0016 18.8 0.4 0.0016 18.8 0.4 4.3 3 1 1 4 4 4 1 HEAT repeats Tti2 PF10521.9 KXZ46921.1 - 0.027 14.0 0.0 0.07 12.7 0.0 1.7 2 0 0 2 2 2 0 Tti2 family HEAT PF02985.22 KXZ46921.1 - 0.036 14.3 0.1 0.036 14.3 0.1 6.0 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 KXZ46921.1 - 0.043 14.3 22.8 3.3 8.3 0.6 5.8 5 0 0 5 5 5 0 HEAT-like repeat Astro_capsid_p PF12226.8 KXZ46921.1 - 4.9 6.2 5.6 8.3 5.5 5.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ribosomal_S3_C PF00189.20 KXZ46922.1 - 3.5e-11 43.5 0.1 7e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain VIR_N PF15912.5 KXZ46922.1 - 2.9 7.4 5.6 4.9 6.7 5.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal AAA PF00004.29 KXZ46923.1 - 4.6e-52 175.9 0.1 2.2e-38 131.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ46923.1 - 1.5e-12 47.1 0.4 4.6e-12 45.5 0.4 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXZ46923.1 - 6.3e-10 39.5 0.9 0.00061 20.1 0.2 4.8 3 2 1 4 4 4 1 AAA domain AAA_16 PF13191.6 KXZ46923.1 - 3.5e-09 37.3 0.3 0.0055 17.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 KXZ46923.1 - 5.4e-08 33.1 0.1 1.6e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXZ46923.1 - 6.6e-08 32.6 0.1 0.00031 20.8 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXZ46923.1 - 1.5e-07 31.0 0.0 0.01 15.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_7 PF12775.7 KXZ46923.1 - 5.1e-06 26.1 1.6 0.021 14.3 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region RuvB_N PF05496.12 KXZ46923.1 - 5.5e-06 26.2 0.1 0.023 14.5 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KXZ46923.1 - 8.3e-06 25.7 0.0 0.1 12.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXZ46923.1 - 3.2e-05 23.4 0.2 0.0073 15.7 0.1 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KXZ46923.1 - 5.1e-05 23.3 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KXZ46923.1 - 5.4e-05 23.2 0.0 0.25 11.4 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXZ46923.1 - 7.9e-05 23.2 0.1 0.021 15.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ46923.1 - 8.9e-05 22.8 0.0 0.073 13.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 KXZ46923.1 - 0.00012 22.0 0.7 3 7.7 0.0 4.0 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KXZ46923.1 - 0.00015 21.5 0.1 0.61 9.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.6 KXZ46923.1 - 0.00017 21.8 0.0 0.28 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXZ46923.1 - 0.00021 21.1 0.1 0.014 15.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 KXZ46923.1 - 0.00093 18.7 0.1 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ATPase PF06745.13 KXZ46923.1 - 0.0011 18.3 1.3 0.01 15.2 0.1 2.6 2 1 1 3 3 3 1 KaiC ABC_tran PF00005.27 KXZ46923.1 - 0.0015 19.1 0.1 0.19 12.2 0.1 2.8 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 KXZ46923.1 - 0.0022 17.2 0.5 1.6 7.8 0.1 2.5 2 1 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 KXZ46923.1 - 0.0023 17.9 0.2 6.6 6.6 0.0 3.5 4 0 0 4 4 3 0 NACHT domain Vps4_C PF09336.10 KXZ46923.1 - 0.0041 17.1 0.1 0.12 12.4 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_11 PF13086.6 KXZ46923.1 - 0.0093 15.8 0.0 0.62 9.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KXZ46923.1 - 0.013 15.2 0.0 1.8 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.11 KXZ46923.1 - 0.014 15.2 0.0 0.057 13.3 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXZ46923.1 - 0.014 14.9 1.3 1.5 8.4 0.0 3.4 2 2 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXZ46923.1 - 0.029 14.6 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXZ46923.1 - 0.038 14.3 0.2 0.45 10.8 0.1 2.6 3 1 0 3 3 2 0 AAA domain ResIII PF04851.15 KXZ46923.1 - 0.041 13.9 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DAP3 PF10236.9 KXZ46923.1 - 0.057 12.6 0.2 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Parvo_NS1 PF01057.17 KXZ46923.1 - 0.063 12.4 0.0 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KXZ46923.1 - 0.064 12.5 0.1 0.95 8.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 KXZ46923.1 - 0.079 12.7 0.1 7.9 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 KXZ46923.1 - 0.08 12.3 0.1 4.6 6.6 0.1 3.4 3 1 0 3 3 3 0 Bacterial TniB protein AAA_23 PF13476.6 KXZ46923.1 - 0.11 12.9 0.1 0.71 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KXZ46923.1 - 0.12 11.3 0.0 4.1 6.2 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Ank_2 PF12796.7 KXZ46924.1 - 1.2e-08 35.4 0.0 0.0071 16.9 0.0 4.2 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ46924.1 - 6.8e-08 32.9 0.8 0.45 11.2 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ46924.1 - 0.00058 20.1 1.7 10 6.6 0.0 5.8 6 1 1 7 7 7 1 Ankyrin repeats (many copies) DJ-1_PfpI PF01965.24 KXZ46925.1 - 1.3e-16 60.8 0.0 3.8e-13 49.6 0.0 2.3 2 1 0 2 2 2 2 DJ-1/PfpI family ThiJ_like PF17124.5 KXZ46925.1 - 1.4e-08 34.7 0.0 3.7e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 ThiJ/PfpI family-like Ribosomal_S27e PF01667.17 KXZ46925.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S27 ANAPC2 PF08672.11 KXZ46927.1 - 1.2e-15 57.7 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 GRP PF07172.11 KXZ46927.1 - 0.005 17.5 5.4 0.005 17.5 5.4 2.6 2 0 0 2 2 2 1 Glycine rich protein family Metallothio_PEC PF02068.16 KXZ46928.1 - 1.1 9.7 5.4 0.16 12.3 0.7 2.1 2 0 0 2 2 2 0 Plant PEC family metallothionein Pro_isomerase PF00160.21 KXZ46929.1 - 2.7e-50 170.7 0.1 1.8e-26 93.3 0.0 2.3 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAN_4 PF14295.6 KXZ46929.1 - 2.4e-09 36.9 4.4 4.4e-09 36.1 4.4 1.4 1 0 0 1 1 1 1 PAN domain His_Phos_1 PF00300.22 KXZ46932.1 - 4.3e-55 186.4 7.2 4.9e-55 186.2 7.2 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acyltransferase PF01553.21 KXZ46933.1 - 1.5e-09 37.6 0.0 7e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase SNF2_N PF00176.23 KXZ46935.1 - 1.8e-48 165.1 0.0 3.1e-35 121.6 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KXZ46935.1 - 1.4e-08 34.5 4.6 2.4e-08 33.7 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KXZ46935.1 - 1e-07 32.3 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KXZ46935.1 - 5e-06 26.4 5.3 1e-05 25.4 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ46935.1 - 2e-05 24.4 6.1 3.4e-05 23.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ46935.1 - 3.9e-05 23.4 6.5 7.1e-05 22.6 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ46935.1 - 4.5e-05 23.7 6.2 8.3e-05 22.8 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXZ46935.1 - 0.00014 21.8 4.8 0.00025 21.0 4.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXZ46935.1 - 0.00016 21.5 4.7 0.00028 20.7 4.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FYVE PF01363.21 KXZ46935.1 - 0.039 14.1 1.6 0.082 13.1 1.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.11 KXZ46935.1 - 0.25 11.3 1.0 0.47 10.4 1.0 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 KXZ46935.1 - 0.25 11.2 7.2 0.54 10.1 7.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KXZ46935.1 - 1.2 9.3 3.6 3.1 7.9 3.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon NEMO PF11577.8 KXZ46935.1 - 7.3 6.7 15.9 0.29 11.2 6.4 2.6 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO zf-C3HC4_4 PF15227.6 KXZ46935.1 - 9.2 6.5 8.1 17 5.7 8.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 KXZ46936.1 - 8.3e-31 107.3 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46936.1 - 3.7e-12 46.1 0.0 7.7e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ46936.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ARA70 PF12489.8 KXZ46937.1 - 0.1 12.8 0.1 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 Nuclear coactivator Sulfotransfer_1 PF00685.27 KXZ46938.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ46938.1 - 0.0047 17.3 1.5 0.014 15.7 0.1 2.2 2 1 1 3 3 3 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KXZ46938.1 - 0.057 13.3 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family Amnionless PF14828.6 KXZ46939.1 - 0.03 13.2 0.2 0.061 12.1 0.1 1.4 1 1 0 1 1 1 0 Amnionless DUF5084 PF16894.5 KXZ46939.1 - 0.1 13.0 0.5 0.15 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) DUF4834 PF16118.5 KXZ46939.1 - 0.12 13.4 0.0 0.19 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM100 PF16311.5 KXZ46939.1 - 0.16 11.6 1.7 0.16 11.6 0.4 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 Dimer_Tnp_hAT PF05699.14 KXZ46940.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Pre-PUA PF17832.1 KXZ46941.1 - 2.9e-16 59.9 0.0 6.1e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Pre-PUA-like domain SUI1 PF01253.22 KXZ46941.1 - 8e-10 39.1 0.0 3.1e-08 34.0 0.1 2.8 2 1 1 3 3 3 2 Translation initiation factor SUI1 HlyIII PF03006.20 KXZ46942.1 - 3.3e-66 223.2 13.9 5.8e-66 222.4 13.9 1.4 1 1 0 1 1 1 1 Haemolysin-III related Baculo_PEP_C PF04513.12 KXZ46942.1 - 9.4e-05 22.5 0.9 0.00016 21.7 0.9 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KXZ46942.1 - 0.00093 19.1 1.1 0.0019 18.1 1.1 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DASH_Dam1 PF08653.10 KXZ46942.1 - 0.012 15.4 1.0 0.087 12.6 0.0 2.3 1 1 1 2 2 2 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 KXZ46942.1 - 0.014 15.8 0.1 2.7 8.5 0.0 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.13 KXZ46942.1 - 0.019 14.5 0.7 0.23 11.0 0.6 2.3 2 0 0 2 2 2 0 fzo-like conserved region GAS PF13851.6 KXZ46942.1 - 0.037 13.4 0.3 0.052 12.9 0.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF883 PF05957.13 KXZ46942.1 - 0.053 14.1 3.4 0.058 14.0 1.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ANAPC4 PF12896.7 KXZ46942.1 - 0.06 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 ApoLp-III PF07464.11 KXZ46942.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) EzrA PF06160.12 KXZ46942.1 - 0.069 11.3 0.0 0.092 10.9 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SF-assemblin PF06705.11 KXZ46942.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin CLZ PF16526.5 KXZ46942.1 - 0.18 12.2 2.4 3.2 8.2 2.7 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1351 PF07083.11 KXZ46942.1 - 0.19 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Tmemb_cc2 PF10267.9 KXZ46942.1 - 0.22 10.6 0.7 0.32 10.1 0.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2721 PF11026.8 KXZ46942.1 - 0.77 9.6 4.3 0.43 10.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) IQ PF00612.27 KXZ46943.1 - 7.9e-05 22.1 0.0 0.00022 20.7 0.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif APG6_N PF17675.1 KXZ46945.1 - 2.5 8.6 7.3 1.1 9.8 4.3 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region JIP_LZII PF16471.5 KXZ46946.1 - 0.0037 17.4 0.5 0.0066 16.6 0.5 1.3 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II Herpes_UL25 PF01499.16 KXZ46946.1 - 0.12 10.8 1.9 0.3 9.5 1.9 1.6 1 0 0 1 1 1 0 Herpesvirus UL25 family HALZ PF02183.18 KXZ46946.1 - 0.18 12.0 4.2 1.4 9.2 0.2 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper AA_permease_2 PF13520.6 KXZ46947.1 - 1e-13 50.9 11.2 1.2e-12 47.4 11.1 2.1 1 1 0 1 1 1 1 Amino acid permease G-patch_2 PF12656.7 KXZ46948.1 - 3.4e-23 81.5 0.5 3.4e-23 81.5 0.5 2.3 2 0 0 2 2 2 1 G-patch domain KN17_SH3 PF18131.1 KXZ46948.1 - 9.2e-10 38.5 0.0 2.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 KXZ46948.1 - 1.5e-07 31.2 0.4 0.027 14.4 0.0 4.1 4 0 0 4 4 4 2 KOW motif G-patch PF01585.23 KXZ46948.1 - 7.8e-06 25.7 0.9 2.6e-05 24.0 0.9 2.0 1 0 0 1 1 1 1 G-patch domain DUF755 PF05501.11 KXZ46948.1 - 8.1 6.7 15.9 14 5.9 15.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CBF PF03914.17 KXZ46949.1 - 2.2e-48 164.5 0.0 5.4e-48 163.2 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Cnd1 PF12717.7 KXZ46949.1 - 0.25 11.4 0.1 1.4 9.0 0.1 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Pro_dh-DNA_bdg PF14850.6 KXZ46949.1 - 0.6 10.7 3.4 2 9.0 1.3 2.5 2 0 0 2 2 2 0 DNA-binding domain of Proline dehydrogenase B9-C2 PF07162.11 KXZ46950.1 - 2.9e-43 148.0 0.0 4.6e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DivIC PF04977.15 KXZ46951.1 - 0.018 14.8 1.5 0.2 11.4 1.5 2.0 1 1 0 1 1 1 0 Septum formation initiator Ribosomal_60s PF00428.19 KXZ46951.1 - 0.089 13.4 16.4 0.12 13.0 16.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2057 PF09829.9 KXZ46951.1 - 0.28 11.3 3.2 0.33 11.1 3.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) NAD_binding_8 PF13450.6 KXZ46951.1 - 0.43 10.9 0.0 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3138 PF11336.8 KXZ46951.1 - 0.53 8.8 9.6 0.5 8.9 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pkinase PF00069.25 KXZ46952.1 - 5.9e-35 120.9 0.0 6.8e-21 74.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46952.1 - 1e-30 106.9 0.0 2.2e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ46952.1 - 0.016 15.2 0.2 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ46952.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ46953.1 - 6e-20 71.6 0.0 6e-14 51.9 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ46953.1 - 1.7e-19 70.2 0.0 2.1e-11 43.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain NOG1_N PF17835.1 KXZ46954.1 - 5.2e-53 179.3 0.0 6.9e-53 178.9 0.0 1.2 1 0 0 1 1 1 1 NOG1 N-terminal helical domain MMR_HSR1 PF01926.23 KXZ46954.1 - 4.3e-18 65.5 0.0 7.2e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 KXZ46954.1 - 1.5e-15 56.7 0.2 3.2e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.18 KXZ46954.1 - 3.8e-09 36.3 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXZ46954.1 - 0.0014 18.7 0.0 1.1 9.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KXZ46954.1 - 0.0064 15.8 0.0 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KXZ46954.1 - 0.012 15.5 0.0 0.048 13.6 0.0 1.9 1 1 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 KXZ46954.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KXZ46954.1 - 0.036 13.5 0.0 0.9 8.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 KXZ46954.1 - 0.043 14.2 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXZ46954.1 - 0.066 13.8 0.0 0.41 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain Peptidase_S8 PF00082.22 KXZ46955.1 - 2.4e-30 105.9 0.2 2.4e-30 105.9 0.2 1.5 2 0 0 2 2 2 1 Subtilase family Acetyltransf_18 PF18014.1 KXZ46956.1 - 0.28 11.0 1.6 5.5 6.8 0.1 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF563 PF04577.14 KXZ46957.1 - 0.082 13.0 0.1 0.34 11.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF563) YejG PF13989.6 KXZ46957.1 - 0.17 12.3 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 YejG-like protein GCV_T PF01571.21 KXZ46958.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain RsgI_N PF12791.7 KXZ46958.1 - 0.21 11.6 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma factor N-terminus Peptidase_S9 PF00326.21 KXZ46959.1 - 1.4e-27 96.6 0.0 2.2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ribosomal_L35Ae PF01247.18 KXZ46960.1 - 1.6e-42 143.6 0.9 1.8e-42 143.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KXZ46960.1 - 0.1 12.8 0.6 5.5 7.3 0.1 2.3 2 1 0 2 2 2 0 RimM N-terminal domain E1-E2_ATPase PF00122.20 KXZ46961.1 - 1.2e-49 168.3 2.2 1.2e-49 168.3 2.2 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXZ46961.1 - 2.6e-14 54.0 0.5 9e-14 52.3 0.5 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXZ46961.1 - 6.3e-13 48.2 0.0 1.3e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXZ46961.1 - 0.00022 21.1 0.5 0.011 15.5 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ46961.1 - 0.00083 19.4 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Sulfotransfer_2 PF03567.14 KXZ46962.1 - 4e-07 30.2 2.7 1.9e-06 28.0 2.7 2.0 1 1 0 1 1 1 1 Sulfotransferase family Sulf_transp PF04143.14 KXZ46963.1 - 1.1e-10 41.6 44.2 8.2e-07 28.9 21.8 3.3 1 1 2 3 3 3 2 Sulphur transport Fringe PF02434.16 KXZ46964.1 - 0.052 13.0 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Fringe-like TPR_21 PF09976.9 KXZ46965.1 - 0.16 11.6 2.2 8.6 6.0 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain GSHPx PF00255.19 KXZ46966.1 - 7.3e-45 151.0 0.3 1.1e-44 150.5 0.3 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXZ46966.1 - 2.6e-06 27.4 0.1 1.2e-05 25.2 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ46966.1 - 0.00016 21.4 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin AA_kinase PF00696.28 KXZ46967.1 - 4.4e-44 150.9 0.0 6.5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KXZ46967.1 - 7.6e-07 28.8 0.1 0.032 14.0 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KXZ46967.1 - 0.00038 20.2 0.8 0.44 10.4 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_5 PF13710.6 KXZ46967.1 - 0.034 14.0 1.1 0.091 12.6 0.2 2.2 2 0 0 2 2 2 0 ACT domain YbaB_DNA_bd PF02575.16 KXZ46968.1 - 6.1e-16 58.4 7.2 9e-16 57.9 7.2 1.2 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family AnmK PF03702.14 KXZ46968.1 - 0.069 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase DUF842 PF05811.13 KXZ46968.1 - 0.09 12.5 1.0 0.18 11.5 1.0 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TPR_2 PF07719.17 KXZ46970.1 - 3.6e-08 32.9 0.1 5.6e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ46970.1 - 2.4e-07 30.3 0.1 3.6e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ46970.1 - 0.0025 18.4 0.3 0.011 16.3 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ46970.1 - 0.0034 17.5 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ46970.1 - 0.017 15.6 0.1 0.024 15.2 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ46970.1 - 0.019 15.7 0.1 0.047 14.5 0.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ46970.1 - 0.034 14.3 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ46970.1 - 0.067 12.9 0.1 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 TPR repeat Paf67 PF10255.9 KXZ46970.1 - 0.31 10.0 0.0 0.31 10.0 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 SRCR PF00530.18 KXZ46973.1 - 7.8e-06 26.3 0.0 1.5e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ46973.1 - 0.0025 18.3 0.0 0.005 17.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Sulfate_transp PF00916.20 KXZ46976.1 - 3.5e-92 309.1 14.9 1.5e-91 307.0 14.9 1.9 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXZ46976.1 - 1.2e-25 89.4 0.0 2.5e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KXZ46976.1 - 0.00023 21.5 0.0 0.00065 20.0 0.0 1.8 2 0 0 2 2 2 1 STAS domain PHO4 PF01384.20 KXZ46976.1 - 0.18 10.8 5.9 0.18 10.9 1.2 2.2 2 0 0 2 2 2 0 Phosphate transporter family Pkinase PF00069.25 KXZ46977.1 - 6.7e-71 238.7 0.0 8.9e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ46977.1 - 1.8e-34 119.2 0.0 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ46977.1 - 1.1e-06 28.2 0.0 5.6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXZ46977.1 - 0.00054 19.4 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ46977.1 - 0.0072 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KXZ46977.1 - 0.11 12.1 0.1 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXZ46977.1 - 0.12 12.3 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family VbhA PF18495.1 KXZ46977.1 - 0.12 12.2 0.3 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 Antitoxin VbhA RIO1 PF01163.22 KXZ46977.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Bac_DNA_binding PF00216.21 KXZ46977.1 - 0.16 12.2 0.0 3.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial DNA-binding protein Zip PF02535.22 KXZ46978.1 - 0.063 12.5 0.6 0.073 12.3 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AMPK1_CBM PF16561.5 KXZ46979.1 - 4.5e-34 116.5 0.8 1.1e-33 115.3 0.4 1.7 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KXZ46979.1 - 1.1e-22 80.1 4.1 1.9e-22 79.3 4.1 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KXZ46979.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Guanylate_cyc_2 PF09778.9 KXZ46980.1 - 2.1e-29 102.4 0.0 2.5e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 KXZ46980.1 - 0.0017 18.9 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 KXZ46980.1 - 0.025 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 DUF3335 PF11814.8 KXZ46980.1 - 0.037 13.5 0.0 0.28 10.6 0.0 2.0 1 1 1 2 2 2 0 Peptidase_C39 like family DAHP_synth_1 PF00793.20 KXZ46980.1 - 0.14 11.0 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family WD40 PF00400.32 KXZ46981.1 - 4.7e-07 30.4 0.0 0.00033 21.4 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ46981.1 - 9.9e-07 29.0 0.5 0.00019 21.7 0.3 3.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KXZ46981.1 - 0.046 11.7 0.2 0.057 11.4 0.2 1.0 1 0 0 1 1 1 0 IKI3 family DUF4362 PF14275.6 KXZ46981.1 - 0.1 12.9 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) PAS_9 PF13426.7 KXZ46983.1 - 3.3e-12 46.6 0.0 0.032 14.5 0.0 4.6 2 2 2 4 4 4 4 PAS domain PAS PF00989.25 KXZ46983.1 - 4.8e-12 45.9 0.3 0.00071 19.6 0.0 4.3 4 1 1 5 5 5 3 PAS fold PAS_4 PF08448.10 KXZ46983.1 - 1.6e-05 25.1 0.0 0.012 15.8 0.0 4.1 4 0 0 4 4 4 1 PAS fold PAS_3 PF08447.12 KXZ46983.1 - 0.00029 21.0 0.0 0.85 10.0 0.0 4.1 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.7 KXZ46983.1 - 0.0054 16.7 0.0 19 5.4 0.0 3.7 3 0 0 3 3 3 1 PAS domain Nitroreductase PF00881.24 KXZ46984.1 - 3.8e-29 101.9 0.1 4.8e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family SPC12 PF06645.13 KXZ46984.1 - 0.33 11.1 2.3 0.76 9.9 2.3 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PhoR PF11808.8 KXZ46984.1 - 1.2 9.6 3.9 0.82 10.1 0.2 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR FAM91_C PF14648.6 KXZ46985.1 - 3.3e-53 181.1 0.0 3.2e-52 177.8 0.0 2.4 1 1 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 KXZ46985.1 - 1.9e-38 132.5 0.0 7.7e-32 110.8 0.0 2.1 1 1 1 2 2 2 2 FAM91 N-terminus WD40 PF00400.32 KXZ46986.1 - 3.2e-56 186.0 24.9 5.7e-06 27.0 0.1 13.8 13 0 0 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ46986.1 - 4.4e-34 116.6 0.0 0.0028 17.9 0.0 12.5 3 3 10 13 13 13 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ46986.1 - 7.1e-11 41.6 5.1 0.53 9.2 0.0 9.3 5 3 5 11 11 11 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXZ46986.1 - 6.6e-09 35.5 4.0 2.6 7.3 0.0 8.7 6 5 3 10 10 10 3 Neuroblastoma-amplified sequence, N terminal APG6_N PF17675.1 KXZ46986.1 - 0.0079 16.7 2.1 0.014 15.9 2.1 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Proteasome_A_N PF10584.9 KXZ46986.1 - 0.011 15.4 0.3 6.8 6.5 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature AAA_13 PF13166.6 KXZ46986.1 - 0.019 13.7 2.8 0.025 13.2 2.8 1.1 1 0 0 1 1 1 0 AAA domain Hira PF07569.11 KXZ46986.1 - 0.055 13.2 1.2 89 2.7 0.0 4.9 6 1 1 7 7 7 0 TUP1-like enhancer of split Cytochrom_D1 PF02239.16 KXZ46986.1 - 0.085 11.4 0.0 15 3.9 0.0 3.5 3 1 1 4 4 4 0 Cytochrome D1 heme domain Exonuc_VII_L PF02601.15 KXZ46986.1 - 0.095 12.3 4.8 0.16 11.6 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4763 PF15960.5 KXZ46986.1 - 0.13 11.6 2.1 0.2 11.0 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) AIP3 PF03915.13 KXZ46986.1 - 0.22 10.6 1.6 0.31 10.1 1.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF4407 PF14362.6 KXZ46986.1 - 0.22 10.8 8.4 0.4 10.0 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF148 PF02520.17 KXZ46986.1 - 0.55 10.4 6.7 0.94 9.6 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 RHS_repeat PF05593.14 KXZ46986.1 - 1.4 9.5 4.3 42 4.8 0.4 3.8 3 0 0 3 3 3 0 RHS Repeat SRP-alpha_N PF04086.13 KXZ46986.1 - 2.2 8.1 6.8 0.25 11.3 0.6 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal NUT PF12881.7 KXZ46987.1 - 0.12 10.7 4.3 0.21 10.0 4.3 1.3 1 0 0 1 1 1 0 NUT protein zf-C2H2_jaz PF12171.8 KXZ46988.1 - 4.2e-07 30.1 3.1 0.0026 18.0 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXZ46988.1 - 3.7e-06 27.3 4.3 0.035 14.9 0.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXZ46988.1 - 1.9e-05 24.8 4.5 0.019 15.4 0.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KXZ46988.1 - 0.012 15.9 3.4 0.16 12.3 0.5 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KXZ46988.1 - 0.032 14.6 1.2 2.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING_7 PF02591.15 KXZ46988.1 - 0.033 14.4 2.1 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf_C2H2_ZHX PF18387.1 KXZ46988.1 - 0.035 13.7 0.2 0.067 12.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Sgf11 PF08209.11 KXZ46988.1 - 0.072 12.7 0.2 0.072 12.7 0.2 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_2 PF12756.7 KXZ46988.1 - 0.088 13.2 3.3 4.4 7.7 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KXZ46988.1 - 0.098 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 KXZ46988.1 - 0.13 12.1 3.1 3.9 7.4 0.3 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif DEC-1_N PF04625.13 KXZ46988.1 - 0.15 11.0 4.1 0.14 11.1 4.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FOXP-CC PF16159.5 KXZ46988.1 - 0.21 12.3 1.4 13 6.5 0.2 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain YbgS PF13985.6 KXZ46988.1 - 1.1 9.6 0.1 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 YbgS-like protein Rhodanese_C PF12368.8 KXZ46989.1 - 5.9e-19 68.2 4.5 1e-18 67.5 4.5 1.4 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 KXZ46989.1 - 2.3e-15 56.7 0.0 3.9e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 KXZ46989.1 - 1.3e-10 41.8 0.0 4.2e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Atg14 PF10186.9 KXZ46989.1 - 1.3 8.0 3.5 2.5 7.1 3.5 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PI3Ka PF00613.20 KXZ46990.1 - 0.029 13.8 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KXZ46991.1 - 1.1e-34 120.5 0.1 3.2e-26 92.7 0.1 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 KXZ46991.1 - 0.0026 17.1 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) adh_short PF00106.25 KXZ46992.1 - 2.4e-08 33.7 1.4 8.4e-05 22.1 0.3 3.0 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ46992.1 - 7.8e-05 22.3 4.4 0.047 13.2 0.1 2.5 2 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase F-box PF00646.33 KXZ46993.1 - 4.5e-06 26.4 0.3 9.2e-06 25.4 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXZ46993.1 - 5.8e-06 26.2 0.1 1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KXZ46993.1 - 0.00082 19.2 0.1 0.0023 17.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like Methyltransf_21 PF05050.12 KXZ46994.1 - 5.7e-06 26.5 0.0 8.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 KXZ46994.1 - 0.00061 19.6 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MINDY_DUB PF04424.13 KXZ46995.1 - 3e-24 85.3 0.0 4.6e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase EF-hand_6 PF13405.6 KXZ46996.1 - 0.00018 21.2 0.1 0.00041 20.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KXZ46996.1 - 0.0026 17.2 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ46996.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KXZ46996.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KXZ46996.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_4 PF12763.7 KXZ46996.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Filament PF00038.21 KXZ46996.1 - 0.35 10.4 23.1 1.2 8.6 2.5 2.4 1 1 1 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.9 KXZ46996.1 - 0.58 10.5 5.4 2.1 8.7 0.6 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 KXZ46996.1 - 1.3 9.6 29.7 2.2 8.8 4.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region FAP206 PF12018.8 KXZ46996.1 - 7.4 6.0 7.1 13 5.1 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function ArfGap PF01412.18 KXZ46998.1 - 6.5e-41 139.1 0.0 9.4e-41 138.6 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf WD40 PF00400.32 KXZ46999.1 - 9.1e-11 42.1 2.9 2.7e-05 24.8 1.5 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ46999.1 - 0.0001 22.5 0.0 0.16 12.3 0.0 2.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 KXZ46999.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Nucleotid_trans PF03407.16 KXZ47000.1 - 7.7e-12 45.6 0.0 1.4e-11 44.8 0.0 1.4 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase CHRD PF07452.12 KXZ47002.1 - 7.3e-12 46.3 0.0 9.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 CHRD domain CN_hydrolase PF00795.22 KXZ47003.1 - 2.5e-28 99.1 0.0 3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HSP70 PF00012.20 KXZ47004.1 - 2e-39 135.3 0.0 1.1e-26 93.3 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein Hydrolase_4 PF12146.8 KXZ47005.1 - 2.9e-14 52.9 2.2 2e-12 46.9 0.5 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ47005.1 - 3.2e-11 43.4 0.1 2.7e-10 40.3 0.2 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ47005.1 - 1.8e-07 32.0 8.7 2.8e-07 31.4 8.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KXZ47005.1 - 6.8e-05 22.9 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KXZ47005.1 - 0.00039 20.0 0.2 0.0023 17.4 0.2 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 KXZ47005.1 - 0.0065 15.6 0.0 0.012 14.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) DUF2974 PF11187.8 KXZ47005.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 KXZ47005.1 - 0.031 13.9 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 KXZ47005.1 - 0.042 13.4 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Palm_thioest PF02089.15 KXZ47005.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.4 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 KXZ47005.1 - 0.081 12.7 0.0 21 4.8 0.0 3.3 3 1 1 4 4 4 0 Phospholipase/Carboxylesterase PaaX PF07848.12 KXZ47005.1 - 0.31 11.3 4.2 1.7 9.0 0.1 2.8 3 0 0 3 3 3 0 PaaX-like protein ubiquitin PF00240.23 KXZ47006.1 - 7.2e-07 28.9 0.0 9.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family K-box PF01486.17 KXZ47008.1 - 0.083 13.1 1.9 12 6.2 0.0 2.1 2 0 0 2 2 2 0 K-box region DivIC PF04977.15 KXZ47008.1 - 0.099 12.4 5.6 0.69 9.7 0.4 2.1 1 1 1 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 KXZ47008.1 - 0.12 12.7 5.1 0.31 11.3 5.1 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain TSC22 PF01166.18 KXZ47008.1 - 0.12 12.7 0.4 0.12 12.7 0.4 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Wbp11 PF09429.10 KXZ47008.1 - 0.97 9.9 2.9 2.3 8.7 2.9 1.6 1 1 0 1 1 1 0 WW domain binding protein 11 bZIP_2 PF07716.15 KXZ47008.1 - 7 6.8 7.5 7.5 6.7 0.9 2.2 2 0 0 2 2 2 0 Basic region leucine zipper LRR_4 PF12799.7 KXZ47009.1 - 2.8e-06 27.6 0.3 1.3 9.6 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ47009.1 - 6.6e-06 25.8 9.4 3.1 8.1 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 KXZ47009.1 - 0.0009 19.0 4.2 0.9 9.4 0.1 5.4 5 2 2 7 7 7 1 Leucine rich repeat LRR_1 PF00560.33 KXZ47009.1 - 0.035 14.6 5.5 10 7.1 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich Repeat Molybdopterin PF00384.22 KXZ47011.1 - 6.3e-70 236.3 0.0 5e-69 233.3 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KXZ47011.1 - 4.4e-19 68.3 0.4 1.2e-18 66.9 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KXZ47011.1 - 1.3e-15 57.8 0.3 4.1e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KXZ47011.1 - 2.5e-09 37.0 0.3 5.1e-09 36.0 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KXZ47011.1 - 2.9e-05 23.8 0.1 0.012 15.4 0.1 2.8 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KXZ47011.1 - 0.088 12.7 1.3 4 7.4 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain NADH-G_4Fe-4S_3 PF10588.9 KXZ47011.1 - 0.36 10.4 0.0 0.36 10.4 0.0 2.3 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4_4 PF12800.7 KXZ47011.1 - 0.49 11.0 1.6 1.4 9.6 1.6 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain Arf PF00025.21 KXZ47012.1 - 4e-41 140.4 0.1 2.2e-30 105.4 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 KXZ47012.1 - 2.9e-05 23.6 0.2 0.017 14.5 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXZ47012.1 - 0.001 18.3 0.1 0.097 11.8 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KXZ47012.1 - 0.038 14.1 0.1 0.46 10.6 0.0 2.0 1 1 1 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 KXZ47012.1 - 0.089 11.8 0.0 0.27 10.2 0.0 1.8 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KXZ47012.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_L2_C PF03947.18 KXZ47013.1 - 4.6e-47 159.3 3.2 9.7e-47 158.3 3.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXZ47013.1 - 1.2e-15 57.2 0.2 3.8e-15 55.6 0.2 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain AAA_22 PF13401.6 KXZ47014.1 - 9.2e-05 22.7 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ47014.1 - 0.0014 19.1 4.1 0.008 16.6 2.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXZ47014.1 - 0.0085 16.0 0.0 0.034 14.1 0.0 2.1 1 1 0 1 1 1 1 NACHT domain SAM_1 PF00536.30 KXZ47014.1 - 0.075 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PhoH PF02562.16 KXZ47014.1 - 0.2 11.1 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Pkinase PF00069.25 KXZ47015.1 - 1.4e-10 41.0 0.0 2.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ47015.1 - 6.5e-06 26.2 0.3 1.1e-05 25.5 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ47015.1 - 0.0043 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ47015.1 - 0.032 13.5 0.0 0.064 12.5 0.0 1.4 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ47015.1 - 0.12 11.2 0.0 0.26 10.0 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Amidase PF01425.21 KXZ47016.1 - 1e-154 515.9 0.1 1.2e-154 515.6 0.1 1.0 1 0 0 1 1 1 1 Amidase p25-alpha PF05517.12 KXZ47017.1 - 1.2e-18 67.8 0.7 7.5e-10 39.2 0.1 2.1 2 0 0 2 2 2 2 p25-alpha ABC_membrane_2 PF06472.15 KXZ47018.1 - 4.6e-43 147.6 0.4 2e-29 102.9 0.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXZ47018.1 - 2.8e-13 50.6 0.0 8.4e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 KXZ47018.1 - 6.6e-12 45.5 0.4 7.3e-05 22.4 0.1 2.1 2 0 0 2 2 2 2 SbmA/BacA-like family ABC_membrane PF00664.23 KXZ47018.1 - 7.8e-07 29.0 0.7 1e-05 25.4 0.7 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 KXZ47018.1 - 0.00045 20.6 1.7 0.00045 20.6 1.7 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KXZ47018.1 - 0.0018 18.1 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXZ47018.1 - 0.0055 16.9 1.2 0.032 14.5 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KXZ47018.1 - 0.0063 16.3 0.3 0.0063 16.3 0.3 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KXZ47018.1 - 0.0096 16.2 0.1 0.074 13.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXZ47018.1 - 0.017 15.0 0.2 0.046 13.6 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 KXZ47018.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXZ47018.1 - 0.038 13.9 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KXZ47018.1 - 0.049 14.0 0.1 0.093 13.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DLIC PF05783.11 KXZ47018.1 - 0.082 11.7 4.9 0.23 10.2 0.0 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 KXZ47018.1 - 0.27 11.7 0.0 0.56 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ47018.1 - 0.32 10.6 4.1 0.28 10.7 0.3 2.6 2 1 0 2 2 2 0 AAA domain bZIP_1 PF00170.21 KXZ47019.1 - 3.9e-11 42.9 25.7 8e-09 35.5 17.4 2.5 1 1 1 2 2 2 2 bZIP transcription factor Rootletin PF15035.6 KXZ47019.1 - 0.00036 20.6 10.7 0.0007 19.7 10.7 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 KXZ47019.1 - 0.00049 20.5 9.7 0.0012 19.3 9.7 1.6 1 0 0 1 1 1 1 Cell division protein ZapB ERM PF00769.19 KXZ47019.1 - 0.0016 18.3 13.5 0.0024 17.7 13.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family YabA PF06156.13 KXZ47019.1 - 0.0026 18.4 2.5 0.0046 17.6 2.5 1.4 1 0 0 1 1 1 1 Initiation control protein YabA NRBF2 PF08961.10 KXZ47019.1 - 0.0029 17.2 4.5 0.0069 16.0 4.5 1.6 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator bZIP_2 PF07716.15 KXZ47019.1 - 0.0031 17.5 38.9 0.0082 16.2 18.6 2.9 2 1 1 3 3 2 2 Basic region leucine zipper Uso1_p115_C PF04871.13 KXZ47019.1 - 0.0085 16.5 8.1 0.021 15.2 8.1 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF812 PF05667.11 KXZ47019.1 - 0.019 13.9 5.2 0.027 13.4 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 KXZ47019.1 - 0.023 14.8 5.5 0.034 14.3 5.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 KXZ47019.1 - 0.031 14.4 8.5 0.053 13.6 8.5 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase ADIP PF11559.8 KXZ47019.1 - 0.033 14.3 17.0 0.054 13.6 17.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4472 PF14739.6 KXZ47019.1 - 0.059 14.1 8.2 0.11 13.2 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Exonuc_VII_L PF02601.15 KXZ47019.1 - 0.065 12.8 5.6 0.095 12.3 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_Maf PF03131.17 KXZ47019.1 - 0.13 12.8 23.5 0.61 10.6 8.4 2.5 1 1 1 2 2 2 0 bZIP Maf transcription factor JIP_LZII PF16471.5 KXZ47019.1 - 0.19 11.9 6.7 0.4 10.9 6.7 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 KXZ47019.1 - 0.19 11.0 9.0 0.18 11.1 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 KXZ47019.1 - 0.26 9.8 1.6 0.35 9.4 1.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 KXZ47019.1 - 0.28 11.7 15.4 0.69 10.4 15.4 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 KXZ47019.1 - 0.32 10.5 7.8 0.51 9.9 7.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Golgin_A5 PF09787.9 KXZ47019.1 - 0.34 10.3 11.1 0.51 9.8 11.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Striatin PF08232.12 KXZ47019.1 - 0.44 11.1 13.2 0.31 11.6 11.1 1.7 1 1 1 2 2 2 0 Striatin family Jnk-SapK_ap_N PF09744.9 KXZ47019.1 - 0.65 10.2 15.6 1.3 9.3 15.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CtIP_N PF10482.9 KXZ47019.1 - 0.92 9.6 13.4 2.6 8.1 2.7 2.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain FlaC_arch PF05377.11 KXZ47019.1 - 0.93 9.9 3.1 1.3 9.4 2.4 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) LCD1 PF09798.9 KXZ47019.1 - 2 6.8 12.7 35 2.7 12.7 2.0 1 1 0 1 1 1 0 DNA damage checkpoint protein V_ATPase_I PF01496.19 KXZ47019.1 - 2.3 6.1 6.1 3 5.7 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 KXZ47019.1 - 2.3 8.0 16.4 1.8 8.4 2.7 2.8 2 1 1 3 3 3 0 Septum formation initiator Atg14 PF10186.9 KXZ47019.1 - 5.7 5.9 8.6 8.2 5.4 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KXZ47019.1 - 7.4 6.3 11.1 11 5.7 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Vma12 PF11712.8 KXZ47022.1 - 2.1e-06 27.9 0.0 4.7e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase WD40 PF00400.32 KXZ47023.1 - 1.2e-09 38.6 8.7 0.00039 21.2 0.0 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat ABC_tran PF00005.27 KXZ47023.1 - 1.8e-07 31.8 0.0 1.8e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 ABC transporter ANAPC4_WD40 PF12894.7 KXZ47023.1 - 4.5e-05 23.7 0.0 0.11 12.8 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_21 PF13304.6 KXZ47023.1 - 0.0095 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ47023.1 - 0.023 14.1 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PALB2_WD40 PF16756.5 KXZ47023.1 - 0.088 11.7 0.2 3.9 6.3 0.1 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KXZ47023.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF4407 PF14362.6 KXZ47023.1 - 0.32 10.3 4.1 0.48 9.7 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SbcCD_C PF13558.6 KXZ47023.1 - 0.34 11.2 0.0 0.34 11.2 0.0 2.0 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ADK PF00406.22 KXZ47024.1 - 9.3e-30 103.7 0.0 7.3e-29 100.8 0.0 1.9 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXZ47024.1 - 8e-24 84.6 0.0 1.1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ47024.1 - 1.5e-07 32.0 0.0 3.5e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ47024.1 - 2.8e-05 24.3 0.1 7.6e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KXZ47024.1 - 8.8e-05 22.3 0.2 0.0049 16.6 0.0 2.3 1 1 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.12 KXZ47024.1 - 0.012 14.9 0.1 0.068 12.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 KXZ47024.1 - 0.012 16.2 0.0 0.055 14.0 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 KXZ47024.1 - 0.019 14.9 0.0 0.48 10.3 0.0 2.3 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 SKI PF01202.22 KXZ47024.1 - 0.026 14.6 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase CoaE PF01121.20 KXZ47024.1 - 0.076 12.7 0.2 5.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase PAS_7 PF12860.7 KXZ47024.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold AAA_19 PF13245.6 KXZ47024.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4536 PF15055.6 KXZ47025.1 - 0.023 14.9 2.0 0.042 14.1 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) TMA7 PF09072.10 KXZ47026.1 - 6.5e-20 71.7 16.0 7.1e-20 71.6 16.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 MttA_Hcf106 PF02416.16 KXZ47027.1 - 6e-18 63.9 0.2 8e-18 63.5 0.2 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family LRR_6 PF13516.6 KXZ47028.1 - 2.2e-17 61.5 26.2 0.0006 19.7 0.0 8.3 9 0 0 9 9 9 6 Leucine Rich repeat LRR_1 PF00560.33 KXZ47028.1 - 1.7e-05 24.7 0.2 5.2 8.0 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich Repeat Pox_L5 PF04872.13 KXZ47028.1 - 0.0079 16.1 0.5 4 7.4 0.0 2.6 2 0 0 2 2 2 2 Poxvirus L5 protein family AAA_27 PF13514.6 KXZ47028.1 - 0.14 11.7 5.9 0.068 12.8 3.3 1.8 2 0 0 2 2 2 0 AAA domain FmdE PF02663.14 KXZ47028.1 - 0.2 11.7 0.8 0.36 10.9 0.8 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon SUIM_assoc PF16619.5 KXZ47028.1 - 0.31 11.1 14.1 0.69 10.0 14.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LRR_4 PF12799.7 KXZ47028.1 - 0.37 11.3 9.6 5 7.7 3.3 4.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ47028.1 - 1 9.2 16.3 4.5 7.1 3.3 4.9 5 1 0 6 6 6 0 Leucine rich repeat Spt20 PF12090.8 KXZ47028.1 - 1.3 8.5 11.1 1.9 8.1 11.1 1.2 1 0 0 1 1 1 0 Spt20 family Ank_2 PF12796.7 KXZ47029.1 - 9.5e-10 38.9 0.0 0.1 13.2 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47029.1 - 4.8e-08 33.4 4.5 1.1 10.0 0.1 6.7 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ47029.1 - 0.00012 22.3 1.2 2e+02 3.1 0.0 7.3 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 KXZ47029.1 - 0.0025 18.1 4.1 58 4.2 0.0 5.8 7 0 0 7 7 7 0 Ankyrin repeats (many copies) HTH_39 PF14090.6 KXZ47029.1 - 0.029 14.1 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain RHD3 PF05879.12 KXZ47030.1 - 2.4e-183 611.2 0.0 7.7e-181 602.9 0.0 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KXZ47030.1 - 1.4e-06 27.8 0.1 2.4e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KXZ47030.1 - 0.0002 21.4 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXZ47030.1 - 0.00082 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 KXZ47030.1 - 0.022 15.3 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KXZ47030.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KXZ47030.1 - 0.14 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXZ47030.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXZ47030.1 - 0.23 11.8 0.0 0.23 11.8 0.0 3.8 3 2 0 3 3 3 0 AAA ATPase domain ATPase_2 PF01637.18 KXZ47030.1 - 0.24 11.3 0.0 0.43 10.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Dor1 PF04124.12 KXZ47031.1 - 3.2e-93 312.1 0.0 4e-93 311.8 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 KXZ47031.1 - 2.5e-07 30.7 0.2 7.7e-07 29.1 0.2 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Exo84_C PF16528.5 KXZ47031.1 - 0.0036 17.2 0.0 0.018 14.8 0.0 2.1 1 1 0 1 1 1 1 Exocyst component 84 C-terminal Allexi_40kDa PF05549.11 KXZ47031.1 - 0.045 13.3 0.8 0.073 12.6 0.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein COG2 PF06148.11 KXZ47031.1 - 0.091 12.8 1.7 0.19 11.8 1.7 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sas6_CC PF18594.1 KXZ47031.1 - 0.14 11.9 2.0 0.15 11.8 0.6 1.8 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain RRM_1 PF00076.22 KXZ47032.1 - 2.6e-23 81.6 0.0 8.3e-13 48.0 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXZ47032.1 - 1.6e-05 24.8 0.1 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif CCDC53 PF10152.9 KXZ47032.1 - 0.034 14.6 2.7 0.047 14.1 2.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RRM_occluded PF16842.5 KXZ47032.1 - 0.072 13.0 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif BRAP2 PF07576.12 KXZ47032.1 - 0.11 12.7 0.0 3.6 7.9 0.0 2.1 2 0 0 2 2 2 0 BRCA1-associated protein 2 Ank_4 PF13637.6 KXZ47034.1 - 1.1e-12 48.2 1.4 0.00032 21.2 0.1 6.1 5 3 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47034.1 - 1e-10 42.0 0.0 9.4e-06 26.1 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47034.1 - 0.00014 22.0 0.9 1.7e+02 3.3 0.0 7.0 8 0 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ47034.1 - 0.00023 21.4 3.6 0.85 10.0 0.0 6.3 6 1 1 7 7 7 1 Ankyrin repeats (many copies) SnoaL_2 PF12680.7 KXZ47034.1 - 0.93 10.2 3.3 0.71 10.5 0.2 2.5 3 1 0 3 3 3 0 SnoaL-like domain Ank_4 PF13637.6 KXZ47035.1 - 7.5e-11 42.3 6.0 0.41 11.3 0.2 7.4 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47035.1 - 3.9e-10 40.2 0.0 0.035 14.7 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47035.1 - 0.015 15.8 5.4 3.9e+02 2.2 0.0 7.7 10 0 0 10 10 10 0 Ankyrin repeat F-box PF00646.33 KXZ47035.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 F-box domain Ank_5 PF13857.6 KXZ47035.1 - 1.7 9.0 16.6 2.7 8.4 0.0 6.6 8 1 1 9 9 9 0 Ankyrin repeats (many copies) CobT PF06213.12 KXZ47035.1 - 4.4 6.6 32.5 0.32 10.3 27.7 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Ank_4 PF13637.6 KXZ47036.1 - 0.0064 17.1 0.8 9 7.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ47037.1 - 2.1e-06 28.2 0.0 0.86 10.3 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47037.1 - 0.00027 21.5 0.0 0.031 14.9 0.0 2.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47037.1 - 0.00061 20.1 0.3 4.9 8.0 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat DNA_gyraseB PF00204.25 KXZ47038.1 - 6.4e-49 165.8 0.0 9.9e-49 165.1 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 KXZ47038.1 - 3.2e-22 78.5 0.0 5.6e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 KXZ47038.1 - 1.4e-19 70.6 0.0 2.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KXZ47038.1 - 1.3e-14 54.2 0.0 2.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 KXZ47038.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyrid_oxidase_2 PF13883.6 KXZ47039.1 - 4.8e-44 150.3 0.0 5.4e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3855 PF12967.7 KXZ47039.1 - 0.053 13.5 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) His_Phos_1 PF00300.22 KXZ47040.1 - 7e-18 65.0 0.7 5.4e-16 58.9 0.6 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SMC_N PF02463.19 KXZ47041.1 - 1.7e-19 70.2 0.0 2.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXZ47041.1 - 4.2e-19 69.8 4.5 4.2e-19 69.8 4.5 4.3 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXZ47041.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KXZ47041.1 - 0.03 14.0 0.2 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KXZ47041.1 - 0.15 11.8 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system HALZ PF02183.18 KXZ47041.1 - 0.23 11.7 8.4 2.1 8.6 0.3 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 KXZ47041.1 - 1.7 9.2 11.3 11 6.6 0.3 5.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXZ47041.1 - 3.6 8.1 5.3 11 6.5 0.1 4.4 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) zf-C3HC4_3 PF13920.6 KXZ47042.1 - 1.6e-07 31.0 10.0 3.3e-07 30.1 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 KXZ47042.1 - 0.0002 21.4 2.0 0.00063 19.9 0.1 2.2 1 1 1 2 2 2 1 K-box region zf-C3HC4_2 PF13923.6 KXZ47042.1 - 0.0032 17.3 11.6 0.0066 16.3 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KXZ47042.1 - 0.0096 15.6 6.1 0.018 14.7 6.1 1.5 1 0 0 1 1 1 1 P-11 zinc finger TerY_C PF15616.6 KXZ47042.1 - 0.025 14.7 1.3 0.043 13.9 1.3 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain Taxilin PF09728.9 KXZ47042.1 - 0.12 11.5 0.9 0.19 10.9 0.9 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein zf-C3HC4 PF00097.25 KXZ47042.1 - 0.3 11.0 9.1 0.82 9.6 9.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ47042.1 - 0.79 9.7 18.3 0.075 13.0 12.0 2.4 2 1 1 3 3 3 0 zinc-RING finger domain Snapin_Pallidin PF14712.6 KXZ47042.1 - 0.96 9.9 6.2 0.35 11.3 1.6 2.5 3 0 0 3 3 3 0 Snapin/Pallidin DUF4515 PF14988.6 KXZ47042.1 - 0.96 9.2 5.8 0.3 10.9 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) zf-RING_2 PF13639.6 KXZ47042.1 - 1.3 9.4 14.4 0.67 10.3 11.7 2.0 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 KXZ47042.1 - 3 7.8 13.2 18 5.3 13.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Adeno_E1B_55K_N PF04623.12 KXZ47042.1 - 6 7.6 11.1 0.14 12.8 2.1 2.7 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus DivIC PF04977.15 KXZ47042.1 - 8 6.3 10.4 8.7 6.2 3.0 3.1 2 1 1 3 3 3 0 Septum formation initiator SMC_N PF02463.19 KXZ47043.1 - 4.7e-20 72.0 0.1 6.3e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXZ47043.1 - 9.9e-14 52.3 0.1 9.9e-14 52.3 0.1 4.9 3 1 1 4 4 4 1 AAA domain APG6_N PF17675.1 KXZ47043.1 - 0.00023 21.7 2.1 0.00023 21.7 2.1 6.4 3 2 3 6 6 6 2 Apg6 coiled-coil region AAA_29 PF13555.6 KXZ47043.1 - 0.0022 17.7 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXZ47043.1 - 0.0024 17.8 0.5 0.089 12.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KXZ47043.1 - 0.099 13.2 7.8 0.14 12.7 0.0 3.4 2 1 0 2 2 2 0 ABC transporter AAA_15 PF13175.6 KXZ47043.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DDE_Tnp_ISL3 PF01610.17 KXZ47043.1 - 8.1 6.1 20.8 0.87 9.2 10.4 2.8 2 0 0 2 2 2 0 Transposase Calmodulin_bind PF07887.11 KXZ47044.1 - 3.2e-14 52.9 0.0 1.3e-12 47.6 0.0 2.7 1 1 0 1 1 1 1 Calmodulin binding protein-like bZIP_C PF12498.8 KXZ47044.1 - 0.097 13.7 1.1 0.47 11.4 1.1 2.3 1 0 0 1 1 1 0 Basic leucine-zipper C terminal Psb28 PF03912.14 KXZ47046.1 - 7.5e-27 93.7 0.8 4e-25 88.1 0.2 2.0 1 1 1 2 2 2 2 Psb28 protein RCC1_2 PF13540.6 KXZ47047.1 - 4.5e-31 106.0 37.5 4.3e-08 32.7 0.6 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXZ47047.1 - 3.5e-29 101.2 20.4 0.0001 22.8 0.0 10.1 9 1 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat TPR_12 PF13424.6 KXZ47047.1 - 0.0021 18.3 12.7 0.009 16.3 4.2 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ47047.1 - 0.77 10.0 8.5 18 5.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ApbA PF02558.16 KXZ47048.1 - 0.038 13.7 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TFIIIC_sub6 PF10419.9 KXZ47049.1 - 7.9e-08 32.1 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Epimerase PF01370.21 KXZ47050.1 - 1.1e-10 41.4 0.0 2.9e-06 26.9 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXZ47050.1 - 7.6e-07 29.2 0.0 2.3e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXZ47050.1 - 1e-06 28.4 0.0 0.009 15.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXZ47050.1 - 0.00065 19.3 0.0 0.0014 18.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Glyco_transf_28 PF03033.20 KXZ47050.1 - 0.048 13.7 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain HSP70 PF00012.20 KXZ47053.1 - 4.9e-73 246.3 0.0 4.9e-73 246.3 0.0 4.2 3 1 0 3 3 3 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ47053.1 - 1.8e-06 27.0 0.0 4.4e-05 22.5 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein EMP70 PF02990.16 KXZ47054.1 - 8.5e-222 737.4 8.7 1.2e-221 737.0 8.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 CopD PF05425.13 KXZ47054.1 - 0.015 15.7 3.3 0.015 15.7 3.3 3.6 4 0 0 4 4 4 0 Copper resistance protein D dCMP_cyt_deam_1 PF00383.23 KXZ47055.1 - 1e-06 28.5 1.6 2.2e-05 24.3 1.6 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXZ47055.1 - 0.00026 20.8 0.3 0.006 16.3 0.1 2.2 2 0 0 2 2 2 1 MafB19-like deaminase AAA PF00004.29 KXZ47056.1 - 1.9e-42 144.8 0.0 3.9e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXZ47056.1 - 2.9e-18 65.6 0.6 5.5e-18 64.7 0.6 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXZ47056.1 - 1.1e-11 44.3 0.2 2.8e-11 43.0 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ47056.1 - 3.5e-07 30.3 0.3 1.1e-06 28.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ47056.1 - 5.1e-06 27.0 0.7 0.0016 18.8 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXZ47056.1 - 5.6e-05 22.9 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ47056.1 - 0.00011 22.4 3.3 0.007 16.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KXZ47056.1 - 0.00011 22.3 0.0 0.00042 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KXZ47056.1 - 0.0029 17.2 0.0 0.0076 15.8 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region TMF_TATA_bd PF12325.8 KXZ47056.1 - 0.0059 16.8 1.1 0.016 15.5 1.1 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding AAA_33 PF13671.6 KXZ47056.1 - 0.013 15.7 0.1 0.058 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KXZ47056.1 - 0.014 14.9 0.1 0.079 12.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.13 KXZ47056.1 - 0.021 14.0 0.0 0.043 13.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXZ47056.1 - 0.03 14.0 0.0 0.098 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ47056.1 - 0.036 14.6 0.1 0.3 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXZ47056.1 - 0.041 13.3 0.1 0.14 11.5 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXZ47056.1 - 0.044 13.5 0.1 0.52 10.0 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KXZ47056.1 - 0.064 12.6 0.6 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KXZ47056.1 - 0.098 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KXZ47056.1 - 0.11 12.2 0.9 0.57 9.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain Atg14 PF10186.9 KXZ47056.1 - 0.17 11.0 0.6 0.25 10.4 0.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 KXZ47056.1 - 0.27 11.9 2.4 0.45 11.2 1.2 1.9 2 0 0 2 2 2 0 Initiation control protein YabA AAA_19 PF13245.6 KXZ47056.1 - 0.29 11.5 3.2 1.5 9.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain CCDC73 PF15818.5 KXZ47056.1 - 0.61 7.9 7.0 0.86 7.4 7.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family CIDE-N PF02017.15 KXZ47056.1 - 0.67 10.0 0.0 0.67 10.0 0.0 2.2 3 0 0 3 3 1 0 CIDE-N domain Cpn60_TCP1 PF00118.24 KXZ47057.1 - 1.4e-154 515.4 13.8 1.6e-154 515.2 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mito_carr PF00153.27 KXZ47058.1 - 1.6e-41 140.2 0.2 4.2e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein TLD PF07534.16 KXZ47059.1 - 9e-20 71.3 0.0 3.1e-16 59.8 0.0 2.1 1 1 1 2 2 2 2 TLD GSHPx PF00255.19 KXZ47060.1 - 5.7e-41 138.5 0.1 1e-40 137.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXZ47060.1 - 6.5e-06 26.1 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ47060.1 - 7.6e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin Presenilin PF01080.17 KXZ47060.1 - 0.23 10.2 2.1 0.29 9.8 2.1 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 KXZ47060.1 - 1.5 9.8 6.5 20 6.2 5.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 KXZ47060.1 - 3.5 7.2 22.0 6.1 6.4 22.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF2859 PF11072.8 KXZ47060.1 - 5.1 6.8 9.1 2.1 8.1 4.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2859) RNase_PH PF01138.21 KXZ47061.1 - 1.3e-22 80.7 0.2 1.9e-22 80.2 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXZ47061.1 - 3e-06 27.2 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Strep_pep PF14404.6 KXZ47061.1 - 1.2 9.5 2.9 2.6 8.4 0.1 2.7 2 1 1 3 3 3 0 Ribosomally synthesized peptide in Streptomyces species IQ PF00612.27 KXZ47062.1 - 0.00025 20.6 0.2 0.00025 20.6 0.2 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif PreAtp-grasp PF18604.1 KXZ47062.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Pre ATP-grasp domain Med26 PF08711.11 KXZ47063.1 - 1.7e-11 43.9 0.0 4.5e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 TFIIS helical bundle-like domain YL1 PF05764.13 KXZ47063.1 - 0.011 15.8 20.0 0.011 15.8 20.0 3.2 3 1 0 3 3 3 0 YL1 nuclear protein OSR1_C PF12202.8 KXZ47063.1 - 2.2 8.6 7.5 17 5.7 0.1 4.0 4 0 0 4 4 4 0 Oxidative-stress-responsive kinase 1 C-terminal domain Alfin PF12165.8 KXZ47064.1 - 5.6e-61 203.8 0.0 6.6e-61 203.6 0.0 1.0 1 0 0 1 1 1 1 Alfin SHR-BD PF06650.12 KXZ47066.1 - 1e-19 71.0 0.0 1.2e-18 67.5 0.0 2.2 1 1 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 KXZ47066.1 - 1.5e-07 31.3 0.0 5.5e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KXZ47066.1 - 0.016 15.5 0.1 0.064 13.6 0.1 2.1 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain C2 PF00168.30 KXZ47066.1 - 0.094 13.0 0.0 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 C2 domain FAST_1 PF06743.15 KXZ47069.1 - 0.001 19.0 0.1 0.28 11.2 0.0 3.1 2 1 0 2 2 2 2 FAST kinase-like protein, subdomain 1 DUF21 PF01595.20 KXZ47070.1 - 3.1e-12 46.6 0.6 4.6e-12 46.0 0.6 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain ArAE_1 PF06081.11 KXZ47070.1 - 0.048 13.8 0.5 0.079 13.1 0.5 1.3 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 NAM-associated PF14303.6 KXZ47071.1 - 9.1 7.0 10.8 3.6 8.3 3.5 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Peptidase_C65 PF10275.9 KXZ47072.1 - 5.9e-70 235.5 0.0 7e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KXZ47072.1 - 0.0058 17.1 0.0 0.078 13.5 0.0 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease Kri1_C PF12936.7 KXZ47073.1 - 4.4e-23 81.3 1.5 4.4e-23 81.3 1.5 3.3 3 0 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 KXZ47073.1 - 7.7e-20 71.4 8.2 7.7e-20 71.4 8.2 4.9 3 2 2 5 5 5 1 KRI1-like family Nop PF01798.18 KXZ47074.1 - 1.2e-85 286.7 0.1 2.5e-85 285.6 0.1 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXZ47074.1 - 1.7e-13 50.7 6.4 3.4e-12 46.6 6.4 2.7 1 1 0 1 1 1 1 NOP5NT (NUC127) domain Sugarporin_N PF11471.8 KXZ47074.1 - 0.0092 15.9 0.4 0.027 14.4 0.4 1.9 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension RNA_polI_A34 PF08208.11 KXZ47074.1 - 2.4 8.2 31.3 5.5 7.0 31.3 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AP2 PF00847.20 KXZ47075.1 - 8.1e-19 67.6 17.7 5.8e-06 26.5 1.5 4.6 4 0 0 4 4 4 4 AP2 domain TM231 PF10149.9 KXZ47076.1 - 2.8e-33 115.5 6.2 9.7e-28 97.4 4.4 2.0 1 1 1 2 2 2 2 Transmembrane protein 231 FG-GAP PF01839.23 KXZ47076.1 - 0.056 13.6 0.1 0.099 12.8 0.1 1.4 1 0 0 1 1 1 0 FG-GAP repeat La PF05383.17 KXZ47077.1 - 1.2e-20 73.4 0.1 2e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 La domain NARG2_C PF10505.9 KXZ47078.1 - 0.033 13.7 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus UCR_14kD PF02271.16 KXZ47078.1 - 0.14 12.1 0.1 1.6 8.8 0.1 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Gpi16 PF04113.14 KXZ47079.1 - 8.4e-28 97.1 0.0 2.9e-27 95.4 0.0 1.7 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component GATase_7 PF13537.6 KXZ47080.1 - 4.4e-14 52.4 0.0 8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXZ47080.1 - 1.2e-11 44.9 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXZ47080.1 - 1.5e-10 40.9 0.0 8.1e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Aluminium induced protein HARE-HTH PF05066.13 KXZ47081.1 - 1.3e-10 41.5 0.0 2.8e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain PBP1_TM PF14812.6 KXZ47081.1 - 3.7 8.0 8.3 0.1 13.0 1.3 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GSH_synthase PF03199.15 KXZ47082.1 - 0.042 14.3 0.3 0.35 11.3 0.1 2.8 2 0 0 2 2 2 0 Eukaryotic glutathione synthase S6OS1 PF15676.5 KXZ47082.1 - 0.55 8.6 8.9 1.7 7.0 8.9 1.8 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family DUF1897 PF09005.10 KXZ47083.1 - 1.3 8.6 5.2 2 7.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) TSNAXIP1_N PF15739.5 KXZ47084.1 - 6.2e-13 49.1 7.3 2.1e-12 47.4 0.2 2.1 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus Atg14 PF10186.9 KXZ47084.1 - 0.058 12.5 3.4 0.088 11.9 3.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 KXZ47084.1 - 0.25 10.8 8.9 0.26 10.7 8.5 1.2 1 1 0 1 1 1 0 Golgin subfamily A member 5 YabA PF06156.13 KXZ47084.1 - 0.69 10.6 4.4 1.7 9.4 0.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA SIMPL PF04402.14 KXZ47084.1 - 7.1 7.0 8.7 13 6.1 6.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF541) LSM PF01423.22 KXZ47085.1 - 9.1e-12 44.5 0.1 9.8e-12 44.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXZ47085.1 - 8.6e-07 29.0 0.0 9.6e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KXZ47085.1 - 0.064 13.4 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain U3_assoc_6 PF08640.11 KXZ47086.1 - 2.5e-26 91.6 5.3 6.7e-26 90.2 5.3 1.8 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 Suf PF05843.14 KXZ47086.1 - 0.0014 18.7 1.3 0.0049 16.9 0.1 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KXZ47086.1 - 0.27 12.2 0.2 0.27 12.2 0.2 7.2 7 2 1 8 8 8 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KXZ47086.1 - 0.54 9.3 5.2 0.28 10.3 1.5 2.3 3 0 0 3 3 3 0 NRDE-2, necessary for RNA interference HEAT_PBS PF03130.16 KXZ47087.1 - 0.052 14.2 2.4 0.28 12.0 0.1 3.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat 3Beta_HSD PF01073.19 KXZ47088.1 - 3.2e-39 134.6 0.0 5.3e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXZ47088.1 - 2.8e-26 92.5 0.1 5.8e-26 91.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXZ47088.1 - 1.2e-14 54.1 0.2 6.9e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXZ47088.1 - 2.3e-10 40.7 0.0 5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXZ47088.1 - 9.3e-09 34.8 0.0 2.1e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXZ47088.1 - 1.4e-05 24.7 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXZ47088.1 - 1.4e-05 24.4 0.5 4e-05 22.9 0.5 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KXZ47088.1 - 0.00013 21.9 1.3 0.0021 18.0 1.3 2.3 1 1 0 1 1 1 1 KR domain RCC1 PF00415.18 KXZ47089.1 - 2.4e-38 130.5 17.3 1.5e-09 38.3 0.0 7.2 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ47089.1 - 1.5e-19 69.3 38.8 5.5e-05 22.8 2.2 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KXZ47089.1 - 0.14 11.9 1.2 1.3e+02 2.1 0.0 4.4 6 0 0 6 6 6 0 TUP1-like enhancer of split SurA_N_3 PF13624.6 KXZ47089.1 - 0.24 11.2 3.0 0.46 10.3 3.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Pkinase PF00069.25 KXZ47092.1 - 1.6e-28 99.8 0.0 2.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47092.1 - 9.1e-27 94.0 0.0 5.7e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47093.1 - 2.8e-29 102.3 0.0 6e-29 101.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47093.1 - 3e-27 95.5 0.0 1.5e-19 70.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Guanylate_cyc PF00211.20 KXZ47095.1 - 2.8e-07 30.4 0.0 3.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SBP_bac_8 PF13416.6 KXZ47095.1 - 7.1e-06 26.0 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXZ47095.1 - 2e-05 24.7 0.0 2e-05 24.7 0.0 2.6 3 0 0 3 3 3 1 Bacterial extracellular solute-binding protein Gpi1 PF05024.15 KXZ47096.1 - 4.1e-07 30.3 0.1 1.3e-05 25.4 0.0 2.1 2 0 0 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) DUF812 PF05667.11 KXZ47098.1 - 0.082 11.8 31.1 0.0045 16.0 20.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Hamartin PF04388.12 KXZ47098.1 - 0.47 9.1 13.2 0.61 8.7 13.2 1.0 1 0 0 1 1 1 0 Hamartin protein GAS PF13851.6 KXZ47098.1 - 2.6 7.4 43.7 1.9 7.8 1.7 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KXZ47098.1 - 7.2 7.0 41.9 0.4 11.1 16.9 2.9 2 1 1 3 3 3 0 Fez1 Axin_b-cat_bind PF08833.10 KXZ47100.1 - 1.8 8.7 4.4 0.59 10.3 0.2 2.4 2 0 0 2 2 2 0 Axin beta-catenin binding domain GlcNAc_2-epim PF07221.11 KXZ47101.1 - 1.4e-10 41.0 0.0 4.3e-05 22.9 0.0 3.5 3 1 0 3 3 3 3 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DEAD_2 PF06733.15 KXZ47102.1 - 4e-35 121.0 0.0 5.8e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 KXZ47102.1 - 1.9e-34 119.3 0.0 3.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain CCM2_C PF16545.5 KXZ47102.1 - 0.0015 19.0 0.0 0.0031 18.0 0.0 1.4 1 0 0 1 1 1 1 Cerebral cavernous malformation protein, harmonin-homology zf-C3HC4_3 PF13920.6 KXZ47102.1 - 0.0076 16.1 9.1 0.014 15.3 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ47102.1 - 2.6 8.1 10.8 5.2 7.1 10.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KXZ47102.1 - 3.6 7.5 9.1 7.2 6.6 9.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 KXZ47103.1 - 1.6e-29 103.1 0.0 7e-17 61.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47103.1 - 3.3e-28 98.7 0.0 8.3e-13 48.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 KXZ47103.1 - 0.11 11.7 0.0 11 5.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KXZ47103.1 - 0.18 11.2 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ47104.1 - 3e-30 105.5 0.0 8.4e-18 64.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47104.1 - 5.8e-29 101.2 0.0 6.1e-13 48.6 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 KXZ47104.1 - 0.04 13.3 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ47104.1 - 0.24 10.7 0.0 17 4.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 KXZ47106.1 - 2e-31 109.4 0.0 2.3e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47106.1 - 3.9e-30 105.0 0.0 4.2e-13 49.2 0.0 3.3 3 1 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 KXZ47106.1 - 0.0052 16.2 0.1 0.0082 15.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ47106.1 - 0.2 10.9 0.0 2 7.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 KXZ47107.1 - 5.2e-28 98.1 0.0 1.5e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47107.1 - 6.7e-28 97.7 0.0 7.9e-21 74.5 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ47110.1 - 7.2e-30 104.1 0.0 4.1e-22 78.7 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47110.1 - 9.7e-30 103.8 0.0 3.1e-29 102.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47112.1 - 4.4e-28 98.3 0.0 1e-20 74.1 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47112.1 - 8.4e-28 97.4 0.0 1.6e-27 96.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47114.1 - 7.5e-16 58.2 0.0 1.5e-05 24.4 0.0 3.1 1 1 2 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ47114.1 - 9.1e-15 54.7 0.0 1.2e-06 28.2 0.0 3.0 2 1 1 3 3 3 3 Protein kinase domain Pkinase PF00069.25 KXZ47116.1 - 7.8e-23 81.2 0.0 1.9e-22 79.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47116.1 - 6e-22 78.2 0.0 3.5e-21 75.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ47116.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ47118.1 - 3.4e-22 79.1 0.0 8.5e-22 77.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47118.1 - 1.2e-17 64.0 0.0 1.6e-09 37.5 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ47118.1 - 0.068 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ47120.1 - 7.4e-33 113.9 0.0 8.9e-16 57.9 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ47120.1 - 5.8e-32 111.1 0.0 7.7e-18 64.8 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ47120.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ47122.1 - 1.5e-35 122.9 0.0 2.2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47122.1 - 5.1e-33 114.5 0.0 6e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ47122.1 - 0.00086 19.3 1.7 0.43 10.5 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ47122.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ47122.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1563 PF07599.11 KXZ47122.1 - 0.52 10.5 1.1 3.3 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) Pkinase PF00069.25 KXZ47123.1 - 2.2e-34 119.0 0.0 3.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47123.1 - 2.8e-33 115.3 0.0 2e-26 92.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ47123.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ47124.1 - 2.9e-30 105.5 0.0 4.2e-17 62.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47124.1 - 1.4e-28 99.9 0.0 1.2e-12 47.7 0.0 3.4 3 1 0 3 3 3 3 Protein tyrosine kinase HARE-HTH PF05066.13 KXZ47125.1 - 0.21 12.0 0.0 0.3 11.5 0.0 1.2 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Pkinase PF00069.25 KXZ47126.1 - 3.1e-21 75.9 0.0 4.5e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47126.1 - 6.2e-15 55.2 0.0 3.8e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ47126.1 - 0.049 12.4 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXZ47126.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ47126.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ47127.1 - 3.1e-10 39.8 0.0 4.8e-10 39.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ47127.1 - 4.4e-07 29.5 0.0 6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KXZ47128.1 - 4.7e-33 114.7 0.0 6.8e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47128.1 - 2.7e-32 112.1 0.0 7.8e-26 90.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ47128.1 - 0.25 10.7 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HARE-HTH PF05066.13 KXZ47129.1 - 0.0072 16.7 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 2 HB1, ASXL, restriction endonuclease HTH domain Nif11 PF07862.11 KXZ47129.1 - 0.13 12.6 2.0 0.58 10.5 2.0 2.2 1 0 0 1 1 1 0 Nif11 domain SOAR PF16533.5 KXZ47129.1 - 1.6 8.7 3.7 3.9 7.5 3.7 1.5 1 0 0 1 1 1 0 STIM1 Orai1-activating region Baculo_PEP_C PF04513.12 KXZ47129.1 - 2 8.5 5.0 0.74 9.9 1.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L1 PF00687.21 KXZ47131.1 - 5e-49 166.8 0.0 7.2e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DMRL_synthase PF00885.19 KXZ47132.1 - 1.1e-49 168.0 0.7 1.6e-49 167.3 0.7 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase CLZ PF16526.5 KXZ47134.1 - 0.0044 17.4 26.2 0.011 16.1 4.0 5.0 4 1 0 5 5 5 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SnoaL PF07366.12 KXZ47134.1 - 0.089 12.6 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Ax_dynein_light PF10211.9 KXZ47134.1 - 0.29 11.0 0.1 0.29 11.0 0.1 4.6 2 1 3 5 5 5 0 Axonemal dynein light chain NPV_P10 PF05531.12 KXZ47134.1 - 0.34 11.4 9.6 0.96 10.0 0.6 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 KXZ47134.1 - 0.84 9.6 18.9 0.77 9.7 0.2 4.6 5 1 0 5 5 5 0 Prefoldin subunit Tropomyosin_1 PF12718.7 KXZ47134.1 - 0.99 9.6 40.8 0.068 13.3 3.2 5.0 2 1 2 4 4 4 0 Tropomyosin like XhlA PF10779.9 KXZ47134.1 - 1.2 9.4 11.2 0.53 10.5 0.2 4.4 4 0 0 4 4 4 0 Haemolysin XhlA An_peroxidase PF03098.15 KXZ47136.1 - 1.5e-48 165.7 0.0 5.6e-44 150.6 0.0 2.1 1 1 1 2 2 2 2 Animal haem peroxidase Cytochrom_B561 PF03188.16 KXZ47136.1 - 4.1e-11 43.2 1.7 6.4e-11 42.5 1.7 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2157 PF09925.9 KXZ47136.1 - 4.5 7.1 10.5 0.73 9.6 1.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) An_peroxidase PF03098.15 KXZ47137.1 - 0.00032 19.4 0.0 0.00033 19.4 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase PP2 PF14299.6 KXZ47138.1 - 3.2e-05 24.0 0.0 3.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Phloem protein 2 An_peroxidase PF03098.15 KXZ47140.1 - 9.6e-117 390.7 0.0 4.4e-115 385.3 0.0 2.0 1 1 0 1 1 1 1 Animal haem peroxidase Cytochrom_B561 PF03188.16 KXZ47140.1 - 1.7e-10 41.2 2.0 2.8e-10 40.5 2.0 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KXZ47141.1 - 2.3e-13 50.4 0.0 4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXZ47141.1 - 2.4e-13 50.4 1.2 3.2e-13 50.0 0.8 1.4 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KXZ47141.1 - 0.32 10.8 7.2 1.8 8.4 0.2 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF2427) Ank_4 PF13637.6 KXZ47142.1 - 1.9e-06 28.3 0.0 4.1e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ47142.1 - 0.0016 18.7 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47142.1 - 0.0025 18.4 0.0 0.0034 17.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ47142.1 - 0.0036 17.7 0.0 1.8 9.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXZ47142.1 - 0.0043 17.5 0.0 3.4 8.5 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXZ47144.1 - 1e-07 32.1 0.1 1.4e-05 25.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47144.1 - 4.4e-07 30.4 0.0 4.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ47144.1 - 1.6e-05 25.1 0.0 0.00012 22.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXZ47144.1 - 0.00015 21.9 0.0 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXZ47144.1 - 0.0076 16.8 0.0 0.011 16.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47146.1 - 1.2e-10 41.8 0.3 0.00013 22.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47146.1 - 3.9e-05 23.7 1.2 28 5.7 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KXZ47146.1 - 0.00069 19.9 0.4 4 7.9 0.1 4.3 3 1 3 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ47146.1 - 0.001 19.6 0.3 8.1 7.1 0.0 3.4 2 1 2 4 4 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ47146.1 - 0.021 15.3 2.1 8.2 7.1 0.1 4.0 4 0 0 4 4 4 0 Ankyrin repeat STAR_dimer PF16544.5 KXZ47146.1 - 0.072 12.7 0.3 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein RNA_capsid PF03035.14 KXZ47147.1 - 0.0076 16.3 0.7 0.0076 16.3 0.7 1.6 2 0 0 2 2 2 1 Calicivirus putative RNA polymerase/capsid protein BAG PF02179.16 KXZ47147.1 - 0.17 12.3 0.6 0.5 10.8 0.1 2.0 2 0 0 2 2 2 0 BAG domain Ank_2 PF12796.7 KXZ47148.1 - 3.4e-10 40.4 0.9 0.00052 20.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47148.1 - 0.00021 21.5 0.1 8.6 7.3 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KXZ47148.1 - 0.02 15.5 0.1 5.8 7.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) K_channel_TID PF07941.11 KXZ47148.1 - 0.31 11.5 6.6 0.73 10.3 6.6 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain ABC_tran PF00005.27 KXZ47149.1 - 2.6e-08 34.5 0.0 3.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ47149.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DnaJ PF00226.31 KXZ47151.1 - 7.7e-20 70.8 0.9 1.1e-19 70.2 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain Apt1 PF10351.9 KXZ47154.1 - 0.039 12.8 5.9 0.045 12.6 5.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 KXZ47154.1 - 0.3 11.1 17.2 0.46 10.5 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) THUMP PF02926.17 KXZ47156.1 - 0.19 11.8 0.0 0.59 10.2 0.0 1.6 2 0 0 2 2 2 0 THUMP domain zf-MYND PF01753.18 KXZ47157.1 - 7.4e-05 22.8 9.3 0.00019 21.4 9.3 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ47158.1 - 0.00017 21.6 9.3 0.00017 21.6 9.3 2.2 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KXZ47159.1 - 5.3e-05 23.2 9.9 0.00013 22.0 9.9 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ47160.1 - 3.8e-05 23.7 9.2 0.0001 22.3 9.2 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ47161.1 - 6.5e-05 22.9 9.3 0.00015 21.8 9.3 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ47162.1 - 5.7e-05 23.1 9.9 0.00016 21.7 9.9 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ47163.1 - 0.00022 21.2 10.2 0.00022 21.2 10.2 1.9 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KXZ47164.1 - 0.00027 21.0 9.3 0.00027 21.0 9.3 2.5 2 0 0 2 2 2 1 MYND finger LysM PF01476.20 KXZ47165.1 - 7.6e-14 51.5 0.0 6e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 LysM domain DUF1381 PF07129.11 KXZ47165.1 - 0.081 12.8 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) Ribosomal_60s PF00428.19 KXZ47166.1 - 8.8 7.0 25.6 5.6 7.6 7.5 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein SRCR PF00530.18 KXZ47167.1 - 1.9e-15 57.2 0.0 3.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain ShK PF01549.24 KXZ47167.1 - 2.6e-05 24.6 1.8 0.00011 22.7 1.8 2.1 1 1 0 1 1 1 1 ShK domain-like SRCR_2 PF15494.6 KXZ47167.1 - 0.0096 16.4 0.2 0.024 15.2 0.2 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Chlam_PMP PF02415.17 KXZ47168.1 - 0.00015 22.0 45.0 0.35 11.4 0.4 6.8 7 1 0 7 7 7 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat KAR9 PF08580.10 KXZ47169.1 - 0.0089 14.6 10.1 0.014 13.9 10.1 1.3 1 1 0 1 1 1 1 Yeast cortical protein KAR9 EcsB PF05975.12 KXZ47169.1 - 0.013 14.4 0.1 0.023 13.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB TRP PF06011.12 KXZ47170.1 - 0.00024 20.0 1.9 0.00024 20.0 1.9 1.6 1 1 1 2 2 2 1 Transient receptor potential (TRP) ion channel LrgB PF04172.16 KXZ47170.1 - 0.03 13.9 2.2 0.039 13.5 2.2 1.1 1 0 0 1 1 1 0 LrgB-like family TRP PF06011.12 KXZ47171.1 - 0.00025 19.9 3.1 0.00035 19.4 3.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP PF06011.12 KXZ47174.1 - 2.3e-07 29.9 7.4 2.3e-07 29.9 7.4 2.5 3 1 0 3 3 3 1 Transient receptor potential (TRP) ion channel TAF6_C PF07571.13 KXZ47174.1 - 0.017 15.4 0.4 9.1 6.7 0.0 2.9 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain DUF3176 PF11374.8 KXZ47174.1 - 2.6 8.3 6.0 22 5.3 0.0 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3176) CBP_BcsF PF11120.8 KXZ47174.1 - 4.7 7.4 7.5 24 5.1 0.2 3.2 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF SRCR PF00530.18 KXZ47175.1 - 1.4e-17 64.0 0.7 2.2e-17 63.4 0.7 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ47175.1 - 0.0091 16.5 0.2 0.019 15.5 0.2 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain PAP2 PF01569.21 KXZ47176.1 - 0.0061 16.3 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KXZ47177.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 PAP2 superfamily TRP PF06011.12 KXZ47178.1 - 1.8e-05 23.7 8.6 2.6e-05 23.2 8.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel MFS_1 PF07690.16 KXZ47179.1 - 8e-34 117.1 51.3 1.6e-29 103.0 32.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3446 PF11928.8 KXZ47179.1 - 4.8 7.5 8.9 0.45 10.9 0.7 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain Thioredoxin PF00085.20 KXZ47180.1 - 1.8e-19 69.6 0.0 2.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXZ47180.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXZ47180.1 - 0.018 15.5 0.1 0.15 12.5 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KXZ47180.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Tad PF13400.6 KXZ47180.1 - 0.048 14.0 0.9 0.048 14.0 0.9 2.2 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF2721 PF11026.8 KXZ47180.1 - 0.11 12.3 0.7 0.21 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DOMON PF03351.17 KXZ47181.1 - 1.8e-15 57.2 0.0 2.9e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXZ47181.1 - 1.4e-05 25.2 1.4 0.0012 18.9 0.5 2.3 2 0 0 2 2 2 2 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 KXZ47181.1 - 0.067 12.8 1.3 0.59 9.7 1.9 2.1 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4079 PF13301.6 KXZ47181.1 - 0.38 10.9 3.1 1.8 8.7 3.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Sulfotransfer_2 PF03567.14 KXZ47182.1 - 0.00052 20.0 0.3 0.0009 19.2 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family Serine_protease PF18405.1 KXZ47182.1 - 0.094 11.9 0.0 3.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Gammaproteobacterial serine protease BTB PF00651.31 KXZ47183.1 - 1.2e-19 70.6 0.0 2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Prefoldin PF02996.17 KXZ47184.1 - 4e-09 36.4 0.0 7.4e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 KXZ47184.1 - 0.0031 17.7 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding HrpB7 PF09486.10 KXZ47184.1 - 0.057 13.8 5.1 2.4 8.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) MscS_porin PF12795.7 KXZ47184.1 - 1.9 8.0 5.1 1.3 8.5 0.7 2.3 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain CPBP PF02517.16 KXZ47186.1 - 1.1e-18 67.3 9.8 2.3e-18 66.4 9.8 1.9 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease BacteriocIIc_cy PF12173.8 KXZ47186.1 - 0.015 15.5 0.1 0.08 13.2 0.0 2.0 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like Ank_4 PF13637.6 KXZ47187.1 - 2.6e-18 66.1 7.8 0.0025 18.3 0.2 7.4 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47187.1 - 3.4e-14 53.2 5.7 0.004 17.7 0.0 5.1 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47187.1 - 4.3e-10 39.0 4.4 43 5.2 0.0 9.5 9 1 1 10 10 10 0 Ankyrin repeat Glycos_transf_N PF04413.16 KXZ47187.1 - 0.003 17.2 0.1 0.0069 16.0 0.1 1.6 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Ank_5 PF13857.6 KXZ47187.1 - 0.02 15.2 12.8 32 5.0 0.1 7.1 5 2 3 8 8 8 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ47187.1 - 0.82 10.2 3.8 1.1e+02 3.5 0.3 4.8 4 2 0 4 4 4 0 Ankyrin repeat BTB PF00651.31 KXZ47188.1 - 6.2e-19 68.3 0.0 9.4e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Tuberculin PF12198.8 KXZ47188.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Theoretical tuberculin protein BTB PF00651.31 KXZ47189.1 - 9.9e-19 67.6 0.0 1.6e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ47190.1 - 4.9e-20 71.8 0.0 7.8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Tuberculin PF12198.8 KXZ47190.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Theoretical tuberculin protein Ank_2 PF12796.7 KXZ47191.1 - 1e-08 35.7 0.0 0.0005 20.6 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47191.1 - 1.2e-06 28.9 0.0 5.2 7.8 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ47191.1 - 1e-05 25.5 0.0 8.5 7.3 0.0 5.3 5 1 1 6 6 6 1 Ankyrin repeat Linocin_M18 PF04454.12 KXZ47193.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Encapsulating protein for peroxidase Stm1_N PF09598.10 KXZ47193.1 - 4.7 8.1 11.8 1.1 10.1 7.3 2.2 2 1 0 2 2 2 0 Stm1 zf-MYND PF01753.18 KXZ47194.1 - 2.7e-07 30.6 8.9 6.8e-07 29.3 8.9 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ47195.1 - 9.6e-08 32.0 9.1 2.7e-07 30.6 9.1 1.8 1 0 0 1 1 1 1 MYND finger Pkinase_Tyr PF07714.17 KXZ47197.1 - 1e-11 44.7 0.0 9.3e-10 38.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47197.1 - 2.9e-11 43.2 0.0 6e-08 32.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Ribosomal_L17 PF01196.19 KXZ47199.1 - 5.2e-30 104.2 0.1 7e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Pkinase PF00069.25 KXZ47201.1 - 3.9e-35 121.5 0.0 1.1e-32 113.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47201.1 - 1.7e-33 116.0 0.0 1.1e-31 110.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ47201.1 - 0.0027 17.7 0.1 0.0027 17.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ47201.1 - 0.056 12.2 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ47202.1 - 8.2e-44 149.9 0.0 1.7e-40 139.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47202.1 - 6.1e-40 137.1 0.0 2.6e-36 125.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ47202.1 - 0.006 16.5 0.2 0.006 16.5 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ47202.1 - 0.034 12.9 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ47203.1 - 5.7e-32 111.1 0.0 7.2e-27 94.4 0.0 3.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47203.1 - 6.1e-32 110.9 0.0 4.8e-27 94.9 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ47203.1 - 0.0056 16.6 0.0 0.0056 16.6 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ47203.1 - 0.23 10.2 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2158 PF09926.9 KXZ47204.1 - 0.056 13.2 0.1 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized small protein (DUF2158) ATG101 PF07855.12 KXZ47205.1 - 2.3e-39 134.8 0.1 8.2e-39 133.1 0.1 1.7 1 1 0 1 1 1 1 Autophagy-related protein 101 GvpL_GvpF PF06386.11 KXZ47205.1 - 0.0024 17.8 0.7 0.0036 17.3 0.7 1.3 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF CCDC53 PF10152.9 KXZ47205.1 - 0.015 15.7 1.5 0.022 15.2 1.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3391 PF11871.8 KXZ47205.1 - 0.76 10.3 4.8 1.2 9.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) zf-RING_UBOX PF13445.6 KXZ47206.1 - 1e-07 31.9 7.1 2.3e-07 30.7 7.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXZ47206.1 - 4.2e-07 29.7 5.8 4.2e-07 29.7 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXZ47206.1 - 6.2e-06 26.3 9.5 1.2e-05 25.4 9.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KXZ47206.1 - 6.7e-06 26.3 7.5 6.7e-06 26.3 7.5 1.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KXZ47206.1 - 3.1e-05 23.9 4.4 7.5e-05 22.6 4.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXZ47206.1 - 3.3e-05 23.6 7.5 7.1e-05 22.6 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ47206.1 - 0.00013 21.7 7.4 0.00028 20.7 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ47206.1 - 0.0019 18.0 6.5 0.0042 16.9 6.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 BRCT PF00533.26 KXZ47206.1 - 0.0078 16.6 0.0 0.16 12.4 0.0 2.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXZ47206.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 twin BRCT domain BRCT_2 PF16589.5 KXZ47206.1 - 0.048 14.1 0.0 6.3 7.3 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain zf-Nse PF11789.8 KXZ47206.1 - 0.51 10.2 3.4 0.86 9.5 3.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KXZ47206.1 - 0.86 9.5 3.3 1.6 8.6 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KXZ47206.1 - 0.89 9.4 3.8 1.5 8.6 3.8 1.4 1 0 0 1 1 1 0 RING-like zinc finger TFIIA PF03153.13 KXZ47206.1 - 3.8 7.4 13.5 12 5.8 13.5 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APH PF01636.23 KXZ47209.1 - 0.0014 18.6 0.0 0.0059 16.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 KXZ47211.1 - 5e-10 39.8 1.4 0.0012 19.3 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47211.1 - 1.8e-06 28.4 6.4 0.084 13.5 0.0 5.9 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ47211.1 - 0.0023 18.3 4.1 33 5.5 0.2 6.1 5 2 2 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KXZ47211.1 - 0.0064 16.8 2.9 47 4.5 0.0 4.9 4 1 1 5 5 5 0 Ankyrin repeats (many copies) APH PF01636.23 KXZ47215.1 - 2.9e-28 99.4 0.0 5.5e-28 98.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXZ47215.1 - 1.3e-08 34.7 0.1 2.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH_6_hur PF04655.14 KXZ47215.1 - 0.012 15.1 0.0 0.048 13.0 0.0 1.9 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase NUDIX PF00293.28 KXZ47219.1 - 7.2e-16 58.4 0.0 1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXZ47219.1 - 1.7e-13 50.5 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L13 PF00572.18 KXZ47220.1 - 4.5e-46 156.2 0.1 6.2e-46 155.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Cyt-b5 PF00173.28 KXZ47221.1 - 0.00017 21.7 0.1 0.00021 21.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 KXZ47222.1 - 1.2e-41 142.9 0.0 1.7e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47222.1 - 4.1e-41 141.0 0.0 5e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ47222.1 - 0.0037 17.2 0.3 0.007 16.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ47222.1 - 0.0038 16.1 0.0 0.0054 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ShK PF01549.24 KXZ47224.1 - 1e-05 26.0 3.2 2.7e-05 24.6 3.2 1.8 1 0 0 1 1 1 1 ShK domain-like 2OG-FeII_Oxy_3 PF13640.6 KXZ47224.1 - 0.012 16.5 0.0 0.06 14.2 0.0 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Anti-TRAP PF15777.5 KXZ47224.1 - 0.89 9.6 0.0 0.89 9.6 0.0 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Gon7 PF08738.10 KXZ47225.1 - 0.001 19.1 0.7 0.001 19.1 0.7 2.4 1 1 1 2 2 2 1 Gon7 family Apolipoprotein PF01442.18 KXZ47225.1 - 0.031 14.1 5.1 0.025 14.4 3.4 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain MLD PF11647.8 KXZ47225.1 - 0.14 12.5 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Membrane Localization Domain DUF948 PF06103.11 KXZ47225.1 - 0.18 12.1 0.2 0.46 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) 2OG-FeII_Oxy_3 PF13640.6 KXZ47226.1 - 3.7e-19 69.4 0.0 5.7e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ47226.1 - 2.2e-07 31.3 0.0 5.5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 KXZ47226.1 - 0.0025 17.7 0.0 0.0073 16.1 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_L35p PF01632.19 KXZ47227.1 - 2.7e-18 66.2 2.8 3.7e-18 65.8 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 Serglycin PF04360.12 KXZ47229.1 - 0.066 13.2 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Serglycin Pribosyltran PF00156.27 KXZ47230.1 - 5.5e-05 22.7 0.0 9.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-MYND PF01753.18 KXZ47231.1 - 1e-06 28.7 10.0 1e-06 28.7 10.0 1.7 2 0 0 2 2 2 1 MYND finger GRP PF07172.11 KXZ47231.1 - 0.011 16.4 0.7 0.011 16.4 0.7 2.4 2 0 0 2 2 2 0 Glycine rich protein family WW PF00397.26 KXZ47232.1 - 0.00062 19.8 7.5 0.0025 17.9 1.4 2.9 3 0 0 3 3 3 2 WW domain Ribosomal_60s PF00428.19 KXZ47232.1 - 0.018 15.6 1.0 0.018 15.6 1.0 11.6 9 4 0 9 9 9 0 60s Acidic ribosomal protein SOGA PF11365.8 KXZ47232.1 - 1 10.5 3.4 2.4 9.3 3.4 1.6 1 0 0 1 1 1 0 Protein SOGA Ecm29 PF13001.7 KXZ47234.1 - 1.4e-87 294.5 0.0 1.2e-78 265.1 0.0 2.9 1 1 1 2 2 2 2 Proteasome stabiliser HEAT_EZ PF13513.6 KXZ47234.1 - 0.017 15.6 0.3 0.017 15.6 0.3 10.1 10 2 1 11 11 11 0 HEAT-like repeat HEAT_2 PF13646.6 KXZ47234.1 - 0.053 13.9 28.5 3.6 8.1 0.5 8.4 7 1 1 8 8 8 0 HEAT repeats HEAT PF02985.22 KXZ47234.1 - 1.3 9.5 24.3 5.1 7.6 0.0 8.3 9 0 0 9 9 9 0 HEAT repeat PCSK9_C3 PF18463.1 KXZ47236.1 - 0.017 15.3 0.1 0.69 10.2 0.1 2.4 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain IPP-2 PF04979.14 KXZ47238.1 - 8.1e-12 46.0 9.6 4.2e-09 37.2 9.5 2.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Sporozoite_P67 PF05642.11 KXZ47238.1 - 0.59 8.2 10.6 1.2 7.2 10.6 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.32 KXZ47241.1 - 4.4e-11 43.1 2.0 5e-05 24.0 0.4 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ47241.1 - 6.7e-07 29.5 0.0 0.51 10.7 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ47241.1 - 0.0009 19.2 0.0 0.0043 16.9 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KXZ47242.1 - 2.3e-05 25.0 0.0 2.7e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ47242.1 - 0.067 13.5 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.7 KXZ47243.1 - 4.5e-08 33.6 0.6 0.31 11.6 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47243.1 - 0.005 17.4 7.0 40 4.9 0.2 6.6 6 1 1 7 7 7 1 Ankyrin repeats (many copies) COPIIcoated_ERV PF07970.12 KXZ47245.1 - 9.1e-86 287.3 0.1 1.3e-85 286.7 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXZ47245.1 - 7.4e-18 64.7 0.1 7.4e-18 64.7 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PAN_1 PF00024.26 KXZ47248.1 - 0.017 15.1 4.0 0.14 12.2 0.5 2.2 2 0 0 2 2 2 0 PAN domain Zn_clus PF00172.18 KXZ47248.1 - 5.3 7.3 9.7 3.9 7.7 2.3 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SpoU_methylase PF00588.19 KXZ47249.1 - 1.2e-26 93.6 0.0 1.6e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family T2SSF PF00482.23 KXZ47249.1 - 0.051 13.5 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Ribosomal_L3 PF00297.22 KXZ47250.1 - 2.4e-182 606.0 8.0 2.7e-182 605.8 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 N6-adenineMlase PF10237.9 KXZ47251.1 - 3.9e-28 98.3 0.0 1.2e-23 83.6 0.0 2.0 1 1 1 2 2 2 2 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KXZ47251.1 - 0.028 14.1 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 BRE1 PF08647.11 KXZ47252.1 - 0.012 15.7 3.9 0.012 15.7 3.9 4.6 4 1 1 5 5 4 0 BRE1 E3 ubiquitin ligase CCDC-167 PF15188.6 KXZ47252.1 - 0.013 15.8 1.0 0.013 15.8 1.0 3.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 FlaC_arch PF05377.11 KXZ47252.1 - 0.015 15.7 3.2 5.2 7.5 0.0 4.9 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) Fungal_TACC PF12709.7 KXZ47252.1 - 0.025 15.0 7.5 0.041 14.3 0.6 3.0 3 0 0 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMF_TATA_bd PF12325.8 KXZ47252.1 - 0.54 10.5 40.1 0.077 13.2 5.8 4.5 5 0 0 5 5 5 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KXZ47252.1 - 0.7 10.3 38.5 0.45 10.9 8.8 3.4 2 1 1 3 3 3 0 Fez1 DUF4201 PF13870.6 KXZ47252.1 - 0.7 9.6 31.5 0.44 10.3 4.4 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) SKA2 PF16740.5 KXZ47252.1 - 0.94 9.3 28.4 0.86 9.4 4.3 5.1 4 1 0 5 5 5 0 Spindle and kinetochore-associated protein 2 FapA PF03961.13 KXZ47252.1 - 1.6 7.3 14.7 1.8 7.1 1.9 3.1 3 0 0 3 3 3 0 Flagellar Assembly Protein A YabA PF06156.13 KXZ47252.1 - 1.7 9.3 23.2 0.036 14.7 3.0 4.3 4 1 0 4 4 4 0 Initiation control protein YabA KASH_CCD PF14662.6 KXZ47252.1 - 1.8 8.3 35.3 0.19 11.6 4.6 3.6 4 0 0 4 4 4 0 Coiled-coil region of CCDC155 or KASH VPS38 PF17649.1 KXZ47252.1 - 2.4 7.0 3.4 0.8 8.5 0.3 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting 38 PKcGMP_CC PF16808.5 KXZ47252.1 - 3.8 7.4 10.7 5.7 6.9 0.0 3.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 KXZ47252.1 - 6.2 6.1 39.9 0.12 11.7 7.5 3.9 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding CENP-B_dimeris PF09026.10 KXZ47253.1 - 0.42 11.0 10.7 1.2 9.6 10.6 1.8 1 1 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 KXZ47253.1 - 6.5 6.9 11.1 14 5.9 11.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 LRRFIP PF09738.9 KXZ47254.1 - 0.025 14.1 1.8 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 LRRFIP family CENP-F_leu_zip PF10473.9 KXZ47254.1 - 0.071 13.1 7.9 0.27 11.2 2.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KXZ47254.1 - 0.21 12.3 0.2 11 6.7 0.0 2.4 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KXZ47254.1 - 4.2 7.9 11.6 9.6 6.7 5.7 2.4 2 0 0 2 2 2 0 Cell division protein ZapB zf-C4H2 PF10146.9 KXZ47254.1 - 5.7 7.2 7.4 0.36 11.1 0.1 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein AA_kinase PF00696.28 KXZ47256.1 - 3.4e-40 138.1 0.7 4.3e-40 137.8 0.7 1.1 1 0 0 1 1 1 1 Amino acid kinase family Pkinase PF00069.25 KXZ47257.1 - 3.2e-29 102.1 0.0 2e-26 92.9 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47257.1 - 2.2e-24 86.2 0.0 2.6e-19 69.5 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ47257.1 - 0.024 13.4 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXZ47257.1 - 0.3 11.0 7.6 0.12 12.3 3.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1771 PF08590.10 KXZ47258.1 - 1.6e-13 50.8 14.4 1.6e-13 50.8 14.4 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KXZ47258.1 - 1.3e-10 41.5 0.4 8.9e-10 38.8 0.1 2.6 2 0 0 2 2 2 1 Smr domain PAM2 PF07145.15 KXZ47258.1 - 2.7e-07 29.8 0.2 0.0022 17.5 0.0 2.8 2 0 0 2 2 2 2 Ataxin-2 C-terminal region Tropomyosin_1 PF12718.7 KXZ47259.1 - 0.0042 17.2 13.2 0.0042 17.2 13.2 13.1 6 4 5 13 13 13 4 Tropomyosin like ATG16 PF08614.11 KXZ47259.1 - 0.0049 17.1 18.2 0.0049 17.1 18.2 12.5 3 3 7 12 12 12 7 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KXZ47259.1 - 0.0062 16.6 3.5 0.0062 16.6 3.5 14.0 6 5 8 15 15 15 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ORF11CD3 PF10549.9 KXZ47259.1 - 2.4 8.4 5.6 1.6 8.9 0.3 3.6 3 0 0 3 3 3 0 ORF11CD3 domain YabA PF06156.13 KXZ47259.1 - 2.9 8.6 75.3 1.9 9.2 0.8 13.7 8 4 4 13 13 13 0 Initiation control protein YabA Proteasome PF00227.26 KXZ47262.1 - 7.1e-50 169.1 0.1 9.1e-50 168.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXZ47262.1 - 6.8e-14 51.2 0.1 1.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature YadA_anchor PF03895.15 KXZ47262.1 - 0.11 12.7 1.1 0.3 11.2 1.1 1.7 1 0 0 1 1 1 0 YadA-like membrane anchor domain Ribosomal_60s PF00428.19 KXZ47263.1 - 0.95 10.1 6.7 0.66 10.6 4.8 1.7 1 1 1 2 2 2 0 60s Acidic ribosomal protein JTB PF05439.12 KXZ47264.1 - 0.00014 21.9 2.5 0.012 15.7 1.4 2.3 2 1 0 2 2 2 2 Jumping translocation breakpoint protein (JTB) CENP-T_C PF15511.6 KXZ47266.1 - 2.6e-07 30.7 0.1 3.2e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KXZ47266.1 - 0.0066 16.6 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KXZ47266.1 - 0.0081 16.5 0.1 0.011 16.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXZ47266.1 - 0.051 13.6 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KXZ47266.1 - 0.064 13.6 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BDV_G PF06208.11 KXZ47266.1 - 0.066 12.4 0.0 0.077 12.1 0.0 1.0 1 0 0 1 1 1 0 Borna disease virus G protein Histone PF00125.24 KXZ47266.1 - 0.15 12.5 0.2 0.18 12.2 0.2 1.3 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Glyco_hydro_63 PF03200.16 KXZ47267.1 - 1.6e-72 244.9 0.0 1.4e-27 96.7 0.1 4.0 2 2 1 3 3 3 3 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KXZ47267.1 - 3.9e-36 125.3 0.0 6.1e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain FtsQ PF03799.15 KXZ47268.1 - 0.041 14.7 1.0 0.15 12.9 0.8 2.0 1 1 1 2 2 2 0 Cell division protein FtsQ Pkinase_Tyr PF07714.17 KXZ47269.1 - 7e-52 176.3 0.0 7.1e-39 133.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47269.1 - 1.1e-46 159.3 0.0 4.2e-46 157.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain PB1 PF00564.24 KXZ47269.1 - 0.00019 21.3 0.1 0.00072 19.4 0.0 2.0 2 0 0 2 2 2 1 PB1 domain APH PF01636.23 KXZ47269.1 - 0.0017 18.3 5.4 0.0044 17.0 0.0 3.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXZ47269.1 - 0.24 10.4 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BOP1NT PF08145.12 KXZ47270.1 - 4e-28 99.1 7.6 5.1e-28 98.7 7.6 1.1 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KXZ47270.1 - 1e-18 67.3 7.3 2.6e-05 24.9 0.0 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ47270.1 - 1.6e-05 25.1 0.0 0.19 12.1 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Adeno_E3_CR1 PF02440.15 KXZ47270.1 - 0.17 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 BOP1NT PF08145.12 KXZ47271.1 - 1.2e-07 31.9 0.4 1.9e-07 31.3 0.4 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain YjbE PF11106.8 KXZ47271.1 - 0.2 11.9 5.1 0.45 10.8 5.1 1.6 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE SMP_LBD PF17047.5 KXZ47272.1 - 0.016 14.7 0.0 2.6 7.5 0.0 2.4 3 0 0 3 3 3 0 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KXZ47272.1 - 0.043 14.1 0.0 3.5 8.0 0.0 2.9 3 1 0 3 3 3 0 C2 domain Patatin PF01734.22 KXZ47273.1 - 5.3e-09 36.6 2.1 6.3e-07 29.8 2.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Ank_2 PF12796.7 KXZ47275.1 - 9.9e-23 80.5 2.7 3.4e-11 43.6 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ47275.1 - 1.7e-19 69.3 8.6 0.0015 18.9 0.2 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ47275.1 - 4.8e-18 65.3 3.4 4.5e-10 39.9 0.1 3.9 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ47275.1 - 3.4e-16 57.7 1.9 0.016 15.7 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXZ47275.1 - 7.9e-14 51.6 7.4 0.0093 16.3 0.1 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) SET PF00856.28 KXZ47276.1 - 0.0082 16.5 0.0 0.026 14.9 0.0 1.8 1 1 0 1 1 1 1 SET domain Kinesin PF00225.23 KXZ47277.1 - 5.4e-94 314.8 0.0 9e-94 314.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ47277.1 - 1.4e-20 73.8 0.0 2.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Mlf1IP PF10248.9 KXZ47279.1 - 3.6e-17 62.9 0.3 5.4e-17 62.3 0.3 1.2 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein IQ PF00612.27 KXZ47281.1 - 3.6e-13 48.0 39.0 0.00061 19.4 3.4 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif Macoilin PF09726.9 KXZ47281.1 - 1.3 7.5 16.3 3.6 6.0 16.5 1.5 1 1 0 1 1 1 0 Macoilin family Pkinase PF00069.25 KXZ47282.1 - 4.3e-46 157.4 0.0 1.9e-29 102.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain EF-hand_1 PF00036.32 KXZ47282.1 - 2e-22 77.0 0.1 2.4e-06 26.7 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ47282.1 - 6.1e-22 77.9 0.0 1.2e-11 44.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.17 KXZ47282.1 - 3.3e-20 72.5 0.0 6.3e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_6 PF13405.6 KXZ47282.1 - 2.2e-18 64.5 0.9 4.8e-06 26.1 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXZ47282.1 - 3.8e-18 65.1 0.0 1.7e-07 31.0 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KXZ47282.1 - 3.8e-18 64.1 0.6 0.00088 18.7 0.0 4.5 4 0 0 4 4 4 4 EF hand DnaJ_C PF01556.18 KXZ47283.1 - 1.8e-44 151.4 0.1 2.4e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXZ47283.1 - 1.8e-14 53.6 0.9 3.1e-14 52.8 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain RAP PF08373.10 KXZ47284.1 - 0.048 13.8 0.0 0.059 13.5 0.0 1.1 1 0 0 1 1 1 0 RAP domain RNA_pol_A_bac PF01000.26 KXZ47286.1 - 3e-23 82.3 0.0 1.5e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXZ47286.1 - 2.4e-17 62.1 0.0 3.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PDZ_3 PF17815.1 KXZ47287.1 - 3e-45 153.6 0.0 5.1e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KXZ47287.1 - 6e-21 75.9 1.0 1.3e-20 74.8 1.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXZ47287.1 - 4.7e-18 65.8 0.0 7.3e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KXZ47287.1 - 2e-05 24.8 0.0 0.0018 18.6 0.0 2.8 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 KXZ47287.1 - 0.004 15.9 0.1 0.0063 15.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase S46 PDZ PF00595.24 KXZ47287.1 - 0.0058 17.0 0.2 0.24 11.8 0.0 3.0 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 KXZ47287.1 - 0.023 14.6 0.3 14 5.6 0.0 3.1 2 0 0 2 2 2 0 PDZ domain TPR_16 PF13432.6 KXZ47288.1 - 4.4e-09 36.8 1.2 0.0053 17.4 0.6 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ47288.1 - 1.2e-08 35.1 1.3 0.019 15.8 0.2 4.9 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ47288.1 - 2.1e-08 33.6 2.8 0.0076 16.3 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ47288.1 - 1.4e-07 31.9 4.5 0.0019 18.7 0.2 3.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ47288.1 - 0.00011 22.4 1.6 0.015 15.6 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ47288.1 - 0.00037 20.5 1.8 8.7 6.8 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ47288.1 - 0.00043 20.1 1.1 37 4.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ47288.1 - 0.014 14.7 0.3 0.023 13.9 0.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ47288.1 - 0.017 15.5 2.9 15 6.2 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ47288.1 - 0.019 15.6 5.3 8.6 7.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ47288.1 - 0.023 14.8 1.7 0.058 13.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KXZ47288.1 - 0.072 13.0 0.4 0.49 10.3 0.0 2.3 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Alkyl_sulf_dimr PF14863.6 KXZ47288.1 - 0.1 13.0 0.1 0.56 10.7 0.0 2.1 1 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_1 PF00515.28 KXZ47288.1 - 0.29 11.0 6.5 5.9 6.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 KXZ47290.1 - 4.2e-37 127.5 0.0 1.7e-36 125.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ47290.1 - 1.4e-08 34.4 0.1 3.1e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ47290.1 - 2.8e-07 30.6 0.2 2.7e-06 27.4 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ47290.1 - 7.7e-06 26.4 5.0 0.00074 19.9 0.0 3.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXZ47290.1 - 1.3e-05 25.5 0.5 0.00091 19.5 0.1 3.0 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KXZ47290.1 - 1.5e-05 24.8 0.0 5.4e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXZ47290.1 - 0.00011 21.8 0.1 0.00062 19.3 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXZ47290.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KXZ47290.1 - 0.00024 21.6 0.0 0.00051 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ47290.1 - 0.00025 21.2 0.0 0.00097 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXZ47290.1 - 0.0011 18.4 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KXZ47290.1 - 0.0011 18.2 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KXZ47290.1 - 0.0013 18.0 0.2 0.0041 16.4 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 KXZ47290.1 - 0.0016 18.2 0.3 0.0054 16.5 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXZ47290.1 - 0.0032 17.5 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 KXZ47290.1 - 0.0036 16.5 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KXZ47290.1 - 0.005 17.1 0.3 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KXZ47290.1 - 0.0061 16.7 0.0 0.023 14.8 0.0 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 KXZ47290.1 - 0.0064 16.6 0.1 0.018 15.1 0.0 1.8 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_25 PF13481.6 KXZ47290.1 - 0.0066 16.0 0.1 0.047 13.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ47290.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 KXZ47290.1 - 0.013 14.9 0.0 1 8.7 0.0 2.7 2 1 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 KXZ47290.1 - 0.018 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXZ47290.1 - 0.033 14.1 0.6 0.096 12.6 0.2 1.9 2 0 0 2 2 1 0 NACHT domain Sigma54_activat PF00158.26 KXZ47290.1 - 0.036 13.8 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Hydin_ADK PF17213.3 KXZ47290.1 - 0.049 13.9 0.9 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_3 PF07726.11 KXZ47290.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KXZ47290.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Guanylate_kin PF00625.21 KXZ47290.1 - 0.087 12.5 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase PhoH PF02562.16 KXZ47290.1 - 0.094 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KXZ47290.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Crp PF00325.20 KXZ47290.1 - 0.13 11.9 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family MFS_5 PF05631.14 KXZ47291.1 - 6.8e-123 410.0 5.4 8.5e-123 409.7 5.4 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KXZ47291.1 - 1e-14 54.3 32.1 1e-14 54.3 32.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ47291.1 - 0.16 10.8 20.8 0.01 14.7 2.3 3.4 3 1 1 4 4 4 0 Sugar (and other) transporter INCENP_ARK-bind PF03941.15 KXZ47292.1 - 5.1e-12 45.5 0.1 1.1e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ABC_tran PF00005.27 KXZ47294.1 - 3.5e-17 63.2 0.2 1.3e-08 35.4 0.0 2.4 1 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXZ47294.1 - 3.3e-10 40.3 0.1 0.0007 19.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXZ47294.1 - 0.0022 17.6 0.2 0.0052 16.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXZ47294.1 - 0.0034 17.1 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXZ47294.1 - 0.0048 16.4 0.2 2.9 7.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 KXZ47294.1 - 0.018 15.0 0.3 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KXZ47294.1 - 0.028 14.2 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KXZ47294.1 - 0.034 14.6 0.1 0.056 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXZ47294.1 - 0.036 13.7 0.1 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KXZ47294.1 - 0.05 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KXZ47294.1 - 0.059 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.6 KXZ47294.1 - 0.06 13.6 0.4 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXZ47294.1 - 0.077 12.7 0.3 0.23 11.2 0.2 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KXZ47294.1 - 0.08 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KXZ47294.1 - 0.081 13.3 0.0 0.18 12.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ47294.1 - 0.12 12.7 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KXZ47294.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DLIC PF05783.11 KXZ47294.1 - 0.25 10.1 0.0 0.4 9.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Glycos_transf_1 PF00534.20 KXZ47296.1 - 1.7e-12 47.2 0.0 9.9e-12 44.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ47296.1 - 6.2e-11 42.9 0.0 6.1e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXZ47296.1 - 0.00016 22.0 0.0 0.00046 20.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ47296.1 - 0.00036 20.6 1.4 0.0012 18.8 0.4 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glycogen_syn PF05693.13 KXZ47296.1 - 0.0032 16.1 0.0 0.0044 15.6 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase ATE_C PF04377.15 KXZ47297.1 - 5e-51 172.8 0.0 7.1e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KXZ47297.1 - 6.2e-21 74.6 0.1 1.2e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus SET PF00856.28 KXZ47298.1 - 7.4e-18 65.5 0.0 1.8e-17 64.2 0.0 1.7 1 1 0 1 1 1 1 SET domain DUF1681 PF07933.14 KXZ47299.1 - 3e-18 65.9 0.1 3e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) BTB PF00651.31 KXZ47300.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PTPA PF03095.15 KXZ47301.1 - 1.1e-122 409.3 0.0 1.3e-122 409.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF5560 PF17715.1 KXZ47301.1 - 0.084 12.3 1.2 0.14 11.5 1.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Pkinase_Tyr PF07714.17 KXZ47302.1 - 1.1e-43 149.3 0.0 1.1e-40 139.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47302.1 - 2.5e-43 148.4 0.0 7.7e-41 140.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ47302.1 - 0.00044 19.2 0.0 0.00061 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ47302.1 - 0.00092 19.2 0.9 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Bromo_coat PF01318.18 KXZ47302.1 - 0.047 13.8 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromovirus coat protein DUF2630 PF10944.8 KXZ47302.1 - 0.14 12.7 0.2 0.35 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Peptidase_M20 PF01546.28 KXZ47303.1 - 1.3e-17 64.2 5.1 1.9e-15 57.1 0.4 3.6 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXZ47303.1 - 5.1e-05 23.1 0.0 0.00015 21.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXZ47303.1 - 6.6e-05 22.7 1.0 0.00035 20.3 1.0 2.0 1 1 0 1 1 1 1 Peptidase family M28 DeoC PF01791.9 KXZ47303.1 - 0.03 13.9 0.7 0.057 13.0 0.3 1.6 2 0 0 2 2 2 0 DeoC/LacD family aldolase zf-RING_2 PF13639.6 KXZ47305.1 - 2.8e-13 50.0 4.1 4.1e-13 49.4 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ47305.1 - 1.1e-09 37.9 5.3 1.7e-09 37.3 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ47305.1 - 2e-08 34.4 7.2 7.7e-08 32.5 7.2 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXZ47305.1 - 8.6e-08 31.9 3.7 1.3e-07 31.4 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXZ47305.1 - 2.2e-07 30.5 1.2 4.1e-07 29.6 1.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KXZ47305.1 - 1.6e-06 27.9 0.9 3e-06 27.1 0.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXZ47305.1 - 3.4e-06 27.0 0.5 5.6e-06 26.3 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXZ47305.1 - 8e-06 25.6 3.7 2e-05 24.4 3.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXZ47305.1 - 2.5e-05 24.1 2.4 4.2e-05 23.3 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ47305.1 - 0.00031 20.7 4.9 0.00054 19.9 4.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KXZ47305.1 - 0.0024 17.6 2.6 0.0041 16.9 2.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 KXZ47305.1 - 0.0033 17.2 1.7 0.1 12.5 0.2 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING-like PF08746.11 KXZ47305.1 - 0.013 15.8 2.1 0.022 15.1 2.1 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 KXZ47305.1 - 0.024 14.6 4.8 0.27 11.2 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KXZ47305.1 - 0.038 13.9 3.3 0.064 13.2 3.3 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KXZ47305.1 - 0.048 13.3 4.1 0.11 12.2 4.1 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KXZ47305.1 - 0.22 11.6 7.4 0.078 13.0 2.1 2.2 2 0 0 2 2 2 0 Zinc-finger Nup192 PF11894.8 KXZ47305.1 - 0.24 8.5 0.0 0.31 8.1 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 zf-P11 PF03854.14 KXZ47305.1 - 0.36 10.5 4.6 0.15 11.7 1.8 1.7 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.7 KXZ47305.1 - 0.87 9.8 3.7 1.6 8.9 3.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-piccolo PF05715.13 KXZ47305.1 - 1.1 9.4 4.1 2.7 8.2 0.1 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger FANCL_C PF11793.8 KXZ47305.1 - 1.8 8.8 4.6 8.9 6.6 4.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KXZ47305.1 - 4.1 7.7 5.9 7.7 6.8 5.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribosomal_L22 PF00237.19 KXZ47306.1 - 3.3e-24 85.1 0.1 4.4e-24 84.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1173 PF06666.11 KXZ47306.1 - 0.064 12.2 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) RIO1 PF01163.22 KXZ47307.1 - 9.7e-73 243.8 0.0 9.7e-73 243.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KXZ47307.1 - 0.0056 16.1 0.0 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ47307.1 - 0.027 13.2 0.0 0.042 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase YL1 PF05764.13 KXZ47307.1 - 6.8 6.7 17.5 3.6 7.6 1.1 2.3 2 0 0 2 2 2 0 YL1 nuclear protein zf-RING_5 PF14634.6 KXZ47308.1 - 7e-08 32.3 3.4 7e-08 32.3 3.4 3.5 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXZ47308.1 - 1.3e-06 28.1 3.1 1.3e-06 28.1 3.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ47308.1 - 2.1e-06 27.9 4.5 2.1e-06 27.9 4.5 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ47308.1 - 0.00087 19.1 9.0 0.0032 17.3 4.1 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ47308.1 - 0.0012 18.6 5.3 0.0012 18.6 5.3 3.3 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KXZ47308.1 - 0.0096 16.0 3.6 0.0096 16.0 3.6 2.9 3 0 0 3 3 3 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KXZ47308.1 - 0.017 15.1 11.8 0.017 15.1 1.0 3.7 3 0 0 3 3 3 0 RING-type zinc-finger zf-P11 PF03854.14 KXZ47308.1 - 0.017 14.7 2.5 0.017 14.7 2.5 2.8 2 1 0 2 2 2 0 P-11 zinc finger Acetyltransf_1 PF00583.25 KXZ47309.1 - 2.1e-11 44.1 0.0 2.8e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ47309.1 - 2.7e-08 33.8 0.0 4.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ47309.1 - 7.6e-08 32.7 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ47309.1 - 3.1e-07 30.3 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXZ47309.1 - 0.0034 17.5 0.1 0.0052 16.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXZ47309.1 - 0.06 12.8 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KXZ47309.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PanZ PF12568.8 KXZ47309.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ NLPC_P60 PF00877.19 KXZ47310.1 - 0.0016 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Fimbrial_PilY2 PF14481.6 KXZ47310.1 - 0.055 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 DUF5102 PF17104.5 KXZ47311.1 - 0.052 13.6 7.2 4.2 7.3 1.6 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5102) RPN7 PF10602.9 KXZ47312.1 - 1.9e-49 167.7 1.6 2.9e-49 167.1 1.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXZ47312.1 - 2.6e-12 47.2 0.0 4.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 PCI domain Thg1 PF04446.12 KXZ47313.1 - 4.3e-51 172.2 0.0 5.8e-51 171.7 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KXZ47313.1 - 4.9e-39 133.2 0.0 9.9e-39 132.3 0.0 1.5 1 1 0 1 1 1 1 Thg1 C terminal domain Mt_ATP_synt PF15704.5 KXZ47314.1 - 4.2e-08 33.3 3.6 3.3e-07 30.4 1.6 2.7 1 1 1 2 2 2 1 Mitochondrial ATP synthase subunit SbsC_C PF18058.1 KXZ47314.1 - 3.4 7.9 8.6 0.9 9.8 4.4 2.1 2 0 0 2 2 2 0 SbsC C-terminal domain Ribosomal_L12 PF00542.19 KXZ47316.1 - 3.7e-16 59.2 9.8 1.8e-15 57.0 6.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KXZ47316.1 - 1e-15 57.1 10.0 1e-15 57.1 10.0 2.2 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Glyco_hydro_32C PF08244.12 KXZ47317.1 - 0.00075 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal XG_FTase PF03254.13 KXZ47319.1 - 6.9e-05 21.7 0.0 0.00027 19.7 0.0 1.8 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase Herpes_UL87 PF03043.14 KXZ47319.1 - 0.25 9.8 0.0 0.37 9.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family CAP_N PF01213.19 KXZ47319.1 - 4.3 6.7 3.8 6.4 6.2 3.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal BTB PF00651.31 KXZ47320.1 - 6.1e-17 61.9 0.0 9.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain ThiF PF00899.21 KXZ47321.1 - 3.5e-30 105.2 0.0 6e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF4342 PF14242.6 KXZ47321.1 - 0.93 9.5 0.1 0.93 9.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) Wtap PF17098.5 KXZ47322.1 - 0.01 15.8 0.3 0.015 15.2 0.3 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family ABC_tran_CTD PF16326.5 KXZ47322.1 - 0.011 16.0 1.6 0.025 14.8 1.4 1.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain Spc7 PF08317.11 KXZ47322.1 - 0.1 11.5 0.5 0.13 11.1 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CLZ PF16526.5 KXZ47322.1 - 0.12 12.8 1.5 0.29 11.5 1.5 1.7 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3138 PF11336.8 KXZ47322.1 - 1.1 7.9 4.4 1.4 7.5 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) zf-MYND PF01753.18 KXZ47323.1 - 0.00025 21.1 0.6 0.00064 19.8 0.6 1.7 1 0 0 1 1 1 1 MYND finger TetR_C_11 PF16859.5 KXZ47324.1 - 3.9 7.8 12.9 3.5 8.0 0.1 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain BSP_II PF05432.11 KXZ47326.1 - 0.056 13.1 7.6 0.1 12.3 7.6 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.12 KXZ47326.1 - 0.39 9.6 7.5 0.56 9.1 7.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein NOA36 PF06524.12 KXZ47326.1 - 0.53 9.5 4.4 1.3 8.3 4.4 1.5 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KXZ47326.1 - 1.1 9.0 6.2 2 8.1 6.2 1.4 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 KXZ47326.1 - 2.5 6.1 8.3 3.5 5.6 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi PspA_IM30 PF04012.12 KXZ47327.1 - 3.8e-28 98.6 26.2 2.4e-15 56.7 13.8 3.4 2 1 1 3 3 3 2 PspA/IM30 family Peptidase_M1_N PF17900.1 KXZ47327.1 - 1.9e-05 24.9 0.4 0.00054 20.2 0.0 2.6 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain YgbB PF02542.16 KXZ47327.1 - 0.098 12.9 0.4 0.2 11.9 0.4 1.4 1 0 0 1 1 1 0 YgbB family BLOC1_2 PF10046.9 KXZ47327.1 - 0.46 10.8 14.3 0.04 14.2 7.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4284 PF14112.6 KXZ47327.1 - 7.9 7.4 5.4 4.3 8.3 0.4 2.2 2 0 0 2 2 2 0 Immunity protein 22 Glyco_trans_1_4 PF13692.6 KXZ47328.1 - 7.3e-10 39.4 0.0 1.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KXZ47328.1 - 1.2e-06 28.2 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXZ47328.1 - 0.0019 18.5 0.0 0.0084 16.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_N PF04413.16 KXZ47329.1 - 1e-11 44.8 0.4 1.1e-10 41.4 0.0 2.3 2 0 0 2 2 2 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) FYRC PF05965.14 KXZ47330.1 - 0.18 12.0 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 F/Y rich C-terminus PaO PF08417.12 KXZ47331.1 - 2.9e-07 30.5 0.0 5.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Pheophorbide a oxygenase Phage_holin_3_6 PF07332.11 KXZ47331.1 - 0.028 14.5 11.8 0.079 13.0 11.8 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4231 PF14015.6 KXZ47331.1 - 0.44 11.1 3.2 0.84 10.1 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Rieske PF00355.26 KXZ47332.1 - 4e-18 65.1 0.1 9.2e-18 64.0 0.0 1.6 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ47332.1 - 6.1e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase ATP-grasp_4 PF13535.6 KXZ47333.1 - 6e-22 77.9 0.0 1.8e-20 73.1 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 KXZ47333.1 - 4e-21 75.4 0.0 1.1e-20 73.9 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_3 PF02655.14 KXZ47333.1 - 8.1e-08 32.5 0.0 4e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KXZ47333.1 - 8.4e-07 28.8 0.0 7.6e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 KXZ47333.1 - 1.2e-06 28.2 0.0 0.0005 19.7 0.0 2.4 1 1 1 2 2 2 2 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KXZ47333.1 - 8.4e-06 25.4 0.0 0.00025 20.6 0.1 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 KXZ47333.1 - 5.4e-05 23.0 0.1 0.076 12.8 0.0 3.2 1 1 1 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 KXZ47333.1 - 6.6e-05 22.6 0.0 0.0058 16.2 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.11 KXZ47333.1 - 0.0092 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain LAL_C2 PF18603.1 KXZ47333.1 - 0.01 16.0 0.0 0.031 14.4 0.0 1.9 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 ATPgrasp_ST PF14397.6 KXZ47333.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_5 PF13549.6 KXZ47333.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Pkinase PF00069.25 KXZ47334.1 - 1.4e-66 224.6 0.0 1.8e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47334.1 - 6.7e-30 104.2 0.0 1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ47334.1 - 2.9e-05 23.6 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KXZ47334.1 - 0.0045 16.7 0.2 0.0096 15.6 0.1 1.5 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXZ47334.1 - 0.029 13.7 0.8 0.054 12.8 0.8 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ47334.1 - 0.11 12.1 1.6 0.22 11.1 1.6 1.4 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXZ47334.1 - 0.12 11.2 0.1 0.22 10.2 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ocnus PF05005.15 KXZ47337.1 - 8.4e-23 80.6 0.0 1.3e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) NUDIX-like PF09296.11 KXZ47337.1 - 5.8e-11 43.0 1.2 5.8e-11 43.0 1.2 2.0 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 KXZ47337.1 - 7.2e-10 39.0 0.1 1.4e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 KXZ47337.1 - 0.05 13.3 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Pkinase PF00069.25 KXZ47338.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Rax2 PF12768.7 KXZ47340.1 - 0.086 12.3 0.2 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF202 PF02656.15 KXZ47343.1 - 3.2e-11 43.5 4.1 5.1e-11 42.9 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4203 PF13886.6 KXZ47343.1 - 0.012 15.3 1.8 0.021 14.5 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) Ycf4 PF02392.16 KXZ47343.1 - 0.12 12.0 0.2 0.2 11.2 0.2 1.6 1 1 0 1 1 1 0 Ycf4 RSN1_TM PF13967.6 KXZ47346.1 - 3.3e-25 88.7 1.4 4.7e-25 88.2 1.4 1.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Tropomyosin_1 PF12718.7 KXZ47347.1 - 0.0062 16.7 31.2 0.0062 16.7 31.2 9.1 2 2 6 9 9 9 1 Tropomyosin like APG6_N PF17675.1 KXZ47347.1 - 0.013 16.0 28.8 0.013 16.0 28.8 9.8 2 2 5 7 7 7 0 Apg6 coiled-coil region SLAC1 PF03595.17 KXZ47349.1 - 4.5e-36 124.8 39.4 4.5e-36 124.8 39.4 2.8 2 1 1 3 3 3 1 Voltage-dependent anion channel DUF4395 PF14340.6 KXZ47349.1 - 9e-25 87.5 8.8 9e-25 87.5 8.8 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF4395) Glutaredoxin PF00462.24 KXZ47349.1 - 7.1e-10 39.0 0.2 1.5e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 Glutaredoxin Hemerythrin PF01814.23 KXZ47349.1 - 3.5e-07 30.9 4.5 7.4e-07 29.8 4.5 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GST_N_3 PF13417.6 KXZ47349.1 - 0.016 15.6 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Pkinase PF00069.25 KXZ47350.1 - 9.3e-32 110.4 0.0 4e-29 101.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47350.1 - 1.7e-22 79.9 0.0 9e-20 71.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KXZ47350.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RAP PF08373.10 KXZ47351.1 - 8.5e-10 38.6 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 KXZ47351.1 - 1.5e-08 34.5 0.0 1.4 8.9 0.0 6.8 6 2 3 9 9 9 3 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 KXZ47351.1 - 0.0049 17.0 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 DUF2967 PF11179.8 KXZ47355.1 - 0.33 9.0 1.0 0.37 8.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RSN1_7TM PF02714.15 KXZ47357.1 - 4.4e-07 29.5 0.0 2.8e-06 26.9 0.0 2.0 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate GST_N PF02798.20 KXZ47358.1 - 6.2e-19 68.1 0.0 1.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXZ47358.1 - 5.9e-10 39.4 0.0 9.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXZ47358.1 - 7.5e-09 35.8 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ47358.1 - 1.3e-06 28.6 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ47358.1 - 7.7e-06 25.8 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXZ47358.1 - 6.8e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXZ47358.1 - 0.039 13.8 0.3 0.084 12.7 0.1 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Meckelin PF09773.9 KXZ47359.1 - 2.6e-156 522.1 0.3 3.1e-156 521.8 0.3 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) DUF2781 PF10914.8 KXZ47359.1 - 0.016 15.6 1.9 0.016 15.6 1.9 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF2781) Ephrin_rec_like PF07699.13 KXZ47359.1 - 0.22 11.3 3.9 7.5 6.4 0.5 2.6 2 0 0 2 2 2 0 Putative ephrin-receptor like FAM176 PF14851.6 KXZ47359.1 - 0.23 11.1 0.5 0.45 10.2 0.5 1.4 1 0 0 1 1 1 0 FAM176 family CtsR PF05848.11 KXZ47361.1 - 0.075 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 CtsR N-terminal HTH domain CENP-Q PF13094.6 KXZ47361.1 - 0.085 13.1 1.7 0.13 12.5 1.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Armet PF10208.9 KXZ47362.1 - 3.7e-06 26.9 0.0 0.00018 21.5 0.0 2.1 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding Redoxin PF08534.10 KXZ47362.1 - 2.3e-05 24.1 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXZ47362.1 - 3e-05 24.0 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXZ47362.1 - 0.0014 19.0 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like SAP PF02037.27 KXZ47362.1 - 0.0021 17.8 1.1 0.0044 16.7 0.0 2.0 2 0 0 2 2 2 1 SAP domain Glyco_transf_49 PF13896.6 KXZ47363.1 - 1.4e-33 116.7 0.0 2e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan MGDG_synth PF06925.11 KXZ47364.1 - 9.1e-39 133.3 0.0 1.2e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 KXZ47364.1 - 2.2e-11 44.0 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 KXZ47364.1 - 7.6e-05 23.2 0.4 0.0097 16.4 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KXZ47364.1 - 9.6e-05 22.4 0.3 0.0097 15.9 0.1 2.7 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXZ47364.1 - 0.0036 17.7 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 PHR PF08005.12 KXZ47365.1 - 7.8e-20 72.1 0.0 1.9e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 PHR domain BTB_2 PF02214.22 KXZ47365.1 - 3.1e-16 59.5 0.0 2.4e-14 53.4 0.0 2.8 2 1 0 2 2 2 1 BTB/POZ domain TPR_MLP1_2 PF07926.12 KXZ47365.1 - 0.026 14.6 3.8 0.048 13.7 3.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FliD_N PF02465.18 KXZ47365.1 - 0.076 13.7 0.1 0.12 13.1 0.1 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus eIF-6 PF01912.18 KXZ47366.1 - 1.5e-81 272.5 0.1 2.4e-81 271.9 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family 5_3_exonuc_N PF02739.16 KXZ47367.1 - 3.9e-05 23.6 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KXZ47367.1 - 0.00012 22.6 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold AAA_23 PF13476.6 KXZ47368.1 - 0.015 15.8 0.0 0.033 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain VHS PF00790.19 KXZ47369.1 - 7.5e-09 35.6 0.1 1.8e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 VHS domain RecO_C PF02565.15 KXZ47369.1 - 0.0005 19.9 0.9 0.013 15.3 0.1 2.4 2 0 0 2 2 2 1 Recombination protein O C terminal GAT PF03127.14 KXZ47369.1 - 0.028 14.7 0.8 0.028 14.7 0.8 2.7 3 0 0 3 3 3 0 GAT domain Cyt-b5 PF00173.28 KXZ47370.1 - 2.4e-13 50.0 0.1 4.4e-13 49.2 0.1 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cytochrom_B561 PF03188.16 KXZ47371.1 - 6.8e-33 113.7 1.2 1.1e-32 113.0 1.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Phage_sheath_1 PF04984.14 KXZ47371.1 - 0.15 11.9 1.0 8.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain DUF4079 PF13301.6 KXZ47371.1 - 3 8.0 7.1 1.7 8.8 2.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DAO PF01266.24 KXZ47373.1 - 9.8e-40 137.2 3.3 1.7e-39 136.4 3.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 KXZ47373.1 - 9.3e-13 47.9 1.1 1.8e-12 47.0 1.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 KXZ47373.1 - 5.6e-07 29.7 0.2 5.6e-07 29.7 0.2 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXZ47373.1 - 8.5e-06 25.2 0.4 2.3e-05 23.8 0.5 1.5 1 1 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXZ47373.1 - 1.1e-05 24.9 0.0 2.6e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ47373.1 - 5.6e-05 22.4 3.7 0.0001 21.6 3.7 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KXZ47373.1 - 0.00013 21.3 0.3 0.00024 20.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXZ47373.1 - 0.00018 20.3 0.0 0.00029 19.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXZ47373.1 - 0.00028 21.4 0.4 0.00096 19.7 0.2 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXZ47373.1 - 0.0004 20.3 0.2 0.00089 19.2 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KXZ47373.1 - 0.0023 17.4 0.1 0.0039 16.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KXZ47373.1 - 0.0039 17.6 0.2 0.0092 16.4 0.1 1.6 2 0 0 2 2 1 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 KXZ47373.1 - 0.0042 16.4 0.2 0.0077 15.6 0.2 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KXZ47373.1 - 0.0056 16.0 0.0 0.025 13.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXZ47373.1 - 0.007 16.0 0.8 0.016 14.8 0.8 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KXZ47373.1 - 0.0071 15.5 1.1 0.013 14.6 1.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXZ47373.1 - 0.0083 15.4 0.6 0.022 14.1 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXZ47373.1 - 0.011 14.8 0.1 0.022 13.8 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KXZ47373.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KXZ47373.1 - 0.015 15.5 0.3 0.047 13.9 0.1 2.1 2 0 0 2 2 1 0 TrkA-N domain Shikimate_DH PF01488.20 KXZ47373.1 - 0.032 14.3 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KXZ47373.1 - 0.2 11.1 0.1 0.2 11.1 0.1 1.9 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Rossmann-like PF10727.9 KXZ47373.1 - 0.22 11.4 1.8 0.28 11.0 0.3 1.9 2 0 0 2 2 1 0 Rossmann-like domain NAD_binding_9 PF13454.6 KXZ47373.1 - 0.26 11.3 1.7 0.48 10.4 0.0 2.3 3 0 0 3 3 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 KXZ47373.1 - 0.87 9.5 2.5 0.57 10.2 0.1 1.9 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF72 PF01904.18 KXZ47375.1 - 1.8e-41 142.7 0.0 2.4e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF72 SnoaL_2 PF12680.7 KXZ47377.1 - 3.6e-18 66.1 0.0 6.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXZ47377.1 - 1.9e-07 30.9 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 KXZ47377.1 - 9.9e-07 29.0 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 KXZ47377.1 - 2.5e-05 24.8 0.0 4.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4904 PF16247.5 KXZ47377.1 - 0.00021 21.1 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4904) DUF4440 PF14534.6 KXZ47377.1 - 0.0026 18.1 0.0 0.004 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) PYNP_C PF07831.13 KXZ47377.1 - 0.023 14.4 0.1 0.6 9.8 0.1 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF4829 PF16111.5 KXZ47377.1 - 0.26 12.1 0.0 0.38 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) Pro_isomerase PF00160.21 KXZ47378.1 - 1.3e-34 119.7 0.1 3.8e-23 82.5 0.0 2.2 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CS PF04969.16 KXZ47378.1 - 1.5e-14 54.8 0.0 7.3e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 CS domain DUF4093 PF13331.6 KXZ47380.1 - 5.8e-16 58.7 0.1 1.5e-15 57.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4093) HEAT PF02985.22 KXZ47380.1 - 2e-10 40.0 11.5 0.49 10.8 0.0 7.4 7 0 0 7 7 7 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KXZ47380.1 - 3.8e-08 33.8 0.8 0.19 12.3 0.0 4.7 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KXZ47380.1 - 1.5e-06 28.5 13.3 0.02 15.3 1.5 5.3 5 1 1 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KXZ47380.1 - 0.00014 22.0 4.2 24 4.9 0.1 4.8 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXZ47380.1 - 0.017 13.7 0.4 10 4.5 0.1 3.3 2 1 0 3 3 3 0 Adaptin N terminal region Cohesin_HEAT PF12765.7 KXZ47380.1 - 0.063 13.6 0.1 14 6.1 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KXZ47380.1 - 0.14 12.7 6.4 14 6.4 0.1 4.8 4 0 0 4 4 4 0 HEAT-like repeat Peptidase_M20 PF01546.28 KXZ47381.1 - 3.5e-25 88.9 0.1 1.7e-24 86.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KXZ47381.1 - 5.6e-24 84.0 13.8 0.00026 21.7 0.1 8.4 7 1 0 7 7 7 5 WD domain, G-beta repeat GATase_6 PF13522.6 KXZ47381.1 - 2.9e-10 40.5 0.0 6.8e-09 36.0 0.0 2.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXZ47381.1 - 8.4e-09 34.7 0.0 2.5e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II M20_dimer PF07687.14 KXZ47381.1 - 0.0035 17.2 0.0 0.017 15.0 0.0 2.2 1 1 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 KXZ47381.1 - 0.011 14.4 2.6 0.35 9.4 0.1 3.6 3 1 1 4 4 4 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXZ47381.1 - 0.026 14.8 0.2 67 3.9 0.0 4.7 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Myosin_N PF02736.19 KXZ47386.1 - 0.0041 16.9 0.2 0.011 15.6 0.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GIT_CC PF16559.5 KXZ47386.1 - 0.12 12.3 0.8 0.2 11.6 0.8 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor mRNA_cap_enzyme PF01331.19 KXZ47387.1 - 8.8e-08 32.2 0.0 0.014 15.3 0.0 3.2 3 0 0 3 3 3 3 mRNA capping enzyme, catalytic domain AAA_16 PF13191.6 KXZ47387.1 - 2.7e-06 27.9 0.1 2.7e-06 27.9 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain F-box PF00646.33 KXZ47387.1 - 1.3e-05 24.9 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain AAA_18 PF13238.6 KXZ47387.1 - 0.0004 20.9 0.2 0.0011 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain F-box-like PF12937.7 KXZ47387.1 - 0.0028 17.5 0.1 0.0084 16.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like AAA_22 PF13401.6 KXZ47387.1 - 0.01 16.1 0.0 0.031 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXZ47387.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXZ47387.1 - 0.052 13.7 0.0 0.052 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXZ47387.1 - 0.055 13.7 0.0 0.055 13.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KXZ47387.1 - 0.15 12.5 0.0 0.41 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain FA_hydroxylase PF04116.13 KXZ47388.1 - 1.5e-14 54.4 9.6 1.5e-14 54.4 9.6 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KXZ47388.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region TssN PF17555.2 KXZ47388.1 - 0.35 10.2 2.4 0.61 9.4 2.4 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN Thioredoxin PF00085.20 KXZ47389.1 - 2.4e-12 46.7 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ47389.1 - 0.00015 22.2 1.0 0.00086 19.7 1.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ47389.1 - 0.0014 19.0 0.1 0.009 16.3 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KXZ47389.1 - 0.027 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DUF5575 PF17738.1 KXZ47389.1 - 0.051 12.6 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5575) TraF PF13728.6 KXZ47389.1 - 0.073 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein AAA_30 PF13604.6 KXZ47390.1 - 3.5e-06 26.9 0.3 6.9e-06 25.9 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXZ47390.1 - 3.8e-06 27.4 0.0 6.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KXZ47390.1 - 7e-06 26.1 0.3 0.0097 15.8 0.0 2.4 2 0 0 2 2 2 2 NTPase AAA_16 PF13191.6 KXZ47390.1 - 1.5e-05 25.4 0.0 3.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KXZ47390.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KXZ47390.1 - 0.00033 20.7 0.0 0.00073 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ47390.1 - 0.00053 20.3 0.2 0.0025 18.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXZ47390.1 - 0.00084 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ47390.1 - 0.001 19.6 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ47390.1 - 0.0012 19.2 0.1 0.0045 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXZ47390.1 - 0.0032 17.4 0.0 0.0076 16.2 0.0 1.7 2 0 0 2 2 1 1 NACHT domain AAA_25 PF13481.6 KXZ47390.1 - 0.0037 16.9 1.0 0.083 12.5 0.0 2.6 1 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 KXZ47390.1 - 0.0043 16.0 0.2 0.013 14.4 0.1 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.23 KXZ47390.1 - 0.0051 16.9 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 KXZ47390.1 - 0.0068 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain MeaB PF03308.16 KXZ47390.1 - 0.0073 15.3 0.2 0.012 14.6 0.2 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KXZ47390.1 - 0.0081 15.8 0.2 0.032 13.8 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 KXZ47390.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 KXZ47390.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXZ47390.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.6 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KXZ47390.1 - 0.014 15.9 0.0 0.041 14.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 KXZ47390.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXZ47390.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KXZ47390.1 - 0.022 14.9 0.0 0.067 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ47390.1 - 0.024 14.7 0.1 0.067 13.2 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXZ47390.1 - 0.031 13.5 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KXZ47390.1 - 0.037 13.1 0.3 0.059 12.4 0.3 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 KXZ47390.1 - 0.037 14.3 0.4 7.8 6.7 0.1 2.6 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KXZ47390.1 - 0.038 13.7 0.0 0.079 12.7 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain KTI12 PF08433.10 KXZ47390.1 - 0.059 12.8 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Roc PF08477.13 KXZ47390.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF3606 PF12244.8 KXZ47390.1 - 0.063 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AAA_31 PF13614.6 KXZ47390.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXZ47390.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TniB PF05621.11 KXZ47390.1 - 0.091 12.2 0.2 0.63 9.4 0.2 2.0 1 1 0 1 1 1 0 Bacterial TniB protein IstB_IS21 PF01695.17 KXZ47390.1 - 0.092 12.5 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_3 PF07726.11 KXZ47390.1 - 0.1 12.4 0.1 0.23 11.3 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KXZ47390.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 KXZ47390.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 KXZ47390.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 KXZ47390.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 KXZ47390.1 - 0.19 11.0 0.1 1.8 7.8 0.0 2.0 1 1 1 2 2 2 0 KaiC DEK_C PF08766.11 KXZ47391.1 - 4.5e-09 36.1 0.0 5.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 DEK C terminal domain P4Ha_N PF08336.11 KXZ47391.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HTH_28 PF13518.6 KXZ47391.1 - 0.35 11.0 2.5 0.39 10.9 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain Ribosomal_L12_N PF16320.5 KXZ47391.1 - 2.3 8.0 0.0 2.3 8.0 0.0 3.0 2 1 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain Galactosyl_T PF01762.21 KXZ47393.1 - 7.2e-16 58.6 0.0 1.3e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KXZ47393.1 - 0.0033 16.9 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Fringe-like APG17 PF04108.12 KXZ47394.1 - 0.0013 17.9 3.3 0.0013 17.9 3.3 1.5 2 0 0 2 2 2 1 Autophagy protein Apg17 Apolipoprotein PF01442.18 KXZ47394.1 - 0.23 11.3 21.4 6.8 6.5 21.5 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YqjK PF13997.6 KXZ47394.1 - 3.6 7.9 10.8 1 9.7 1.8 2.6 2 1 0 2 2 2 0 YqjK-like protein DEK_C PF08766.11 KXZ47395.1 - 5.8e-09 35.7 0.2 1.4e-08 34.5 0.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain Enolase_C PF00113.22 KXZ47396.1 - 1.9e-146 487.0 0.1 2.6e-146 486.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KXZ47396.1 - 6.3e-59 197.9 0.2 1.1e-58 197.0 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KXZ47396.1 - 5.6e-08 32.6 0.0 9.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KXZ47396.1 - 1.8e-05 24.0 0.1 3.8e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF5582 PF17819.1 KXZ47396.1 - 0.03 14.8 1.7 0.12 12.8 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5582) Ephrin_rec_like PF07699.13 KXZ47397.1 - 6.9e-11 41.7 20.1 3.4e-07 29.9 3.7 3.4 1 1 2 3 3 3 2 Putative ephrin-receptor like TNFR_c6 PF00020.18 KXZ47397.1 - 0.0032 17.9 7.0 0.81 10.1 0.4 3.4 1 1 2 3 3 3 3 TNFR/NGFR cysteine-rich region 3HCDH_RFF PF18321.1 KXZ47397.1 - 0.0077 16.7 3.4 0.0077 16.7 3.4 3.1 2 0 0 2 2 2 1 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF2318 PF10080.9 KXZ47397.1 - 0.59 10.3 5.2 0.95 9.6 0.7 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Tubulin PF00091.25 KXZ47398.1 - 6.5e-41 140.7 0.0 1.7e-21 77.4 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 KXZ47398.1 - 0.00041 19.6 0.0 0.00073 18.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Suf PF05843.14 KXZ47399.1 - 8.1e-09 35.9 4.7 0.15 12.0 0.1 4.9 4 1 1 5 5 5 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KXZ47399.1 - 1.2e-08 35.0 5.1 1.1 9.3 0.1 7.0 8 0 0 8 8 8 3 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 KXZ47399.1 - 1.2e-07 32.0 45.5 0.27 12.1 0.0 11.9 11 3 2 13 13 13 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ47399.1 - 7.5e-07 29.4 7.0 0.0015 18.8 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KXZ47399.1 - 0.00017 20.8 4.8 0.2 10.8 0.2 5.2 3 2 2 5 5 5 1 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 KXZ47399.1 - 0.014 15.5 6.1 50 4.5 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ47399.1 - 0.17 11.7 5.4 29 4.7 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 KXZ47399.1 - 0.32 10.4 3.8 30 3.9 0.1 3.9 4 1 1 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KXZ47399.1 - 0.69 10.2 24.4 3.5 8.0 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ47399.1 - 4.5 8.1 10.0 4.2 8.2 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC15 PF15243.6 KXZ47401.1 - 7.9e-07 29.4 6.5 8.8e-07 29.2 6.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 Lactamase_B_2 PF12706.7 KXZ47402.1 - 0.0013 18.3 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KXZ47403.1 - 2.1e-18 66.5 0.0 3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase YL1 PF05764.13 KXZ47404.1 - 0.036 14.2 8.2 0.053 13.6 8.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KXZ47404.1 - 1 7.6 3.8 1.3 7.2 3.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXZ47404.1 - 4.4 5.4 6.2 5.9 5.0 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KXZ47404.1 - 8.8 4.8 15.3 13 4.3 15.3 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGS PF05002.15 KXZ47405.1 - 3.1e-34 116.9 0.7 7.9e-34 115.6 0.7 1.7 1 0 0 1 1 1 1 SGS domain TPR_2 PF07719.17 KXZ47405.1 - 1.5e-15 56.0 12.6 2.8e-05 23.9 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ47405.1 - 2.2e-13 49.4 11.9 7.3e-06 25.6 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.16 KXZ47405.1 - 4.5e-12 46.8 0.0 7.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.6 KXZ47405.1 - 1.8e-11 43.5 9.7 9.7e-09 34.8 2.7 3.4 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 KXZ47405.1 - 3.1e-09 36.3 8.5 0.0001 22.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ47405.1 - 5.2e-08 33.3 9.8 9.7e-06 26.0 4.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ47405.1 - 2.4e-07 30.7 3.7 0.0047 17.2 1.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ47405.1 - 8e-07 29.6 15.9 1.2e-05 25.9 4.4 3.4 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ47405.1 - 1.8e-06 28.3 7.1 0.044 14.6 1.2 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ47405.1 - 0.00011 22.3 3.7 0.014 15.6 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ47405.1 - 0.026 14.8 8.2 0.17 12.2 3.6 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ47405.1 - 0.061 14.0 4.6 2.4 9.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ47405.1 - 0.15 12.1 1.9 8.6 6.5 0.0 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KXZ47405.1 - 0.16 12.2 2.2 0.3 11.3 2.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 JmjC PF02373.22 KXZ47406.1 - 5.2e-40 136.4 0.0 1.1e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 KXZ47406.1 - 6.8e-37 127.4 0.0 5.1e-20 71.9 0.0 7.4 5 4 1 6 6 6 5 PLU-1-like protein PHD PF00628.29 KXZ47406.1 - 7.4e-21 73.8 50.4 2.1e-12 46.7 3.4 3.8 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 KXZ47406.1 - 1.2e-18 67.6 0.4 3.4e-18 66.1 0.4 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KXZ47406.1 - 2.1e-12 46.8 0.0 4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KXZ47406.1 - 1.4e-09 38.2 10.6 3e-09 37.1 10.6 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 KXZ47406.1 - 0.51 9.9 16.0 2 8.0 0.4 3.7 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 KXZ47406.1 - 1.8 8.7 27.2 0.032 14.3 3.4 3.4 3 0 0 3 3 3 0 PHD-finger GATase_2 PF00310.21 KXZ47407.1 - 8.9e-166 551.8 0.0 1.1e-165 551.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KXZ47407.1 - 1e-154 515.1 0.6 1.7e-153 511.1 0.2 2.3 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KXZ47407.1 - 1.8e-101 339.3 0.0 4.6e-100 334.7 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KXZ47407.1 - 2.3e-73 245.9 9.7 4.4e-73 244.9 9.7 1.5 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 KXZ47407.1 - 0.00027 20.1 5.3 0.00027 20.1 5.3 2.7 3 0 0 3 3 3 2 FMN-dependent dehydrogenase MinC_C PF03775.16 KXZ47407.1 - 0.88 9.6 4.2 0.83 9.7 0.8 2.4 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain GMC_oxred_N PF00732.19 KXZ47408.1 - 7.7e-71 238.9 0.0 1.1e-70 238.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXZ47408.1 - 1.4e-36 126.1 0.0 2.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXZ47408.1 - 9.9e-05 22.5 0.4 0.00074 19.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ47408.1 - 0.0005 19.8 2.8 0.1 12.2 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXZ47408.1 - 0.0037 16.4 0.2 0.0062 15.6 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXZ47408.1 - 0.011 14.8 0.3 0.027 13.5 0.3 1.6 1 0 0 1 1 1 0 FAD binding domain HicB PF05534.12 KXZ47408.1 - 0.033 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 HicB family Pyr_redox_3 PF13738.6 KXZ47408.1 - 0.07 12.4 0.2 0.22 10.7 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KXZ47408.1 - 0.078 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox_2 PF07992.14 KXZ47408.1 - 0.087 12.0 0.6 0.23 10.7 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ47408.1 - 0.13 12.8 0.0 1.3 9.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TRAM_LAG1_CLN8 PF03798.16 KXZ47409.1 - 6.3e-23 81.5 16.0 8.9e-23 81.1 16.0 1.2 1 0 0 1 1 1 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 KXZ47410.1 - 1.2e-23 83.9 16.1 1.6e-23 83.5 16.1 1.1 1 0 0 1 1 1 1 TLC domain SnoaL_2 PF12680.7 KXZ47411.1 - 0.0056 17.3 0.9 0.22 12.2 0.1 2.2 2 0 0 2 2 2 2 SnoaL-like domain UPF0051 PF01458.17 KXZ47412.1 - 1.7e-53 181.5 0.0 2.2e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF1517 PF07466.11 KXZ47413.1 - 4.2e-21 75.9 0.0 1.1e-20 74.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1517 PF07466.11 KXZ47414.1 - 6.2e-23 81.9 0.2 1.4e-22 80.7 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1517 PF07466.11 KXZ47415.1 - 2.3e-07 31.1 0.1 2.6e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1517 PF07466.11 KXZ47416.1 - 3e-25 89.4 0.0 1.5e-24 87.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1517) Rrn6 PF10214.9 KXZ47416.1 - 4.4 5.7 6.3 5.7 5.3 6.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1517 PF07466.11 KXZ47418.1 - 5.6e-05 23.4 0.1 8e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1517 PF07466.11 KXZ47419.1 - 2.6e-16 60.3 0.3 9e-16 58.5 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1517 PF07466.11 KXZ47421.1 - 6.2e-14 52.5 0.0 7.1e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1517 PF07466.11 KXZ47422.1 - 0.0002 21.6 0.1 0.00022 21.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) GBP_C PF02841.14 KXZ47423.1 - 0.08 12.3 11.6 0.1 12.0 11.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF5521 PF17659.1 KXZ47423.1 - 0.15 9.9 1.0 0.15 9.9 1.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF2828 PF11443.8 KXZ47423.1 - 0.23 9.5 4.4 0.25 9.4 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3464 PF11947.8 KXZ47423.1 - 1.4 8.6 7.1 2.3 7.9 7.1 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EMC3_TMCO1 PF01956.16 KXZ47423.1 - 4.2 7.1 4.9 5.3 6.7 4.9 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 KXZ47423.1 - 4.3 6.0 5.2 4.8 5.8 5.2 1.1 1 0 0 1 1 1 0 Presenilin DUF1517 PF07466.11 KXZ47426.1 - 2e-18 67.2 0.1 4.5e-18 66.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1517) Glutaredoxin PF00462.24 KXZ47427.1 - 2.8e-20 72.3 0.0 4.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KXZ47427.1 - 0.00012 22.5 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXZ47427.1 - 0.045 14.1 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 KXZ47427.1 - 0.1 13.0 0.1 0.16 12.4 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Helicase_C PF00271.31 KXZ47428.1 - 6.2e-24 84.5 0.0 3.4e-23 82.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ47428.1 - 3.3e-20 72.6 0.7 1.6e-18 67.1 0.0 3.0 2 1 1 3 3 3 1 DEAD/DEAH box helicase PAP_fibrillin PF04755.12 KXZ47428.1 - 0.013 15.5 0.0 0.07 13.1 0.0 2.0 1 1 0 1 1 1 0 PAP_fibrillin ResIII PF04851.15 KXZ47428.1 - 0.019 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KXZ47428.1 - 0.022 14.8 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain Pkinase PF00069.25 KXZ47431.1 - 5.1e-07 29.3 0.0 8.4e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ47431.1 - 0.04 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ47431.1 - 0.17 11.2 0.1 0.63 9.3 0.1 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase LAP1C PF05609.12 KXZ47432.1 - 0.022 13.9 13.1 0.027 13.6 13.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SLC12 PF03522.15 KXZ47432.1 - 0.096 11.7 12.9 0.12 11.4 12.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 KXZ47432.1 - 0.11 10.8 29.8 0.12 10.6 29.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4776 PF16003.5 KXZ47432.1 - 1.2 8.1 26.0 1.1 8.2 25.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4776) Neur_chan_memb PF02932.16 KXZ47432.1 - 1.3 9.0 12.3 1.6 8.7 12.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BAF1_ABF1 PF04684.13 KXZ47432.1 - 2.5 7.1 19.7 3 6.8 19.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.6 KXZ47432.1 - 2.6 7.3 29.1 3.4 6.9 29.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2151 PF10221.9 KXZ47432.1 - 2.6 6.5 15.4 4.3 5.8 15.4 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator SRP-alpha_N PF04086.13 KXZ47432.1 - 3.8 7.4 32.1 4.5 7.1 32.1 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GREB1 PF15782.5 KXZ47432.1 - 4.2 4.4 11.1 4.8 4.2 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 KXZ47432.1 - 4.9 5.2 22.5 5.9 4.9 22.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 KXZ47432.1 - 5.2 5.8 16.4 6.3 5.5 16.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Myb_DNA-binding PF00249.31 KXZ47433.1 - 3.4e-06 27.1 0.1 6.2e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 KXZ47433.1 - 0.11 12.6 0.0 0.11 12.6 0.0 7.6 7 1 1 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 FliD_N PF02465.18 KXZ47433.1 - 1.1 10.0 6.6 0.14 12.9 0.5 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF382 PF04037.13 KXZ47434.1 - 1.4e-56 190.1 0.4 1.4e-56 190.1 0.4 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KXZ47434.1 - 7.9e-21 73.7 5.4 1.6e-20 72.7 5.4 1.5 1 0 0 1 1 1 1 PSP AsnC_trans_reg PF01037.21 KXZ47434.1 - 0.16 12.0 0.1 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain Ribosomal_S17_N PF16205.5 KXZ47435.1 - 4.2e-31 107.1 2.9 4.3e-31 107.1 1.9 1.5 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KXZ47435.1 - 1.2e-25 89.4 0.4 1.8e-25 88.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 FPP PF05911.11 KXZ47436.1 - 0.13 10.5 15.9 0.23 9.6 15.9 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil SHE3 PF17078.5 KXZ47436.1 - 1.8 8.2 17.5 0.96 9.1 13.6 2.2 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Kinase-PPPase PF03618.14 KXZ47437.1 - 2e-74 250.6 0.0 1.4e-72 244.6 0.0 2.3 1 1 0 1 1 1 1 Kinase/pyrophosphorylase Rotamase_2 PF13145.6 KXZ47437.1 - 0.21 12.4 3.3 0.24 12.3 0.8 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain SAND PF01342.21 KXZ47438.1 - 3.3e-09 36.3 0.1 4.9e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 SAND domain PHD_2 PF13831.6 KXZ47439.1 - 3.7e-13 48.8 1.0 3.7e-13 48.8 1.0 2.6 3 0 0 3 3 2 1 PHD-finger PHD PF00628.29 KXZ47439.1 - 7.5e-11 41.8 5.0 7.5e-11 41.8 5.0 2.5 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KXZ47439.1 - 4e-09 36.6 4.6 9.6e-08 32.2 0.6 2.2 2 0 0 2 2 2 2 PHD-zinc-finger like domain C1_1 PF00130.22 KXZ47439.1 - 2.5e-05 24.1 0.5 2.5e-05 24.1 0.5 2.8 3 1 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KXZ47439.1 - 0.00011 22.0 5.9 0.00011 22.0 5.9 2.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 KXZ47439.1 - 0.0007 19.8 0.7 0.0013 19.0 0.7 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-PHD-like PF15446.6 KXZ47439.1 - 0.0019 17.8 1.1 0.0038 16.9 1.1 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-RING_9 PF13901.6 KXZ47439.1 - 0.003 17.5 1.4 0.003 17.5 1.4 1.6 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon C1_2 PF03107.16 KXZ47439.1 - 0.041 14.2 2.0 0.041 14.2 2.0 2.6 3 0 0 3 3 2 0 C1 domain zf-HC5HC2H PF13771.6 KXZ47439.1 - 0.055 13.7 6.6 1.2 9.5 0.1 3.0 3 0 0 3 3 3 0 PHD-like zinc-binding domain DUF2318 PF10080.9 KXZ47439.1 - 0.069 13.3 0.5 0.069 13.3 0.5 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) PHF5 PF03660.14 KXZ47439.1 - 0.07 13.3 7.2 0.037 14.2 5.0 1.5 1 1 0 1 1 1 0 PHF5-like protein zf-UDP PF14569.6 KXZ47439.1 - 2.6 8.2 7.7 5.1 7.3 7.6 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger OrfB_Zn_ribbon PF07282.11 KXZ47439.1 - 5.3 7.1 6.5 0.37 10.7 0.9 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain SET PF00856.28 KXZ47440.1 - 5.3e-14 53.0 4.2 1.7e-12 48.0 0.1 3.6 2 2 0 2 2 2 1 SET domain SAND PF01342.21 KXZ47440.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.6 2 0 0 2 2 2 0 SAND domain Citrate_synt PF00285.21 KXZ47443.1 - 1.4e-30 106.6 0.0 5.3e-29 101.4 0.0 2.1 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Citrate_synt PF00285.21 KXZ47444.1 - 6.2e-17 61.7 0.0 6.8e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Smr PF01713.21 KXZ47444.1 - 0.018 15.4 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Smr domain DUF3552 PF12072.8 KXZ47445.1 - 0.0032 16.9 11.0 0.0052 16.2 11.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) NACHT PF05729.12 KXZ47445.1 - 0.038 13.9 0.0 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Atg14 PF10186.9 KXZ47445.1 - 0.094 11.8 3.5 0.15 11.1 3.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 KXZ47445.1 - 0.22 11.7 11.6 0.35 11.1 11.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 AAA_11 PF13086.6 KXZ47445.1 - 0.42 10.3 5.1 27 4.4 5.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0449 PF15136.6 KXZ47445.1 - 0.69 10.4 4.6 1.8 9.1 4.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DLP_helical PF18709.1 KXZ47445.1 - 0.98 8.6 5.8 1.6 7.9 5.8 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain Macoilin PF09726.9 KXZ47445.1 - 1.3 7.5 4.9 1.9 6.9 4.9 1.1 1 0 0 1 1 1 0 Macoilin family Fmp27_WPPW PF10359.9 KXZ47445.1 - 1.8 7.3 4.5 2.5 6.8 4.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain OmpH PF03938.14 KXZ47445.1 - 2.6 8.4 14.5 4.3 7.7 14.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 KXZ47445.1 - 7 7.1 15.7 23 5.4 15.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Ank_2 PF12796.7 KXZ47446.1 - 5.3e-12 46.2 0.1 0.0003 21.3 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47446.1 - 0.00045 20.7 6.3 0.89 10.2 0.1 5.7 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ47446.1 - 0.00089 19.5 0.6 3e+02 2.6 0.0 6.9 7 1 1 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ47446.1 - 0.0071 16.6 1.0 11 6.4 0.0 5.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47448.1 - 5.4e-12 46.1 0.4 0.00075 20.0 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47448.1 - 7.8e-05 22.8 0.7 12 6.8 0.0 6.9 7 1 1 8 8 8 1 Ankyrin repeat Ank_4 PF13637.6 KXZ47448.1 - 8.7e-05 23.0 9.5 0.26 11.9 0.0 6.4 5 3 2 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ47448.1 - 0.099 13.0 2.9 17 5.9 0.0 4.5 5 1 1 6 6 6 0 Ankyrin repeats (many copies) LRR_4 PF12799.7 KXZ47449.1 - 0.16 12.4 5.6 7.8 7.1 0.0 4.9 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ47449.1 - 1.3 8.9 16.9 36 4.2 0.0 6.9 7 0 0 7 7 7 0 Leucine rich repeat AAA_25 PF13481.6 KXZ47450.1 - 2.6e-10 40.2 0.0 7e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KXZ47450.1 - 0.00061 19.2 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_29 PF13555.6 KXZ47450.1 - 0.0086 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 KXZ47450.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 KXZ47450.1 - 0.027 13.8 0.0 0.068 12.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family SWI-SNF_Ssr4 PF08549.10 KXZ47450.1 - 0.12 11.0 3.4 0.17 10.5 3.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) KTI12 PF08433.10 KXZ47450.1 - 0.18 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2283 PF10049.9 KXZ47451.1 - 4.2e-06 26.9 0.0 8.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2283) zf-Tim10_DDP PF02953.15 KXZ47452.1 - 1.1e-06 28.1 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DCA16 PF15349.6 KXZ47452.1 - 0.02 14.4 0.1 0.021 14.4 0.1 1.0 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Trp_halogenase PF04820.14 KXZ47452.1 - 0.14 11.0 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Tryptophan halogenase HSP90 PF00183.18 KXZ47453.1 - 6.4e-65 220.0 7.8 2.1e-42 145.7 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 KXZ47453.1 - 1.1e-08 35.5 0.0 1.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXZ47453.1 - 8.3e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BNIP3 PF06553.12 KXZ47453.1 - 0.18 11.4 2.8 0.34 10.6 2.8 1.3 1 0 0 1 1 1 0 BNIP3 zf-MYND PF01753.18 KXZ47454.1 - 3.9e-06 26.8 9.2 8e-06 25.8 9.2 1.5 1 0 0 1 1 1 1 MYND finger Maf PF02545.14 KXZ47455.1 - 2.3e-18 66.6 0.0 3.3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein YbaB_DNA_bd PF02575.16 KXZ47455.1 - 0.033 14.4 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family DUF3348 PF11828.8 KXZ47455.1 - 0.076 12.7 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Citrate_synt PF00285.21 KXZ47456.1 - 4e-106 355.1 0.0 4.8e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Citrate_synt PF00285.21 KXZ47458.1 - 2.8e-100 335.9 0.0 6e-99 331.5 0.0 2.0 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain DUF2300 PF10062.9 KXZ47458.1 - 0.18 11.9 0.3 5.3 7.1 0.2 2.4 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) Citrate_synt PF00285.21 KXZ47459.1 - 2.6e-110 368.9 0.0 3.1e-110 368.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Abhydrolase_6 PF12697.7 KXZ47460.1 - 1.8e-24 87.6 14.4 2.8e-24 87.0 14.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ47460.1 - 2.3e-19 70.1 0.0 1.2e-13 51.4 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ47460.1 - 5.8e-15 55.2 0.0 3.7e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KXZ47460.1 - 0.00015 20.6 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 2 Ndr family Abhydrolase_4 PF08386.10 KXZ47460.1 - 0.00022 21.3 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 KXZ47460.1 - 0.0019 18.4 0.0 0.0047 17.1 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.13 KXZ47460.1 - 0.002 18.0 0.9 0.17 11.8 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KXZ47460.1 - 0.0072 16.1 0.0 0.031 14.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KXZ47460.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase LIDHydrolase PF10230.9 KXZ47460.1 - 0.036 13.6 0.0 8.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase UPF0227 PF05728.12 KXZ47460.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pkinase PF00069.25 KXZ47461.1 - 1.7e-66 224.3 0.0 2.6e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47461.1 - 3.3e-44 151.1 0.0 5.3e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IFT57 PF10498.9 KXZ47461.1 - 3.7e-31 108.4 0.0 6e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Kinase-like PF14531.6 KXZ47461.1 - 5e-06 26.0 0.0 9.8e-06 25.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ47461.1 - 0.0002 20.3 0.0 0.00047 19.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXZ47461.1 - 0.024 14.0 0.1 0.024 14.0 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF773 PF05600.12 KXZ47461.1 - 0.025 13.3 0.9 0.037 12.8 0.9 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Haspin_kinase PF12330.8 KXZ47461.1 - 0.027 13.4 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3450 PF11932.8 KXZ47461.1 - 0.028 13.7 6.3 0.054 12.8 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 KXZ47461.1 - 0.043 14.1 6.8 0.14 12.5 6.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) EzrA PF06160.12 KXZ47461.1 - 0.15 10.2 1.7 0.26 9.4 1.7 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4795 PF16043.5 KXZ47461.1 - 0.21 11.2 6.3 0.41 10.2 5.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 KXZ47461.1 - 0.47 9.3 6.9 0.46 9.3 4.3 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KXZ47461.1 - 0.5 10.4 2.6 2.7 8.0 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 KXZ47461.1 - 2.3 7.9 8.9 9.7 5.9 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) LRR_6 PF13516.6 KXZ47462.1 - 0.0052 16.7 5.7 16 5.8 0.3 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 KXZ47462.1 - 0.056 13.9 10.4 12 6.5 0.6 3.9 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) FPL PF09758.9 KXZ47463.1 - 1.6e-58 196.9 1.9 2.3e-58 196.4 1.9 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein TRPM_tetra PF16519.5 KXZ47463.1 - 0.092 12.9 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Tetramerisation domain of TRPM CCDC-167 PF15188.6 KXZ47464.1 - 0.00092 19.5 3.3 0.00092 19.5 3.3 2.2 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 167 Baculo_PEP_C PF04513.12 KXZ47464.1 - 0.015 15.3 1.5 0.015 15.3 1.5 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus T2SSE PF00437.20 KXZ47464.1 - 0.034 13.2 0.1 0.06 12.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Golgin_A5 PF09787.9 KXZ47464.1 - 0.1 12.1 12.6 0.13 11.7 12.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 MeaB PF03308.16 KXZ47464.1 - 0.13 11.2 0.0 0.31 10.0 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HlyD_2 PF12700.7 KXZ47464.1 - 0.47 9.1 4.1 0.64 8.7 4.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Prominin PF05478.11 KXZ47464.1 - 0.53 8.2 4.6 0.66 7.9 4.6 1.1 1 0 0 1 1 1 0 Prominin FlaC_arch PF05377.11 KXZ47464.1 - 1.9 8.9 6.0 5.7 7.4 0.1 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KXZ47464.1 - 2.1 8.4 8.2 0.55 10.3 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 KXZ47464.1 - 2.7 7.8 15.2 4.2 7.2 15.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 KXZ47464.1 - 4.6 5.8 9.6 10 4.6 9.6 1.5 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KXZ47464.1 - 6.3 6.3 7.5 9.7 5.7 7.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit VOMI PF03762.17 KXZ47465.1 - 2.1e-19 70.3 3.7 2.5e-17 63.5 0.6 2.4 1 1 1 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) PTCB-BRCT PF12738.7 KXZ47467.1 - 2.5e-27 94.6 0.5 9.3e-16 57.5 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KXZ47467.1 - 1.2e-16 60.9 0.0 2.2e-08 34.4 0.0 4.1 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXZ47467.1 - 3.6e-12 46.5 0.0 0.0047 17.3 0.0 3.6 3 1 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KXZ47467.1 - 0.011 15.8 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PCNA_N PF00705.18 KXZ47468.1 - 6.8e-56 187.4 1.5 1.1e-55 186.8 1.5 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KXZ47468.1 - 1e-50 171.2 0.0 1.9e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KXZ47468.1 - 8.1e-07 28.7 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KXZ47468.1 - 1.2e-05 24.6 0.1 0.002 17.3 0.1 2.3 1 1 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KXZ47468.1 - 0.01 15.0 0.0 0.026 13.7 0.0 1.6 1 1 0 2 2 2 0 Hus1-like protein Bac_A_amyl_C PF18612.1 KXZ47468.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain MFS_1 PF07690.16 KXZ47469.1 - 9.9e-38 130.0 25.4 9.9e-38 130.0 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXZ47469.1 - 2.3e-07 29.5 0.4 3.6e-06 25.6 0.0 2.7 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXZ47469.1 - 0.00037 19.5 3.6 0.00037 19.5 3.6 3.3 3 1 1 4 4 4 3 Sugar (and other) transporter UQ_con PF00179.26 KXZ47470.1 - 1.1e-43 148.2 0.0 1.2e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXZ47470.1 - 2.5e-05 24.0 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXZ47470.1 - 0.0096 16.2 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain DUF629 PF04780.12 KXZ47471.1 - 3.8e-08 32.3 0.0 3.8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF629) ZZ PF00569.17 KXZ47471.1 - 0.72 9.7 11.1 0.031 14.1 4.8 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type NCD3G PF07562.14 KXZ47471.1 - 8.1 6.5 6.7 20 5.3 1.6 2.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Sec1 PF00995.23 KXZ47472.1 - 4.1e-79 267.3 0.0 6.6e-78 263.4 0.0 2.0 1 1 0 1 1 1 1 Sec1 family CSN8_PSD8_EIF3K PF10075.9 KXZ47474.1 - 4.7e-19 68.8 0.0 2e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family CAAD PF14159.6 KXZ47476.1 - 0.0053 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase NRBF2 PF08961.10 KXZ47476.1 - 0.05 13.2 0.9 0.14 11.7 0.9 1.7 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator NIPSNAP PF07978.13 KXZ47477.1 - 1.7e-08 34.6 0.1 0.00081 19.6 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP FHA PF00498.26 KXZ47478.1 - 1.1e-15 57.7 0.0 2.5e-15 56.6 0.0 1.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KXZ47478.1 - 0.00097 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ORMDL PF04061.14 KXZ47479.1 - 3.3e-44 150.0 1.4 3.8e-44 149.8 1.4 1.0 1 0 0 1 1 1 1 ORMDL family Acetyltransf_1 PF00583.25 KXZ47480.1 - 1.6e-06 28.4 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ47480.1 - 4.9e-06 26.5 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ47480.1 - 0.00043 20.2 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXZ47480.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXZ47480.1 - 0.026 14.7 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.27 KXZ47481.1 - 1.1e-62 211.1 0.2 2.1e-62 210.1 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXZ47481.1 - 5.9e-32 110.0 0.0 2e-31 108.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXZ47481.1 - 8e-19 67.5 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KXZ47481.1 - 4.5e-15 55.5 0.2 1.7e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KXZ47481.1 - 4.5e-12 46.2 0.1 1.1e-11 45.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ47481.1 - 0.0045 17.1 0.1 0.0092 16.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF771 PF05595.11 KXZ47481.1 - 0.084 12.8 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF771) TPR_2 PF07719.17 KXZ47482.1 - 8.8e-08 31.7 12.5 0.0016 18.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ47482.1 - 1.3e-06 28.8 13.1 6.5e-05 23.4 8.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ47482.1 - 2.5e-06 27.1 5.5 0.0003 20.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ47482.1 - 5.9e-05 23.6 3.2 5.9e-05 23.6 3.2 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ47482.1 - 0.0021 18.7 16.0 0.0021 18.7 16.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ47482.1 - 0.0029 17.7 10.4 0.0029 17.7 10.4 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ47482.1 - 0.0072 16.6 2.9 0.037 14.4 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ47482.1 - 0.13 12.0 0.2 0.13 12.0 0.2 2.9 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 KXZ47482.1 - 0.55 10.6 3.5 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ47482.1 - 1.7 8.6 16.3 0.45 10.5 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Cullin PF00888.22 KXZ47484.1 - 2.2e-41 142.2 0.0 3.8e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXZ47484.1 - 8.7e-23 80.1 0.3 1.6e-22 79.3 0.3 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4494 PF14902.6 KXZ47484.1 - 0.028 14.2 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) TPR_17 PF13431.6 KXZ47484.1 - 0.095 13.1 0.2 0.22 12.0 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cas_Cas5d PF09704.10 KXZ47484.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) Glyco_trans_1_4 PF13692.6 KXZ47485.1 - 1.7e-08 34.9 0.0 3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXZ47485.1 - 1.8e-07 31.8 3.2 1.8e-07 31.8 3.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KXZ47485.1 - 8.5e-07 29.1 0.9 1.8e-06 28.1 0.9 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KXZ47485.1 - 6e-06 25.9 0.0 9.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXZ47485.1 - 3.2e-05 24.3 0.0 0.00027 21.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 SAS-6_N PF16531.5 KXZ47486.1 - 1.1e-25 90.1 0.0 2.5e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Taxilin PF09728.9 KXZ47486.1 - 0.0002 20.7 37.3 0.0002 20.7 37.3 2.2 1 1 1 2 2 2 1 Myosin-like coiled-coil protein FPP PF05911.11 KXZ47486.1 - 0.0017 16.7 24.3 0.0017 16.7 24.3 2.1 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil Filament PF00038.21 KXZ47486.1 - 0.0072 15.9 45.9 0.13 11.8 14.4 4.2 1 1 3 4 4 4 3 Intermediate filament protein TPR_MLP1_2 PF07926.12 KXZ47486.1 - 0.055 13.5 58.4 0.034 14.2 14.7 4.6 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein MADF_DNA_bdg PF10545.9 KXZ47486.1 - 0.2 12.0 3.2 0.57 10.5 0.4 3.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spc7 PF08317.11 KXZ47486.1 - 0.21 10.5 53.3 0.036 13.0 15.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein TSC22 PF01166.18 KXZ47486.1 - 0.26 11.6 14.2 1.8 8.9 0.1 5.0 4 1 1 5 5 4 0 TSC-22/dip/bun family Uso1_p115_C PF04871.13 KXZ47486.1 - 0.45 10.9 51.9 0.49 10.8 12.7 4.3 2 1 2 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 KXZ47486.1 - 1.4 9.3 11.4 2.3 8.6 0.4 5.0 3 2 3 6 6 6 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 KXZ47486.1 - 2.4 8.4 26.2 0.071 13.3 3.3 4.0 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II HOOK PF05622.12 KXZ47486.1 - 4.7 5.2 50.8 1.1 7.3 15.9 2.9 1 1 2 3 3 3 0 HOOK protein Fez1 PF06818.15 KXZ47486.1 - 5.4 7.4 51.0 0.85 10.0 22.2 3.4 1 1 1 3 3 3 0 Fez1 GAS PF13851.6 KXZ47486.1 - 9 5.6 49.7 0.18 11.1 3.2 4.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding F-box PF00646.33 KXZ47487.1 - 8.8e-06 25.5 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXZ47487.1 - 0.00085 19.2 0.2 0.0015 18.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like Lig_chan PF00060.26 KXZ47488.1 - 4.2e-13 49.4 0.5 7e-13 48.7 0.5 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KXZ47488.1 - 4.8e-11 42.5 0.0 7.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 MpPF26 PF07666.11 KXZ47488.1 - 0.17 12.0 4.8 1.2 9.2 1.4 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 Pkinase PF00069.25 KXZ47489.1 - 2.3e-35 122.2 0.0 2.5e-24 86.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47489.1 - 2.8e-32 112.0 0.0 4.8e-32 111.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ47489.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ47489.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ47490.1 - 3.1e-35 121.8 0.0 2.6e-24 86.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47490.1 - 1.2e-30 106.7 0.0 3.1e-30 105.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ47490.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXZ47490.1 - 0.18 11.4 0.0 5 6.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXZ47490.1 - 0.25 10.1 0.0 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SHIPPO-rpt PF07004.12 KXZ47491.1 - 1.8e-07 31.7 26.4 0.22 12.5 0.3 6.4 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat Herpes_LP PF03363.13 KXZ47491.1 - 0.023 14.5 6.1 0.56 10.0 0.5 2.3 2 0 0 2 2 2 0 Herpesvirus leader protein Chalcone_2 PF16035.5 KXZ47492.1 - 2.4e-10 40.5 0.0 1.8e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone PF02431.15 KXZ47492.1 - 3.7e-08 33.0 0.0 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Chalcone_3 PF16036.5 KXZ47492.1 - 1.4e-06 28.5 0.0 0.00017 21.7 0.0 2.7 1 1 0 1 1 1 1 Chalcone isomerase-like PAPS_reduct PF01507.19 KXZ47493.1 - 2e-40 138.7 0.0 4.2e-40 137.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 KXZ47493.1 - 2e-11 43.8 0.0 4.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ47493.1 - 0.00012 22.4 0.1 0.0022 18.4 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KXZ47493.1 - 0.016 15.1 0.5 0.036 13.9 0.0 1.8 2 1 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 KXZ47493.1 - 0.023 14.9 0.6 0.099 12.9 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_9 PF14595.6 KXZ47493.1 - 0.041 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin zf-MYND PF01753.18 KXZ47496.1 - 2.7e-07 30.5 10.6 4.4e-07 29.9 10.6 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ47497.1 - 8.5e-06 25.8 9.6 8.5e-06 25.8 9.6 1.9 2 0 0 2 2 2 1 MYND finger EF-hand_1 PF00036.32 KXZ47498.1 - 0.001 18.4 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ47498.1 - 0.0012 18.3 0.1 0.0027 17.2 0.1 1.5 1 0 0 1 1 1 1 EF hand DUF3537 PF12056.8 KXZ47498.1 - 0.013 14.3 6.2 0.13 11.1 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3537) EF-hand_7 PF13499.6 KXZ47498.1 - 0.025 15.0 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KXZ47498.1 - 0.054 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 KXZ47498.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair GDP_Man_Dehyd PF16363.5 KXZ47499.1 - 2.6e-31 109.2 0.0 5.8e-31 108.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXZ47499.1 - 7.3e-31 107.5 0.0 1e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXZ47499.1 - 1.7e-05 24.1 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXZ47499.1 - 3.1e-05 23.1 0.0 5.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXZ47499.1 - 0.00056 19.2 0.0 0.0023 17.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KXZ47499.1 - 0.0016 17.6 0.0 0.0078 15.4 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXZ47499.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXZ47500.1 - 1e-52 178.9 0.0 3.1e-24 85.4 0.0 3.1 3 0 0 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXZ47500.1 - 1.5e-21 77.0 0.2 6.5e-10 38.9 0.0 3.2 3 0 0 3 3 3 3 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ47500.1 - 9.8e-14 51.5 0.3 0.00023 20.7 0.0 4.1 4 0 0 4 4 4 4 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXZ47500.1 - 5.2e-13 49.3 0.1 1.2e-09 38.4 0.0 2.5 2 0 0 2 2 2 2 NAD(P)H-binding NAD_binding_4 PF07993.12 KXZ47500.1 - 7.1e-09 35.2 0.0 6e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KXZ47500.1 - 6.7e-08 32.0 0.0 1.6e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXZ47500.1 - 0.00045 19.4 0.1 0.061 12.4 0.1 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 KXZ47500.1 - 0.00088 18.9 0.1 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 KXZ47500.1 - 0.0013 18.7 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 1 KR domain Glyco_transf_4 PF13439.6 KXZ47500.1 - 0.06 13.4 5.9 0.19 11.7 0.1 3.6 4 0 0 4 4 4 0 Glycosyltransferase Family 4 UDPG_MGDP_dh_N PF03721.14 KXZ47500.1 - 0.24 11.0 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-U1 PF06220.12 KXZ47502.1 - 3.7e-06 26.6 2.2 6e-06 25.9 2.2 1.3 1 0 0 1 1 1 1 U1 zinc finger Pkinase PF00069.25 KXZ47503.1 - 2.1e-28 99.4 0.0 2.9e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47503.1 - 1e-27 97.1 0.0 1.3e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ47503.1 - 0.00057 19.9 0.5 0.0026 17.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ47503.1 - 0.0011 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXZ47503.1 - 0.29 10.0 0.0 0.42 9.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KXZ47504.1 - 7.8e-29 100.7 0.0 1e-13 51.2 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ47504.1 - 6.8e-25 87.9 0.0 1.1e-15 57.8 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain APH PF01636.23 KXZ47504.1 - 0.061 13.2 0.6 0.099 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family AF-4 PF05110.13 KXZ47504.1 - 0.093 10.8 3.4 0.13 10.3 3.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA PF00004.29 KXZ47505.1 - 1.9e-44 151.3 0.1 9.4e-44 149.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXZ47505.1 - 5.3e-10 39.1 0.1 4.1e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KXZ47505.1 - 9.8e-09 35.3 0.2 3.5e-08 33.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KXZ47505.1 - 3.7e-08 33.1 0.0 8.3e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXZ47505.1 - 2.7e-07 31.1 0.4 5.5e-05 23.6 0.0 2.8 2 2 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KXZ47505.1 - 6.1e-07 29.7 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KXZ47505.1 - 5.4e-06 25.8 0.1 3.5e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXZ47505.1 - 3.9e-05 23.4 0.0 0.00016 21.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ47505.1 - 8.5e-05 22.8 2.9 0.0085 16.4 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KXZ47505.1 - 0.00019 22.0 0.0 0.0007 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXZ47505.1 - 0.00025 20.8 0.3 0.0015 18.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 KXZ47505.1 - 0.00047 20.4 0.2 0.0011 19.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KXZ47505.1 - 0.0007 19.4 0.0 0.0021 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXZ47505.1 - 0.0011 18.2 0.0 0.0027 17.0 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KXZ47505.1 - 0.0012 19.2 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 KXZ47505.1 - 0.0015 17.9 0.1 0.0034 16.8 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXZ47505.1 - 0.0016 18.1 0.1 0.14 11.9 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 KXZ47505.1 - 0.0028 17.7 0.0 0.0064 16.5 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXZ47505.1 - 0.003 17.6 0.1 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXZ47505.1 - 0.0034 17.6 0.0 0.0076 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXZ47505.1 - 0.0049 16.6 0.1 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXZ47505.1 - 0.0057 16.2 2.0 0.022 14.3 0.2 2.3 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 KXZ47505.1 - 0.0086 15.5 0.0 1.3 8.4 0.0 2.7 3 0 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 KXZ47505.1 - 0.0093 15.5 0.1 0.059 12.9 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KXZ47505.1 - 0.013 15.5 0.2 0.081 12.8 0.1 2.4 3 0 0 3 3 2 0 NACHT domain Parvo_NS1 PF01057.17 KXZ47505.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 KXZ47505.1 - 0.018 15.0 0.0 0.046 13.6 0.0 1.8 2 0 0 2 2 1 0 NTPase AAA_3 PF07726.11 KXZ47505.1 - 0.026 14.4 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KXZ47505.1 - 0.035 14.0 0.6 1.8 8.4 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KXZ47505.1 - 0.063 12.6 1.4 0.43 9.9 0.0 2.4 3 0 0 3 3 3 0 KaiC PhoH PF02562.16 KXZ47505.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 KXZ47505.1 - 0.082 13.4 2.2 9.5 6.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXZ47505.1 - 0.085 12.6 0.1 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXZ47505.1 - 0.1 13.0 0.2 0.56 10.5 0.1 2.2 3 0 0 3 3 1 0 AAA domain NB-ARC PF00931.22 KXZ47505.1 - 0.13 11.4 0.0 0.4 9.8 0.0 1.8 2 0 0 2 2 1 0 NB-ARC domain V_ATPase_I PF01496.19 KXZ47506.1 - 5.6e-291 967.3 0.0 6.3e-291 967.1 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GRP PF07172.11 KXZ47506.1 - 0.00088 19.9 4.3 0.0021 18.7 4.3 1.6 1 0 0 1 1 1 1 Glycine rich protein family CCDC73 PF15818.5 KXZ47506.1 - 0.082 10.8 0.3 0.12 10.2 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family DHR10 PF18595.1 KXZ47506.1 - 0.13 12.4 9.3 1.8 8.6 0.3 2.8 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain ABC_tran_CTD PF16326.5 KXZ47506.1 - 0.33 11.2 2.9 0.46 10.8 1.4 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 KXZ47506.1 - 0.58 10.7 5.8 0.21 12.1 2.2 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Filament PF00038.21 KXZ47506.1 - 1.9 8.0 7.0 0.13 11.8 1.9 1.6 2 0 0 2 2 2 0 Intermediate filament protein FAD_binding_3 PF01494.19 KXZ47507.1 - 2e-10 40.5 0.1 3.2e-06 26.7 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Peptidase_C97 PF05903.14 KXZ47508.1 - 0.0047 16.8 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXZ47508.1 - 0.16 12.3 0.1 0.52 10.6 0.1 1.9 1 1 0 1 1 1 0 Lecithin retinol acyltransferase ATG16 PF08614.11 KXZ47509.1 - 1.8 8.8 5.1 2.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FHA PF00498.26 KXZ47511.1 - 9.3e-05 22.7 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXZ47511.1 - 0.0078 16.5 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CBS PF00571.28 KXZ47514.1 - 3.6e-06 27.3 0.3 5.7e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 CBS domain Voltage_CLC PF00654.20 KXZ47515.1 - 1e-17 64.4 4.1 1e-17 64.4 4.1 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel Phage_holin_3_6 PF07332.11 KXZ47515.1 - 4.8 7.3 9.0 0.18 11.8 3.3 1.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RibD_C PF01872.17 KXZ47517.1 - 1.1e-12 48.2 1.1 1.5e-06 28.2 1.1 2.6 3 0 0 3 3 3 2 RibD C-terminal domain DHFR_1 PF00186.19 KXZ47517.1 - 0.035 13.8 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrofolate reductase RIBIOP_C PF04950.12 KXZ47518.1 - 1.1e-73 248.2 0.3 1.1e-71 241.7 0.0 2.4 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXZ47518.1 - 2.3e-29 101.3 0.0 5.7e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KXZ47518.1 - 2.5e-06 28.0 0.0 1.1e-05 25.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXZ47518.1 - 0.0011 19.3 0.2 0.003 17.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 KXZ47518.1 - 0.0028 17.2 0.0 0.027 14.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KXZ47518.1 - 0.0042 17.3 3.7 0.083 13.1 0.0 3.5 4 0 0 4 4 3 1 AAA domain Rad17 PF03215.15 KXZ47518.1 - 0.0051 16.8 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_19 PF13245.6 KXZ47518.1 - 0.008 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXZ47518.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXZ47518.1 - 0.015 15.8 1.7 0.033 14.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXZ47518.1 - 0.024 14.7 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 KXZ47518.1 - 0.03 13.5 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KXZ47518.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KXZ47518.1 - 0.055 14.0 0.5 0.13 12.8 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_11 PF13086.6 KXZ47518.1 - 0.059 13.1 0.0 0.059 13.1 0.0 3.2 2 1 1 3 3 2 0 AAA domain NTPase_1 PF03266.15 KXZ47518.1 - 0.074 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KXZ47518.1 - 0.075 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 KXZ47518.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 KXZ47518.1 - 0.088 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KXZ47518.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 KXZ47518.1 - 0.21 10.4 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein SMC_hinge PF06470.13 KXZ47519.1 - 5e-26 91.3 0.0 1e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 KXZ47519.1 - 1.1e-16 61.0 4.1 1.1e-16 61.0 4.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Lectin_N PF03954.14 KXZ47519.1 - 0.86 9.3 6.0 19 5.0 0.2 3.4 3 1 1 4 4 4 0 Hepatic lectin, N-terminal domain Spc7 PF08317.11 KXZ47519.1 - 1.1 8.1 35.7 0.28 10.0 13.2 3.7 1 1 2 3 3 3 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KXZ47519.1 - 3.7 7.3 27.1 0.12 12.1 11.6 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH SMC_N PF02463.19 KXZ47520.1 - 8.8e-26 90.7 0.1 1.3e-24 86.8 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXZ47520.1 - 2.2e-09 37.6 0.0 3.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase_Tyr PF07714.17 KXZ47521.1 - 5.4e-43 147.1 0.0 7.8e-35 120.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47521.1 - 3.5e-40 138.0 0.0 5.8e-31 107.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ47521.1 - 2.6e-05 23.2 0.0 3.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ47521.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ47521.1 - 0.029 13.7 0.0 0.062 12.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tcf25 PF04910.14 KXZ47521.1 - 0.22 10.6 0.1 2.8 6.9 0.0 2.0 2 0 0 2 2 2 0 Transcriptional repressor TCF25 NT-C2 PF10358.9 KXZ47522.1 - 1.8e-08 34.2 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 KXZ47522.1 - 0.00058 20.1 0.0 0.0027 18.0 0.0 2.0 1 1 0 1 1 1 1 DIL domain MatE PF01554.18 KXZ47523.1 - 4.1e-32 111.1 18.7 6.6e-16 58.4 4.6 2.7 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ47523.1 - 5.6 7.0 27.5 2.1 8.4 11.6 4.0 3 1 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Jiv90 PF14901.6 KXZ47524.1 - 1.1e-16 60.8 1.2 1.8e-16 60.0 1.2 1.4 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone DnaJ PF00226.31 KXZ47524.1 - 1.2e-10 41.3 0.0 4.6e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain PIH1_CS PF18201.1 KXZ47524.1 - 1.2e-07 32.0 0.0 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain TPR_9 PF13371.6 KXZ47524.1 - 0.065 13.4 5.6 0.17 12.1 5.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1635 PF07795.11 KXZ47524.1 - 4.4 7.1 8.7 0.12 12.2 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) AAA PF00004.29 KXZ47525.1 - 5.1e-53 179.0 0.0 5.2e-43 146.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ47525.1 - 4e-08 33.3 0.1 0.015 15.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXZ47525.1 - 1.5e-07 31.3 0.0 0.00059 19.6 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ47525.1 - 1.5e-07 31.9 11.5 0.0018 18.7 0.1 4.5 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KXZ47525.1 - 3.2e-06 27.4 0.1 0.0072 16.6 0.0 3.3 3 1 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 KXZ47525.1 - 3.6e-05 23.2 0.7 0.015 14.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXZ47525.1 - 4.8e-05 23.9 0.0 0.24 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXZ47525.1 - 0.00012 21.8 2.2 0.016 14.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ47525.1 - 0.00012 22.4 0.0 0.025 14.9 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KXZ47525.1 - 0.00013 22.2 0.1 0.084 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KXZ47525.1 - 0.00032 20.7 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KXZ47525.1 - 0.00043 19.6 0.1 0.035 13.3 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KXZ47525.1 - 0.0013 18.5 0.2 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 KXZ47525.1 - 0.0026 18.2 0.1 1.5 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KXZ47525.1 - 0.0037 17.1 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXZ47525.1 - 0.005 16.8 0.1 0.4 10.6 0.0 2.8 3 0 0 3 3 3 1 NACHT domain Rad17 PF03215.15 KXZ47525.1 - 0.0055 16.6 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KXZ47525.1 - 0.0068 16.7 0.1 0.7 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXZ47525.1 - 0.007 15.9 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_2 PF07724.14 KXZ47525.1 - 0.0077 16.4 0.0 0.071 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 KXZ47525.1 - 0.0084 15.5 0.0 0.029 13.7 0.0 1.7 2 0 0 2 2 2 1 KaiC Sigma54_activ_2 PF14532.6 KXZ47525.1 - 0.011 15.9 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXZ47525.1 - 0.011 15.0 0.7 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_lid_3 PF17862.1 KXZ47525.1 - 0.012 15.4 1.7 0.3 10.9 0.0 2.8 2 0 0 2 2 2 0 AAA+ lid domain AAA_19 PF13245.6 KXZ47525.1 - 0.02 15.2 1.6 6.2 7.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KXZ47525.1 - 0.03 14.0 0.0 0.51 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXZ47525.1 - 0.039 13.7 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXZ47525.1 - 0.068 13.1 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 KXZ47525.1 - 0.099 11.8 0.0 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 KXZ47525.1 - 0.11 12.2 0.8 2.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 KXZ47525.1 - 0.12 12.8 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KXZ47525.1 - 0.13 12.0 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain CDC48_2 PF02933.17 KXZ47525.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 NB-ARC PF00931.22 KXZ47525.1 - 0.21 10.8 0.0 1.1 8.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 KXZ47525.1 - 0.21 11.0 1.2 0.61 9.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 KXZ47525.1 - 0.24 10.4 0.0 1.6 7.8 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Parvo_NS1 PF01057.17 KXZ47525.1 - 0.37 9.8 0.1 0.72 8.9 0.0 1.4 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 CytB6-F_Fe-S PF08802.10 KXZ47526.1 - 5.3 7.2 6.8 0.68 10.0 2.3 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Glyco_transf_92 PF01697.27 KXZ47527.1 - 2.9e-13 50.1 0.2 3.8e-13 49.7 0.2 1.2 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KXZ47527.1 - 0.002 18.6 0.0 0.0047 17.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Thioredoxin PF00085.20 KXZ47528.1 - 1.2e-23 83.0 0.0 1.3e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ47528.1 - 6.3e-07 29.8 0.0 2.6e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KXZ47528.1 - 2.7e-05 24.2 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KXZ47528.1 - 6.4e-05 22.9 0.0 7.4e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KXZ47528.1 - 0.00015 22.0 0.0 0.00029 21.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KXZ47528.1 - 0.00099 19.0 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 KXZ47528.1 - 0.0036 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_6 PF13848.6 KXZ47528.1 - 0.0049 16.8 0.0 0.0052 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KXZ47528.1 - 0.058 13.1 0.1 0.1 12.3 0.1 1.5 1 1 1 2 2 2 0 Redoxin ATP-synt_F PF01990.17 KXZ47529.1 - 1.4e-29 102.3 0.1 1.6e-29 102.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit TLD PF07534.16 KXZ47530.1 - 5e-05 23.5 0.0 6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 TLD Response_reg PF00072.24 KXZ47531.1 - 7.5e-09 35.8 0.1 2.4e-08 34.1 0.1 1.8 1 1 0 1 1 1 1 Response regulator receiver domain HOOK PF05622.12 KXZ47531.1 - 0.0054 15.0 0.6 0.0089 14.2 0.6 1.2 1 0 0 1 1 1 1 HOOK protein Cnn_1N PF07989.11 KXZ47531.1 - 0.06 13.5 2.0 0.55 10.4 2.1 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DNA_repr_REX1B PF14966.6 KXZ47531.1 - 0.069 13.8 0.7 0.16 12.7 0.1 1.8 2 0 0 2 2 2 0 DNA repair REX1-B DUF4763 PF15960.5 KXZ47531.1 - 0.29 10.4 4.7 0.075 12.3 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF1465 PF07323.12 KXZ47531.1 - 0.32 10.8 5.0 0.32 10.8 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) CRS1_YhbY PF01985.21 KXZ47531.1 - 0.48 10.6 1.9 0.78 9.9 1.0 1.6 1 1 0 1 1 1 0 CRS1 / YhbY (CRM) domain UPF0242 PF06785.11 KXZ47531.1 - 3.3 7.8 7.3 1.7 8.7 4.3 1.7 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Lzipper-MIP1 PF14389.6 KXZ47531.1 - 6 7.2 11.2 9.6 6.6 0.4 2.9 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 AAA PF00004.29 KXZ47532.1 - 1.6e-37 128.9 0.0 2.4e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ47532.1 - 2.2e-10 40.1 0.0 6.7e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXZ47532.1 - 1.2e-05 25.2 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ47532.1 - 0.00033 21.1 0.0 0.00088 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KXZ47532.1 - 0.00069 18.9 0.0 0.001 18.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KXZ47532.1 - 0.0013 18.7 0.0 0.0036 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXZ47532.1 - 0.0014 18.4 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ47532.1 - 0.0026 18.0 0.1 0.017 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXZ47532.1 - 0.0055 16.7 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXZ47532.1 - 0.0092 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXZ47532.1 - 0.0098 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 KXZ47532.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXZ47532.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KXZ47532.1 - 0.013 15.2 0.0 0.66 9.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 KXZ47532.1 - 0.019 15.1 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ47532.1 - 0.021 14.4 2.6 0.1 12.2 0.4 2.5 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KXZ47532.1 - 0.024 15.2 0.0 0.068 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXZ47532.1 - 0.077 12.1 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KXZ47532.1 - 0.092 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 KXZ47532.1 - 0.098 12.1 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KXZ47532.1 - 0.12 11.7 0.1 0.58 9.5 0.0 1.9 1 1 1 2 2 2 0 KaiC AAA_2 PF07724.14 KXZ47532.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KXZ47532.1 - 0.2 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PsbP PF01789.16 KXZ47533.1 - 7.7e-18 65.1 0.0 8.9e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 PsbP Methyltransf_11 PF08241.12 KXZ47534.1 - 4.1e-10 40.2 0.0 6.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ47534.1 - 2.5e-08 34.5 0.0 4.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ47534.1 - 1.5e-07 31.3 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ47534.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ47534.1 - 0.00058 20.6 0.0 0.001 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KXZ47534.1 - 0.0064 16.2 0.0 0.027 14.1 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 KXZ47534.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KXZ47534.1 - 0.22 10.0 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF4611 PF15387.6 KXZ47535.1 - 0.12 12.6 0.6 0.24 11.6 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ank_2 PF12796.7 KXZ47536.1 - 4.6e-40 136.1 1.5 2e-14 53.9 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 KXZ47536.1 - 1.5e-28 99.6 1.4 2.6e-28 98.8 1.4 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KXZ47536.1 - 5.2e-25 87.5 0.9 1.1e-05 25.8 0.1 5.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ47536.1 - 3.9e-24 84.4 4.4 1.6e-09 37.8 0.4 5.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ47536.1 - 1.2e-23 80.6 0.3 0.001 19.4 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KXZ47536.1 - 6.1e-23 80.2 4.8 9.9e-05 22.6 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat PGG PF13962.6 KXZ47536.1 - 0.075 12.9 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function Sec63 PF02889.16 KXZ47537.1 - 6.1e-22 78.0 0.0 9.1e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KXZ47537.1 - 7.5e-19 68.2 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ47537.1 - 6.9e-07 29.4 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXZ47537.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain HHH_2 PF12826.7 KXZ47537.1 - 0.15 12.2 1.7 1 9.5 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif Chalcone_2 PF16035.5 KXZ47538.1 - 2.3e-05 24.3 0.0 0.00027 20.8 0.0 2.4 2 1 0 2 2 2 1 Chalcone isomerase like Chalcone_3 PF16036.5 KXZ47538.1 - 0.00082 19.5 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase-like JmjC PF02373.22 KXZ47539.1 - 1.6e-05 25.3 0.6 3.3e-05 24.3 0.2 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Zn_ribbon_17 PF17120.5 KXZ47539.1 - 0.22 11.2 6.4 0.46 10.1 6.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_2 PF03107.16 KXZ47539.1 - 0.3 11.4 3.4 0.65 10.4 3.4 1.5 1 0 0 1 1 1 0 C1 domain WD40 PF00400.32 KXZ47540.1 - 3.7e-37 125.7 18.4 1e-09 38.8 0.6 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KXZ47540.1 - 0.0017 17.2 0.0 1.2 7.8 0.0 3.2 1 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KXZ47540.1 - 0.44 9.1 1.8 21 3.6 0.0 3.1 2 2 1 3 3 3 0 Nucleoporin Nup120/160 GYF PF02213.16 KXZ47541.1 - 0.0039 16.8 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 GYF domain YniB PF14002.6 KXZ47542.1 - 0.018 14.8 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 YniB-like protein DotU PF09850.9 KXZ47542.1 - 0.031 14.0 0.2 0.036 13.8 0.2 1.1 1 0 0 1 1 1 0 Type VI secretion system protein DotU HemY_N PF07219.13 KXZ47542.1 - 0.039 14.1 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Vezatin PF12632.7 KXZ47542.1 - 0.041 13.3 0.0 0.05 13.0 0.0 1.0 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Tom5 PF10642.9 KXZ47544.1 - 2.8 8.0 8.6 6.4 6.9 5.7 2.8 2 1 0 2 2 2 0 Mitochondrial import receptor subunit or translocase TFIIA PF03153.13 KXZ47545.1 - 3.4 7.6 11.8 5.2 7.0 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.18 KXZ47546.1 - 5.9e-10 38.1 5.4 9.9e-10 37.4 5.4 1.4 1 0 0 1 1 1 1 Membrane transport protein CRAL_TRIO PF00650.20 KXZ47547.1 - 1.4e-21 76.9 0.0 1.5e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CCDC85 PF10226.9 KXZ47548.1 - 0.0029 17.3 0.4 0.0046 16.7 0.4 1.2 1 0 0 1 1 1 1 CCDC85 family ATG16 PF08614.11 KXZ47548.1 - 0.015 15.5 0.7 0.015 15.5 0.7 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 KXZ47548.1 - 0.024 15.3 0.1 0.035 14.7 0.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KXZ47548.1 - 0.054 13.9 0.3 0.11 13.0 0.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB UPF0242 PF06785.11 KXZ47548.1 - 0.068 13.3 0.2 0.072 13.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KXZ47548.1 - 0.072 12.4 0.4 0.1 11.9 0.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Amino_oxidase PF01593.24 KXZ47550.1 - 2.8e-71 241.2 3.9 3.9e-71 240.7 3.9 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ47550.1 - 1.7e-16 60.2 0.4 1.7e-16 60.2 0.4 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ47550.1 - 2.9e-06 26.6 9.0 1.7e-05 24.1 9.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXZ47550.1 - 3.1e-06 27.7 0.5 2.9e-05 24.6 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ47550.1 - 6.4e-06 25.6 0.1 1.4e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXZ47550.1 - 7.1e-06 25.5 0.2 3.5e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ47550.1 - 8.2e-06 25.6 3.5 8.2e-06 25.6 3.5 2.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXZ47550.1 - 1.2e-05 24.2 0.2 2.4e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KXZ47550.1 - 5.6e-05 22.5 0.9 5.6e-05 22.5 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXZ47550.1 - 0.00068 19.0 2.7 0.0013 18.0 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXZ47550.1 - 0.00073 19.0 2.3 0.00073 19.0 2.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXZ47550.1 - 0.01 15.1 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXZ47550.1 - 0.03 13.4 0.2 0.051 12.6 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.6 KXZ47550.1 - 0.032 14.7 0.1 0.46 11.0 0.0 2.6 3 1 0 3 3 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 KXZ47550.1 - 0.051 12.6 0.3 0.051 12.6 0.3 1.8 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KXZ47550.1 - 0.093 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HlyE PF06109.13 KXZ47550.1 - 0.76 9.0 2.6 1.2 8.4 2.6 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) Kinesin PF00225.23 KXZ47551.1 - 4.2e-89 298.7 0.0 5.1e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ47551.1 - 2.4e-21 76.2 0.0 5.9e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding Kinesin_assoc PF16183.5 KXZ47551.1 - 9.1e-06 25.9 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Kinesin-associated Glyco_hydro_63 PF03200.16 KXZ47552.1 - 2.1e-07 30.1 0.2 0.00073 18.4 0.0 3.3 2 1 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Trehalase PF01204.18 KXZ47552.1 - 0.007 15.3 0.0 0.019 13.8 0.0 1.6 2 0 0 2 2 2 1 Trehalase Sec23_trunk PF04811.15 KXZ47553.1 - 9.9e-15 54.8 0.0 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 KXZ47553.1 - 0.0063 16.5 2.5 0.012 15.6 2.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Asp_protease PF09668.10 KXZ47554.1 - 2.4e-51 172.7 1.4 3.5e-51 172.2 1.4 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXZ47554.1 - 1.8e-17 63.7 0.4 3.7e-17 62.7 0.4 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.31 KXZ47554.1 - 1.2e-10 41.0 1.9 2e-10 40.4 0.7 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Asp_protease_2 PF13650.6 KXZ47554.1 - 4.7e-09 36.8 0.2 1e-08 35.7 0.2 1.6 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.6 KXZ47554.1 - 0.00042 20.1 0.2 0.0011 18.8 0.1 1.8 2 0 0 2 2 2 1 UBA-like domain RVP PF00077.20 KXZ47554.1 - 0.0041 17.4 0.0 0.015 15.6 0.1 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease YecM PF06185.12 KXZ47554.1 - 0.013 15.2 0.0 0.052 13.2 0.0 1.9 2 1 0 2 2 2 0 YecM protein MSA-2c PF12238.8 KXZ47554.1 - 2.4 8.1 9.1 7.1 6.6 9.1 1.8 1 0 0 1 1 1 0 Merozoite surface antigen 2c SPATA3 PF15662.5 KXZ47554.1 - 4 8.0 7.2 6.3 7.4 7.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family MAM33 PF02330.16 KXZ47555.1 - 3.1e-36 125.3 0.1 6.5e-36 124.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial glycoprotein Sulfate_transp PF00916.20 KXZ47557.1 - 2.5e-71 240.4 10.0 3.6e-71 239.9 10.0 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXZ47557.1 - 3.1e-16 59.1 0.0 5.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KXZ47557.1 - 1.9e-08 34.5 2.5 9.6e-08 32.3 1.1 3.1 2 0 0 2 2 2 1 STAS domain Rhodanese PF00581.20 KXZ47557.1 - 5.4e-05 23.7 0.0 0.00032 21.2 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain MFS_MOT1 PF16983.5 KXZ47557.1 - 0.0011 19.3 5.5 0.0011 19.3 5.5 4.6 4 1 1 5 5 5 1 Molybdate transporter of MFS superfamily SUR7 PF06687.12 KXZ47557.1 - 0.099 12.3 0.8 0.18 11.4 0.8 1.4 1 0 0 1 1 1 0 SUR7/PalI family PBP_like_2 PF12849.7 KXZ47558.1 - 6.5e-42 144.1 10.6 1.6e-20 73.9 0.3 3.5 3 0 0 3 3 3 3 PBP superfamily domain SBP_bac_6 PF13343.6 KXZ47558.1 - 0.012 15.0 0.0 2.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial extracellular solute-binding protein DUF4190 PF13828.6 KXZ47558.1 - 0.038 13.7 1.2 0.15 11.9 1.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) HNH PF01844.23 KXZ47559.1 - 0.00017 21.7 0.5 0.00038 20.6 0.5 1.6 1 1 0 1 1 1 1 HNH endonuclease OrsD PF12013.8 KXZ47559.1 - 0.053 14.0 0.1 0.097 13.1 0.1 1.4 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Acetyltransf_1 PF00583.25 KXZ47559.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DNA_pol_A_exo1 PF01612.20 KXZ47560.1 - 3.4e-13 49.7 0.0 1.5e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease tRNA_edit PF04073.15 KXZ47560.1 - 4.8e-11 42.8 0.5 5.1e-06 26.6 0.3 2.9 1 1 1 2 2 2 2 Aminoacyl-tRNA editing domain QueH PF02677.14 KXZ47560.1 - 0.011 15.8 0.4 0.011 15.8 0.4 2.1 2 0 0 2 2 2 0 Epoxyqueuosine reductase QueH tRNA_anti-codon PF01336.25 KXZ47560.1 - 0.11 12.4 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain mTERF PF02536.14 KXZ47561.1 - 0.00048 19.2 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 mTERF CitMHS PF03600.16 KXZ47562.1 - 2.4e-48 164.9 26.0 5e-42 144.1 6.0 2.3 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 KXZ47562.1 - 1.8e-36 123.8 3.6 1.4e-08 34.4 0.0 4.3 4 0 0 4 4 4 4 TrkA-C domain Na_sulph_symp PF00939.19 KXZ47562.1 - 2.9e-13 49.7 28.4 8.2e-08 31.7 13.9 2.7 2 1 1 3 3 3 3 Sodium:sulfate symporter transmembrane region HlyD_D23 PF16576.5 KXZ47562.1 - 0.069 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion MIS13 PF08202.11 KXZ47563.1 - 0.00054 19.3 0.2 0.00078 18.8 0.2 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DegS PF05384.11 KXZ47563.1 - 0.037 13.5 0.1 0.074 12.5 0.1 1.4 1 0 0 1 1 1 0 Sensor protein DegS OsmC PF02566.19 KXZ47563.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 OsmC-like protein MatE PF01554.18 KXZ47564.1 - 6.4e-54 181.9 18.9 6.3e-28 97.4 5.4 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ47564.1 - 8.2 6.5 29.1 0.43 10.6 7.1 4.1 3 1 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain Ion_trans PF00520.31 KXZ47565.1 - 6.9e-168 556.0 97.5 5.1e-48 163.4 20.1 5.2 5 0 0 5 5 5 5 Ion transport protein PKD_channel PF08016.12 KXZ47565.1 - 4.4e-12 45.4 78.4 1.3e-09 37.2 5.8 8.8 6 3 3 9 9 9 5 Polycystin cation channel GPHH PF16905.5 KXZ47565.1 - 7.1e-05 22.5 0.0 0.00029 20.5 0.0 2.2 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF3935 PF13071.6 KXZ47565.1 - 0.2 12.2 0.1 0.2 12.2 0.1 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3935) SNase PF00565.17 KXZ47566.1 - 0.037 14.5 0.5 7.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Staphylococcal nuclease homologue Mod_r PF07200.13 KXZ47566.1 - 0.36 10.9 4.0 0.9 9.6 0.3 2.4 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KXZ47566.1 - 0.92 8.3 5.8 0.31 9.9 2.9 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Mobilization_B PF17511.2 KXZ47566.1 - 1.3 9.4 7.7 0.6 10.5 2.3 2.2 2 0 0 2 2 2 0 Mobilization protein B APG6_N PF17675.1 KXZ47566.1 - 3.7 8.1 7.1 1.6 9.3 0.4 2.5 2 1 1 3 3 3 0 Apg6 coiled-coil region PAN_4 PF14295.6 KXZ47567.1 - 0.0011 18.9 12.8 0.014 15.3 12.8 2.6 1 1 0 1 1 1 1 PAN domain Alpha-amylase_C PF02806.18 KXZ47568.1 - 1.7e-22 79.7 0.1 4.3e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KXZ47568.1 - 7.4e-12 45.5 1.2 1.3e-10 41.4 0.1 2.2 1 1 1 2 2 2 1 Alpha amylase, catalytic domain CBM_48 PF02922.18 KXZ47568.1 - 9.2e-12 45.2 0.3 2.5e-11 43.8 0.3 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.6 KXZ47568.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain PapB PF03333.13 KXZ47570.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein BTB PF00651.31 KXZ47571.1 - 5e-05 23.5 0.0 0.00015 21.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Peptidase_S49 PF01343.18 KXZ47573.1 - 4.8e-26 91.6 0.1 7.1e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S49 Rhodanese PF00581.20 KXZ47574.1 - 2e-12 47.6 0.0 2.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain TMF_DNA_bd PF12329.8 KXZ47575.1 - 0.00014 21.7 6.8 0.00014 21.7 6.8 7.2 5 2 2 7 7 7 2 TATA element modulatory factor 1 DNA binding SUIM_assoc PF16619.5 KXZ47575.1 - 0.004 17.2 2.0 0.045 13.8 2.0 2.9 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 HEAT PF02985.22 KXZ47576.1 - 2.6e-05 24.1 1.3 4.7 7.7 0.0 4.1 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 KXZ47576.1 - 0.036 14.6 3.9 0.47 11.0 0.2 3.6 3 0 0 3 3 3 0 HEAT-like repeat RTP1_C1 PF10363.9 KXZ47576.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KXZ47576.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CLASP N terminal PP2C PF00481.21 KXZ47577.1 - 5.9e-38 131.0 0.0 8e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C cNMP_binding PF00027.29 KXZ47577.1 - 1.1e-16 60.7 0.0 7.4e-16 58.0 0.0 2.4 1 1 1 2 2 2 1 Cyclic nucleotide-binding domain PP2C_2 PF13672.6 KXZ47577.1 - 0.00023 20.9 0.3 0.0032 17.2 0.3 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C Polyketide_cyc PF03364.20 KXZ47578.1 - 1.2e-08 35.2 0.0 3.3e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KXZ47578.1 - 6.4e-07 29.7 0.1 8.5e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF220 PF02713.14 KXZ47578.1 - 0.00091 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF220 CitMHS PF03600.16 KXZ47579.1 - 6.5e-41 140.5 27.0 3.4e-40 138.1 13.4 2.4 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 KXZ47579.1 - 4.1e-37 125.9 2.0 6.1e-09 35.6 0.0 4.4 4 0 0 4 4 4 4 TrkA-C domain Na_sulph_symp PF00939.19 KXZ47579.1 - 6.7e-14 51.8 25.5 2.3e-08 33.5 12.9 2.4 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region HlyD_D23 PF16576.5 KXZ47579.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion VirB3 PF05101.13 KXZ47579.1 - 4.4 7.6 9.0 11 6.4 0.0 3.7 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein US2 PF02476.15 KXZ47580.1 - 0.0014 19.3 0.3 0.0022 18.7 0.3 1.4 1 1 0 1 1 1 1 US2 family AAA_22 PF13401.6 KXZ47581.1 - 1.3e-08 35.2 0.0 4e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 KXZ47581.1 - 3.5e-06 27.1 0.0 2.7e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Torsin AAA_16 PF13191.6 KXZ47581.1 - 6.3e-05 23.4 0.5 0.23 11.8 0.0 3.1 3 1 1 4 4 4 2 AAA ATPase domain AAA_30 PF13604.6 KXZ47581.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ47581.1 - 0.016 15.7 0.0 0.03 14.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ47581.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KXZ47581.1 - 0.19 12.1 0.0 6.4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mpv17_PMP22 PF04117.12 KXZ47582.1 - 8e-17 61.2 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_M16 PF00675.20 KXZ47583.1 - 6.2e-17 62.0 0.0 4.4e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) SNF2_N PF00176.23 KXZ47584.1 - 2.8e-34 118.4 0.0 6.6e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ47584.1 - 3.1e-18 66.1 0.0 6.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2722 PF10846.8 KXZ47584.1 - 0.055 12.4 4.1 0.057 12.4 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ResIII PF04851.15 KXZ47584.1 - 0.081 12.9 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit BAF1_ABF1 PF04684.13 KXZ47584.1 - 0.16 11.0 2.6 0.25 10.3 2.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.8 KXZ47584.1 - 2.9 7.5 18.6 7.5 6.1 0.2 2.2 2 0 0 2 2 2 0 Spt20 family PepSY_2 PF13670.6 KXZ47584.1 - 7.8 6.6 8.4 30 4.7 8.4 2.0 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Formyl_trans_C PF02911.18 KXZ47585.1 - 6e-16 58.5 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF1889 PF08986.10 KXZ47585.1 - 0.006 17.0 1.2 4.5 7.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1889) Band_7 PF01145.25 KXZ47586.1 - 1.9e-25 89.9 6.1 3.2e-25 89.2 6.1 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 KXZ47586.1 - 0.076 13.2 0.9 0.13 12.4 0.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 tRNA-synt_1g PF09334.11 KXZ47587.1 - 1.9e-61 207.9 0.1 1.4e-39 136.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA_bind PF01588.20 KXZ47587.1 - 1.2e-27 95.8 0.1 2.9e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 KXZ47587.1 - 0.0004 18.8 0.0 0.00076 17.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DUF4357 PF14267.6 KXZ47587.1 - 0.39 10.7 1.8 0.62 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) peroxidase PF00141.23 KXZ47588.1 - 6.6e-50 169.9 0.0 8.5e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase RNase_P_p30 PF01876.16 KXZ47591.1 - 6.9e-46 156.4 0.8 9.3e-46 156.0 0.8 1.2 1 0 0 1 1 1 1 RNase P subunit p30 DUF1116 PF06545.11 KXZ47593.1 - 1.6e-31 109.5 0.5 3.9e-13 49.4 0.0 4.2 3 1 0 3 3 3 3 Protein of unknown function (DUF1116) Thioredoxin PF00085.20 KXZ47594.1 - 2.8e-57 191.1 1.9 1.1e-30 105.6 0.1 3.9 3 1 2 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 KXZ47594.1 - 5.6e-31 107.9 0.6 3.5e-23 82.5 1.1 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KXZ47594.1 - 2.9e-09 37.4 0.9 0.00097 19.6 0.0 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXZ47594.1 - 3.9e-09 36.3 0.0 0.02 14.3 0.0 3.4 3 1 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KXZ47594.1 - 9.8e-09 35.3 0.0 0.017 15.3 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KXZ47594.1 - 2.6e-07 30.9 0.1 0.087 13.2 0.0 4.5 4 1 1 5 5 4 2 Thioredoxin-like AhpC-TSA PF00578.21 KXZ47594.1 - 1e-05 25.4 0.6 0.35 10.8 0.0 3.5 2 2 2 5 5 5 2 AhpC/TSA family ERp29_N PF07912.13 KXZ47594.1 - 1.4e-05 25.3 0.1 0.099 12.8 0.0 3.1 3 0 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 KXZ47594.1 - 0.00062 19.8 0.1 0.32 11.1 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin domain Redoxin PF08534.10 KXZ47594.1 - 0.0007 19.3 5.9 0.72 9.6 0.1 3.6 3 1 1 4 4 4 2 Redoxin HyaE PF07449.11 KXZ47594.1 - 0.002 18.1 0.1 1.2 9.1 0.0 3.9 3 2 1 4 4 4 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KXZ47594.1 - 0.0049 16.7 0.0 0.66 9.8 0.0 2.7 3 0 0 3 3 3 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 KXZ47594.1 - 0.013 15.7 1.9 0.46 10.7 0.0 2.7 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin_9 PF14595.6 KXZ47594.1 - 0.15 11.8 0.2 4.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin PXA PF02194.15 KXZ47595.1 - 9.6e-17 61.5 0.0 1.9e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 PXA domain PX PF00787.24 KXZ47595.1 - 2.2e-12 46.9 0.0 3.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 PX domain Nexin_C PF08628.12 KXZ47595.1 - 4.1e-11 43.5 0.0 8.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Sorting nexin C terminal Acyl_transf_1 PF00698.21 KXZ47596.1 - 4.5e-25 88.8 0.4 4.4e-24 85.6 0.4 2.0 1 1 0 1 1 1 1 Acyl transferase domain Ank_5 PF13857.6 KXZ47596.1 - 2.8e-08 33.9 0.1 3.4e-07 30.4 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ47596.1 - 4.3e-08 33.3 1.1 0.001 19.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXZ47596.1 - 1.3e-07 32.0 0.3 1.4e-05 25.6 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47596.1 - 1.4e-07 32.0 0.0 6.3e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47596.1 - 2e-06 27.7 0.5 0.14 12.8 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Tcf25 PF04910.14 KXZ47596.1 - 0.077 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 STI1 PF17830.1 KXZ47596.1 - 0.08 12.9 0.6 11 6.0 0.0 2.8 2 0 0 2 2 2 0 STI1 domain DUF4156 PF13698.6 KXZ47597.1 - 0.083 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) SET PF00856.28 KXZ47598.1 - 1.5e-05 25.5 0.0 0.24 11.8 0.0 2.4 1 1 0 2 2 2 2 SET domain 2OG-FeII_Oxy_3 PF13640.6 KXZ47601.1 - 1.1e-17 64.7 0.0 2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ47601.1 - 8.6e-07 29.4 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nore1-SARAH PF16517.5 KXZ47601.1 - 0.082 12.8 0.7 3.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Myb_DNA-binding PF00249.31 KXZ47602.1 - 3.3e-12 46.4 0.0 5.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ47602.1 - 0.00036 20.7 0.0 0.00066 19.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SAD_SRA PF02182.17 KXZ47603.1 - 1.9e-22 79.6 0.0 3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain SET PF00856.28 KXZ47603.1 - 6.7e-12 46.1 0.0 1.4e-10 41.8 0.0 2.8 2 1 0 2 2 2 1 SET domain PfkB PF00294.24 KXZ47604.1 - 4e-17 62.5 0.2 7.5e-16 58.3 0.2 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.24 KXZ47605.1 - 1.6e-08 34.2 0.2 2.2e-06 27.2 0.2 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Trypsin_2 PF13365.6 KXZ47606.1 - 1.8e-26 93.8 4.8 6.3e-24 85.6 4.8 2.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KXZ47606.1 - 3.2e-16 59.4 0.0 7.1e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 KXZ47606.1 - 6.5e-12 45.7 0.2 1.8e-08 34.5 0.2 2.2 2 0 0 2 2 2 2 Trypsin PDZ_6 PF17820.1 KXZ47606.1 - 4.3e-05 23.3 2.0 0.036 13.9 0.1 3.0 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 KXZ47606.1 - 0.0027 17.6 0.2 0.056 13.4 0.0 2.5 2 0 0 2 2 2 1 Tricorn protease PDZ domain PDZ PF00595.24 KXZ47606.1 - 0.049 14.0 3.1 0.1 13.0 0.2 3.0 3 1 0 3 3 3 0 PDZ domain Peptidase_S46 PF10459.9 KXZ47606.1 - 0.6 8.7 1.3 1.1 7.9 1.3 1.3 1 0 0 1 1 1 0 Peptidase S46 WD40 PF00400.32 KXZ47607.1 - 2.6e-110 357.2 29.5 3.1e-10 40.5 0.1 14.7 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ47607.1 - 1.9e-33 114.6 0.0 0.00023 21.4 0.0 9.8 5 2 5 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ47607.1 - 7.1e-13 48.2 3.3 0.081 11.9 0.0 7.6 4 2 4 9 9 9 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXZ47607.1 - 2.2e-10 40.2 0.0 4.3 7.4 0.0 8.8 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KXZ47607.1 - 0.00084 18.0 2.3 0.0082 14.7 0.2 3.1 3 1 1 4 4 4 1 Cytochrome D1 heme domain Nup160 PF11715.8 KXZ47607.1 - 0.0055 15.4 3.6 1.4 7.5 0.1 5.0 6 1 1 7 7 7 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXZ47607.1 - 0.14 11.5 0.4 64 2.7 0.0 4.1 3 2 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal HET PF06985.11 KXZ47607.1 - 1.8 8.9 3.8 0.78 10.1 0.0 2.1 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) NHL PF01436.21 KXZ47607.1 - 2.1 8.5 4.4 17 5.7 0.0 4.4 4 0 0 4 4 4 0 NHL repeat Metallophos PF00149.28 KXZ47608.1 - 1.5e-07 32.1 4.1 7.7e-07 29.8 4.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_S9 PF00326.21 KXZ47609.1 - 1.9e-41 141.9 0.0 5.6e-41 140.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KXZ47609.1 - 9.8e-23 80.6 0.0 6.2e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Aminotran_3 PF00202.21 KXZ47610.1 - 1.4e-63 214.9 0.0 1.2e-54 185.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-III DEC-1_N PF04625.13 KXZ47610.1 - 3.7 6.5 11.6 5.6 5.9 11.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.25 KXZ47611.1 - 1.7e-19 70.2 0.0 9.6e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47611.1 - 2.8e-16 59.6 0.0 1.2e-14 54.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ47611.1 - 0.18 11.7 5.2 0.6 10.0 5.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family WBS_methylT PF12589.8 KXZ47612.1 - 3e-20 72.7 6.6 4.9e-20 72.1 6.6 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KXZ47612.1 - 1.4e-11 44.9 0.1 4.6e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ47612.1 - 5.3e-10 39.9 0.0 1.3e-09 38.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ47612.1 - 0.00011 22.9 0.0 0.00038 21.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ47612.1 - 0.0036 17.2 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ47612.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NUFIP1 PF10453.9 KXZ47613.1 - 6.3e-08 32.3 1.1 6.3e-08 32.3 1.1 2.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) SBP PF03110.14 KXZ47614.1 - 6.2e-27 93.7 8.4 1.1e-26 93.0 8.4 1.4 1 0 0 1 1 1 1 SBP domain BTB PF00651.31 KXZ47614.1 - 9.1e-14 51.6 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Vps54_N PF10475.9 KXZ47615.1 - 4.1e-53 180.5 0.1 5.8e-53 180.1 0.1 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXZ47615.1 - 1.4e-40 139.6 0.0 6e-40 137.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) COG5 PF10392.9 KXZ47615.1 - 0.00031 20.9 3.0 0.0064 16.7 0.0 3.2 2 1 1 3 3 3 1 Golgi transport complex subunit 5 COG2 PF06148.11 KXZ47615.1 - 0.16 12.1 2.3 1.2 9.2 2.3 2.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1296 PF06972.11 KXZ47616.1 - 4.4e-11 42.7 0.1 6.9e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) UBA_4 PF14555.6 KXZ47616.1 - 0.004 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Pkinase PF00069.25 KXZ47617.1 - 8.5e-56 189.2 0.0 1.2e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47617.1 - 1.9e-40 138.8 0.0 2.9e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ47617.1 - 0.0001 21.2 0.1 0.00026 19.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXZ47617.1 - 0.00023 20.6 0.8 0.0005 19.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PBP1_TM PF14812.6 KXZ47617.1 - 0.0063 16.9 2.7 0.0063 16.9 2.7 2.5 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Kdo PF06293.14 KXZ47617.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXZ47617.1 - 0.085 11.8 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Cpn60_TCP1 PF00118.24 KXZ47618.1 - 9.9e-165 548.9 0.2 1.2e-164 548.5 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family U-box PF04564.15 KXZ47619.1 - 4.6e-11 42.7 0.0 8.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain Phycobilisome PF00502.19 KXZ47619.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome protein Pkinase_Tyr PF07714.17 KXZ47620.1 - 8.1e-15 54.8 0.0 1.6e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ47620.1 - 5.7e-09 35.7 0.0 6.9e-08 32.2 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain TUG-UBL1 PF11470.8 KXZ47621.1 - 1.3e-13 51.0 0.0 2.1e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KXZ47621.1 - 0.22 11.8 0.0 0.45 10.8 0.0 1.4 1 0 0 1 1 1 0 UBX domain 2-Hacid_dh_C PF02826.19 KXZ47624.1 - 4e-45 153.3 0.0 6.7e-45 152.6 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXZ47624.1 - 4.3e-07 30.2 0.0 7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KXZ47624.1 - 0.00025 20.7 0.0 0.0092 15.6 0.0 2.2 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KXZ47624.1 - 0.00046 20.7 0.1 0.0016 19.0 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXZ47624.1 - 0.0022 17.9 1.3 0.0037 17.2 1.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KXZ47624.1 - 0.0067 16.1 1.5 0.011 15.3 1.5 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KXZ47624.1 - 0.024 14.6 0.2 0.12 12.3 0.3 2.0 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 KXZ47624.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 KXZ47624.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PSI_integrin PF17205.3 KXZ47625.1 - 0.093 12.5 13.5 0.98 9.2 2.3 2.5 2 0 0 2 2 2 0 Integrin plexin domain PSI PF01437.25 KXZ47625.1 - 0.48 11.0 10.3 0.25 11.9 1.1 2.4 2 0 0 2 2 2 0 Plexin repeat Enterotoxin_HS1 PF08090.11 KXZ47625.1 - 0.67 10.0 10.3 0.96 9.5 5.7 2.6 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Vps54 PF07928.12 KXZ47631.1 - 1.5e-27 96.6 0.0 1e-26 93.9 0.0 2.2 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KXZ47631.1 - 3.3e-08 33.2 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Seryl_tRNA_N PF02403.22 KXZ47631.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Radical_SAM PF04055.21 KXZ47632.1 - 1.5e-12 48.2 0.0 3.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KXZ47632.1 - 0.00013 22.1 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KXZ47632.1 - 0.0093 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain PGA_cap PF09587.10 KXZ47632.1 - 0.034 13.6 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap His_Phos_1 PF00300.22 KXZ47633.1 - 7e-13 48.7 0.5 1.2e-12 47.9 0.5 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Conotoxin PF02950.17 KXZ47634.1 - 8.5 7.5 6.6 77 4.4 2.6 3.3 3 0 0 3 3 3 0 Conotoxin SnoaL PF07366.12 KXZ47636.1 - 1.5e-08 34.5 0.1 5e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXZ47636.1 - 2e-07 31.6 4.5 2.5e-07 31.3 0.3 3.0 3 1 0 3 3 3 1 SnoaL-like domain SMC_N PF02463.19 KXZ47637.1 - 2.7e-35 121.8 1.0 3.9e-35 121.3 1.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXZ47637.1 - 5.4e-17 62.9 1.4 5.4e-17 62.9 1.4 1.6 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 KXZ47637.1 - 7.2e-09 35.8 0.1 2e-08 34.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KXZ47637.1 - 4.2e-05 23.5 0.1 6.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ47637.1 - 0.00012 21.7 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KXZ47637.1 - 0.17 12.4 2.0 0.41 11.2 2.0 2.1 1 1 0 1 1 1 0 ABC transporter DUF349 PF03993.12 KXZ47637.1 - 0.6 10.4 11.0 0.071 13.4 1.8 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) SMC_N PF02463.19 KXZ47638.1 - 2.3e-29 102.4 0.1 3.2e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXZ47638.1 - 3.2e-23 82.3 0.0 9.8e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXZ47638.1 - 0.00029 20.8 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 KXZ47638.1 - 0.0031 16.4 64.1 0.031 13.1 11.6 5.1 3 1 2 5 5 5 4 Spc7 kinetochore protein ABC_tran PF00005.27 KXZ47638.1 - 0.0082 16.7 0.0 0.06 13.9 0.0 2.8 1 1 0 1 1 1 1 ABC transporter DUF16 PF01519.16 KXZ47638.1 - 0.19 12.2 24.5 0.92 10.0 1.7 5.3 5 1 0 5 5 5 0 Protein of unknown function DUF16 GAS PF13851.6 KXZ47638.1 - 0.24 10.7 60.1 0.15 11.4 1.7 5.9 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KXZ47638.1 - 2.4 6.7 50.0 0.016 13.9 19.0 3.8 3 1 1 4 4 4 0 AAA domain BLOC1_2 PF10046.9 KXZ47638.1 - 2.8 8.3 28.9 0.41 11.0 3.0 5.2 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KXZ47638.1 - 4.4 7.7 54.9 1.5 9.2 2.0 4.6 2 1 2 4 4 4 0 Fez1 Nup96 PF12110.8 KXZ47639.1 - 4.4e-51 173.7 0.3 6.6e-51 173.2 0.3 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KXZ47639.1 - 2.2e-37 128.5 0.0 3e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KXZ47639.1 - 0.00011 22.9 25.4 0.00011 22.9 25.4 10.3 3 3 5 8 8 8 3 Nucleoporin FG repeat region NUDE_C PF04880.13 KXZ47640.1 - 0.0016 18.9 4.2 0.0023 18.5 4.2 1.3 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region G0-G1_switch_2 PF15103.6 KXZ47640.1 - 0.042 14.3 0.3 0.072 13.5 0.3 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 FAP PF07174.11 KXZ47640.1 - 0.12 11.8 29.7 0.19 11.1 29.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) EMC3_TMCO1 PF01956.16 KXZ47640.1 - 0.14 11.9 0.4 0.19 11.4 0.4 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SARG PF15385.6 KXZ47640.1 - 0.54 9.4 16.4 0.7 9.1 16.4 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein RPA43_OB PF17875.1 KXZ47641.1 - 0.021 15.4 0.0 0.021 15.4 0.0 5.1 3 2 1 4 4 4 0 RPA43 OB domain in RNA Pol I COG7 PF10191.9 KXZ47642.1 - 2.7e-96 323.5 0.0 5e-96 322.7 0.0 1.4 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) COG2 PF06148.11 KXZ47642.1 - 0.027 14.5 2.0 0.31 11.1 1.3 2.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KXZ47642.1 - 0.062 13.5 0.0 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Pkip-1 PF06878.11 KXZ47642.1 - 0.11 12.7 0.3 0.28 11.3 0.2 1.7 2 0 0 2 2 2 0 Pkip-1 protein EFTUD2 PF16004.5 KXZ47643.1 - 0.95 10.1 4.4 1.9 9.1 4.4 1.4 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Baculo_RING PF05883.11 KXZ47644.1 - 0.024 14.6 0.2 0.032 14.2 0.2 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain SDA1 PF05285.12 KXZ47645.1 - 0.014 14.8 1.0 0.02 14.3 1.0 1.1 1 0 0 1 1 1 0 SDA1 F-box PF00646.33 KXZ47645.1 - 0.015 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain Roughex PF06020.11 KXZ47645.1 - 7.7 5.5 8.5 12 4.9 8.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PseudoU_synth_1 PF01416.20 KXZ47646.1 - 1.4e-28 99.5 0.0 2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase DUF3223 PF11523.8 KXZ47647.1 - 9.1e-18 64.9 0.0 9.9e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) TrmB PF01978.19 KXZ47647.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Inositol_P PF00459.25 KXZ47648.1 - 6.3e-56 189.9 0.2 9.8e-56 189.2 0.2 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family RPAP3_C PF13877.6 KXZ47649.1 - 2.5e-17 63.2 0.0 4.6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KXZ47649.1 - 3e-16 58.5 4.1 2.1e-06 27.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ47649.1 - 1.5e-15 56.0 7.1 4.4e-06 26.4 0.0 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ47649.1 - 2.6e-08 33.4 3.4 0.0058 16.3 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 KXZ47649.1 - 7.8e-05 22.9 8.2 0.00047 20.4 0.2 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ47649.1 - 0.00022 21.2 1.2 0.5 10.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ47649.1 - 0.018 15.8 0.0 0.018 15.8 0.0 5.9 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ47649.1 - 0.2 12.1 3.3 1.2 9.7 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Bac_rhodopsin PF01036.18 KXZ47650.1 - 7.7e-14 51.8 8.2 1.2e-13 51.1 8.2 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein G-patch PF01585.23 KXZ47651.1 - 4.3e-12 45.7 0.1 4.3e-12 45.7 0.1 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXZ47651.1 - 0.0033 17.5 0.3 0.0033 17.5 0.3 3.1 2 1 1 3 3 3 1 G-patch domain Bac_rhodopsin PF01036.18 KXZ47652.1 - 4.1e-16 59.2 14.4 7.4e-16 58.4 14.4 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Senescence_reg PF04520.13 KXZ47655.1 - 0.058 14.2 0.3 0.11 13.3 0.3 1.6 1 1 0 1 1 1 0 Senescence regulator Coprogen_oxidas PF01218.18 KXZ47656.1 - 3.3e-130 433.1 0.1 1.9e-129 430.6 0.1 1.8 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase CBM_48 PF02922.18 KXZ47657.1 - 4.9e-09 36.4 0.0 1.3e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KXZ47657.1 - 0.00029 20.5 0.0 0.033 13.7 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain TauE PF01925.19 KXZ47658.1 - 5.5e-35 121.1 51.9 1.4e-19 70.7 23.8 2.3 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE Tub PF01167.18 KXZ47659.1 - 3.7e-29 102.2 0.0 2.5e-28 99.5 0.0 2.0 1 1 0 1 1 1 1 Tub family DUF3527 PF12043.8 KXZ47659.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Lipase_3 PF01764.25 KXZ47660.1 - 1.7e-05 24.7 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) CM_2 PF01817.21 KXZ47661.1 - 0.018 15.4 0.1 6.7 7.1 0.2 2.7 2 1 0 2 2 2 0 Chorismate mutase type II Pkinase PF00069.25 KXZ47662.1 - 2e-27 96.2 0.0 7.9e-15 54.9 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47662.1 - 1.4e-22 80.3 0.0 1.2e-11 44.4 0.0 3.4 4 0 0 4 4 4 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ47663.1 - 2.3e-27 96.0 0.0 2.9e-25 89.2 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47663.1 - 5.9e-22 78.2 0.0 4.3e-10 39.3 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ47663.1 - 0.03 14.2 3.4 0.12 12.3 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3138 PF11336.8 KXZ47663.1 - 0.031 12.9 1.2 0.064 11.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) LigT_PEase PF02834.16 KXZ47664.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 LigT like Phosphoesterase T3SS_needle_E PF08988.10 KXZ47664.1 - 0.14 12.3 1.2 0.44 10.7 0.7 2.1 1 1 1 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Pkinase PF00069.25 KXZ47665.1 - 4.7e-29 101.6 0.0 7.1e-28 97.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47665.1 - 4.7e-22 78.5 0.0 7.3e-12 45.1 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KXZ47665.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.9 4 0 0 4 4 4 0 Phosphotransferase enzyme family GntR PF00392.21 KXZ47667.1 - 0.076 12.7 0.1 0.28 10.9 0.0 2.0 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family Ysc84 PF04366.12 KXZ47669.1 - 1.9e-18 66.4 0.2 3.2e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator WD40_alt PF14077.6 KXZ47670.1 - 0.0019 18.1 0.3 0.0034 17.2 0.3 1.5 1 0 0 1 1 1 1 Alternative WD40 repeat motif DUF5344 PF17279.2 KXZ47670.1 - 0.019 15.5 9.6 0.094 13.3 2.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Spc7 PF08317.11 KXZ47670.1 - 0.077 11.9 23.7 0.09 11.6 23.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TACC_C PF05010.14 KXZ47670.1 - 0.15 11.9 23.7 0.055 13.2 18.1 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF16 PF01519.16 KXZ47670.1 - 0.16 12.5 17.2 0.054 14.0 11.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 PilJ PF13675.6 KXZ47670.1 - 0.19 11.8 11.5 0.15 12.1 6.0 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AATF-Che1 PF13339.6 KXZ47670.1 - 0.23 12.2 12.8 0.55 10.9 12.8 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Lebercilin PF15619.6 KXZ47670.1 - 0.32 10.6 28.0 0.42 10.2 28.0 1.0 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease XLF PF09302.11 KXZ47670.1 - 0.45 10.7 6.7 0.77 9.9 4.5 2.2 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF4407 PF14362.6 KXZ47670.1 - 1 8.7 13.8 1.4 8.2 13.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KXZ47670.1 - 1.1 9.1 22.4 0.059 13.2 13.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prominin PF05478.11 KXZ47670.1 - 1.4 6.8 8.3 1.6 6.6 8.3 1.1 1 0 0 1 1 1 0 Prominin MRP-S26 PF14943.6 KXZ47670.1 - 1.7 8.5 22.7 3.8 7.4 22.7 1.5 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF3450 PF11932.8 KXZ47670.1 - 1.7 7.9 20.4 4.6 6.5 20.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KXZ47670.1 - 2 8.9 27.0 6 7.4 26.9 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region STAT_alpha PF01017.20 KXZ47670.1 - 2.4 8.0 21.9 0.54 10.1 13.1 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain Atg14 PF10186.9 KXZ47670.1 - 2.5 7.1 17.9 2.9 6.9 17.9 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KIP1 PF07765.12 KXZ47670.1 - 3.9 7.6 11.8 10 6.3 8.0 3.1 1 1 1 2 2 2 0 KIP1-like protein FapA PF03961.13 KXZ47670.1 - 4.3 5.8 14.6 6.3 5.3 14.6 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A AAA_11 PF13086.6 KXZ47670.1 - 5 6.8 10.9 6.9 6.4 10.9 1.3 1 0 0 1 1 1 0 AAA domain Baculo_p24 PF05073.12 KXZ47670.1 - 5.9 6.6 9.7 2.7 7.7 5.2 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF3304 PF11745.8 KXZ47670.1 - 6.4 7.2 6.0 34 4.9 6.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) DUF1664 PF07889.12 KXZ47670.1 - 7 6.7 13.4 4.6 7.3 9.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KXZ47670.1 - 8.7 6.5 15.6 5.6 7.1 10.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 KXZ47670.1 - 9 6.6 29.8 0.15 12.4 19.3 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF3707 PF12499.8 KXZ47672.1 - 3e-17 63.5 3.5 3.5e-17 63.3 3.5 1.0 1 0 0 1 1 1 1 Pherophorin Lectin_C PF00059.21 KXZ47673.1 - 6.6e-07 30.0 0.0 9.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain mTERF PF02536.14 KXZ47674.1 - 0.066 12.1 0.0 0.43 9.5 0.0 1.8 1 1 1 2 2 2 0 mTERF eIF-1a PF01176.19 KXZ47675.1 - 3.1e-12 46.1 0.0 4.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 zf-MYND PF01753.18 KXZ47676.1 - 5.5e-07 29.6 9.4 1.2e-06 28.5 9.4 1.5 1 0 0 1 1 1 1 MYND finger SART-1 PF03343.13 KXZ47678.1 - 1.7e-66 225.1 18.3 5.9e-56 190.3 30.0 2.2 2 1 0 2 2 2 2 SART-1 family CCDC53 PF10152.9 KXZ47678.1 - 1 9.8 6.5 1 9.8 4.8 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Trm5_N PF18093.1 KXZ47678.1 - 1.4 8.9 3.4 8.1 6.4 0.1 3.0 3 0 0 3 3 3 0 tRNA methyltransferase 5 N-terminal domain RRF PF01765.19 KXZ47679.1 - 2.6e-60 203.1 1.4 2.6e-60 203.1 1.4 1.6 2 0 0 2 2 2 1 Ribosome recycling factor RRM_1 PF00076.22 KXZ47681.1 - 1.5e-17 63.2 0.1 3.2e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ47681.1 - 7.9e-06 25.5 0.0 9.8e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ47681.1 - 0.056 13.6 0.1 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif CPSase_L_D2 PF02786.17 KXZ47682.1 - 5.7e-84 280.8 0.1 1e-83 280.0 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXZ47682.1 - 1.1e-39 134.9 0.0 2.1e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXZ47682.1 - 4e-32 111.0 0.6 7.7e-22 77.9 0.0 2.8 1 1 1 2 2 2 2 Biotin carboxylase, N-terminal domain ATP-grasp PF02222.22 KXZ47682.1 - 4.5e-09 36.1 0.0 8.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXZ47682.1 - 9.7e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 KXZ47682.1 - 2.4e-05 24.0 0.0 9.2e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.6 KXZ47682.1 - 0.00068 19.4 0.0 0.0042 16.8 0.0 2.3 3 1 1 4 4 4 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KXZ47682.1 - 0.011 15.7 0.0 0.043 13.9 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 KXZ47682.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DRTGG PF07085.12 KXZ47682.1 - 0.081 12.7 0.0 4.4 7.1 0.1 2.4 2 0 0 2 2 2 0 DRTGG domain GARS_A PF01071.19 KXZ47682.1 - 0.13 12.0 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_C PF07478.13 KXZ47683.1 - 4.4e-16 59.0 0.0 1e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus SET PF00856.28 KXZ47683.1 - 4.7e-05 23.8 0.1 0.11 12.9 0.0 2.5 1 1 1 2 2 2 2 SET domain ATP-grasp_4 PF13535.6 KXZ47683.1 - 0.0025 17.4 0.3 0.24 11.0 0.0 3.4 4 0 0 4 4 4 1 ATP-grasp domain Sulfotransfer_2 PF03567.14 KXZ47683.1 - 0.018 15.0 0.0 0.25 11.2 0.0 2.4 2 1 0 2 2 2 0 Sulfotransferase family PAP_fibrillin PF04755.12 KXZ47684.1 - 4.8e-16 59.3 0.1 4.7e-07 29.9 0.0 3.0 2 1 0 2 2 2 2 PAP_fibrillin AhpC-TSA_2 PF13911.6 KXZ47685.1 - 3.8e-11 43.1 0.0 1e-10 41.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Tubulin PF00091.25 KXZ47687.1 - 2.9e-38 132.0 0.0 4.5e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KXZ47687.1 - 9.6e-27 93.1 0.8 5.9e-26 90.6 0.0 2.6 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 KXZ47687.1 - 0.015 14.5 1.9 0.028 13.6 1.9 1.4 1 1 0 1 1 1 0 Tubulin like HHA PF05321.11 KXZ47688.1 - 0.74 10.2 2.1 1.5 9.2 0.0 2.4 3 0 0 3 3 3 0 Haemolysin expression modulating protein CPSF_A PF03178.15 KXZ47691.1 - 0.032 13.5 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region BACK PF07707.15 KXZ47694.1 - 3.6e-07 30.2 0.0 5.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF3235 PF11574.8 KXZ47695.1 - 0.073 13.9 0.0 0.14 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) DUF155 PF02582.14 KXZ47696.1 - 9e-28 97.5 0.0 1.3e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 F-box PF00646.33 KXZ47697.1 - 4.2e-05 23.3 1.1 8.9e-05 22.3 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KXZ47697.1 - 9.1e-05 22.3 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 F-box LRR_4 PF12799.7 KXZ47697.1 - 0.00052 20.3 3.6 5.7 7.5 0.3 5.0 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ47697.1 - 0.035 13.9 10.1 0.051 13.3 0.2 3.6 4 0 0 4 4 4 0 Leucine rich repeat Pkinase PF00069.25 KXZ47698.1 - 0.037 13.4 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain fn3 PF00041.21 KXZ47699.1 - 6.8e-08 32.8 0.1 1.6e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KXZ47699.1 - 0.043 14.4 0.1 0.13 12.9 0.1 1.7 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain bZIP_1 PF00170.21 KXZ47700.1 - 3.4e-05 23.8 13.6 5.6e-05 23.1 10.4 2.8 1 1 2 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ47700.1 - 0.00052 20.0 15.9 0.0013 18.7 9.7 3.4 2 1 0 2 2 2 1 Basic region leucine zipper Dishevelled PF02377.15 KXZ47700.1 - 0.0012 19.3 5.0 0.0024 18.4 5.0 1.4 1 0 0 1 1 1 1 Dishevelled specific domain Rab5-bind PF09311.11 KXZ47700.1 - 0.054 12.9 9.1 0.08 12.3 9.1 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Golgin_A5 PF09787.9 KXZ47700.1 - 0.18 11.3 9.9 0.26 10.7 9.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 COG2 PF06148.11 KXZ47700.1 - 0.34 11.0 7.0 0.21 11.7 2.9 2.5 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KXZ47700.1 - 0.67 10.5 2.8 4 8.0 2.8 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein NAM-associated PF14303.6 KXZ47700.1 - 2.7 8.7 13.2 8.7 7.0 13.2 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain FliD_N PF02465.18 KXZ47700.1 - 2.7 8.8 9.8 1.7 9.4 7.4 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Csm1_N PF18504.1 KXZ47700.1 - 3.2 8.2 7.5 12 6.3 1.6 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF737 PF05300.11 KXZ47700.1 - 6.8 7.0 14.5 7 6.9 12.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF737) SlyX PF04102.12 KXZ47700.1 - 8 7.2 21.9 0.09 13.4 3.0 4.7 3 1 2 5 5 5 0 SlyX LRR_6 PF13516.6 KXZ47702.1 - 3.4e-31 104.6 47.0 0.0074 16.3 0.1 15.5 16 0 0 16 16 16 10 Leucine Rich repeat LRR_4 PF12799.7 KXZ47702.1 - 2.5e-23 81.7 1.3 0.018 15.5 0.4 9.6 6 4 5 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ47702.1 - 7.5e-20 70.5 11.8 4.8e-06 26.2 0.1 8.2 7 2 2 9 9 9 6 Leucine rich repeat LRR_1 PF00560.33 KXZ47702.1 - 2.5e-06 27.3 4.5 93 4.2 0.0 9.6 11 1 0 11 11 11 0 Leucine Rich Repeat DEC-1_N PF04625.13 KXZ47702.1 - 6.4 5.7 5.5 11 4.9 5.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ank_3 PF13606.6 KXZ47704.1 - 1.9e-16 58.5 2.1 0.022 15.3 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 KXZ47704.1 - 2.7e-16 59.9 0.4 0.0004 20.9 0.0 3.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ47704.1 - 2.2e-12 47.0 7.8 0.0046 17.2 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ47704.1 - 2.3e-11 44.0 0.3 0.0033 18.0 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ47704.1 - 1.9e-09 37.5 8.4 0.12 12.9 0.1 5.9 5 1 0 5 5 5 3 Ankyrin repeat Na_H_Exchanger PF00999.21 KXZ47705.1 - 1.4e-41 142.6 11.9 1.7e-41 142.3 11.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PhoR PF11808.8 KXZ47705.1 - 0.0036 17.7 7.3 0.21 12.0 1.2 3.0 2 1 0 2 2 2 2 Phosphate regulon sensor protein PhoR DUF2398 PF09661.10 KXZ47705.1 - 0.0074 15.6 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2398) TraL PF07178.11 KXZ47705.1 - 4.5 7.8 9.7 0.17 12.4 2.2 2.5 3 0 0 3 3 3 0 TraL protein PRK PF00485.18 KXZ47707.1 - 1.5e-15 57.5 0.2 2.8e-14 53.3 0.2 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.21 KXZ47707.1 - 5.4e-10 39.5 0.0 5.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 CYTH domain AAA_33 PF13671.6 KXZ47707.1 - 0.007 16.5 0.1 0.27 11.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXZ47707.1 - 0.037 14.4 0.5 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KXZ47707.1 - 0.05 14.2 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXZ47707.1 - 0.2 10.8 0.1 0.34 10.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF3584 PF12128.8 KXZ47707.1 - 0.22 9.0 2.2 0.31 8.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KAP_NTPase PF07693.14 KXZ47707.1 - 0.24 10.6 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain HAUS-augmin3 PF14932.6 KXZ47707.1 - 0.3 10.6 2.6 0.49 9.9 2.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Apolipoprotein PF01442.18 KXZ47707.1 - 0.39 10.6 5.4 0.15 11.9 2.7 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SKA2 PF16740.5 KXZ47707.1 - 0.39 10.5 2.0 0.44 10.3 0.8 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Pkinase PF00069.25 KXZ47708.1 - 0.13 11.6 0.0 0.63 9.4 0.0 1.9 1 1 0 1 1 1 0 Protein kinase domain FA_desaturase PF00487.24 KXZ47709.1 - 7.1e-35 121.1 35.0 9.3e-35 120.7 35.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase FdhE PF04216.12 KXZ47709.1 - 0.089 12.7 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation NRDE-2 PF08424.10 KXZ47710.1 - 1.5e-62 211.6 0.0 3.8e-62 210.3 0.0 1.7 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference DUF4778 PF16008.5 KXZ47710.1 - 0.17 11.9 2.2 0.27 11.2 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Snf7 PF03357.21 KXZ47711.1 - 2.3e-31 108.7 20.5 3.5e-31 108.1 20.5 1.2 1 0 0 1 1 1 1 Snf7 IL34 PF15036.6 KXZ47711.1 - 0.0058 16.7 4.3 0.38 10.8 0.5 2.5 1 1 1 2 2 2 2 Interleukin 34 VPS28 PF03997.12 KXZ47711.1 - 0.071 12.8 7.9 0.84 9.3 0.3 2.3 1 1 1 2 2 2 0 VPS28 protein Bot1p PF12298.8 KXZ47711.1 - 3.3 7.8 11.2 1 9.5 7.4 2.0 1 1 1 2 2 2 0 Eukaryotic mitochondrial regulator protein DUF1421 PF07223.11 KXZ47712.1 - 1.6e-07 31.1 0.1 2.9e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain (DUF1421) Baculo_PEP_C PF04513.12 KXZ47712.1 - 0.029 14.4 0.2 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PDEase_I PF00233.19 KXZ47713.1 - 1e-68 231.7 0.0 2.8e-68 230.2 0.0 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF3738 PF12543.8 KXZ47713.1 - 3.7e-08 33.7 79.9 10 6.2 0.2 17.2 1 1 13 15 15 15 11 Protein of unknown function (DUF3738) HALZ PF02183.18 KXZ47713.1 - 4.1 7.7 23.8 3.9 7.8 2.6 6.4 6 0 0 6 6 6 0 Homeobox associated leucine zipper CTP_transf_like PF01467.26 KXZ47714.1 - 0.00052 20.2 0.0 0.00073 19.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like VWA_3 PF13768.6 KXZ47715.1 - 3.6e-12 46.5 0.0 1.5e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXZ47715.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain CAP PF00188.26 KXZ47716.1 - 4.7e-15 56.5 1.1 8e-15 55.8 1.1 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Cnd2 PF05786.14 KXZ47717.1 - 4.8e-45 154.5 1.0 1e-28 100.5 0.1 3.5 2 2 0 2 2 2 2 Condensin complex subunit 2 CNDH2_N PF06278.11 KXZ47717.1 - 0.0061 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal WBP-1 PF11669.8 KXZ47718.1 - 0.34 11.6 2.5 1 10.0 2.5 1.8 1 0 0 1 1 1 0 WW domain-binding protein 1 Neur_chan_memb PF02932.16 KXZ47718.1 - 4.8 7.2 5.5 7.8 6.5 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Taxilin PF09728.9 KXZ47719.1 - 0.0043 16.3 0.3 0.0078 15.4 0.3 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein GAS PF13851.6 KXZ47719.1 - 0.13 11.6 10.7 1.4 8.2 8.8 3.2 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 KXZ47719.1 - 0.26 9.4 7.7 0.43 8.7 7.7 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Atg14 PF10186.9 KXZ47719.1 - 0.49 9.4 11.0 0.071 12.2 5.7 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 KXZ47719.1 - 0.85 9.8 9.8 0.52 10.5 6.3 2.3 1 1 1 2 2 2 0 Tropomyosin like Spc7 PF08317.11 KXZ47719.1 - 1.3 7.9 15.7 0.061 12.2 7.9 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein FlxA PF14282.6 KXZ47719.1 - 4.6 7.3 12.6 2.6 8.1 2.2 2.7 2 0 0 2 2 2 0 FlxA-like protein DUF720 PF05302.11 KXZ47719.1 - 6.1 6.7 8.9 0.69 9.8 2.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF720) DUF724 PF05266.14 KXZ47719.1 - 6.3 6.6 8.5 1.3 8.8 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 KXZ47719.1 - 7.4 6.6 13.6 7.5 6.6 0.1 3.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.9 KXZ47719.1 - 8.9 6.5 14.0 0.2 11.9 4.5 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Pro_dh PF01619.18 KXZ47720.1 - 4.8e-41 141.2 0.0 6.4e-40 137.5 0.0 2.4 2 1 0 2 2 2 1 Proline dehydrogenase EF-hand_6 PF13405.6 KXZ47720.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KXZ47720.1 - 0.22 12.0 0.0 0.51 10.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair RAMA PF18755.1 KXZ47722.1 - 4e-22 78.7 0.0 7.3e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated Prok-JAB PF14464.6 KXZ47722.1 - 0.0018 18.0 0.1 0.004 16.9 0.1 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CAF1A PF12253.8 KXZ47722.1 - 6.1 7.1 8.3 16 5.8 8.3 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A DUF155 PF02582.14 KXZ47725.1 - 3.1e-44 151.2 0.0 4e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 KBP_C PF12309.8 KXZ47726.1 - 8.4e-54 183.4 0.0 5.3e-53 180.8 0.0 2.1 1 1 0 1 1 1 1 KIF-1 binding protein C terminal TPR_12 PF13424.6 KXZ47726.1 - 0.0032 17.7 0.2 0.0032 17.7 0.2 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ47726.1 - 0.0081 16.0 1.5 0.049 13.5 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ47726.1 - 0.15 12.0 0.1 0.15 12.0 0.1 3.5 4 1 1 5 5 5 0 Tetratricopeptide repeat O-FucT PF10250.9 KXZ47728.1 - 0.00028 20.7 0.1 0.00065 19.5 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 KXZ47729.1 - 3.2e-06 27.1 0.0 6.4e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Acetyltransf_1 PF00583.25 KXZ47730.1 - 5.9e-16 58.8 0.1 7.8e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ47730.1 - 1e-08 35.1 0.3 1.3e-08 34.8 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ47730.1 - 3.2e-08 33.9 0.1 4.3e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ47730.1 - 5.2e-07 29.5 0.1 7.8e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXZ47730.1 - 4.3e-05 23.6 0.1 6.3e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXZ47730.1 - 0.00038 20.6 0.0 0.0005 20.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AP2 PF00847.20 KXZ47731.1 - 4.5e-13 49.2 1.8 2.5e-12 46.8 1.8 2.4 1 0 0 1 1 1 1 AP2 domain TFIIA PF03153.13 KXZ47731.1 - 0.00068 19.7 66.5 0.001 19.1 66.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Piezo_RRas_bdg PF12166.8 KXZ47731.1 - 7.3 5.7 9.2 12 5.1 9.2 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain PTPLA PF04387.14 KXZ47734.1 - 6.2e-48 162.6 3.4 9.4e-48 162.0 3.4 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Complex1_LYR PF05347.15 KXZ47735.1 - 5e-14 52.1 1.6 5.6e-14 51.9 1.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXZ47735.1 - 5.4e-06 27.1 3.9 5.6e-06 27.0 3.9 1.0 1 0 0 1 1 1 1 Complex1_LYR-like DUF2252 PF10009.9 KXZ47735.1 - 0.031 13.4 0.5 0.035 13.2 0.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Complex1_LYR_1 PF13232.6 KXZ47735.1 - 0.061 13.9 3.6 1.2 9.8 0.5 2.1 1 1 1 2 2 2 0 Complex1_LYR-like TPT PF03151.16 KXZ47736.1 - 4.1e-25 88.7 8.0 4.9e-25 88.5 8.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ47736.1 - 0.00074 19.7 30.9 0.011 15.8 12.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family Na_Ca_ex PF01699.24 KXZ47737.1 - 4.9e-31 107.7 30.4 5.3e-17 62.2 13.6 2.9 2 1 0 2 2 2 2 Sodium/calcium exchanger protein SelK_SelG PF10961.8 KXZ47737.1 - 0.15 12.7 5.5 1 10.0 5.5 2.4 1 1 0 1 1 1 0 Selenoprotein SelK_SelG DUF5308 PF17233.2 KXZ47738.1 - 0.044 14.0 0.2 0.053 13.7 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF1919 PF08942.10 KXZ47739.1 - 0.28 10.6 0.0 0.42 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) DNA_pol_A PF00476.20 KXZ47740.1 - 1.4e-63 215.2 0.0 3.4e-63 214.0 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KXZ47740.1 - 1.5e-07 31.3 0.0 9.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease HATPase_c PF02518.26 KXZ47741.1 - 7.7e-27 94.0 0.2 2e-26 92.7 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXZ47741.1 - 1.3e-25 89.7 0.0 2.9e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Guanylate_cyc PF00211.20 KXZ47741.1 - 2.9e-21 75.9 0.0 5.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Bac_rhodopsin PF01036.18 KXZ47741.1 - 1.2e-17 64.3 13.7 1.8e-17 63.6 13.7 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HisKA PF00512.25 KXZ47741.1 - 1.4e-13 50.7 1.8 5.6e-12 45.5 0.0 3.6 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Totivirus_coat PF05518.11 KXZ47741.1 - 0.49 8.4 3.4 5.2 5.0 0.3 2.2 2 0 0 2 2 2 0 Totivirus coat protein SAM_1 PF00536.30 KXZ47742.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LRR_6 PF13516.6 KXZ47743.1 - 0.053 13.6 0.5 37 4.7 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 KXZ47743.1 - 0.29 11.6 1.4 4.1 8.0 0.2 3.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Adeno_E3B PF03376.14 KXZ47744.1 - 0.27 11.5 1.2 0.49 10.7 1.2 1.3 1 0 0 1 1 1 0 Adenovirus E3B protein NCBP3 PF10309.9 KXZ47745.1 - 0.002 17.9 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 PsbP PF01789.16 KXZ47746.1 - 1.7e-34 119.2 0.0 2.2e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 PsbP B12-binding_2 PF02607.17 KXZ47747.1 - 0.76 10.3 8.3 2.9 8.4 0.9 3.5 3 0 0 3 3 3 0 B12 binding domain SBF_like PF13593.6 KXZ47748.1 - 1.1e-47 162.9 24.2 7.1e-43 147.1 23.5 2.0 2 0 0 2 2 2 2 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KXZ47748.1 - 1.2e-11 44.6 16.8 1.2e-11 44.6 16.8 2.4 1 1 1 2 2 2 1 Sodium Bile acid symporter family Popeye PF04831.13 KXZ47748.1 - 0.082 13.1 2.0 0.9 9.7 0.3 2.5 2 0 0 2 2 2 0 Popeye protein conserved region DUF5392 PF17370.2 KXZ47748.1 - 0.24 11.5 1.9 0.32 11.1 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5392) zf-RING_13 PF17977.1 KXZ47750.1 - 0.2 11.8 9.5 1.3 9.2 2.8 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain ShK PF01549.24 KXZ47750.1 - 2 9.0 19.3 0.41 11.2 4.6 2.5 2 0 0 2 2 2 0 ShK domain-like PGAP1 PF07819.13 KXZ47752.1 - 6.9e-24 84.8 0.0 2.9e-23 82.8 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KXZ47752.1 - 0.0019 17.5 2.6 0.004 16.4 0.2 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KXZ47752.1 - 0.0068 15.9 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KXZ47752.1 - 0.06 13.0 0.1 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KXZ47752.1 - 0.073 12.9 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 KXZ47752.1 - 0.074 13.2 0.2 0.17 12.0 0.1 1.6 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_5 PF12695.7 KXZ47752.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family SR-25 PF10500.9 KXZ47752.1 - 0.35 10.5 2.9 0.52 9.9 2.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPV_P10 PF05531.12 KXZ47754.1 - 1.1e-05 25.8 18.2 0.014 15.9 3.0 2.5 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 KXZ47754.1 - 2e-05 24.7 9.8 0.00097 19.2 3.7 2.4 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 KXZ47754.1 - 0.0001 22.6 17.0 0.00016 22.0 17.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IFT57 PF10498.9 KXZ47754.1 - 0.00038 19.5 13.9 0.00057 19.0 13.9 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 MscS_porin PF12795.7 KXZ47754.1 - 0.00041 20.0 32.2 0.036 13.6 15.7 2.2 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain Spc7 PF08317.11 KXZ47754.1 - 0.00043 19.2 10.7 0.00062 18.7 10.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4201 PF13870.6 KXZ47754.1 - 0.00056 19.7 5.2 0.00078 19.2 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) GAS PF13851.6 KXZ47754.1 - 0.00093 18.6 9.8 0.1 12.0 0.7 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KXZ47754.1 - 0.0013 17.0 6.6 0.0016 16.7 6.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Fez1 PF06818.15 KXZ47754.1 - 0.0018 18.8 6.4 0.002 18.6 6.4 1.1 1 0 0 1 1 1 1 Fez1 Exonuc_VII_L PF02601.15 KXZ47754.1 - 0.002 17.8 7.3 0.002 17.7 7.3 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit ERM PF00769.19 KXZ47754.1 - 0.0045 16.8 7.7 0.0052 16.6 7.7 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family WEMBL PF05701.11 KXZ47754.1 - 0.0051 15.6 6.5 0.0059 15.4 6.5 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Cast PF10174.9 KXZ47754.1 - 0.0051 15.1 5.7 0.0061 14.9 5.7 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone HMMR_N PF15905.5 KXZ47754.1 - 0.0073 15.8 9.1 0.0094 15.5 9.1 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 KXZ47754.1 - 0.008 15.8 9.4 0.0089 15.6 9.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein MitMem_reg PF13012.6 KXZ47754.1 - 0.013 15.9 4.7 0.023 15.1 4.7 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF4349 PF14257.6 KXZ47754.1 - 0.014 14.8 14.0 0.031 13.7 14.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4795 PF16043.5 KXZ47754.1 - 0.015 14.9 6.5 0.02 14.5 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Myosin_tail_1 PF01576.19 KXZ47754.1 - 0.02 12.8 9.2 0.023 12.6 9.2 1.1 1 0 0 1 1 1 0 Myosin tail Atg14 PF10186.9 KXZ47754.1 - 0.025 13.7 3.4 0.033 13.3 3.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM184 PF15665.5 KXZ47754.1 - 0.028 14.2 11.2 0.042 13.6 11.2 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Leu_zip PF15294.6 KXZ47754.1 - 0.04 13.4 9.9 0.053 13.0 9.9 1.2 1 0 0 1 1 1 0 Leucine zipper DUF4665 PF15679.5 KXZ47754.1 - 0.041 14.5 8.3 0.21 12.2 2.9 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) DUF724 PF05266.14 KXZ47754.1 - 0.044 13.6 6.8 0.061 13.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KXZ47754.1 - 0.07 11.0 6.0 0.079 10.9 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 KXZ47754.1 - 0.074 13.4 17.2 2.2 8.7 16.9 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) CC2-LZ PF16516.5 KXZ47754.1 - 0.082 13.3 12.5 1.5 9.2 4.1 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAM76 PF16046.5 KXZ47754.1 - 0.087 12.2 6.9 0.1 11.9 6.9 1.1 1 0 0 1 1 1 0 FAM76 protein TMPIT PF07851.13 KXZ47754.1 - 0.092 12.0 8.1 0.11 11.7 8.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Golgin_A5 PF09787.9 KXZ47754.1 - 0.092 12.2 11.7 0.14 11.6 11.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Pox_F11 PF04943.12 KXZ47754.1 - 0.097 11.7 1.6 0.12 11.4 1.6 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein DUF745 PF05335.13 KXZ47754.1 - 0.1 12.3 21.5 0.13 12.0 21.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KXZ47754.1 - 0.11 12.6 12.5 0.47 10.5 12.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-Q PF13094.6 KXZ47754.1 - 0.11 12.7 10.9 0.23 11.6 2.5 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.10 KXZ47754.1 - 0.12 12.6 10.5 0.24 11.6 10.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PI3K_P85_iSH2 PF16454.5 KXZ47754.1 - 0.13 11.8 9.9 0.23 11.0 9.9 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3086 PF11285.8 KXZ47754.1 - 0.14 11.3 7.7 0.19 10.8 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF4763 PF15960.5 KXZ47754.1 - 0.14 11.4 11.7 0.25 10.6 11.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CENP-F_leu_zip PF10473.9 KXZ47754.1 - 0.17 11.9 8.2 0.27 11.2 8.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 KXZ47754.1 - 0.17 10.5 6.2 0.28 9.8 6.2 1.4 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 KXZ47754.1 - 0.2 10.2 4.1 0.26 9.9 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4200 PF13863.6 KXZ47754.1 - 0.2 12.0 5.9 0.36 11.2 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 KXZ47754.1 - 0.21 11.7 7.1 0.31 11.2 7.1 1.3 1 0 0 1 1 1 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 KXZ47754.1 - 0.23 11.7 9.3 0.34 11.1 9.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 KXZ47754.1 - 0.24 11.4 15.0 1.9 8.5 14.8 2.0 1 1 1 2 2 2 0 Laminin Domain II SlyX PF04102.12 KXZ47754.1 - 0.25 12.0 24.9 0.23 12.1 4.3 2.6 2 1 1 3 3 2 0 SlyX HemX PF04375.14 KXZ47754.1 - 0.26 10.5 21.9 0.45 9.7 21.9 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase HOOK PF05622.12 KXZ47754.1 - 0.26 9.4 10.7 0.31 9.1 10.7 1.1 1 0 0 1 1 1 0 HOOK protein Tropomyosin PF00261.20 KXZ47754.1 - 0.28 10.5 10.2 0.73 9.1 10.2 1.6 1 1 1 2 2 2 0 Tropomyosin CMV_1a PF12467.8 KXZ47754.1 - 0.29 11.5 3.4 0.4 11.0 3.4 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF812 PF05667.11 KXZ47754.1 - 0.3 9.9 14.2 0.38 9.6 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YscO-like PF16789.5 KXZ47754.1 - 0.32 11.0 10.0 0.4 10.7 10.0 1.1 1 0 0 1 1 1 0 YscO-like protein DUF4407 PF14362.6 KXZ47754.1 - 0.33 10.2 15.4 0.51 9.6 15.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1043 PF06295.12 KXZ47754.1 - 0.36 10.8 15.3 0.46 10.5 6.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) YscO PF07321.12 KXZ47754.1 - 0.38 10.7 17.2 1.2 9.1 17.1 1.8 1 1 1 2 2 2 0 Type III secretion protein YscO DUF3450 PF11932.8 KXZ47754.1 - 0.41 9.9 21.0 0.59 9.4 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sec8_exocyst PF04048.14 KXZ47754.1 - 0.43 10.5 9.4 10 6.0 4.4 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain UPF0231 PF06062.11 KXZ47754.1 - 0.47 10.7 7.8 1.1 9.5 7.2 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) UPF0242 PF06785.11 KXZ47754.1 - 0.77 9.8 9.7 1 9.4 9.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 KXZ47754.1 - 0.87 9.9 11.5 3.7 7.9 11.3 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 KXZ47754.1 - 0.9 9.3 13.5 9.4 6.0 13.6 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 Flavodoxin_3 PF12641.7 KXZ47754.1 - 0.94 9.1 6.2 8.2 6.1 1.1 3.3 1 1 3 4 4 4 0 Flavodoxin domain SKA1 PF07160.12 KXZ47754.1 - 0.95 9.3 10.1 1.9 8.3 10.0 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FliJ PF02050.16 KXZ47754.1 - 0.97 9.7 22.8 1.3 9.2 13.5 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein Sec34 PF04136.15 KXZ47754.1 - 0.97 9.3 12.5 5 7.0 11.1 2.1 1 1 1 2 2 2 0 Sec34-like family BRE1 PF08647.11 KXZ47754.1 - 1 9.5 13.3 1.8 8.7 13.3 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase RmuC PF02646.16 KXZ47754.1 - 1.5 7.9 18.8 0.61 9.2 9.2 2.1 1 1 1 2 2 2 0 RmuC family APG6_N PF17675.1 KXZ47754.1 - 1.6 9.2 11.8 2.2 8.8 11.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Mod_r PF07200.13 KXZ47754.1 - 1.7 8.8 13.2 8.8 6.4 12.8 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein KxDL PF10241.9 KXZ47754.1 - 1.8 8.9 12.0 10 6.5 3.1 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein KELK PF15796.5 KXZ47754.1 - 2.1 8.8 10.7 26 5.4 10.4 2.2 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HAP1_N PF04849.13 KXZ47754.1 - 2.1 7.4 16.6 11 5.1 16.5 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF148 PF02520.17 KXZ47754.1 - 2.2 8.5 18.5 4.1e+02 1.1 18.5 2.4 1 1 0 1 1 1 0 Domain of unknown function DUF148 Tweety PF04906.13 KXZ47754.1 - 2.2 6.8 9.4 3.1 6.4 9.4 1.3 1 0 0 1 1 1 0 Tweety HAUS-augmin3 PF14932.6 KXZ47754.1 - 2.4 7.7 15.6 3 7.4 15.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DHR10 PF18595.1 KXZ47754.1 - 2.5 8.2 18.2 11 6.2 8.8 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain AIP3 PF03915.13 KXZ47754.1 - 2.8 6.9 11.0 3.4 6.7 11.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Synaptobrevin PF00957.21 KXZ47754.1 - 2.9 7.8 12.0 10 6.0 4.2 2.6 1 1 0 2 2 2 0 Synaptobrevin Cob_adeno_trans PF01923.18 KXZ47754.1 - 3 8.0 7.7 6.9 6.8 7.6 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase TPR_MLP1_2 PF07926.12 KXZ47754.1 - 3.3 7.8 19.2 1.4 9.0 16.5 1.8 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 KXZ47754.1 - 3.6 7.9 12.9 1.4e+03 -0.4 12.9 2.5 1 1 0 1 1 1 0 ABC transporter C-terminal domain End3 PF12761.7 KXZ47754.1 - 4 7.6 13.2 85 3.2 13.2 2.2 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF2968 PF11180.8 KXZ47754.1 - 4.1 7.0 28.9 8.8 5.9 28.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Seryl_tRNA_N PF02403.22 KXZ47754.1 - 4.2 7.7 7.8 13 6.1 7.8 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain COG6 PF06419.11 KXZ47754.1 - 4.3 5.4 12.4 0.85 7.8 6.6 1.9 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 DUF4446 PF14584.6 KXZ47754.1 - 4.4 7.3 7.1 11 6.0 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF773 PF05600.12 KXZ47754.1 - 5.2 5.7 11.4 7.2 5.2 11.4 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 FOXP-CC PF16159.5 KXZ47754.1 - 5.3 7.7 18.0 5.7 7.7 5.0 3.0 1 1 2 3 3 3 0 FOXP coiled-coil domain Phage_GPO PF05929.11 KXZ47754.1 - 5.6 6.5 15.4 7.8 6.0 15.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Csm1_N PF18504.1 KXZ47754.1 - 6.8 7.1 17.1 18 5.8 2.0 3.1 1 1 0 2 2 2 0 Csm1 N-terminal domain YabA PF06156.13 KXZ47754.1 - 7.6 7.2 11.4 3.3e+02 2.0 11.4 2.4 1 1 0 1 1 1 0 Initiation control protein YabA HisKA_3 PF07730.13 KXZ47754.1 - 7.8 7.1 15.6 6.6 7.3 6.4 2.5 1 1 1 2 2 2 0 Histidine kinase VlpA_repeat PF04649.12 KXZ47754.1 - 8.3 6.9 12.5 92 3.7 0.3 4.8 4 0 0 4 4 4 0 Mycoplasma hyorhinis VlpA repeat ADIP PF11559.8 KXZ47754.1 - 9.4 6.3 18.8 8.1 6.5 8.6 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PNP_UDP_1 PF01048.20 KXZ47755.1 - 4.3e-30 104.7 0.1 6.8e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily SAP PF02037.27 KXZ47756.1 - 8.1e-08 31.9 0.1 1.8e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 SAP domain F-box-like PF12937.7 KXZ47756.1 - 0.35 10.8 1.9 1.2 9.1 0.0 2.6 2 1 0 2 2 2 0 F-box-like SWIRM-assoc_2 PF16496.5 KXZ47757.1 - 3.9e-44 151.2 7.2 3.1e-42 144.9 0.0 2.2 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 KXZ47757.1 - 5.1e-21 74.8 0.0 8.7e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KXZ47757.1 - 6e-16 58.2 9.1 6e-16 58.2 9.1 4.0 4 1 1 5 5 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KXZ47757.1 - 9.1e-11 41.8 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KXZ47757.1 - 0.0028 17.4 0.4 0.0048 16.7 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Band_3_cyto PF07565.13 KXZ47757.1 - 0.47 10.2 14.5 0.8 9.5 14.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.12 KXZ47757.1 - 0.55 10.0 15.6 1.2 8.9 15.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KXZ47757.1 - 0.71 8.6 16.1 1.2 7.8 16.1 1.3 1 0 0 1 1 1 0 Presenilin DUF5427 PF10310.9 KXZ47757.1 - 0.71 8.8 23.3 1.5 7.7 23.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF913 PF06025.12 KXZ47757.1 - 0.83 8.6 8.4 1.3 7.9 8.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 KXZ47757.1 - 0.92 9.6 10.2 2.2 8.4 10.2 1.6 1 0 0 1 1 1 0 DDHD domain DUF1387 PF07139.11 KXZ47757.1 - 1.1 9.0 15.7 1.9 8.1 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SpoIIP PF07454.11 KXZ47757.1 - 3.2 7.1 13.6 5.2 6.4 13.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pkinase_fungal PF17667.1 KXZ47757.1 - 4 6.1 9.5 7.3 5.3 8.9 1.6 2 0 0 2 2 2 0 Fungal protein kinase Neur_chan_memb PF02932.16 KXZ47757.1 - 4.4 7.3 11.2 9.2 6.2 11.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paf1 PF03985.13 KXZ47757.1 - 4.7 6.1 20.4 7.6 5.4 20.4 1.2 1 0 0 1 1 1 0 Paf1 V_ATPase_I PF01496.19 KXZ47757.1 - 4.8 5.0 14.5 6.8 4.5 14.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 KXZ47757.1 - 4.9 5.8 14.3 7.4 5.2 14.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2464 PF10240.9 KXZ47757.1 - 6.4 6.3 16.0 0.034 13.7 6.9 1.7 2 0 0 2 2 1 0 Multivesicular body subunit 12 eIF-3_zeta PF05091.12 KXZ47757.1 - 6.6 5.6 19.1 10 4.9 19.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 KXZ47757.1 - 6.7 4.9 12.8 10 4.3 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Dynactin_p62 PF05502.13 KXZ47757.1 - 6.8 5.3 11.1 10 4.8 11.1 1.1 1 0 0 1 1 1 0 Dynactin p62 family DUF3464 PF11947.8 KXZ47757.1 - 7.8 6.2 15.7 2.7 7.7 10.8 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CPSF100_C PF13299.6 KXZ47757.1 - 8.5 6.5 15.2 16 5.6 11.5 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Hamartin PF04388.12 KXZ47757.1 - 8.5 4.9 19.0 0.0034 16.1 5.9 1.8 2 0 0 2 2 1 0 Hamartin protein Lin-8 PF03353.15 KXZ47757.1 - 9.9 5.6 20.7 17 4.9 20.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EST1_DNA_bind PF10373.9 KXZ47758.1 - 1e-35 123.6 0.0 1.4e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KXZ47758.1 - 3.5e-20 73.0 0.0 1.2e-10 42.1 0.0 2.4 2 0 0 2 2 2 2 Telomerase activating protein Est1 HEAT PF02985.22 KXZ47758.1 - 0.018 15.2 0.1 0.49 10.8 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat HEAT PF02985.22 KXZ47760.1 - 2.6e-06 27.2 19.1 0.042 14.1 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KXZ47760.1 - 0.029 14.7 36.0 0.93 9.9 1.8 6.6 6 1 0 6 6 6 0 HEAT repeats Arm PF00514.23 KXZ47760.1 - 0.39 10.8 4.8 3.4 7.8 0.1 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat LRR_9 PF14580.6 KXZ47761.1 - 8.4e-13 48.2 0.0 1.4e-12 47.5 0.0 1.3 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KXZ47761.1 - 3.2e-11 43.3 1.4 0.0004 20.7 0.0 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ47761.1 - 6.1e-10 38.7 14.6 1.3e-05 24.8 0.1 2.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KXZ47761.1 - 0.02 15.4 1.1 48 5.1 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KXZ47761.1 - 0.82 9.9 7.2 14 6.0 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeat EF-hand_1 PF00036.32 KXZ47762.1 - 1.3e-21 74.5 4.9 2.1e-06 26.9 0.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KXZ47762.1 - 2.5e-18 64.4 7.6 2e-05 24.2 0.0 4.4 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KXZ47762.1 - 1.5e-17 63.8 4.1 2e-10 41.0 0.9 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ47762.1 - 1.6e-12 46.3 9.2 0.0005 19.4 0.0 4.1 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KXZ47762.1 - 2e-11 43.5 7.1 8.6e-05 22.3 0.6 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KXZ47762.1 - 1.6e-05 24.7 0.2 0.058 13.4 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXZ47762.1 - 0.00044 20.5 0.0 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXZ47762.1 - 0.017 15.5 0.1 0.078 13.3 0.0 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 KXZ47762.1 - 0.08 13.3 0.9 18 5.8 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain RRM_1 PF00076.22 KXZ47764.1 - 3.7e-26 90.7 0.0 2.9e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ47764.1 - 0.0036 17.4 0.1 0.7 10.1 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif RRM_8 PF11835.8 KXZ47764.1 - 0.0058 16.8 2.6 0.0089 16.2 0.0 2.5 2 1 1 3 3 3 1 RRM-like domain RRM_5 PF13893.6 KXZ47764.1 - 0.08 12.5 0.0 0.62 9.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vpu PF00558.19 KXZ47765.1 - 0.34 10.7 5.7 0.16 11.7 0.6 2.7 3 0 0 3 3 3 0 Vpu protein Ribosomal_S10 PF00338.22 KXZ47767.1 - 8.7e-29 99.6 0.0 1.3e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GRDP-like PF07173.12 KXZ47768.1 - 9.4e-13 49.0 0.0 2e-10 41.5 0.0 2.2 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like MRP-S26 PF14943.6 KXZ47769.1 - 1.9e-08 34.4 13.7 2.3e-08 34.1 13.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 DUF3381 PF11861.8 KXZ47769.1 - 1.3 8.8 17.8 1.9 8.3 17.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Fib_alpha PF08702.10 KXZ47770.1 - 0.22 11.7 6.9 0.8 9.9 1.8 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KXZ47770.1 - 1.3 7.9 27.8 0.67 8.8 1.0 3.4 3 1 0 3 3 3 0 Spc7 kinetochore protein DisA-linker PF10635.9 KXZ47770.1 - 1.5 8.6 6.0 0.2 11.5 0.2 2.4 3 0 0 3 3 3 0 DisA bacterial checkpoint controller linker region ubiquitin PF00240.23 KXZ47771.1 - 4.7e-08 32.7 0.0 8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXZ47771.1 - 0.0055 16.5 0.0 0.0085 15.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXZ47771.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain MoaC PF01967.21 KXZ47772.1 - 5.9e-47 159.2 3.5 6.8e-47 159.0 3.5 1.0 1 0 0 1 1 1 1 MoaC family E1-N PF14463.6 KXZ47772.1 - 0.016 15.1 5.3 0.027 14.3 5.3 1.4 1 1 0 1 1 1 0 E1 N-terminal domain E3_UbLigase_EDD PF11547.8 KXZ47772.1 - 0.046 13.4 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD TLC PF03219.14 KXZ47773.1 - 0.03 13.0 3.6 0.35 9.6 0.0 2.6 2 1 1 3 3 3 0 TLC ATP/ADP transporter U1snRNP70_N PF12220.8 KXZ47774.1 - 2.7 8.7 9.2 13 6.5 9.2 2.1 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ribosomal_S19 PF00203.21 KXZ47775.1 - 1.3e-33 114.7 1.1 1.7e-33 114.3 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 AFG1_ATPase PF03969.16 KXZ47776.1 - 9.3e-60 202.4 0.0 2.7e-23 82.4 0.0 4.8 5 1 0 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 KXZ47776.1 - 0.00019 21.9 1.3 0.00019 21.9 1.3 3.1 2 1 1 3 3 3 1 AAA ATPase domain HAD_2 PF13419.6 KXZ47777.1 - 7.6e-15 55.4 0.0 9.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ47777.1 - 7.5e-08 32.9 0.0 1.8e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ47777.1 - 3.8e-07 30.7 0.2 5.5e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HTH_29 PF13551.6 KXZ47777.1 - 0.051 13.6 0.1 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix Hydrolase_6 PF13344.6 KXZ47777.1 - 0.2 11.8 0.0 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HRDC PF00570.23 KXZ47778.1 - 2.3e-18 65.9 0.0 3.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 HRDC domain HHH PF00633.23 KXZ47778.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF763 PF05559.11 KXZ47778.1 - 0.096 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Ecm33 PF12454.8 KXZ47779.1 - 0.07 13.3 0.7 0.07 13.3 0.7 3.8 4 0 0 4 4 4 0 GPI-anchored cell wall organization protein Mod_r PF07200.13 KXZ47780.1 - 1e-21 77.5 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF3417 PF11897.8 KXZ47780.1 - 0.084 13.3 0.2 2.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) Alpha-amylase PF00128.24 KXZ47781.1 - 7.4e-20 71.8 0.0 4e-19 69.4 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amyl_C2 PF07821.12 KXZ47781.1 - 7.7e-19 67.7 0.2 1.5e-18 66.8 0.2 1.5 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain ACT PF01842.25 KXZ47781.1 - 0.019 14.7 0.1 0.048 13.4 0.1 1.7 1 0 0 1 1 1 0 ACT domain Glyco_hydro_70 PF02324.16 KXZ47781.1 - 0.075 11.2 0.0 0.36 9.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 Myosin_N PF02736.19 KXZ47781.1 - 0.33 10.8 1.7 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain ubiquitin PF00240.23 KXZ47782.1 - 1.2e-17 63.5 0.0 7.3e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KXZ47782.1 - 9.5e-11 41.4 0.0 4.9e-07 29.5 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KXZ47782.1 - 0.019 15.0 0.4 9 6.4 0.0 3.3 2 1 1 3 3 3 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KXZ47782.1 - 0.049 13.6 0.1 2.1 8.3 0.0 2.5 2 2 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain NYD-SP28 PF14772.6 KXZ47783.1 - 3.3e-29 100.9 9.5 3.3e-29 100.9 9.5 5.2 3 1 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 KXZ47783.1 - 4.7e-21 74.6 1.9 4.7e-21 74.6 1.9 5.6 4 1 2 6 6 6 1 Sperm tail C-terminal domain EzrA PF06160.12 KXZ47783.1 - 0.0088 14.3 35.1 0.062 11.5 9.6 2.3 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Ovate PF04844.13 KXZ47783.1 - 0.088 12.8 0.8 4.4 7.4 0.0 2.9 2 0 0 2 2 2 0 Transcriptional repressor, ovate Baculo_PEP_C PF04513.12 KXZ47783.1 - 9.8 6.2 8.3 2.2 8.3 0.1 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Endonuclease_NS PF01223.23 KXZ47785.1 - 1.4e-41 142.8 0.0 1.3e-31 110.2 0.0 2.3 1 1 1 2 2 2 2 DNA/RNA non-specific endonuclease Methyltransf_11 PF08241.12 KXZ47786.1 - 3.8e-11 43.5 0.0 5.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ47786.1 - 6.6e-08 33.2 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ47786.1 - 5.8e-06 26.2 0.0 7.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ47786.1 - 0.04 14.7 0.0 0.065 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Kri1 PF05178.12 KXZ47787.1 - 0.043 14.4 0.1 0.072 13.7 0.0 1.4 1 1 0 1 1 1 0 KRI1-like family RNA_pol_3_Rpc31 PF11705.8 KXZ47788.1 - 2.8e-08 34.3 9.0 3.5e-08 34.0 9.0 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CreA PF05981.12 KXZ47789.1 - 2.6e-30 105.1 0.0 3.9e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 CreA protein LRR_8 PF13855.6 KXZ47790.1 - 2.9e-05 23.7 1.6 0.021 14.6 0.0 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KXZ47790.1 - 0.13 12.3 0.2 5.1 7.4 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 KXZ47790.1 - 0.7 10.4 5.6 15 6.2 0.1 4.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) RSN1_7TM PF02714.15 KXZ47791.1 - 2.5e-57 194.3 26.5 3.3e-55 187.3 26.5 2.2 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXZ47791.1 - 1e-36 126.1 1.1 1e-36 126.1 1.1 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXZ47791.1 - 1.5e-19 70.9 1.2 1.5e-19 70.9 1.2 2.8 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter ABATE PF07336.11 KXZ47791.1 - 0.046 14.4 0.0 0.046 14.4 0.0 3.4 4 1 0 4 4 4 0 Putative stress-induced transcription regulator RSN1_7TM PF02714.15 KXZ47792.1 - 4.3e-60 203.4 25.6 8.7e-60 202.3 25.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXZ47792.1 - 4e-28 98.1 5.7 4e-28 98.1 5.7 3.5 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXZ47792.1 - 3e-20 73.2 0.0 3e-20 73.2 0.0 2.8 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter UPF0239 PF06783.11 KXZ47792.1 - 0.099 12.8 4.5 0.6 10.3 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) DUF948 PF06103.11 KXZ47792.1 - 0.73 10.1 3.4 18 5.7 0.6 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) RSN1_TM PF13967.6 KXZ47793.1 - 3.1e-37 127.7 1.1 3.8e-37 127.4 1.1 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport RSN1_7TM PF02714.15 KXZ47794.1 - 1.7e-47 162.0 22.5 1.1e-30 106.8 12.7 2.1 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXZ47794.1 - 5e-20 72.5 0.0 1.1e-19 71.4 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter ABATE PF07336.11 KXZ47794.1 - 0.087 13.5 13.7 0.16 12.7 0.3 2.5 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Pkinase PF00069.25 KXZ47796.1 - 4.2e-13 49.3 0.0 1.8e-12 47.2 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47796.1 - 4.9e-06 26.0 0.0 1.8e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase FANCI_S1 PF14675.6 KXZ47797.1 - 8.4e-11 41.9 0.0 6.4e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 FANCI solenoid 1 Oxysterol_BP PF01237.18 KXZ47798.1 - 0.00024 20.1 0.0 0.15 10.9 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein DUF1631 PF07793.11 KXZ47799.1 - 0.079 11.4 3.4 0.18 10.2 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RecA PF00154.21 KXZ47800.1 - 1.2e-12 47.9 0.0 1.4e-12 47.6 0.0 1.3 1 1 0 1 1 1 1 recA bacterial DNA recombination protein Filament PF00038.21 KXZ47801.1 - 1.8e-05 24.5 15.6 0.0019 17.8 6.0 2.2 1 1 1 2 2 2 2 Intermediate filament protein DUF4763 PF15960.5 KXZ47801.1 - 0.39 10.0 12.4 0.16 11.2 1.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) CENP-H PF05837.12 KXZ47801.1 - 0.46 10.9 22.1 0.46 10.9 10.7 2.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.11 KXZ47801.1 - 0.75 10.0 29.5 0.16 12.1 24.1 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KXZ47801.1 - 0.76 9.6 14.5 3.4 7.5 14.0 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH End3 PF12761.7 KXZ47801.1 - 0.89 9.7 12.3 0.64 10.2 7.2 2.3 1 1 2 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 MPS2 PF17060.5 KXZ47801.1 - 1 8.6 4.3 3.8 6.7 2.0 1.9 1 1 1 2 2 2 0 Monopolar spindle protein 2 Spc7 PF08317.11 KXZ47801.1 - 1.1 8.1 19.9 0.64 8.8 11.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2407_C PF13373.6 KXZ47801.1 - 1.4 9.1 7.9 3.7 7.7 7.0 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain FAM76 PF16046.5 KXZ47801.1 - 1.5 8.2 8.8 3.2 7.0 0.7 2.0 1 1 0 2 2 2 0 FAM76 protein Tropomyosin PF00261.20 KXZ47801.1 - 2.8 7.2 22.7 2.8 7.3 1.2 2.6 2 1 0 2 2 2 0 Tropomyosin NBP1 PF08537.10 KXZ47801.1 - 4.2 6.7 7.1 10 5.4 7.0 1.6 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 CCDC144C PF14915.6 KXZ47801.1 - 6.4 5.8 18.0 70 2.4 18.0 2.0 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region Glyco_hydro_18 PF00704.28 KXZ47802.1 - 2.2e-74 251.0 0.0 3e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LPMO_10 PF03067.15 KXZ47802.1 - 8.6e-25 88.5 0.4 1.4e-24 87.8 0.4 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 KXZ47802.1 - 1.6e-13 50.6 14.6 8.4e-11 41.9 3.2 3.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Sec61_beta PF03911.16 KXZ47804.1 - 6.4e-16 58.1 0.0 9e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 Sec61beta family PsbH PF00737.20 KXZ47804.1 - 0.042 13.6 0.2 0.066 13.0 0.2 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein FAE1_CUT1_RppA PF08392.12 KXZ47805.1 - 1.9e-74 250.6 0.0 4.3e-61 206.7 0.0 2.1 2 0 0 2 2 2 2 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 KXZ47805.1 - 3.3e-09 36.9 0.0 6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 KXZ47805.1 - 1.1e-07 32.0 0.0 7.9e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_N PF00195.19 KXZ47805.1 - 0.0034 16.8 0.1 0.0056 16.1 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Mito_fiss_reg PF05308.11 KXZ47806.1 - 7.1 6.6 10.8 12 5.9 10.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator HSP20 PF00011.21 KXZ47807.1 - 2.8e-30 104.5 0.0 3.3e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXZ47807.1 - 6.8e-07 28.7 0.0 9.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 KXZ47807.1 - 0.14 12.5 0.2 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 BON domain HSP20 PF00011.21 KXZ47808.1 - 2.1e-27 95.3 0.0 2.3e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXZ47808.1 - 2.1e-06 27.2 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 HSP20-like domain found in ArsA LPD7 PF18821.1 KXZ47809.1 - 0.029 14.5 1.5 0.03 14.4 0.1 1.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 LRR_8 PF13855.6 KXZ47811.1 - 2.9e-12 46.2 19.7 1.6e-07 30.9 0.3 4.7 4 0 0 4 4 4 4 Leucine rich repeat Guanylate_cyc PF00211.20 KXZ47811.1 - 8e-09 35.4 0.0 4.3e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 KXZ47811.1 - 0.00025 21.4 23.5 0.0057 17.1 0.2 5.1 1 1 5 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ47811.1 - 0.079 13.6 13.6 6.1 7.8 0.0 6.7 6 1 0 6 6 6 0 Leucine Rich Repeat LPD7 PF18821.1 KXZ47811.1 - 0.46 10.6 2.4 0.69 10.1 0.1 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 HSP20 PF00011.21 KXZ47812.1 - 9.3e-28 96.4 0.0 1.1e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXZ47812.1 - 5.9e-08 32.2 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Amino_oxidase PF01593.24 KXZ47813.1 - 4.1e-86 290.0 0.5 5.8e-86 289.6 0.5 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ47813.1 - 3e-14 53.0 1.0 3e-14 53.0 1.0 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 KXZ47813.1 - 2.7e-10 40.4 0.0 4.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 SWIRM domain FAD_binding_2 PF00890.24 KXZ47813.1 - 4e-06 26.2 1.3 7.8e-06 25.2 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXZ47813.1 - 8.2e-06 25.3 0.6 1.7e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ47813.1 - 1.6e-05 25.4 1.6 0.00011 22.6 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ47813.1 - 2.9e-05 23.6 0.4 5.3e-05 22.7 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXZ47813.1 - 3.2e-05 22.8 0.0 5.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KXZ47813.1 - 4.9e-05 22.7 0.3 0.00011 21.6 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXZ47813.1 - 0.00019 20.6 0.8 0.00029 20.1 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXZ47813.1 - 0.00049 19.4 0.3 0.00091 18.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXZ47813.1 - 0.0011 18.3 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXZ47813.1 - 0.024 13.9 0.1 0.038 13.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXZ47813.1 - 0.056 12.5 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Glu_dehyd_C PF16912.5 KXZ47813.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Sof1 PF04158.14 KXZ47814.1 - 9.7e-30 102.7 9.2 2e-29 101.7 9.2 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KXZ47814.1 - 8.5e-26 89.7 3.3 3.4e-05 24.5 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ47814.1 - 3.2e-05 24.1 0.0 0.63 10.4 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ47814.1 - 0.027 13.4 0.1 0.61 9.0 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 KXZ47814.1 - 0.033 14.2 0.0 51 4.0 0.0 3.4 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region AIRS_C PF02769.22 KXZ47815.1 - 8.2e-25 87.7 0.0 1.2e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KXZ47815.1 - 1.7e-14 54.2 0.2 3e-14 53.4 0.2 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PPDK_N PF01326.19 KXZ47816.1 - 1e-19 71.0 0.0 4.6e-18 65.6 0.0 3.1 1 1 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DSPc PF00782.20 KXZ47816.1 - 0.00094 19.0 0.0 0.0049 16.7 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2934 PF11154.8 KXZ47816.1 - 0.0092 15.6 0.1 0.05 13.3 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) GST_N_3 PF13417.6 KXZ47817.1 - 4.1e-10 39.9 0.3 7.9e-10 39.0 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KXZ47817.1 - 1.6e-09 37.9 0.4 3.1e-09 36.9 0.4 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 KXZ47817.1 - 9.7e-07 29.0 0.1 2.2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ47817.1 - 1.1e-06 28.5 0.1 2.5e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXZ47817.1 - 2.7e-05 24.8 0.4 0.00012 22.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 KXZ47817.1 - 0.00017 21.9 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ47817.1 - 0.0065 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DnaJ PF00226.31 KXZ47821.1 - 2.5e-24 85.1 0.7 4.2e-24 84.4 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 KXZ47821.1 - 1.1e-09 38.8 0.0 0.0026 18.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) TPR_1 PF00515.28 KXZ47821.1 - 1.1e-08 34.5 3.4 2e-05 24.2 0.6 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_3 PF13606.6 KXZ47821.1 - 3.5e-07 30.0 0.1 0.08 13.5 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXZ47821.1 - 5.7e-07 30.0 0.3 0.014 16.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ47821.1 - 2.3e-06 27.8 0.2 0.0079 16.5 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TPR_2 PF07719.17 KXZ47821.1 - 2.1e-05 24.3 20.3 0.00017 21.4 1.4 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat Ank PF00023.30 KXZ47821.1 - 0.00054 20.3 0.3 1.2 9.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat TPR_11 PF13414.6 KXZ47821.1 - 0.0042 16.7 1.8 0.93 9.2 0.0 3.4 3 1 1 4 4 4 1 TPR repeat DUF4440 PF14534.6 KXZ47821.1 - 0.0056 17.1 0.8 3.2 8.2 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4440) TPR_8 PF13181.6 KXZ47821.1 - 0.023 14.9 0.1 0.023 14.9 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Roughex PF06020.11 KXZ47821.1 - 0.14 11.2 5.1 0.32 10.1 5.1 1.5 1 0 0 1 1 1 0 Drosophila roughex protein TPR_7 PF13176.6 KXZ47821.1 - 1.6 9.0 4.5 52 4.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Spt20 PF12090.8 KXZ47821.1 - 1.9 8.0 7.2 4 7.0 7.2 1.5 1 0 0 1 1 1 0 Spt20 family FMO-like PF00743.19 KXZ47823.1 - 1.4e-17 63.3 0.0 1.2e-14 53.7 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXZ47823.1 - 1e-07 31.5 0.0 2.5e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ47823.1 - 5.6e-06 25.8 0.1 5.6e-06 25.8 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ47823.1 - 2.4e-05 23.6 0.0 0.00015 21.1 0.1 2.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Arm PF00514.23 KXZ47824.1 - 0.0026 17.8 14.9 0.17 12.0 0.1 6.5 7 1 0 7 7 7 2 Armadillo/beta-catenin-like repeat DRIM PF07539.12 KXZ47824.1 - 0.044 12.1 0.3 0.21 9.9 0.0 2.0 2 0 0 2 2 2 0 Down-regulated in metastasis HEAT_2 PF13646.6 KXZ47824.1 - 0.055 13.9 17.2 0.26 11.7 1.6 4.1 3 1 1 4 4 4 0 HEAT repeats FlgN PF05130.12 KXZ47824.1 - 1.6 9.3 5.6 4.4 7.8 2.7 2.6 2 1 0 2 2 2 0 FlgN protein DUF179 PF02622.15 KXZ47825.1 - 3.2e-23 82.4 0.0 5.3e-15 55.7 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized ACR, COG1678 TraD PF06412.11 KXZ47825.1 - 3.4 7.5 4.5 0.66 9.8 0.3 2.0 3 0 0 3 3 3 0 Conjugal transfer protein TraD ABC2_membrane PF01061.24 KXZ47828.1 - 1.1e-27 96.8 13.5 1.1e-27 96.8 13.5 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KXZ47828.1 - 1.1e-05 24.8 13.2 1.7e-05 24.2 13.2 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 KXZ47828.1 - 0.0031 17.4 0.5 0.012 15.5 0.5 2.0 1 0 0 1 1 1 1 CDR ABC transporter AAA_21 PF13304.6 KXZ47828.1 - 0.0038 17.1 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SpuA_C PF18033.1 KXZ47828.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 SpuA C-terminal LRR_4 PF12799.7 KXZ47829.1 - 2.2e-08 34.2 1.4 0.00016 22.0 0.1 2.2 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ47829.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 KXZ47829.1 - 0.0038 17.6 0.8 2.4 9.0 0.4 3.7 2 1 0 2 2 2 1 Leucine Rich Repeat LRRNT_2 PF08263.12 KXZ47830.1 - 0.021 15.1 0.5 0.063 13.6 0.5 1.8 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 KXZ47831.1 - 1.3e-09 38.2 3.3 4.2e-05 23.8 0.5 2.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ47831.1 - 2.3e-07 30.5 0.2 3.6e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 KXZ47831.1 - 0.004 17.5 2.0 3.7 8.5 0.1 4.0 4 1 0 4 4 4 1 Leucine Rich Repeat Peptidase_S9 PF00326.21 KXZ47833.1 - 2.6e-08 33.6 0.1 3.7e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KXZ47833.1 - 0.0008 19.0 0.9 0.0011 18.5 0.7 1.3 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KXZ47833.1 - 0.0012 19.5 0.5 0.0013 19.3 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXZ47833.1 - 0.035 13.9 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KXZ47833.1 - 0.043 13.4 0.5 0.86 9.2 0.1 2.0 1 1 1 2 2 2 0 Putative esterase Hydrolase_4 PF12146.8 KXZ47833.1 - 0.09 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KXZ47833.1 - 0.26 10.8 0.0 0.33 10.5 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 KXZ47834.1 - 2.4e-08 33.7 0.0 2.8e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXZ47834.1 - 0.0014 18.2 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXZ47834.1 - 0.059 12.6 0.0 0.087 12.1 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 PD40 PF07676.12 KXZ47835.1 - 0.00023 21.0 0.5 0.046 13.7 0.1 2.4 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat HrpB7 PF09486.10 KXZ47835.1 - 2 8.8 5.3 2.9 8.3 5.3 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) PHM7_cyt PF14703.6 KXZ47836.1 - 0.082 13.1 0.8 0.17 12.1 0.8 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Peptidase_S10 PF00450.22 KXZ47837.1 - 5.8e-77 259.9 0.0 2e-73 248.2 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase Hydrolase_4 PF12146.8 KXZ47837.1 - 0.0031 16.8 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Snapin_Pallidin PF14712.6 KXZ47838.1 - 0.0062 16.9 1.7 0.4 11.1 0.3 2.6 3 0 0 3 3 3 1 Snapin/Pallidin NUC173 PF08161.12 KXZ47838.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 2 0 0 2 2 2 0 NUC173 domain Prominin PF05478.11 KXZ47838.1 - 0.017 13.1 0.2 2 6.3 0.0 2.0 2 0 0 2 2 2 0 Prominin DNA_pol3_gamma3 PF12169.8 KXZ47838.1 - 0.03 14.2 0.4 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III GP88 PF17338.2 KXZ47838.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Gene product 88 Tweety PF04906.13 KXZ47838.1 - 0.13 10.9 0.0 0.57 8.8 0.0 1.8 2 0 0 2 2 2 0 Tweety TilS_C PF11734.8 KXZ47840.1 - 0.048 13.1 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 TilS substrate C-terminal domain TilS_C PF11734.8 KXZ47841.1 - 0.01 15.2 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 TilS substrate C-terminal domain Glyco_transf_90 PF05686.12 KXZ47842.1 - 8.4e-15 54.6 0.0 4.5e-14 52.2 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 90 CBM_20 PF00686.19 KXZ47845.1 - 1.9e-05 24.5 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain RNA_pol_Rpb4 PF03874.16 KXZ47846.1 - 3e-14 53.4 0.0 5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Imm74 PF15603.6 KXZ47846.1 - 0.089 13.0 0.2 1 9.6 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 74 Rhomboid_N PF12122.8 KXZ47846.1 - 0.11 12.7 0.1 5.9 7.1 0.0 2.5 1 1 1 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease Helicase_C PF00271.31 KXZ47847.1 - 1.8e-12 47.6 0.0 2.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 KXZ47849.1 - 1.4e-12 48.0 0.1 2.9e-12 46.9 0.1 1.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4766 PF15973.5 KXZ47849.1 - 0.0078 16.8 2.4 0.03 14.9 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4766) ResIII PF04851.15 KXZ47850.1 - 3.5e-13 49.9 0.0 5.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXZ47850.1 - 5.8e-12 46.0 0.0 1.3e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ47850.1 - 5e-11 42.7 0.0 9.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HECT PF00632.25 KXZ47851.1 - 2.1e-71 240.9 0.0 3.2e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KXZ47851.1 - 1.6e-06 27.9 8.9 0.25 11.4 0.0 6.6 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXZ47851.1 - 0.018 15.2 4.7 9.3 6.8 0.2 4.3 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 KXZ47851.1 - 0.029 14.8 0.1 0.029 14.8 0.1 4.8 5 0 0 5 5 5 0 HEAT repeats MMS19_N PF14500.6 KXZ47851.1 - 0.28 10.7 0.4 1.4 8.5 0.2 2.1 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II UNC45-central PF11701.8 KXZ47851.1 - 0.54 10.2 3.3 0.78 9.7 0.1 2.7 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF679 PF05078.12 KXZ47852.1 - 3.4e-30 105.2 5.6 4.1e-30 104.9 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF679) DUF998 PF06197.13 KXZ47852.1 - 0.038 13.6 0.6 0.065 12.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF998) EamA PF00892.20 KXZ47852.1 - 3.4 7.9 7.5 0.81 9.9 1.0 2.1 2 0 0 2 2 2 0 EamA-like transporter family RINGv PF12906.7 KXZ47853.1 - 1.2e-06 28.5 4.9 3.3e-06 27.1 4.9 1.8 1 1 0 1 1 1 1 RING-variant domain DUF587 PF04532.12 KXZ47853.1 - 0.35 10.1 3.9 0.62 9.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF587) zf-RING_2 PF13639.6 KXZ47853.1 - 1.2 9.5 12.1 4.1 7.8 12.1 1.9 1 1 0 1 1 1 0 Ring finger domain Borrelia_P83 PF05262.11 KXZ47853.1 - 1.7 7.1 3.1 2.5 6.5 3.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein EXOSC1 PF10447.9 KXZ47854.1 - 5.4e-17 62.4 1.9 1e-14 55.1 0.3 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KXZ47854.1 - 2.3e-08 33.7 2.9 4.1e-08 32.9 0.5 2.4 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region Mito_carr PF00153.27 KXZ47855.1 - 1.8e-35 120.7 9.3 1.2e-15 57.2 0.2 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Popeye PF04831.13 KXZ47856.1 - 0.013 15.6 0.1 0.014 15.6 0.1 1.0 1 0 0 1 1 1 0 Popeye protein conserved region DAGK_acc PF00609.19 KXZ47857.1 - 1.1e-37 129.8 0.0 1.1e-16 61.6 0.0 3.1 2 1 0 2 2 2 2 Diacylglycerol kinase accessory domain DNA_primase_S PF01896.19 KXZ47858.1 - 2e-49 168.1 0.0 2.5e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 DNA primase small subunit ABM PF03992.16 KXZ47859.1 - 1.5e-17 63.5 0.2 2e-17 63.1 0.2 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.6 KXZ47859.1 - 0.073 12.5 2.3 0.11 11.9 2.3 1.4 1 1 0 1 1 1 0 Haem-containing dehydratase UvrD-helicase PF00580.21 KXZ47860.1 - 1.6e-41 142.9 0.0 1.1e-38 133.6 0.0 3.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KXZ47860.1 - 2e-36 126.1 0.0 2.7e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXZ47860.1 - 2.1e-23 83.3 0.0 1e-20 74.5 0.0 3.9 3 1 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 KXZ47860.1 - 1e-09 38.1 0.1 4.2e-09 36.1 0.1 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXZ47860.1 - 0.02 14.7 0.0 7 6.3 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Ank_2 PF12796.7 KXZ47862.1 - 5.1e-10 39.8 0.1 0.022 15.3 0.0 5.2 3 2 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47862.1 - 1.2e-08 35.3 7.6 2.9 8.6 0.0 9.0 6 3 3 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ47862.1 - 0.034 14.7 11.0 98 4.0 0.0 8.5 10 1 1 11 11 11 0 Ankyrin repeat DUF4407 PF14362.6 KXZ47864.1 - 0.049 13.0 8.3 0.09 12.1 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KXZ47864.1 - 0.05 12.5 6.6 0.081 11.8 6.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 KXZ47864.1 - 0.062 13.9 4.0 1.2 9.8 0.0 2.2 1 1 0 2 2 2 0 Initiation control protein YabA PspA_IM30 PF04012.12 KXZ47864.1 - 0.085 12.4 12.5 0.16 11.5 12.5 1.4 1 0 0 1 1 1 0 PspA/IM30 family EcKinase PF02958.20 KXZ47864.1 - 0.24 10.7 1.9 0.34 10.2 1.9 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase CorA PF01544.18 KXZ47864.1 - 0.25 10.6 6.2 0.4 9.9 6.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DHR10 PF18595.1 KXZ47864.1 - 0.78 9.8 15.7 0.88 9.6 5.8 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain PRKG1_interact PF15898.5 KXZ47864.1 - 0.84 10.6 8.0 1.5 9.8 8.0 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain HAUS6_N PF14661.6 KXZ47864.1 - 1.6 8.3 6.6 2.7 7.5 6.6 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TSNAXIP1_N PF15739.5 KXZ47864.1 - 1.6 9.1 6.7 0.54 10.7 2.0 2.1 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DivIVA PF05103.13 KXZ47864.1 - 3.1 7.9 7.8 5.4 7.1 7.8 1.3 1 0 0 1 1 1 0 DivIVA protein CENP-H PF05837.12 KXZ47864.1 - 3.6 8.0 12.0 7.8 7.0 0.5 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KXZ47864.1 - 8.5 6.9 11.8 73 3.9 11.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DNA_pol_A PF00476.20 KXZ47865.1 - 3.3e-78 263.4 0.0 1.1e-77 261.6 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family A Guanylate_cyc PF00211.20 KXZ47866.1 - 3.8e-10 39.7 0.0 0.00025 20.7 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ47867.1 - 1.2e-10 41.4 0.0 4.3e-05 23.2 0.0 2.5 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ47868.1 - 5.2e-13 49.0 0.0 2.2e-07 30.7 0.0 2.7 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CcmD PF04995.14 KXZ47868.1 - 0.11 12.6 3.2 0.33 11.1 3.2 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Syndecan PF01034.20 KXZ47868.1 - 0.79 9.7 2.5 2.8 7.9 2.5 1.9 1 0 0 1 1 1 0 Syndecan domain Amidohydro_3 PF07969.11 KXZ47869.1 - 3.1e-70 238.0 16.6 2.5e-63 215.2 13.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXZ47869.1 - 6.5e-09 35.6 0.1 0.0016 17.8 0.0 3.4 3 0 0 3 3 3 3 Amidohydrolase family RNA_pol_A_bac PF01000.26 KXZ47870.1 - 5.6e-25 87.9 0.0 1.4e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXZ47870.1 - 1.8e-24 85.0 0.0 2.7e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Guanylate_cyc PF00211.20 KXZ47871.1 - 2.6e-18 66.3 0.0 2.8e-11 43.4 0.0 2.8 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Peptidase_M43 PF05572.13 KXZ47872.1 - 0.00081 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A DUF3459 PF11941.8 KXZ47873.1 - 0.052 13.9 0.1 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) Myc_N PF01056.18 KXZ47874.1 - 6.8 6.5 10.6 47 3.7 10.6 2.2 1 1 0 1 1 1 0 Myc amino-terminal region tRNA-synt_1c PF00749.21 KXZ47875.1 - 2e-103 345.6 0.0 2.5e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HTH_Tnp_4 PF13613.6 KXZ47876.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease TSKS PF15358.6 KXZ47877.1 - 0.01 14.2 0.2 0.01 14.2 0.2 2.1 2 0 0 2 2 2 0 Testis-specific serine kinase substrate HGWP PF03578.15 KXZ47877.1 - 0.015 14.8 0.2 9.7 5.8 0.0 3.0 2 0 0 2 2 2 0 HGWP repeat DUF5323 PF17257.2 KXZ47877.1 - 0.5 10.3 5.7 6.7 6.7 0.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Peptidase_C53 PF05550.11 KXZ47879.1 - 0.09 12.5 0.4 0.15 11.8 0.1 1.5 2 0 0 2 2 2 0 Pestivirus Npro endopeptidase C53 G8 PF10162.9 KXZ47880.1 - 8.3e-57 190.6 0.0 3.3e-31 107.9 0.0 2.8 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 KXZ47880.1 - 5.4e-50 167.4 55.1 6.1e-11 42.3 0.1 11.6 11 0 0 11 11 11 8 IPT/TIG domain PA14 PF07691.12 KXZ47880.1 - 1.7e-09 37.6 0.2 0.00089 19.1 0.1 2.6 2 0 0 2 2 2 2 PA14 domain GLEYA PF10528.9 KXZ47880.1 - 1.9e-05 25.0 3.8 0.0035 17.7 0.1 3.2 2 0 0 2 2 2 2 GLEYA domain Beta_helix PF13229.6 KXZ47880.1 - 0.00011 22.1 12.1 0.002 18.0 2.8 3.7 2 1 0 2 2 2 2 Right handed beta helix region G8 PF10162.9 KXZ47882.1 - 1.3e-20 73.7 0.0 2.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 G8 domain G8 PF10162.9 KXZ47884.1 - 5.3e-57 191.2 0.0 3.8e-31 107.7 0.0 3.2 3 0 0 3 3 3 2 G8 domain TIG PF01833.24 KXZ47884.1 - 2.1e-52 175.1 57.9 4.6e-12 45.8 0.2 11.9 12 0 0 12 12 12 8 IPT/TIG domain PA14 PF07691.12 KXZ47884.1 - 1.3e-08 34.8 0.2 0.0012 18.7 0.1 2.6 2 0 0 2 2 2 2 PA14 domain GLEYA PF10528.9 KXZ47884.1 - 6e-05 23.4 5.2 0.011 16.1 0.1 3.1 2 0 0 2 2 2 2 GLEYA domain Beta_helix PF13229.6 KXZ47884.1 - 0.00017 21.4 11.3 0.0018 18.1 3.3 3.6 2 1 1 3 3 3 2 Right handed beta helix region TIG PF01833.24 KXZ47885.1 - 3.9e-54 180.7 80.7 1.7e-11 44.0 1.4 13.2 13 1 0 13 13 13 9 IPT/TIG domain G8 PF10162.9 KXZ47885.1 - 5.8e-54 181.4 0.0 4.2e-29 101.1 0.0 3.0 2 0 0 2 2 2 2 G8 domain PA14 PF07691.12 KXZ47885.1 - 1.2e-05 25.1 0.4 0.012 15.5 0.1 2.6 2 0 0 2 2 2 2 PA14 domain GLEYA PF10528.9 KXZ47885.1 - 3.1e-05 24.3 3.1 0.026 14.9 0.1 3.4 2 0 0 2 2 2 2 GLEYA domain Beta_helix PF13229.6 KXZ47885.1 - 0.027 14.3 21.1 0.017 14.9 4.7 3.7 2 1 1 3 3 3 0 Right handed beta helix region DSPc PF00782.20 KXZ47886.1 - 1.2e-22 80.1 0.0 6.1e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain HAD_2 PF13419.6 KXZ47886.1 - 1.9e-16 60.7 0.0 2.5e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ47886.1 - 6.7e-09 36.3 0.5 6.4e-08 33.1 0.5 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ47886.1 - 0.00028 20.9 0.1 0.0006 19.8 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Zn_ribbon_SprT PF17283.2 KXZ47886.1 - 0.037 13.9 0.1 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF1356 PF07092.12 KXZ47887.1 - 0.16 11.2 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) UvrD-helicase PF00580.21 KXZ47888.1 - 8.2e-60 203.0 0.0 1.1e-58 199.2 0.0 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KXZ47888.1 - 1.2e-46 159.8 0.0 2e-26 93.2 0.0 3.2 3 0 0 3 3 3 3 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXZ47888.1 - 2.9e-34 118.5 0.0 1.1e-33 116.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXZ47888.1 - 1.8e-09 37.2 0.7 7.7e-09 35.2 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXZ47888.1 - 1.6e-07 31.3 0.0 0.00028 20.7 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KXZ47888.1 - 7e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KXZ47888.1 - 0.091 12.4 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KXZ47888.1 - 0.24 11.4 0.0 0.5 10.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Guanylate_cyc PF00211.20 KXZ47889.1 - 2.4e-43 147.9 0.0 3.7e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RVT_1 PF00078.27 KXZ47890.1 - 0.047 13.2 0.2 0.19 11.2 0.2 2.0 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Guanylate_cyc PF00211.20 KXZ47891.1 - 3e-52 176.9 0.0 4.1e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KXZ47893.1 - 7.7e-50 169.6 0.0 1.4e-39 136.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47893.1 - 1.8e-36 125.8 0.0 1.3e-35 123.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ47893.1 - 3.6e-05 22.7 0.1 6.5e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase CAMSAP_CC1 PF17095.5 KXZ47893.1 - 0.021 14.7 0.5 0.063 13.1 0.5 1.7 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Kdo PF06293.14 KXZ47893.1 - 0.059 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ47893.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.9 4 0 0 4 4 4 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ47894.1 - 2e-14 53.5 0.0 4.7e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47894.1 - 3.1e-14 53.0 0.0 1.4e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47895.1 - 1.3e-10 41.1 0.0 1.4e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ47895.1 - 3.3e-09 36.5 0.0 3.6e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KXZ47897.1 - 5.2e-30 104.7 0.0 4.4e-18 65.6 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47897.1 - 4.2e-28 98.3 0.0 1.2e-14 54.3 0.0 3.0 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KXZ47897.1 - 0.047 13.6 0.1 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyoxalase PF00903.25 KXZ47898.1 - 8.4e-09 35.7 0.2 0.0011 19.2 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXZ47898.1 - 2.4e-07 31.0 0.1 0.015 15.5 0.0 3.0 2 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KXZ47898.1 - 3.9e-06 27.1 1.2 0.00085 19.5 0.0 3.2 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KXZ47898.1 - 0.31 11.1 1.3 10 6.2 0.2 3.2 2 1 0 2 2 2 0 Glyoxalase-like domain UPF0061 PF02696.14 KXZ47900.1 - 2.6e-115 385.9 0.0 1.1e-106 357.4 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family RE_XamI PF09572.10 KXZ47900.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 XamI restriction endonuclease Hormone_6 PF00236.18 KXZ47900.1 - 0.048 13.6 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Glycoprotein hormone GREB1 PF15782.5 KXZ47901.1 - 5.5 4.0 23.1 6.5 3.7 23.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nucleo_P87 PF07267.11 KXZ47901.1 - 7.8 5.2 16.1 13 4.5 16.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_S6 PF01250.17 KXZ47902.1 - 7e-17 61.5 0.0 1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 AFG1_ATPase PF03969.16 KXZ47903.1 - 8.5e-40 136.8 0.0 7.4e-39 133.7 0.0 2.0 1 1 0 1 1 1 1 AFG1-like ATPase Auxin_inducible PF02519.14 KXZ47903.1 - 0.051 13.8 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Auxin responsive protein LRR_4 PF12799.7 KXZ47904.1 - 0.00031 21.1 3.3 18 6.0 0.0 6.2 5 3 1 6 6 6 1 Leucine Rich repeats (2 copies) HTH_Tnp_ISL3 PF13542.6 KXZ47904.1 - 0.17 11.4 0.0 0.61 9.5 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 LRR_6 PF13516.6 KXZ47904.1 - 0.26 11.4 8.0 2.5 8.4 0.1 5.2 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 KXZ47904.1 - 2 9.3 4.4 31 5.6 0.1 3.9 4 1 0 4 4 4 0 Leucine Rich Repeat MSA-2c PF12238.8 KXZ47904.1 - 2.6 8.0 7.6 4.3 7.3 7.6 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c CFEM PF05730.11 KXZ47905.1 - 0.18 12.0 1.9 0.41 10.8 1.9 1.5 1 0 0 1 1 1 0 CFEM domain zf-MYND PF01753.18 KXZ47906.1 - 2.5e-10 40.3 11.2 4.7e-10 39.4 11.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ47906.1 - 0.85 10.0 8.3 1.8 8.9 8.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXZ47908.1 - 1e-11 44.7 10.0 1.6e-11 44.1 10.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ47908.1 - 0.13 12.6 7.0 0.21 12.0 7.0 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXZ47909.1 - 2e-10 40.6 8.9 4.6e-10 39.4 8.9 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ47909.1 - 1.1 9.6 4.9 2.7 8.4 4.9 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DSPc PF00782.20 KXZ47911.1 - 1.9e-25 89.2 0.0 2.5e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain FHA PF00498.26 KXZ47911.1 - 7.3e-15 55.1 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXZ47911.1 - 8.7e-10 38.8 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Y_phosphatase PF00102.27 KXZ47911.1 - 0.001 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXZ47911.1 - 0.016 15.3 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate UvrD-helicase PF00580.21 KXZ47912.1 - 0.0027 17.3 7.9 0.0033 17.0 7.9 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain TFIIA PF03153.13 KXZ47912.1 - 0.0047 17.0 12.3 0.0047 17.0 12.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BBP1_C PF15272.6 KXZ47912.1 - 0.17 11.7 20.3 0.21 11.4 16.8 2.5 1 1 2 3 3 3 0 Spindle pole body component BBP1, C-terminal Golgin_A5 PF09787.9 KXZ47912.1 - 0.23 10.9 25.5 0.43 10.0 25.5 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 DSPc PF00782.20 KXZ47912.1 - 0.56 10.0 4.4 4.8 7.0 0.0 3.3 3 1 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Ribosomal_L38e PF01781.18 KXZ47912.1 - 0.75 9.9 5.7 10 6.3 0.2 3.6 2 1 1 3 3 3 0 Ribosomal L38e protein family Ago_PAZ PF18309.1 KXZ47912.1 - 1.3 9.7 5.7 11 6.7 1.1 3.0 2 1 1 3 3 3 0 Argonaute PAZ domain CadC_C1 PF18500.1 KXZ47912.1 - 1.4 9.1 6.0 17 5.5 0.5 2.7 1 1 2 3 3 3 0 CadC C-terminal domain 1 LMBR1 PF04791.16 KXZ47912.1 - 2.1 7.2 7.2 2.4 7.0 7.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Asp-B-Hydro_N PF05279.11 KXZ47912.1 - 3.4 7.7 12.7 5.1 7.1 12.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Acetate_kinase PF00871.17 KXZ47912.1 - 4.3 5.9 6.3 4.2 5.9 2.2 2.0 1 1 1 2 2 2 0 Acetokinase family FAM110_N PF14161.6 KXZ47913.1 - 0.095 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Centrosome-associated N terminus Pkinase_Tyr PF07714.17 KXZ47914.1 - 2.4e-48 164.7 0.0 3.8e-39 134.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47914.1 - 1e-37 130.0 0.0 1.2e-36 126.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain CHASE PF03924.13 KXZ47914.1 - 1.3e-10 41.5 0.0 3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 CHASE domain DUF4775 PF16001.5 KXZ47914.1 - 0.6 9.5 3.2 1.4 8.3 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) NYN PF01936.18 KXZ47915.1 - 1.5e-12 48.3 0.0 1.8e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 NYN domain GRDP-like PF07173.12 KXZ47916.1 - 8.4e-13 49.2 0.3 2e-09 38.3 0.0 2.2 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like GRDP-like PF07173.12 KXZ47917.1 - 4.5e-11 43.6 0.3 2.4e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like SNF2_N PF00176.23 KXZ47920.1 - 1.4e-50 172.0 0.0 1.9e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ47920.1 - 1.4e-17 64.0 0.0 2.7e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ47920.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 KXZ47920.1 - 0.02 14.3 13.2 0.41 10.0 6.4 2.2 2 0 0 2 2 2 0 SDA1 DUF1952 PF09189.10 KXZ47920.1 - 0.029 14.2 6.1 2.2 8.2 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) YL1 PF05764.13 KXZ47920.1 - 0.075 13.1 14.9 1.6 8.8 0.6 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Barttin PF15462.6 KXZ47920.1 - 0.59 9.9 5.5 0.15 11.8 1.1 2.3 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) THF_DHG_CYH_C PF02882.19 KXZ47921.1 - 2.6e-39 134.1 3.2 2.9e-20 72.2 0.3 3.2 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KXZ47921.1 - 5.4e-24 84.7 0.0 8.7e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Adeno_PIX PF03955.14 KXZ47921.1 - 2.4 8.4 10.5 7.5 6.8 0.5 2.5 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) PNP_UDP_1 PF01048.20 KXZ47923.1 - 2.2e-22 79.5 0.9 3.3e-22 78.9 0.9 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily Guanylate_cyc PF00211.20 KXZ47924.1 - 1.1e-56 191.4 0.0 1.6e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 KXZ47924.1 - 0.027 14.7 0.1 0.13 12.5 0.1 2.2 1 0 0 1 1 1 0 PAS fold YppG PF14179.6 KXZ47927.1 - 0.051 14.3 0.9 0.051 14.3 0.9 2.1 2 0 0 2 2 2 0 YppG-like protein CUB PF00431.20 KXZ47928.1 - 4.7e-09 36.6 0.0 0.00053 20.3 0.0 2.7 3 0 0 3 3 3 2 CUB domain Glyco_hydro_9 PF00759.19 KXZ47929.1 - 1.3e-19 70.9 0.0 1.5e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KXZ47930.1 - 2.7e-30 106.1 2.9 3.4e-30 105.8 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KXZ47931.1 - 1e-12 48.3 2.1 2.8e-11 43.5 1.6 1.9 1 1 1 2 2 2 2 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KXZ47932.1 - 1.8e-20 73.8 0.0 4e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 VCBS PF13517.6 KXZ47932.1 - 0.0016 19.0 0.5 3.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PduV-EutP PF10662.9 KXZ47932.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ank_2 PF12796.7 KXZ47933.1 - 2.4e-05 24.8 0.1 0.45 11.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47933.1 - 0.00035 21.1 1.0 0.065 13.8 0.0 4.3 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ47933.1 - 1.4 9.3 4.2 23 5.5 0.0 3.9 2 2 2 4 4 4 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ47934.1 - 0.00012 22.6 3.3 0.012 16.2 0.0 4.4 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47934.1 - 0.00046 20.7 0.2 0.24 12.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ47934.1 - 0.046 14.3 3.0 16 6.5 0.0 4.9 6 0 0 6 6 6 0 Ankyrin repeat ATX_III PF08098.11 KXZ47934.1 - 1.6 8.8 8.2 7.9 6.6 0.5 3.9 3 0 0 3 3 3 0 Anemonia sulcata toxin III family Pkinase_Tyr PF07714.17 KXZ47935.1 - 6.8e-29 100.9 0.0 4.4e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47935.1 - 1.6e-23 83.4 0.0 1e-22 80.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ47935.1 - 0.00053 18.9 0.0 0.00082 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ47935.1 - 0.0095 15.9 0.8 0.028 14.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family GAF_2 PF13185.6 KXZ47936.1 - 0.04 14.2 3.4 0.11 12.8 0.6 2.9 2 1 0 2 2 2 0 GAF domain Ank_2 PF12796.7 KXZ47937.1 - 0.014 16.0 3.6 5.4 7.7 0.7 3.6 2 2 3 5 5 5 0 Ankyrin repeats (3 copies) HTH_39 PF14090.6 KXZ47937.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Ank_2 PF12796.7 KXZ47939.1 - 8.4e-06 26.3 2.1 0.74 10.4 0.2 4.4 2 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47939.1 - 0.00048 20.6 3.1 0.33 11.6 0.0 5.0 6 2 1 7 7 7 2 Ankyrin repeats (many copies) Thioredoxin PF00085.20 KXZ47940.1 - 1.8e-26 92.1 0.1 2.1e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KXZ47940.1 - 5.1e-08 33.0 0.1 6.8e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXZ47940.1 - 3.9e-06 27.3 0.1 8e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ47940.1 - 0.0001 22.6 0.1 0.069 13.5 0.0 2.5 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KXZ47940.1 - 0.00012 21.9 0.1 0.00018 21.4 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ47940.1 - 0.00094 18.9 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 KXZ47940.1 - 0.062 12.7 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 KXZ47940.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin DUF2301 PF10063.9 KXZ47942.1 - 9e-52 175.1 0.3 1.2e-51 174.7 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized integral membrane protein (DUF2301) Hormone_recep PF00104.30 KXZ47942.1 - 0.15 11.6 0.2 0.26 10.8 0.2 1.3 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor DUF4574 PF15141.6 KXZ47942.1 - 1.1 9.2 4.0 3.2 7.7 0.7 2.6 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 WRKY PF03106.15 KXZ47943.1 - 5.3e-47 157.9 21.6 1.6e-25 89.1 5.6 2.6 3 0 0 3 3 3 2 WRKY DNA -binding domain FLYWCH PF04500.16 KXZ47943.1 - 0.055 13.6 2.9 4.2 7.6 0.4 2.5 2 0 0 2 2 2 0 FLYWCH zinc finger domain KI67R PF08065.12 KXZ47943.1 - 0.18 12.3 14.0 1.8 9.1 8.5 2.5 2 0 0 2 2 2 0 KI67R (NUC007) repeat Suf PF05843.14 KXZ47943.1 - 0.43 10.5 12.0 0.22 11.5 9.1 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 KXZ47943.1 - 6 5.7 11.0 8.8 5.2 11.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Biotin_lipoyl PF00364.22 KXZ47944.1 - 2.6e-10 40.0 0.0 4.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 KXZ47944.1 - 0.00031 20.0 0.0 0.00043 19.6 0.0 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 KXZ47944.1 - 0.007 16.2 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like SAP130_C PF16014.5 KXZ47944.1 - 8.6 5.3 13.1 11 5.0 13.1 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Ank_2 PF12796.7 KXZ47945.1 - 2.9e-08 34.2 1.5 0.33 11.6 0.0 5.0 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47945.1 - 0.0056 17.2 6.8 24 5.7 0.0 6.2 4 3 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ47946.1 - 3.6e-08 33.9 2.9 0.0066 17.0 0.6 4.2 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ47946.1 - 1.2e-06 28.9 5.5 0.0085 16.7 0.0 5.9 5 2 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ47946.1 - 0.097 13.3 5.3 31 5.6 0.0 6.2 7 1 0 7 7 7 0 Ankyrin repeat Bromodomain PF00439.25 KXZ47947.1 - 5.9e-15 55.1 0.1 9.9e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXZ47947.1 - 1.1e-09 38.5 0.1 2.5e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ47947.1 - 2e-08 34.2 0.1 4.1e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ47947.1 - 3.9e-06 27.2 0.1 8.6e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ47947.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein SRCR PF00530.18 KXZ47948.1 - 1.8e-19 70.1 0.2 6e-19 68.4 0.2 2.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain TRP PF06011.12 KXZ47948.1 - 1e-06 27.8 0.3 1.7e-06 27.1 0.3 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel SRCR_2 PF15494.6 KXZ47948.1 - 0.0072 16.8 0.0 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Spt20 PF12090.8 KXZ47948.1 - 0.52 9.9 0.7 0.8 9.3 0.7 1.1 1 0 0 1 1 1 0 Spt20 family CENP-F_leu_zip PF10473.9 KXZ47950.1 - 0.0082 16.2 13.7 0.0082 16.2 13.7 7.0 2 2 2 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cytochrom_B562 PF07361.11 KXZ47950.1 - 0.016 15.9 7.1 0.016 15.9 7.1 7.8 3 2 2 6 6 6 0 Cytochrome b562 FlaC_arch PF05377.11 KXZ47950.1 - 0.14 12.5 19.6 12 6.4 0.3 7.5 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) DASH_Dad4 PF08650.10 KXZ47950.1 - 2.9 7.9 5.9 1 9.4 0.4 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF2120 PF09893.9 KXZ47950.1 - 5.9 7.0 5.7 1.8 8.6 0.4 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) BLOC1_2 PF10046.9 KXZ47950.1 - 8.3 6.8 48.0 0.98 9.8 1.5 7.6 4 4 3 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apolipoprotein PF01442.18 KXZ47953.1 - 0.12 12.2 4.9 8.2 6.2 0.3 4.3 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain Spidroin_N PF16763.5 KXZ47953.1 - 0.18 11.8 0.7 0.65 10.0 0.7 2.0 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF4131 PF13567.6 KXZ47953.1 - 0.78 9.4 4.5 2.1 8.0 4.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) eIF-5a PF01287.20 KXZ47954.1 - 0.0006 19.9 0.0 0.00075 19.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RVT_2 PF07727.14 KXZ47955.1 - 5.5e-27 95.0 0.0 6.1e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NIF PF03031.18 KXZ47957.1 - 5.5e-08 32.7 0.0 8.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KXZ47957.1 - 7.5e-07 29.0 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXZ47957.1 - 0.0031 17.8 0.0 0.0053 17.1 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF5600 PF18150.1 KXZ47958.1 - 0.012 16.2 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5600) GRP PF07172.11 KXZ47960.1 - 0.06 14.0 12.8 0.092 13.4 10.1 2.3 2 0 0 2 2 2 0 Glycine rich protein family PP2C PF00481.21 KXZ47961.1 - 4.6e-24 85.4 0.8 1.6e-06 27.9 0.0 4.1 3 1 1 4 4 4 4 Protein phosphatase 2C Pkinase PF00069.25 KXZ47962.1 - 9e-30 103.9 0.0 1.3e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47962.1 - 1.8e-25 89.7 0.0 7e-25 87.8 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXZ47962.1 - 0.0038 17.2 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ47962.1 - 0.19 10.6 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain HAUS6_N PF14661.6 KXZ47963.1 - 0.56 9.7 6.9 1.1 8.7 6.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Glutaredoxin PF00462.24 KXZ47964.1 - 3e-45 152.3 0.0 8.5e-20 70.7 0.0 3.6 3 1 1 4 4 4 3 Glutaredoxin Thioredoxin PF00085.20 KXZ47964.1 - 2.4e-16 59.6 0.0 4.8e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ47964.1 - 1.2e-07 32.1 0.1 3e-06 27.6 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KXZ47964.1 - 8.6e-07 28.9 0.0 3.4e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family GST_N_3 PF13417.6 KXZ47964.1 - 1e-06 29.1 0.0 0.0024 18.2 0.0 3.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 KXZ47964.1 - 5.3e-06 26.5 0.0 0.03 14.5 0.0 2.4 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein Thioredoxin_7 PF13899.6 KXZ47964.1 - 1.8e-05 24.8 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KXZ47964.1 - 0.0001 22.5 0.0 0.0025 18.1 0.0 2.5 2 1 1 3 3 2 1 Thioredoxin-like Redoxin PF08534.10 KXZ47964.1 - 0.00028 20.6 0.1 0.00085 19.1 0.0 1.8 2 1 0 2 2 2 1 Redoxin Thioredoxin_3 PF13192.6 KXZ47964.1 - 0.00067 19.7 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.11 KXZ47964.1 - 0.0076 16.2 0.1 0.032 14.2 0.0 2.1 3 0 0 3 3 2 1 Hydrogenase-1 expression protein HyaE DIM1 PF02966.16 KXZ47964.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 DEC-1_N PF04625.13 KXZ47964.1 - 0.14 11.2 5.6 0.2 10.7 5.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MciZ PF13072.6 KXZ47964.1 - 0.16 11.8 0.1 12 5.8 0.1 2.4 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ CAP_N PF01213.19 KXZ47964.1 - 3 7.2 4.0 4.6 6.6 4.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase_Tyr PF07714.17 KXZ47965.1 - 2.4e-32 112.3 0.0 5.9e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ47965.1 - 5.2e-28 98.1 0.0 4.7e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain SDA1 PF05285.12 KXZ47966.1 - 0.49 9.8 12.7 0.74 9.2 12.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KXZ47967.1 - 0.14 10.4 1.1 0.22 9.8 1.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 KXZ47967.1 - 0.17 12.0 4.2 0.3 11.2 4.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SRCR PF00530.18 KXZ47968.1 - 2e-22 79.6 0.2 5e-09 36.6 0.0 3.5 2 2 1 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ47968.1 - 4.3e-05 24.0 0.0 0.52 10.9 0.0 3.1 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Ntox44 PF15607.6 KXZ47968.1 - 0.00028 21.1 0.4 1 9.7 0.1 2.4 1 1 1 2 2 2 2 Bacterial toxin 44 MgpC PF05220.12 KXZ47968.1 - 0.012 14.9 1.7 0.022 14.1 1.6 1.4 1 1 0 1 1 1 0 MgpC protein precursor DUF4560 PF15118.6 KXZ47968.1 - 0.13 12.2 0.1 28 4.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4560) PHD_3 PF13922.6 KXZ47968.1 - 5.2 7.5 9.0 10 6.6 0.1 3.8 3 1 1 4 4 4 0 PHD domain of transcriptional enhancer, Asx SRCR PF00530.18 KXZ47970.1 - 2.6e-19 69.6 1.9 1.6e-08 35.0 0.3 2.5 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ47970.1 - 0.00048 20.6 1.4 0.4 11.3 0.6 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KXZ47971.1 - 3.4e-30 104.5 3.8 3.4e-15 56.3 0.8 2.2 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ47971.1 - 6e-05 23.5 0.3 0.22 12.1 0.1 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain DUF5516 PF17637.2 KXZ47971.1 - 0.078 12.7 1.0 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5516) SRCR PF00530.18 KXZ47972.1 - 4.5e-47 158.7 15.1 8.5e-15 55.1 1.0 4.5 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ47972.1 - 8.1e-07 29.5 11.2 1.1 9.8 0.4 4.6 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain FAP206 PF12018.8 KXZ47973.1 - 7.2e-18 65.1 0.0 1.8e-17 63.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function Peptidase_M22 PF00814.25 KXZ47973.1 - 0.0039 16.9 0.6 0.038 13.7 0.0 2.3 2 1 0 2 2 2 1 Glycoprotease family UPF0193 PF05250.11 KXZ47974.1 - 3.1e-15 56.6 3.6 4e-15 56.2 3.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Ferritin PF00210.24 KXZ47974.1 - 0.094 12.6 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Ferritin-like domain Aminotran_1_2 PF00155.21 KXZ47975.1 - 3.7e-53 181.0 0.0 4.7e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXZ47975.1 - 0.00055 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KXZ47975.1 - 0.009 14.8 0.0 0.018 13.8 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Ins_P5_2-kin PF06090.12 KXZ47977.1 - 3.5e-44 151.6 0.0 5.8e-44 150.9 0.0 1.3 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Pkinase PF00069.25 KXZ47978.1 - 2.8e-30 105.6 0.0 1.9e-28 99.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47978.1 - 1.1e-26 93.7 0.0 1.1e-24 87.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ47978.1 - 0.00034 20.6 0.1 0.00062 19.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Bromo_coat PF01318.18 KXZ47978.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Bromovirus coat protein Pkinase_fungal PF17667.1 KXZ47978.1 - 0.097 11.4 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ47979.1 - 4e-31 108.3 0.0 3.1e-28 98.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47979.1 - 1.9e-27 96.2 0.0 8e-25 87.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ47979.1 - 0.00061 19.8 0.0 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ47979.1 - 0.087 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ47980.1 - 0.0038 16.6 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase eIF3g PF12353.8 KXZ47981.1 - 0.21 12.0 0.0 0.47 10.9 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Chloroa_b-bind PF00504.21 KXZ47982.1 - 3.9e-52 177.0 0.0 5.4e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein FAST_1 PF06743.15 KXZ47984.1 - 1.8e-29 101.5 0.7 1.2e-05 25.1 0.0 7.6 3 2 6 9 9 9 8 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KXZ47984.1 - 1.6e-06 28.1 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 KXZ47984.1 - 0.007 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 Pkinase PF00069.25 KXZ47985.1 - 8.8e-17 61.3 0.0 1.1e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ47985.1 - 9.7e-15 54.5 0.0 2.5e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ47985.1 - 0.036 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ47985.1 - 0.037 13.3 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Bindin PF02084.15 KXZ47985.1 - 8.5 6.6 11.5 2.1 8.6 6.7 2.0 2 0 0 2 2 2 0 Bindin Myelin_PLP PF01275.19 KXZ47986.1 - 3.5e-05 23.8 0.1 4.8e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) NOT2_3_5 PF04153.18 KXZ47988.1 - 1.9e-34 118.6 5.0 2.6e-34 118.1 5.0 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family WD40 PF00400.32 KXZ47989.1 - 7.3e-42 140.6 25.0 1.5e-07 31.9 1.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ47989.1 - 1.1e-13 51.2 0.7 0.0013 19.0 0.0 5.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Cep57_CLD_2 PF14197.6 KXZ47989.1 - 0.007 16.4 7.6 0.23 11.6 2.2 2.7 3 0 0 3 3 3 2 Centrosome localisation domain of PPC89 YabA PF06156.13 KXZ47989.1 - 0.04 14.6 0.5 0.9 10.2 0.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Sec34 PF04136.15 KXZ47989.1 - 0.049 13.5 0.5 0.097 12.6 0.5 1.5 1 0 0 1 1 1 0 Sec34-like family Tho2 PF11262.8 KXZ47989.1 - 0.072 12.3 2.6 0.11 11.7 2.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PALB2_WD40 PF16756.5 KXZ47989.1 - 0.093 11.6 1.9 1.8 7.4 0.2 2.3 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RmuC PF02646.16 KXZ47989.1 - 0.11 11.6 0.7 0.24 10.5 0.4 1.6 1 1 0 1 1 1 0 RmuC family Nup160 PF11715.8 KXZ47989.1 - 0.17 10.5 2.5 12 4.3 0.1 3.4 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXZ47989.1 - 0.23 10.4 5.0 12 4.7 0.1 3.6 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IR1-M PF12185.8 KXZ47989.1 - 0.3 11.1 1.6 0.66 10.0 1.6 1.6 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DUF3138 PF11336.8 KXZ47990.1 - 0.27 9.8 0.7 0.36 9.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Arf PF00025.21 KXZ47991.1 - 7.2e-50 168.8 0.0 8.8e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXZ47991.1 - 1.5e-10 41.4 0.0 2.4e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ47991.1 - 5.4e-10 39.1 0.0 7.7e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXZ47991.1 - 2.1e-09 37.0 0.0 3e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXZ47991.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXZ47991.1 - 1.1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXZ47991.1 - 0.00028 20.9 0.0 0.0004 20.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXZ47991.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KXZ47991.1 - 0.1 12.1 0.1 0.26 10.8 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 KXZ47991.1 - 0.11 12.9 0.0 13 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 KXZ47991.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Dus PF01207.17 KXZ47992.1 - 1.1e-44 152.8 0.0 1.8e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KXZ47992.1 - 1.2e-08 34.6 9.8 8.2e-08 31.9 2.0 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 KXZ47992.1 - 8.4e-08 31.9 4.7 0.00012 21.9 0.7 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXZ47992.1 - 5.3e-06 26.3 9.7 4.5e-05 23.3 3.9 2.7 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KXZ47992.1 - 0.0024 18.6 0.7 0.0024 18.6 0.7 2.3 1 1 1 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 KXZ47992.1 - 0.14 12.7 5.9 0.084 13.4 1.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger GRDP-like PF07173.12 KXZ47994.1 - 4.2e-05 24.2 0.7 0.0031 18.2 0.0 2.9 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like LRR_8 PF13855.6 KXZ47995.1 - 5.8e-11 42.0 4.8 1e-06 28.4 0.1 2.8 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXZ47995.1 - 4.7e-09 36.4 2.4 0.0028 18.0 0.2 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ47995.1 - 1.3e-05 25.0 6.9 0.41 11.4 0.1 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 KXZ47995.1 - 4.4e-05 23.2 1.5 1.4 9.2 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeat Guanylate_cyc PF00211.20 KXZ47997.1 - 0.0042 16.7 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FAE1_CUT1_RppA PF08392.12 KXZ47999.1 - 1.3e-16 60.8 0.0 1.6e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 KXZ47999.1 - 1e-05 25.6 0.1 2.8e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 KXZ47999.1 - 0.018 15.0 0.0 0.05 13.6 0.0 1.7 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain PvlArgDC PF01862.16 KXZ48000.1 - 0.035 13.9 0.3 0.045 13.5 0.3 1.1 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DUF3482 PF11981.8 KXZ48000.1 - 0.37 10.1 13.3 0.32 10.4 11.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) LMBR1 PF04791.16 KXZ48000.1 - 0.8 8.5 3.8 0.83 8.5 3.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.11 KXZ48000.1 - 2.6 8.1 17.6 3.1 7.8 17.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KXZ48000.1 - 2.9 6.3 11.2 3.8 5.9 11.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family 7tm_6 PF02949.20 KXZ48000.1 - 3.5 6.6 5.6 4 6.4 5.6 1.2 1 0 0 1 1 1 0 7tm Odorant receptor DOG1 PF14144.6 KXZ48000.1 - 4.3 7.6 6.8 0.84 9.9 2.2 2.0 2 1 0 2 2 2 0 Seed dormancy control TFIIA PF03153.13 KXZ48000.1 - 4.7 7.1 23.2 5.3 6.9 23.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2203 PF09969.9 KXZ48000.1 - 6.4 7.5 10.7 1.8 9.3 7.2 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CAP PF00188.26 KXZ48001.1 - 0.0073 17.1 0.0 0.0082 17.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Herpes_gE PF02480.16 KXZ48002.1 - 0.043 12.6 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Chlam_PMP PF02415.17 KXZ48003.1 - 0.09 13.3 0.4 0.09 13.3 0.4 13.4 13 1 0 13 13 13 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TPR_10 PF13374.6 KXZ48005.1 - 0.00053 19.8 6.5 0.066 13.1 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ48005.1 - 0.0016 18.7 4.0 0.068 13.5 1.1 4.2 3 1 2 5 5 5 2 Tetratricopeptide repeat Mem_trans PF03547.18 KXZ48005.1 - 0.026 12.9 0.1 0.041 12.3 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein TPR_14 PF13428.6 KXZ48005.1 - 0.051 14.4 11.1 1.2 10.1 0.2 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ48005.1 - 0.11 12.7 5.7 1 9.5 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat NIF PF03031.18 KXZ48007.1 - 1.6e-22 79.9 0.0 2.4e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KXZ48007.1 - 5.7e-09 35.6 0.1 1.2e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin family DUF4901 PF16244.5 KXZ48007.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) DUF705 PF05152.12 KXZ48007.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) NIF PF03031.18 KXZ48009.1 - 2.8e-22 79.2 0.0 1e-21 77.4 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase TPR_10 PF13374.6 KXZ48009.1 - 3.3e-19 68.1 4.2 2.7e-09 36.6 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ48009.1 - 1.8e-17 63.4 2.9 4.2e-17 62.2 2.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ48009.1 - 2.9e-09 36.3 2.0 0.00011 22.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ48009.1 - 1.5e-08 34.1 1.2 0.00028 20.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ48009.1 - 8.4e-07 28.6 1.7 0.0078 16.3 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ48009.1 - 1.8e-06 28.5 1.3 1.8e-06 28.5 1.3 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ48009.1 - 3.4e-05 24.3 0.9 0.00013 22.4 0.9 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ48009.1 - 9e-05 22.4 0.1 0.45 10.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_5 PF12688.7 KXZ48009.1 - 0.0012 19.1 0.3 0.72 10.1 0.0 2.8 1 1 1 2 2 2 2 Tetratrico peptide repeat MIT PF04212.18 KXZ48009.1 - 0.0027 17.8 0.2 2.2 8.4 0.0 2.5 1 1 1 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KXZ48009.1 - 0.015 15.3 0.1 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4901 PF16244.5 KXZ48009.1 - 0.03 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) TPR_11 PF13414.6 KXZ48009.1 - 0.035 13.8 0.9 11 5.8 0.1 2.9 2 0 0 2 2 2 0 TPR repeat AAA_25 PF13481.6 KXZ48009.1 - 0.042 13.4 0.6 0.12 12.0 0.6 1.7 1 1 0 1 1 1 0 AAA domain kleA_kleC PF17383.2 KXZ48009.1 - 0.48 10.8 4.3 1.7 9.0 0.3 3.0 2 1 1 3 3 2 0 Uncharacterized KorC regulated protein A TPR_12 PF13424.6 KXZ48010.1 - 1.2e-70 233.8 37.4 3.9e-18 65.5 4.1 6.1 3 1 4 7 7 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ48010.1 - 2.1e-48 161.0 36.0 4e-11 42.4 0.7 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ48010.1 - 7.1e-24 82.6 12.8 3.8e-05 23.3 0.2 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ48010.1 - 1.2e-21 75.0 25.3 3.2e-05 23.6 0.2 6.6 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ48010.1 - 1e-17 62.8 8.6 0.027 14.6 0.1 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ48010.1 - 1.2e-16 61.1 14.2 5.4e-07 30.2 1.0 8.6 4 3 4 8 8 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ48010.1 - 1.6e-16 59.0 24.3 0.0012 18.8 0.2 7.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ48010.1 - 7.3e-10 38.5 6.5 0.11 13.0 0.0 6.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_3 PF07720.12 KXZ48010.1 - 2.2e-09 37.1 7.9 2.2 8.4 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ48010.1 - 3.6e-09 37.0 24.9 7.9e-05 23.1 2.0 6.5 3 1 3 6 6 5 4 Tetratricopeptide repeat MIT PF04212.18 KXZ48010.1 - 4.8e-07 29.7 15.3 0.27 11.3 0.1 6.1 4 1 3 7 7 5 3 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KXZ48010.1 - 2.8e-06 26.9 10.5 2.9 7.6 0.1 6.1 5 0 0 5 5 5 3 TPR repeat Coatomer_E PF04733.14 KXZ48010.1 - 9.8e-06 25.2 5.3 0.59 9.5 0.2 4.5 1 1 3 4 4 4 2 Coatomer epsilon subunit ANAPC3 PF12895.7 KXZ48010.1 - 0.00013 22.1 18.6 0.085 13.1 1.7 4.9 2 1 2 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 KXZ48010.1 - 0.00024 21.3 23.3 0.0038 17.5 1.3 5.6 3 1 2 6 6 5 2 Tetratrico peptide repeat TPR_MalT PF17874.1 KXZ48010.1 - 0.00092 18.7 9.0 0.00092 18.7 9.0 3.4 3 1 0 4 4 3 2 MalT-like TPR region DUF713 PF05218.14 KXZ48010.1 - 0.0013 18.5 0.0 2.8 7.6 0.0 3.7 1 1 3 4 4 4 1 Protein of unknown function (DUF713) SHNi-TPR PF10516.9 KXZ48010.1 - 0.025 14.0 11.7 6.5 6.3 0.1 5.4 5 0 0 5 5 5 0 SHNi-TPR Fis1_TPR_C PF14853.6 KXZ48010.1 - 0.093 12.8 5.2 78 3.4 0.0 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat AAA_25 PF13481.6 KXZ48010.1 - 0.11 12.0 3.1 0.099 12.2 0.2 2.4 3 0 0 3 3 3 0 AAA domain Ctr PF04145.15 KXZ48011.1 - 6.6e-17 62.5 7.3 8.2e-15 55.7 7.3 2.4 1 1 0 1 1 1 1 Ctr copper transporter family ATPase_gene1 PF09527.10 KXZ48011.1 - 7.5 6.8 10.3 0.23 11.7 2.9 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter GYF PF02213.16 KXZ48013.1 - 6.4e-12 45.0 0.0 1.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 GYF domain EF-hand_7 PF13499.6 KXZ48014.1 - 1.6e-05 25.2 1.3 0.00011 22.5 1.6 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ48014.1 - 0.00017 20.9 1.3 0.033 13.7 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXZ48014.1 - 0.0011 18.8 2.9 0.88 9.7 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KXZ48014.1 - 0.052 13.4 1.1 2.9 7.8 0.2 2.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KXZ48014.1 - 0.65 9.6 4.4 0.27 10.8 0.4 2.3 2 0 0 2 2 2 0 EF hand MAM33 PF02330.16 KXZ48015.1 - 8.1e-32 110.9 1.3 9.5e-32 110.7 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein SQAPI PF16845.5 KXZ48016.1 - 3.1e-07 30.6 0.1 1.1e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor Cystatin PF00031.21 KXZ48016.1 - 6.3e-07 29.6 0.0 2.3e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Cystatin domain Med8 PF10232.9 KXZ48017.1 - 0.041 13.5 0.0 0.049 13.2 0.0 1.0 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 zf-CCHC PF00098.23 KXZ48019.1 - 4.9e-06 26.4 1.8 7.1e-06 25.9 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXZ48019.1 - 0.013 15.3 1.2 0.019 14.8 1.2 1.2 1 0 0 1 1 1 0 Zinc knuckle ZapB PF06005.12 KXZ48019.1 - 0.017 15.5 1.9 0.033 14.6 1.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 KXZ48019.1 - 0.18 12.5 0.1 0.27 11.9 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF2207 PF09972.9 KXZ48021.1 - 3.4 6.3 10.3 4 6.1 10.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SRCR PF00530.18 KXZ48022.1 - 1.2e-21 77.0 0.3 8.6e-21 74.3 0.2 2.5 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Chitin_synth_2 PF03142.15 KXZ48022.1 - 0.022 13.4 3.8 0.036 12.7 3.8 1.2 1 0 0 1 1 1 0 Chitin synthase JAMP PF05571.12 KXZ48022.1 - 0.064 12.9 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein DUF5417 PF17438.2 KXZ48022.1 - 0.075 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5417) SRCR_2 PF15494.6 KXZ48022.1 - 0.13 12.8 0.4 0.49 11.0 0.2 2.0 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain Ank_2 PF12796.7 KXZ48023.1 - 1.2e-12 48.2 2.2 3.8e-05 24.2 0.0 4.5 3 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48023.1 - 2.1e-10 40.9 4.8 0.18 12.5 0.4 6.9 4 1 3 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48023.1 - 0.0031 17.9 0.3 13 6.8 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 KXZ48023.1 - 0.013 15.8 4.0 14 6.2 0.0 4.9 3 2 2 5 5 5 0 Ankyrin repeats (many copies) PI3K_P85_iSH2 PF16454.5 KXZ48024.1 - 0.039 13.5 1.1 0.055 13.1 1.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain RRP36 PF06102.12 KXZ48024.1 - 0.059 13.3 0.8 0.084 12.8 0.8 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 APG6_N PF17675.1 KXZ48024.1 - 0.073 13.6 4.0 0.1 13.1 4.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region HAP1_N PF04849.13 KXZ48024.1 - 0.09 12.0 4.2 0.12 11.5 4.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Spc7 PF08317.11 KXZ48024.1 - 0.16 10.8 2.7 0.21 10.4 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FliG_C PF01706.16 KXZ48024.1 - 0.2 11.9 4.2 0.48 10.6 3.4 1.8 1 1 1 2 2 2 0 FliG C-terminal domain DASH_Spc34 PF08657.10 KXZ48024.1 - 0.43 10.3 2.4 0.59 9.9 2.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 TAF4 PF05236.14 KXZ48024.1 - 0.45 10.2 8.8 1 9.1 8.7 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family NYD-SP28_assoc PF14775.6 KXZ48025.1 - 0.051 13.7 1.0 0.088 12.9 1.0 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain Nsp1_C PF05064.13 KXZ48025.1 - 0.084 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region MS_channel PF00924.18 KXZ48026.1 - 1.3e-11 44.4 0.1 2.1e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXZ48026.1 - 0.0015 18.0 0.0 0.0055 16.2 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ48026.1 - 0.0086 15.5 0.2 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXZ48026.1 - 0.02 14.8 0.0 0.07 13.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KXZ48026.1 - 0.041 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Nt_Gln_amidase PF09764.9 KXZ48028.1 - 2.3e-17 63.2 0.0 3.5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal glutamine amidase TTL PF03133.15 KXZ48029.1 - 2.6e-45 154.8 0.0 1.1e-33 116.7 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ48029.1 - 1.4e-07 31.1 0.0 0.00047 19.5 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ48029.1 - 0.0044 16.3 0.0 0.029 13.6 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 KXZ48029.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Rossmann-like PF10727.9 KXZ48030.1 - 0.00021 21.1 0.7 0.00028 20.7 0.7 1.1 1 0 0 1 1 1 1 Rossmann-like domain F420_oxidored PF03807.17 KXZ48030.1 - 0.056 14.0 0.1 0.085 13.4 0.1 1.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ank_4 PF13637.6 KXZ48032.1 - 6e-06 26.7 4.5 0.68 10.6 0.2 6.1 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48032.1 - 1.1e-05 25.9 0.0 0.31 11.6 0.0 3.7 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ48032.1 - 1.6 9.2 6.2 8.9 6.8 0.1 4.6 5 2 1 6 6 6 0 Ankyrin repeats (many copies) CAP_N PF01213.19 KXZ48032.1 - 4.5 6.7 5.0 8.1 5.8 5.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ank_2 PF12796.7 KXZ48033.1 - 6.7e-06 26.6 0.0 0.037 14.6 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48033.1 - 3.7e-05 24.2 0.7 1 10.0 0.0 4.6 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48033.1 - 0.011 16.2 0.1 1.1e+02 4.0 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeat DUF1455 PF07306.11 KXZ48033.1 - 1.8 8.6 8.9 1.7 8.7 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) Pkinase PF00069.25 KXZ48034.1 - 8.3e-45 153.2 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48034.1 - 2.4e-39 135.2 0.0 3.4e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ48034.1 - 0.027 14.4 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ48034.1 - 0.033 12.9 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ48034.1 - 0.046 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MitMem_reg PF13012.6 KXZ48035.1 - 3.1e-23 82.3 0.0 4.5e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXZ48035.1 - 1.3e-17 63.8 0.0 2.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease 2OG-FeII_Oxy_2 PF13532.6 KXZ48036.1 - 0.00042 20.6 0.0 0.00054 20.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_21 PF13506.6 KXZ48037.1 - 0.039 13.4 1.0 0.07 12.6 1.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 RRM_1 PF00076.22 KXZ48038.1 - 8e-10 38.4 0.0 0.00057 19.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ48038.1 - 0.0073 16.1 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif MFS_5 PF05631.14 KXZ48039.1 - 1.1e-123 412.6 13.3 1.3e-123 412.4 13.3 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KXZ48039.1 - 3.2e-11 42.7 22.2 3.2e-11 42.7 22.2 3.1 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ48039.1 - 6.4e-06 25.3 8.8 0.0011 17.9 1.2 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter FixQ PF05545.11 KXZ48039.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF3707 PF12499.8 KXZ48041.1 - 4.1e-09 37.1 1.1 8.4e-08 32.9 1.1 2.2 1 1 0 1 1 1 1 Pherophorin DnaJ_C PF01556.18 KXZ48044.1 - 3.6e-29 101.8 0.0 3.9e-28 98.4 0.0 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXZ48044.1 - 8.6e-19 67.4 0.4 1.4e-18 66.8 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KXZ48044.1 - 0.12 12.4 0.0 0.8 9.7 0.0 2.1 1 1 1 2 2 2 0 A repeated domain in UCH-protein 6PF2K PF01591.18 KXZ48045.1 - 3.5e-19 69.0 0.0 4.8e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 KXZ48045.1 - 0.062 13.5 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXZ48045.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.21 KXZ48045.1 - 0.28 10.6 0.0 0.4 10.1 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family 6PF2K PF01591.18 KXZ48046.1 - 5.5e-42 143.6 0.1 8e-42 143.0 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXZ48046.1 - 4.6e-37 127.6 0.0 8.9e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.32 KXZ48050.1 - 1e-07 32.5 1.3 0.86 10.6 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Pyr_redox_2 PF07992.14 KXZ48051.1 - 3.2e-32 111.9 0.1 7.7e-27 94.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ48051.1 - 1.2e-08 35.4 0.4 2.6e-08 34.3 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ48051.1 - 0.0079 15.8 0.2 0.036 13.7 0.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Arg_decarbox_C PF17944.1 KXZ48051.1 - 0.096 13.3 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension Lycopene_cycl PF05834.12 KXZ48051.1 - 0.11 11.5 0.0 3.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein PAP1 PF08601.10 KXZ48051.1 - 1.9 8.1 4.6 2.9 7.5 4.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 TFIIS_M PF07500.14 KXZ48054.1 - 1.3e-11 45.0 0.2 1.7e-11 44.6 0.2 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KXZ48054.1 - 0.098 12.5 2.3 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) TF_Zn_Ribbon PF08271.12 KXZ48054.1 - 0.9 9.1 4.9 1.5 8.4 0.7 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Nop53 PF07767.11 KXZ48055.1 - 0.011 15.2 1.9 0.013 14.9 1.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) zf-MYND PF01753.18 KXZ48057.1 - 3.2e-07 30.3 10.5 3.2e-07 30.3 10.5 1.8 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KXZ48057.1 - 5.7 7.3 7.9 11 6.4 7.9 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF775 PF05603.12 KXZ48058.1 - 2.2e-10 40.4 0.0 2.3e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) EF1G PF00647.19 KXZ48059.1 - 2.8e-12 46.6 0.0 6.1e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain Band_7 PF01145.25 KXZ48060.1 - 3.2e-26 92.4 0.0 3.2e-26 92.4 0.0 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KXZ48060.1 - 0.058 13.1 0.1 0.098 12.4 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DAO PF01266.24 KXZ48061.1 - 6.1e-39 134.6 14.6 7.4e-39 134.3 14.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ48061.1 - 0.00019 20.8 2.8 0.033 13.4 1.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXZ48061.1 - 0.0013 19.0 0.4 0.0013 19.0 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KXZ48061.1 - 0.0027 17.6 0.4 0.0027 17.6 0.4 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXZ48061.1 - 0.0077 16.2 1.6 3.4 7.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXZ48061.1 - 0.008 15.5 3.2 0.008 15.5 3.2 2.3 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXZ48061.1 - 0.042 14.4 0.9 0.17 12.5 0.9 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXZ48061.1 - 0.12 11.4 6.7 2.6 7.0 3.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KXZ48061.1 - 0.2 11.0 0.6 0.51 9.7 0.6 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KXZ48061.1 - 4.4 7.4 5.2 3.6 7.7 0.2 2.5 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain HI0933_like PF03486.14 KXZ48061.1 - 8.4 5.0 6.5 2.4 6.7 2.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pkinase PF00069.25 KXZ48063.1 - 1.7e-08 34.1 0.0 2.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48063.1 - 0.22 10.7 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DEC-1_N PF04625.13 KXZ48063.1 - 1.2 8.1 9.4 3.1 6.7 9.4 1.8 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peptidase_M24_C PF16188.5 KXZ48064.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 DUF572 PF04502.13 KXZ48065.1 - 0.46 10.1 3.5 0.82 9.2 3.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) TssC PF17541.2 KXZ48065.1 - 2.2 7.0 4.1 3.3 6.4 4.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB FAD_binding_3 PF01494.19 KXZ48066.1 - 5.1e-13 49.0 0.1 6.6e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXZ48066.1 - 1.1e-11 44.5 1.2 6.5e-06 25.6 0.2 1.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ48066.1 - 6.6e-09 35.8 5.9 3.8e-06 26.7 0.2 2.5 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXZ48066.1 - 1.2e-07 31.8 3.3 4.1e-07 30.1 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXZ48066.1 - 3e-06 26.7 0.5 7.7e-06 25.3 0.1 1.9 2 1 0 2 2 2 1 Thi4 family GIDA PF01134.22 KXZ48066.1 - 3.2e-06 26.5 0.6 5.2e-06 25.8 0.6 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXZ48066.1 - 2.5e-05 23.3 0.1 0.00027 19.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 KXZ48066.1 - 3e-05 22.9 0.1 0.00018 20.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KXZ48066.1 - 4e-05 22.9 0.2 0.00012 21.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KXZ48066.1 - 9.4e-05 22.9 0.0 0.00026 21.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ48066.1 - 0.0089 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXZ48066.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXZ48066.1 - 0.032 13.9 0.1 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MIB_HERC2 PF06701.13 KXZ48067.1 - 2e-06 28.0 2.7 2e-06 28.0 2.7 2.0 2 0 0 2 2 2 1 Mib_herc2 HTH_30 PF13556.6 KXZ48067.1 - 0.021 14.6 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Uso1_p115_C PF04871.13 KXZ48067.1 - 3.9 7.8 6.5 8.6 6.7 6.5 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3138 PF11336.8 KXZ48067.1 - 6.1 5.3 17.8 10 4.6 17.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Nucleoside_tran PF01733.18 KXZ48068.1 - 7.2e-24 84.7 0.1 2.6e-23 82.9 0.1 1.8 1 1 0 1 1 1 1 Nucleoside transporter tRNA-synt_1 PF00133.22 KXZ48070.1 - 1.9e-25 89.2 0.0 1.7e-15 56.3 0.0 3.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Methyltransf_11 PF08241.12 KXZ48071.1 - 4.6e-08 33.6 0.0 8.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ48071.1 - 7.1e-06 26.6 0.0 2.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ48071.1 - 0.00035 21.3 0.0 0.00067 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ48071.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KXZ48071.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 KXZ48071.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ48071.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KXZ48071.1 - 0.24 11.2 0.0 0.37 10.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase SET PF00856.28 KXZ48073.1 - 0.022 15.2 0.0 0.73 10.2 0.0 3.0 2 1 0 2 2 2 0 SET domain DUF2457 PF10446.9 KXZ48073.1 - 0.66 9.1 22.4 0.014 14.5 8.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 KXZ48073.1 - 0.82 9.0 27.8 0.065 12.7 15.5 2.1 2 0 0 2 2 2 0 SDA1 DUF2786 PF10979.8 KXZ48074.1 - 0.027 14.4 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Trypan_PARP PF05887.11 KXZ48074.1 - 0.18 11.8 35.6 0.082 12.9 20.0 2.3 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 KXZ48075.1 - 7.8 4.5 6.2 14 3.6 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 KXZ48076.1 - 3e-18 66.2 0.0 3.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48076.1 - 3.5e-09 36.3 0.0 3.5e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ48077.1 - 0.0005 19.5 0.0 0.00055 19.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48077.1 - 0.00056 19.3 0.0 0.00063 19.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KXZ48079.1 - 0.0016 19.0 0.6 0.62 10.7 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48079.1 - 0.014 15.9 1.0 0.41 11.3 0.2 2.2 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) DUF434 PF04256.12 KXZ48079.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF434) RNA_pol_Rpc4 PF05132.14 KXZ48081.1 - 0.0018 18.7 4.7 0.0022 18.4 4.7 1.0 1 0 0 1 1 1 1 RNA polymerase III RPC4 GARP PF16731.5 KXZ48081.1 - 0.19 11.4 24.2 0.23 11.2 24.2 1.0 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma CPSF100_C PF13299.6 KXZ48081.1 - 1.1 9.4 7.1 1.2 9.3 7.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SspB PF04386.13 KXZ48081.1 - 1.6 8.6 9.0 1.8 8.5 9.0 1.1 1 0 0 1 1 1 0 Stringent starvation protein B AIF_C PF14721.6 KXZ48081.1 - 1.7 9.0 4.9 1.9 8.9 4.9 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SMBP PF16785.5 KXZ48081.1 - 1.8 8.8 23.9 12 6.2 23.9 1.8 1 1 1 2 2 2 0 Small metal-binding protein CLN3 PF02487.17 KXZ48081.1 - 2 7.3 3.5 2.1 7.3 3.5 1.0 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 KXZ48081.1 - 2.2 6.1 5.7 2.1 6.2 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2229 PF09989.9 KXZ48081.1 - 3.2 7.4 6.8 3.6 7.2 6.8 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) eIF3_subunit PF08597.10 KXZ48081.1 - 3.4 7.5 21.6 3.5 7.5 21.6 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4746 PF15928.5 KXZ48081.1 - 3.5 7.0 13.2 4 6.8 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CCDC53 PF10152.9 KXZ48081.1 - 3.6 8.0 8.6 4.1 7.8 8.6 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 KXZ48081.1 - 3.9 6.1 9.5 4.5 5.9 9.5 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KXZ48081.1 - 4.4 7.3 5.8 4.8 7.2 5.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PDGLE PF13190.6 KXZ48081.1 - 6.6 6.7 6.0 11 5.9 6.0 1.6 1 1 0 1 1 1 0 PDGLE domain ATP-synt_B PF00430.18 KXZ48081.1 - 9.4 6.3 21.4 10 6.2 21.4 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DDRGK PF09756.9 KXZ48081.1 - 9.8 5.7 20.7 11 5.5 20.7 1.1 1 0 0 1 1 1 0 DDRGK domain SET PF00856.28 KXZ48083.1 - 0.045 14.1 0.1 0.58 10.5 0.0 2.9 3 1 0 3 3 3 0 SET domain SET PF00856.28 KXZ48084.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 SET domain SET PF00856.28 KXZ48086.1 - 0.097 13.1 0.0 0.23 11.9 0.0 1.6 1 1 1 2 2 2 0 SET domain SET PF00856.28 KXZ48088.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.7 1 1 0 1 1 1 0 SET domain SET PF00856.28 KXZ48090.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.6 1 1 0 1 1 1 0 SET domain SET PF00856.28 KXZ48091.1 - 0.005 17.2 0.0 0.0075 16.7 0.0 1.4 1 0 0 1 1 1 1 SET domain Ion_trans PF00520.31 KXZ48093.1 - 6.8e-13 48.4 0.8 1.1e-12 47.7 0.8 1.3 1 0 0 1 1 1 1 Ion transport protein WD40 PF00400.32 KXZ48093.1 - 3.7e-08 33.9 2.4 0.19 12.7 0.0 5.7 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ48093.1 - 7.3e-06 26.2 0.0 1.8 8.9 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXZ48093.1 - 0.00019 21.3 0.0 0.45 10.5 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXZ48093.1 - 0.00064 18.8 0.0 0.98 8.3 0.0 2.7 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_5 PF13857.6 KXZ48093.1 - 0.0067 16.7 0.1 0.022 15.1 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Med4 PF10018.9 KXZ48093.1 - 0.032 13.9 0.7 0.052 13.2 0.7 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Cytochrom_D1 PF02239.16 KXZ48093.1 - 0.06 11.9 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ank_2 PF12796.7 KXZ48093.1 - 0.091 13.4 0.0 0.33 11.6 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Fzo_mitofusin PF04799.13 KXZ48093.1 - 0.098 12.2 4.0 0.21 11.1 4.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region PKD_channel PF08016.12 KXZ48093.1 - 0.12 11.0 8.1 0.027 13.1 0.7 2.1 2 0 0 2 2 2 0 Polycystin cation channel Ank_4 PF13637.6 KXZ48093.1 - 0.12 13.0 0.0 0.42 11.3 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) LOH1CR12 PF10158.9 KXZ48093.1 - 0.19 11.7 0.4 0.35 10.9 0.4 1.3 1 0 0 1 1 1 0 Tumour suppressor protein CLZ PF16526.5 KXZ48093.1 - 0.26 11.7 6.1 0.16 12.4 0.8 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Dict-STAT-coil PF09267.10 KXZ48093.1 - 0.61 10.5 3.8 1.2 9.6 3.8 1.4 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil Hira PF07569.11 KXZ48093.1 - 0.64 9.7 3.2 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split OmpH PF03938.14 KXZ48093.1 - 1.2 9.5 4.4 2 8.8 4.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Snapin_Pallidin PF14712.6 KXZ48093.1 - 4.6 7.7 7.4 1 9.8 1.3 2.5 1 1 1 2 2 2 0 Snapin/Pallidin MFS_1 PF07690.16 KXZ48094.1 - 3.4e-40 138.1 51.5 3.4e-40 138.1 51.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ48094.1 - 2.2e-07 30.1 7.7 2.2e-07 30.1 7.7 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Lactamase_B_2 PF12706.7 KXZ48095.1 - 4.3e-14 52.5 0.1 2.3e-07 30.6 0.0 2.4 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXZ48095.1 - 3.9e-05 23.7 0.1 0.00011 22.2 0.1 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PP2C PF00481.21 KXZ48096.1 - 5.9e-43 147.4 0.0 7e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C TetR_C_11 PF16859.5 KXZ48096.1 - 0.012 15.9 2.6 0.62 10.4 0.1 2.6 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GlcNAc PF11397.8 KXZ48097.1 - 3.8e-77 260.1 4.3 2.9e-65 221.0 2.7 3.0 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 KXZ48097.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2786 PF10979.8 KXZ48100.1 - 0.0029 17.5 0.2 0.4 10.7 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2786) SET PF00856.28 KXZ48101.1 - 0.0091 16.4 0.0 0.33 11.3 0.0 2.2 1 1 0 2 2 2 2 SET domain W2 PF02020.18 KXZ48102.1 - 2.4e-17 62.8 1.1 2.4e-17 62.8 1.1 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 KXZ48102.1 - 1.2e-09 38.2 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KXZ48102.1 - 3.8e-06 26.4 17.8 0.0086 15.8 4.5 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXZ48102.1 - 0.0014 19.0 0.1 0.0036 17.7 0.1 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain NOA36 PF06524.12 KXZ48102.1 - 0.0038 16.6 8.5 0.0038 16.6 8.5 2.2 3 0 0 3 3 3 1 NOA36 protein DUF4954 PF16314.5 KXZ48102.1 - 0.26 9.4 3.4 0.56 8.3 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KXZ48102.1 - 0.46 9.4 1.9 0.86 8.5 0.9 1.8 2 1 0 2 2 2 0 L-fucokinase RXT2_N PF08595.11 KXZ48102.1 - 0.78 9.8 3.9 2.1 8.3 3.9 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 KXZ48102.1 - 1.7 6.8 5.0 2.8 6.0 5.0 1.3 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.13 KXZ48102.1 - 7.1 5.1 7.5 11 4.5 7.5 1.2 1 0 0 1 1 1 0 Utp14 protein Guanylate_cyc PF00211.20 KXZ48103.1 - 5.9e-45 153.1 0.0 9.3e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ48106.1 - 3.1e-45 154.1 0.0 5.1e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Bap31_Bap29_C PF18035.1 KXZ48107.1 - 0.59 10.2 3.5 27 4.9 0.6 2.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Ank_2 PF12796.7 KXZ48109.1 - 4.8e-09 36.7 0.1 0.00032 21.2 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48109.1 - 1.3e-08 34.4 0.7 0.81 10.4 0.1 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KXZ48109.1 - 2e-08 34.6 0.6 0.0014 19.2 0.1 4.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48109.1 - 0.029 14.7 3.6 16 5.9 0.0 4.7 4 1 1 5 5 5 0 Ankyrin repeats (many copies) HAD PF12710.7 KXZ48109.1 - 0.12 12.8 0.6 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PP2C PF00481.21 KXZ48110.1 - 9e-40 136.9 0.8 2.6e-26 92.8 0.2 3.4 3 0 0 3 3 3 3 Protein phosphatase 2C IQ PF00612.27 KXZ48110.1 - 0.51 10.3 4.3 1.2 9.1 4.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Glyco_hydro_32N PF00251.20 KXZ48111.1 - 1.2e-50 172.9 0.0 2.2e-37 129.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXZ48111.1 - 3.7e-06 27.0 0.0 3.1e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KXZ48112.1 - 8.1e-55 186.5 0.0 4.5e-42 144.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXZ48112.1 - 0.0087 16.1 0.0 0.036 14.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal UPF0139 PF03669.13 KXZ48113.1 - 2.7e-10 40.0 0.0 3.3e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) PetG PF02529.15 KXZ48113.1 - 0.13 12.2 1.1 0.27 11.1 1.1 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 bZIP_1 PF00170.21 KXZ48115.1 - 0.00017 21.6 4.6 0.00017 21.6 4.6 2.0 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ48115.1 - 0.00021 21.3 7.0 0.00021 21.3 7.0 2.6 3 1 0 3 3 3 1 Basic region leucine zipper FoP_duplication PF13865.6 KXZ48116.1 - 0.041 14.4 2.5 0.041 14.4 2.5 2.8 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 FlgM PF04316.13 KXZ48116.1 - 0.15 12.5 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF3583 PF12126.8 KXZ48116.1 - 0.3 10.5 0.1 0.77 9.2 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3583) PS-DH PF14765.6 KXZ48117.1 - 0.0067 15.7 0.6 0.019 14.2 0.3 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase FAM176 PF14851.6 KXZ48117.1 - 0.024 14.3 0.0 0.079 12.6 0.0 1.9 2 0 0 2 2 2 0 FAM176 family Phage_holin_3_6 PF07332.11 KXZ48117.1 - 0.032 14.3 1.1 0.032 14.3 1.1 2.6 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Skp1 PF01466.19 KXZ48119.1 - 1.5e-30 105.0 0.9 3.4e-30 103.9 0.9 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXZ48119.1 - 5.2e-24 84.2 0.2 1.1e-23 83.1 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Thump_like PF18096.1 KXZ48119.1 - 0.024 14.5 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 THUMP domain-like LRR_6 PF13516.6 KXZ48120.1 - 4.2e-14 51.3 23.6 0.0053 16.7 0.0 10.4 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 KXZ48120.1 - 0.16 12.6 3.8 47 5.1 0.0 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat CAP_N PF01213.19 KXZ48120.1 - 0.21 11.0 5.4 3.9 6.9 0.2 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Aldedh PF00171.22 KXZ48121.1 - 1.9e-06 26.7 0.0 0.036 12.6 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family TPT PF03151.16 KXZ48122.1 - 3e-41 141.7 13.7 3.7e-41 141.4 13.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXZ48122.1 - 4.6e-11 42.5 13.8 6.5e-11 42.0 13.8 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXZ48122.1 - 2.1e-08 34.4 19.9 0.00036 20.7 9.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family COX8 PF02285.15 KXZ48122.1 - 5 7.1 5.5 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII CLP_protease PF00574.23 KXZ48123.1 - 4.4e-74 248.3 0.0 6.1e-74 247.9 0.0 1.1 1 0 0 1 1 1 1 Clp protease RNB PF00773.19 KXZ48125.1 - 5.5e-63 213.3 0.0 1.1e-61 209.0 0.0 2.1 1 1 0 1 1 1 1 RNB domain Dimerisation PF08100.11 KXZ48125.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain AMP-binding PF00501.28 KXZ48126.1 - 4.9e-95 318.6 0.0 1.8e-93 313.5 0.0 2.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ48126.1 - 0.0038 18.2 0.0 0.014 16.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VWA PF00092.28 KXZ48127.1 - 5.5e-14 52.8 0.0 1.8e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXZ48127.1 - 9.1e-10 38.7 0.1 2.9e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXZ48127.1 - 3.9e-07 30.7 0.0 1.7e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain TPT PF03151.16 KXZ48128.1 - 7.4e-10 38.6 18.8 8.6e-10 38.4 18.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ48128.1 - 9.4e-06 25.8 30.3 0.00078 19.6 12.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXZ48128.1 - 0.069 12.3 17.1 0.28 10.3 17.1 1.9 1 1 0 1 1 1 0 UAA transporter family Phage_holin_2_3 PF16080.5 KXZ48128.1 - 1 9.2 4.3 4.3 7.2 2.6 2.9 1 1 1 2 2 2 0 Bacteriophage holin family HP1 VWA PF00092.28 KXZ48129.1 - 4.2e-14 53.2 0.0 9.4e-13 48.8 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXZ48129.1 - 2.1e-08 34.3 0.3 3e-07 30.5 0.0 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXZ48129.1 - 2.9e-07 31.1 0.0 1.8e-06 28.6 0.0 2.4 1 0 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.8 KXZ48129.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain TPT PF03151.16 KXZ48130.1 - 4.4e-10 39.4 18.4 5.1e-10 39.2 18.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ48130.1 - 5.7e-06 26.6 30.0 0.00049 20.3 11.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXZ48130.1 - 0.084 12.1 17.1 0.32 10.1 17.1 1.9 1 1 0 1 1 1 0 UAA transporter family Sterol_MT_C PF08498.10 KXZ48131.1 - 3.1e-21 75.4 0.0 6.1e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KXZ48131.1 - 2.1e-20 73.2 0.0 3.3e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ48131.1 - 9.6e-17 61.5 0.0 3.2e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ48131.1 - 1.9e-16 60.2 0.0 3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXZ48131.1 - 2.1e-13 50.2 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXZ48131.1 - 1.6e-11 44.4 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ48131.1 - 3.1e-08 34.3 0.0 6.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ48131.1 - 9.9e-07 28.3 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXZ48131.1 - 0.00067 19.5 0.0 0.0069 16.2 0.0 2.0 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KXZ48131.1 - 0.006 16.2 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 KXZ48131.1 - 0.043 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Exo_endo_phos PF03372.23 KXZ48132.1 - 4.3e-10 39.5 5.5 8.7e-09 35.2 2.7 3.2 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family DUF3606 PF12244.8 KXZ48133.1 - 0.02 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DUF1145 PF06611.12 KXZ48135.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) Metallophos PF00149.28 KXZ48137.1 - 7.2e-09 36.4 0.0 0.0038 17.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Spt5_N PF11942.8 KXZ48137.1 - 0.2 12.7 8.3 5.6 8.0 3.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-MYND PF01753.18 KXZ48138.1 - 1.1e-07 31.8 4.7 2.3e-07 30.8 4.7 1.5 1 0 0 1 1 1 1 MYND finger CLLAC PF15675.5 KXZ48138.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain FH2 PF02181.23 KXZ48139.1 - 0.00024 20.3 3.6 0.00034 19.8 3.6 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain GCR1_C PF12550.8 KXZ48139.1 - 0.015 15.6 0.9 4.2 7.7 0.2 2.8 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Bap31_Bap29_C PF18035.1 KXZ48139.1 - 0.12 12.5 2.5 0.17 11.9 0.5 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pet191_N PF10203.9 KXZ48139.1 - 0.15 12.4 0.3 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 SEA PF01390.20 KXZ48139.1 - 0.18 11.9 0.0 0.61 10.2 0.0 1.9 1 1 1 2 2 2 0 SEA domain Uso1_p115_C PF04871.13 KXZ48139.1 - 0.21 11.9 15.5 0.038 14.3 11.1 1.9 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.12 KXZ48139.1 - 0.41 11.1 16.5 1.1 9.7 9.7 3.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PRKCSH-like PF12999.7 KXZ48139.1 - 0.59 9.9 3.8 0.49 10.2 0.2 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like Fez1 PF06818.15 KXZ48139.1 - 1.3 9.4 18.1 2.6 8.5 18.1 1.5 1 0 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 KXZ48139.1 - 1.7 6.5 5.9 2.2 6.1 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KXZ48139.1 - 1.7 7.4 12.8 2.9 6.7 12.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KXZ48139.1 - 3.3 8.1 10.6 15 6.0 1.7 3.8 1 1 3 4 4 4 0 Csm1 N-terminal domain GAS PF13851.6 KXZ48139.1 - 4.4 6.6 15.1 12 5.2 15.2 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KXZ48139.1 - 5.2 7.1 16.1 0.71 9.9 5.1 2.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 KXZ48139.1 - 6 7.0 19.8 0.48 10.6 7.8 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Metallophos PF00149.28 KXZ48140.1 - 1.9e-15 57.9 0.1 1.6e-06 28.8 0.2 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KXZ48140.1 - 2e-07 31.8 2.2 2e-07 31.7 0.1 2.3 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KXZ48140.1 - 0.00077 20.0 0.0 0.0023 18.5 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 KXZ48140.1 - 0.034 14.3 0.1 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Amidase_2 PF01510.25 KXZ48140.1 - 0.09 13.2 0.0 0.41 11.1 0.0 2.2 1 1 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Nop14 PF04147.12 KXZ48140.1 - 0.23 9.6 27.4 0.32 9.2 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXZ48140.1 - 1.8 7.9 29.1 2.7 7.3 29.1 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KXZ48140.1 - 6 5.5 7.6 8.3 5.1 7.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 KXZ48140.1 - 6.9 6.4 10.9 12 5.7 10.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Aldedh PF00171.22 KXZ48141.1 - 1.2e-182 607.6 0.0 1.3e-182 607.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_Al_protease PF02983.14 KXZ48141.1 - 0.14 12.2 9.5 0.079 13.0 5.6 2.5 2 0 0 2 2 2 0 Alpha-lytic protease prodomain WW PF00397.26 KXZ48143.1 - 1.2e-08 34.8 5.7 3.3e-08 33.5 5.7 1.8 1 0 0 1 1 1 1 WW domain Ank_4 PF13637.6 KXZ48146.1 - 0.1 13.2 0.2 0.89 10.2 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48146.1 - 0.12 13.0 1.2 5.3 7.9 0.1 3.5 3 0 0 3 3 3 0 Ankyrin repeat Pkinase PF00069.25 KXZ48147.1 - 4.5e-68 229.5 0.0 1.1e-42 146.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48147.1 - 6.8e-27 94.4 0.0 7.6e-20 71.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Torus PF16131.5 KXZ48148.1 - 2.7e-28 98.8 0.8 7.5e-28 97.4 0.0 2.0 2 0 0 2 2 2 1 Torus domain UBA PF00627.31 KXZ48148.1 - 9.6e-14 51.0 2.8 3.4e-07 30.0 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain RRM_1 PF00076.22 KXZ48148.1 - 2e-05 24.3 0.0 4.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA_3 PF09288.10 KXZ48148.1 - 0.0041 16.9 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain zf-CCCH_4 PF18044.1 KXZ48148.1 - 0.28 11.0 6.1 0.46 10.3 6.1 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXZ48148.1 - 0.41 10.8 6.6 0.69 10.0 6.6 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 KXZ48148.1 - 3 7.9 6.5 5.4 7.1 6.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.10 KXZ48148.1 - 7 7.0 0.0 7 7.0 0.0 4.1 3 1 0 3 3 3 0 HBS1 N-terminus EF-hand_7 PF13499.6 KXZ48149.1 - 2.9e-14 53.3 5.7 1.4e-07 31.8 0.6 4.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 KXZ48149.1 - 3.2e-13 48.2 7.6 1e-05 24.7 1.1 4.3 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KXZ48149.1 - 7.4e-12 44.2 1.1 6.9e-05 22.2 0.0 3.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXZ48149.1 - 1.2e-11 44.3 8.1 0.0002 21.1 0.6 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KXZ48149.1 - 4.9e-08 32.3 1.9 0.00012 21.7 0.1 5.2 9 0 0 9 9 9 2 EF-hand domain EF-hand_4 PF12763.7 KXZ48149.1 - 0.00025 20.9 0.6 0.013 15.4 0.2 2.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Cbl_N2 PF02761.14 KXZ48149.1 - 0.013 16.2 1.3 2 9.2 0.3 3.2 2 1 1 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain SPARC_Ca_bdg PF10591.9 KXZ48149.1 - 0.037 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 KXZ48149.1 - 0.13 12.5 0.1 5.6 7.1 0.0 2.6 3 0 0 3 3 3 0 p25-alpha Ribosomal_60s PF00428.19 KXZ48152.1 - 0.033 14.8 0.1 0.033 14.8 0.1 5.0 5 0 0 5 5 5 0 60s Acidic ribosomal protein HisKA_3 PF07730.13 KXZ48153.1 - 2 9.0 10.7 0.045 14.3 2.3 2.7 4 0 0 4 4 4 0 Histidine kinase PMSR PF01625.21 KXZ48154.1 - 8.3e-63 211.1 0.4 1.1e-62 210.7 0.4 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase WD40 PF00400.32 KXZ48155.1 - 3.4e-16 59.3 20.5 0.01 16.6 0.3 9.1 9 0 0 9 9 9 5 WD domain, G-beta repeat F-box-like PF12937.7 KXZ48155.1 - 7.5e-12 44.9 4.0 1.8e-11 43.7 4.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ48155.1 - 3.7e-09 36.2 0.2 7.9e-09 35.2 0.2 1.5 1 0 0 1 1 1 1 F-box domain FAM47 PF14642.6 KXZ48155.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 FAM47 family Helicase_C PF00271.31 KXZ48156.1 - 3.9e-11 43.3 0.0 8.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DND1_DSRM PF14709.7 KXZ48156.1 - 0.015 15.5 0.0 0.088 13.1 0.0 2.4 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ATPase PF06745.13 KXZ48156.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiC DEAD PF00270.29 KXZ48156.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 KXZ48156.1 - 0.62 10.4 0.0 0.62 10.4 0.0 3.8 3 0 0 3 3 3 0 AAA ATPase domain OB_NTP_bind PF07717.16 KXZ48157.1 - 2.5e-17 63.0 0.0 3.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Ribosomal_L28 PF00830.19 KXZ48158.1 - 9.6e-21 73.7 7.5 1.7e-20 73.0 7.5 1.4 1 0 0 1 1 1 1 Ribosomal L28 family ABC_tran PF00005.27 KXZ48161.1 - 5.5e-25 88.5 0.0 1.9e-24 86.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_tran_CTD PF16326.5 KXZ48161.1 - 1.2e-09 38.3 3.7 1.2e-09 38.3 3.7 1.9 2 0 0 2 2 1 1 ABC transporter C-terminal domain AAA_21 PF13304.6 KXZ48161.1 - 2.1e-08 34.3 1.4 6.8e-05 22.8 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXZ48161.1 - 1e-05 26.1 3.0 0.00033 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXZ48161.1 - 0.00025 20.5 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ48161.1 - 0.0024 17.6 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KXZ48161.1 - 0.01 15.6 0.1 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 KXZ48161.1 - 0.016 13.9 1.2 0.1 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain PTN13_u3 PF16599.5 KXZ48161.1 - 0.029 14.4 3.8 0.048 13.7 3.8 1.3 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ DUF4407 PF14362.6 KXZ48161.1 - 0.045 13.1 8.0 0.064 12.6 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 KXZ48161.1 - 0.084 13.2 0.5 0.19 12.1 0.5 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps5 PF09325.10 KXZ48161.1 - 0.11 12.1 3.0 3 7.3 0.1 2.7 3 0 0 3 3 3 0 Vps5 C terminal like MMR_HSR1 PF01926.23 KXZ48161.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 KXZ48161.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.8 2 1 1 3 3 3 0 ABC transporter IMUP PF15761.5 KXZ48161.1 - 0.44 11.3 10.3 0.79 10.4 10.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein TMF_TATA_bd PF12325.8 KXZ48161.1 - 0.92 9.7 4.4 0.48 10.6 1.0 2.1 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KXZ48161.1 - 2.9 7.7 5.5 0.35 10.7 0.6 2.1 2 0 0 2 2 2 0 Septum formation initiator Med3 PF11593.8 KXZ48161.1 - 6.1 5.9 7.5 8.4 5.5 7.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UCH PF00443.29 KXZ48162.1 - 9.3e-24 84.3 0.0 1.1e-23 84.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ48162.1 - 2.2e-12 47.2 0.0 4.3e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FCSD-flav_bind PF09242.11 KXZ48162.1 - 0.014 15.7 0.1 0.03 14.7 0.1 1.6 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding NYN PF01936.18 KXZ48163.1 - 0.011 16.3 0.0 1.7 9.2 0.0 2.5 2 1 0 2 2 2 0 NYN domain zf-C2H2 PF00096.26 KXZ48163.1 - 0.011 16.2 3.0 0.021 15.3 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXZ48163.1 - 0.015 16.1 3.1 0.05 14.5 3.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXZ48163.1 - 0.036 14.4 2.4 0.061 13.7 2.4 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 KXZ48163.1 - 0.037 12.6 3.1 0.055 12.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 KXZ48163.1 - 0.062 13.6 2.1 0.13 12.5 2.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXZ48163.1 - 0.11 13.1 1.7 0.23 12.1 1.7 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KXZ48163.1 - 0.17 12.2 2.2 0.31 11.4 2.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KXZ48163.1 - 0.21 11.5 0.2 0.34 10.8 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) CTU2 PF10288.9 KXZ48163.1 - 0.58 10.4 2.7 0.28 11.4 0.2 1.7 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 ARS2 PF04959.13 KXZ48163.1 - 3.6 7.9 10.4 3.6 7.9 0.2 3.2 3 0 0 3 3 3 0 Arsenite-resistance protein 2 GATA PF00320.27 KXZ48165.1 - 5.2e-13 48.4 4.3 1e-12 47.5 4.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Caldesmon PF02029.15 KXZ48165.1 - 0.00039 19.3 22.1 0.00086 18.2 22.1 1.5 1 1 0 1 1 1 1 Caldesmon TF_Zn_Ribbon PF08271.12 KXZ48165.1 - 0.0056 16.2 1.2 0.0093 15.5 1.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KXZ48165.1 - 0.18 11.9 0.5 0.44 10.7 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF3493 PF11998.8 KXZ48166.1 - 1.2e-20 73.5 1.4 2e-20 72.7 1.4 1.4 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 FTCD_N PF07837.12 KXZ48167.1 - 2.9e-43 147.7 2.1 2.1e-31 109.1 0.1 2.8 3 0 0 3 3 3 2 Formiminotransferase domain, N-terminal subdomain CBM_21 PF03370.13 KXZ48168.1 - 2.1e-10 40.8 0.0 5.7e-09 36.1 0.0 2.2 1 1 1 2 2 2 2 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXZ48168.1 - 0.00043 20.8 1.7 0.00086 19.8 0.9 2.0 2 1 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) SRP68 PF16969.5 KXZ48170.1 - 2.1e-105 353.9 12.1 4.5e-105 352.8 12.1 1.5 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 OSK PF17182.4 KXZ48170.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 OSK domain ATP_bind_1 PF03029.17 KXZ48171.1 - 1.2e-71 241.3 0.0 1.6e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KXZ48171.1 - 1.5e-05 25.0 0.0 3.6e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXZ48171.1 - 3.9e-05 24.1 1.1 5.7e-05 23.6 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 KXZ48171.1 - 6.9e-05 22.5 0.1 0.00049 19.7 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KXZ48171.1 - 7.3e-05 22.1 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain GTP_EFTU PF00009.27 KXZ48171.1 - 0.0003 20.4 0.1 0.005 16.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KXZ48171.1 - 0.00038 21.0 0.1 0.0015 19.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 KXZ48171.1 - 0.00069 18.7 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 KXZ48171.1 - 0.00079 19.0 0.0 0.055 13.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B SRP54 PF00448.22 KXZ48171.1 - 0.00098 18.8 0.0 0.0026 17.4 0.0 1.7 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain NACHT PF05729.12 KXZ48171.1 - 0.0011 18.9 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXZ48171.1 - 0.0019 18.5 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXZ48171.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ48171.1 - 0.0023 18.3 0.1 0.0052 17.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ48171.1 - 0.0047 17.1 0.0 0.0047 17.1 0.0 2.3 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KXZ48171.1 - 0.0059 15.9 0.0 0.0059 15.9 0.0 1.9 2 0 0 2 2 1 1 Zeta toxin APS_kinase PF01583.20 KXZ48171.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 KXZ48171.1 - 0.0071 16.3 0.4 0.59 10.0 0.0 3.0 3 1 0 3 3 3 1 RsgA GTPase AAA_30 PF13604.6 KXZ48171.1 - 0.0078 16.0 0.0 0.0078 16.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ48171.1 - 0.009 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 KXZ48171.1 - 0.01 15.6 0.1 0.037 13.8 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 KXZ48171.1 - 0.022 14.2 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MFAP1 PF06991.11 KXZ48171.1 - 0.026 14.4 0.5 0.026 14.4 0.5 1.4 2 0 0 2 2 1 0 Microfibril-associated/Pre-mRNA processing NTPase_1 PF03266.15 KXZ48171.1 - 0.028 14.4 0.0 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 KXZ48171.1 - 0.039 13.6 1.2 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.14 KXZ48171.1 - 0.04 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KXZ48171.1 - 0.053 14.0 0.0 0.053 14.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Torsin PF06309.11 KXZ48171.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_7 PF12775.7 KXZ48171.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KXZ48171.1 - 0.081 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXZ48171.1 - 0.084 13.1 1.6 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXZ48171.1 - 0.094 12.5 0.1 0.094 12.5 0.1 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 KXZ48171.1 - 0.1 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATPase PF06745.13 KXZ48171.1 - 0.1 11.9 0.5 0.16 11.3 0.0 1.5 2 0 0 2 2 1 0 KaiC ATPase_2 PF01637.18 KXZ48171.1 - 0.1 12.5 0.3 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KXZ48171.1 - 0.13 11.5 0.3 0.59 9.3 0.3 1.9 1 1 0 1 1 1 0 KAP family P-loop domain G-alpha PF00503.20 KXZ48171.1 - 0.13 11.4 0.0 1 8.4 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 KXZ48171.1 - 0.16 11.4 0.1 0.41 10.0 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DLIC PF05783.11 KXZ48171.1 - 0.34 9.7 0.0 0.34 9.7 0.0 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) UvrD-helicase PF00580.21 KXZ48171.1 - 0.47 9.9 1.2 0.6 9.6 0.2 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TsaE PF02367.17 KXZ48171.1 - 0.53 10.3 0.1 0.53 10.3 0.1 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KXZ48171.1 - 0.74 9.2 0.0 0.74 9.2 0.0 2.2 3 0 0 3 3 2 0 PhoH-like protein NADH-u_ox-rdase PF10785.9 KXZ48172.1 - 5.3e-13 49.5 0.1 6.5e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4564 PF15169.6 KXZ48172.1 - 0.16 11.7 0.4 0.23 11.1 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4564) DSPc PF00782.20 KXZ48173.1 - 4.9e-21 74.9 0.2 1.1e-20 73.8 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXZ48173.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TPR_12 PF13424.6 KXZ48174.1 - 2.2e-13 50.3 16.9 0.00066 19.9 0.0 5.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ48174.1 - 1.9e-05 24.4 9.1 0.68 9.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ48174.1 - 0.00074 20.1 3.7 0.00074 20.1 3.7 6.3 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ48174.1 - 0.017 15.1 7.1 0.78 9.9 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ48174.1 - 0.42 11.1 1.8 74 4.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ48174.1 - 0.86 9.5 6.9 27 4.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ48174.1 - 1.3 10.0 21.2 29 5.8 0.0 6.1 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ48174.1 - 1.4 9.2 18.5 7.5 6.9 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Amidinotransf PF02274.17 KXZ48175.1 - 1.3e-42 146.2 0.1 9.5e-42 143.3 0.1 2.0 1 1 0 1 1 1 1 Amidinotransferase Proteasome PF00227.26 KXZ48176.1 - 8e-37 126.6 0.0 9e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RVT_2 PF07727.14 KXZ48177.1 - 2.2e-09 37.3 0.0 8.3e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 KXZ48178.1 - 4.7e-36 124.4 0.0 7.8e-33 113.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ48178.1 - 1.7e-31 109.6 0.0 7.6e-29 100.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ48178.1 - 0.00054 20.0 3.4 0.0065 16.4 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ48178.1 - 0.049 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GCFC PF07842.12 KXZ48179.1 - 2.7e-11 43.6 0.0 9.5e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Spc7 PF08317.11 KXZ48179.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein JHD PF17811.1 KXZ48180.1 - 0.13 12.9 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Jumonji helical domain SUIM_assoc PF16619.5 KXZ48180.1 - 5.2 7.2 5.9 0.73 9.9 0.8 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 KXZ48181.1 - 2.9e-45 154.7 0.0 2.1e-44 151.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48181.1 - 4.3e-25 88.5 0.0 3.4e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ48181.1 - 0.021 14.8 0.1 0.052 13.5 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lycopene_cycl PF05834.12 KXZ48182.1 - 8.8e-69 232.4 2.8 1.4e-41 142.8 0.1 2.6 2 1 1 3 3 3 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXZ48182.1 - 3.9e-06 26.4 0.0 7.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXZ48182.1 - 0.00012 21.0 0.2 0.00024 19.9 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXZ48182.1 - 0.00013 21.3 0.1 0.00028 20.2 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ48182.1 - 0.00038 19.8 0.0 0.00068 18.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXZ48182.1 - 0.00049 19.8 1.7 0.0085 15.7 0.3 2.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXZ48182.1 - 0.00064 19.9 0.4 0.00064 19.9 0.4 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ48182.1 - 0.0011 18.2 0.5 0.0011 18.2 0.5 2.1 2 1 1 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 KXZ48182.1 - 0.0026 16.7 0.5 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXZ48182.1 - 0.004 16.5 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXZ48182.1 - 0.026 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXZ48182.1 - 0.13 12.3 0.5 0.7 9.9 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXZ48182.1 - 0.16 12.5 0.1 0.51 10.9 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BBL5 PF07289.11 KXZ48183.1 - 2.1e-124 414.9 0.0 2.4e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 KXZ48183.1 - 0.00064 19.9 0.1 0.0021 18.2 0.1 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 SAP PF02037.27 KXZ48184.1 - 5.4e-09 35.6 0.1 7.7e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 SAP domain COQ9 PF08511.11 KXZ48185.1 - 7.5e-28 96.1 0.2 1.2e-27 95.5 0.2 1.3 1 0 0 1 1 1 1 COQ9 FAP PF07174.11 KXZ48185.1 - 0.56 9.6 14.6 0.82 9.1 14.6 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CAP_N PF01213.19 KXZ48185.1 - 1.5 8.2 6.2 2.1 7.8 6.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3138 PF11336.8 KXZ48186.1 - 0.7 8.4 2.6 0.91 8.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) WAC_Acf1_DNA_bd PF10537.9 KXZ48187.1 - 2.8e-24 85.5 1.3 4.7e-24 84.8 0.1 2.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal RRM_1 PF00076.22 KXZ48187.1 - 2.3e-20 72.2 0.0 5.2e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 KXZ48187.1 - 9.7e-15 55.1 4.0 2.9e-14 53.5 4.0 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G HARE-HTH PF05066.13 KXZ48187.1 - 6.1e-06 26.5 0.0 2.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain RRM_occluded PF16842.5 KXZ48187.1 - 0.0073 16.1 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif Smg4_UPF3 PF03467.15 KXZ48188.1 - 7.4e-41 140.1 0.0 1.4e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_2 PF04059.12 KXZ48188.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif 2 PI-PLC-X PF00388.19 KXZ48189.1 - 6.1e-45 152.4 0.0 1e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXZ48189.1 - 2.9e-27 95.3 0.1 2.4e-26 92.3 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KXZ48189.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.7 KXZ48190.1 - 1.2e-14 54.7 7.4 4.8e-06 27.1 0.8 4.3 4 0 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48190.1 - 2.5e-09 37.5 12.2 0.0021 18.6 0.9 6.1 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48190.1 - 1.3e-05 25.3 7.1 0.1 12.9 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48190.1 - 0.56 10.8 10.1 7.4 7.2 0.1 5.3 4 1 1 5 5 5 0 Ankyrin repeat Ank_3 PF13606.6 KXZ48190.1 - 0.68 10.7 10.0 1.4e+02 3.6 0.0 6.9 9 0 0 9 9 9 0 Ankyrin repeat Homoserine_dh PF00742.19 KXZ48191.1 - 2e-53 180.9 0.0 2.4e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KXZ48191.1 - 1.1e-09 39.0 0.0 1.9e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Josephin PF02099.17 KXZ48192.1 - 2.6e-24 86.2 0.0 3.3e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Josephin NDC10_II PF16787.5 KXZ48193.1 - 1.1e-18 67.4 0.0 1.6e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RVT_1 PF00078.27 KXZ48194.1 - 0.017 14.7 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_2 PF07992.14 KXZ48195.1 - 3.7e-69 233.2 4.5 4.8e-69 232.8 4.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXZ48195.1 - 3.9e-41 139.8 0.4 8.5e-41 138.7 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXZ48195.1 - 2.4e-20 72.8 6.3 8.3e-18 64.7 0.5 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ48195.1 - 1e-09 38.1 3.7 5.9e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXZ48195.1 - 3.4e-08 33.0 7.2 4.1e-05 22.8 6.0 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXZ48195.1 - 4.3e-08 32.9 2.3 4.3e-08 32.9 2.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ48195.1 - 8.5e-07 28.4 14.3 5e-05 22.6 4.0 3.4 4 0 0 4 4 4 2 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KXZ48195.1 - 5.1e-05 22.9 3.5 0.00012 21.7 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KXZ48195.1 - 0.00021 20.7 8.5 0.001 18.4 0.3 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KXZ48195.1 - 0.00022 21.4 9.6 0.013 15.7 2.9 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXZ48195.1 - 0.00054 19.3 6.4 0.0091 15.3 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KXZ48195.1 - 0.0015 17.3 12.3 0.0049 15.6 1.4 3.9 2 1 2 4 4 4 1 HI0933-like protein Thi4 PF01946.17 KXZ48195.1 - 0.0021 17.4 5.9 0.012 14.9 0.9 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 KXZ48195.1 - 0.0064 16.4 0.2 0.0064 16.4 0.2 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KXZ48195.1 - 0.023 13.7 3.7 0.23 10.5 0.8 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXZ48195.1 - 1.8 9.0 4.4 3.4 8.2 0.1 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Adaptin_N PF01602.20 KXZ48196.1 - 2.3e-154 514.8 6.8 2.9e-154 514.5 6.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXZ48196.1 - 6e-65 218.2 4.6 1.3e-63 213.9 0.3 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KXZ48196.1 - 6.3e-15 55.2 0.0 1.5e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KXZ48196.1 - 2.5e-13 50.2 16.3 2.6e-05 24.5 0.0 6.6 3 2 4 7 7 6 5 HEAT repeats HEAT PF02985.22 KXZ48196.1 - 5.4e-09 35.5 17.3 0.0053 16.9 0.1 7.0 7 0 0 7 7 6 3 HEAT repeat CLASP_N PF12348.8 KXZ48196.1 - 2.6e-05 23.9 0.3 1.2 8.6 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal Cnd3 PF12719.7 KXZ48196.1 - 3.2e-05 23.3 0.6 0.004 16.4 0.2 2.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KXZ48196.1 - 3.4e-05 24.0 4.0 1.4 9.1 0.0 4.8 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KXZ48196.1 - 0.00051 20.0 2.1 0.91 9.7 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KXZ48196.1 - 0.0012 18.9 0.1 0.4 10.7 0.0 3.3 3 1 0 3 3 2 1 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 KXZ48196.1 - 0.0026 17.7 0.8 4.9 7.1 0.0 3.4 4 0 0 4 4 4 2 Myosin-binding striated muscle assembly central Arm_2 PF04826.13 KXZ48196.1 - 0.0035 16.8 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 Armadillo-like Xpo1 PF08389.12 KXZ48196.1 - 0.02 15.0 0.9 0.085 12.9 0.1 2.4 3 0 0 3 3 3 0 Exportin 1-like protein DUF5578 PF17741.1 KXZ48196.1 - 0.11 11.9 1.2 4.6 6.6 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 KXZ48196.1 - 0.4 11.3 11.7 3.5 8.2 0.0 6.1 6 0 0 6 6 5 0 HEAT-like repeat Ig_mannosidase PF17753.1 KXZ48197.1 - 0.0084 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain EF-hand_6 PF13405.6 KXZ48198.1 - 1.9e-09 36.7 1.1 0.0014 18.4 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KXZ48198.1 - 2e-08 34.5 0.9 3.2e-05 24.3 1.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ48198.1 - 2.1e-07 30.0 3.0 0.00025 20.4 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KXZ48198.1 - 3.8e-05 23.0 5.1 0.00013 21.3 0.4 2.7 2 0 0 2 2 2 1 EF hand NYD-SP28 PF14772.6 KXZ48198.1 - 7.2 6.7 9.6 15 5.7 9.6 1.4 1 0 0 1 1 1 0 Sperm tail zf-MYND PF01753.18 KXZ48199.1 - 7.7e-07 29.1 8.2 1.7e-06 28.0 8.2 1.6 1 0 0 1 1 1 1 MYND finger PCI PF01399.27 KXZ48200.1 - 1.7e-11 44.5 0.0 6.3e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 PCI domain ABC2_membrane PF01061.24 KXZ48202.1 - 1.1e-72 243.9 61.9 3.8e-43 147.3 26.6 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXZ48202.1 - 3.4e-36 124.8 0.0 1.4e-16 61.3 0.0 2.6 3 0 0 3 3 2 2 ABC transporter AAA_16 PF13191.6 KXZ48202.1 - 5.4e-09 36.6 0.2 6.7e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KXZ48202.1 - 2e-08 34.4 0.0 0.022 14.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_trans_N PF14510.6 KXZ48202.1 - 2.7e-08 34.3 0.0 6.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 KXZ48202.1 - 1.1e-07 32.2 1.0 0.00013 22.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXZ48202.1 - 2.2e-07 30.5 0.4 0.017 14.9 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 KXZ48202.1 - 2.5e-07 31.2 0.4 0.0002 21.8 0.0 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) PDR_assoc PF08370.11 KXZ48202.1 - 5.2e-07 29.3 1.3 6.4e-06 25.8 0.0 2.9 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_25 PF13481.6 KXZ48202.1 - 7.5e-07 28.9 0.4 0.04 13.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXZ48202.1 - 1.9e-06 27.7 0.8 0.0027 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXZ48202.1 - 3.4e-06 27.1 0.5 0.049 13.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KXZ48202.1 - 7.7e-06 26.1 0.4 0.025 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXZ48202.1 - 8.9e-06 26.0 2.1 0.02 15.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KXZ48202.1 - 1.1e-05 25.4 0.9 0.0045 16.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KXZ48202.1 - 1.7e-05 25.4 0.3 0.025 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ48202.1 - 3.4e-05 24.2 0.2 0.0067 16.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase SMC_N PF02463.19 KXZ48202.1 - 5.8e-05 22.6 0.0 3.3 7.1 0.0 4.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 KXZ48202.1 - 8.8e-05 22.5 1.6 0.0029 17.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KXZ48202.1 - 0.00035 20.6 0.2 0.31 11.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 KXZ48202.1 - 0.00038 20.5 1.1 0.19 11.7 0.1 3.0 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KXZ48202.1 - 0.00051 20.0 0.0 0.043 13.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain NTPase_1 PF03266.15 KXZ48202.1 - 0.00056 19.8 2.2 0.12 12.3 0.0 3.6 4 0 0 4 4 3 1 NTPase AAA_23 PF13476.6 KXZ48202.1 - 0.0011 19.5 0.1 0.49 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KXZ48202.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KXZ48202.1 - 0.0015 18.1 2.6 0.14 11.7 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 KXZ48202.1 - 0.0016 18.2 0.7 0.047 13.4 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Ploopntkinase3 PF18751.1 KXZ48202.1 - 0.0019 18.1 0.4 0.078 12.9 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 KXZ48202.1 - 0.0022 18.3 1.0 0.025 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KXZ48202.1 - 0.0023 17.1 8.1 0.0023 17.1 8.1 3.3 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_24 PF13479.6 KXZ48202.1 - 0.0024 17.6 4.0 0.069 12.9 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 KXZ48202.1 - 0.0027 17.2 0.8 0.019 14.5 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 KXZ48202.1 - 0.0029 17.3 2.2 0.92 9.3 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KXZ48202.1 - 0.0049 16.5 1.5 0.19 11.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_11 PF13086.6 KXZ48202.1 - 0.005 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXZ48202.1 - 0.0098 15.1 0.3 0.47 9.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 KXZ48202.1 - 0.013 15.5 0.4 0.52 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXZ48202.1 - 0.016 14.5 0.6 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KXZ48202.1 - 0.016 15.1 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KXZ48202.1 - 0.02 15.3 2.2 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXZ48202.1 - 0.023 14.1 3.3 0.24 10.7 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KXZ48202.1 - 0.032 14.0 0.3 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KXZ48202.1 - 0.039 14.2 0.3 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 KXZ48202.1 - 0.042 13.3 0.2 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DnaB_C PF03796.15 KXZ48202.1 - 0.061 12.7 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 KXZ48202.1 - 0.088 11.8 0.4 0.38 9.8 0.0 2.1 3 0 0 3 3 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KXZ48202.1 - 0.09 12.5 0.3 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 KXZ48202.1 - 0.092 12.5 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase MobB PF03205.14 KXZ48202.1 - 0.097 12.6 1.7 9.7 6.1 0.1 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 KXZ48202.1 - 0.11 12.2 0.7 0.87 9.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein CLP1_P PF16575.5 KXZ48202.1 - 0.16 11.7 0.9 0.94 9.2 0.0 2.5 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase PF06745.13 KXZ48202.1 - 0.18 11.1 0.1 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 KaiC TIP49 PF06068.13 KXZ48202.1 - 0.24 10.6 0.0 0.42 9.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Septin PF00735.18 KXZ48202.1 - 0.25 10.6 0.2 9.3 5.4 0.0 2.2 2 0 0 2 2 2 0 Septin dNK PF01712.19 KXZ48202.1 - 0.27 11.1 1.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF87 PF01935.17 KXZ48202.1 - 0.33 11.0 1.7 9.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 KXZ48205.1 - 1.5e-44 151.9 0.0 3.9e-18 66.3 0.0 4.2 3 2 2 5 5 4 3 ABC transporter ABC_tran_Xtn PF12848.7 KXZ48205.1 - 4.6e-24 84.2 3.8 4.6e-24 84.2 3.8 3.0 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KXZ48205.1 - 2.3e-15 57.2 7.9 0.00051 19.9 0.0 4.6 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ48205.1 - 2.3e-07 30.5 1.7 0.6 9.5 0.2 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXZ48205.1 - 4.5e-07 30.4 0.4 0.0074 16.7 0.2 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KXZ48205.1 - 9.5e-07 29.3 0.5 0.061 13.7 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXZ48205.1 - 1.2e-06 28.1 0.9 0.016 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KXZ48205.1 - 1.3e-06 28.4 1.2 0.12 12.1 0.2 3.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_23 PF13476.6 KXZ48205.1 - 1.6e-06 28.8 6.1 0.0083 16.6 0.2 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXZ48205.1 - 2.2e-06 27.7 0.2 0.0044 17.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KXZ48205.1 - 2.2e-06 27.5 0.6 0.026 14.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KXZ48205.1 - 4.2e-06 26.8 0.0 0.037 14.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KXZ48205.1 - 1.2e-05 25.6 4.5 0.0079 16.4 0.4 3.8 4 1 0 4 4 4 2 AAA domain AAA_13 PF13166.6 KXZ48205.1 - 2e-05 23.5 0.6 0.025 13.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KXZ48205.1 - 5e-05 23.3 0.1 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KXZ48205.1 - 6.2e-05 23.3 0.1 0.37 11.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KXZ48205.1 - 0.00027 20.7 0.0 0.98 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXZ48205.1 - 0.0012 19.3 0.3 0.41 11.2 0.0 3.6 4 0 0 4 4 2 1 AAA domain AAA_19 PF13245.6 KXZ48205.1 - 0.0024 18.2 0.3 1.3 9.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KXZ48205.1 - 0.0027 18.1 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 KXZ48205.1 - 0.0033 17.4 1.4 0.23 11.4 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_5 PF07728.14 KXZ48205.1 - 0.0038 17.2 1.3 3.5 7.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXZ48205.1 - 0.0062 16.6 0.0 4.5 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXZ48205.1 - 0.0076 15.5 0.1 2.4 7.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 KXZ48205.1 - 0.0093 16.2 0.0 3.2 8.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KXZ48205.1 - 0.0098 16.0 0.0 2.1 8.4 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 KXZ48205.1 - 0.011 16.0 6.2 1.8 8.7 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 KXZ48205.1 - 0.018 14.6 0.9 2.2 7.8 0.0 3.3 3 1 0 3 3 3 0 AAA domain Rad17 PF03215.15 KXZ48205.1 - 0.029 14.3 0.0 0.65 9.9 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain PduV-EutP PF10662.9 KXZ48205.1 - 0.03 14.1 0.1 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 KXZ48205.1 - 0.037 13.5 0.1 0.85 9.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Bacillus_HBL PF05791.11 KXZ48205.1 - 0.045 13.6 0.2 0.088 12.6 0.2 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) AAA_7 PF12775.7 KXZ48205.1 - 0.095 12.2 0.1 14 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 KXZ48205.1 - 0.098 11.4 0.2 11 4.7 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein cobW PF02492.19 KXZ48205.1 - 0.1 12.2 0.2 7 6.2 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KXZ48205.1 - 0.11 11.8 0.0 8.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Septin SRP54 PF00448.22 KXZ48205.1 - 0.11 12.1 0.4 7.9 6.1 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 KXZ48205.1 - 0.15 11.5 0.1 6.7 6.1 0.0 2.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF87 PF01935.17 KXZ48205.1 - 0.19 11.8 2.0 5.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain FeoB_N PF02421.18 KXZ48205.1 - 0.21 11.1 0.1 7.9 6.0 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ZapB PF06005.12 KXZ48205.1 - 1.2 9.6 4.9 0.65 10.5 0.3 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DUF3584 PF12128.8 KXZ48205.1 - 3.8 4.9 6.9 13 3.1 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Ank_2 PF12796.7 KXZ48206.1 - 8.7e-100 327.5 16.8 4.1e-17 62.5 0.1 9.1 3 3 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ48206.1 - 5.7e-85 276.4 41.8 1.8e-06 28.2 0.2 17.5 18 0 0 18 18 18 15 Ankyrin repeat Ank_4 PF13637.6 KXZ48206.1 - 1.8e-83 273.9 9.7 2.9e-11 43.7 0.0 10.1 8 1 2 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48206.1 - 4.8e-78 247.7 14.3 0.00026 21.2 0.0 17.4 17 0 0 17 17 17 15 Ankyrin repeat Ank_5 PF13857.6 KXZ48206.1 - 4.1e-71 234.1 35.0 7e-08 32.6 0.0 15.7 6 6 10 16 16 16 15 Ankyrin repeats (many copies) AnkUBD PF18418.1 KXZ48206.1 - 0.00034 20.7 0.3 51 4.1 0.0 6.4 6 2 2 8 8 8 0 Ankyrin ubiquitin-binding domain SBP_bac_1 PF01547.25 KXZ48206.1 - 0.00062 19.8 1.9 0.35 10.8 0.0 2.8 3 0 0 3 3 3 2 Bacterial extracellular solute-binding protein Ank_2 PF12796.7 KXZ48207.1 - 1.8e-06 28.4 0.3 0.22 12.1 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48207.1 - 0.00013 22.4 5.2 8 7.2 0.0 6.2 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Defensin_4 PF07936.12 KXZ48207.1 - 0.53 10.2 2.4 69 3.5 0.0 4.0 4 0 0 4 4 4 0 Potassium-channel blocking toxin DUF4281 PF14108.6 KXZ48208.1 - 5.9e-24 84.8 5.6 7.2e-24 84.6 5.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) HK PF02110.15 KXZ48209.1 - 1.8e-59 201.1 6.3 2.1e-59 200.9 6.3 1.1 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KXZ48209.1 - 0.015 14.8 1.0 0.024 14.1 1.0 1.4 1 0 0 1 1 1 0 Carbohydrate kinase ESX-1_EspG PF14011.6 KXZ48209.1 - 0.04 13.5 6.4 0.022 14.4 4.2 1.7 1 1 0 1 1 1 0 EspG family CDC27 PF09507.10 KXZ48210.1 - 0.94 8.8 6.2 1.6 8.1 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_6 PF12774.7 KXZ48211.1 - 1.5e-161 536.8 0.2 2.4e-158 526.3 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ48211.1 - 9.2e-128 426.7 0.0 2.2e-127 425.5 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXZ48211.1 - 3.8e-118 394.2 0.0 2.6e-91 306.0 0.0 3.5 2 1 1 3 3 3 2 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KXZ48211.1 - 2.3e-101 338.5 0.1 7.8e-101 336.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXZ48211.1 - 2.9e-89 297.9 0.3 7.4e-89 296.6 0.3 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ48211.1 - 2e-83 278.4 0.1 2.8e-81 271.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ48211.1 - 2.5e-59 199.7 0.0 6.1e-59 198.5 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXZ48211.1 - 4.2e-56 190.4 4.6 4.2e-56 190.4 4.6 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KXZ48211.1 - 8.1e-35 119.7 0.0 2.1e-34 118.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXZ48211.1 - 2.9e-30 104.8 0.1 8.3e-20 71.1 0.0 3.9 2 1 1 3 3 3 2 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 KXZ48211.1 - 4.3e-15 55.7 0.0 2e-14 53.6 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ48211.1 - 1.7e-13 50.7 0.0 0.006 16.6 0.0 5.4 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 KXZ48211.1 - 3.9e-06 27.3 0.0 0.28 11.6 0.0 3.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ48211.1 - 0.0044 17.3 0.7 2.4 8.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KXZ48211.1 - 0.0058 17.0 0.3 7.9 6.8 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.6 KXZ48211.1 - 0.014 15.5 0.1 0.52 10.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXZ48211.1 - 0.018 14.1 0.1 0.097 11.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 KXZ48211.1 - 0.02 15.4 0.0 0.28 11.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXZ48211.1 - 0.052 13.3 0.1 21 4.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXZ48211.1 - 0.077 13.4 0.0 31 5.0 0.0 3.1 2 0 0 2 2 2 0 RNA helicase DUF853 PF05872.12 KXZ48211.1 - 0.087 11.4 0.6 2 6.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF4349 PF14257.6 KXZ48211.1 - 6.2 6.2 8.2 0.16 11.4 0.4 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4349) Cyt-b5 PF00173.28 KXZ48212.1 - 1.5e-07 31.5 0.0 1.8e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cupin_8 PF13621.6 KXZ48213.1 - 3.5e-15 56.4 0.0 4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JAB PF01398.21 KXZ48214.1 - 1.5e-26 92.7 0.0 2.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KXZ48214.1 - 2.8e-09 36.8 0.2 6.5e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain BRCC36_C PF18110.1 KXZ48214.1 - 2.3e-08 34.1 0.0 4.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain UPF0172 PF03665.13 KXZ48214.1 - 0.035 14.2 0.0 0.08 13.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Hemerythrin PF01814.23 KXZ48214.1 - 0.42 11.2 3.9 0.24 12.0 1.5 1.8 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF5527 PF17665.1 KXZ48215.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Ribosomal_60s PF00428.19 KXZ48215.1 - 9.9 6.8 9.9 6.2 7.5 7.5 1.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein Pax2_C PF12403.8 KXZ48216.1 - 0.055 13.5 1.7 0.078 13.1 1.7 1.3 1 0 0 1 1 1 0 Paired-box protein 2 C terminal DUF2946 PF11162.8 KXZ48216.1 - 0.13 12.9 6.1 0.21 12.3 6.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Ldt_C PF17969.1 KXZ48217.1 - 1.7e-05 25.4 1.4 11 6.8 0.0 4.9 4 1 1 5 5 5 3 L,D-transpeptidase C-terminal domain Pap_E4 PF02711.14 KXZ48217.1 - 1.5 9.8 25.1 5.5 8.0 0.2 5.7 2 2 6 8 8 8 0 E4 protein Tyrosinase PF00264.20 KXZ48217.1 - 2.4 8.4 7.3 22 5.2 0.6 3.1 1 1 2 3 3 3 0 Common central domain of tyrosinase IF2_assoc PF08364.11 KXZ48217.1 - 2.6 8.4 11.6 15 5.9 0.2 4.6 4 0 0 4 4 4 0 Bacterial translation initiation factor IF-2 associated region DUF3644 PF12358.8 KXZ48217.1 - 2.7 8.6 6.7 52 4.4 0.1 4.2 3 2 2 5 5 5 0 Protein of unknown function (DUF3644) DUF1173 PF06666.11 KXZ48217.1 - 3.8 6.3 6.8 27 3.6 0.0 3.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1173) Mucin PF01456.17 KXZ48218.1 - 0.0081 16.2 1.2 0.0092 16.0 0.4 1.5 2 0 0 2 2 2 1 Mucin-like glycoprotein OsmC PF02566.19 KXZ48219.1 - 0.016 15.6 0.4 0.05 14.1 0.0 1.9 2 1 0 2 2 2 0 OsmC-like protein Pap_E4 PF02711.14 KXZ48219.1 - 1.4 9.9 10.5 0.26 12.3 1.8 2.8 2 1 1 3 3 3 0 E4 protein Tir_receptor_C PF07489.11 KXZ48219.1 - 4.2 7.3 14.2 2.7 7.9 11.1 1.9 1 1 1 2 2 2 0 Translocated intimin receptor (Tir) C-terminus TFIIB PF00382.19 KXZ48221.1 - 1.6e-25 88.9 7.4 1.9e-13 50.3 0.0 3.8 4 0 0 4 4 4 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KXZ48221.1 - 1.7e-23 82.9 0.8 1.7e-23 82.9 0.8 3.0 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_C PF02984.19 KXZ48221.1 - 0.018 15.1 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Cyclin, C-terminal domain TF_Zn_Ribbon PF08271.12 KXZ48221.1 - 0.09 12.3 3.6 0.23 11.0 3.6 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KXZ48221.1 - 1.1 9.6 3.1 2.4 8.5 3.1 1.6 1 0 0 1 1 1 0 zinc-ribbon Utp14 PF04615.13 KXZ48222.1 - 2.7e-156 522.3 34.1 4.4e-100 336.4 23.2 4.9 4 1 0 4 4 4 2 Utp14 protein PAP_fibrillin PF04755.12 KXZ48222.1 - 1.2e-19 71.1 0.0 7.1e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 PAP_fibrillin Apis_Csd PF11671.8 KXZ48222.1 - 8.9 6.3 8.0 1.1 9.3 3.3 1.9 2 0 0 2 2 2 0 Complementary sex determiner protein ZapD PF07072.11 KXZ48223.1 - 0.052 13.3 3.2 0.091 12.5 3.2 1.4 1 0 0 1 1 1 0 Cell division protein APG6_N PF17675.1 KXZ48223.1 - 0.36 11.4 5.9 0.66 10.5 5.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KXZ48223.1 - 0.98 9.7 5.7 2 8.7 5.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rho_N PF07498.12 KXZ48224.1 - 0.074 13.0 0.5 0.097 12.6 0.5 1.2 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain CIAPIN1 PF05093.13 KXZ48225.1 - 2.8e-19 69.5 16.5 2.4e-16 60.1 1.9 2.6 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_23 PF13489.6 KXZ48225.1 - 0.0044 16.9 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ48225.1 - 0.029 13.7 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DRE2_N PF16803.5 KXZ48225.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Guanylate_cyc PF00211.20 KXZ48227.1 - 3e-32 111.7 0.0 1.7e-28 99.5 0.2 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain TipAS PF07739.13 KXZ48228.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain FKBP_C PF00254.28 KXZ48229.1 - 1.7e-18 66.7 0.0 2.4e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cytomega_UL20A PF05984.12 KXZ48229.1 - 0.072 13.4 0.0 0.087 13.1 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Ammonium_transp PF00909.21 KXZ48230.1 - 1.1e-53 182.5 25.9 1.5e-53 182.0 25.9 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DEAD PF00270.29 KXZ48231.1 - 2e-14 53.8 0.0 3.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ48231.1 - 4e-06 27.1 0.0 7.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ48231.1 - 2e-05 24.7 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KXZ48231.1 - 0.035 13.7 0.2 0.59 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sporozoite_P67 PF05642.11 KXZ48231.1 - 3.5 5.6 6.0 11 3.9 0.2 2.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen rve PF00665.26 KXZ48232.1 - 1.4e-15 57.5 0.0 2.4e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain PHD PF00628.29 KXZ48232.1 - 9.9e-12 44.6 1.7 1.8e-11 43.8 1.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXZ48232.1 - 0.062 12.9 0.5 0.14 11.8 0.5 1.6 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KXZ48232.1 - 0.1 12.9 1.0 0.29 11.5 0.2 2.0 2 0 0 2 2 2 0 C1 domain zf-PHD-like PF15446.6 KXZ48232.1 - 0.11 12.1 0.7 0.19 11.3 0.7 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 KXZ48232.1 - 2.1 8.8 5.4 6 7.3 5.4 1.8 1 0 0 1 1 1 0 Ring finger domain MIP-T3 PF10243.9 KXZ48233.1 - 5.5e-38 129.4 0.0 1e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 KXZ48233.1 - 1.9e-25 89.6 0.1 1.9e-25 89.6 0.1 2.3 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Plasmodium_Vir PF05795.11 KXZ48233.1 - 0.048 13.1 1.7 0.08 12.4 1.7 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ANAPC4 PF12896.7 KXZ48233.1 - 0.17 11.3 0.2 0.29 10.6 0.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 RR_TM4-6 PF06459.12 KXZ48233.1 - 5.9 6.6 13.3 11 5.7 13.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vinculin PF01044.19 KXZ48233.1 - 9.7 4.3 7.9 17 3.5 7.9 1.4 1 0 0 1 1 1 0 Vinculin family PsbW PF07123.12 KXZ48235.1 - 1.8e-24 86.3 0.0 1.9e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Photosystem II reaction centre W protein (PsbW) Arm PF00514.23 KXZ48236.1 - 8.8e-05 22.4 7.3 1.4 9.1 0.6 5.7 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Phage_min_cap2 PF06152.11 KXZ48236.1 - 0.31 9.9 0.0 0.31 9.9 0.0 1.9 2 0 0 2 2 2 0 Phage minor capsid protein 2 Exo_endo_phos PF03372.23 KXZ48237.1 - 1.4e-05 24.8 0.0 4.7e-05 23.0 0.0 1.9 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Big_4 PF07532.11 KXZ48238.1 - 0.13 12.1 0.1 0.52 10.1 0.0 1.9 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 4) Lig_chan PF00060.26 KXZ48239.1 - 4.4e-18 65.5 0.0 6.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KXZ48239.1 - 5.5e-06 26.0 0.0 1.2e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ni_hydr_CYTB PF01292.20 KXZ48239.1 - 0.13 11.8 1.6 0.26 10.9 0.3 1.8 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Cofac_haem_bdg PF04187.13 KXZ48240.1 - 5.6e-36 124.5 0.1 1.2e-35 123.5 0.1 1.5 1 1 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN Aldolase_II PF00596.21 KXZ48241.1 - 0.032 14.2 0.0 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain DnaJ_CXXCXGXG PF00684.19 KXZ48242.1 - 4.6e-05 23.7 9.7 0.00016 21.9 10.0 1.9 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXZ48242.1 - 0.0024 17.8 0.9 0.0024 17.8 0.9 3.2 1 1 2 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 KXZ48242.1 - 0.012 15.9 3.5 0.035 14.5 3.5 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.12 KXZ48242.1 - 4.5 7.6 17.9 7.3 7.0 15.3 2.8 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase SET PF00856.28 KXZ48243.1 - 4.8e-19 69.4 0.1 4.8e-19 69.4 0.1 3.1 3 0 0 3 3 3 1 SET domain GYF_2 PF14237.6 KXZ48243.1 - 0.018 14.8 0.2 25 4.8 0.0 3.8 4 0 0 4 4 4 0 GYF domain 2 Exo_endo_phos PF03372.23 KXZ48244.1 - 9.2e-26 90.8 0.0 1.4e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXZ48244.1 - 0.048 13.5 0.4 8.2 6.3 0.0 2.9 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase zf-RING_11 PF17123.5 KXZ48245.1 - 2.4e-08 33.6 6.2 4.5e-08 32.7 6.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXZ48245.1 - 1.1e-06 28.8 5.5 2.6e-06 27.6 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ48245.1 - 0.00016 21.4 5.2 0.00032 20.5 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ48245.1 - 0.004 17.0 6.9 0.0085 15.9 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 KXZ48245.1 - 0.02 15.0 1.1 0.042 14.0 1.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.6 KXZ48245.1 - 0.024 14.6 6.2 0.058 13.4 6.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KXZ48245.1 - 0.041 14.2 2.3 0.11 12.7 2.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXZ48245.1 - 0.23 11.5 5.3 0.51 10.4 5.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DHC_N1 PF08385.12 KXZ48246.1 - 4.4e-180 600.0 21.0 4.4e-180 600.0 21.0 4.1 5 2 1 7 7 7 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KXZ48246.1 - 3.2e-150 499.6 0.1 9.3e-149 494.8 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ48246.1 - 3.3e-121 405.2 12.9 3.3e-121 405.2 12.9 5.0 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXZ48246.1 - 4.2e-94 314.7 0.0 3e-92 308.6 0.0 3.4 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXZ48246.1 - 3.2e-86 288.0 2.8 1.3e-85 286.0 2.1 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 KXZ48246.1 - 1.2e-83 280.9 0.0 7.4e-83 278.3 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KXZ48246.1 - 1.3e-61 207.3 1.6 3.2e-56 189.7 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ48246.1 - 1.5e-54 184.3 0.0 3.9e-54 182.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXZ48246.1 - 6.1e-52 176.7 18.0 1.7e-51 175.3 18.0 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXZ48246.1 - 1.9e-40 137.6 0.0 3e-38 130.6 0.0 3.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KXZ48246.1 - 2.5e-21 76.1 0.0 3.1e-09 36.9 0.0 5.8 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KXZ48246.1 - 4.8e-21 75.2 0.3 6.3e-20 71.6 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ48246.1 - 9.4e-16 57.9 0.3 4.4e-14 52.5 0.1 3.8 2 1 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 KXZ48246.1 - 1.7e-11 44.7 0.1 0.031 14.7 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ48246.1 - 2.2e-06 28.1 3.6 0.069 13.5 0.0 6.5 6 0 0 6 6 6 1 AAA ATPase domain AAA_18 PF13238.6 KXZ48246.1 - 3.3e-05 24.4 1.3 0.36 11.4 0.0 4.6 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 KXZ48246.1 - 0.00048 20.4 5.7 0.59 10.4 0.0 5.0 6 0 0 6 6 4 1 AAA domain Mg_chelatase PF01078.21 KXZ48246.1 - 0.00062 19.2 0.4 0.041 13.3 0.0 3.5 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXZ48246.1 - 0.0014 19.0 0.8 1.7 9.1 0.0 4.4 4 0 0 4 4 3 1 RNA helicase AAA_19 PF13245.6 KXZ48246.1 - 0.0018 18.6 8.8 0.41 11.0 0.1 5.6 6 0 0 6 6 4 1 AAA domain AAA_28 PF13521.6 KXZ48246.1 - 0.004 17.4 2.1 2.1 8.6 0.0 4.8 5 0 0 5 5 5 1 AAA domain AAA_29 PF13555.6 KXZ48246.1 - 0.023 14.4 0.6 0.88 9.4 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KXZ48246.1 - 0.037 14.2 4.1 0.55 10.4 0.0 4.4 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.6 KXZ48246.1 - 0.057 13.9 0.0 0.057 13.9 0.0 6.7 6 1 0 6 6 3 0 AAA domain Swi6_N PF18530.1 KXZ48246.1 - 0.062 13.4 0.0 0.27 11.4 0.0 2.2 1 0 0 1 1 1 0 Swi6 N-terminal domain AAA_24 PF13479.6 KXZ48246.1 - 0.21 11.3 1.4 15 5.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KXZ48246.1 - 0.53 10.0 2.6 0.99 9.1 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein Glu_cyclase_2 PF05096.12 KXZ48248.1 - 4.6e-21 75.4 0.1 5.6e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase Glu_cyclase_2 PF05096.12 KXZ48249.1 - 5.1e-33 114.6 0.4 6.2e-33 114.3 0.4 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase Arylesterase PF01731.20 KXZ48249.1 - 0.046 13.9 0.0 0.22 11.7 0.0 1.9 2 1 0 2 2 2 0 Arylesterase SBP PF03110.14 KXZ48251.1 - 6.7e-09 35.9 6.4 7.4e-09 35.8 5.6 1.5 1 1 0 1 1 1 1 SBP domain Pardaxin PF07425.11 KXZ48251.1 - 0.11 12.2 0.9 0.21 11.2 0.9 1.5 1 0 0 1 1 1 0 Pardaxin Keratin_2_head PF16208.5 KXZ48252.1 - 0.016 15.4 4.0 0.021 15.0 4.0 1.2 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.8 KXZ48252.1 - 1.1 9.8 9.2 2.6 8.7 9.3 1.7 1 1 0 1 1 1 0 Keratin-associated matrix TFIIA PF03153.13 KXZ48255.1 - 0.019 15.0 7.2 0.02 14.9 7.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.19 KXZ48255.1 - 0.084 13.4 3.8 0.11 13.1 3.8 1.2 1 0 0 1 1 1 0 Dehydrin Pex14_N PF04695.13 KXZ48255.1 - 0.11 13.2 5.8 0.14 12.8 5.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PIEZO PF15917.5 KXZ48255.1 - 0.16 11.4 4.7 0.21 11.1 4.7 1.1 1 0 0 1 1 1 0 Piezo DivIC PF04977.15 KXZ48255.1 - 0.36 10.6 6.7 0.6 9.9 6.7 1.3 1 0 0 1 1 1 0 Septum formation initiator FAM199X PF15814.5 KXZ48255.1 - 0.57 9.2 6.8 0.78 8.7 6.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X PepSY_2 PF13670.6 KXZ48255.1 - 3.4 7.7 9.1 0.56 10.3 4.7 1.9 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain Spt20 PF12090.8 KXZ48255.1 - 3.6 7.1 10.6 4.5 6.8 10.6 1.1 1 0 0 1 1 1 0 Spt20 family SBP PF03110.14 KXZ48256.1 - 1.7e-26 92.3 9.1 2.9e-26 91.6 9.1 1.4 1 0 0 1 1 1 1 SBP domain BTB PF00651.31 KXZ48256.1 - 7.3e-13 48.7 0.0 1.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain ATPase_2 PF01637.18 KXZ48257.1 - 0.0075 16.2 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA12 PF10443.9 KXZ48257.1 - 0.012 14.3 0.0 0.096 11.4 0.0 1.9 1 1 1 2 2 2 0 RNA12 protein DUF3138 PF11336.8 KXZ48258.1 - 0.0025 16.5 0.6 0.0025 16.5 0.6 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF3138) MCC-bdg_PDZ PF10506.9 KXZ48258.1 - 0.059 13.4 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Spc29 PF17082.5 KXZ48258.1 - 0.19 11.5 0.0 0.72 9.6 0.0 1.9 3 0 0 3 3 3 0 Spindle Pole Component 29 AAA_22 PF13401.6 KXZ48259.1 - 1.6e-07 31.6 0.0 3.1e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXZ48259.1 - 1.7e-05 24.9 0.0 7.3e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KXZ48259.1 - 0.00015 21.8 0.0 0.05 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXZ48259.1 - 0.00017 22.0 0.1 0.00042 20.7 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KXZ48259.1 - 0.042 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KXZ48259.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 KXZ48259.1 - 0.11 13.0 0.0 1.1 9.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KXZ48259.1 - 0.12 11.8 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein Rad17 PF03215.15 KXZ48259.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Tom22 PF04281.13 KXZ48260.1 - 0.39 10.5 0.5 0.68 9.7 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF4817 PF16087.5 KXZ48262.1 - 0.0014 18.4 0.1 0.05 13.4 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain (DUF4817) FeS PF04060.13 KXZ48262.1 - 0.016 14.9 0.1 0.016 14.9 0.1 1.7 2 0 0 2 2 2 0 Putative Fe-S cluster Hist_deacetyl PF00850.19 KXZ48263.1 - 9.6e-25 87.7 0.1 9.6e-25 87.7 0.1 1.8 2 0 0 2 2 2 1 Histone deacetylase domain Ank_2 PF12796.7 KXZ48263.1 - 3.8e-16 59.4 7.1 6.2e-06 26.7 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48263.1 - 6.1e-12 44.6 1.4 0.025 15.1 0.1 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXZ48263.1 - 2.6e-11 43.8 2.4 0.021 15.4 0.0 5.3 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48263.1 - 1.5e-10 41.0 8.4 0.0098 16.3 0.8 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ48263.1 - 3.6e-08 33.5 7.0 0.16 12.3 0.2 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) HEAT PF02985.22 KXZ48264.1 - 3e-45 148.3 23.9 0.0019 18.3 0.0 13.8 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KXZ48264.1 - 2e-37 127.5 9.7 9.5e-07 29.1 0.1 8.7 1 1 7 9 9 9 9 HEAT repeats HEAT_EZ PF13513.6 KXZ48264.1 - 2.7e-12 46.9 13.2 0.0075 16.8 0.1 8.4 8 2 2 10 10 10 3 HEAT-like repeat Cnd1 PF12717.7 KXZ48264.1 - 7.8e-10 39.0 7.7 0.0066 16.5 0.3 5.0 1 1 4 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXZ48264.1 - 2.4e-09 37.7 4.5 0.19 12.3 0.0 6.8 1 1 5 8 8 8 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KXZ48264.1 - 1.6e-08 33.6 4.0 0.027 13.1 0.0 3.8 1 1 2 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.8 KXZ48264.1 - 1.1e-07 31.6 0.1 0.069 12.7 0.0 3.3 1 1 2 3 3 3 3 CLASP N terminal DNA_alkylation PF08713.11 KXZ48264.1 - 0.0028 17.4 0.3 3.4 7.3 0.0 3.6 2 2 1 3 3 3 1 DNA alkylation repair enzyme Arm PF00514.23 KXZ48264.1 - 0.0041 17.1 3.9 24 5.1 0.0 6.4 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KXZ48264.1 - 0.0054 17.0 0.0 6.3 7.2 0.0 3.3 2 1 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain IFRD PF05004.13 KXZ48264.1 - 0.021 13.9 0.3 3.4 6.7 0.1 3.1 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Nefa_Nip30_N PF10187.9 KXZ48265.1 - 5.3e-05 23.5 0.5 0.0001 22.6 0.5 1.5 1 1 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Peptidase_C98 PF15499.6 KXZ48266.1 - 0.006 16.1 0.1 0.006 16.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase P_gingi_FimA PF06321.11 KXZ48266.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Major fimbrial subunit protein (FimA) Nefa_Nip30_N PF10187.9 KXZ48267.1 - 0.00016 21.9 0.1 0.00016 21.9 0.1 1.7 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 API5 PF05918.11 KXZ48267.1 - 6.4 5.5 6.6 7.4 5.2 6.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.32 KXZ48268.1 - 2e-15 56.9 1.2 0.00028 21.6 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ48268.1 - 5.1e-11 42.7 0.0 0.036 14.4 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXZ48268.1 - 0.00029 19.6 0.0 0.38 9.4 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Formyl_trans_C PF02911.18 KXZ48268.1 - 0.093 13.0 0.0 0.73 10.1 0.0 2.3 2 1 0 2 2 2 0 Formyl transferase, C-terminal domain NYN PF01936.18 KXZ48269.1 - 0.0007 20.1 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 NYN domain DUF3873 PF12989.7 KXZ48269.1 - 0.038 14.4 0.0 2.5 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3873) Alpha_kinase PF02816.18 KXZ48271.1 - 4.8e-34 118.1 0.1 6.6e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family PUB PF09409.10 KXZ48271.1 - 0.00021 21.2 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 PUB domain NatB_MDM20 PF09797.9 KXZ48272.1 - 4.1e-38 131.3 0.0 7.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KXZ48272.1 - 7.8e-05 23.1 0.2 7.8e-05 23.1 0.2 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ48272.1 - 0.42 11.6 0.0 0.064 14.1 2.2 10.8 7 3 4 11 11 11 0 Tetratricopeptide repeat TRP PF06011.12 KXZ48273.1 - 0.00018 20.4 0.7 0.00027 19.8 0.7 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Chlam_PMP PF02415.17 KXZ48273.1 - 0.041 14.4 33.0 0.38 11.3 0.2 8.8 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4149 PF13664.6 KXZ48274.1 - 2.2e-23 82.5 5.6 2.2e-23 82.5 5.6 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) Phage_holin_2_4 PF16082.5 KXZ48274.1 - 3 7.6 5.4 0.41 10.4 0.6 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF3439 PF11921.8 KXZ48274.1 - 8.6 6.4 16.3 13 5.8 14.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) zf-C3HC4_3 PF13920.6 KXZ48275.1 - 1.5e-09 37.6 1.6 3e-09 36.6 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KIAA1430 PF13879.6 KXZ48277.1 - 2.6e-07 31.3 0.0 7.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 KIAA1430 homologue Med20 PF08612.11 KXZ48278.1 - 3.8e-05 23.1 0.0 5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex zf-MYND PF01753.18 KXZ48280.1 - 2.1e-07 30.9 6.9 4.7e-07 29.8 6.9 1.6 1 0 0 1 1 1 1 MYND finger Kinesin PF00225.23 KXZ48281.1 - 5.6e-84 281.9 0.0 7.3e-35 120.5 0.0 3.4 3 0 0 3 3 3 3 Kinesin motor domain Ank_2 PF12796.7 KXZ48281.1 - 1.1e-19 70.7 2.3 1.1e-10 42.0 0.8 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48281.1 - 6e-19 68.2 1.2 3.4e-09 37.1 0.4 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Microtub_bd PF16796.5 KXZ48281.1 - 2.4e-18 66.5 0.0 4.5e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Ank PF00023.30 KXZ48281.1 - 5.6e-16 58.2 2.5 0.00015 22.0 0.2 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ48281.1 - 2.2e-15 56.5 1.5 7.2e-07 29.4 0.2 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48281.1 - 7.2e-14 50.6 0.5 0.0014 18.9 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat CENP-H PF05837.12 KXZ48281.1 - 0.012 16.0 4.4 0.012 16.0 4.4 7.7 3 1 4 7 7 7 0 Centromere protein H (CENP-H) SNase PF00565.17 KXZ48282.1 - 5.4e-54 181.3 0.1 4.5e-12 46.4 0.0 5.8 6 1 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KXZ48282.1 - 1.2e-25 89.9 0.0 2.4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KXZ48282.1 - 2.6e-05 24.6 0.4 0.18 12.3 0.1 3.6 3 0 0 3 3 3 2 Agenet domain SMN PF06003.12 KXZ48282.1 - 0.0073 15.6 0.0 0.023 14.0 0.0 1.8 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF1325 PF07039.11 KXZ48282.1 - 0.0083 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain ANAPC4_WD40 PF12894.7 KXZ48283.1 - 2.6e-10 40.5 3.5 3.6e-05 24.0 0.0 5.8 3 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXZ48283.1 - 1e-05 24.8 1.3 0.0037 16.4 0.0 3.6 4 0 0 4 4 4 2 Coatomer WD associated region WD40 PF00400.32 KXZ48283.1 - 0.00018 22.2 0.6 5.5 8.0 0.0 4.9 5 1 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 KXZ48283.1 - 0.0017 18.2 0.2 0.14 12.0 0.1 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A TPR_12 PF13424.6 KXZ48283.1 - 0.026 14.8 8.5 0.041 14.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 KXZ48283.1 - 0.061 13.2 5.5 0.33 10.8 0.1 4.0 4 1 1 5 5 5 0 Region in Clathrin and VPS TPR_1 PF00515.28 KXZ48283.1 - 1.3 8.9 9.0 51 3.9 2.8 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-P11 PF03854.14 KXZ48283.1 - 1.6 8.4 4.7 0.81 9.4 0.7 2.6 3 0 0 3 3 3 0 P-11 zinc finger TPR_7 PF13176.6 KXZ48283.1 - 1.8 8.8 4.0 37 4.7 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat DivIC PF04977.15 KXZ48284.1 - 1.3 8.9 6.3 0.19 11.5 1.2 2.1 2 1 0 3 3 3 0 Septum formation initiator DUF4140 PF13600.6 KXZ48284.1 - 2.6 8.5 9.2 0.29 11.6 2.8 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADP_ribosyl_GH PF03747.14 KXZ48285.1 - 4.7e-34 118.4 7.0 4.7e-34 118.4 7.0 5.9 2 1 2 4 4 4 1 ADP-ribosylglycohydrolase SnoaL_2 PF12680.7 KXZ48286.1 - 4.4e-10 40.1 0.3 9.9e-10 39.0 0.3 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXZ48286.1 - 0.0079 16.0 0.0 0.61 9.9 0.0 2.1 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase HhH-GPD PF00730.25 KXZ48287.1 - 0.00011 22.6 0.0 0.00019 21.9 0.0 1.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Kinesin PF00225.23 KXZ48288.1 - 2.9e-65 220.4 0.0 2.9e-33 115.2 0.0 2.5 2 0 0 2 2 2 2 Kinesin motor domain Ank_2 PF12796.7 KXZ48288.1 - 1.7e-21 76.6 6.5 2e-10 41.1 0.2 3.9 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48288.1 - 7.3e-16 58.3 0.9 1.2e-08 35.3 0.4 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48288.1 - 2.9e-14 52.8 6.4 4.6e-05 23.7 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ48288.1 - 9.8e-14 51.2 0.5 3.4e-09 36.8 0.3 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48288.1 - 1e-09 37.8 0.2 0.033 14.7 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat SOGA PF11365.8 KXZ48288.1 - 0.015 16.4 0.4 0.015 16.4 0.4 5.9 4 1 2 6 6 6 0 Protein SOGA Kinesin PF00225.23 KXZ48289.1 - 6.3e-67 225.9 2.1 2.5e-56 191.0 0.0 2.5 1 1 1 2 2 2 2 Kinesin motor domain Ank_5 PF13857.6 KXZ48289.1 - 1.1e-14 54.2 0.2 2.4e-08 34.1 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48289.1 - 1.6e-11 44.1 0.0 7.6e-06 26.1 0.0 3.1 3 0 0 3 3 2 2 Ankyrin repeat Ank_3 PF13606.6 KXZ48289.1 - 6.4e-11 41.5 0.0 4.6e-05 23.5 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXZ48289.1 - 7.3e-11 42.5 0.0 3.3e-10 40.4 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48289.1 - 3.9e-10 40.0 0.0 7.8e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Microtub_bd PF16796.5 KXZ48289.1 - 5.5e-08 32.9 0.4 3.3e-07 30.3 0.4 2.2 1 1 0 1 1 1 1 Microtubule binding JIP_LZII PF16471.5 KXZ48289.1 - 0.1 12.8 3.9 0.73 10.0 1.3 3.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 KXZ48289.1 - 0.24 11.6 4.0 0.44 10.8 1.7 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Adaptin_binding PF10199.9 KXZ48289.1 - 1.1 9.9 8.5 0.12 13.0 1.3 2.6 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 bZIP_1 PF00170.21 KXZ48289.1 - 1.1 9.4 8.3 0.061 13.4 0.8 2.9 2 0 0 2 2 2 0 bZIP transcription factor SOGA PF11365.8 KXZ48289.1 - 2.1 9.5 8.5 0.71 11.0 2.3 3.0 2 1 0 2 2 2 0 Protein SOGA MIB_HERC2 PF06701.13 KXZ48290.1 - 2e-07 31.2 2.8 3.3e-07 30.4 2.8 1.4 1 0 0 1 1 1 1 Mib_herc2 Fez1 PF06818.15 KXZ48290.1 - 0.064 13.7 2.0 0.11 12.9 2.0 1.3 1 0 0 1 1 1 0 Fez1 CALM_bind PF16025.5 KXZ48290.1 - 0.22 12.0 8.7 1.1 9.7 0.2 2.8 3 0 0 3 3 3 0 Calcium-dependent calmodulin binding ERM PF00769.19 KXZ48290.1 - 4.7 7.0 14.2 8.2 6.2 14.2 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Pkinase PF00069.25 KXZ48291.1 - 5e-53 180.2 0.0 3.1e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48291.1 - 2.5e-22 79.4 0.0 7e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Form_Nir_trans PF01226.17 KXZ48292.1 - 5e-63 212.6 22.4 5.9e-63 212.4 22.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2427 PF10348.9 KXZ48292.1 - 0.84 9.5 8.4 8.4 6.2 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF2427) Cornifin PF02389.15 KXZ48293.1 - 0.0081 16.4 0.1 0.0081 16.4 0.1 2.1 2 0 0 2 2 2 1 Cornifin (SPRR) family Acetyltransf_1 PF00583.25 KXZ48294.1 - 3.5e-09 36.9 0.2 3.8e-09 36.8 0.2 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ48294.1 - 8.6e-05 22.5 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ48294.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXZ48294.1 - 0.00086 19.7 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXZ48294.1 - 0.001 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ48294.1 - 0.051 13.7 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 KXZ48294.1 - 0.062 13.0 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ GAS PF13851.6 KXZ48295.1 - 1.1e-82 276.2 26.6 1.1e-82 276.2 26.6 3.3 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Ribosomal_L25p PF01386.19 KXZ48295.1 - 0.12 12.9 4.3 10 6.7 0.2 3.2 3 1 0 3 3 3 0 Ribosomal L25p family Baculo_PEP_C PF04513.12 KXZ48295.1 - 0.97 9.5 19.5 2 8.4 2.6 3.9 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_53 PF18606.1 KXZ48295.1 - 1.2 8.8 3.6 0.87 9.3 0.5 2.4 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain DUF4172 PF13776.6 KXZ48295.1 - 3.7 7.9 6.9 7 7.1 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4172) Ribosomal_L27A PF00828.19 KXZ48296.1 - 3.1e-13 50.5 0.0 4.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ank_2 PF12796.7 KXZ48297.1 - 4.3e-07 30.4 2.9 0.00095 19.7 0.0 4.3 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48297.1 - 6e-07 29.9 9.8 0.48 11.1 0.1 7.5 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48297.1 - 0.013 16.0 7.3 2.9e+02 2.6 0.0 7.5 7 1 1 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ48297.1 - 0.013 15.8 8.0 4.6 7.7 0.0 5.8 5 1 1 6 6 6 0 Ankyrin repeats (many copies) DUF2695 PF10905.8 KXZ48297.1 - 0.11 12.7 0.4 0.6 10.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) NAD_binding_1 PF00175.21 KXZ48298.1 - 3.7e-26 91.9 0.0 5.9e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 KXZ48298.1 - 0.0036 16.9 0.0 0.46 10.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_6 PF00970.24 KXZ48298.1 - 0.013 15.8 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Kinesin PF00225.23 KXZ48299.1 - 1.4e-93 313.5 0.0 2.2e-93 312.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ48299.1 - 1.5e-18 67.2 0.0 3.7e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HALZ PF02183.18 KXZ48299.1 - 0.23 11.7 5.8 0.49 10.6 3.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 KXZ48299.1 - 1.1 9.5 8.9 1.3 9.2 1.9 3.7 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 KXZ48299.1 - 5 7.3 69.6 0.056 13.7 16.3 3.9 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) LCM PF04072.14 KXZ48300.1 - 7.4e-16 58.6 0.0 8e-15 55.3 0.0 2.4 2 1 1 3 3 3 1 Leucine carboxyl methyltransferase zf-MYND PF01753.18 KXZ48301.1 - 1.1e-06 28.6 10.0 3.3e-06 27.1 10.0 1.9 1 0 0 1 1 1 1 MYND finger Sgf11 PF08209.11 KXZ48301.1 - 0.0082 15.7 0.6 0.028 14.0 0.6 1.9 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) LCM PF04072.14 KXZ48302.1 - 4.4e-15 56.1 0.0 8.8e-15 55.1 0.0 1.4 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Methyltransf_19 PF04672.12 KXZ48302.1 - 0.00044 19.8 0.0 0.00053 19.6 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl methyltransferase Glyoxalase_4 PF13669.6 KXZ48302.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ank_2 PF12796.7 KXZ48303.1 - 5.8e-57 190.2 13.5 2.6e-12 47.2 0.5 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ48303.1 - 6.9e-48 159.1 40.5 3.7e-06 27.1 0.4 9.7 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 KXZ48303.1 - 3.3e-47 153.0 16.8 2e-05 24.6 0.0 9.8 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 KXZ48303.1 - 1.1e-45 153.0 36.3 5.2e-09 36.2 1.7 9.8 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ48303.1 - 1e-44 150.3 19.4 9.1e-11 42.1 0.2 5.8 3 1 3 6 6 6 6 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KXZ48303.1 - 1.6 8.7 0.0 1.6 8.7 0.0 4.4 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain zf-C2H2_10 PF16588.5 KXZ48303.1 - 3.3 7.5 7.7 0.65 9.8 0.6 3.0 3 0 0 3 3 3 0 C2H2 zinc-finger Aminotran_3 PF00202.21 KXZ48305.1 - 8e-113 377.2 0.0 9.6e-113 376.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III zf-MYND PF01753.18 KXZ48306.1 - 1.6e-06 28.1 9.9 1.6e-06 28.1 9.9 2.0 2 0 0 2 2 2 1 MYND finger Ank_2 PF12796.7 KXZ48307.1 - 3.1e-07 30.9 0.0 1.8e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ48307.1 - 4.2e-06 26.9 0.0 5.8e-05 23.3 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ48307.1 - 3e-05 24.5 0.0 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48307.1 - 3.8e-05 23.8 0.2 0.065 13.8 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat zf-MYND PF01753.18 KXZ48308.1 - 6.1e-07 29.4 11.1 6.1e-07 29.4 11.1 2.2 3 0 0 3 3 3 1 MYND finger zf-MYND PF01753.18 KXZ48309.1 - 4e-07 30.0 9.9 1.4e-06 28.3 9.9 2.0 1 0 0 1 1 1 1 MYND finger SEN1_N PF12726.7 KXZ48309.1 - 0.2 9.9 0.0 4.6 5.3 0.0 2.1 2 0 0 2 2 2 0 SEN1 N terminal zf-MYND PF01753.18 KXZ48311.1 - 1.6e-06 28.1 10.0 1.6e-06 28.1 10.0 1.8 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KXZ48313.1 - 1.3e-06 28.3 9.1 3.4e-06 27.0 9.1 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ48314.1 - 7.1e-08 32.4 9.0 7.1e-08 32.4 9.0 1.7 2 0 0 2 2 2 1 MYND finger AmiS_UreI PF02293.15 KXZ48315.1 - 0.078 13.0 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 AmiS/UreI family transporter DLH PF01738.18 KXZ48316.1 - 5.1e-35 121.0 0.0 7.6e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KXZ48316.1 - 0.00061 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXZ48316.1 - 0.011 16.3 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ48316.1 - 0.031 13.9 0.2 0.089 12.4 0.2 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXZ48316.1 - 0.18 11.7 0.2 7.4 6.4 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold Tryp_inh PF17983.1 KXZ48316.1 - 9.1 6.5 10.9 0.2 11.8 3.7 2.1 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 Kazal_1 PF00050.21 KXZ48317.1 - 9.6e-59 195.2 89.3 1.7e-08 34.3 4.6 8.9 3 3 5 8 8 8 8 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KXZ48317.1 - 5.9e-46 154.4 104.7 3.5e-07 30.2 4.3 8.5 8 0 0 8 8 8 8 Kazal-type serine protease inhibitor domain Acyl-CoA_dh_M PF02770.19 KXZ48318.1 - 1.8e-17 63.3 0.0 3.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 KXZ48318.1 - 3.7e-05 23.4 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 KXZ48318.1 - 0.05 13.8 0.7 0.087 13.0 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Spc7 PF08317.11 KXZ48320.1 - 0.00012 21.1 108.6 0.016 14.1 36.1 4.7 1 1 4 5 5 5 4 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KXZ48320.1 - 0.001 19.1 39.5 0.61 10.1 0.5 7.3 2 2 4 6 6 6 5 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 KXZ48320.1 - 0.011 16.0 5.8 0.011 16.0 5.8 9.6 5 2 6 12 12 12 0 Haemolysin XhlA Syntaxin_2 PF14523.6 KXZ48320.1 - 0.015 15.7 4.4 0.015 15.7 4.4 6.6 3 2 3 6 6 6 0 Syntaxin-like protein DUF3800 PF12686.7 KXZ48320.1 - 0.03 15.0 0.2 2.2 8.9 0.2 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) RmuC PF02646.16 KXZ48320.1 - 0.042 13.0 68.6 0.12 11.5 5.5 7.7 5 2 2 7 7 7 0 RmuC family NPV_P10 PF05531.12 KXZ48320.1 - 0.078 13.5 66.5 0.31 11.5 0.8 8.9 3 1 7 10 10 10 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 KXZ48320.1 - 0.53 10.3 69.5 0.24 11.4 7.9 6.7 2 2 6 8 8 8 0 Laminin Domain II BLOC1_2 PF10046.9 KXZ48320.1 - 0.78 10.1 75.5 0.23 11.8 11.5 7.7 3 2 5 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apolipoprotein PF01442.18 KXZ48320.1 - 0.84 9.5 123.1 0.24 11.3 38.9 5.2 1 1 3 4 4 2 0 Apolipoprotein A1/A4/E domain Fmp27_WPPW PF10359.9 KXZ48320.1 - 0.91 8.3 65.7 0.11 11.3 15.6 4.6 1 1 3 4 4 4 0 RNA pol II promoter Fmp27 protein domain DUF16 PF01519.16 KXZ48320.1 - 2.4 8.7 78.1 0.15 12.6 8.9 6.7 3 1 5 8 8 8 0 Protein of unknown function DUF16 DUF948 PF06103.11 KXZ48320.1 - 6.4 7.1 50.2 0.58 10.4 1.9 8.3 3 3 5 8 8 8 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 KXZ48320.1 - 7.6 5.8 96.3 0.31 10.4 10.3 4.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) Sugarporin_N PF11471.8 KXZ48321.1 - 0.0011 18.9 12.9 0.0011 18.9 12.9 2.1 2 1 1 3 3 3 1 Maltoporin periplasmic N-terminal extension DUF3584 PF12128.8 KXZ48321.1 - 0.0038 14.8 0.4 0.0038 14.8 0.4 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Tropomyosin PF00261.20 KXZ48321.1 - 0.054 12.8 6.0 0.4 10.0 6.1 1.9 1 1 0 1 1 1 0 Tropomyosin AAA_13 PF13166.6 KXZ48321.1 - 0.3 9.7 0.6 0.41 9.2 0.6 1.1 1 0 0 1 1 1 0 AAA domain ADIP PF11559.8 KXZ48321.1 - 9.6 6.3 8.6 0.24 11.5 1.7 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NUDIX-like PF09296.11 KXZ48323.1 - 0.32 11.7 3.5 0.42 11.3 2.0 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase-like rudimentary NUDIX domain PBP_like PF12727.7 KXZ48324.1 - 0.087 11.9 1.1 0.15 11.2 1.1 1.4 1 0 0 1 1 1 0 PBP superfamily domain DUF3168 PF11367.8 KXZ48325.1 - 0.0014 18.8 0.1 0.0023 18.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3168) Pkinase PF00069.25 KXZ48326.1 - 2.7e-40 138.4 0.0 4.5e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48326.1 - 1.2e-39 136.2 0.0 9e-39 133.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ48326.1 - 5.7e-05 22.6 0.0 8.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ48326.1 - 0.00012 22.2 0.4 0.00032 20.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ48326.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXZ48326.1 - 0.042 12.8 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_9 PF00759.19 KXZ48327.1 - 3.1e-91 306.8 3.8 3.8e-91 306.5 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 BTB PF00651.31 KXZ48329.1 - 4.1e-08 33.4 0.0 8.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain NHL PF01436.21 KXZ48329.1 - 0.07 13.2 0.3 2.8 8.2 0.0 3.1 3 0 0 3 3 3 0 NHL repeat TPR_2 PF07719.17 KXZ48330.1 - 8.8e-19 66.0 8.3 1.1e-06 28.2 0.5 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ48330.1 - 1.5e-18 65.7 3.2 2.5e-07 30.2 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ48330.1 - 4.6e-12 45.1 2.5 9.9e-05 22.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ48330.1 - 1.5e-09 37.3 1.9 0.0003 20.4 0.0 3.5 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 KXZ48330.1 - 1.2e-07 31.9 10.6 0.0017 19.0 0.8 4.2 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ48330.1 - 2.4e-06 27.6 2.3 0.0047 17.0 4.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ48330.1 - 4.2e-06 27.3 14.5 0.00032 21.3 0.5 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ48330.1 - 0.00024 21.3 3.2 1.2 9.5 0.7 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ48330.1 - 0.00063 19.9 0.3 0.49 10.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ48330.1 - 0.0015 18.6 0.9 0.16 12.1 0.1 3.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KXZ48330.1 - 0.022 15.3 5.6 2.2 8.8 0.2 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ48330.1 - 0.088 12.9 0.4 11 6.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ48330.1 - 0.6 10.1 13.9 1.4 8.9 1.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ48330.1 - 0.72 10.6 5.8 27 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat GRP PF07172.11 KXZ48330.1 - 2.5 8.8 16.2 0.41 11.4 0.9 2.6 2 0 0 2 2 2 0 Glycine rich protein family Carot_N PF09150.10 KXZ48331.1 - 0.46 10.3 3.7 14 5.5 0.0 2.8 3 0 0 3 3 3 0 Orange carotenoid protein, N-terminal SAP PF02037.27 KXZ48333.1 - 0.0091 15.7 0.9 0.015 15.0 0.9 1.3 1 0 0 1 1 1 1 SAP domain JUPITER PF17054.5 KXZ48333.1 - 0.017 14.6 0.2 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 Microtubule-Associated protein Jupiter Pkinase PF00069.25 KXZ48334.1 - 2e-43 148.7 0.0 2.1e-40 138.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48334.1 - 2.6e-43 148.2 0.0 1.2e-40 139.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ48334.1 - 0.0013 18.7 1.3 0.0018 18.3 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ48334.1 - 0.0047 15.8 0.0 0.0065 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Amidohydro_1 PF01979.20 KXZ48335.1 - 4.2e-25 88.8 0.4 5.3e-25 88.5 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXZ48335.1 - 8.5e-12 45.3 7.6 4.1e-06 26.5 0.9 3.1 2 1 1 3 3 3 3 Amidohydrolase family Glyco_hydro_9 PF00759.19 KXZ48337.1 - 2.5e-07 30.5 0.6 6e-07 29.2 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 PAS_9 PF13426.7 KXZ48338.1 - 1.5e-14 54.1 0.0 4.2e-06 27.0 0.0 4.2 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 KXZ48338.1 - 9.3e-11 41.7 0.0 0.0038 17.2 0.0 4.9 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.10 KXZ48338.1 - 4.4e-09 36.6 1.3 0.00054 20.2 0.0 6.0 6 0 0 6 6 6 1 PAS fold PAS_8 PF13188.7 KXZ48338.1 - 3.9e-05 23.6 0.0 0.017 15.1 0.0 2.8 2 0 0 2 2 2 2 PAS domain MitMem_reg PF13012.6 KXZ48339.1 - 8.7e-34 116.3 0.8 3.2e-33 114.5 1.0 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXZ48339.1 - 1.6e-33 115.2 2.7 3.8e-33 113.9 0.0 2.6 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1682 PF07946.14 KXZ48339.1 - 0.014 14.7 6.2 0.021 14.1 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Coilin_N PF15862.5 KXZ48339.1 - 0.053 13.3 6.2 0.086 12.6 6.2 1.3 1 0 0 1 1 1 0 Coilin N-terminus ATP-synt_B PF00430.18 KXZ48339.1 - 0.16 12.1 10.6 0.27 11.3 10.6 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MCU PF04678.13 KXZ48339.1 - 0.2 11.7 1.7 0.32 11.1 1.7 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter SHR3_chaperone PF08229.11 KXZ48339.1 - 0.52 9.3 2.6 0.91 8.5 2.6 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 Connexin PF00029.19 KXZ48339.1 - 0.69 9.6 5.5 1 9.1 5.5 1.2 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 KXZ48339.1 - 1.7 8.7 5.1 3.1 7.9 5.1 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein SnoaL_4 PF13577.6 KXZ48340.1 - 0.038 14.1 0.2 3.4 7.8 0.1 2.8 3 0 0 3 3 3 0 SnoaL-like domain PP2C PF00481.21 KXZ48341.1 - 1.8e-20 73.7 0.0 2.1e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXZ48341.1 - 8.6e-05 22.5 0.1 0.0001 22.3 0.1 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXZ48341.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C DUF3349 PF11829.8 KXZ48341.1 - 0.12 13.2 0.1 0.17 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Kinesin PF00225.23 KXZ48343.1 - 5.2e-100 334.6 0.0 6.4e-100 334.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ48343.1 - 6.2e-23 81.4 0.0 1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding ZapB PF06005.12 KXZ48343.1 - 0.07 13.6 7.2 1.4 9.4 1.5 2.3 2 0 0 2 2 2 0 Cell division protein ZapB NRBF2 PF08961.10 KXZ48343.1 - 0.14 11.8 3.1 2.2 7.9 0.3 2.2 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 KXZ48343.1 - 0.32 11.1 4.1 4.1 7.6 0.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor Shugoshin_N PF07558.11 KXZ48343.1 - 0.4 10.6 4.4 0.26 11.2 1.5 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PLDc_N PF13396.6 KXZ48343.1 - 0.44 10.5 1.5 0.93 9.5 1.5 1.5 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DivIC PF04977.15 KXZ48343.1 - 0.47 10.3 4.2 0.89 9.4 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.18 KXZ48343.1 - 1.1 9.6 3.8 1.8 9.0 0.4 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 KXZ48343.1 - 3.8 7.7 8.6 14 5.9 4.1 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 IFT57 PF10498.9 KXZ48344.1 - 0.88 8.5 14.3 0.02 13.9 7.6 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Atg14 PF10186.9 KXZ48344.1 - 8.2 5.4 35.9 0.034 13.3 24.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2040 PF09745.9 KXZ48345.1 - 1.1e-34 119.1 20.9 1.1e-34 119.1 20.9 2.7 4 0 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Med26 PF08711.11 KXZ48346.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain BTB PF00651.31 KXZ48347.1 - 0.00011 22.4 0.0 0.00032 20.9 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain TFIIA PF03153.13 KXZ48347.1 - 0.14 12.1 1.4 0.17 11.9 1.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ASCH PF04266.14 KXZ48348.1 - 0.007 16.9 0.0 0.01 16.4 0.0 1.3 1 1 0 1 1 1 1 ASCH domain DUF4485 PF14846.6 KXZ48350.1 - 6e-21 74.3 0.7 9.7e-21 73.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) DUF3486 PF11985.8 KXZ48350.1 - 0.29 11.5 11.1 0.88 10.0 11.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Ion_trans PF00520.31 KXZ48351.1 - 3.3e-16 59.3 1.1 4.5e-16 58.8 1.1 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KXZ48351.1 - 4.1e-13 49.2 0.1 8.3e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain dCMP_cyt_deam_1 PF00383.23 KXZ48352.1 - 6.3e-25 87.0 0.0 1.1e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXZ48352.1 - 3.7e-11 42.9 0.0 6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXZ48352.1 - 0.01 15.9 4.9 0.15 12.1 0.2 3.2 2 0 0 2 2 2 0 Bd3614-like deaminase Neur_chan_LBD PF02931.23 KXZ48354.1 - 0.00046 19.7 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KXZ48354.1 - 0.00054 20.1 8.2 0.00074 19.7 8.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Myb_DNA-bind_6 PF13921.6 KXZ48355.1 - 0.0013 19.0 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXZ48355.1 - 0.0047 17.1 0.0 0.0092 16.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Isochorismatase PF00857.20 KXZ48356.1 - 8.6e-39 133.5 0.0 9.7e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1751 PF08551.10 KXZ48357.1 - 2.6e-15 56.8 2.6 2.6e-15 56.8 2.6 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXZ48357.1 - 0.038 14.0 7.1 0.064 13.2 7.1 1.4 1 0 0 1 1 1 0 Rhomboid family Ion_trans PF00520.31 KXZ48358.1 - 3.9e-17 62.3 16.0 5.2e-17 61.9 16.0 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KXZ48358.1 - 2.5e-12 46.7 0.1 7.5e-12 45.2 0.1 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain TRP PF06011.12 KXZ48361.1 - 8.4e-12 44.5 13.7 1.4e-11 43.8 13.7 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Kelch_3 PF13415.6 KXZ48361.1 - 4.8e-07 29.9 6.8 6.4e-07 29.5 0.2 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 KXZ48361.1 - 9.6e-06 25.5 3.0 6e-05 23.0 0.6 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ48361.1 - 0.0019 18.2 0.9 0.57 10.2 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 KXZ48361.1 - 0.02 15.1 0.3 0.12 12.8 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 KXZ48361.1 - 0.038 13.6 0.0 0.13 11.9 0.0 2.0 1 0 0 1 1 1 0 Kelch motif Laminin_EGF PF00053.24 KXZ48361.1 - 1.1 9.4 10.1 1.5 9.0 5.3 2.6 2 0 0 2 2 2 0 Laminin EGF domain DUF1690 PF07956.11 KXZ48362.1 - 0.072 13.5 1.6 0.11 13.0 1.6 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF1664 PF07889.12 KXZ48362.1 - 0.17 12.0 1.8 0.27 11.3 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Ank_4 PF13637.6 KXZ48363.1 - 6.2e-13 49.0 0.9 0.058 14.0 0.0 6.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48363.1 - 4.4e-11 43.2 0.0 0.00013 22.4 0.0 4.5 2 2 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48363.1 - 1.9e-10 40.1 0.1 1.9 9.3 0.0 7.0 5 1 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXZ48363.1 - 6.1e-05 23.2 0.0 0.35 11.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) F-box PF00646.33 KXZ48363.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 F-box domain Ank_2 PF12796.7 KXZ48364.1 - 2.3e-08 34.5 0.0 1.2e-05 25.8 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48364.1 - 4.3e-08 33.5 1.8 0.058 14.0 0.0 4.9 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48364.1 - 2.5e-06 27.4 0.2 6.4 7.7 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXZ48365.1 - 7e-16 58.4 0.3 0.00017 22.0 0.0 6.6 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48365.1 - 5.7e-14 52.5 0.0 0.00034 21.1 0.0 4.8 2 2 4 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48365.1 - 5.8e-10 38.5 0.1 1.9 9.3 0.0 6.9 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KXZ48365.1 - 3.8e-07 30.3 0.2 0.52 10.7 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) F-box PF00646.33 KXZ48365.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain Ank PF00023.30 KXZ48365.1 - 0.12 12.9 0.2 1.4e+02 3.2 0.0 4.7 6 0 0 6 6 6 0 Ankyrin repeat Defensin_4 PF07936.12 KXZ48365.1 - 4.8 7.1 7.4 14 5.6 0.1 3.5 3 0 0 3 3 3 0 Potassium-channel blocking toxin Ank_4 PF13637.6 KXZ48366.1 - 3e-09 37.2 0.1 0.18 12.4 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48366.1 - 2.2e-07 31.4 0.0 0.0052 17.3 0.0 2.8 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48366.1 - 2.5e-06 27.4 0.1 3.1 8.7 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXZ48367.1 - 1.4e-14 54.2 4.4 0.0029 18.1 0.0 7.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48367.1 - 2.4e-13 50.4 0.0 0.00076 20.0 0.0 4.8 2 2 4 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48367.1 - 1.2e-09 37.6 0.3 1.9 9.3 0.0 7.0 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KXZ48367.1 - 2e-06 28.0 0.4 0.5 10.8 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) F-box PF00646.33 KXZ48367.1 - 0.015 15.2 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain Ank PF00023.30 KXZ48367.1 - 0.059 13.8 0.4 1.4e+02 3.2 0.0 4.9 6 0 0 6 6 6 0 Ankyrin repeat Defensin_4 PF07936.12 KXZ48367.1 - 5.3 7.0 7.5 14 5.6 0.1 3.5 3 0 0 3 3 3 0 Potassium-channel blocking toxin Ion_trans PF00520.31 KXZ48368.1 - 2.5e-22 79.3 0.1 3.2e-22 79.0 0.1 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KXZ48369.1 - 3.2e-50 170.6 8.8 4.6e-50 170.1 8.8 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXZ48369.1 - 0.0027 16.5 17.8 0.12 11.0 2.2 3.1 2 1 1 3 3 3 3 Polycystin cation channel NB-LRR PF12061.8 KXZ48369.1 - 0.21 10.9 0.8 0.32 10.3 0.8 1.2 1 0 0 1 1 1 0 Late blight resistance protein R1 FAM176 PF14851.6 KXZ48369.1 - 0.27 10.9 9.2 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 FAM176 family Nop14 PF04147.12 KXZ48369.1 - 2.1 6.4 5.0 2.7 6.1 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.6 KXZ48369.1 - 4.5 6.8 7.7 9.9 5.7 7.7 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain CENP-B_dimeris PF09026.10 KXZ48369.1 - 6.8 7.2 14.2 14 6.1 14.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ion_trans PF00520.31 KXZ48370.1 - 2.4e-58 197.3 15.1 1.8e-36 125.6 8.0 2.1 2 0 0 2 2 2 2 Ion transport protein GPHH PF16905.5 KXZ48370.1 - 2.3e-08 33.7 0.0 4.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KXZ48370.1 - 8.1e-08 31.4 15.9 6.8e-05 21.7 0.4 4.1 3 1 1 4 4 4 4 Polycystin cation channel TPT PF03151.16 KXZ48371.1 - 5.4e-14 52.2 16.7 6.2e-14 52.0 16.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Phage_holin_2_4 PF16082.5 KXZ48371.1 - 0.026 14.2 1.3 0.026 14.2 1.3 2.9 2 1 1 3 3 3 0 Bacteriophage holin family, superfamily II-like EamA PF00892.20 KXZ48371.1 - 0.028 14.6 23.2 0.5 10.5 9.0 2.2 2 0 0 2 2 2 0 EamA-like transporter family DUF4946 PF16304.5 KXZ48371.1 - 3.1 7.5 5.1 0.25 11.0 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4946) DUF5320 PF17253.2 KXZ48374.1 - 0.1 13.7 0.1 0.1 13.7 0.1 11.3 9 3 2 12 12 12 0 Family of unknown function (DUF5320) MORN PF02493.20 KXZ48375.1 - 1.7e-34 115.6 51.8 1.1e-07 31.3 1.2 8.8 9 0 0 9 9 9 8 MORN repeat CH PF00307.31 KXZ48375.1 - 1.2e-05 25.4 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF3048_C PF17479.2 KXZ48375.1 - 0.36 11.2 11.1 1.4 9.3 1.0 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain BcrAD_BadFG PF01869.20 KXZ48376.1 - 5.8e-14 52.2 0.0 7.3e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DUF1990 PF09348.10 KXZ48377.1 - 2.2e-31 109.0 0.2 2.7e-31 108.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) LRR_4 PF12799.7 KXZ48378.1 - 3.2e-19 68.7 8.9 1.5e-05 25.3 0.8 4.9 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ48378.1 - 9e-15 54.2 15.3 1.4e-08 34.4 2.9 4.0 3 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KXZ48378.1 - 1.1e-12 47.8 0.5 5.1e-05 22.9 0.1 3.1 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KXZ48378.1 - 7.7e-09 34.9 7.1 5 7.4 0.2 7.4 6 1 1 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 KXZ48378.1 - 0.00082 19.6 12.4 8.9 7.3 0.5 6.6 6 2 0 6 6 6 1 Leucine Rich Repeat Transglut_core PF01841.19 KXZ48378.1 - 0.011 16.2 0.3 0.021 15.2 0.3 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily EF-hand_6 PF13405.6 KXZ48378.1 - 0.026 14.5 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KXZ48378.1 - 0.037 14.5 0.1 0.078 13.4 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair Ribosomal_S7 PF00177.21 KXZ48379.1 - 3e-21 75.6 1.2 3.9e-21 75.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Pkinase PF00069.25 KXZ48380.1 - 9.5e-63 212.0 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48380.1 - 3.4e-19 69.2 0.0 4.7e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ48380.1 - 5.3e-09 36.4 0.1 5.8e-06 26.4 0.2 2.8 2 1 2 4 4 4 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ48380.1 - 0.031 13.0 0.0 0.065 12.0 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF2459 PF09601.10 KXZ48380.1 - 0.038 13.8 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Kdo PF06293.14 KXZ48380.1 - 0.045 13.1 0.1 0.074 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXZ48380.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ish1 PF10281.9 KXZ48380.1 - 0.18 12.1 1.2 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein FAD_binding_2 PF00890.24 KXZ48381.1 - 2e-124 415.8 3.6 2.8e-124 415.4 3.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXZ48381.1 - 5.3e-45 152.5 0.5 8.2e-45 151.9 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KXZ48381.1 - 0.00012 21.5 0.7 0.12 11.6 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KXZ48381.1 - 0.00058 19.0 1.1 0.026 13.6 1.8 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXZ48381.1 - 0.0011 18.3 0.6 0.0029 16.9 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXZ48381.1 - 0.0041 16.4 0.3 0.0073 15.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXZ48381.1 - 0.051 13.2 0.7 0.15 11.6 0.7 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXZ48381.1 - 0.44 9.2 2.5 0.66 8.6 0.5 2.2 3 0 0 3 3 3 0 HI0933-like protein CLP_protease PF00574.23 KXZ48382.1 - 1e-24 87.4 0.0 1.2e-23 83.9 0.0 2.3 2 1 0 2 2 2 1 Clp protease Plectin PF00681.20 KXZ48382.1 - 0.17 11.8 0.2 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Plectin repeat E1-E2_ATPase PF00122.20 KXZ48383.1 - 4.6e-31 107.7 0.5 4.6e-31 107.7 0.5 2.5 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXZ48383.1 - 1.6e-23 84.1 5.2 5.1e-22 79.2 5.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXZ48383.1 - 0.022 14.5 1.0 0.045 13.5 1.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 KXZ48384.1 - 2.2e-65 220.7 0.7 2.2e-65 220.7 0.7 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ48384.1 - 7.1e-19 68.2 0.0 2.1e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 KXZ48384.1 - 2.7e-06 27.6 10.1 2.7e-06 27.6 10.1 6.1 5 1 1 6 6 6 1 HSA DEAD PF00270.29 KXZ48384.1 - 2.9e-05 23.9 0.0 0.00027 20.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase BACK PF07707.15 KXZ48385.1 - 9.4e-08 32.1 0.1 1.7e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ48385.1 - 3.4e-06 27.3 0.0 5.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Serglycin PF04360.12 KXZ48385.1 - 5.3 7.0 13.9 0.21 11.5 4.0 2.4 2 0 0 2 2 2 0 Serglycin DUF4126 PF13548.6 KXZ48386.1 - 4.7e-05 23.2 1.7 0.31 10.7 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4126) DUF3242 PF11586.8 KXZ48386.1 - 0.12 12.2 0.8 16 5.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) DUF2730 PF10805.8 KXZ48386.1 - 0.53 10.4 5.5 9.6 6.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Ank_2 PF12796.7 KXZ48387.1 - 3.9e-13 49.8 0.1 4.9e-06 27.0 0.0 4.0 3 2 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48387.1 - 1.7e-08 34.8 3.9 0.006 17.1 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48387.1 - 0.00014 22.0 2.7 96 4.1 0.0 7.3 9 0 0 9 9 9 0 Ankyrin repeat Ank_5 PF13857.6 KXZ48387.1 - 0.0028 17.9 1.7 0.13 12.6 0.2 4.0 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48387.1 - 1 9.9 4.4 2.2e+02 2.6 0.0 5.2 6 0 0 6 6 6 0 Ankyrin repeat Peptidase_M11 PF05548.11 KXZ48389.1 - 4.6e-32 111.4 0.6 2e-31 109.3 0.6 1.9 1 1 0 1 1 1 1 Gametolysin peptidase M11 Chloroa_b-bind PF00504.21 KXZ48390.1 - 4.6e-51 173.5 0.0 6.6e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF676 PF05057.14 KXZ48391.1 - 2.7e-20 72.8 0.0 3.5e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXZ48391.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.4 1 1 1 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KXZ48391.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 KXZ48391.1 - 0.036 13.6 0.0 0.087 12.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.12 KXZ48391.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase LRR_8 PF13855.6 KXZ48392.1 - 1.4e-12 47.2 7.4 0.006 16.3 0.0 6.7 5 1 2 7 7 7 3 Leucine rich repeat LRR_4 PF12799.7 KXZ48392.1 - 1.3e-11 44.5 8.7 0.0022 18.4 0.3 5.7 3 3 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ48392.1 - 6e-09 35.2 8.9 0.031 14.8 0.6 8.6 8 1 2 10 10 10 1 Leucine Rich Repeat LRR_6 PF13516.6 KXZ48392.1 - 7e-06 25.7 5.7 0.73 10.0 0.1 6.9 8 0 0 8 8 8 2 Leucine Rich repeat Cpn60_TCP1 PF00118.24 KXZ48393.1 - 2.2e-14 53.0 0.4 2.6e-09 36.2 0.0 3.7 4 1 0 4 4 4 3 TCP-1/cpn60 chaperonin family Peptidase_M41 PF01434.18 KXZ48394.1 - 8.2e-66 221.5 0.0 1.4e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXZ48394.1 - 7.5e-45 152.6 0.0 1.6e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ48394.1 - 3.7e-10 39.4 0.0 8.8e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KXZ48394.1 - 0.00014 22.1 0.0 0.00057 20.2 0.0 1.9 2 0 0 2 2 2 1 FtsH Extracellular TIP49 PF06068.13 KXZ48394.1 - 0.00015 21.1 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KXZ48394.1 - 0.00017 21.6 0.3 0.0013 18.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KXZ48394.1 - 0.00049 20.5 1.0 0.0063 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ48394.1 - 0.00086 19.7 0.8 0.018 15.4 0.1 2.9 2 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KXZ48394.1 - 0.00087 19.1 0.0 0.002 17.9 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KXZ48394.1 - 0.0009 19.0 0.0 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ48394.1 - 0.0034 17.6 0.1 0.099 12.9 0.1 2.8 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXZ48394.1 - 0.0095 15.3 0.2 0.03 13.7 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXZ48394.1 - 0.014 15.6 0.0 0.053 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXZ48394.1 - 0.026 15.1 0.0 0.077 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXZ48394.1 - 0.042 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ48394.1 - 0.058 13.0 1.2 0.88 9.1 0.4 2.6 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 KXZ48394.1 - 0.062 13.4 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 KXZ48394.1 - 0.29 11.7 1.1 0.61 10.6 0.2 1.9 2 0 0 2 2 1 0 ABC transporter Ephrin_rec_like PF07699.13 KXZ48395.1 - 0.00045 19.9 18.5 0.00083 19.1 7.2 2.7 1 1 2 3 3 3 3 Putative ephrin-receptor like DUF563 PF04577.14 KXZ48395.1 - 0.00093 19.4 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF4298 PF14131.6 KXZ48395.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) NCD3G PF07562.14 KXZ48395.1 - 0.072 13.1 9.3 1.1 9.3 0.8 2.7 1 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KXZ48395.1 - 3.4 8.1 10.6 7.9 7.0 0.6 3.1 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region DUF563 PF04577.14 KXZ48396.1 - 2e-29 103.2 0.0 4.1e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ephrin_rec_like PF07699.13 KXZ48396.1 - 0.00092 18.9 18.9 0.0046 16.7 6.1 2.6 1 1 1 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 KXZ48396.1 - 0.49 10.4 11.5 1.2 9.2 2.3 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KXZ48396.1 - 1 9.8 8.9 1.2 9.5 1.2 2.9 2 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region Retrotran_gag_2 PF14223.6 KXZ48397.1 - 3e-16 59.3 0.0 6.3e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KXZ48397.1 - 1e-10 41.9 0.0 3.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KXZ48397.1 - 2.1e-08 33.9 0.0 4.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 KXZ48397.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4219 PF13961.6 KXZ48397.1 - 0.1 12.3 0.5 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) DUF3813 PF12758.7 KXZ48397.1 - 0.47 10.8 2.8 2 8.8 2.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) FSH1 PF03959.13 KXZ48398.1 - 3.3e-22 79.2 0.0 1.1e-20 74.2 0.0 2.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) UPF0176_N PF17773.1 KXZ48398.1 - 5.5e-14 52.3 0.0 1.8e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 KXZ48398.1 - 0.033 14.7 0.0 0.093 13.3 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain Sgf11 PF08209.11 KXZ48399.1 - 1.7e-16 59.5 0.4 2.9e-16 58.7 0.4 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KXZ48399.1 - 0.018 14.9 0.7 0.031 14.2 0.7 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DNA_RNApol_7kD PF03604.13 KXZ48399.1 - 0.1 12.3 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_7 PF02591.15 KXZ48399.1 - 0.11 12.7 0.2 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain ubiquitin PF00240.23 KXZ48401.1 - 7.6e-10 38.4 0.0 9.4e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family PPDK_N PF01326.19 KXZ48402.1 - 9.1e-29 100.8 0.0 1.3e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.19 KXZ48402.1 - 2.7e-05 24.0 0.0 6.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain DnaJ PF00226.31 KXZ48403.1 - 1.4e-20 73.1 0.2 2.2e-20 72.5 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain SET PF00856.28 KXZ48405.1 - 6.9e-05 23.3 0.0 0.00013 22.4 0.0 1.5 1 1 0 1 1 1 1 SET domain DUF2020 PF09449.10 KXZ48405.1 - 3.7 7.4 8.5 0.49 10.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) Pkinase PF00069.25 KXZ48406.1 - 3.8e-63 213.3 0.0 4.7e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48406.1 - 6.5e-36 123.9 0.0 8.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ48406.1 - 1.8e-07 30.3 0.0 2.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ48406.1 - 2.8e-06 26.9 0.1 2.6e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KXZ48406.1 - 0.023 14.3 0.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXZ48406.1 - 0.054 13.1 0.1 4 7.0 0.0 2.1 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 KXZ48406.1 - 0.098 12.6 2.7 0.18 11.7 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ48407.1 - 8.5e-15 54.8 0.0 1.2e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48407.1 - 1.7e-12 47.2 0.0 3.6e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase YmgD PF16456.5 KXZ48408.1 - 0.00081 19.4 0.0 4.3 7.5 0.0 3.4 3 0 0 3 3 3 2 YmgD protein DUF2807 PF10988.8 KXZ48408.1 - 0.18 11.5 1.6 1.7 8.4 0.0 2.6 2 1 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Pkinase PF00069.25 KXZ48409.1 - 2e-27 96.2 0.0 1.4e-12 47.5 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48409.1 - 4.7e-24 85.1 0.0 9.1e-11 41.5 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ48409.1 - 0.0098 14.7 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Ank_2 PF12796.7 KXZ48411.1 - 2.1e-12 47.4 0.0 0.0014 19.2 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48411.1 - 6.6e-12 45.7 2.6 0.00082 19.9 0.0 6.1 5 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48411.1 - 5.8e-07 29.3 3.0 40 5.3 0.1 8.2 9 0 0 9 9 9 0 Ankyrin repeat Ank_5 PF13857.6 KXZ48411.1 - 0.00025 21.3 5.1 9 6.8 0.0 5.7 4 1 2 6 6 6 2 Ankyrin repeats (many copies) F-box PF00646.33 KXZ48411.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXZ48413.1 - 4.3e-06 26.5 0.4 8.5e-06 25.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ48413.1 - 3.6e-05 23.5 0.4 6.4e-05 22.7 0.4 1.4 1 0 0 1 1 1 1 F-box domain SRPRB PF09439.10 KXZ48414.1 - 8.3e-29 100.3 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KXZ48414.1 - 3.6e-15 55.9 0.0 6.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXZ48414.1 - 3.3e-09 36.8 0.0 5.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KXZ48414.1 - 2e-08 34.5 0.0 3.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KXZ48414.1 - 1.2e-07 31.4 0.0 3.1e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 KXZ48414.1 - 9e-07 28.6 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 KXZ48414.1 - 0.00019 21.0 0.0 0.00038 20.0 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 KXZ48414.1 - 0.0005 20.3 0.3 0.0031 17.8 0.2 2.2 1 1 1 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KXZ48414.1 - 0.0016 17.8 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KXZ48414.1 - 0.0024 17.7 0.1 0.046 13.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA PF00004.29 KXZ48414.1 - 0.025 15.0 0.5 0.16 12.4 0.5 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIR_2 PF13676.6 KXZ48414.1 - 0.044 14.4 0.0 0.067 13.8 0.0 1.3 1 0 0 1 1 1 0 TIR domain G-alpha PF00503.20 KXZ48414.1 - 0.06 12.5 0.0 7.9 5.5 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit IstB_IS21 PF01695.17 KXZ48414.1 - 0.075 12.8 0.1 0.3 10.8 0.1 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein TniB PF05621.11 KXZ48414.1 - 0.08 12.3 0.1 0.52 9.7 0.0 2.1 2 1 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KXZ48414.1 - 0.097 12.6 0.0 7.6 6.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KXZ48414.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KXZ48414.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KXZ48414.1 - 0.17 12.2 2.0 3.4 8.0 1.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain zinc_ribbon_6 PF14599.6 KXZ48415.1 - 8.8e-26 89.7 0.1 8.8e-26 89.7 0.1 3.7 3 1 1 4 4 2 1 Zinc-ribbon zf-CHY PF05495.12 KXZ48415.1 - 9.9e-16 58.0 16.0 9.9e-16 58.0 16.0 4.0 2 1 1 3 3 2 1 CHY zinc finger zf-RING_2 PF13639.6 KXZ48415.1 - 1e-06 29.0 10.9 1e-06 29.0 10.9 5.4 3 2 2 5 5 3 1 Ring finger domain zf-RING_5 PF14634.6 KXZ48415.1 - 5e-06 26.4 9.2 5e-06 26.4 9.2 6.1 2 1 2 5 5 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXZ48415.1 - 7.3e-06 25.9 10.6 7.3e-06 25.9 10.6 3.8 4 1 0 4 4 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ48415.1 - 1.4e-05 24.8 10.9 1.4e-05 24.8 10.9 5.6 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ48415.1 - 2.1e-05 24.3 9.8 2.1e-05 24.3 9.8 5.1 3 3 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.12 KXZ48415.1 - 0.11 12.0 2.7 0.13 11.7 2.7 1.1 1 0 0 1 1 1 0 SDA1 Shadoo PF14999.6 KXZ48415.1 - 0.74 9.9 10.7 1.3 9.1 10.7 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective CDC45 PF02724.14 KXZ48415.1 - 1 7.6 3.8 1.3 7.3 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXZ48415.1 - 4 5.5 9.0 5.2 5.2 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KXZ48415.1 - 5.8 6.6 9.6 8.1 6.1 9.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 KXZ48416.1 - 6.4e-07 30.0 0.6 0.06 14.2 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ48416.1 - 0.14 12.4 0.0 2.9 8.2 0.0 2.9 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Hydrolase_4 PF12146.8 KXZ48417.1 - 2.1e-34 118.8 5.5 6.6e-17 61.6 0.0 3.5 3 0 0 3 3 3 3 Serine aminopeptidase, S33 PDEase_I PF00233.19 KXZ48417.1 - 8.6e-09 35.5 0.3 8.6e-09 35.5 0.3 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Abhydrolase_1 PF00561.20 KXZ48417.1 - 0.0085 15.8 2.6 0.14 11.7 2.6 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 KXZ48417.1 - 0.054 13.4 1.9 0.1 12.6 1.9 1.3 1 0 0 1 1 1 0 Cutinase Peptidase_M11 PF05548.11 KXZ48419.1 - 2.7e-77 260.0 0.1 3.8e-77 259.5 0.1 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Cu-binding_MopE PF11617.8 KXZ48419.1 - 0.0065 16.6 6.5 0.018 15.2 6.5 1.7 1 0 0 1 1 1 1 Putative metal-binding motif Peptidase_M66 PF10462.9 KXZ48419.1 - 0.024 13.6 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 AsmA_2 PF13502.6 KXZ48421.1 - 0.099 12.2 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 AsmA-like C-terminal region Peptidase_M11 PF05548.11 KXZ48422.1 - 7.6e-28 97.6 0.1 2.2e-27 96.1 0.1 1.7 1 1 0 1 1 1 1 Gametolysin peptidase M11 DUF21 PF01595.20 KXZ48422.1 - 1.1e-20 74.1 0.0 1.8e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Cu-binding_MopE PF11617.8 KXZ48422.1 - 0.00071 19.7 3.5 0.0016 18.6 3.5 1.6 1 0 0 1 1 1 1 Putative metal-binding motif CBS PF00571.28 KXZ48422.1 - 0.00087 19.7 2.4 0.44 11.0 0.2 3.4 3 0 0 3 3 3 2 CBS domain AAA PF00004.29 KXZ48423.1 - 7.4e-11 42.6 0.0 1.3e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MDMPI_N PF11716.8 KXZ48423.1 - 0.7 10.6 5.6 1.2 9.8 4.2 2.0 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain rRNA_processing PF08524.11 KXZ48423.1 - 3.6 7.6 7.2 6.9 6.7 7.2 1.4 1 0 0 1 1 1 0 rRNA processing Baculo_PEP_C PF04513.12 KXZ48424.1 - 0.0023 18.0 26.1 0.18 11.9 1.7 6.2 4 3 3 7 7 7 3 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KXZ48424.1 - 0.0033 17.8 18.9 4.3 7.9 2.5 6.8 6 1 1 7 7 5 2 Nucleopolyhedrovirus P10 protein EF-hand_6 PF13405.6 KXZ48424.1 - 0.026 14.4 0.0 0.089 12.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KXZ48424.1 - 0.052 14.0 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 1 0 EF-hand domain pair DUF1664 PF07889.12 KXZ48424.1 - 0.089 12.8 16.8 5.9 6.9 1.2 5.4 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) DASH_Dad1 PF08649.10 KXZ48424.1 - 0.13 12.4 0.3 2 8.6 0.2 3.0 2 0 0 2 2 2 0 DASH complex subunit Dad1 EF-hand_1 PF00036.32 KXZ48424.1 - 0.24 11.0 0.8 0.48 10.1 0.0 2.0 2 0 0 2 2 1 0 EF hand Tn7_Tnp_TnsA_C PF08721.11 KXZ48424.1 - 1.1 10.0 5.2 2.3 8.9 0.0 4.0 4 0 0 4 4 3 0 TnsA endonuclease C terminal Allexi_40kDa PF05549.11 KXZ48424.1 - 1.2 8.6 12.4 3.5 7.1 2.1 3.9 3 1 1 4 4 4 0 Allexivirus 40kDa protein Ino80_Iec3 PF14612.6 KXZ48424.1 - 1.4 9.5 8.9 0.11 13.2 2.7 2.2 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling APG17 PF04108.12 KXZ48424.1 - 1.4 7.9 21.7 21 4.1 21.6 3.4 1 1 0 1 1 1 0 Autophagy protein Apg17 Leu_zip PF15294.6 KXZ48424.1 - 1.7 8.1 24.8 0.44 10.0 5.1 3.6 3 1 0 3 3 3 0 Leucine zipper COG5 PF10392.9 KXZ48424.1 - 1.8 8.7 16.7 27 5.0 3.8 5.0 4 2 2 6 6 6 0 Golgi transport complex subunit 5 BAR_3 PF16746.5 KXZ48424.1 - 2.4 7.8 6.8 15 5.2 2.5 2.8 2 0 0 2 2 2 0 BAR domain of APPL family DUF148 PF02520.17 KXZ48424.1 - 3 8.0 13.3 5.6 7.1 0.6 4.2 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF4618 PF15397.6 KXZ48424.1 - 3.1 7.1 16.9 1.4 8.2 0.6 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) SF-assemblin PF06705.11 KXZ48424.1 - 3.9 6.7 17.5 0.029 13.7 2.6 2.9 2 1 1 3 3 3 0 SF-assemblin/beta giardin SesA PF17107.5 KXZ48424.1 - 4.5 7.5 12.7 2.4 8.4 6.4 3.6 2 2 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HAP1_N PF04849.13 KXZ48424.1 - 7.3 5.7 20.6 0.032 13.4 6.7 3.1 3 0 0 3 3 3 0 HAP1 N-terminal conserved region XhlA PF10779.9 KXZ48424.1 - 7.7 6.8 6.2 4.8 7.5 0.1 4.0 4 0 0 4 4 3 0 Haemolysin XhlA AAA_13 PF13166.6 KXZ48424.1 - 8.9 4.8 20.7 0.13 10.9 4.6 3.0 2 1 1 3 3 3 0 AAA domain Rep_fac-A_C PF08646.10 KXZ48425.1 - 1.9e-37 128.2 0.0 7.2e-37 126.4 0.0 1.8 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KXZ48425.1 - 2.1e-22 78.9 0.0 3.3e-21 75.0 0.0 2.3 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 KXZ48425.1 - 8.5e-09 35.3 0.1 3.6e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 KXZ48425.1 - 0.0025 17.8 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Ank_4 PF13637.6 KXZ48426.1 - 0.00018 22.0 2.2 17 6.1 0.0 6.3 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48426.1 - 0.12 12.9 0.0 5.6 7.6 0.0 3.3 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 KXZ48427.1 - 0.13 12.9 0.0 0.64 10.6 0.0 2.2 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Metallophos PF00149.28 KXZ48428.1 - 1.7e-08 35.2 0.0 2.6e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_1 PF01344.25 KXZ48428.1 - 0.022 14.3 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Kelch motif EF-hand_5 PF13202.6 KXZ48429.1 - 7.8e-14 50.5 2.0 2.3e-06 26.8 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 KXZ48429.1 - 3.2e-12 45.0 3.3 1.6e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KXZ48429.1 - 3.8e-11 43.3 0.2 3.8e-11 43.3 0.2 2.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ48429.1 - 2.7e-10 39.3 1.4 5.4e-05 22.8 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KXZ48429.1 - 8.9e-06 25.5 3.1 0.021 14.6 0.8 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KXZ48429.1 - 0.00066 19.9 0.0 0.0026 18.0 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KXZ48429.1 - 0.0043 17.3 0.0 0.0079 16.5 0.0 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region RE_NgoBV PF09564.10 KXZ48429.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 NgoBV restriction endonuclease DUF455 PF04305.14 KXZ48430.1 - 7.2e-38 130.5 0.0 9.1e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) HLH PF00010.26 KXZ48431.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Acyl_transf_1 PF00698.21 KXZ48432.1 - 5.3e-26 91.9 0.3 7.3e-26 91.4 0.3 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 KXZ48432.1 - 0.017 14.9 0.1 0.24 11.1 0.1 2.1 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis HAUS2 PF15003.6 KXZ48433.1 - 6e-09 35.9 0.1 7.2e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Thioredoxin PF00085.20 KXZ48435.1 - 4.2e-32 110.2 0.1 5e-32 109.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ48435.1 - 5.1e-08 33.3 0.1 1.9e-07 31.5 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ48435.1 - 1.8e-07 31.4 0.0 1.3e-05 25.5 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXZ48435.1 - 3.3e-07 30.1 0.1 4e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KXZ48435.1 - 1.6e-05 24.8 0.0 2.7e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KXZ48435.1 - 0.00043 20.4 0.0 0.00075 19.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KXZ48435.1 - 0.00081 19.1 0.1 0.0018 18.0 0.0 1.6 1 1 1 2 2 2 1 Redoxin Thioredoxin_3 PF13192.6 KXZ48435.1 - 0.0013 18.8 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 KXZ48435.1 - 0.0018 17.7 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 KXZ48435.1 - 0.0076 16.2 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 KXZ48435.1 - 0.0091 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 KXZ48435.1 - 0.015 15.0 0.2 0.51 10.0 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin KRTAP PF11759.8 KXZ48436.1 - 0.16 12.5 7.8 0.31 11.6 7.8 1.4 1 0 0 1 1 1 0 Keratin-associated matrix Ribosomal_L5e PF17144.4 KXZ48437.1 - 2.5e-80 268.2 0.0 3.9e-80 267.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KXZ48437.1 - 1.5e-30 105.9 4.9 1.5e-30 105.9 4.9 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KXZ48437.1 - 0.049 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast PDDEXK_5 PF11645.8 KXZ48437.1 - 0.17 11.8 2.2 0.41 10.6 2.2 1.6 1 1 0 1 1 1 0 PD-(D/E)XK endonuclease F-box-like PF12937.7 KXZ48438.1 - 2.3e-07 30.6 0.0 5.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like PP2 PF14299.6 KXZ48438.1 - 1.6e-05 25.0 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Phloem protein 2 F-box PF00646.33 KXZ48438.1 - 2.8e-05 23.9 1.4 0.00066 19.5 0.2 2.3 2 0 0 2 2 2 1 F-box domain Dirigent PF03018.14 KXZ48439.1 - 6.2e-07 29.3 0.1 7.6e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Dirigent-like protein Allene_ox_cyc PF06351.11 KXZ48439.1 - 8.2e-07 28.9 0.3 9.6e-07 28.7 0.3 1.1 1 0 0 1 1 1 1 Allene oxide cyclase RelA_SpoT PF04607.17 KXZ48440.1 - 1e-30 106.4 0.0 3.8e-30 104.6 0.0 1.8 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins LUC7 PF03194.15 KXZ48441.1 - 2e-39 135.8 11.1 5.1e-31 108.2 8.4 2.2 1 1 1 2 2 2 2 LUC7 N_terminus HD_4 PF13328.6 KXZ48441.1 - 3.5e-31 108.1 0.5 9e-31 106.7 0.5 1.7 1 0 0 1 1 1 1 HD domain FlgN PF05130.12 KXZ48441.1 - 0.21 12.1 7.8 0.098 13.2 3.6 2.3 2 0 0 2 2 2 0 FlgN protein DUF4164 PF13747.6 KXZ48441.1 - 3.1 8.2 9.1 2.9 8.2 6.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) T3SS_needle_F PF09392.10 KXZ48441.1 - 6.9 6.9 6.6 0.58 10.4 0.2 2.4 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Glyco_transf_49 PF13896.6 KXZ48442.1 - 1.4e-38 133.1 0.1 1.9e-37 129.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan UDPGP PF01704.18 KXZ48443.1 - 4.5e-14 51.9 0.0 6.5e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pkinase_Tyr PF07714.17 KXZ48444.1 - 1e-36 126.6 0.0 2.9e-31 108.7 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ48444.1 - 7.2e-35 120.6 0.0 1.8e-34 119.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ48444.1 - 4.7e-05 22.3 0.0 7.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KXZ48444.1 - 0.048 13.3 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M11 PF05548.11 KXZ48445.1 - 4.6e-33 114.7 0.4 4.6e-33 114.7 0.4 1.5 2 0 0 2 2 2 1 Gametolysin peptidase M11 Reprolysin_3 PF13582.6 KXZ48445.1 - 0.0012 19.3 0.1 0.003 18.1 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXZ48445.1 - 0.003 17.7 1.1 0.0066 16.6 1.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 ACP PF06857.11 KXZ48445.1 - 0.025 14.8 0.7 0.049 13.9 0.7 1.4 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Peptidase_M32 PF02074.15 KXZ48445.1 - 0.079 11.7 0.3 0.12 11.1 0.3 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Peptidase_M66 PF10462.9 KXZ48445.1 - 0.13 11.2 1.3 0.73 8.7 0.2 2.2 2 0 0 2 2 2 0 Peptidase M66 Pkinase_Tyr PF07714.17 KXZ48446.1 - 1.1e-36 126.4 0.0 6.2e-31 107.6 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ48446.1 - 1.7e-35 122.7 0.0 4.8e-35 121.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ48446.1 - 0.0001 21.3 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KXZ48446.1 - 0.071 12.7 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M17 PF00883.21 KXZ48447.1 - 4.4e-87 292.3 0.0 6.7e-87 291.7 0.0 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KXZ48447.1 - 1.9e-07 31.0 0.1 9.6e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain DUF3707 PF12499.8 KXZ48449.1 - 1.4e-60 204.0 16.0 2.5e-35 122.1 3.2 2.3 2 0 0 2 2 2 2 Pherophorin Ank_2 PF12796.7 KXZ48450.1 - 3.8e-07 30.6 0.9 0.00019 22.0 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48450.1 - 9.7e-06 26.0 1.4 0.58 10.8 0.3 4.9 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48450.1 - 0.00062 20.0 1.3 0.21 11.9 0.1 3.7 1 1 3 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48450.1 - 0.0021 18.4 2.1 42 5.2 0.0 6.2 7 0 0 7 7 7 0 Ankyrin repeat HEAT_2 PF13646.6 KXZ48450.1 - 0.017 15.5 8.8 0.088 13.2 0.3 2.5 2 0 0 2 2 2 0 HEAT repeats Ank_4 PF13637.6 KXZ48451.1 - 1.6e-05 25.4 1.3 6.2 7.5 0.0 4.6 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48451.1 - 7.4e-05 23.3 0.1 0.36 11.5 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48451.1 - 0.00011 22.4 0.0 2.2 9.1 0.0 4.9 4 1 1 5 5 5 1 Ankyrin repeat DBD_Tnp_Mut PF03108.15 KXZ48451.1 - 0.2 11.7 0.1 18 5.4 0.0 2.3 2 0 0 2 2 2 0 MuDR family transposase Roc PF08477.13 KXZ48452.1 - 2.6e-08 34.1 0.0 5.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 KXZ48452.1 - 0.0011 17.8 0.2 0.0082 15.0 0.0 2.1 2 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 KXZ48452.1 - 0.0063 16.6 0.0 0.016 15.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXZ48452.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 KXZ48452.1 - 0.16 11.8 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Robl_LC7 PF03259.17 KXZ48453.1 - 3.2e-29 100.5 0.0 3.6e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain RsmJ PF04378.13 KXZ48453.1 - 0.0048 16.2 0.0 0.0072 15.6 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ UPF0176_N PF17773.1 KXZ48453.1 - 0.039 14.3 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain LAMTOR5 PF16672.5 KXZ48453.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 Ank_3 PF13606.6 KXZ48457.1 - 7.7e-07 28.9 0.7 0.82 10.4 0.0 6.7 8 0 0 8 8 8 1 Ankyrin repeat Ank_4 PF13637.6 KXZ48457.1 - 2.3e-06 28.0 6.0 0.018 15.6 0.1 5.6 5 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48457.1 - 1.1e-05 26.0 0.1 0.055 14.1 0.0 4.1 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) ABC_tran PF00005.27 KXZ48458.1 - 1.8e-49 167.8 0.0 6.1e-29 101.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXZ48458.1 - 8.3e-37 127.3 20.8 7.5e-25 88.1 6.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXZ48458.1 - 3.2e-09 36.5 3.7 0.0064 15.9 0.1 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ48458.1 - 4.5e-06 26.3 0.2 0.075 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KXZ48458.1 - 1.9e-05 24.6 0.2 0.06 13.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXZ48458.1 - 2e-05 24.6 0.3 0.32 11.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KXZ48458.1 - 3.1e-05 24.4 2.6 0.059 13.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain DEAD PF00270.29 KXZ48458.1 - 4.3e-05 23.4 0.1 0.035 13.9 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_23 PF13476.6 KXZ48458.1 - 0.00021 21.9 0.0 0.38 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KXZ48458.1 - 0.00028 20.1 1.3 0.42 9.8 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain Dynamin_N PF00350.23 KXZ48458.1 - 0.00089 19.4 0.5 0.13 12.3 0.2 2.5 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 KXZ48458.1 - 0.00095 18.7 0.1 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KXZ48458.1 - 0.0011 18.3 0.1 0.28 10.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KXZ48458.1 - 0.0012 19.2 0.7 1.1 9.6 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXZ48458.1 - 0.0022 17.7 1.4 0.8 9.4 0.2 3.1 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXZ48458.1 - 0.0069 15.5 0.0 0.07 12.2 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KXZ48458.1 - 0.0071 16.2 0.4 3.8 7.2 0.1 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 KXZ48458.1 - 0.012 15.3 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.12 KXZ48458.1 - 0.013 15.0 1.1 0.065 12.7 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein DUF87 PF01935.17 KXZ48458.1 - 0.019 15.0 1.2 0.86 9.6 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 KXZ48458.1 - 0.02 14.8 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 KXZ48458.1 - 0.021 14.4 0.3 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KXZ48458.1 - 0.027 14.0 0.4 6.2 6.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 KXZ48458.1 - 0.048 13.4 0.4 2.8 7.7 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KXZ48458.1 - 0.075 13.0 0.1 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXZ48458.1 - 0.082 13.4 0.1 4.1 8.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KXZ48458.1 - 0.096 12.6 0.4 0.75 9.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.6 KXZ48458.1 - 0.1 12.8 0.0 28 5.0 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KXZ48458.1 - 0.1 12.8 1.3 14 5.9 0.1 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KXZ48458.1 - 0.11 12.4 1.5 2.4 8.1 0.1 2.7 3 0 0 3 3 2 0 NACHT domain NTPase_1 PF03266.15 KXZ48458.1 - 0.13 12.2 2.0 6.1 6.7 0.1 2.8 3 0 0 3 3 2 0 NTPase AAA_24 PF13479.6 KXZ48458.1 - 0.14 11.8 0.0 0.73 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXZ48458.1 - 0.21 12.0 0.3 21 5.6 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KXZ48458.1 - 0.51 9.6 3.2 9.4 5.5 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin EF-hand_1 PF00036.32 KXZ48459.1 - 3.8e-28 94.9 7.5 2.1e-07 30.0 0.5 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ48459.1 - 7.8e-27 93.5 0.7 6.4e-15 55.4 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ48459.1 - 3.8e-22 76.3 5.5 2.3e-05 24.0 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXZ48459.1 - 1.9e-18 65.0 8.4 1.5e-06 27.4 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXZ48459.1 - 2.3e-13 49.8 6.3 8.2e-06 25.6 0.3 4.8 2 1 3 5 5 5 3 EF-hand domain pair Thioredoxin PF00085.20 KXZ48459.1 - 1.4e-11 44.3 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin EF-hand_4 PF12763.7 KXZ48459.1 - 9.9e-07 28.7 1.0 0.33 10.9 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Thioredoxin_2 PF13098.6 KXZ48459.1 - 7.6e-05 23.1 0.1 0.0002 21.8 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ48459.1 - 0.00095 19.4 0.1 0.0075 16.6 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like EF-hand_9 PF14658.6 KXZ48459.1 - 0.0012 19.1 0.0 0.33 11.3 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KXZ48459.1 - 0.02 15.1 0.0 10 6.4 0.0 2.7 3 0 0 3 3 2 0 Dockerin type I domain DUF2847 PF11009.8 KXZ48459.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AhpC-TSA PF00578.21 KXZ48459.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DUF608 PF04685.13 KXZ48459.1 - 0.066 12.4 0.1 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyl-hydrolase family 116, catalytic region TraF PF13728.6 KXZ48459.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KXZ48459.1 - 0.19 11.9 0.1 0.45 10.7 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like AAA PF00004.29 KXZ48460.1 - 4e-39 134.1 0.0 9.3e-14 52.0 0.0 3.4 2 1 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ48460.1 - 8.1e-21 73.6 10.6 7.2e-12 44.9 0.1 3.9 4 0 0 4 4 4 2 AAA+ lid domain Nucleolin_bd PF16725.5 KXZ48460.1 - 1.6e-14 53.3 0.4 3.1e-14 52.4 0.4 1.5 1 0 0 1 1 1 1 Nucleolin binding domain RuvB_N PF05496.12 KXZ48460.1 - 1.4e-06 28.1 0.0 1.6e-05 24.7 0.0 2.5 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ48460.1 - 8.4e-06 26.3 0.1 5.6e-05 23.6 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXZ48460.1 - 0.0003 20.8 0.0 0.015 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 KXZ48460.1 - 0.0004 20.3 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 KXZ48460.1 - 0.003 17.9 0.0 0.01 16.2 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_22 PF13401.6 KXZ48460.1 - 0.0042 17.4 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ48460.1 - 0.0051 17.0 0.1 0.024 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXZ48460.1 - 0.0067 16.2 0.0 0.022 14.5 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KXZ48460.1 - 0.0074 15.5 0.0 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_17 PF13207.6 KXZ48460.1 - 0.0079 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXZ48460.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KXZ48460.1 - 0.025 15.1 0.0 0.054 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXZ48460.1 - 0.026 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KXZ48460.1 - 0.038 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.6 KXZ48460.1 - 0.041 14.0 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KXZ48460.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXZ48460.1 - 0.08 12.5 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXZ48460.1 - 0.084 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXZ48460.1 - 0.087 12.2 0.9 0.4 10.0 0.0 2.3 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.22 KXZ48460.1 - 0.16 11.1 0.0 0.56 9.3 0.0 1.9 3 0 0 3 3 3 0 NB-ARC domain Parvo_NS1 PF01057.17 KXZ48460.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KXZ48460.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Ank_4 PF13637.6 KXZ48461.1 - 9.5e-08 32.4 0.0 0.93 10.2 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48461.1 - 7.4e-07 29.0 0.0 2.1 9.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KXZ48461.1 - 0.00032 21.2 0.1 0.35 11.5 0.0 3.6 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ48461.1 - 0.018 15.3 0.1 1.9 8.9 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PPR_2 PF13041.6 KXZ48461.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family AAA_2 PF07724.14 KXZ48462.1 - 5.3e-56 189.4 0.0 7.3e-53 179.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 KXZ48462.1 - 3.5e-23 81.4 0.2 1.2e-22 79.7 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KXZ48462.1 - 2.1e-18 67.0 0.0 1.5e-08 35.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ48462.1 - 2.7e-15 56.6 0.1 1.8e-11 44.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ48462.1 - 1.3e-11 45.2 11.8 1.1e-06 29.1 0.1 5.1 4 1 0 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KXZ48462.1 - 3.2e-09 36.7 0.0 2.2e-06 27.5 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KXZ48462.1 - 2.7e-07 31.0 2.8 0.028 14.7 0.2 4.2 4 1 0 4 4 2 2 AAA domain IstB_IS21 PF01695.17 KXZ48462.1 - 2.3e-06 27.4 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KXZ48462.1 - 4.9e-06 26.6 0.1 0.012 15.6 0.0 3.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KXZ48462.1 - 1.1e-05 25.4 0.0 0.0051 16.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 KXZ48462.1 - 1.2e-05 24.9 0.0 0.034 13.7 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region TniB PF05621.11 KXZ48462.1 - 1.8e-05 24.3 0.0 0.81 9.1 0.0 3.6 3 0 0 3 3 3 2 Bacterial TniB protein RsgA_GTPase PF03193.16 KXZ48462.1 - 5.6e-05 23.1 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 KXZ48462.1 - 0.00011 22.5 0.1 0.49 10.8 0.0 3.1 3 0 0 3 3 3 2 RNA helicase Roc PF08477.13 KXZ48462.1 - 0.00014 22.1 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KXZ48462.1 - 0.00015 22.3 1.2 0.038 14.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KXZ48462.1 - 0.00042 20.5 1.4 0.16 12.1 0.0 3.4 4 0 0 4 4 3 1 AAA domain TsaE PF02367.17 KXZ48462.1 - 0.00044 20.2 0.0 0.74 9.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXZ48462.1 - 0.0008 19.2 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KXZ48462.1 - 0.0011 19.5 0.0 0.91 10.0 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KXZ48462.1 - 0.0028 18.2 2.4 0.89 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 KXZ48462.1 - 0.0053 16.9 1.1 5.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain ResIII PF04851.15 KXZ48462.1 - 0.0094 16.0 0.0 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KXZ48462.1 - 0.011 15.8 0.0 0.23 11.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KXZ48462.1 - 0.011 15.4 0.0 0.59 9.9 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KXZ48462.1 - 0.016 15.0 0.0 9.4 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 KXZ48462.1 - 0.017 15.0 0.0 5.5 6.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_25 PF13481.6 KXZ48462.1 - 0.017 14.7 0.1 2.3 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXZ48462.1 - 0.018 14.4 0.0 0.23 10.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KXZ48462.1 - 0.058 12.8 0.0 0.77 9.1 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.6 KXZ48462.1 - 0.078 12.8 0.0 0.49 10.2 0.0 2.1 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Tup_N PF08581.10 KXZ48462.1 - 0.093 13.0 0.4 0.23 11.8 0.4 1.6 1 0 0 1 1 1 0 Tup N-terminal PhoH PF02562.16 KXZ48462.1 - 0.093 12.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Cep57_MT_bd PF06657.13 KXZ48462.1 - 0.097 13.1 3.2 0.37 11.3 3.2 2.0 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Ras PF00071.22 KXZ48462.1 - 0.11 12.1 0.0 6.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.6 KXZ48462.1 - 0.12 12.6 7.5 1.3 9.2 0.0 3.8 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KXZ48462.1 - 0.14 11.9 0.0 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KXZ48462.1 - 0.18 11.4 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF3584 PF12128.8 KXZ48462.1 - 1.4 6.3 13.1 2 5.9 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SLX9 PF15341.6 KXZ48462.1 - 1.5 9.2 9.0 21 5.5 8.7 2.2 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Peptidase_S46 PF10459.9 KXZ48462.1 - 3.2 6.3 5.1 5 5.6 5.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Herpes_UL52 PF03121.15 KXZ48463.1 - 2.5e-07 30.5 0.6 6e-07 29.3 0.6 1.5 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase CENP-B_dimeris PF09026.10 KXZ48463.1 - 0.66 10.4 4.1 1.6 9.2 4.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRP PF06011.12 KXZ48464.1 - 1.4e-06 27.4 7.5 1.7e-06 27.1 7.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF5562 PF17717.1 KXZ48464.1 - 0.037 14.0 1.0 0.037 14.0 1.0 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5562) Chlam_PMP PF02415.17 KXZ48465.1 - 3.3 8.4 37.8 0.52 10.9 2.2 6.8 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat EF-hand_1 PF00036.32 KXZ48467.1 - 3.1e-05 23.2 0.3 7.8e-05 22.0 0.1 1.9 1 1 1 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXZ48467.1 - 0.00075 18.9 0.1 0.0017 17.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ48467.1 - 0.0019 18.0 0.1 0.005 16.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ48467.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KXZ48467.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair Ricin_B_lectin PF00652.22 KXZ48469.1 - 1.1e-06 29.0 0.0 1.2e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXZ48469.1 - 0.0013 19.5 0.0 0.0014 19.3 0.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Enolase_C PF00113.22 KXZ48469.1 - 0.22 10.7 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain EF-hand_1 PF00036.32 KXZ48471.1 - 8.2e-05 21.9 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ48471.1 - 0.00021 21.0 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXZ48471.1 - 0.00054 19.3 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ48471.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 KXZ48471.1 - 0.053 14.0 0.0 0.069 13.6 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain pair TssO PF17561.2 KXZ48471.1 - 0.15 12.2 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO CDC73_C PF05179.14 KXZ48472.1 - 1.4e-39 135.3 0.0 2.7e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KXZ48472.1 - 1.6e-16 60.5 0.0 3.7e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal Ank_5 PF13857.6 KXZ48475.1 - 3.5e-08 33.6 0.3 4.5e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48475.1 - 3.4e-05 24.3 0.1 4.3e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48475.1 - 0.00016 22.2 0.0 0.00028 21.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48475.1 - 0.0016 18.8 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 KXZ48475.1 - 0.0017 18.8 1.0 0.0042 17.5 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Pkinase_Tyr PF07714.17 KXZ48476.1 - 3e-30 105.4 0.0 3.9e-29 101.7 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ48476.1 - 2.5e-25 89.4 0.0 2.5e-11 43.4 0.0 3.9 2 2 1 3 3 3 3 Protein kinase domain Pkinase PF00069.25 KXZ48477.1 - 2.8e-07 30.2 0.0 4.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48477.1 - 7.3e-07 28.7 0.0 4.1e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ48478.1 - 2.8e-11 43.2 0.0 9.5e-09 34.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ48478.1 - 9.4e-11 41.6 0.0 9.9e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Leu_zip PF15294.6 KXZ48479.1 - 1.7e-25 90.1 17.1 2.3e-25 89.6 17.1 1.2 1 0 0 1 1 1 1 Leucine zipper HMMR_N PF15905.5 KXZ48479.1 - 0.0003 20.4 20.5 0.00057 19.5 20.5 1.5 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 KXZ48479.1 - 0.0013 19.3 6.4 0.0013 19.3 6.4 3.7 2 2 1 3 3 2 1 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KXZ48479.1 - 0.0067 16.7 3.6 0.0067 16.7 3.6 4.4 3 1 1 4 4 4 1 ABC transporter C-terminal domain Spc7 PF08317.11 KXZ48479.1 - 0.007 15.3 15.0 0.007 15.3 15.0 2.6 1 1 3 4 4 4 2 Spc7 kinetochore protein T3SS_needle_F PF09392.10 KXZ48479.1 - 0.03 14.5 1.4 0.03 14.5 1.4 3.8 1 1 2 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF HIP1_clath_bdg PF16515.5 KXZ48479.1 - 0.031 14.9 30.0 0.24 12.0 6.5 3.3 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MPS2 PF17060.5 KXZ48479.1 - 0.042 13.1 6.1 0.04 13.2 1.8 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 PKcGMP_CC PF16808.5 KXZ48479.1 - 0.044 13.6 5.2 0.048 13.5 0.3 3.3 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sec34 PF04136.15 KXZ48479.1 - 0.23 11.3 6.1 4.3 7.2 1.3 2.8 2 0 0 2 2 2 0 Sec34-like family PNPase PF03726.14 KXZ48479.1 - 0.31 11.5 0.1 0.31 11.5 0.1 3.1 2 1 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Atg14 PF10186.9 KXZ48479.1 - 0.51 9.4 15.9 0.043 12.9 5.6 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KXZ48479.1 - 0.52 10.5 31.5 2.7 8.1 30.0 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 KXZ48479.1 - 0.56 10.4 11.6 4.7 7.5 0.7 3.5 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II CEP63 PF17045.5 KXZ48479.1 - 1.1 9.1 19.7 0.12 12.2 3.7 3.0 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa SOGA PF11365.8 KXZ48479.1 - 2.1 9.5 15.0 52 5.1 8.1 3.6 2 1 1 3 3 2 0 Protein SOGA TMF_TATA_bd PF12325.8 KXZ48479.1 - 2.4 8.4 17.8 0.94 9.7 4.5 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CENP-K PF11802.8 KXZ48479.1 - 2.6 7.5 13.7 1.4 8.5 10.5 1.9 1 1 1 2 2 2 0 Centromere-associated protein K DUF4201 PF13870.6 KXZ48479.1 - 3 7.5 22.5 0.83 9.4 8.6 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4201) Spectrin PF00435.21 KXZ48479.1 - 3.8 8.0 19.8 1.2 9.7 5.3 2.8 1 1 1 2 2 2 0 Spectrin repeat DUF4200 PF13863.6 KXZ48479.1 - 6.8 7.1 26.6 0.74 10.2 7.2 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.14 KXZ48479.1 - 7.9 6.8 36.9 6.1 7.2 14.1 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) RicinB_lectin_2 PF14200.6 KXZ48480.1 - 1.4e-56 189.2 26.9 1e-17 64.6 0.7 4.6 1 1 4 5 5 5 5 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ48480.1 - 2e-38 131.5 8.4 8.1e-14 52.0 0.6 3.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ48480.1 - 4.6e-17 62.7 1.3 4.6e-17 62.7 1.3 1.8 2 0 0 2 2 2 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ48480.1 - 5.9e-11 42.2 7.1 1.6e-07 31.0 0.4 3.7 1 1 2 3 3 3 3 Cytolethal distending toxin A/C domain EF-hand_1 PF00036.32 KXZ48481.1 - 3.1e-05 23.2 1.7 3.5e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 EF hand VOMI PF03762.17 KXZ48481.1 - 0.00021 21.5 0.2 0.00065 19.9 0.2 1.7 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) EF-hand_6 PF13405.6 KXZ48481.1 - 0.0008 19.2 0.0 0.0028 17.4 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ48481.1 - 0.0049 17.3 0.1 0.0096 16.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ48481.1 - 0.008 15.6 0.1 0.008 15.6 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXZ48481.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Hydrolase_4 PF12146.8 KXZ48482.1 - 0.00046 19.5 0.0 0.092 12.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ48482.1 - 0.0035 17.0 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold RicinB_lectin_2 PF14200.6 KXZ48483.1 - 1.5e-16 60.9 4.8 2e-11 44.5 0.3 4.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like VOMI PF03762.17 KXZ48483.1 - 1.8e-16 60.7 3.4 5.6e-16 59.1 3.4 1.8 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) Ricin_B_lectin PF00652.22 KXZ48483.1 - 5.8e-14 52.4 2.7 4.9e-13 49.4 0.7 2.9 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain EF-hand_1 PF00036.32 KXZ48483.1 - 0.0065 15.9 0.1 0.021 14.4 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ48483.1 - 0.016 15.1 0.1 0.053 13.5 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain CDtoxinA PF03498.14 KXZ48483.1 - 0.031 13.9 0.2 0.094 12.3 0.1 1.8 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain EF-hand_5 PF13202.6 KXZ48483.1 - 1.8 8.2 3.3 0.67 9.6 0.2 1.9 2 0 0 2 2 2 0 EF hand Ank_2 PF12796.7 KXZ48484.1 - 9.4e-165 535.7 56.6 1.3e-18 67.4 0.1 12.3 3 3 10 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48484.1 - 1e-129 421.4 28.8 6.8e-12 45.7 0.0 17.2 9 5 6 16 16 16 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48484.1 - 3.4e-117 381.0 66.5 2.4e-11 43.6 0.3 20.5 5 3 18 23 23 23 22 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48484.1 - 2.6e-114 369.1 70.9 4e-06 27.0 0.0 24.9 22 2 2 24 24 24 24 Ankyrin repeat Ank_3 PF13606.6 KXZ48484.1 - 2.4e-112 353.1 38.5 1.8e-05 24.7 0.0 25.9 25 0 0 25 25 25 22 Ankyrin repeat LRR_6 PF13516.6 KXZ48484.1 - 7.7e-10 38.0 5.8 0.017 15.1 0.1 6.5 8 0 0 8 8 8 2 Leucine Rich repeat XK-related PF09815.9 KXZ48484.1 - 5.8e-07 28.9 0.5 9.1e-07 28.2 0.5 1.2 1 0 0 1 1 1 1 XK-related protein DUF2188 PF09954.9 KXZ48484.1 - 0.018 15.2 0.2 0.087 13.0 0.2 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Peptidase_S8 PF00082.22 KXZ48485.1 - 1e-31 110.3 0.0 1.7e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Metallophos_2 PF12850.7 KXZ48487.1 - 4.4e-15 56.3 0.0 6.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KXZ48487.1 - 0.048 14.2 0.6 1.3 9.5 0.2 2.3 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase CAP PF00188.26 KXZ48488.1 - 1e-11 45.7 0.0 3e-08 34.6 0.0 3.5 1 1 2 3 3 3 1 Cysteine-rich secretory protein family Ricin_B_lectin PF00652.22 KXZ48488.1 - 2.4e-10 40.8 2.4 0.013 15.8 0.0 4.4 4 0 0 4 4 4 3 Ricin-type beta-trefoil lectin domain Spermine_synt_N PF17284.2 KXZ48488.1 - 9e-05 22.3 0.0 5.5 7.0 0.0 4.0 4 0 0 4 4 4 2 Spermidine synthase tetramerisation domain DUF916 PF06030.12 KXZ48488.1 - 0.24 11.5 0.3 11 6.1 0.1 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF916) Spermine_synt_N PF17284.2 KXZ48489.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain DUF5368 PF17336.2 KXZ48490.1 - 0.21 11.8 2.2 0.33 11.1 2.2 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5368) RTC_insert PF05189.13 KXZ48492.1 - 1.3 9.6 6.2 0.65 10.5 0.5 2.8 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ank_3 PF13606.6 KXZ48493.1 - 2.7e-06 27.3 0.4 17 6.4 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 KXZ48493.1 - 7.8e-05 23.2 0.0 3 8.5 0.0 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48493.1 - 0.04 14.5 0.0 3.5 8.3 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ48493.1 - 0.11 12.8 0.1 70 3.9 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48494.1 - 6.8e-07 29.8 0.1 0.01 16.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ48494.1 - 0.0036 17.6 4.2 2.7 8.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ48494.1 - 0.0044 17.6 0.3 3.6 8.3 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48494.1 - 0.0083 16.6 1.2 41 5.2 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 KXZ48494.1 - 0.26 11.8 0.9 1.8e+02 2.8 0.0 3.9 3 1 0 3 3 3 0 Ankyrin repeat UCH PF00443.29 KXZ48495.1 - 3.4e-23 82.4 0.0 1.1e-21 77.5 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3761 PF12587.8 KXZ48495.1 - 0.0091 16.4 0.5 0.046 14.1 0.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3761) Mito_fiss_reg PF05308.11 KXZ48495.1 - 0.012 15.7 9.5 0.044 13.9 0.1 3.9 4 0 0 4 4 4 0 Mitochondrial fission regulator KNOX1 PF03790.13 KXZ48495.1 - 0.072 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 KNOX1 domain Autophagy_N PF03986.13 KXZ48496.1 - 3.1e-39 134.0 0.0 4.6e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KXZ48496.1 - 8.2e-18 64.7 0.2 1.8e-17 63.6 0.2 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KXZ48496.1 - 5.6e-16 57.7 2.9 1e-15 56.9 2.9 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Dioxygenase_N PF04444.14 KXZ48496.1 - 0.17 11.8 0.1 28 4.7 0.0 2.3 2 0 0 2 2 2 0 Catechol dioxygenase N terminus TrbI PF03743.14 KXZ48496.1 - 0.24 11.2 2.0 0.36 10.6 2.0 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Myb_DNA-binding PF00249.31 KXZ48497.1 - 0.0011 19.1 1.0 0.0024 18.0 1.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Ank_2 PF12796.7 KXZ48498.1 - 1.9e-49 166.1 4.2 4.5e-11 43.2 0.1 6.4 1 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ48498.1 - 1e-33 114.9 5.8 0.00032 20.9 0.0 9.9 4 3 7 11 11 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ48498.1 - 6.4e-32 109.5 0.3 1.4e-07 31.9 0.0 8.2 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48498.1 - 5.4e-31 103.2 1.1 0.0016 18.7 0.0 11.9 12 1 1 13 13 13 6 Ankyrin repeat Ank PF00023.30 KXZ48498.1 - 1.7e-27 94.6 2.4 0.0015 18.9 0.0 10.2 11 1 0 11 11 11 6 Ankyrin repeat ABC_tran PF00005.27 KXZ48499.1 - 1.7e-21 77.1 0.0 2.8e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXZ48499.1 - 0.00022 21.2 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KXZ48499.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXZ48499.1 - 0.0071 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KXZ48499.1 - 0.0092 15.8 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ48499.1 - 0.011 15.5 0.2 0.054 13.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXZ48499.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXZ48499.1 - 0.015 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ48499.1 - 0.022 15.1 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXZ48499.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KXZ48499.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SMC_N PF02463.19 KXZ48499.1 - 0.029 13.8 0.0 0.32 10.4 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 KXZ48499.1 - 0.037 14.4 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KXZ48499.1 - 0.042 14.3 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 KXZ48499.1 - 0.045 12.6 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_23 PF13476.6 KXZ48499.1 - 0.049 14.1 0.0 0.08 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXZ48499.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXZ48499.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_19 PF04672.12 KXZ48500.1 - 0.22 11.0 0.6 19 4.6 0.1 2.1 2 0 0 2 2 2 0 S-adenosyl methyltransferase Peptidase_M11 PF05548.11 KXZ48503.1 - 0.061 12.5 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Gametolysin peptidase M11 Peptidase_S8 PF00082.22 KXZ48504.1 - 7.3e-12 45.1 0.0 8.5e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_M11 PF05548.11 KXZ48505.1 - 9.2e-10 38.2 0.0 3.6e-05 23.1 0.0 2.4 2 1 0 2 2 2 2 Gametolysin peptidase M11 Reprolysin_3 PF13582.6 KXZ48505.1 - 0.0012 19.3 0.0 0.0023 18.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXZ48505.1 - 0.052 13.7 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KXZ48505.1 - 0.054 12.4 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 KXZ48505.1 - 0.09 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 KXZ48505.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like 2OG-Fe_Oxy_2 PF10014.9 KXZ48505.1 - 0.19 11.5 0.1 21 4.9 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe dioxygenase Reprolysin PF01421.19 KXZ48505.1 - 0.19 11.6 0.1 0.28 11.1 0.1 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease zf-MYND PF01753.18 KXZ48509.1 - 3.6e-06 27.0 8.7 7e-06 26.0 8.7 1.5 1 0 0 1 1 1 1 MYND finger HRM PF02793.22 KXZ48510.1 - 0.21 11.9 6.6 0.5 10.7 6.6 1.7 1 1 0 1 1 1 0 Hormone receptor domain ABC_tran PF00005.27 KXZ48511.1 - 8.4e-25 87.9 0.0 1.1e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXZ48511.1 - 2.2e-05 24.4 0.1 3.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KXZ48511.1 - 8.1e-05 22.6 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXZ48511.1 - 0.00083 19.9 1.1 0.0012 19.4 1.1 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXZ48511.1 - 0.0012 19.3 0.0 0.061 13.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXZ48511.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 KXZ48511.1 - 0.0024 18.1 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXZ48511.1 - 0.0051 16.2 0.0 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 KXZ48511.1 - 0.0082 15.6 0.1 1.2 8.5 0.4 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KXZ48511.1 - 0.013 16.1 0.0 0.021 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ48511.1 - 0.017 15.5 0.0 0.023 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXZ48511.1 - 0.029 14.7 0.0 0.07 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXZ48511.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KXZ48511.1 - 0.041 13.6 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KXZ48511.1 - 0.062 13.7 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 KXZ48511.1 - 0.081 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain PSK_trans_fac PF07704.11 KXZ48511.1 - 0.085 13.6 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Rv0623-like transcription factor ATP_bind_1 PF03029.17 KXZ48511.1 - 0.088 12.6 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KXZ48511.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KXZ48511.1 - 0.091 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXZ48511.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 KXZ48511.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KXZ48511.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KXZ48511.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF3270 PF11674.8 KXZ48512.1 - 0.12 12.6 0.6 0.25 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Ank_4 PF13637.6 KXZ48513.1 - 1.3e-11 44.8 0.6 0.00098 19.7 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48513.1 - 1.8e-09 38.0 0.0 0.0047 17.5 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48513.1 - 1.6e-07 31.1 0.3 10 7.0 0.0 5.9 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KXZ48513.1 - 0.00056 20.2 0.7 20 5.7 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeats (many copies) DUF5635 PF18685.1 KXZ48513.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Defensin_4 PF07936.12 KXZ48513.1 - 0.17 11.8 2.1 26 4.8 0.0 3.7 3 0 0 3 3 3 0 Potassium-channel blocking toxin Cullin PF00888.22 KXZ48514.1 - 4.1e-166 554.2 10.3 8.6e-125 417.7 9.2 2.2 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 KXZ48514.1 - 4.7e-27 93.8 6.4 4.7e-27 93.8 6.4 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Ku_C PF03730.14 KXZ48514.1 - 0.051 14.3 2.1 3 8.6 0.3 3.2 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm PCI PF01399.27 KXZ48514.1 - 3.4 8.2 5.8 5.5 7.6 0.1 3.5 4 0 0 4 4 4 0 PCI domain Ank_2 PF12796.7 KXZ48515.1 - 6.1e-43 145.3 6.5 1.9e-12 47.6 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ48515.1 - 6.2e-36 121.3 14.1 4e-07 30.2 0.1 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KXZ48515.1 - 2e-34 113.7 4.2 6.3e-05 23.1 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KXZ48515.1 - 5.3e-33 113.0 4.0 1.5e-12 47.8 0.1 3.9 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48515.1 - 4.6e-32 109.7 6.8 9.1e-09 35.4 0.1 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) TIR_2 PF13676.6 KXZ48515.1 - 1.4e-05 25.6 0.0 2.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 TIR domain EF-hand_1 PF00036.32 KXZ48516.1 - 9.5e-13 46.7 0.3 1.4e-07 30.5 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KXZ48516.1 - 2.9e-10 39.8 0.4 2.5e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KXZ48516.1 - 1.2e-09 38.5 0.3 1.6e-08 34.9 0.2 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ48516.1 - 5e-08 32.2 1.4 0.0071 16.2 0.0 3.6 3 2 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KXZ48516.1 - 1.5e-05 24.3 0.5 0.14 11.7 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KXZ48516.1 - 0.0014 19.0 0.0 0.0077 16.5 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain Peptidase_M16 PF00675.20 KXZ48518.1 - 5.3e-40 136.8 0.0 6.5e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 KXZ48519.1 - 1.7e-08 34.2 0.0 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Sec3_C PF09763.9 KXZ48521.1 - 5.1e-23 81.4 0.0 5.7e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Vps52 PF04129.12 KXZ48521.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family APG17 PF04108.12 KXZ48521.1 - 0.21 10.7 0.3 0.34 10.0 0.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 FlgN PF05130.12 KXZ48521.1 - 3.3 8.2 5.4 3.5 8.1 2.5 2.5 2 1 0 2 2 2 0 FlgN protein Ribosomal_L3 PF00297.22 KXZ48522.1 - 7.3e-20 71.3 9.4 1.6e-19 70.2 3.1 2.6 1 1 2 3 3 3 2 Ribosomal protein L3 DUF2790 PF10976.8 KXZ48522.1 - 0.049 13.6 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) zf-MYND PF01753.18 KXZ48523.1 - 6.5e-07 29.3 10.1 1.3e-06 28.4 10.1 1.5 1 0 0 1 1 1 1 MYND finger SOR_SNZ PF01680.17 KXZ48526.1 - 2.4e-112 373.7 7.4 3.3e-112 373.3 7.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KXZ48526.1 - 2.9e-09 36.6 7.4 7.6e-07 28.7 0.4 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KXZ48526.1 - 5.2e-05 22.5 0.8 0.075 12.1 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KXZ48526.1 - 0.0001 21.6 0.8 0.027 13.6 0.0 2.5 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 KXZ48526.1 - 0.00013 21.9 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 KXZ48526.1 - 0.00082 18.9 2.3 0.49 9.8 0.0 3.6 4 0 0 4 4 4 1 Histidine biosynthesis protein NMO PF03060.15 KXZ48526.1 - 0.03 13.7 7.8 0.19 11.1 0.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.21 KXZ48526.1 - 0.031 13.5 0.1 0.62 9.2 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase IMPDH PF00478.25 KXZ48526.1 - 0.076 12.0 2.3 0.3 10.1 2.2 2.0 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain OMPdecase PF00215.24 KXZ48526.1 - 0.14 11.7 1.2 0.25 10.9 0.1 2.0 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Pkinase PF00069.25 KXZ48527.1 - 1.3e-16 60.7 0.0 2.5e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48527.1 - 7.2e-13 48.4 0.0 3.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase WD40 PF00400.32 KXZ48528.1 - 1.2e-20 73.4 0.0 3.1e-05 24.6 0.2 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ48528.1 - 6.4e-12 45.6 0.0 4.6e-05 23.6 0.0 3.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ48528.1 - 3.4e-06 26.3 0.0 0.038 12.9 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXZ48528.1 - 0.033 13.5 0.1 2.4 7.4 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3761 PF12587.8 KXZ48528.1 - 0.11 12.9 0.0 0.47 10.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) Glyco_transf_92 PF01697.27 KXZ48529.1 - 5.3e-14 52.5 1.0 7.2e-14 52.1 1.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KXZ48529.1 - 2.5e-09 37.5 0.4 4.6e-09 36.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 KXZ48530.1 - 5.9e-09 36.0 0.0 6.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KXZ48530.1 - 0.013 16.0 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 NUDIX PF00293.28 KXZ48532.1 - 5.5e-09 36.2 0.6 3.9e-07 30.2 0.8 2.1 2 0 0 2 2 2 2 NUDIX domain Trimer_CC PF08954.11 KXZ48533.1 - 0.0036 16.8 2.9 0.95 9.1 0.0 2.6 2 0 0 2 2 2 2 Trimerisation motif DUF1213 PF06740.12 KXZ48533.1 - 0.035 14.7 0.5 0.16 12.5 0.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1213) TPR_12 PF13424.6 KXZ48534.1 - 1.4e-05 25.3 5.1 0.0004 20.6 4.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ48534.1 - 1.6e-05 24.5 2.1 0.0038 17.0 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ48534.1 - 0.00024 20.9 0.8 0.92 9.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ48534.1 - 0.0039 17.2 7.5 0.16 12.2 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 KXZ48534.1 - 0.0072 16.4 0.9 0.012 15.7 0.9 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 KXZ48534.1 - 0.16 12.7 1.0 17 6.3 0.0 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF1488 PF07369.11 KXZ48534.1 - 0.2 11.6 1.4 0.59 10.2 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) TPR_10 PF13374.6 KXZ48534.1 - 1.5 8.8 4.0 1 9.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_2 PF07724.14 KXZ48535.1 - 8e-59 198.6 0.1 2.5e-56 190.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.20 KXZ48535.1 - 1.7e-39 133.7 2.4 4.5e-19 68.3 0.2 2.8 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_lid_9 PF17871.1 KXZ48535.1 - 7.6e-34 115.8 0.5 1.7e-33 114.6 0.5 1.6 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 KXZ48535.1 - 1.3e-24 86.0 0.2 4.6e-24 84.3 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KXZ48535.1 - 1.5e-23 83.6 0.3 1.8e-13 51.1 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ48535.1 - 1.8e-18 66.9 1.1 1.3e-11 44.7 0.0 3.7 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ48535.1 - 1.2e-10 42.0 1.6 3.7e-05 24.2 0.1 4.0 3 1 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KXZ48535.1 - 3.2e-09 36.7 0.1 1.2e-05 25.0 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain UVR PF02151.19 KXZ48535.1 - 1e-07 31.5 1.1 3.3e-07 29.8 1.1 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif AAA_22 PF13401.6 KXZ48535.1 - 1.5e-07 31.8 5.0 0.026 14.8 0.5 5.4 4 2 0 4 4 3 2 AAA domain TniB PF05621.11 KXZ48535.1 - 2.5e-07 30.3 0.0 0.00037 20.0 0.0 4.2 4 1 0 4 4 3 1 Bacterial TniB protein IstB_IS21 PF01695.17 KXZ48535.1 - 2.4e-06 27.4 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KXZ48535.1 - 3.9e-06 27.4 0.2 0.08 13.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KXZ48535.1 - 2.9e-05 24.1 0.0 0.3 11.1 0.0 3.2 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXZ48535.1 - 5.4e-05 23.5 0.2 0.75 10.2 0.0 3.0 2 1 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 KXZ48535.1 - 6.9e-05 22.2 0.0 0.02 14.2 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 KXZ48535.1 - 0.00012 22.0 0.0 0.012 15.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 KXZ48535.1 - 0.00013 21.5 0.3 0.89 8.9 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXZ48535.1 - 0.00014 21.5 0.0 0.019 14.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KXZ48535.1 - 0.00024 20.9 0.2 0.7 9.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXZ48535.1 - 0.00033 20.6 0.2 0.46 10.4 0.0 2.7 2 1 1 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 KXZ48535.1 - 0.00049 20.3 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KXZ48535.1 - 0.00059 19.9 0.1 1.9 8.5 0.0 3.7 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KXZ48535.1 - 0.0012 18.6 8.1 3.2 7.5 0.0 5.2 3 2 1 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXZ48535.1 - 0.0019 17.7 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 KXZ48535.1 - 0.0034 17.3 0.1 0.63 9.9 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXZ48535.1 - 0.006 16.4 0.0 1.5 8.5 0.0 3.0 3 0 0 3 3 3 1 DNA polymerase III, delta subunit TsaE PF02367.17 KXZ48535.1 - 0.0068 16.4 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXZ48535.1 - 0.0071 16.6 0.2 6.8 6.9 0.1 3.4 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KXZ48535.1 - 0.014 15.6 0.0 6.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXZ48535.1 - 0.018 15.5 0.0 1.8 9.1 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Torsin PF06309.11 KXZ48535.1 - 0.021 14.9 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 0 Torsin DUF815 PF05673.13 KXZ48535.1 - 0.026 13.7 0.1 8.2 5.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 KXZ48535.1 - 0.027 13.4 0.4 1.1 8.1 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.23 KXZ48535.1 - 0.05 13.7 0.3 21 5.3 0.0 3.3 3 1 0 3 3 3 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 KXZ48535.1 - 0.074 13.0 5.8 17 5.2 0.1 4.0 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea CLP1_P PF16575.5 KXZ48535.1 - 0.093 12.5 0.0 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop KTI12 PF08433.10 KXZ48535.1 - 0.16 11.4 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Pkinase PF00069.25 KXZ48536.1 - 3e-44 151.4 0.0 4.3e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48536.1 - 6.4e-40 137.1 0.0 9.6e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ48536.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ48536.1 - 0.03 13.1 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ48537.1 - 6.3e-39 133.9 0.0 4.3e-36 124.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48537.1 - 6.9e-33 114.0 0.0 2.7e-30 105.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_N PF01213.19 KXZ48537.1 - 0.65 9.4 3.1 1.1 8.7 3.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Exostosin PF03016.15 KXZ48538.1 - 1.9e-42 145.5 0.2 1.4e-20 73.7 0.0 2.2 1 1 1 2 2 2 2 Exostosin family EGF_2 PF07974.13 KXZ48538.1 - 0.012 15.9 12.3 0.012 15.9 12.3 2.7 3 0 0 3 3 3 0 EGF-like domain RCC1_2 PF13540.6 KXZ48539.1 - 6.4e-43 143.7 30.6 8.5e-08 31.8 1.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXZ48539.1 - 8.7e-29 99.9 34.1 2.2e-05 25.0 0.4 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat PB1 PF00564.24 KXZ48541.1 - 0.00029 20.7 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 PB1 domain UPRTase PF14681.6 KXZ48543.1 - 8.9e-61 204.9 0.0 1.1e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXZ48543.1 - 0.00016 21.2 0.1 0.00037 20.0 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain VOMI PF03762.17 KXZ48544.1 - 2.9e-17 63.3 3.0 1e-12 48.6 0.8 2.3 2 1 1 3 3 3 2 Vitelline membrane outer layer protein I (VOMI) REJ PF02010.15 KXZ48545.1 - 5.9e-06 25.3 0.4 0.00013 20.9 0.1 2.5 1 1 1 2 2 2 2 REJ domain ARL2_Bind_BART PF11527.8 KXZ48546.1 - 2.6e-32 111.4 2.3 3.5e-32 110.9 2.3 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART MMR_HSR1 PF01926.23 KXZ48547.1 - 3.3e-22 78.7 0.0 4.9e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 KXZ48547.1 - 4.8e-16 58.4 0.4 9.4e-16 57.4 0.4 1.5 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 KXZ48547.1 - 2.4e-14 53.2 0.0 3.5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXZ48547.1 - 1.7e-09 37.9 0.1 3.3e-05 24.0 0.1 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KXZ48547.1 - 1.2e-06 28.6 0.0 0.0036 17.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KXZ48547.1 - 2.8e-05 23.6 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AIG1 PF04548.16 KXZ48547.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Arf PF00025.21 KXZ48547.1 - 0.001 18.6 0.0 0.0026 17.3 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXZ48547.1 - 0.0011 18.5 0.0 0.25 10.9 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KXZ48547.1 - 0.0012 18.5 0.0 0.0041 16.9 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KXZ48547.1 - 0.015 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 KXZ48547.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 KXZ48547.1 - 0.033 14.7 0.0 0.064 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KXZ48547.1 - 0.043 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KXZ48547.1 - 0.06 13.1 0.1 5.8 6.6 0.0 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 KXZ48547.1 - 0.13 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KXZ48547.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DHDPS PF00701.22 KXZ48548.1 - 2.2e-80 269.5 0.0 2.7e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF155 PF02582.14 KXZ48550.1 - 6e-09 36.2 0.1 8.1e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 TPM_phosphatase PF04536.14 KXZ48551.1 - 4.5e-06 26.8 0.0 7.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 TPM domain FAP PF07174.11 KXZ48551.1 - 0.044 13.3 0.2 0.071 12.6 0.2 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Adenylsucc_synt PF00709.21 KXZ48552.1 - 1.1e-173 578.0 0.0 1.3e-173 577.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CCDC92 PF14916.6 KXZ48552.1 - 0.024 14.4 0.2 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Aminotran_1_2 PF00155.21 KXZ48553.1 - 4.3e-37 128.1 0.0 7.1e-37 127.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KXZ48553.1 - 0.00028 19.9 0.0 0.001 18.1 0.0 1.8 2 0 0 2 2 2 1 Allinase Acetyltransf_1 PF00583.25 KXZ48554.1 - 1.7e-08 34.7 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXZ48554.1 - 2.6e-08 33.7 0.2 4.8e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KXZ48554.1 - 3e-07 30.4 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ48554.1 - 6.1e-06 26.6 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RskA PF10099.9 KXZ48554.1 - 2.7 8.3 35.7 0.36 11.1 8.8 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Ribosomal_L13e PF01294.18 KXZ48555.1 - 1.8e-67 226.7 3.4 2.5e-67 226.2 3.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF2118 PF09891.9 KXZ48555.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) eIF-1a PF01176.19 KXZ48556.1 - 2.3e-23 81.7 0.4 4e-23 81.0 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 UPF0051 PF01458.17 KXZ48557.1 - 2.5e-65 220.2 0.0 3.3e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) CHIPS PF11434.8 KXZ48557.1 - 0.1 12.5 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS TPT PF03151.16 KXZ48558.1 - 4.1e-12 46.1 25.9 4.9e-12 45.8 25.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Phyto-Amp PF15438.6 KXZ48558.1 - 0.02 14.7 0.3 0.02 14.7 0.3 2.7 3 0 0 3 3 3 0 Antigenic membrane protein of phytoplasma EamA PF00892.20 KXZ48558.1 - 0.23 11.6 37.4 0.1 12.7 12.9 2.7 1 1 2 3 3 3 0 EamA-like transporter family DUF3318 PF11780.8 KXZ48558.1 - 0.68 9.9 3.6 0.3 11.0 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) Brr6_like_C_C PF10104.9 KXZ48560.1 - 0.0045 16.8 0.3 0.0069 16.2 0.3 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain RskA PF10099.9 KXZ48560.1 - 0.01 16.1 3.9 0.013 15.8 3.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DcuC PF03606.15 KXZ48560.1 - 0.049 12.1 0.8 0.061 11.8 0.8 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier IBR PF01485.21 KXZ48561.1 - 1.5e-14 53.9 34.2 3e-08 33.8 8.8 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KXZ48561.1 - 0.075 12.9 0.1 0.075 12.9 0.1 5.2 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ48561.1 - 0.3 11.5 34.9 0.12 12.7 5.0 4.0 3 1 0 3 3 3 0 Ring finger domain Lipase_chap PF03280.14 KXZ48561.1 - 0.37 10.7 12.8 0.85 9.5 12.8 1.5 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein PRP21_like_P PF12230.8 KXZ48561.1 - 0.44 10.4 2.6 0.43 10.4 0.4 1.8 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-ACC PF17848.1 KXZ48561.1 - 3.7 7.7 9.8 1.8 8.7 3.8 2.8 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Ank_4 PF13637.6 KXZ48562.1 - 9.4e-15 54.8 2.9 0.0048 17.4 0.1 7.4 7 1 0 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48562.1 - 2.5e-13 50.4 0.1 0.0025 18.3 0.1 5.0 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48562.1 - 0.018 15.5 11.2 40 5.3 0.0 8.2 10 0 0 10 10 10 0 Ankyrin repeat Ank_5 PF13857.6 KXZ48562.1 - 4.2 7.8 11.1 3.7 8.0 0.1 5.5 6 1 2 8 8 8 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ48563.1 - 9.5e-09 35.6 2.6 2.8 8.6 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48563.1 - 6.3e-08 33.1 0.3 0.018 15.6 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48563.1 - 0.00032 20.9 0.6 72 4.5 0.0 5.6 5 0 0 5 5 5 0 Ankyrin repeat IBR PF01485.21 KXZ48564.1 - 3.2e-15 56.1 33.6 5.2e-08 33.0 1.7 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KXZ48564.1 - 0.24 11.3 0.1 0.24 11.3 0.1 4.7 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) COR PF16095.5 KXZ48565.1 - 2.8e-21 76.2 0.0 7.4e-21 74.8 0.0 1.7 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 KXZ48565.1 - 6.8e-12 45.7 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PAP2 PF01569.21 KXZ48565.1 - 1.2e-11 44.6 2.4 1.3e-10 41.2 1.2 2.8 2 0 0 2 2 2 1 PAP2 superfamily Ras PF00071.22 KXZ48565.1 - 8.3e-05 22.2 0.0 0.00019 21.0 0.0 1.6 2 0 0 2 2 2 1 Ras family IBR PF01485.21 KXZ48567.1 - 1.4e-08 34.8 7.4 3.7e-08 33.5 6.0 2.1 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain IBR PF01485.21 KXZ48568.1 - 1.4e-15 57.2 22.6 7.4e-08 32.5 5.6 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain DUF2396 PF09654.10 KXZ48568.1 - 0.0062 16.7 1.2 0.011 15.9 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2396) IBR PF01485.21 KXZ48569.1 - 9.9e-15 54.5 20.0 1e-07 32.1 5.2 2.7 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain IBR PF01485.21 KXZ48570.1 - 2.1e-11 43.8 20.6 1.3e-07 31.7 1.6 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXZ48570.1 - 0.00062 19.6 0.6 0.00062 19.6 0.6 4.6 3 3 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ48570.1 - 0.0076 16.6 0.3 0.0076 16.6 0.3 4.8 4 2 2 6 6 6 1 Ring finger domain zf-RING_UBOX PF13445.6 KXZ48570.1 - 0.013 15.5 2.2 0.013 15.5 2.2 3.9 3 1 0 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ48570.1 - 0.035 14.1 1.6 0.035 14.1 1.6 5.3 3 3 2 5 5 5 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXZ48570.1 - 0.038 13.8 0.5 0.038 13.8 0.5 4.9 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXZ48570.1 - 0.14 12.3 0.3 0.14 12.3 0.3 4.0 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING Serglycin PF04360.12 KXZ48570.1 - 0.34 10.8 1.8 0.52 10.2 1.8 1.2 1 0 0 1 1 1 0 Serglycin zf-RING_6 PF14835.6 KXZ48570.1 - 2.2 8.2 13.5 13 5.7 1.3 3.4 3 0 0 3 3 3 0 zf-RING of BARD1-type protein GFA PF04828.14 KXZ48570.1 - 6.4 7.2 10.9 1.5 9.2 0.3 3.4 4 1 0 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme Fasciclin PF02469.22 KXZ48571.1 - 3.6e-13 49.9 0.0 4.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 KXZ48572.1 - 1.5e-05 25.2 0.0 2.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Myticin-prepro PF10690.9 KXZ48572.1 - 0.11 12.7 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel MHB PF16525.5 KXZ48572.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Haemophore, haem-binding ABC1 PF03109.16 KXZ48574.1 - 2.3e-11 43.9 0.4 2.3e-11 43.9 0.4 1.6 2 1 0 2 2 2 1 ABC1 family Epimerase PF01370.21 KXZ48575.1 - 1.1e-20 74.2 0.0 4.1e-16 59.2 0.0 3.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXZ48575.1 - 3.5e-13 49.3 0.0 1.9e-06 27.3 0.0 3.0 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KXZ48575.1 - 2.1e-09 37.2 0.0 3.5e-06 26.6 0.0 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXZ48575.1 - 2.2e-09 37.5 0.0 2.7e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXZ48575.1 - 4.4e-08 32.5 0.0 2.5e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXZ48575.1 - 4.4e-05 22.7 0.0 0.23 10.5 0.0 2.5 1 1 1 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 KXZ48575.1 - 0.0033 16.9 1.4 1.6 8.2 0.0 2.5 3 0 0 3 3 3 2 short chain dehydrogenase NmrA PF05368.13 KXZ48575.1 - 0.0042 16.7 0.0 0.0097 15.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXZ48575.1 - 0.0051 16.0 0.1 1.2 8.3 0.0 2.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.10 KXZ48575.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 KR domain Fer2 PF00111.27 KXZ48576.1 - 3.3e-19 68.6 0.3 5e-19 68.0 0.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 2Fe-2S_Ferredox PF11591.8 KXZ48576.1 - 3.3e-11 42.8 17.3 5.2e-11 42.2 17.3 1.3 1 0 0 1 1 1 1 Ferredoxin chloroplastic transit peptide Fer2_4 PF13510.6 KXZ48576.1 - 0.0039 17.2 0.1 0.0075 16.3 0.1 1.7 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FeS PF04060.13 KXZ48576.1 - 0.25 11.0 3.3 0.57 9.9 0.3 2.7 3 0 0 3 3 3 0 Putative Fe-S cluster PIG-U PF06728.13 KXZ48577.1 - 2.7e-41 141.9 0.0 4.5e-27 95.1 0.0 2.2 2 0 0 2 2 2 2 GPI transamidase subunit PIG-U Acyl_transf_3 PF01757.22 KXZ48577.1 - 0.023 13.7 7.0 0.087 11.9 7.0 1.9 1 1 0 1 1 1 0 Acyltransferase family FAD_binding_3 PF01494.19 KXZ48578.1 - 2.4e-08 33.6 0.0 5.9e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXZ48578.1 - 0.0098 15.0 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase ArfGap PF01412.18 KXZ48579.1 - 1.1e-28 99.6 0.0 1.8e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_4 PF13637.6 KXZ48579.1 - 5.9e-13 49.0 0.2 2.4e-09 37.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48579.1 - 1.5e-08 34.7 1.6 0.0023 18.2 0.8 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48579.1 - 2.2e-06 27.8 6.8 0.0032 17.8 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KXZ48579.1 - 2.7e-06 27.9 1.0 1.3e-05 25.7 0.2 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48579.1 - 7.8e-06 25.9 4.3 0.2 12.3 0.1 4.4 3 1 0 3 3 3 2 Ankyrin repeat LCE PF14672.6 KXZ48579.1 - 0.0061 17.1 10.0 0.019 15.5 10.0 1.9 1 0 0 1 1 1 1 Late cornified envelope PIG-U PF06728.13 KXZ48580.1 - 7.9e-41 140.4 0.0 7.6e-27 94.3 0.0 2.2 2 0 0 2 2 2 2 GPI transamidase subunit PIG-U Acyl_transf_3 PF01757.22 KXZ48580.1 - 0.056 12.5 9.7 0.14 11.2 9.7 1.7 1 1 0 1 1 1 0 Acyltransferase family Pyr_redox_2 PF07992.14 KXZ48583.1 - 1.8e-61 207.9 0.1 2.4e-61 207.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXZ48583.1 - 1.1e-15 57.8 3.8 8.4e-15 55.0 0.7 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXZ48583.1 - 2.1e-15 57.0 4.5 5.4e-15 55.7 0.0 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ48583.1 - 4.9e-08 32.6 0.0 8.6e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ48583.1 - 0.00025 20.3 0.0 0.1 11.7 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Fer2 PF00111.27 KXZ48584.1 - 2.1e-18 66.0 0.4 3.2e-18 65.4 0.4 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 2Fe-2S_Ferredox PF11591.8 KXZ48584.1 - 3.5e-11 42.7 17.3 5.1e-11 42.2 17.3 1.2 1 0 0 1 1 1 1 Ferredoxin chloroplastic transit peptide DUF4428 PF14471.6 KXZ48584.1 - 0.0042 17.0 0.1 0.0067 16.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) AAA_12 PF13087.6 KXZ48586.1 - 2.1e-49 167.9 0.0 9.5e-49 165.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXZ48586.1 - 1.5e-30 106.9 0.3 1.3e-29 103.8 0.3 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ48586.1 - 7.8e-05 22.5 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KXZ48586.1 - 0.0024 17.6 0.4 0.14 12.0 0.0 3.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF1707 PF08044.11 KXZ48587.1 - 0.3 11.2 14.6 0.17 12.0 2.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_7 PF13499.6 KXZ48588.1 - 7e-28 96.9 0.0 7.8e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ48588.1 - 1.5e-25 86.8 1.9 9.4e-08 31.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KXZ48588.1 - 2.1e-21 74.0 1.3 1.4e-08 33.9 0.1 4.1 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KXZ48588.1 - 4.7e-18 64.8 0.4 1.1e-07 31.6 0.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KXZ48588.1 - 1.1e-16 60.9 0.0 1.6e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KXZ48588.1 - 8.9e-09 34.5 4.2 0.00013 21.3 0.1 3.9 4 0 0 4 4 4 2 EF hand GPHH PF16905.5 KXZ48588.1 - 0.00032 20.4 0.0 1.3 8.9 0.0 3.7 4 0 0 4 4 4 1 Voltage-dependent L-type calcium channel, IQ-associated SPARC_Ca_bdg PF10591.9 KXZ48588.1 - 0.0074 16.6 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dimerisation PF08100.11 KXZ48588.1 - 0.013 15.5 0.1 0.18 11.8 0.0 2.3 2 1 0 2 2 2 0 Dimerisation domain Moulting_cycle PF04870.16 KXZ48588.1 - 0.03 13.6 0.0 0.036 13.3 0.0 1.0 1 0 0 1 1 1 0 Moulting cycle UPF0154 PF03672.13 KXZ48588.1 - 0.08 13.0 0.0 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 KXZ48588.1 - 0.11 12.4 0.0 0.84 9.5 0.0 2.3 1 1 0 1 1 1 0 Caleosin related protein DUF3349 PF11829.8 KXZ48588.1 - 0.12 13.2 0.1 2 9.2 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) zf-MYND PF01753.18 KXZ48590.1 - 0.059 13.5 5.5 0.11 12.7 5.5 1.4 1 0 0 1 1 1 0 MYND finger Fasciclin PF02469.22 KXZ48591.1 - 2.7e-20 72.9 0.0 0.001 19.3 0.0 5.6 5 0 0 5 5 5 5 Fasciclin domain Glycos_transf_2 PF00535.26 KXZ48592.1 - 1.1e-32 113.1 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXZ48592.1 - 6.6e-16 58.9 0.0 8.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXZ48592.1 - 0.00015 21.3 0.0 0.00054 19.5 0.0 1.7 1 1 0 2 2 2 1 Glycosyl transferase family 21 PIN_10 PF18478.1 KXZ48592.1 - 0.0046 17.1 0.0 0.0092 16.2 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Glyco_tranf_2_2 PF10111.9 KXZ48592.1 - 0.0075 15.8 0.0 0.0095 15.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KXZ48592.1 - 0.042 14.4 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF459 PF04311.13 KXZ48592.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) AMPK1_CBM PF16561.5 KXZ48593.1 - 2.2e-12 47.0 0.0 4.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DSPc PF00782.20 KXZ48593.1 - 2.1e-11 43.8 0.0 3.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXZ48593.1 - 0.099 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KXZ48593.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Abhydrolase_6 PF12697.7 KXZ48594.1 - 1.1e-22 81.7 2.1 1.3e-22 81.5 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ48594.1 - 8.8e-18 64.9 0.1 1.3e-10 41.4 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ48594.1 - 2.7e-14 53.0 0.0 4.4e-14 52.3 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 KXZ48594.1 - 5.7e-05 23.1 0.0 0.94 9.4 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.10 KXZ48594.1 - 0.0003 20.9 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 KXZ48594.1 - 0.00043 20.1 0.0 0.86 9.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.20 KXZ48594.1 - 0.0018 18.0 0.1 0.0045 16.7 0.1 1.6 1 0 0 1 1 1 1 Putative esterase DUF3089 PF11288.8 KXZ48594.1 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) BAAT_C PF08840.11 KXZ48594.1 - 0.032 14.2 0.0 0.089 12.7 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 KXZ48594.1 - 0.05 13.7 0.1 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain zf-CCHC PF00098.23 KXZ48595.1 - 3.3e-07 30.1 1.0 4.8e-07 29.5 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXZ48595.1 - 0.0029 17.4 1.2 0.0041 16.9 1.2 1.2 1 0 0 1 1 1 1 Zinc knuckle ZapB PF06005.12 KXZ48595.1 - 0.019 15.4 2.1 0.037 14.5 2.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB zf-CCHC_5 PF14787.6 KXZ48595.1 - 0.028 14.1 2.0 0.028 14.1 2.0 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KXZ48595.1 - 0.054 13.5 1.0 0.1 12.6 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle YabA PF06156.13 KXZ48595.1 - 0.18 12.5 0.1 0.31 11.7 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Lipase_3 PF01764.25 KXZ48596.1 - 1.3e-09 38.0 0.2 3.2e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXZ48596.1 - 0.003 18.2 6.6 0.0031 18.1 4.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ48596.1 - 0.086 12.5 0.4 0.31 10.6 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ48596.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF5319 PF17252.2 KXZ48596.1 - 1.3 9.3 2.7 27 5.0 0.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5319) Sporozoite_P67 PF05642.11 KXZ48596.1 - 3.2 5.7 9.9 4.8 5.1 9.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 KXZ48596.1 - 9.4 4.2 12.2 13 3.8 12.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pkinase PF00069.25 KXZ48597.1 - 2.3e-25 89.4 0.0 2.9e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48597.1 - 4.1e-24 85.3 0.0 2.8e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase TetR_C_20 PF17925.1 KXZ48597.1 - 0.0078 16.5 1.6 0.089 13.1 0.1 2.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Pkinase_fungal PF17667.1 KXZ48597.1 - 0.075 11.8 0.0 2 7.1 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Methyltransf_22 PF13383.6 KXZ48598.1 - 6.6e-15 55.4 0.0 3.1e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KXZ48598.1 - 4.7e-08 33.2 0.0 5.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF212 PF02681.14 KXZ48601.1 - 1.5e-32 112.4 1.7 1.9e-32 112.0 1.7 1.1 1 0 0 1 1 1 1 Divergent PAP2 family PAP2 PF01569.21 KXZ48601.1 - 0.056 13.2 4.0 2 8.2 0.1 2.2 2 0 0 2 2 2 0 PAP2 superfamily DUF3482 PF11981.8 KXZ48601.1 - 4.2 6.7 12.9 7.2 5.9 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Patatin PF01734.22 KXZ48604.1 - 9.8e-09 35.7 1.6 1.2e-06 28.9 1.6 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Lactamase_B_2 PF12706.7 KXZ48605.1 - 0.00082 18.9 0.1 0.0015 18.1 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF4995 PF16386.5 KXZ48605.1 - 0.19 11.8 0.2 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function Acetyltransf_1 PF00583.25 KXZ48606.1 - 3.3e-14 53.1 0.0 5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ48606.1 - 1.9e-08 34.3 0.0 5.1e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ48606.1 - 2.5e-07 31.0 0.1 4.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ48606.1 - 9.3e-06 25.5 0.0 5.1e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 KXZ48606.1 - 0.0029 17.8 0.0 0.0036 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ48606.1 - 0.012 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_17 PF17668.1 KXZ48606.1 - 0.029 15.2 0.2 0.055 14.3 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SF3A2 PF16835.5 KXZ48607.1 - 1.5e-36 124.7 0.1 2.1e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KXZ48607.1 - 2e-06 28.0 0.6 3.6e-06 27.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KXZ48607.1 - 1.2e-05 25.3 0.6 1.8e-05 24.6 0.6 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein CBFD_NFYB_HMF PF00808.23 KXZ48608.1 - 1.1e-16 60.8 0.2 1.6e-16 60.3 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ48608.1 - 0.00013 22.3 0.1 0.0002 21.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KXZ48608.1 - 0.044 13.8 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Herpes_UL35 PF04496.12 KXZ48608.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL35 family DUF4436 PF14494.6 KXZ48610.1 - 6.6e-21 74.8 0.3 8.7e-21 74.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) ADH_N PF08240.12 KXZ48611.1 - 2.7e-23 81.9 5.5 2.7e-23 81.9 5.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXZ48611.1 - 1e-20 74.0 0.0 1.8e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXZ48611.1 - 3.7e-06 26.6 0.2 0.001 18.6 0.6 2.6 2 1 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXZ48611.1 - 0.00011 21.6 1.7 0.00019 20.8 1.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXZ48611.1 - 0.0019 19.2 0.0 0.0039 18.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KXZ48611.1 - 0.05 14.3 0.1 0.11 13.2 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.28 KXZ48613.1 - 2.9e-11 44.2 1.2 4.3e-11 43.7 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EAF PF09816.9 KXZ48614.1 - 2e-08 34.5 0.0 3.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF89 PF01937.19 KXZ48615.1 - 3.9e-71 239.9 0.0 1.3e-70 238.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF89 BAR_3 PF16746.5 KXZ48616.1 - 1.9e-14 54.0 0.0 3e-10 40.2 0.0 2.0 1 1 1 2 2 2 2 BAR domain of APPL family ArfGap PF01412.18 KXZ48617.1 - 1.1e-31 109.3 0.0 1.8e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_4 PF13637.6 KXZ48617.1 - 3.5e-11 43.4 0.1 7.8e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48617.1 - 3.6e-11 43.1 0.9 2.9e-08 33.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48617.1 - 1.4e-09 38.4 0.1 3.2e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ48617.1 - 5.1e-09 36.2 2.0 0.00074 19.9 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXZ48617.1 - 2.2e-08 33.7 2.1 0.0037 17.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat FAD_binding_3 PF01494.19 KXZ48618.1 - 9.3e-14 51.4 0.0 2e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KXZ48618.1 - 9.9e-05 21.5 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Denso_VP4 PF02336.15 KXZ48618.1 - 0.3 10.0 0.2 0.43 9.4 0.2 1.1 1 0 0 1 1 1 0 Capsid protein VP4 DPBB_1 PF03330.18 KXZ48619.1 - 1.6e-06 28.3 0.0 5.9e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 Lytic transglycolase Peptidase_C13 PF01650.18 KXZ48620.1 - 2.6e-25 89.4 0.0 3.1e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family SnoaL_2 PF12680.7 KXZ48621.1 - 5.6e-08 33.3 0.1 1.7e-07 31.8 0.1 1.9 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXZ48621.1 - 0.0051 16.6 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 KXZ48621.1 - 0.029 14.7 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 KXZ48621.1 - 0.14 12.5 0.2 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Abhydrolase_1 PF00561.20 KXZ48623.1 - 0.00027 20.7 0.2 0.00071 19.3 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Acyl_transf_1 PF00698.21 KXZ48623.1 - 0.0041 16.7 6.6 0.19 11.2 1.3 2.4 2 0 0 2 2 2 2 Acyl transferase domain DUF5644 PF18712.1 KXZ48623.1 - 0.29 11.2 0.0 0.48 10.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5644) Gluconate_2-dh3 PF13618.6 KXZ48625.1 - 0.11 12.7 0.3 9.3 6.5 0.1 2.0 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 CENP-N PF05238.13 KXZ48625.1 - 0.19 11.0 0.2 5.9 6.1 0.0 1.9 2 0 0 2 2 2 0 Kinetochore protein CHL4 like MFS_1 PF07690.16 KXZ48627.1 - 1.5e-07 30.7 54.2 0.00013 21.0 18.7 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF5325 PF17259.2 KXZ48627.1 - 0.047 13.6 0.3 0.2 11.5 0.3 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5325) COX2_TM PF02790.15 KXZ48628.1 - 1.3e-23 82.9 6.8 2.3e-23 82.1 6.8 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain COX2 PF00116.20 KXZ48628.1 - 0.00034 20.5 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain DUF4234 PF14018.6 KXZ48628.1 - 0.093 12.9 2.1 0.18 12.0 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) LRR_6 PF13516.6 KXZ48629.1 - 7.2e-15 53.7 6.3 2e-05 24.3 0.3 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KXZ48629.1 - 2.9e-06 27.5 1.4 0.0038 17.6 0.0 2.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ48629.1 - 0.00042 20.0 3.4 0.045 13.5 0.1 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KXZ48629.1 - 0.0031 17.9 0.2 0.84 10.4 0.0 3.6 3 1 0 3 3 3 1 Leucine Rich Repeat Med25_NR-box PF11244.8 KXZ48629.1 - 0.025 15.0 0.1 0.059 13.8 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing Aminotran_5 PF00266.19 KXZ48630.1 - 1.6e-19 70.2 0.0 9.8e-14 51.1 0.0 2.9 2 1 1 3 3 3 2 Aminotransferase class-V MOSC_N PF03476.16 KXZ48630.1 - 2.9e-19 69.1 0.0 7.6e-18 64.5 0.0 2.8 3 0 0 3 3 3 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KXZ48630.1 - 2e-16 60.2 0.0 5.7e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 MOSC domain Oxidored_q4 PF00507.19 KXZ48631.1 - 1.6e-29 101.9 4.8 2.3e-29 101.5 4.8 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Pkinase_Tyr PF07714.17 KXZ48633.1 - 1.1e-39 136.3 0.0 8.9e-32 110.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ48633.1 - 2.6e-38 131.9 0.0 5e-38 131.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ48633.1 - 0.00036 20.5 0.7 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ48633.1 - 0.0081 15.0 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ48633.1 - 0.051 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRIMA1 PF16101.5 KXZ48633.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF1264 PF06884.11 KXZ48634.1 - 3.6e-43 147.1 3.0 1.6e-34 119.0 1.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1264) Fringe PF02434.16 KXZ48635.1 - 0.00033 20.2 0.5 0.31 10.5 0.2 2.3 2 0 0 2 2 2 2 Fringe-like LSM PF01423.22 KXZ48636.1 - 3.3e-15 55.5 0.0 6.4e-15 54.6 0.0 1.4 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXZ48636.1 - 0.0058 16.7 0.0 0.0061 16.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3456 PF11938.8 KXZ48637.1 - 0.083 13.4 9.3 0.11 13.0 0.7 2.8 2 2 0 3 3 3 0 TLR4 regulator and MIR-interacting MSAP CD99L2 PF12301.8 KXZ48637.1 - 0.19 12.0 6.9 0.043 14.1 1.4 2.1 2 0 0 2 2 2 0 CD99 antigen like protein 2 Methyltransf_16 PF10294.9 KXZ48638.1 - 1.9e-21 76.6 0.0 2.4e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXZ48638.1 - 0.025 14.0 0.1 0.033 13.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) D-ser_dehydrat PF14031.6 KXZ48640.1 - 7e-24 84.3 0.3 4.1e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXZ48640.1 - 4.2e-19 69.1 0.4 5.3e-19 68.7 0.4 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Transglut_core PF01841.19 KXZ48640.1 - 0.071 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Myb_DNA-bind_4 PF13837.6 KXZ48641.1 - 9.5e-07 29.1 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KXZ48641.1 - 0.14 13.2 0.0 0.28 12.2 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain SET PF00856.28 KXZ48643.1 - 0.03 14.7 0.0 0.24 11.8 0.0 2.3 1 1 0 1 1 1 0 SET domain WD40 PF00400.32 KXZ48644.1 - 1e-21 76.8 11.9 0.00047 20.9 0.1 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat NACHT PF05729.12 KXZ48644.1 - 8.7e-07 29.0 0.0 5.8e-05 23.1 0.0 2.8 3 0 0 3 3 3 1 NACHT domain ANAPC4_WD40 PF12894.7 KXZ48644.1 - 1.1e-06 28.8 0.0 0.63 10.4 0.0 4.7 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KXZ48644.1 - 0.021 15.1 0.1 0.064 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ge1_WD40 PF16529.5 KXZ48644.1 - 0.097 11.6 0.1 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KXZ48644.1 - 0.28 11.5 4.6 0.29 11.5 1.5 2.6 2 1 0 2 2 2 0 AAA ATPase domain PP2C PF00481.21 KXZ48645.1 - 8.4e-08 32.2 0.0 8.6e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.32 KXZ48646.1 - 4e-17 62.3 4.9 0.0099 16.7 0.1 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ48646.1 - 0.0093 16.2 0.0 5 7.5 0.0 3.0 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ48646.1 - 0.13 11.2 0.4 5.8 5.8 0.0 3.0 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KXZ48647.1 - 5.3e-12 46.1 3.0 4.2e-05 24.2 0.2 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat DNA_pol_A_exo1 PF01612.20 KXZ48648.1 - 2e-14 53.7 0.0 8.4e-12 45.1 0.0 2.4 2 1 0 2 2 2 2 3'-5' exonuclease FHA PF00498.26 KXZ48649.1 - 7.8e-19 67.8 0.0 6.7e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KXZ48649.1 - 4.1e-07 30.2 0.0 6.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Abhydrolase_1 PF00561.20 KXZ48650.1 - 2.1e-21 76.7 0.0 5e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ48650.1 - 1.6e-16 60.3 0.0 4.1e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ48650.1 - 2.2e-13 51.3 12.6 2.8e-13 51.0 12.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXZ48650.1 - 0.0003 20.4 0.0 0.8 9.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF900 PF05990.12 KXZ48650.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Palm_thioest PF02089.15 KXZ48650.1 - 0.0058 16.5 0.0 0.0083 16.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KXZ48650.1 - 0.01 15.5 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 KXZ48650.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KXZ48650.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_2 PF01674.18 KXZ48650.1 - 0.14 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Lipase (class 2) DUF676 PF05057.14 KXZ48650.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 KXZ48650.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 KXZ48650.1 - 0.23 11.1 0.0 3.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Pkinase PF00069.25 KXZ48653.1 - 1.1e-33 116.7 0.0 1.6e-26 93.3 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48653.1 - 1.1e-31 110.0 0.0 3e-25 89.0 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 KXZ48653.1 - 0.0037 16.7 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ48653.1 - 0.042 13.8 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_Ag35 PF03286.14 KXZ48655.1 - 0.046 13.5 1.6 0.073 12.9 1.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HEAT_2 PF13646.6 KXZ48655.1 - 9.9 6.6 7.9 5.5 7.4 0.3 2.7 2 0 0 2 2 2 0 HEAT repeats zf-MYND PF01753.18 KXZ48656.1 - 2e-09 37.4 14.7 3.6e-09 36.5 14.7 1.5 1 0 0 1 1 1 1 MYND finger RhlB PF12300.8 KXZ48656.1 - 0.024 14.8 13.8 0.041 14.0 13.8 1.4 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB zf-C6H2 PF15801.5 KXZ48656.1 - 0.29 11.5 9.2 0.72 10.2 9.2 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TGT PF01702.18 KXZ48657.1 - 8.1e-65 219.3 0.0 1.2e-64 218.7 0.0 1.3 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ank_4 PF13637.6 KXZ48659.1 - 1.6e-13 50.9 2.8 0.0012 19.4 1.4 7.1 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48659.1 - 8.1e-12 45.6 0.0 0.0042 17.6 0.4 4.9 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48659.1 - 1.6e-10 40.3 1.9 14 6.7 0.1 9.0 10 0 0 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 KXZ48659.1 - 5.4e-07 29.8 8.3 3.6 8.0 0.5 7.8 5 2 3 8 8 8 2 Ankyrin repeats (many copies) RRXRR PF14239.6 KXZ48660.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 RRXRR protein Ribosomal_60s PF00428.19 KXZ48660.1 - 5.8 7.6 14.0 0.45 11.1 6.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C3HC4_3 PF13920.6 KXZ48661.1 - 3.1e-07 30.1 10.1 3.8e-07 29.9 10.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Paired_CXXCH_1 PF09699.10 KXZ48661.1 - 0.034 13.9 10.2 0.13 12.1 0.1 3.0 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) LRR19-TM PF15176.6 KXZ48661.1 - 0.063 13.3 0.2 0.079 13.0 0.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain FAM176 PF14851.6 KXZ48661.1 - 0.12 12.0 1.1 0.14 11.8 1.1 1.1 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 KXZ48661.1 - 0.6 10.3 11.0 0.73 10.0 11.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_2 PF13639.6 KXZ48661.1 - 0.73 10.2 11.6 1.2 9.6 11.6 1.3 1 0 0 1 1 1 0 Ring finger domain CDC45 PF02724.14 KXZ48661.1 - 0.77 8.0 3.8 0.89 7.8 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 KXZ48661.1 - 0.83 10.1 13.0 1.4 9.4 13.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_5 PF14634.6 KXZ48661.1 - 1 9.4 12.4 1.5 8.8 12.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DUF2457 PF10446.9 KXZ48661.1 - 1.5 7.9 10.8 1.6 7.8 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MoeA_N PF03453.17 KXZ48662.1 - 1e-41 142.3 6.8 1.5e-41 141.8 4.4 2.1 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KXZ48662.1 - 3.9e-24 85.0 0.0 7e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KXZ48662.1 - 1.2e-13 51.0 1.7 8.3e-09 35.5 0.1 3.1 3 0 0 3 3 3 2 MoeA C-terminal region (domain IV) E1-E2_ATPase PF00122.20 KXZ48663.1 - 1.9e-49 167.7 1.4 1.9e-49 167.7 1.4 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXZ48663.1 - 3.1e-14 53.8 0.9 1.1e-13 51.9 0.9 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXZ48663.1 - 9.9e-14 50.8 0.0 1.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXZ48663.1 - 0.00022 21.0 0.4 0.0085 15.9 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ48663.1 - 0.0019 18.2 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 KXZ48663.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CAF1 PF04857.20 KXZ48667.1 - 1.9e-18 66.7 1.3 6.2e-08 32.2 0.0 2.7 1 1 1 2 2 2 2 CAF1 family ribonuclease RAMA PF18755.1 KXZ48669.1 - 2.8e-06 27.7 0.0 7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated RAMA PF18755.1 KXZ48670.1 - 6.8e-10 39.3 0.0 9.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated zf-RING_UBOX PF13445.6 KXZ48672.1 - 3.2e-08 33.5 5.7 6.3e-08 32.5 5.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ48672.1 - 9.4e-08 31.8 6.9 1.7e-07 30.9 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ48672.1 - 2.7e-05 24.0 7.3 4.9e-05 23.1 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.11 KXZ48672.1 - 9.4e-05 22.7 15.7 9.4e-05 22.7 15.7 6.8 2 1 4 6 6 3 1 Autophagy protein 16 (ATG16) zf-C3HC4_4 PF15227.6 KXZ48672.1 - 0.00011 22.2 7.6 0.00022 21.3 7.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXZ48672.1 - 0.00056 19.8 6.2 0.00098 19.0 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXZ48672.1 - 0.0046 17.3 8.7 0.0078 16.5 8.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXZ48672.1 - 0.0072 16.2 8.6 0.012 15.4 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ48672.1 - 0.018 14.9 6.7 0.035 14.0 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KXZ48672.1 - 0.039 13.8 5.5 0.076 12.9 5.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_PEP_C PF04513.12 KXZ48672.1 - 0.12 12.4 15.9 5.2 7.1 0.4 5.5 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RING_11 PF17123.5 KXZ48672.1 - 0.35 10.7 4.1 0.66 9.8 4.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger ZapB PF06005.12 KXZ48672.1 - 0.44 11.0 0.1 0.44 11.0 0.1 8.3 5 2 1 7 7 5 0 Cell division protein ZapB DUF1664 PF07889.12 KXZ48672.1 - 0.69 10.0 20.0 0.73 9.9 0.1 6.2 3 2 4 7 7 7 0 Protein of unknown function (DUF1664) zf-RING_10 PF16685.5 KXZ48672.1 - 3.1 8.0 7.5 5.7 7.2 7.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Fib_alpha PF08702.10 KXZ48672.1 - 4.8 7.4 15.4 4.5 7.4 0.1 4.6 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family zf-MIZ PF02891.20 KXZ48673.1 - 0.0034 17.1 0.1 0.0083 15.9 0.1 1.7 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger TFIIA PF03153.13 KXZ48673.1 - 0.056 13.4 11.3 0.066 13.2 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 KXZ48673.1 - 1.3 9.7 13.4 2.3 8.9 13.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TT_ORF2 PF02957.15 KXZ48673.1 - 2.4 9.1 7.0 5.9 7.8 0.1 2.5 2 0 0 2 2 2 0 TT viral ORF2 Suf PF05843.14 KXZ48673.1 - 6.1 6.7 6.3 8.3 6.3 6.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) COX6C PF02937.15 KXZ48674.1 - 0.016 15.4 0.2 0.12 12.5 0.0 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIc DUF5320 PF17253.2 KXZ48674.1 - 0.067 14.3 0.1 0.078 14.1 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Thioredoxin PF00085.20 KXZ48675.1 - 7.2e-16 58.1 0.1 1.2e-15 57.3 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXZ48675.1 - 0.00072 19.8 0.1 0.00099 19.4 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 KXZ48675.1 - 0.019 13.9 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosducin OST3_OST6 PF04756.13 KXZ48675.1 - 0.032 13.6 0.1 0.04 13.3 0.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXZ48675.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 KXZ48675.1 - 0.13 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Myc-LZ PF02344.15 KXZ48676.1 - 0.042 14.0 0.3 0.042 14.0 0.3 3.4 4 0 0 4 4 4 0 Myc leucine zipper domain Fib_alpha PF08702.10 KXZ48676.1 - 0.11 12.6 0.0 0.11 12.6 0.0 6.0 3 2 5 8 8 8 0 Fibrinogen alpha/beta chain family Shugoshin_N PF07558.11 KXZ48676.1 - 0.24 11.3 3.2 4.5 7.2 0.1 3.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF4988 PF16378.5 KXZ48676.1 - 0.32 10.6 1.1 1.5 8.5 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function fn3_PAP PF17808.1 KXZ48677.1 - 2.2e-17 63.3 0.1 1.6e-16 60.5 0.1 2.1 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Pur_ac_phosph_N PF16656.5 KXZ48677.1 - 4.4e-16 59.2 0.0 1.2e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KXZ48677.1 - 2.5e-10 41.2 0.5 4.6e-10 40.3 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KXZ48677.1 - 6.1e-08 33.4 0.0 2.1e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C TPR_2 PF07719.17 KXZ48678.1 - 0.0035 17.3 1.5 0.0035 17.3 1.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Arm PF00514.23 KXZ48678.1 - 0.0044 17.0 0.5 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat TPR_1 PF00515.28 KXZ48678.1 - 0.0076 16.0 0.7 0.0076 16.0 0.7 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ48678.1 - 0.0076 15.9 1.0 0.0076 15.9 1.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 KXZ48678.1 - 0.0099 16.5 2.4 0.0099 16.5 2.4 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ48678.1 - 0.022 15.0 0.3 0.022 15.0 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KXZ48678.1 - 0.2 11.8 1.2 0.46 10.6 1.2 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KXZ48678.1 - 0.2 11.9 3.4 9.3 6.7 0.2 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ48678.1 - 1.4 9.2 10.0 16 5.8 4.4 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 KXZ48679.1 - 1.2e-68 231.6 0.1 1.6e-68 231.3 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PKHD_C PF18331.1 KXZ48679.1 - 0.031 14.3 0.0 6.8 6.8 0.0 2.5 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain AIRS PF00586.24 KXZ48679.1 - 0.18 12.5 1.1 1.2 9.9 0.1 2.6 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain cNMP_binding PF00027.29 KXZ48680.1 - 1.9e-05 24.6 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KXZ48680.1 - 0.00098 18.4 2.6 0.0027 17.0 2.6 1.7 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXZ48680.1 - 0.0022 17.9 1.8 0.0077 16.2 1.8 2.0 1 1 0 1 1 1 1 Ion channel BACK PF07707.15 KXZ48681.1 - 6.3e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch EF-hand_1 PF00036.32 KXZ48683.1 - 0.0044 16.5 0.0 0.0094 15.4 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ48683.1 - 0.024 14.6 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KXZ48683.1 - 0.043 13.3 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KXZ48683.1 - 0.053 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair RicinB_lectin_2 PF14200.6 KXZ48684.1 - 1.2e-48 163.7 24.5 1.7e-19 70.3 0.2 4.5 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ48684.1 - 1e-34 119.5 11.4 3e-17 63.1 0.2 2.5 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ48684.1 - 2.6e-32 112.3 6.3 2.6e-32 112.3 6.3 2.6 3 1 0 3 3 3 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ48684.1 - 6.5e-11 42.0 6.9 5.8e-05 22.7 0.8 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain Herpes_UL52 PF03121.15 KXZ48684.1 - 0.013 15.4 0.1 0.15 12.1 0.0 2.7 2 1 1 3 3 3 0 Herpesviridae UL52/UL70 DNA primase SpoIIE PF07228.12 KXZ48688.1 - 1.5e-08 34.8 0.1 3.8e-07 30.2 0.0 2.9 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXZ48688.1 - 0.00015 21.5 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PI3K_1B_p101 PF10486.9 KXZ48688.1 - 0.25 9.1 11.8 0.36 8.5 11.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Methyltransf_25 PF13649.6 KXZ48689.1 - 4.1e-07 30.6 0.1 6.8e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ48689.1 - 9.4e-06 26.2 0.1 1.5e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ48689.1 - 0.00034 20.4 0.0 0.00051 19.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXZ48689.1 - 0.0033 16.8 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXZ48689.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXZ48689.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 KXZ48689.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 KXZ48689.1 - 0.038 14.7 0.1 0.057 14.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 KXZ48689.1 - 0.073 13.4 0.1 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase KRAP_IP3R_bind PF14722.6 KXZ48689.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain RRM_1 PF00076.22 KXZ48690.1 - 5.4e-16 58.2 0.0 1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KXZ48690.1 - 2.9e-14 52.8 0.1 5.9e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KXZ48690.1 - 0.00012 22.9 0.1 0.00035 21.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 KXZ48690.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif CTK3 PF12243.8 KXZ48690.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Peptidase_S77 PF03420.13 KXZ48692.1 - 7.6e-11 42.0 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Prohead core protein serine protease FUSC_2 PF13515.6 KXZ48693.1 - 2.3e-10 40.7 10.9 6.7e-10 39.2 10.9 1.8 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ALMT PF11744.8 KXZ48693.1 - 4.4e-08 32.4 2.9 6.9e-08 31.8 2.9 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter Exostosin PF03016.15 KXZ48695.1 - 8.6e-25 87.6 0.0 2.5e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 Exostosin family EGF_Tenascin PF18720.1 KXZ48695.1 - 0.00028 20.8 12.0 0.00028 20.8 12.0 2.3 2 0 0 2 2 2 1 Tenascin EGF domain EGF_2 PF07974.13 KXZ48695.1 - 0.0067 16.8 16.6 0.0067 16.8 16.6 3.1 4 0 0 4 4 4 1 EGF-like domain Cpn60_TCP1 PF00118.24 KXZ48696.1 - 3.4e-153 510.8 2.1 3.9e-153 510.6 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TPR_12 PF13424.6 KXZ48697.1 - 4.1e-56 187.2 48.5 5.8e-17 61.8 6.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ48697.1 - 3.9e-50 166.4 52.2 2.4e-10 39.9 0.1 10.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ48697.1 - 6.7e-14 52.0 25.5 2e-08 34.0 7.3 3.8 2 1 1 3 3 3 3 MalT-like TPR region TPR_1 PF00515.28 KXZ48697.1 - 8e-13 47.6 19.8 1.2e-06 28.0 0.2 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ48697.1 - 2.1e-10 39.9 35.2 1.7e-05 24.6 0.4 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ48697.1 - 2e-09 36.8 27.7 0.00053 19.8 0.1 8.2 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ48697.1 - 2.1e-07 30.6 15.2 0.0036 17.4 0.2 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ48697.1 - 5.7e-05 23.7 21.1 0.00079 20.0 5.3 10.7 7 2 3 10 10 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ48697.1 - 0.017 15.9 74.9 0.043 14.6 1.3 11.9 11 2 2 13 13 11 0 Tetratricopeptide repeat DUF4054 PF13262.6 KXZ48697.1 - 0.078 13.0 0.2 0.078 13.0 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4054) ANAPC3 PF12895.7 KXZ48697.1 - 0.52 10.6 2.7 3.5 7.9 0.1 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXZ48697.1 - 1.2 9.6 9.9 7.6 7.2 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 KXZ48697.1 - 1.8 9.0 3.7 3.7 8.0 0.1 3.1 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.7 KXZ48697.1 - 8.6 6.2 7.4 2.4 8.0 0.3 3.4 4 0 0 4 4 4 0 PPR repeat Chloroa_b-bind PF00504.21 KXZ48699.1 - 1.9e-52 178.1 0.1 2.3e-52 177.8 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Putative_PNPOx PF01243.20 KXZ48699.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Cyt_b-c1_8 PF10890.8 KXZ48700.1 - 1.1e-21 76.9 0.0 1.3e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 UcrQ PF02939.16 KXZ48700.1 - 6e-05 22.9 0.0 7.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 UcrQ family Methyltransf_11 PF08241.12 KXZ48701.1 - 7.1e-17 61.8 0.0 1.7e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ48701.1 - 8.1e-12 45.7 0.0 2.7e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ48701.1 - 4.8e-08 33.6 0.0 7.6e-07 29.8 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ48701.1 - 0.00013 21.8 0.0 0.00035 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ48701.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KXZ48701.1 - 0.021 15.8 0.0 0.046 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DEP PF00610.21 KXZ48705.1 - 6.4e-18 64.6 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3618 PF12277.8 KXZ48705.1 - 0.33 11.3 5.4 0.98 9.7 5.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF2470 PF10615.9 KXZ48706.1 - 3.6e-05 24.3 0.0 7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyrid_oxidase_2 PF13883.6 KXZ48706.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KXZ48706.1 - 0.098 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase GHMP_kinases_N PF00288.26 KXZ48707.1 - 2.4e-07 30.9 0.2 2.4e-07 30.9 0.2 2.4 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXZ48707.1 - 2.6e-05 24.5 1.0 2.6e-05 24.5 1.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal Ank_4 PF13637.6 KXZ48708.1 - 2.5e-09 37.5 1.2 0.49 11.0 0.0 6.3 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48708.1 - 1.7e-08 34.9 0.0 0.19 12.3 0.0 4.6 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48708.1 - 9.2e-06 25.6 1.9 74 4.4 0.0 7.5 8 0 0 8 8 8 0 Ankyrin repeat Ad_Cy_reg PF16701.5 KXZ48708.1 - 0.006 16.4 0.2 0.26 11.0 0.0 3.3 3 1 0 4 4 4 1 Adenylate cyclase regulatory domain HTH_39 PF14090.6 KXZ48708.1 - 0.093 12.5 0.0 0.4 10.5 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain Ovate PF04844.13 KXZ48711.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Transcriptional repressor, ovate SNF2_N PF00176.23 KXZ48712.1 - 9.4e-47 159.4 0.0 1.4e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KXZ48712.1 - 6.2e-10 38.8 0.3 3.4e-09 36.5 0.2 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KXZ48712.1 - 0.0069 16.4 0.0 0.034 14.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1835 PF08874.10 KXZ48712.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Radical_SAM PF04055.21 KXZ48715.1 - 4.3e-10 40.2 0.0 1.1e-09 38.9 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KXZ48715.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KXZ48715.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Epimerase PF01370.21 KXZ48717.1 - 4.3e-48 163.9 0.0 1.4e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ48717.1 - 1e-24 87.6 0.0 2.1e-14 53.7 0.0 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXZ48717.1 - 9.9e-08 31.3 0.0 2.6e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXZ48717.1 - 1.3e-06 28.4 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXZ48717.1 - 2.7e-05 23.5 0.0 0.0049 16.1 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXZ48717.1 - 0.00029 20.1 0.0 0.024 13.8 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KXZ48717.1 - 0.0035 16.5 0.0 0.096 11.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KXZ48717.1 - 0.025 14.0 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 KXZ48717.1 - 0.15 11.6 0.1 1.2 8.6 0.1 2.1 1 1 0 1 1 1 0 NmrA-like family Nop52 PF05997.12 KXZ48718.1 - 2.5e-38 132.1 0.0 8.9e-29 100.8 0.0 2.2 1 1 1 2 2 2 2 Nucleolar protein,Nop52 DS PF01916.17 KXZ48719.1 - 8.3e-127 422.4 0.0 9.6e-127 422.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase GGACT PF06094.12 KXZ48720.1 - 2.4e-25 89.5 0.7 2.7e-25 89.3 0.7 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like BACK PF07707.15 KXZ48722.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch 2-Hacid_dh_C PF02826.19 KXZ48723.1 - 6.2e-44 149.5 0.0 7.8e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXZ48723.1 - 0.002 18.6 0.1 0.0045 17.5 0.0 1.6 2 0 0 2 2 2 1 XdhC Rossmann domain Rossmann-like PF10727.9 KXZ48723.1 - 0.0079 16.1 1.4 0.013 15.4 1.1 1.5 1 1 0 1 1 1 1 Rossmann-like domain Oxidored_nitro PF00148.19 KXZ48723.1 - 0.02 13.6 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ADH_zinc_N PF00107.26 KXZ48723.1 - 0.037 14.0 0.2 0.052 13.5 0.2 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 KXZ48723.1 - 0.15 12.6 0.2 0.26 11.9 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GCP_N_terminal PF17681.1 KXZ48724.1 - 6.3e-19 68.7 0.0 7.1e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXZ48725.1 - 1.2e-40 139.9 0.0 1.5e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal ATP-synt_A PF00119.20 KXZ48726.1 - 5.2e-33 114.8 10.6 7.3e-33 114.3 10.6 1.2 1 0 0 1 1 1 1 ATP synthase A chain Doppel PF11466.8 KXZ48726.1 - 0.031 13.9 0.4 0.031 13.9 0.4 2.2 2 0 0 2 2 2 0 Prion-like protein Doppel PPP1R26_N PF15740.5 KXZ48727.1 - 0.32 9.6 1.0 0.43 9.2 1.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 26 N-terminus IBR PF01485.21 KXZ48729.1 - 6.1e-19 68.0 43.0 1.1e-10 41.5 5.4 5.3 4 1 1 5 5 5 4 IBR domain, a half RING-finger domain RWD PF05773.22 KXZ48729.1 - 2.4e-07 31.0 0.0 1.3e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 RWD domain zf-RING_2 PF13639.6 KXZ48729.1 - 0.00016 22.0 7.7 0.00016 22.0 7.7 5.1 4 1 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KXZ48729.1 - 0.0015 18.5 7.5 0.0015 18.5 7.5 4.8 5 0 0 5 5 5 2 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ48729.1 - 0.0017 18.2 4.2 0.0017 18.2 4.2 5.5 4 3 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ48729.1 - 0.0043 17.1 6.3 0.0043 17.1 6.3 3.7 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ48729.1 - 0.0076 16.1 4.7 0.0076 16.1 4.7 5.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Exo_endo_phos PF03372.23 KXZ48730.1 - 3.4e-11 43.1 2.7 1.4e-10 41.1 2.7 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IBR PF01485.21 KXZ48731.1 - 3.3e-20 72.1 52.0 8.6e-12 45.1 6.1 5.2 4 1 1 5 5 5 4 IBR domain, a half RING-finger domain RWD PF05773.22 KXZ48731.1 - 6.5e-07 29.7 0.0 1.3e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 RWD domain zf-RING_2 PF13639.6 KXZ48731.1 - 0.00013 22.2 7.7 0.00013 22.2 7.7 4.4 4 0 0 4 4 4 2 Ring finger domain zf-RING_5 PF14634.6 KXZ48731.1 - 0.0012 18.8 7.5 0.0012 18.8 7.5 4.8 4 1 1 5 5 5 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ48731.1 - 0.0014 18.5 4.2 0.0014 18.5 4.2 5.2 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ48731.1 - 0.0063 16.3 4.7 0.0063 16.3 4.7 5.3 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 KXZ48732.1 - 1.7e-07 31.8 7.4 0.0016 19.2 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ48732.1 - 0.0051 17.1 0.0 4.6 7.6 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Guanylate_cyc PF00211.20 KXZ48733.1 - 3.3e-16 59.4 0.0 1.3e-05 24.9 0.0 3.3 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain SBP_bac_8 PF13416.6 KXZ48733.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Bap31 PF05529.12 KXZ48734.1 - 3.1e-05 23.9 0.1 3.6e-05 23.6 0.1 1.0 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Jas PF16135.5 KXZ48735.1 - 7.7e-11 42.0 13.6 1.6e-09 37.8 0.2 3.3 3 0 0 3 3 3 2 TPL-binding domain in jasmonate signalling PHD PF00628.29 KXZ48735.1 - 3.2e-05 23.7 7.1 3.2e-05 23.7 7.1 2.7 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 KXZ48735.1 - 0.33 10.9 19.4 0.17 11.8 3.5 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KXZ48735.1 - 0.86 9.7 22.4 3.4 7.8 5.4 2.5 2 0 0 2 2 2 0 PHD-finger Ins134_P3_kin PF05770.11 KXZ48736.1 - 1.3e-44 152.2 0.0 4.1e-24 85.2 0.0 2.2 2 0 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 KXZ48736.1 - 7.3e-15 55.1 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain DUF1214 PF06742.11 KXZ48737.1 - 1.4e-05 25.5 0.0 2.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) Pkinase PF00069.25 KXZ48738.1 - 6.1e-65 219.2 0.0 7.8e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48738.1 - 1.4e-36 126.2 0.0 2.5e-35 122.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ48738.1 - 0.0051 16.2 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ48738.1 - 0.014 15.3 0.1 0.014 15.3 0.1 3.7 2 2 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ48738.1 - 0.25 10.2 0.0 0.45 9.4 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KXZ48739.1 - 4.4e-25 88.5 0.0 5.2e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48739.1 - 2.1e-12 46.9 0.0 2.6e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ48740.1 - 5.8e-17 61.9 0.0 6.5e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48740.1 - 2.6e-08 33.5 0.0 2.8e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ48741.1 - 6.9e-23 81.3 0.0 4.1e-14 52.6 0.0 3.0 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48741.1 - 4.5e-09 36.0 0.0 2.9e-06 26.8 0.0 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KXZ48741.1 - 0.016 15.1 0.1 0.069 13.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ48742.1 - 1.3e-56 191.9 0.0 1.6e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48742.1 - 9.1e-31 107.1 0.0 7.7e-30 104.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ48742.1 - 0.00039 19.8 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ48742.1 - 0.00061 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ48742.1 - 0.008 15.2 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXZ48742.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXZ48742.1 - 0.054 12.3 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ48742.1 - 0.089 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ACPS PF01648.20 KXZ48743.1 - 1.2e-16 60.9 0.0 3.2e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily IATP PF04568.12 KXZ48743.1 - 6.2 7.3 8.6 1.8 9.1 2.2 2.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP zf-HC5HC2H PF13771.6 KXZ48744.1 - 6.5e-10 39.1 6.6 1.9e-09 37.6 6.6 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain SAND PF01342.21 KXZ48744.1 - 3.9e-08 32.9 0.0 1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 SAND domain zf-HC5HC2H_2 PF13832.6 KXZ48744.1 - 2.4e-05 24.5 8.8 2.4e-05 24.5 8.8 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain ICMT PF04140.14 KXZ48745.1 - 4.4e-26 91.1 0.7 5.3e-26 90.9 0.7 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXZ48745.1 - 3.3e-09 37.1 0.7 4e-09 36.8 0.7 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KXZ48745.1 - 3.6e-05 23.4 0.3 3.9e-05 23.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KXZ48745.1 - 0.0047 16.5 0.4 0.0061 16.1 0.4 1.4 1 1 0 1 1 1 1 NnrU protein DSPc PF00782.20 KXZ48747.1 - 9.4e-10 38.4 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KXZ48747.1 - 0.0014 18.7 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KXZ48747.1 - 0.072 12.6 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TFIIS_C PF01096.18 KXZ48749.1 - 1.2e-17 63.4 2.0 2e-17 62.7 2.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TackOD1 PF18551.1 KXZ48749.1 - 0.0021 17.8 0.1 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 RNA_POL_M_15KD PF02150.16 KXZ48749.1 - 0.015 15.2 5.7 0.43 10.5 4.5 3.0 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KXZ48749.1 - 0.021 14.8 2.9 0.04 13.9 2.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Terminase_GpA PF05876.12 KXZ48749.1 - 0.026 13.1 0.6 0.03 12.9 0.6 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-Mss51 PF13824.6 KXZ48749.1 - 0.027 14.6 4.7 0.078 13.1 0.7 3.0 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-TFIIB PF13453.6 KXZ48749.1 - 0.033 13.5 1.2 0.079 12.3 1.2 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Lar_restr_allev PF14354.6 KXZ48749.1 - 0.038 14.4 1.1 0.081 13.3 1.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 KXZ48749.1 - 0.065 13.0 4.8 2.4 8.0 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KXZ48749.1 - 0.088 12.9 7.6 3.4 7.9 1.7 3.1 4 0 0 4 4 4 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KXZ48749.1 - 0.1 12.2 1.7 8.7 6.0 0.0 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4379 PF14311.6 KXZ48749.1 - 0.17 12.3 3.4 0.63 10.5 0.2 2.5 1 1 1 2 2 2 0 Probable Zinc-ribbon domain DZR PF12773.7 KXZ48749.1 - 0.21 11.6 3.7 1.3 9.1 2.6 2.4 2 1 0 2 2 2 0 Double zinc ribbon Baculo_LEF5_C PF11792.8 KXZ48749.1 - 0.28 10.9 3.0 0.44 10.3 1.4 2.0 1 1 1 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-ribbon_3 PF13248.6 KXZ48749.1 - 0.37 10.3 7.9 5.6 6.5 0.4 3.5 4 0 0 4 4 4 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KXZ48749.1 - 0.93 9.3 7.7 0.57 10.0 2.4 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ogr_Delta PF04606.12 KXZ48749.1 - 3 7.9 7.7 15 5.7 7.7 2.1 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger LRR_8 PF13855.6 KXZ48750.1 - 2.4e-42 142.5 16.4 1.5e-10 40.6 0.2 6.7 3 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 KXZ48750.1 - 1.8e-35 120.4 0.2 3.8e-05 23.9 0.1 8.5 7 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ48750.1 - 3.7e-13 48.0 9.8 6.7 7.7 0.6 11.2 11 2 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 KXZ48750.1 - 3e-11 42.4 17.0 1.9 8.8 0.1 10.8 13 0 0 13 13 13 5 Leucine Rich repeat LRR_9 PF14580.6 KXZ48750.1 - 4.1e-06 26.4 0.0 0.7 9.4 0.0 3.8 2 2 1 3 3 3 2 Leucine-rich repeat SBDS_C PF09377.10 KXZ48751.1 - 1.3e-31 109.0 0.0 2e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KXZ48751.1 - 2.5e-30 104.4 0.4 4e-30 103.7 0.4 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MBD PF01429.19 KXZ48751.1 - 0.038 13.7 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyl-CpG binding domain DUF1216 PF06746.11 KXZ48751.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) DNA_pol_E_B PF04042.16 KXZ48752.1 - 7e-26 90.9 0.0 1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KXZ48752.1 - 1.5e-06 28.4 0.0 2.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal 4F5 PF04419.14 KXZ48753.1 - 2.4e-05 25.1 8.5 3.2e-05 24.7 8.5 1.1 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.7 KXZ48753.1 - 0.0013 18.8 4.0 0.0025 17.9 4.0 1.5 1 0 0 1 1 1 1 Zinc-binding CobT PF06213.12 KXZ48755.1 - 4.6 6.6 13.2 6.1 6.2 13.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4399 PF14347.6 KXZ48756.1 - 2.3e-23 82.4 0.1 3.1e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4399) PEGA PF08308.11 KXZ48756.1 - 0.13 12.2 0.1 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 PEGA domain Y_Y_Y PF07495.13 KXZ48756.1 - 0.27 11.2 0.0 0.46 10.5 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain PPTA PF01239.22 KXZ48757.1 - 3.9e-33 112.2 20.8 1.2e-07 31.2 0.0 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat HopW1-1 PF15457.6 KXZ48757.1 - 0.078 12.2 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA DUF4219 PF13961.6 KXZ48757.1 - 9.4 6.0 8.2 4.8 7.0 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Mito_carr PF00153.27 KXZ48758.1 - 6.2e-28 96.6 0.4 4.4e-15 55.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_1 PF00561.20 KXZ48759.1 - 8.2e-06 25.6 0.0 0.00017 21.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ48759.1 - 0.0013 18.1 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KXZ48759.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase UPF0227 PF05728.12 KXZ48759.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FKBP_C PF00254.28 KXZ48761.1 - 1.7e-15 57.1 0.0 1e-06 29.0 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_8 PF13181.6 KXZ48761.1 - 2.7e-11 42.8 1.3 0.00011 22.1 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ48761.1 - 4.7e-11 41.9 12.7 2.1e-05 24.3 0.6 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ48761.1 - 2.2e-09 36.7 8.0 6.8e-05 22.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ48761.1 - 2e-06 28.2 1.9 5.9e-06 26.7 1.9 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ48761.1 - 1e-05 26.0 10.9 1.8e-05 25.3 3.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ48761.1 - 2.7e-05 23.7 6.1 0.047 13.4 0.3 3.4 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.6 KXZ48761.1 - 3.1e-05 23.7 5.2 0.052 13.6 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ48761.1 - 7.8e-05 22.8 0.1 0.00027 21.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ48761.1 - 0.0012 19.5 8.2 0.042 14.7 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ48761.1 - 0.0015 18.8 11.7 0.0057 16.9 4.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ48761.1 - 0.0055 16.8 1.5 0.0055 16.8 1.5 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ48761.1 - 0.0095 16.0 0.1 0.0095 16.0 0.1 3.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KXZ48761.1 - 0.028 14.7 1.8 0.028 14.7 1.8 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 KXZ48761.1 - 0.033 13.1 0.1 0.046 12.6 0.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KXZ48761.1 - 0.15 12.8 5.4 6.4 7.7 1.5 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ48761.1 - 0.15 12.7 5.6 2.7 8.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 KXZ48761.1 - 0.17 11.9 0.4 0.48 10.5 0.4 1.7 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Ribosomal_S21 PF01165.20 KXZ48762.1 - 0.0048 16.6 9.8 0.0079 15.9 9.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 DUF3886 PF13025.6 KXZ48762.1 - 0.1 12.8 0.6 0.16 12.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) SET PF00856.28 KXZ48763.1 - 0.0016 18.8 0.0 0.0079 16.6 0.0 2.0 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KXZ48763.1 - 0.058 14.1 1.4 0.21 12.3 0.5 2.4 2 1 0 2 2 2 0 Rubisco LSMT substrate-binding Lipase_GDSL_2 PF13472.6 KXZ48764.1 - 3.9e-07 30.6 0.0 9.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ZipA_C PF04354.13 KXZ48764.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain SR-25 PF10500.9 KXZ48764.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chloroa_b-bind PF00504.21 KXZ48765.1 - 7.2e-10 39.6 0.1 0.00012 22.7 0.0 2.1 1 1 1 2 2 2 2 Chlorophyll A-B binding protein G3P_acyltransf PF02660.15 KXZ48765.1 - 0.64 10.1 3.6 9 6.3 0.2 2.1 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase Pkinase PF00069.25 KXZ48766.1 - 2.3e-54 184.5 0.7 2.5e-38 132.0 0.1 3.0 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48766.1 - 5e-39 134.1 0.0 4e-26 91.8 0.0 3.2 2 1 1 3 3 3 2 Protein tyrosine kinase Arm PF00514.23 KXZ48766.1 - 0.0016 18.4 9.3 8.7 6.5 0.0 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat FTA2 PF13095.6 KXZ48766.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXZ48766.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CK_II_beta PF01214.18 KXZ48767.1 - 1.3e-74 249.9 0.4 1.8e-74 249.5 0.4 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Kinocilin PF15033.6 KXZ48767.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinocilin protein Aldolase_II PF00596.21 KXZ48768.1 - 1.3e-43 149.1 0.0 2.1e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 KXZ48768.1 - 0.041 14.2 0.1 0.086 13.1 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.14 KXZ48769.1 - 3.3e-58 197.3 3.4 8.6e-58 195.9 3.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXZ48769.1 - 1.3e-25 89.8 0.1 4.6e-25 88.0 0.1 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXZ48769.1 - 5.6e-12 46.0 0.0 5.6e-12 46.0 0.0 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXZ48769.1 - 5.6e-06 25.7 1.7 5.6e-06 25.7 1.7 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.6 KXZ48769.1 - 0.011 15.0 0.0 0.031 13.4 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 KXZ48769.1 - 0.041 13.5 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KXZ48769.1 - 4.6 6.4 7.0 26 3.9 5.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2OG-FeII_Oxy PF03171.20 KXZ48770.1 - 3.2e-07 30.8 0.0 6.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rad60-SLD PF11976.8 KXZ48770.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ank_2 PF12796.7 KXZ48773.1 - 5.6e-10 39.7 0.1 0.32 11.6 0.0 5.0 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48773.1 - 1.2e-06 29.0 5.4 9.1 7.0 0.0 7.2 5 3 4 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48773.1 - 1.6e-06 28.0 5.7 1.1e+02 3.9 0.0 10.0 12 0 0 12 12 12 0 Ankyrin repeat PHY PF00360.20 KXZ48773.1 - 0.034 13.4 0.1 0.091 12.1 0.1 1.7 1 0 0 1 1 1 0 Phytochrome region Ank_5 PF13857.6 KXZ48773.1 - 1.4 9.3 9.5 6.6 7.2 0.0 5.6 8 1 1 9 9 9 0 Ankyrin repeats (many copies) 2OG-FeII_Oxy PF03171.20 KXZ48774.1 - 9.2e-07 29.3 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mlo PF03094.15 KXZ48776.1 - 7.2e-30 103.8 11.4 1e-11 43.9 0.1 3.9 3 1 0 3 3 3 3 Mlo family PROCN PF08083.11 KXZ48777.1 - 1.6e-234 778.0 8.6 2.7e-234 777.3 8.6 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KXZ48777.1 - 6.4e-129 428.4 0.5 1.1e-128 427.7 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KXZ48777.1 - 1.7e-88 294.5 3.0 6.9e-88 292.6 2.7 2.2 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KXZ48777.1 - 4.8e-87 289.6 4.9 4.8e-87 289.6 4.9 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KXZ48777.1 - 2e-72 241.6 0.0 3.9e-72 240.6 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KXZ48777.1 - 2.7e-52 175.9 0.0 7.9e-52 174.4 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KXZ48777.1 - 1.2e-47 160.1 0.2 3.1e-47 158.8 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 KXZ48777.1 - 3.9e-06 26.8 0.0 1.1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Sua5_yciO_yrdC PF01300.18 KXZ48779.1 - 1.1e-37 129.3 0.0 1.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination SET PF00856.28 KXZ48781.1 - 2e-10 41.3 0.0 6.9e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KXZ48781.1 - 0.0059 16.7 14.2 0.0098 16.0 14.2 1.4 1 0 0 1 1 1 1 MYND finger L27 PF02828.16 KXZ48782.1 - 0.026 14.3 0.2 0.61 9.9 0.1 3.0 2 0 0 2 2 2 0 L27 domain Beta_helix PF13229.6 KXZ48783.1 - 1.8e-09 37.6 15.6 0.0048 16.8 0.3 7.9 7 1 0 7 7 7 4 Right handed beta helix region CDC45 PF02724.14 KXZ48783.1 - 0.42 8.8 0.3 0.59 8.4 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TRP PF06011.12 KXZ48784.1 - 0.00031 19.6 14.2 0.0014 17.5 14.2 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel MG4 PF17789.1 KXZ48784.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Macroglobulin domain MG4 GOLD_2 PF13897.6 KXZ48784.1 - 0.43 11.1 1.2 0.82 10.2 1.2 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CAC1F_C PF16885.5 KXZ48784.1 - 0.84 9.2 2.8 1.2 8.7 2.8 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Hydrolase_4 PF12146.8 KXZ48785.1 - 3.9e-52 176.9 0.0 4.6e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ48785.1 - 8.6e-19 69.0 11.1 1.1e-18 68.7 11.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ48785.1 - 4.3e-17 62.6 0.0 3.7e-14 53.0 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXZ48785.1 - 7.8e-07 28.8 0.1 0.023 14.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXZ48785.1 - 0.00011 22.1 1.3 0.00023 21.1 1.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXZ48785.1 - 0.0078 15.8 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.13 KXZ48785.1 - 0.12 12.2 0.2 0.41 10.5 0.0 1.9 1 1 1 2 2 2 0 Serine hydrolase Beta_helix PF13229.6 KXZ48786.1 - 0.023 14.6 31.6 0.056 13.3 0.7 7.4 5 2 1 6 6 6 0 Right handed beta helix region MG4 PF17789.1 KXZ48786.1 - 0.23 11.6 0.0 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 Macroglobulin domain MG4 TRP PF06011.12 KXZ48786.1 - 0.25 10.0 9.7 1.3 7.7 9.7 1.9 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Glyco_transf_90 PF05686.12 KXZ48787.1 - 2.7e-08 33.1 0.0 6e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 EF-hand_7 PF13499.6 KXZ48789.1 - 1.1e-11 44.9 0.2 1.6e-11 44.5 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ48789.1 - 2.4e-08 33.3 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXZ48789.1 - 1.3e-07 30.6 0.0 5.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXZ48789.1 - 2.5e-07 30.4 0.1 9.2e-07 28.6 0.0 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 KXZ48789.1 - 0.0007 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 EF hand HEAT PF02985.22 KXZ48792.1 - 8.4e-34 112.7 58.2 0.0086 16.3 0.1 22.4 26 0 0 26 26 25 9 HEAT repeat HEAT_EZ PF13513.6 KXZ48792.1 - 3.5e-16 59.3 129.4 0.00017 22.0 0.1 25.9 23 6 7 30 30 28 10 HEAT-like repeat HEAT_2 PF13646.6 KXZ48792.1 - 4e-16 59.2 115.4 3.7e-06 27.2 0.1 20.7 16 5 4 21 21 21 7 HEAT repeats CLASP_N PF12348.8 KXZ48792.1 - 2.3e-13 50.3 0.0 4.1e-05 23.3 0.0 8.0 9 2 1 10 10 10 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 KXZ48792.1 - 4e-10 40.2 0.0 2.4 8.8 0.0 7.9 9 0 0 9 9 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXZ48792.1 - 3.2e-08 33.8 0.0 0.92 9.5 0.0 7.0 5 1 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 KXZ48792.1 - 6.8e-07 29.5 9.0 0.1 12.9 0.0 7.3 8 0 0 8 8 8 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KXZ48792.1 - 0.0019 16.8 0.0 1.5 7.3 0.0 4.3 4 0 0 4 4 4 1 Adaptin N terminal region MMS19_C PF12460.8 KXZ48792.1 - 0.0031 16.7 0.1 1.6 7.8 0.0 4.2 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF3437 PF11919.8 KXZ48792.1 - 0.0036 17.2 2.5 0.3 11.0 0.0 5.4 6 0 0 6 6 6 1 Domain of unknown function (DUF3437) IFRD PF05004.13 KXZ48792.1 - 0.0098 15.0 6.6 5.8 5.9 0.1 6.3 6 1 0 6 6 6 1 Interferon-related developmental regulator (IFRD) DUF3535 PF12054.8 KXZ48792.1 - 0.042 13.1 0.0 0.72 9.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) Sen15 PF09631.10 KXZ48794.1 - 0.018 15.4 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 Sen15 protein Methyltransf_25 PF13649.6 KXZ48795.1 - 2.8e-07 31.1 0.1 8.7e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ48795.1 - 3.2e-07 30.9 0.1 6.1e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ48795.1 - 0.00012 22.0 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NIPSNAP PF07978.13 KXZ48796.1 - 2e-36 124.3 0.0 1.7e-19 69.9 0.1 2.1 2 0 0 2 2 2 2 NIPSNAP HpcH_HpaI PF03328.14 KXZ48797.1 - 1.8e-28 99.2 0.0 3.9e-28 98.1 0.0 1.5 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C2 PF00168.30 KXZ48798.1 - 2.9e-19 69.2 0.0 3.8e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 C2 domain DUF760 PF05542.11 KXZ48799.1 - 5.6e-33 113.2 0.4 4.6e-19 68.6 0.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Formyl_trans_N PF00551.19 KXZ48799.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase DNA_pol_B_exo1 PF03104.19 KXZ48800.1 - 3.3e-05 23.2 0.0 3.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo1 PF03104.19 KXZ48801.1 - 8.1e-25 87.7 0.2 1.2e-24 87.2 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KXZ48801.1 - 9e-10 37.8 0.0 1.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B RNase_H_2 PF13482.6 KXZ48801.1 - 0.00063 19.8 0.2 0.0057 16.7 0.2 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 KXZ48801.1 - 0.0038 16.9 0.2 0.0062 16.3 0.2 1.5 1 1 0 1 1 1 1 3'-5' exonuclease DNA_pol_B PF00136.21 KXZ48802.1 - 2e-33 115.8 0.0 2.4e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B DUF723 PF05265.13 KXZ48802.1 - 0.0043 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF723) AAA_16 PF13191.6 KXZ48803.1 - 0.053 13.9 0.8 0.21 11.9 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain MutS_V PF00488.21 KXZ48804.1 - 3.8e-29 102.1 0.4 7e-28 97.9 0.4 2.2 1 1 0 1 1 1 1 MutS domain V AAA_21 PF13304.6 KXZ48804.1 - 0.19 11.5 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system START PF01852.19 KXZ48806.1 - 0.0053 16.2 0.1 0.0099 15.3 0.1 1.4 1 0 0 1 1 1 1 START domain AA_kinase PF00696.28 KXZ48807.1 - 1.9e-44 152.1 3.5 2.4e-44 151.8 3.5 1.1 1 0 0 1 1 1 1 Amino acid kinase family Pkinase_Tyr PF07714.17 KXZ48810.1 - 3.5e-60 203.5 0.0 6e-30 104.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ48810.1 - 1.6e-29 103.1 0.0 8.4e-18 64.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ48810.1 - 0.00019 20.9 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ48810.1 - 0.012 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ48811.1 - 2e-19 70.0 0.0 2.6e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ48811.1 - 2e-10 40.0 0.0 2.7e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ48811.1 - 2.4e-10 40.2 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ48811.1 - 0.00098 19.1 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ48811.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2OG-FeII_Oxy_3 PF13640.6 KXZ48812.1 - 2e-14 54.2 0.2 4.7e-14 53.0 0.1 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 KXZ48812.1 - 0.0028 17.5 0.1 0.0069 16.2 0.1 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy PF03171.20 KXZ48812.1 - 0.0096 16.4 0.0 0.028 14.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 KXZ48812.1 - 0.018 15.6 8.9 0.18 12.4 8.9 2.3 1 1 0 1 1 1 0 ShK domain-like OAS1_C PF10421.9 KXZ48813.1 - 4.1e-08 32.9 0.1 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 2 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus DUF5591 PF17884.1 KXZ48813.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) OAS1_C PF10421.9 KXZ48814.1 - 3.4e-09 36.5 0.0 0.00021 20.8 0.0 2.3 2 0 0 2 2 2 2 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Ank_4 PF13637.6 KXZ48815.1 - 0.0066 17.0 0.2 1.7 9.3 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48815.1 - 0.064 13.9 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) HEAT PF02985.22 KXZ48816.1 - 9 6.9 7.2 8.4 7.0 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat Cys_Met_Meta_PP PF01053.20 KXZ48818.1 - 0.18 10.3 0.1 0.25 9.8 0.1 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme LMBR1 PF04791.16 KXZ48819.1 - 3.8e-49 168.0 36.0 9.9e-33 113.8 22.2 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein Piezo_RRas_bdg PF12166.8 KXZ48819.1 - 2.8 7.1 5.7 2.5 7.3 0.1 2.6 3 0 0 3 3 3 0 Piezo non-specific cation channel, R-Ras-binding domain CCSMST1 PF15013.6 KXZ48819.1 - 9.8 6.4 7.9 3.1 8.0 0.3 3.4 2 1 1 3 3 3 0 CCSMST1 family Peptidase_M3 PF01432.20 KXZ48820.1 - 3e-17 63.0 0.0 2.6e-16 59.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 KXZ48820.1 - 7.9e-08 31.4 0.1 1.1e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M32 PF02074.15 KXZ48820.1 - 0.064 12.0 0.2 4.7 5.9 0.0 2.9 3 0 0 3 3 3 0 Carboxypeptidase Taq (M32) metallopeptidase LRR_4 PF12799.7 KXZ48821.1 - 0.004 17.5 1.3 0.55 10.7 0.2 3.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ48821.1 - 0.32 10.8 6.2 1.5 8.7 2.1 3.1 2 1 1 3 3 3 0 Leucine rich repeat DNA_pol_phi PF04931.13 KXZ48821.1 - 2.1 6.4 4.0 3.3 5.7 4.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KXZ48821.1 - 8.4 6.1 5.9 13 5.4 5.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glucodextran_N PF09137.11 KXZ48822.1 - 0.0094 15.5 6.4 0.017 14.7 6.4 1.3 1 0 0 1 1 1 1 Glucodextranase, domain N TFIIA PF03153.13 KXZ48822.1 - 0.51 10.3 52.0 1.8 8.5 39.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Vma12 PF11712.8 KXZ48822.1 - 1.6 8.8 6.8 3.4 7.7 6.8 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase BORG_CEP PF14957.6 KXZ48822.1 - 3.5 8.8 10.2 27 5.9 7.9 2.3 2 0 0 2 2 2 0 Cdc42 effector Exonuc_VII_L PF02601.15 KXZ48822.1 - 8.5 5.8 21.9 3.8 7.0 19.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit LRR_4 PF12799.7 KXZ48823.1 - 1.4e-05 25.4 4.7 8.3 7.0 0.0 6.5 7 1 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ48823.1 - 0.56 10.0 15.3 0.11 12.3 0.3 5.1 5 0 0 5 5 5 0 Leucine rich repeat zf-MYND PF01753.18 KXZ48824.1 - 5.1e-09 36.1 9.5 1.1e-08 35.0 9.5 1.5 1 0 0 1 1 1 1 MYND finger CxC4 PF18717.1 KXZ48824.1 - 0.82 9.5 2.8 1.7 8.5 2.8 1.4 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases UvrD-helicase PF00580.21 KXZ48825.1 - 1.4e-52 179.2 0.0 4e-52 177.7 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KXZ48825.1 - 7.9e-33 113.8 0.0 1e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ48825.1 - 1.1e-05 25.2 0.4 0.015 15.0 0.5 2.2 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KXZ48825.1 - 0.023 14.2 0.2 5.8 6.3 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein AAA_11 PF13086.6 KXZ48825.1 - 0.034 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KXZ48825.1 - 0.12 12.4 0.1 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain UvrD_C PF13361.6 KXZ48826.1 - 9.5e-33 114.0 0.0 1.1e-27 97.3 0.0 2.0 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KXZ48826.1 - 1.5e-09 37.5 0.0 4.4e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXZ48826.1 - 0.00016 21.5 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Ank_4 PF13637.6 KXZ48827.1 - 8.5e-08 32.6 0.5 3.1 8.5 0.0 7.0 6 1 2 8 8 8 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48827.1 - 1.7e-05 25.3 0.2 0.31 11.7 0.0 3.9 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ48827.1 - 0.0026 18.1 2.6 0.12 12.7 0.1 4.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) DUF434 PF04256.12 KXZ48827.1 - 0.016 14.9 0.2 0.81 9.4 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF434) Ank_2 PF12796.7 KXZ48828.1 - 1.8e-05 25.2 0.4 0.68 10.6 0.0 4.3 3 2 3 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48828.1 - 0.00026 21.5 3.3 11 6.7 0.0 6.3 6 2 2 8 8 8 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48828.1 - 0.00027 21.2 0.4 3 8.3 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) ABC_tran PF00005.27 KXZ48829.1 - 2.7e-43 147.8 0.0 1.2e-21 77.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXZ48829.1 - 1.4e-21 76.3 8.2 1.4e-21 76.3 8.2 2.9 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KXZ48829.1 - 2.7e-17 63.6 4.7 4.2e-06 26.8 0.1 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ48829.1 - 2.5e-08 33.6 0.4 0.28 10.6 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXZ48829.1 - 7.3e-07 29.5 0.0 0.0066 16.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXZ48829.1 - 8.6e-07 28.6 0.0 0.0048 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KXZ48829.1 - 1.3e-05 25.1 0.4 0.076 12.7 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 KXZ48829.1 - 4.7e-05 23.7 0.3 0.25 11.6 0.0 3.0 2 1 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 KXZ48829.1 - 0.00011 22.5 0.0 0.18 12.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KXZ48829.1 - 0.00014 21.9 0.0 1.1 9.2 0.0 3.1 3 1 1 4 4 3 2 AAA domain ATPase_2 PF01637.18 KXZ48829.1 - 0.00026 21.0 0.2 0.72 9.7 0.0 3.0 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea AAA PF00004.29 KXZ48829.1 - 0.00043 20.7 0.0 0.34 11.3 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KXZ48829.1 - 0.00055 20.0 0.0 0.066 13.3 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXZ48829.1 - 0.00062 19.7 1.1 0.15 11.9 0.0 3.0 3 1 0 3 3 2 1 RsgA GTPase AAA_18 PF13238.6 KXZ48829.1 - 0.00097 19.7 0.1 3 8.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KXZ48829.1 - 0.0011 19.2 0.0 0.75 9.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KXZ48829.1 - 0.0013 18.8 0.1 0.47 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KXZ48829.1 - 0.0022 18.5 14.8 0.0072 16.8 0.1 4.1 3 1 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KXZ48829.1 - 0.0027 18.1 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 KXZ48829.1 - 0.0028 17.3 0.2 0.78 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KXZ48829.1 - 0.0041 17.1 0.0 0.64 9.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 KXZ48829.1 - 0.0046 16.7 0.1 0.55 9.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KXZ48829.1 - 0.0056 16.4 0.0 1.1 8.9 0.0 3.3 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 KXZ48829.1 - 0.0056 16.6 0.2 1.4 8.8 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 KXZ48829.1 - 0.021 14.3 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KXZ48829.1 - 0.025 14.7 1.1 5 7.2 0.0 3.3 2 1 1 3 3 3 0 Dynamin family DUF87 PF01935.17 KXZ48829.1 - 0.032 14.3 0.4 1.2 9.2 0.0 2.8 3 1 0 3 3 3 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KXZ48829.1 - 0.061 12.7 0.1 11 5.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 KXZ48829.1 - 0.067 13.4 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KXZ48829.1 - 0.084 12.4 0.5 6.4 6.3 0.0 3.4 3 1 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 KXZ48829.1 - 0.18 11.5 0.6 4.7 6.9 0.0 2.5 2 1 0 2 2 2 0 Cytidylate kinase TsaE PF02367.17 KXZ48829.1 - 0.23 11.5 1.0 15 5.6 0.0 3.3 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_S19e PF01090.19 KXZ48830.1 - 1.7e-56 189.7 0.0 1.9e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 KXZ48830.1 - 0.0058 16.6 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_5 PF01022.20 KXZ48830.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family FHA PF00498.26 KXZ48831.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 FHA domain Tropomyosin_1 PF12718.7 KXZ48832.1 - 0.0017 18.5 1.9 0.0028 17.8 1.9 1.2 1 0 0 1 1 1 1 Tropomyosin like AA_permease_2 PF13520.6 KXZ48834.1 - 7.3e-41 140.4 40.8 8.4e-41 140.2 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXZ48834.1 - 3.1e-11 42.6 30.7 5.1e-11 41.8 30.7 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXZ48835.1 - 1.6e-41 142.5 35.2 2e-41 142.2 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXZ48835.1 - 7.5e-11 41.3 31.4 1.4e-10 40.4 31.4 1.4 1 1 0 1 1 1 1 Amino acid permease Prok-E2_E PF14462.6 KXZ48835.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E Epimerase PF01370.21 KXZ48836.1 - 8.5e-07 28.7 0.0 1.8e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXZ48836.1 - 0.0079 15.4 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXZ48837.1 - 1.8e-19 70.2 0.0 2.5e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXZ48837.1 - 9.9e-13 48.4 0.0 1.4e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXZ48837.1 - 9.2e-09 34.7 0.0 1.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXZ48837.1 - 3.6e-07 29.6 0.0 1.6e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KXZ48837.1 - 3.8e-06 26.6 0.0 6.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXZ48837.1 - 3.5e-05 23.3 0.0 4.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase LRR_9 PF14580.6 KXZ48838.1 - 2e-41 141.4 11.4 1.7e-09 37.5 0.0 7.2 4 3 3 7 7 7 7 Leucine-rich repeat LRR_4 PF12799.7 KXZ48838.1 - 5.4e-41 137.9 31.7 0.00095 19.5 0.1 11.3 9 3 1 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ48838.1 - 1.1e-33 114.7 49.1 4.9e-09 35.8 2.0 10.0 8 1 2 10 10 10 7 Leucine rich repeat LRR_6 PF13516.6 KXZ48838.1 - 1.3e-07 31.1 20.1 4.2 7.7 0.0 11.4 12 0 0 12 12 12 3 Leucine Rich repeat LRR_1 PF00560.33 KXZ48838.1 - 0.016 15.7 22.3 9.8 7.2 0.0 10.3 11 1 0 11 11 11 0 Leucine Rich Repeat Ank_2 PF12796.7 KXZ48839.1 - 1.6e-05 25.4 0.1 0.15 12.7 0.0 3.7 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48839.1 - 0.00015 22.3 0.4 2.3 8.9 0.0 4.8 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48839.1 - 0.013 16.0 0.2 25 5.9 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeat Ank_4 PF13637.6 KXZ48840.1 - 4.4e-05 23.9 0.5 43 4.8 0.0 6.7 6 2 1 7 7 7 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48840.1 - 0.0004 20.9 0.0 6.9 7.3 0.0 4.1 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48840.1 - 0.003 17.9 0.3 2.4e+02 2.8 0.0 6.4 7 0 0 7 7 7 0 Ankyrin repeat ATX_III PF08098.11 KXZ48840.1 - 1.7 8.8 8.1 11 6.2 0.2 3.4 3 0 0 3 3 3 0 Anemonia sulcata toxin III family Ank_2 PF12796.7 KXZ48841.1 - 2.6e-05 24.7 0.0 3.8 8.2 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ48841.1 - 0.69 10.3 4.7 18 5.8 0.1 5.1 4 2 2 6 6 6 0 Ankyrin repeats (many copies) ATX_III PF08098.11 KXZ48841.1 - 1.8 8.6 7.5 18 5.4 0.3 3.7 2 0 0 2 2 2 0 Anemonia sulcata toxin III family YqgC PF17430.2 KXZ48842.1 - 0.096 12.8 1.0 0.28 11.3 1.0 1.8 1 1 0 1 1 1 0 Uncharacterized YqgC-like Pkinase_Tyr PF07714.17 KXZ48843.1 - 4e-44 150.8 0.0 6.1e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ48843.1 - 4.9e-43 147.4 0.0 7e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PAN_4 PF14295.6 KXZ48843.1 - 4.6e-19 68.1 48.8 0.00088 19.1 0.7 8.1 8 0 0 8 8 8 6 PAN domain Lectin_C PF00059.21 KXZ48843.1 - 1.7e-16 60.9 0.0 0.085 13.6 0.0 6.0 5 0 0 5 5 5 5 Lectin C-type domain PAN_1 PF00024.26 KXZ48843.1 - 6.7e-16 58.0 28.5 0.0004 20.3 2.5 7.5 8 0 0 8 8 8 5 PAN domain WSC PF01822.19 KXZ48843.1 - 0.00093 19.3 0.1 0.00093 19.3 0.1 5.0 5 0 0 5 5 4 1 WSC domain APH PF01636.23 KXZ48843.1 - 0.0059 16.6 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family UL45 PF05473.12 KXZ48843.1 - 0.032 13.9 0.1 22 4.6 0.0 4.1 4 0 0 4 4 4 0 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KXZ48843.1 - 0.046 14.1 4.8 95 3.5 0.0 5.3 5 0 0 5 5 4 0 Extracellular link domain DUF4690 PF15756.5 KXZ48843.1 - 0.12 12.9 0.7 0.41 11.3 0.7 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage MANEC PF07502.14 KXZ48843.1 - 6.2 7.2 30.3 2.7 8.3 0.4 6.1 6 0 0 6 6 5 0 MANEC domain V_ATPase_I PF01496.19 KXZ48844.1 - 0.00023 19.3 0.4 0.0003 18.9 0.4 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4013 PF13197.6 KXZ48844.1 - 0.28 11.0 6.7 0.72 9.7 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) zf-MYND PF01753.18 KXZ48845.1 - 2.2e-09 37.2 19.4 3.6e-09 36.6 19.4 1.3 1 0 0 1 1 1 1 MYND finger TPR_MalT PF17874.1 KXZ48845.1 - 8.4e-07 28.7 3.3 1.3e-06 28.1 3.3 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 KXZ48845.1 - 1.5e-06 28.4 2.5 0.0026 18.0 1.1 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ48845.1 - 0.0001 21.9 0.0 0.85 9.6 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ48845.1 - 0.00014 21.7 1.0 2.7 8.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ48845.1 - 0.0023 17.8 0.1 1.9 8.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Ecl1 PF12855.7 KXZ48845.1 - 0.0025 19.0 1.2 0.0025 19.0 1.2 2.2 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins TPR_8 PF13181.6 KXZ48845.1 - 0.0034 17.5 0.0 0.86 10.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ48845.1 - 0.26 12.2 9.9 1.4 10.0 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 KXZ48845.1 - 1.4 9.2 13.0 3.1 8.2 13.0 1.6 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Acyl-CoA_dh_1 PF00441.24 KXZ48846.1 - 2.7e-41 141.2 0.8 5.5e-41 140.3 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXZ48846.1 - 1.1e-23 84.0 0.1 2.8e-23 82.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXZ48846.1 - 2.2e-18 66.9 0.9 3.8e-18 66.0 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXZ48846.1 - 6.3e-14 52.0 0.0 2.4e-12 46.9 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Peptidase_C48 PF02902.19 KXZ48847.1 - 4.4e-16 59.4 0.0 9.5e-13 48.5 0.0 3.0 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 KXZ48848.1 - 2.5e-07 31.3 1.4 0.0085 16.9 0.0 5.1 4 0 0 4 4 4 1 WD domain, G-beta repeat HELP PF03451.14 KXZ48848.1 - 1.7e-05 24.6 0.1 0.0017 18.2 0.1 2.5 2 0 0 2 2 2 2 HELP motif EF-hand_1 PF00036.32 KXZ48848.1 - 0.0091 15.5 0.0 0.039 13.5 0.0 2.1 2 0 0 2 2 2 1 EF hand PAS PF00989.25 KXZ48850.1 - 6.8e-12 45.4 0.0 0.00022 21.2 0.0 5.1 4 1 1 5 5 5 3 PAS fold PAS_4 PF08448.10 KXZ48850.1 - 4.9e-11 42.9 0.9 0.054 13.7 0.0 5.9 6 0 0 6 6 6 3 PAS fold PAS_9 PF13426.7 KXZ48850.1 - 2.9e-10 40.3 0.0 0.00032 20.9 0.0 5.2 5 0 0 5 5 5 1 PAS domain PAS_8 PF13188.7 KXZ48850.1 - 0.00011 22.1 0.0 0.071 13.2 0.0 3.5 3 0 0 3 3 3 1 PAS domain TPR_14 PF13428.6 KXZ48850.1 - 0.098 13.5 0.2 2.6 9.1 0.1 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ48850.1 - 0.1 13.1 0.1 0.65 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Arf PF00025.21 KXZ48851.1 - 7.1e-43 146.1 0.0 1.2e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXZ48851.1 - 3.6e-09 36.3 0.3 1.5e-05 24.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ank_2 PF12796.7 KXZ48851.1 - 7.3e-09 36.1 0.0 0.12 13.0 0.0 5.0 2 2 5 7 7 7 4 Ankyrin repeats (3 copies) Roc PF08477.13 KXZ48851.1 - 2e-08 34.5 0.0 3.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_4 PF13637.6 KXZ48851.1 - 8.1e-08 32.7 0.0 0.38 11.4 0.0 6.0 5 1 1 6 6 6 3 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 KXZ48851.1 - 1.2e-07 31.8 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXZ48851.1 - 7.2e-07 28.9 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KXZ48851.1 - 1.3e-06 28.0 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ank_3 PF13606.6 KXZ48851.1 - 8.8e-06 25.7 0.0 16 6.5 0.0 7.1 7 0 0 7 7 7 0 Ankyrin repeat Gtr1_RagA PF04670.12 KXZ48851.1 - 0.0003 20.2 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1682 PF07946.14 KXZ48851.1 - 0.011 15.0 2.3 0.018 14.3 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ABC_tran PF00005.27 KXZ48851.1 - 0.023 15.2 0.1 0.023 15.2 0.1 1.8 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 KXZ48851.1 - 0.049 13.7 0.0 19 5.3 0.0 3.0 3 0 0 3 3 3 0 Dynamin family AAA_21 PF13304.6 KXZ48851.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXZ48851.1 - 0.18 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KXZ48851.1 - 0.18 11.3 0.3 0.35 10.4 0.3 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B FAD_binding_4 PF01565.23 KXZ48852.1 - 1.4 8.7 6.4 8.6 6.1 0.7 2.4 2 0 0 2 2 2 0 FAD binding domain LRR_6 PF13516.6 KXZ48853.1 - 5.6e-48 156.9 43.9 2.7e-05 23.9 0.2 13.6 14 0 0 14 14 14 9 Leucine Rich repeat FtsJ PF01728.19 KXZ48853.1 - 1.8e-18 67.2 0.0 3.9e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase LRR_4 PF12799.7 KXZ48853.1 - 6.5e-15 55.0 8.5 0.021 15.2 0.0 8.0 6 2 3 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ48853.1 - 5.2e-10 38.5 0.0 16 6.5 0.1 9.8 13 1 0 13 13 13 1 Leucine Rich Repeat LRR_8 PF13855.6 KXZ48853.1 - 2.4e-05 24.0 23.5 4.9 7.0 0.8 9.4 4 3 4 8 8 8 5 Leucine rich repeat Methyltransf_23 PF13489.6 KXZ48853.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ48853.1 - 0.038 14.7 1.2 0.56 10.9 0.1 3.1 3 0 0 3 3 3 0 Methyltransferase domain Swi5 PF07061.11 KXZ48853.1 - 0.053 13.6 0.0 3.6 7.8 0.0 2.9 3 0 0 3 3 3 0 Swi5 Methyltransf_31 PF13847.6 KXZ48853.1 - 0.056 13.2 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.32 KXZ48854.1 - 4.4e-15 55.8 5.5 0.00046 20.9 0.1 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ48854.1 - 0.0012 19.0 0.0 12 6.3 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CoA_binding_3 PF13727.6 KXZ48855.1 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 CoA-binding domain Arteri_Gl PF00951.18 KXZ48855.1 - 0.1 12.4 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF2207 PF09972.9 KXZ48855.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 KXZ48855.1 - 5.6 6.5 6.3 14 5.2 6.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pro_isomerase PF00160.21 KXZ48859.1 - 2.2e-09 37.8 0.0 3.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD QSregVF_b PF12843.7 KXZ48860.1 - 2.8e-07 30.3 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor EP400_N PF15790.5 KXZ48860.1 - 0.072 11.9 0.5 0.14 10.9 0.5 1.4 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal PARP PF00644.20 KXZ48861.1 - 8.2e-19 68.0 0.0 2.1e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KXZ48861.1 - 4.8e-06 26.3 0.0 3.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme CCDC144C PF14915.6 KXZ48861.1 - 0.1 11.7 1.3 0.15 11.1 1.3 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Flavin_Reduct PF01613.18 KXZ48862.1 - 0.026 14.6 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 Flavin reductase like domain Bromo_TP PF07524.13 KXZ48863.1 - 4.1e-17 61.9 0.5 5.2e-17 61.6 0.5 1.1 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 KXZ48863.1 - 1.1e-11 45.0 1.6 1.1e-11 45.0 1.6 1.8 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term TFIID-31kDa PF02291.15 KXZ48863.1 - 0.00034 20.7 0.1 0.00048 20.2 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 KXZ48863.1 - 0.0019 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TAF PF02969.17 KXZ48863.1 - 0.0021 18.2 0.2 0.003 17.7 0.2 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KXZ48863.1 - 0.011 16.1 0.4 0.02 15.3 0.4 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Bromo_TP_like PF17027.5 KXZ48863.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Histone-fold protein CENP-S PF15630.6 KXZ48863.1 - 0.029 14.7 0.2 0.043 14.2 0.2 1.2 1 0 0 1 1 1 0 CENP-S protein Prominin PF05478.11 KXZ48865.1 - 6 4.7 5.0 0.65 7.9 0.2 1.6 2 0 0 2 2 2 0 Prominin Ank_4 PF13637.6 KXZ48866.1 - 1.5e-14 54.2 0.1 0.0075 16.8 0.0 6.9 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ48866.1 - 2.8e-09 37.4 0.0 0.8 10.3 0.0 5.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ48866.1 - 0.0022 18.3 4.0 12 6.8 0.0 6.8 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ48866.1 - 0.07 13.5 5.9 1.3e+02 3.1 0.0 6.1 6 1 1 7 7 7 0 Ankyrin repeats (many copies) HTH_39 PF14090.6 KXZ48866.1 - 0.073 12.8 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain DcpS_C PF11969.8 KXZ48867.1 - 8.2e-27 93.9 0.9 1.4e-26 93.2 0.9 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KXZ48867.1 - 7.6e-14 52.2 0.8 1.3e-13 51.5 0.8 1.4 1 0 0 1 1 1 1 HIT domain AAA_33 PF13671.6 KXZ48867.1 - 8.2e-12 45.5 0.0 9.1e-11 42.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain zf-C2HE PF16278.5 KXZ48867.1 - 7.7e-11 42.3 0.2 1.6e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger CPT PF07931.12 KXZ48867.1 - 0.0069 16.3 0.7 0.42 10.4 0.3 2.9 2 1 1 3 3 3 1 Chloramphenicol phosphotransferase-like protein zf-C2H2 PF00096.26 KXZ48867.1 - 0.088 13.3 0.1 0.088 13.3 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA_18 PF13238.6 KXZ48867.1 - 0.16 12.6 0.0 0.45 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF3795 PF12675.7 KXZ48867.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) Mpv17_PMP22 PF04117.12 KXZ48868.1 - 7e-17 61.4 0.3 7e-17 61.4 0.3 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF347 PF03988.12 KXZ48868.1 - 0.03 14.5 0.0 0.1 12.8 0.0 2.1 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Transgly_assoc PF04226.13 KXZ48868.1 - 0.05 13.9 0.1 3.3 8.1 0.0 2.7 2 0 0 2 2 2 0 Transglycosylase associated protein DUF3449 PF11931.8 KXZ48869.1 - 2e-71 239.6 1.6 2e-71 239.6 1.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 KXZ48869.1 - 9.2e-27 92.5 2.3 2e-26 91.4 2.3 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 KXZ48869.1 - 7.8e-22 77.6 0.0 3.3e-21 75.6 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KXZ48869.1 - 6.2e-10 38.8 3.2 6.6e-10 38.7 0.7 2.3 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain Desulfoferrod_N PF06397.12 KXZ48869.1 - 0.22 11.1 0.9 0.47 10.1 0.9 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain TPR_12 PF13424.6 KXZ48870.1 - 1.4e-11 44.5 2.7 2.3e-11 43.8 1.5 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ48870.1 - 3.4e-09 36.1 3.2 0.0001 22.0 0.5 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ48870.1 - 1.4e-07 31.9 1.4 2.5e-06 27.9 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ48870.1 - 6.7e-07 29.0 6.1 0.013 15.5 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ48870.1 - 7.2e-06 25.7 0.6 0.03 14.4 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ48870.1 - 0.00026 21.0 7.1 0.0022 18.0 0.4 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ48870.1 - 0.0027 18.4 1.5 1.2 10.2 0.1 4.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ48870.1 - 0.0059 17.2 1.7 2.7 8.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ48870.1 - 0.018 15.2 0.5 0.065 13.5 0.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KXZ48870.1 - 0.057 12.8 1.8 0.086 12.3 1.8 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF5401 PF17380.2 KXZ48870.1 - 0.51 8.3 9.0 0.91 7.5 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5401) TPR_10 PF13374.6 KXZ48870.1 - 1 9.3 5.4 8.2 6.4 0.3 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.7 KXZ48871.1 - 2.1e-17 63.5 0.5 3e-07 30.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48871.1 - 2.6e-15 56.6 0.8 1.2e-05 25.7 0.1 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48871.1 - 1.6e-14 52.5 0.4 0.003 17.9 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ48871.1 - 5.6e-12 45.6 2.1 0.0044 17.3 0.1 4.3 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48871.1 - 2.9e-09 36.9 8.2 0.0036 17.7 0.1 4.6 3 1 1 4 4 4 2 Ankyrin repeat AAA_6 PF12774.7 KXZ48873.1 - 8.2e-111 370.1 0.3 2.8e-97 325.6 0.4 2.7 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ48873.1 - 2.3e-82 277.3 0.0 5.2e-82 276.1 0.0 1.6 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 KXZ48873.1 - 6.2e-34 117.1 0.0 9.8e-22 77.3 0.0 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 KXZ48873.1 - 9.7e-18 64.5 0.0 2.5e-07 30.8 0.0 5.0 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KXZ48873.1 - 8.4e-14 51.6 0.0 2.5e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXZ48873.1 - 8.8e-12 45.7 0.3 0.00063 20.2 0.0 4.5 3 0 0 3 3 3 3 AAA ATPase domain Dynein_AAA_lid PF17852.1 KXZ48873.1 - 4.7e-11 42.9 0.0 1.3e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KXZ48873.1 - 4.3e-07 30.4 0.1 0.35 11.3 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXZ48873.1 - 4.3e-06 27.3 0.0 0.062 13.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KXZ48873.1 - 7e-06 26.4 0.1 0.59 10.4 0.0 4.4 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 KXZ48873.1 - 0.00057 19.0 0.2 0.0054 15.8 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KXZ48873.1 - 0.00087 19.1 0.0 0.29 10.9 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein Rad17 PF03215.15 KXZ48873.1 - 0.0015 18.5 0.2 2.6 8.0 0.0 3.3 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_11 PF13086.6 KXZ48873.1 - 0.0061 16.4 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ48873.1 - 0.0085 16.5 0.0 23 5.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_29 PF13555.6 KXZ48873.1 - 0.023 14.4 0.1 0.41 10.4 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain NACHT PF05729.12 KXZ48873.1 - 0.034 14.1 1.2 31 4.4 0.1 3.9 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.6 KXZ48873.1 - 0.066 13.7 0.0 1.6 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXZ48873.1 - 0.16 12.2 0.8 31 4.8 0.3 3.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KXZ48873.1 - 0.24 11.1 0.5 31 4.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain Dynein_C PF18199.1 KXZ48874.1 - 1.8e-39 135.8 0.0 2.1e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain RabGAP-TBC PF00566.18 KXZ48876.1 - 4.3e-38 131.1 0.0 4.5e-37 127.8 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain 2OG-FeII_Oxy_3 PF13640.6 KXZ48876.1 - 6.6e-17 62.2 0.0 2.5e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 KXZ48876.1 - 0.00028 21.3 2.7 0.00078 19.9 2.7 1.7 1 0 0 1 1 1 1 ShK domain-like Peptidase_S66 PF02016.15 KXZ48878.1 - 0.014 15.5 1.4 0.032 14.3 0.1 2.3 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain Taq-exonuc PF09281.10 KXZ48878.1 - 0.077 13.0 0.1 0.077 13.0 0.1 2.8 2 1 1 3 3 3 0 Taq polymerase, exonuclease Lycopene_cycl PF05834.12 KXZ48879.1 - 7.3e-41 140.5 0.0 1.1e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GATA PF00320.27 KXZ48880.1 - 5.3e-15 54.7 2.9 1.1e-14 53.8 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger BAH PF01426.18 KXZ48880.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 BAH domain GATA PF00320.27 KXZ48881.1 - 1e-14 53.8 2.6 1.8e-14 53.0 2.6 1.4 1 0 0 1 1 1 1 GATA zinc finger BAH PF01426.18 KXZ48881.1 - 0.00012 21.9 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 BAH domain OrfB_Zn_ribbon PF07282.11 KXZ48881.1 - 0.21 11.6 1.4 0.4 10.7 1.4 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2_3 PF13878.6 KXZ48881.1 - 0.62 9.9 1.9 4.9 7.1 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO GP38 PF05268.11 KXZ48883.1 - 5.9 6.5 18.9 6.6 6.3 18.9 1.0 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 NPV_P10 PF05531.12 KXZ48884.1 - 0.15 12.6 4.9 3.7 8.1 0.5 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 KXZ48884.1 - 9.1 3.6 43.6 13 3.1 43.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TLC PF03219.14 KXZ48885.1 - 9.8e-18 64.1 0.2 1.2e-17 63.8 0.2 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter TLC PF03219.14 KXZ48886.1 - 3.3e-193 642.9 10.9 4.1e-193 642.6 10.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter OAD_gamma PF04277.13 KXZ48886.1 - 1.1 9.9 4.0 4.1 8.1 0.2 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain MFS_1 PF07690.16 KXZ48886.1 - 8.3 5.2 37.7 0.1 11.5 11.3 3.3 1 1 1 2 2 2 0 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 KXZ48887.1 - 0.044 13.8 1.0 0.044 13.8 1.0 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit SUKH-4 PF14435.6 KXZ48887.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.4 1 1 0 1 1 1 0 SUKH-4 immunity protein PAP1 PF08601.10 KXZ48888.1 - 0.016 15.0 37.0 0.027 14.2 37.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 TFIIA PF03153.13 KXZ48888.1 - 9.8 6.0 32.9 14 5.5 32.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KXZ48889.1 - 4.2e-18 65.7 0.0 5.9e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48889.1 - 4e-12 46.0 0.4 8.5e-07 28.5 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KXZ48889.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ48889.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SNF2_N PF00176.23 KXZ48890.1 - 3.8e-32 111.4 0.0 6.4e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ48890.1 - 3.2e-10 40.3 0.0 8e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HARP PF07443.13 KXZ48890.1 - 2.1e-08 33.7 0.0 5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 HepA-related protein (HARP) DEAD PF00270.29 KXZ48890.1 - 2.2e-07 30.8 0.0 1e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ48890.1 - 1.2e-06 28.7 0.0 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KXZ48890.1 - 0.0068 15.3 0.0 0.023 13.6 0.0 1.8 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 TniB PF05621.11 KXZ48890.1 - 0.01 15.3 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein TPMT PF05724.11 KXZ48890.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) ERCC3_RAD25_C PF16203.5 KXZ48890.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Mg_trans_NIPA PF05653.14 KXZ48891.1 - 3.3e-31 108.5 21.3 4.5e-31 108.1 21.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXZ48891.1 - 0.00076 19.7 0.7 0.00076 19.7 0.7 2.6 2 0 0 2 2 2 1 EamA-like transporter family TBP PF00352.21 KXZ48891.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) Abhydrolase_1 PF00561.20 KXZ48892.1 - 0.0029 17.3 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXZ48892.1 - 0.016 14.7 0.0 0.018 14.5 0.0 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase family PPR_2 PF13041.6 KXZ48893.1 - 3e-50 168.2 0.0 5.5e-08 32.9 0.0 11.3 5 4 7 12 12 12 10 PPR repeat family PPR PF01535.20 KXZ48893.1 - 4.8e-49 161.2 5.0 6.9e-05 22.8 0.0 13.2 13 0 0 13 13 13 10 PPR repeat PPR_3 PF13812.6 KXZ48893.1 - 2.4e-39 133.2 0.0 4.4e-09 36.3 0.0 8.7 6 2 4 11 11 11 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXZ48893.1 - 3.2e-36 122.7 0.0 0.00019 21.0 0.0 9.5 10 0 0 10 10 10 7 PPR repeat PPR_long PF17177.4 KXZ48893.1 - 1.3e-26 93.3 0.2 6.2e-09 35.5 0.0 4.4 3 1 1 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 KXZ48893.1 - 1.9e-05 24.4 0.7 0.49 10.5 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Glu_dehyd_C PF16912.5 KXZ48894.1 - 6.6e-07 29.0 1.7 2.2e-05 24.1 1.7 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 KXZ48894.1 - 5.3e-06 26.4 1.0 8.4e-06 25.8 1.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXZ48894.1 - 0.074 14.1 0.2 0.27 12.3 0.2 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KXZ48894.1 - 0.084 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rieske PF00355.26 KXZ48895.1 - 5.9e-20 71.0 0.0 1.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ48895.1 - 3.9e-17 62.2 0.0 7.1e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase HYR PF02494.16 KXZ48896.1 - 4.4e-23 81.4 34.8 0.00034 20.9 0.4 8.6 7 1 1 8 8 8 6 HYR domain EGF_3 PF12947.7 KXZ48896.1 - 0.00012 22.2 71.6 0.019 15.2 5.8 9.5 9 0 0 9 9 9 7 EGF domain FXa_inhibition PF14670.6 KXZ48896.1 - 0.0077 16.5 6.3 0.0077 16.5 6.3 8.5 7 0 0 7 7 7 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KXZ48896.1 - 0.0096 15.8 3.7 0.0096 15.8 3.7 7.9 8 0 0 8 8 8 5 Complement Clr-like EGF-like RicinB_lectin_2 PF14200.6 KXZ48896.1 - 0.083 13.6 0.1 1.3 9.8 0.1 2.7 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Ank_2 PF12796.7 KXZ48898.1 - 2.1e-72 239.7 15.9 4.9e-21 75.1 1.4 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48898.1 - 3.2e-69 228.5 4.6 1.7e-12 47.6 0.0 8.0 2 1 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48898.1 - 1.1e-55 184.9 27.9 1e-11 44.8 1.9 10.5 1 1 10 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48898.1 - 1.5e-55 183.4 24.6 4.1e-08 33.3 0.0 10.9 11 1 1 12 12 12 9 Ankyrin repeat Ank_3 PF13606.6 KXZ48898.1 - 1.3e-45 148.1 7.3 0.00032 20.9 0.0 10.7 11 0 0 11 11 11 9 Ankyrin repeat PTS_IIA PF02255.16 KXZ48898.1 - 0.076 13.1 9.1 1.8 8.7 0.4 3.8 2 2 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit DOMON PF03351.17 KXZ48899.1 - 5.3e-16 59.0 0.1 7.7e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXZ48899.1 - 1.3e-10 41.5 3.6 2.2e-10 40.8 3.6 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 EptA_B_N PF08019.12 KXZ48899.1 - 0.38 10.6 2.4 0.32 10.9 0.3 1.8 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB Ni_hydr_CYTB PF01292.20 KXZ48899.1 - 2 8.0 10.7 0.21 11.2 5.8 1.8 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 An_peroxidase PF03098.15 KXZ48901.1 - 3e-45 154.8 0.0 3.5e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Acyl-CoA_dh_1 PF00441.24 KXZ48902.1 - 5.7e-19 68.8 6.4 1.1e-18 67.9 6.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXZ48902.1 - 2.8e-08 34.4 3.2 3.9e-08 33.9 0.4 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXZ48902.1 - 5.8e-08 33.1 11.6 5.8e-08 33.1 11.6 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Bacillus_HBL PF05791.11 KXZ48902.1 - 0.07 12.9 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2277 PF10041.9 KXZ48902.1 - 1.4 9.3 5.4 0.5 10.7 1.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Acyl-CoA_dh_1 PF00441.24 KXZ48903.1 - 6.6e-20 71.8 2.5 6.6e-20 71.8 2.5 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KXZ48903.1 - 8.5e-12 45.5 8.2 8.5e-12 45.5 8.2 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXZ48903.1 - 2.8e-10 40.9 0.3 6.8e-10 39.6 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXZ48903.1 - 8.2e-06 25.9 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Pkinase PF00069.25 KXZ48904.1 - 6.1e-39 134.0 0.0 3.4e-36 125.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48904.1 - 2.3e-34 118.9 0.0 1.9e-31 109.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ48904.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ48904.1 - 0.029 13.1 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Na_sulph_symp PF00939.19 KXZ48905.1 - 3.9e-137 458.1 37.8 4.6e-137 457.9 37.8 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXZ48905.1 - 1.1e-10 41.2 49.0 1.3e-10 41.0 47.6 1.7 1 1 1 2 2 2 1 Citrate transporter Nudc_N PF14050.6 KXZ48906.1 - 0.00023 21.1 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Mitofilin PF09731.9 KXZ48906.1 - 3.4 6.4 7.6 4 6.2 7.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIP PF00230.20 KXZ48908.1 - 1.4e-13 51.1 9.3 2.4e-11 43.8 9.3 2.0 1 1 0 1 1 1 1 Major intrinsic protein FA_desaturase PF00487.24 KXZ48910.1 - 4.2e-32 112.0 33.1 4.2e-32 112.0 33.1 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXZ48910.1 - 1.7e-10 41.3 0.0 2.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Bromodomain PF00439.25 KXZ48911.1 - 9e-17 60.9 0.1 1.5e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Bromodomain PEHE PF15275.6 KXZ48911.1 - 2.6e-07 31.3 0.0 2.6e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 PEHE domain TFIIA PF03153.13 KXZ48911.1 - 0.51 10.3 12.0 1.2 9.0 12.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TIMELESS_C PF05029.13 KXZ48911.1 - 1.5 7.9 4.3 2.8 7.0 4.3 1.3 1 0 0 1 1 1 0 Timeless protein C terminal region CDC27 PF09507.10 KXZ48911.1 - 2.3 7.5 14.2 0.06 12.7 7.8 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 KTI12 PF08433.10 KXZ48912.1 - 1.4e-24 87.0 0.0 1.8e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 EDS1_EP PF18117.1 KXZ48914.1 - 0.0023 18.3 0.0 0.0031 18.0 0.0 1.2 1 0 0 1 1 1 1 Enhanced disease susceptibility 1 protein EP domain NifU PF01106.17 KXZ48915.1 - 1.2e-15 57.4 1.6 8.3e-10 38.7 0.5 3.1 2 1 0 2 2 2 2 NifU-like domain TPT PF03151.16 KXZ48916.1 - 1.8e-05 24.2 7.0 2.2e-05 23.9 7.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Sulf_coat_C PF12193.8 KXZ48916.1 - 0.034 14.2 0.2 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Sulfolobus virus coat protein C terminal YopE PF03545.13 KXZ48916.1 - 0.042 14.0 2.4 0.084 13.1 2.4 1.5 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) TauE PF01925.19 KXZ48916.1 - 0.34 10.5 18.1 0.19 11.4 5.0 2.2 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Pkinase PF00069.25 KXZ48919.1 - 1.1e-21 77.4 0.0 1.1e-21 77.4 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KXZ48919.1 - 3.2e-05 23.4 0.0 9.4e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KXZ48919.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC2_membrane PF01061.24 KXZ48921.1 - 4.8e-06 26.1 13.0 6.3e-06 25.7 13.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter Ion_trans PF00520.31 KXZ48921.1 - 0.0044 16.3 4.8 0.024 13.9 5.2 2.0 1 1 1 2 2 2 1 Ion transport protein KdgT PF03812.13 KXZ48921.1 - 0.0082 15.5 1.4 2.5 7.4 0.0 2.2 2 0 0 2 2 2 2 2-keto-3-deoxygluconate permease SNF PF00209.18 KXZ48921.1 - 0.022 13.4 3.4 0.032 12.9 3.4 1.2 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Ank_2 PF12796.7 KXZ48923.1 - 1.9e-25 89.2 0.0 5.9e-16 58.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48923.1 - 1.6e-24 86.0 0.0 5.7e-12 45.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ48923.1 - 5.6e-24 83.9 0.3 2.1e-08 34.3 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ48923.1 - 2.9e-23 81.2 0.0 1.4e-07 31.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KXZ48923.1 - 1.5e-21 74.2 0.0 1.4e-05 25.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Arg_repressor PF01316.21 KXZ48923.1 - 0.01 15.6 0.4 0.64 9.8 0.0 2.8 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain CHAP PF05257.16 KXZ48923.1 - 0.014 16.0 0.6 0.98 10.0 0.0 2.2 1 1 1 2 2 2 0 CHAP domain ScdA_N PF04405.14 KXZ48923.1 - 0.067 12.9 1.2 39 4.0 0.1 3.2 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) Ank_2 PF12796.7 KXZ48924.1 - 1.3e-102 336.5 11.8 5.6e-21 74.9 0.1 5.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ48924.1 - 7.1e-83 269.7 4.2 4.1e-07 30.2 0.0 11.0 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.6 KXZ48924.1 - 6.6e-70 230.3 15.9 1.4e-09 38.0 0.1 10.9 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48924.1 - 2e-62 199.7 0.0 6.2e-06 26.2 0.0 11.1 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 KXZ48924.1 - 1.4e-53 178.6 0.0 6.9e-09 36.1 0.0 6.3 5 1 1 6 6 6 6 Ankyrin repeats (many copies) NifU PF01106.17 KXZ48924.1 - 1.2e-06 28.6 10.1 27 5.0 0.0 8.9 11 0 0 11 11 10 0 NifU-like domain UDPG_MGDP_dh_C PF03720.15 KXZ48924.1 - 4.8e-06 26.9 1.9 7.1 7.1 0.0 6.1 3 3 5 8 8 8 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HTH_15 PF12324.8 KXZ48924.1 - 0.00027 20.8 12.2 2 8.4 0.0 7.7 4 2 5 10 10 10 1 Helix-turn-helix domain of alkylmercury lyase DUF3107 PF11305.8 KXZ48924.1 - 0.0042 17.3 7.6 4.7 7.5 0.1 6.1 1 1 7 9 9 9 1 Protein of unknown function (DUF3107) ArsP_1 PF03773.13 KXZ48924.1 - 0.0055 15.9 0.0 6.4 5.8 0.0 3.8 4 0 0 4 4 4 1 Predicted permease DUF1018 PF06252.12 KXZ48924.1 - 0.0065 17.5 1.7 17 6.5 0.2 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF1018) DUF2016 PF09436.10 KXZ48924.1 - 0.0088 15.8 0.1 10 6.0 0.0 4.8 3 2 3 6 6 6 0 Domain of unknown function (DUF2016) PTS_IIA PF02255.16 KXZ48924.1 - 0.016 15.2 1.1 2.1 8.4 0.4 3.4 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit IF-2 PF11987.8 KXZ48924.1 - 0.033 14.3 11.6 47 4.2 0.0 7.4 1 1 10 11 11 11 0 Translation-initiation factor 2 HEM4 PF02602.15 KXZ48924.1 - 0.044 13.1 3.3 0.23 10.8 0.2 3.1 1 1 4 5 5 5 0 Uroporphyrinogen-III synthase HemD HTH_27 PF13463.6 KXZ48924.1 - 0.091 13.3 10.1 14 6.3 0.1 6.6 4 3 6 10 10 9 0 Winged helix DNA-binding domain PhnA PF03831.14 KXZ48924.1 - 0.88 9.5 16.3 68 3.4 0.1 7.3 6 3 3 9 9 8 0 PhnA domain DUF305 PF03713.13 KXZ48924.1 - 1.4 9.1 4.6 62 3.7 0.1 4.5 4 1 0 6 6 6 0 Domain of unknown function (DUF305) EccE PF11203.8 KXZ48924.1 - 4 7.8 11.0 5 7.5 1.3 4.3 1 1 1 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Pkinase PF00069.25 KXZ48925.1 - 2.8e-16 59.7 0.0 4.7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 KXZ48925.1 - 2.1e-08 34.2 0.1 0.00072 19.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXZ48925.1 - 9.5e-07 29.3 0.0 3.7e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ48925.1 - 2.3e-06 28.0 0.1 1.2e-05 25.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ48925.1 - 7.3e-06 25.9 0.0 0.17 12.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Kdo PF06293.14 KXZ48925.1 - 0.00011 21.7 0.1 0.00021 20.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.6 KXZ48925.1 - 0.0007 19.8 0.5 0.03 14.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KXZ48925.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXZ48925.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.17 KXZ48926.1 - 4.4e-34 118.0 0.0 3.9e-30 105.0 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ48926.1 - 1.1e-25 90.5 0.0 1.2e-21 77.2 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ48926.1 - 0.011 15.1 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ48926.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase WCOR413 PF05562.11 KXZ48926.1 - 0.56 10.1 1.9 22 4.9 0.1 2.3 2 0 0 2 2 2 0 Cold acclimation protein WCOR413 Glyco_hydro_9 PF00759.19 KXZ48927.1 - 4.7e-49 167.9 8.6 1e-23 84.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 9 Pkinase_Tyr PF07714.17 KXZ48928.1 - 0.019 14.3 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KXZ48928.1 - 0.035 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Glyco_hydro_9 PF00759.19 KXZ48929.1 - 2.6e-27 96.3 3.6 3.1e-27 96.0 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KXZ48930.1 - 4e-65 220.8 10.8 4e-65 220.8 10.8 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 Pkinase_Tyr PF07714.17 KXZ48931.1 - 6.3e-25 87.9 0.0 7.8e-18 64.7 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ48931.1 - 5.4e-22 78.4 0.0 4.7e-14 52.4 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ48931.1 - 0.0099 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M11 PF05548.11 KXZ48932.1 - 7.7e-05 22.0 0.0 0.00015 21.1 0.0 1.5 2 0 0 2 2 2 1 Gametolysin peptidase M11 cNMPbd_u2 PF16643.5 KXZ48933.1 - 0.12 12.8 0.2 0.24 11.9 0.2 1.4 1 0 0 1 1 1 0 Unstructured region on cNMP-binding protein Peptidase_S8 PF00082.22 KXZ48934.1 - 3.7e-17 62.5 2.4 7.6e-17 61.5 2.4 1.5 1 0 0 1 1 1 1 Subtilase family SVIP PF15811.5 KXZ48937.1 - 0.03 14.8 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Small VCP/p97-interacting protein PAN_4 PF14295.6 KXZ48938.1 - 0.00045 20.1 0.2 0.00081 19.3 0.2 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXZ48938.1 - 0.0027 17.6 0.8 0.0043 17.0 0.8 1.3 1 0 0 1 1 1 1 PAN domain MANEC PF07502.14 KXZ48938.1 - 0.0042 17.3 0.7 0.006 16.8 0.7 1.3 1 0 0 1 1 1 1 MANEC domain Glyco_transf_34 PF05637.12 KXZ48939.1 - 1.8e-30 106.5 0.1 1.9e-14 54.0 0.0 2.0 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KXZ48939.1 - 0.00013 22.0 0.1 0.00016 21.7 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nsp1_C PF05064.13 KXZ48939.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Glyco_transf_90 PF05686.12 KXZ48940.1 - 2.9e-18 66.0 0.4 4.7e-18 65.3 0.4 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 CSN8_PSD8_EIF3K PF10075.9 KXZ48941.1 - 0.00043 20.3 0.1 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Hyd_WA PF06462.12 KXZ48941.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.6 2 0 0 2 2 2 0 Propeller Arf PF00025.21 KXZ48942.1 - 7.1e-24 84.2 0.2 2e-18 66.5 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 KXZ48942.1 - 1.9e-06 27.6 0.1 0.019 14.6 0.1 2.0 1 1 1 2 2 2 2 Ras family SRPRB PF09439.10 KXZ48942.1 - 0.00041 19.8 0.3 0.77 9.2 0.2 2.2 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KXZ48942.1 - 0.014 15.9 0.0 0.015 15.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KXZ48942.1 - 0.026 14.6 1.4 0.44 10.6 0.6 2.4 2 1 1 3 3 3 0 50S ribosome-binding GTPase Roc PF08477.13 KXZ48942.1 - 0.028 14.6 0.3 0.2 11.9 0.1 2.2 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXZ48942.1 - 0.051 13.5 0.8 7.1 6.5 0.3 2.1 1 1 1 2 2 2 0 RsgA GTPase Neur_chan_memb PF02932.16 KXZ48943.1 - 1.2e-05 25.6 0.1 0.00013 22.1 0.0 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KXZ48943.1 - 0.00021 20.8 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain EutH PF04346.12 KXZ48943.1 - 0.15 11.2 5.5 0.24 10.6 5.5 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH CAP_N PF01213.19 KXZ48944.1 - 1 8.8 3.4 1.9 7.9 3.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_S8 PF00082.22 KXZ48945.1 - 2.5e-14 53.3 1.6 4.8e-14 52.3 1.6 1.4 1 0 0 1 1 1 1 Subtilase family GSH_synth_ATP PF03917.17 KXZ48946.1 - 2.2e-109 365.7 0.0 2.8e-109 365.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KXZ48946.1 - 5.4e-28 97.4 0.0 8.2e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase His_biosynth PF00977.21 KXZ48947.1 - 0.39 10.1 2.1 0.23 10.9 0.1 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein I-EGF_1 PF18372.1 KXZ48949.1 - 7.4 6.8 7.1 0.81 9.8 1.5 2.2 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 Peptidase_S8 PF00082.22 KXZ48951.1 - 1.2e-33 116.7 1.4 1.2e-33 116.7 1.4 2.9 3 0 0 3 3 3 1 Subtilase family Pribosyltran PF00156.27 KXZ48953.1 - 1.1e-25 90.0 0.0 1.3e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KXZ48953.1 - 0.024 14.1 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase PP2C PF00481.21 KXZ48955.1 - 1.2e-40 139.8 0.0 9.6e-35 120.4 0.0 3.0 3 0 0 3 3 3 2 Protein phosphatase 2C Pkinase PF00069.25 KXZ48955.1 - 2.5e-39 135.2 0.0 3.8e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48955.1 - 3.3e-32 111.8 0.0 5.7e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Mac PF12464.8 KXZ48955.1 - 0.031 14.5 0.1 0.088 13.1 0.1 1.7 1 0 0 1 1 1 0 Maltose acetyltransferase Pkinase_fungal PF17667.1 KXZ48955.1 - 0.047 12.5 0.0 0.09 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase MITF_TFEB_C_3_N PF15951.5 KXZ48955.1 - 0.34 11.5 4.3 0.87 10.2 4.3 1.6 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus WD40 PF00400.32 KXZ48956.1 - 3.9e-18 65.5 20.8 0.003 18.4 1.6 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ48956.1 - 5e-07 29.9 0.9 0.094 13.0 0.0 3.5 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CAP_N PF01213.19 KXZ48957.1 - 6.3 6.2 9.7 0.94 8.9 6.0 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sulfotransfer_1 PF00685.27 KXZ48960.1 - 3.9e-09 36.4 0.0 6.3e-08 32.4 0.2 2.0 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ48960.1 - 0.004 17.6 0.0 0.95 9.8 0.1 2.6 2 0 0 2 2 2 2 Sulfotransferase family MRP-L51 PF10244.9 KXZ48960.1 - 0.21 11.8 1.0 33 4.8 0.2 2.7 2 1 0 2 2 2 0 Mitochondrial ribosomal subunit zf-MYND PF01753.18 KXZ48961.1 - 1.2e-07 31.6 8.2 2.3e-07 30.8 8.2 1.5 1 0 0 1 1 1 1 MYND finger DUF3342 PF11822.8 KXZ48962.1 - 1.4e-13 50.8 0.0 1.5e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Phage_integrase PF00589.22 KXZ48964.1 - 4.6e-18 65.6 3.2 1.5e-07 31.4 0.0 3.4 3 0 0 3 3 3 2 Phage integrase family DUF4902 PF16245.5 KXZ48964.1 - 0.067 13.1 0.4 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4902) DUF5049 PF16468.5 KXZ48964.1 - 0.083 12.8 0.3 23 5.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5049) POTRA PF07244.15 KXZ48964.1 - 0.18 12.4 0.4 23 5.6 0.0 2.5 1 1 1 2 2 2 0 Surface antigen variable number repeat DUF2664 PF10867.8 KXZ48964.1 - 0.39 11.2 6.6 2 8.9 6.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) Cytadhesin_P30 PF07271.11 KXZ48964.1 - 1.6 8.2 12.1 10 5.6 0.0 3.0 3 0 0 3 3 3 0 Cytadhesin P30/P32 DUF4574 PF15141.6 KXZ48966.1 - 0.05 13.5 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CDK2AP PF09806.9 KXZ48966.1 - 0.34 11.0 9.3 0.43 10.6 9.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein F-box-like PF12937.7 KXZ48967.1 - 0.00018 21.3 0.0 0.00041 20.2 0.0 1.7 1 1 0 1 1 1 1 F-box-like FAST_1 PF06743.15 KXZ48968.1 - 0.26 11.2 0.2 1.7 8.6 0.1 2.4 3 1 0 3 3 3 0 FAST kinase-like protein, subdomain 1 ATP-synt_ab PF00006.25 KXZ48969.1 - 3.2e-49 167.5 0.1 1.3e-30 106.7 0.0 2.3 1 1 1 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXZ48969.1 - 7.8e-22 77.6 3.1 8.7e-22 77.4 1.3 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KXZ48969.1 - 0.018 14.2 0.8 0.031 13.5 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain RnfC_N PF13375.6 KXZ48969.1 - 0.025 14.5 0.3 0.086 12.8 0.2 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain AAA_16 PF13191.6 KXZ48969.1 - 0.057 13.8 0.6 0.31 11.4 0.1 2.5 3 1 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXZ48969.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 KXZ48969.1 - 0.15 12.4 0.4 0.56 10.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXZ48969.1 - 0.78 9.0 3.6 0.24 10.7 0.4 1.8 2 0 0 2 2 2 0 KaiC Peptidase_C97 PF05903.14 KXZ48970.1 - 3.7e-41 140.4 0.0 4.4e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXZ48970.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Apolipoprotein PF01442.18 KXZ48971.1 - 1.2e-06 28.5 7.5 1.6e-06 28.1 7.5 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3618 PF12277.8 KXZ48971.1 - 7.6e-06 26.1 4.6 0.03 14.6 0.4 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF3618) ApoLp-III PF07464.11 KXZ48971.1 - 0.0027 17.8 2.2 0.0039 17.3 2.2 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Fzo_mitofusin PF04799.13 KXZ48971.1 - 0.0067 16.0 4.8 0.12 11.9 4.8 2.3 1 1 0 1 1 1 1 fzo-like conserved region DUF1664 PF07889.12 KXZ48971.1 - 0.0076 16.3 5.0 0.43 10.6 0.2 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 KXZ48971.1 - 0.0083 16.4 3.3 0.084 13.1 0.7 2.2 1 1 1 2 2 2 1 ABC transporter C-terminal domain DUF4407 PF14362.6 KXZ48971.1 - 0.026 13.9 4.9 0.038 13.4 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TcpS PF17456.2 KXZ48971.1 - 0.032 14.3 0.1 0.07 13.2 0.1 1.5 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S Cluap1 PF10234.9 KXZ48971.1 - 0.047 13.1 3.7 0.058 12.8 3.7 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4795 PF16043.5 KXZ48971.1 - 0.049 13.2 4.2 0.068 12.8 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1690 PF07956.11 KXZ48971.1 - 0.083 13.3 2.7 0.1 13.0 2.7 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) AAL_decarboxy PF03306.13 KXZ48971.1 - 0.091 12.1 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase DUF1640 PF07798.11 KXZ48971.1 - 0.11 12.6 9.7 0.34 10.9 9.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Phasin PF05597.11 KXZ48971.1 - 0.13 12.3 4.7 0.31 11.0 4.7 1.5 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tup_N PF08581.10 KXZ48971.1 - 0.13 12.6 3.2 0.27 11.6 2.7 1.6 1 1 1 2 2 2 0 Tup N-terminal Arm-DNA-bind_5 PF17293.2 KXZ48971.1 - 0.17 12.3 3.2 3.8 8.0 3.1 2.2 1 1 0 1 1 1 0 Arm DNA-binding domain DUF883 PF05957.13 KXZ48971.1 - 0.17 12.5 6.2 0.081 13.5 2.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.15 KXZ48971.1 - 0.18 11.3 5.5 0.23 11.0 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mt_ATP-synt_D PF05873.12 KXZ48971.1 - 0.2 11.5 0.8 0.5 10.2 0.3 1.7 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Phage_Mu_Gam PF07352.12 KXZ48971.1 - 0.21 11.5 2.8 0.35 10.8 1.8 1.7 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein OmpH PF03938.14 KXZ48971.1 - 0.22 11.9 5.2 0.45 10.8 5.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HalX PF08663.10 KXZ48971.1 - 0.22 11.9 6.3 2.7 8.4 0.4 3.0 1 1 1 2 2 2 0 HalX domain DUF1993 PF09351.10 KXZ48971.1 - 0.22 11.6 0.9 0.43 10.7 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) SpoOE-like PF09388.10 KXZ48971.1 - 0.23 11.4 2.6 5 7.1 0.1 3.3 1 1 2 3 3 3 0 Spo0E like sporulation regulatory protein Vps51 PF08700.11 KXZ48971.1 - 0.52 10.4 5.4 4.3 7.5 5.0 2.6 1 1 1 2 2 2 0 Vps51/Vps67 HSCB_C PF07743.13 KXZ48971.1 - 0.52 10.8 5.1 1.5 9.4 2.0 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Nnf1 PF03980.14 KXZ48971.1 - 0.64 10.4 7.7 13 6.2 0.4 2.4 1 1 1 2 2 2 0 Nnf1 YlqD PF11068.8 KXZ48971.1 - 0.68 10.3 5.6 1.8 8.9 5.6 1.8 1 1 0 1 1 1 0 YlqD protein HSBP1 PF06825.12 KXZ48971.1 - 1.2 9.1 8.6 0.17 11.8 1.5 2.7 2 1 1 3 3 3 0 Heat shock factor binding protein 1 zf-His_Me_endon PF05551.11 KXZ48972.1 - 0.00081 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease gpUL132 PF11359.8 KXZ48972.1 - 0.037 13.6 0.2 0.053 13.1 0.2 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 VOMI PF03762.17 KXZ48975.1 - 1.2e-36 126.4 4.1 3.8e-32 111.8 2.5 2.2 2 0 0 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) EF-hand_1 PF00036.32 KXZ48976.1 - 0.001 18.4 0.1 0.0033 16.9 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ48976.1 - 0.0018 17.7 0.9 0.0096 15.4 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXZ48976.1 - 0.0074 16.1 0.0 0.026 14.5 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXZ48976.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 KXZ48976.1 - 0.19 12.2 0.0 0.42 11.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Cupin_1 PF00190.22 KXZ48977.1 - 0.18 11.4 0.0 9.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Cupin VOMI PF03762.17 KXZ48978.1 - 4.1e-34 118.2 3.9 1.6e-30 106.5 1.5 2.5 2 1 0 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) DUF2671 PF10877.8 KXZ48978.1 - 0.022 14.5 0.2 15 5.4 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2671) PHD PF00628.29 KXZ48980.1 - 7.2e-06 25.8 1.0 1.5e-05 24.8 1.0 1.6 1 0 0 1 1 1 1 PHD-finger VOMI PF03762.17 KXZ48982.1 - 5.9e-27 94.9 0.7 4.5e-25 88.7 0.4 2.0 2 0 0 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) EF-hand_1 PF00036.32 KXZ48983.1 - 4.2e-05 22.8 0.1 9.4e-05 21.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ48983.1 - 0.0015 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ48983.1 - 0.0039 17.0 0.1 0.0091 15.9 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXZ48983.1 - 0.0046 16.4 0.0 0.0087 15.5 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ48983.1 - 0.0093 16.4 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair VOMI PF03762.17 KXZ48984.1 - 1.4e-29 103.4 7.5 2e-28 99.7 2.9 2.7 2 1 1 3 3 3 2 Vitelline membrane outer layer protein I (VOMI) EF-hand_1 PF00036.32 KXZ48984.1 - 3.9e-05 22.9 0.2 8.4e-05 21.9 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ48984.1 - 0.0012 18.2 0.1 0.0028 17.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ48984.1 - 0.0017 18.1 0.1 0.0046 16.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ48984.1 - 0.0032 17.9 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ48984.1 - 0.0057 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair GCSF PF16647.5 KXZ48984.1 - 0.14 12.0 0.1 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 Granulocyte colony-stimulating factor VOMI PF03762.17 KXZ48985.1 - 1.6e-27 96.7 9.6 5.3e-26 91.8 7.1 2.4 1 1 0 2 2 2 1 Vitelline membrane outer layer protein I (VOMI) EF-hand_1 PF00036.32 KXZ48985.1 - 0.001 18.5 0.1 0.002 17.6 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ48985.1 - 0.0062 17.0 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ48985.1 - 0.0084 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ48985.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ48985.1 - 0.019 14.9 0.1 0.045 13.7 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain HCBP_related PF06594.11 KXZ48985.1 - 0.44 10.5 3.1 19 5.3 0.0 3.6 4 0 0 4 4 4 0 Haemolysin-type calcium binding protein related domain THF_DHG_CYH PF00763.23 KXZ48986.1 - 2.5e-36 124.5 0.1 5.4e-36 123.4 0.1 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KXZ48986.1 - 1.8e-35 121.6 0.6 9.3e-35 119.3 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 KXZ48986.1 - 0.0016 17.5 0.2 0.0029 16.6 0.2 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family BRE1 PF08647.11 KXZ48987.1 - 6.2e-06 26.2 20.7 8.1e-06 25.8 0.1 4.3 3 2 0 4 4 4 2 BRE1 E3 ubiquitin ligase CEP63 PF17045.5 KXZ48987.1 - 3.3e-05 23.9 14.1 3.3e-05 23.9 14.1 2.3 1 1 1 2 2 2 1 Centrosomal protein of 63 kDa ATG16 PF08614.11 KXZ48987.1 - 3.9e-05 24.0 34.1 0.00023 21.4 6.8 3.4 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KXZ48987.1 - 0.00022 21.0 3.6 0.00022 21.0 3.6 3.2 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 KXZ48987.1 - 0.0069 16.4 2.4 0.0069 16.4 2.4 4.2 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI3K_P85_iSH2 PF16454.5 KXZ48987.1 - 0.008 15.8 17.0 0.83 9.2 4.2 4.5 2 1 2 4 4 4 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AKNA PF12443.8 KXZ48987.1 - 0.027 15.1 0.2 0.1 13.3 0.2 2.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor CENP-H PF05837.12 KXZ48987.1 - 0.031 14.7 30.6 0.073 13.5 2.2 4.1 2 2 1 4 4 4 0 Centromere protein H (CENP-H) ECM11 PF15463.6 KXZ48987.1 - 0.033 14.8 0.9 0.033 14.8 0.9 2.3 2 0 0 2 2 2 0 Extracellular mutant protein 11 BLUF PF04940.12 KXZ48987.1 - 0.038 14.1 2.6 11 6.3 0.0 3.5 4 1 0 4 4 4 0 Sensors of blue-light using FAD Fez1 PF06818.15 KXZ48987.1 - 0.1 13.0 25.3 2.6 8.4 13.1 3.2 1 1 1 2 2 2 0 Fez1 UPF0242 PF06785.11 KXZ48987.1 - 0.19 11.8 27.1 0.45 10.6 1.5 3.4 2 1 2 4 4 3 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KXZ48987.1 - 0.51 10.4 26.6 0.89 9.6 0.5 4.3 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KXZ48987.1 - 0.59 10.2 15.4 0.85 9.7 2.6 4.6 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KXZ48987.1 - 2.8 8.4 15.1 3.6 8.1 0.4 5.8 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 KXZ48987.1 - 6.9 7.2 14.5 13 6.4 1.7 4.2 1 1 3 4 4 4 0 Protein of unknown function DUF16 HIT PF01230.23 KXZ48989.1 - 0.00074 20.2 0.2 0.0015 19.2 0.2 1.6 1 0 0 1 1 1 1 HIT domain BTB PF00651.31 KXZ48990.1 - 5.2e-13 49.2 0.0 8e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain SBP PF03110.14 KXZ48991.1 - 4.4e-20 71.8 3.0 6.6e-20 71.2 3.0 1.2 1 0 0 1 1 1 1 SBP domain PRIMA1 PF16101.5 KXZ48991.1 - 4.8 7.2 4.7 9.3 6.3 4.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Sporozoite_P67 PF05642.11 KXZ48992.1 - 1.5 6.8 4.5 1.7 6.6 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Phytase-like PF13449.6 KXZ48993.1 - 0.063 13.2 0.0 0.64 9.9 0.0 2.0 1 1 0 1 1 1 0 Esterase-like activity of phytase TLC PF03219.14 KXZ48994.1 - 9.8e-118 394.0 0.1 4e-60 204.0 0.1 2.0 2 0 0 2 2 2 2 TLC ATP/ADP transporter Peptidase_M76 PF09768.9 KXZ48995.1 - 9.9e-24 84.0 0.0 6e-20 71.7 0.0 2.0 2 0 0 2 2 2 2 Peptidase M76 family DUF2268 PF10026.9 KXZ48995.1 - 0.22 11.1 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Pkinase PF00069.25 KXZ48996.1 - 5.2e-54 183.4 0.0 8e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ48996.1 - 5.4e-29 101.3 0.0 2.5e-28 99.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXZ48996.1 - 0.0067 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXZ48996.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KXZ48996.1 - 0.016 15.2 0.0 0.016 15.2 0.0 3.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family TFIIA PF03153.13 KXZ48996.1 - 1.6 8.7 12.1 0.15 12.1 4.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXZ48996.1 - 5.9 6.4 10.3 9 5.8 10.3 1.1 1 0 0 1 1 1 0 Spt20 family zf-Nse PF11789.8 KXZ48997.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KXZ48997.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF1380 PF07128.12 KXZ48997.1 - 0.12 12.5 0.2 0.36 11.0 0.1 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1380) U-box PF04564.15 KXZ48997.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain Speriolin_C PF15059.6 KXZ48997.1 - 0.19 11.8 0.0 2.2 8.4 0.0 2.1 1 1 1 2 2 2 0 Speriolin C-terminus TT_ORF2 PF02957.15 KXZ48997.1 - 0.42 11.6 6.1 8.1 7.4 3.8 2.5 2 1 0 2 2 2 0 TT viral ORF2 mTERF PF02536.14 KXZ48999.1 - 0.045 12.7 0.0 0.53 9.2 0.0 2.2 2 0 0 2 2 2 0 mTERF Pkinase_Tyr PF07714.17 KXZ49000.1 - 2.1e-30 105.9 0.0 6.8e-29 100.9 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49000.1 - 1.7e-25 89.9 0.0 1.3e-21 77.2 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49000.1 - 1e-05 24.5 0.0 1.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49000.1 - 0.0034 17.3 1.4 0.02 14.8 0.2 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family TPR_12 PF13424.6 KXZ49001.1 - 4.1e-62 206.4 53.5 1.6e-15 57.2 8.7 4.0 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ49001.1 - 4.6e-52 172.6 29.0 1.7e-12 46.8 1.7 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ49001.1 - 6.1e-22 76.0 18.2 1.7e-05 24.5 0.8 5.5 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ49001.1 - 2.1e-14 52.6 10.6 0.0067 16.2 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ49001.1 - 1.8e-12 47.7 35.3 6.5e-05 23.5 12.4 5.1 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ49001.1 - 2.2e-12 46.1 19.1 0.005 16.8 1.4 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ49001.1 - 3.6e-12 45.7 36.3 0.0036 17.8 1.2 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ49001.1 - 2.4e-10 40.3 29.4 0.021 15.6 3.3 5.4 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ49001.1 - 9.1e-10 38.0 5.9 0.034 14.4 0.3 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ49001.1 - 4.7e-09 36.6 13.5 0.00049 20.6 0.6 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ49001.1 - 5.8e-08 32.5 9.6 1.2e-07 31.4 7.5 2.0 1 1 1 2 2 2 2 MalT-like TPR region TPR_17 PF13431.6 KXZ49001.1 - 4.6e-05 23.5 8.2 2.9 8.5 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ49001.1 - 8.3e-05 22.7 0.3 0.52 10.6 0.0 3.6 2 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 KXZ49001.1 - 0.0029 17.8 14.3 0.065 13.5 4.1 3.3 2 1 1 3 3 3 2 Tetratrico peptide repeat Atu4866 PF11512.8 KXZ49001.1 - 0.0032 17.8 4.5 6.6 7.2 0.1 4.3 5 0 0 5 5 5 1 Agrobacterium tumefaciens protein Atu4866 TPR_3 PF07720.12 KXZ49001.1 - 0.071 13.1 1.1 39 4.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1449 PF07290.11 KXZ49001.1 - 0.15 11.7 0.6 4.2 6.9 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1449) PPR PF01535.20 KXZ49001.1 - 0.46 10.8 1.4 1.1e+02 3.4 0.0 3.8 5 0 0 5 5 4 0 PPR repeat TPR_6 PF13174.6 KXZ49001.1 - 4.2 8.2 8.6 12 6.8 1.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ49001.1 - 6.1 6.6 12.7 1.1 9.0 0.3 4.4 5 0 0 5 5 5 0 TPR repeat Wzy_C_2 PF11846.8 KXZ49001.1 - 7 6.5 8.8 28 4.6 0.2 3.9 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 KXZ49002.1 - 2.8e-05 24.3 1.0 7.5e-05 22.9 1.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ49002.1 - 0.015 15.1 1.9 0.048 13.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ49003.1 - 4.4e-14 51.8 8.6 1.4e-10 40.7 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ49003.1 - 1.1e-13 51.2 1.3 3.4e-13 49.7 1.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ49003.1 - 5.7e-06 25.9 0.3 0.00046 19.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ49003.1 - 0.00027 20.8 1.0 0.0007 19.5 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ49003.1 - 0.00043 20.9 1.4 0.0029 18.3 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ49003.1 - 0.00055 19.8 2.2 0.00082 19.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ49003.1 - 0.0017 18.8 0.6 0.0017 18.8 0.6 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ49003.1 - 0.0018 18.3 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ49003.1 - 0.31 11.6 2.9 0.34 11.4 0.8 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat p25-alpha PF05517.12 KXZ49004.1 - 3.4e-42 144.2 0.0 1.8e-27 96.4 0.0 2.2 2 0 0 2 2 2 2 p25-alpha EF-hand_7 PF13499.6 KXZ49004.1 - 2.9e-08 34.0 0.1 5e-06 26.9 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ49004.1 - 1.8e-07 30.5 0.0 0.01 15.7 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KXZ49004.1 - 1.1e-06 27.7 0.0 0.00017 20.9 0.0 3.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXZ49004.1 - 3.4e-05 23.2 0.0 0.00025 20.4 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXZ49004.1 - 0.00095 19.0 0.0 0.083 12.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair Paf67 PF10255.9 KXZ49005.1 - 9.7e-130 433.2 0.0 1.3e-129 432.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 RPAP1_N PF08621.10 KXZ49005.1 - 0.11 12.2 0.6 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal AF-4 PF05110.13 KXZ49006.1 - 1.5 6.8 11.6 2.5 6.1 11.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_C1 PF00112.23 KXZ49007.1 - 8.6e-66 222.1 2.9 1.1e-65 221.7 2.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease LysM PF01476.20 KXZ49007.1 - 5.9e-47 157.5 7.0 7.6e-13 48.3 0.2 5.1 6 0 0 6 6 6 4 LysM domain Inhibitor_I29 PF08246.12 KXZ49007.1 - 4.5e-10 39.8 0.3 7.2e-10 39.2 0.3 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KXZ49007.1 - 0.041 12.7 2.9 1.3 7.7 0.4 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_M11 PF05548.11 KXZ49008.1 - 0.00024 20.3 0.0 0.00024 20.3 0.0 1.0 1 0 0 1 1 1 1 Gametolysin peptidase M11 Dynein_C PF18199.1 KXZ49009.1 - 1.4e-77 260.9 0.0 2e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KXZ49009.1 - 3.1e-56 189.7 0.0 4.6e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXZ49009.1 - 1.5e-45 154.2 0.0 3.3e-45 153.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain FAST_1 PF06743.15 KXZ49010.1 - 7.2e-05 22.7 0.0 0.18 11.7 0.0 4.2 4 1 1 5 5 5 2 FAST kinase-like protein, subdomain 1 RRM_1 PF00076.22 KXZ49011.1 - 6e-14 51.6 0.0 2e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_6 PF12774.7 KXZ49012.1 - 1.2e-162 540.4 0.0 3.1e-161 535.8 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ49012.1 - 9.8e-130 433.2 1.3 9.8e-130 433.2 1.3 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXZ49012.1 - 2e-106 355.7 0.0 3.8e-105 351.5 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KXZ49012.1 - 1.2e-105 352.5 0.0 2.5e-105 351.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXZ49012.1 - 3.8e-93 310.7 0.0 4.8e-92 307.1 0.0 2.8 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ49012.1 - 8.5e-75 250.2 0.3 1.6e-70 236.3 0.0 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ49012.1 - 1e-57 194.5 0.0 3.3e-57 192.8 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXZ49012.1 - 5.2e-54 183.6 10.7 5.2e-54 183.6 10.7 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXZ49012.1 - 8.2e-46 155.0 0.0 6.4e-44 148.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXZ49012.1 - 3.6e-23 82.0 0.0 1.1e-22 80.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ49012.1 - 5.6e-20 71.4 0.0 2.2e-19 69.5 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ49012.1 - 4.5e-13 49.4 0.2 0.00097 19.1 0.0 6.5 6 1 0 6 6 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 KXZ49012.1 - 1.5e-07 31.9 1.8 0.33 11.4 0.0 5.4 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ49012.1 - 8.1e-07 29.4 0.1 7.8 6.8 0.0 5.5 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 KXZ49012.1 - 8.7e-07 29.5 0.4 0.028 15.0 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KXZ49012.1 - 4e-06 27.3 13.7 0.13 12.6 0.0 7.0 6 0 0 6 6 5 2 AAA ATPase domain T2SSE PF00437.20 KXZ49012.1 - 7.9e-06 25.1 0.2 0.028 13.5 0.0 4.1 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXZ49012.1 - 0.0025 17.5 0.1 7.5 6.4 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain THP2 PF09432.10 KXZ49012.1 - 0.0033 17.5 0.7 0.14 12.2 0.0 3.4 2 0 0 2 2 2 1 Tho complex subunit THP2 Sigma54_activat PF00158.26 KXZ49012.1 - 0.018 14.7 0.0 1 9.0 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain TsaE PF02367.17 KXZ49012.1 - 0.079 13.0 3.8 5.6 7.0 0.1 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Spc7 PF08317.11 KXZ49012.1 - 0.094 11.6 30.3 0.16 10.8 3.5 5.0 5 0 0 5 5 5 0 Spc7 kinetochore protein RNA_helicase PF00910.22 KXZ49012.1 - 0.14 12.6 0.1 91 3.5 0.0 4.0 4 0 0 4 4 4 0 RNA helicase Imm71 PF15602.6 KXZ49012.1 - 0.22 11.6 7.0 0.41 10.7 0.2 3.5 3 0 0 3 3 3 0 Immunity protein 71 ResIII PF04851.15 KXZ49012.1 - 0.54 10.2 3.0 9.6 6.2 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit UPF0181 PF03701.14 KXZ49013.1 - 0.43 10.2 6.1 1.3 8.7 6.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) DUF4239 PF14023.6 KXZ49013.1 - 0.98 9.1 3.9 4.2 7.0 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) EzrA PF06160.12 KXZ49013.1 - 1.5 6.9 19.1 2.3 6.3 17.9 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA IFT20 PF14931.6 KXZ49013.1 - 2.8 8.1 15.7 2.6 8.2 8.6 2.6 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Apt1 PF10351.9 KXZ49013.1 - 4.3 6.1 7.5 7.2 5.3 7.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Atg14 PF10186.9 KXZ49013.1 - 4.6 6.2 21.6 9.9 5.1 0.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FPP PF05911.11 KXZ49013.1 - 4.9 5.2 23.7 0.87 7.7 19.2 1.7 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Vps51 PF08700.11 KXZ49014.1 - 5.2e-13 48.9 1.1 1.3e-12 47.6 1.1 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KXZ49014.1 - 3.5e-07 29.2 0.8 6.1e-07 28.4 0.8 1.3 1 0 0 1 1 1 1 Dor1-like family PAR1 PF06521.11 KXZ49014.1 - 0.26 10.9 0.7 0.57 9.8 0.7 1.5 1 0 0 1 1 1 0 PAR1 protein tRNA_Me_trans PF03054.16 KXZ49015.1 - 1.7e-17 63.3 0.1 7.1e-10 38.2 0.0 3.0 2 1 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.21 KXZ49015.1 - 0.024 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Pkinase_Tyr PF07714.17 KXZ49016.1 - 9.3e-29 100.5 0.0 9.9e-26 90.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49016.1 - 2.8e-28 99.0 0.0 2.4e-26 92.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ49016.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 KXZ49017.1 - 8e-48 162.5 0.0 1.3e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Proteasome PF00227.26 KXZ49018.1 - 4e-18 65.6 0.0 1.1e-17 64.1 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit tRNA_SAD PF07973.14 KXZ49019.1 - 2.2e-09 37.3 0.2 4.1e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KXZ49019.1 - 0.0021 16.7 0.0 0.0028 16.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 KXZ49019.1 - 2.6 8.5 5.9 0.67 10.4 2.1 2.0 2 0 0 2 2 2 0 DHHA1 domain Pro_isomerase PF00160.21 KXZ49020.1 - 8.1e-05 22.9 0.0 0.00019 21.8 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADH_N PF08240.12 KXZ49021.1 - 3.6e-25 88.0 3.9 7.2e-25 87.0 3.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXZ49021.1 - 3.7e-19 69.0 0.3 8.6e-19 67.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXZ49021.1 - 1.7e-07 32.3 0.1 3.1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXZ49021.1 - 2.8e-06 26.8 0.1 4.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IGFBP PF00219.18 KXZ49021.1 - 0.0024 18.5 2.4 0.0047 17.5 2.4 1.4 1 0 0 1 1 1 1 Insulin-like growth factor binding protein 2-Hacid_dh_C PF02826.19 KXZ49021.1 - 0.0035 16.7 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KXZ49022.1 - 5.5e-05 22.7 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ49022.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXZ49023.1 - 3.2e-26 92.0 0.1 2.4e-25 89.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ49023.1 - 4.2e-21 75.6 0.1 2.4e-20 73.1 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RWP-RK PF02042.15 KXZ49024.1 - 2.4e-19 69.0 0.2 5.3e-19 67.9 0.2 1.6 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 KXZ49024.1 - 0.093 12.4 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 BCNT PF07572.12 KXZ49025.1 - 1.2e-21 76.6 2.1 1.4e-21 76.3 2.1 1.0 1 0 0 1 1 1 1 Bucentaur or craniofacial development CENP-B_dimeris PF09026.10 KXZ49026.1 - 7.3 7.0 14.0 16 5.9 1.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain APG6_N PF17675.1 KXZ49027.1 - 0.0092 16.5 1.5 0.0092 16.5 1.5 2.3 2 0 0 2 2 2 1 Apg6 coiled-coil region TmoB PF06234.12 KXZ49027.1 - 0.019 15.0 0.1 0.067 13.3 0.1 1.9 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) CCDC144C PF14915.6 KXZ49027.1 - 0.52 9.4 3.9 1.1 8.3 3.9 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region KASH_CCD PF14662.6 KXZ49027.1 - 4.6 7.0 5.5 5.8 6.7 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.6 KXZ49027.1 - 5.8 6.9 6.0 2.9 7.9 0.4 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion BACK PF07707.15 KXZ49028.1 - 5.8e-09 36.0 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ49028.1 - 0.24 11.6 0.0 7.7 6.8 0.0 2.8 3 0 0 3 3 3 0 BTB/POZ domain Exo_endo_phos PF03372.23 KXZ49029.1 - 4.7e-15 55.7 2.1 4.8e-12 45.9 0.3 3.8 2 2 1 3 3 3 2 Endonuclease/Exonuclease/phosphatase family Lipase_3 PF01764.25 KXZ49030.1 - 8.4e-08 32.2 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KXZ49030.1 - 0.24 11.1 0.0 0.95 9.1 0.1 1.9 2 0 0 2 2 2 0 PGAP1-like protein MORN PF02493.20 KXZ49031.1 - 4.3e-37 123.8 48.8 7.3e-07 28.7 1.2 8.9 9 0 0 9 9 9 8 MORN repeat MFS_1 PF07690.16 KXZ49035.1 - 9.8e-37 126.7 39.3 2.5e-36 125.3 33.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily HYR PF02494.16 KXZ49036.1 - 6.1e-09 36.1 18.5 0.0021 18.4 1.1 6.0 6 0 0 6 6 6 3 HYR domain RicinB_lectin_2 PF14200.6 KXZ49036.1 - 0.012 16.3 0.1 0.15 12.8 0.0 2.5 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like cEGF PF12662.7 KXZ49036.1 - 2.2 8.3 5.9 1.1 9.3 2.4 2.4 2 0 0 2 2 2 0 Complement Clr-like EGF-like RED_N PF07808.13 KXZ49037.1 - 1.5e-56 191.6 0.0 2.8e-56 190.7 0.0 1.4 1 0 0 1 1 1 1 RED-like protein N-terminal region RED_C PF07807.11 KXZ49037.1 - 7.6e-29 100.5 1.1 7.6e-29 100.5 1.1 2.5 2 0 0 2 2 2 1 RED-like protein C-terminal region SUV3_C PF12513.8 KXZ49038.1 - 3.3e-13 49.3 0.2 4.6e-13 48.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal RepA_C PF04796.12 KXZ49038.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Plasmid encoded RepA protein RED_N PF07808.13 KXZ49042.1 - 2.6e-64 217.0 0.2 4.7e-64 216.2 0.2 1.4 1 0 0 1 1 1 1 RED-like protein N-terminal region RED_C PF07807.11 KXZ49042.1 - 1.4e-36 125.3 1.9 1.4e-36 125.3 1.9 2.6 2 0 0 2 2 2 1 RED-like protein C-terminal region Ank_2 PF12796.7 KXZ49043.1 - 1.5e-11 44.7 1.2 0.031 14.8 0.5 5.6 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49043.1 - 2.1e-08 34.5 5.3 24 5.6 0.1 8.0 6 2 2 8 8 8 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ49043.1 - 6.8e-05 23.1 11.5 0.032 14.6 0.3 6.0 6 3 3 9 9 9 2 Ankyrin repeats (many copies) DUF434 PF04256.12 KXZ49043.1 - 0.069 12.8 0.6 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF434) HTH_39 PF14090.6 KXZ49043.1 - 0.13 12.0 0.0 3.8 7.3 0.0 3.2 3 1 1 4 4 4 0 Helix-turn-helix domain ATX_III PF08098.11 KXZ49043.1 - 1.1 9.3 5.3 2.8 8.1 0.3 3.7 4 0 0 4 4 4 0 Anemonia sulcata toxin III family DDE_Tnp_ISL3 PF01610.17 KXZ49044.1 - 0.15 11.8 5.7 0.22 11.2 5.7 1.1 1 0 0 1 1 1 0 Transposase DUF2358 PF10184.9 KXZ49046.1 - 8.6e-10 38.9 0.0 1.1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KXZ49046.1 - 2.5e-08 34.5 0.0 3.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXZ49046.1 - 0.067 13.6 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF4336 PF14234.6 KXZ49047.1 - 8.5e-20 71.2 0.0 5.4e-14 52.1 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) F-box-like PF12937.7 KXZ49048.1 - 8.2e-10 38.4 0.4 9.4e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXZ49048.1 - 0.0012 18.6 0.4 0.0046 16.8 0.0 1.9 2 0 0 2 2 2 1 F-box domain Prok-TraM PF09228.10 KXZ49048.1 - 0.052 13.9 0.1 0.61 10.5 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Elongin_A PF06881.11 KXZ49048.1 - 0.061 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Sld5 PF05916.11 KXZ49048.1 - 0.075 13.5 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 GINS complex protein ACOX PF01756.19 KXZ49049.1 - 4.9e-35 120.7 0.0 1.8e-33 115.6 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXZ49049.1 - 1.9e-25 89.8 0.0 3.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KXZ49049.1 - 2.5e-13 50.0 0.1 3.7e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXZ49049.1 - 0.00017 21.8 0.8 0.00059 20.1 0.8 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PseudoU_synth_2 PF00849.22 KXZ49051.1 - 2e-17 63.7 0.0 6.8e-08 32.8 0.0 3.3 2 2 0 2 2 2 2 RNA pseudouridylate synthase DUF4200 PF13863.6 KXZ49053.1 - 4.8e-31 107.6 38.7 1.2e-29 103.1 27.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 KXZ49053.1 - 0.022 15.0 4.3 0.022 15.0 4.3 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4279 PF14106.6 KXZ49053.1 - 0.098 12.9 2.9 0.18 12.0 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Lip_prot_lig_C PF10437.9 KXZ49053.1 - 0.17 11.9 2.6 0.22 11.5 0.7 2.1 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus RP-C_C PF11800.8 KXZ49053.1 - 4.6 7.3 13.2 2.5e+02 1.6 13.2 2.3 1 1 0 1 1 1 0 Replication protein C C-terminal region Peptidase_C15 PF01470.17 KXZ49054.1 - 9e-10 39.1 0.0 1.2e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Atg8 PF02991.16 KXZ49055.1 - 4.6e-51 171.3 0.3 5.3e-51 171.1 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KXZ49055.1 - 5e-06 26.8 0.0 6.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 2-Hacid_dh_C PF02826.19 KXZ49056.1 - 2.1e-53 180.3 0.0 3e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KXZ49056.1 - 0.0014 18.6 0.3 0.0041 17.0 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding 2-Hacid_dh PF00389.30 KXZ49056.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 KXZ49056.1 - 0.0022 18.5 0.1 0.0049 17.4 0.1 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_2 PF03446.15 KXZ49056.1 - 0.0024 18.0 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KXZ49056.1 - 0.0088 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KXZ49056.1 - 0.011 15.8 0.1 0.021 14.9 0.1 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 KXZ49056.1 - 0.025 15.2 0.0 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXZ49056.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Alg6_Alg8 PF03155.15 KXZ49057.1 - 4.3e-83 279.9 0.0 1.1e-49 169.7 0.0 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF1427 PF07235.11 KXZ49057.1 - 0.075 13.0 1.9 0.099 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) DUF773 PF05600.12 KXZ49058.1 - 0.043 12.6 0.5 0.052 12.3 0.5 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Use1 PF09753.9 KXZ49058.1 - 0.057 13.1 1.2 0.091 12.5 1.2 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 FlpD PF02662.16 KXZ49058.1 - 0.37 10.8 2.5 0.66 10.0 0.0 2.5 3 0 0 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit rve PF00665.26 KXZ49059.1 - 2e-17 63.5 0.0 2.6e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KXZ49059.1 - 0.00075 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain TTRAP PF14203.6 KXZ49060.1 - 0.12 12.4 0.1 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein CheB_methylest PF01339.17 KXZ49060.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 CheB methylesterase zf-MYND PF01753.18 KXZ49061.1 - 1.4e-07 31.5 11.4 1.4e-07 31.5 11.4 3.1 4 0 0 4 4 4 1 MYND finger Pkinase PF00069.25 KXZ49062.1 - 1.5e-76 257.3 0.0 2.5e-76 256.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49062.1 - 1.3e-33 116.4 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 KXZ49062.1 - 7.8e-30 100.2 10.8 9.6e-08 31.1 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ49062.1 - 3.6e-23 81.8 6.4 6.8e-11 42.5 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ49062.1 - 1.7e-22 77.4 8.4 1.2e-06 28.0 0.2 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXZ49062.1 - 1.7e-18 65.2 5.0 7.4e-05 22.1 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXZ49062.1 - 9.1e-16 57.5 7.6 1.2e-07 31.5 0.6 3.8 1 1 3 4 4 4 4 EF-hand domain pair Kinase-like PF14531.6 KXZ49062.1 - 3.9e-08 33.0 0.1 8.1e-05 22.1 0.0 3.2 2 1 0 3 3 3 2 Kinase-like EF-hand_4 PF12763.7 KXZ49062.1 - 6e-07 29.4 2.2 0.00044 20.2 0.3 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXZ49062.1 - 9.9e-06 25.8 1.3 0.046 14.0 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KXZ49062.1 - 0.00017 21.9 0.4 0.058 13.7 0.2 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 KXZ49062.1 - 0.0034 16.8 0.1 0.007 15.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EFhand_Ca_insen PF08726.10 KXZ49062.1 - 0.0046 17.0 0.3 2.3 8.4 0.0 2.9 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KXZ49062.1 - 0.0046 17.8 0.2 4.9 8.1 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain APH PF01636.23 KXZ49062.1 - 0.0051 16.8 0.0 1.2 9.0 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Caleosin PF05042.13 KXZ49062.1 - 0.024 14.6 0.2 6.1 6.7 0.1 2.8 2 1 1 3 3 3 0 Caleosin related protein Pilus_CpaD PF09476.10 KXZ49062.1 - 0.14 11.9 0.2 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) zf-MYND PF01753.18 KXZ49063.1 - 1e-06 28.7 9.4 3.2e-06 27.1 9.4 1.9 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.25 KXZ49067.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ49067.1 - 0.0032 16.9 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.31 KXZ49068.1 - 8.3e-18 64.3 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain SNARE_assoc PF09335.11 KXZ49069.1 - 1.2e-19 70.9 1.6 1.2e-19 70.9 1.6 2.3 2 1 0 2 2 2 1 SNARE associated Golgi protein Herpes_capsid PF06112.11 KXZ49069.1 - 2.9 7.9 6.8 5.7 7.0 6.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein 60KD_IMP PF02096.20 KXZ49070.1 - 8.1e-13 48.6 0.1 4.7e-12 46.1 0.1 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein LrgA PF03788.14 KXZ49070.1 - 0.0004 20.3 0.4 0.00092 19.1 0.4 1.5 1 0 0 1 1 1 1 LrgA family DUF4300 PF14133.6 KXZ49070.1 - 0.21 11.3 0.1 0.87 9.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4300) PRT_C PF08372.10 KXZ49071.1 - 3.4e-16 59.4 0.1 7.5e-16 58.3 0.0 1.5 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal C2 PF00168.30 KXZ49071.1 - 0.0028 17.9 0.0 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 C2 domain Cyto_heme_lyase PF01265.17 KXZ49072.1 - 9.4e-54 183.0 2.6 5.6e-53 180.4 2.6 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ank_4 PF13637.6 KXZ49073.1 - 1.1e-09 38.7 2.1 2.5 8.8 1.4 5.3 2 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49073.1 - 2.3e-07 31.3 0.0 0.0016 18.9 0.5 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ49073.1 - 4.5e-06 26.6 0.1 5.1 8.0 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat FAD_binding_2 PF00890.24 KXZ49073.1 - 0.046 12.8 2.6 0.91 8.5 0.0 2.4 2 1 1 3 3 3 0 FAD binding domain Ank_5 PF13857.6 KXZ49073.1 - 0.075 13.4 1.3 11 6.5 0.2 3.9 2 1 2 4 4 4 0 Ankyrin repeats (many copies) GAS PF13851.6 KXZ49075.1 - 0.1 11.9 24.7 0.058 12.7 1.5 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CCDC106 PF15794.5 KXZ49075.1 - 0.16 11.6 10.8 2 8.1 0.5 3.4 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 106 Ank_2 PF12796.7 KXZ49076.1 - 2.8e-07 31.0 0.1 0.24 12.0 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49076.1 - 5.2e-07 30.1 0.7 14 6.4 0.9 5.5 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49076.1 - 8e-07 28.9 0.3 19 6.2 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KXZ49076.1 - 0.27 11.6 2.4 2.1 8.8 0.4 3.5 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ49077.1 - 0.00015 22.3 0.3 20 5.9 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49077.1 - 0.00058 20.4 0.0 0.091 13.4 0.0 3.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Defensin_4 PF07936.12 KXZ49077.1 - 0.12 12.2 1.9 6.5 6.7 0.0 3.2 3 0 0 3 3 3 0 Potassium-channel blocking toxin Ank_2 PF12796.7 KXZ49078.1 - 1.2e-07 32.2 0.0 0.4 11.3 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ49078.1 - 1.1e-06 28.5 0.2 39 5.3 0.0 7.3 7 0 0 7 7 7 0 Ankyrin repeat Ank_4 PF13637.6 KXZ49078.1 - 5.7e-06 26.8 2.0 20 5.9 0.1 6.4 4 1 3 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ49078.1 - 0.017 15.5 2.7 2.2 8.7 0.3 4.1 5 1 1 6 6 6 0 Ankyrin repeats (many copies) DUF434 PF04256.12 KXZ49078.1 - 0.047 13.4 0.0 0.17 11.6 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF434) DUF2866 PF11065.8 KXZ49078.1 - 0.66 10.0 2.9 16 5.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2866) Pkinase PF00069.25 KXZ49079.1 - 3.8e-56 190.4 0.0 1.8e-30 106.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49079.1 - 1.5e-25 90.0 0.0 2e-13 50.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KXZ49079.1 - 0.0068 16.4 2.1 0.11 12.3 1.4 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family MORN PF02493.20 KXZ49080.1 - 3.5e-45 149.3 54.8 2.9e-08 33.1 0.1 10.1 10 0 0 10 10 10 9 MORN repeat DUF3135 PF11333.8 KXZ49080.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Ribosomal_L7Ae PF01248.26 KXZ49081.1 - 3.5e-25 87.6 2.8 5.4e-25 87.0 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 KXZ49082.1 - 2.4e-53 181.2 0.0 3.1e-52 177.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49082.1 - 6.3e-24 84.7 0.0 5.9e-11 42.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Peptidase_M11 PF05548.11 KXZ49083.1 - 5.5e-90 301.7 4.0 9.3e-76 255.0 1.4 2.1 1 1 1 2 2 2 2 Gametolysin peptidase M11 TSC22 PF01166.18 KXZ49084.1 - 8.2 6.8 8.0 1.2 9.4 0.2 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family Flavodoxin_1 PF00258.25 KXZ49085.1 - 4.3e-22 78.9 0.4 1.1e-17 64.6 0.0 3.1 3 0 0 3 3 3 2 Flavodoxin Radical_SAM PF04055.21 KXZ49085.1 - 1.8e-06 28.5 0.0 2.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily ANAPC15 PF15243.6 KXZ49085.1 - 0.66 10.4 7.7 1.3 9.4 7.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Ank_2 PF12796.7 KXZ49086.1 - 7.8e-12 45.6 0.1 0.00013 22.5 0.0 3.7 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49086.1 - 2.4e-09 37.5 4.0 0.3 11.7 0.1 6.5 3 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49086.1 - 5e-07 29.5 0.1 9.1 7.2 0.0 7.4 7 1 1 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ49086.1 - 0.00083 19.6 4.5 2.4 8.6 0.0 5.2 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Defensin_4 PF07936.12 KXZ49086.1 - 0.34 10.8 4.3 25 4.8 0.1 4.0 4 0 0 4 4 4 0 Potassium-channel blocking toxin AAA_6 PF12774.7 KXZ49087.1 - 1.3e-157 523.9 0.0 4e-157 522.3 0.0 1.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ49087.1 - 8.7e-111 370.8 0.2 1e-108 364.0 0.2 2.6 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXZ49087.1 - 9.9e-101 336.4 0.0 2e-100 335.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXZ49087.1 - 2e-89 298.5 1.2 2.6e-89 298.1 0.1 1.8 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ49087.1 - 1.4e-62 210.4 0.0 1.9e-49 167.6 0.0 3.8 2 1 1 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 KXZ49087.1 - 6.2e-49 166.9 9.1 6.2e-49 166.9 9.1 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KXZ49087.1 - 2.3e-27 95.6 0.0 9.9e-27 93.6 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ49087.1 - 1.1e-14 54.5 0.0 3.4e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ49087.1 - 1.1e-14 54.6 0.0 0.079 12.9 0.0 7.1 5 2 1 6 6 6 4 AAA domain (dynein-related subfamily) AAA PF00004.29 KXZ49087.1 - 7.8e-05 23.1 0.5 0.23 11.9 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) HOOK PF05622.12 KXZ49087.1 - 0.00086 17.6 5.1 0.0018 16.6 1.1 2.6 2 0 0 2 2 2 1 HOOK protein AAA_18 PF13238.6 KXZ49087.1 - 0.019 15.5 0.0 0.28 11.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXZ49087.1 - 0.037 14.4 7.9 0.47 10.8 0.0 5.7 6 1 0 6 6 5 0 AAA ATPase domain AAA_22 PF13401.6 KXZ49087.1 - 0.13 12.5 0.1 19 5.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain KxDL PF10241.9 KXZ49087.1 - 0.21 11.9 1.7 5.9 7.2 0.4 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein CENP-Q PF13094.6 KXZ49087.1 - 0.21 11.8 3.5 1.1 9.5 3.5 2.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1992 PF09350.10 KXZ49087.1 - 0.78 9.9 2.4 55 4.0 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1992) Taxilin PF09728.9 KXZ49087.1 - 1.1 8.3 7.8 8.4 5.5 3.3 2.8 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Ank_4 PF13637.6 KXZ49088.1 - 3.5e-05 24.3 0.4 1.4 9.5 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49088.1 - 0.00016 22.2 1.1 0.0075 16.8 1.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ49088.1 - 0.0074 16.6 2.1 0.87 10.0 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF4224 PF13986.6 KXZ49088.1 - 0.068 13.1 0.1 3.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4224) Ank_3 PF13606.6 KXZ49088.1 - 0.12 13.0 0.1 17 6.4 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat LCE PF14672.6 KXZ49089.1 - 0.088 13.4 0.3 0.088 13.4 0.3 4.1 5 0 0 5 5 5 0 Late cornified envelope BACK PF07707.15 KXZ49090.1 - 0.00011 22.3 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch His_Phos_1 PF00300.22 KXZ49091.1 - 5e-22 78.6 0.2 7.7e-21 74.7 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AF-4 PF05110.13 KXZ49091.1 - 0.14 10.2 0.3 0.18 9.8 0.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 KXZ49092.1 - 1.6e-28 100.9 1.9 5.7e-19 69.4 0.2 3.0 2 1 1 3 3 3 2 Transcription factor IIA, alpha/beta subunit Kinesin_assoc PF16183.5 KXZ49092.1 - 0.02 15.0 0.1 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Kinesin-associated dCMP_cyt_deam_2 PF08211.12 KXZ49092.1 - 0.026 14.7 4.0 0.057 13.6 4.0 1.6 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region FAM222A PF15258.6 KXZ49092.1 - 0.17 11.0 18.1 0.24 10.5 18.1 1.2 1 0 0 1 1 1 0 Protein family of FAM222A FAM70 PF14967.6 KXZ49092.1 - 2.8 7.3 4.3 3.8 6.9 4.3 1.1 1 0 0 1 1 1 0 FAM70 protein Methyltransf_25 PF13649.6 KXZ49093.1 - 7.6e-25 87.5 0.0 1.6e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ49093.1 - 1.5e-24 86.4 0.0 4.6e-24 84.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ49093.1 - 7.7e-23 81.0 0.0 1.2e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ49093.1 - 8.9e-19 67.9 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ49093.1 - 1.1e-16 61.4 0.0 3.4e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ49093.1 - 1.8e-16 60.2 0.0 3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KXZ49093.1 - 1e-13 51.2 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 KXZ49093.1 - 3.6e-08 32.4 0.0 5.3e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KXZ49093.1 - 3.8e-06 26.5 0.0 0.00017 21.1 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXZ49093.1 - 1.3e-05 24.9 0.0 2.7e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KXZ49093.1 - 0.00014 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KXZ49093.1 - 0.00017 21.4 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KXZ49093.1 - 0.00022 20.9 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.12 KXZ49093.1 - 0.00041 19.9 0.0 0.00062 19.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 KXZ49093.1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 KXZ49093.1 - 0.0013 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KXZ49093.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 KXZ49093.1 - 0.0058 16.0 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KXZ49093.1 - 0.0083 16.3 0.0 0.081 13.0 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KXZ49093.1 - 0.0086 17.1 0.0 0.016 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXZ49093.1 - 0.014 15.3 0.0 0.044 13.6 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase TPMT PF05724.11 KXZ49093.1 - 0.019 14.6 0.0 0.16 11.6 0.0 2.1 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NAS PF03059.16 KXZ49093.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein RrnaAD PF00398.20 KXZ49093.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 KXZ49093.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Shikimate_DH PF01488.20 KXZ49093.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Myb_DNA-bind_6 PF13921.6 KXZ49095.1 - 0.045 14.0 0.7 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pes-10 PF07149.11 KXZ49095.1 - 0.23 10.5 6.8 0.48 9.4 6.8 1.5 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 KXZ49095.1 - 0.85 7.7 9.3 1.8 6.6 9.3 1.5 1 0 0 1 1 1 0 DNA polymerase phi PanZ PF12568.8 KXZ49096.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_1 PF00583.25 KXZ49096.1 - 0.026 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ49096.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KXZ49099.1 - 3.8e-25 88.3 0.0 5.7e-11 42.9 0.0 5.4 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49099.1 - 3.6e-19 68.9 0.9 2.9e-10 40.4 0.0 6.0 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49099.1 - 4.7e-19 66.5 6.2 0.0092 16.4 0.0 8.5 10 1 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 KXZ49099.1 - 3.8e-16 58.9 9.9 0.0049 17.1 0.4 8.2 6 4 4 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49099.1 - 8.2e-15 54.5 4.9 0.44 11.1 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat SnoaL_2 PF12680.7 KXZ49099.1 - 0.15 12.7 0.5 2.3 8.9 0.1 2.6 2 0 0 2 2 2 0 SnoaL-like domain B12-binding_2 PF02607.17 KXZ49099.1 - 5.8 7.4 6.7 1e+02 3.4 0.0 4.2 3 1 0 3 3 3 0 B12 binding domain UvrD_C_2 PF13538.6 KXZ49100.1 - 0.013 15.3 0.5 0.18 11.6 0.0 2.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXZ49100.1 - 0.084 13.2 0.3 3.2 8.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain C2-C2_1 PF11618.8 KXZ49100.1 - 0.12 12.5 2.5 0.25 11.4 2.5 1.5 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 AAA_22 PF13401.6 KXZ49100.1 - 0.16 12.3 0.0 0.82 9.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXZ49100.1 - 8 6.7 21.1 2.1 8.6 1.4 5.4 4 1 0 5 5 5 0 AAA domain DUF1330 PF07045.11 KXZ49102.1 - 0.02 15.2 0.4 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) DHC_N1 PF08385.12 KXZ49103.1 - 3.1e-155 518.0 0.1 3.1e-155 518.0 0.1 4.4 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KXZ49103.1 - 1.3e-146 487.8 0.0 1.3e-144 481.2 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 KXZ49103.1 - 1.4e-108 362.2 0.0 8.2e-108 359.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 KXZ49103.1 - 3.1e-104 349.3 17.0 6.9e-98 328.3 6.4 4.5 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXZ49103.1 - 1.2e-103 346.6 0.0 5.7e-103 344.3 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KXZ49103.1 - 2.9e-88 294.7 5.1 4.1e-87 290.9 1.5 3.3 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ49103.1 - 2.7e-71 238.8 0.0 6.3e-68 227.9 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ49103.1 - 3.2e-54 183.2 0.0 7.8e-54 181.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXZ49103.1 - 7.5e-46 156.7 15.0 7.5e-46 156.7 15.0 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXZ49103.1 - 1e-43 148.2 0.0 1.6e-41 141.1 0.0 3.6 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KXZ49103.1 - 9.6e-30 103.4 0.0 4.5e-11 42.9 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KXZ49103.1 - 2.4e-28 98.8 0.0 7.8e-28 97.1 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ49103.1 - 1.2e-15 57.5 0.7 8.5e-14 51.6 0.0 3.7 3 0 0 3 3 2 1 AAA+ lid domain AAA PF00004.29 KXZ49103.1 - 4.2e-10 40.2 0.8 0.0032 17.9 0.0 4.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ49103.1 - 2.3e-08 34.4 0.2 0.0019 18.5 0.0 4.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXZ49103.1 - 0.0011 19.4 13.5 0.52 10.7 0.1 8.0 7 2 0 7 7 7 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KXZ49103.1 - 0.0015 17.9 0.0 1.3 8.4 0.0 3.0 2 0 0 2 2 2 2 FtsK/SpoIIIE family Sigma54_activat PF00158.26 KXZ49103.1 - 0.0017 18.1 0.0 0.31 10.7 0.0 3.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.6 KXZ49103.1 - 0.0061 16.3 0.1 8.6 6.2 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXZ49103.1 - 0.018 15.6 0.2 25 5.4 0.1 4.2 3 0 0 3 3 3 0 ABC transporter Mg_chelatase PF01078.21 KXZ49103.1 - 0.041 13.3 0.1 12 5.2 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXZ49103.1 - 0.086 13.4 0.1 25 5.4 0.0 3.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXZ49103.1 - 0.095 13.1 0.1 38 4.7 0.0 3.7 4 0 0 4 4 3 0 RNA helicase Arrestin_C PF02752.22 KXZ49105.1 - 1.2e-07 32.2 0.0 4.9e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXZ49105.1 - 1.2e-05 25.4 0.0 3.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KXZ49105.1 - 0.011 14.9 0.8 1.9 7.6 0.1 2.8 2 1 1 3 3 3 0 Rgp1 AAA PF00004.29 KXZ49107.1 - 4.6e-41 140.3 0.0 2.3e-40 138.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ49107.1 - 6e-11 42.0 0.0 1.5e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ49107.1 - 3.9e-05 23.7 0.1 0.00022 21.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXZ49107.1 - 8.6e-05 22.7 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXZ49107.1 - 0.00068 19.9 0.0 0.028 14.7 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.6 KXZ49107.1 - 0.00087 19.5 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ49107.1 - 0.00095 19.6 0.1 0.0077 16.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXZ49107.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KXZ49107.1 - 0.0015 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KXZ49107.1 - 0.0056 16.9 0.0 0.0094 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXZ49107.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXZ49107.1 - 0.0064 17.0 0.0 0.035 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ49107.1 - 0.0087 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KXZ49107.1 - 0.014 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 KXZ49107.1 - 0.018 14.5 0.0 0.052 13.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXZ49107.1 - 0.02 14.8 0.0 0.91 9.4 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXZ49107.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KXZ49107.1 - 0.036 13.8 0.1 0.24 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KXZ49107.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXZ49107.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 KXZ49107.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Histone PF00125.24 KXZ49107.1 - 0.13 12.6 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Zeta_toxin PF06414.12 KXZ49107.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 KXZ49107.1 - 0.18 10.8 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Methyltransf_25 PF13649.6 KXZ49108.1 - 3.8e-18 66.0 0.0 5.9e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ49108.1 - 1.2e-17 64.3 0.0 1.9e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ49108.1 - 1.1e-14 54.3 0.0 2e-13 50.2 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXZ49108.1 - 2.3e-14 53.4 0.0 3.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ49108.1 - 2.1e-10 41.2 0.0 3.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ49108.1 - 3.5e-07 30.2 0.0 5.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 KXZ49108.1 - 0.0019 17.6 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G RrnaAD PF00398.20 KXZ49108.1 - 0.0097 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KXZ49108.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXZ49108.1 - 0.026 13.8 0.0 0.056 12.7 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_9 PF08003.11 KXZ49108.1 - 0.034 13.1 0.0 0.33 9.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) RNase_PH PF01138.21 KXZ49109.1 - 1.9e-21 76.9 0.1 3.6e-21 76.0 0.0 1.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXZ49109.1 - 0.069 13.2 0.0 0.81 9.8 0.0 2.4 2 1 0 2 2 2 0 3' exoribonuclease family, domain 2 Ank_2 PF12796.7 KXZ49110.1 - 1.9e-40 137.3 0.8 6.8e-14 52.2 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49110.1 - 9.2e-29 99.5 4.4 3.6e-08 33.8 0.1 4.9 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49110.1 - 3.5e-25 85.3 0.3 0.00041 20.6 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXZ49110.1 - 1.5e-24 85.3 0.7 0.003 17.9 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXZ49110.1 - 2.2e-24 85.2 1.0 3.6e-06 27.1 0.0 5.2 2 1 4 6 6 6 5 Ankyrin repeats (many copies) LRR_9 PF14580.6 KXZ49111.1 - 6.1e-11 42.1 3.8 4.2e-10 39.4 3.0 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KXZ49111.1 - 2.9e-09 37.0 14.7 0.00061 20.1 6.5 3.3 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ49111.1 - 6.3e-08 32.3 5.7 1.3e-06 28.1 2.1 2.7 2 2 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KXZ49111.1 - 0.068 13.2 3.9 3 8.1 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KXZ49111.1 - 1.3 9.9 9.3 43 5.2 0.5 4.0 4 1 0 4 4 4 0 Leucine Rich Repeat APG6_N PF17675.1 KXZ49112.1 - 0.34 11.5 7.7 2.8 8.5 0.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2894 PF11445.8 KXZ49112.1 - 1.4 9.4 7.4 5 7.6 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) Tic22 PF04278.12 KXZ49113.1 - 5.7e-47 160.2 1.7 3e-42 144.7 0.5 2.1 2 0 0 2 2 2 2 Tic22-like family LppC PF04348.13 KXZ49113.1 - 0.043 12.6 2.2 0.097 11.5 2.2 1.5 2 0 0 2 2 2 0 LppC putative lipoprotein zf-C3HC4_2 PF13923.6 KXZ49114.1 - 3.8e-07 29.9 12.9 6.6e-07 29.1 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ49114.1 - 8.9e-07 28.7 12.3 1.5e-06 27.9 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ49114.1 - 1.1e-05 25.3 14.2 1.8e-05 24.6 14.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ49114.1 - 0.00014 21.6 14.9 0.00025 20.9 14.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ49114.1 - 0.00036 20.8 12.6 0.0006 20.1 12.6 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXZ49114.1 - 0.00048 19.9 10.4 0.00085 19.1 10.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF4201 PF13870.6 KXZ49114.1 - 0.017 14.8 1.3 0.017 14.8 1.3 7.6 5 2 2 7 7 7 0 Domain of unknown function (DUF4201) zf-rbx1 PF12678.7 KXZ49114.1 - 0.056 13.7 7.1 0.12 12.7 7.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain AhpC-TSA PF00578.21 KXZ49114.1 - 0.062 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 AhpC/TSA family zf-RING_UBOX PF13445.6 KXZ49114.1 - 0.35 10.9 10.0 0.65 10.1 10.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KXZ49114.1 - 5.8 6.8 9.7 12 5.7 9.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain F5_F8_type_C PF00754.25 KXZ49117.1 - 6.7e-07 29.5 0.4 1.9e-06 28.0 0.4 1.8 1 0 0 1 1 1 1 F5/8 type C domain EGF_CA PF07645.15 KXZ49117.1 - 0.0038 17.4 1.7 0.0038 17.4 1.7 5.4 6 1 1 7 7 7 1 Calcium-binding EGF domain DUF2173 PF09941.9 KXZ49117.1 - 0.082 13.2 0.4 18 5.7 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2173) PAN_4 PF14295.6 KXZ49117.1 - 0.12 12.3 0.0 0.12 12.3 0.0 5.4 5 0 0 5 5 5 0 PAN domain cEGF PF12662.7 KXZ49117.1 - 0.15 12.0 10.5 2.9 7.9 2.1 3.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like Na_Ca_ex PF01699.24 KXZ49118.1 - 8.2e-30 103.8 24.1 3.6e-17 62.7 10.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein AAA PF00004.29 KXZ49119.1 - 2.6e-40 137.9 0.0 1.4e-39 135.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KXZ49119.1 - 6.1e-35 120.8 0.2 1.1e-34 120.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA_5 PF07728.14 KXZ49119.1 - 4.1e-06 26.8 0.1 1.4e-05 25.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXZ49119.1 - 7.3e-05 22.6 0.0 0.00035 20.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ49119.1 - 7.9e-05 23.1 1.4 0.0057 17.1 0.2 3.0 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 KXZ49119.1 - 0.00081 18.7 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXZ49119.1 - 0.0011 19.2 1.4 0.037 14.3 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KXZ49119.1 - 0.0042 17.4 0.4 0.0096 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXZ49119.1 - 0.0042 16.8 0.2 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 KXZ49119.1 - 0.0048 16.3 0.1 0.36 10.1 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.6 KXZ49119.1 - 0.012 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXZ49119.1 - 0.013 14.9 0.4 0.036 13.4 0.3 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXZ49119.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KXZ49119.1 - 0.017 15.2 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KXZ49119.1 - 0.05 13.1 0.2 0.3 10.6 0.2 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KXZ49119.1 - 0.057 13.4 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXZ49119.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXZ49119.1 - 0.088 13.2 0.2 0.23 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 KXZ49119.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KXZ49119.1 - 0.19 11.7 0.1 1 9.3 0.2 2.0 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 KXZ49119.1 - 0.25 10.8 0.6 0.54 9.7 0.6 1.5 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KXZ49119.1 - 5.2 6.3 5.2 1.3 8.3 0.8 2.2 2 1 0 2 2 2 0 Zeta toxin LRR_6 PF13516.6 KXZ49120.1 - 9.5e-12 44.0 15.6 0.081 13.0 0.0 9.4 12 0 0 12 12 12 4 Leucine Rich repeat Thioredoxin PF00085.20 KXZ49120.1 - 1.1e-10 41.4 0.0 0.00055 19.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin LRR_4 PF12799.7 KXZ49120.1 - 1e-08 35.3 2.5 0.91 10.0 0.2 6.8 6 2 1 7 7 7 2 Leucine Rich repeats (2 copies) HyaE PF07449.11 KXZ49120.1 - 0.0012 18.8 0.0 0.89 9.5 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KXZ49120.1 - 0.0018 18.7 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Glyco_hydro_9 PF00759.19 KXZ49121.1 - 1.9e-42 146.2 1.3 3e-42 145.5 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CelD_N PF02927.14 KXZ49121.1 - 4.8e-13 49.8 0.0 1.4e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 Cellulase N-terminal ig-like domain Laminin_G_3 PF13385.6 KXZ49121.1 - 1.9e-10 41.1 7.5 0.016 15.4 0.1 5.4 5 0 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily Mito_carr PF00153.27 KXZ49123.1 - 8.5e-68 224.4 3.0 3e-21 75.1 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein VPS13 PF16908.5 KXZ49125.1 - 5.7e-46 157.2 0.0 8.2e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KXZ49125.1 - 7.3e-28 97.0 0.0 1.3e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Vps62 PF06101.11 KXZ49125.1 - 8.5e-21 73.9 0.1 0.0001 20.8 0.0 6.0 5 1 1 6 6 6 5 Vacuolar protein sorting-associated protein 62 VPS13_mid_rpt PF16910.5 KXZ49125.1 - 9.8e-09 35.0 0.0 2e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Repeating coiled region of VPS13 ADP_ribosyl_GH PF03747.14 KXZ49126.1 - 1.8e-50 172.3 0.7 3e-50 171.6 0.7 1.4 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase Gly-zipper_OmpA PF13436.6 KXZ49126.1 - 0.053 13.3 0.9 0.053 13.3 0.9 2.0 2 0 0 2 2 2 0 Glycine-zipper domain Pea-VEAacid PF08111.11 KXZ49126.1 - 0.064 13.6 1.0 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Pea-VEAacid family Gly-zipper_YMGG PF13441.6 KXZ49126.1 - 0.23 11.2 9.8 0.16 11.7 1.5 2.9 3 0 0 3 3 3 0 YMGG-like Gly-zipper Pkinase PF00069.25 KXZ49127.1 - 5.7e-32 111.1 0.0 3.8e-21 75.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49127.1 - 1.9e-11 43.7 0.0 5e-06 26.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ49127.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.32 KXZ49128.1 - 3e-06 27.9 8.1 0.034 15.0 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat 2OG-FeII_Oxy_3 PF13640.6 KXZ49129.1 - 2.9e-18 66.5 0.0 5.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ49129.1 - 3.4e-10 40.3 0.0 4.8e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily X PF00739.19 KXZ49130.1 - 2.1 8.5 5.7 22 5.2 0.0 2.6 2 1 0 2 2 2 0 Trans-activation protein X Pkinase_Tyr PF07714.17 KXZ49131.1 - 6.3e-45 153.5 0.0 3.9e-25 88.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49131.1 - 2.9e-39 135.0 0.0 7.8e-25 87.7 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ49131.1 - 0.00075 19.5 3.0 0.027 14.4 0.1 3.0 1 1 2 3 3 3 2 Phosphotransferase enzyme family p450 PF00067.22 KXZ49132.1 - 7.3e-73 245.9 0.0 3.9e-58 197.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 PolyA_pol PF01743.20 KXZ49133.1 - 5.2e-09 36.6 0.7 4.4e-06 27.1 0.0 3.2 3 0 0 3 3 3 2 Poly A polymerase head domain Pkinase PF00069.25 KXZ49134.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain NUDIX PF00293.28 KXZ49135.1 - 0.1 12.6 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 NUDIX domain DUF615 PF04751.14 KXZ49136.1 - 1.8e-17 63.8 0.4 3.9e-17 62.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF615) FAST_1 PF06743.15 KXZ49137.1 - 0.0012 18.7 0.0 0.17 11.8 0.0 2.8 2 0 0 2 2 2 2 FAST kinase-like protein, subdomain 1 Rnk_N PF14760.6 KXZ49137.1 - 3.4 8.2 7.8 0.92 10.0 0.6 3.4 2 0 0 2 2 2 0 Rnk N-terminus Chloroa_b-bind PF00504.21 KXZ49138.1 - 2.4e-11 44.4 4.3 4.1e-06 27.4 0.1 2.2 1 1 1 2 2 2 2 Chlorophyll A-B binding protein Ank_2 PF12796.7 KXZ49139.1 - 0.0011 19.6 0.0 0.0019 18.7 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49139.1 - 0.0072 16.9 0.1 0.037 14.6 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49139.1 - 0.032 14.8 0.2 0.37 11.5 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeat SelB-wing_1 PF09105.10 KXZ49139.1 - 0.22 11.5 3.4 4.2 7.4 0.6 2.5 1 1 1 2 2 2 0 Elongation factor SelB, winged helix Fer2 PF00111.27 KXZ49140.1 - 1.1e-18 66.9 0.2 1.7e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 KXZ49140.1 - 0.0058 16.6 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zn_Tnp_IS91 PF14319.6 KXZ49140.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Acetyltransf_1 PF00583.25 KXZ49141.1 - 5.2e-16 58.9 0.0 9.2e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ49141.1 - 1.5e-10 41.3 0.0 2.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ49141.1 - 1.7e-09 37.7 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXZ49141.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ49141.1 - 0.00014 21.7 0.1 0.00022 21.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXZ49141.1 - 0.015 16.0 0.0 0.019 15.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ49141.1 - 0.028 14.5 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TYW3 PF02676.14 KXZ49142.1 - 2.1e-28 99.2 0.0 3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 KGG PF10685.9 KXZ49142.1 - 2.1 8.8 5.4 2.8 8.3 1.0 2.5 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif Cupin_8 PF13621.6 KXZ49143.1 - 1.9e-29 103.1 0.0 2.2e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXZ49143.1 - 8e-08 32.1 0.1 1.2e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Cupin superfamily protein malic PF00390.19 KXZ49144.1 - 3.4e-08 33.5 0.0 3.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SKG6 PF08693.10 KXZ49145.1 - 0.34 10.4 0.1 0.34 10.4 0.1 2.6 3 0 0 3 3 3 0 Transmembrane alpha-helix domain CAP PF00188.26 KXZ49147.1 - 6.3e-21 75.5 1.1 1.3e-20 74.5 1.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GCK PF07802.11 KXZ49148.1 - 5.7e-05 23.5 2.4 6.6e-05 23.3 2.4 1.1 1 0 0 1 1 1 1 GCK domain CX9C PF16860.5 KXZ49148.1 - 0.00016 21.6 1.3 0.0002 21.3 1.3 1.1 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 KXZ49148.1 - 0.00066 20.0 3.8 0.001 19.4 3.8 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 KXZ49148.1 - 0.0033 17.6 0.8 0.0038 17.4 0.8 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 KXZ49148.1 - 0.007 16.5 6.5 0.03 14.5 6.3 1.8 1 1 1 2 2 2 2 CHCH domain Cmc1 PF08583.10 KXZ49148.1 - 0.0093 16.0 1.8 0.013 15.6 1.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KXZ49148.1 - 0.027 14.7 0.9 0.036 14.3 0.9 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 KXZ49148.1 - 0.048 13.9 1.6 0.68 10.2 1.6 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) PAP2 PF01569.21 KXZ49149.1 - 6.4e-14 51.9 1.9 6.4e-14 51.9 1.9 2.0 1 1 1 2 2 2 1 PAP2 superfamily CD225 PF04505.12 KXZ49149.1 - 0.095 12.8 0.5 0.51 10.5 0.0 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein DUF2722 PF10846.8 KXZ49149.1 - 0.74 8.7 10.5 0.11 11.4 6.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RAM PF15320.6 KXZ49149.1 - 1.8 9.2 10.6 2.1 9.0 3.0 2.7 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Spt20 PF12090.8 KXZ49149.1 - 2.2 7.9 18.5 0.77 9.3 12.8 2.0 2 0 0 2 2 2 0 Spt20 family Peptidase_S8 PF00082.22 KXZ49150.1 - 1e-29 103.8 0.4 3.1e-21 75.9 0.0 2.6 1 1 1 2 2 2 2 Subtilase family FH2 PF02181.23 KXZ49152.1 - 0.048 12.8 4.9 0.06 12.5 1.0 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain Seryl_tRNA_N PF02403.22 KXZ49152.1 - 0.42 10.9 16.4 0.29 11.4 3.9 3.4 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF5339 PF17274.2 KXZ49152.1 - 1.1 10.2 3.2 5.1 8.0 0.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5339) LUC7 PF03194.15 KXZ49152.1 - 1.2 8.8 9.1 3.4 7.3 9.1 1.7 1 1 0 1 1 1 0 LUC7 N_terminus FAM184 PF15665.5 KXZ49152.1 - 2.4 7.9 16.6 5.7 6.7 16.6 1.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF4618 PF15397.6 KXZ49152.1 - 3.6 6.9 6.6 1.3 8.4 0.4 2.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) DnaJ_CXXCXGXG PF00684.19 KXZ49153.1 - 0.013 15.8 18.4 0.59 10.5 5.0 3.2 2 2 0 2 2 2 0 DnaJ central domain DUF1356 PF07092.12 KXZ49153.1 - 0.095 12.0 4.4 1.4 8.2 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1356) VWA_N2 PF16164.5 KXZ49153.1 - 0.65 10.2 5.6 11 6.2 0.9 2.3 2 0 0 2 2 2 0 VWA N-terminal Anti-TRAP PF15777.5 KXZ49153.1 - 0.68 9.9 16.6 0.99 9.4 5.5 3.4 2 2 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein PMM PF03332.13 KXZ49155.1 - 1.1e-108 362.1 0.9 1.3e-108 361.9 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KXZ49155.1 - 1.4e-08 34.8 0.0 5.5e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXZ49155.1 - 5.5e-05 22.8 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KXZ49155.1 - 0.29 11.4 1.1 1.9 8.7 1.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CTP_transf_like PF01467.26 KXZ49156.1 - 5.4e-17 62.3 0.0 1.4e-11 44.8 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like Ank_5 PF13857.6 KXZ49157.1 - 1.6e-08 34.7 0.1 0.00015 22.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49157.1 - 7.4e-08 32.1 0.1 0.0014 19.0 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KXZ49157.1 - 1.9e-07 31.2 0.2 0.00039 20.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXZ49157.1 - 2e-07 31.5 0.1 0.0002 21.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49157.1 - 4.4e-07 30.3 0.5 0.0099 16.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) FbpA PF05833.11 KXZ49158.1 - 9.6e-20 70.8 0.0 1.1e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) FbpA PF05833.11 KXZ49159.1 - 9.4e-17 60.9 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) GP38 PF05268.11 KXZ49159.1 - 5.5 6.6 21.5 9.4 5.8 21.5 1.3 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Cys_rich_FGFR PF00839.17 KXZ49160.1 - 5.5e-100 327.5 85.8 1.4e-13 50.7 0.3 12.2 11 1 1 12 12 12 12 Cysteine rich repeat CCM2_C PF16545.5 KXZ49160.1 - 0.33 11.5 1.7 32 5.1 0.0 3.5 4 0 0 4 4 4 0 Cerebral cavernous malformation protein, harmonin-homology TauE PF01925.19 KXZ49161.1 - 1.4e-12 47.8 55.5 1.1e-09 38.3 18.7 4.9 4 1 1 5 5 5 2 Sulfite exporter TauE/SafE DUF4381 PF14316.6 KXZ49161.1 - 0.029 14.6 9.8 0.92 9.7 2.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Csm1_N PF18504.1 KXZ49162.1 - 0.079 13.3 0.2 0.21 12.0 0.1 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF16 PF01519.16 KXZ49162.1 - 0.19 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 malic PF00390.19 KXZ49163.1 - 4.5e-68 228.6 0.0 6.2e-68 228.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 KXZ49163.1 - 1e-61 208.5 0.0 1.3e-31 109.8 0.0 2.1 1 1 1 2 2 2 2 Malic enzyme, NAD binding domain FAST_1 PF06743.15 KXZ49165.1 - 1.3e-05 25.1 1.5 0.017 15.1 0.0 4.0 4 1 1 5 5 5 2 FAST kinase-like protein, subdomain 1 PMD PF10536.9 KXZ49165.1 - 0.016 14.3 0.5 0.024 13.8 0.5 1.1 1 0 0 1 1 1 0 Plant mobile domain Spc7 PF08317.11 KXZ49166.1 - 0.00081 18.4 16.6 0.00081 18.4 16.6 19.5 3 2 17 21 21 21 11 Spc7 kinetochore protein Thioesterase PF00975.20 KXZ49167.1 - 2.4e-18 67.1 0.3 2e-14 54.3 0.2 2.1 1 1 1 2 2 2 2 Thioesterase domain Hydrolase_4 PF12146.8 KXZ49167.1 - 3.3e-09 36.4 0.1 3.7e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ49167.1 - 3.9e-09 37.4 11.0 2.5e-08 34.8 2.2 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ49167.1 - 0.00056 19.6 0.0 0.013 15.2 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KXZ49167.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KXZ49167.1 - 0.031 14.0 0.0 0.19 11.5 0.0 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXZ49167.1 - 0.052 13.0 0.3 0.17 11.3 0.3 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KXZ49167.1 - 0.054 13.0 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 KXZ49167.1 - 0.06 12.8 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KXZ49167.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein SF3b10 PF07189.11 KXZ49168.1 - 3.8e-36 123.0 0.0 4.4e-36 122.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DapB_C PF05173.14 KXZ49169.1 - 7.2e-21 74.5 0.2 1e-20 74.0 0.2 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 KXZ49169.1 - 5.6e-11 42.6 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GP44 PF17510.2 KXZ49169.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Gene product 44 Thioredoxin_3 PF13192.6 KXZ49169.1 - 0.026 14.6 0.2 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin domain Ank_5 PF13857.6 KXZ49170.1 - 2.4e-17 62.8 0.5 1.8e-11 44.1 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49170.1 - 5.4e-15 55.7 0.0 8.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49170.1 - 2.7e-14 53.3 0.0 3.1e-06 27.6 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49170.1 - 7.7e-14 51.4 0.7 6.4e-06 26.4 0.4 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXZ49170.1 - 1.9e-10 40.1 0.0 0.0016 18.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Steroid_dh PF02544.16 KXZ49171.1 - 1.6e-35 122.3 0.2 1.5e-30 106.2 0.1 2.2 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXZ49171.1 - 4.9e-05 23.0 1.0 0.0002 21.0 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KXZ49171.1 - 0.001 19.5 0.3 0.0068 16.8 0.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase Rad51 PF08423.11 KXZ49172.1 - 1.2e-47 162.4 0.3 1.8e-46 158.5 0.3 2.0 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KXZ49172.1 - 1.3e-10 41.2 0.9 4.2e-10 39.5 0.9 1.7 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KXZ49172.1 - 8.6e-07 28.5 0.2 4e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 KXZ49172.1 - 0.00022 20.7 0.2 0.0017 17.7 0.2 2.0 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 KXZ49172.1 - 0.0077 15.7 1.4 0.097 12.1 0.2 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_33 PF13671.6 KXZ49172.1 - 0.0089 16.2 0.4 0.023 14.9 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXZ49172.1 - 0.063 13.0 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain E2F_TDP PF02319.20 KXZ49173.1 - 7.2e-16 58.0 0.1 1.2e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain WHAMM-JMY_N PF15920.5 KXZ49173.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated FAST_1 PF06743.15 KXZ49175.1 - 2.6e-08 33.7 0.0 1.4 8.9 0.0 5.5 4 1 2 6 6 6 5 FAST kinase-like protein, subdomain 1 Acid_PPase PF12689.7 KXZ49176.1 - 6.9e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 KXZ49176.1 - 0.0025 18.1 0.0 0.011 16.0 0.0 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXZ49176.1 - 0.026 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase AIM3 PF17096.5 KXZ49176.1 - 0.17 12.9 0.3 0.38 11.7 0.3 1.6 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Acid_PPase PF12689.7 KXZ49177.1 - 0.0014 18.5 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase LAP1C PF05609.12 KXZ49178.1 - 0.26 10.3 17.9 0.33 10.0 17.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TTL PF03133.15 KXZ49179.1 - 2.2e-73 246.9 0.0 4.3e-73 246.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ49179.1 - 6e-08 32.2 0.0 2.4e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ49179.1 - 0.0047 16.2 0.0 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Pox_Ag35 PF03286.14 KXZ49179.1 - 4.1 7.1 5.9 9.2 6.0 5.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tubulin PF00091.25 KXZ49180.1 - 4.6e-54 183.6 0.0 1.1e-53 182.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXZ49180.1 - 8.8e-31 106.7 0.6 6.4e-20 71.6 0.1 2.4 1 1 1 2 2 2 2 Tubulin C-terminal domain Tubulin_2 PF13809.6 KXZ49180.1 - 0.068 12.3 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin like DUF716 PF04819.12 KXZ49181.1 - 3.2e-19 68.9 8.0 7.7e-19 67.7 8.0 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF716) Fe-S_biosyn PF01521.20 KXZ49181.1 - 1.4e-12 47.8 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Guanylate_cyc PF00211.20 KXZ49182.1 - 1.5e-07 31.2 0.0 4e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 KXZ49182.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MORN PF02493.20 KXZ49183.1 - 1.6e-08 33.9 8.3 0.022 14.6 0.3 3.7 3 0 0 3 3 3 3 MORN repeat RAP PF08373.10 KXZ49184.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.8 1 1 0 1 1 1 1 RAP domain AHH PF14412.6 KXZ49184.1 - 0.12 12.4 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH NAD_binding_10 PF13460.6 KXZ49185.1 - 7.4e-32 110.7 0.6 1e-31 110.3 0.6 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXZ49185.1 - 2.5e-07 30.4 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXZ49185.1 - 8.6e-06 26.0 0.4 2.1e-05 24.7 0.2 1.8 2 0 0 2 2 2 1 TrkA-N domain NmrA PF05368.13 KXZ49185.1 - 0.00014 21.5 0.1 0.0004 20.0 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KXZ49185.1 - 0.00042 19.4 0.2 0.00055 19.0 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 KXZ49185.1 - 0.0047 17.3 0.2 0.011 16.2 0.2 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding HIM1 PF08732.10 KXZ49185.1 - 0.007 15.9 0.0 0.017 14.6 0.0 1.7 1 1 0 1 1 1 1 HIM1 AlaDh_PNT_C PF01262.21 KXZ49185.1 - 0.0089 15.3 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.19 KXZ49185.1 - 0.03 13.1 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_4 PF07993.12 KXZ49185.1 - 0.035 13.3 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Peripla_BP_4 PF13407.6 KXZ49185.1 - 0.089 12.3 0.4 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Periplasmic binding protein domain Aquarius_N PF16399.5 KXZ49186.1 - 1.7e-267 889.7 0.0 6.3e-165 550.4 0.0 3.6 3 1 0 3 3 3 3 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 KXZ49186.1 - 1e-23 84.4 0.0 4.4e-23 82.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KXZ49186.1 - 2e-23 83.1 0.0 3.3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ49186.1 - 6.5e-07 29.8 0.3 7e-05 23.2 0.0 2.8 2 1 0 3 3 3 1 AAA domain ResIII PF04851.15 KXZ49186.1 - 0.037 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 KXZ49186.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NAPRTase_N PF17767.1 KXZ49186.1 - 0.071 13.5 1.2 0.13 12.6 0.2 2.0 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain AAA_22 PF13401.6 KXZ49186.1 - 0.083 13.2 0.0 1.5 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXZ49186.1 - 1.1 9.6 0.0 1.1 9.6 0.0 4.2 5 1 1 6 6 6 0 AAA ATPase domain Ribosomal_L27 PF01016.19 KXZ49187.1 - 4.7e-33 113.0 1.1 7.1e-33 112.5 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein FYRN PF05964.14 KXZ49188.1 - 6.1e-13 48.4 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KXZ49188.1 - 1.6e-11 44.2 0.0 8e-11 41.9 0.0 2.3 1 0 0 1 1 1 1 F/Y rich C-terminus GLE1 PF07817.13 KXZ49189.1 - 9.3e-41 139.7 0.0 1.8e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein DUF5427 PF10310.9 KXZ49189.1 - 0.088 11.8 18.7 0.11 11.4 18.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 KXZ49189.1 - 1.2 7.9 20.0 1.7 7.4 20.0 1.2 1 0 0 1 1 1 0 Presenilin Asp-B-Hydro_N PF05279.11 KXZ49189.1 - 1.4 8.9 27.6 2 8.4 27.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NPAT_C PF15712.5 KXZ49189.1 - 7.2 5.1 18.3 9.8 4.7 18.3 1.1 1 0 0 1 1 1 0 NPAT C terminus Pkinase_Tyr PF07714.17 KXZ49190.1 - 4.1e-52 177.0 0.0 5.1e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49190.1 - 2.1e-43 148.6 0.0 1e-30 107.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ49190.1 - 3.1e-05 24.0 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ49190.1 - 0.041 12.8 0.0 0.089 11.7 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain ABC1 PF03109.16 KXZ49190.1 - 0.048 13.8 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 KXZ49190.1 - 0.049 12.4 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KXZ49190.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 EF-hand_1 PF00036.32 KXZ49193.1 - 9.4e-13 46.7 0.0 0.00092 18.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KXZ49193.1 - 1e-11 43.8 0.1 0.0025 17.6 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain DUF4347 PF14252.6 KXZ49193.1 - 6.6e-10 39.1 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) EF-hand_7 PF13499.6 KXZ49193.1 - 1.5e-09 38.2 0.9 0.0023 18.3 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ49193.1 - 3.1e-08 32.7 0.0 0.0013 18.1 0.1 2.8 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KXZ49193.1 - 0.022 15.1 0.2 0.76 10.1 0.1 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SAP18 PF06487.12 KXZ49193.1 - 0.03 14.5 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) REF PF05755.12 KXZ49193.1 - 0.072 12.9 0.8 0.13 12.1 0.8 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF883 PF05957.13 KXZ49193.1 - 0.43 11.2 11.2 1.2 9.8 11.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Gly-zipper_Omp PF13488.6 KXZ49195.1 - 1.2 9.2 65.8 1.9 8.6 13.6 5.1 1 1 4 5 5 5 0 Glycine zipper KRTAP PF11759.8 KXZ49195.1 - 7 7.3 62.4 0.42 11.2 13.3 4.0 2 1 2 4 4 4 0 Keratin-associated matrix SAND PF01342.21 KXZ49196.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 SAND domain MT-A70 PF05063.14 KXZ49197.1 - 4.1e-57 192.8 0.0 7.8e-57 191.9 0.0 1.5 1 0 0 1 1 1 1 MT-A70 TFIIA PF03153.13 KXZ49197.1 - 0.00034 20.7 11.1 0.00034 20.7 11.1 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 KXZ49197.1 - 0.0061 15.6 10.0 0.0061 15.6 10.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Presenilin PF01080.17 KXZ49197.1 - 0.037 12.8 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Presenilin TT_ORF2 PF02957.15 KXZ49197.1 - 0.64 10.9 5.2 2.1 9.2 5.2 1.9 1 0 0 1 1 1 0 TT viral ORF2 AXIN1_TNKS_BD PF16646.5 KXZ49197.1 - 6.5 7.8 8.1 1.9 9.5 4.2 2.1 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain Cupin_2 PF07883.11 KXZ49198.1 - 3.1e-22 78.1 1.7 1.4e-15 56.7 0.7 2.9 3 0 0 3 3 3 2 Cupin domain AraC_binding PF02311.19 KXZ49198.1 - 1.7e-12 47.4 0.1 9.2e-09 35.3 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KXZ49198.1 - 3.6e-10 39.4 0.1 1.6e-05 24.5 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KXZ49198.1 - 7.5e-08 32.1 1.3 2.7e-07 30.3 0.1 2.2 2 1 1 3 3 3 1 Cupin AraC_binding_2 PF14525.6 KXZ49198.1 - 0.0032 17.2 0.0 0.0032 17.2 0.0 3.2 2 1 0 2 2 2 1 AraC-binding-like domain Auxin_BP PF02041.16 KXZ49198.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein MannoseP_isomer PF01050.18 KXZ49198.1 - 0.25 11.2 0.0 0.43 10.5 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase KTI12 PF08433.10 KXZ49199.1 - 0.0014 18.2 0.0 0.0034 16.9 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Tom5 PF10642.9 KXZ49199.1 - 0.038 14.0 1.8 0.11 12.5 1.8 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase AAA_33 PF13671.6 KXZ49199.1 - 0.048 13.8 0.0 0.048 13.8 0.0 2.7 3 1 0 3 3 3 0 AAA domain PIF1 PF05970.14 KXZ49200.1 - 1.6e-29 103.2 0.1 6.8e-21 74.8 0.1 4.0 3 1 0 3 3 3 3 PIF1-like helicase UvrD_C_2 PF13538.6 KXZ49200.1 - 9.6e-20 70.2 0.3 1.4e-06 28.0 0.0 3.8 3 0 0 3 3 3 3 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXZ49200.1 - 1.3e-15 57.6 7.9 4.9e-13 49.2 1.2 4.3 4 1 1 5 5 5 2 AAA domain Herpes_Helicase PF02689.14 KXZ49200.1 - 1.6e-08 33.0 0.5 0.016 13.2 0.0 4.2 4 1 1 5 5 5 2 Helicase AAA_19 PF13245.6 KXZ49200.1 - 7.2e-08 32.9 0.5 2.2e-07 31.3 0.5 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ49200.1 - 9.9e-05 22.6 0.1 0.00023 21.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ49200.1 - 0.0021 17.8 0.2 11 5.7 0.0 3.9 3 2 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KXZ49200.1 - 0.0043 17.5 0.2 0.0043 17.5 0.2 2.4 3 0 0 3 3 3 1 AAA ATPase domain DEAD PF00270.29 KXZ49200.1 - 0.011 15.6 0.6 1.7 8.4 0.1 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.6 KXZ49200.1 - 0.054 13.3 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KXZ49200.1 - 0.087 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KXZ49201.1 - 2.9e-27 95.8 0.4 1.5e-16 60.6 0.1 4.1 3 2 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 KXZ49201.1 - 1.8e-08 34.3 0.2 0.0041 16.9 0.2 4.0 4 0 0 4 4 4 3 AAA domain PAS_4 PF08448.10 KXZ49202.1 - 0.0067 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXZ49202.1 - 0.01 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 KXZ49202.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 KXZ49202.1 - 0.024 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold DUF5466 PF17554.2 KXZ49202.1 - 0.81 9.9 2.8 0.91 9.8 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5466) Aldo_ket_red PF00248.21 KXZ49204.1 - 6.8e-38 130.5 0.0 1.2e-24 87.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Ribosomal_S5 PF00333.20 KXZ49204.1 - 0.052 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Lentiviral_Tat PF02998.14 KXZ49205.1 - 0.08 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Lentiviral Tat protein zf-C3HC4_2 PF13923.6 KXZ49206.1 - 1.1e-08 34.8 5.1 1.1e-08 34.8 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ49206.1 - 3.1e-08 33.4 7.2 5.5e-08 32.5 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ49206.1 - 3.3e-08 33.4 5.9 3.3e-08 33.4 5.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXZ49206.1 - 3.6e-08 33.4 5.2 8.9e-08 32.2 5.2 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KXZ49206.1 - 3.8e-07 29.9 5.7 8.6e-07 28.7 5.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ49206.1 - 2.1e-06 28.0 10.1 3.9e-06 27.1 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXZ49206.1 - 6.8e-05 22.7 7.3 0.00013 21.9 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXZ49206.1 - 0.0002 21.1 11.2 0.00057 19.7 10.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KXZ49206.1 - 0.01 16.0 4.6 0.02 15.0 4.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KXZ49206.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.6 KXZ49206.1 - 0.29 11.0 6.2 1.1 9.1 6.2 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KXZ49206.1 - 1.8 8.9 10.6 5.2 7.4 10.6 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C6H2 PF15801.5 KXZ49206.1 - 5.3 7.4 8.2 30 5.0 4.7 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Aminotran_5 PF00266.19 KXZ49207.1 - 1.2e-42 146.3 0.0 1.4e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXZ49207.1 - 0.0026 17.0 0.0 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXZ49207.1 - 0.0039 15.8 0.0 0.0056 15.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXZ49208.1 - 2.1e-42 145.4 0.0 2.5e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXZ49208.1 - 0.0018 17.5 0.0 0.005 16.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXZ49208.1 - 0.019 13.5 0.0 0.029 12.9 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1664 PF07889.12 KXZ49209.1 - 0.036 14.1 0.3 0.036 14.1 0.3 7.4 7 2 0 7 7 7 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KXZ49209.1 - 0.15 12.5 38.9 1.8 9.1 0.3 11.2 9 4 5 14 14 14 0 Nucleopolyhedrovirus P10 protein TRPM_tetra PF16519.5 KXZ49209.1 - 0.42 10.7 24.9 3 8.0 0.7 9.1 6 2 3 10 10 10 0 Tetramerisation domain of TRPM PKcGMP_CC PF16808.5 KXZ49209.1 - 1.9 8.4 9.3 20 5.1 0.2 5.9 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF948 PF06103.11 KXZ49209.1 - 2.1 8.7 20.4 30 4.9 0.1 8.3 7 2 1 8 8 8 0 Bacterial protein of unknown function (DUF948) FAM104 PF15434.6 KXZ49209.1 - 3.9 8.1 9.0 20 5.8 9.0 2.3 1 0 0 1 1 1 0 Family 104 Spc29 PF17082.5 KXZ49209.1 - 8.1 6.2 15.4 2 8.2 0.0 4.6 4 1 1 5 5 5 0 Spindle Pole Component 29 PLAT PF01477.23 KXZ49210.1 - 3.4e-21 76.0 0.0 4.1e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 PLAT/LH2 domain UbiA PF01040.18 KXZ49211.1 - 5.1e-38 130.8 12.8 5.1e-38 130.8 12.8 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family ATPase_gene1 PF09527.10 KXZ49211.1 - 0.0089 16.2 1.0 0.0089 16.2 1.0 3.5 4 0 0 4 4 4 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF4079 PF13301.6 KXZ49212.1 - 2.7e-27 95.7 5.8 4.1e-27 95.1 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 KXZ49212.1 - 0.0026 17.9 3.2 0.021 14.9 3.0 2.3 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4405 PF14358.6 KXZ49212.1 - 0.9 10.1 6.5 29 5.3 6.5 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 KXZ49212.1 - 2 8.0 11.2 9.6 5.8 11.0 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 CUE PF02845.16 KXZ49213.1 - 9.2e-08 31.7 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain ETC_C1_NDUFA5 PF04716.14 KXZ49214.1 - 6.8e-16 57.8 0.2 9.5e-16 57.4 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region PI_PP_C PF18365.1 KXZ49214.1 - 0.046 13.7 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain NifU_N PF01592.16 KXZ49215.1 - 4.8e-54 181.9 0.1 5.9e-54 181.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_L22 PF00237.19 KXZ49216.1 - 7.6e-41 138.5 0.2 9.9e-41 138.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IF3_C PF00707.22 KXZ49217.1 - 4.3e-12 45.8 0.0 5.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain SRP54 PF00448.22 KXZ49218.1 - 3.9e-76 255.1 1.1 7.2e-76 254.2 1.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KXZ49218.1 - 7.9e-22 77.7 1.2 7.9e-22 77.7 1.2 2.8 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 KXZ49218.1 - 6.3e-18 64.8 3.7 7.8e-18 64.5 2.0 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 KXZ49218.1 - 2.7e-05 24.4 0.1 7.9e-05 22.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain cobW PF02492.19 KXZ49218.1 - 7.3e-05 22.4 0.1 0.0006 19.4 0.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 KXZ49218.1 - 0.00044 19.7 0.2 1.1 8.7 0.0 3.0 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 KXZ49218.1 - 0.0018 18.7 0.2 0.007 16.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ49218.1 - 0.0061 16.3 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXZ49218.1 - 0.008 16.3 0.2 0.075 13.1 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXZ49218.1 - 0.0081 16.4 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXZ49218.1 - 0.011 15.8 0.7 0.032 14.2 0.7 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KXZ49218.1 - 0.031 14.6 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 KXZ49218.1 - 0.034 13.1 0.0 0.12 11.3 0.0 1.9 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KXZ49218.1 - 0.06 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KXZ49218.1 - 0.086 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KXZ49218.1 - 0.087 12.6 0.3 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KXZ49218.1 - 0.095 11.8 0.1 0.28 10.3 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 KXZ49218.1 - 0.1 13.0 0.4 1.9 8.9 0.4 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KXZ49218.1 - 0.13 11.6 0.6 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 KaiC DUF2209 PF09974.9 KXZ49218.1 - 0.14 12.5 0.2 0.34 11.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) PduV-EutP PF10662.9 KXZ49218.1 - 0.19 11.5 2.5 3.7 7.3 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF3054 PF11255.8 KXZ49219.1 - 1.8e-24 86.4 3.4 2.4e-24 86.0 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) CAP59_mtransfer PF11735.8 KXZ49220.1 - 1.1e-56 192.2 0.0 1.4e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FAM199X PF15814.5 KXZ49220.1 - 0.18 10.8 3.2 0.29 10.2 3.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X Med3 PF11593.8 KXZ49220.1 - 0.26 10.5 0.5 0.36 10.0 0.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TIG PF01833.24 KXZ49222.1 - 1.3e-37 127.8 46.6 6.4e-09 35.8 1.4 9.1 8 1 1 9 9 9 6 IPT/TIG domain PA14 PF07691.12 KXZ49222.1 - 0.028 14.2 0.3 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 PA14 domain GLEYA PF10528.9 KXZ49222.1 - 0.03 14.7 0.1 0.15 12.5 0.1 2.2 1 0 0 1 1 1 0 GLEYA domain G8 PF10162.9 KXZ49223.1 - 6e-59 197.5 0.0 1.4e-29 102.6 0.0 3.0 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 KXZ49223.1 - 3.3e-27 94.4 30.9 7.1e-14 51.7 0.6 5.5 4 0 0 4 4 4 3 IPT/TIG domain Beta_helix PF13229.6 KXZ49223.1 - 3.2e-07 30.3 12.7 0.00067 19.5 0.7 4.0 3 2 0 3 3 3 2 Right handed beta helix region ABM PF03992.16 KXZ49224.1 - 3.2e-06 27.2 0.2 3.2e-06 27.2 0.2 2.8 2 0 0 2 2 1 1 Antibiotic biosynthesis monooxygenase KASH_CCD PF14662.6 KXZ49224.1 - 0.00012 22.0 44.4 0.0084 16.0 24.3 4.2 3 2 1 4 4 4 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KXZ49224.1 - 0.0047 17.0 53.0 0.65 10.0 9.9 5.8 2 2 3 5 5 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KXZ49224.1 - 0.0056 15.6 52.5 0.017 14.1 20.4 3.2 2 1 1 3 3 3 2 Spc7 kinetochore protein APG6_N PF17675.1 KXZ49224.1 - 0.0075 16.8 17.0 0.0075 16.8 17.0 5.3 2 2 2 5 5 5 1 Apg6 coiled-coil region Phage_GP20 PF06810.11 KXZ49224.1 - 0.046 13.5 23.0 0.19 11.5 2.3 3.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 Golgin_A5 PF09787.9 KXZ49224.1 - 0.046 13.2 47.7 0.015 14.8 9.1 3.7 2 2 0 3 3 3 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KXZ49224.1 - 0.073 13.1 23.7 1.2 9.1 0.3 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KXZ49224.1 - 0.084 12.0 39.4 0.026 13.6 12.6 3.0 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Goodbye PF17109.5 KXZ49224.1 - 0.11 12.9 0.2 0.11 12.9 0.2 3.6 3 1 1 4 4 4 0 fungal STAND N-terminal Goodbye domain AIP3 PF03915.13 KXZ49224.1 - 0.14 11.2 20.3 0.049 12.7 7.8 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 ERM PF00769.19 KXZ49224.1 - 0.26 11.0 67.8 0.16 11.8 23.6 2.6 2 1 0 2 2 2 0 Ezrin/radixin/moesin family BORCS8 PF10167.9 KXZ49224.1 - 1.9 8.5 5.5 0.92 9.5 1.6 2.4 3 0 0 3 3 2 0 BLOC-1-related complex sub-unit 8 Prominin PF05478.11 KXZ49224.1 - 3.1 5.6 18.0 0.23 9.4 3.5 3.1 2 1 1 3 3 3 0 Prominin GPS2_interact PF15784.5 KXZ49224.1 - 3.5 8.1 10.3 0.17 12.4 2.8 2.5 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Fib_alpha PF08702.10 KXZ49224.1 - 4.7 7.4 18.0 0.24 11.6 3.4 3.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 KXZ49224.1 - 5.4 6.4 35.6 0.13 11.8 8.8 3.4 2 2 1 3 3 3 0 Leucine zipper ATG16 PF08614.11 KXZ49224.1 - 5.8 7.1 75.4 0.022 15.0 17.8 4.5 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) APC_N_CC PF16689.5 KXZ49224.1 - 6.4 6.9 13.6 9.8 6.3 2.6 4.3 3 1 1 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain Scaffolding_pro PF11418.8 KXZ49224.1 - 7.6 7.2 7.9 29 5.3 0.1 3.6 4 0 0 4 4 3 0 Phi29 scaffolding protein Sec34 PF04136.15 KXZ49224.1 - 9.2 6.1 23.6 1.3 8.9 8.3 4.2 4 2 1 5 5 4 0 Sec34-like family Keratin_2_head PF16208.5 KXZ49225.1 - 3.3 7.8 19.9 0.086 13.0 11.4 2.1 2 0 0 2 2 2 0 Keratin type II head Corona_nucleoca PF00937.18 KXZ49226.1 - 0.68 8.9 5.7 1.1 8.2 5.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DIRP PF06584.13 KXZ49229.1 - 2.5e-16 59.8 1.1 3.4e-16 59.3 0.2 1.7 2 0 0 2 2 2 1 DIRP DUF4510 PF14971.6 KXZ49229.1 - 0.032 14.6 4.8 0.051 13.9 1.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4510) HAUS-augmin3 PF14932.6 KXZ49229.1 - 0.7 9.4 7.1 1.2 8.6 7.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC1 PF03109.16 KXZ49230.1 - 9.8e-40 135.4 0.0 2.3e-39 134.3 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXZ49230.1 - 8.5e-05 22.6 1.1 0.035 14.0 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family UQ_con PF00179.26 KXZ49231.1 - 1.1e-28 99.6 0.0 1.6e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXZ49231.1 - 0.031 14.6 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KXZ49231.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Pkinase PF00069.25 KXZ49233.1 - 2.1e-72 243.7 0.0 2.5e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49233.1 - 4e-42 144.3 0.0 5.5e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ49233.1 - 5.8e-09 35.7 0.0 7.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ49233.1 - 1.2e-06 28.0 0.2 2.3e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ49233.1 - 0.00027 21.0 0.4 0.039 13.9 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ49233.1 - 0.0011 17.9 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Chlorophyllase2 PF12740.7 KXZ49234.1 - 6.1e-09 35.2 0.0 8.8e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Armet PF10208.9 KXZ49234.1 - 0.00018 21.4 0.9 0.00029 20.8 0.9 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Abhydrolase_6 PF12697.7 KXZ49234.1 - 0.0025 18.5 5.1 0.0091 16.6 5.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KXZ49234.1 - 0.0029 16.7 0.0 0.0063 15.6 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.13 KXZ49234.1 - 0.071 13.0 0.0 0.071 13.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXZ49234.1 - 0.073 12.7 0.0 0.26 10.9 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 KXZ49234.1 - 0.091 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXZ49234.1 - 0.16 11.2 0.5 0.54 9.5 0.1 2.0 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF812 PF05667.11 KXZ49235.1 - 8.5e-05 21.6 11.1 0.00013 21.1 11.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FUSC PF04632.12 KXZ49235.1 - 0.042 12.4 11.1 0.1 11.1 8.9 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 KXZ49235.1 - 0.19 11.2 13.5 0.26 10.8 13.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 KXZ49235.1 - 0.93 10.0 28.8 1.8 9.1 28.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 KXZ49235.1 - 1.5 8.3 21.3 3 7.2 21.3 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nup54 PF13874.6 KXZ49235.1 - 1.7 8.8 17.5 2.8 8.0 17.5 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.10 KXZ49235.1 - 2.4 8.3 17.9 3.7 7.7 17.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KXZ49235.1 - 3.4 7.0 31.6 5.3 6.3 8.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-C4H2 PF10146.9 KXZ49235.1 - 4 7.7 21.6 0.55 10.5 17.3 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein WDCP PF15390.6 KXZ49235.1 - 7 4.9 10.9 9.6 4.4 10.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family NPV_P10 PF05531.12 KXZ49235.1 - 8.6 6.9 7.8 5.2 7.6 0.9 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Ctr PF04145.15 KXZ49236.1 - 9.7e-24 84.7 2.9 4.1e-23 82.6 2.9 1.9 1 1 0 1 1 1 1 Ctr copper transporter family dCMP_cyt_deam_2 PF08211.12 KXZ49237.1 - 4.9e-38 130.3 2.6 5e-37 127.1 0.3 2.3 3 0 0 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 KXZ49237.1 - 2.4e-14 53.0 0.1 9.7e-11 41.4 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region OTT_1508_deam PF14441.6 KXZ49237.1 - 0.049 13.6 0.4 0.099 12.7 0.4 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase SNAD4 PF18750.1 KXZ49237.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Det1 PF09737.9 KXZ49238.1 - 7.8e-40 137.2 0.0 9e-19 67.8 0.1 3.2 3 0 0 3 3 3 3 De-etiolated protein 1 Det1 Sedlin_N PF04628.13 KXZ49239.1 - 2e-42 144.4 0.0 2.3e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXZ49239.1 - 6.3e-07 29.4 0.0 7.4e-07 29.2 0.0 1.2 1 1 0 1 1 1 1 Sybindin-like family Pkinase PF00069.25 KXZ49240.1 - 2.2e-71 240.3 0.2 3.2e-71 239.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49240.1 - 8.9e-33 113.7 0.1 1.3e-32 113.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 KXZ49240.1 - 4e-28 94.8 9.0 2.3e-06 26.8 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ49240.1 - 5e-28 97.3 3.9 3.5e-13 49.8 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ49240.1 - 1.8e-25 86.6 3.2 2.1e-05 24.1 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXZ49240.1 - 5.1e-21 73.2 9.9 0.00019 20.7 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXZ49240.1 - 1e-19 70.1 9.9 3.7e-11 42.7 0.6 4.0 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXZ49240.1 - 3.1e-06 27.5 0.1 0.02 15.2 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXZ49240.1 - 3.1e-05 23.8 1.6 0.0004 20.3 0.2 2.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KXZ49240.1 - 0.00015 21.9 5.4 0.85 9.9 0.1 3.5 2 1 1 3 3 3 3 Dockerin type I domain EF-hand_9 PF14658.6 KXZ49240.1 - 0.00018 21.8 1.2 0.00094 19.5 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EFhand_Ca_insen PF08726.10 KXZ49240.1 - 0.00029 20.9 0.2 0.0083 16.2 0.0 2.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand APH PF01636.23 KXZ49240.1 - 0.00067 19.7 0.3 0.0068 16.4 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ49240.1 - 0.0033 16.8 0.2 0.01 15.2 0.2 1.9 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ49240.1 - 0.004 16.5 0.1 0.052 12.9 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXZ49240.1 - 0.0083 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF3349 PF11829.8 KXZ49240.1 - 0.012 16.4 0.1 0.041 14.6 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Pox_ser-thr_kin PF05445.11 KXZ49240.1 - 0.11 11.5 0.6 0.15 11.0 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase CxC2 PF18803.1 KXZ49240.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Excalibur PF05901.11 KXZ49240.1 - 1.9 9.2 3.8 1.2 9.8 0.1 2.7 3 0 0 3 3 2 0 Excalibur calcium-binding domain MIR PF02815.19 KXZ49241.1 - 5.7e-21 75.2 0.3 4e-19 69.2 0.1 2.5 1 1 1 2 2 2 2 MIR domain ANAPC4_WD40 PF12894.7 KXZ49241.1 - 0.033 14.5 0.5 0.72 10.2 0.1 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1336 PF07059.12 KXZ49242.1 - 2.8e-46 158.4 0.0 3.4e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) ANAPC10 PF03256.16 KXZ49243.1 - 2.5e-35 121.8 0.0 2.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Nop14 PF04147.12 KXZ49244.1 - 0.099 10.9 11.9 0.14 10.3 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXZ49244.1 - 0.19 10.0 17.1 0.28 9.5 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 KXZ49244.1 - 0.26 9.8 11.6 0.47 9.0 11.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.12 KXZ49244.1 - 0.76 9.0 7.9 1.3 8.3 7.9 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KXZ49244.1 - 1.6 8.2 9.0 2.7 7.5 9.0 1.2 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 KXZ49244.1 - 3.4 8.1 7.9 19 5.7 6.1 3.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 LAP1C PF05609.12 KXZ49244.1 - 4.3 6.3 6.3 6.4 5.8 6.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Pox_Ag35 PF03286.14 KXZ49244.1 - 7.1 6.4 11.6 16 5.2 11.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mpp10 PF04006.12 KXZ49244.1 - 9.3 4.6 16.9 13 4.0 16.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Myc_N PF01056.18 KXZ49244.1 - 9.3 6.0 8.2 17 5.2 8.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Peptidase_M24 PF00557.24 KXZ49245.1 - 8.2e-41 140.0 0.1 1.1e-40 139.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Atg29_N PF18388.1 KXZ49245.1 - 0.17 11.8 0.3 0.4 10.5 0.3 1.6 1 0 0 1 1 1 0 Atg29 N-terminal domain BSP_II PF05432.11 KXZ49245.1 - 0.38 10.4 8.8 0.58 9.8 8.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3391 PF11871.8 KXZ49245.1 - 3 8.4 5.1 0.69 10.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Methyltransf_3 PF01596.17 KXZ49246.1 - 6.2e-63 211.8 0.0 6.9e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXZ49246.1 - 2.9e-14 54.0 0.0 4e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ49246.1 - 2.2e-06 27.5 0.0 2.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ49246.1 - 1.6e-05 25.6 0.0 2.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXZ49246.1 - 0.0058 16.4 0.0 0.011 15.4 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KXZ49246.1 - 0.024 15.3 0.0 0.037 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KXZ49246.1 - 0.042 13.8 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4887 PF16228.5 KXZ49247.1 - 0.06 13.5 10.4 0.1 12.7 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) PET117 PF15786.5 KXZ49248.1 - 7.4e-12 45.4 0.0 9.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Amnionless PF14828.6 KXZ49248.1 - 0.064 12.1 0.0 0.064 12.1 0.0 1.0 1 0 0 1 1 1 0 Amnionless Remorin_C PF03763.13 KXZ49249.1 - 0.13 12.1 0.3 0.18 11.7 0.3 1.1 1 0 0 1 1 1 0 Remorin, C-terminal region HATPase_c PF02518.26 KXZ49250.1 - 1.2e-26 93.4 0.2 3.9e-26 91.8 0.2 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KXZ49250.1 - 6.6e-25 87.4 0.0 2.7e-20 72.6 0.0 2.4 2 0 0 2 2 2 2 PAS domain Response_reg PF00072.24 KXZ49250.1 - 2.6e-22 79.1 0.2 4.6e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXZ49250.1 - 9.7e-18 64.0 0.1 2.6e-17 62.6 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KXZ49250.1 - 2.8e-07 30.5 0.0 9.1e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KXZ49250.1 - 1.6e-06 28.3 0.0 7.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KXZ49250.1 - 1.1e-05 25.6 0.0 6.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KXZ49250.1 - 0.00015 21.7 0.0 0.0013 18.7 0.0 2.5 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 KXZ49250.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ResB PF05140.14 KXZ49250.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 ResB-like family ACT PF01842.25 KXZ49251.1 - 0.071 12.9 0.1 5 7.0 0.0 2.3 2 0 0 2 2 2 0 ACT domain ACT_6 PF13740.6 KXZ49251.1 - 0.13 12.3 0.0 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 ACT domain PAC3 PF10178.9 KXZ49253.1 - 1.1e-20 73.6 0.1 1.5e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 TPR_11 PF13414.6 KXZ49256.1 - 2.5e-07 30.2 2.6 0.015 14.9 0.0 3.8 3 0 0 3 3 3 3 TPR repeat TPR_7 PF13176.6 KXZ49256.1 - 0.0012 18.7 2.6 2.9 8.1 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ49256.1 - 0.0028 17.9 23.8 0.013 15.7 3.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 KXZ49256.1 - 0.019 15.0 2.6 0.18 11.9 0.3 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KXZ49256.1 - 0.041 14.0 27.8 0.11 12.6 0.4 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Glutaminase PF04960.15 KXZ49256.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Glutaminase TPR_1 PF00515.28 KXZ49256.1 - 0.3 11.0 13.5 0.38 10.7 0.3 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ49256.1 - 1.2 9.1 13.9 1.2 9.1 1.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ49256.1 - 7.8 7.4 6.8 1.9e+02 3.0 0.7 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 KXZ49260.1 - 2.2e-22 79.0 0.0 2.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Guanylate_cyc PF00211.20 KXZ49261.1 - 6.9e-45 152.9 0.0 6.2e-44 149.8 0.0 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Trypan_PARP PF05887.11 KXZ49261.1 - 0.009 16.0 1.2 0.009 16.0 1.2 3.5 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.12 KXZ49261.1 - 0.076 12.4 15.6 0.11 11.9 15.6 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 KXZ49261.1 - 1.1 9.0 6.5 1.9 8.3 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPN2_C PF18004.1 KXZ49261.1 - 1.6 8.6 9.6 2.6 7.9 9.6 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 KXZ49261.1 - 2.4 6.4 14.1 3.2 5.9 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KXZ49261.1 - 2.8 5.9 22.6 3.7 5.5 22.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KXZ49261.1 - 3.2 5.8 16.8 4.3 5.4 16.8 1.0 1 0 0 1 1 1 0 Nop14-like family MIF4G_like_2 PF09090.11 KXZ49261.1 - 3.4 7.0 5.1 5 6.5 5.1 1.1 1 0 0 1 1 1 0 MIF4G like FAM176 PF14851.6 KXZ49261.1 - 6.5 6.4 9.5 12 5.5 9.5 1.4 1 0 0 1 1 1 0 FAM176 family PPR_3 PF13812.6 KXZ49262.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Pentatricopeptide repeat domain YqfQ PF14181.6 KXZ49262.1 - 0.26 11.5 2.9 0.58 10.3 2.9 1.5 1 0 0 1 1 1 0 YqfQ-like protein HEAT PF02985.22 KXZ49263.1 - 4.3e-08 32.8 6.3 0.027 14.7 0.5 5.7 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.25 KXZ49263.1 - 1.2e-07 31.4 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.6 KXZ49263.1 - 4.4e-07 30.2 2.5 0.1 13.0 2.2 3.7 1 1 3 4 4 4 3 HEAT repeats Cnd1 PF12717.7 KXZ49263.1 - 4.1e-05 23.7 0.1 0.00038 20.5 0.0 2.1 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 KXZ49263.1 - 5.6e-05 22.6 0.0 9.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Adaptin_N PF01602.20 KXZ49263.1 - 0.044 12.3 0.3 3 6.3 0.1 2.1 1 1 1 2 2 2 0 Adaptin N terminal region DUF3437 PF11919.8 KXZ49263.1 - 0.16 11.9 0.8 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Mon2_C PF16206.5 KXZ49264.1 - 4.9e-34 117.6 0.1 8.5e-26 90.4 0.2 3.3 3 0 0 3 3 3 2 C-terminal region of Mon2 protein Sec7_N PF12783.7 KXZ49264.1 - 5.1e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXZ49264.1 - 0.00037 20.3 0.0 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) HEAT PF02985.22 KXZ49264.1 - 0.2 12.0 5.6 5 7.7 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat Metallophos PF00149.28 KXZ49265.1 - 5.8e-19 69.4 0.1 1.1e-18 68.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 KXZ49266.1 - 4e-58 196.9 0.0 6.7e-58 196.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49266.1 - 1e-27 97.1 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ49266.1 - 0.0045 16.3 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ49266.1 - 0.05 13.5 0.2 0.21 11.5 0.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ49266.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Lactamase_B PF00753.27 KXZ49267.1 - 5.9e-06 26.4 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXZ49267.1 - 0.013 15.1 0.1 0.061 12.8 0.0 2.1 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Metallophos PF00149.28 KXZ49269.1 - 2.9e-19 70.4 0.0 4.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IGPS PF00218.21 KXZ49270.1 - 1.4e-08 34.2 0.0 9.4e-05 21.7 0.0 2.5 1 1 1 2 2 2 2 Indole-3-glycerol phosphate synthase SpoU_sub_bind PF08032.12 KXZ49270.1 - 0.076 13.3 0.0 8 6.8 0.0 2.7 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding DUF1289 PF06945.13 KXZ49271.1 - 0.38 10.6 1.7 0.74 9.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Spc7 PF08317.11 KXZ49271.1 - 0.74 8.6 7.0 0.97 8.2 7.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DNA_repr_REX1B PF14966.6 KXZ49272.1 - 0.12 13.0 0.1 8.9 7.1 0.0 2.3 2 0 0 2 2 2 0 DNA repair REX1-B BAR_3 PF16746.5 KXZ49272.1 - 0.16 11.7 0.5 11 5.6 0.1 2.4 2 1 0 3 3 3 0 BAR domain of APPL family Nucleotid_trans PF03407.16 KXZ49273.1 - 9.6e-10 38.8 0.0 5.4e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase Ribosomal_60s PF00428.19 KXZ49273.1 - 4.6e-05 23.9 0.8 4.6e-05 23.9 0.8 2.7 1 1 1 2 2 2 1 60s Acidic ribosomal protein Spt5_N PF11942.8 KXZ49273.1 - 1.1 10.3 9.2 1.9 9.5 9.2 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal 5_nucleotid_C PF02872.18 KXZ49274.1 - 0.2 11.9 0.4 0.35 11.1 0.4 1.3 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain RSN1_TM PF13967.6 KXZ49275.1 - 1.6e-32 112.5 1.1 2e-32 112.1 1.1 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport HisKA_7TM PF16927.5 KXZ49275.1 - 2.9 7.9 9.5 0.72 9.8 6.1 1.6 1 1 0 2 2 2 0 N-terminal 7TM region of histidine kinase RSN1_7TM PF02714.15 KXZ49276.1 - 6.4e-39 133.9 15.3 9.5e-39 133.3 15.3 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXZ49276.1 - 2.2e-13 50.8 0.0 4.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter ResB PF05140.14 KXZ49277.1 - 9.7e-80 268.7 0.0 8.2e-79 265.6 0.0 1.9 1 1 0 1 1 1 1 ResB-like family DUF2065 PF09838.9 KXZ49277.1 - 0.077 13.0 2.6 0.093 12.8 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Glucan_synthase PF02364.15 KXZ49278.1 - 6.8e-132 441.3 0.8 1.7e-131 440.0 0.8 1.7 1 1 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KXZ49278.1 - 7.4e-08 32.8 1.1 1.6e-06 28.5 1.1 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1296 PF06972.11 KXZ49279.1 - 3.2e-13 49.6 0.1 5.1e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) End_tail_spike PF12219.8 KXZ49280.1 - 0.16 12.0 0.2 0.29 11.2 0.2 1.3 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase zf-MYND PF01753.18 KXZ49281.1 - 1.5e-05 25.0 12.6 4.2e-05 23.5 12.6 1.8 1 0 0 1 1 1 1 MYND finger SET PF00856.28 KXZ49282.1 - 1.7e-10 41.6 0.0 2.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 SET domain Utp11 PF03998.13 KXZ49284.1 - 1.1e-72 244.9 11.5 1.3e-72 244.7 11.5 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KXZ49284.1 - 0.0031 16.9 0.3 0.0049 16.2 0.3 1.4 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 DUF4798 PF16055.5 KXZ49284.1 - 0.034 14.4 5.5 0.034 14.4 5.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4798) Ribosomal_S9 PF00380.19 KXZ49286.1 - 1.3e-31 109.6 0.3 1.5e-31 109.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 5_nucleotid PF05761.14 KXZ49289.1 - 2.6e-38 132.1 0.0 2.9e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family 5_nucleotid PF05761.14 KXZ49290.1 - 2e-34 119.3 0.9 3e-18 66.0 0.0 2.0 1 1 1 2 2 2 2 5' nucleotidase family Hydrolase_like PF13242.6 KXZ49290.1 - 0.046 13.8 0.9 0.077 13.1 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like Gb3_synth PF04572.12 KXZ49291.1 - 3.5e-20 72.5 0.0 7.8e-20 71.4 0.0 1.5 2 0 0 2 2 2 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KXZ49293.1 - 1.5e-12 48.0 0.0 2.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Aldolase_II PF00596.21 KXZ49293.1 - 0.0082 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3972 PF13118.6 KXZ49294.1 - 0.025 15.0 0.4 0.043 14.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Peptidase_M14 PF00246.24 KXZ49296.1 - 2.2e-14 53.9 0.0 4.9e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KXZ49296.1 - 5.5e-13 49.2 0.0 8.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain ATP_bind_3 PF01171.20 KXZ49297.1 - 2.8e-42 144.5 0.0 3.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 KXZ49297.1 - 0.064 13.3 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family WD40_3 PF15911.5 KXZ49298.1 - 6.2e-21 74.2 0.0 6.7e-20 70.9 0.0 2.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXZ49298.1 - 1.6e-14 53.9 13.4 1.1e-07 31.3 0.1 4.6 3 1 0 4 4 4 3 Coatomer WD associated region ANAPC4_WD40 PF12894.7 KXZ49298.1 - 9.4e-11 41.9 2.8 0.015 15.6 0.1 5.5 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KXZ49298.1 - 4.7e-10 39.5 4.1 0.0077 16.1 0.0 4.9 4 1 1 5 5 5 3 Region in Clathrin and VPS TPR_7 PF13176.6 KXZ49298.1 - 0.00082 19.2 25.0 1.1 9.4 0.9 8.2 6 2 1 7 7 7 3 Tetratricopeptide repeat AAA_28 PF13521.6 KXZ49298.1 - 0.026 14.8 1.3 0.47 10.7 0.9 2.5 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KXZ49298.1 - 0.13 13.2 0.5 1.4e+02 3.5 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat DZR PF12773.7 KXZ49298.1 - 0.37 10.9 6.2 6.4 6.9 6.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon ANAPC3 PF12895.7 KXZ49298.1 - 1.5 9.1 20.6 0.54 10.5 0.1 6.3 4 3 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXZ49298.1 - 1.9 8.9 17.7 69 4.0 0.2 7.4 6 1 1 7 7 6 0 Tetratricopeptide repeat Stc1 PF12898.7 KXZ49298.1 - 2.8 8.5 5.2 0.78 10.3 0.9 2.5 3 0 0 3 3 1 0 Stc1 domain TPR_2 PF07719.17 KXZ49298.1 - 3.9 7.8 35.7 4.9 7.5 0.1 9.6 10 1 1 11 11 11 0 Tetratricopeptide repeat PerC PF06069.11 KXZ49298.1 - 4.6 7.6 5.0 7.2 6.9 0.1 3.5 4 0 0 4 4 4 0 PerC transcriptional activator TPR_14 PF13428.6 KXZ49298.1 - 5.8 8.0 25.5 4.6 8.3 0.0 8.2 9 1 0 9 9 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ49298.1 - 8 6.5 21.3 5 7.1 0.4 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4449 PF14613.6 KXZ49299.1 - 0.008 16.3 4.8 0.008 16.3 4.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4449) HAP1_N PF04849.13 KXZ49299.1 - 0.029 13.6 20.7 0.14 11.3 18.4 2.1 1 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF4200 PF13863.6 KXZ49299.1 - 0.12 12.8 22.5 3.4 8.1 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.19 KXZ49299.1 - 0.12 10.2 28.1 0.087 10.6 22.7 2.2 1 1 0 2 2 2 0 Myosin tail BBP1_C PF15272.6 KXZ49299.1 - 0.12 12.2 10.3 0.065 13.1 7.5 1.9 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF4407 PF14362.6 KXZ49299.1 - 0.13 11.5 26.5 4.7 6.5 26.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 KXZ49299.1 - 0.14 11.5 18.8 0.36 10.2 11.6 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KXZ49299.1 - 0.28 12.1 24.0 15 6.6 4.7 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Tho2 PF11262.8 KXZ49299.1 - 0.58 9.3 2.9 1.3 8.2 2.8 1.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF724 PF05266.14 KXZ49299.1 - 0.65 9.8 14.6 0.17 11.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prominin PF05478.11 KXZ49299.1 - 0.8 7.6 2.7 1.2 7.0 2.7 1.2 1 0 0 1 1 1 0 Prominin YabA PF06156.13 KXZ49299.1 - 0.89 10.2 12.9 5.2 7.8 2.3 3.2 2 1 1 3 3 3 0 Initiation control protein YabA PRP9_N PF16958.5 KXZ49299.1 - 0.89 9.6 6.1 1.1 9.3 5.0 1.6 1 1 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus Golgin_A5 PF09787.9 KXZ49299.1 - 1 8.8 21.2 1.2 8.5 18.3 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 Lectin_N PF03954.14 KXZ49299.1 - 1.3 8.8 7.5 0.8 9.4 4.5 2.1 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 KXZ49299.1 - 3.3 7.8 5.7 51 3.9 2.8 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 KXZ49299.1 - 4.5 7.7 7.8 2.1 8.8 3.2 2.3 1 1 0 2 2 2 0 Syntaxin-like protein DUF641 PF04859.12 KXZ49299.1 - 6.2 7.2 15.7 4.2 7.7 2.5 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF3037 PF11236.8 KXZ49299.1 - 6.8 7.2 7.4 10 6.6 1.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) HIP1_clath_bdg PF16515.5 KXZ49299.1 - 7.9 7.2 25.1 2 9.1 6.7 3.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KXZ49299.1 - 8 5.2 23.6 2.6 6.9 14.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 KXZ49299.1 - 8.3 4.9 11.1 0.63 8.6 4.4 1.9 1 1 1 2 2 2 0 AAA domain DivIC PF04977.15 KXZ49300.1 - 0.034 13.9 1.0 0.05 13.4 1.0 1.2 1 0 0 1 1 1 0 Septum formation initiator SET PF00856.28 KXZ49301.1 - 3.5e-10 40.5 0.0 6.4e-09 36.4 0.0 2.0 1 1 1 2 2 2 1 SET domain Response_reg PF00072.24 KXZ49302.1 - 7.2e-07 29.4 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain DUF89 PF01937.19 KXZ49303.1 - 6.1e-31 107.7 0.0 6.9e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 RRM_1 PF00076.22 KXZ49305.1 - 1e-40 137.4 0.1 3.5e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ49305.1 - 4.4e-07 29.9 0.1 0.003 17.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 KXZ49305.1 - 0.00029 20.5 0.2 0.68 9.7 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 KXZ49305.1 - 0.0054 16.3 0.1 0.017 14.7 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXZ49305.1 - 0.032 14.2 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KXZ49305.1 - 0.1 12.7 0.2 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Limkain b1 Trp_Tyr_perm PF03222.13 KXZ49306.1 - 2.9e-48 164.9 23.4 1.7e-33 116.2 10.1 2.1 1 1 1 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 KXZ49306.1 - 1.8e-08 33.5 11.6 7.4e-07 28.2 7.2 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein MaoC_dehydratas PF01575.19 KXZ49306.1 - 0.059 12.9 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 MaoC like domain Acetyltransf_1 PF00583.25 KXZ49307.1 - 8.5e-11 42.1 0.1 1.5e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ49307.1 - 0.0028 17.6 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ49307.1 - 0.0033 17.8 0.3 0.0086 16.5 0.3 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ49307.1 - 0.034 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 KXZ49307.1 - 0.075 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4595 PF15283.6 KXZ49308.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold Neurokinin_B PF03823.14 KXZ49308.1 - 8 6.6 6.1 4.1 7.5 0.1 2.5 2 0 0 2 2 2 0 Neurokinin B HSP20 PF00011.21 KXZ49309.1 - 1.3e-19 70.2 0.4 2.4e-11 43.7 0.0 2.3 1 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXZ49309.1 - 8.6e-08 31.6 0.2 2.2e-07 30.4 0.2 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA TP_methylase PF00590.20 KXZ49311.1 - 1.1e-26 94.1 0.1 1.7e-26 93.5 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases HEAT PF02985.22 KXZ49312.1 - 0.00018 21.5 3.2 0.00024 21.1 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.6 KXZ49312.1 - 0.0013 19.2 13.2 0.057 13.9 0.1 3.6 3 1 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KXZ49312.1 - 0.0058 17.0 2.0 0.013 15.9 0.1 2.2 1 1 1 2 2 2 2 HEAT repeats KORA PF16509.5 KXZ49312.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor PI3_PI4_kinase PF00454.27 KXZ49313.1 - 5.6e-29 101.7 0.0 1.5e-28 100.3 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 KXZ49313.1 - 1.8e-14 53.1 3.9 4.9e-09 35.1 0.0 4.0 3 1 1 4 4 4 3 Serine/threonine-protein kinase smg-1 FATC PF02260.20 KXZ49313.1 - 3.5e-14 52.3 0.2 9.6e-14 50.9 0.2 1.8 1 0 0 1 1 1 1 FATC domain LcrR PF09621.10 KXZ49313.1 - 0.017 14.6 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) Herpes_BLRF2 PF05812.12 KXZ49313.1 - 6 7.0 4.9 1.1 9.4 0.4 2.2 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Cyt-b5 PF00173.28 KXZ49314.1 - 7.8e-10 38.8 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PelD_GGDEF PF16963.5 KXZ49314.1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 PelD GGDEF domain OppC_N PF12911.7 KXZ49315.1 - 0.14 12.2 0.3 0.14 12.2 0.3 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Voltage_CLC PF00654.20 KXZ49316.1 - 1e-59 202.6 42.0 1.4e-59 202.1 34.0 2.5 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KXZ49316.1 - 0.0013 19.2 1.0 0.03 14.8 0.0 2.9 3 0 0 3 3 3 1 CBS domain V-SNARE PF05008.15 KXZ49317.1 - 2.6e-19 69.4 3.8 2.6e-19 69.4 3.8 2.7 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KXZ49317.1 - 9.8e-15 54.6 7.2 1.5e-14 54.0 2.5 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXZ49317.1 - 6.8e-07 29.1 3.5 1.3e-06 28.2 0.2 2.7 1 1 1 3 3 3 1 Sec20 Mer2 PF09074.10 KXZ49317.1 - 0.0022 17.8 5.1 0.0042 16.9 5.1 1.4 1 1 0 1 1 1 1 Mer2 RasGAP_C PF03836.15 KXZ49317.1 - 0.011 15.9 1.4 0.021 14.9 1.4 1.5 1 0 0 1 1 1 0 RasGAP C-terminus Rootletin PF15035.6 KXZ49317.1 - 0.015 15.3 0.9 0.015 15.3 0.9 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion zf-RING_9 PF13901.6 KXZ49317.1 - 0.041 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon BRCA2 PF00634.18 KXZ49317.1 - 0.049 13.3 0.3 5 6.9 0.0 2.6 2 0 0 2 2 2 0 BRCA2 repeat DUF4407 PF14362.6 KXZ49317.1 - 0.12 11.7 4.4 0.16 11.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glycophorin_A PF01102.18 KXZ49317.1 - 0.12 12.6 0.2 0.31 11.3 0.2 1.7 1 0 0 1 1 1 0 Glycophorin A Spectrin PF00435.21 KXZ49317.1 - 0.14 12.7 4.1 0.21 12.1 1.6 2.1 1 1 1 2 2 2 0 Spectrin repeat SOGA PF11365.8 KXZ49317.1 - 0.2 12.8 5.0 2.4 9.4 1.2 2.5 1 1 1 2 2 2 0 Protein SOGA Exonuc_VII_L PF02601.15 KXZ49317.1 - 0.5 9.9 7.9 0.81 9.2 7.8 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 KXZ49317.1 - 0.59 10.6 7.2 0.76 10.2 6.6 1.5 1 1 0 1 1 1 0 Fez1 Muted PF14942.6 KXZ49317.1 - 0.98 9.8 6.0 0.25 11.7 2.0 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Prefoldin PF02996.17 KXZ49317.1 - 1.5 8.7 9.5 10 6.0 0.6 3.4 2 2 2 4 4 4 0 Prefoldin subunit Spc7 PF08317.11 KXZ49317.1 - 1.7 7.4 8.9 18 4.1 0.5 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 KXZ49317.1 - 2.4 7.3 6.8 5 6.3 2.5 2.1 1 1 0 2 2 2 0 TMPIT-like protein TMF_DNA_bd PF12329.8 KXZ49317.1 - 3.3 7.8 13.2 0.29 11.1 2.6 3.3 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 KXZ49317.1 - 4.8 7.7 8.5 5.3 7.6 2.2 2.2 1 1 0 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 KXZ49318.1 - 5.2e-05 23.9 2.7 18 6.4 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat MMR_HSR1 PF01926.23 KXZ49319.1 - 9.4e-14 51.5 0.0 2.5e-12 46.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ49319.1 - 2.5e-06 27.1 0.0 9e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXZ49319.1 - 3.4e-05 23.8 0.0 0.0098 15.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXZ49319.1 - 0.00015 21.3 0.0 0.017 14.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KXZ49319.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KXZ49319.1 - 0.023 14.8 1.2 0.09 12.8 0.1 2.4 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.16 KXZ49319.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 KXZ49319.1 - 0.21 11.8 0.0 2.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain FKBP_C PF00254.28 KXZ49320.1 - 3.5e-17 62.5 0.0 1.8e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PsbQ PF05757.11 KXZ49320.1 - 0.00087 19.1 1.3 0.0012 18.6 1.3 1.2 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) FoP_duplication PF13865.6 KXZ49321.1 - 7.3e-15 55.3 17.6 7.3e-15 55.3 17.6 3.1 1 1 2 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Snf7 PF03357.21 KXZ49322.1 - 1.3e-44 151.8 13.5 1.5e-44 151.6 13.5 1.0 1 0 0 1 1 1 1 Snf7 XhlA PF10779.9 KXZ49322.1 - 0.0011 19.1 2.4 0.012 15.8 0.1 2.5 2 0 0 2 2 2 1 Haemolysin XhlA RE_Bsp6I PF09504.10 KXZ49322.1 - 0.023 14.3 0.3 0.041 13.5 0.2 1.4 1 1 0 1 1 1 0 Bsp6I restriction endonuclease SlyX PF04102.12 KXZ49322.1 - 0.027 15.1 9.6 0.63 10.7 0.2 3.3 3 1 0 4 4 4 0 SlyX Bul1_C PF04426.12 KXZ49322.1 - 0.035 13.5 3.8 0.045 13.2 3.8 1.1 1 0 0 1 1 1 0 Bul1 C terminus Atg14 PF10186.9 KXZ49322.1 - 0.052 12.6 3.0 0.079 12.0 3.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin_2 PF01920.20 KXZ49322.1 - 0.11 12.5 11.2 0.14 12.1 0.2 3.1 2 1 1 3 3 3 0 Prefoldin subunit DUF2203 PF09969.9 KXZ49322.1 - 0.37 11.5 5.8 9 7.0 3.5 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FliJ PF02050.16 KXZ49322.1 - 0.5 10.6 12.2 0.16 12.2 8.4 1.9 1 1 1 2 2 2 0 Flagellar FliJ protein FlxA PF14282.6 KXZ49322.1 - 1.1 9.3 9.4 1.3 9.1 8.0 1.8 1 1 0 1 1 1 0 FlxA-like protein Prefoldin PF02996.17 KXZ49322.1 - 3.4 7.6 11.5 3.1 7.7 1.7 2.9 1 1 1 3 3 3 0 Prefoldin subunit DUF1840 PF08895.11 KXZ49322.1 - 4.5 7.7 10.2 0.29 11.5 0.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1840) LUC7 PF03194.15 KXZ49322.1 - 5.1 6.7 11.5 1.8 8.2 6.9 1.9 1 1 1 2 2 2 0 LUC7 N_terminus Cdh1_DBD_1 PF18196.1 KXZ49322.1 - 5.1 7.4 11.2 0.23 11.8 2.3 2.6 1 1 2 3 3 3 0 Chromodomain helicase DNA-binding domain 1 DUF16 PF01519.16 KXZ49322.1 - 9.5 6.8 10.0 4.5e+02 1.4 9.8 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1802 PF08819.11 KXZ49323.1 - 2.5e-50 170.7 0.1 3e-50 170.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) Nup192 PF11894.8 KXZ49324.1 - 1.7e-42 144.9 0.0 1.5e-18 65.5 0.0 3.3 3 1 0 3 3 3 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 RraA-like PF03737.15 KXZ49325.1 - 9.8e-42 142.7 0.1 1.1e-41 142.5 0.1 1.0 1 0 0 1 1 1 1 Aldolase/RraA Gly_transf_sug PF04488.15 KXZ49327.1 - 2.5e-09 37.6 0.0 4.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 KXZ49327.1 - 4.3e-05 23.7 0.0 0.00049 20.3 0.0 2.2 2 0 0 2 2 2 1 Alpha 1,4-glycosyltransferase conserved region Caps_synth PF05704.12 KXZ49327.1 - 0.0029 17.0 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Ank_2 PF12796.7 KXZ49329.1 - 5e-13 49.4 0.0 0.016 15.8 0.1 4.6 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49329.1 - 1.9e-10 41.1 3.7 2.2 9.0 0.0 7.4 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49329.1 - 6.3e-08 32.3 5.7 2.6 8.9 0.0 8.4 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 KXZ49329.1 - 0.061 13.7 12.2 73 3.9 0.0 7.3 7 2 2 9 9 9 0 Ankyrin repeats (many copies) WD40 PF00400.32 KXZ49330.1 - 2.7e-28 97.6 13.8 9.3e-06 26.3 0.2 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ49330.1 - 1.7e-15 57.1 0.0 0.0002 21.6 0.1 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KXZ49330.1 - 1.2e-12 48.0 0.0 2.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split PD40 PF07676.12 KXZ49330.1 - 0.00019 21.3 0.2 2 8.5 0.1 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXZ49330.1 - 0.019 13.9 0.0 7 5.5 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KXZ49330.1 - 0.04 13.6 0.0 19 5.0 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KXZ49330.1 - 0.046 12.4 0.1 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DPPIV_N PF00930.21 KXZ49330.1 - 0.13 11.0 0.0 45 2.6 0.0 3.0 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region ARS2 PF04959.13 KXZ49331.1 - 1.7e-07 31.9 12.8 1.7e-07 31.9 12.8 2.4 2 1 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 KXZ49331.1 - 8.6e-07 29.1 0.3 2e-06 27.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) Zip PF02535.22 KXZ49333.1 - 1.3e-37 129.8 48.4 1.1e-21 77.5 8.5 4.1 3 1 0 3 3 3 2 ZIP Zinc transporter PGF-CTERM PF18204.1 KXZ49333.1 - 3.4 7.8 7.4 14 5.8 7.4 2.2 1 0 0 1 1 1 0 PGF-CTERM motif 2OG-FeII_Oxy_3 PF13640.6 KXZ49336.1 - 2.6e-16 60.3 0.0 4.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KXZ49336.1 - 1.5e-08 35.1 0.0 2.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3458_C PF17432.2 KXZ49336.1 - 0.018 14.5 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats Pkinase_Tyr PF07714.17 KXZ49337.1 - 6e-52 176.5 0.0 9.8e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49337.1 - 7.3e-40 137.0 0.0 1.1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Reg_prop PF07494.11 KXZ49337.1 - 0.046 13.9 0.0 20 5.8 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller APH PF01636.23 KXZ49337.1 - 0.05 13.5 0.9 0.28 11.1 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family UCR_14kD PF02271.16 KXZ49337.1 - 0.23 11.4 0.4 0.47 10.4 0.4 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit NAD_binding_10 PF13460.6 KXZ49338.1 - 5.4e-24 85.1 0.1 6.1e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXZ49338.1 - 2.4e-09 36.6 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXZ49338.1 - 4e-09 36.4 0.1 5.4e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXZ49338.1 - 6.1e-07 29.1 0.0 8.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXZ49338.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.3 1 1 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 KXZ49338.1 - 0.017 14.3 0.1 0.043 13.0 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXZ49338.1 - 0.018 15.3 0.1 0.025 14.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KXZ49338.1 - 0.039 13.4 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase PNP_UDP_1 PF01048.20 KXZ49339.1 - 2.1e-05 23.9 0.2 5e-05 22.7 0.2 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_4 PF13637.6 KXZ49340.1 - 1.2e-10 41.7 1.1 0.26 11.9 0.0 6.2 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49340.1 - 4.1e-09 35.9 0.0 31 5.6 0.0 8.0 8 0 0 8 8 8 1 Ankyrin repeat Ank_2 PF12796.7 KXZ49340.1 - 5.3e-09 36.5 0.0 0.0061 17.1 0.0 4.5 2 2 5 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ49340.1 - 4.2e-08 33.3 1.1 2 8.8 0.0 6.7 5 2 2 7 7 7 2 Ankyrin repeats (many copies) F-box PF00646.33 KXZ49340.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain Ank_2 PF12796.7 KXZ49341.1 - 3e-07 30.9 5.4 0.0052 17.3 0.1 4.6 3 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49341.1 - 0.00093 19.7 8.8 0.59 10.8 0.1 6.5 3 2 4 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49341.1 - 0.011 16.2 6.5 75 4.4 0.0 6.8 8 0 0 8 8 8 0 Ankyrin repeat F-box-like PF12937.7 KXZ49341.1 - 0.041 13.8 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like DAO PF01266.24 KXZ49342.1 - 1.3e-50 173.0 9.8 7.5e-50 170.5 9.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Ank_2 PF12796.7 KXZ49343.1 - 3e-05 24.5 0.0 0.0057 17.2 0.0 3.0 2 1 2 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ49343.1 - 7.2e-05 22.9 1.4 11 6.9 0.1 6.3 6 1 2 8 8 8 1 Ankyrin repeat Ank_4 PF13637.6 KXZ49343.1 - 0.00045 20.7 0.2 2.6 8.7 0.0 5.1 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Nucleotid_trans PF03407.16 KXZ49344.1 - 9.6e-18 64.9 0.0 1.3e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PG_binding_2 PF08823.11 KXZ49345.1 - 0.15 12.4 0.1 0.69 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Ferritin PF00210.24 KXZ49346.1 - 6.5e-24 84.5 1.8 8.5e-24 84.1 1.8 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KXZ49346.1 - 0.00074 19.9 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Rubrerythrin TPT PF03151.16 KXZ49347.1 - 0.00079 18.9 3.2 0.00095 18.6 3.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Fzo_mitofusin PF04799.13 KXZ49347.1 - 0.042 13.4 1.0 0.057 13.0 1.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region TPT PF03151.16 KXZ49348.1 - 0.0009 18.7 17.0 0.0016 17.9 17.0 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family Pex24p PF06398.11 KXZ49348.1 - 0.066 12.2 0.8 0.066 12.2 0.8 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin GBV-C_env PF12786.7 KXZ49348.1 - 0.4 9.3 7.1 0.54 8.9 7.1 1.3 1 0 0 1 1 1 0 GB virus C genotype envelope DUF4191 PF13829.6 KXZ49348.1 - 2.7 7.3 10.9 3.1 7.1 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1700 PF08006.11 KXZ49348.1 - 9.5 5.7 14.5 12 5.4 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Pkinase_Tyr PF07714.17 KXZ49349.1 - 4.5e-30 104.8 0.0 6e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49349.1 - 9.9e-26 90.7 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ49349.1 - 0.0011 19.0 0.5 0.0021 18.0 0.5 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Patched PF02460.18 KXZ49350.1 - 6.6e-95 318.9 0.0 1.5e-94 317.7 0.0 1.5 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KXZ49350.1 - 1.4e-35 122.4 1.8 1.4e-35 122.4 1.8 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KXZ49350.1 - 3.9e-16 58.9 23.7 1.7e-13 50.2 1.2 2.3 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.19 KXZ49350.1 - 2.4e-08 32.2 14.3 2.4e-08 32.2 14.3 1.8 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Aph-1 PF06105.12 KXZ49351.1 - 2.7e-35 121.8 21.6 3.8e-35 121.4 21.6 1.1 1 0 0 1 1 1 1 Aph-1 protein Tau95 PF09734.9 KXZ49351.1 - 6.6e-20 72.4 0.0 1.3e-19 71.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KXZ49351.1 - 2.6e-14 53.5 0.0 4.2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Tau95 Triple barrel domain Prefoldin PF02996.17 KXZ49352.1 - 1.2e-11 44.6 0.3 2.3e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 Prefoldin subunit Aminotran_4 PF01063.19 KXZ49352.1 - 2e-09 37.6 0.0 3.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV IFT43 PF15305.6 KXZ49353.1 - 3.2e-36 124.5 3.8 4.3e-36 124.1 3.8 1.1 1 0 0 1 1 1 1 Intraflagellar transport protein 43 Asparaginase PF00710.20 KXZ49354.1 - 3e-59 199.8 0.0 5.4e-59 199.0 0.0 1.4 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXZ49354.1 - 2e-18 66.7 0.0 5.1e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain IRK_N PF08466.10 KXZ49354.1 - 0.2 11.8 0.8 0.39 10.9 0.8 1.4 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal RRM_1 PF00076.22 KXZ49355.1 - 2e-20 72.4 0.0 2.9e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ49355.1 - 0.003 17.1 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ49355.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KXZ49355.1 - 0.062 13.5 0.0 2.9 8.1 0.0 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_2 PF04059.12 KXZ49355.1 - 0.17 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif 2 Nup35_RRM_2 PF14605.6 KXZ49355.1 - 0.18 11.8 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase_Tyr PF07714.17 KXZ49357.1 - 5.1e-50 170.2 0.0 9.4e-42 143.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49357.1 - 1.4e-41 142.6 0.0 2.8e-41 141.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49357.1 - 9.3e-05 21.4 0.1 0.00016 20.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ49357.1 - 0.00071 19.0 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CHASE PF03924.13 KXZ49357.1 - 0.004 17.1 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 CHASE domain Sds3 PF08598.11 KXZ49357.1 - 0.037 14.0 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 Sds3-like APH PF01636.23 KXZ49357.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ49358.1 - 1.5e-49 168.6 0.0 2.9e-41 141.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49358.1 - 2.6e-40 138.5 0.0 4.8e-40 137.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49358.1 - 0.00041 19.3 0.1 0.00067 18.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ49358.1 - 0.0035 16.7 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CHASE PF03924.13 KXZ49358.1 - 0.032 14.2 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 CHASE domain Sds3 PF08598.11 KXZ49358.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Sds3-like Atg14 PF10186.9 KXZ49359.1 - 0.0088 15.2 2.5 0.012 14.7 2.5 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KXZ49359.1 - 1.1 9.4 13.1 1.7 8.8 13.1 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Erythro_esteras PF05139.14 KXZ49359.1 - 1.7 8.4 10.4 3.4 7.4 10.4 1.4 1 0 0 1 1 1 0 Erythromycin esterase Complex1_LYR PF05347.15 KXZ49360.1 - 1.7e-16 60.0 0.4 2.1e-16 59.7 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KXZ49360.1 - 1.3e-07 32.1 0.1 1.5e-07 31.9 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 KXZ49360.1 - 1.3e-05 25.8 0.0 1.4e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DHO_dh PF01180.21 KXZ49361.1 - 1.4e-26 93.4 0.0 2.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DUF4179 PF13786.6 KXZ49362.1 - 0.18 12.3 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) PHF5 PF03660.14 KXZ49364.1 - 0.2 11.9 1.9 0.27 11.4 1.9 1.3 1 0 0 1 1 1 0 PHF5-like protein NAD_binding_10 PF13460.6 KXZ49366.1 - 5.9e-31 107.8 4.9 3.9e-16 59.5 1.9 2.5 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 KXZ49366.1 - 1.7e-11 44.1 0.5 3.5e-11 43.1 0.5 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXZ49366.1 - 6.4e-10 38.9 0.1 2.1e-08 33.9 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CIA30 PF08547.12 KXZ49366.1 - 1.3e-09 38.2 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) 3Beta_HSD PF01073.19 KXZ49366.1 - 6.3e-05 22.1 0.4 9.2e-05 21.6 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXZ49366.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXZ49366.1 - 0.0025 17.0 0.1 0.011 14.9 0.1 2.0 3 0 0 3 3 3 1 RmlD substrate binding domain adh_short PF00106.25 KXZ49366.1 - 0.0033 16.9 0.3 0.0087 15.5 0.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_4 PF04669.13 KXZ49366.1 - 0.0083 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis Semialdhyde_dh PF01118.24 KXZ49366.1 - 0.025 15.0 0.2 0.21 12.0 0.1 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXZ49366.1 - 0.059 12.5 0.1 0.22 10.6 0.1 1.9 2 0 0 2 2 2 0 Male sterility protein DUF4054 PF13262.6 KXZ49367.1 - 0.057 13.5 3.1 0.074 13.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Ank_3 PF13606.6 KXZ49368.1 - 0.0017 18.7 0.1 23 6.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXZ49368.1 - 0.0029 18.1 0.0 0.0065 17.0 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ49368.1 - 0.016 15.5 0.2 2.9 8.3 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ49368.1 - 0.045 14.3 0.2 0.56 10.8 0.1 2.3 2 1 0 2 2 2 0 Ankyrin repeats (many copies) TPT PF03151.16 KXZ49370.1 - 0.0067 15.8 1.9 0.0077 15.6 1.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ49370.1 - 0.007 16.5 8.7 0.0095 16.1 8.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family Syntaxin-6_N PF09177.11 KXZ49371.1 - 1.8e-11 44.5 5.3 1.7e-08 34.9 0.0 3.7 2 2 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KXZ49371.1 - 1.2e-09 38.0 7.0 1.5e-09 37.7 1.3 2.8 3 0 0 3 3 2 1 SNARE domain MCU PF04678.13 KXZ49371.1 - 0.0009 19.4 2.9 0.0011 19.1 2.9 1.4 1 1 0 1 1 1 1 Mitochondrial calcium uniporter HrpB7 PF09486.10 KXZ49371.1 - 0.0014 19.1 9.4 0.026 14.9 5.4 2.0 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.12 KXZ49371.1 - 0.0016 18.9 2.0 3.7 8.1 2.6 2.9 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KXZ49371.1 - 0.0038 17.7 2.8 0.0049 17.3 1.6 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF16 YukC PF10140.9 KXZ49371.1 - 0.0039 16.1 2.0 0.013 14.3 0.2 2.1 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC CENP-H PF05837.12 KXZ49371.1 - 0.0069 16.8 7.2 0.0069 16.8 7.2 1.9 1 1 1 2 2 2 1 Centromere protein H (CENP-H) UPF0242 PF06785.11 KXZ49371.1 - 0.0071 16.5 2.6 0.0095 16.1 1.5 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus DUF2207 PF09972.9 KXZ49371.1 - 0.014 14.1 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Laminin_II PF06009.12 KXZ49371.1 - 0.017 15.2 5.2 0.34 10.9 1.7 2.5 1 1 1 3 3 3 0 Laminin Domain II Use1 PF09753.9 KXZ49371.1 - 0.025 14.3 5.9 0.037 13.8 5.9 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 HIP1_clath_bdg PF16515.5 KXZ49371.1 - 0.056 14.1 6.5 0.63 10.7 5.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TRIQK PF15168.6 KXZ49371.1 - 0.063 13.2 0.7 0.16 11.9 0.7 1.7 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Exonuc_VII_L PF02601.15 KXZ49371.1 - 0.077 12.6 7.5 0.23 11.0 7.5 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit MHC_II_beta PF00969.19 KXZ49371.1 - 0.16 12.1 0.5 1.1 9.4 0.0 2.3 2 1 1 3 3 3 0 Class II histocompatibility antigen, beta domain Sec20 PF03908.13 KXZ49371.1 - 0.19 11.6 3.8 0.42 10.6 1.7 2.3 1 1 0 2 2 2 0 Sec20 Filament PF00038.21 KXZ49371.1 - 0.2 11.2 7.9 2.9 7.4 6.8 2.1 1 1 1 2 2 2 0 Intermediate filament protein T3SSipB PF16535.5 KXZ49371.1 - 0.31 11.5 8.6 0.095 13.2 4.1 2.1 1 1 0 2 2 2 0 Type III cell invasion protein SipB SlyX PF04102.12 KXZ49371.1 - 0.32 11.6 8.3 0.72 10.5 3.2 3.2 2 2 1 3 3 3 0 SlyX DUF4164 PF13747.6 KXZ49371.1 - 0.32 11.3 9.1 11 6.4 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 KXZ49371.1 - 0.39 11.1 5.9 1.6 9.1 0.3 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) V-SNARE_C PF12352.8 KXZ49371.1 - 0.41 11.0 7.0 0.28 11.5 1.6 3.0 3 1 1 4 4 3 0 Snare region anchored in the vesicle membrane C-terminus KxDL PF10241.9 KXZ49371.1 - 0.77 10.1 6.2 3.7 7.9 0.7 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein Spc7 PF08317.11 KXZ49371.1 - 1 8.2 9.2 2.7 6.8 6.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein MscS_porin PF12795.7 KXZ49371.1 - 1.1 8.7 16.3 2.3 7.7 8.3 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Mod_r PF07200.13 KXZ49371.1 - 1.2 9.3 7.8 1.4 9.0 5.7 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.9 KXZ49371.1 - 1.2 8.1 7.4 6.3 5.8 7.4 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 KXZ49371.1 - 1.3 9.3 8.4 32 4.8 1.1 3.3 2 1 1 3 3 3 0 Haemolysin XhlA T2SSF PF00482.23 KXZ49371.1 - 1.6 8.7 10.1 43 4.1 10.1 2.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F APG6_N PF17675.1 KXZ49371.1 - 1.7 9.2 8.7 0.77 10.3 6.0 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region TBCA PF02970.16 KXZ49371.1 - 1.8 8.9 7.8 2.8 8.3 5.1 2.3 1 1 2 3 3 3 0 Tubulin binding cofactor A DUF2570 PF10828.8 KXZ49371.1 - 5.2 6.9 9.9 2.1 8.2 2.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) Flagellin_N PF00669.20 KXZ49371.1 - 6.8 6.8 11.3 0.21 11.7 1.5 2.7 2 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region DUF150 PF02576.17 KXZ49372.1 - 9.5e-05 22.7 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 RimP N-terminal domain Ge1_WD40 PF16529.5 KXZ49372.1 - 0.069 12.1 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LRR19-TM PF15176.6 KXZ49372.1 - 1.8 8.6 3.8 3.3 7.8 3.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Prothymosin PF03247.14 KXZ49372.1 - 1.9 9.0 18.4 2.9 8.4 18.4 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family RNA_pol_3_Rpc31 PF11705.8 KXZ49372.1 - 3 8.0 17.4 4.4 7.5 17.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Guanylate_cyc PF00211.20 KXZ49373.1 - 4.1e-43 147.1 0.0 7e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SelP_N PF04592.14 KXZ49373.1 - 5.9 6.2 9.3 9 5.6 9.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ribosomal_L32e PF01655.18 KXZ49374.1 - 3.5e-50 168.9 1.2 4.3e-50 168.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase_Tyr PF07714.17 KXZ49376.1 - 5.6e-39 134.0 0.0 2e-35 122.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49376.1 - 5.7e-37 127.5 0.0 2.4e-31 109.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49376.1 - 7e-05 21.8 0.0 8.8e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ49376.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Clathrin_lg_ch PF01086.17 KXZ49377.1 - 2.5e-10 40.8 0.0 8e-10 39.2 0.0 1.9 2 1 0 2 2 2 1 Clathrin light chain TBCC PF07986.12 KXZ49377.1 - 5.5e-06 26.1 0.0 7.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C PRIMA1 PF16101.5 KXZ49378.1 - 0.071 13.1 11.7 0.36 10.9 7.0 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KXZ49378.1 - 9.3 6.3 5.9 1.2 9.1 1.1 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator His_Phos_1 PF00300.22 KXZ49379.1 - 1.6e-11 44.3 0.5 3.9e-06 26.7 0.3 3.0 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Ammonium_transp PF00909.21 KXZ49380.1 - 7.6e-73 245.5 24.1 9.2e-73 245.2 24.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family NPL4 PF05021.15 KXZ49382.1 - 4e-21 75.7 0.0 2.1e-12 47.0 0.0 2.4 2 1 0 2 2 2 2 NPL4 family UN_NPL4 PF11543.8 KXZ49382.1 - 1.5e-10 41.4 0.0 1.7e-09 38.0 0.0 2.6 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 JAB PF01398.21 KXZ49382.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UQ_con PF00179.26 KXZ49383.1 - 2.5e-48 163.3 0.0 2.8e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXZ49383.1 - 0.0015 18.3 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXZ49383.1 - 0.0028 17.9 0.1 0.0042 17.3 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KXZ49383.1 - 0.0081 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain AAA_22 PF13401.6 KXZ49384.1 - 1.5e-06 28.5 0.0 0.0029 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXZ49384.1 - 1.9e-06 28.4 4.4 3.2e-06 27.6 1.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXZ49384.1 - 7.8e-05 23.1 0.0 0.56 10.6 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KXZ49384.1 - 0.00083 19.4 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA lid domain Cdc6_C PF09079.11 KXZ49384.1 - 0.0078 16.2 0.0 0.077 13.0 0.0 2.3 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_33 PF13671.6 KXZ49384.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXZ49384.1 - 0.078 12.2 0.0 0.89 8.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KXZ49384.1 - 0.14 12.0 0.2 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KXZ49384.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase THOC2_N PF16134.5 KXZ49384.1 - 0.32 9.6 1.2 0.48 9.0 1.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Glyco_transf_49 PF13896.6 KXZ49385.1 - 2.9e-31 109.0 0.0 1.4e-15 57.5 0.0 2.9 2 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan DNA_primase_lrg PF04104.14 KXZ49386.1 - 2.1e-70 237.2 0.0 3.5e-70 236.4 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Myb_DNA-binding PF00249.31 KXZ49386.1 - 0.011 15.9 0.0 0.38 11.0 0.0 3.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain Pkinase_Tyr PF07714.17 KXZ49388.1 - 9.6e-16 57.8 0.0 2.2e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49388.1 - 2.3e-14 53.4 0.0 3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ49388.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ49388.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Mpp10 PF04006.12 KXZ49389.1 - 4.4e-08 32.1 0.0 4.8e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 Mpp10 protein Pkinase_Tyr PF07714.17 KXZ49390.1 - 2.9e-17 62.8 0.0 4.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49390.1 - 2.1e-15 56.8 0.0 3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain MYO10_CC PF16735.5 KXZ49390.1 - 0.031 14.4 0.8 0.068 13.3 0.8 1.5 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Kdo PF06293.14 KXZ49390.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MgtE_N PF03448.17 KXZ49391.1 - 1.2e-15 57.9 0.0 0.00053 20.5 0.0 5.3 2 2 2 5 5 5 4 MgtE intracellular N domain FliG_N PF14842.6 KXZ49391.1 - 1.9e-10 41.2 7.3 0.02 15.4 0.1 6.7 4 2 1 6 6 6 3 FliG N-terminal domain FliG_M PF14841.6 KXZ49391.1 - 0.0091 16.2 1.2 49 4.2 0.0 5.0 4 2 2 6 6 6 0 FliG middle domain DUF4332 PF14229.6 KXZ49391.1 - 0.32 11.2 1.7 2.7 8.3 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4332) Imm49 PF15575.6 KXZ49393.1 - 0.82 9.4 6.9 0.069 12.9 1.8 1.8 2 0 0 2 2 2 0 Immunity protein 49 Pkinase PF00069.25 KXZ49395.1 - 1.8e-34 119.3 0.0 2.8e-32 112.2 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49395.1 - 3.9e-34 118.1 0.2 4.9e-30 104.7 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ49395.1 - 0.014 15.3 0.1 0.014 15.3 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sulfotransfer_3 PF13469.6 KXZ49396.1 - 2e-08 34.9 0.1 0.0029 18.0 0.1 2.3 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KXZ49396.1 - 5.6e-06 26.0 0.0 3.9e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Med26 PF08711.11 KXZ49398.1 - 1.2e-11 44.4 0.1 2.1e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.25 KXZ49399.1 - 2.1e-65 220.8 0.0 2.5e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49399.1 - 1.3e-29 103.3 0.0 1.8e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49399.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Metallophos PF00149.28 KXZ49400.1 - 1.6e-43 149.6 0.0 2e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXZ49400.1 - 1e-22 80.3 0.9 2.1e-22 79.3 0.9 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pro_isomerase PF00160.21 KXZ49401.1 - 2.1e-26 93.1 0.0 2.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SoxY PF13501.6 KXZ49401.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY MetOD2 PF18548.1 KXZ49401.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Metanogen output domain 2 PseudoU_synth_1 PF01416.20 KXZ49402.1 - 9.1e-12 45.4 0.0 2e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.25 KXZ49403.1 - 9.7e-23 80.9 0.0 1.6e-19 70.3 0.0 2.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49403.1 - 2.9e-22 79.2 0.0 1.7e-16 60.3 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49403.1 - 0.00062 18.7 0.0 0.00099 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49403.1 - 0.018 14.9 2.1 0.054 13.4 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ49404.1 - 9.5e-46 156.3 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49404.1 - 4.8e-24 85.0 0.0 6e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ49404.1 - 0.00018 20.9 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ49404.1 - 0.0068 15.2 0.0 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49404.1 - 0.016 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ49404.1 - 0.016 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXZ49404.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Aa_trans PF01490.18 KXZ49405.1 - 9.8e-49 166.1 12.0 1.4e-48 165.6 12.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ldh_1_C PF02866.18 KXZ49405.1 - 6.2e-34 117.3 0.0 1.2e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXZ49405.1 - 7.8e-24 84.4 0.1 1.8e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 KXZ49405.1 - 0.023 14.6 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain PsbN PF02468.15 KXZ49405.1 - 2.3 8.1 5.4 0.75 9.7 0.6 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) TFIIA PF03153.13 KXZ49406.1 - 0.072 13.1 7.0 0.13 12.3 7.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 KXZ49406.1 - 0.085 12.5 0.7 1.4 8.5 0.7 2.2 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SMN PF06003.12 KXZ49406.1 - 0.8 8.9 11.2 2.2 7.4 11.2 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Spt20 PF12090.8 KXZ49406.1 - 2.3 7.8 9.9 3.3 7.3 9.9 1.1 1 0 0 1 1 1 0 Spt20 family Guanylate_cyc PF00211.20 KXZ49407.1 - 2.9e-54 183.5 0.0 4.6e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RIX1 PF08167.12 KXZ49407.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Kelch_1 PF01344.25 KXZ49410.1 - 2.7e-28 97.3 15.3 3.3e-09 36.2 0.2 6.5 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KXZ49410.1 - 4.3e-28 97.1 4.2 1.5e-09 37.7 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ49410.1 - 1.2e-25 88.9 3.8 1.5e-06 28.3 0.0 6.6 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KXZ49410.1 - 1.8e-22 78.8 4.9 0.00022 21.1 0.3 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KXZ49410.1 - 1.7e-21 76.0 10.7 4.3e-06 26.9 0.0 5.4 6 0 0 6 6 4 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KXZ49410.1 - 6e-19 67.2 3.2 0.00018 21.4 0.0 5.6 6 0 0 6 6 6 3 Kelch motif ACBP PF00887.19 KXZ49410.1 - 9.8e-18 64.2 0.2 2.7e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein Macoilin PF09726.9 KXZ49410.1 - 0.0066 15.1 11.0 0.0092 14.6 11.0 1.1 1 0 0 1 1 1 1 Macoilin family DUF4763 PF15960.5 KXZ49410.1 - 0.027 13.8 3.2 0.046 13.0 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Rootletin PF15035.6 KXZ49410.1 - 0.028 14.5 7.2 0.053 13.6 7.2 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FAM76 PF16046.5 KXZ49410.1 - 0.14 11.5 3.3 0.23 10.8 3.3 1.3 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 KXZ49410.1 - 0.18 10.6 14.3 0.27 10.1 14.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_HK97_TLTM PF06120.11 KXZ49410.1 - 0.19 10.9 7.2 0.29 10.3 7.2 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Baculo_PEP_C PF04513.12 KXZ49410.1 - 0.2 11.7 1.4 0.34 11.0 1.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KXZ49410.1 - 0.29 10.4 19.1 0.46 9.8 19.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KXZ49410.1 - 0.34 10.9 12.7 0.64 10.0 12.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 KXZ49410.1 - 1.1 8.8 9.7 4.2 6.8 9.7 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit GAS PF13851.6 KXZ49410.1 - 1.3 8.3 13.2 2 7.7 13.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KXZ49410.1 - 1.9 8.9 12.6 7.2 7.0 9.4 2.1 1 1 1 2 2 2 0 Fez1 FlxA PF14282.6 KXZ49410.1 - 3.5 7.7 13.2 9.1 6.3 8.4 2.4 1 1 1 2 2 2 0 FlxA-like protein Myosin_tail_1 PF01576.19 KXZ49410.1 - 4.3 5.0 19.2 6.2 4.5 19.2 1.1 1 0 0 1 1 1 0 Myosin tail DUF4201 PF13870.6 KXZ49410.1 - 7.7 6.2 9.0 3.4 7.4 6.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF493 PF04359.14 KXZ49411.1 - 6.9e-17 61.8 0.0 7.9e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF493) Guanylate_cyc PF00211.20 KXZ49412.1 - 7.9e-55 185.3 0.0 1.3e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 KXZ49412.1 - 0.031 14.5 0.0 15 5.9 0.0 3.1 3 0 0 3 3 3 0 PAS fold Peptidase_C97 PF05903.14 KXZ49413.1 - 1.9e-13 50.5 0.1 1e-11 44.9 0.0 2.2 1 1 1 2 2 2 2 PPPDE putative peptidase domain LRAT PF04970.13 KXZ49413.1 - 0.061 13.6 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase NTP_transferase PF00483.23 KXZ49415.1 - 3.7e-73 246.2 0.0 5.8e-73 245.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KXZ49415.1 - 0.0017 18.7 0.0 0.0036 17.7 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KXZ49415.1 - 0.0062 16.2 13.9 0.071 12.9 2.5 3.7 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ49415.1 - 0.33 10.8 10.8 6 6.7 3.3 3.5 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Erg28 PF03694.13 KXZ49416.1 - 5e-09 36.5 3.3 1.8e-07 31.5 0.6 2.1 1 1 1 2 2 2 2 Erg28 like protein Chloroa_b-bind PF00504.21 KXZ49418.1 - 0.017 15.7 0.0 0.019 15.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyll A-B binding protein EGF_2 PF07974.13 KXZ49419.1 - 0.0049 17.2 11.9 0.0049 17.2 11.9 3.1 3 0 0 3 3 3 1 EGF-like domain TPR_MLP1_2 PF07926.12 KXZ49420.1 - 0.00018 21.6 9.1 0.00018 21.6 9.1 7.4 2 2 4 6 6 6 2 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 KXZ49420.1 - 0.00031 20.5 28.5 0.003 17.3 1.0 5.6 2 1 2 5 5 5 2 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 KXZ49420.1 - 0.0045 17.0 61.0 0.14 12.1 5.2 6.5 2 2 4 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KXZ49420.1 - 0.008 16.2 16.2 3.2 7.8 0.8 5.9 4 2 3 7 7 7 2 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.12 KXZ49420.1 - 0.009 15.8 0.4 0.009 15.8 0.4 5.0 5 0 0 5 5 4 1 Viral A-type inclusion protein repeat Filament PF00038.21 KXZ49420.1 - 0.0099 15.5 64.3 0.045 13.3 2.5 5.4 1 1 4 5 5 5 4 Intermediate filament protein Spc7 PF08317.11 KXZ49420.1 - 0.03 13.2 72.7 0.0074 15.2 10.8 5.3 1 1 5 6 6 6 0 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 KXZ49420.1 - 0.15 12.0 0.1 0.15 12.0 0.1 6.1 4 3 4 8 8 8 0 Bacteriophage Mu Gam like protein WD40 PF00400.32 KXZ49420.1 - 0.28 12.1 4.8 37 5.4 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Fez1 PF06818.15 KXZ49420.1 - 0.29 11.6 60.2 0.65 10.4 19.1 4.2 1 1 2 3 3 3 0 Fez1 IFT57 PF10498.9 KXZ49420.1 - 0.54 9.2 18.0 0.17 10.9 1.3 3.1 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 AMP-binding PF00501.28 KXZ49420.1 - 3.6 6.1 7.2 0.33 9.5 0.6 2.2 2 0 0 2 2 2 0 AMP-binding enzyme GAS PF13851.6 KXZ49420.1 - 5 6.4 50.4 2.3 7.5 1.0 5.2 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KXZ49420.1 - 6.4 6.9 9.7 11 6.2 0.5 4.0 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.9 KXZ49420.1 - 8.5 6.6 18.6 0.077 13.3 0.4 3.4 2 2 1 3 3 3 0 Zinc finger-containing protein Pkinase_Tyr PF07714.17 KXZ49421.1 - 6.1e-19 68.3 0.0 2.2e-17 63.2 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49421.1 - 8e-19 68.0 0.0 2.1e-17 63.4 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49421.1 - 5.3e-06 25.5 0.0 7.6e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ49421.1 - 0.04 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ49423.1 - 1e-21 77.4 0.0 1.8e-19 70.0 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49423.1 - 1.9e-20 73.4 0.0 7.4e-18 64.9 0.0 3.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49423.1 - 9.1e-06 24.7 0.0 1.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ49423.1 - 0.063 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ49424.1 - 1.1e-20 74.1 0.0 5.4e-19 68.5 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49424.1 - 3e-19 69.4 0.0 5.6e-17 62.0 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KXZ49424.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ PF00595.24 KXZ49426.1 - 0.0057 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KXZ49426.1 - 0.014 15.2 0.3 0.041 13.7 0.3 1.9 1 0 0 1 1 1 0 PDZ domain Choline_kinase PF01633.20 KXZ49428.1 - 3.5e-48 164.0 0.0 6.2e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KXZ49428.1 - 1.6e-15 57.7 4.1 1.3e-11 44.9 1.8 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ49430.1 - 2.2e-34 119.0 0.0 1.3e-32 113.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49430.1 - 3.3e-30 105.2 0.0 3.2e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49430.1 - 0.0034 16.2 0.0 0.0045 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49430.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family WSC PF01822.19 KXZ49431.1 - 3.1e-10 40.1 0.3 5.2e-10 39.4 0.3 1.4 1 0 0 1 1 1 1 WSC domain SBP_bac_6 PF13343.6 KXZ49432.1 - 2.8e-07 30.2 0.0 0.0026 17.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein EF-hand_7 PF13499.6 KXZ49433.1 - 1.7e-15 57.2 2.7 1.4e-09 38.3 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ49433.1 - 7.3e-11 40.8 7.1 0.0002 20.7 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KXZ49433.1 - 3.5e-08 32.7 8.2 0.0011 18.7 0.2 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KXZ49433.1 - 4.5e-07 29.6 4.3 0.0022 17.8 0.5 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KXZ49433.1 - 0.036 14.4 0.2 0.1 12.9 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 KXZ49433.1 - 0.1 12.1 1.6 3.9 7.1 0.1 3.1 3 0 0 3 3 3 0 EF hand Peptidase_M11 PF05548.11 KXZ49434.1 - 4.4e-29 101.6 1.4 6.1e-29 101.2 1.4 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 VHS PF00790.19 KXZ49435.1 - 7.6e-20 71.2 0.1 1.2e-19 70.5 0.1 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KXZ49435.1 - 0.018 15.3 0.1 0.053 13.8 0.1 1.8 1 0 0 1 1 1 0 GAT domain DUF572 PF04502.13 KXZ49435.1 - 0.38 10.3 5.4 0.72 9.4 5.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.13 KXZ49435.1 - 2.3 8.1 14.8 3.2 7.6 14.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_UL25 PF01499.16 KXZ49435.1 - 8.4 4.8 11.7 12 4.2 11.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Abhydrolase_1 PF00561.20 KXZ49437.1 - 1.3e-22 80.7 0.1 1.8e-21 76.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ49437.1 - 1.8e-12 48.3 2.6 2.5e-12 47.9 2.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ49437.1 - 7.9e-12 44.9 0.3 6.1e-11 42.0 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXZ49437.1 - 0.00016 20.5 0.0 0.00023 20.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KXZ49437.1 - 0.0041 16.8 0.1 0.0063 16.2 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 KXZ49437.1 - 0.0062 16.3 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KXZ49437.1 - 0.0098 15.8 1.0 2.5 7.9 0.1 2.2 2 0 0 2 2 2 2 Serine hydrolase PGAP1 PF07819.13 KXZ49437.1 - 0.016 15.0 0.2 0.025 14.3 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 KXZ49437.1 - 0.018 15.1 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Acyl_transf_1 PF00698.21 KXZ49437.1 - 0.15 11.5 0.6 0.23 10.9 0.6 1.3 1 0 0 1 1 1 0 Acyl transferase domain DUF915 PF06028.11 KXZ49437.1 - 0.22 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PRA1 PF03208.19 KXZ49438.1 - 0.17 11.5 5.5 0.24 11.0 5.5 1.2 1 0 0 1 1 1 0 PRA1 family protein 2TM PF13239.6 KXZ49438.1 - 0.48 10.8 3.3 0.32 11.3 1.8 1.6 2 0 0 2 2 2 0 2TM domain CorA PF01544.18 KXZ49439.1 - 4.5e-07 29.5 0.6 7e-07 28.9 0.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4321 PF14209.6 KXZ49439.1 - 0.31 10.9 0.7 0.53 10.2 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) Phosducin PF02114.16 KXZ49440.1 - 2.6e-17 62.7 0.0 4.9e-17 61.8 0.0 1.3 1 1 0 1 1 1 1 Phosducin LepB_GAP_C PF18227.1 KXZ49440.1 - 0.041 14.4 0.0 0.095 13.2 0.0 1.6 1 0 0 1 1 1 0 LepB GAP domain C-terminal subdomain LRR_6 PF13516.6 KXZ49441.1 - 4.2e-10 38.8 6.2 2.9e-05 23.8 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 KXZ49441.1 - 3.5e-05 23.8 0.2 11 7.0 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 KXZ49441.1 - 0.11 12.3 2.7 12 5.7 0.2 4.6 5 0 0 5 5 5 0 Leucine rich repeat UbiA PF01040.18 KXZ49442.1 - 8.3e-19 67.9 9.6 1e-18 67.6 9.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Radial_spoke_3 PF06098.11 KXZ49444.1 - 3.3e-108 361.3 3.4 3.3e-108 361.3 3.4 2.3 2 0 0 2 2 2 1 Radial spoke protein 3 E1_DerP2_DerF2 PF02221.15 KXZ49446.1 - 2.6e-07 31.1 0.0 3.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ML domain DNA_ligase_aden PF01653.18 KXZ49447.1 - 8e-48 163.1 0.0 2e-42 145.4 0.0 2.2 1 1 1 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 KXZ49447.1 - 2.6e-28 97.7 0.5 6.7e-28 96.4 0.5 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain Nudix_N_2 PF14803.6 KXZ49447.1 - 0.11 12.5 0.9 1.6 8.7 2.4 2.1 2 0 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.11 KXZ49447.1 - 0.32 10.7 2.8 5.1 6.8 2.8 2.3 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain AA_permease_2 PF13520.6 KXZ49449.1 - 5e-41 140.9 23.3 6.1e-41 140.6 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXZ49449.1 - 8.8e-16 57.5 19.9 4.8e-15 55.1 19.9 1.9 1 1 0 1 1 1 1 Amino acid permease DUF2358 PF10184.9 KXZ49450.1 - 6.9e-13 48.9 0.0 9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KXZ49450.1 - 4.9e-06 27.1 0.3 8.7e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.25 KXZ49451.1 - 5.9e-14 52.1 0.0 1e-11 44.7 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49451.1 - 3.3e-06 26.6 0.1 0.0032 16.8 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ49451.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PDEase_I PF00233.19 KXZ49452.1 - 1.7e-67 227.6 0.0 2.4e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Peptidase_S28 PF05577.12 KXZ49452.1 - 3.2e-61 207.5 0.0 4.5e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 KXZ49452.1 - 0.00088 19.0 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXZ49452.1 - 0.0019 17.7 0.1 0.0038 16.7 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 KXZ49452.1 - 0.0035 16.1 0.1 0.0057 15.4 0.1 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 KXZ49452.1 - 0.0079 15.5 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXZ49452.1 - 0.16 11.8 0.0 0.69 9.7 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Linker_histone PF00538.19 KXZ49453.1 - 1.2e-20 73.7 0.0 2.6e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family SLC12 PF03522.15 KXZ49453.1 - 9.3 5.1 15.6 15 4.5 15.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 DUF5320 PF17253.2 KXZ49454.1 - 0.51 11.4 19.3 0.098 13.7 2.1 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Fmp27_WPPW PF10359.9 KXZ49454.1 - 0.93 8.3 9.4 1.1 8.1 7.4 1.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Macoilin PF09726.9 KXZ49454.1 - 2.4 6.6 24.2 0.08 11.5 17.5 1.7 2 0 0 2 2 2 0 Macoilin family DUF572 PF04502.13 KXZ49454.1 - 3.6 7.1 20.2 1.1 8.8 17.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) LCD1 PF09798.9 KXZ49454.1 - 4.8 5.6 13.5 7 5.0 13.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Pkinase PF00069.25 KXZ49455.1 - 4.2e-63 213.2 0.0 5.8e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49455.1 - 3.5e-44 151.0 0.0 5.3e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ49455.1 - 1.1e-05 25.0 0.1 3.5e-05 23.3 0.0 1.9 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KXZ49455.1 - 0.00011 21.2 0.1 0.00018 20.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXZ49455.1 - 0.0011 19.0 2.9 1.9 8.4 0.0 3.7 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KXZ49455.1 - 0.028 13.8 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SUIM_assoc PF16619.5 KXZ49455.1 - 3.2 7.9 12.0 0.18 11.9 2.5 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 COX5B PF01215.19 KXZ49456.1 - 4.2e-07 29.7 0.0 1.1e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Vb SOUL PF04832.12 KXZ49458.1 - 1.6e-43 148.8 0.0 1.1e-40 139.5 0.0 2.0 1 1 0 1 1 1 1 SOUL heme-binding protein GyrI-like PF06445.15 KXZ49458.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 GyrI-like small molecule binding domain BRCA2 PF00634.18 KXZ49459.1 - 7.6e-13 47.9 12.1 0.0003 20.4 0.0 4.1 5 0 0 5 5 5 3 BRCA2 repeat BRCA-2_OB1 PF09103.10 KXZ49460.1 - 1e-27 96.5 0.0 1.4e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KXZ49460.1 - 1.4e-14 54.1 0.0 2.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 BRCA2, helical Pkinase_Tyr PF07714.17 KXZ49462.1 - 2.1e-42 145.2 0.0 3.2e-33 115.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49462.1 - 2.7e-39 135.1 0.0 8.2e-30 104.0 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain APH PF01636.23 KXZ49462.1 - 0.0057 16.6 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ49462.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ49463.1 - 3.6e-55 187.2 0.0 4.4e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49463.1 - 2.2e-25 89.5 0.0 2.9e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIX PF18529.1 KXZ49463.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins ABATE PF07336.11 KXZ49463.1 - 6.1 7.5 6.3 59 4.3 0.2 2.6 1 1 1 2 2 2 0 Putative stress-induced transcription regulator RRM_1 PF00076.22 KXZ49464.1 - 6.4e-25 86.8 0.2 2.7e-12 46.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ49464.1 - 2.3e-12 46.6 0.0 4.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ49464.1 - 0.00091 19.0 0.0 0.096 12.6 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 KXZ49464.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) AMP-binding PF00501.28 KXZ49465.1 - 1.1e-101 340.5 0.0 1.3e-101 340.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ49465.1 - 1.2e-05 26.2 0.5 0.00025 22.0 0.2 3.1 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain Pkinase_Tyr PF07714.17 KXZ49466.1 - 2e-43 148.5 0.0 1.1e-37 129.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49466.1 - 4e-38 131.3 0.0 2.6e-30 105.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49466.1 - 0.00028 19.8 0.0 0.00037 19.4 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49466.1 - 0.0037 17.2 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ49466.1 - 0.043 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ49466.1 - 0.052 12.8 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like DUF4680 PF15730.5 KXZ49466.1 - 5.7 7.3 5.2 10 6.4 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) FAST_1 PF06743.15 KXZ49467.1 - 7e-07 29.1 2.5 0.075 13.0 0.0 4.4 4 1 3 7 7 7 5 FAST kinase-like protein, subdomain 1 Astro_capsid_p PF12226.8 KXZ49468.1 - 1.9 7.6 5.8 3 6.9 5.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SGT1 PF07093.11 KXZ49468.1 - 9.4 4.5 4.8 13 4.1 4.8 1.1 1 0 0 1 1 1 0 SGT1 protein Npa1 PF11707.8 KXZ49469.1 - 3.4e-28 99.0 0.0 7e-28 98.0 0.0 1.6 1 1 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KXZ49469.1 - 8.5e-19 67.9 0.0 6.4e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 SBF_like PF13593.6 KXZ49470.1 - 3.6e-46 157.9 15.8 4.2e-46 157.7 15.8 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KXZ49470.1 - 7.9e-15 55.0 3.1 7.9e-15 55.0 3.1 2.3 2 1 0 2 2 2 1 Sodium Bile acid symporter family Haspin_kinase PF12330.8 KXZ49471.1 - 6.7e-47 160.2 0.0 9.1e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain XET_C PF06955.12 KXZ49471.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus APH PF01636.23 KXZ49471.1 - 0.052 13.5 0.1 0.052 13.5 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Aminotran_1_2 PF00155.21 KXZ49472.1 - 8.7e-52 176.5 0.0 1.2e-34 120.0 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II DUF5308 PF17233.2 KXZ49472.1 - 0.13 12.5 0.2 0.13 12.5 0.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Rif1_N PF12231.8 KXZ49473.1 - 4.3e-09 35.8 0.0 5.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal FoP_duplication PF13865.6 KXZ49473.1 - 5.4 7.6 12.7 3.3 8.3 2.4 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 p25-alpha PF05517.12 KXZ49475.1 - 3.4e-28 98.8 3.2 1.3e-27 96.9 3.2 1.7 1 1 0 1 1 1 1 p25-alpha DBR1 PF05011.13 KXZ49477.1 - 4.5e-29 101.6 0.0 6.9e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KXZ49477.1 - 4.6e-09 37.1 0.1 8.3e-09 36.2 0.1 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ49477.1 - 0.0091 16.2 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 KXZ49478.1 - 1.1e-42 146.3 0.0 1.6e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49478.1 - 8.9e-41 139.9 0.0 1.3e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ49478.1 - 9.2e-05 22.5 0.5 0.00019 21.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4253 PF14062.6 KXZ49478.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Haspin_kinase PF12330.8 KXZ49478.1 - 0.19 10.7 0.2 1 8.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain DUF3038 PF11237.8 KXZ49479.1 - 0.0037 17.3 0.2 0.0091 16.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3038) DUF3636 PF12331.8 KXZ49480.1 - 0.00091 19.1 0.7 0.007 16.2 0.1 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3636) DUF383 PF04063.14 KXZ49480.1 - 0.054 13.2 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF383) ORC5_C PF14630.6 KXZ49483.1 - 0.15 11.5 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF4265 PF14085.6 KXZ49484.1 - 0.059 13.3 0.1 1.5 8.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4265) ACP_PD PF04336.12 KXZ49484.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase HrpB_C PF08482.10 KXZ49485.1 - 3.6e-45 153.6 0.0 7.7e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal DUF3446 PF11928.8 KXZ49485.1 - 0.024 15.0 14.0 0.024 15.0 14.0 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain DsrD PF08679.11 KXZ49485.1 - 0.16 12.2 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) DEAD PF00270.29 KXZ49486.1 - 0.0012 18.7 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KXZ49486.1 - 0.0022 18.4 0.0 0.0029 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ49486.1 - 0.0048 16.6 0.1 0.0072 16.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ49486.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF3638 PF12340.8 KXZ49486.1 - 0.056 12.8 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) ResIII PF04851.15 KXZ49486.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KXZ49486.1 - 0.15 12.0 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 KXZ49486.1 - 0.16 12.2 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain JAB PF01398.21 KXZ49487.1 - 4e-17 62.3 0.0 6.5e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KXZ49487.1 - 4.4e-17 62.3 0.0 7.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KXZ49487.1 - 4.8e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CSTF2_hinge PF14327.6 KXZ49489.1 - 4.7e-19 68.6 1.3 4.7e-19 68.6 1.3 3.0 2 2 1 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KXZ49489.1 - 6e-15 54.8 0.4 1.3e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KXZ49489.1 - 6.9e-13 48.0 10.1 2e-12 46.5 10.1 1.9 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal partial_CstF PF15861.5 KXZ49489.1 - 0.16 11.8 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain TRAPPC-Trs85 PF12739.7 KXZ49490.1 - 5.8e-64 216.5 0.0 1.2e-58 199.1 0.0 2.1 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 KXZ49490.1 - 0.0057 14.1 0.0 0.008 13.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit EMP70 PF02990.16 KXZ49491.1 - 4.1e-163 543.8 18.0 5.2e-163 543.5 18.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4064 PF13273.6 KXZ49491.1 - 5.4 7.3 19.1 3 8.2 1.1 3.9 3 2 0 3 3 3 0 Protein of unknown function (DUF4064) Rad51 PF08423.11 KXZ49492.1 - 8.1e-40 136.7 0.0 1e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KXZ49492.1 - 6.6e-11 42.1 0.4 1.3e-10 41.1 0.4 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KXZ49492.1 - 1.7e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 KXZ49492.1 - 6.8e-06 26.4 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KXZ49492.1 - 0.00042 19.7 0.1 0.014 14.8 0.1 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 KXZ49492.1 - 0.00043 19.8 0.3 0.046 13.2 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_16 PF13191.6 KXZ49492.1 - 0.0037 17.7 0.4 0.0079 16.6 0.4 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXZ49492.1 - 0.0052 17.3 0.1 0.0091 16.5 0.1 1.5 1 1 0 1 1 1 1 ABC transporter Flavokinase PF01687.17 KXZ49493.1 - 1.2e-29 102.8 0.0 1.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Methyltransf_25 PF13649.6 KXZ49493.1 - 0.00066 20.3 0.0 0.0017 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ49493.1 - 0.0012 19.5 0.0 0.0027 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ49493.1 - 0.007 16.2 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Lact-deh-memb PF09330.11 KXZ49493.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding LysM PF01476.20 KXZ49494.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 LysM domain TPR_11 PF13414.6 KXZ49495.1 - 6.7e-13 48.1 7.1 1.8e-05 24.3 0.0 5.3 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.17 KXZ49495.1 - 1.7e-12 46.4 9.3 0.0048 16.9 0.7 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ49495.1 - 1.6e-10 40.4 3.9 0.0079 16.3 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ49495.1 - 4e-10 40.2 17.9 5.5e-07 30.1 0.4 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ49495.1 - 1.8e-09 38.0 12.5 2.9e-05 24.5 0.8 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ49495.1 - 4.1e-09 35.9 4.8 0.039 13.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ49495.1 - 2e-08 34.3 27.1 0.016 16.0 5.2 6.4 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ49495.1 - 4.1e-06 26.4 5.6 0.4 10.8 0.5 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ49495.1 - 7.8e-06 25.9 0.1 3.1 8.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ49495.1 - 7.7e-05 22.8 1.2 7.7e-05 22.8 1.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ49495.1 - 0.0004 20.6 10.9 0.073 13.4 1.3 3.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ49495.1 - 0.0032 18.0 16.0 1.7 9.4 0.4 6.7 7 1 0 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 KXZ49495.1 - 0.067 13.3 7.8 2.3 8.3 0.5 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KXZ49495.1 - 0.071 13.0 14.8 0.4 10.6 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KXZ49495.1 - 0.17 12.0 0.6 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit TPR_4 PF07721.14 KXZ49495.1 - 0.26 12.0 0.1 0.26 12.0 0.1 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Sel1 PF08238.12 KXZ49495.1 - 0.48 11.2 4.4 0.27 12.0 0.8 2.7 2 0 0 2 2 1 0 Sel1 repeat ASH PF15780.5 KXZ49496.1 - 1.9e-58 194.8 49.1 0.00015 21.9 0.0 29.0 31 2 2 33 33 33 14 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KXZ49496.1 - 2.2e-30 104.7 14.6 0.053 13.4 0.0 19.0 19 1 1 20 20 20 9 MSP (Major sperm protein) domain PapD-like PF14874.6 KXZ49496.1 - 8e-30 103.0 12.5 0.0042 17.2 0.0 14.1 15 0 0 15 15 15 8 Flagellar-associated PapD-like DUF1573 PF07610.11 KXZ49496.1 - 3.1e-16 59.2 0.0 17 5.5 0.0 16.9 19 0 0 19 19 19 2 Protein of unknown function (DUF1573) DUF5001 PF16392.5 KXZ49496.1 - 4.9e-09 36.0 1.0 0.022 14.6 0.0 8.1 7 0 0 7 7 7 1 Ig-like domain TMEM131_like PF12371.8 KXZ49496.1 - 1.3e-07 31.8 11.7 0.29 11.4 0.0 10.9 13 1 1 14 14 14 3 Transmembrane protein 131-like fn3_5 PF06280.12 KXZ49496.1 - 1.8e-07 31.9 10.4 8.6 7.1 0.0 11.6 13 0 0 13 13 13 1 Fn3-like domain MYCBPAP PF14646.6 KXZ49496.1 - 2.9e-07 29.8 0.0 4.3 6.2 0.0 9.0 11 1 1 12 12 12 1 MYCBP-associated protein family Rhodanese PF00581.20 KXZ49496.1 - 8.3e-05 23.1 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_M11 PF05548.11 KXZ49497.1 - 3.9e-105 351.5 7.5 5.3e-105 351.0 7.5 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 ORC5_C PF14630.6 KXZ49498.1 - 5e-40 137.8 0.0 9e-40 137.0 0.0 1.4 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus Thioredoxin PF00085.20 KXZ49503.1 - 1.1e-23 83.2 0.1 1.5e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ49503.1 - 5.7e-06 26.7 0.1 4.7e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ49503.1 - 0.00035 20.9 0.0 0.00077 19.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXZ49503.1 - 0.0011 19.1 0.2 0.0026 17.9 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KXZ49503.1 - 0.0025 17.7 0.1 0.0037 17.2 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KXZ49503.1 - 0.015 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 KXZ49503.1 - 0.029 13.7 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_5 PF13743.6 KXZ49503.1 - 0.089 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 KXZ49503.1 - 0.13 12.0 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin PF00085.20 KXZ49504.1 - 2.2e-26 91.8 0.0 2.6e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ49504.1 - 2.9e-08 34.1 0.1 1.4e-07 31.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KXZ49504.1 - 9.1e-07 29.0 0.1 1.4e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KXZ49504.1 - 1.1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KXZ49504.1 - 0.00028 20.8 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KXZ49504.1 - 0.00089 18.7 0.0 0.00092 18.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KXZ49504.1 - 0.0038 16.9 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KXZ49504.1 - 0.0066 16.2 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 KXZ49504.1 - 0.046 13.9 0.1 0.089 13.0 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin PRK PF00485.18 KXZ49505.1 - 3.5e-80 268.4 0.0 1.2e-79 266.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF3828 PF12883.7 KXZ49505.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) ubiquitin PF00240.23 KXZ49506.1 - 3.2e-11 42.8 0.8 3.9e-11 42.5 0.8 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXZ49506.1 - 9.8e-05 22.1 0.5 0.00012 21.8 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ApoB100_C PF12491.8 KXZ49506.1 - 0.0016 18.3 0.8 0.0033 17.3 0.8 1.5 1 1 0 1 1 1 1 Apolipoprotein B100 C terminal Ubiquitin_2 PF14560.6 KXZ49506.1 - 0.01 16.3 0.1 0.014 15.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Longin PF13774.6 KXZ49507.1 - 6.9e-24 83.7 0.1 1.1e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXZ49507.1 - 3.2e-18 65.3 0.3 3.2e-18 65.3 0.3 1.6 2 0 0 2 2 2 1 Synaptobrevin DotU PF09850.9 KXZ49507.1 - 0.09 12.5 0.0 12 5.6 0.0 2.1 2 0 0 2 2 2 0 Type VI secretion system protein DotU DUF2924 PF11149.8 KXZ49507.1 - 0.11 12.9 1.1 0.19 12.1 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) Rad21_Rec8_N PF04825.13 KXZ49508.1 - 9.1e-18 64.4 0.2 1.7e-17 63.6 0.2 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXZ49508.1 - 1.6e-11 43.3 0.0 3.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Pkinase PF00069.25 KXZ49510.1 - 8.9e-70 235.1 0.0 1.9e-54 184.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49510.1 - 6.6e-37 127.2 0.0 1.1e-31 110.1 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KXZ49510.1 - 0.002 18.1 1.4 0.075 12.9 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ49510.1 - 0.018 14.4 0.0 0.059 12.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KXZ49510.1 - 0.041 13.5 0.0 5 6.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Reticulon PF02453.17 KXZ49512.1 - 7.4e-09 35.7 0.5 1.4e-07 31.6 0.5 2.3 1 1 0 1 1 1 1 Reticulon FAM117 PF15388.6 KXZ49512.1 - 0.16 11.4 0.3 0.25 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein Family FAM117 Ank_2 PF12796.7 KXZ49513.1 - 2.6e-06 27.9 0.0 0.00063 20.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ49513.1 - 5.3e-05 23.3 0.0 0.25 12.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXZ49513.1 - 0.0031 17.9 0.0 4.8 7.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat V-SNARE_C PF12352.8 KXZ49514.1 - 5.2e-12 45.9 0.8 3.9e-11 43.1 0.3 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXZ49514.1 - 7.6e-05 22.5 0.2 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 Sec20 Tweety PF04906.13 KXZ49514.1 - 0.017 13.8 0.2 0.056 12.1 0.0 1.7 2 0 0 2 2 2 0 Tweety COX7B PF05392.11 KXZ49514.1 - 0.035 13.8 0.1 0.7 9.6 0.0 2.7 3 0 0 3 3 3 0 Cytochrome C oxidase chain VIIB T3SS_basalb_I PF17001.5 KXZ49514.1 - 0.13 12.9 1.3 15 6.3 0.2 2.4 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI BssS PF13991.6 KXZ49514.1 - 0.29 11.2 0.9 0.93 9.6 0.2 2.0 2 0 0 2 2 2 0 BssS protein family YojJ PF10372.9 KXZ49514.1 - 0.34 11.0 0.9 1.3 9.1 0.2 2.3 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus MscS_porin PF12795.7 KXZ49514.1 - 9.8 5.6 11.3 1.4 8.4 3.6 2.4 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain UDPGP PF01704.18 KXZ49515.1 - 0.00049 18.9 0.0 0.00093 17.9 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase RINGv PF12906.7 KXZ49516.1 - 0.00038 20.5 12.5 0.0007 19.7 12.5 1.5 1 0 0 1 1 1 1 RING-variant domain CAP_N PF01213.19 KXZ49516.1 - 4.2 6.8 12.5 0.75 9.2 5.6 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KXZ49516.1 - 4.2 7.4 9.5 0.28 11.2 3.6 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.25 KXZ49517.1 - 6.6e-57 192.9 0.0 8.8e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49517.1 - 8.5e-33 113.7 0.0 1.1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ49517.1 - 0.0012 18.8 0.3 0.021 14.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ49517.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KXZ49517.1 - 0.086 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KXZ49517.1 - 0.17 11.5 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SF1-HH PF16275.5 KXZ49518.1 - 1.7e-24 86.3 0.8 1.7e-24 86.3 0.8 2.7 4 0 0 4 4 4 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KXZ49518.1 - 1.9e-09 37.2 0.1 4.4e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 KH domain RRM_1 PF00076.22 KXZ49518.1 - 0.00013 21.7 0.1 0.00036 20.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDHD PF02862.17 KXZ49518.1 - 0.72 10.0 2.7 6.9 6.8 0.1 2.8 3 0 0 3 3 3 0 DDHD domain DSBA PF01323.20 KXZ49519.1 - 2.5e-36 125.3 0.1 2.8e-36 125.1 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXZ49519.1 - 3.9e-05 23.9 0.0 0.0029 17.8 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KXZ49519.1 - 0.01 15.9 0.0 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_2 PF13098.6 KXZ49519.1 - 0.11 13.0 0.2 2.7 8.5 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain Lipase_3 PF01764.25 KXZ49520.1 - 7.4e-29 100.4 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2062 PF09835.9 KXZ49520.1 - 0.011 15.7 1.0 0.047 13.6 1.0 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Lipase_GDSL_2 PF13472.6 KXZ49521.1 - 0.043 14.2 0.2 0.36 11.2 0.0 2.5 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family SRCR PF00530.18 KXZ49522.1 - 9.6e-12 45.3 0.3 3.4e-07 30.7 0.1 4.0 3 1 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ49522.1 - 3.4e-05 24.3 0.0 0.00029 21.3 0.0 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Ank_2 PF12796.7 KXZ49524.1 - 1.6e-26 92.7 1.3 4.3e-07 30.4 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ49524.1 - 2.2e-20 72.5 9.1 6.6e-07 29.5 0.2 5.7 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49524.1 - 3.4e-16 57.7 8.8 0.034 14.7 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat Ank_4 PF13637.6 KXZ49524.1 - 6.2e-16 58.5 8.7 0.01 16.4 0.0 6.5 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49524.1 - 1.5e-08 34.7 21.7 1.3 9.6 0.1 8.9 10 0 0 10 10 10 4 Ankyrin repeat TUG-UBL1 PF11470.8 KXZ49524.1 - 1.2e-05 25.4 0.1 0.061 13.6 0.0 2.4 2 0 0 2 2 2 2 TUG ubiquitin-like domain AAA_22 PF13401.6 KXZ49525.1 - 0.0025 18.1 0.0 3 8.1 0.0 4.3 4 0 0 4 4 4 1 AAA domain DDE_Tnp_IS66_C PF13817.6 KXZ49525.1 - 0.0047 17.1 0.4 0.065 13.5 0.0 3.1 2 0 0 2 2 2 1 IS66 C-terminal element UPF0149 PF03695.13 KXZ49525.1 - 0.47 10.7 0.0 0.47 10.7 0.0 4.6 4 1 1 5 5 5 0 Uncharacterised protein family (UPF0149) DUF1614 PF07758.11 KXZ49527.1 - 0.054 13.5 1.2 0.2 11.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1614) Nucleotid_trans PF03407.16 KXZ49532.1 - 6e-14 52.5 0.0 8.8e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Rad21_Rec8_N PF04825.13 KXZ49532.1 - 1.1e-11 44.9 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein APOBEC_N PF08210.11 KXZ49532.1 - 0.11 12.4 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Auxin_repressed PF05564.12 KXZ49532.1 - 1.9 9.2 4.6 22 5.8 4.7 2.5 2 1 0 2 2 2 0 Dormancy/auxin associated protein AAA_22 PF13401.6 KXZ49533.1 - 0.17 12.1 0.0 1 9.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain ICMT PF04140.14 KXZ49534.1 - 0.012 16.0 0.2 0.057 13.8 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXZ49534.1 - 0.035 14.5 0.7 0.099 13.1 0.1 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase GCV_T PF01571.21 KXZ49535.1 - 2.4e-10 40.3 0.0 0.00027 20.4 0.0 2.5 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KXZ49535.1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF4407 PF14362.6 KXZ49535.1 - 0.44 9.9 8.3 0.62 9.4 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 KXZ49535.1 - 3.3 8.2 8.2 0.13 12.7 1.6 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3707 PF12499.8 KXZ49536.1 - 5.2e-40 137.3 21.9 5.5e-20 72.4 8.0 2.6 2 0 0 2 2 2 2 Pherophorin Lectin_C PF00059.21 KXZ49537.1 - 0.15 12.8 24.3 9.8 7.0 0.0 7.1 5 3 2 7 7 7 0 Lectin C-type domain Abhydrolase_6 PF12697.7 KXZ49540.1 - 2.5e-11 44.6 7.4 3e-11 44.4 7.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ49540.1 - 2e-07 30.9 0.7 2.6e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ49540.1 - 1.8e-06 27.4 0.0 2.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXZ49540.1 - 0.002 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KXZ49540.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Pkinase PF00069.25 KXZ49542.1 - 5.5e-25 88.2 0.0 1.8e-21 76.7 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49542.1 - 1.8e-24 86.5 0.0 3.3e-13 49.5 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Branch PF02485.21 KXZ49542.1 - 1.4e-17 64.0 0.0 2.1e-16 60.2 0.0 2.1 1 1 0 1 1 1 1 Core-2/I-Branching enzyme DEAD PF00270.29 KXZ49542.1 - 4e-07 30.0 0.0 7.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ49542.1 - 6.8e-05 23.2 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_pol_A PF00476.20 KXZ49542.1 - 0.00022 20.4 0.0 0.0016 17.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family A HHH_5 PF14520.6 KXZ49542.1 - 0.13 12.9 0.1 0.37 11.4 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain NOG1_N PF17835.1 KXZ49543.1 - 3.2e-24 85.7 0.0 4.8e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KXZ49543.1 - 8.5e-19 67.1 0.0 1.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KXZ49543.1 - 1.6e-16 60.4 0.0 3.7e-16 59.2 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ49543.1 - 4.4e-10 39.3 0.0 7.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXZ49543.1 - 0.014 15.3 0.3 0.14 12.0 0.1 2.7 2 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KXZ49543.1 - 0.047 13.7 0.0 0.54 10.3 0.0 2.4 1 1 0 1 1 1 0 Dynamin family Gtr1_RagA PF04670.12 KXZ49543.1 - 0.24 10.7 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KXZ49543.1 - 0.52 10.7 4.6 0.38 11.1 0.9 2.6 1 1 1 2 2 2 0 AAA ATPase domain FIST PF08495.10 KXZ49546.1 - 4.6e-14 52.8 1.5 4.7e-12 46.3 1.5 2.7 1 1 0 1 1 1 1 FIST N domain FIST_C PF10442.9 KXZ49546.1 - 5e-07 29.7 0.0 2e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 FIST C domain Cwf_Cwc_15 PF04889.12 KXZ49546.1 - 0.12 12.0 5.4 0.27 11.0 1.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 KXZ49546.1 - 1.9 8.3 6.8 3.1 7.6 6.8 1.3 1 0 0 1 1 1 0 SPX domain CENP-B_dimeris PF09026.10 KXZ49546.1 - 6.6 7.2 11.4 2.3 8.7 3.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ADH_zinc_N PF00107.26 KXZ49547.1 - 9.6e-13 48.2 0.1 1.5e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXZ49547.1 - 2.5e-05 24.1 0.0 0.00021 21.2 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXZ49547.1 - 0.0037 18.3 0.1 0.017 16.2 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXZ49547.1 - 0.029 13.8 0.4 0.17 11.3 1.6 1.7 2 0 0 2 2 2 0 short chain dehydrogenase TrkA_N PF02254.18 KXZ49547.1 - 0.05 13.9 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 KXZ49549.1 - 3e-31 108.8 0.0 2.3e-28 99.3 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49549.1 - 2.1e-29 102.6 0.0 3.1e-14 52.9 0.0 4.0 4 0 0 4 4 4 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49549.1 - 0.0004 19.3 0.0 0.00058 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49549.1 - 0.015 15.2 0.2 0.084 12.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ49549.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ49550.1 - 5.1e-30 104.7 0.0 2.4e-27 96.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49550.1 - 2e-29 102.7 0.0 1.7e-14 53.8 0.0 4.0 4 0 0 4 4 4 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49550.1 - 0.00048 19.0 0.0 0.00073 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49550.1 - 0.028 14.3 1.2 0.08 12.8 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ49550.1 - 0.19 11.1 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ49551.1 - 1.8e-25 89.8 0.0 3.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49551.1 - 1.9e-21 76.5 0.0 4.7e-20 72.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KXZ49551.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HisG_C PF08029.11 KXZ49552.1 - 3.5e-14 52.7 0.0 6.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain HisG PF01634.18 KXZ49552.1 - 7.9e-06 25.9 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase PP2C PF00481.21 KXZ49553.1 - 5.5e-73 245.8 0.1 5.5e-57 193.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C HisG PF01634.18 KXZ49554.1 - 6.9e-23 81.4 0.0 9.9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase NTP_transf_2 PF01909.23 KXZ49555.1 - 2.3e-07 31.0 0.0 5.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain NIF PF03031.18 KXZ49555.1 - 0.0007 19.4 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PAP_assoc PF03828.19 KXZ49555.1 - 0.00092 19.4 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KXZ49555.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Form_Nir_trans PF01226.17 KXZ49556.1 - 2.4e-66 223.5 32.3 2.8e-66 223.2 32.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter NIR_SIR PF01077.22 KXZ49557.1 - 9e-52 174.8 0.0 2.1e-36 124.8 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KXZ49557.1 - 2e-37 126.9 0.0 5.1e-18 64.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain MFS_1 PF07690.16 KXZ49558.1 - 4.3e-22 78.5 40.3 4.3e-22 78.5 40.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NAR2 PF16974.5 KXZ49559.1 - 1.1e-07 31.4 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 High-affinity nitrate transporter accessory Ldh_1_N PF00056.23 KXZ49560.1 - 7.7e-36 123.3 0.0 1.1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXZ49560.1 - 4.3e-31 108.1 0.0 6.5e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain PIH1 PF08190.12 KXZ49561.1 - 7e-23 80.9 0.0 3e-20 72.3 0.0 2.5 2 0 0 2 2 2 2 PIH1 N-terminal domain PIH1_CS PF18201.1 KXZ49561.1 - 5.3e-18 65.3 0.0 9.9e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain Dynamin_N PF00350.23 KXZ49564.1 - 3.1e-19 69.7 0.0 3.5e-18 66.2 0.0 2.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXZ49564.1 - 1.2e-16 60.8 2.6 3e-16 59.5 2.6 1.6 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 KXZ49564.1 - 1.1e-05 25.5 6.6 4.2e-05 23.6 0.5 3.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXZ49564.1 - 0.00035 20.6 0.2 0.5 10.5 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase Baculo_PEP_C PF04513.12 KXZ49564.1 - 0.017 15.2 0.1 0.062 13.3 0.1 2.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RsbRD_N PF14361.6 KXZ49564.1 - 0.038 14.7 0.8 1.8 9.3 0.1 3.2 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain YojJ PF10372.9 KXZ49564.1 - 0.038 14.1 0.4 0.17 12.0 0.3 2.2 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus TniB PF05621.11 KXZ49564.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein T3SS_needle_F PF09392.10 KXZ49564.1 - 0.081 13.1 2.0 16 5.7 0.5 3.4 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF AAA_16 PF13191.6 KXZ49564.1 - 0.35 11.2 2.5 1.2 9.5 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain PP2C_C PF07830.13 KXZ49564.1 - 1.3 9.5 3.2 37 4.9 0.2 3.8 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Asp_protease_2 PF13650.6 KXZ49565.1 - 0.0019 18.8 0.0 0.005 17.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXZ49565.1 - 0.013 16.0 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TFIIF_alpha PF05793.12 KXZ49565.1 - 0.043 12.4 29.9 0.06 11.9 29.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PTPRCAP PF15713.5 KXZ49565.1 - 1.5 9.1 38.4 0.47 10.7 34.4 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Trypan_PARP PF05887.11 KXZ49565.1 - 4.9 7.1 29.1 14 5.6 29.1 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rieske_2 PF13806.6 KXZ49566.1 - 4.3e-19 68.4 0.0 9.1e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain LRR_4 PF12799.7 KXZ49566.1 - 6e-18 64.7 19.3 5.6e-07 29.8 0.5 4.1 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ49566.1 - 1.1e-12 47.5 15.2 3.4e-07 29.9 7.5 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KXZ49566.1 - 2.3e-11 43.5 0.4 6.4e-09 35.6 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat Rieske PF00355.26 KXZ49566.1 - 7.4e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain LRR_6 PF13516.6 KXZ49566.1 - 0.56 10.4 6.4 48 4.4 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat S10_plectin PF03501.15 KXZ49569.1 - 3.6e-44 148.8 0.2 4.2e-44 148.5 0.2 1.0 1 0 0 1 1 1 1 Plectin/S10 domain TFIIE_alpha PF02002.17 KXZ49569.1 - 0.12 12.2 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Glyco_trans_2_3 PF13632.6 KXZ49570.1 - 0.00064 19.7 0.2 0.0012 18.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXZ49570.1 - 0.0072 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Amino_oxidase PF01593.24 KXZ49573.1 - 5.8e-20 72.0 12.4 1.2e-11 44.6 6.3 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DEK_C PF08766.11 KXZ49573.1 - 9.7e-11 41.4 0.3 9.7e-11 41.4 0.3 2.2 2 0 0 2 2 2 1 DEK C terminal domain NAD_binding_8 PF13450.6 KXZ49573.1 - 9.1e-10 38.6 0.7 9.1e-10 38.6 0.7 3.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXZ49573.1 - 9.5e-06 25.0 0.3 9.5e-06 25.0 0.3 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXZ49573.1 - 9.8e-06 25.0 1.1 2.8e-05 23.5 1.1 1.8 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXZ49573.1 - 1.1e-05 25.9 1.9 8e-05 23.1 0.6 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ49573.1 - 3.3e-05 23.3 7.0 6.7e-05 22.3 0.3 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ49573.1 - 0.00016 20.5 2.8 0.00017 20.4 1.0 1.9 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KXZ49573.1 - 0.00049 19.4 1.8 0.00049 19.4 1.8 2.1 3 0 0 3 3 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXZ49573.1 - 0.0013 17.9 2.2 0.0013 17.9 2.2 1.9 2 0 0 2 2 1 1 Glucose inhibited division protein A SWIRM PF04433.17 KXZ49573.1 - 0.0047 17.3 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Lycopene_cycl PF05834.12 KXZ49573.1 - 0.01 14.9 1.1 0.024 13.7 1.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXZ49573.1 - 0.38 10.0 9.0 0.04 13.2 0.9 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXZ49573.1 - 1.8 8.5 5.1 6.5 6.7 0.3 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Myb_DNA-binding PF00249.31 KXZ49574.1 - 6.5e-09 35.9 0.0 9.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain EPL1 PF10513.9 KXZ49574.1 - 0.24 11.8 3.1 0.12 12.7 0.8 1.7 2 0 0 2 2 2 0 Enhancer of polycomb-like Roughex PF06020.11 KXZ49574.1 - 2.2 7.3 10.2 0.11 11.6 0.8 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Spt20 PF12090.8 KXZ49574.1 - 2.3 7.8 18.0 0.46 10.1 11.9 2.2 2 0 0 2 2 2 0 Spt20 family TPR_MLP1_2 PF07926.12 KXZ49576.1 - 0.0013 18.8 14.1 0.0013 18.8 14.1 2.2 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein EzrA PF06160.12 KXZ49576.1 - 0.009 14.2 2.2 0.012 13.9 2.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 KXZ49576.1 - 0.015 15.3 12.5 0.63 10.1 7.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GRDP-like PF07173.12 KXZ49576.1 - 0.025 15.3 1.7 0.04 14.6 1.7 1.3 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like Golgin_A5 PF09787.9 KXZ49576.1 - 0.038 13.5 10.7 0.055 12.9 10.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 MscS_porin PF12795.7 KXZ49576.1 - 0.071 12.7 23.9 0.1 12.2 23.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Tropomyosin PF00261.20 KXZ49576.1 - 0.11 11.9 16.3 0.16 11.3 15.3 1.7 1 1 1 2 2 2 0 Tropomyosin Atg14 PF10186.9 KXZ49576.1 - 0.18 10.8 11.3 0.22 10.6 11.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SAS4 PF15460.6 KXZ49576.1 - 0.27 11.4 4.5 3.1 7.9 0.0 2.7 1 1 2 3 3 3 0 Something about silencing, SAS, complex subunit 4 DUF745 PF05335.13 KXZ49576.1 - 0.38 10.5 21.7 0.63 9.7 21.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 KXZ49576.1 - 0.51 9.9 13.9 0.65 9.5 13.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 KXZ49576.1 - 0.65 8.8 12.6 0.85 8.4 12.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein NEMO PF11577.8 KXZ49576.1 - 0.82 9.7 15.0 0.21 11.6 4.9 3.3 2 2 1 3 3 3 0 NF-kappa-B essential modulator NEMO Lzipper-MIP1 PF14389.6 KXZ49576.1 - 0.89 9.9 9.6 3.9 7.8 9.6 2.2 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4200 PF13863.6 KXZ49576.1 - 1.1 9.7 21.7 1 9.8 9.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) YabA PF06156.13 KXZ49576.1 - 1.3 9.7 10.2 0.25 12.0 0.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 KXZ49576.1 - 1.4 8.2 18.8 1.9 7.8 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 KXZ49576.1 - 1.7 7.9 6.1 2.1 7.6 6.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FapA PF03961.13 KXZ49576.1 - 2.1 6.8 3.7 4.2 5.9 3.8 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 KXZ49576.1 - 6.9 6.8 24.3 22 5.2 24.3 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF5401 PF17380.2 KXZ49576.1 - 8.4 4.3 15.8 11 3.9 15.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SRAP PF02586.14 KXZ49577.1 - 3.2e-43 147.8 0.0 9.3e-43 146.3 0.0 1.6 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) RuvX PF03652.15 KXZ49578.1 - 3.5e-10 40.4 0.0 4.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Holliday junction resolvase Trimer_CC PF08954.11 KXZ49578.1 - 0.017 14.7 1.1 0.034 13.7 0.1 1.9 2 0 0 2 2 2 0 Trimerisation motif Serpulina_VSP PF05540.11 KXZ49578.1 - 0.2 10.6 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein End3 PF12761.7 KXZ49579.1 - 0.00021 21.6 1.5 0.00026 21.2 1.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 DUF4407 PF14362.6 KXZ49579.1 - 0.0014 18.1 4.4 0.0016 17.8 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 KXZ49579.1 - 0.0028 17.9 1.7 0.0056 17.0 1.7 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 UPF0242 PF06785.11 KXZ49579.1 - 0.0035 17.5 3.2 0.0045 17.1 3.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ALIX_LYPXL_bnd PF13949.6 KXZ49579.1 - 0.0039 16.5 4.2 0.005 16.2 4.2 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Uds1 PF15456.6 KXZ49579.1 - 0.0067 16.6 7.5 0.013 15.7 7.5 1.5 1 0 0 1 1 1 1 Up-regulated During Septation Spectrin PF00435.21 KXZ49579.1 - 0.0076 16.7 4.4 0.012 16.0 4.4 1.3 1 0 0 1 1 1 1 Spectrin repeat ZapB PF06005.12 KXZ49579.1 - 0.01 16.3 13.9 0.23 11.9 7.0 2.2 1 1 1 2 2 2 2 Cell division protein ZapB Leu_zip PF15294.6 KXZ49579.1 - 0.014 14.9 3.1 0.017 14.6 3.1 1.1 1 0 0 1 1 1 0 Leucine zipper OmpH PF03938.14 KXZ49579.1 - 0.015 15.6 4.1 0.021 15.1 4.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tektin PF03148.14 KXZ49579.1 - 0.017 13.9 3.1 0.017 13.9 3.1 1.5 1 1 0 1 1 1 0 Tektin family CENP-F_leu_zip PF10473.9 KXZ49579.1 - 0.025 14.6 10.2 0.052 13.6 10.2 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 KXZ49579.1 - 0.026 14.0 4.3 0.031 13.8 4.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-O PF09496.10 KXZ49579.1 - 0.028 14.4 0.8 0.035 14.1 0.8 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Fib_alpha PF08702.10 KXZ49579.1 - 0.036 14.3 1.3 0.049 13.8 1.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KXZ49579.1 - 0.038 11.5 4.3 0.046 11.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FapA PF03961.13 KXZ49579.1 - 0.038 12.6 1.5 0.047 12.3 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 KXZ49579.1 - 0.052 11.5 2.0 0.062 11.3 2.0 1.0 1 0 0 1 1 1 0 Prominin Muted PF14942.6 KXZ49579.1 - 0.062 13.6 3.8 0.082 13.2 3.8 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein AAA_13 PF13166.6 KXZ49579.1 - 0.063 11.9 3.2 0.078 11.6 3.2 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 KXZ49579.1 - 0.071 12.2 2.8 0.085 11.9 2.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 KXZ49579.1 - 0.081 13.1 3.1 6.1 7.1 0.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA FAM76 PF16046.5 KXZ49579.1 - 0.1 12.0 4.7 0.12 11.7 4.7 1.1 1 0 0 1 1 1 0 FAM76 protein V_ATPase_I PF01496.19 KXZ49579.1 - 0.11 10.5 2.5 0.12 10.3 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2730 PF10805.8 KXZ49579.1 - 0.11 12.6 2.2 0.22 11.6 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 KXZ49579.1 - 0.19 12.1 5.0 0.18 12.2 3.0 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KXZ49579.1 - 0.2 12.3 6.0 0.36 11.5 6.0 1.4 1 1 0 1 1 1 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 KXZ49579.1 - 0.21 11.1 8.0 0.26 10.8 8.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Allexi_40kDa PF05549.11 KXZ49579.1 - 0.32 10.5 2.5 0.45 10.0 2.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1664 PF07889.12 KXZ49579.1 - 0.35 10.9 3.9 0.54 10.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIVA PF05103.13 KXZ49579.1 - 0.35 10.9 9.1 0.59 10.2 9.1 1.3 1 0 0 1 1 1 0 DivIVA protein PIEZO PF15917.5 KXZ49579.1 - 0.36 10.3 2.6 0.55 9.7 2.6 1.3 1 0 0 1 1 1 0 Piezo Seryl_tRNA_N PF02403.22 KXZ49579.1 - 0.42 10.9 8.6 0.86 9.9 1.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 KXZ49579.1 - 0.52 9.6 8.9 0.96 8.8 8.9 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KXZ49579.1 - 0.54 11.2 10.8 0.17 12.8 5.0 1.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain ATG16 PF08614.11 KXZ49579.1 - 0.55 10.4 19.7 3.2 7.9 19.8 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GrpE PF01025.19 KXZ49579.1 - 0.68 9.6 9.9 7.7 6.2 9.9 2.0 1 1 0 1 1 1 0 GrpE ADIP PF11559.8 KXZ49579.1 - 0.7 10.0 10.5 1.6 8.8 7.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KXZ49579.1 - 0.71 10.4 15.9 0.53 10.8 6.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region BST2 PF16716.5 KXZ49579.1 - 0.91 10.2 9.0 0.15 12.6 3.4 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Rx_N PF18052.1 KXZ49579.1 - 0.93 9.8 4.7 0.33 11.2 1.5 1.7 1 1 1 2 2 2 0 Rx N-terminal domain DUF4404 PF14357.6 KXZ49579.1 - 1 10.1 7.5 3.9 8.2 5.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF4140 PF13600.6 KXZ49579.1 - 1.1 9.8 12.9 2.3 8.7 3.6 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 KXZ49579.1 - 1.1 8.0 10.6 2.4 7.0 10.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein GET2 PF08690.10 KXZ49579.1 - 1.2 8.7 8.1 1.6 8.3 8.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Uso1_p115_C PF04871.13 KXZ49579.1 - 1.4 9.3 13.9 1.4 9.3 13.2 1.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region LPP PF04728.13 KXZ49579.1 - 1.6 9.2 11.8 0.18 12.2 2.6 2.7 3 0 0 3 3 2 0 Lipoprotein leucine-zipper TSC22 PF01166.18 KXZ49579.1 - 2.1 8.7 7.9 2.2 8.7 3.9 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family 5_nucleotid PF05761.14 KXZ49579.1 - 2.3 7.0 4.2 2.8 6.7 4.2 1.0 1 0 0 1 1 1 0 5' nucleotidase family TMF_DNA_bd PF12329.8 KXZ49579.1 - 2.4 8.2 14.0 5 7.2 1.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 KXZ49579.1 - 2.6 7.8 8.1 10 5.9 8.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CENP-H PF05837.12 KXZ49579.1 - 3 8.3 11.4 9.2 6.7 11.4 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) SOBP PF15279.6 KXZ49579.1 - 3.8 8.0 11.2 4.4 7.8 11.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Spc24 PF08286.11 KXZ49579.1 - 5.2 7.4 8.8 14 5.9 8.8 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Csm1_N PF18504.1 KXZ49579.1 - 5.5 7.4 9.1 1 9.7 2.1 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain Rho_Binding PF08912.11 KXZ49579.1 - 7.3 7.5 11.1 3.7 8.4 4.0 2.2 1 1 1 2 2 2 0 Rho Binding SlyX PF04102.12 KXZ49579.1 - 7.8 7.2 8.7 2.8 8.6 2.4 2.6 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 KXZ49579.1 - 8.2 6.3 13.7 3.6 7.4 4.2 2.8 1 1 1 2 2 2 0 Septum formation initiator APH PF01636.23 KXZ49580.1 - 0.0013 18.8 0.4 0.11 12.4 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ49580.1 - 0.086 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 KXZ49581.1 - 4.7e-08 33.5 0.0 1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49581.1 - 1.9e-07 31.5 0.1 3.7e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49581.1 - 3.8e-06 26.8 0.0 0.16 12.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXZ49581.1 - 2.9e-05 24.2 0.6 0.00033 20.9 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49581.1 - 0.0001 22.6 0.7 0.18 12.3 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 KXZ49581.1 - 0.00014 21.6 3.3 0.00022 21.0 3.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ49581.1 - 0.0029 17.5 1.3 0.0049 16.7 1.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ49581.1 - 0.0038 17.5 4.1 0.0063 16.8 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KXZ49581.1 - 0.012 15.4 1.7 0.021 14.6 1.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KXZ49581.1 - 0.037 13.9 2.5 0.06 13.2 2.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KXZ49581.1 - 0.058 13.5 1.5 0.11 12.7 1.5 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KXZ49581.1 - 0.11 12.5 3.2 0.18 11.8 3.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXZ49581.1 - 0.39 10.8 1.8 0.77 9.8 1.8 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ49581.1 - 0.54 10.2 4.5 0.95 9.4 4.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MYND PF01753.18 KXZ49582.1 - 7e-07 29.2 10.4 2e-06 27.8 10.4 1.8 1 0 0 1 1 1 1 MYND finger T2SSF PF00482.23 KXZ49582.1 - 0.023 14.7 0.8 0.12 12.3 0.8 2.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F OTU PF02338.19 KXZ49583.1 - 2.1e-07 31.5 0.0 3.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UIM PF02809.20 KXZ49583.1 - 0.00034 20.3 0.7 0.00063 19.5 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin interaction motif HEM4 PF02602.15 KXZ49584.1 - 4.4e-42 144.0 0.0 5.5e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD UPF0180 PF03698.13 KXZ49584.1 - 0.086 13.0 0.0 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) tRNA-synt_2 PF00152.20 KXZ49584.1 - 0.12 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Glyco_trans_4_4 PF13579.6 KXZ49584.1 - 0.25 11.7 7.9 0.61 10.5 2.3 2.8 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain LicD PF04991.13 KXZ49586.1 - 0.11 12.6 6.3 0.16 12.1 6.3 1.2 1 0 0 1 1 1 0 LicD family Glyco_transf_21 PF13506.6 KXZ49587.1 - 4.2e-10 39.4 0.0 1.7e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXZ49587.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXZ49587.1 - 0.0001 22.3 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXZ49587.1 - 0.0003 20.8 0.1 0.00047 20.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF5568 PF17724.1 KXZ49589.1 - 0.12 12.2 1.4 0.15 11.9 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5568) Ank_2 PF12796.7 KXZ49591.1 - 0.00019 22.0 0.3 0.0025 18.4 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49591.1 - 0.013 16.1 4.7 3.2 8.4 0.0 4.1 3 2 1 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49592.1 - 2.7e-14 53.5 0.2 0.00021 21.8 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ49592.1 - 1.8e-11 43.2 3.9 0.14 12.8 0.0 8.8 9 0 0 9 9 9 2 Ankyrin repeat Ank_4 PF13637.6 KXZ49592.1 - 1.9e-11 44.3 7.1 1 10.0 0.1 7.4 5 3 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ49592.1 - 0.00023 21.4 11.3 1.3 9.5 0.0 6.8 5 3 2 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49592.1 - 0.0007 19.9 3.2 1.1 9.8 0.0 4.4 3 1 0 3 3 3 1 Ankyrin repeat SnoaL_2 PF12680.7 KXZ49592.1 - 0.87 10.3 8.1 3.3 8.4 0.2 3.9 2 2 1 3 3 3 0 SnoaL-like domain GARP PF16731.5 KXZ49593.1 - 0.00055 19.7 4.5 0.0007 19.3 4.5 1.2 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma Senescence PF06911.12 KXZ49593.1 - 0.0018 18.6 1.8 0.0021 18.4 1.8 1.2 1 0 0 1 1 1 1 Senescence-associated protein ApoLp-III PF07464.11 KXZ49593.1 - 0.0023 18.1 0.5 0.0026 17.9 0.5 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF4449 PF14613.6 KXZ49593.1 - 0.0044 17.2 2.4 0.0054 16.9 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) SOAR PF16533.5 KXZ49593.1 - 0.0059 16.5 0.5 0.26 11.3 0.0 2.1 1 1 1 2 2 2 1 STIM1 Orai1-activating region Apolipoprotein PF01442.18 KXZ49593.1 - 0.015 15.2 2.0 0.023 14.6 2.0 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.6 KXZ49593.1 - 0.077 13.3 1.3 0.077 13.3 1.3 1.9 2 0 0 2 2 2 0 MT0933-like antitoxin protein YtxH PF12732.7 KXZ49593.1 - 0.084 13.4 5.5 0.47 11.0 5.5 2.0 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 KXZ49593.1 - 0.28 11.8 6.7 0.11 13.1 4.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Grg1 PF11034.8 KXZ49593.1 - 0.29 11.4 5.9 0.85 9.9 4.8 2.1 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 EcKinase PF02958.20 KXZ49594.1 - 5.9e-05 22.5 0.0 0.00014 21.3 0.0 1.5 1 1 1 2 2 2 1 Ecdysteroid kinase APH PF01636.23 KXZ49594.1 - 0.00014 21.9 3.5 0.0002 21.4 3.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ49594.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_helicase PF00910.22 KXZ49595.1 - 0.02 15.2 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KXZ49595.1 - 0.096 13.0 0.0 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPP_enzyme_N PF02776.18 KXZ49597.1 - 3.1e-28 98.5 0.1 3.1e-28 98.5 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain GTP_EFTU PF00009.27 KXZ49597.1 - 4e-17 62.4 2.8 3.8e-06 26.6 0.0 3.1 2 1 1 3 3 3 3 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXZ49597.1 - 0.0054 17.1 0.3 0.02 15.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ49597.1 - 0.064 13.3 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3552 PF12072.8 KXZ49598.1 - 0.013 14.9 16.0 0.017 14.6 16.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CCDC-167 PF15188.6 KXZ49598.1 - 0.014 15.7 14.1 0.016 15.5 14.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3209 PF11483.8 KXZ49598.1 - 0.027 14.9 1.4 0.031 14.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Cob_adeno_trans PF01923.18 KXZ49598.1 - 0.036 14.2 1.2 0.037 14.2 1.2 1.0 1 0 0 1 1 1 0 Cobalamin adenosyltransferase PsbU PF06514.11 KXZ49598.1 - 0.047 13.7 0.5 0.061 13.3 0.5 1.3 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) FlxA PF14282.6 KXZ49598.1 - 0.1 12.6 5.3 0.15 12.1 5.3 1.3 1 0 0 1 1 1 0 FlxA-like protein Prefoldin_2 PF01920.20 KXZ49598.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit OmpH PF03938.14 KXZ49598.1 - 0.23 11.8 10.1 0.28 11.5 10.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 KXZ49598.1 - 0.98 7.9 10.0 1 7.9 10.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 KXZ49598.1 - 1.8 7.8 5.0 1.9 7.7 5.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein Tho2 PF11262.8 KXZ49598.1 - 2 7.5 6.9 2.5 7.2 6.9 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Snf7 PF03357.21 KXZ49598.1 - 4.3 6.9 15.6 2.7 7.6 0.6 2.0 1 1 1 2 2 2 0 Snf7 APG6_N PF17675.1 KXZ49598.1 - 6.5 7.3 19.2 3.9 8.0 1.8 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region UCR_Fe-S_N PF10399.9 KXZ49601.1 - 0.057 12.8 0.3 0.057 12.8 0.3 3.5 4 0 0 4 4 4 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ank_2 PF12796.7 KXZ49603.1 - 5.4e-06 26.9 1.6 0.017 15.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49603.1 - 0.00047 20.7 4.0 2.6 8.7 0.1 4.3 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49603.1 - 0.02 15.4 0.4 56 4.8 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat Ank_3 PF13606.6 KXZ49604.1 - 0.00024 21.3 0.2 2.9 8.7 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 KXZ49604.1 - 0.014 16.0 0.1 4.6 7.9 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49604.1 - 0.022 15.3 0.0 0.057 14.0 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 KXZ49605.1 - 1.1e-11 45.1 0.2 0.02 15.5 0.1 3.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49605.1 - 6.1e-08 33.1 12.7 0.95 10.1 0.0 6.0 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49605.1 - 5.9e-05 23.2 7.1 9.9 7.1 0.0 7.5 8 0 0 8 8 8 1 Ankyrin repeat Chorion_S16 PF05836.12 KXZ49605.1 - 0.27 11.5 3.1 0.34 11.2 0.1 2.8 3 0 0 3 3 3 0 Chorion protein S16 Ank_5 PF13857.6 KXZ49605.1 - 0.56 10.6 8.2 49 4.4 0.1 5.2 4 1 1 5 5 5 0 Ankyrin repeats (many copies) DUF2072 PF09845.9 KXZ49607.1 - 0.042 14.1 4.1 0.049 13.9 4.1 1.0 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF2807 PF10988.8 KXZ49607.1 - 1.6 8.5 5.2 2.3 8.0 5.2 1.3 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain HABP4_PAI-RBP1 PF04774.15 KXZ49607.1 - 2.3 9.1 10.3 3.1 8.7 10.3 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Presenilin PF01080.17 KXZ49607.1 - 5.2 5.7 13.7 5.2 5.7 13.7 1.0 1 0 0 1 1 1 0 Presenilin DUF3807 PF12720.7 KXZ49607.1 - 5.7 7.2 16.5 6.7 6.9 16.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Kei1 PF08552.11 KXZ49607.1 - 7.4 6.4 15.2 8.9 6.1 15.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Cdh1_DBD_1 PF18196.1 KXZ49607.1 - 7.5 6.9 11.1 12 6.2 11.1 1.4 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 GREB1 PF15782.5 KXZ49607.1 - 8.5 3.3 13.9 8.8 3.3 13.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IU_nuc_hydro PF01156.19 KXZ49608.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase Peptidase_M24_C PF16188.5 KXZ49610.1 - 1.9e-24 85.5 0.1 2.3e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Peptidase_M24 PF00557.24 KXZ49610.1 - 0.00029 20.6 0.1 0.00042 20.1 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 ThiF PF00899.21 KXZ49615.1 - 5.3e-13 48.9 0.0 1.5e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 ThiF family DUF883 PF05957.13 KXZ49615.1 - 0.011 16.3 1.1 0.028 15.0 1.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) EcsC PF12787.7 KXZ49615.1 - 1.5 8.5 5.3 3.6 7.2 0.3 2.3 2 0 0 2 2 2 0 EcsC protein family WW PF00397.26 KXZ49616.1 - 0.00013 22.0 0.2 0.00013 22.0 0.2 2.0 3 0 0 3 3 3 1 WW domain FoP_duplication PF13865.6 KXZ49616.1 - 6.5 7.4 9.0 9.9 6.8 9.0 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SnoaL_2 PF12680.7 KXZ49617.1 - 9.5e-08 32.6 0.3 1.2e-07 32.3 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KXZ49617.1 - 0.0024 18.1 0.0 0.0029 17.9 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXZ49617.1 - 0.0059 16.4 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase RR_TM4-6 PF06459.12 KXZ49619.1 - 0.66 9.8 11.7 1 9.1 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 KXZ49619.1 - 4.7 7.1 7.2 8.1 6.3 7.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 KXZ49619.1 - 5.6 5.6 7.1 8.5 5.0 7.1 1.2 1 0 0 1 1 1 0 Presenilin Ank_4 PF13637.6 KXZ49621.1 - 4.6e-10 39.8 7.0 0.24 12.0 0.3 6.3 4 3 1 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49621.1 - 5.1e-09 36.6 4.0 0.0026 18.3 0.2 5.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ49621.1 - 2.1e-05 24.5 1.1 66 4.6 0.1 6.2 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 KXZ49621.1 - 0.048 14.0 3.4 34 4.9 0.1 5.2 4 1 2 6 6 6 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49622.1 - 6e-06 26.8 0.0 0.014 16.0 0.0 1.8 1 1 1 2 2 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49622.1 - 0.0074 16.8 0.2 0.54 10.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49622.1 - 0.01 16.3 0.1 6 7.8 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KXZ49623.1 - 1.4e-11 44.8 0.2 6.9e-05 23.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49623.1 - 8.7e-09 35.7 6.2 0.0029 18.2 0.0 5.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49623.1 - 8.2e-06 25.8 3.1 1 10.1 0.0 6.6 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ49623.1 - 0.52 10.7 7.7 66 4.0 0.0 5.2 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ofd1_CTDD PF10637.9 KXZ49624.1 - 1.3e-59 201.6 0.0 5e-58 196.4 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KXZ49624.1 - 5.5e-23 81.5 0.0 1.4e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXZ49624.1 - 1.3e-12 48.4 0.1 4.9e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPT PF03151.16 KXZ49625.1 - 2.6e-18 66.4 4.2 2.6e-18 66.4 4.2 1.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ49625.1 - 0.3 11.3 25.5 0.16 12.2 8.1 2.8 3 1 0 3 3 3 0 EamA-like transporter family Chorein_N PF12624.7 KXZ49627.1 - 3.8e-15 56.0 0.0 6.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 CNDH2_C PF16858.5 KXZ49628.1 - 6.2e-36 124.8 0.0 9.1e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 KXZ49628.1 - 2e-34 118.2 0.0 3.8e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_M PF16869.5 KXZ49628.1 - 1.2 9.9 10.5 0.17 12.6 2.3 3.2 3 1 0 3 3 3 0 PF16858 Diphthamide_syn PF01866.17 KXZ49629.1 - 3.3e-108 361.7 0.0 4.2e-108 361.4 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein mTERF PF02536.14 KXZ49630.1 - 6.3e-26 91.0 0.0 2.7e-25 89.0 0.0 1.7 1 1 0 1 1 1 1 mTERF Integrase_Zn PF02022.19 KXZ49630.1 - 0.18 11.8 0.1 0.45 10.5 0.0 1.7 2 0 0 2 2 2 0 Integrase Zinc binding domain DUF737 PF05300.11 KXZ49631.1 - 0.085 13.2 2.9 0.1 12.9 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF2076 PF09849.9 KXZ49631.1 - 4.7 7.2 19.1 29 4.6 19.1 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) GTP_EFTU PF00009.27 KXZ49633.1 - 3.4e-25 88.7 0.0 5.7e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXZ49633.1 - 6.3e-09 36.1 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain zf-MYND PF01753.18 KXZ49633.1 - 0.00025 21.1 9.4 0.00065 19.7 9.4 1.7 1 0 0 1 1 1 1 MYND finger MMR_HSR1 PF01926.23 KXZ49633.1 - 0.0014 18.7 0.0 0.0039 17.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.22 KXZ49634.1 - 2.1e-15 56.3 0.0 3.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KXZ49634.1 - 1e-07 31.7 1.5 2e-07 30.7 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 KXZ49634.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif zf-CCHC_6 PF15288.6 KXZ49634.1 - 0.07 13.0 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-MYND PF01753.18 KXZ49637.1 - 4.4e-06 26.7 9.0 6.4e-06 26.1 9.0 1.3 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ49638.1 - 0.00013 22.0 9.0 0.00013 22.0 9.0 2.9 3 0 0 3 3 3 2 MYND finger zf-MYND PF01753.18 KXZ49640.1 - 1.6e-05 24.9 9.5 2.6e-05 24.2 9.5 1.3 1 0 0 1 1 1 1 MYND finger pKID PF02173.17 KXZ49641.1 - 0.017 14.6 1.1 0.033 13.7 1.1 1.4 1 0 0 1 1 1 0 pKID domain Daxx PF03344.15 KXZ49642.1 - 0.17 12.0 0.1 0.5 10.5 0.1 1.9 1 1 1 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain Dynamin_N PF00350.23 KXZ49643.1 - 8.3e-17 61.8 0.0 7.6e-16 58.6 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXZ49643.1 - 0.00038 20.5 0.0 0.0034 17.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KXZ49643.1 - 0.0086 15.8 1.1 0.011 15.5 0.1 1.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ49643.1 - 0.013 15.8 0.0 0.015 15.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KXZ49643.1 - 0.17 11.4 0.0 18 4.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_M PF01031.20 KXZ49644.1 - 8.8e-29 100.6 0.0 8.1e-14 51.5 0.0 2.5 3 0 0 3 3 3 2 Dynamin central region GED PF02212.18 KXZ49644.1 - 1e-05 25.6 0.2 7.8e-05 22.8 0.2 2.3 1 1 0 1 1 1 1 Dynamin GTPase effector domain LidA_Long_CC PF18641.1 KXZ49644.1 - 0.07 13.2 0.3 10 6.1 0.0 2.9 3 0 0 3 3 3 0 LidA long coiled-coil domain CBM_20 PF00686.19 KXZ49645.1 - 1.8e-21 75.8 0.1 3.2e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain TcpQ PF10671.9 KXZ49645.1 - 0.028 14.5 0.3 1.6 8.9 0.1 2.6 1 1 1 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q SAP PF02037.27 KXZ49646.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 SAP domain DUF2894 PF11445.8 KXZ49646.1 - 1.5 9.3 7.5 17 5.9 4.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) Peptidase_C1 PF00112.23 KXZ49648.1 - 1.9e-79 266.8 1.5 2.6e-79 266.4 1.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Granulin PF00396.18 KXZ49648.1 - 5.6e-11 42.6 24.5 5.6e-11 42.6 24.5 2.5 1 1 1 2 2 2 1 Granulin Inhibitor_I29 PF08246.12 KXZ49648.1 - 2.5e-08 34.2 1.1 4.2e-08 33.5 1.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KXZ49648.1 - 0.001 17.9 1.1 0.35 9.6 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family ubiquitin PF00240.23 KXZ49649.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family SPX PF03105.19 KXZ49649.1 - 0.062 13.2 1.1 0.11 12.3 1.1 1.3 1 0 0 1 1 1 0 SPX domain Rad60-SLD PF11976.8 KXZ49649.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Dynamitin PF04912.14 KXZ49649.1 - 0.23 10.8 0.8 0.9 8.8 0.0 2.2 2 1 1 3 3 3 0 Dynamitin GAS PF13851.6 KXZ49649.1 - 0.67 9.3 2.1 3.3 7.0 0.1 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding ABC_tran_CTD PF16326.5 KXZ49649.1 - 5.7 7.3 8.4 0.29 11.4 1.0 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain KELK PF15796.5 KXZ49650.1 - 0.00034 21.0 1.3 0.00034 21.0 1.3 2.3 1 1 0 2 2 2 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Baculo_PEP_C PF04513.12 KXZ49650.1 - 0.0013 18.8 1.4 0.0028 17.7 1.3 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 KXZ49650.1 - 0.0017 18.7 1.4 0.0096 16.2 0.5 2.3 1 1 1 2 2 1 1 Domain of unknown function (DUF5082) Spc7 PF08317.11 KXZ49650.1 - 0.0018 17.2 5.0 0.0021 17.0 5.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Prominin PF05478.11 KXZ49650.1 - 0.0019 16.3 2.3 0.002 16.2 2.3 1.1 1 0 0 1 1 1 1 Prominin CENP-H PF05837.12 KXZ49650.1 - 0.005 17.2 3.8 0.005 17.2 3.8 1.9 1 1 1 2 2 2 1 Centromere protein H (CENP-H) IFT57 PF10498.9 KXZ49650.1 - 0.0068 15.4 4.5 0.0082 15.2 4.5 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 FAM184 PF15665.5 KXZ49650.1 - 0.0079 16.0 6.5 0.01 15.7 6.5 1.2 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Golgin_A5 PF09787.9 KXZ49650.1 - 0.011 15.2 5.7 0.013 15.0 5.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 V-SNARE PF05008.15 KXZ49650.1 - 0.013 15.9 1.8 0.013 15.9 1.8 2.3 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF3584 PF12128.8 KXZ49650.1 - 0.014 12.9 6.4 0.015 12.9 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Apolipoprotein PF01442.18 KXZ49650.1 - 0.019 14.8 10.6 0.025 14.4 10.6 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NYD-SP28_assoc PF14775.6 KXZ49650.1 - 0.022 14.8 3.6 0.035 14.2 1.8 2.1 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF1640 PF07798.11 KXZ49650.1 - 0.023 14.7 4.4 0.25 11.4 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ECM11 PF15463.6 KXZ49650.1 - 0.024 15.2 1.9 0.033 14.8 1.9 1.3 1 0 0 1 1 1 0 Extracellular mutant protein 11 Fib_alpha PF08702.10 KXZ49650.1 - 0.027 14.7 1.4 0.039 14.1 1.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KXZ49650.1 - 0.029 13.7 7.2 0.032 13.6 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.18 KXZ49650.1 - 0.031 14.5 5.1 1.3 9.3 1.6 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.12 KXZ49650.1 - 0.045 13.8 2.9 0.12 12.5 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ax_dynein_light PF10211.9 KXZ49650.1 - 0.083 12.8 4.9 0.11 12.4 4.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Syntaxin-6_N PF09177.11 KXZ49650.1 - 0.091 13.3 3.1 0.18 12.4 3.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4618 PF15397.6 KXZ49650.1 - 0.1 12.0 6.5 0.093 12.1 4.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 KXZ49650.1 - 0.11 12.9 2.9 1.1 9.8 1.0 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXZ49650.1 - 0.12 12.8 0.7 14 6.2 0.0 3.2 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 KXZ49650.1 - 0.19 12.0 8.8 0.27 11.4 6.1 2.3 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 KXZ49650.1 - 0.2 12.0 8.9 0.97 9.8 8.9 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YabA PF06156.13 KXZ49650.1 - 0.21 12.2 4.6 2.2 9.0 4.6 2.1 1 1 0 1 1 1 0 Initiation control protein YabA HalX PF08663.10 KXZ49650.1 - 0.43 10.9 7.4 0.11 12.9 1.3 2.7 1 1 2 3 3 3 0 HalX domain bZIP_1 PF00170.21 KXZ49650.1 - 0.46 10.6 5.9 4.5 7.4 1.0 2.7 1 1 2 3 3 3 0 bZIP transcription factor Prefoldin_2 PF01920.20 KXZ49650.1 - 0.46 10.5 8.6 0.48 10.4 1.1 2.6 2 1 1 3 3 2 0 Prefoldin subunit ADIP PF11559.8 KXZ49650.1 - 0.47 10.5 9.2 0.61 10.2 3.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 KXZ49650.1 - 0.55 8.7 4.8 0.61 8.6 4.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 KXZ49650.1 - 0.58 10.6 8.6 0.33 11.4 1.3 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Ribosomal_L29 PF00831.23 KXZ49650.1 - 0.73 9.8 5.8 0.88 9.6 0.6 2.6 1 1 1 2 2 2 0 Ribosomal L29 protein FAM76 PF16046.5 KXZ49650.1 - 1.2 8.5 5.2 1 8.7 2.8 1.5 1 1 1 2 2 2 0 FAM76 protein bZIP_2 PF07716.15 KXZ49650.1 - 1.8 8.7 6.4 0.67 10.1 0.3 2.6 3 1 0 3 3 2 0 Basic region leucine zipper ABC1 PF03109.16 KXZ49651.1 - 1.7e-26 92.7 0.0 4.5e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXZ49651.1 - 2.2e-05 24.5 0.8 0.0002 21.4 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ49651.1 - 0.048 13.0 0.0 0.39 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein kinase domain CBM_20 PF00686.19 KXZ49652.1 - 1.2e-09 38.0 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain Spc7 PF08317.11 KXZ49652.1 - 0.0034 16.3 36.8 0.0091 14.9 12.9 2.5 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF5394 PF17372.2 KXZ49652.1 - 0.0044 16.6 3.9 0.009 15.6 3.9 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5394) Lipoprotein_7 PF01540.16 KXZ49652.1 - 0.034 13.4 7.0 0.05 12.9 7.0 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Baculo_PEP_C PF04513.12 KXZ49652.1 - 0.17 11.9 12.6 0.12 12.4 4.6 3.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KXZ49652.1 - 0.24 9.3 12.1 0.38 8.7 12.1 1.3 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 KXZ49652.1 - 0.28 11.2 13.5 3.4 7.7 5.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KXZ49652.1 - 0.44 9.6 26.5 0.52 9.3 5.9 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 KXZ49652.1 - 0.56 10.9 25.7 0.087 13.5 5.6 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4201 PF13870.6 KXZ49652.1 - 0.87 9.3 20.6 0.1 12.3 3.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) AAA_13 PF13166.6 KXZ49652.1 - 1.1 7.8 24.9 0.035 12.8 10.7 1.8 1 1 1 2 2 2 0 AAA domain Syntaxin PF00804.25 KXZ49652.1 - 1.1 8.8 23.1 0.038 13.6 10.2 2.4 1 1 1 2 2 2 0 Syntaxin ATG16 PF08614.11 KXZ49652.1 - 1.4 9.1 44.5 2.8 8.1 16.3 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXZ49652.1 - 2.1 7.2 33.3 0.47 9.3 19.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FliD_C PF07195.12 KXZ49652.1 - 2.6 7.4 12.5 4.4 6.6 0.0 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Filament PF00038.21 KXZ49652.1 - 3.1 7.3 33.1 2.1 7.8 15.8 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF1759 PF03564.15 KXZ49652.1 - 3.3 7.6 5.5 0.56 10.1 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Peptidase_S46 PF10459.9 KXZ49652.1 - 6.4 5.3 18.9 9 4.8 18.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Fib_alpha PF08702.10 KXZ49652.1 - 6.6 6.9 18.5 4 7.6 10.8 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF501 PF04417.12 KXZ49652.1 - 8.3 6.2 16.2 0.031 14.1 2.7 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF501) TPR_MLP1_2 PF07926.12 KXZ49652.1 - 8.7 6.4 49.4 4.5 7.3 18.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.25 KXZ49653.1 - 1.7e-33 116.2 0.0 3.5e-30 105.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49653.1 - 2.7e-26 92.4 0.0 8.7e-23 80.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ49653.1 - 0.0055 16.6 0.0 0.0088 16.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ49653.1 - 0.012 14.4 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PglD_N PF17836.1 KXZ49653.1 - 0.13 12.9 0.1 0.23 12.1 0.1 1.3 1 0 0 1 1 1 0 PglD N-terminal domain Pkinase PF00069.25 KXZ49654.1 - 1.2e-43 149.4 0.0 1.8e-40 139.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49654.1 - 4.1e-42 144.3 0.0 1.1e-38 133.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ49654.1 - 0.0043 17.0 0.4 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ49654.1 - 0.046 12.5 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PglD_N PF17836.1 KXZ49654.1 - 0.094 13.4 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 PglD N-terminal domain Pkinase PF00069.25 KXZ49655.1 - 1e-18 67.7 0.0 1.1e-15 57.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49655.1 - 5.9e-17 61.8 0.0 1.7e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PglD_N PF17836.1 KXZ49655.1 - 0.2 12.3 0.0 0.33 11.6 0.0 1.3 1 0 0 1 1 1 0 PglD N-terminal domain EcKinase PF02958.20 KXZ49656.1 - 0.00014 21.3 0.0 0.00044 19.7 0.0 1.6 1 1 1 2 2 2 1 Ecdysteroid kinase APH PF01636.23 KXZ49656.1 - 0.0079 16.1 9.0 0.051 13.5 8.2 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family MscS_porin PF12795.7 KXZ49658.1 - 0.024 14.2 3.3 0.029 13.9 3.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Methyltrans_SAM PF10672.9 KXZ49659.1 - 9.8e-25 87.3 0.0 1.3e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 KXZ49659.1 - 2.3e-07 30.6 0.0 4.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PUA_3 PF17785.1 KXZ49659.1 - 5.5e-05 22.9 0.1 0.00034 20.4 0.0 2.4 3 0 0 3 3 3 1 PUA-like domain AAA_25 PF13481.6 KXZ49659.1 - 0.00034 20.3 0.2 0.00079 19.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Methyltransf_31 PF13847.6 KXZ49659.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KXZ49659.1 - 0.0019 18.0 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KXZ49659.1 - 0.0055 16.3 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXZ49659.1 - 0.097 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3363 PF11843.8 KXZ49660.1 - 0.063 12.2 0.1 0.085 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) BTB PF00651.31 KXZ49661.1 - 2e-15 57.0 0.0 1.5e-14 54.1 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BTB PF00651.31 KXZ49662.1 - 2.8e-15 56.5 0.0 5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ49663.1 - 1e-11 45.1 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Reg_prop PF07494.11 KXZ49663.1 - 0.13 12.6 0.1 3.2 8.3 0.1 2.7 2 0 0 2 2 2 0 Two component regulator propeller SOUL PF04832.12 KXZ49665.1 - 3.9e-38 131.3 0.0 5.6e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein Acetyltransf_1 PF00583.25 KXZ49665.1 - 1e-08 35.4 0.0 2.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXZ49665.1 - 1.8e-08 34.2 0.0 4.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KXZ49665.1 - 2.7e-06 27.3 0.0 4.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ49665.1 - 3.1e-06 27.5 0.0 8.8e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXZ49665.1 - 0.01 15.9 0.0 0.046 13.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXZ49665.1 - 0.11 13.1 0.0 0.42 11.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXZ49665.1 - 0.27 10.7 0.0 0.42 10.0 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Abhydrolase_1 PF00561.20 KXZ49666.1 - 3.5e-17 62.9 0.0 8e-15 55.2 0.0 3.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ49666.1 - 9.2e-15 55.8 27.3 9.2e-15 55.8 27.3 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ49666.1 - 1.6e-10 40.7 0.2 7.3e-08 32.0 0.0 3.2 4 0 0 4 4 4 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KXZ49666.1 - 2.8e-06 27.3 0.0 0.0003 20.7 0.1 2.6 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.14 KXZ49666.1 - 0.0002 20.2 0.0 0.003 16.3 0.0 2.0 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.13 KXZ49666.1 - 0.0019 18.1 0.9 0.0019 18.1 0.9 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KXZ49666.1 - 0.004 16.8 0.1 0.013 15.1 0.1 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 KXZ49666.1 - 0.0063 16.3 0.0 0.087 12.6 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KXZ49666.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 KXZ49666.1 - 0.013 15.0 0.0 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KXZ49666.1 - 0.021 14.9 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_4 PF08386.10 KXZ49666.1 - 0.037 14.1 0.3 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein Chlorophyllase2 PF12740.7 KXZ49666.1 - 0.2 10.6 0.1 0.48 9.3 0.1 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme BTB PF00651.31 KXZ49667.1 - 0.00024 21.3 0.0 0.00051 20.2 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ49668.1 - 5.9e-14 52.3 0.0 9.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DEC-1_N PF04625.13 KXZ49668.1 - 0.85 8.6 3.4 1.2 8.1 3.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region BTB PF00651.31 KXZ49669.1 - 9.5e-16 58.0 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 KXZ49670.1 - 1.6e-18 67.1 0.3 4.7e-08 33.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49670.1 - 1e-15 57.9 0.0 4.2e-13 49.5 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49670.1 - 1.1e-13 50.0 0.1 3.8e-05 23.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXZ49670.1 - 8.8e-13 48.2 0.4 6.6e-09 35.9 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49670.1 - 6.5e-11 42.2 0.0 0.00038 20.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat NAD_binding_8 PF13450.6 KXZ49671.1 - 7.2e-15 55.0 1.5 2.1e-14 53.5 1.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXZ49671.1 - 8e-13 48.5 1.5 8.1e-07 28.7 0.0 2.6 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXZ49671.1 - 1e-09 38.0 0.9 6.8e-05 22.1 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXZ49671.1 - 5.5e-09 36.1 8.4 2e-07 30.9 8.4 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXZ49671.1 - 3.2e-05 23.3 0.1 0.00012 21.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KXZ49671.1 - 9e-05 21.8 0.8 0.00019 20.8 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ49671.1 - 0.0005 18.9 0.0 0.028 13.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXZ49671.1 - 0.0016 17.9 0.1 0.049 13.0 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXZ49671.1 - 0.0016 18.9 0.2 0.017 15.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXZ49671.1 - 0.0042 16.4 0.1 0.0065 15.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXZ49671.1 - 0.21 10.6 0.4 0.36 9.9 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A CDC24_OB1 PF17246.2 KXZ49672.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 FAST_1 PF06743.15 KXZ49673.1 - 0.21 11.6 0.0 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Ribonuc_P_40 PF08584.11 KXZ49674.1 - 6.1e-34 117.6 0.0 2.7e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit ADH_zinc_N_2 PF13602.6 KXZ49674.1 - 0.012 16.7 0.0 0.04 15.0 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase BTB PF00651.31 KXZ49675.1 - 7.1e-15 55.2 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Interfer-bind PF09294.10 KXZ49676.1 - 0.16 12.3 0.0 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Guanylate_cyc PF00211.20 KXZ49678.1 - 1.6e-50 171.3 0.0 2e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KXZ49678.1 - 6.4e-28 97.7 0.0 8.8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Heme NO binding associated SIP1 PF04938.12 KXZ49679.1 - 1.3e-10 41.4 0.0 2.7e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SelK_SelG PF10961.8 KXZ49679.1 - 0.3 11.7 6.2 0.59 10.8 6.2 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG GATase PF00117.28 KXZ49681.1 - 7.6e-19 68.2 0.0 8.8e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SUKH-3 PF14433.6 KXZ49681.1 - 0.11 12.9 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 SUKH-3 immunity protein CTP_synth_N PF06418.14 KXZ49682.1 - 1.4e-104 349.1 0.0 2e-104 348.6 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KXZ49682.1 - 1.5e-28 99.9 0.0 2.3e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I BPL_LplA_LipB PF03099.19 KXZ49683.1 - 5.1e-20 71.7 0.0 7.9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Thioredoxin_8 PF13905.6 KXZ49685.1 - 1.3e-14 54.3 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Pkinase_Tyr PF07714.17 KXZ49686.1 - 7.9e-56 189.2 0.0 1e-55 188.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49686.1 - 1.5e-45 155.6 0.0 2.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TFIID_30kDa PF03540.13 KXZ49686.1 - 0.15 12.0 0.2 0.99 9.4 0.0 2.5 3 0 0 3 3 3 0 Transcription initiation factor TFIID 23-30kDa subunit Complex1_49kDa PF00346.19 KXZ49687.1 - 5.9e-123 409.3 0.0 7.1e-123 409.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KXZ49687.1 - 0.15 10.9 0.0 0.47 9.3 0.0 1.7 1 1 1 2 2 2 0 Nickel-dependent hydrogenase CBS PF00571.28 KXZ49688.1 - 1.2e-28 99.3 3.9 5.1e-14 52.4 0.2 2.2 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 KXZ49688.1 - 0.0025 17.9 0.3 0.48 10.6 0.0 2.4 2 0 0 2 2 2 2 PRC-barrel domain sCache_3_2 PF17203.4 KXZ49688.1 - 0.011 15.9 0.1 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Single cache domain 3 ProRS-C_1 PF09180.11 KXZ49690.1 - 1.2e-17 63.9 0.0 2.6e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KXZ49690.1 - 9e-17 61.0 0.0 1.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXZ49690.1 - 0.039 13.9 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) HlyD_D23 PF16576.5 KXZ49692.1 - 0.0034 16.6 0.2 0.075 12.2 0.1 2.2 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Ank_2 PF12796.7 KXZ49693.1 - 2.9e-09 37.4 0.0 0.0027 18.3 0.0 4.3 2 2 4 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49693.1 - 6.6e-09 36.1 5.0 0.065 13.8 0.0 6.6 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49693.1 - 8.8e-06 25.7 0.1 1.1e+02 3.9 0.0 7.7 8 0 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ49693.1 - 0.012 15.9 2.0 14 6.2 0.0 4.3 4 1 1 5 5 5 0 Ankyrin repeats (many copies) SAM_1 PF00536.30 KXZ49693.1 - 0.11 13.0 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Vac14_Fig4_bd PF11916.8 KXZ49694.1 - 0.19 11.3 0.1 0.55 9.9 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding DUF4880 PF16220.5 KXZ49695.1 - 0.033 14.1 1.3 0.033 14.1 1.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4880) Thi4 PF01946.17 KXZ49695.1 - 0.091 12.0 0.2 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Band_7_C PF16200.5 KXZ49696.1 - 0.00049 20.1 0.3 0.0024 17.9 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of band_7 DUF4880 PF16220.5 KXZ49696.1 - 0.014 15.3 9.6 0.071 13.0 1.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) Thi4 PF01946.17 KXZ49696.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family PseudoU_synth_1 PF01416.20 KXZ49697.1 - 3.8e-22 78.8 0.0 5.6e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Rv2175c_C PF18367.1 KXZ49699.1 - 0.038 14.1 0.5 0.13 12.4 0.0 2.1 3 0 0 3 3 3 0 Rv2175c C-terminal domain of unknown function cobW PF02492.19 KXZ49700.1 - 7.1e-42 143.0 0.2 1.2e-41 142.2 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ49700.1 - 3.5e-22 78.2 0.0 8.9e-22 76.8 0.0 1.8 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_33 PF13671.6 KXZ49700.1 - 0.002 18.3 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Macoilin PF09726.9 KXZ49700.1 - 0.016 13.8 6.8 0.02 13.5 6.8 1.2 1 0 0 1 1 1 0 Macoilin family RsgA_GTPase PF03193.16 KXZ49700.1 - 0.023 14.6 0.1 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SoxG PF04268.12 KXZ49700.1 - 0.038 14.1 0.2 0.067 13.3 0.2 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family AAA_16 PF13191.6 KXZ49700.1 - 0.055 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Spt20 PF12090.8 KXZ49701.1 - 0.033 13.8 5.3 0.046 13.3 5.3 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 KXZ49701.1 - 0.12 11.3 1.3 0.15 11.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SnoaL_2 PF12680.7 KXZ49704.1 - 0.0028 18.3 0.2 0.0068 17.0 0.2 1.7 1 0 0 1 1 1 1 SnoaL-like domain WD40 PF00400.32 KXZ49705.1 - 7.9e-25 86.6 17.6 3.2e-06 27.8 0.1 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ49705.1 - 2.9e-14 53.1 3.9 0.00023 21.4 0.2 4.7 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S24 PF00717.23 KXZ49705.1 - 1.8e-10 40.6 0.3 3.5e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase S24-like eIF2A PF08662.11 KXZ49705.1 - 7.4e-07 29.2 0.0 1 9.2 0.1 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KXZ49705.1 - 0.046 13.0 0.5 1.2 8.4 0.0 2.6 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KXZ49705.1 - 0.085 11.8 0.0 0.72 8.7 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXZ49705.1 - 0.16 10.5 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Bacteriocin_II PF01721.18 KXZ49705.1 - 2.8 8.1 4.8 26 5.0 0.0 2.8 3 0 0 3 3 3 0 Class II bacteriocin UDPGT PF00201.18 KXZ49706.1 - 1.8e-25 89.7 0.0 4.2e-19 68.7 0.0 3.3 4 0 0 4 4 4 3 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXZ49706.1 - 0.0025 17.8 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 KXZ49706.1 - 0.02 14.2 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 1 Glyco_transf_5 PF08323.11 KXZ49706.1 - 0.074 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Ammonium_transp PF00909.21 KXZ49707.1 - 7.6e-108 360.7 15.8 9.1e-108 360.5 15.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.8 KXZ49707.1 - 0.053 13.6 2.1 0.3 11.1 2.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) F-box-like PF12937.7 KXZ49708.1 - 0.013 15.4 0.3 0.072 13.0 0.2 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KXZ49708.1 - 0.023 14.6 3.8 0.068 13.1 0.3 2.6 2 0 0 2 2 2 0 F-box domain SDA1 PF05285.12 KXZ49708.1 - 0.37 10.2 5.0 0.51 9.7 5.0 1.2 1 0 0 1 1 1 0 SDA1 SLC35F PF06027.12 KXZ49709.1 - 1.1e-51 176.2 0.1 1.3e-51 175.9 0.1 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KXZ49709.1 - 3.9e-08 32.6 0.0 4.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KXZ49709.1 - 9.7e-08 32.3 6.6 2.9e-06 27.5 4.9 2.2 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 KXZ49709.1 - 1.7e-05 24.2 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 UAA transporter family Mg_trans_NIPA PF05653.14 KXZ49709.1 - 0.61 9.1 3.6 0.21 10.6 0.9 1.5 2 0 0 2 2 2 0 Magnesium transporter NIPA Ribosomal_S9 PF00380.19 KXZ49710.1 - 8.3e-35 119.9 0.2 1.6e-34 119.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BTB PF00651.31 KXZ49711.1 - 1.4e-06 28.5 0.0 1.4e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ49713.1 - 3.1e-05 24.2 0.0 4.8e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Ank_3 PF13606.6 KXZ49714.1 - 3.3e-14 51.6 0.0 6.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXZ49714.1 - 5.7e-13 48.8 0.0 2.7e-07 30.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49714.1 - 2.6e-12 47.2 0.0 4.6e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ49714.1 - 6.4e-11 42.2 0.0 0.00015 22.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXZ49714.1 - 1.9e-10 41.1 0.0 2.5e-05 24.7 0.0 2.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) ABC2_membrane PF01061.24 KXZ49715.1 - 6.2e-26 91.1 18.4 8.3e-26 90.7 18.4 1.1 1 0 0 1 1 1 1 ABC-2 type transporter Ank_2 PF12796.7 KXZ49716.1 - 3.2e-42 143.0 10.3 7.7e-14 52.1 0.0 5.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49716.1 - 5e-33 113.0 3.8 6.6e-08 33.0 0.0 6.2 3 3 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49716.1 - 8e-28 93.4 7.9 0.0014 18.9 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KXZ49716.1 - 1.7e-27 94.6 16.6 7.7e-06 26.1 0.1 9.1 8 2 1 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KXZ49716.1 - 3.5e-24 84.5 17.1 9.3e-09 35.4 0.3 7.7 2 2 6 8 8 8 6 Ankyrin repeats (many copies) PTS_IIA PF02255.16 KXZ49716.1 - 2.2 8.4 5.0 4.4 7.4 0.4 3.2 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit HMA PF00403.26 KXZ49717.1 - 2.3e-32 111.2 0.0 1.5e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KXZ49717.1 - 2.4e-22 79.3 2.0 7.4e-22 77.7 2.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase FeS_assembly_P PF01883.19 KXZ49717.1 - 0.57 10.4 3.0 26 5.1 0.2 3.4 3 0 0 3 3 3 0 Iron-sulfur cluster assembly protein UBX PF00789.20 KXZ49719.1 - 2.6e-13 50.0 0.0 4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 UBX domain Tmemb_14 PF03647.13 KXZ49720.1 - 0.15 12.8 6.6 0.2 12.4 6.6 1.2 1 0 0 1 1 1 0 Transmembrane proteins 14C Prefoldin_2 PF01920.20 KXZ49721.1 - 1e-13 51.1 1.7 1e-13 51.1 1.7 4.3 2 2 1 3 3 3 1 Prefoldin subunit ATG16 PF08614.11 KXZ49721.1 - 5e-05 23.6 26.5 5e-05 23.6 26.5 2.7 1 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KXZ49721.1 - 0.00068 18.6 18.5 0.00068 18.6 18.5 2.6 2 1 1 3 3 3 2 Spc7 kinetochore protein AIP3 PF03915.13 KXZ49721.1 - 0.00098 18.3 14.6 0.0035 16.5 14.3 1.9 1 1 0 1 1 1 1 Actin interacting protein 3 Tropomyosin PF00261.20 KXZ49721.1 - 0.0025 17.2 26.4 0.0047 16.3 26.4 1.4 1 0 0 1 1 1 1 Tropomyosin Vps54_N PF10475.9 KXZ49721.1 - 0.0072 15.6 8.8 0.05 12.9 4.9 2.4 1 1 1 2 2 2 2 Vacuolar-sorting protein 54, of GARP complex LCIB_C_CA PF18599.1 KXZ49721.1 - 0.22 10.8 5.7 0.33 10.2 5.2 1.6 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Mod_r PF07200.13 KXZ49721.1 - 0.27 11.3 29.2 0.14 12.3 13.1 3.5 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein LMBR1 PF04791.16 KXZ49721.1 - 0.3 10.0 3.3 0.39 9.6 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Tropomyosin_1 PF12718.7 KXZ49721.1 - 0.31 11.2 27.7 13 6.0 17.7 3.2 1 1 1 2 2 2 0 Tropomyosin like FlaC_arch PF05377.11 KXZ49721.1 - 0.58 10.6 14.1 15 6.1 0.4 4.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF1318 PF07027.12 KXZ49721.1 - 0.62 10.5 6.2 0.73 10.3 3.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1318) TPR_MLP1_2 PF07926.12 KXZ49721.1 - 0.79 9.8 39.9 0.23 11.5 0.5 4.1 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 KXZ49721.1 - 1 9.3 20.0 0.73 9.9 2.3 3.3 1 1 2 3 3 3 0 Laminin Domain II DUF4795 PF16043.5 KXZ49721.1 - 1.1 8.9 21.9 3 7.4 21.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) APG17 PF04108.12 KXZ49721.1 - 1.8 7.6 20.0 2.4 7.2 6.2 2.4 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF3782 PF12644.7 KXZ49721.1 - 2.1 8.6 5.6 2.3 8.4 0.2 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3782) MAD PF05557.13 KXZ49721.1 - 2.2 6.6 30.6 0.64 8.3 19.4 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4407 PF14362.6 KXZ49721.1 - 2.3 7.5 28.6 0.97 8.7 12.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Leu_zip PF15294.6 KXZ49721.1 - 2.9 7.3 19.6 1.2 8.6 12.7 2.6 1 1 2 3 3 3 0 Leucine zipper Sipho_Gp157 PF05565.11 KXZ49721.1 - 3.2 7.7 15.7 1.2 9.2 1.0 2.7 2 1 1 3 3 3 0 Siphovirus Gp157 AAA_13 PF13166.6 KXZ49721.1 - 4.9 5.7 17.8 2.2 6.8 1.4 2.2 1 1 1 2 2 2 0 AAA domain MutS_III PF05192.18 KXZ49721.1 - 5 7.3 11.2 9.6 6.4 11.2 1.5 1 0 0 1 1 1 0 MutS domain III Syntaxin-6_N PF09177.11 KXZ49721.1 - 5.8 7.5 14.3 1.2e+03 0.1 14.3 3.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal OEP PF02321.18 KXZ49721.1 - 6 6.6 30.2 0.042 13.7 13.5 3.6 2 1 2 4 4 4 0 Outer membrane efflux protein COG2 PF06148.11 KXZ49721.1 - 6.1 6.9 19.3 6.1 6.9 0.7 3.9 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 PIN_8 PF18476.1 KXZ49721.1 - 7 6.4 13.4 0.81 9.5 5.3 2.6 1 1 2 3 3 3 0 PIN like domain REF PF05755.12 KXZ49723.1 - 4.5e-07 29.9 2.6 8e-07 29.1 2.6 1.4 1 1 0 1 1 1 1 Rubber elongation factor protein (REF) Alpha_kinase PF02816.18 KXZ49724.1 - 1e-32 113.7 0.0 1.6e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KXZ49724.1 - 1.4e-05 25.7 0.0 3.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Atg29_N PF18388.1 KXZ49724.1 - 0.056 13.3 0.4 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Atg29 N-terminal domain Ank_4 PF13637.6 KXZ49728.1 - 0.00012 22.5 1.6 9.5 6.9 0.1 5.3 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49728.1 - 0.004 17.7 0.8 13 6.5 0.2 4.0 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ49728.1 - 0.017 15.6 2.8 21 6.1 0.0 5.2 6 0 0 6 6 6 0 Ankyrin repeat LRR_4 PF12799.7 KXZ49729.1 - 3 8.4 5.4 2.5e+02 2.3 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ49729.1 - 3.2 7.6 8.1 5.5 6.8 0.3 4.1 5 0 0 5 5 5 0 Leucine rich repeat Ank_4 PF13637.6 KXZ49731.1 - 0.00025 21.5 0.0 0.5 11.0 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) TIM21 PF08294.11 KXZ49733.1 - 6.8e-19 68.2 0.0 1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KXZ49733.1 - 0.069 12.9 0.0 0.21 11.3 0.0 1.9 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 DUF4244 PF14029.6 KXZ49733.1 - 0.15 11.5 1.5 0.26 10.7 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) ECSCR PF15820.5 KXZ49733.1 - 0.16 11.8 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SNARE PF05739.19 KXZ49734.1 - 8.7e-07 28.8 0.1 1.2e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.13 KXZ49734.1 - 0.032 14.1 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Sec20 RNA_pol_Rpb5_C PF01191.19 KXZ49735.1 - 3.4e-34 116.5 0.1 6.2e-34 115.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KXZ49735.1 - 8.4e-24 84.0 0.1 1.4e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KXZ49735.1 - 0.00019 21.4 0.0 0.00051 20.1 0.0 1.7 2 0 0 2 2 2 1 Restriction endonuclease LpxI_N PF17930.1 KXZ49735.1 - 0.067 13.1 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 LpxI N-terminal domain SH2_2 PF14633.6 KXZ49736.1 - 9.5e-19 67.7 0.0 9.5e-19 67.7 0.0 2.2 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 KXZ49736.1 - 6.8e-14 52.1 0.0 1.3e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 KXZ49736.1 - 7.8e-12 45.6 35.3 7.8e-12 45.6 35.3 4.4 3 1 0 3 3 3 1 Acidic N-terminal SPT6 YqgF PF14639.6 KXZ49736.1 - 1.8e-07 31.1 0.0 6.5e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_9 PF17674.1 KXZ49736.1 - 1.1e-05 26.3 0.0 6.5e-05 23.8 0.0 2.5 1 0 0 1 1 1 1 HHH domain HTH_44 PF14641.6 KXZ49736.1 - 0.013 15.9 0.1 0.11 12.9 0.1 2.3 1 1 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 Hydrolase_3 PF08282.12 KXZ49737.1 - 1.5e-25 90.4 0.0 1.6e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXZ49737.1 - 6.2e-10 39.0 0.0 7.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KXZ49737.1 - 0.0052 17.1 0.0 0.007 16.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Oxidored_molyb PF00174.19 KXZ49738.1 - 3.6e-56 189.4 0.0 6.1e-56 188.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXZ49738.1 - 8.6e-52 174.8 0.8 1.7e-51 173.9 0.8 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 KXZ49738.1 - 3.1e-34 117.3 0.0 9.5e-34 115.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXZ49738.1 - 1.5e-30 106.1 0.0 3.8e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXZ49738.1 - 2.3e-24 85.3 0.0 5.1e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXZ49738.1 - 0.00035 20.7 0.0 0.0015 18.7 0.0 2.0 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF3707 PF12499.8 KXZ49739.1 - 2.3e-33 115.8 26.6 3.1e-19 69.9 11.1 3.3 3 0 0 3 3 3 3 Pherophorin Cadherin-like PF12733.7 KXZ49739.1 - 0.11 13.0 0.1 0.29 11.7 0.1 1.7 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Rad50_zn_hook PF04423.14 KXZ49739.1 - 5.2 7.0 5.8 0.7 9.8 0.7 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Pkinase PF00069.25 KXZ49740.1 - 3.2e-23 82.4 0.0 2.2e-14 53.5 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49740.1 - 4.3e-18 65.5 0.0 3.4e-13 49.5 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49741.1 - 1e-19 71.0 0.0 1.3e-17 64.0 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49741.1 - 2.7e-10 40.0 0.0 8.5e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ49741.1 - 6.7e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ49741.1 - 0.00061 18.7 0.1 0.00088 18.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ49741.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXZ49741.1 - 0.0025 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXZ49741.1 - 0.0041 16.7 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KXZ49741.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KXZ49741.1 - 0.094 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3437 PF11919.8 KXZ49742.1 - 0.017 15.1 0.3 4.9 7.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Tetraspanin PF00335.20 KXZ49743.1 - 3.6e-05 23.6 7.1 0.00047 19.9 7.1 2.0 1 1 0 1 1 1 1 Tetraspanin family Mod_r PF07200.13 KXZ49743.1 - 0.0092 16.1 0.2 0.014 15.5 0.2 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF4728 PF15860.5 KXZ49743.1 - 0.04 14.6 1.1 1.5 9.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) TMEM107 PF14995.6 KXZ49743.1 - 0.075 13.5 2.6 0.84 10.1 0.1 2.3 1 1 1 2 2 2 0 Transmembrane protein DUF3810 PF12725.7 KXZ49743.1 - 0.11 11.9 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF883 PF05957.13 KXZ49743.1 - 0.15 12.7 0.2 0.34 11.5 0.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ArAE_2_N PF10337.9 KXZ49744.1 - 0.83 8.6 4.7 1.7 7.6 4.7 1.5 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal NAPRTase_C PF17956.1 KXZ49744.1 - 4.3 7.8 4.9 3.5 8.1 0.5 2.7 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain HALZ PF02183.18 KXZ49744.1 - 4.5 7.6 10.1 54 4.1 0.1 5.0 5 0 0 5 5 5 0 Homeobox associated leucine zipper MgtE PF01769.16 KXZ49746.1 - 1.7e-19 70.4 5.8 2.6e-19 69.8 5.8 1.3 1 0 0 1 1 1 1 Divalent cation transporter Pkinase PF00069.25 KXZ49747.1 - 1.2e-41 142.8 0.0 2.5e-38 131.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49747.1 - 3.8e-37 128.0 0.0 2e-34 119.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49747.1 - 0.0091 14.8 0.3 0.022 13.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXZ49747.1 - 0.1 12.5 7.1 0.026 14.4 0.6 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Roughex PF06020.11 KXZ49747.1 - 0.6 9.2 7.6 1.2 8.1 7.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein zf-MYND PF01753.18 KXZ49748.1 - 0.2 11.8 9.5 0.4 10.8 9.5 1.5 1 0 0 1 1 1 0 MYND finger Na_Ca_ex PF01699.24 KXZ49749.1 - 2.6e-33 115.1 35.4 4.5e-18 65.7 14.1 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Peptidase_C13 PF01650.18 KXZ49751.1 - 1.4e-53 182.0 0.0 1.6e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family RelB PF04221.12 KXZ49751.1 - 0.073 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 RelB antitoxin Hamartin PF04388.12 KXZ49752.1 - 6.8 5.2 4.8 7.8 5.0 4.8 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4878 PF12870.7 KXZ49752.1 - 7.4 6.9 9.9 1.9 8.8 2.7 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4878) PqqD PF05402.12 KXZ49753.1 - 1.7 9.0 3.5 12 6.3 0.7 3.0 2 1 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Linker_histone PF00538.19 KXZ49753.1 - 4 7.9 7.8 3.5 8.1 0.1 3.2 2 1 0 3 3 3 0 linker histone H1 and H5 family AMPK1_CBM PF16561.5 KXZ49754.1 - 7.3e-28 96.6 0.0 1.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBS PF00571.28 KXZ49754.1 - 3.8e-17 62.5 0.3 1.9e-06 28.2 0.3 4.2 4 0 0 4 4 4 3 CBS domain CBM_48 PF02922.18 KXZ49754.1 - 2.5e-05 24.5 0.0 4.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) TFIIA PF03153.13 KXZ49754.1 - 0.049 13.6 6.6 0.078 13.0 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAF4 PF05236.14 KXZ49754.1 - 3.2 7.4 6.6 12 5.5 2.4 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Fer4_24 PF18109.1 KXZ49755.1 - 0.049 13.9 0.2 0.42 10.9 0.0 2.4 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain AAA_6 PF12774.7 KXZ49756.1 - 2.9e-158 526.0 0.0 5.5e-158 525.1 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KXZ49756.1 - 3e-138 461.9 3.3 3e-138 461.9 3.3 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KXZ49756.1 - 1.6e-125 419.4 5.3 1.6e-125 419.4 5.3 5.3 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXZ49756.1 - 4.9e-103 344.0 0.0 1.3e-100 336.0 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXZ49756.1 - 7.3e-85 283.6 0.7 1.9e-84 282.2 0.2 2.1 2 0 0 2 2 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 KXZ49756.1 - 3.5e-81 272.8 0.1 2.8e-80 269.8 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KXZ49756.1 - 4.9e-77 257.5 0.9 6.6e-70 234.3 0.0 4.0 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KXZ49756.1 - 5.8e-57 193.3 15.4 1.5e-56 191.9 15.4 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KXZ49756.1 - 2.4e-53 180.3 0.0 5.8e-53 179.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXZ49756.1 - 1e-40 138.6 0.0 8e-40 135.7 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KXZ49756.1 - 2e-27 95.9 0.2 2.5e-07 30.8 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KXZ49756.1 - 5.7e-24 84.7 0.0 3.1e-23 82.3 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ49756.1 - 1e-16 60.9 0.0 4.3e-16 58.9 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXZ49756.1 - 6.3e-08 33.2 9.0 0.72 10.2 0.0 7.8 6 1 1 7 7 6 2 AAA ATPase domain AAA_22 PF13401.6 KXZ49756.1 - 1.2e-07 32.1 3.6 0.5 10.6 0.0 6.9 6 0 0 6 6 5 2 AAA domain AAA PF00004.29 KXZ49756.1 - 8.7e-06 26.2 0.1 3.1 8.2 0.0 6.1 6 0 0 6 6 6 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KXZ49756.1 - 8.4e-05 22.5 0.5 0.0014 18.5 0.0 3.0 3 0 0 3 3 2 1 RsgA GTPase AAA_18 PF13238.6 KXZ49756.1 - 0.001 19.6 0.2 0.2 12.2 0.0 4.2 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.26 KXZ49756.1 - 0.0045 16.7 0.1 0.4 10.4 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.16 KXZ49756.1 - 0.0053 16.2 1.2 0.051 13.0 0.0 2.8 2 0 0 2 2 2 1 PhoH-like protein DUF3153 PF11353.8 KXZ49756.1 - 0.0091 15.6 2.2 0.1 12.1 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3153) AAA_25 PF13481.6 KXZ49756.1 - 0.013 15.1 2.1 3.1 7.3 0.0 4.0 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 KXZ49756.1 - 0.019 15.3 1.1 5.2 7.5 0.1 3.7 4 0 0 4 4 3 0 RNA helicase T2SSE PF00437.20 KXZ49756.1 - 0.031 13.3 0.0 1.3 8.0 0.0 2.8 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KXZ49756.1 - 0.048 13.0 0.1 0.27 10.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF853 PF05872.12 KXZ49756.1 - 0.052 12.1 2.3 0.47 9.0 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_30 PF13604.6 KXZ49756.1 - 0.073 12.8 6.1 0.75 9.5 0.1 3.8 4 0 0 4 4 3 0 AAA domain AAA_29 PF13555.6 KXZ49756.1 - 0.14 11.9 1.5 20 5.0 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXZ49756.1 - 0.72 10.4 2.2 7.2 7.1 0.1 3.6 4 0 0 4 4 2 0 ABC transporter LUC7 PF03194.15 KXZ49756.1 - 2.6 7.6 20.2 2.6 7.6 3.8 3.8 3 0 0 3 3 3 0 LUC7 N_terminus polyprenyl_synt PF00348.17 KXZ49757.1 - 1.9e-59 200.8 0.2 2.4e-59 200.5 0.2 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase SAPS PF04499.15 KXZ49758.1 - 7.8e-47 160.2 0.0 2.4e-34 119.0 0.0 3.2 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein XPC-binding PF09280.11 KXZ49758.1 - 0.27 11.0 1.0 0.97 9.2 0.0 2.4 3 0 0 3 3 3 0 XPC-binding domain RNA_pol_L_2 PF13656.6 KXZ49759.1 - 7e-29 99.4 0.0 8.3e-29 99.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXZ49759.1 - 5.1e-12 45.1 0.0 6.5e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L36e PF01158.18 KXZ49760.1 - 7.5e-42 141.5 9.2 8.4e-42 141.3 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF2207 PF09972.9 KXZ49760.1 - 0.13 11.0 0.1 0.14 10.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Carboxyl_trans PF01039.22 KXZ49761.1 - 6.6e-20 71.2 1.5 1.4e-19 70.2 1.5 1.5 1 1 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 KXZ49761.1 - 9.5e-06 25.6 1.4 2.1e-05 24.5 1.4 1.6 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain Ldh_1_C PF02866.18 KXZ49762.1 - 1.6e-47 161.6 0.0 3e-47 160.7 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXZ49762.1 - 1.5e-45 154.7 0.4 2.3e-45 154.2 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXZ49762.1 - 0.00033 19.8 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KXZ49762.1 - 0.085 13.3 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain COR PF16095.5 KXZ49764.1 - 2.7e-17 63.2 0.0 6.6e-17 62.0 0.0 1.6 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 KXZ49764.1 - 0.24 11.6 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CAP_N PF01213.19 KXZ49764.1 - 0.97 8.8 6.7 0.44 10.0 3.9 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Ank_4 PF13637.6 KXZ49766.1 - 4.5e-17 62.2 0.3 7.3e-11 42.4 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ49766.1 - 2.3e-12 47.3 0.0 4.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ49766.1 - 1.1e-11 44.7 2.8 8.5e-08 32.3 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49766.1 - 4.1e-11 42.8 0.4 5.1e-05 23.5 0.1 3.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXZ49766.1 - 9.5e-11 41.0 0.2 0.00055 20.2 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat CAMSAP_CC1 PF17095.5 KXZ49768.1 - 0.12 12.3 0.5 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Cyclin_N PF00134.23 KXZ49768.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DNA_methylase PF00145.17 KXZ49769.1 - 2.1e-10 40.5 0.0 1.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Exonuc_VII_L PF02601.15 KXZ49770.1 - 0.013 15.1 60.1 0.19 11.3 27.5 3.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit Abhydrolase_1 PF00561.20 KXZ49772.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ49772.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KXZ49772.1 - 0.076 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXZ49772.1 - 0.089 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF2974 PF11187.8 KXZ49772.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MatE PF01554.18 KXZ49773.1 - 6.6e-45 152.6 24.9 1.9e-24 86.1 10.5 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ49773.1 - 8.8e-09 35.6 0.3 8.8e-09 35.6 0.3 3.4 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 KXZ49773.1 - 0.00012 20.9 1.3 0.00012 20.9 1.3 2.0 2 0 0 2 2 2 1 Lipid II flippase MurJ rve PF00665.26 KXZ49774.1 - 1.8e-13 50.7 0.0 2.6e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KXZ49774.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain GxGYxYP_C PF14323.6 KXZ49774.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain Lipase_3 PF01764.25 KXZ49775.1 - 4e-26 91.6 0.0 5.3e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) DUF2974 PF11187.8 KXZ49775.1 - 0.0014 18.2 0.5 0.075 12.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_8 PF06259.12 KXZ49775.1 - 0.004 16.8 1.6 0.0064 16.1 1.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase NPCBM_assoc PF10633.9 KXZ49775.1 - 0.086 13.1 1.4 0.56 10.5 0.0 2.4 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF2283 PF10049.9 KXZ49776.1 - 4.1e-07 30.1 0.0 0.0037 17.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2283) Secretin_N PF03958.17 KXZ49777.1 - 2.8 8.4 6.6 8 6.9 0.6 3.4 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain DAO PF01266.24 KXZ49778.1 - 1.9e-43 149.4 7.0 2.3e-43 149.1 7.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXZ49778.1 - 0.0017 18.5 0.5 0.0055 16.9 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXZ49778.1 - 0.019 14.2 0.2 0.037 13.3 0.2 1.5 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KXZ49778.1 - 0.11 12.1 1.3 0.27 10.8 1.3 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KXZ49778.1 - 0.23 10.8 0.5 0.39 10.0 0.5 1.3 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 KXZ49778.1 - 0.63 8.7 2.9 6.2 5.4 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein SMC_N PF02463.19 KXZ49780.1 - 1.3e-71 240.6 27.8 1.4e-70 237.1 27.8 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXZ49780.1 - 7.2e-25 87.6 0.0 2.2e-24 86.0 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXZ49780.1 - 3e-12 47.0 0.0 6.6e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXZ49780.1 - 1.2e-10 42.3 8.2 1.2e-10 42.3 8.2 6.1 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 KXZ49780.1 - 8.8e-08 32.3 37.4 1.6e-07 31.4 19.5 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KXZ49780.1 - 2.4e-07 30.4 0.0 5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin PF00261.20 KXZ49780.1 - 3.1e-05 23.5 22.2 3.1e-05 23.5 22.2 6.2 2 2 4 6 6 5 1 Tropomyosin Spc7 PF08317.11 KXZ49780.1 - 0.00022 20.2 24.2 0.00022 20.2 24.2 7.1 3 2 4 7 7 6 4 Spc7 kinetochore protein IFT57 PF10498.9 KXZ49780.1 - 0.0029 16.6 10.1 0.0029 16.6 10.1 4.8 2 2 1 3 3 2 2 Intra-flagellar transport protein 57 ATG16 PF08614.11 KXZ49780.1 - 0.0044 17.3 32.3 0.0044 17.3 32.3 7.0 2 2 4 6 6 3 1 Autophagy protein 16 (ATG16) ABC_tran PF00005.27 KXZ49780.1 - 0.2 12.2 0.0 0.2 12.2 0.0 5.8 3 2 0 3 3 2 0 ABC transporter Osmo_CC PF08946.10 KXZ49780.1 - 0.75 10.1 12.3 0.36 11.1 2.8 4.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil cNMP_binding PF00027.29 KXZ49781.1 - 2.4e-66 219.8 9.2 5.2e-18 64.9 0.2 5.3 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Pkinase PF00069.25 KXZ49781.1 - 6.8e-62 209.2 0.0 2.7e-61 207.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49781.1 - 5.1e-28 98.1 0.0 7.9e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ49781.1 - 8.4e-06 25.3 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DUF5444 PF17519.2 KXZ49781.1 - 0.016 15.2 0.4 26 4.9 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5444) VKOR PF07884.14 KXZ49782.1 - 2.3e-12 47.2 1.5 2.7e-12 47.0 1.5 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Mannosyl_trans3 PF11051.8 KXZ49784.1 - 1.1e-12 47.9 0.0 0.00018 21.0 0.0 3.1 3 0 0 3 3 3 3 Mannosyltransferase putative Scramblase PF03803.15 KXZ49785.1 - 2.6e-09 36.7 0.1 0.00078 18.8 0.2 2.3 2 1 0 2 2 2 2 Scramblase SF3b1 PF08920.10 KXZ49786.1 - 1.3e-35 122.5 2.6 1.3e-35 122.5 2.6 4.8 1 1 2 3 3 3 1 Splicing factor 3B subunit 1 HEAT PF02985.22 KXZ49786.1 - 6.4e-07 29.1 0.3 0.7 10.3 0.0 6.9 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.7 KXZ49786.1 - 1.3e-05 25.3 0.5 0.094 12.8 0.0 4.4 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXZ49786.1 - 2.6e-05 24.5 5.0 0.63 10.5 0.0 5.7 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KXZ49786.1 - 0.00076 19.9 6.3 0.24 11.9 0.0 6.0 6 1 1 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KXZ49786.1 - 0.027 15.1 0.7 7.4 7.2 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 KXZ49786.1 - 0.028 14.2 0.2 0.88 9.3 0.0 2.6 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) RPA_C PF08784.11 KXZ49786.1 - 0.035 14.7 0.8 15 6.3 0.0 3.6 3 0 0 3 3 3 0 Replication protein A C terminal Ribosomal_L6 PF00347.23 KXZ49787.1 - 2.7e-28 98.4 2.4 4.8e-15 56.0 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 MATH PF00917.26 KXZ49788.1 - 2.7e-24 85.5 0.4 5.5e-24 84.5 0.4 1.5 1 0 0 1 1 1 1 MATH domain Draxin PF15550.6 KXZ49788.1 - 4.1 7.2 25.4 13 5.5 25.4 1.8 1 0 0 1 1 1 0 Draxin Atg14 PF10186.9 KXZ49788.1 - 8.7 5.3 25.0 70 2.4 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_S13 PF00416.22 KXZ49789.1 - 1.5e-31 109.5 7.3 7e-30 104.1 7.3 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 KXZ49789.1 - 0.053 13.8 0.6 1.7 8.9 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix motif GCIP PF13324.6 KXZ49790.1 - 0.0031 17.2 2.8 0.0038 16.9 2.8 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 KXZ49790.1 - 0.0067 14.6 14.0 0.0078 14.4 14.0 1.4 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KXZ49790.1 - 0.0069 15.8 12.5 0.0077 15.7 12.5 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KXZ49790.1 - 0.023 12.9 13.3 0.022 13.0 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KXZ49790.1 - 0.031 13.5 12.3 0.028 13.6 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KXZ49790.1 - 0.079 11.2 8.9 0.082 11.2 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KXZ49790.1 - 0.12 11.7 13.1 0.13 11.6 13.1 1.1 1 0 0 1 1 1 0 BUD22 Prothymosin PF03247.14 KXZ49790.1 - 0.18 12.3 22.7 0.27 11.7 22.7 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Mpp10 PF04006.12 KXZ49790.1 - 0.22 10.0 9.7 0.22 9.9 9.7 1.1 1 0 0 1 1 1 0 Mpp10 protein SpoIIIAH PF12685.7 KXZ49790.1 - 0.29 11.0 7.4 0.37 10.6 7.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Vfa1 PF08432.10 KXZ49790.1 - 2.9 8.2 4.7 4.9 7.5 4.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Med8 PF10232.9 KXZ49790.1 - 9.3 5.8 6.5 51 3.3 6.5 2.2 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 EMP70 PF02990.16 KXZ49791.1 - 9.3e-144 479.9 7.6 1.6e-128 429.7 5.1 2.2 2 0 0 2 2 2 2 Endomembrane protein 70 OMP_b-brl PF13505.6 KXZ49791.1 - 1.3 9.1 4.4 0.91 9.6 1.2 2.3 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain ParA PF10609.9 KXZ49792.1 - 4.2e-87 291.7 0.0 1.1e-80 270.7 0.0 2.1 1 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXZ49792.1 - 1.1e-13 51.4 0.0 1.2e-12 48.0 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KXZ49792.1 - 4.2e-06 26.2 0.0 1.4e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 KXZ49792.1 - 5.6e-06 26.4 0.1 5.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KXZ49792.1 - 7.1e-06 25.4 0.5 1.8e-05 24.1 0.2 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KXZ49792.1 - 0.00042 20.0 0.2 0.00089 18.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KXZ49792.1 - 0.00079 18.5 0.2 0.0013 17.8 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 KXZ49792.1 - 0.0019 17.7 0.1 0.0047 16.4 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KXZ49792.1 - 0.0024 17.7 0.2 1 9.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ49792.1 - 0.0046 17.4 0.5 0.0073 16.7 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KXZ49792.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 KXZ49792.1 - 0.028 13.9 0.0 0.094 12.1 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 KXZ49792.1 - 0.045 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KXZ49792.1 - 0.055 13.4 0.3 0.086 12.8 0.3 1.3 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.10 KXZ49792.1 - 0.056 12.9 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 KXZ49792.1 - 0.067 12.9 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein SRP54 PF00448.22 KXZ49792.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KXZ49792.1 - 0.089 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KXZ49792.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 KXZ49792.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 KXZ49792.1 - 0.19 11.6 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 NTPase Ribosomal_S16 PF00886.19 KXZ49793.1 - 4e-21 74.8 0.2 7.8e-21 73.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S16 Pkinase PF00069.25 KXZ49794.1 - 1.3e-55 188.6 0.0 3.3e-35 121.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49794.1 - 2.2e-24 86.2 0.0 3e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ49794.1 - 0.0061 15.9 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S9 PF00326.21 KXZ49795.1 - 1.4e-21 77.0 0.0 2.6e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KXZ49795.1 - 8e-15 54.5 0.0 1.9e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 KXZ49795.1 - 0.028 13.7 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RRM_1 PF00076.22 KXZ49796.1 - 6.6e-24 83.5 3.8 1.8e-07 30.9 0.2 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXZ49796.1 - 0.00011 22.2 0.2 0.034 14.2 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif PHM7_cyt PF14703.6 KXZ49796.1 - 0.00098 19.4 2.7 6.1 7.0 0.0 4.1 3 2 0 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter BRAP2 PF07576.12 KXZ49796.1 - 0.0079 16.4 0.0 2.9 8.2 0.0 2.7 3 0 0 3 3 3 2 BRCA1-associated protein 2 SET_assoc PF11767.8 KXZ49796.1 - 0.031 13.9 0.5 7.7 6.2 0.1 3.5 3 1 0 3 3 3 0 Histone lysine methyltransferase SET associated B9-C2 PF07162.11 KXZ49797.1 - 1.4e-24 87.2 0.0 2.1e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ig_3 PF13927.6 KXZ49797.1 - 8e-11 42.4 0.0 1.6e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KXZ49797.1 - 8.8e-11 41.7 0.1 1.5e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KXZ49797.1 - 4.9e-08 33.2 0.0 7.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KXZ49797.1 - 0.00015 21.9 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KXZ49797.1 - 0.0033 17.6 0.1 0.034 14.3 0.1 2.1 1 1 1 2 2 2 1 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.15 KXZ49797.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 CBP PF12192.8 KXZ49797.1 - 0.069 13.4 0.5 0.62 10.3 0.1 2.5 2 0 0 2 2 2 0 Fungal calcium binding protein Ig_4 PF16680.5 KXZ49797.1 - 0.26 11.6 0.0 0.44 10.8 0.0 1.3 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Ax_dynein_light PF10211.9 KXZ49799.1 - 2e-81 272.4 13.7 3.5e-81 271.7 13.7 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain ADK PF00406.22 KXZ49799.1 - 2.4e-48 164.0 0.2 6.5e-48 162.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 KXZ49799.1 - 2.4e-28 99.3 0.7 2e-27 96.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain CP12 PF02672.15 KXZ49799.1 - 6e-07 30.1 0.2 6e-07 30.1 0.2 3.3 3 1 0 3 3 3 1 CP12 domain AAA_18 PF13238.6 KXZ49799.1 - 2.8e-05 24.7 0.0 0.0001 22.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KXZ49799.1 - 4e-05 23.4 2.4 0.048 13.3 0.0 3.8 4 1 0 4 4 4 2 Thymidylate kinase ADIP PF11559.8 KXZ49799.1 - 0.0002 21.5 8.5 0.0002 21.5 8.5 1.9 3 0 0 3 3 1 1 Afadin- and alpha -actinin-Binding Hydin_ADK PF17213.3 KXZ49799.1 - 0.0012 19.2 3.7 0.0045 17.3 0.1 2.9 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain NTPase_1 PF03266.15 KXZ49799.1 - 0.019 14.9 3.5 0.2 11.5 0.0 3.3 3 1 1 4 4 4 0 NTPase Lzipper-MIP1 PF14389.6 KXZ49799.1 - 0.037 14.3 6.5 4.6 7.6 0.1 3.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF3038 PF11237.8 KXZ49799.1 - 0.056 13.5 0.6 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) AAA_33 PF13671.6 KXZ49799.1 - 0.11 12.6 6.0 0.47 10.6 0.5 3.8 3 1 0 3 3 3 0 AAA domain ADK_lid PF05191.14 KXZ49799.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid Jnk-SapK_ap_N PF09744.9 KXZ49799.1 - 0.37 11.0 15.8 0.087 13.1 9.3 2.4 3 0 0 3 3 2 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 KXZ49799.1 - 0.5 10.7 11.6 0.16 12.3 8.4 1.8 2 0 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Syntaxin-6_N PF09177.11 KXZ49799.1 - 0.63 10.6 7.5 0.29 11.7 4.3 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 KXZ49799.1 - 1 7.2 3.6 2.6 5.8 3.5 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family STAT_alpha PF01017.20 KXZ49799.1 - 1.3 8.9 11.2 0.14 12.0 6.0 1.9 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF5320 PF17253.2 KXZ49799.1 - 3 8.9 5.6 4.9 8.3 1.6 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DivIC PF04977.15 KXZ49799.1 - 3.5 7.5 11.1 0.093 12.5 1.1 3.0 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.10 KXZ49799.1 - 5.2 7.3 8.6 0.61 10.3 1.5 2.8 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Metallophos PF00149.28 KXZ49800.1 - 1.7e-37 129.9 0.0 2.4e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXZ49800.1 - 0.0062 16.9 0.2 0.017 15.5 0.2 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KXZ49800.1 - 0.079 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Gp_dh_C PF02800.20 KXZ49801.1 - 8.1e-70 233.5 0.2 8.1e-70 233.5 0.2 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXZ49801.1 - 1.1e-37 128.5 0.1 2.3e-37 127.4 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXZ49801.1 - 0.025 13.9 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 KXZ49801.1 - 0.026 14.7 2.0 0.047 13.8 0.5 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ACT_4 PF13291.6 KXZ49801.1 - 0.14 12.7 0.0 0.62 10.7 0.0 2.0 2 0 0 2 2 2 0 ACT domain KIAA1430 PF13879.6 KXZ49802.1 - 6.3e-12 46.2 0.7 6.3e-12 46.2 0.7 4.8 5 1 0 5 5 5 2 KIAA1430 homologue DUF4490 PF14892.6 KXZ49803.1 - 5e-09 36.2 0.2 7.4e-09 35.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) NTP_transf_3 PF12804.7 KXZ49803.1 - 0.00027 21.3 0.6 0.00027 21.3 0.6 2.5 1 1 1 2 2 2 1 MobA-like NTP transferase domain Pro_CA PF00484.19 KXZ49804.1 - 2.2e-32 112.5 0.1 2.7e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF3335 PF11814.8 KXZ49804.1 - 0.089 12.3 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family AAA_13 PF13166.6 KXZ49805.1 - 3.9e-05 22.5 17.6 3.9e-05 22.5 17.6 3.6 2 2 1 3 3 3 2 AAA domain CENP-F_leu_zip PF10473.9 KXZ49805.1 - 0.0094 16.0 8.0 0.0094 16.0 8.0 7.0 2 2 3 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 KXZ49805.1 - 0.015 14.8 72.8 0.098 12.1 9.4 5.3 2 2 3 6 6 6 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KXZ49805.1 - 0.37 9.6 92.8 0.016 14.1 15.5 6.1 2 2 5 7 7 7 0 Spc7 kinetochore protein MSG PF02349.15 KXZ49805.1 - 3.6 7.8 7.5 0.73 10.1 2.4 2.7 2 1 0 2 2 2 0 Major surface glycoprotein FlaC_arch PF05377.11 KXZ49805.1 - 6.6 7.2 21.4 25 5.3 0.0 8.1 8 2 1 9 9 9 0 Flagella accessory protein C (FlaC) DUF883 PF05957.13 KXZ49806.1 - 0.016 15.8 15.2 0.016 15.8 15.2 17.4 5 3 8 15 15 15 0 Bacterial protein of unknown function (DUF883) DUF5583 PF17821.1 KXZ49806.1 - 0.69 9.9 2.8 1 9.3 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5583) 2OG-FeII_Oxy PF03171.20 KXZ49807.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FATC PF02260.20 KXZ49807.1 - 0.28 11.0 1.1 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 FATC domain DUF1772 PF08592.11 KXZ49808.1 - 6.4e-13 49.2 6.2 8.9e-13 48.7 6.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DDT PF02791.17 KXZ49808.1 - 0.039 14.3 0.3 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 DDT domain VPS13 PF16908.5 KXZ49809.1 - 6.3e-49 166.9 0.0 1.4e-48 165.7 0.0 1.6 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KXZ49809.1 - 1.8e-31 108.7 0.0 3.2e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Vps62 PF06101.11 KXZ49809.1 - 1e-21 76.9 0.1 8.8e-06 24.3 0.0 5.1 4 1 0 5 5 5 5 Vacuolar protein sorting-associated protein 62 VPS13_mid_rpt PF16910.5 KXZ49809.1 - 1.3e-15 57.5 0.0 5.5e-12 45.6 0.0 3.8 4 0 0 4 4 4 1 Repeating coiled region of VPS13 Pex24p PF06398.11 KXZ49809.1 - 0.01 14.9 8.4 0.014 14.4 8.4 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin LPP PF04728.13 KXZ49810.1 - 0.00062 20.1 0.3 0.00091 19.6 0.3 1.3 1 0 0 1 1 1 1 Lipoprotein leucine-zipper Sec34 PF04136.15 KXZ49810.1 - 0.035 14.0 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Sec34-like family Baculo_gp64 PF03273.13 KXZ49810.1 - 0.081 11.7 0.0 0.081 11.7 0.0 1.0 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family HALZ PF02183.18 KXZ49810.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase_Tyr PF07714.17 KXZ49811.1 - 2.5e-35 122.0 0.0 5.5e-30 104.5 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ49811.1 - 2.2e-31 109.2 0.0 1.2e-28 100.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49811.1 - 1e-05 24.5 0.0 1.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SlyX PF04102.12 KXZ49812.1 - 1.2e-06 29.0 10.9 2.6e-06 27.9 10.9 1.6 1 0 0 1 1 1 1 SlyX Spc29 PF17082.5 KXZ49812.1 - 0.00044 20.2 0.8 0.003 17.4 1.0 1.8 1 1 0 2 2 2 1 Spindle Pole Component 29 FliD_C PF07195.12 KXZ49812.1 - 0.00054 19.5 0.6 0.00054 19.5 0.6 1.4 2 0 0 2 2 1 1 Flagellar hook-associated protein 2 C-terminus Spc7 PF08317.11 KXZ49812.1 - 0.00085 18.3 2.3 0.0011 18.0 2.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Speriolin_C PF15059.6 KXZ49812.1 - 0.001 19.2 0.2 0.083 13.0 0.0 2.3 2 0 0 2 2 2 1 Speriolin C-terminus ZapB PF06005.12 KXZ49812.1 - 0.0025 18.2 5.3 0.025 15.0 6.4 2.0 2 0 0 2 2 2 1 Cell division protein ZapB T4SS PF07996.11 KXZ49812.1 - 0.0032 17.9 10.7 0.0044 17.4 10.7 1.3 1 0 0 1 1 1 1 Type IV secretion system proteins DUF4407 PF14362.6 KXZ49812.1 - 0.0051 16.2 5.1 0.0067 15.8 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF16 PF01519.16 KXZ49812.1 - 0.011 16.2 4.0 0.022 15.3 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KXZ49812.1 - 0.016 15.4 3.5 0.035 14.3 3.5 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 KXZ49812.1 - 0.017 13.7 1.4 0.022 13.4 1.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FAM76 PF16046.5 KXZ49812.1 - 0.019 14.3 0.5 0.026 13.9 0.5 1.2 1 0 0 1 1 1 0 FAM76 protein POTRA_2 PF08479.11 KXZ49812.1 - 0.019 14.8 3.2 0.039 13.8 3.2 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type DUF3573 PF12097.8 KXZ49812.1 - 0.024 13.5 2.2 0.031 13.1 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF2730 PF10805.8 KXZ49812.1 - 0.025 14.7 1.5 0.093 12.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Csm1_N PF18504.1 KXZ49812.1 - 0.047 14.0 5.1 0.11 12.8 5.1 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain HAP1_N PF04849.13 KXZ49812.1 - 0.047 12.9 6.0 0.069 12.4 6.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region USP8_interact PF08941.10 KXZ49812.1 - 0.051 13.4 4.0 0.078 12.8 4.0 1.3 1 0 0 1 1 1 0 USP8 interacting DUF4094 PF13334.6 KXZ49812.1 - 0.056 13.9 1.1 0.1 13.0 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) PspA_IM30 PF04012.12 KXZ49812.1 - 0.057 13.0 8.0 0.1 12.1 8.0 1.4 1 0 0 1 1 1 0 PspA/IM30 family Spc24 PF08286.11 KXZ49812.1 - 0.069 13.4 1.1 0.11 12.8 1.1 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 KXZ49812.1 - 0.069 13.6 2.9 0.17 12.4 2.9 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TFIIA PF03153.13 KXZ49812.1 - 0.13 12.2 6.7 0.14 12.1 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DivIC PF04977.15 KXZ49812.1 - 0.16 11.8 9.6 0.49 10.2 9.8 1.7 2 0 0 2 2 1 0 Septum formation initiator Mod_r PF07200.13 KXZ49812.1 - 0.32 11.1 9.6 0.14 12.2 7.4 1.5 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein DASH_Spc34 PF08657.10 KXZ49812.1 - 0.42 10.4 5.8 0.33 10.7 4.1 1.6 2 0 0 2 2 2 0 DASH complex subunit Spc34 RRP36 PF06102.12 KXZ49812.1 - 0.48 10.4 7.9 0.84 9.6 7.9 1.4 1 1 0 1 1 1 0 rRNA biogenesis protein RRP36 MCPVI PF02993.14 KXZ49812.1 - 0.64 9.8 7.8 0.19 11.5 4.4 1.7 1 1 1 2 2 2 0 Minor capsid protein VI DUF4763 PF15960.5 KXZ49812.1 - 0.73 9.1 10.0 0.83 8.9 8.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Prefoldin PF02996.17 KXZ49812.1 - 0.79 9.6 10.2 0.61 10.0 8.4 1.6 2 0 0 2 2 1 0 Prefoldin subunit ABC_tran_CTD PF16326.5 KXZ49812.1 - 0.96 9.7 9.5 1.3 9.3 6.9 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain Rho_Binding PF08912.11 KXZ49812.1 - 1 10.2 11.6 3.5 8.5 11.6 1.8 1 1 0 1 1 1 0 Rho Binding DUF3251 PF11622.8 KXZ49812.1 - 1.1 8.8 11.1 1.7 8.2 10.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) AAA_13 PF13166.6 KXZ49812.1 - 1.4 7.5 5.7 1.4 7.5 4.5 1.3 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.9 KXZ49812.1 - 1.6 7.7 8.4 3.6 6.6 7.2 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 KXZ49812.1 - 4.4 7.7 18.3 2.5 8.5 15.5 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TSC22 PF01166.18 KXZ49812.1 - 7.2 7.0 6.8 15 6.0 5.3 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family TPR_2 PF07719.17 KXZ49813.1 - 0.0019 18.2 44.3 0.0042 17.1 0.5 9.9 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ49813.1 - 0.019 15.1 2.0 0.019 15.1 2.0 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ49813.1 - 0.05 14.4 0.0 0.05 14.4 0.0 12.6 10 4 4 14 14 14 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ49813.1 - 0.05 13.3 22.7 1.1 9.0 0.3 6.6 6 1 1 7 7 7 0 TPR repeat TPR_1 PF00515.28 KXZ49813.1 - 0.1 12.4 0.2 0.1 12.4 0.2 7.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ49813.1 - 0.13 12.5 21.5 2.7 8.4 1.3 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ49813.1 - 0.2 12.1 10.0 1.8 9.1 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ49813.1 - 0.3 11.2 11.5 0.76 9.9 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ49813.1 - 0.44 11.1 0.1 0.065 13.7 3.6 8.9 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ49814.1 - 5.6e-15 54.7 12.4 7.6e-07 28.7 0.0 6.2 6 0 0 6 6 6 3 TPR repeat TPR_1 PF00515.28 KXZ49814.1 - 1.5e-12 46.8 20.9 0.0023 17.7 1.9 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ49814.1 - 2.5e-09 36.5 58.4 0.00075 19.4 3.2 12.1 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ49814.1 - 7.7e-09 35.7 12.2 2.4e-06 27.9 1.1 13.2 9 6 5 14 14 13 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ49814.1 - 9.4e-09 35.8 23.3 5.3e-06 27.0 6.7 11.4 8 4 4 12 12 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ49814.1 - 3.7e-08 33.2 11.4 0.031 14.7 0.0 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ49814.1 - 7.8e-07 28.8 10.0 0.25 11.6 0.4 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ49814.1 - 2.6e-06 27.9 21.4 0.00074 20.0 5.3 9.2 7 4 2 9 9 9 4 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ49814.1 - 0.0011 18.3 1.4 0.0011 18.3 1.4 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ49814.1 - 0.018 15.6 6.5 0.018 15.6 6.5 12.4 12 1 1 13 13 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ49814.1 - 0.062 13.6 0.3 0.062 13.6 0.3 10.3 8 4 2 11 11 10 0 Tetratricopeptide repeat PPR PF01535.20 KXZ49814.1 - 0.19 12.1 0.2 9.4 6.7 0.0 3.7 4 0 0 4 4 3 0 PPR repeat TPR_6 PF13174.6 KXZ49814.1 - 0.33 11.7 0.0 0.33 11.7 0.0 8.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ49814.1 - 0.58 10.3 31.8 0.94 9.7 0.1 9.0 11 0 0 11 11 10 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ49814.1 - 0.92 9.8 14.0 1.6 9.0 2.7 4.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AP2 PF00847.20 KXZ49815.1 - 7.1e-06 26.2 4.8 0.057 13.7 0.1 4.0 4 0 0 4 4 4 2 AP2 domain SDA1 PF05285.12 KXZ49815.1 - 0.0083 15.6 10.8 0.012 15.1 10.8 1.2 1 0 0 1 1 1 1 SDA1 Mur_ligase_C PF02875.21 KXZ49815.1 - 0.14 12.4 0.0 0.51 10.6 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain BUD22 PF09073.10 KXZ49815.1 - 0.24 10.7 8.3 0.33 10.2 8.3 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KXZ49815.1 - 4.2 5.5 15.9 5.6 5.0 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXZ49815.1 - 6.1 5.0 7.5 8.3 4.6 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 KXZ49815.1 - 9.5 5.5 16.6 17 4.7 16.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Vasohibin PF14822.6 KXZ49816.1 - 8.2e-57 192.2 0.0 1.2e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Vasohibin Glyco_transf_49 PF13896.6 KXZ49816.1 - 8.4e-40 137.1 0.0 9.6e-34 117.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan SNF2_N PF00176.23 KXZ49817.1 - 1.1e-08 34.2 0.0 1.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Med15 PF09606.10 KXZ49818.1 - 8.2 5.0 11.8 9.9 4.7 11.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAST_1 PF06743.15 KXZ49819.1 - 4.1e-09 36.3 0.7 0.18 11.7 0.0 5.0 4 0 0 4 4 4 4 FAST kinase-like protein, subdomain 1 Myb_CC_LHEQLE PF14379.6 KXZ49820.1 - 1.3e-13 50.4 10.0 1.3e-13 50.4 10.0 2.5 2 0 0 2 2 2 1 MYB-CC type transfactor, LHEQLE motif Myb_DNA-binding PF00249.31 KXZ49820.1 - 8.3e-08 32.3 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain CReP_N PF10472.9 KXZ49821.1 - 0.15 10.9 0.2 0.2 10.5 0.2 1.1 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor PepSY_TM PF03929.16 KXZ49821.1 - 0.56 9.8 3.9 0.76 9.4 0.6 2.0 1 1 1 2 2 2 0 PepSY-associated TM region CAP_N PF01213.19 KXZ49821.1 - 1.8 8.0 6.2 2.6 7.4 6.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aconitase PF00330.20 KXZ49823.1 - 9.3e-80 268.9 0.1 2.1e-77 261.1 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Pkinase PF00069.25 KXZ49824.1 - 2.6e-48 164.7 0.0 3.6e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49824.1 - 1.6e-20 73.5 0.0 2.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ49824.1 - 0.048 13.0 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXZ49824.1 - 0.048 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2229 PF09989.9 KXZ49824.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) HMGL-like PF00682.19 KXZ49825.1 - 2.4e-56 191.2 0.2 2.4e-56 191.2 0.2 1.7 2 0 0 2 2 2 1 HMGL-like DUF3145 PF11343.8 KXZ49825.1 - 0.051 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) RXLR PF16810.5 KXZ49826.1 - 0.16 12.4 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity TPR_12 PF13424.6 KXZ49827.1 - 3.4e-72 238.7 55.0 7.8e-18 64.5 1.7 5.5 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ49827.1 - 1.7e-57 189.8 40.6 5.4e-12 45.2 0.6 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ49827.1 - 1.1e-17 63.0 13.7 0.02 14.7 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ49827.1 - 3.7e-14 51.6 27.1 0.006 16.5 0.1 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ49827.1 - 2.5e-12 45.9 29.4 0.031 14.4 0.0 7.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ49827.1 - 5.8e-11 41.7 8.1 0.26 11.6 0.3 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ49827.1 - 6.6e-10 38.9 14.2 1.1e-09 38.2 13.1 1.9 1 1 0 1 1 1 1 MalT-like TPR region TPR_4 PF07721.14 KXZ49827.1 - 8.4e-09 35.2 67.4 0.023 15.3 2.0 9.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ49827.1 - 8.6e-09 35.9 28.8 3.7e-05 24.3 6.0 8.5 3 2 4 8 8 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ49827.1 - 3.1e-06 27.5 56.4 0.12 13.2 0.7 9.4 2 1 7 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ49827.1 - 0.00055 20.4 29.7 0.004 17.6 2.5 6.0 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ49827.1 - 0.00072 19.8 13.1 2 9.0 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 KXZ49827.1 - 0.015 15.3 0.4 25 5.0 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KXZ49827.1 - 1.8 8.5 10.4 27 4.6 0.1 4.6 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal FAD_binding_3 PF01494.19 KXZ49828.1 - 1e-12 48.0 4.3 1.6e-05 24.4 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain Thi4 PF01946.17 KXZ49828.1 - 2.9e-05 23.5 0.1 4.9e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXZ49828.1 - 5.3e-05 22.4 0.5 9.8e-05 21.6 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXZ49828.1 - 0.00015 21.8 0.2 0.00034 20.6 0.2 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXZ49828.1 - 0.00026 21.1 0.2 0.00082 19.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ49828.1 - 0.0014 18.2 1.7 0.0018 17.9 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ49828.1 - 0.029 13.6 0.4 0.045 13.0 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXZ49828.1 - 0.056 12.5 0.0 8 5.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 KXZ49828.1 - 0.099 11.3 0.6 0.15 10.8 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXZ49828.1 - 0.13 11.5 0.6 0.25 10.6 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ49828.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TetR_C_7 PF14246.6 KXZ49828.1 - 0.27 11.3 1.3 5.5 7.0 0.1 3.0 3 0 0 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Fasciclin PF02469.22 KXZ49829.1 - 1.4e-52 177.3 8.3 1.8e-17 63.7 0.0 3.1 3 0 0 3 3 3 3 Fasciclin domain DUF4465 PF14717.6 KXZ49829.1 - 0.12 12.8 1.8 0.22 11.9 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4465) DUF3638 PF12340.8 KXZ49831.1 - 1.3e-60 204.6 0.0 2.2e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXZ49831.1 - 4.6e-13 48.3 0.1 1.3e-12 46.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) BTG PF07742.12 KXZ49831.1 - 0.2 11.5 0.1 6.2 6.7 0.0 3.1 3 0 0 3 3 3 0 BTG family Spc42p PF11544.8 KXZ49831.1 - 0.37 10.8 0.8 1.8 8.6 0.4 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p Atg14 PF10186.9 KXZ49831.1 - 0.8 8.7 2.4 1.5 7.9 2.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rod_cone_degen PF15201.6 KXZ49833.1 - 0.0049 16.9 0.8 0.018 15.1 0.8 2.0 1 0 0 1 1 1 1 Progressive rod-cone degeneration Na_H_Exchanger PF00999.21 KXZ49834.1 - 3.2e-51 174.3 45.3 5.5e-40 137.3 27.4 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family DUF3043 PF11241.8 KXZ49834.1 - 0.00072 19.6 0.3 0.0019 18.3 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3043) DUF3915 PF13054.6 KXZ49834.1 - 0.013 15.5 6.3 0.034 14.1 6.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 KXZ49834.1 - 0.33 9.2 17.5 0.53 8.5 17.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family CDC45 PF02724.14 KXZ49834.1 - 5.1 5.3 4.7 7.6 4.7 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Dishevelled PF02377.15 KXZ49834.1 - 9.5 6.7 12.5 0.48 10.9 6.9 1.6 2 0 0 2 2 2 0 Dishevelled specific domain Ribonuc_red_lgC PF02867.15 KXZ49835.1 - 9.1e-183 608.5 0.0 1.2e-182 608.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KXZ49835.1 - 1.7e-22 79.2 0.0 4e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KXZ49835.1 - 2.3e-17 63.3 0.0 6.9e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Ly-6_related PF06579.12 KXZ49835.1 - 0.05 13.8 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein DEAD PF00270.29 KXZ49836.1 - 2e-15 57.0 0.0 3.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ49836.1 - 1.2e-12 48.2 0.0 2.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.10 KXZ49836.1 - 1.9e-11 43.7 0.0 4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 KXZ49836.1 - 4.6e-10 39.3 0.1 1.3e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 KXZ49836.1 - 5.9e-05 23.7 0.0 0.00014 22.5 0.0 1.6 1 0 0 1 1 1 1 RecQ zinc-binding HTH_40 PF14493.6 KXZ49836.1 - 0.00013 22.3 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain ResIII PF04851.15 KXZ49836.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPT PF03151.16 KXZ49837.1 - 7.9e-12 45.1 11.5 9.3e-12 44.9 11.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ49837.1 - 1.5e-09 38.1 26.3 2.5e-05 24.4 11.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 KXZ49837.1 - 0.56 8.4 5.8 0.15 10.3 3.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) EIF_2_alpha PF07541.12 KXZ49838.1 - 1.7e-39 134.5 0.1 3.3e-39 133.6 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KXZ49838.1 - 4.9e-18 65.2 0.4 1.1e-17 64.1 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Guanylate_cyc PF00211.20 KXZ49839.1 - 1.2e-43 148.8 0.0 2.3e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 KXZ49839.1 - 6.6e-12 45.7 4.0 1.1e-11 45.0 4.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Pkinase_Tyr PF07714.17 KXZ49839.1 - 6.5e-05 22.3 0.0 0.002 17.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ49839.1 - 0.026 13.9 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Ycf54 PF10674.9 KXZ49840.1 - 7.2e-28 96.7 0.2 1e-27 96.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2488) TFCD_C PF12612.8 KXZ49841.1 - 7.5e-24 84.6 0.0 2.7e-23 82.8 0.0 2.0 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal Cnd1 PF12717.7 KXZ49841.1 - 0.081 13.0 0.0 53 3.8 0.0 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 GRDP-like PF07173.12 KXZ49843.1 - 6.8e-15 56.0 0.3 1.4e-10 42.0 0.0 2.3 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like ATG16 PF08614.11 KXZ49844.1 - 0.014 15.7 4.2 0.016 15.4 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 KXZ49845.1 - 0.0076 16.6 11.5 0.055 13.8 11.5 2.1 1 1 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FapA PF03961.13 KXZ49845.1 - 0.13 10.8 0.5 0.13 10.8 0.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2203 PF09969.9 KXZ49845.1 - 1.1 9.9 5.2 23 5.8 0.0 2.5 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spc7_N PF15402.6 KXZ49845.1 - 1.4 7.1 5.0 1.6 6.9 5.0 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CCDC-167 PF15188.6 KXZ49845.1 - 1.9 8.9 8.2 5 7.5 8.0 1.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 ERM PF00769.19 KXZ49845.1 - 2.8 7.7 22.0 32 4.2 22.2 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FUSC PF04632.12 KXZ49845.1 - 8.1 4.8 11.8 10 4.5 11.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GRDP-like PF07173.12 KXZ49846.1 - 0.013 16.2 0.0 0.015 16.0 0.0 1.0 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like Enkurin PF13864.6 KXZ49847.1 - 0.038 14.4 10.1 0.069 13.6 0.1 2.8 2 1 0 2 2 2 0 Calmodulin-binding ALIX_LYPXL_bnd PF13949.6 KXZ49847.1 - 0.31 10.3 14.7 0.54 9.5 14.3 1.5 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV GIT_CC PF16559.5 KXZ49847.1 - 0.34 10.8 9.8 1.3 8.9 0.1 3.6 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 KXZ49847.1 - 0.57 10.3 16.3 0.91 9.6 2.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KXZ49847.1 - 1.8 8.7 7.3 1.4 9.1 0.5 2.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Sec34 PF04136.15 KXZ49847.1 - 1.9 8.3 10.5 0.17 11.7 1.9 2.2 2 0 0 2 2 2 0 Sec34-like family HIP1_clath_bdg PF16515.5 KXZ49847.1 - 2 9.1 23.3 0.61 10.7 7.1 3.1 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_leu_zip PF10473.9 KXZ49847.1 - 2 8.4 25.4 4.4 7.3 10.3 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 KXZ49847.1 - 2.8 7.1 10.8 0.98 8.6 1.1 2.3 2 1 0 2 2 2 0 TMPIT-like protein DUF2730 PF10805.8 KXZ49847.1 - 3.8 7.7 8.9 0.71 10.0 0.8 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) APG6_N PF17675.1 KXZ49847.1 - 5.9 7.4 40.0 18 5.9 18.2 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 KXZ49847.1 - 6.8 6.7 18.6 3.6 7.6 3.4 3.5 2 2 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 KXZ49847.1 - 8.7 6.4 14.6 3.4 7.7 0.9 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) YabA PF06156.13 KXZ49847.1 - 9 7.0 15.4 2.4 8.8 2.7 2.9 2 1 0 2 2 2 0 Initiation control protein YabA GcpE PF04551.14 KXZ49849.1 - 7.3e-153 508.8 0.0 1.4e-152 507.8 0.0 1.5 1 1 0 1 1 1 1 GcpE protein Sgf11 PF08209.11 KXZ49849.1 - 0.32 10.6 1.7 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) UBA PF00627.31 KXZ49851.1 - 0.0017 18.2 0.0 0.0076 16.1 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain STI1 PF17830.1 KXZ49852.1 - 1.5e-14 53.7 5.2 1.7e-05 24.6 0.0 3.8 3 1 0 3 3 3 3 STI1 domain LPD22 PF18834.1 KXZ49852.1 - 0.026 14.7 0.8 0.96 9.7 0.1 3.1 3 1 0 3 3 3 0 Large polyvalent protein associated domain 22 Suv3_C_1 PF18147.1 KXZ49852.1 - 0.17 11.8 2.0 7.5 6.5 0.1 3.6 4 0 0 4 4 4 0 Suv3 C-terminal domain 1 ubiquitin PF00240.23 KXZ49853.1 - 3.6e-172 558.5 24.0 1e-33 114.9 0.4 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KXZ49853.1 - 4.6e-82 269.9 26.2 9e-16 57.5 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXZ49853.1 - 5e-29 100.6 11.8 0.00052 20.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KXZ49853.1 - 5.5e-19 67.9 6.8 0.051 13.5 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KXZ49853.1 - 4.2e-17 62.6 1.8 0.35 11.5 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXZ49853.1 - 6e-17 61.7 5.4 0.2 11.8 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXZ49853.1 - 1.1e-16 61.0 13.4 0.068 13.5 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KXZ49853.1 - 2.1e-09 37.0 2.7 1.1 8.6 0.0 4.3 4 0 0 4 4 4 4 RNA methyltransferase DUF3861 PF12977.7 KXZ49853.1 - 7e-08 32.5 5.4 12 6.1 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) Ubiquitin_4 PF18036.1 KXZ49853.1 - 1.6e-07 31.2 32.6 15 5.7 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 KXZ49853.1 - 1.1e-06 29.3 0.2 63 4.4 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KXZ49853.1 - 2e-06 27.9 7.5 6.5 6.9 0.0 5.0 5 0 0 5 5 5 4 UDP-glucose:Glycoprotein Glucosyltransferase DUF2870 PF11069.8 KXZ49853.1 - 2.1e-06 28.0 0.0 66 4.0 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KXZ49853.1 - 6.4e-06 25.9 7.2 19 5.2 0.0 5.3 5 0 0 5 5 5 0 ACT domain ACT_4 PF13291.6 KXZ49853.1 - 1.5e-05 25.5 1.9 76 4.0 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF969 PF06149.12 KXZ49853.1 - 1.7e-05 24.4 0.4 27 4.1 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ORF11CD3 PF10549.9 KXZ49853.1 - 0.0039 17.3 0.0 2e+02 2.2 0.0 5.3 5 0 0 5 5 5 0 ORF11CD3 domain DUF493 PF04359.14 KXZ49853.1 - 0.0064 17.1 0.2 3.3e+02 1.9 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ProRS-C_2 PF09181.10 KXZ49853.1 - 0.0095 16.0 9.9 72 3.6 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Phage_sheath_1N PF17481.2 KXZ49853.1 - 0.05 14.1 11.1 37 4.9 0.7 4.9 1 1 2 4 4 4 0 Phage tail sheath protein beta-sandwich domain Pullulanase_N2 PF17967.1 KXZ49853.1 - 0.13 13.2 0.1 4.6e+02 1.7 0.0 4.0 4 0 0 4 4 4 0 Pullulanase N2 domain YcgR_2 PF12945.7 KXZ49853.1 - 0.19 11.9 8.1 1.7e+02 2.4 0.1 5.0 5 0 0 5 5 5 0 Flagellar protein YcgR Tash_PEST PF07708.11 KXZ49853.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif FlgD_ig PF13860.6 KXZ49853.1 - 1.7 8.5 12.8 1.3e+02 2.5 0.1 5.2 5 0 0 5 5 5 0 FlgD Ig-like domain PI3K_p85B PF02192.16 KXZ49853.1 - 4 7.2 14.0 1.1e+02 2.7 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain C2 PF00168.30 KXZ49854.1 - 2.6e-11 43.7 0.0 3.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain LysM PF01476.20 KXZ49854.1 - 8.6e-05 22.5 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain Methyltransf_21 PF05050.12 KXZ49856.1 - 2.3e-14 53.8 0.0 3.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain HEAT PF02985.22 KXZ49857.1 - 4e-06 26.6 5.3 9.3 6.8 0.0 6.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 KXZ49857.1 - 0.0019 18.6 1.2 0.0019 18.6 1.2 6.7 6 1 1 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 KXZ49857.1 - 0.0093 16.3 14.5 0.011 16.1 0.1 4.7 4 1 0 4 4 4 1 HEAT repeats Arm PF00514.23 KXZ49857.1 - 0.032 14.3 2.2 55 4.0 0.1 4.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KXZ49857.1 - 0.034 13.7 0.0 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 CLASP N terminal ParcG PF10274.9 KXZ49857.1 - 0.26 11.4 0.0 23 5.1 0.0 2.3 2 0 0 2 2 2 0 Parkin co-regulated protein IBN_N PF03810.19 KXZ49858.1 - 2.1e-08 34.0 0.0 5.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 KXZ49858.1 - 1.1e-05 25.9 0.4 1.1e-05 25.9 0.4 3.6 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 KXZ49858.1 - 0.00068 19.7 2.5 0.18 12.1 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KXZ49858.1 - 0.0028 18.0 12.6 0.04 14.3 1.1 3.1 2 1 1 3 3 3 2 HEAT repeats Importin_rep_4 PF18808.1 KXZ49858.1 - 0.15 12.3 0.0 1.5 9.1 0.0 2.6 2 1 0 2 2 2 0 Importin repeat DUF563 PF04577.14 KXZ49859.1 - 2e-07 31.4 0.0 7.9e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Ribonuc_red_sm PF00268.21 KXZ49860.1 - 4e-119 397.2 0.1 5.2e-119 396.8 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 KXZ49860.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain adh_short PF00106.25 KXZ49861.1 - 1.3e-20 73.7 0.0 3e-10 39.9 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ49861.1 - 2.7e-10 40.2 0.0 7.5e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ49861.1 - 0.017 15.1 0.1 0.1 12.5 0.1 2.1 2 1 0 2 2 2 0 KR domain adh_short PF00106.25 KXZ49862.1 - 4.7e-23 81.7 0.1 2.5e-12 46.7 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ49862.1 - 2.1e-11 43.8 0.1 2.3e-06 27.3 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ49862.1 - 0.00047 20.1 0.1 0.043 13.7 0.1 2.3 2 0 0 2 2 2 1 KR domain DHHA1 PF02272.19 KXZ49862.1 - 0.19 12.1 1.5 0.53 10.7 1.1 1.9 2 0 0 2 2 2 0 DHHA1 domain NTP_transf_2 PF01909.23 KXZ49863.1 - 2.9e-05 24.3 0.0 5.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PBP_sp32 PF07222.12 KXZ49863.1 - 0.18 11.2 0.4 0.28 10.6 0.4 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ank_2 PF12796.7 KXZ49864.1 - 5.7e-14 52.5 0.1 2.3e-05 24.9 0.0 4.3 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49864.1 - 8.8e-12 45.3 3.8 0.27 11.9 0.0 7.1 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49864.1 - 3e-08 33.3 1.0 7.9 7.4 0.0 8.0 9 1 1 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 KXZ49864.1 - 5.3e-08 33.0 5.2 0.48 10.8 0.0 6.0 3 2 3 6 6 6 3 Ankyrin repeats (many copies) YejG PF13989.6 KXZ49864.1 - 0.13 12.7 0.5 0.27 11.7 0.5 1.4 1 0 0 1 1 1 0 YejG-like protein Ank PF00023.30 KXZ49864.1 - 0.14 12.6 0.5 33 5.1 0.2 4.1 4 1 0 4 4 4 0 Ankyrin repeat NTP_transf_2 PF01909.23 KXZ49865.1 - 0.00024 21.3 0.0 0.00043 20.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ank_2 PF12796.7 KXZ49866.1 - 1.6e-10 41.5 0.1 4.7e-05 23.9 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49866.1 - 9.2e-07 29.3 0.5 5.2 7.8 0.0 6.0 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ49866.1 - 0.00083 19.6 0.1 81 4.3 0.0 6.7 8 1 1 9 9 9 0 Ankyrin repeat Ank_5 PF13857.6 KXZ49866.1 - 0.011 16.0 0.2 27 5.2 0.0 4.4 2 2 3 5 5 5 0 Ankyrin repeats (many copies) ATX_III PF08098.11 KXZ49866.1 - 4.1 7.5 6.8 89 3.2 0.5 4.0 3 0 0 3 3 3 0 Anemonia sulcata toxin III family OB_NTP_bind PF07717.16 KXZ49867.1 - 7.5e-17 61.5 0.0 1.4e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXZ49867.1 - 3.1e-15 56.4 3.7 3.2e-15 56.3 0.2 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) RWD PF05773.22 KXZ49867.1 - 2.6e-06 27.7 0.0 0.052 13.8 0.0 2.3 2 0 0 2 2 2 2 RWD domain UBA PF00627.31 KXZ49867.1 - 3.6e-05 23.6 8.1 0.037 13.9 0.2 3.1 3 0 0 3 3 3 2 UBA/TS-N domain zf-Di19 PF05605.12 KXZ49867.1 - 0.0015 18.8 0.3 0.003 17.8 0.3 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXZ49867.1 - 0.0085 16.9 3.1 0.014 16.1 0.3 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXZ49867.1 - 0.013 15.9 0.4 0.013 15.9 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-BED PF02892.15 KXZ49867.1 - 0.054 13.5 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 BED zinc finger zf-CHCC PF10276.9 KXZ49867.1 - 0.7 10.0 3.8 0.42 10.7 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger domain Lactamase_B_2 PF12706.7 KXZ49870.1 - 7.2e-06 25.7 0.0 3.1e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Na_H_antiport_2 PF13726.6 KXZ49870.1 - 0.15 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Na+-H+ antiporter family PHD PF00628.29 KXZ49871.1 - 6.4e-12 45.2 10.5 1.1e-11 44.4 10.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 KXZ49871.1 - 0.0027 18.0 7.1 0.0049 17.2 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-PHD-like PF15446.6 KXZ49871.1 - 0.016 14.8 1.0 0.026 14.1 1.0 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KXZ49871.1 - 0.025 14.1 3.0 0.025 14.1 3.0 2.0 2 1 0 2 2 2 0 PHD-finger C1_2 PF03107.16 KXZ49871.1 - 0.061 13.7 6.6 0.12 12.7 3.2 2.3 2 0 0 2 2 2 0 C1 domain Pex14_N PF04695.13 KXZ49872.1 - 0.071 13.8 0.4 0.16 12.6 0.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TraB PF01963.17 KXZ49872.1 - 0.7 9.7 3.2 36 4.1 0.1 3.5 4 0 0 4 4 4 0 TraB family Oxidored_q6 PF01058.22 KXZ49873.1 - 1e-21 77.1 0.1 2.2e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit mTERF PF02536.14 KXZ49873.1 - 6.7e-09 35.1 0.0 9.5e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 mTERF ThiF PF00899.21 KXZ49874.1 - 5.8e-58 196.1 0.0 7.1e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KXZ49874.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Nucleotid_trans PF03407.16 KXZ49876.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Response_reg PF00072.24 KXZ49877.1 - 8.6e-17 61.3 0.1 1.3e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain DEC-1_N PF04625.13 KXZ49877.1 - 0.021 13.9 5.0 0.025 13.6 5.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SAM_2 PF07647.17 KXZ49877.1 - 0.044 13.9 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Cellulase PF00150.18 KXZ49878.1 - 2.3e-08 33.8 0.0 2.7e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KXZ49878.1 - 0.00078 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 KXZ49878.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain CBM_20 PF00686.19 KXZ49879.1 - 8.6e-29 99.3 0.0 1.7e-13 50.3 0.0 2.6 2 0 0 2 2 2 2 Starch binding domain NYD-SP28_assoc PF14775.6 KXZ49879.1 - 0.16 12.1 3.6 0.81 9.8 0.4 4.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain OTCace PF00185.24 KXZ49880.1 - 1.9e-51 174.3 0.0 2.9e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KXZ49880.1 - 1.2e-46 158.4 0.0 1.9e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain hEGF PF12661.7 KXZ49880.1 - 0.13 13.0 0.7 0.28 11.9 0.7 1.5 1 0 0 1 1 1 0 Human growth factor-like EGF cEGF PF12662.7 KXZ49880.1 - 0.24 11.4 0.9 0.49 10.4 0.9 1.5 1 0 0 1 1 1 0 Complement Clr-like EGF-like WD40 PF00400.32 KXZ49881.1 - 6.6e-30 102.7 16.2 0.0079 17.0 0.0 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ49881.1 - 2.3e-12 47.0 0.1 0.027 14.7 0.0 6.4 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXZ49881.1 - 0.059 12.9 0.0 1 8.9 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain ACBP PF00887.19 KXZ49882.1 - 6.3e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF3254 PF11630.8 KXZ49882.1 - 0.19 12.0 0.1 2.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3254) S1 PF00575.23 KXZ49883.1 - 3.2e-16 59.4 1.6 1.5e-08 34.9 0.5 2.7 2 0 0 2 2 2 2 S1 RNA binding domain PCB_OB PF17092.5 KXZ49883.1 - 2.8e-05 24.8 0.1 0.0042 17.8 0.1 2.3 2 0 0 2 2 2 1 Penicillin-binding protein OB-like domain RNA_pol_Rbc25 PF08292.12 KXZ49883.1 - 0.0017 18.6 0.9 0.13 12.5 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase III subunit Rpc25 Dehydrin PF00257.19 KXZ49883.1 - 0.0084 16.7 9.1 0.0084 16.7 9.1 1.9 2 0 0 2 2 2 1 Dehydrin S1_2 PF13509.6 KXZ49883.1 - 0.042 13.9 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 S1 domain AP3D1 PF06375.11 KXZ49883.1 - 0.94 9.7 12.8 2.1 8.5 12.8 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF755 PF05501.11 KXZ49883.1 - 4.4 7.6 18.0 8.9 6.6 18.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) UPF0564 PF10595.9 KXZ49884.1 - 6.4e-13 48.5 24.0 3.1e-12 46.3 24.0 2.1 1 1 0 1 1 1 1 Uncharacterised protein family UPF0564 HBS1_N PF08938.10 KXZ49887.1 - 0.0059 16.9 2.1 0.014 15.7 2.1 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GCIP PF13324.6 KXZ49887.1 - 0.09 12.4 0.5 0.13 11.8 0.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 KXZ49887.1 - 0.44 10.3 6.3 0.71 9.6 6.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LRR_4 PF12799.7 KXZ49888.1 - 0.063 13.7 0.4 67 4.1 0.0 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ49888.1 - 0.082 13.0 2.7 1.3 9.2 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 KXZ49888.1 - 0.38 10.6 2.5 3.8 7.4 0.1 3.5 4 0 0 4 4 4 0 Leucine rich repeat Cullin_binding PF03556.15 KXZ49891.1 - 1e-24 87.3 0.0 1.6e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Cullin binding RPE65 PF03055.15 KXZ49892.1 - 4.6e-98 329.4 0.0 7.4e-98 328.7 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AAA_lid_3 PF17862.1 KXZ49894.1 - 3.2e-11 42.8 0.0 6.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KXZ49894.1 - 1.5e-08 35.1 0.1 6e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DnaJ PF00226.31 KXZ49895.1 - 3.9e-05 23.7 0.4 7.4e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_32N PF00251.20 KXZ49898.1 - 1.1e-39 136.9 0.0 7e-39 134.2 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXZ49898.1 - 3.7e-05 23.8 0.0 6.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KXZ49899.1 - 6.2e-22 78.5 0.0 1.3e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXZ49899.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal HrcA_DNA-bdg PF03444.15 KXZ49900.1 - 0.0087 15.7 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Focal_AT PF03623.13 KXZ49901.1 - 0.0067 16.4 1.2 0.0067 16.4 1.2 1.9 2 0 0 2 2 2 1 Focal adhesion targeting region SH2 PF00017.24 KXZ49902.1 - 0.028 14.5 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 SH2 domain TFIIA PF03153.13 KXZ49902.1 - 3.4 7.6 8.4 5.8 6.8 8.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L31e PF01198.19 KXZ49903.1 - 3.1e-40 136.3 2.4 3.8e-40 136.0 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CTP_transf_1 PF01148.20 KXZ49904.1 - 4.4e-61 207.0 15.6 6.4e-61 206.4 15.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Adaptin_N PF01602.20 KXZ49905.1 - 2.1e-87 293.9 0.0 4.7e-87 292.7 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KXZ49905.1 - 8.2e-11 42.2 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain PSI_PsaF PF02507.15 KXZ49906.1 - 1e-78 263.1 0.1 1.3e-78 262.7 0.1 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit III Arf PF00025.21 KXZ49908.1 - 2.9e-66 222.2 0.0 3.3e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXZ49908.1 - 1.2e-13 51.3 0.0 1.7e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXZ49908.1 - 8.4e-12 44.9 0.0 9e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXZ49908.1 - 1.3e-11 44.3 0.2 1.6e-09 37.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXZ49908.1 - 3.4e-11 43.0 0.0 3.6e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXZ49908.1 - 4e-10 39.4 0.0 5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXZ49908.1 - 0.00042 20.4 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXZ49908.1 - 0.015 14.6 0.1 0.031 13.6 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.27 KXZ49908.1 - 0.17 11.4 0.1 0.56 9.7 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXZ49908.1 - 0.18 12.3 0.0 0.76 10.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter RasGAP_C PF03836.15 KXZ49909.1 - 0.009 16.2 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 RasGAP C-terminus DUF4349 PF14257.6 KXZ49909.1 - 0.049 13.1 3.3 0.13 11.7 3.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2098 PF09871.9 KXZ49909.1 - 0.077 13.3 0.8 0.18 12.1 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Fungal_TACC PF12709.7 KXZ49909.1 - 0.24 11.9 4.1 0.16 12.4 2.1 1.7 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TolA_bind_tri PF16331.5 KXZ49909.1 - 4.4 7.4 11.2 1.6 8.9 7.5 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation DNA_pol_phi PF04931.13 KXZ49909.1 - 5.6 4.9 7.8 1.2 7.2 3.7 1.7 2 0 0 2 2 2 0 DNA polymerase phi SNCAIP_SNCA_bd PF16700.5 KXZ49909.1 - 9.7 6.0 7.0 3 7.6 2.7 2.2 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Lactamase_B_6 PF16661.5 KXZ49912.1 - 1.2e-34 119.5 0.0 2.4e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KXZ49912.1 - 1.2e-13 51.3 0.0 2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain CPSF100_C PF13299.6 KXZ49912.1 - 1.2e-08 35.3 0.0 7.9e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 KXZ49912.1 - 5.2e-06 26.3 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KXZ49912.1 - 0.012 15.6 0.5 0.057 13.4 0.0 2.4 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXZ49912.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SHIPPO-rpt PF07004.12 KXZ49913.1 - 0.099 13.6 12.3 3.5 8.7 0.0 4.5 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat DUF3484 PF11983.8 KXZ49914.1 - 7.8 7.7 8.7 5.9 8.1 6.8 1.7 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch BRE1 PF08647.11 KXZ49915.1 - 0.05 13.7 1.0 0.05 13.7 1.0 4.7 4 1 0 4 4 4 0 BRE1 E3 ubiquitin ligase Shugoshin_N PF07558.11 KXZ49915.1 - 0.051 13.5 0.5 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region BBP1_C PF15272.6 KXZ49915.1 - 0.48 10.2 11.0 0.31 10.9 6.4 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal RRM_1 PF00076.22 KXZ49916.1 - 2.5e-19 68.9 0.0 3.2e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ49916.1 - 0.18 11.9 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif Dus PF01207.17 KXZ49917.1 - 2.8e-71 240.2 0.0 3.6e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 KXZ49917.1 - 1.9e-05 24.5 0.9 0.0018 18.1 0.1 2.2 1 1 1 2 2 2 2 SOR/SNZ family FA_hydroxylase PF04116.13 KXZ49918.1 - 7.8e-24 84.5 15.2 1.3e-23 83.9 13.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily tRNA-synt_1g PF09334.11 KXZ49919.1 - 1.2e-67 228.4 0.0 1.9e-44 152.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXZ49919.1 - 1.2e-17 63.5 0.1 1.1e-08 33.9 0.0 2.6 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KXZ49919.1 - 1e-07 31.6 0.4 0.01 15.2 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KXZ49919.1 - 1.2e-07 31.8 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA RNA_pol_Rpc4 PF05132.14 KXZ49919.1 - 0.15 12.5 3.8 0.25 11.8 3.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 His_Phos_1 PF00300.22 KXZ49920.1 - 4.1e-15 56.0 0.1 6.6e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TMEM208_SND2 PF05620.11 KXZ49921.1 - 0.033 14.0 0.9 0.04 13.7 0.1 1.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 WD40 PF00400.32 KXZ49922.1 - 1.5e-39 133.3 21.1 7.1e-09 36.2 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ49922.1 - 3e-14 53.1 0.0 0.08 13.3 0.0 5.6 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ49922.1 - 2e-05 23.7 0.0 0.26 10.2 0.0 3.4 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXZ49922.1 - 3.8e-05 22.5 0.0 0.0055 15.4 0.0 3.4 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXZ49922.1 - 0.034 13.5 0.3 2.5 7.3 0.0 3.3 4 1 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KXZ49922.1 - 2.2 8.9 7.0 53 4.5 0.0 5.1 5 1 0 5 5 5 0 PQQ-like domain DUF1084 PF06454.11 KXZ49923.1 - 3.6e-118 393.9 0.7 4.1e-118 393.7 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) MIG-14_Wnt-bd PF06664.12 KXZ49923.1 - 2.1e-06 27.2 6.0 2.8e-06 26.8 6.0 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF4153 PF13687.6 KXZ49923.1 - 0.0007 19.3 1.5 0.0007 19.3 1.5 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4153) DUF3784 PF12650.7 KXZ49923.1 - 1.5 9.1 4.6 0.28 11.4 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) FixQ PF05545.11 KXZ49923.1 - 2 8.5 5.9 5.7 7.0 0.1 3.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ CEP19 PF14933.6 KXZ49924.1 - 1.2e-19 71.3 1.0 1.7e-19 70.7 1.0 1.2 1 0 0 1 1 1 1 CEP19-like protein Cullin_binding PF03556.15 KXZ49925.1 - 2e-35 121.8 1.5 2.9e-35 121.3 1.5 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KXZ49925.1 - 3.4e-11 42.8 0.0 7.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Aida_C2 PF14186.6 KXZ49926.1 - 7.1e-45 152.2 0.0 1e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 KXZ49926.1 - 1.3e-24 86.6 0.0 2.7e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Aida N-terminus DOCK-C2 PF14429.6 KXZ49926.1 - 0.0044 16.9 0.5 0.0078 16.0 0.5 1.4 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins MIT PF04212.18 KXZ49926.1 - 0.008 16.2 0.3 0.03 14.4 0.3 2.1 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain Staygreen PF12638.7 KXZ49927.1 - 3.6e-32 111.2 0.0 5.2e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Staygreen protein eIF3_subunit PF08597.10 KXZ49927.1 - 0.77 9.6 9.1 1.3 8.9 9.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peptidase_S30 PF01577.16 KXZ49927.1 - 4.6 6.8 8.1 8.6 5.9 8.1 1.4 1 1 0 1 1 1 0 Potyvirus P1 protease Mito_carr PF00153.27 KXZ49928.1 - 3.6e-43 145.4 2.5 1.1e-18 66.9 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_6 PF13516.6 KXZ49929.1 - 5.3e-08 32.3 0.3 2.4e-05 24.0 0.2 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KXZ49929.1 - 0.026 15.0 1.3 0.09 13.2 0.6 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ49929.1 - 0.074 13.6 0.1 29 5.7 0.0 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 KXZ49929.1 - 0.12 12.1 0.4 2.8 7.8 0.3 2.6 1 1 0 1 1 1 0 Leucine rich repeat PQ-loop PF04193.14 KXZ49930.1 - 7.2e-07 28.9 0.2 7.7e-06 25.6 0.0 2.8 2 0 0 2 2 2 1 PQ loop repeat Usp PF00582.26 KXZ49931.1 - 0.00069 20.1 1.0 0.00069 20.1 1.0 2.5 2 1 0 2 2 2 1 Universal stress protein family 2OG-FeII_Oxy_3 PF13640.6 KXZ49933.1 - 4.2e-13 50.0 0.0 5.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KXZ49933.1 - 0.0011 19.5 0.0 0.0016 19.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PsaL PF02605.15 KXZ49934.1 - 3.6e-55 185.7 0.6 4.4e-55 185.5 0.6 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI Pkinase PF00069.25 KXZ49935.1 - 1.5e-55 188.4 0.0 1.8e-48 165.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49935.1 - 2.5e-32 112.2 0.0 3.8e-30 105.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase cNMP_binding PF00027.29 KXZ49935.1 - 3.2e-11 43.2 0.0 0.00015 21.8 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KXZ49935.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ49935.1 - 0.066 13.1 0.0 0.67 9.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 KXZ49936.1 - 3.4e-52 177.2 0.0 4.6e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phage_tail_APC PF16778.5 KXZ49936.1 - 0.084 12.8 0.7 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Arf PF00025.21 KXZ49937.1 - 1.4e-80 268.9 0.1 1.6e-80 268.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXZ49937.1 - 4.1e-14 52.8 0.0 5.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXZ49937.1 - 2.3e-13 50.0 0.0 2.8e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXZ49937.1 - 4.3e-13 49.2 0.0 4.8e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXZ49937.1 - 1.1e-12 47.8 1.1 1.8e-08 34.0 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXZ49937.1 - 1.1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXZ49937.1 - 2e-05 24.6 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXZ49937.1 - 0.0051 16.1 0.3 0.016 14.5 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase TPP_enzyme_N PF02776.18 KXZ49938.1 - 3e-55 186.5 0.2 2e-52 177.3 0.1 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXZ49938.1 - 4.2e-46 156.1 0.2 8.5e-46 155.1 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXZ49938.1 - 4.3e-45 153.2 0.0 5.9e-43 146.3 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ank_2 PF12796.7 KXZ49940.1 - 7.4e-67 221.9 20.2 1.1e-16 61.2 1.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ49940.1 - 1.5e-50 169.0 16.3 3.4e-10 40.2 0.1 7.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49940.1 - 8.9e-50 165.1 28.4 2.5e-06 27.7 0.2 10.9 11 0 0 11 11 10 8 Ankyrin repeat Ank_3 PF13606.6 KXZ49940.1 - 9.7e-50 160.8 7.3 2.4e-05 24.4 0.0 10.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KXZ49940.1 - 3.6e-43 145.1 19.9 3.6e-09 36.7 0.1 8.6 3 2 6 9 9 8 8 Ankyrin repeats (many copies) Roc PF08477.13 KXZ49940.1 - 1.4e-38 131.8 0.0 7.5e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXZ49940.1 - 1.4e-21 76.8 0.0 1.8e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Arf PF00025.21 KXZ49940.1 - 7e-16 58.2 0.0 1.3e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family COR PF16095.5 KXZ49940.1 - 1.4e-11 44.6 0.0 2.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Gtr1_RagA PF04670.12 KXZ49940.1 - 5.6e-09 35.7 0.0 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KXZ49940.1 - 1.9e-08 34.9 0.0 0.0053 17.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_33 PF13671.6 KXZ49940.1 - 6.4e-08 32.9 0.0 0.023 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXZ49940.1 - 2.7e-07 30.9 0.0 0.042 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXZ49940.1 - 3.4e-07 30.8 0.0 0.052 13.9 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain Mg_chelatase PF01078.21 KXZ49940.1 - 4.9e-07 29.3 0.0 0.0073 15.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXZ49940.1 - 3.3e-06 27.4 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KXZ49940.1 - 8.1e-06 25.8 0.0 0.097 12.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXZ49940.1 - 1.2e-05 25.3 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 KXZ49940.1 - 2e-05 23.9 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain AAA PF00004.29 KXZ49940.1 - 2.6e-05 24.6 0.0 0.39 11.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KXZ49940.1 - 2.8e-05 23.8 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KXZ49940.1 - 2.9e-05 23.9 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 KXZ49940.1 - 3.4e-05 23.6 0.0 0.35 10.6 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KXZ49940.1 - 4.7e-05 23.4 0.1 0.5 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXZ49940.1 - 4.8e-05 23.9 0.0 0.61 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXZ49940.1 - 6e-05 22.7 0.1 0.42 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXZ49940.1 - 8.1e-05 22.6 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXZ49940.1 - 9.2e-05 22.5 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.6 KXZ49940.1 - 0.00014 22.0 0.0 1.7 8.8 0.0 3.6 3 1 2 5 5 3 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXZ49940.1 - 0.00014 21.6 0.0 0.5 10.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KXZ49940.1 - 0.00022 21.3 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXZ49940.1 - 0.00022 20.8 0.0 0.81 9.2 0.0 2.5 3 0 0 3 3 2 2 P-loop containing dynein motor region SRPRB PF09439.10 KXZ49940.1 - 0.0009 18.7 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit RuvB_N PF05496.12 KXZ49940.1 - 0.0011 18.8 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KXZ49940.1 - 0.0012 18.6 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXZ49940.1 - 0.002 18.1 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 KXZ49940.1 - 0.0022 16.9 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein AAA_29 PF13555.6 KXZ49940.1 - 0.0023 17.6 0.1 2.3 8.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 KXZ49940.1 - 0.0025 17.5 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 KXZ49940.1 - 0.0028 17.4 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 KXZ49940.1 - 0.0061 15.6 0.0 3 6.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein TniB PF05621.11 KXZ49940.1 - 0.0075 15.7 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Zeta_toxin PF06414.12 KXZ49940.1 - 0.0079 15.5 0.1 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KXZ49940.1 - 0.014 15.7 0.0 10 6.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 KXZ49940.1 - 0.023 14.5 0.0 8.2 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Guanylate_kin PF00625.21 KXZ49940.1 - 0.024 14.3 0.0 8.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase NTPase_1 PF03266.15 KXZ49940.1 - 0.034 14.1 0.1 11 5.8 0.0 2.3 2 0 0 2 2 2 0 NTPase MobB PF03205.14 KXZ49940.1 - 0.037 13.9 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Cytidylate_kin PF02224.18 KXZ49940.1 - 0.037 13.7 0.0 59 3.3 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase AAA_17 PF13207.6 KXZ49940.1 - 0.081 13.3 0.0 23 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KXZ49940.1 - 0.086 12.6 0.0 16 5.2 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_32 PF13654.6 KXZ49940.1 - 0.15 10.8 0.0 11 4.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXZ49940.1 - 0.16 12.5 0.0 30 5.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KXZ49940.1 - 0.17 11.1 0.0 19 4.4 0.0 2.1 2 0 0 2 2 2 0 Septin NAP PF00956.18 KXZ49941.1 - 3e-59 200.4 0.0 2.3e-34 118.8 0.0 4.0 2 2 0 2 2 2 2 Nucleosome assembly protein (NAP) Herpes_UL56 PF04534.12 KXZ49941.1 - 0.0084 15.6 4.1 0.035 13.6 4.1 2.1 1 0 0 1 1 1 1 Herpesvirus UL56 protein RNA_pol_3_Rpc31 PF11705.8 KXZ49941.1 - 0.018 15.3 2.7 0.018 15.3 2.7 3.2 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 KXZ49941.1 - 0.097 12.0 21.6 0.36 10.1 8.0 2.5 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 KXZ49941.1 - 2.3 7.5 24.2 3.2 7.1 6.8 2.4 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 KXZ49941.1 - 2.7 6.1 24.4 1.9 6.6 8.3 2.1 2 0 0 2 2 2 0 Nop14-like family Mpp10 PF04006.12 KXZ49941.1 - 4.9 5.5 22.0 4.2 5.7 6.2 2.2 2 0 0 2 2 2 0 Mpp10 protein Pkinase_Tyr PF07714.17 KXZ49942.1 - 4.2e-36 124.5 0.0 6.2e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49942.1 - 1.1e-28 100.4 0.0 4e-17 62.4 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ49942.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Wzy_C PF04932.15 KXZ49942.1 - 0.15 11.7 4.2 0.29 10.7 4.2 1.4 1 0 0 1 1 1 0 O-Antigen ligase DUF2207 PF09972.9 KXZ49942.1 - 4.8 5.8 14.1 7.5 5.2 14.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HAD PF12710.7 KXZ49943.1 - 0.0071 16.8 4.4 0.57 10.5 0.3 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Kelch_3 PF13415.6 KXZ49944.1 - 1.1e-33 114.8 5.0 2.5e-08 34.0 0.2 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KXZ49944.1 - 2.7e-33 113.7 5.8 5.6e-06 26.3 0.0 6.8 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ49944.1 - 3.6e-30 103.2 2.6 1.5e-05 25.1 0.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KXZ49944.1 - 4.7e-26 90.3 3.0 1.3e-05 25.1 0.0 7.4 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 KXZ49944.1 - 3.8e-20 71.0 7.9 0.0028 17.6 0.0 6.2 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 KXZ49944.1 - 7.6e-17 60.6 12.7 2.7e-05 23.6 0.1 7.0 6 1 0 6 6 6 4 Kelch motif IQ PF00612.27 KXZ49944.1 - 8.7e-06 25.1 2.3 1.6e-05 24.3 2.3 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Methyltransf_20 PF12147.8 KXZ49945.1 - 0.24 10.5 0.6 0.56 9.3 0.2 1.7 2 0 0 2 2 2 0 Putative methyltransferase FMO-like PF00743.19 KXZ49946.1 - 4.4e-07 28.7 0.0 0.0045 15.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXZ49946.1 - 0.0055 15.9 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) P21-Arc PF04062.14 KXZ49947.1 - 4.9e-47 160.2 0.0 5.8e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CLPTM1 PF05602.12 KXZ49948.1 - 7.6e-131 437.1 0.0 9.1e-131 436.8 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KXZ49948.1 - 3.7e-06 26.6 0.8 0.02 14.7 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat TMEM208_SND2 PF05620.11 KXZ49948.1 - 0.022 14.5 2.4 0.32 10.7 0.2 2.8 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Pkinase PF00069.25 KXZ49949.1 - 4.9e-37 127.7 0.0 2.9e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49949.1 - 5.3e-37 127.5 0.0 3.5e-29 101.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49949.1 - 1.6e-10 40.3 0.0 2.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SKG6 PF08693.10 KXZ49949.1 - 0.0015 17.9 7.7 0.0015 17.9 7.7 2.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Kinase-like PF14531.6 KXZ49949.1 - 0.0026 17.1 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ49949.1 - 0.044 13.7 0.0 0.044 13.7 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family FMO-like PF00743.19 KXZ49951.1 - 0.017 13.6 0.0 0.02 13.3 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like DUF5086 PF16985.5 KXZ49951.1 - 0.058 13.3 0.1 0.46 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5086) Ank_2 PF12796.7 KXZ49952.1 - 1.2e-09 38.7 1.0 1e-06 29.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ49952.1 - 8.7e-08 31.9 2.3 0.046 14.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXZ49952.1 - 2.6e-07 31.0 0.1 0.002 18.7 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ49952.1 - 1.2e-05 25.5 8.8 0.026 15.0 0.1 4.9 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXZ49952.1 - 4.3e-05 23.7 2.2 0.033 14.5 0.0 3.6 1 1 2 3 3 3 1 Ankyrin repeats (many copies) adh_short PF00106.25 KXZ49953.1 - 1.5e-15 57.2 0.0 4e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ49953.1 - 5.5e-14 52.3 0.0 4.9e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase LON_substr_bdg PF02190.16 KXZ49954.1 - 8.1e-08 32.4 0.0 5.3e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Helicase_C_2 PF13307.6 KXZ49955.1 - 7.8e-52 175.9 0.0 1.3e-51 175.2 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXZ49955.1 - 6.9e-30 104.0 0.2 2e-24 86.2 0.0 2.2 1 1 1 2 2 2 2 DEAD_2 DEAD PF00270.29 KXZ49955.1 - 2.3e-06 27.5 0.0 4.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ49955.1 - 0.012 15.7 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HBB PF06777.11 KXZ49955.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Helical and beta-bridge domain SNF2_N PF00176.23 KXZ49955.1 - 0.04 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_19 PF13245.6 KXZ49955.1 - 0.06 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ49955.1 - 0.1 12.9 0.0 18 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain FA_desaturase PF00487.24 KXZ49956.1 - 1.4e-19 71.0 28.3 2.2e-19 70.3 28.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase ubiquitin PF00240.23 KXZ49957.1 - 7.6e-21 73.6 0.0 9.8e-21 73.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Prok-RING_4 PF14447.6 KXZ49957.1 - 7.8e-09 35.3 8.0 7.8e-09 35.3 8.0 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rad60-SLD PF11976.8 KXZ49957.1 - 3.4e-08 33.2 0.1 4.2e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RING_2 PF13639.6 KXZ49957.1 - 6.4e-07 29.6 14.4 6.5e-07 29.6 10.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXZ49957.1 - 7.3e-07 29.0 9.6 7.3e-07 29.0 9.6 2.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXZ49957.1 - 3e-06 27.0 11.3 3e-06 27.0 11.3 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ49957.1 - 6.4e-06 26.1 11.5 6.1e-05 23.0 11.5 2.3 1 1 0 1 1 1 1 RING-type zinc-finger DUF2407 PF10302.9 KXZ49957.1 - 0.0001 22.8 0.1 0.00015 22.3 0.1 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain zf-C3HC4 PF00097.25 KXZ49957.1 - 0.0003 20.6 6.8 0.0003 20.6 6.8 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ49957.1 - 0.00055 19.7 10.2 0.00055 19.7 10.2 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ubiquitin_2 PF14560.6 KXZ49957.1 - 0.00086 19.7 0.0 0.0021 18.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXZ49957.1 - 0.0045 16.9 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain zf-C3HC4_4 PF15227.6 KXZ49957.1 - 0.035 14.3 10.5 0.18 12.0 7.9 2.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Ubiquitin_4 PF18036.1 KXZ49957.1 - 0.11 12.5 0.2 9.5 6.4 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXZ49957.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like zf-RING_10 PF16685.5 KXZ49957.1 - 0.18 11.9 7.7 0.37 10.9 7.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXZ49957.1 - 0.46 10.3 11.3 0.25 11.1 8.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 KXZ49957.1 - 3.9 7.7 11.7 18 5.6 11.7 2.2 1 1 0 1 1 1 0 FYVE zinc finger SET PF00856.28 KXZ49958.1 - 0.00014 22.3 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 SET domain Cpn60_TCP1 PF00118.24 KXZ49961.1 - 1.2e-33 116.6 0.1 1.5e-33 116.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2264 PF10022.9 KXZ49961.1 - 0.11 11.5 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Peptidase_S64 PF08192.11 KXZ49961.1 - 0.15 10.5 0.0 0.17 10.3 0.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_C1 PF00112.23 KXZ49962.1 - 3.2e-18 66.6 0.0 5.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease EccE PF11203.8 KXZ49962.1 - 9.2e-05 22.7 0.8 0.0022 18.3 0.2 2.4 2 0 0 2 2 2 1 Putative type VII ESX secretion system translocon, EccE Cpn60_TCP1 PF00118.24 KXZ49964.1 - 3.9e-160 533.7 0.0 4.8e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family A_thal_3526 PF09713.10 KXZ49965.1 - 2.1e-24 85.5 1.0 3e-24 85.0 1.0 1.2 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) Snapin_Pallidin PF14712.6 KXZ49966.1 - 0.17 12.4 0.8 0.82 10.1 0.8 2.0 2 0 0 2 2 2 0 Snapin/Pallidin MFS_1 PF07690.16 KXZ49968.1 - 6.6e-45 153.6 31.4 6.6e-45 153.6 31.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXZ49968.1 - 0.00031 20.2 10.5 0.00031 20.2 10.5 3.1 2 1 1 3 3 3 3 Uncharacterised MFS-type transporter YbfB ABC2_membrane PF01061.24 KXZ49969.1 - 6.8e-75 251.1 56.1 2.8e-40 138.0 23.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXZ49969.1 - 1.1e-26 94.0 0.0 1.8e-14 54.4 0.0 2.8 2 1 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 KXZ49969.1 - 6e-07 29.1 0.0 6e-07 29.1 0.0 2.5 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_29 PF13555.6 KXZ49969.1 - 1.2e-06 28.2 1.2 0.045 13.5 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KXZ49969.1 - 2.4e-06 27.2 6.8 0.0061 16.1 0.2 3.4 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KXZ49969.1 - 9.1e-06 25.7 0.0 0.046 13.5 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXZ49969.1 - 1.2e-05 25.7 0.2 0.059 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC_trans_N PF14510.6 KXZ49969.1 - 0.00023 21.7 0.0 0.00053 20.5 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA PF00004.29 KXZ49969.1 - 0.00037 20.9 0.6 0.27 11.7 0.1 3.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ49969.1 - 0.00042 20.6 1.1 0.65 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KXZ49969.1 - 0.00062 19.7 1.7 0.15 12.0 0.5 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KXZ49969.1 - 0.00068 18.9 9.8 0.00068 18.9 9.8 3.2 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_28 PF13521.6 KXZ49969.1 - 0.00099 19.4 1.1 1.8 8.8 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXZ49969.1 - 0.0025 18.3 0.5 1.7 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXZ49969.1 - 0.0043 16.8 3.6 2.4 7.8 0.1 3.4 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KXZ49969.1 - 0.0052 16.3 0.0 8.6 5.7 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXZ49969.1 - 0.0053 17.3 0.1 1.4 9.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXZ49969.1 - 0.011 15.8 0.6 3 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXZ49969.1 - 0.016 14.9 0.4 5 6.9 0.3 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KXZ49969.1 - 0.043 14.0 1.4 5.6 7.1 0.2 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXZ49969.1 - 0.055 12.9 2.3 0.59 9.5 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 KXZ49969.1 - 0.067 12.8 2.1 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXZ49969.1 - 0.089 12.7 1.3 11 6.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 KXZ49969.1 - 0.11 12.7 1.1 2.3 8.5 0.0 3.2 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 KXZ49969.1 - 0.11 12.4 0.2 1.8 8.5 0.1 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 KXZ49969.1 - 0.14 12.1 2.8 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KXZ49969.1 - 0.15 12.0 0.4 26 4.8 0.3 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DLIC PF05783.11 KXZ49969.1 - 0.2 10.5 1.3 8.6 5.1 0.5 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) RuvB_N PF05496.12 KXZ49969.1 - 0.25 11.1 0.6 9.1 6.0 0.0 2.6 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF3123 PF11321.8 KXZ49969.1 - 1.1 10.0 3.6 2.8 8.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DUF866 PF05907.13 KXZ49970.1 - 5.4e-54 182.3 1.4 1.1e-41 142.3 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) Fip1 PF05182.13 KXZ49970.1 - 0.00014 21.3 0.7 0.51 9.9 0.1 2.4 2 0 0 2 2 2 2 Fip1 motif DUF5017 PF16409.5 KXZ49970.1 - 0.004 16.6 0.7 1.7 8.1 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5017) PriCT_2 PF08707.11 KXZ49970.1 - 0.017 15.5 0.5 7 7.1 0.1 2.3 1 1 1 2 2 2 0 Primase C terminal 2 (PriCT-2) Phe_ZIP PF08916.11 KXZ49970.1 - 0.034 14.8 1.3 13 6.6 0.1 2.7 2 0 0 2 2 2 0 Phenylalanine zipper DUF282 PF03380.14 KXZ49970.1 - 0.12 12.3 3.5 7.3 6.6 0.0 3.4 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF282 AIM24 PF01987.17 KXZ49971.1 - 1.2e-48 165.6 0.1 1.3e-48 165.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 p450 PF00067.22 KXZ49972.1 - 2e-56 191.7 0.0 9.8e-54 182.8 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 SpecificRecomb PF10136.9 KXZ49972.1 - 3.2 5.9 6.8 5.1 5.3 6.8 1.2 1 0 0 1 1 1 0 Site-specific recombinase Peptidase_C1 PF00112.23 KXZ49973.1 - 1e-27 97.7 5.2 1.9e-27 96.8 5.2 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KXZ49973.1 - 0.077 11.8 0.8 0.19 10.4 0.3 1.7 2 0 0 2 2 2 0 Peptidase C1-like family zf-NADH-PPase PF09297.11 KXZ49974.1 - 2e-10 40.2 1.2 4.1e-10 39.1 1.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX PF00293.28 KXZ49974.1 - 3.1e-07 30.5 0.2 1.1e-06 28.7 0.2 1.9 1 1 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KXZ49974.1 - 1.1e-06 29.2 0.1 3.5e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain UPF0020 PF01170.18 KXZ49974.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 zinc_ribbon_2 PF13240.6 KXZ49974.1 - 0.22 11.3 0.9 0.43 10.4 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain UPF0047 PF01894.17 KXZ49975.1 - 9.1e-30 103.2 0.0 1.3e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Amino_oxidase PF01593.24 KXZ49977.1 - 1e-72 245.9 0.1 5.2e-46 157.9 0.1 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ49977.1 - 1.3e-09 38.1 0.1 3.7e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXZ49977.1 - 0.00015 21.1 1.1 0.00024 20.5 0.7 1.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KXZ49977.1 - 0.00067 18.8 0.4 0.0013 17.9 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXZ49977.1 - 0.00067 19.1 0.3 0.0012 18.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXZ49977.1 - 0.0043 16.7 0.2 0.0076 15.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXZ49977.1 - 0.015 14.5 0.4 0.026 13.8 0.4 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KXZ49977.1 - 0.023 13.9 0.5 0.04 13.2 0.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ49977.1 - 0.21 10.3 0.4 0.29 9.8 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein Mito_carr PF00153.27 KXZ49978.1 - 1.2e-43 147.0 5.5 1.5e-16 60.1 0.3 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein His_Phos_2 PF00328.22 KXZ49979.1 - 6.4e-12 45.5 0.0 0.00017 21.0 0.0 3.3 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) ubiquitin PF00240.23 KXZ49980.1 - 2.4e-81 267.5 11.7 2.9e-34 116.6 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 KXZ49980.1 - 2e-39 133.2 10.3 2.6e-16 59.2 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXZ49980.1 - 3e-16 59.6 4.3 0.00016 22.1 0.1 4.2 3 2 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 KXZ49980.1 - 1.8e-09 37.4 0.9 0.017 15.1 0.1 3.2 3 0 0 3 3 3 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXZ49980.1 - 5.4e-08 32.9 1.2 0.062 13.4 0.0 3.7 3 2 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXZ49980.1 - 1.6e-07 31.6 1.6 0.022 15.1 0.1 2.6 1 1 1 3 3 3 2 Ubiquitin-like domain DUF2407 PF10302.9 KXZ49980.1 - 1.2e-06 29.0 0.2 0.051 14.1 0.1 2.4 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXZ49980.1 - 1.8e-05 24.7 13.2 5.7 7.1 0.2 5.0 5 0 0 5 5 5 2 Ubiquitin-like domain DUF3861 PF12977.7 KXZ49980.1 - 0.00015 21.9 0.7 4 7.7 0.0 3.3 3 0 0 3 3 3 2 Domain of Unknown Function with PDB structure (DUF3861) Sde2_N_Ubi PF13019.6 KXZ49980.1 - 0.00045 20.1 0.1 1.1 9.1 0.0 2.2 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KXZ49980.1 - 0.001 18.4 1.1 0.35 10.2 0.0 2.3 3 0 0 3 3 3 2 RNA methyltransferase PDGLE PF13190.6 KXZ49980.1 - 0.026 14.4 0.9 8.1 6.4 0.1 2.7 1 1 1 2 2 2 0 PDGLE domain ACT_5 PF13710.6 KXZ49980.1 - 0.032 14.1 2.0 7.6 6.5 0.0 2.8 3 0 0 3 3 3 0 ACT domain ProRS-C_2 PF09181.10 KXZ49980.1 - 0.041 14.0 2.0 30 4.8 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal UDP-g_GGTase PF06427.11 KXZ49980.1 - 0.048 13.8 1.3 2.1 8.5 0.0 2.9 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 KXZ49980.1 - 0.06 14.1 0.0 22 5.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig domain DUF2870 PF11069.8 KXZ49980.1 - 0.063 13.7 0.0 26 5.3 0.0 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2870) ACT_4 PF13291.6 KXZ49980.1 - 0.096 13.3 0.3 30 5.3 0.0 2.7 3 0 0 3 3 2 0 ACT domain Raf1_HTH PF18579.1 KXZ49980.1 - 0.1 12.3 0.2 71 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain Phage_sheath_1N PF17481.2 KXZ49980.1 - 0.11 13.0 2.8 31 5.1 2.8 3.0 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Tash_PEST PF07708.11 KXZ49980.1 - 0.25 11.5 9.6 3.7 7.8 1.5 2.5 2 0 0 2 2 2 0 Tash protein PEST motif Plexin_cytopl PF08337.12 KXZ49980.1 - 0.33 9.6 5.5 10 4.6 0.4 3.5 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 KXZ49980.1 - 1.3 8.8 4.4 47 3.8 0.1 3.1 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain MIF PF01187.18 KXZ49981.1 - 4.7e-34 117.1 0.0 5.2e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 KXZ49981.1 - 0.00052 19.9 0.0 0.37 10.8 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme LapA_dom PF06305.11 KXZ49983.1 - 0.0098 15.7 0.1 0.0098 15.7 0.1 2.7 3 0 0 3 3 3 1 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 KXZ49983.1 - 4.1 6.9 12.5 0.055 12.9 0.7 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF3707 PF12499.8 KXZ49986.1 - 1.9e-12 47.9 2.9 2.4e-12 47.6 2.9 1.1 1 0 0 1 1 1 1 Pherophorin MFS_1 PF07690.16 KXZ49988.1 - 2.7e-19 69.3 36.5 4.2e-19 68.7 36.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXZ49988.1 - 0.061 12.6 25.6 0.017 14.4 5.2 2.1 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Ribosomal_S20p PF01649.18 KXZ49989.1 - 8e-20 71.3 3.0 1.2e-19 70.7 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S20 DUF1103 PF06513.11 KXZ49989.1 - 0.011 15.4 2.9 0.014 15.0 2.9 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) AROS PF15684.5 KXZ49989.1 - 0.045 14.3 1.1 0.072 13.7 1.1 1.3 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 AOX PF01786.17 KXZ49990.1 - 1.4e-91 305.9 0.7 1.7e-91 305.6 0.7 1.1 1 0 0 1 1 1 1 Alternative oxidase HEAT PF02985.22 KXZ49991.1 - 1e-07 31.6 33.7 0.035 14.4 0.3 10.5 10 0 0 10 10 10 5 HEAT repeat Cnd1 PF12717.7 KXZ49991.1 - 2.8e-05 24.2 0.1 3.3 7.7 0.0 4.2 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXZ49991.1 - 0.07 13.5 44.0 0.085 13.3 2.3 7.5 4 2 3 7 7 7 0 HEAT repeats Coprogen_oxidas PF01218.18 KXZ49992.1 - 1.6e-132 440.8 0.1 1.8e-132 440.6 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase AvrB_AvrC PF05394.11 KXZ49992.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Avirulence protein Pkinase PF00069.25 KXZ49993.1 - 1.3e-26 93.5 0.0 4.5e-11 42.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49993.1 - 3.7e-24 85.4 0.0 6.1e-10 38.8 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49993.1 - 0.014 14.2 0.0 0.083 11.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KXZ49993.1 - 0.24 11.0 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Peptidase_C1 PF00112.23 KXZ49994.1 - 2.2e-07 31.2 0.2 1.2e-06 28.8 0.2 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Pkinase PF00069.25 KXZ49995.1 - 2e-26 93.0 0.0 1.1e-11 44.6 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49995.1 - 3.8e-25 88.6 0.0 3.5e-10 39.6 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49995.1 - 0.0019 17.1 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49995.1 - 0.053 13.4 4.4 1.8 8.4 0.0 3.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ49996.1 - 1.4e-23 83.5 0.0 1.8e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ49996.1 - 4.3e-22 78.7 0.0 2.3e-13 50.1 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ49996.1 - 0.001 18.0 0.0 0.0044 15.9 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ49996.1 - 0.0017 18.3 6.5 0.055 13.4 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ49997.1 - 6.9e-28 97.7 0.0 4.3e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ49997.1 - 1.3e-26 93.4 0.0 6.3e-10 38.8 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ49997.1 - 0.0012 17.7 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Herpes_gE PF02480.16 KXZ49997.1 - 0.055 12.2 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CcmD PF04995.14 KXZ49997.1 - 0.51 10.5 6.2 0.07 13.2 0.7 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) APH PF01636.23 KXZ49997.1 - 0.82 9.5 9.7 0.35 10.8 0.1 2.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-MYND PF01753.18 KXZ49998.1 - 7.2e-06 26.0 8.8 7.2e-06 26.0 8.8 1.8 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KXZ49999.1 - 9.9e-06 25.6 10.3 9.9e-06 25.6 10.3 2.5 2 0 0 2 2 2 1 MYND finger PDEase_I PF00233.19 KXZ50000.1 - 1.6e-48 165.5 0.2 1.5e-31 109.9 1.2 2.0 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase BolA PF01722.18 KXZ50001.1 - 1.3e-06 28.6 0.0 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein SAP PF02037.27 KXZ50002.1 - 1.3e-07 31.2 0.1 2.3e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 SAP domain FANC_SAP PF18081.1 KXZ50002.1 - 0.11 12.7 0.4 0.4 10.9 0.4 2.0 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain GTP_EFTU PF00009.27 KXZ50003.1 - 3.3e-53 180.1 0.0 5.4e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ion_trans PF00520.31 KXZ50003.1 - 4.4e-07 29.4 10.0 8.1e-07 28.5 10.0 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KXZ50003.1 - 0.0001 22.8 0.3 1.3 9.7 0.4 4.3 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ50003.1 - 0.00018 21.7 2.1 7.3 7.0 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 KXZ50003.1 - 0.00077 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PKD_channel PF08016.12 KXZ50003.1 - 0.0045 15.7 9.9 0.0032 16.2 8.4 1.4 1 1 0 1 1 1 1 Polycystin cation channel AIG1 PF04548.16 KXZ50003.1 - 0.072 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Ank PF00023.30 KXZ50003.1 - 0.075 13.5 1.8 11 6.7 0.1 3.5 3 0 0 3 3 3 0 Ankyrin repeat EFG_II PF14492.6 KXZ50004.1 - 2.3e-25 88.4 0.0 2.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KXZ50004.1 - 4.4e-07 29.8 0.0 5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 KXZ50004.1 - 1.7e-06 27.8 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV Peptidase_C1 PF00112.23 KXZ50005.1 - 3e-20 73.3 8.6 2.8e-10 40.7 3.9 2.5 1 1 1 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KXZ50005.1 - 0.091 11.5 1.5 2.5 6.8 0.4 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Glyco_hydro_9 PF00759.19 KXZ50006.1 - 4.1e-63 214.2 6.4 5.1e-63 213.9 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DSPc PF00782.20 KXZ50007.1 - 1.2e-27 96.3 0.0 1.4e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXZ50007.1 - 0.021 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXZ50007.1 - 0.042 14.0 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 KXZ50007.1 - 0.042 14.2 0.0 0.051 13.9 0.0 1.1 1 0 0 1 1 1 0 Rit1 DUSP-like domain Pkinase_Tyr PF07714.17 KXZ50009.1 - 2.2e-43 148.4 0.0 5.7e-36 124.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50009.1 - 2.8e-34 118.7 0.0 1.1e-26 93.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain GAF PF01590.26 KXZ50009.1 - 1.7e-06 28.7 0.0 6.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KXZ50009.1 - 9.8e-05 22.7 0.2 0.001 19.4 0.0 2.8 3 0 0 3 3 3 1 GAF domain Pkinase_fungal PF17667.1 KXZ50009.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PAS PF00989.25 KXZ50009.1 - 0.0048 16.9 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KXZ50009.1 - 0.0064 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KXZ50009.1 - 0.063 13.5 0.0 0.46 10.7 0.0 2.4 3 0 0 3 3 3 0 PAS fold APH PF01636.23 KXZ50009.1 - 0.089 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXZ50009.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Nucleoporin_N PF08801.11 KXZ50010.1 - 2e-49 168.6 0.0 1.7e-46 158.9 0.0 2.5 1 1 1 2 2 2 2 Nup133 N terminal like DHHC PF01529.20 KXZ50012.1 - 1.7e-32 112.4 2.4 1.7e-32 112.4 2.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Clat_adaptor_s PF01217.20 KXZ50013.1 - 5.6e-43 146.3 1.4 6.3e-43 146.1 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Cas_St_Csn2 PF16813.5 KXZ50013.1 - 0.00023 20.4 1.0 0.00028 20.1 1.0 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Csn2 subfamily St Pribosyltran_N PF13793.6 KXZ50014.1 - 8.8e-11 41.8 0.0 6.5e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXZ50014.1 - 9.9e-08 31.6 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 KXZ50014.1 - 0.0098 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Ran_BP1 PF00638.18 KXZ50015.1 - 4.6e-45 152.8 3.2 4.6e-45 152.8 3.2 1.7 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KXZ50015.1 - 0.0011 18.8 0.7 0.0031 17.4 0.7 1.7 1 1 0 1 1 1 1 WH1 domain Pkinase PF00069.25 KXZ50017.1 - 2e-36 125.7 0.0 2.7e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50017.1 - 5.2e-33 114.4 0.0 2.6e-23 82.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase GAF PF01590.26 KXZ50017.1 - 0.038 14.6 0.1 16 6.1 0.0 3.0 2 0 0 2 2 2 0 GAF domain Kdo PF06293.14 KXZ50017.1 - 0.043 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-MYND PF01753.18 KXZ50018.1 - 3.8e-07 30.1 6.4 6e-07 29.5 6.4 1.3 1 0 0 1 1 1 1 MYND finger HALZ PF02183.18 KXZ50018.1 - 0.0002 21.5 7.2 0.52 10.6 0.7 3.2 1 1 2 3 3 3 3 Homeobox associated leucine zipper Laminin_I PF06008.14 KXZ50018.1 - 0.00055 19.7 2.2 0.00076 19.3 2.2 1.2 1 0 0 1 1 1 1 Laminin Domain I CENP-F_leu_zip PF10473.9 KXZ50018.1 - 0.0045 17.0 1.1 0.0068 16.4 1.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KXZ50018.1 - 0.27 10.1 0.5 0.34 9.7 0.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4795 PF16043.5 KXZ50018.1 - 0.57 9.7 2.6 1.4 8.5 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) APG6_N PF17675.1 KXZ50018.1 - 0.7 10.4 7.3 1.1 9.8 7.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Sipho_Gp157 PF05565.11 KXZ50018.1 - 1.3 9.0 11.7 15 5.6 11.9 2.0 1 1 0 1 1 1 0 Siphovirus Gp157 Nup54 PF13874.6 KXZ50018.1 - 1.5 8.9 4.4 34 4.5 4.4 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Erythro_esteras PF05139.14 KXZ50018.1 - 6.5 6.5 10.0 8.8 6.0 10.0 1.1 1 0 0 1 1 1 0 Erythromycin esterase Exonuc_VII_L PF02601.15 KXZ50019.1 - 0.00031 20.4 0.5 0.00031 20.4 0.5 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF812 PF05667.11 KXZ50019.1 - 0.00039 19.5 8.4 0.00049 19.1 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3552 PF12072.8 KXZ50019.1 - 0.0014 18.1 18.9 0.0021 17.5 18.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) UPF0449 PF15136.6 KXZ50019.1 - 0.013 16.0 9.4 0.086 13.3 9.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Jnk-SapK_ap_N PF09744.9 KXZ50019.1 - 0.015 15.5 16.4 0.015 15.5 16.4 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 AAA_13 PF13166.6 KXZ50019.1 - 0.051 12.2 10.2 0.071 11.8 10.2 1.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXZ50019.1 - 0.063 13.8 13.1 0.1 13.1 13.1 1.4 1 0 0 1 1 1 0 AAA domain eIF-4B PF06273.11 KXZ50019.1 - 0.098 11.7 13.2 0.14 11.1 12.6 1.5 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B Borrelia_P83 PF05262.11 KXZ50019.1 - 0.13 10.7 7.5 0.17 10.3 7.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Atg14 PF10186.9 KXZ50019.1 - 0.49 9.4 17.7 0.78 8.8 17.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 KXZ50019.1 - 0.65 8.8 1.9 0.81 8.5 1.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 KXZ50019.1 - 1.7 7.9 6.4 3 7.1 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KXZ50019.1 - 2.2 8.3 18.9 3.8 7.6 18.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SpoU_sub_bind PF08032.12 KXZ50019.1 - 2.5 8.4 6.7 1.9 8.8 0.0 2.8 2 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding bZIP_2 PF07716.15 KXZ50019.1 - 3.9 7.6 29.3 3.6 7.7 8.6 2.6 1 1 1 2 2 2 0 Basic region leucine zipper S1 PF00575.23 KXZ50020.1 - 2.3e-37 127.2 4.9 1.5e-18 66.9 0.5 3.2 3 0 0 3 3 3 3 S1 RNA binding domain PCB_OB PF17092.5 KXZ50020.1 - 0.0021 18.8 0.4 7.6 7.3 0.1 3.2 2 1 1 3 3 3 2 Penicillin-binding protein OB-like domain S1_2 PF13509.6 KXZ50020.1 - 0.024 14.7 0.2 2.3 8.4 0.1 3.1 2 1 0 2 2 2 0 S1 domain KOW PF00467.29 KXZ50020.1 - 0.18 11.8 2.5 21 5.2 0.3 3.5 2 1 0 2 2 2 0 KOW motif RNase_II_C_S1 PF18614.1 KXZ50020.1 - 1.5 8.8 11.3 3.1 7.8 0.5 4.2 4 0 0 4 4 4 0 RNase II-type exonuclease C-terminal S1 domain S1 PF00575.23 KXZ50021.1 - 0.00079 19.7 0.2 0.0011 19.2 0.2 1.2 1 0 0 1 1 1 1 S1 RNA binding domain DUF3090 PF11290.8 KXZ50021.1 - 0.0073 16.1 0.2 0.0085 15.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3090) Ank_2 PF12796.7 KXZ50023.1 - 7.4e-11 42.5 7.1 0.0039 17.7 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ50023.1 - 0.00021 21.5 5.3 89 4.2 0.0 7.2 8 0 0 8 8 8 0 Ankyrin repeat Ank_4 PF13637.6 KXZ50023.1 - 0.0075 16.8 13.0 2.1 9.0 0.1 5.8 4 2 4 8 8 8 2 Ankyrin repeats (many copies) DUF434 PF04256.12 KXZ50023.1 - 0.03 14.0 0.1 1.1 9.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF434) Ank_5 PF13857.6 KXZ50023.1 - 0.7 10.3 12.1 4.1 7.9 0.2 5.0 3 2 4 7 7 7 0 Ankyrin repeats (many copies) SpoU_methylase PF00588.19 KXZ50024.1 - 1.5e-26 93.2 0.0 1.4e-25 90.1 0.0 2.1 1 1 0 1 1 1 1 SpoU rRNA Methylase family FoP_duplication PF13865.6 KXZ50024.1 - 3.5 8.3 5.9 2 9.1 2.3 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 zf-MYND PF01753.18 KXZ50025.1 - 1.3e-06 28.3 8.8 3.8e-06 26.9 8.8 1.8 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ50026.1 - 1.1e-07 31.8 6.8 2.9e-07 30.5 6.8 1.7 1 0 0 1 1 1 1 MYND finger Peptidase_C1 PF00112.23 KXZ50027.1 - 6.3e-21 75.5 8.2 1.2e-14 55.0 0.2 2.1 1 1 1 2 2 2 2 Papain family cysteine protease zf-MYND PF01753.18 KXZ50028.1 - 1.5e-06 28.2 9.5 4.4e-06 26.7 9.5 1.9 1 0 0 1 1 1 1 MYND finger P_proprotein PF01483.20 KXZ50029.1 - 4.3e-29 100.4 0.5 8.5e-07 28.9 0.0 5.5 4 2 0 4 4 4 4 Proprotein convertase P-domain P_proprotein PF01483.20 KXZ50030.1 - 2.3e-28 98.0 0.2 1.4e-07 31.4 0.0 5.5 5 1 0 5 5 5 5 Proprotein convertase P-domain zf-MYND PF01753.18 KXZ50031.1 - 3.9e-06 26.8 8.6 8e-06 25.9 8.6 1.6 1 0 0 1 1 1 1 MYND finger DUF1929 PF09118.11 KXZ50034.1 - 1.6e-22 79.6 0.0 3.8e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 KXZ50034.1 - 4.6e-19 68.6 0.0 1.5e-18 66.9 0.0 1.9 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 KXZ50034.1 - 0.0045 17.0 4.4 3 7.9 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KXZ50034.1 - 0.012 15.1 0.0 0.074 12.6 0.0 2.5 2 1 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 KXZ50034.1 - 0.14 12.2 0.2 82 3.4 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 KXZ50034.1 - 0.27 11.6 7.2 4 7.9 0.0 4.8 5 1 1 6 6 6 0 Kelch motif Mito_carr PF00153.27 KXZ50035.1 - 2.5e-19 69.0 0.1 3.4e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein LrgB PF04172.16 KXZ50036.1 - 4.4e-13 49.3 3.2 4.4e-13 49.3 3.2 2.3 1 1 0 2 2 2 2 LrgB-like family Ribosomal_S6e PF01092.19 KXZ50037.1 - 1.1e-55 187.0 0.1 2.4e-55 185.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e DUF4574 PF15141.6 KXZ50037.1 - 0.054 13.4 4.1 0.12 12.3 4.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF4385 PF14328.6 KXZ50037.1 - 0.37 10.9 6.5 0.55 10.3 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) CPP1-like PF11833.8 KXZ50037.1 - 5.7 6.6 6.3 8.7 5.9 6.3 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Methyltransf_25 PF13649.6 KXZ50038.1 - 4e-13 49.9 0.0 6.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ50038.1 - 6.8e-11 42.2 0.0 9.7e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KXZ50038.1 - 8.1e-10 38.7 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KXZ50038.1 - 9.9e-10 39.0 0.0 2.5e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ50038.1 - 7.4e-08 33.0 0.0 1.5e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ50038.1 - 1e-07 31.9 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ50038.1 - 2.9e-05 23.7 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KXZ50038.1 - 0.00016 21.5 0.0 0.00031 20.6 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF938) TehB PF03848.14 KXZ50038.1 - 0.0019 17.6 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KXZ50038.1 - 0.02 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KXZ50038.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HTH_17 PF12728.7 KXZ50038.1 - 0.1 12.8 0.0 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_4 PF02390.17 KXZ50038.1 - 0.12 11.9 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Met_10 PF02475.16 KXZ50038.1 - 0.23 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ank_2 PF12796.7 KXZ50039.1 - 4.3e-18 65.7 2.8 2.6e-17 63.2 3.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ50039.1 - 7.7e-15 55.1 1.0 4.1e-09 36.8 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50039.1 - 1.9e-14 52.4 0.4 0.0012 19.1 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KXZ50039.1 - 3e-14 52.7 5.3 0.00016 22.0 0.3 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ50039.1 - 2.6e-10 40.3 6.9 9.9e-06 25.7 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) HTH_16 PF12645.7 KXZ50039.1 - 0.0025 17.8 0.5 4.8 7.3 0.0 3.1 3 0 0 3 3 3 2 Helix-turn-helix domain Methyltransf_25 PF13649.6 KXZ50040.1 - 2.8e-16 60.0 0.0 6e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ50040.1 - 2e-12 47.6 0.0 4.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ50040.1 - 9.2e-11 41.8 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ50040.1 - 1.9e-10 41.4 0.0 3.5e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ50040.1 - 3.9e-09 36.6 0.0 6.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KXZ50040.1 - 7.5e-07 29.0 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KXZ50040.1 - 8e-06 25.5 0.1 1.3e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXZ50040.1 - 0.00044 19.7 0.0 0.00063 19.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KXZ50040.1 - 0.0016 18.3 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) TehB PF03848.14 KXZ50040.1 - 0.007 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 KXZ50040.1 - 0.023 14.2 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_18 PF12847.7 KXZ50040.1 - 0.23 11.4 0.0 0.37 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ham1p_like PF01725.16 KXZ50041.1 - 3.8e-42 144.3 0.0 4.2e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Methyltransf_25 PF13649.6 KXZ50042.1 - 9.2e-15 55.1 0.0 1.4e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ50042.1 - 8.1e-11 42.4 0.0 1.3e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ50042.1 - 1.2e-10 41.4 0.0 2.5e-10 40.4 0.0 1.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ50042.1 - 1e-09 38.4 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ50042.1 - 1.3e-09 38.7 0.0 1.7e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ50042.1 - 1.4e-06 27.9 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 KXZ50042.1 - 0.00043 20.0 0.0 0.002 17.8 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 KXZ50042.1 - 0.00076 18.9 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 KXZ50042.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 KXZ50042.1 - 0.062 12.8 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.12 KXZ50042.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) ADH_zinc_N PF00107.26 KXZ50042.1 - 0.15 12.0 0.1 0.61 10.1 0.1 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_18 PF12847.7 KXZ50042.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain FKBP_C PF00254.28 KXZ50043.1 - 2.4e-17 63.0 0.0 3.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase E1_DerP2_DerF2 PF02221.15 KXZ50044.1 - 5.2e-16 59.3 0.0 6.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KXZ50044.1 - 0.0012 19.3 0.0 0.0017 18.8 0.0 1.3 1 1 0 1 1 1 1 ML-like domain RRM_1 PF00076.22 KXZ50045.1 - 5.4e-19 67.8 0.0 1.1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ50045.1 - 0.007 16.0 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ50045.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Pkinase PF00069.25 KXZ50046.1 - 1.5e-29 103.2 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50046.1 - 8.7e-13 48.1 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ50046.1 - 1.1e-05 25.5 1.1 1.1e-05 25.5 1.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Collagen_bind_2 PF12904.7 KXZ50047.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase SPT2 PF08243.11 KXZ50048.1 - 2.3e-16 60.3 18.9 3e-16 59.9 18.9 1.1 1 0 0 1 1 1 1 SPT2 chromatin protein Chisel PF15355.6 KXZ50048.1 - 0.59 10.4 0.1 0.59 10.4 0.1 2.1 2 1 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel VPS11_C PF12451.8 KXZ50049.1 - 7.5e-11 42.1 0.1 1.4e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 KXZ50049.1 - 2.1e-07 30.9 0.0 0.036 13.9 0.0 3.3 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 KXZ50049.1 - 0.0087 16.1 0.7 0.024 14.7 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger Zn-ribbon_8 PF09723.10 KXZ50049.1 - 0.019 15.1 0.5 0.048 13.8 0.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TPR_11 PF13414.6 KXZ50049.1 - 0.026 14.2 1.2 0.098 12.4 0.1 2.3 2 0 0 2 2 2 0 TPR repeat PX PF00787.24 KXZ50050.1 - 9.7e-15 54.5 0.0 1.5e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KXZ50050.1 - 0.17 11.4 0.2 0.94 9.0 0.2 1.9 1 1 0 1 1 1 0 Vps5 C terminal like LRR_4 PF12799.7 KXZ50051.1 - 1.9e-08 34.5 0.0 0.0058 17.0 0.0 3.6 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.6 KXZ50051.1 - 0.00016 22.1 0.0 0.00022 21.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_9 PF14580.6 KXZ50051.1 - 0.0032 17.0 0.0 0.2 11.1 0.0 2.8 3 0 0 3 3 3 1 Leucine-rich repeat LRR_8 PF13855.6 KXZ50051.1 - 0.0041 16.8 0.1 11 5.9 0.0 3.7 4 1 0 4 4 4 2 Leucine rich repeat Glyco_transf_9 PF01075.17 KXZ50051.1 - 0.091 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) zf-MYND PF01753.18 KXZ50052.1 - 3.3e-07 30.3 10.0 9.2e-07 28.9 10.0 1.8 1 0 0 1 1 1 1 MYND finger SBP_bac_11 PF13531.6 KXZ50057.1 - 5.3e-33 114.7 0.7 5.3e-33 114.7 0.7 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXZ50057.1 - 3.9e-10 40.2 0.4 9.5e-10 38.9 0.3 1.8 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 KXZ50057.1 - 0.0016 17.6 0.0 0.0034 16.5 0.0 1.6 1 0 0 1 1 1 1 PBP superfamily domain PA PF02225.22 KXZ50058.1 - 7.6e-08 32.3 0.2 3.1e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 PA domain DUF3789 PF12664.7 KXZ50058.1 - 0.6 9.9 3.6 1.3 8.8 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) PPI_Ypi1 PF07491.11 KXZ50059.1 - 3.8e-17 61.9 3.9 7e-17 61.0 3.9 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor Moulting_cycle PF04870.16 KXZ50059.1 - 0.13 11.6 1.4 0.15 11.3 1.4 1.1 1 0 0 1 1 1 0 Moulting cycle DUF2729 PF10870.8 KXZ50059.1 - 0.17 11.8 1.7 0.27 11.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) FAM183 PF14886.6 KXZ50060.1 - 3.7e-24 85.5 0.1 4.4e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related Nuc_sug_transp PF04142.15 KXZ50061.1 - 6.7e-34 117.5 10.1 8.6e-34 117.1 10.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXZ50061.1 - 0.0014 17.9 13.1 0.0024 17.1 13.1 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXZ50061.1 - 0.61 10.2 26.9 1.7 8.9 12.2 2.6 2 1 0 2 2 2 0 EamA-like transporter family DUF2358 PF10184.9 KXZ50062.1 - 7.1e-14 52.0 0.0 9.6e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KXZ50062.1 - 0.00017 22.1 0.0 0.00028 21.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain CDP-OH_P_transf PF01066.21 KXZ50063.1 - 6.8e-15 55.6 0.8 6.8e-15 55.6 0.8 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase_Tyr PF07714.17 KXZ50065.1 - 1.2e-38 132.9 0.0 6.9e-30 104.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50065.1 - 1.2e-32 113.3 0.0 1.4e-30 106.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50066.1 - 8.5e-07 28.5 0.0 1e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase VasL PF12486.8 KXZ50066.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL VSG_B PF13206.6 KXZ50066.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain NAD_binding_10 PF13460.6 KXZ50067.1 - 2.1e-06 27.7 0.0 3.8e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DNA_ligase_A_C PF04679.15 KXZ50068.1 - 0.17 12.5 0.0 0.18 12.4 0.0 1.1 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region ParcG PF10274.9 KXZ50069.1 - 5.9e-20 72.2 0.0 1.2e-19 71.2 0.0 1.4 2 0 0 2 2 2 1 Parkin co-regulated protein Aldo_ket_red PF00248.21 KXZ50070.1 - 7.6e-46 156.6 0.0 2e-25 89.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family CAF1 PF04857.20 KXZ50071.1 - 6.3e-65 219.4 0.0 7.9e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease 2-oxogl_dehyd_N PF16078.5 KXZ50071.1 - 0.083 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus zf-MYND PF01753.18 KXZ50072.1 - 2.7e-07 30.5 10.2 2.7e-07 30.5 10.2 1.9 2 0 0 2 2 2 1 MYND finger Rft-1 PF04506.13 KXZ50073.1 - 1.1e-41 143.2 0.0 1.2e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Rft protein Rft-1 PF04506.13 KXZ50074.1 - 1.3e-13 50.6 0.0 1.3e-06 27.4 0.0 2.0 1 1 1 2 2 2 2 Rft protein SAD_SRA PF02182.17 KXZ50075.1 - 9.6e-41 139.1 0.1 6.6e-31 107.1 0.0 2.5 2 0 0 2 2 2 2 SAD/SRA domain zf-C3HC4 PF00097.25 KXZ50075.1 - 6.5e-09 35.5 10.5 0.0004 20.2 0.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ50075.1 - 1.8e-08 34.3 10.1 6.7e-05 22.8 1.0 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXZ50075.1 - 7.1e-08 32.2 15.3 9.2e-05 22.2 7.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ50075.1 - 7.7e-08 32.1 16.2 0.00091 19.0 2.3 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ50075.1 - 3.6e-06 27.2 9.7 0.006 16.9 2.7 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 KXZ50075.1 - 2.9e-05 23.9 18.2 0.00039 20.3 2.5 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXZ50075.1 - 0.00014 22.0 15.9 0.013 15.7 1.3 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXZ50075.1 - 0.00019 21.2 13.6 0.00087 19.1 1.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Mpp10 PF04006.12 KXZ50075.1 - 0.001 17.7 5.6 0.001 17.7 5.6 1.9 3 0 0 3 3 3 1 Mpp10 protein zf-RING_10 PF16685.5 KXZ50075.1 - 0.17 12.0 9.0 0.3 11.3 1.2 2.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXZ50075.1 - 0.43 10.4 11.2 1.4 8.8 6.2 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CDC45 PF02724.14 KXZ50075.1 - 6.1 5.0 13.0 0.042 12.1 4.7 1.6 2 0 0 2 2 2 0 CDC45-like protein Apolipoprotein PF01442.18 KXZ50076.1 - 3e-06 27.2 14.2 3.8e-06 26.9 14.2 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 KXZ50076.1 - 0.0065 16.5 2.8 0.082 13.0 2.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Hydin_ADK PF17213.3 KXZ50076.1 - 0.016 15.5 4.3 0.021 15.1 4.3 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF3584 PF12128.8 KXZ50076.1 - 0.031 11.8 14.7 0.039 11.5 14.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OpcA PF07239.11 KXZ50076.1 - 0.056 13.1 0.2 0.07 12.8 0.2 1.1 1 0 0 1 1 1 0 Outer membrane protein OpcA DUF5595 PF18077.1 KXZ50076.1 - 0.63 10.2 4.9 4.3 7.5 0.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) HIP1_clath_bdg PF16515.5 KXZ50076.1 - 1.3 9.6 20.1 19 5.9 9.8 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF616 PF04765.13 KXZ50076.1 - 2 7.6 4.2 3.2 6.9 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF616) DUF2130 PF09903.9 KXZ50076.1 - 2 7.6 11.4 0.61 9.3 5.9 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Mitofilin PF09731.9 KXZ50076.1 - 2.5 6.8 18.3 3.8 6.2 6.2 2.0 1 1 1 2 2 2 0 Mitochondrial inner membrane protein DUF4455 PF14643.6 KXZ50076.1 - 3 6.4 14.1 6.5 5.3 14.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4455) UPF0242 PF06785.11 KXZ50076.1 - 4.2 7.4 11.3 62 3.6 11.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GCP_N_terminal PF17681.1 KXZ50079.1 - 1.7e-56 192.1 0.0 1e-55 189.6 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXZ50079.1 - 1.9e-26 93.3 0.0 2.6e-21 76.4 0.0 2.2 1 1 1 2 2 2 2 Gamma tubulin complex component C-terminal Dscam_C PF12355.8 KXZ50079.1 - 5.4 8.0 6.4 9.9 7.1 2.6 2.6 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Glyco_hydro_77 PF02446.17 KXZ50081.1 - 9.6e-101 337.9 0.1 1.2e-100 337.6 0.1 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 KXZ50081.1 - 7.4e-13 48.2 0.0 2.7e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Starch binding domain Ank_2 PF12796.7 KXZ50082.1 - 0.0036 17.9 0.2 3 8.5 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) FKBP_C PF00254.28 KXZ50083.1 - 8.9e-12 45.2 0.0 1.3e-11 44.6 0.0 1.3 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Fasciclin PF02469.22 KXZ50084.1 - 2.1e-07 31.2 0.0 2.3e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain ALGX PF16822.5 KXZ50084.1 - 0.093 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Notch PF00066.17 KXZ50086.1 - 0.14 12.6 9.2 0.016 15.6 3.6 2.3 2 0 0 2 2 2 0 LNR domain EF-hand_6 PF13405.6 KXZ50086.1 - 1.8 8.7 4.7 9.6 6.4 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 KXZ50086.1 - 2.6 7.7 6.2 0.37 10.4 0.2 2.6 3 0 0 3 3 3 0 EF hand PTP_N PF12453.8 KXZ50087.1 - 0.072 12.8 0.5 0.36 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal PSI PF01437.25 KXZ50087.1 - 2.4 8.8 28.2 0.12 12.9 5.4 3.8 3 2 0 3 3 3 0 Plexin repeat Paramecium_SA PF01508.16 KXZ50087.1 - 8.2 6.9 37.0 0.13 12.7 8.2 4.6 5 0 0 5 5 5 0 Paramecium surface antigen domain ABC2_membrane PF01061.24 KXZ50089.1 - 1.2e-28 100.0 15.6 1.2e-28 100.0 15.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ50089.1 - 6.9e-25 88.2 0.0 1.1e-24 87.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ50089.1 - 6.7e-07 29.4 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXZ50089.1 - 9.2e-05 21.7 15.2 9.2e-05 21.7 15.2 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 KXZ50089.1 - 0.00014 21.5 0.1 0.00042 20.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXZ50089.1 - 0.00033 20.6 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXZ50089.1 - 0.00067 20.1 0.4 0.0056 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KXZ50089.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ50089.1 - 0.012 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 KXZ50089.1 - 0.022 14.6 0.1 0.068 13.1 0.1 1.8 1 0 0 1 1 1 0 CDR ABC transporter AAA_23 PF13476.6 KXZ50089.1 - 0.028 14.9 0.0 0.05 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXZ50089.1 - 0.13 12.5 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KXZ50089.1 - 0.13 11.7 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KXZ50089.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ50089.1 - 0.17 12.4 0.2 0.34 11.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain ketoacyl-synt PF00109.26 KXZ50090.1 - 7.3e-55 186.3 0.3 9.4e-54 182.6 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXZ50090.1 - 1.4e-30 105.8 1.0 2.7e-30 104.8 1.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXZ50090.1 - 0.00024 20.5 0.2 0.001 18.5 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KXZ50090.1 - 0.027 14.3 0.3 2 8.3 0.2 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glycos_transf_1 PF00534.20 KXZ50092.1 - 1.3e-30 106.2 0.0 1.3e-26 93.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ50092.1 - 2.5e-16 60.3 0.1 9.9e-16 58.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ50092.1 - 7e-13 48.9 1.1 1.5e-12 47.8 0.3 2.0 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXZ50092.1 - 2.4e-07 31.4 3.4 2.4e-07 31.4 3.4 2.8 2 2 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXZ50092.1 - 1.1e-05 25.8 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 VIR_N PF15912.5 KXZ50095.1 - 0.82 9.2 12.8 1.1 8.8 12.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4604 PF15377.6 KXZ50095.1 - 0.99 9.8 36.9 4.9 7.6 33.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) SAPS PF04499.15 KXZ50095.1 - 1.8 7.2 8.2 2.3 6.9 8.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 KXZ50095.1 - 2.1 8.1 18.7 3.8 7.2 18.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 KXZ50095.1 - 4.3 7.3 6.9 7 6.6 6.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAD_binding_3 PF01494.19 KXZ50097.1 - 4.8e-13 49.1 0.2 2e-08 33.9 0.5 2.5 3 0 0 3 3 3 2 FAD binding domain Guanylate_cyc PF00211.20 KXZ50098.1 - 2.9e-55 186.7 0.0 4.5e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FXR_C1 PF16096.5 KXZ50098.1 - 0.026 14.7 6.6 0.072 13.3 6.6 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 PT-TG PF14449.6 KXZ50099.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Pre-toxin TG Guanylate_cyc PF00211.20 KXZ50100.1 - 9.1e-55 185.1 0.0 1.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF5364 PF17322.2 KXZ50101.1 - 0.0058 17.0 7.9 0.0073 16.6 7.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5364) Sec23_helical PF04815.15 KXZ50101.1 - 0.043 13.6 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Sec23/Sec24 helical domain BcrAD_BadFG PF01869.20 KXZ50101.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DEC-1_N PF04625.13 KXZ50101.1 - 2.2 7.2 14.1 3.5 6.5 2.4 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Guanylate_cyc PF00211.20 KXZ50103.1 - 1.3e-38 132.4 0.0 1.9e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain zf-CCCH PF00642.24 KXZ50104.1 - 3.4e-27 93.8 22.7 4e-10 39.3 4.1 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXZ50104.1 - 1.7e-17 62.9 23.7 5.2e-06 26.3 1.8 3.5 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 KXZ50104.1 - 2e-15 56.2 21.7 1.5e-06 27.8 1.0 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KXZ50104.1 - 2.5e-06 27.8 19.6 0.0058 17.1 2.3 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KXZ50104.1 - 0.00023 21.8 20.0 0.23 12.1 0.4 4.2 3 1 1 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 KXZ50104.1 - 0.036 14.3 9.2 1.6 9.0 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger containing family Lustrin_cystein PF14625.6 KXZ50104.1 - 0.51 10.7 7.1 9.2 6.7 0.2 3.2 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain AAA PF00004.29 KXZ50106.1 - 8.4e-42 142.7 0.0 2.2e-41 141.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ50106.1 - 4.5e-11 42.4 1.1 1e-10 41.2 1.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXZ50106.1 - 5.3e-05 23.7 3.3 0.025 15.0 0.2 3.3 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.13 KXZ50106.1 - 9.2e-05 21.8 0.1 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KXZ50106.1 - 0.00029 20.6 0.0 0.00069 19.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ50106.1 - 0.0006 20.1 0.1 0.0084 16.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXZ50106.1 - 0.00082 19.4 0.0 0.0025 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXZ50106.1 - 0.001 19.3 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXZ50106.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXZ50106.1 - 0.0028 17.8 0.0 0.0072 16.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) FtsH_ext PF06480.15 KXZ50106.1 - 0.0075 16.6 0.3 0.046 14.1 0.3 2.2 1 1 0 1 1 1 1 FtsH Extracellular Mg_chelatase PF01078.21 KXZ50106.1 - 0.011 15.1 0.2 0.022 14.1 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXZ50106.1 - 0.016 15.4 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXZ50106.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXZ50106.1 - 0.048 13.2 0.1 0.12 11.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KXZ50106.1 - 0.052 13.6 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXZ50106.1 - 0.068 13.7 0.0 0.068 13.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain MCM PF00493.23 KXZ50106.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain PhoH PF02562.16 KXZ50106.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.13 KXZ50106.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KXZ50106.1 - 0.17 12.4 0.2 0.29 11.6 0.2 1.4 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KXZ50106.1 - 3.7 7.1 7.7 0.14 11.7 0.1 2.4 3 1 0 3 3 3 0 AAA domain NYN_YacP PF05991.11 KXZ50109.1 - 2e-09 37.6 1.5 2e-09 37.6 1.5 2.3 2 1 0 2 2 2 1 YacP-like NYN domain PNTB PF02233.16 KXZ50109.1 - 0.044 12.7 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Acetyltransf_6 PF13480.7 KXZ50109.1 - 0.078 13.1 5.8 3.1 8.0 0.3 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_S11 PF00768.20 KXZ50109.1 - 0.16 11.3 0.4 0.84 9.0 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase GYF PF02213.16 KXZ50110.1 - 1.1e-18 66.6 10.2 9.2e-10 38.0 1.7 2.4 2 0 0 2 2 2 2 GYF domain GYF_2 PF14237.6 KXZ50110.1 - 0.0017 18.1 3.6 0.26 11.1 0.3 2.7 2 0 0 2 2 2 2 GYF domain 2 ARL2_Bind_BART PF11527.8 KXZ50112.1 - 8.9e-33 112.8 0.3 1.4e-32 112.2 0.3 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Mito_fiss_reg PF05308.11 KXZ50112.1 - 1.3 9.1 8.5 1.5 8.9 7.8 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator MAGE PF01454.19 KXZ50113.1 - 7.2e-12 45.5 0.0 9.2e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 MAGE family UBA2_C PF16195.5 KXZ50113.1 - 0.034 14.8 0.5 0.034 14.8 0.5 2.5 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus CBS PF00571.28 KXZ50115.1 - 8.2e-26 90.2 0.3 1.1e-13 51.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF393 PF04134.12 KXZ50115.1 - 3e-21 76.8 0.0 5.9e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF393 PRC PF05239.16 KXZ50115.1 - 0.003 17.6 0.6 2.8 8.1 0.2 2.8 3 0 0 3 3 3 2 PRC-barrel domain Pox_G7 PF05503.12 KXZ50115.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus G7-like FAST_1 PF06743.15 KXZ50116.1 - 0.039 13.9 0.0 0.62 10.0 0.0 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 GTP_cyclohydro2 PF00925.20 KXZ50120.1 - 1.9e-49 167.4 0.0 2.7e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II MMR_HSR1 PF01926.23 KXZ50121.1 - 1.8e-23 82.8 0.0 3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 KXZ50121.1 - 1.2e-13 50.9 22.9 5.5e-07 29.3 9.5 3.8 1 1 1 2 2 2 2 GTP1/OBG FeoB_N PF02421.18 KXZ50121.1 - 1.4e-07 31.1 0.0 4.4e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXZ50121.1 - 0.013 15.6 0.0 3.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 KXZ50121.1 - 0.037 14.3 0.0 27 5.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 KXZ50121.1 - 0.069 12.1 0.0 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KXZ50121.1 - 0.25 10.8 0.0 23 4.4 0.0 2.6 2 1 0 2 2 2 0 ADP-ribosylation factor family Rieske_2 PF13806.6 KXZ50122.1 - 1.2e-20 73.3 0.0 1.7e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain SBF_like PF13593.6 KXZ50123.1 - 1.1e-30 107.0 13.6 1.2e-30 106.9 13.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KXZ50123.1 - 1.2e-07 31.6 11.3 2e-07 30.9 11.0 1.6 1 1 0 1 1 1 1 Sodium Bile acid symporter family Guanylate_cyc PF00211.20 KXZ50125.1 - 3.2e-17 62.8 0.0 3.3e-07 30.1 0.0 3.2 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain CcmD PF04995.14 KXZ50125.1 - 0.03 14.4 2.1 0.077 13.1 2.1 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF3707 PF12499.8 KXZ50126.1 - 1.2e-19 71.3 0.8 1.4e-19 71.1 0.8 1.1 1 0 0 1 1 1 1 Pherophorin Fe_dep_repr_C PF02742.15 KXZ50128.1 - 0.057 13.5 0.1 0.08 13.0 0.1 1.2 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Na_H_Exchanger PF00999.21 KXZ50129.1 - 6.1e-24 84.5 20.6 9.2e-15 54.3 11.0 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family PRIMA1 PF16101.5 KXZ50129.1 - 5.7 7.0 7.7 2.1 8.4 4.0 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 KXZ50131.1 - 9.7e-59 198.9 0.0 1.2e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50131.1 - 1.1e-32 113.4 0.0 1.5e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50131.1 - 3.7e-06 26.5 0.0 2.4e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXZ50131.1 - 2e-05 23.6 0.0 3.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RTC PF01137.21 KXZ50132.1 - 3.1e-56 190.1 0.0 3.5e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KXZ50132.1 - 3.5e-37 127.0 0.1 7.4e-37 126.0 0.1 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF87 PF01935.17 KXZ50134.1 - 0.29 11.2 3.0 0.44 10.6 3.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain rve PF00665.26 KXZ50136.1 - 2.9e-12 46.8 0.0 4.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain PseudoU_synth_1 PF01416.20 KXZ50137.1 - 4.2e-34 117.3 0.0 1.1e-23 83.7 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 KXZ50137.1 - 0.0037 17.1 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Glyco_hydro_14 PF01373.17 KXZ50138.1 - 2.3e-56 191.5 0.0 3.1e-42 144.9 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 IRK_C PF17655.1 KXZ50139.1 - 2.5e-18 66.3 0.1 4.4e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KXZ50139.1 - 2.9e-12 46.6 4.9 1.3e-10 41.3 4.9 2.2 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain TolA_bind_tri PF16331.5 KXZ50139.1 - 0.00032 20.7 0.2 0.00032 20.7 0.2 4.9 1 1 3 5 5 5 1 TolA binding protein trimerisation HMMR_C PF15908.5 KXZ50139.1 - 0.0012 19.1 16.3 0.054 13.8 7.7 2.3 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor C-terminal DivIC PF04977.15 KXZ50139.1 - 0.0024 17.6 1.6 0.0024 17.6 1.6 5.0 2 1 2 5 5 5 1 Septum formation initiator YabA PF06156.13 KXZ50139.1 - 0.0031 18.1 19.4 0.27 11.9 2.8 4.4 1 1 2 3 3 3 1 Initiation control protein YabA Ion_trans_2 PF07885.16 KXZ50139.1 - 0.0043 17.0 2.1 0.0089 16.0 2.1 1.5 1 0 0 1 1 1 1 Ion channel DUF2353 PF09789.9 KXZ50139.1 - 0.013 14.9 23.5 0.094 12.1 18.1 2.4 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Ion_trans PF00520.31 KXZ50139.1 - 0.018 14.2 4.5 0.029 13.6 4.5 1.2 1 0 0 1 1 1 0 Ion transport protein DUF1206 PF06724.11 KXZ50139.1 - 0.032 14.3 0.1 0.12 12.5 0.1 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF2046 PF09755.9 KXZ50139.1 - 0.044 13.0 18.3 0.054 12.7 1.7 3.4 1 1 2 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Rootletin PF15035.6 KXZ50139.1 - 0.36 10.8 25.1 7.5 6.5 12.0 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion MqsA_antitoxin PF15731.5 KXZ50139.1 - 0.45 10.6 1.6 0.63 10.2 0.2 1.9 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Laminin_II PF06009.12 KXZ50139.1 - 0.7 9.9 15.9 0.37 10.8 1.5 3.5 1 1 1 3 3 3 0 Laminin Domain II Cep57_CLD_2 PF14197.6 KXZ50139.1 - 0.83 9.8 29.0 0.72 10.0 3.8 4.3 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 KXZ50139.1 - 1 9.4 26.3 6 6.9 12.1 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KXZ50139.1 - 1.8 7.8 28.6 3.7 6.9 11.8 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.11 KXZ50139.1 - 2.4 6.7 29.2 3.7 6.1 16.9 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF4407 PF14362.6 KXZ50139.1 - 4.3 6.6 28.9 0.21 10.9 8.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KXZ50139.1 - 4.8 7.3 38.1 19 5.3 15.5 3.8 2 1 1 4 4 3 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.8 KXZ50139.1 - 5.5 6.6 34.2 0.076 12.6 0.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) DUF724 PF05266.14 KXZ50139.1 - 6.2 6.6 16.9 6.2 6.6 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) APG6_N PF17675.1 KXZ50139.1 - 6.6 7.3 33.6 2.9 8.4 15.2 3.3 1 1 1 2 2 2 0 Apg6 coiled-coil region TSC22 PF01166.18 KXZ50139.1 - 8.4 6.8 13.9 1.2 9.5 0.5 4.2 4 0 0 4 4 4 0 TSC-22/dip/bun family Spc7 PF08317.11 KXZ50139.1 - 9.4 5.0 29.5 1.6 7.5 15.7 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-B_dimeris PF09026.10 KXZ50140.1 - 0.081 13.3 4.9 0.11 12.9 4.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KXZ50140.1 - 0.89 7.6 3.3 1 7.4 3.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Coatomer_E PF04733.14 KXZ50141.1 - 2.5e-83 279.8 5.6 3.1e-67 227.0 1.2 2.0 1 1 1 2 2 2 2 Coatomer epsilon subunit TPR_1 PF00515.28 KXZ50141.1 - 2.1e-07 30.5 5.6 0.00038 20.2 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ50141.1 - 1.9e-06 28.3 5.4 0.0047 17.4 0.2 3.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ50141.1 - 2.3e-06 27.3 10.4 0.00097 19.1 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ50141.1 - 6.2e-06 26.4 6.9 0.00051 20.3 0.2 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ50141.1 - 0.0025 17.9 0.1 0.14 12.3 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ50141.1 - 0.0033 17.3 0.1 2.3 8.4 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ50141.1 - 0.0039 17.0 0.0 0.35 10.8 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ50141.1 - 0.0094 15.6 0.2 0.37 10.5 0.0 3.1 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 KXZ50141.1 - 0.35 11.2 5.3 26 5.4 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ50141.1 - 0.36 11.6 4.2 15 6.5 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ50141.1 - 0.61 10.8 5.9 7.6 7.3 1.6 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat MoCF_biosynth PF00994.24 KXZ50142.1 - 2e-28 98.8 0.0 3.5e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 KXZ50142.1 - 2e-24 86.6 0.0 3.2e-16 59.9 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family GATase_2 PF00310.21 KXZ50144.1 - 8.6e-169 561.7 0.0 1.1e-168 561.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KXZ50144.1 - 1.4e-146 488.4 0.0 2.1e-145 484.5 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KXZ50144.1 - 3.3e-108 361.4 0.0 3.8e-106 354.6 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KXZ50144.1 - 6.5e-80 267.2 0.6 1.2e-79 266.4 0.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KXZ50144.1 - 5.3e-27 94.8 1.5 9.2e-27 94.0 1.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KXZ50144.1 - 1.4e-21 76.3 0.0 2.7e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KXZ50144.1 - 3.8e-09 36.7 0.0 6.7e-08 32.7 0.1 3.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXZ50144.1 - 5.7e-07 30.0 1.6 9.6e-05 22.9 0.2 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ50144.1 - 2.7e-06 26.7 2.5 5.4e-05 22.5 0.7 2.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KXZ50144.1 - 7.1e-06 25.5 1.3 0.045 13.0 0.1 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXZ50144.1 - 7.8e-06 25.4 0.0 1.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXZ50144.1 - 1.2e-05 25.1 1.2 0.0087 15.7 0.2 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXZ50144.1 - 4.9e-05 22.9 0.9 4.9e-05 22.9 0.9 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXZ50144.1 - 7.6e-05 22.1 0.2 0.059 12.6 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXZ50144.1 - 7.8e-05 21.6 0.9 0.00026 19.8 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 KXZ50144.1 - 0.00078 19.9 1.4 1.8 9.1 0.3 3.6 3 0 0 3 3 3 1 Putative NAD(P)-binding GIDA PF01134.22 KXZ50144.1 - 0.00085 18.5 1.3 0.02 14.0 0.5 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXZ50144.1 - 0.0017 17.6 0.2 0.0035 16.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 KXZ50144.1 - 0.0054 15.2 0.2 0.36 9.2 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like FMN_dh PF01070.18 KXZ50144.1 - 0.0076 15.3 1.0 0.017 14.2 1.0 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AdoHcyase_NAD PF00670.21 KXZ50144.1 - 0.013 15.5 0.9 0.38 10.8 0.1 2.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Thi4 PF01946.17 KXZ50144.1 - 0.024 13.9 0.1 0.069 12.4 0.1 1.7 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 KXZ50144.1 - 0.074 12.4 0.6 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KXZ50144.1 - 0.1 11.6 0.3 0.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Dus PF01207.17 KXZ50145.1 - 4.7e-35 121.2 0.1 2.8e-30 105.5 0.0 2.8 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) F-box-like PF12937.7 KXZ50146.1 - 0.014 15.3 0.1 0.039 13.8 0.1 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXZ50146.1 - 0.035 14.0 0.1 0.094 12.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain TTL PF03133.15 KXZ50147.1 - 1.4e-32 113.0 0.0 2.4e-32 112.2 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ERG4_ERG24 PF01222.17 KXZ50149.1 - 0.05 12.4 0.8 0.063 12.0 0.8 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DHHC PF01529.20 KXZ50149.1 - 0.071 13.2 1.9 0.082 13.0 1.9 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase NicO PF03824.16 KXZ50150.1 - 0.0036 16.7 2.8 0.0049 16.3 2.8 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein GalP_UDP_tr_C PF02744.17 KXZ50150.1 - 0.004 16.9 0.2 0.0057 16.4 0.2 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain SfLAP PF11139.8 KXZ50150.1 - 0.1 12.0 5.7 0.14 11.5 5.7 1.2 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein SelP_N PF04592.14 KXZ50150.1 - 0.18 11.1 3.9 0.24 10.8 3.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PLDc_2 PF13091.6 KXZ50151.1 - 5.5e-13 48.9 0.4 1.2e-08 34.9 0.1 2.2 1 1 1 2 2 2 2 PLD-like domain zf-CCCH PF00642.24 KXZ50151.1 - 0.0035 17.2 2.3 0.0054 16.6 2.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Regulator_TrmB PF11495.8 KXZ50151.1 - 0.026 13.7 0.1 0.033 13.4 0.1 1.1 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Redoxin PF08534.10 KXZ50151.1 - 0.078 12.7 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin PilI PF10623.9 KXZ50151.1 - 0.16 12.1 1.3 0.25 11.5 0.6 1.8 1 1 0 1 1 1 0 Plasmid conjugative transfer protein PilI DEAD PF00270.29 KXZ50152.1 - 1e-62 211.0 0.0 2.8e-48 164.0 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ50152.1 - 2.4e-33 114.8 0.1 6.2e-33 113.5 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ50152.1 - 6.2e-07 29.6 0.0 5.7e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 KXZ50152.1 - 0.11 11.8 0.0 15 4.8 0.0 2.1 2 0 0 2 2 2 0 SBF-like CPA transporter family (DUF4137) Gly_rich PF12810.7 KXZ50152.1 - 0.22 11.4 1.8 0.46 10.3 1.8 1.5 1 0 0 1 1 1 0 Glycine rich protein T4SS-DNA_transf PF02534.14 KXZ50152.1 - 1.6 7.5 4.5 18 4.0 0.0 3.0 4 0 0 4 4 4 0 Type IV secretory system Conjugative DNA transfer PHD PF00628.29 KXZ50153.1 - 1e-08 34.9 2.5 1e-08 34.9 2.5 2.1 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KXZ50153.1 - 6.5e-05 23.2 13.6 0.00012 22.3 3.1 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 KXZ50153.1 - 0.00095 19.4 2.8 0.00095 19.4 2.8 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXZ50153.1 - 0.003 17.4 3.6 0.003 17.4 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ50153.1 - 0.0086 15.9 0.9 0.0086 15.9 0.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KXZ50153.1 - 0.013 15.5 2.8 0.077 13.0 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-ANAPC11 PF12861.7 KXZ50153.1 - 0.027 14.5 4.3 0.27 11.3 0.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KXZ50153.1 - 0.031 14.1 4.0 0.031 14.1 4.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.6 KXZ50153.1 - 0.1 12.2 4.6 0.048 13.3 1.7 1.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 KXZ50153.1 - 0.28 11.1 7.6 0.79 9.7 3.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Rhodanese_C PF12368.8 KXZ50153.1 - 0.76 10.2 5.3 6.1 7.3 0.8 2.3 2 0 0 2 2 2 0 Rhodanase C-terminal Zf_RING PF16744.5 KXZ50153.1 - 6.5 6.9 7.1 0.27 11.4 0.6 2.0 2 0 0 2 2 2 0 KIAA1045 RING finger Trypsin PF00089.26 KXZ50154.1 - 2e-09 37.6 0.1 4.3e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 KXZ50154.1 - 3.5e-08 34.5 0.1 6.5e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KXZ50154.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Amidohydro_1 PF01979.20 KXZ50155.1 - 1.4e-24 87.1 0.0 6.8e-24 84.8 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXZ50155.1 - 4.5e-09 36.3 3.6 2.1e-06 27.5 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Pkinase PF00069.25 KXZ50156.1 - 2.5e-58 197.5 0.0 3.1e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50156.1 - 2.2e-34 118.9 0.0 2.9e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50156.1 - 0.0073 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ50156.1 - 0.009 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KXZ50156.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Guanylate_cyc PF00211.20 KXZ50157.1 - 7.4e-53 178.9 0.0 1.3e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ50158.1 - 1.2e-53 181.4 0.0 2.2e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fumble PF03630.14 KXZ50159.1 - 1.6e-121 405.5 0.3 2.3e-121 405.0 0.3 1.2 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 KXZ50159.1 - 2.3e-30 105.8 0.0 1e-26 93.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function DUF89 MS_channel PF00924.18 KXZ50160.1 - 8.1e-11 41.9 0.0 8.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel LPP PF04728.13 KXZ50161.1 - 0.0087 16.4 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipoprotein leucine-zipper ADIP PF11559.8 KXZ50161.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 KXZ50161.1 - 0.017 15.4 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 TSC-22/dip/bun family NUDE_C PF04880.13 KXZ50161.1 - 0.018 15.5 0.0 0.02 15.4 0.0 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF1640 PF07798.11 KXZ50161.1 - 0.02 15.0 0.1 0.023 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) COMP PF11598.8 KXZ50161.1 - 0.024 15.1 0.1 0.033 14.7 0.1 1.3 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Phlebovirus_NSM PF07246.11 KXZ50161.1 - 0.044 13.2 0.0 0.046 13.1 0.0 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M COG2 PF06148.11 KXZ50161.1 - 0.061 13.4 0.0 0.078 13.1 0.0 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 KXZ50161.1 - 0.078 12.3 0.0 0.083 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rootletin PF15035.6 KXZ50161.1 - 0.078 13.0 0.0 0.093 12.7 0.0 1.0 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.11 KXZ50161.1 - 0.16 12.2 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HALZ PF02183.18 KXZ50161.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 KXZ50161.1 - 0.17 11.9 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 KXZ50161.1 - 0.18 11.4 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 Intermediate filament protein Fumble PF03630.14 KXZ50162.1 - 3.1e-111 371.7 0.7 4e-111 371.4 0.7 1.1 1 0 0 1 1 1 1 Fumble MS_channel PF00924.18 KXZ50163.1 - 1e-06 28.5 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXZ50164.1 - 9.5e-06 24.8 0.0 1.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ50164.1 - 7.6e-05 22.0 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ50164.1 - 0.00027 20.6 0.0 0.00061 19.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ50164.1 - 0.016 15.7 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF4181 PF13789.6 KXZ50164.1 - 1 9.6 9.3 0.37 11.1 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) LRR_4 PF12799.7 KXZ50165.1 - 0.0026 18.1 3.1 0.23 11.9 0.0 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ50165.1 - 0.013 15.5 10.3 0.98 9.6 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat ABC1 PF03109.16 KXZ50166.1 - 1.8e-36 124.9 0.0 4e-36 123.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXZ50166.1 - 0.00095 19.2 0.3 0.025 14.5 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family MatE PF01554.18 KXZ50167.1 - 3.1e-18 66.0 34.1 1.7e-08 34.3 3.5 3.3 2 1 1 3 3 3 3 MatE Polysacc_synt_C PF14667.6 KXZ50167.1 - 2.6e-09 37.3 3.8 2.6e-09 37.3 3.8 3.5 1 1 2 3 3 3 1 Polysaccharide biosynthesis C-terminal domain F-box PF00646.33 KXZ50168.1 - 3.4e-08 33.1 1.0 9.2e-08 31.8 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXZ50168.1 - 0.00014 21.7 3.2 0.00014 21.7 3.2 1.8 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXZ50168.1 - 0.016 15.1 0.1 0.044 13.7 0.1 1.7 2 0 0 2 2 2 0 F-box CAP_N PF01213.19 KXZ50168.1 - 5.8 6.3 5.5 8.4 5.8 5.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 KXZ50169.1 - 1.6e-08 34.2 0.0 0.00015 21.2 0.0 3.2 1 1 1 2 2 2 2 Protein kinase domain 2OG-FeII_Oxy_3 PF13640.6 KXZ50174.1 - 2.9e-21 76.1 0.0 4.9e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ50174.1 - 3.7e-10 40.2 0.0 6.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 KXZ50174.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein ShK PF01549.24 KXZ50174.1 - 0.18 12.4 6.8 0.7 10.5 6.8 2.1 1 1 0 1 1 1 0 ShK domain-like Cu-oxidase_3 PF07732.15 KXZ50175.1 - 1.6e-22 79.8 5.7 1.1e-10 41.6 0.0 5.8 6 1 0 6 6 6 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXZ50175.1 - 4.2e-22 78.4 17.2 1.3e-10 41.1 6.0 6.3 5 2 0 5 5 5 4 Multicopper oxidase Cu-oxidase PF00394.22 KXZ50175.1 - 9.7e-07 29.0 0.1 0.02 15.0 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase NPCBM_assoc PF10633.9 KXZ50175.1 - 0.23 11.7 3.8 11 6.4 0.3 4.0 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Chloroa_b-bind PF00504.21 KXZ50176.1 - 8.3e-40 137.0 0.0 1.1e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HHH PF00633.23 KXZ50176.1 - 0.071 13.0 0.1 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif SET PF00856.28 KXZ50177.1 - 6.9e-13 49.3 0.0 1.6e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXZ50177.1 - 1.9e-12 48.0 0.2 3.4e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding CS PF04969.16 KXZ50178.1 - 5.4e-15 56.2 0.0 7.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 CS domain DUF3493 PF11998.8 KXZ50179.1 - 0.055 13.6 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 RNA_pol_Rpb2_4 PF04566.13 KXZ50179.1 - 0.099 12.9 0.0 0.62 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 TPR_12 PF13424.6 KXZ50181.1 - 3.3e-17 62.5 5.5 3.7e-07 30.3 0.4 5.1 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ50181.1 - 2.5e-16 59.0 17.0 2.1e-06 27.4 0.1 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ50181.1 - 0.066 13.3 3.5 57 4.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 KXZ50181.1 - 0.2 12.0 7.3 0.045 14.1 1.2 3.1 3 1 0 3 3 3 0 AAA ATPase domain Fez1 PF06818.15 KXZ50182.1 - 0.014 15.8 0.3 0.014 15.8 0.3 6.9 2 2 4 6 6 6 0 Fez1 TMF_TATA_bd PF12325.8 KXZ50182.1 - 0.054 13.7 0.4 0.054 13.7 0.4 9.7 5 3 2 9 9 9 0 TATA element modulatory factor 1 TATA binding Pox_A_type_inc PF04508.12 KXZ50182.1 - 2.6 8.1 27.9 1.7 8.6 0.2 8.0 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat Pyr_redox_2 PF07992.14 KXZ50183.1 - 2.6e-55 187.7 0.2 3.4e-55 187.4 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXZ50183.1 - 2.5e-27 95.3 0.1 5.1e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXZ50183.1 - 3.7e-18 65.9 1.3 7e-13 49.0 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ50183.1 - 1.2e-11 44.4 0.1 1.8e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ50183.1 - 1.5e-07 30.9 2.4 1.3e-06 27.7 0.9 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KXZ50183.1 - 1.4e-05 24.6 0.1 3.6e-05 23.3 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXZ50183.1 - 4.9e-05 22.7 0.4 0.00016 21.0 0.4 1.8 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXZ50183.1 - 6.9e-05 21.7 0.4 0.0004 19.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXZ50183.1 - 0.00016 20.9 0.7 0.00029 20.0 0.7 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXZ50183.1 - 0.00049 19.4 0.1 0.019 14.3 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KXZ50183.1 - 0.00051 19.7 8.8 0.023 14.3 8.7 2.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXZ50183.1 - 0.0037 17.4 0.3 0.0037 17.4 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXZ50183.1 - 0.0038 16.3 2.7 0.025 13.7 2.7 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.6 KXZ50183.1 - 0.0077 15.4 0.1 0.047 12.8 0.0 2.1 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.6 KXZ50183.1 - 0.18 12.3 0.2 27 5.3 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Ribophorin_II PF05817.14 KXZ50184.1 - 7.8e-54 183.3 0.0 9.4e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4239 PF14023.6 KXZ50184.1 - 0.17 11.6 4.3 0.33 10.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) RRM_1 PF00076.22 KXZ50185.1 - 3.7e-14 52.3 0.1 6.2e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ50185.1 - 0.0076 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXZ50185.1 - 0.17 12.1 2.5 0.29 11.4 0.0 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Glyco_transf_90 PF05686.12 KXZ50186.1 - 3.2e-10 39.5 1.1 4.6e-09 35.7 0.2 2.6 2 1 1 3 3 3 1 Glycosyl transferase family 90 DUF4607 PF15380.6 KXZ50186.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) Glyco_transf_90 PF05686.12 KXZ50187.1 - 4.1e-23 82.0 0.2 9.2e-22 77.5 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXZ50187.1 - 0.0088 16.4 0.1 0.023 15.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 tRNA-synt_2c PF01411.19 KXZ50188.1 - 2.3e-143 478.6 0.0 2.6e-129 432.3 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (A) DHHA1 PF02272.19 KXZ50188.1 - 2.1e-23 83.2 9.2 4.5e-23 82.2 9.2 1.6 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 KXZ50188.1 - 2.5e-19 69.1 0.3 5.1e-19 68.1 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF4140 PF13600.6 KXZ50188.1 - 0.048 14.1 0.3 0.13 12.7 0.3 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.11 KXZ50189.1 - 0.012 15.8 21.5 0.012 15.8 21.5 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Spc24 PF08286.11 KXZ50189.1 - 0.45 10.8 25.8 2.4 8.4 1.8 4.5 2 1 3 5 5 5 0 Spc24 subunit of Ndc80 AAA_13 PF13166.6 KXZ50189.1 - 0.56 8.8 21.7 0.92 8.1 9.5 2.2 1 1 2 3 3 3 0 AAA domain DUF4201 PF13870.6 KXZ50189.1 - 0.63 9.8 25.6 0.36 10.6 11.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) YabA PF06156.13 KXZ50189.1 - 1 10.1 22.2 0.59 10.8 2.6 4.0 2 1 2 4 4 4 0 Initiation control protein YabA Spc7 PF08317.11 KXZ50189.1 - 1.4 7.7 37.5 0.042 12.7 14.6 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KXZ50189.1 - 1.7 9.1 4.2 42 4.6 0.0 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Csm1_N PF18504.1 KXZ50189.1 - 3.3 8.1 29.2 2.2 8.7 7.5 5.4 3 2 2 5 5 5 0 Csm1 N-terminal domain NAPRTase_C PF17956.1 KXZ50189.1 - 3.5 8.1 7.8 0.39 11.1 0.3 2.5 1 1 1 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF1664 PF07889.12 KXZ50189.1 - 5.4 7.1 18.3 0.043 13.8 2.3 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.21 KXZ50189.1 - 7.7 6.0 36.7 0.018 14.7 9.5 3.0 1 1 1 3 3 3 0 Intermediate filament protein RBD-FIP PF09457.10 KXZ50189.1 - 9.4 6.2 10.0 0.48 10.4 1.8 2.8 3 0 0 3 3 3 0 FIP domain WD40 PF00400.32 KXZ50190.1 - 2.2e-54 180.2 20.4 2.2e-09 37.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ50190.1 - 4.4e-22 78.2 0.0 5.7e-05 23.3 0.0 6.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXZ50190.1 - 4.2e-12 45.5 3.8 0.0075 15.0 0.0 5.0 2 2 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KXZ50190.1 - 5.2e-08 33.0 0.0 0.0087 16.0 0.0 3.3 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXZ50190.1 - 3.4e-06 26.2 0.5 0.019 14.0 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXZ50190.1 - 0.0011 18.3 0.0 0.056 12.8 0.0 3.1 3 1 0 4 4 4 1 WD40-like domain DUF5046 PF16465.5 KXZ50190.1 - 0.0018 17.8 0.0 0.072 12.5 0.0 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF5046) Coatomer_WDAD PF04053.14 KXZ50190.1 - 0.0028 16.8 0.0 1.1 8.2 0.0 2.8 2 1 0 2 2 2 2 Coatomer WD associated region Frtz PF11768.8 KXZ50190.1 - 0.066 11.5 0.0 2.5 6.3 0.0 2.6 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz CRCB PF02537.15 KXZ50191.1 - 6.5e-21 74.4 23.1 1.3e-11 44.6 6.6 2.8 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Glyco_transf_90 PF05686.12 KXZ50192.1 - 6.6e-11 41.7 3.0 1.9e-10 40.2 3.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXZ50192.1 - 0.09 13.2 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Nudix_hydro PF18290.1 KXZ50193.1 - 4e-28 97.2 0.0 6.4e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 KXZ50193.1 - 2e-19 69.9 0.4 2.9e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 NUDIX domain Nif11 PF07862.11 KXZ50193.1 - 0.62 10.4 2.7 4.9 7.5 0.1 2.7 3 0 0 3 3 3 0 Nif11 domain cNMP_binding PF00027.29 KXZ50194.1 - 1.6e-20 73.0 0.1 2.6e-07 30.6 0.0 3.9 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain DNA_binding_1 PF01035.20 KXZ50195.1 - 1.4e-26 92.4 0.0 1.9e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF948 PF06103.11 KXZ50196.1 - 0.004 17.4 0.6 0.059 13.6 0.1 2.9 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KXZ50196.1 - 0.015 14.2 13.9 0.64 8.8 1.6 3.2 3 1 0 3 3 3 0 Spc7 kinetochore protein CobU PF02283.16 KXZ50196.1 - 0.024 14.2 1.1 0.061 12.9 1.1 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase KLRAQ PF10205.9 KXZ50196.1 - 0.18 12.0 7.9 0.27 11.5 1.2 2.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein SKA2 PF16740.5 KXZ50196.1 - 0.6 9.9 15.0 1.2 8.9 0.8 4.3 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 EzrA PF06160.12 KXZ50196.1 - 1.2 7.2 9.8 1.4 7.0 0.5 2.3 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 KXZ50196.1 - 1.2 8.4 23.9 1.1 8.6 4.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 KXZ50196.1 - 1.7 9.3 20.4 0.34 11.6 0.7 4.7 4 0 0 4 4 4 0 SlyX Laminin_II PF06009.12 KXZ50196.1 - 1.7 8.6 8.5 1.9 8.5 0.2 3.2 3 0 0 3 3 3 0 Laminin Domain II Prefoldin_2 PF01920.20 KXZ50196.1 - 2.2 8.3 6.4 16 5.5 0.8 3.7 3 1 1 4 4 4 0 Prefoldin subunit HalX PF08663.10 KXZ50196.1 - 3.2 8.1 17.8 0.66 10.3 4.7 4.8 5 0 0 5 5 5 0 HalX domain AAA_13 PF13166.6 KXZ50196.1 - 3.9 6.0 10.8 10 4.6 10.8 1.6 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.9 KXZ50196.1 - 4.9 6.1 14.7 0.041 13.0 2.0 2.6 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4404 PF14357.6 KXZ50196.1 - 9.8 6.9 16.2 12 6.6 0.3 4.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4404) SAGA-Tad1 PF12767.7 KXZ50197.1 - 0.2 11.4 5.9 0.25 11.0 5.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4407 PF14362.6 KXZ50197.1 - 0.22 10.9 12.3 0.24 10.7 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VSG_B PF13206.6 KXZ50197.1 - 0.31 10.2 13.4 0.5 9.6 13.4 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain AAA_11 PF13086.6 KXZ50197.1 - 0.84 9.4 9.6 1.1 9.0 9.6 1.2 1 0 0 1 1 1 0 AAA domain Nop53 PF07767.11 KXZ50197.1 - 1.6 8.1 24.9 2 7.7 24.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2828 PF11443.8 KXZ50197.1 - 1.6 6.7 9.0 2 6.4 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Atg14 PF10186.9 KXZ50197.1 - 1.6 7.7 7.3 2.1 7.4 7.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_S64 PF08192.11 KXZ50197.1 - 1.7 7.0 4.0 2.3 6.6 4.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 KXZ50197.1 - 1.9 7.1 9.8 2.1 7.1 9.8 1.2 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.20 KXZ50197.1 - 2.3 6.3 13.2 2.6 6.1 13.2 1.1 1 0 0 1 1 1 0 Hsp70 protein RR_TM4-6 PF06459.12 KXZ50197.1 - 3 7.6 18.0 3.9 7.2 18.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 KXZ50197.1 - 3.2 6.4 8.2 4.6 5.9 8.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5401 PF17380.2 KXZ50197.1 - 4 5.4 23.1 5.3 5.0 23.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4554 PF15091.6 KXZ50197.1 - 4.4 6.1 7.9 6.7 5.5 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Bromodomain PF00439.25 KXZ50198.1 - 2.2e-23 82.1 0.0 4.7e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 KXZ50198.1 - 2.4e-19 69.3 1.2 4.4e-19 68.4 1.2 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Vps52 PF04129.12 KXZ50200.1 - 5.6e-91 305.8 0.0 7e-91 305.5 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KXZ50200.1 - 3.8e-10 38.8 8.3 6.7e-08 31.4 8.3 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec3 Sec34 PF04136.15 KXZ50200.1 - 0.013 15.4 2.5 0.055 13.4 1.0 2.2 1 1 1 2 2 2 0 Sec34-like family DUF3050 PF11251.8 KXZ50200.1 - 0.076 12.6 0.6 0.64 9.6 0.0 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF3050) Allexi_40kDa PF05549.11 KXZ50200.1 - 0.13 11.8 2.3 0.35 10.3 0.2 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein COG2 PF06148.11 KXZ50200.1 - 0.5 10.5 7.1 3.7 7.7 1.7 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PALP PF00291.25 KXZ50203.1 - 1.4e-47 162.5 0.8 4.7e-47 160.8 0.8 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 KXZ50204.1 - 1.1e-29 103.5 33.2 4.5e-16 58.7 9.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXZ50204.1 - 0.033 12.5 0.1 0.033 12.5 0.1 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KXZ50204.1 - 0.044 12.3 21.8 0.11 11.0 8.6 2.4 2 0 0 2 2 2 0 MFS/sugar transport protein MFS_1_like PF12832.7 KXZ50204.1 - 0.063 12.1 13.8 98 1.6 13.8 2.7 1 1 0 1 1 1 0 MFS_1 like family YlaC PF10777.9 KXZ50204.1 - 6.7 6.5 5.3 1.5 8.7 1.3 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC CLTH PF10607.9 KXZ50205.1 - 4.1e-25 88.4 0.0 7.5e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KXZ50205.1 - 1.5e-06 28.1 2.4 3.8e-06 26.8 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ50205.1 - 5.9e-05 22.9 1.2 5.9e-05 22.9 1.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXZ50205.1 - 0.0014 18.9 2.5 0.0041 17.4 2.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXZ50205.1 - 0.002 17.9 2.9 0.0058 16.5 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ50205.1 - 0.0034 17.2 1.4 0.0092 15.8 1.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXZ50205.1 - 0.019 15.1 2.5 0.074 13.2 2.5 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXZ50205.1 - 0.025 14.4 3.0 0.025 14.4 3.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ50205.1 - 0.032 14.1 2.8 0.078 12.8 2.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 UBA PF00627.31 KXZ50210.1 - 3.9e-27 93.7 7.8 4.5e-13 48.8 0.5 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KXZ50210.1 - 1.7e-21 75.7 3.3 2.7e-21 75.0 3.3 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KXZ50210.1 - 2.4e-11 43.2 0.1 3.3e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KXZ50210.1 - 7e-05 23.3 0.0 0.00012 22.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KXZ50210.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KXZ50210.1 - 0.00022 21.3 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CCDC53 PF10152.9 KXZ50210.1 - 5.8 7.3 5.7 10 6.6 2.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex She9_MDM33 PF05546.11 KXZ50211.1 - 9.5e-25 87.6 0.0 7.3e-17 61.8 0.0 2.3 2 0 0 2 2 2 2 She9 / Mdm33 family Baculo_PEP_C PF04513.12 KXZ50211.1 - 0.068 13.2 0.0 6.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Coatomer_WDAD PF04053.14 KXZ50212.1 - 0.6 9.1 0.9 1.6 7.7 0.1 1.8 2 0 0 2 2 2 0 Coatomer WD associated region NUDIX PF00293.28 KXZ50213.1 - 2.9e-16 59.7 0.5 4e-16 59.3 0.5 1.2 1 0 0 1 1 1 1 NUDIX domain Tmemb_14 PF03647.13 KXZ50213.1 - 5.7e-13 49.4 6.9 8.9e-13 48.8 6.9 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C HTH_AsnC-type PF13404.6 KXZ50213.1 - 0.018 14.9 1.0 0.047 13.5 0.6 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF1979 PF09322.10 KXZ50213.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) Ank PF00023.30 KXZ50214.1 - 0.006 17.0 0.5 2 9.0 0.1 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXZ50214.1 - 0.008 16.6 0.5 0.63 10.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXZ50214.1 - 0.048 14.2 0.0 0.26 11.9 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ50214.1 - 0.16 12.6 0.2 7.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Hydrolase_4 PF12146.8 KXZ50215.1 - 2e-06 27.3 0.1 7e-06 25.5 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DAGAT PF03982.13 KXZ50215.1 - 2.2e-05 23.6 0.0 5.6e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KXZ50215.1 - 0.0003 20.4 0.1 0.026 14.1 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Methyltransf_2 PF00891.18 KXZ50216.1 - 5.5e-40 136.9 0.0 8.3e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXZ50216.1 - 2.8e-07 30.4 0.1 1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_11 PF08241.12 KXZ50216.1 - 6e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ50216.1 - 6e-05 23.7 0.0 0.00011 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ50216.1 - 0.00011 22.8 0.0 0.00023 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ50216.1 - 0.0002 21.0 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXZ50216.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NIR_SIR PF01077.22 KXZ50217.1 - 2.3e-62 209.2 0.0 3.4e-48 163.2 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KXZ50217.1 - 8.2e-31 105.7 0.2 4.1e-14 52.2 0.1 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain TPP_enzyme_M PF00205.22 KXZ50217.1 - 0.13 12.0 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Phos_pyr_kin PF08543.12 KXZ50218.1 - 2.8e-82 275.8 2.5 6.6e-47 160.0 0.0 2.8 3 0 0 3 3 3 2 Phosphomethylpyrimidine kinase TMP-TENI PF02581.17 KXZ50218.1 - 1.6e-60 203.6 3.3 3.6e-60 202.4 3.3 1.7 1 0 0 1 1 1 1 Thiamine monophosphate synthase TENA_THI-4 PF03070.16 KXZ50218.1 - 5.7e-21 75.3 0.1 9.3e-14 51.7 0.1 2.4 2 0 0 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.24 KXZ50218.1 - 0.00046 19.6 0.1 0.00046 19.6 0.1 2.4 3 1 0 3 3 3 1 pfkB family carbohydrate kinase HAD PF12710.7 KXZ50218.1 - 0.0047 17.3 5.4 0.023 15.1 0.6 4.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ50218.1 - 0.16 12.2 8.0 0.7 10.1 2.2 4.0 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Mur_ligase PF01225.25 KXZ50218.1 - 1.7 9.0 4.9 3.5 8.0 0.2 3.0 2 0 0 2 2 2 0 Mur ligase family, catalytic domain PP2C PF00481.21 KXZ50219.1 - 5.9e-35 121.1 0.0 2.4e-34 119.1 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2880 PF11082.8 KXZ50219.1 - 0.074 13.4 1.0 0.18 12.1 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) DOT1 PF08123.13 KXZ50220.1 - 1.5e-05 24.6 0.1 2.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Guanylate_cyc PF00211.20 KXZ50223.1 - 0.0049 16.5 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SBP_bac_8 PF13416.6 KXZ50223.1 - 0.21 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Peptidase_M3 PF01432.20 KXZ50224.1 - 0.00052 19.4 0.0 6.2 6.0 0.1 3.9 4 0 0 4 4 4 3 Peptidase family M3 Pkinase PF00069.25 KXZ50225.1 - 2.1e-35 122.4 0.0 2.8e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50225.1 - 6.7e-27 94.4 0.0 1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50225.1 - 8.8e-05 21.9 0.0 0.00051 19.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ50225.1 - 0.0034 16.2 0.0 0.0046 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ50225.1 - 0.037 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLAC8 PF04749.17 KXZ50226.1 - 8.8e-17 61.9 10.3 1e-16 61.7 10.3 1.1 1 0 0 1 1 1 1 PLAC8 family DUF2226 PF09987.9 KXZ50226.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) C2 PF00168.30 KXZ50227.1 - 6.9e-08 32.7 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain MMM1 PF10296.9 KXZ50227.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 PhoD PF09423.10 KXZ50228.1 - 5.8e-07 28.9 0.1 2e-05 23.8 0.1 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase DUF4581 PF15167.6 KXZ50228.1 - 0.049 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) Rhodanese PF00581.20 KXZ50229.1 - 2.1e-22 79.7 0.0 2.5e-14 53.7 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Peptidase_M20 PF01546.28 KXZ50230.1 - 1.6e-10 41.0 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXZ50230.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 M20_dimer PF07687.14 KXZ50230.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Pkinase_Tyr PF07714.17 KXZ50231.1 - 4.5e-46 157.2 0.0 1.1e-45 156.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50231.1 - 3.9e-40 137.9 0.0 9.2e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ50231.1 - 0.056 13.4 0.0 0.056 13.4 0.0 9.1 3 1 3 6 6 6 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ50231.1 - 0.079 11.9 0.0 0.21 10.5 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Pox_A_type_inc PF04508.12 KXZ50231.1 - 2.1 8.3 8.5 2.2 8.3 0.1 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Chloroa_b-bind PF00504.21 KXZ50232.1 - 1e-42 146.4 0.4 1.9e-42 145.5 0.4 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein H_kinase_N PF12282.8 KXZ50232.1 - 0.079 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal transduction histidine kinase MFS_1 PF07690.16 KXZ50233.1 - 5.1e-09 35.5 23.2 5.1e-09 35.5 23.2 2.8 4 0 0 4 4 4 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ50233.1 - 9.6 4.9 14.6 0.054 12.4 5.1 1.9 2 1 1 3 3 3 0 Sugar (and other) transporter Glucos_trans_II PF14264.6 KXZ50234.1 - 0.0018 17.7 1.5 0.0029 17.0 1.5 1.3 1 0 0 1 1 1 1 Glucosyl transferase GtrII FAST_1 PF06743.15 KXZ50235.1 - 4.9e-06 26.4 0.0 1.4 8.9 0.0 4.3 2 1 2 4 4 4 4 FAST kinase-like protein, subdomain 1 Spc7 PF08317.11 KXZ50236.1 - 6.9e-05 21.9 29.5 0.00073 18.5 1.6 3.9 4 0 0 4 4 4 2 Spc7 kinetochore protein Shugoshin_N PF07558.11 KXZ50236.1 - 0.0004 20.2 8.2 0.0021 17.9 0.1 3.3 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region BicD PF09730.9 KXZ50236.1 - 0.00089 17.8 0.7 0.00089 17.8 0.7 3.6 4 0 0 4 4 4 2 Microtubule-associated protein Bicaudal-D DUF4715 PF15835.5 KXZ50236.1 - 0.0064 16.6 2.2 0.031 14.3 0.0 3.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4715) Fez1 PF06818.15 KXZ50236.1 - 0.016 15.7 23.7 0.87 10.0 5.0 4.3 3 1 0 4 4 4 0 Fez1 Cnn_1N PF07989.11 KXZ50236.1 - 0.017 15.3 0.1 0.017 15.3 0.1 4.5 4 1 0 4 4 4 0 Centrosomin N-terminal motif 1 SLATT_4 PF18186.1 KXZ50236.1 - 0.036 13.7 3.8 0.071 12.7 0.4 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Leu_zip PF15294.6 KXZ50236.1 - 0.043 13.3 8.4 0.065 12.7 0.1 3.3 4 0 0 4 4 4 0 Leucine zipper COG2 PF06148.11 KXZ50236.1 - 0.046 13.8 0.3 0.046 13.8 0.3 4.6 4 1 1 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1635 PF07795.11 KXZ50236.1 - 0.18 11.6 10.4 3 7.7 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) TSC22 PF01166.18 KXZ50236.1 - 0.24 11.7 0.0 0.24 11.7 0.0 4.3 4 1 1 5 5 5 0 TSC-22/dip/bun family Atg14 PF10186.9 KXZ50236.1 - 0.31 10.1 19.2 0.13 11.3 2.9 3.5 3 1 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2353 PF09789.9 KXZ50236.1 - 0.4 10.0 12.1 0.04 13.3 0.7 3.2 3 1 1 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) bZIP_1 PF00170.21 KXZ50236.1 - 0.57 10.3 0.0 0.57 10.3 0.0 4.3 5 0 0 5 5 3 0 bZIP transcription factor YabA PF06156.13 KXZ50236.1 - 1.1 9.9 0.0 1.1 9.9 0.0 4.4 4 2 1 5 5 5 0 Initiation control protein YabA Rootletin PF15035.6 KXZ50236.1 - 1.2 9.2 27.8 0.078 13.0 2.2 4.0 3 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Herpes_UL6 PF01763.16 KXZ50236.1 - 1.2 7.6 4.9 0.28 9.7 0.1 2.3 3 0 0 3 3 3 0 Herpesvirus UL6 like ATG16 PF08614.11 KXZ50236.1 - 2.4 8.4 50.7 1.2 9.3 1.7 5.4 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 KXZ50236.1 - 3.3 5.8 20.7 0.37 8.9 1.3 3.6 4 0 0 4 4 4 0 HOOK protein Troponin PF00992.20 KXZ50236.1 - 3.3 8.0 22.8 9.1 6.6 1.9 4.9 5 0 0 5 5 4 0 Troponin TMF_TATA_bd PF12325.8 KXZ50236.1 - 3.6 7.8 32.4 2.2 8.5 0.9 5.7 4 2 1 5 5 5 0 TATA element modulatory factor 1 TATA binding GIT_CC PF16559.5 KXZ50236.1 - 4 7.4 10.1 5 7.1 0.0 3.2 4 0 0 4 4 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor BBS2_C PF14782.6 KXZ50236.1 - 4.4 6.0 6.3 1 8.0 0.3 2.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal DUF4140 PF13600.6 KXZ50236.1 - 4.7 7.7 48.4 2.4 8.7 10.0 6.9 5 2 1 6 6 6 0 N-terminal domain of unknown function (DUF4140) WD40_alt PF14077.6 KXZ50236.1 - 7.9 6.4 5.3 7.3 6.5 0.2 3.3 4 0 0 4 4 4 0 Alternative WD40 repeat motif FlaC_arch PF05377.11 KXZ50236.1 - 8 6.9 8.8 52 4.3 0.0 4.4 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) Aa_trans PF01490.18 KXZ50238.1 - 7.5e-25 87.5 2.8 1e-24 87.1 2.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 KXZ50239.1 - 6.8e-26 91.2 0.0 6.3e-10 38.9 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50239.1 - 7.3e-26 91.0 0.0 1.1e-10 41.3 0.0 4.0 4 0 0 4 4 4 4 Protein tyrosine kinase DUF347 PF03988.12 KXZ50239.1 - 1.2 9.3 4.1 0.57 10.4 0.3 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Nucleotid_trans PF03407.16 KXZ50240.1 - 1.5e-45 155.8 1.1 1.8e-45 155.5 1.1 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase WD40 PF00400.32 KXZ50241.1 - 2.1e-08 34.6 0.0 0.65 11.0 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat MID_MedPIWI PF18296.1 KXZ50241.1 - 0.034 13.9 0.9 0.052 13.3 0.9 1.2 1 0 0 1 1 1 0 MID domain of medPIWI LRR_6 PF13516.6 KXZ50242.1 - 0.00027 20.7 0.8 0.0015 18.4 0.2 2.5 3 0 0 3 3 3 1 Leucine Rich repeat EF-hand_6 PF13405.6 KXZ50242.1 - 0.021 14.7 0.0 11 6.3 0.0 4.1 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.32 KXZ50242.1 - 0.033 13.8 0.0 31 4.4 0.0 4.1 4 0 0 4 4 4 0 EF hand Phospholip_B PF04916.13 KXZ50243.1 - 5.3e-124 414.7 0.5 1.4e-99 334.1 0.5 3.0 3 0 0 3 3 3 3 Phospholipase B Methyltransf_11 PF08241.12 KXZ50245.1 - 2.9e-21 75.9 0.0 6.1e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ50245.1 - 4e-18 65.9 0.0 7.1e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ50245.1 - 6.2e-14 52.2 0.0 8.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ50245.1 - 4.7e-13 49.2 0.0 6e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXZ50245.1 - 2.2e-11 43.6 0.0 3.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KXZ50245.1 - 1.3e-09 38.7 0.0 1.9e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ50245.1 - 4.1e-06 26.3 0.0 8.6e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KXZ50245.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KXZ50245.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 KXZ50245.1 - 0.25 11.3 0.0 0.4 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PNP_UDP_1 PF01048.20 KXZ50246.1 - 0.031 13.5 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily SpoVS PF04232.12 KXZ50246.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) EF-hand_1 PF00036.32 KXZ50247.1 - 9.5e-19 65.5 3.0 0.00016 21.0 0.0 4.5 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KXZ50247.1 - 2.7e-15 54.9 4.9 0.0046 16.8 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXZ50247.1 - 2.3e-13 48.9 2.9 0.0024 17.3 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KXZ50247.1 - 5.9e-13 49.1 7.2 3.2e-07 30.7 0.5 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KXZ50247.1 - 3.5e-07 30.0 7.3 0.00015 21.5 0.2 3.9 2 1 1 4 4 4 3 EF-hand domain pair Caleosin PF05042.13 KXZ50247.1 - 0.022 14.7 0.1 8.9 6.2 0.0 3.0 2 1 1 3 3 3 0 Caleosin related protein SPX PF03105.19 KXZ50248.1 - 3e-13 50.5 0.2 8.9e-06 25.9 0.0 3.4 2 1 1 3 3 3 3 SPX domain PS-DH PF14765.6 KXZ50249.1 - 3.8e-06 26.4 0.0 4.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Arf PF00025.21 KXZ50250.1 - 2.2e-62 209.6 0.0 2.5e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXZ50250.1 - 3.5e-09 36.4 0.0 5.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KXZ50250.1 - 9.5e-09 35.5 0.0 2e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXZ50250.1 - 1.1e-08 34.7 0.1 2.8e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXZ50250.1 - 4.1e-07 29.8 0.0 4.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KXZ50250.1 - 6.2e-07 29.5 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXZ50250.1 - 0.001 18.5 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KXZ50250.1 - 0.0089 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Antibiotic_NAT PF02522.14 KXZ50250.1 - 0.096 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase Pkinase_Tyr PF07714.17 KXZ50251.1 - 6.5e-45 153.4 0.0 9.3e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50251.1 - 1.8e-44 152.1 0.0 2.7e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ50251.1 - 0.0056 15.5 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ50251.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KXZ50251.1 - 0.026 14.5 1.9 0.029 14.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABATE PF07336.11 KXZ50251.1 - 9.9 6.8 15.9 0.77 10.4 4.1 2.9 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Exostosin PF03016.15 KXZ50252.1 - 7.6e-25 87.7 0.0 3.2e-16 59.4 0.0 2.4 2 1 0 2 2 2 2 Exostosin family WD40 PF00400.32 KXZ50254.1 - 1.4e-06 28.9 15.4 0.07 14.0 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Herpes_LMP1 PF05297.11 KXZ50255.1 - 0.92 8.6 3.6 1.4 8.1 3.6 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DHHC PF01529.20 KXZ50255.1 - 1.3 9.1 4.3 2.7 8.1 2.0 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase PhoR PF11808.8 KXZ50256.1 - 0.13 12.7 8.0 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Myelin_PLP PF01275.19 KXZ50256.1 - 0.57 10.0 7.3 2.4 8.0 7.3 1.9 1 1 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Rhodanese PF00581.20 KXZ50257.1 - 1.3e-06 28.8 0.0 7.5e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Rhodanese-like domain Ank_2 PF12796.7 KXZ50258.1 - 9.5e-34 115.8 1.8 4.1e-12 46.5 0.1 4.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ50258.1 - 8.5e-25 86.5 14.5 2e-06 27.9 0.0 7.1 2 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ50258.1 - 1.5e-24 86.1 3.8 3.7e-07 30.6 0.1 6.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50258.1 - 2.2e-22 76.7 7.5 0.04 14.5 0.0 9.0 8 1 1 9 9 9 6 Ankyrin repeat Ank PF00023.30 KXZ50258.1 - 1.9e-15 56.5 19.8 0.23 12.0 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat FAD_binding_3 PF01494.19 KXZ50259.1 - 1.5e-13 50.8 4.3 8.2e-09 35.2 0.5 3.3 4 0 0 4 4 4 3 FAD binding domain SE PF08491.10 KXZ50259.1 - 0.016 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase EamA PF00892.20 KXZ50260.1 - 9.6e-10 38.8 23.0 1.6e-05 25.1 3.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KXZ50260.1 - 4e-09 36.2 9.8 9.2e-05 21.9 3.6 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family PEP-CTERM PF07589.11 KXZ50260.1 - 0.88 9.7 5.3 1.2 9.3 0.3 3.2 2 0 0 2 2 2 0 PEP-CTERM motif ELP6 PF09807.9 KXZ50261.1 - 6.6e-09 35.5 0.0 1.3e-06 28.1 0.0 2.0 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 KXZ50261.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 KaiC MEDS PF14417.6 KXZ50261.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.6 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain MPC PF03650.13 KXZ50264.1 - 6e-20 71.4 0.0 6.5e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers WD40 PF00400.32 KXZ50265.1 - 1.4e-45 152.4 36.3 0.00061 20.5 0.0 19.0 19 0 0 19 19 19 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ50265.1 - 2.8e-29 101.2 2.6 0.0026 18.0 0.0 11.9 4 4 10 14 14 14 7 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans PF00520.31 KXZ50265.1 - 2e-13 50.2 26.3 3.3e-13 49.4 25.3 1.7 2 0 0 2 2 2 1 Ion transport protein Cytochrom_D1 PF02239.16 KXZ50265.1 - 3.7e-05 22.4 0.8 0.69 8.4 0.0 4.9 3 3 2 5 5 5 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KXZ50265.1 - 0.00021 20.4 11.3 4.4 6.2 0.0 7.8 7 3 3 10 10 10 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PKD_channel PF08016.12 KXZ50265.1 - 0.00069 18.4 19.1 0.26 9.9 19.1 2.2 1 1 0 1 1 1 1 Polycystin cation channel Nbas_N PF15492.6 KXZ50265.1 - 0.00074 18.9 0.1 15 4.8 0.0 5.1 5 0 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Ank_4 PF13637.6 KXZ50265.1 - 0.0043 17.6 0.0 0.15 12.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ50265.1 - 0.0097 16.5 0.0 0.12 13.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Hira PF07569.11 KXZ50265.1 - 0.034 13.9 5.9 16 5.1 0.0 5.8 8 1 0 8 8 8 0 TUP1-like enhancer of split eIF2A PF08662.11 KXZ50265.1 - 0.041 13.8 0.0 6.6 6.6 0.0 3.9 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A Ank_3 PF13606.6 KXZ50265.1 - 0.095 13.3 0.0 1.8 9.4 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 KXZ50265.1 - 0.14 12.5 0.1 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) WD40_like PF17005.5 KXZ50265.1 - 0.17 11.2 0.0 1.2 8.3 0.0 2.2 2 1 1 3 3 3 0 WD40-like domain WD40_3 PF15911.5 KXZ50265.1 - 0.18 11.8 0.7 13 5.9 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat Peptidase_C2 PF00648.21 KXZ50266.1 - 7.3e-17 61.3 0.1 8.2e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Pkinase_Tyr PF07714.17 KXZ50267.1 - 4.5e-37 127.7 0.0 5.5e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50267.1 - 1.6e-32 112.9 0.0 2e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ50267.1 - 0.00064 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ50267.1 - 0.0019 17.6 0.1 0.0045 16.4 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ50267.1 - 0.0045 16.3 0.0 0.0088 15.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ50267.1 - 0.052 12.3 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KXZ50267.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 KXZ50268.1 - 6.2e-47 160.2 0.0 9.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50268.1 - 4.2e-25 88.5 0.0 5.9e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50268.1 - 2e-05 24.1 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ50268.1 - 0.00037 19.4 0.0 0.00051 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ50268.1 - 0.00082 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ50268.1 - 0.0053 16.7 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXZ50268.1 - 0.0095 15.5 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.25 KXZ50269.1 - 7e-50 169.8 0.0 9.8e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50269.1 - 3.1e-27 95.5 0.0 4.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50269.1 - 8.1e-06 25.4 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ50269.1 - 2.5e-05 23.2 0.0 3.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ50269.1 - 0.0084 16.1 0.3 0.014 15.3 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ50269.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Shufflon_N PF04917.12 KXZ50269.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Ion_trans PF00520.31 KXZ50270.1 - 2.8e-25 89.0 12.8 3.8e-25 88.6 12.8 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KXZ50270.1 - 2e-18 66.2 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PHO4 PF01384.20 KXZ50270.1 - 0.094 11.7 0.2 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 Phosphate transporter family Pkinase PF00069.25 KXZ50271.1 - 3.6e-62 210.1 0.0 5.4e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50271.1 - 1.8e-35 122.5 0.0 1.5e-33 116.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_18 PF00704.28 KXZ50271.1 - 9e-28 97.9 0.0 1.5e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 APH PF01636.23 KXZ50271.1 - 0.0032 17.4 0.1 0.0032 17.4 0.1 3.3 4 1 0 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ50271.1 - 0.051 12.9 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SBP PF03110.14 KXZ50272.1 - 5.2e-26 90.8 2.1 9.6e-26 89.9 2.1 1.5 1 0 0 1 1 1 1 SBP domain LTD PF00932.19 KXZ50273.1 - 2.6e-26 92.2 0.0 1e-15 58.1 0.0 2.4 2 0 0 2 2 2 2 Lamin Tail Domain CotH PF08757.11 KXZ50273.1 - 7.2e-20 71.7 0.0 2.9e-13 50.0 0.0 3.1 2 1 0 2 2 2 2 CotH kinase protein Gln-synt_C PF00120.24 KXZ50274.1 - 4.8e-15 55.4 0.0 1.9e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXZ50274.1 - 1e-11 44.4 0.0 1.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ABC_tran PF00005.27 KXZ50275.1 - 1.8e-25 90.1 0.0 3.5e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KXZ50275.1 - 0.005 17.4 0.1 0.0082 16.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KXZ50275.1 - 0.0074 16.1 1.7 2.4 7.9 0.2 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXZ50275.1 - 0.018 14.9 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 KXZ50275.1 - 0.024 14.6 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KXZ50275.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Flu_PB2 PF00604.17 KXZ50275.1 - 0.34 8.8 0.0 0.52 8.2 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 SbcCD_C PF13558.6 KXZ50275.1 - 0.39 11.0 8.7 5.7 7.2 0.1 3.9 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit Asn_synthase PF00733.21 KXZ50277.1 - 4.3e-95 319.4 0.6 4.6e-54 184.4 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXZ50277.1 - 3.2e-36 123.9 0.0 5e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXZ50277.1 - 1.4e-24 86.8 0.0 3.9e-24 85.3 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXZ50277.1 - 8.3e-09 35.2 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXZ50277.1 - 0.036 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Peptidase_M1 PF01433.20 KXZ50279.1 - 1.4e-59 201.3 0.0 7.3e-55 185.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M1 domain ERAP1_C PF11838.8 KXZ50279.1 - 1.2e-35 123.6 0.2 1.9e-17 63.8 0.0 2.2 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KXZ50279.1 - 1.4e-28 100.3 0.0 3.3e-28 99.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2048 PF09752.9 KXZ50280.1 - 2.1e-66 224.4 0.0 2.2e-52 178.3 0.0 3.6 2 1 1 3 3 3 3 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 KXZ50280.1 - 0.11 12.2 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXZ50280.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Fez1 PF06818.15 KXZ50281.1 - 7.3e-05 23.3 6.4 7.3e-05 23.3 6.4 14.2 4 4 7 13 13 13 3 Fez1 Tropomyosin_1 PF12718.7 KXZ50281.1 - 0.00039 20.6 5.2 0.00039 20.6 5.2 16.5 6 5 7 15 15 15 1 Tropomyosin like GRIP PF01465.20 KXZ50281.1 - 0.00087 19.2 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 GRIP domain HAP1_N PF04849.13 KXZ50281.1 - 0.0014 17.9 11.2 0.0014 17.9 11.2 11.6 6 4 6 12 12 12 2 HAP1 N-terminal conserved region DPBB_1 PF03330.18 KXZ50284.1 - 0.0028 17.9 0.3 3 8.2 0.0 2.8 3 0 0 3 3 3 2 Lytic transglycolase C2 PF00168.30 KXZ50285.1 - 9.9e-18 64.3 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain Ank_4 PF13637.6 KXZ50286.1 - 2.9e-10 40.5 0.3 1.3 9.7 0.5 5.8 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ50286.1 - 8.4e-09 35.9 0.0 0.29 11.7 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ50286.1 - 5.6e-05 23.2 0.5 39 5.3 0.0 7.0 8 0 0 8 8 8 1 Ankyrin repeat Pkinase PF00069.25 KXZ50287.1 - 1.8e-46 158.7 0.0 3.1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50287.1 - 1.9e-18 66.7 0.0 4.3e-18 65.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50289.1 - 7.1e-61 205.9 0.0 8.4e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50289.1 - 1.4e-32 113.0 0.0 1.8e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50289.1 - 0.028 13.8 0.0 0.13 11.5 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KXZ50289.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ50290.1 - 3.5e-39 134.7 0.0 4.4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50290.1 - 1.5e-14 53.9 0.0 1.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ50290.1 - 0.047 12.5 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ESCRT-II PF05871.12 KXZ50291.1 - 9.8e-20 71.2 0.1 1.2e-19 70.9 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit GntR PF00392.21 KXZ50291.1 - 0.033 13.8 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 KXZ50291.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain ATP-synt_ab PF00006.25 KXZ50292.1 - 6.2e-67 225.4 0.0 1e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXZ50292.1 - 7.9e-13 48.7 1.5 1.3e-12 48.0 1.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain URO-D PF01208.17 KXZ50293.1 - 1.5e-114 382.8 0.0 1.9e-114 382.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Cellulase-like PF12876.7 KXZ50293.1 - 0.18 11.1 0.0 0.91 8.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-binding cellulase-like GTP_EFTU PF00009.27 KXZ50294.1 - 6.1e-69 231.5 0.1 9.4e-69 230.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXZ50294.1 - 5.4e-43 145.6 0.0 1.2e-42 144.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KXZ50294.1 - 4.2e-33 113.3 0.0 8e-33 112.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KXZ50294.1 - 3.8e-28 97.4 0.1 8.3e-28 96.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXZ50294.1 - 9.7e-17 61.1 0.5 7.8e-16 58.2 0.1 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXZ50294.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KXZ50294.1 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KXZ50294.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Pkinase_Tyr PF07714.17 KXZ50296.1 - 1.6e-22 80.1 0.0 9.8e-18 64.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50296.1 - 4.3e-11 42.7 0.0 6.4e-06 25.7 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain ParcG PF10274.9 KXZ50297.1 - 1.5e-80 269.6 0.0 2e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 KXZ50297.1 - 0.13 12.0 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 CBS PF00571.28 KXZ50299.1 - 6.5e-18 64.9 0.2 1.3e-06 28.7 0.1 4.4 4 0 0 4 4 4 4 CBS domain ABC2_membrane PF01061.24 KXZ50300.1 - 0.0036 16.8 10.5 0.0052 16.2 10.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KXZ50300.1 - 4.3 6.4 6.4 6 5.9 6.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Exostosin PF03016.15 KXZ50301.1 - 9.6e-32 110.4 0.0 3.7e-31 108.4 0.0 1.9 1 1 0 1 1 1 1 Exostosin family Indigoidine_A PF04227.12 KXZ50302.1 - 1.7e-132 441.2 3.4 1.9e-132 441.0 3.4 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein DUF4715 PF15835.5 KXZ50302.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) CENP-F_leu_zip PF10473.9 KXZ50303.1 - 0.0007 19.6 12.4 0.0007 19.6 12.4 7.5 7 2 0 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KXZ50303.1 - 1.2 9.2 27.6 2 8.5 0.9 7.8 7 3 2 9 9 9 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXZ50303.1 - 2.5 6.9 69.4 0.012 14.5 1.6 6.8 5 2 3 8 8 8 0 Spc7 kinetochore protein PseudoU_synth_2 PF00849.22 KXZ50305.1 - 2.5e-23 82.9 0.0 4.6e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Lipase_GDSL_2 PF13472.6 KXZ50306.1 - 0.00044 20.7 10.3 2.1 8.7 10.3 3.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXZ50306.1 - 0.00047 20.2 0.0 0.0016 18.4 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GDH_N PF12466.8 KXZ50306.1 - 0.2 11.9 1.9 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal Lipase_GDSL_2 PF13472.6 KXZ50307.1 - 0.013 15.9 1.1 0.15 12.4 1.1 2.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family zf-RING_2 PF13639.6 KXZ50309.1 - 9.1e-12 45.1 5.2 1.1e-11 44.8 5.2 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ50309.1 - 2e-07 30.7 5.7 2.7e-07 30.3 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ50309.1 - 6.6e-06 26.0 5.5 8.5e-06 25.6 5.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ50309.1 - 7.2e-06 25.8 5.3 1e-05 25.3 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXZ50309.1 - 8.6e-06 25.4 3.0 8.6e-06 25.4 3.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KXZ50309.1 - 9.4e-05 22.6 7.0 0.00024 21.3 7.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KXZ50309.1 - 0.0001 21.9 7.1 0.00017 21.1 7.1 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KXZ50309.1 - 0.00014 21.7 8.0 0.00019 21.2 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ50309.1 - 0.00015 21.7 3.6 0.00016 21.6 0.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXZ50309.1 - 0.00078 19.3 7.3 0.002 18.0 7.5 1.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXZ50309.1 - 0.0029 17.6 5.0 0.0042 17.1 5.0 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KXZ50309.1 - 0.0074 16.4 3.7 0.019 15.1 3.7 1.6 1 1 0 1 1 1 1 RING-variant domain Gon7 PF08738.10 KXZ50310.1 - 0.00031 20.8 5.5 0.15 12.2 0.5 2.3 2 0 0 2 2 2 2 Gon7 family Mt_ATP-synt_D PF05873.12 KXZ50310.1 - 0.0092 15.8 0.3 5.8 6.8 0.1 2.4 2 0 0 2 2 2 2 ATP synthase D chain, mitochondrial (ATP5H) RAC_head PF16717.5 KXZ50310.1 - 0.012 16.6 1.7 0.28 12.2 0.2 2.3 2 0 0 2 2 2 0 Ribosome-associated complex head domain DUF1967 PF09269.11 KXZ50310.1 - 0.22 11.5 1.6 7.4 6.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) HTH_51 PF18558.1 KXZ50310.1 - 0.23 11.3 1.7 5.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_C_13 PF16925.5 KXZ50310.1 - 1 9.3 6.6 4.5 7.3 0.8 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF834 PF05754.14 KXZ50310.1 - 1.4 9.0 8.0 1.5 8.9 1.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF834) TnpV PF14198.6 KXZ50310.1 - 2 8.5 7.9 9.5 6.3 1.1 2.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpV CorA PF01544.18 KXZ50314.1 - 9.5e-06 25.1 0.1 2.2e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EF-hand_8 PF13833.6 KXZ50314.1 - 6.7e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ50314.1 - 0.0065 16.0 0.1 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXZ50314.1 - 0.013 15.4 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KXZ50314.1 - 0.021 15.3 0.2 0.069 13.6 0.2 1.8 1 1 0 1 1 1 0 EF-hand domain pair DUF2207 PF09972.9 KXZ50314.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Frigida PF07899.11 KXZ50314.1 - 0.21 10.8 0.1 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Frigida-like protein Arm PF00514.23 KXZ50315.1 - 2.3e-22 78.3 9.4 3.1e-05 23.9 0.1 4.7 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXZ50315.1 - 0.0013 19.2 15.0 0.33 11.5 0.5 5.4 5 1 0 5 5 5 2 HEAT-like repeat Adaptin_N PF01602.20 KXZ50315.1 - 0.0048 15.5 0.4 1.9 7.0 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 KXZ50315.1 - 0.043 14.2 11.9 0.057 13.8 3.9 3.9 1 1 3 4 4 4 0 HEAT repeats Arm_2 PF04826.13 KXZ50315.1 - 0.048 13.1 0.1 7.1 6.0 0.0 3.1 2 1 1 3 3 3 0 Armadillo-like HEAT PF02985.22 KXZ50315.1 - 1.9 9.0 12.2 2.1 8.8 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat GCP_C_terminal PF04130.13 KXZ50316.1 - 2.7e-14 53.3 0.0 3.1e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Guanylate_cyc PF00211.20 KXZ50317.1 - 2.6e-38 131.5 0.0 9e-28 97.1 0.0 2.2 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.13 KXZ50317.1 - 2.5e-09 37.4 0.0 5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 CHASE domain PDEase_I PF00233.19 KXZ50318.1 - 3.3e-71 239.8 0.0 4.7e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 KXZ50318.1 - 4.2e-05 23.6 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 CHASE domain PDEase_I PF00233.19 KXZ50319.1 - 3.2e-71 239.8 0.0 4.5e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CHASE PF03924.13 KXZ50319.1 - 6.4e-05 23.0 0.0 0.00017 21.6 0.0 1.6 1 1 0 1 1 1 1 CHASE domain tRNA-synt_1b PF00579.25 KXZ50321.1 - 1.2e-09 37.9 0.0 1.4e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Iso_dh PF00180.20 KXZ50322.1 - 6.1e-105 351.2 0.0 7e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 KXZ50322.1 - 0.081 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA tRNA-synt_2c PF01411.19 KXZ50323.1 - 2.2e-209 696.6 0.0 2.7e-209 696.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 KXZ50323.1 - 1.6e-17 64.2 7.0 8.8e-17 61.8 7.0 2.3 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 KXZ50323.1 - 1.9e-17 63.1 0.0 3.8e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GST_C_2 PF13410.6 KXZ50323.1 - 0.042 13.9 1.0 0.22 11.6 1.0 2.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_24 PF13578.6 KXZ50325.1 - 2.4e-06 28.5 0.0 4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DEAD PF00270.29 KXZ50326.1 - 9.7e-12 45.0 0.0 5.3e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KXZ50326.1 - 1.3e-07 31.8 0.0 3.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXZ50326.1 - 0.16 12.2 0.0 5 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ribonuclease_3 PF00636.26 KXZ50327.1 - 3.1e-18 66.3 0.0 5.3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXZ50327.1 - 8.7e-07 29.1 0.0 3.8e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXZ50328.1 - 5.6e-14 52.7 0.8 1.7e-13 51.1 0.8 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXZ50328.1 - 1e-12 48.3 0.0 6.6e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXZ50329.1 - 2.6e-31 108.3 0.0 1.8e-18 67.1 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXZ50329.1 - 6.5e-23 81.3 0.2 9.1e-12 45.3 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KXZ50329.1 - 2.1e-16 59.9 0.0 7.4e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KXZ50330.1 - 1.2e-12 48.2 0.0 2.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ50330.1 - 1.1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ50330.1 - 4e-06 26.9 0.0 6.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Paramyxo_P_V_N PF13825.6 KXZ50331.1 - 0.21 11.0 0.5 0.28 10.6 0.5 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus ABC_tran PF00005.27 KXZ50332.1 - 2.6e-34 118.7 0.0 3.6e-27 95.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXZ50332.1 - 2.3e-29 102.9 9.5 8.7e-13 48.5 0.1 4.1 3 1 1 4 4 4 4 ABC transporter transmembrane region SMC_N PF02463.19 KXZ50332.1 - 5.3e-06 26.0 0.0 1 8.7 0.0 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KXZ50332.1 - 0.007 16.6 0.0 0.66 10.2 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KXZ50332.1 - 0.019 15.1 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KXZ50332.1 - 0.035 13.8 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KXZ50332.1 - 0.065 13.0 0.0 2.8 7.7 0.1 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXZ50332.1 - 0.22 11.6 0.0 0.35 10.9 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain PEPCK_ATP PF01293.20 KXZ50333.1 - 6e-163 542.8 0.0 1.8e-147 491.8 0.0 2.0 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KXZ50333.1 - 0.038 14.4 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXZ50333.1 - 0.04 14.1 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.26 KXZ50334.1 - 4.3e-24 84.8 0.0 4.7e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXZ50334.1 - 0.0059 16.3 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 KXZ50334.1 - 0.047 13.3 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 LON_substr_bdg PF02190.16 KXZ50336.1 - 7.7e-15 55.3 0.2 1.6e-14 54.3 0.2 1.4 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain PhdYeFM_antitox PF02604.19 KXZ50336.1 - 0.046 13.5 0.2 0.11 12.3 0.2 1.7 1 1 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Glyco_hydro_42 PF02449.15 KXZ50337.1 - 2.6e-06 27.0 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase AP_endonuc_2 PF01261.24 KXZ50337.1 - 0.0054 16.2 0.0 0.014 14.8 0.0 1.6 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Cellulase PF00150.18 KXZ50337.1 - 0.0079 15.7 0.0 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TT_ORF2 PF02957.15 KXZ50338.1 - 0.0013 19.7 5.1 0.022 15.7 0.2 2.4 2 0 0 2 2 2 1 TT viral ORF2 DASH_Spc19 PF08287.11 KXZ50338.1 - 0.011 15.6 1.8 0.02 14.8 1.8 1.3 1 0 0 1 1 1 0 Spc19 Tropomyosin_1 PF12718.7 KXZ50338.1 - 0.019 15.1 4.0 0.031 14.4 4.0 1.2 1 0 0 1 1 1 0 Tropomyosin like PSI_PsaF PF02507.15 KXZ50338.1 - 0.054 13.3 0.4 0.086 12.7 0.4 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Cnd1_N PF12922.7 KXZ50338.1 - 0.079 12.8 0.3 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Use1 PF09753.9 KXZ50338.1 - 0.09 12.5 1.9 0.18 11.5 1.9 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 Paralemmin PF03285.15 KXZ50338.1 - 1.3 8.5 6.9 0.07 12.7 1.6 1.4 2 0 0 2 2 2 0 Paralemmin TraT PF05818.12 KXZ50338.1 - 3.9 7.1 9.4 0.17 11.6 3.7 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein NTase_sub_bind PF08780.11 KXZ50341.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.4 1 1 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like UTP15_C PF09384.10 KXZ50342.1 - 0.021 14.5 0.2 0.031 14.0 0.2 1.2 1 0 0 1 1 1 0 UTP15 C terminal Flavodoxin_3 PF12641.7 KXZ50343.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain tRNA-synt_His PF13393.6 KXZ50344.1 - 0.03 13.6 0.1 0.032 13.5 0.1 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase D5_N PF08706.11 KXZ50345.1 - 1.7e-13 51.1 0.0 4.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 D5 N terminal like PriCT_2 PF08707.11 KXZ50345.1 - 1.2e-10 41.6 0.8 9.9e-10 38.7 0.1 2.4 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) Prim-Pol PF09250.11 KXZ50345.1 - 1.5e-07 32.0 0.0 4.2e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Bifunctional DNA primase/polymerase, N-terminal T5orf172 PF10544.9 KXZ50345.1 - 9.8e-06 26.1 0.2 2.7e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KXZ50345.1 - 0.0064 17.2 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Adenylsucc_synt PF00709.21 KXZ50346.1 - 0.00059 18.9 0.2 0.00067 18.7 0.2 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Gp37 PF09646.10 KXZ50346.1 - 0.044 13.6 0.1 0.054 13.3 0.1 1.3 1 0 0 1 1 1 0 Gp37 protein DUF496 PF04363.12 KXZ50347.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF496) DASH_Dad4 PF08650.10 KXZ50348.1 - 0.0012 18.8 0.3 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 DASH complex subunit Dad4 Phage_fiber_2 PF03406.13 KXZ50348.1 - 0.23 11.0 2.8 0.56 9.8 1.6 2.1 2 0 0 2 2 2 0 Phage tail fibre repeat Phage_GP20 PF06810.11 KXZ50349.1 - 2.7e-05 24.0 2.5 0.03 14.1 0.4 2.1 1 1 1 2 2 2 2 Phage minor structural protein GP20 DivIC PF04977.15 KXZ50349.1 - 5.4e-05 22.9 5.9 0.1 12.3 0.9 3.1 1 1 2 3 3 3 2 Septum formation initiator ZapB PF06005.12 KXZ50349.1 - 0.00017 22.0 1.1 0.013 16.0 0.6 2.3 1 1 1 2 2 2 1 Cell division protein ZapB CENP-F_leu_zip PF10473.9 KXZ50349.1 - 0.00035 20.6 0.6 0.0012 18.9 0.6 1.7 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 KXZ50349.1 - 0.00044 20.6 1.6 3.3 8.2 0.1 3.3 1 1 1 3 3 3 1 Flagella accessory protein C (FlaC) HALZ PF02183.18 KXZ50349.1 - 0.00083 19.5 1.4 0.071 13.3 0.0 3.1 1 1 1 3 3 3 1 Homeobox associated leucine zipper GAS PF13851.6 KXZ50349.1 - 0.0026 17.2 0.0 0.0042 16.5 0.0 1.3 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 KXZ50349.1 - 0.0033 17.4 0.8 0.66 10.0 0.1 2.5 1 1 2 3 3 3 1 Prefoldin subunit DUF948 PF06103.11 KXZ50349.1 - 0.0033 17.6 2.5 0.048 13.9 0.2 2.3 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) KASH_CCD PF14662.6 KXZ50349.1 - 0.0036 17.1 1.3 0.0042 16.9 1.3 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 KXZ50349.1 - 0.0042 17.3 4.1 0.13 12.4 3.5 2.1 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 KXZ50349.1 - 0.0045 17.3 2.6 0.14 12.5 0.3 2.3 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.12 KXZ50349.1 - 0.0048 16.5 0.7 0.0095 15.5 0.7 1.5 1 1 0 1 1 1 1 PspA/IM30 family APG6_N PF17675.1 KXZ50349.1 - 0.0052 17.3 0.1 0.007 16.9 0.1 1.3 1 1 0 1 1 1 1 Apg6 coiled-coil region MCC-bdg_PDZ PF10506.9 KXZ50349.1 - 0.0058 16.6 0.5 0.075 13.0 0.1 2.4 2 1 1 3 3 3 1 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1664 PF07889.12 KXZ50349.1 - 0.0081 16.2 1.6 0.034 14.2 1.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 KXZ50349.1 - 0.0087 16.1 1.8 0.2 11.7 0.1 2.8 1 1 1 3 3 3 1 bZIP transcription factor Spc7 PF08317.11 KXZ50349.1 - 0.019 13.8 1.7 0.12 11.3 0.2 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Prefoldin PF02996.17 KXZ50349.1 - 0.02 14.8 1.0 0.39 10.6 0.1 2.5 1 1 1 3 3 3 0 Prefoldin subunit DUF16 PF01519.16 KXZ50349.1 - 0.021 15.3 3.5 0.98 9.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 ADIP PF11559.8 KXZ50349.1 - 0.026 14.6 0.3 0.075 13.1 0.1 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 KXZ50349.1 - 0.026 15.0 3.9 0.93 10.0 4.0 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 KXZ50349.1 - 0.028 13.7 0.8 0.27 10.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlxA PF14282.6 KXZ50349.1 - 0.041 13.9 3.1 0.099 12.6 3.0 1.8 1 1 0 1 1 1 0 FlxA-like protein TACC_C PF05010.14 KXZ50349.1 - 0.043 13.6 0.1 0.097 12.4 0.1 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlgN PF05130.12 KXZ50349.1 - 0.046 14.2 3.8 0.061 13.8 3.8 1.1 1 0 0 1 1 1 0 FlgN protein YabA PF06156.13 KXZ50349.1 - 0.046 14.4 0.3 0.5 11.0 0.3 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Sipho_Gp157 PF05565.11 KXZ50349.1 - 0.058 13.4 1.5 0.088 12.8 0.6 1.6 1 1 1 2 2 2 0 Siphovirus Gp157 Laminin_II PF06009.12 KXZ50349.1 - 0.072 13.1 3.1 1.1 9.3 0.3 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF4200 PF13863.6 KXZ50349.1 - 0.072 13.5 0.5 1.2 9.5 0.3 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KXZ50349.1 - 0.075 13.1 0.4 0.16 12.1 0.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TSC22 PF01166.18 KXZ50349.1 - 0.086 13.2 0.4 12 6.3 0.0 3.0 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF4795 PF16043.5 KXZ50349.1 - 0.099 12.2 1.0 0.99 9.0 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TBCC_N PF16752.5 KXZ50349.1 - 0.1 13.1 0.2 11 6.5 0.0 2.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain ABC_tran_CTD PF16326.5 KXZ50349.1 - 0.12 12.7 1.5 2.4 8.5 0.2 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain SKA1 PF07160.12 KXZ50349.1 - 0.13 12.1 1.3 0.67 9.8 0.3 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 LPP PF04728.13 KXZ50349.1 - 0.2 12.1 3.0 2.9 8.3 0.0 2.8 2 1 1 3 3 2 0 Lipoprotein leucine-zipper SlyX PF04102.12 KXZ50349.1 - 0.25 12.0 1.5 3.3 8.4 0.9 2.5 1 1 1 2 2 2 0 SlyX Mto2_bdg PF12808.7 KXZ50349.1 - 1.1 9.6 3.9 1.9 8.9 0.3 2.6 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4407 PF14362.6 KXZ50350.1 - 0.12 11.7 3.3 0.15 11.4 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tugs PF17840.1 KXZ50350.1 - 0.13 12.5 2.8 0.13 12.4 0.5 2.2 1 1 1 2 2 2 0 Tethering Ubl4a to BAGS domain MH1 PF03165.16 KXZ50350.1 - 0.14 12.4 1.1 0.54 10.5 1.1 1.9 1 1 0 1 1 1 0 MH1 domain HNH_3 PF13392.6 KXZ50352.1 - 4.1e-05 23.3 0.0 6.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease DUF386 PF04074.12 KXZ50354.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 YhcH/YjgK/YiaL Peptidase_C48 PF02902.19 KXZ50355.1 - 0.0001 22.2 0.2 0.012 15.5 0.0 2.3 1 1 1 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain JmjC PF02373.22 KXZ50356.1 - 0.0035 17.8 0.2 0.0062 16.9 0.2 1.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase DOT1 PF08123.13 KXZ50357.1 - 0.059 12.9 0.3 0.084 12.4 0.3 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Rad60-SLD PF11976.8 KXZ50359.1 - 6.3e-15 54.8 0.0 8.6e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXZ50359.1 - 6.2e-05 22.7 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Flu_B_NS1 PF02942.14 KXZ50359.1 - 0.035 13.2 0.1 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) YpjP PF14005.6 KXZ50359.1 - 0.049 13.7 0.4 0.07 13.2 0.4 1.2 1 0 0 1 1 1 0 YpjP-like protein Peptidase_S26 PF10502.9 KXZ50361.1 - 0.029 14.2 0.1 0.77 9.5 0.0 2.2 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KXZ50361.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Peptidase S24-like Tudor-knot PF11717.8 KXZ50362.1 - 2.5e-10 40.1 1.1 3.6e-10 39.6 1.1 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF3446 PF11928.8 KXZ50363.1 - 0.11 12.8 6.1 0.26 11.6 6.1 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain Mito_carr PF00153.27 KXZ50364.1 - 1.8e-22 79.0 2.3 1e-13 51.0 0.2 2.6 2 1 1 3 3 3 2 Mitochondrial carrier protein RecC_C PF17946.1 KXZ50365.1 - 0.016 15.0 3.6 0.087 12.6 0.3 2.9 3 0 0 3 3 3 0 RecC C-terminal domain Thioredoxin PF00085.20 KXZ50366.1 - 3.1e-29 101.0 0.1 3.7e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXZ50366.1 - 5.5e-05 23.4 0.0 0.00045 20.5 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXZ50366.1 - 0.00026 21.4 0.1 0.00039 20.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KXZ50366.1 - 0.0034 17.3 0.0 0.0041 17.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KXZ50366.1 - 0.033 14.4 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 KXZ50366.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 KXZ50366.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin GBP PF02263.19 KXZ50367.1 - 5.2e-66 222.6 0.0 8.5e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KXZ50367.1 - 1.3e-16 60.9 24.7 1.3e-16 60.9 24.7 2.8 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain ABC_tran PF00005.27 KXZ50367.1 - 1.7e-13 51.3 5.0 2.3e-13 50.8 0.0 3.2 3 1 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 KXZ50367.1 - 0.022 15.3 0.1 0.1 13.1 0.1 2.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXZ50367.1 - 0.076 13.1 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase EzrA PF06160.12 KXZ50367.1 - 0.22 9.7 15.0 1.5 6.9 9.2 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA AAA_22 PF13401.6 KXZ50367.1 - 1.8 8.9 11.9 0.4 11.0 0.1 3.7 3 1 0 3 3 3 0 AAA domain ABC_membrane PF00664.23 KXZ50368.1 - 1.9e-28 99.9 1.6 2e-28 99.8 1.6 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_U4 PF03419.13 KXZ50368.1 - 8.9 5.5 8.5 61 2.8 8.5 1.9 1 1 0 1 1 1 0 Sporulation factor SpoIIGA RLL PF10036.9 KXZ50369.1 - 0.0078 16.1 5.4 0.0078 16.1 5.4 3.5 4 0 0 4 4 4 1 RNA transcription, translation and transport factor protein ATG22 PF11700.8 KXZ50369.1 - 0.45 9.1 2.6 1.6 7.3 0.4 2.2 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Glt_symporter PF03616.14 KXZ50369.1 - 4.5 5.8 4.4 26 3.3 0.5 2.5 2 0 0 2 2 2 0 Sodium/glutamate symporter Porin_3 PF01459.22 KXZ50370.1 - 6.9e-06 25.7 2.7 0.037 13.5 0.0 3.8 3 1 0 4 4 4 3 Eukaryotic porin Glyco_transf_90 PF05686.12 KXZ50371.1 - 0.0012 17.8 0.1 0.0013 17.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Cupin_8 PF13621.6 KXZ50372.1 - 7.9e-14 52.0 0.0 8.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXZ50372.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein SpoVS PF04232.12 KXZ50373.1 - 1.3e-38 130.6 2.3 7.5e-25 86.5 0.5 2.1 2 0 0 2 2 2 2 Stage V sporulation protein S (SpoVS) zf-MYND PF01753.18 KXZ50374.1 - 1.9e-10 40.6 19.9 5.4e-10 39.2 19.9 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ50374.1 - 6.5 7.1 14.3 15 6.0 14.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TFIIA PF03153.13 KXZ50375.1 - 0.12 12.4 21.5 0.14 12.1 21.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hint PF01079.20 KXZ50376.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Hint module EF-hand_1 PF00036.32 KXZ50376.1 - 1.2e-05 24.5 0.5 2.2e-05 23.7 0.5 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ50376.1 - 0.00045 19.6 0.1 0.00091 18.6 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ50376.1 - 0.004 17.0 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain CopD PF05425.13 KXZ50376.1 - 0.0095 16.3 0.1 0.031 14.7 0.1 1.9 1 0 0 1 1 1 1 Copper resistance protein D EF-hand_7 PF13499.6 KXZ50376.1 - 0.066 13.7 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair G0-G1_switch_2 PF15103.6 KXZ50376.1 - 0.093 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 EF-hand_8 PF13833.6 KXZ50376.1 - 0.11 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair zf-C2H2_10 PF16588.5 KXZ50377.1 - 0.0019 17.9 4.0 0.0046 16.7 4.0 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger Hint PF01079.20 KXZ50378.1 - 1.4e-17 63.9 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Hint module EF-hand_1 PF00036.32 KXZ50379.1 - 5.9e-05 22.3 0.3 0.0001 21.6 0.3 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ50379.1 - 0.00098 18.5 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ50379.1 - 0.0097 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain CopD PF05425.13 KXZ50379.1 - 0.01 16.2 0.9 0.022 15.1 0.0 2.0 2 0 0 2 2 2 0 Copper resistance protein D LapA_dom PF06305.11 KXZ50379.1 - 0.086 12.7 0.9 0.2 11.5 0.9 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain G0-G1_switch_2 PF15103.6 KXZ50379.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 PDDEXK_6 PF04720.12 KXZ50380.1 - 1.8e-16 60.8 0.0 2.9e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 PDDEXK-like family of unknown function Leo1 PF04004.13 KXZ50381.1 - 7.9e-35 120.1 0.0 1.9e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Leo1-like protein DUF2540 PF10802.8 KXZ50381.1 - 0.18 11.9 0.0 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) EF-1_beta_acid PF10587.9 KXZ50381.1 - 0.18 12.3 0.3 0.18 12.3 0.3 9.7 11 0 0 11 11 11 0 Eukaryotic elongation factor 1 beta central acidic region PHD PF00628.29 KXZ50382.1 - 1.7e-06 27.8 8.4 2.8e-06 27.1 8.4 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 KXZ50382.1 - 0.059 13.0 2.0 0.13 11.9 2.0 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KXZ50382.1 - 0.45 10.4 6.7 0.086 12.7 3.1 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KXZ50382.1 - 2.3 8.4 7.3 5.7 7.1 7.3 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KXZ50382.1 - 4.3 7.4 7.1 1.1 9.3 3.7 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DinB_2 PF12867.7 KXZ50383.1 - 0.065 13.7 0.9 0.19 12.2 0.9 1.9 1 0 0 1 1 1 0 DinB superfamily DHHC PF01529.20 KXZ50386.1 - 1e-22 80.7 2.4 2.1e-22 79.7 2.4 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3040 PF11239.8 KXZ50386.1 - 3.2 8.1 7.3 0.88 9.9 1.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) WD40 PF00400.32 KXZ50387.1 - 4.2e-13 49.6 13.8 4.8e-07 30.4 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_N PF14781.6 KXZ50387.1 - 0.21 11.5 0.0 0.5 10.3 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal UQ_con PF00179.26 KXZ50388.1 - 1.6e-54 183.4 0.0 1.8e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXZ50388.1 - 0.00013 21.6 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXZ50388.1 - 0.0014 18.9 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXZ50388.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Fib_alpha PF08702.10 KXZ50389.1 - 0.3 11.3 2.5 0.95 9.6 0.1 3.0 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family PDDEXK_6 PF04720.12 KXZ50390.1 - 8e-22 78.3 0.0 1.2e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 PDDEXK-like family of unknown function PDDEXK_6 PF04720.12 KXZ50391.1 - 5.7e-21 75.5 0.0 8.1e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 PDDEXK-like family of unknown function zf-MYND PF01753.18 KXZ50392.1 - 2 8.6 7.9 0.78 9.9 1.2 2.4 2 0 0 2 2 2 0 MYND finger WSC PF01822.19 KXZ50393.1 - 0.0012 19.0 1.0 0.0019 18.4 1.0 1.2 1 0 0 1 1 1 1 WSC domain EGF_2 PF07974.13 KXZ50394.1 - 0.0084 16.5 3.3 0.0084 16.5 3.3 2.5 2 1 0 2 2 2 1 EGF-like domain ABC2_membrane PF01061.24 KXZ50395.1 - 2.6e-36 125.0 7.3 2.6e-36 125.0 7.3 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ50395.1 - 8.3e-05 23.1 0.0 0.00015 22.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF5325 PF17259.2 KXZ50395.1 - 0.027 14.3 1.5 0.069 13.0 1.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5325) PDR_CDR PF06422.12 KXZ50395.1 - 0.032 14.1 0.0 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 CDR ABC transporter AAA_21 PF13304.6 KXZ50395.1 - 0.27 11.0 0.0 0.37 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PAS PF00989.25 KXZ50396.1 - 1.1e-06 28.5 0.0 0.018 15.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KXZ50396.1 - 3.6e-05 23.7 0.0 0.028 14.5 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 KXZ50396.1 - 0.0015 18.8 0.0 0.016 15.4 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KXZ50396.1 - 0.0057 16.9 0.1 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 KXZ50396.1 - 0.1 12.7 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold Ldr_toxin PF13940.6 KXZ50400.1 - 0.099 12.7 2.8 0.091 12.8 0.8 2.1 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system DUF2946 PF11162.8 KXZ50400.1 - 7.2 7.3 27.9 0.38 11.4 9.2 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2946) Pkinase_Tyr PF07714.17 KXZ50401.1 - 1.3e-27 96.8 0.0 5.6e-14 52.0 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50401.1 - 2.2e-23 83.0 0.0 2.8e-10 40.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Alg6_Alg8 PF03155.15 KXZ50402.1 - 9.8e-55 186.4 2.5 1.1e-47 163.1 2.8 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DNApol_Exo PF18136.1 KXZ50405.1 - 0.079 12.1 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain Lipase_GDSL_2 PF13472.6 KXZ50405.1 - 0.13 12.6 0.9 0.52 10.7 0.1 2.0 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Peptidase_C48 PF02902.19 KXZ50406.1 - 1.1e-23 84.2 0.0 1.6e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KXZ50406.1 - 0.004 15.9 0.0 0.01 14.6 0.0 1.7 1 1 0 1 1 1 1 Vaccinia virus I7 processing peptidase Acyl-CoA_dh_1 PF00441.24 KXZ50409.1 - 2e-11 44.3 0.0 9.6e-11 42.1 0.0 1.8 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KXZ50409.1 - 0.0092 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXZ50409.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain 3HCDH_N PF02737.18 KXZ50410.1 - 3.5e-39 134.5 0.0 2e-38 132.1 0.0 2.0 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXZ50410.1 - 8.1e-29 100.1 0.3 1.6e-22 79.9 0.1 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 KXZ50410.1 - 1.3e-20 73.8 0.0 2.4e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXZ50410.1 - 3e-13 50.0 0.0 3e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Pyr_redox_2 PF07992.14 KXZ50410.1 - 0.057 12.7 0.2 0.093 11.9 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KXZ50410.1 - 0.15 12.7 0.7 0.43 11.2 0.7 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sulfotransfer_3 PF13469.6 KXZ50411.1 - 0.0099 16.3 0.1 0.034 14.5 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase family RVT_1 PF00078.27 KXZ50413.1 - 5.8e-06 26.0 0.0 8.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 KXZ50413.1 - 0.033 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) ABATE PF07336.11 KXZ50414.1 - 0.15 12.7 2.6 0.34 11.6 2.6 1.6 1 1 0 1 1 1 0 Putative stress-induced transcription regulator efThoc1 PF11957.8 KXZ50415.1 - 8.8e-41 140.1 0.0 2.5e-34 118.8 0.0 2.5 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor ABC_tran PF00005.27 KXZ50416.1 - 1.8e-24 86.8 0.0 2.7e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KXZ50416.1 - 0.00011 22.7 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KXZ50416.1 - 0.0012 18.7 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ50416.1 - 0.0014 18.1 0.1 1.1 8.7 0.1 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXZ50416.1 - 0.0016 18.4 0.4 0.0028 17.6 0.4 1.3 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KXZ50416.1 - 0.0037 17.2 0.1 0.0069 16.3 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 KXZ50416.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KXZ50416.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXZ50416.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KXZ50416.1 - 0.22 11.8 0.1 0.72 10.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 KXZ50417.1 - 1.2e-10 41.8 0.0 3.8e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ50417.1 - 1.1e-09 38.2 0.0 2.7e-05 24.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXZ50417.1 - 6e-08 32.4 0.0 0.015 15.8 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXZ50417.1 - 9.2e-08 32.2 0.0 0.033 14.5 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ50417.1 - 1.8e-07 31.5 0.0 0.0074 16.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ50418.1 - 6.5e-23 81.1 0.1 2.5e-09 37.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ50418.1 - 9.9e-17 60.8 0.1 1.8e-08 34.5 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ50418.1 - 5.3e-15 55.6 0.0 6.6e-08 32.9 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ50418.1 - 7.7e-15 54.6 3.9 2e-05 24.8 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KXZ50418.1 - 1.3e-14 52.8 0.8 0.0031 17.9 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat cobW PF02492.19 KXZ50419.1 - 1e-56 191.3 0.2 1.5e-56 190.7 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ50419.1 - 1.9e-15 56.6 0.0 3.6e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain T2SSE PF00437.20 KXZ50419.1 - 0.001 18.2 0.1 0.0018 17.4 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KXZ50419.1 - 0.0026 17.7 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 KXZ50419.1 - 0.0049 16.8 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Arf PF00025.21 KXZ50419.1 - 0.0085 15.6 0.4 0.55 9.7 0.2 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.6 KXZ50419.1 - 0.01 16.4 0.3 0.037 14.6 0.2 2.1 2 1 0 2 2 2 1 AAA domain MobB PF03205.14 KXZ50419.1 - 0.041 13.8 0.0 0.041 13.8 0.0 2.5 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 KXZ50419.1 - 0.058 12.4 0.7 0.34 9.9 0.1 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 KXZ50419.1 - 0.085 12.9 0.1 0.4 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXZ50419.1 - 0.088 12.9 0.6 0.78 9.8 0.6 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 KXZ50419.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KXZ50419.1 - 0.14 12.6 0.2 0.34 11.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KXZ50419.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ50419.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain SBP PF03110.14 KXZ50420.1 - 8.9e-24 83.6 7.4 1.4e-23 82.9 7.4 1.3 1 0 0 1 1 1 1 SBP domain Cse1 PF08506.10 KXZ50420.1 - 0.26 10.1 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Cse1 FGGY_C PF02782.16 KXZ50423.1 - 9.8e-62 208.2 1.7 9.8e-62 208.2 1.7 2.4 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXZ50423.1 - 4.8e-54 183.5 0.2 1.2e-50 172.4 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Zip PF02535.22 KXZ50424.1 - 4.4e-50 170.8 7.3 4.4e-50 170.8 7.3 2.0 2 1 0 2 2 2 1 ZIP Zinc transporter DUF4690 PF15756.5 KXZ50425.1 - 0.071 13.7 2.4 0.29 11.8 2.4 2.1 1 0 0 1 1 1 0 Small Novel Rich in Cartilage IU_nuc_hydro PF01156.19 KXZ50426.1 - 7.5e-61 206.3 0.4 1.9e-53 182.0 0.0 2.7 1 1 1 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.25 KXZ50427.1 - 1.6e-49 168.7 0.0 2.1e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50427.1 - 1.1e-26 93.7 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50427.1 - 9.5e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ50427.1 - 3.6e-07 29.3 0.0 5.7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ50427.1 - 0.016 15.2 0.2 0.016 15.2 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ50427.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBX PF00789.20 KXZ50428.1 - 2.8e-06 27.4 0.0 7.1e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 UBX domain Selenoprotein_S PF06936.11 KXZ50428.1 - 0.056 13.3 3.6 0.077 12.8 3.6 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Nucleoside_tran PF01733.18 KXZ50428.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter DUF4813 PF16072.5 KXZ50428.1 - 3.8 7.1 6.0 5.4 6.6 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) ISN1 PF06437.11 KXZ50429.1 - 5.7e-96 321.9 0.0 7.1e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Hydrolase_3 PF08282.12 KXZ50429.1 - 0.00077 19.3 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ50429.1 - 0.0032 17.8 0.1 0.069 13.4 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PTR2 PF00854.21 KXZ50431.1 - 5.6e-109 364.6 4.1 1.1e-55 189.1 0.0 2.3 2 0 0 2 2 2 2 POT family MFS_1 PF07690.16 KXZ50431.1 - 2.3e-08 33.4 5.6 2.3e-08 33.4 5.6 3.2 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF4191 PF13829.6 KXZ50431.1 - 0.063 12.6 0.0 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Synaptobrevin PF00957.21 KXZ50432.1 - 1.7e-33 114.3 2.4 2.7e-33 113.6 2.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXZ50432.1 - 7.7e-15 54.7 0.0 1.5e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain N6_N4_Mtase PF01555.18 KXZ50432.1 - 0.012 15.3 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 DNA methylase DUF1048 PF06304.11 KXZ50432.1 - 0.028 14.9 0.8 9.1 6.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1048) DUF2937 PF11157.8 KXZ50432.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Fzo_mitofusin PF04799.13 KXZ50432.1 - 0.12 11.9 0.8 0.21 11.2 0.8 1.4 1 0 0 1 1 1 0 fzo-like conserved region CENP-T_C PF15511.6 KXZ50433.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50433.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ50433.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ50433.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50433.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ50433.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ50433.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated CHASE3 PF05227.13 KXZ50434.1 - 0.086 12.7 0.5 10 6.0 0.0 2.4 2 0 0 2 2 2 0 CHASE3 domain MYCBPAP PF14646.6 KXZ50435.1 - 2.4e-13 49.9 0.0 3.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 MYCBP-associated protein family Nas2_N PF18265.1 KXZ50436.1 - 2.3e-26 91.5 0.0 3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KXZ50436.1 - 5.5e-06 26.1 0.8 3.2e-05 23.7 0.2 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KXZ50436.1 - 0.00096 19.4 0.0 0.0057 16.9 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KXZ50436.1 - 0.062 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 PDZ domain POR_N PF01855.19 KXZ50436.1 - 0.18 11.5 3.7 0.26 11.0 3.7 1.2 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CBM_20 PF00686.19 KXZ50437.1 - 0.00018 21.4 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Starch binding domain Asp PF00026.23 KXZ50438.1 - 6.9e-112 373.9 0.0 7.7e-111 370.5 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXZ50438.1 - 1.9e-10 41.3 0.4 2.1e-08 34.6 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal SapB_1 PF05184.15 KXZ50438.1 - 2.8e-07 30.4 0.3 6.5e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 1 SapB_2 PF03489.17 KXZ50438.1 - 1.2e-05 25.3 0.9 1.7e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 TAXi_C PF14541.6 KXZ50438.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Plant_NMP1 PF06694.11 KXZ50438.1 - 0.44 9.6 1.4 0.62 9.1 1.4 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) MutL_C PF08676.11 KXZ50440.1 - 0.0041 16.9 0.0 0.09 12.5 0.0 2.4 3 0 0 3 3 3 1 MutL C terminal dimerisation domain TIC20 PF16166.5 KXZ50442.1 - 1.4e-32 112.9 2.9 1.7e-32 112.7 2.9 1.0 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like CENP-T_C PF15511.6 KXZ50443.1 - 3.3e-09 36.8 0.0 4.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50443.1 - 0.00014 22.2 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ50443.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ50443.1 - 0.0014 18.9 0.1 0.0023 18.2 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50443.1 - 0.0019 18.6 0.2 0.0024 18.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ50443.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ50443.1 - 0.021 14.8 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ50444.1 - 1.2e-36 126.0 3.4 4.3e-36 124.2 3.4 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXZ50444.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50444.1 - 0.00081 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXZ50444.1 - 0.0034 17.6 0.1 0.0052 17.0 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ50444.1 - 0.043 13.9 0.0 0.058 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit ABC2_membrane PF01061.24 KXZ50445.1 - 6.9e-75 251.1 54.3 3.3e-38 131.2 20.7 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXZ50445.1 - 5e-35 121.0 0.0 3.2e-16 60.1 0.0 2.7 2 1 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 KXZ50445.1 - 2.6e-10 39.9 9.2 1.1e-09 37.9 0.0 3.7 3 0 0 3 3 3 1 Plant PDR ABC transporter associated AAA_29 PF13555.6 KXZ50445.1 - 1e-06 28.4 0.5 0.05 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ50445.1 - 1.4e-05 25.6 0.2 0.18 12.1 0.0 3.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KXZ50445.1 - 0.00029 20.6 0.1 0.056 13.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KXZ50445.1 - 0.00081 19.5 0.3 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KXZ50445.1 - 0.0011 18.5 0.2 0.52 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KXZ50445.1 - 0.0013 17.9 16.5 0.0013 17.9 16.5 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 KXZ50445.1 - 0.0018 18.8 0.6 1.8 9.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KXZ50445.1 - 0.0021 18.5 0.4 1.2 9.6 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PDR_CDR PF06422.12 KXZ50445.1 - 0.0023 17.8 2.2 0.29 11.0 0.5 2.9 2 0 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 KXZ50445.1 - 0.0035 17.3 1.5 0.39 10.6 0.6 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KXZ50445.1 - 0.015 15.0 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KXZ50445.1 - 0.016 15.1 0.0 13 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_19 PF13245.6 KXZ50445.1 - 0.019 15.3 0.1 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXZ50445.1 - 0.044 13.9 0.8 13 6.0 0.1 3.3 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXZ50445.1 - 0.052 13.5 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KXZ50445.1 - 0.052 13.9 0.1 5.2 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KXZ50445.1 - 0.064 13.5 7.1 1.5 9.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_trans_N PF14510.6 KXZ50445.1 - 0.081 13.5 0.1 0.23 12.1 0.0 1.8 2 0 0 2 2 1 0 ABC-transporter N-terminal SMC_N PF02463.19 KXZ50445.1 - 0.09 12.2 0.0 2 7.8 0.0 2.8 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain FeoB_N PF02421.18 KXZ50445.1 - 0.11 12.0 0.8 7.4 6.1 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_22 PF13401.6 KXZ50445.1 - 0.14 12.4 0.7 26 5.1 0.4 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KXZ50445.1 - 0.72 9.7 1.9 19 5.1 0.6 2.5 2 0 0 2 2 2 0 NACHT domain Glyco_transf_90 PF05686.12 KXZ50446.1 - 1.1e-27 97.0 0.2 1.4e-27 96.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXZ50446.1 - 0.00017 21.9 0.3 0.00047 20.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 PNISR PF15996.5 KXZ50447.1 - 9.4e-11 42.4 11.5 2.7e-10 40.9 1.3 2.7 2 1 1 3 3 3 2 Arginine/serine-rich protein PNISR ABC2_membrane PF01061.24 KXZ50448.1 - 7.1e-72 241.2 54.9 1.3e-37 129.3 25.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXZ50448.1 - 3e-35 121.7 0.0 5.1e-16 59.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 KXZ50448.1 - 1.1e-09 37.9 0.0 1.1e-09 37.9 0.0 3.5 3 0 0 3 3 3 1 Plant PDR ABC transporter associated AAA_21 PF13304.6 KXZ50448.1 - 1.1e-07 32.0 0.1 0.012 15.5 0.0 4.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ50448.1 - 1.1e-06 28.3 0.5 0.05 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ50448.1 - 2.1e-05 25.0 1.8 0.32 11.4 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain AAA_30 PF13604.6 KXZ50448.1 - 0.00042 20.1 0.5 0.048 13.4 0.1 2.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KXZ50448.1 - 0.00058 19.9 0.4 0.25 11.5 0.0 2.7 3 0 0 3 3 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 KXZ50448.1 - 0.00076 19.0 0.3 5.3 6.4 0.0 3.9 5 0 0 5 5 5 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXZ50448.1 - 0.0011 19.5 0.7 1.2 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXZ50448.1 - 0.0011 18.6 0.3 0.64 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KXZ50448.1 - 0.0021 18.5 0.1 1.3 9.5 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KXZ50448.1 - 0.0028 17.6 1.0 0.35 10.8 0.3 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KXZ50448.1 - 0.011 16.0 4.9 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KXZ50448.1 - 0.011 15.5 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 KXZ50448.1 - 0.017 14.3 49.8 0.31 10.1 17.8 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein Rad17 PF03215.15 KXZ50448.1 - 0.043 13.8 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 KXZ50448.1 - 0.045 13.9 1.1 16 5.6 0.0 3.4 2 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXZ50448.1 - 0.049 14.0 0.0 4.8 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KXZ50448.1 - 0.054 13.8 0.0 7.6 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KXZ50448.1 - 0.11 12.0 0.5 7.5 6.1 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_22 PF13401.6 KXZ50448.1 - 0.28 11.5 1.7 26 5.1 0.4 2.9 3 0 0 3 3 2 0 AAA domain ANAPC_CDC26 PF10471.9 KXZ50448.1 - 0.29 12.0 1.4 16 6.4 0.2 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 AAA_18 PF13238.6 KXZ50448.1 - 4.5 7.8 4.9 28 5.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain NAD_binding_2 PF03446.15 KXZ50449.1 - 2e-37 128.8 1.1 2e-37 128.8 1.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXZ50449.1 - 2.5e-27 95.6 2.4 4.5e-27 94.7 2.4 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXZ50449.1 - 1.6e-05 25.4 0.3 3.7e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXZ50449.1 - 0.00011 22.3 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXZ50449.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KXZ50449.1 - 0.11 12.1 0.1 0.35 10.5 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Synaptobrevin PF00957.21 KXZ50450.1 - 2.9e-24 84.6 1.5 4.5e-24 84.1 1.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXZ50450.1 - 1.4e-11 44.3 0.0 2.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain YlqD PF11068.8 KXZ50450.1 - 0.0034 17.8 0.1 0.0045 17.4 0.1 1.1 1 0 0 1 1 1 1 YlqD protein Synaptobrevin PF00957.21 KXZ50451.1 - 2.3e-31 107.4 2.3 3.5e-31 106.9 2.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXZ50451.1 - 1.3e-21 76.5 0.1 2e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF844 PF05815.11 KXZ50451.1 - 0.028 13.6 0.7 0.1 11.8 0.3 1.8 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF844) PLU-1 PF08429.11 KXZ50451.1 - 0.029 13.6 1.2 0.046 12.9 1.2 1.2 1 0 0 1 1 1 0 PLU-1-like protein DUF3671 PF12420.8 KXZ50451.1 - 0.037 14.1 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function Spc7 PF08317.11 KXZ50451.1 - 0.038 12.9 2.6 0.051 12.5 2.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein LMBR1 PF04791.16 KXZ50451.1 - 0.063 12.2 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NACHT PF05729.12 KXZ50451.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Utp12 PF04003.12 KXZ50451.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family SLC3A2_N PF16028.5 KXZ50451.1 - 0.26 10.9 1.4 0.44 10.1 1.4 1.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Bromodomain PF00439.25 KXZ50452.1 - 1.9e-21 75.9 0.0 3.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Sulfatase PF00884.23 KXZ50453.1 - 7.2e-50 170.1 0.1 9.8e-50 169.7 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXZ50453.1 - 2.4e-06 27.4 0.1 1.5e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase CAP_N PF01213.19 KXZ50453.1 - 0.43 10.0 15.9 0.07 12.6 1.8 3.0 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 KXZ50454.1 - 2.3e-62 210.8 0.0 3.7e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50454.1 - 1e-32 113.5 0.0 1.4e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50454.1 - 3.4e-05 23.3 0.3 0.00019 20.9 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXZ50454.1 - 0.00014 20.9 1.3 0.00044 19.3 1.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXZ50454.1 - 0.0027 16.5 0.0 0.011 14.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase FeoB_N PF02421.18 KXZ50454.1 - 0.013 15.0 0.2 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Kdo PF06293.14 KXZ50454.1 - 0.019 14.3 0.5 0.037 13.4 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ50454.1 - 0.05 13.5 0.9 5.1 6.9 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family TAF4 PF05236.14 KXZ50454.1 - 1.9 8.1 7.4 3.4 7.3 7.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family LCM PF04072.14 KXZ50455.1 - 4.2e-23 82.3 0.1 1.6e-22 80.4 0.1 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Sulfatase PF00884.23 KXZ50457.1 - 1.1e-49 169.5 0.0 1.4e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KXZ50457.1 - 0.084 11.5 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) K_channel_TID PF07941.11 KXZ50458.1 - 0.035 14.6 0.7 0.035 14.6 0.7 8.0 5 3 3 8 8 8 0 Potassium channel Kv1.4 tandem inactivation domain RVT_2 PF07727.14 KXZ50459.1 - 5.3e-69 232.5 0.0 1e-68 231.6 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KXZ50459.1 - 2.3e-22 79.4 0.0 6.1e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KXZ50459.1 - 7.6e-07 28.8 0.0 3e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF4410 PF14366.6 KXZ50459.1 - 0.15 11.9 2.7 0.29 11.1 0.1 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4410) Histone PF00125.24 KXZ50460.1 - 3.2e-22 79.3 6.8 4.3e-22 78.9 6.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50460.1 - 8.2e-05 22.8 0.1 8.2e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ50460.1 - 0.0019 18.7 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ50460.1 - 0.0091 15.7 0.5 0.4 10.3 0.1 2.1 1 1 1 2 2 2 1 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ50460.1 - 0.019 15.0 5.5 0.037 14.1 5.5 1.5 1 1 0 1 1 1 0 YscO-like protein DUF1839 PF08893.10 KXZ50460.1 - 0.13 11.5 0.3 0.15 11.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Spore_coat_CotO PF14153.6 KXZ50460.1 - 1.7 8.6 12.8 2 8.3 12.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4366 PF14283.6 KXZ50460.1 - 3.8 7.6 7.4 6.4 6.8 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RR_TM4-6 PF06459.12 KXZ50460.1 - 5.6 6.7 12.0 7.4 6.3 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3391 PF11871.8 KXZ50460.1 - 7.5 7.1 12.7 29 5.2 12.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone_H2A_C PF16211.5 KXZ50461.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ50461.1 - 6.3e-17 62.2 0.0 8.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50461.1 - 3.4e-05 24.0 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CAP_GLY PF01302.25 KXZ50462.1 - 0.0033 17.4 0.1 0.016 15.2 0.1 2.0 1 1 0 1 1 1 1 CAP-Gly domain KOW PF00467.29 KXZ50462.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 KOW motif Pkinase PF00069.25 KXZ50463.1 - 5.6e-44 150.5 0.1 8.9e-29 100.7 0.1 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50463.1 - 9.3e-31 107.0 0.0 1.4e-19 70.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50463.1 - 3.6e-06 26.5 0.1 0.064 12.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KXZ50463.1 - 1.7e-05 23.8 0.1 2.5e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ50463.1 - 0.00035 20.6 0.1 0.00047 20.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ50463.1 - 0.0037 16.6 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_zinc_N PF00107.26 KXZ50464.1 - 2.7e-17 63.0 0.5 2.7e-17 63.0 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXZ50464.1 - 5.3e-10 40.5 2.0 1.8e-06 29.1 0.0 2.9 2 2 1 3 3 3 2 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KXZ50464.1 - 0.0095 15.8 0.4 0.015 15.2 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ADH_N PF08240.12 KXZ50464.1 - 0.037 13.9 1.1 0.072 13.0 0.5 1.8 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain UDPGP PF01704.18 KXZ50465.1 - 3.2e-124 414.8 0.0 3.5e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase CASP_C PF08172.12 KXZ50466.1 - 9.5e-51 172.6 18.6 2.2e-30 105.9 0.0 4.6 4 1 0 5 5 5 2 CASP C terminal DUF1664 PF07889.12 KXZ50466.1 - 0.05 13.6 21.9 0.18 11.9 1.0 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KXZ50466.1 - 0.18 10.5 21.6 0.021 13.5 2.4 3.0 3 0 0 3 3 3 0 AAA domain Phage_GPO PF05929.11 KXZ50466.1 - 0.57 9.8 28.5 0.083 12.5 11.6 3.6 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Plk4_PB2 PF18409.1 KXZ50466.1 - 2.1 9.1 10.0 5.2 7.8 0.4 3.7 3 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 DUF4363 PF14276.6 KXZ50466.1 - 3.1 8.0 12.7 14 5.8 3.8 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) Filament PF00038.21 KXZ50466.1 - 6.2 6.3 44.4 22 4.5 0.7 4.2 2 2 1 3 3 3 0 Intermediate filament protein DUF1254 PF06863.12 KXZ50467.1 - 3.8e-21 75.6 0.2 1.2e-20 74.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 KXZ50467.1 - 9.9e-16 58.2 1.8 1.8e-15 57.3 0.2 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1214) Ammonium_transp PF00909.21 KXZ50468.1 - 1.3e-112 376.4 21.5 1.5e-112 376.2 21.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DEAD PF00270.29 KXZ50469.1 - 2.1e-44 151.4 0.0 3e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ50469.1 - 3e-28 98.4 0.5 1.4e-27 96.3 0.4 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ50469.1 - 0.00028 20.9 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pterin_4a PF01329.19 KXZ50470.1 - 2.1e-20 72.7 1.1 2.2e-20 72.6 0.3 1.4 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase Methyltransf_33 PF10017.9 KXZ50470.1 - 0.0037 16.5 0.0 0.0045 16.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent IF-2 PF11987.8 KXZ50470.1 - 0.0069 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Translation-initiation factor 2 Guanylate_cyc PF00211.20 KXZ50471.1 - 1.5e-32 112.7 0.0 2.2e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2530 PF10745.9 KXZ50471.1 - 0.014 15.6 4.8 0.11 12.7 2.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) CHASE PF03924.13 KXZ50471.1 - 0.043 13.7 1.6 0.085 12.8 0.2 2.0 1 1 1 2 2 2 0 CHASE domain Mito_carr PF00153.27 KXZ50472.1 - 7.8e-59 195.6 3.0 7.7e-22 77.0 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LCIB_C_CA PF18599.1 KXZ50473.1 - 9.1e-70 234.4 0.0 1.2e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Beta_helix PF13229.6 KXZ50475.1 - 1.9e-14 53.8 0.0 1.5e-12 47.6 0.1 3.1 2 1 1 3 3 3 2 Right handed beta helix region Mak10 PF04112.13 KXZ50476.1 - 1.7e-22 79.7 0.1 1.5e-21 76.7 0.1 2.2 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Pkinase PF00069.25 KXZ50478.1 - 1.1e-29 103.6 0.0 3.9e-18 65.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50478.1 - 1.3e-09 37.8 0.0 0.00015 21.2 0.0 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase Carb_anhydrase PF00194.21 KXZ50480.1 - 1.9e-37 129.2 0.0 2.9e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Cyto_heme_lyase PF01265.17 KXZ50480.1 - 0.041 13.5 0.2 0.082 12.5 0.2 1.4 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Carb_anhydrase PF00194.21 KXZ50481.1 - 5e-37 127.8 0.0 8.7e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ntox47 PF15540.6 KXZ50481.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 47 BACON PF13004.7 KXZ50481.1 - 0.26 11.3 3.1 0.15 12.0 0.8 1.8 2 0 0 2 2 2 0 Putative binding domain, N-terminal SURF2 PF05477.11 KXZ50482.1 - 9.7e-22 77.8 13.0 9.7e-22 77.8 13.0 2.8 2 1 0 2 2 2 1 Surfeit locus protein 2 (SURF2) Rav1p_C PF12234.8 KXZ50483.1 - 2.1e-51 175.1 0.0 1.3e-43 149.4 0.0 2.3 2 0 0 2 2 2 2 RAVE protein 1 C terminal LCIB_C_CA PF18599.1 KXZ50484.1 - 1e-69 234.3 0.0 1.3e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases LCIB_C_CA PF18599.1 KXZ50485.1 - 4.6e-66 222.3 0.0 6.9e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Mito_carr PF00153.27 KXZ50486.1 - 9.5e-59 195.3 2.4 4.4e-21 74.6 0.7 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MutS_V PF00488.21 KXZ50488.1 - 2.6e-32 112.4 0.0 1.6e-31 109.8 0.0 2.0 1 1 0 1 1 1 1 MutS domain V FliJ PF02050.16 KXZ50488.1 - 0.03 14.6 1.0 0.052 13.8 1.0 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Prok_Ub PF14454.6 KXZ50488.1 - 0.046 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Ubiquitin LPP PF04728.13 KXZ50488.1 - 1.1 9.7 3.5 2.5 8.5 3.5 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Dynamin_M PF01031.20 KXZ50489.1 - 2.3e-29 102.5 0.0 1.5e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KXZ50489.1 - 4.3e-07 30.1 0.0 8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXZ50489.1 - 0.00024 21.2 0.0 0.00091 19.3 0.0 2.0 1 1 0 1 1 1 1 Dynamin GTPase effector domain Sugarporin_N PF11471.8 KXZ50489.1 - 0.36 10.8 4.4 0.95 9.5 4.4 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Filament PF00038.21 KXZ50491.1 - 0.00088 18.9 58.4 0.069 12.7 35.7 3.2 1 1 2 3 3 3 3 Intermediate filament protein APG6_N PF17675.1 KXZ50491.1 - 0.97 10.0 77.4 0.39 11.2 13.8 5.4 2 1 3 5 5 5 0 Apg6 coiled-coil region DUF812 PF05667.11 KXZ50491.1 - 1.8 7.3 49.3 0.11 11.4 19.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KXZ50491.1 - 3.6 8.0 60.1 1.9 8.9 7.9 4.3 2 1 2 4 4 4 0 Fez1 FlaC_arch PF05377.11 KXZ50491.1 - 4.2 7.9 12.4 12 6.4 0.1 6.1 6 2 0 6 6 6 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 KXZ50491.1 - 8.1 3.8 65.6 0.48 7.9 52.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KXZ50491.1 - 8.3 5.2 56.5 2.3 7.0 8.8 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein Ank_2 PF12796.7 KXZ50492.1 - 5.1e-22 78.3 13.4 1.3e-08 35.3 0.0 5.1 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ50492.1 - 4.5e-19 68.5 7.2 1.8e-07 31.6 0.0 5.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ50492.1 - 1.4e-16 60.1 22.7 0.00013 22.2 0.1 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KXZ50492.1 - 1.6e-14 52.5 11.4 0.042 14.4 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KXZ50492.1 - 2.7e-14 53.0 21.1 0.0032 17.7 0.1 6.9 6 1 1 7 7 7 5 Ankyrin repeats (many copies) TFIID-18kDa PF02269.16 KXZ50494.1 - 7.1e-12 45.2 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit AT_hook PF02178.19 KXZ50494.1 - 0.035 14.0 4.4 0.035 14.0 4.4 2.9 2 0 0 2 2 2 0 AT hook motif Surp PF01805.20 KXZ50495.1 - 3.5e-08 33.3 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Surp module Guanylate_cyc PF00211.20 KXZ50496.1 - 3.3e-53 180.0 0.0 5.4e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 KXZ50496.1 - 0.00014 22.0 1.0 0.21 11.9 0.1 3.9 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 KXZ50496.1 - 0.0048 16.9 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain Helicase_C PF00271.31 KXZ50497.1 - 1.9e-11 44.3 0.0 4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KXZ50497.1 - 2.1e-11 44.0 0.2 5.2e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 KXZ50497.1 - 2.6e-05 24.5 0.0 5.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ50497.1 - 3.7e-05 23.5 0.2 3.7e-05 23.5 0.2 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KXZ50497.1 - 0.00034 20.4 0.0 0.00053 19.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 KXZ50497.1 - 0.0025 17.2 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 KXZ50497.1 - 0.0055 17.1 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXZ50497.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 KXZ50497.1 - 0.034 13.2 0.1 0.54 9.3 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF2075 PF09848.9 KXZ50497.1 - 0.037 13.3 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KXZ50497.1 - 0.05 14.1 0.0 0.077 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ50497.1 - 0.088 13.3 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KXZ50497.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_C1 PF00112.23 KXZ50498.1 - 2.8e-10 40.7 0.5 1.4e-09 38.4 0.1 2.1 1 1 1 2 2 2 1 Papain family cysteine protease EccE PF11203.8 KXZ50498.1 - 0.025 14.9 0.6 0.068 13.5 0.1 1.9 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE KGG PF10685.9 KXZ50498.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.8 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif Mut7-C PF01927.16 KXZ50498.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain Peptidase_S24 PF00717.23 KXZ50500.1 - 2.4e-08 33.8 0.0 4.7e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXZ50500.1 - 3.5e-06 26.8 0.0 0.00046 20.0 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DNA_topoisoIV PF00521.20 KXZ50501.1 - 6.6e-129 430.5 0.0 2e-128 428.9 0.0 1.6 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 KXZ50501.1 - 2.9e-27 93.9 15.4 2.3e-07 30.2 0.1 6.1 6 0 0 6 6 6 4 DNA gyrase C-terminal domain, beta-propeller COX3 PF00510.18 KXZ50502.1 - 3.9e-58 197.3 15.6 4.6e-58 197.1 15.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Glyco_hydro_9 PF00759.19 KXZ50504.1 - 1.1e-56 193.0 9.1 1.1e-55 189.8 9.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 DUF4372 PF14294.6 KXZ50504.1 - 0.25 11.5 0.0 0.51 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) DUF4795 PF16043.5 KXZ50505.1 - 0.013 15.2 0.6 0.013 15.2 0.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) FeoA PF04023.14 KXZ50505.1 - 0.014 15.6 0.0 0.078 13.2 0.0 2.2 2 0 0 2 2 2 0 FeoA domain HOOK PF05622.12 KXZ50505.1 - 0.017 13.3 7.3 0.025 12.8 7.3 1.2 1 0 0 1 1 1 0 HOOK protein Laminin_II PF06009.12 KXZ50505.1 - 0.14 12.2 10.9 0.24 11.4 0.9 3.2 2 2 1 3 3 3 0 Laminin Domain II TolA_bind_tri PF16331.5 KXZ50505.1 - 0.15 12.1 0.1 0.15 12.1 0.1 3.0 3 0 0 3 3 2 0 TolA binding protein trimerisation Prominin PF05478.11 KXZ50505.1 - 0.18 9.8 4.1 0.1 10.5 1.4 1.8 1 1 1 2 2 2 0 Prominin GldM_N PF12081.8 KXZ50505.1 - 0.31 11.1 3.1 3.8 7.6 1.1 3.0 1 1 2 3 3 3 0 GldM N-terminal domain TACC_C PF05010.14 KXZ50505.1 - 0.41 10.4 6.4 0.38 10.5 5.0 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Baculo_PEP_C PF04513.12 KXZ50505.1 - 0.42 10.6 8.6 1.7 8.7 2.2 4.0 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_cc2 PF10267.9 KXZ50505.1 - 0.43 9.7 12.3 0.038 13.1 5.0 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein NPV_P10 PF05531.12 KXZ50505.1 - 0.47 10.9 4.5 48 4.5 0.1 3.8 2 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein cwf21 PF08312.12 KXZ50505.1 - 1.2 9.4 4.0 1.7 8.9 2.1 2.3 2 0 0 2 2 2 0 cwf21 domain SKA2 PF16740.5 KXZ50505.1 - 1.3 8.8 9.6 15 5.4 0.5 3.7 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 GAS PF13851.6 KXZ50505.1 - 2 7.7 13.0 1.2 8.5 1.0 3.0 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KXZ50505.1 - 2.7 6.8 16.9 1.5 7.6 6.0 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein FliD_N PF02465.18 KXZ50505.1 - 3.7 8.3 13.1 0.66 10.7 0.3 3.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.12 KXZ50505.1 - 3.9 7.5 12.3 1.2 9.2 0.8 4.1 3 1 1 5 5 5 0 Protein of unknown function (DUF1664) TBCC_N PF16752.5 KXZ50505.1 - 4 7.9 8.8 3.4 8.1 1.5 2.9 1 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF4200 PF13863.6 KXZ50505.1 - 4.2 7.8 10.4 2.1 8.8 2.4 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Dynactin_p22 PF07426.11 KXZ50505.1 - 5.3 6.9 6.3 1.5 8.7 0.4 2.7 2 1 1 3 3 3 0 Dynactin subunit p22 CENP-F_leu_zip PF10473.9 KXZ50505.1 - 8.2 6.4 17.8 0.76 9.8 2.3 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Methyltransf_16 PF10294.9 KXZ50506.1 - 1.1e-06 28.5 0.0 0.0082 15.9 0.1 2.2 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 KXZ50506.1 - 0.0015 18.0 0.4 0.0023 17.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXZ50506.1 - 0.0049 16.4 0.4 0.01 15.4 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KXZ50506.1 - 0.077 12.8 0.1 6.9 6.5 0.2 2.4 2 0 0 2 2 2 0 Methyltransferase domain Rep_fac-A_C PF08646.10 KXZ50509.1 - 2e-24 86.0 0.0 4.2e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KXZ50509.1 - 1.7e-23 82.4 0.2 8.8e-19 67.2 0.1 3.3 3 0 0 3 3 3 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 KXZ50509.1 - 9.2e-11 41.6 0.4 5.9e-05 23.0 0.1 3.7 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain DUF223 PF02721.14 KXZ50509.1 - 5e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF223 Rep-A_N PF04057.12 KXZ50509.1 - 3.5e-05 23.8 0.3 0.00011 22.1 0.1 2.0 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain GlnD_UR_UTase PF08335.11 KXZ50510.1 - 0.22 11.6 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase PHD PF00628.29 KXZ50511.1 - 9.5e-06 25.4 6.2 1.6e-05 24.7 6.2 1.3 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 KXZ50511.1 - 0.74 9.9 4.7 1.7 8.8 4.7 1.6 1 0 0 1 1 1 0 PHD-finger SPX PF03105.19 KXZ50511.1 - 3 7.7 6.9 0.69 9.8 3.3 1.7 2 0 0 2 2 2 0 SPX domain zf-CSL PF05207.13 KXZ50511.1 - 4.8 7.0 7.8 0.68 9.7 2.3 2.2 2 1 0 2 2 2 0 CSL zinc finger OCRE PF17780.1 KXZ50512.1 - 4.6e-15 55.4 3.3 8e-15 54.6 3.3 1.4 1 0 0 1 1 1 1 OCRE domain SAP PF02037.27 KXZ50512.1 - 0.0096 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 SAP domain Armet PF10208.9 KXZ50512.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding ATP_bind_1 PF03029.17 KXZ50513.1 - 8.7e-84 281.1 0.0 9.8e-84 280.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KXZ50513.1 - 6.1e-05 22.9 0.0 9.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 KXZ50513.1 - 0.00074 20.1 0.0 0.0016 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ50513.1 - 0.0037 17.7 0.0 0.008 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXZ50513.1 - 0.0058 16.9 0.0 0.012 15.9 0.0 1.7 2 1 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 KXZ50513.1 - 0.011 15.6 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 KXZ50513.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KXZ50513.1 - 0.018 15.1 0.0 0.051 13.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXZ50513.1 - 0.02 15.2 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KXZ50513.1 - 0.038 14.5 0.0 0.064 13.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KXZ50513.1 - 0.04 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXZ50513.1 - 0.043 13.9 0.0 0.072 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXZ50513.1 - 0.091 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KXZ50513.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXZ50513.1 - 0.12 12.0 0.0 0.87 9.1 0.0 1.9 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 KXZ50513.1 - 0.13 12.1 0.0 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 KXZ50513.1 - 0.14 11.9 0.0 5 6.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KXZ50513.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TssO PF17561.2 KXZ50514.1 - 0.039 14.1 5.5 0.087 12.9 1.7 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO PKcGMP_CC PF16808.5 KXZ50514.1 - 0.053 13.4 5.4 1.6 8.7 1.3 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HlyD_2 PF12700.7 KXZ50514.1 - 0.069 11.9 4.7 0.087 11.5 4.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Connexin PF00029.19 KXZ50514.1 - 0.18 11.5 4.3 0.41 10.4 4.3 1.7 1 1 0 1 1 1 0 Connexin XRN_M PF17846.1 KXZ50514.1 - 0.23 10.3 4.3 0.3 10.0 4.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain MatE PF01554.18 KXZ50515.1 - 4.7e-28 97.9 24.2 1.4e-16 60.6 7.9 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ50515.1 - 1.5e-05 25.1 6.5 1.5e-05 25.1 6.5 3.3 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Methyltr_RsmB-F PF01189.17 KXZ50517.1 - 1.7e-26 93.1 0.0 3.7e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KXZ50517.1 - 0.00052 20.2 0.0 0.00095 19.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KXZ50517.1 - 0.0012 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ50517.1 - 0.012 16.3 0.0 0.029 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF983 PF06170.12 KXZ50518.1 - 0.018 15.4 1.6 0.022 15.2 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF983) DUF2207 PF09972.9 KXZ50518.1 - 1 8.0 2.5 1.1 8.0 2.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MIB_HERC2 PF06701.13 KXZ50519.1 - 1.2e-39 134.4 39.7 8.3e-11 42.0 7.2 4.4 4 0 0 4 4 4 4 Mib_herc2 ERM PF00769.19 KXZ50519.1 - 0.025 14.4 35.4 0.32 10.8 7.7 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family ATP_bind_3 PF01171.20 KXZ50519.1 - 0.071 12.9 5.1 0.14 11.9 5.1 1.4 1 0 0 1 1 1 0 PP-loop family MAP7 PF05672.11 KXZ50519.1 - 1.8 8.3 32.5 0.44 10.2 4.1 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family AP2 PF00847.20 KXZ50519.1 - 2.4 8.5 14.3 27 5.1 0.1 4.5 4 0 0 4 4 4 0 AP2 domain DUF3458_C PF17432.2 KXZ50521.1 - 2e-114 382.3 0.4 2.8e-114 381.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 KXZ50521.1 - 1.7e-50 171.7 0.0 2.3e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 KXZ50521.1 - 1.3e-28 99.3 0.0 3.2e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M61 PF05299.12 KXZ50521.1 - 0.043 14.2 0.2 0.19 12.1 0.2 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase TEP1_N PF05386.11 KXZ50521.1 - 0.058 13.0 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain WD40 PF00400.32 KXZ50523.1 - 3.7e-31 106.7 11.3 2e-06 28.4 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ50523.1 - 1.6e-16 60.4 0.6 0.00048 20.4 0.0 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ50523.1 - 5.6e-07 28.8 0.2 0.0042 16.1 0.0 3.4 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXZ50523.1 - 6.5e-05 22.4 0.1 0.0066 15.8 0.0 2.5 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KXZ50523.1 - 0.0001 20.8 0.0 0.14 10.4 0.0 2.5 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KXZ50523.1 - 0.0028 16.4 0.6 1.2 7.7 0.0 3.8 3 1 1 5 5 5 1 Nucleoporin Nup120/160 DUF3931 PF13082.6 KXZ50523.1 - 0.059 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) DUF810 PF05664.11 KXZ50525.1 - 2.4e-40 138.8 0.0 8.7e-24 84.0 0.0 2.3 2 0 0 2 2 2 2 Plant family of unknown function (DUF810) MatE PF01554.18 KXZ50525.1 - 7e-23 81.0 25.4 9.9e-15 54.6 9.8 2.7 3 0 0 3 3 3 2 MatE Membr_traf_MHD PF10540.9 KXZ50525.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain BTB PF00651.31 KXZ50526.1 - 8.9e-07 29.1 0.0 0.00084 19.5 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain Pkinase PF00069.25 KXZ50527.1 - 3.6e-31 108.5 0.0 4.9e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50527.1 - 1.3e-25 90.1 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ50527.1 - 0.0032 16.3 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ50527.1 - 0.016 15.1 2.2 0.065 13.2 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ50528.1 - 3.9e-28 98.5 0.0 5.2e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50528.1 - 2.4e-24 86.0 0.0 2.9e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ50528.1 - 0.00033 19.6 0.0 0.00041 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ50528.1 - 0.0079 16.1 0.8 0.084 12.8 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXZ50528.1 - 0.033 13.2 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dsh_C PF12316.8 KXZ50531.1 - 0.34 11.3 12.5 0.41 11.0 12.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2508 PF10704.9 KXZ50531.1 - 0.64 10.2 3.7 0.57 10.4 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) XRN_M PF17846.1 KXZ50531.1 - 8.4 5.2 7.8 10 4.9 7.8 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF4407 PF14362.6 KXZ50531.1 - 8.9 5.6 12.0 11 5.3 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 KXZ50532.1 - 8e-40 136.9 0.0 1.1e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50532.1 - 6.9e-34 117.3 0.0 8.9e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ50532.1 - 0.0026 16.6 0.0 0.0034 16.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ50532.1 - 0.023 14.7 4.4 0.027 14.4 1.5 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Macoilin PF09726.9 KXZ50533.1 - 0.05 12.2 0.3 0.059 11.9 0.3 1.0 1 0 0 1 1 1 0 Macoilin family ATG16 PF08614.11 KXZ50533.1 - 0.082 13.1 5.4 0.1 12.8 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KXZ50533.1 - 0.27 10.1 1.9 0.3 9.9 1.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 KXZ50533.1 - 0.3 11.8 7.8 0.22 12.2 1.2 2.6 1 1 1 2 2 2 0 SlyX Phycobilisome PF00502.19 KXZ50533.1 - 0.52 10.2 4.5 0.81 9.6 0.5 2.1 2 0 0 2 2 2 0 Phycobilisome protein TolA_bind_tri PF16331.5 KXZ50533.1 - 0.7 10.0 8.4 2.1e+02 2.1 8.4 2.7 1 1 0 1 1 1 0 TolA binding protein trimerisation AAA_33 PF13671.6 KXZ50534.1 - 2.4e-07 31.0 0.1 1.6e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXZ50534.1 - 0.00022 21.8 0.0 0.00074 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXZ50534.1 - 0.00032 21.0 0.3 0.0014 18.9 0.1 2.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KXZ50534.1 - 0.0006 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 KXZ50534.1 - 0.00099 19.0 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KXZ50534.1 - 0.0027 17.7 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 KXZ50534.1 - 0.0094 16.5 0.1 0.018 15.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KXZ50534.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 KXZ50534.1 - 0.018 15.0 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 KXZ50534.1 - 0.019 15.3 1.7 0.034 14.5 0.1 2.2 3 0 0 3 3 2 0 AAA ATPase domain RuvB_N PF05496.12 KXZ50534.1 - 0.042 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain G-alpha PF00503.20 KXZ50534.1 - 0.046 12.9 0.0 0.07 12.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 KXZ50534.1 - 0.057 13.8 0.5 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KXZ50534.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Cytidylate kinase T2SSE PF00437.20 KXZ50534.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 KXZ50534.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ50534.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXZ50534.1 - 0.17 11.6 0.3 0.42 10.3 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 KXZ50534.1 - 0.21 11.6 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Snf7 PF03357.21 KXZ50536.1 - 8.6e-43 145.9 22.0 8.6e-43 145.9 22.0 1.4 1 1 1 2 2 2 1 Snf7 CdvA PF18822.1 KXZ50536.1 - 0.013 15.3 5.0 0.013 15.3 5.0 2.7 2 1 0 2 2 2 0 CdvA-like coiled-coil domain GAS PF13851.6 KXZ50536.1 - 0.088 12.2 15.9 0.053 12.9 11.1 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Ist1 PF03398.14 KXZ50536.1 - 0.12 12.3 7.3 0.17 11.8 7.3 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway ACP_PD PF04336.12 KXZ50536.1 - 1.6 9.2 4.9 1.8 9.0 1.0 2.4 1 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase YlqD PF11068.8 KXZ50536.1 - 2.4 8.5 14.0 0.48 10.8 6.1 2.2 1 1 1 2 2 2 0 YlqD protein ATC_hydrolase PF14196.6 KXZ50536.1 - 3.2 8.5 6.4 6.3 7.6 0.0 2.9 1 1 2 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Methyltransf_4 PF02390.17 KXZ50537.1 - 3e-27 95.2 0.0 6e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 KXZ50537.1 - 0.042 13.7 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXZ50537.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M6 PF05547.11 KXZ50538.1 - 0.078 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Reprolysin_5 PF13688.6 KXZ50538.1 - 0.087 13.0 0.1 0.26 11.4 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 KXZ50538.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.9 KXZ50538.1 - 4.6 6.1 5.2 5 6.0 0.2 2.1 2 0 0 2 2 2 0 Peptidase M66 CbiX PF01903.17 KXZ50539.1 - 1.5e-30 105.7 0.1 1.9e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 KXZ50539.1 - 4.2e-06 26.3 0.0 5.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Glyoxalase_6 PF18029.1 KXZ50539.1 - 0.023 15.5 0.2 0.1 13.4 0.2 1.9 2 0 0 2 2 2 0 Glyoxalase-like domain Costars PF14705.6 KXZ50539.1 - 0.045 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Costars Ferrochelatase PF00762.19 KXZ50539.1 - 0.097 11.7 0.0 0.3 10.1 0.0 1.4 1 1 0 1 1 1 0 Ferrochelatase MFS_MOT1 PF16983.5 KXZ50540.1 - 1.6e-24 86.5 15.1 4.6e-20 72.1 7.1 2.6 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily MFS_MOT1 PF16983.5 KXZ50541.1 - 0.0023 18.3 4.5 0.0023 18.3 4.5 2.1 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF543 PF04418.12 KXZ50541.1 - 1.2 9.1 3.8 7.9 6.5 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF543) Ion_trans PF00520.31 KXZ50543.1 - 1.3e-05 24.6 9.6 2e-05 24.0 9.6 1.2 1 0 0 1 1 1 1 Ion transport protein BCCT PF02028.17 KXZ50544.1 - 0.022 13.2 0.2 0.022 13.2 0.2 2.3 3 0 0 3 3 3 0 BCCT, betaine/carnitine/choline family transporter DUF2645 PF10840.8 KXZ50544.1 - 0.44 11.2 0.1 0.44 11.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2645) Ank_2 PF12796.7 KXZ50545.1 - 1.2e-09 38.6 2.8 0.023 15.3 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ50545.1 - 6.6e-06 26.6 6.4 4.5 8.0 0.1 5.2 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50545.1 - 3.1e-05 24.0 1.9 1.1 10.0 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KXZ50545.1 - 0.12 12.7 2.2 2.9 8.3 0.1 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) ERAP1_C PF11838.8 KXZ50545.1 - 0.16 11.5 1.6 0.37 10.3 1.2 1.7 1 1 0 1 1 1 0 ERAP1-like C-terminal domain Tautomerase PF01361.21 KXZ50546.1 - 1e-05 25.4 0.8 0.0015 18.4 0.2 2.2 2 0 0 2 2 2 2 Tautomerase enzyme MIF PF01187.18 KXZ50546.1 - 0.00027 21.2 0.1 0.00031 21.0 0.1 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase_2 PF14552.6 KXZ50546.1 - 0.00094 19.2 0.0 0.0073 16.4 0.0 2.0 1 1 1 2 2 2 1 Tautomerase enzyme Tautomerase_3 PF14832.6 KXZ50546.1 - 0.024 14.8 0.0 0.045 14.0 0.0 1.4 1 1 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme DUF3181 PF11378.8 KXZ50547.1 - 4e-26 91.1 0.0 6.1e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3181) TENA_THI-4 PF03070.16 KXZ50549.1 - 1.1e-28 100.5 0.0 5.7e-28 98.2 0.0 1.8 1 1 0 1 1 1 1 TENA/THI-4/PQQC family HSP70 PF00012.20 KXZ50550.1 - 2.8e-270 897.7 8.5 3.2e-270 897.5 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ50550.1 - 1.6e-13 50.2 1.2 4.2e-11 42.3 0.1 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KXZ50550.1 - 0.0048 17.3 5.8 7.1 7.1 0.0 3.9 3 1 0 3 3 3 2 Cell division protein FtsA Abhydrolase_8 PF06259.12 KXZ50550.1 - 0.023 14.4 1.0 0.048 13.3 1.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase TetR_C_25 PF17933.1 KXZ50550.1 - 0.087 13.1 0.3 0.41 11.0 0.2 2.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DbpA PF03880.15 KXZ50550.1 - 0.13 12.3 0.0 0.5 10.4 0.0 2.0 1 0 0 1 1 1 0 DbpA RNA binding domain Cytochrom_B562 PF07361.11 KXZ50550.1 - 1.1 9.9 11.0 0.8 10.4 8.4 2.0 2 0 0 2 2 2 0 Cytochrome b562 DUF1336 PF07059.12 KXZ50551.1 - 4.7e-49 167.5 0.0 5.9e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) CCDC144C PF14915.6 KXZ50552.1 - 0.055 12.6 1.0 0.079 12.1 1.0 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region ABC_tran PF00005.27 KXZ50553.1 - 1.4e-16 61.3 0.0 2.1e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXZ50553.1 - 8.1e-08 31.9 8.5 1.2e-07 31.4 8.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KXZ50553.1 - 0.00017 21.5 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KXZ50553.1 - 0.00032 20.4 0.1 0.00067 19.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 KXZ50553.1 - 0.0015 18.5 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXZ50553.1 - 0.0023 18.4 0.1 0.0037 17.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXZ50553.1 - 0.023 14.9 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ50553.1 - 0.054 14.0 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXZ50553.1 - 0.062 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ50553.1 - 0.067 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KXZ50553.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_21 PF13304.6 KXZ50553.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KXZ50553.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Phage_holin_3_6 PF07332.11 KXZ50553.1 - 0.19 11.8 4.3 0.45 10.6 4.3 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Acyltransferase PF01553.21 KXZ50554.1 - 1.4e-12 47.4 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Sulfatase PF00884.23 KXZ50556.1 - 8.6e-65 219.1 0.5 1.1e-64 218.8 0.5 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXZ50556.1 - 3.5e-05 24.0 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Pyr_redox_2 PF07992.14 KXZ50557.1 - 3.1e-08 33.2 0.0 5.7e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sulfatase PF00884.23 KXZ50558.1 - 2.3e-63 214.5 0.4 3.1e-63 214.0 0.4 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXZ50558.1 - 3.6e-06 27.2 0.0 9.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) partial_CstF PF15861.5 KXZ50560.1 - 0.021 14.6 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Fuseless PF15993.5 KXZ50563.1 - 0.0006 19.1 1.8 0.00084 18.6 1.8 1.1 1 0 0 1 1 1 1 Fuseless BTB PF00651.31 KXZ50564.1 - 0.012 15.9 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain zf-MYND PF01753.18 KXZ50565.1 - 1.5e-05 25.0 2.2 3.1e-05 24.0 2.2 1.5 1 0 0 1 1 1 1 MYND finger DUF3437 PF11919.8 KXZ50567.1 - 0.0057 16.5 0.1 0.034 14.1 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3437) LRR_8 PF13855.6 KXZ50568.1 - 1.5 8.6 5.5 11 5.9 0.2 3.9 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KXZ50568.1 - 3.5 8.2 7.6 1.7 9.2 0.8 4.0 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 KXZ50569.1 - 0.0099 16.5 0.1 0.021 15.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ50569.1 - 0.1 13.2 0.2 3.9 8.4 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Pkinase PF00069.25 KXZ50571.1 - 2.9e-71 239.9 0.0 3.4e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50571.1 - 4.3e-43 147.5 0.0 5.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50571.1 - 3.5e-06 26.5 0.0 0.00018 20.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 KXZ50571.1 - 0.028 13.5 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 V_ATPase_I PF01496.19 KXZ50572.1 - 7.7e-173 576.5 0.0 1.4e-128 430.1 0.4 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family EzrA PF06160.12 KXZ50572.1 - 0.0037 15.5 0.1 0.0053 15.0 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 KXZ50572.1 - 0.059 13.6 1.6 0.13 12.5 1.6 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF4600 PF15372.6 KXZ50572.1 - 0.065 13.7 0.3 0.1 13.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) SlyX PF04102.12 KXZ50572.1 - 0.067 13.8 0.9 4.7 7.9 0.3 2.4 2 0 0 2 2 2 0 SlyX Caveolin PF01146.17 KXZ50572.1 - 0.63 10.0 3.3 2 8.4 3.3 1.8 1 0 0 1 1 1 0 Caveolin WD40 PF00400.32 KXZ50573.1 - 3.4e-17 62.5 0.1 1.9e-06 28.5 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ50573.1 - 6.7e-06 26.3 0.0 0.02 15.2 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ50573.1 - 0.039 12.9 0.0 3.1 6.7 0.0 2.8 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BTB PF00651.31 KXZ50574.1 - 4.9e-19 68.6 0.0 7.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3110 PF11360.8 KXZ50575.1 - 3.7e-21 75.1 0.0 5e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) PGP_phosphatase PF09419.10 KXZ50576.1 - 3.8e-38 130.8 0.0 4.6e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KXZ50576.1 - 7.8e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like GAF_2 PF13185.6 KXZ50576.1 - 0.00073 19.8 0.1 0.037 14.3 0.0 2.2 2 0 0 2 2 2 1 GAF domain HAD_2 PF13419.6 KXZ50576.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 KXZ50577.1 - 6.3e-20 70.8 0.0 3.2e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.17 KXZ50578.1 - 2.6e-39 135.1 0.0 3.6e-18 65.8 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50578.1 - 6.9e-35 120.7 0.0 2.4e-14 53.4 0.0 3.4 4 0 0 4 4 4 3 Protein kinase domain APH PF01636.23 KXZ50578.1 - 5.9e-05 23.1 0.9 0.00045 20.2 0.9 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 KXZ50578.1 - 0.028 14.6 0.1 0.062 13.5 0.1 1.5 1 0 0 1 1 1 0 ABC1 family Pkinase_Tyr PF07714.17 KXZ50579.1 - 5.4e-39 134.0 0.0 3.6e-29 101.8 0.1 3.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50579.1 - 1.6e-35 122.7 0.0 5.8e-35 120.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain PB1 PF00564.24 KXZ50579.1 - 3.8e-06 26.7 0.0 7.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain DUF3104 PF11302.8 KXZ50581.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Ion_trans PF00520.31 KXZ50583.1 - 4.5e-11 42.4 2.4 7.7e-11 41.7 2.4 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KXZ50583.1 - 4.7e-07 30.3 0.0 0.00023 21.7 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ50583.1 - 8e-06 26.1 0.3 0.2 12.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXZ50583.1 - 1.7e-05 25.0 1.6 0.032 14.5 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 KXZ50583.1 - 3.2e-05 22.8 3.0 3.2e-05 22.8 3.0 2.0 1 1 1 2 2 2 1 Polycystin cation channel Ank_4 PF13637.6 KXZ50583.1 - 4.5e-05 23.9 1.4 0.068 13.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50583.1 - 0.0013 19.0 0.3 11 7.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat PSII_Pbs27 PF13326.6 KXZ50584.1 - 1.1e-29 103.5 0.1 5.4e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Photosystem II Pbs27 PsbQ PF05757.11 KXZ50584.1 - 0.25 11.1 4.1 0.39 10.4 3.6 1.5 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Exo_endo_phos PF03372.23 KXZ50586.1 - 5.8e-15 55.5 0.0 3.1e-13 49.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C2 PF00648.21 KXZ50588.1 - 6.5e-40 137.0 0.0 2.9e-34 118.4 0.0 2.1 1 1 1 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 KXZ50588.1 - 2.8e-26 92.5 0.0 2.4e-10 40.9 0.0 4.7 4 1 0 4 4 4 4 Calpain large subunit, domain III UPF0029 PF01205.19 KXZ50590.1 - 1.4e-26 92.8 0.0 2.1e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 KXZ50590.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) PTH2 PF01981.16 KXZ50591.1 - 3.7e-11 43.3 0.0 4.2e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Tox-REase-7 PF15649.6 KXZ50591.1 - 0.002 18.4 0.0 0.0023 18.2 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 7 DUF3140 PF11338.8 KXZ50591.1 - 0.089 13.2 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) KAP PF05804.12 KXZ50592.1 - 8.5e-186 619.2 12.0 3.4e-185 617.2 12.0 1.7 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) UPF0147 PF03685.13 KXZ50592.1 - 0.031 14.3 0.5 0.69 10.0 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) Arm PF00514.23 KXZ50592.1 - 0.041 14.0 0.7 67 3.7 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KXZ50592.1 - 0.054 13.5 3.6 1.4 9.0 0.1 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 KXZ50592.1 - 0.24 11.8 2.8 4.1 7.9 0.1 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Glutaredoxin2_C PF04399.13 KXZ50592.1 - 0.66 9.8 4.4 11 5.8 0.0 3.9 4 1 1 5 5 5 0 Glutaredoxin 2, C terminal domain Med3 PF11593.8 KXZ50592.1 - 2.7 7.1 14.7 4.2 6.4 14.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ank_2 PF12796.7 KXZ50593.1 - 3.5e-137 447.3 21.5 3.4e-17 62.8 0.1 17.0 7 5 10 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ50593.1 - 2.3e-110 359.7 48.4 5.3e-08 33.3 0.1 22.1 13 5 11 24 24 24 20 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ50593.1 - 1.5e-102 334.3 67.5 1.4e-11 44.4 0.1 23.2 13 7 10 24 24 24 22 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50593.1 - 1.2e-95 301.8 56.1 0.00012 22.2 0.0 30.3 30 1 1 31 31 31 24 Ankyrin repeat Ank PF00023.30 KXZ50593.1 - 8.7e-90 291.6 125.7 5.5e-05 23.4 0.3 30.0 30 1 0 30 30 30 24 Ankyrin repeat NapD PF03927.13 KXZ50593.1 - 0.16 12.0 0.1 7.8 6.6 0.0 2.7 2 0 0 2 2 2 0 NapD protein DUF3707 PF12499.8 KXZ50596.1 - 1.9e-23 83.6 0.0 3.4e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 Pherophorin Kinesin PF00225.23 KXZ50597.1 - 1.7e-118 395.3 0.2 4.1e-118 394.1 0.0 1.8 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ50597.1 - 3.4e-25 88.7 3.1 7.9e-25 87.5 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding Cbl_N PF02262.16 KXZ50597.1 - 0.016 15.2 0.1 0.16 12.0 0.0 2.7 2 1 1 3 3 3 0 CBL proto-oncogene N-terminal domain 1 V_ATPase_I PF01496.19 KXZ50597.1 - 0.18 9.7 17.5 0.25 9.2 17.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RbsD_FucU PF05025.13 KXZ50597.1 - 0.41 11.1 3.8 1.3 9.4 3.8 1.9 1 0 0 1 1 1 0 RbsD / FucU transport protein family AAA_13 PF13166.6 KXZ50597.1 - 3.2 6.3 24.9 6.4 5.3 24.9 1.5 1 0 0 1 1 1 0 AAA domain Kinesin_assoc PF16183.5 KXZ50597.1 - 7.3 6.7 14.3 36 4.4 13.5 2.3 1 1 0 1 1 1 0 Kinesin-associated ABC_tran PF00005.27 KXZ50598.1 - 7.8e-15 55.6 0.0 6.8e-14 52.5 0.0 2.6 3 1 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KXZ50598.1 - 4e-08 33.4 1.0 0.0026 17.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TPR_1 PF00515.28 KXZ50598.1 - 8.6e-07 28.5 19.2 0.0044 16.8 1.5 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ50598.1 - 0.00022 21.4 34.1 0.00088 19.5 0.6 4.8 3 2 0 3 3 3 1 Tetratricopeptide repeat AAA_25 PF13481.6 KXZ50598.1 - 0.0047 16.5 1.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_10 PF13374.6 KXZ50598.1 - 0.017 15.0 0.2 0.017 15.0 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_29 PF13555.6 KXZ50598.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_7 PF13176.6 KXZ50598.1 - 0.073 13.1 8.6 0.18 11.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_23 PF13476.6 KXZ50598.1 - 0.32 11.5 0.2 0.6 10.6 0.2 1.4 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 KXZ50598.1 - 0.94 9.9 6.0 5.6 7.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ50598.1 - 7.1 7.0 39.4 0.18 12.0 2.2 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF2358 PF10184.9 KXZ50599.1 - 7.7e-22 77.7 0.1 1.1e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) EMP24_GP25L PF01105.24 KXZ50600.1 - 5.2e-26 91.7 0.0 6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FAD_oxidored PF12831.7 KXZ50600.1 - 0.0089 15.4 0.3 0.01 15.2 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase SseC PF04888.12 KXZ50601.1 - 2.5e-05 24.1 11.6 0.59 9.7 11.6 2.5 1 1 0 1 1 1 1 Secretion system effector C (SseC) like family YpjP PF14005.6 KXZ50601.1 - 0.00038 20.5 1.3 0.85 9.7 0.1 3.4 1 1 2 3 3 3 2 YpjP-like protein DUF445 PF04286.12 KXZ50601.1 - 0.0087 15.9 1.5 0.013 15.3 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1997 PF09366.10 KXZ50601.1 - 0.014 15.5 0.1 26 4.9 0.0 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1997) Rap1a PF18602.1 KXZ50601.1 - 0.17 12.2 4.8 24 5.3 0.1 4.0 1 1 3 4 4 4 0 Rap1a immunity proteins Bcl-2 PF00452.19 KXZ50601.1 - 0.21 12.3 2.2 9.5 7.0 0.2 2.9 1 1 1 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family PIN_8 PF18476.1 KXZ50601.1 - 0.36 10.7 3.0 0.56 10.0 3.0 1.3 1 1 0 1 1 1 0 PIN like domain FolB PF02152.18 KXZ50601.1 - 0.68 10.5 4.5 10 6.7 0.2 3.8 1 1 1 2 2 2 0 Dihydroneopterin aldolase HK97-gp10_like PF04883.12 KXZ50601.1 - 1.2 10.1 23.3 57 4.8 1.0 5.2 1 1 2 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component ATC_hydrolase PF14196.6 KXZ50601.1 - 4.8 7.9 17.7 27 5.5 3.2 3.7 1 1 3 4 4 4 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase YqzM PF14141.6 KXZ50602.1 - 0.017 15.2 0.2 0.028 14.5 0.2 1.4 1 0 0 1 1 1 0 YqzM-like protein Ribosomal_S15 PF00312.22 KXZ50603.1 - 4.8e-23 81.2 0.0 1.1e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 UPF0016 PF01169.19 KXZ50604.1 - 9.6e-44 147.6 23.0 3.8e-22 78.4 3.6 2.9 2 1 1 3 3 3 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KXZ50604.1 - 0.0039 16.9 6.3 0.0039 16.9 6.3 3.0 2 1 1 3 3 3 2 Putative manganese efflux pump adh_short PF00106.25 KXZ50605.1 - 5.3e-21 75.0 0.1 6.3e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ50605.1 - 8.1e-14 51.7 0.1 1e-13 51.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ50605.1 - 1.4e-08 34.8 0.1 1.8e-08 34.5 0.1 1.0 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KXZ50605.1 - 0.027 14.4 0.3 0.043 13.7 0.1 1.4 1 1 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.21 KXZ50605.1 - 0.031 13.8 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ50605.1 - 0.069 12.5 0.0 0.079 12.3 0.0 1.0 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RtcR PF06956.11 KXZ50605.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase DOPA_dioxygen PF08883.11 KXZ50605.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family adh_short PF00106.25 KXZ50606.1 - 3.7e-09 36.3 0.1 5.7e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ50606.1 - 2.6e-08 33.7 0.1 5.6e-08 32.6 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PUB PF09409.10 KXZ50607.1 - 9e-13 48.0 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 PUB domain WD40 PF00400.32 KXZ50608.1 - 2.4e-25 88.3 18.1 0.00012 22.8 0.2 8.4 8 1 1 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ50608.1 - 1.8e-19 69.8 0.0 0.1 12.9 0.0 7.5 2 2 6 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KXZ50608.1 - 3.4e-19 69.1 0.0 5.3e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KXZ50608.1 - 1.5e-07 30.7 1.3 2.1 7.2 0.1 4.8 3 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXZ50608.1 - 0.0028 17.0 0.1 33 3.7 0.0 4.5 2 2 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KXZ50608.1 - 0.0065 15.6 0.0 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) eIF2A PF08662.11 KXZ50608.1 - 0.055 13.3 0.0 4.5 7.1 0.0 2.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KXZ50608.1 - 0.067 13.2 2.3 35 4.5 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KXZ50608.1 - 0.11 12.2 1.7 44 3.9 0.0 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature ATP-synt_ab PF00006.25 KXZ50609.1 - 1.8e-70 236.9 0.0 3.2e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KXZ50609.1 - 2.7e-40 137.6 0.1 4.7e-40 136.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KXZ50609.1 - 5.6e-16 58.8 0.6 1.6e-15 57.4 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 KXZ50609.1 - 0.0033 17.5 0.1 0.011 15.9 0.1 1.9 1 1 1 2 2 2 1 HAS barrel domain AAA_33 PF13671.6 KXZ50610.1 - 1.7e-14 54.2 1.6 1.7e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXZ50610.1 - 0.00089 18.6 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 KXZ50610.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 KXZ50610.1 - 0.034 14.1 0.1 0.095 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ50610.1 - 0.035 14.4 0.0 0.073 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain TALPID3 PF15324.6 KXZ50610.1 - 0.17 9.6 1.6 0.23 9.1 1.6 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Vir_act_alpha_C PF10400.9 KXZ50610.1 - 0.2 12.4 4.1 0.91 10.2 0.1 3.0 3 0 0 3 3 3 0 Virulence activator alpha C-term TFIIA PF03153.13 KXZ50610.1 - 0.78 9.7 6.0 1 9.3 6.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LEA_5 PF00477.17 KXZ50611.1 - 3.5e-61 204.4 76.1 2.4e-15 56.9 9.8 4.3 1 1 4 5 5 5 5 Small hydrophilic plant seed protein CW_7 PF08230.11 KXZ50611.1 - 0.0052 16.5 20.5 7.3 6.4 0.1 7.0 7 0 0 7 7 7 3 CW_7 repeat KGG PF10685.9 KXZ50611.1 - 0.0096 16.2 32.4 13 6.2 1.0 7.7 7 0 0 7 7 7 6 Stress-induced bacterial acidophilic repeat motif AT_hook PF02178.19 KXZ50611.1 - 0.073 13.0 0.4 0.073 13.0 0.4 2.1 2 0 0 2 2 2 0 AT hook motif Hist_deacetyl PF00850.19 KXZ50612.1 - 1.9e-82 277.2 0.0 2.4e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain YL1 PF05764.13 KXZ50613.1 - 0.0012 19.0 5.1 0.0017 18.5 5.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 KXZ50613.1 - 0.073 11.3 8.5 0.1 10.8 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXZ50613.1 - 0.076 11.3 4.2 0.09 11.1 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 KXZ50613.1 - 0.15 11.9 6.6 0.25 11.1 6.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTPRCAP PF15713.5 KXZ50613.1 - 1.6 9.0 13.5 3.7 7.8 13.5 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 KXZ50613.1 - 1.7 6.7 16.4 2.2 6.3 16.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 KXZ50613.1 - 2.2 8.0 9.1 3.9 7.2 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.12 KXZ50613.1 - 3.1 7.0 12.1 4.3 6.6 12.1 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KXZ50613.1 - 3.6 7.2 6.6 6.7 6.4 6.6 1.4 1 0 0 1 1 1 0 FAM176 family Astro_capsid_p PF12226.8 KXZ50613.1 - 8.5 5.4 12.9 13 4.9 12.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ank_5 PF13857.6 KXZ50614.1 - 3.8e-06 27.1 1.1 5.5e-06 26.6 0.9 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ50614.1 - 4.9e-06 27.0 0.1 0.012 16.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ50614.1 - 1.6e-05 25.1 1.0 2.1e-05 24.8 0.1 1.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KXZ50614.1 - 7.1e-05 23.3 0.0 7.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ50614.1 - 0.00018 21.7 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KXZ50615.1 - 5.1e-15 55.8 0.1 6e-10 39.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ50615.1 - 1.8e-14 53.4 0.0 0.00057 20.2 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ50615.1 - 3.5e-13 49.5 0.2 1.7e-05 25.0 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50615.1 - 8e-12 44.3 0.1 0.0077 16.7 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXZ50615.1 - 1.2e-11 44.9 0.1 1.6e-05 25.4 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ50616.1 - 1.7e-26 91.9 7.1 5.6e-10 39.3 0.2 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ50616.1 - 4.4e-24 83.8 5.1 1.1e-05 25.6 0.1 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 KXZ50616.1 - 9.3e-23 80.6 0.2 3.3e-10 40.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ50616.1 - 4.2e-20 71.8 1.6 1.7e-09 38.0 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50616.1 - 1.1e-17 62.3 0.6 0.00029 21.1 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat DUF1659 PF07872.11 KXZ50617.1 - 0.027 14.1 0.1 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) zf-HC3 PF16827.5 KXZ50617.1 - 0.14 12.3 0.8 3.3 8.0 0.1 2.4 2 0 0 2 2 2 0 zinc-finger Hexokinase_1 PF00349.21 KXZ50618.1 - 3.5e-56 190.3 0.0 4.5e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KXZ50618.1 - 4.7e-46 157.2 0.0 1.5e-45 155.6 0.0 1.8 1 1 0 1 1 1 1 Hexokinase Ank_2 PF12796.7 KXZ50619.1 - 9e-60 199.2 0.2 3e-16 59.8 0.0 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ50619.1 - 5.1e-36 122.6 0.7 7.1e-10 39.2 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ50619.1 - 1.9e-32 110.9 3.5 3.2e-11 43.2 0.2 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50619.1 - 2.3e-27 92.0 0.0 2.2e-06 27.5 0.0 6.4 6 1 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXZ50619.1 - 2e-26 91.2 3.6 6e-07 29.6 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Pkinase PF00069.25 KXZ50621.1 - 1.1e-32 113.4 0.0 4.5e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50621.1 - 2.2e-29 102.6 0.0 1.8e-24 86.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ50621.1 - 0.0021 16.9 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ50621.1 - 0.005 16.8 0.2 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ50621.1 - 0.015 14.7 0.0 0.026 13.8 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXZ50621.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ50622.1 - 2.9e-08 33.4 0.7 0.0033 16.8 0.1 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50622.1 - 3.9e-05 23.1 1.0 0.31 10.3 0.4 2.9 2 1 1 3 3 3 3 Protein tyrosine kinase Myb_DNA-binding PF00249.31 KXZ50625.1 - 8e-09 35.6 0.1 1.5e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ50625.1 - 4.2e-05 23.7 0.6 0.00011 22.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain PLAC8 PF04749.17 KXZ50626.1 - 2e-17 64.0 9.7 2.8e-17 63.5 9.7 1.2 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KXZ50627.1 - 1.4e-13 51.7 6.2 1.7e-13 51.4 6.2 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 KXZ50628.1 - 9.9e-16 58.6 8.6 1.4e-15 58.1 8.6 1.2 1 0 0 1 1 1 1 PLAC8 family Mannosyl_trans3 PF11051.8 KXZ50629.1 - 0.025 13.9 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative HCV_NS4b PF01001.19 KXZ50629.1 - 0.03 13.9 0.4 0.041 13.5 0.4 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b RPN13_C PF16550.5 KXZ50630.1 - 0.018 15.2 0.8 0.06 13.5 0.2 2.1 3 0 0 3 3 3 0 UCH-binding domain CRISPR_Cse2 PF09485.10 KXZ50630.1 - 0.025 15.1 2.3 0.035 14.6 0.4 2.0 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) PA28_alpha PF02251.18 KXZ50630.1 - 0.11 12.5 0.4 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit BAR PF03114.18 KXZ50630.1 - 0.18 11.4 0.2 0.27 10.8 0.2 1.2 1 0 0 1 1 1 0 BAR domain NFACT-R_1 PF05670.13 KXZ50631.1 - 9.6e-33 113.1 0.0 1.5e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KXZ50631.1 - 1.9e-26 92.1 0.0 4.4e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 NFACT protein C-terminal domain FbpA PF05833.11 KXZ50632.1 - 2.6e-14 52.8 0.0 1.3e-13 50.6 0.0 1.7 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Peptidase_M32 PF02074.15 KXZ50633.1 - 9.5e-159 529.3 0.0 2.4e-157 524.6 0.0 2.0 1 1 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase GLTT PF01744.20 KXZ50633.1 - 0.42 10.4 1.5 26 4.7 0.1 2.7 2 0 0 2 2 2 0 GLTT repeat (6 copies) Paramyxo_P_V_N PF13825.6 KXZ50634.1 - 0.019 14.4 2.6 0.022 14.2 2.6 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus F-box-like PF12937.7 KXZ50635.1 - 0.00036 20.4 0.2 0.0007 19.4 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ50635.1 - 0.00075 19.3 0.1 0.0017 18.2 0.0 1.6 2 0 0 2 2 2 1 F-box domain DUF3168 PF11367.8 KXZ50635.1 - 0.035 14.3 2.2 0.035 14.3 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) Coatomer_WDAD PF04053.14 KXZ50636.1 - 2e-155 518.3 0.0 3e-155 517.6 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KXZ50636.1 - 8.3e-30 102.4 0.6 6.4e-07 30.0 0.1 6.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ50636.1 - 0.0003 21.0 0.1 0.52 10.6 0.0 4.9 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_phi PF04931.13 KXZ50636.1 - 5.5 4.9 14.3 7.9 4.4 14.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tubulin PF00091.25 KXZ50637.1 - 1.2e-42 146.3 0.2 2.2e-42 145.5 0.2 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KXZ50637.1 - 8.9e-26 90.0 0.8 2.5e-25 88.6 0.8 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Ribosomal_60s PF00428.19 KXZ50637.1 - 2.1 9.0 17.9 2.4 8.8 7.8 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3707 PF12499.8 KXZ50638.1 - 3.4e-28 99.0 11.0 3.5e-19 69.8 0.4 2.2 2 0 0 2 2 2 2 Pherophorin MSC PF09402.10 KXZ50639.1 - 0.031 13.7 0.9 0.055 12.9 0.9 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain TRP PF06011.12 KXZ50639.1 - 0.34 9.6 2.5 1.4 7.5 0.8 2.3 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Laminin_EGF PF00053.24 KXZ50639.1 - 1 9.6 4.9 0.32 11.2 1.2 2.1 2 0 0 2 2 2 0 Laminin EGF domain Stress-antifung PF01657.17 KXZ50639.1 - 2 9.1 6.0 7.9 7.2 0.4 3.7 3 0 0 3 3 3 0 Salt stress response/antifungal TRP PF06011.12 KXZ50640.1 - 0.087 11.5 16.9 3 6.5 0.1 2.5 2 1 0 2 2 2 0 Transient receptor potential (TRP) ion channel Ephrin_rec_like PF07699.13 KXZ50640.1 - 0.43 10.4 1.9 28 4.6 0.4 2.7 2 0 0 2 2 2 0 Putative ephrin-receptor like OppC_N PF12911.7 KXZ50640.1 - 7.8 6.6 6.2 49 4.0 2.3 3.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4795 PF16043.5 KXZ50641.1 - 4e-06 26.6 27.2 0.0016 18.1 2.1 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 KXZ50641.1 - 0.2 11.7 13.6 0.13 12.3 0.9 3.9 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KXZ50641.1 - 5.9 7.0 9.4 0.57 10.2 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) CK2S PF15011.6 KXZ50641.1 - 7.9 6.3 13.8 0.82 9.5 0.6 3.3 1 1 2 3 3 3 0 Casein Kinase 2 substrate Glyco_trans_1_4 PF13692.6 KXZ50642.1 - 1.9e-12 47.7 0.0 5.9e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KXZ50642.1 - 8e-12 45.0 0.0 2.3e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycogen_syn PF05693.13 KXZ50642.1 - 0.00017 20.3 0.0 0.00025 19.8 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KXZ50642.1 - 0.0058 16.7 0.0 0.026 14.5 0.0 2.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KXZ50642.1 - 0.18 12.2 0.0 0.65 10.4 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 ACBP PF00887.19 KXZ50643.1 - 2.5e-30 104.5 1.2 2.8e-30 104.4 1.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein UPF0160 PF03690.13 KXZ50644.1 - 1.1e-130 435.9 0.0 1.3e-130 435.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) UCH PF00443.29 KXZ50646.1 - 6.7e-58 196.2 0.0 8.8e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KXZ50646.1 - 7.6e-18 64.9 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KXZ50646.1 - 2e-09 37.5 0.0 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Sde2_N_Ubi PF13019.6 KXZ50646.1 - 0.012 15.4 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain rRNA_proc-arch PF13234.6 KXZ50647.1 - 7.1e-51 173.7 0.0 1.4e-50 172.7 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KXZ50647.1 - 1.5e-44 151.5 0.1 3.1e-44 150.5 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KXZ50647.1 - 2.9e-16 59.7 0.0 5.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ50647.1 - 1.6e-06 28.4 0.0 5.2e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXZ50647.1 - 0.012 15.9 0.0 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain XPA_C PF05181.12 KXZ50650.1 - 3.1e-08 33.5 0.0 5.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 XPA protein C-terminus FAD_binding_7 PF03441.14 KXZ50650.1 - 1.4e-06 27.9 0.1 2.1e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DUF5529 PF17669.1 KXZ50650.1 - 0.12 12.4 4.4 0.38 10.8 4.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5529) Cyclin PF08613.11 KXZ50651.1 - 1.1e-27 97.4 0.0 1.7e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXZ50651.1 - 3.7e-08 33.2 0.0 6.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ICAP-1_inte_bdg PF10480.9 KXZ50651.1 - 0.59 10.1 4.5 1.2 9.1 4.5 1.5 1 0 0 1 1 1 0 Beta-1 integrin binding protein Pkinase_Tyr PF07714.17 KXZ50652.1 - 3.8e-47 160.8 0.0 4.2e-45 154.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50652.1 - 2.8e-36 125.2 0.0 8.1e-23 81.1 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Kdo PF06293.14 KXZ50652.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LELP1 PF15042.6 KXZ50652.1 - 0.045 14.2 3.9 0.15 12.5 3.9 1.8 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 DAD PF02109.16 KXZ50653.1 - 1.1e-30 106.2 0.1 1.2e-30 106.0 0.1 1.1 1 0 0 1 1 1 1 DAD family NiFe_hyd_SSU_C PF14720.6 KXZ50654.1 - 0.38 11.1 3.3 0.87 10.0 0.1 3.0 2 1 1 3 3 3 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Pkinase PF00069.25 KXZ50656.1 - 5.3e-27 94.8 0.0 8.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50656.1 - 3.1e-21 75.8 0.0 5.7e-20 71.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PAN_4 PF14295.6 KXZ50656.1 - 0.014 15.3 6.1 8.3 6.4 0.1 4.3 4 0 0 4 4 4 0 PAN domain PAN_2 PF08276.11 KXZ50656.1 - 0.024 14.8 0.1 9.9 6.4 0.0 2.8 2 0 0 2 2 2 0 PAN-like domain Pkinase PF00069.25 KXZ50658.1 - 1.9e-36 125.8 0.0 3.2e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50658.1 - 1.1e-30 106.8 0.0 1.4e-23 83.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50660.1 - 3.5e-35 121.7 0.0 1.6e-34 119.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50660.1 - 1.1e-31 110.1 0.0 9.9e-26 90.6 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ50660.1 - 0.005 16.8 0.6 0.029 14.3 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ50660.1 - 0.012 14.4 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ50660.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_attach PF05354.11 KXZ50661.1 - 0.86 9.5 0.0 0.86 9.5 0.0 3.2 2 1 1 3 3 3 0 Phage Head-Tail Attachment Pkinase PF00069.25 KXZ50662.1 - 1.3e-23 83.7 0.0 3e-17 62.9 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50662.1 - 3.5e-22 78.9 0.0 2e-16 60.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50664.1 - 1.2e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50664.1 - 2.7e-09 36.7 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PilJ PF13675.6 KXZ50664.1 - 0.042 13.9 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pkinase PF00069.25 KXZ50665.1 - 0.00019 20.9 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50665.1 - 0.0026 17.1 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ50666.1 - 5.9e-18 65.1 0.0 7.1e-09 35.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ50666.1 - 1.1e-16 61.0 0.0 2.3e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DUF4573 PF15140.6 KXZ50666.1 - 1.4 8.7 20.1 0.096 12.5 14.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4573) VPDSG-CTERM PF18205.1 KXZ50666.1 - 2 8.3 6.0 6.8 6.6 6.0 2.0 1 0 0 1 1 1 0 VPDSG-CTERM motif Pkinase PF00069.25 KXZ50668.1 - 3.1e-22 79.2 0.0 1.2e-21 77.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50668.1 - 1.7e-16 60.3 0.0 3.4e-10 39.6 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase MASE1 PF05231.14 KXZ50668.1 - 0.036 13.2 0.2 0.036 13.2 0.2 2.3 2 0 0 2 2 2 0 MASE1 SnoaL_2 PF12680.7 KXZ50668.1 - 0.76 10.4 6.8 0.81 10.4 4.3 2.3 2 0 0 2 2 2 0 SnoaL-like domain Pkinase PF00069.25 KXZ50669.1 - 4.3e-31 108.2 0.0 7.3e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50669.1 - 2.6e-28 99.0 0.0 4.9e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1995 PF09353.10 KXZ50670.1 - 3.4e-43 148.0 0.0 4.3e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) CobT PF06213.12 KXZ50670.1 - 0.022 14.2 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Cecropin PF00272.19 KXZ50671.1 - 4.3 7.1 8.1 2 8.2 1.1 2.7 2 0 0 2 2 2 0 Cecropin family cNMPbd_u2 PF16643.5 KXZ50672.1 - 0.17 12.4 5.8 0.42 11.1 5.8 1.6 1 0 0 1 1 1 0 Unstructured region on cNMP-binding protein YukD PF08817.10 KXZ50672.1 - 0.93 10.2 3.9 13 6.6 0.0 3.7 4 0 0 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD DUF3110 PF11360.8 KXZ50673.1 - 3.4e-05 23.9 0.0 5.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) Methyltransf_25 PF13649.6 KXZ50673.1 - 0.11 13.2 0.1 0.44 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF3707 PF12499.8 KXZ50674.1 - 9.7e-13 48.9 0.1 1.8e-12 48.0 0.1 1.5 1 0 0 1 1 1 1 Pherophorin Metal_resist PF13801.6 KXZ50675.1 - 0.29 11.3 0.0 0.29 11.3 0.0 5.0 6 0 0 6 6 6 0 Heavy-metal resistance zf-C3HC4 PF00097.25 KXZ50677.1 - 4.3e-09 36.1 6.9 7e-09 35.4 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ50677.1 - 1.1e-08 34.8 4.3 1.7e-08 34.2 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ50677.1 - 3e-08 33.9 8.5 4.8e-08 33.2 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXZ50677.1 - 5.2e-08 32.8 7.0 3.3e-07 30.2 7.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ50677.1 - 2e-07 30.7 7.6 3.6e-07 29.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ50677.1 - 1.2e-06 28.3 6.1 2e-06 27.6 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXZ50677.1 - 1.7e-06 28.1 8.9 2.9e-06 27.3 8.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXZ50677.1 - 3.3e-06 26.9 4.4 5.7e-06 26.1 4.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXZ50677.1 - 0.0009 19.2 1.0 0.0015 18.5 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXZ50677.1 - 0.012 15.9 8.4 0.031 14.5 8.5 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 KXZ50677.1 - 0.015 15.2 3.1 0.023 14.7 3.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KXZ50677.1 - 0.091 12.1 2.2 0.45 9.9 2.2 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger zf-Di19 PF05605.12 KXZ50677.1 - 3.8 7.9 6.7 31 5.0 0.1 2.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding YqfQ PF14181.6 KXZ50677.1 - 8.6 6.5 10.8 2 8.6 5.6 2.1 1 1 1 2 2 2 0 YqfQ-like protein Peptidase_S41 PF03572.18 KXZ50678.1 - 2.9e-35 121.3 0.0 4.4e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 KXZ50678.1 - 2.4e-13 49.7 0.1 8.4e-13 48.0 0.1 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ50678.1 - 4.7e-07 30.0 0.0 1.4e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KXZ50678.1 - 1e-06 29.0 0.0 2.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Peptidase_M50 PF02163.22 KXZ50679.1 - 1e-29 103.6 0.6 4.6e-29 101.4 0.6 1.8 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 KXZ50679.1 - 0.18 12.1 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Pkinase_Tyr PF07714.17 KXZ50680.1 - 1.2e-23 83.8 0.0 8e-18 64.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50680.1 - 9.9e-22 77.6 0.0 7.5e-16 58.3 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ50680.1 - 0.6 10.0 0.0 0.6 10.0 0.0 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ50681.1 - 5.3e-35 121.1 0.0 8.6e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50681.1 - 7.6e-33 113.9 0.0 1.6e-32 112.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Rbx_binding PF18113.1 KXZ50681.1 - 0.037 13.8 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain Pkinase_fungal PF17667.1 KXZ50681.1 - 0.3 9.8 0.0 0.57 8.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ50682.1 - 3.2e-22 79.1 0.0 7.9e-09 35.2 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50682.1 - 3.4e-20 72.4 0.0 5.6e-14 52.0 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50683.1 - 5e-28 98.2 0.0 1.3e-26 93.5 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50683.1 - 3.7e-26 92.0 0.0 1.1e-20 74.0 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ50683.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ50684.1 - 1.2e-22 80.5 0.0 9.6e-19 67.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50684.1 - 4.5e-21 75.3 0.0 1.8e-15 56.9 0.0 2.7 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ50684.1 - 0.029 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ50685.1 - 7.1e-14 51.8 0.0 1.9e-10 40.5 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50685.1 - 8.3e-10 38.4 0.0 2e-05 24.0 0.0 2.7 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ50686.1 - 5.3e-42 143.9 0.0 7.5e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50686.1 - 1.3e-38 132.9 0.0 8.7e-38 130.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain GAF PF01590.26 KXZ50686.1 - 0.00014 22.5 0.0 0.00028 21.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain Pkinase_fungal PF17667.1 KXZ50686.1 - 0.0018 17.1 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PAS_9 PF13426.7 KXZ50686.1 - 0.072 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 KXZ50686.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF4680 PF15730.5 KXZ50687.1 - 0.0004 20.7 0.6 0.0004 20.7 0.6 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4680) HABP4_PAI-RBP1 PF04774.15 KXZ50687.1 - 4.9 8.0 11.3 1.1 10.1 8.1 1.6 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Pkinase_Tyr PF07714.17 KXZ50688.1 - 2.6e-11 43.3 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50688.1 - 4e-11 42.8 0.0 5.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ50688.1 - 0.033 13.5 0.0 0.084 12.2 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Guanylate_cyc PF00211.20 KXZ50689.1 - 6.3e-17 61.8 0.0 1.3e-06 28.1 0.0 3.3 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain MHYT PF03707.16 KXZ50689.1 - 0.5 10.6 6.4 1.3 9.2 1.7 3.6 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat UPF0047 PF01894.17 KXZ50690.1 - 5.6e-38 129.6 0.0 6.4e-38 129.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 CxC3 PF18804.1 KXZ50692.1 - 0.0095 15.8 0.1 0.019 14.8 0.1 1.5 1 1 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Acetyltransf_10 PF13673.7 KXZ50693.1 - 1.3e-12 47.8 0.0 1.9e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ50693.1 - 1.4e-12 47.9 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ50693.1 - 1.7e-10 41.2 0.0 3.2e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ50693.1 - 1.5e-06 28.0 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXZ50693.1 - 0.0005 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXZ50693.1 - 0.00064 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXZ50693.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase DUF3947 PF13135.6 KXZ50694.1 - 0.47 10.7 9.3 0.031 14.4 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Trypsin PF00089.26 KXZ50695.1 - 4.8e-40 137.7 0.1 1.3e-39 136.3 0.1 1.8 1 1 0 1 1 1 1 Trypsin CDC27 PF09507.10 KXZ50695.1 - 2.2 7.6 8.1 3.5 6.9 8.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CALCOCO1 PF07888.11 KXZ50697.1 - 0.00069 18.6 24.5 0.00069 18.6 24.5 2.4 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Rootletin PF15035.6 KXZ50697.1 - 0.0014 18.7 4.2 0.0014 18.7 4.2 4.0 2 1 1 3 3 2 1 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 KXZ50697.1 - 0.0022 18.5 7.4 0.0022 18.5 7.4 4.2 3 1 1 4 4 4 1 Apg6 coiled-coil region AAA_13 PF13166.6 KXZ50697.1 - 0.0036 16.0 18.9 0.0044 15.7 10.1 2.1 1 1 1 2 2 2 2 AAA domain NPV_P10 PF05531.12 KXZ50697.1 - 0.037 14.5 1.3 2.9 8.4 0.1 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 KXZ50697.1 - 0.043 14.2 36.4 0.12 12.7 2.5 3.9 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) DUF2459 PF09601.10 KXZ50697.1 - 0.1 12.4 0.2 0.28 11.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) FH2 PF02181.23 KXZ50697.1 - 0.23 10.5 10.0 0.036 13.2 2.7 2.5 2 1 0 2 2 2 0 Formin Homology 2 Domain Mce4_CUP1 PF11887.8 KXZ50697.1 - 0.32 10.4 2.6 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Phage_GPO PF05929.11 KXZ50697.1 - 0.39 10.3 16.9 1 8.9 0.2 2.8 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.6 KXZ50697.1 - 0.5 9.7 33.2 1.2 8.5 22.6 2.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KXZ50697.1 - 0.62 10.5 40.7 0.35 11.3 16.1 3.5 2 2 1 3 3 3 0 Fez1 Spidroin_N PF16763.5 KXZ50697.1 - 0.75 9.8 6.8 0.6 10.1 1.3 2.6 3 0 0 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF1664 PF07889.12 KXZ50697.1 - 1.1 9.3 14.8 5.3 7.1 0.5 4.2 3 2 3 6 6 5 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KXZ50697.1 - 2 8.7 19.0 0.42 10.9 0.7 4.8 3 1 2 5 5 5 0 Uncharacterized conserved protein DUF948 PF06103.11 KXZ50697.1 - 3.4 8.0 7.2 11 6.4 0.6 4.1 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) IFP_35_N PF07334.13 KXZ50697.1 - 3.5 7.8 7.9 0.27 11.3 0.8 2.9 3 1 0 3 3 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Fib_alpha PF08702.10 KXZ50697.1 - 4.9 7.3 12.7 16 5.7 0.2 3.7 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF1216 PF06746.11 KXZ50697.1 - 5.3 7.0 7.2 0.52 10.3 0.4 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1216) DUF812 PF05667.11 KXZ50697.1 - 7 5.4 25.2 0.07 12.0 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF812) p25-alpha PF05517.12 KXZ50700.1 - 1.7e-10 41.3 0.0 1.8e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 p25-alpha TPR_2 PF07719.17 KXZ50701.1 - 4.7e-33 110.6 24.7 0.00013 21.8 1.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ50701.1 - 1.1e-32 110.5 18.2 9e-06 25.3 0.7 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ50701.1 - 3.2e-29 98.6 12.7 0.00015 21.7 0.2 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ50701.1 - 1.7e-16 59.6 12.0 5.7e-06 25.9 0.8 6.5 4 2 3 7 7 6 3 TPR repeat TPR_19 PF14559.6 KXZ50701.1 - 2e-16 60.3 28.2 3.2e-08 34.0 2.8 7.6 4 4 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ50701.1 - 5.9e-16 58.8 41.1 8.6e-11 42.3 0.3 8.7 8 1 2 10 10 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ50701.1 - 1.1e-12 47.6 21.7 0.023 15.5 0.3 8.0 3 1 5 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ50701.1 - 4.5e-12 45.5 15.2 0.0024 18.1 0.1 7.2 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ50701.1 - 6.5e-12 45.6 27.2 0.03 14.6 1.2 7.6 5 1 3 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ50701.1 - 1.5e-11 44.4 19.7 9.7e-05 22.5 2.1 4.8 5 0 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXZ50701.1 - 1.8e-11 44.0 12.2 3.9e-05 23.7 0.0 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ50701.1 - 2.8e-08 33.2 11.0 2.3 8.5 0.2 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ50701.1 - 3.7e-06 27.2 25.2 4.4 8.1 0.1 9.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ50701.1 - 0.0088 15.3 4.6 0.6 9.3 0.8 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ50701.1 - 0.031 14.6 0.7 0.031 14.6 0.7 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KXZ50701.1 - 0.04 13.9 1.2 25 4.9 0.0 3.2 2 1 0 2 2 2 0 Putative TPR-like repeat SHNi-TPR PF10516.9 KXZ50701.1 - 0.055 12.9 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR Velvet PF11754.8 KXZ50701.1 - 0.081 12.9 4.6 0.14 12.1 4.6 1.3 1 0 0 1 1 1 0 Velvet factor Fis1_TPR_C PF14853.6 KXZ50701.1 - 0.12 12.5 7.1 2.1 8.5 0.2 4.5 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Endostatin PF06482.11 KXZ50701.1 - 0.2 11.1 5.3 0.33 10.4 5.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Neur_chan_memb PF02932.16 KXZ50701.1 - 0.3 11.1 1.3 0.48 10.4 1.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 KXZ50701.1 - 0.34 9.8 14.7 0.5 9.3 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 KXZ50701.1 - 0.42 9.5 4.0 0.58 9.1 4.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SelP_N PF04592.14 KXZ50701.1 - 1.7 8.0 21.3 2.8 7.3 21.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Suf PF05843.14 KXZ50701.1 - 2.5 8.0 6.6 4 7.3 6.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 KXZ50701.1 - 4.2 6.0 7.9 6 5.5 7.9 1.1 1 0 0 1 1 1 0 Presenilin DUF2225 PF09986.9 KXZ50701.1 - 7.9 6.1 6.3 17 5.1 2.2 3.0 3 1 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2225) NARP1 PF12569.8 KXZ50701.1 - 9 5.1 13.1 4.3 6.1 0.1 3.1 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 Sugar_tr PF00083.24 KXZ50702.1 - 2e-35 122.5 8.8 2.3e-35 122.3 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXZ50702.1 - 1.4e-14 53.8 19.5 1.7e-14 53.6 19.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KXZ50702.1 - 0.046 14.3 2.0 0.046 14.3 2.0 2.4 1 1 1 2 2 2 0 Phage holin family 2 MFS_1_like PF12832.7 KXZ50702.1 - 0.074 11.9 1.0 0.11 11.3 1.0 1.3 1 0 0 1 1 1 0 MFS_1 like family SEC-C PF02810.15 KXZ50703.1 - 1.2e-05 25.1 5.8 2.1e-05 24.3 5.8 1.4 1 0 0 1 1 1 1 SEC-C motif UPF0225 PF17775.1 KXZ50703.1 - 4.4e-05 24.2 0.0 0.00012 22.8 0.0 1.8 2 1 0 2 2 2 1 UPF0225 domain PfkB PF00294.24 KXZ50703.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.4 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Sugar_tr PF00083.24 KXZ50704.1 - 3.8e-36 124.9 4.1 5.3e-36 124.4 4.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Uso1_p115_C PF04871.13 KXZ50704.1 - 6.7e-05 23.3 8.3 6.7e-05 23.3 8.3 2.1 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 KXZ50704.1 - 0.67 10.2 4.5 3.7 7.8 4.5 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 KXZ50704.1 - 0.79 9.7 3.1 4.9 7.2 2.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 KXZ50705.1 - 2.8e-05 24.5 9.2 2.8e-05 24.5 9.2 2.2 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Macoilin PF09726.9 KXZ50705.1 - 0.095 11.2 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Macoilin family CENP-F_leu_zip PF10473.9 KXZ50705.1 - 0.13 12.2 4.5 0.8 9.7 3.1 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 KXZ50705.1 - 0.26 11.5 1.0 0.52 10.6 1.0 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.8 KXZ50705.1 - 1.6 9.0 10.4 0.41 10.9 5.7 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KXZ50705.1 - 2.7 8.5 9.7 10 6.7 9.5 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Chloroa_b-bind PF00504.21 KXZ50706.1 - 4.1e-13 50.2 0.9 1.2e-05 25.9 0.1 2.3 2 0 0 2 2 2 2 Chlorophyll A-B binding protein TRAP_alpha PF03896.16 KXZ50707.1 - 1.5e-22 80.1 0.4 1.8e-22 79.9 0.4 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit dsrm PF00035.26 KXZ50708.1 - 8.4e-08 32.8 7.6 1.1e-05 26.0 0.1 2.7 2 1 0 2 2 2 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 KXZ50708.1 - 0.00084 19.4 2.2 0.46 10.7 0.0 2.3 2 0 0 2 2 2 2 Dicer dimerisation domain SelB-wing_2 PF09106.11 KXZ50708.1 - 0.0028 17.8 2.3 3.5 7.9 0.4 3.7 4 1 0 4 4 4 2 Elongation factor SelB, winged helix Helicase_C PF00271.31 KXZ50710.1 - 5.5e-09 36.4 0.0 8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3372 PF11852.8 KXZ50711.1 - 7.9e-47 158.8 0.0 1.2e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3372) zf-MYND PF01753.18 KXZ50712.1 - 1.8e-07 31.1 10.1 1.8e-07 31.1 10.1 2.0 2 0 0 2 2 2 1 MYND finger POR_N PF01855.19 KXZ50713.1 - 4.3e-80 268.8 3.0 7.4e-80 268.0 3.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KXZ50713.1 - 7.6e-29 101.0 0.4 1.3e-28 100.2 0.4 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KXZ50713.1 - 2.8e-13 50.0 0.0 8.4e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II EKR PF10371.9 KXZ50713.1 - 1.7e-12 46.9 0.0 6.6e-12 45.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function TPP_enzyme_C PF02775.21 KXZ50713.1 - 1.2e-08 34.8 0.0 3.6e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.6 KXZ50713.1 - 7.3e-08 33.2 10.1 1.2e-06 29.4 10.2 2.5 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KXZ50713.1 - 7.9e-08 32.3 6.9 0.002 18.2 0.5 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXZ50713.1 - 8.4e-08 32.7 5.9 2.4e-07 31.2 5.9 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KXZ50713.1 - 1.3e-07 31.2 19.9 0.0001 21.9 2.9 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 KXZ50713.1 - 8e-07 29.1 9.5 0.0016 18.6 1.7 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXZ50713.1 - 9.4e-06 25.5 21.1 6.8e-05 22.8 4.3 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KXZ50713.1 - 2.5e-05 24.7 4.1 7.5e-05 23.1 4.1 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXZ50713.1 - 0.00015 21.8 11.4 0.00024 21.2 9.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Transketolase_C PF02780.20 KXZ50713.1 - 0.00055 19.8 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Fer4_2 PF12797.7 KXZ50713.1 - 0.0025 17.8 22.1 0.0074 16.3 3.6 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXZ50713.1 - 0.011 16.2 13.4 0.087 13.4 12.0 2.7 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KXZ50713.1 - 0.07 13.7 9.6 0.18 12.4 2.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KXZ50713.1 - 7 6.9 9.7 11 6.3 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AlaDh_PNT_N PF05222.15 KXZ50714.1 - 3.7e-42 143.9 0.4 6.3e-42 143.1 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KXZ50714.1 - 9.8e-41 139.4 3.3 9.8e-41 139.4 3.3 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KXZ50714.1 - 0.0056 15.9 0.4 0.0056 15.9 0.4 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXZ50714.1 - 0.012 15.0 1.2 0.28 10.5 0.3 2.7 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXZ50714.1 - 0.015 15.8 1.6 0.031 14.8 1.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Citrate_bind PF16114.5 KXZ50714.1 - 0.019 14.5 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding DHDPS PF00701.22 KXZ50714.1 - 0.089 11.5 0.3 0.82 8.3 0.1 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family XdhC_C PF13478.6 KXZ50714.1 - 0.097 13.2 0.5 0.78 10.3 0.0 2.2 2 1 0 2 2 2 0 XdhC Rossmann domain HI0933_like PF03486.14 KXZ50714.1 - 0.12 11.1 2.9 0.18 10.5 2.9 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KXZ50714.1 - 0.18 10.8 2.3 0.27 10.3 2.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXZ50714.1 - 0.21 11.8 2.5 0.73 10.1 1.8 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PAP2 PF01569.21 KXZ50715.1 - 8.8e-28 96.8 1.4 1.8e-27 95.8 0.6 1.7 2 0 0 2 2 2 1 PAP2 superfamily GtrA PF04138.14 KXZ50715.1 - 0.96 9.7 3.9 0.79 10.0 0.7 2.0 2 0 0 2 2 2 0 GtrA-like protein Pkinase PF00069.25 KXZ50716.1 - 4.4e-46 157.4 0.0 5.7e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50716.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50716.1 - 0.00037 19.9 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ50716.1 - 0.035 12.9 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FKBP_C PF00254.28 KXZ50717.1 - 3.2e-19 69.0 0.0 4.5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PsbQ PF05757.11 KXZ50717.1 - 0.00047 20.0 3.3 0.00067 19.5 3.3 1.2 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) TAT_signal PF10518.9 KXZ50717.1 - 0.042 13.7 1.4 0.12 12.3 1.4 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 KXZ50717.1 - 0.12 11.8 2.3 0.29 10.5 2.3 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Leu_leader PF08054.11 KXZ50717.1 - 6.7 6.4 6.1 5.8 6.6 2.5 2.3 2 0 0 2 2 2 0 Leucine operon leader peptide CCDC106 PF15794.5 KXZ50718.1 - 0.00095 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 HAUS5 PF14817.6 KXZ50718.1 - 0.0074 15.1 0.0 0.0095 14.8 0.0 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Mod_r PF07200.13 KXZ50718.1 - 0.049 13.7 4.0 0.07 13.2 4.0 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.9 KXZ50718.1 - 0.08 12.0 3.1 0.11 11.6 3.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KXZ50718.1 - 0.089 13.0 6.2 0.14 12.3 6.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 KXZ50718.1 - 0.12 12.0 1.3 0.16 11.6 1.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Sec2p PF06428.11 KXZ50718.1 - 0.19 11.7 2.9 0.28 11.2 2.9 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p YabA PF06156.13 KXZ50718.1 - 0.24 12.1 0.7 0.38 11.4 0.7 1.3 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KXZ50718.1 - 0.32 11.5 6.1 0.53 10.8 6.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 KXZ50718.1 - 0.33 11.5 4.2 0.6 10.6 4.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 KXZ50718.1 - 0.34 11.0 9.5 0.21 11.7 6.0 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 KXZ50718.1 - 0.74 9.9 2.4 1.1 9.4 2.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NEMO PF11577.8 KXZ50718.1 - 0.76 9.8 4.0 1.2 9.2 4.0 1.3 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO TSC22 PF01166.18 KXZ50718.1 - 2 8.8 3.3 14 6.1 0.7 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family LRR_9 PF14580.6 KXZ50719.1 - 5.6e-09 35.7 0.1 1.2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KXZ50719.1 - 6.6e-06 26.4 5.2 0.0019 18.6 3.3 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ50719.1 - 0.049 13.7 0.9 18 5.7 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 KXZ50719.1 - 0.089 12.6 4.7 0.061 13.1 1.5 2.1 2 1 0 2 2 2 0 Leucine rich repeat Pex14_N PF04695.13 KXZ50721.1 - 0.028 15.1 3.1 0.085 13.5 0.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_11 PF13086.6 KXZ50722.1 - 4.1e-19 69.4 0.0 5.5e-11 42.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KXZ50722.1 - 1.2e-13 51.2 0.0 4.5e-13 49.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ50722.1 - 4.7e-10 40.0 0.1 1.3e-09 38.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ50722.1 - 0.0013 19.2 0.0 0.0035 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 KXZ50722.1 - 0.061 12.5 0.2 0.12 11.6 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KXZ50722.1 - 0.063 13.7 0.2 0.2 12.1 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KXZ50722.1 - 0.067 12.9 0.8 0.42 10.4 0.8 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 KXZ50722.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_12 PF13087.6 KXZ50722.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXZ50722.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KXZ50723.1 - 2.4e-18 66.9 1.4 1.2e-10 41.6 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KXZ50723.1 - 8.6e-14 51.7 0.0 2.5e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ50723.1 - 1.6e-10 41.5 0.0 3.9e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ50723.1 - 0.0013 19.1 0.0 0.005 17.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain DNA_pol_A_exo1 PF01612.20 KXZ50723.1 - 0.016 15.0 0.0 0.053 13.2 0.0 1.7 2 0 0 2 2 2 0 3'-5' exonuclease Pex14_N PF04695.13 KXZ50723.1 - 0.035 14.8 2.7 0.064 13.9 2.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DEAD PF00270.29 KXZ50723.1 - 0.04 13.7 0.4 0.21 11.4 0.4 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 KXZ50723.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXZ50723.1 - 0.055 12.7 0.1 0.13 11.5 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KXZ50723.1 - 0.056 13.9 0.3 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KXZ50723.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Protein_K PF12283.8 KXZ50724.1 - 0.18 12.0 0.3 0.37 11.0 0.3 1.4 1 0 0 1 1 1 0 Bacteriophage protein K Mto2_bdg PF12808.7 KXZ50724.1 - 6.3 7.2 7.6 2.2 8.6 0.6 2.4 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SGP PF17228.2 KXZ50726.1 - 0.0049 17.7 12.2 0.012 16.5 12.2 1.6 1 0 0 1 1 1 1 Sulphur globule protein HA2 PF04408.23 KXZ50727.1 - 3.8e-16 59.3 1.4 2.7e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXZ50727.1 - 2.2e-14 53.5 0.0 3.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXZ50727.1 - 6.2e-07 29.7 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Methyltransf_20 PF12147.8 KXZ50727.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase PAS_10 PF13596.6 KXZ50728.1 - 0.00029 21.4 0.1 1.4 9.5 0.0 2.3 2 0 0 2 2 2 2 PAS domain PALB2_WD40 PF16756.5 KXZ50728.1 - 0.0076 15.2 0.3 0.011 14.6 0.3 1.2 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain OHA PF14418.6 KXZ50728.1 - 0.056 13.3 1.0 2.2 8.2 0.1 2.5 2 0 0 2 2 2 0 OST-HTH Associated domain TPD52 PF04201.15 KXZ50728.1 - 0.13 11.9 0.3 0.21 11.2 0.3 1.3 1 0 0 1 1 1 0 Tumour protein D52 family PALP PF00291.25 KXZ50728.1 - 0.35 10.2 4.0 5.5 6.3 0.2 2.2 1 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme OB_NTP_bind PF07717.16 KXZ50729.1 - 7.7e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold MULE PF10551.9 KXZ50729.1 - 1.5e-05 25.4 0.0 2.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Ribosomal_S10 PF00338.22 KXZ50730.1 - 2e-10 40.8 0.0 1e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e RCC1 PF00415.18 KXZ50732.1 - 6.5e-62 206.0 20.8 4.3e-16 59.3 0.5 6.2 5 1 1 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ50732.1 - 8.7e-24 82.8 25.1 4.6e-08 32.7 2.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 KXZ50732.1 - 0.083 13.1 5.8 5.8 7.2 0.1 3.2 3 1 0 3 3 3 0 Putative heavy-metal chelation DUF346 PF03984.13 KXZ50732.1 - 0.25 11.1 6.0 11 5.8 0.1 3.9 4 0 0 4 4 4 0 Repeat of unknown function (DUF346) Methyltranf_PUA PF13636.6 KXZ50732.1 - 0.28 11.2 0.9 2.2 8.3 0.2 2.7 3 0 0 3 3 3 0 RNA-binding PUA-like domain of methyltransferase RsmF CENP-T_C PF15511.6 KXZ50733.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50733.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ50733.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ50733.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50733.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ50733.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ50733.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ50734.1 - 8.4e-22 77.9 4.3 1.2e-21 77.4 4.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50734.1 - 2.3e-05 24.6 0.1 8.3e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ50734.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ50734.1 - 0.031 13.9 0.8 1.2 8.8 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ50734.1 - 0.037 14.1 6.5 0.087 12.9 6.5 1.6 1 1 0 1 1 1 0 YscO-like protein DUF3391 PF11871.8 KXZ50734.1 - 2.6 8.6 8.9 7.4 7.1 8.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone_H2A_C PF16211.5 KXZ50735.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ50735.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50735.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ank_2 PF12796.7 KXZ50736.1 - 0.0042 17.6 0.0 0.0099 16.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ50736.1 - 0.0073 16.6 0.4 0.018 15.4 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50736.1 - 0.033 14.7 0.3 0.28 11.9 0.2 2.6 3 0 0 3 3 3 0 Ankyrin repeat VWA PF00092.28 KXZ50737.1 - 5.7e-08 33.2 0.0 8.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXZ50737.1 - 0.00016 22.3 0.1 0.00047 20.8 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain zf_CCCH_4 PF18345.1 KXZ50737.1 - 1.4 9.1 3.8 3.2 7.9 3.8 1.6 1 0 0 1 1 1 0 Zinc finger domain ArsA_ATPase PF02374.15 KXZ50739.1 - 6.9e-126 419.5 0.0 1.1e-63 215.3 0.0 2.4 2 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 KXZ50739.1 - 2.6e-21 76.0 0.0 2.7e-10 40.4 0.0 2.5 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXZ50739.1 - 3.6e-16 59.6 0.7 1.2e-06 28.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain ParA PF10609.9 KXZ50739.1 - 2.2e-13 50.3 9.1 1.1e-05 25.0 0.3 4.8 5 0 0 5 5 5 3 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KXZ50739.1 - 8e-08 32.1 0.3 0.007 16.0 0.3 2.9 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KXZ50739.1 - 1e-07 31.7 0.3 0.008 15.7 0.1 2.5 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KXZ50739.1 - 1.7e-06 27.7 0.1 0.0061 16.0 0.0 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 KXZ50739.1 - 5.5e-06 26.9 0.6 0.016 15.6 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 KXZ50739.1 - 6.2e-05 22.8 0.1 0.053 13.2 0.0 3.3 2 2 0 2 2 2 1 AAA domain ATPase PF06745.13 KXZ50739.1 - 7.1e-05 22.3 0.0 0.04 13.3 0.0 2.6 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KXZ50739.1 - 0.00011 21.9 6.2 0.11 12.1 0.2 3.3 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KXZ50739.1 - 0.00036 20.3 0.2 0.041 13.6 0.1 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 KXZ50739.1 - 0.00088 19.2 0.5 0.19 11.6 0.1 2.5 2 0 0 2 2 2 1 NACHT domain PhoH PF02562.16 KXZ50739.1 - 0.00092 18.7 0.0 0.077 12.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Med9 PF07544.13 KXZ50739.1 - 0.0017 18.4 1.0 0.025 14.6 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 MeaB PF03308.16 KXZ50739.1 - 0.0034 16.4 0.5 0.12 11.3 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KXZ50739.1 - 0.0041 16.4 0.2 1.8 7.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 KXZ50739.1 - 0.0042 17.0 1.2 0.49 10.3 0.1 3.1 3 0 0 3 3 3 1 RsgA GTPase CLP1_P PF16575.5 KXZ50739.1 - 0.0055 16.5 0.7 1.5 8.6 0.1 3.0 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 KXZ50739.1 - 0.0098 15.7 1.7 2 8.1 0.2 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KXZ50739.1 - 0.0099 15.1 0.1 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 KXZ50739.1 - 0.013 16.1 0.7 2 9.0 0.2 3.4 3 1 0 3 3 2 0 AAA domain DUF3763 PF12592.8 KXZ50739.1 - 0.014 15.5 2.1 3.5 7.8 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3763) DnaB_C PF03796.15 KXZ50739.1 - 0.016 14.5 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 KXZ50739.1 - 0.019 15.4 0.0 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KXZ50739.1 - 0.019 14.5 0.1 3 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KXZ50739.1 - 0.028 14.4 0.0 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXZ50739.1 - 0.042 13.6 3.6 1.8 8.2 0.3 3.4 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 KXZ50739.1 - 0.052 12.7 0.0 6.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KXZ50739.1 - 0.1 12.8 1.4 3.2 7.9 0.4 3.2 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXZ50739.1 - 0.12 11.4 0.6 5.1 6.1 0.0 3.3 3 1 0 3 3 3 0 Type II/IV secretion system protein TsaE PF02367.17 KXZ50739.1 - 0.16 11.9 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 KXZ50739.1 - 0.17 11.0 0.1 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.29 KXZ50739.1 - 0.25 11.8 1.2 16 5.9 0.1 3.1 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 KXZ50739.1 - 0.6 9.8 1.7 14 5.3 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family LpxK PF02606.14 KXZ50739.1 - 3.3 6.7 7.7 2.6 7.1 0.1 3.0 4 0 0 4 4 4 0 Tetraacyldisaccharide-1-P 4'-kinase Rubredoxin PF00301.20 KXZ50740.1 - 5.5e-05 23.1 5.9 0.011 15.8 5.9 2.4 1 1 0 1 1 1 1 Rubredoxin Zn-ribbon_8 PF09723.10 KXZ50740.1 - 0.0013 18.8 1.0 0.0021 18.1 1.0 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-Mss51 PF13824.6 KXZ50740.1 - 0.012 15.7 2.7 1.1 9.4 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_10 PF10058.9 KXZ50740.1 - 0.02 14.6 1.5 1 9.2 0.1 2.3 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 KXZ50740.1 - 0.039 14.0 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 KXZ50740.1 - 0.04 13.4 0.5 9 5.9 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 KXZ50740.1 - 0.12 12.3 3.4 0.64 10.0 3.4 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DZR PF12773.7 KXZ50740.1 - 0.14 12.2 0.5 0.47 10.5 0.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_2 PF13639.6 KXZ50741.1 - 8.2e-10 38.9 7.2 1.3e-09 38.2 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXZ50741.1 - 2.1e-07 30.8 5.2 3.5e-07 30.2 5.2 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXZ50741.1 - 6.3e-07 29.2 6.4 9.3e-07 28.6 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXZ50741.1 - 9.2e-07 28.5 2.6 1.7e-06 27.7 2.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXZ50741.1 - 1.6e-06 27.8 7.6 2.6e-06 27.2 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ50741.1 - 2e-05 24.8 4.8 4.3e-05 23.7 4.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXZ50741.1 - 9.1e-05 22.4 0.9 0.00016 21.7 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXZ50741.1 - 0.00018 21.3 4.1 0.00029 20.6 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ50741.1 - 0.00024 21.0 6.1 0.00037 20.4 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXZ50741.1 - 0.002 17.7 4.6 0.0038 16.8 4.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXZ50741.1 - 0.0031 17.6 7.5 0.0052 16.9 7.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXZ50741.1 - 0.076 12.8 5.1 0.12 12.2 5.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXZ50741.1 - 0.15 12.3 6.2 0.42 10.8 6.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KXZ50741.1 - 1 9.3 7.2 1.8 8.5 7.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KXZ50741.1 - 2.1 8.3 5.8 3.5 7.6 5.8 1.4 1 0 0 1 1 1 0 PHD-finger LIM PF00412.22 KXZ50741.1 - 2.7 8.3 4.1 15 5.9 0.3 2.3 2 0 0 2 2 2 0 LIM domain RINGv PF12906.7 KXZ50741.1 - 5 7.3 6.2 9.5 6.4 6.2 1.5 1 0 0 1 1 1 0 RING-variant domain Amino_oxidase PF01593.24 KXZ50742.1 - 1.4e-56 192.7 0.1 2e-56 192.2 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ50742.1 - 1.7e-10 41.0 0.1 4.4e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ50742.1 - 7.5e-07 28.6 0.4 1.2e-06 27.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXZ50742.1 - 2.4e-05 24.1 1.6 0.00021 21.0 0.9 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXZ50742.1 - 4e-05 23.1 0.5 6.3e-05 22.5 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ50742.1 - 0.00011 21.5 0.2 0.00018 20.8 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ50742.1 - 0.005 16.1 0.1 0.0098 15.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXZ50742.1 - 0.021 14.1 0.2 0.031 13.5 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ50742.1 - 0.054 12.2 0.2 0.077 11.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KXZ50742.1 - 0.12 11.4 0.2 0.19 10.7 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXZ50742.1 - 0.16 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXZ50742.1 - 0.19 10.8 0.5 0.28 10.2 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SRP54 PF00448.22 KXZ50743.1 - 5.2e-66 222.0 0.0 7.2e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KXZ50743.1 - 5.5e-10 39.3 0.1 1.3e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KXZ50743.1 - 1.3e-05 25.1 0.3 3e-05 23.8 0.3 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXZ50743.1 - 1.5e-05 24.5 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KXZ50743.1 - 2.8e-05 24.6 1.6 0.0001 22.7 0.2 2.4 1 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 KXZ50743.1 - 9.3e-05 22.1 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KXZ50743.1 - 0.00014 21.2 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KXZ50743.1 - 0.00039 20.7 0.0 0.0021 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KXZ50743.1 - 0.00067 19.7 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 KXZ50743.1 - 0.0011 19.0 0.6 0.0077 16.2 0.6 2.1 1 1 0 1 1 1 1 NACHT domain AAA_17 PF13207.6 KXZ50743.1 - 0.0023 18.4 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KXZ50743.1 - 0.0029 16.6 0.2 0.0059 15.6 0.2 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KXZ50743.1 - 0.0068 16.3 0.1 0.021 14.8 0.0 1.6 1 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KXZ50743.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.6 KXZ50743.1 - 0.011 15.9 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXZ50743.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 KXZ50743.1 - 0.013 13.0 0.2 0.019 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.23 KXZ50743.1 - 0.024 14.7 0.0 0.13 12.4 0.0 2.2 1 1 1 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 KXZ50743.1 - 0.026 14.2 0.1 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_33 PF13671.6 KXZ50743.1 - 0.026 14.7 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ50743.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 KXZ50743.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.15 KXZ50743.1 - 0.053 13.5 0.0 0.092 12.7 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KXZ50743.1 - 0.058 13.4 0.0 0.29 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ50743.1 - 0.06 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KXZ50743.1 - 0.12 12.9 0.3 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 KXZ50743.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 KXZ50743.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXZ50743.1 - 0.15 11.8 0.1 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MraZ PF02381.18 KXZ50743.1 - 0.18 11.8 0.1 15 5.7 0.0 2.4 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like Ferric_reduct PF01794.19 KXZ50746.1 - 6.1e-12 45.7 5.0 6.1e-12 45.7 5.0 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXZ50746.1 - 5.5e-05 23.3 0.0 0.16 12.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXZ50746.1 - 0.00023 21.2 0.0 0.00036 20.6 0.0 1.2 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXZ50746.1 - 0.16 12.6 0.0 0.41 11.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain TP_methylase PF00590.20 KXZ50748.1 - 5.3e-39 134.4 3.6 1.3e-38 133.1 3.6 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Exostosin PF03016.15 KXZ50749.1 - 4.3e-48 164.0 0.7 9.3e-48 163.0 0.7 1.5 1 1 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ50749.1 - 0.049 14.0 24.7 0.18 12.2 17.7 2.8 2 0 0 2 2 2 0 EGF-like domain TspO_MBR PF03073.15 KXZ50750.1 - 2.1e-44 150.9 13.0 3e-44 150.3 13.0 1.2 1 0 0 1 1 1 1 TspO/MBR family Exotox-A_target PF09102.10 KXZ50750.1 - 0.023 14.7 3.2 0.042 13.8 3.2 1.4 1 0 0 1 1 1 0 Exotoxin A, targeting NYN PF01936.18 KXZ50751.1 - 0.00033 21.2 0.0 0.0016 18.9 0.0 1.9 1 1 0 1 1 1 1 NYN domain LSDAT_prok PF18171.1 KXZ50751.1 - 0.00062 19.1 0.0 0.00079 18.7 0.0 1.1 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Fibrillarin_2 PF10113.9 KXZ50751.1 - 0.068 11.8 0.0 0.089 11.4 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Trypan_PARP PF05887.11 KXZ50752.1 - 0.0009 19.2 39.6 0.0009 19.2 39.6 3.5 4 1 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 KXZ50752.1 - 0.025 13.1 9.9 0.038 12.5 9.9 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Cwf_Cwc_15 PF04889.12 KXZ50758.1 - 1.1e-76 257.9 11.5 1.3e-76 257.6 11.5 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 KXZ50758.1 - 0.23 11.3 17.4 0.056 13.3 14.4 1.4 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Nop14 PF04147.12 KXZ50758.1 - 0.67 8.1 16.6 0.75 7.9 16.6 1.0 1 0 0 1 1 1 0 Nop14-like family Exostosin PF03016.15 KXZ50759.1 - 3.6e-45 154.5 0.0 5.1e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ50759.1 - 0.013 15.9 13.4 0.013 15.9 13.4 2.8 2 0 0 2 2 2 0 EGF-like domain PKD PF00801.20 KXZ50761.1 - 0.00041 20.1 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 PKD domain DUF1180 PF06679.12 KXZ50761.1 - 2 8.8 4.2 3 8.2 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ribosomal_60s PF00428.19 KXZ50761.1 - 2.7 8.6 6.0 5.5 7.7 6.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cu_bind_like PF02298.17 KXZ50762.1 - 0.00019 21.4 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 KXZ50762.1 - 0.00042 20.7 0.2 0.0013 19.1 0.2 1.8 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family SoxE PF06525.11 KXZ50762.1 - 0.0064 16.0 0.3 1.2 8.6 0.1 2.6 1 1 1 2 2 2 2 Sulfocyanin (SoxE) domain Peptidase_C48 PF02902.19 KXZ50764.1 - 8.9e-18 64.9 0.1 1.2e-17 64.4 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Rieske PF00355.26 KXZ50765.1 - 3e-20 71.9 0.0 5.5e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXZ50765.1 - 2.1e-05 24.4 0.0 9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain zf-CCCH PF00642.24 KXZ50766.1 - 4.9e-10 39.1 14.5 0.0015 18.4 1.0 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXZ50766.1 - 4.2e-08 33.0 20.7 1.4e-05 25.0 1.3 3.6 3 1 0 3 3 3 2 Zinc finger domain Torus PF16131.5 KXZ50766.1 - 1.7e-06 28.7 10.4 6.9e-05 23.5 1.0 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KXZ50766.1 - 0.0032 17.7 10.5 0.0097 16.1 5.3 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KXZ50766.1 - 0.0034 17.2 0.3 0.0034 17.2 0.3 3.3 4 0 0 4 4 4 2 CCCH-type zinc finger zf-C3H1 PF10650.9 KXZ50766.1 - 0.079 12.7 4.3 3.4 7.5 0.7 3.2 3 0 0 3 3 3 0 Putative zinc-finger domain YgbA_NO PF11756.8 KXZ50766.1 - 0.36 11.2 4.1 0.59 10.5 4.1 1.4 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter zf-CCCH_2 PF14608.6 KXZ50766.1 - 1.3 9.6 15.7 7.1 7.3 0.4 3.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger TFIIF_beta PF02270.15 KXZ50769.1 - 4.3e-20 71.6 0.2 8.3e-20 70.7 0.2 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KXZ50769.1 - 1.6e-07 32.1 0.0 3.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TraC PF07820.12 KXZ50769.1 - 0.78 10.1 3.6 0.89 9.9 0.1 2.5 2 1 1 3 3 3 0 TraC-like protein Hint PF01079.20 KXZ50770.1 - 1.1e-21 77.3 0.0 1.9e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Hint module EF-hand_5 PF13202.6 KXZ50770.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ50770.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KXZ50771.1 - 0.00065 19.1 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ50771.1 - 0.0083 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 EF hand Phage_Mu_Gp45 PF06890.12 KXZ50771.1 - 0.0098 15.6 0.2 1.4 8.7 0.1 3.2 3 0 0 3 3 3 1 Bacteriophage Mu Gp45 protein HTH_13 PF11972.8 KXZ50771.1 - 0.011 15.7 0.0 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain EF-hand_6 PF13405.6 KXZ50771.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Hint PF01079.20 KXZ50772.1 - 3.7e-23 82.2 0.0 5.8e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Hint module SLY PF12485.8 KXZ50772.1 - 0.18 12.5 0.0 0.26 12.0 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Pkinase_Tyr PF07714.17 KXZ50773.1 - 8.2e-34 117.0 0.0 3.6e-25 88.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50773.1 - 4.1e-23 82.1 0.0 7.4e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ50773.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ50773.1 - 0.056 13.4 0.6 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family T2SSK PF03934.13 KXZ50775.1 - 0.0034 16.8 0.1 0.0046 16.4 0.1 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K VBS PF08913.10 KXZ50775.1 - 0.03 14.8 0.1 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Vinculin Binding Site Spc7 PF08317.11 KXZ50776.1 - 0.00014 20.8 24.2 0.00014 20.8 24.2 7.2 1 1 5 7 7 7 4 Spc7 kinetochore protein Nop10p PF04135.12 KXZ50777.1 - 4.1e-23 81.2 0.8 4.8e-23 80.9 0.8 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Nnf1 PF03980.14 KXZ50778.1 - 6.4e-05 23.3 0.2 0.00011 22.5 0.2 1.5 1 1 0 1 1 1 1 Nnf1 Herpes_UL14 PF03580.14 KXZ50778.1 - 0.0029 17.8 0.7 0.0044 17.3 0.5 1.4 1 1 0 1 1 1 1 Herpesvirus UL14-like protein DUF2285 PF10074.9 KXZ50778.1 - 0.034 14.8 1.6 0.034 14.8 1.6 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) DUF4349 PF14257.6 KXZ50778.1 - 0.077 12.4 2.4 0.13 11.7 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AAA PF00004.29 KXZ50779.1 - 2.8e-41 141.1 0.0 6.1e-41 139.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ50779.1 - 5.6e-10 38.9 0.4 1e-09 38.0 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KXZ50779.1 - 3.3e-09 36.6 0.0 7.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KXZ50779.1 - 5e-05 23.6 0.2 0.023 14.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KXZ50779.1 - 5.4e-05 23.4 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KXZ50779.1 - 7e-05 22.1 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXZ50779.1 - 0.0002 21.4 0.2 0.0014 18.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ50779.1 - 0.00037 20.9 0.2 0.0026 18.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXZ50779.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXZ50779.1 - 0.0085 16.6 0.0 0.035 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KXZ50779.1 - 0.01 15.2 0.3 0.73 9.1 0.1 2.5 2 1 0 3 3 3 1 KaiC AAA_3 PF07726.11 KXZ50779.1 - 0.016 15.0 0.1 0.097 12.5 0.0 2.2 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KXZ50779.1 - 0.016 14.4 0.1 0.037 13.2 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KXZ50779.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 KXZ50779.1 - 0.038 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXZ50779.1 - 0.045 14.2 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KXZ50779.1 - 0.06 13.3 0.1 0.35 10.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.22 KXZ50779.1 - 0.07 12.3 0.1 1.1 8.4 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 KXZ50779.1 - 0.092 12.5 0.2 0.25 11.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KXZ50779.1 - 0.097 12.3 0.3 0.52 10.0 0.0 2.3 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 KXZ50779.1 - 0.11 12.7 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXZ50779.1 - 0.11 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXZ50779.1 - 0.13 12.0 0.0 0.63 9.7 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 KXZ50779.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KXZ50779.1 - 0.16 11.0 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 KXZ50779.1 - 0.16 11.5 0.1 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXZ50779.1 - 0.17 11.4 0.0 0.5 9.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Guanylate_cyc PF00211.20 KXZ50780.1 - 7.4e-25 87.6 0.0 1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ribosomal_S30AE PF02482.19 KXZ50782.1 - 1.9e-07 31.8 0.1 2.5e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 KXZ50783.1 - 2e-19 69.0 0.2 3.7e-19 68.2 0.0 1.5 2 0 0 2 2 2 1 Sigma 54 modulation/S30EA ribosomal protein C terminus DAP_epimerase PF01678.19 KXZ50784.1 - 2.4e-62 208.5 0.0 5.9e-33 113.6 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase DUF3836 PF12930.7 KXZ50785.1 - 0.089 12.6 1.2 0.15 11.8 1.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF3836) GP38 PF05268.11 KXZ50785.1 - 2.2 7.9 19.2 0.63 9.7 0.3 2.1 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 IBR PF01485.21 KXZ50787.1 - 2.3e-16 59.7 14.6 2.7e-11 43.5 3.4 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain IBR PF01485.21 KXZ50788.1 - 3.2e-17 62.5 30.2 6.9e-11 42.2 1.2 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXZ50788.1 - 0.012 15.4 0.2 0.012 15.4 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ50788.1 - 0.053 13.5 0.1 0.053 13.5 0.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-trcl PF13451.6 KXZ50788.1 - 3 7.8 6.5 0.67 9.9 1.2 2.6 2 0 0 2 2 2 0 Probable zinc-ribbon domain Radical_SAM PF04055.21 KXZ50790.1 - 6.3e-06 26.7 0.8 0.0049 17.3 0.4 3.2 3 1 0 3 3 3 2 Radical SAM superfamily DEC-1_N PF04625.13 KXZ50790.1 - 0.0069 15.5 2.6 0.014 14.5 2.6 1.5 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Fer4_14 PF13394.6 KXZ50790.1 - 0.018 15.2 0.1 4.5 7.4 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain GRA6 PF05084.13 KXZ50794.1 - 0.012 15.6 1.4 0.025 14.5 1.4 1.6 1 0 0 1 1 1 0 Granule antigen protein (GRA6) PAS_4 PF08448.10 KXZ50794.1 - 0.097 12.9 0.0 0.52 10.6 0.0 2.0 2 0 0 2 2 2 0 PAS fold tRNA-synt_1b PF00579.25 KXZ50795.1 - 5.2e-57 193.4 0.0 6.7e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PsaD PF02531.16 KXZ50796.1 - 1.2e-65 219.2 0.0 1.4e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 PsaD SPAM PF02090.15 KXZ50797.1 - 0.011 15.5 0.6 0.016 15.0 0.6 1.2 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF2968 PF11180.8 KXZ50797.1 - 0.017 14.8 2.2 0.017 14.8 2.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF444 PF04285.12 KXZ50798.1 - 0.78 8.7 3.0 1.1 8.3 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Herpes_UL25 PF01499.16 KXZ50798.1 - 0.85 8.1 8.8 1.3 7.4 8.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family HET PF06985.11 KXZ50800.1 - 0.012 16.0 1.8 0.055 13.8 1.8 1.9 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXZ50802.1 - 7e-07 29.7 2.3 3.8e-06 27.3 2.3 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXZ50803.1 - 2.5e-08 34.4 0.9 4.3e-08 33.6 0.2 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) YjbH PF06082.11 KXZ50804.1 - 0.026 13.4 0.2 0.031 13.1 0.2 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF2797 PF10977.8 KXZ50804.1 - 0.076 12.9 0.5 0.096 12.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Peptidase_S46 PF10459.9 KXZ50804.1 - 0.17 10.5 2.8 0.2 10.3 2.8 1.1 1 0 0 1 1 1 0 Peptidase S46 DivIC PF04977.15 KXZ50804.1 - 0.24 11.2 5.6 0.49 10.2 5.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.11 KXZ50804.1 - 0.28 10.0 5.5 0.32 9.9 5.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 KXZ50804.1 - 0.61 10.2 9.5 0.87 9.7 9.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2058 PF09831.9 KXZ50804.1 - 0.74 10.0 7.6 0.97 9.6 7.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4337 PF14235.6 KXZ50804.1 - 1.8 8.6 8.4 2.9 8.0 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_13 PF13166.6 KXZ50804.1 - 3.9 6.0 7.3 5.1 5.6 7.3 1.0 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KXZ50806.1 - 1.5e-34 119.3 0.0 2.3e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ50806.1 - 2.4e-25 89.0 0.0 4.5e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BACK PF07707.15 KXZ50806.1 - 2e-05 24.6 0.0 5.4e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch ResIII PF04851.15 KXZ50806.1 - 0.057 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CDC45 PF02724.14 KXZ50806.1 - 4.8 5.4 10.4 7.3 4.8 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BACK PF07707.15 KXZ50807.1 - 4.2e-05 23.6 0.0 6.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 BTB And C-terminal Kelch BACK PF07707.15 KXZ50808.1 - 2.7e-05 24.2 0.1 6.9e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KXZ50811.1 - 8.9e-17 60.9 15.5 0.00034 20.8 0.1 6.4 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ50811.1 - 4.9e-16 58.4 2.1 0.0018 18.5 0.0 5.5 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KXZ50811.1 - 4.3e-15 55.4 13.6 0.00077 19.4 0.1 5.7 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KXZ50811.1 - 8.4e-09 35.1 0.1 0.00024 20.9 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KXZ50811.1 - 3.8e-08 32.8 7.3 0.0019 17.8 0.0 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 KXZ50811.1 - 0.00078 19.4 0.1 0.00078 19.4 0.1 5.2 6 0 0 6 6 6 1 Kelch motif bZIP_1 PF00170.21 KXZ50813.1 - 6.1e-13 48.7 14.4 9.1e-13 48.1 14.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ50813.1 - 2.5e-09 37.1 16.5 4.4e-09 36.3 16.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXZ50813.1 - 0.0015 19.0 8.5 0.0027 18.2 8.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.14 KXZ50813.1 - 0.011 16.1 0.1 0.22 11.9 1.4 2.4 3 0 0 3 3 3 0 Nnf1 TolA_bind_tri PF16331.5 KXZ50813.1 - 0.097 12.8 1.6 0.19 11.8 1.6 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Nucleotid_trans PF03407.16 KXZ50813.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase APG6_N PF17675.1 KXZ50813.1 - 0.25 11.9 4.5 0.4 11.2 4.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Shugoshin_N PF07558.11 KXZ50813.1 - 0.45 10.4 5.9 2 8.3 2.0 2.4 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region IMUP PF15761.5 KXZ50813.1 - 2.8 8.7 14.8 0.48 11.1 1.1 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein CDC45 PF02724.14 KXZ50813.1 - 5.8 5.1 8.0 7.8 4.7 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Secretin_N_2 PF07655.13 KXZ50813.1 - 8.1 7.1 8.2 1.3 9.6 0.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain TPR_2 PF07719.17 KXZ50814.1 - 6.5e-19 66.5 13.4 1.1e-05 25.2 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ50814.1 - 5e-15 54.6 5.0 0.00016 21.4 0.0 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ50814.1 - 1.9e-11 43.2 0.2 0.00071 19.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ50814.1 - 3e-10 39.6 1.2 0.03 14.0 0.0 4.7 3 1 2 5 5 5 3 TPR repeat TPR_16 PF13432.6 KXZ50814.1 - 5e-10 39.9 29.6 1.8e-08 34.8 8.4 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ50814.1 - 7.7e-10 38.8 2.9 4.8e-05 23.8 0.3 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ50814.1 - 9.9e-09 35.6 5.9 1.3e-05 25.6 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ50814.1 - 3.5e-07 30.2 0.1 1.1 9.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ50814.1 - 5.2e-06 26.5 24.6 0.026 14.6 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ50814.1 - 2.6e-05 24.4 0.1 2.6e-05 24.4 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ50814.1 - 6e-05 22.8 12.0 0.054 13.5 0.1 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ50814.1 - 0.00065 20.2 6.4 0.72 10.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ50814.1 - 0.0051 16.0 0.0 0.0051 16.0 0.0 1.8 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ50814.1 - 0.0083 16.3 1.2 0.18 12.1 0.8 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NYD-SP12_N PF15015.6 KXZ50814.1 - 0.1 10.9 0.6 0.14 10.5 0.6 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_10 PF13374.6 KXZ50814.1 - 0.17 11.8 0.2 0.17 11.8 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KXZ50814.1 - 0.19 11.4 0.2 2.4 7.8 0.1 2.4 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_4 PF07721.14 KXZ50814.1 - 0.9 10.3 0.0 0.9 10.3 0.0 6.0 5 2 0 5 5 3 0 Tetratricopeptide repeat TAF4 PF05236.14 KXZ50814.1 - 1.8 8.3 3.4 2.6 7.7 3.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BTAD PF03704.17 KXZ50814.1 - 7.1 7.1 17.3 0.055 13.9 3.7 3.1 2 1 1 3 3 2 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 KXZ50814.1 - 7.2 7.0 7.2 1.8 8.9 0.2 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat DUF1230 PF06799.11 KXZ50815.1 - 5.6e-20 71.9 0.4 3.8e-14 53.0 0.0 2.2 1 1 1 2 2 2 2 Conserved in the green lineage and diatoms 27 VIT1 PF01988.19 KXZ50817.1 - 3.1e-44 151.4 4.3 3.5e-44 151.2 4.3 1.0 1 0 0 1 1 1 1 VIT family COQ7 PF03232.13 KXZ50817.1 - 0.026 14.3 0.1 0.026 14.3 0.1 1.6 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Zn_Tnp_IS1595 PF12760.7 KXZ50818.1 - 0.084 12.9 1.6 0.13 12.2 1.6 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Helicase_C PF00271.31 KXZ50819.1 - 0.0084 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BACK PF07707.15 KXZ50820.1 - 2.8e-06 27.4 0.0 2.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Pkinase PF00069.25 KXZ50821.1 - 2.9e-22 79.3 0.0 4.1e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50821.1 - 1.6e-11 44.0 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 KXZ50821.1 - 8.5e-07 29.2 0.5 1.3e-05 25.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KXZ50821.1 - 3.1e-06 27.7 0.0 6.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ50821.1 - 8.7e-06 25.7 0.0 8.4e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXZ50821.1 - 3e-05 24.5 0.0 6.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ50821.1 - 0.00014 22.1 0.0 0.00035 20.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Kinase-like PF14531.6 KXZ50821.1 - 0.045 13.1 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KXZ50821.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 BBE PF08031.12 KXZ50823.1 - 3.8e-13 49.3 0.3 6.6e-13 48.5 0.3 1.3 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KXZ50823.1 - 9.4e-12 44.8 2.2 1.7e-11 44.0 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain Beta_helix PF13229.6 KXZ50824.1 - 3.8e-31 108.1 2.8 2.9e-16 59.7 0.5 3.4 3 1 1 4 4 4 3 Right handed beta helix region NosD PF05048.13 KXZ50824.1 - 2.3e-07 30.4 0.3 0.08 12.2 0.0 3.6 3 1 0 3 3 3 3 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KXZ50824.1 - 0.00041 19.8 0.6 0.013 14.9 0.0 3.5 5 0 0 5 5 5 1 Protein of unknown function (DUF1565) YopH_N PF09013.10 KXZ50824.1 - 0.034 14.4 0.0 15 5.9 0.0 2.4 1 1 1 2 2 2 0 YopH, N-terminal SPX PF03105.19 KXZ50824.1 - 0.27 11.1 4.0 0.39 10.6 4.0 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KXZ50824.1 - 9 5.0 9.5 13 4.5 9.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Beta_helix PF13229.6 KXZ50825.1 - 1.1e-30 106.6 4.3 9.2e-13 48.3 0.0 3.5 2 1 0 3 3 3 3 Right handed beta helix region NosD PF05048.13 KXZ50825.1 - 7.2e-06 25.4 3.4 1.1 8.5 0.4 3.9 2 2 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 KXZ50825.1 - 0.00022 21.1 6.3 0.25 11.1 0.1 3.9 3 1 0 3 3 3 2 Pectate lyase superfamily protein DUF4957 PF16318.5 KXZ50825.1 - 0.0051 16.7 0.0 0.44 10.5 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4957) DUF1565 PF07602.11 KXZ50825.1 - 0.0055 16.1 4.3 0.11 11.8 0.0 3.8 4 1 0 4 4 4 1 Protein of unknown function (DUF1565) Pentapeptide_4 PF13599.6 KXZ50825.1 - 0.16 12.2 0.3 8.4 6.7 0.0 2.7 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Adeno_E1B_55K PF01696.17 KXZ50825.1 - 0.32 9.6 1.1 0.95 8.1 0.0 1.9 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Ank_2 PF12796.7 KXZ50826.1 - 3.8e-32 110.7 2.3 2.8e-17 63.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Pkinase PF00069.25 KXZ50826.1 - 4.7e-31 108.1 0.0 6.8e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KXZ50826.1 - 4.6e-28 94.2 4.9 4.1e-05 23.6 0.1 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXZ50826.1 - 7.2e-27 92.6 9.5 4.3e-06 26.9 0.2 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXZ50826.1 - 1.9e-24 85.4 5.7 5.4e-08 33.0 0.5 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ50826.1 - 3e-23 81.9 3.1 8.2e-11 42.2 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 KXZ50826.1 - 1.4e-20 73.7 0.0 1.9e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ50826.1 - 0.00044 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF2384 PF09722.10 KXZ50826.1 - 0.033 14.2 2.2 5.3 7.2 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2384) Guanylate_cyc PF00211.20 KXZ50828.1 - 1e-53 181.7 0.0 1.6e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fer4_15 PF13459.6 KXZ50828.1 - 0.16 12.7 0.2 0.71 10.7 0.2 2.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain NTPase_1 PF03266.15 KXZ50829.1 - 1.9e-20 73.5 0.1 7.7e-17 61.7 0.0 2.0 1 1 1 2 2 2 2 NTPase AAA_22 PF13401.6 KXZ50829.1 - 9.1e-05 22.8 0.0 0.00017 21.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ50829.1 - 0.00034 21.1 0.1 0.0006 20.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXZ50829.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 KXZ50829.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXZ50829.1 - 0.0076 16.8 0.0 0.0076 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXZ50829.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 KXZ50829.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 KXZ50829.1 - 0.02 13.9 0.1 0.053 12.5 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KXZ50829.1 - 0.02 14.6 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXZ50829.1 - 0.026 14.9 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KXZ50829.1 - 0.035 14.5 0.0 0.095 13.1 0.0 1.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KXZ50829.1 - 0.039 14.4 0.0 0.07 13.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXZ50829.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KXZ50829.1 - 0.049 12.8 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 KXZ50829.1 - 0.059 13.5 0.0 0.086 12.9 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 KXZ50829.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXZ50829.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KXZ50829.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 KXZ50829.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KXZ50829.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXZ50829.1 - 0.13 12.7 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KXZ50829.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXZ50829.1 - 0.18 11.1 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Ceramidse_alk_C PF17048.5 KXZ50830.1 - 9.7e-23 80.9 0.0 1.2e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal MG2 PF01835.19 KXZ50830.1 - 0.08 13.4 0.0 0.11 12.9 0.0 1.3 1 1 0 1 1 1 0 MG2 domain Ceramidase_alk PF04734.13 KXZ50831.1 - 9.4e-175 582.1 0.0 2e-174 581.0 0.0 1.5 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KXZ50831.1 - 1.7e-11 44.2 0.0 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF5470 PF17564.2 KXZ50832.1 - 0.049 13.8 1.1 0.13 12.5 1.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5470) RVT_1 PF00078.27 KXZ50833.1 - 0.17 11.4 0.0 0.68 9.4 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5470 PF17564.2 KXZ50834.1 - 0.026 14.7 2.2 0.026 14.7 2.2 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5470) Fib_alpha PF08702.10 KXZ50834.1 - 0.089 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PCO_ADO PF07847.12 KXZ50834.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 PCO_ADO F_actin_bind PF08919.10 KXZ50834.1 - 4.7 7.3 7.2 2.7 8.1 0.1 3.2 3 1 1 4 4 4 0 F-actin binding IFRD PF05004.13 KXZ50834.1 - 6.4 5.8 13.4 3.6 6.6 10.9 1.7 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Pkinase_Tyr PF07714.17 KXZ50837.1 - 1.5e-48 165.4 0.0 2.9e-48 164.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50837.1 - 2.2e-32 112.5 0.0 2.9e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXZ50837.1 - 0.00019 20.9 0.0 0.00024 20.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ50837.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXZ50837.1 - 0.03 13.2 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain SOUL PF04832.12 KXZ50839.1 - 3.1e-15 56.8 0.0 3.8e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein APG6_N PF17675.1 KXZ50840.1 - 2.3e-05 24.9 10.9 2.3e-05 24.9 10.9 27.3 2 2 25 27 27 27 7 Apg6 coiled-coil region Lebercilin PF15619.6 KXZ50840.1 - 0.00019 21.2 18.7 0.00019 21.2 18.7 21.5 2 2 14 19 19 19 5 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 KXZ50840.1 - 0.00021 21.4 5.0 0.00021 21.4 5.0 25.1 3 2 19 24 24 24 11 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 KXZ50840.1 - 0.00057 18.7 24.4 0.00057 18.7 24.4 13.8 2 2 9 14 14 14 5 AAA domain DUF5082 PF16888.5 KXZ50840.1 - 0.0017 18.6 9.1 0.0017 18.6 9.1 21.8 9 5 10 21 21 21 3 Domain of unknown function (DUF5082) Mer2 PF09074.10 KXZ50841.1 - 0.00014 21.7 0.1 0.00019 21.3 0.1 1.2 1 0 0 1 1 1 1 Mer2 CALCOCO1 PF07888.11 KXZ50841.1 - 0.0023 16.9 0.2 0.0027 16.6 0.2 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C2H2_2 PF12756.7 KXZ50841.1 - 0.031 14.6 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Sec2p PF06428.11 KXZ50841.1 - 0.077 13.0 2.3 0.14 12.1 2.2 1.7 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p HAD_2 PF13419.6 KXZ50842.1 - 1.1e-26 94.0 0.0 1.3e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ50842.1 - 2.5e-14 54.1 0.3 7.4e-13 49.3 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ50842.1 - 0.0014 19.1 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXZ50842.1 - 0.15 12.1 0.0 1.2 9.3 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 KXZ50843.1 - 9.6e-19 67.7 0.0 1e-17 64.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50843.1 - 4.1e-08 32.9 0.0 1.9e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KXZ50843.1 - 0.93 10.5 2.9 11 7.1 0.1 4.1 3 1 0 3 3 3 0 WD domain, G-beta repeat L27_1 PF09058.10 KXZ50844.1 - 0.042 13.8 1.3 0.042 13.8 1.3 2.3 3 0 0 3 3 3 0 L27_1 DUF3584 PF12128.8 KXZ50844.1 - 0.065 10.7 25.2 0.079 10.5 25.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 KXZ50844.1 - 0.24 9.9 17.2 0.25 9.8 17.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family YscO PF07321.12 KXZ50844.1 - 0.59 10.1 38.4 2.1 8.3 12.4 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO TPR_MLP1_2 PF07926.12 KXZ50844.1 - 2.8 8.0 29.4 4.4 7.4 12.4 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KXZ50844.1 - 9.7 7.2 24.7 18 6.3 9.0 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain MutS_V PF00488.21 KXZ50845.1 - 6.8e-64 215.4 0.0 1.2e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXZ50845.1 - 1.2e-33 117.0 0.1 2.6e-33 115.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXZ50845.1 - 6.8e-16 58.5 0.1 1.5e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KXZ50845.1 - 1.3e-10 41.4 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KXZ50845.1 - 9.6e-05 22.7 0.0 0.0011 19.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain II YL1 PF05764.13 KXZ50845.1 - 0.0002 21.6 11.4 0.00048 20.3 11.4 1.7 1 0 0 1 1 1 1 YL1 nuclear protein AAA_23 PF13476.6 KXZ50845.1 - 0.092 13.2 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Myc_N PF01056.18 KXZ50845.1 - 0.14 12.1 3.0 0.33 10.8 3.0 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 KXZ50845.1 - 0.54 8.4 17.9 0.84 7.8 17.9 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KXZ50845.1 - 2.1 7.6 16.3 3.7 6.8 16.3 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KXZ50845.1 - 2.4 7.8 15.6 5.1 6.8 15.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KXZ50845.1 - 3.3 7.2 14.2 5.4 6.5 14.2 1.3 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 KXZ50845.1 - 8 4.6 12.5 12 4.0 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3707 PF12499.8 KXZ50846.1 - 1.2e-37 129.7 25.7 1.3e-22 80.9 11.8 2.4 2 1 0 2 2 2 2 Pherophorin Sod_Fe_C PF02777.18 KXZ50848.1 - 2.6e-30 104.6 0.0 3.8e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXZ50848.1 - 3.4e-09 37.0 1.9 1.1e-05 25.8 0.2 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, alpha-hairpin domain Exostosin PF03016.15 KXZ50850.1 - 3.8e-11 42.8 0.1 2.3e-10 40.2 0.1 1.9 1 1 0 1 1 1 1 Exostosin family Prok-JAB PF14464.6 KXZ50850.1 - 0.022 14.6 1.1 0.045 13.5 1.1 1.7 1 1 0 1 1 1 0 Prokaryotic homologs of the JAB domain CENP-T_C PF15511.6 KXZ50851.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50851.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ50851.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ50851.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50851.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ50851.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ50851.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ50852.1 - 2.7e-37 128.0 2.2 8.5e-37 126.4 2.2 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ50852.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ50852.1 - 0.00046 20.3 0.1 0.00078 19.5 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ50852.1 - 0.0034 17.6 0.5 0.009 16.3 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ50852.1 - 0.012 15.6 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LisH_2 PF16045.5 KXZ50853.1 - 4.7e-11 41.5 0.2 1.1e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 LisH Bap31_Bap29_C PF18035.1 KXZ50853.1 - 0.0054 16.7 3.4 3.9 7.6 0.1 4.2 4 0 0 4 4 4 2 Bap31/Bap29 cytoplasmic coiled-coil domain LisH PF08513.11 KXZ50853.1 - 0.01 15.8 0.3 0.027 14.5 0.3 1.8 1 0 0 1 1 1 0 LisH FOP_dimer PF09398.10 KXZ50853.1 - 0.066 13.5 0.5 0.19 12.0 0.1 2.0 2 0 0 2 2 2 0 FOP N terminal dimerisation domain FF PF01846.19 KXZ50854.1 - 4.9e-23 81.1 3.7 2.2e-09 37.4 0.1 5.8 5 0 0 5 5 5 5 FF domain WW PF00397.26 KXZ50854.1 - 4.2e-13 49.1 6.6 2.6e-06 27.4 0.5 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KXZ50854.1 - 0.016 15.9 0.0 0.13 12.9 0.0 2.5 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain adh_short PF00106.25 KXZ50855.1 - 5.5e-29 101.0 0.0 7e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ50855.1 - 1.3e-14 54.3 0.0 1.7e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ50855.1 - 0.0057 16.6 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 KR domain SET PF00856.28 KXZ50856.1 - 1.2e-14 55.0 0.0 1.5e-13 51.4 0.0 2.2 1 1 0 1 1 1 1 SET domain DUF2017 PF09438.10 KXZ50856.1 - 0.11 12.3 0.3 0.29 11.0 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2017) Ssu72 PF04722.13 KXZ50858.1 - 1.1e-64 217.5 0.0 1.2e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein ANAPC4_WD40 PF12894.7 KXZ50860.1 - 1.7e-10 41.0 0.1 7.4e-05 23.0 0.0 4.4 3 1 2 5 5 4 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KXZ50860.1 - 2.6e-10 39.6 33.5 0.11 12.7 0.3 10.3 10 1 1 11 11 11 4 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KXZ50860.1 - 2.1e-08 33.7 4.8 0.00028 20.1 0.0 4.3 3 2 1 4 4 4 2 Coatomer WD associated region Clathrin PF00637.20 KXZ50860.1 - 8e-07 29.0 5.4 0.93 9.4 0.0 5.9 5 1 0 5 5 5 2 Region in Clathrin and VPS TPR_7 PF13176.6 KXZ50860.1 - 1.7e-06 27.7 22.3 0.86 9.8 0.0 8.8 8 1 0 8 8 8 4 Tetratricopeptide repeat WD40 PF00400.32 KXZ50860.1 - 2.9e-05 24.7 0.8 1.5 9.9 0.1 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat TPR_1 PF00515.28 KXZ50860.1 - 0.00017 21.3 21.0 0.16 11.9 0.1 8.0 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ50860.1 - 0.00036 20.8 25.7 0.72 10.2 2.5 8.2 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ50860.1 - 0.0016 18.9 3.6 31 5.6 1.1 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ50860.1 - 0.008 16.9 40.4 3.9 8.6 0.2 11.6 10 1 3 13 13 13 1 Tetratricopeptide repeat SNAP PF14938.6 KXZ50860.1 - 0.013 15.0 25.9 0.23 10.9 0.8 4.9 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 KXZ50860.1 - 0.074 13.1 17.7 2.2 8.4 0.1 6.1 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain PPR_2 PF13041.6 KXZ50860.1 - 0.14 12.4 1.6 4.2 7.7 0.0 3.8 3 0 0 3 3 3 0 PPR repeat family ANAPC3 PF12895.7 KXZ50860.1 - 0.17 12.1 12.0 3.9 7.8 2.5 5.7 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Histone_H2A_C PF16211.5 KXZ50861.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ50861.1 - 1.7e-16 60.8 0.0 2.2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50861.1 - 5.9e-05 23.3 0.0 9.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50862.1 - 6.7e-22 78.3 4.6 9.1e-22 77.8 4.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50862.1 - 2.5e-05 24.4 0.1 8.3e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ50862.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ50862.1 - 0.016 15.3 4.7 0.029 14.4 4.7 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ50862.1 - 0.034 13.8 1.0 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ50862.1 - 2.5 8.7 9.8 7.4 7.1 9.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) CENP-T_C PF15511.6 KXZ50863.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50863.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ50863.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ50863.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50863.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ50863.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ50863.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated ArsB PF02040.15 KXZ50864.1 - 1.6e-21 77.1 14.9 8.1e-11 41.9 2.8 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 KXZ50864.1 - 9.6e-18 64.4 25.3 9.6e-18 64.4 25.3 2.2 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 KXZ50864.1 - 1.9e-07 30.5 5.4 1.9e-07 30.5 5.4 2.2 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region PseudoU_synth_2 PF00849.22 KXZ50865.1 - 2.1e-22 80.0 0.0 5e-22 78.7 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase Elf1 PF05129.13 KXZ50867.1 - 1.1e-26 92.7 1.7 1.2e-26 92.5 1.7 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like C1_1 PF00130.22 KXZ50867.1 - 0.033 14.1 1.2 0.058 13.3 1.2 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_4 PF13894.6 KXZ50867.1 - 1.2 10.1 6.5 9.6 7.4 1.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Tab2_like PF06485.11 KXZ50868.1 - 4.6e-92 308.3 0.0 5.3e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 Arm-DNA-bind_2 PF12167.8 KXZ50868.1 - 0.26 11.2 0.8 4.5 7.3 0.5 2.5 2 0 0 2 2 2 0 Arm DNA-binding domain HMG_box PF00505.19 KXZ50870.1 - 2.5e-16 59.8 2.0 1.9e-12 47.4 0.2 3.3 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KXZ50870.1 - 7.9e-12 45.6 1.9 1.4e-08 35.2 0.3 3.2 3 0 0 3 3 3 2 HMG-box domain Ccdc124 PF06244.12 KXZ50870.1 - 0.063 13.8 13.5 0.11 13.0 13.5 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 KXZ50870.1 - 0.42 11.2 17.8 47 4.5 17.8 2.1 1 1 0 1 1 1 0 YABBY protein TPT PF03151.16 KXZ50871.1 - 1.4e-12 47.6 18.3 1.6e-12 47.4 18.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ50871.1 - 0.57 10.3 28.7 0.97 9.6 14.1 2.5 2 1 0 2 2 2 0 EamA-like transporter family Histone_H2A_C PF16211.5 KXZ50872.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ50872.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50872.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50873.1 - 3.1e-22 79.4 3.4 4.2e-22 78.9 3.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50873.1 - 2.7e-05 24.3 0.1 8.3e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ50873.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ50873.1 - 0.024 14.7 4.2 0.048 13.7 4.2 1.6 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ50873.1 - 0.41 10.3 4.3 1.6 8.4 0.0 2.3 2 1 1 3 3 3 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ50873.1 - 1.2 9.7 8.1 2.5 8.6 8.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) CENP-T_C PF15511.6 KXZ50874.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50874.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ50874.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ50874.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50874.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ50874.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ50874.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated FUN14 PF04930.15 KXZ50875.1 - 8.8e-18 64.5 0.4 8.8e-18 64.5 0.4 1.9 2 0 0 2 2 2 1 FUN14 family EF-hand_5 PF13202.6 KXZ50875.1 - 0.0031 16.9 0.1 0.0049 16.3 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ50875.1 - 0.0039 16.6 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ50875.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 KXZ50875.1 - 0.028 14.6 0.1 0.043 14.0 0.1 1.2 1 0 0 1 1 1 0 Dockerin type I domain YIF1 PF03878.15 KXZ50876.1 - 1.2e-50 172.3 0.3 1.4e-50 172.0 0.3 1.0 1 0 0 1 1 1 1 YIF1 Histone PF00125.24 KXZ50877.1 - 2.8e-22 79.5 1.4 3.4e-22 79.2 1.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50877.1 - 2.7e-05 24.3 0.1 7.4e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KXZ50877.1 - 0.0011 19.1 0.9 0.0014 18.7 0.9 1.2 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 KXZ50877.1 - 0.0017 18.8 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ50877.1 - 0.023 14.4 0.3 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ50877.1 - 0.66 10.5 4.1 0.88 10.1 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3597 PF12200.8 KXZ50877.1 - 0.81 10.2 6.6 2 9.0 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) RNA_pol_Rpc4 PF05132.14 KXZ50877.1 - 7.6 7.0 8.4 15 6.0 8.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Histone_H2A_C PF16211.5 KXZ50878.1 - 2.2e-19 68.9 2.2 4.1e-19 68.0 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ50878.1 - 0.00055 20.3 0.0 0.15 12.4 0.0 2.1 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 Mak16 PF04874.14 KXZ50880.1 - 4e-25 88.3 21.7 4e-25 88.3 21.7 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.17 KXZ50880.1 - 4e-13 50.1 0.7 4e-13 50.1 0.7 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family BUD22 PF09073.10 KXZ50880.1 - 1.1e-05 25.0 19.4 1.3e-05 24.8 19.4 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 KXZ50880.1 - 0.0028 16.0 30.1 0.0043 15.3 30.1 1.2 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 KXZ50880.1 - 0.043 12.3 25.2 0.057 11.9 25.2 1.2 1 0 0 1 1 1 0 Mpp10 protein Exonuc_VII_L PF02601.15 KXZ50880.1 - 0.62 9.6 3.3 0.77 9.3 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIF_alpha PF05793.12 KXZ50880.1 - 3.7 6.0 32.3 6 5.3 32.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Fer2 PF00111.27 KXZ50881.1 - 3.1e-17 62.3 0.1 4.6e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 KXZ50881.1 - 0.048 13.7 0.5 0.08 13.0 0.5 1.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Biotin_lipoyl_2 PF13533.6 KXZ50881.1 - 0.89 9.4 3.3 1.9 8.4 2.9 1.7 1 1 1 2 2 2 0 Biotin-lipoyl like MOR2-PAG1_mid PF14228.6 KXZ50882.1 - 1.2e-123 413.9 0.2 7.7e-54 182.8 0.0 6.4 6 1 1 7 7 7 6 Cell morphogenesis central region MOR2-PAG1_N PF14222.6 KXZ50882.1 - 2.3e-31 109.4 0.0 3.7e-23 82.3 0.0 3.1 2 1 0 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KXZ50882.1 - 7.7e-05 22.7 0.0 0.68 9.7 0.0 2.8 2 0 0 2 2 2 2 Cell morphogenesis C-terminal Dynein_AAA_lid PF17852.1 KXZ50882.1 - 0.21 11.6 0.0 0.46 10.6 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain ATP-grasp_2 PF08442.10 KXZ50883.1 - 2.2e-57 193.9 0.1 5.8e-50 169.7 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain Ligase_CoA PF00549.19 KXZ50883.1 - 1.6e-25 89.7 4.1 2.7e-25 89.0 4.1 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KXZ50883.1 - 0.0012 18.4 0.2 0.52 9.7 0.0 2.4 2 1 0 2 2 2 2 ATP-grasp domain HCV_NS5a PF01506.19 KXZ50884.1 - 0.09 12.7 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor TcpS PF17456.2 KXZ50885.1 - 0.016 15.3 4.2 0.052 13.6 0.1 2.5 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S ANAPC4_WD40 PF12894.7 KXZ50886.1 - 1.2e-11 44.7 0.0 0.041 14.2 0.0 6.9 4 3 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KXZ50886.1 - 1.3e-11 44.6 16.1 0.018 14.9 0.0 8.9 5 3 4 9 9 9 4 Region in Clathrin and VPS WD40 PF00400.32 KXZ50886.1 - 2e-07 31.6 2.6 3.8 8.5 0.0 6.9 8 0 0 8 8 8 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXZ50886.1 - 4.1e-05 22.8 0.5 4.1e-05 22.8 0.5 4.4 5 1 1 6 6 6 1 Coatomer WD associated region IKI3 PF04762.12 KXZ50886.1 - 0.005 14.9 0.0 0.072 11.1 0.0 2.3 2 0 0 2 2 2 1 IKI3 family PPR PF01535.20 KXZ50886.1 - 0.0089 16.2 9.3 0.95 9.9 0.0 7.2 7 2 2 9 9 9 1 PPR repeat Ge1_WD40 PF16529.5 KXZ50886.1 - 0.0094 14.9 0.1 3.3 6.6 0.0 3.0 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 KXZ50886.1 - 0.015 15.3 0.1 0.097 12.7 0.0 2.4 3 0 0 3 3 3 0 WD domain, G-beta repeat ANAPC3 PF12895.7 KXZ50886.1 - 0.05 13.8 32.4 1.4 9.1 1.1 9.1 9 1 1 10 10 10 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.6 KXZ50886.1 - 1.1 9.5 5.2 11 6.3 0.0 5.0 5 0 0 5 5 5 0 PPR repeat family Sec16_C PF12931.7 KXZ50886.1 - 1.5 8.4 10.6 0.12 12.1 1.5 3.4 3 1 0 4 4 4 0 Sec23-binding domain of Sec16 DUF410 PF04190.13 KXZ50886.1 - 3.7 7.3 12.6 0.12 12.2 1.9 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF410) ASH PF15780.5 KXZ50888.1 - 1.4e-44 150.2 4.2 1.4e-05 25.2 0.0 13.8 15 0 0 15 15 15 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KXZ50888.1 - 4.3e-27 94.1 0.0 0.0028 17.5 0.0 7.9 8 0 0 8 8 8 5 MSP (Major sperm protein) domain PapD-like PF14874.6 KXZ50888.1 - 1.2e-12 47.9 1.6 0.065 13.4 0.0 8.9 9 0 0 9 9 9 2 Flagellar-associated PapD-like CH PF00307.31 KXZ50888.1 - 1.2e-09 38.3 0.3 3.2e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain TMEM131_like PF12371.8 KXZ50888.1 - 8.5e-07 29.1 1.9 7.5 6.9 0.0 6.8 7 0 0 7 7 7 2 Transmembrane protein 131-like DUF1573 PF07610.11 KXZ50888.1 - 7.2e-06 26.0 0.0 2.5 8.2 0.0 6.4 7 0 0 7 7 7 1 Protein of unknown function (DUF1573) DUF4139 PF13598.6 KXZ50888.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Transglut_C PF00927.22 KXZ50888.1 - 0.34 11.1 1.2 1.7e+02 2.4 0.0 5.0 7 0 0 7 7 7 0 Transglutaminase family, C-terminal ig like domain Glyoxalase PF00903.25 KXZ50889.1 - 0.00012 22.3 0.0 0.00028 21.1 0.0 1.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXZ50889.1 - 0.059 14.2 0.0 0.23 12.3 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain Pkinase_Tyr PF07714.17 KXZ50891.1 - 1.7e-34 119.3 0.0 2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ50891.1 - 2.2e-28 99.4 0.0 2.9e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ50891.1 - 0.0048 16.9 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ50891.1 - 0.0091 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1424 PF07232.11 KXZ50891.1 - 0.054 12.5 0.3 6.8 5.6 0.0 2.7 2 1 1 3 3 3 0 Putative rep protein (DUF1424) DUF4486 PF14858.6 KXZ50891.1 - 0.19 10.1 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) zf-met PF12874.7 KXZ50893.1 - 3.5e-05 24.0 1.8 6.9e-05 23.1 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXZ50893.1 - 0.016 15.5 0.3 0.032 14.5 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXZ50893.1 - 0.059 13.7 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PfkB PF00294.24 KXZ50894.1 - 2e-10 40.5 0.0 0.00064 19.1 0.0 3.1 2 1 1 3 3 3 3 pfkB family carbohydrate kinase Ribosomal_L14e PF01929.17 KXZ50895.1 - 1.3e-22 80.0 8.3 1.9e-22 79.5 8.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 GPAT_N PF14829.6 KXZ50895.1 - 0.076 13.0 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal V-SNARE_C PF12352.8 KXZ50896.1 - 4.5 7.6 18.4 2.2 8.6 0.9 4.9 6 0 0 6 6 6 0 Snare region anchored in the vesicle membrane C-terminus SMK-1 PF04802.15 KXZ50897.1 - 1.4e-48 165.3 1.0 2.9e-48 164.3 1.0 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 ParE_toxin PF05016.15 KXZ50897.1 - 0.097 13.3 0.7 0.32 11.6 0.1 2.3 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE PBP1_TM PF14812.6 KXZ50897.1 - 0.12 12.8 6.4 0.33 11.3 6.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNase_HII PF01351.18 KXZ50898.1 - 2.9e-36 125.2 0.0 3.5e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII DnaJ_C PF01556.18 KXZ50899.1 - 5.6e-40 136.8 0.0 8.1e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXZ50899.1 - 3.2e-23 81.6 1.6 5.1e-23 81.0 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXZ50899.1 - 3e-12 46.7 21.6 7.2e-12 45.5 21.6 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXZ50899.1 - 0.0045 16.9 13.2 0.17 11.9 2.0 2.8 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein C1_2 PF03107.16 KXZ50899.1 - 0.024 14.9 0.1 0.024 14.9 0.1 2.4 2 0 0 2 2 2 0 C1 domain DUF1860 PF08949.10 KXZ50899.1 - 0.029 14.1 0.8 0.052 13.3 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) zinc-ribbons_6 PF07191.12 KXZ50899.1 - 0.27 11.2 7.5 0.76 9.8 7.5 1.8 1 1 0 1 1 1 0 zinc-ribbons HypA PF01155.19 KXZ50899.1 - 0.76 9.8 10.7 1.8 8.6 1.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ank_5 PF13857.6 KXZ50900.1 - 8.2e-21 73.8 1.1 7.7e-11 42.0 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ50900.1 - 1e-20 74.1 0.2 4.6e-15 56.0 0.1 1.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ50900.1 - 1.4e-13 50.6 0.5 8.1e-05 22.9 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXZ50900.1 - 2.9e-12 45.6 0.1 6.9e-05 23.0 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXZ50900.1 - 5.2e-10 39.6 0.0 0.00011 22.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) STI1 PF17830.1 KXZ50900.1 - 1.6e-07 31.2 1.9 1.6e-07 31.2 1.9 2.5 1 1 1 2 2 2 1 STI1 domain GerD PF17898.1 KXZ50900.1 - 0.032 14.2 10.4 0.17 11.9 2.3 2.4 1 1 1 2 2 2 0 Spore germination GerD central core domain RGCC PF15151.6 KXZ50900.1 - 0.19 11.9 0.2 18 5.6 0.0 2.2 2 0 0 2 2 2 0 Response gene to complement 32 protein family Thioredoxin PF00085.20 KXZ50901.1 - 2.2e-16 59.7 0.0 2.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ50901.1 - 1.3e-08 35.3 0.0 1.8e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KXZ50901.1 - 1e-06 28.5 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KXZ50901.1 - 3.1e-06 27.4 0.0 0.00025 21.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXZ50901.1 - 4.4e-06 26.8 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KXZ50901.1 - 0.0013 18.6 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 KXZ50901.1 - 0.0031 17.4 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_4 PF13462.6 KXZ50901.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 KXZ50901.1 - 0.25 10.6 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family MSP PF01716.18 KXZ50902.1 - 1.8e-98 328.5 0.6 2.3e-98 328.2 0.6 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Ribosomal_L27e PF01777.18 KXZ50903.1 - 1.1e-32 112.2 8.5 1.6e-32 111.7 8.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KXZ50903.1 - 0.00014 21.7 0.5 0.00035 20.4 0.5 1.8 1 0 0 1 1 1 1 KOW motif FA_desaturase_2 PF03405.14 KXZ50904.1 - 1.4e-146 487.5 0.0 1.6e-146 487.3 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 KXZ50904.1 - 0.0067 16.8 0.0 3.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Rubrerythrin Pkinase PF00069.25 KXZ50905.1 - 2.2e-76 256.7 0.0 3.3e-76 256.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50905.1 - 1.3e-33 116.4 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 KXZ50905.1 - 1.6e-32 108.6 17.5 4.8e-09 35.1 1.6 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ50905.1 - 1.1e-26 93.0 4.3 2.9e-13 50.1 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ50905.1 - 3.2e-25 85.9 10.6 1.7e-06 27.4 0.1 4.9 3 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXZ50905.1 - 3e-21 73.9 18.2 1.4e-05 24.3 0.3 5.0 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 KXZ50905.1 - 1.7e-20 72.6 14.0 9.4e-10 38.2 0.6 4.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KXZ50905.1 - 1e-06 28.6 1.1 0.032 14.2 0.1 2.7 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.6 KXZ50905.1 - 1.7e-06 27.6 0.0 0.0003 20.2 0.0 2.6 2 1 0 2 2 2 1 Kinase-like C2 PF00168.30 KXZ50905.1 - 4.3e-06 27.0 0.0 5.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 C2 domain EF-hand_11 PF08976.11 KXZ50905.1 - 1.1e-05 26.2 0.0 6.7e-05 23.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXZ50905.1 - 0.0001 22.6 0.1 0.11 12.8 0.0 2.9 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KXZ50905.1 - 0.00022 21.5 0.2 0.95 9.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Kdo PF06293.14 KXZ50905.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sun2_CC2 PF18580.1 KXZ50905.1 - 0.074 13.3 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 Dockerin_1 PF00404.18 KXZ50905.1 - 0.13 12.5 3.4 3.2 8.0 0.3 3.3 1 1 2 3 3 3 0 Dockerin type I domain ERM PF00769.19 KXZ50906.1 - 0.0012 18.7 19.5 0.0012 18.7 19.5 9.8 2 1 6 9 9 9 3 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 KXZ50906.1 - 0.0066 16.5 3.3 0.0066 16.5 3.3 12.2 3 3 7 11 11 11 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 KXZ50906.1 - 0.022 14.6 0.3 0.022 14.6 0.3 10.9 5 4 6 11 11 11 0 Protein of unknown function (DUF724) MUG113 PF13455.6 KXZ50906.1 - 0.98 10.1 3.4 35 5.2 0.0 4.3 4 0 0 4 4 4 0 Meiotically up-regulated gene 113 Tropomyosin_1 PF12718.7 KXZ50906.1 - 7.8 6.6 134.2 0.099 12.8 6.8 12.1 3 1 8 13 13 13 0 Tropomyosin like DUF5582 PF17819.1 KXZ50907.1 - 0.00014 22.3 0.2 0.0002 21.8 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5582) Dpy-30 PF05186.13 KXZ50907.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Dpy-30 motif DUF5586 PF17824.1 KXZ50907.1 - 0.036 13.2 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) EF-hand_8 PF13833.6 KXZ50907.1 - 0.047 13.5 0.0 8.4 6.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 KXZ50907.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain pair Pribosyltran PF00156.27 KXZ50908.1 - 6.4e-18 64.8 0.1 8.4e-18 64.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXZ50908.1 - 0.0019 17.7 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KXZ50908.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase DEAD_2 PF06733.15 KXZ50909.1 - 2.1e-48 164.2 0.0 6.2e-48 162.7 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 KXZ50909.1 - 4.7e-42 144.0 0.2 8.4e-42 143.2 0.2 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 KXZ50909.1 - 6.2e-30 104.3 0.0 2e-26 92.8 0.0 2.6 1 1 1 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 KXZ50909.1 - 8.5e-08 32.4 0.1 3.3e-05 24.0 0.0 2.5 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KXZ50909.1 - 0.0013 18.6 0.1 0.081 12.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KXZ50909.1 - 0.0019 17.0 0.1 1.2 7.7 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain PNISR PF15996.5 KXZ50909.1 - 0.022 15.1 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR RhlB PF12300.8 KXZ50909.1 - 0.041 14.0 6.9 0.091 12.9 6.9 1.5 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB DUF2075 PF09848.9 KXZ50909.1 - 0.061 12.5 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KXZ50909.1 - 0.083 13.2 0.0 0.41 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXZ50909.1 - 0.22 11.3 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad21_Rec8 PF04824.16 KXZ50911.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Cu-binding_MopE PF11617.8 KXZ50912.1 - 0.00094 19.3 2.8 0.0021 18.2 2.8 1.6 1 0 0 1 1 1 1 Putative metal-binding motif Peptidase_M11 PF05548.11 KXZ50912.1 - 0.0086 15.3 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 LTV PF04180.14 KXZ50913.1 - 7.9e-14 52.2 21.4 6.5e-08 32.7 15.2 3.5 2 2 0 2 2 2 2 Low temperature viability protein Mpp10 PF04006.12 KXZ50913.1 - 0.0024 16.4 15.6 0.0042 15.6 15.6 1.3 1 0 0 1 1 1 1 Mpp10 protein PAN_4 PF14295.6 KXZ50913.1 - 0.0044 16.9 0.7 0.013 15.4 0.7 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXZ50913.1 - 0.012 15.6 1.1 0.029 14.3 1.1 1.6 1 0 0 1 1 1 0 PAN domain WSC PF01822.19 KXZ50913.1 - 0.022 14.9 1.9 0.24 11.6 0.0 2.7 2 0 0 2 2 2 0 WSC domain cNMP_binding PF00027.29 KXZ50914.1 - 7.8e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase PF00069.25 KXZ50915.1 - 6e-42 143.8 0.0 4.5e-40 137.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50915.1 - 4.7e-24 85.1 0.0 5.4e-22 78.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KXZ50915.1 - 5.2e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Proteasome PF00227.26 KXZ50916.1 - 4.6e-53 179.5 0.2 5.8e-53 179.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXZ50916.1 - 1.4e-15 56.6 0.1 2.7e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature U-box PF04564.15 KXZ50917.1 - 5.1e-13 49.0 0.0 9.3e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXZ50917.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Glyco_transf_4 PF13439.6 KXZ50917.1 - 0.042 13.8 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 FmiP_Thoc5 PF09766.9 KXZ50918.1 - 1.3e-72 245.1 0.0 1.6e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Cast PF10174.9 KXZ50918.1 - 0.019 13.2 5.8 0.027 12.7 5.8 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone RanGAP1_C PF07834.11 KXZ50918.1 - 0.054 13.1 0.2 0.093 12.3 0.2 1.3 1 0 0 1 1 1 0 RanGAP1 C-terminal domain NPV_P10 PF05531.12 KXZ50918.1 - 0.12 12.8 1.6 0.53 10.8 1.6 2.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KXZ50918.1 - 0.14 12.2 1.5 0.18 11.8 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXZ50918.1 - 0.32 9.8 10.3 0.19 10.6 2.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein RmuC PF02646.16 KXZ50918.1 - 0.77 8.8 8.3 3 6.9 3.0 2.2 2 0 0 2 2 2 0 RmuC family PRKG1_interact PF15898.5 KXZ50918.1 - 6 7.8 12.0 1.9 9.5 2.3 2.7 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain FA_desaturase PF00487.24 KXZ50920.1 - 0.007 16.2 8.5 0.007 16.2 8.5 1.6 1 1 1 2 2 2 2 Fatty acid desaturase AA_kinase PF00696.28 KXZ50921.1 - 1.4e-29 103.4 1.0 4.2e-25 88.7 0.0 2.3 1 1 1 2 2 2 2 Amino acid kinase family PUA PF01472.20 KXZ50921.1 - 1.8e-14 53.5 0.1 6.9e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 PUA domain PUA_3 PF17785.1 KXZ50921.1 - 0.009 15.8 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 PUA-like domain HEM4 PF02602.15 KXZ50921.1 - 0.048 13.0 0.1 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD AA_kinase PF00696.28 KXZ50922.1 - 2.9e-41 141.7 0.1 4e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KXZ50922.1 - 9e-18 64.0 0.1 4.2e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 PUA domain PUA_3 PF17785.1 KXZ50922.1 - 0.00032 20.5 0.0 0.00076 19.2 0.0 1.7 1 0 0 1 1 1 1 PUA-like domain PLAC8 PF04749.17 KXZ50923.1 - 1.5e-12 48.4 6.2 2e-12 48.0 6.2 1.2 1 0 0 1 1 1 1 PLAC8 family Chlorovi_GP_rpt PF06598.11 KXZ50925.1 - 0.7 10.0 9.1 2 8.5 0.4 2.4 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat Neur_chan_LBD PF02931.23 KXZ50926.1 - 1.4e-10 41.0 0.5 1.1e-09 38.0 0.5 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KXZ50926.1 - 2.9e-07 30.8 11.5 3.8e-06 27.2 11.5 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Pkinase_Tyr PF07714.17 KXZ50928.1 - 1.5e-06 27.7 0.0 0.00031 20.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ50928.1 - 2.5e-05 23.8 0.0 0.064 12.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Neur_chan_memb PF02932.16 KXZ50929.1 - 8.8e-16 58.7 19.3 4.9e-09 36.6 0.0 3.2 3 1 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KXZ50929.1 - 1.1e-14 54.4 0.2 8.7e-06 25.3 0.0 2.8 2 1 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain TMEM135_C_rich PF15982.5 KXZ50929.1 - 2.1e-06 28.4 0.7 0.016 15.8 0.0 3.2 2 0 0 2 2 2 2 N-terminal cysteine-rich region of Transmembrane protein 135 TRIC PF05197.13 KXZ50929.1 - 0.16 11.5 9.4 2.5 7.6 1.5 2.6 2 0 0 2 2 2 0 TRIC channel HRM PF02793.22 KXZ50929.1 - 1.5 9.2 9.1 22 5.5 2.3 3.9 3 1 0 3 3 3 0 Hormone receptor domain RRM_1 PF00076.22 KXZ50931.1 - 1.2e-14 53.9 1.5 7e-08 32.2 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ50931.1 - 0.00038 20.5 0.0 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif CRISPR_Cse1 PF09481.10 KXZ50932.1 - 0.059 12.5 3.4 0.1 11.6 3.4 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) SKA1 PF07160.12 KXZ50932.1 - 0.079 12.8 2.1 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 V-SNARE PF05008.15 KXZ50932.1 - 0.55 10.6 2.7 18 5.8 0.4 2.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.12 KXZ50932.1 - 2 8.9 3.9 76 3.9 0.1 3.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KXZ50932.1 - 3 7.9 5.4 3 7.9 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF393 PF04134.12 KXZ50933.1 - 2.9e-25 89.8 0.0 4.3e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF393 BDV_P10 PF06515.11 KXZ50933.1 - 4.9 7.3 5.9 6.5 6.9 2.3 2.8 2 1 1 3 3 3 0 Borna disease virus P10 protein Rad51 PF08423.11 KXZ50936.1 - 4.6e-120 399.6 0.1 6.3e-120 399.2 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXZ50936.1 - 4.1e-10 39.6 0.2 5.8e-10 39.1 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KXZ50936.1 - 1.1e-09 38.1 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KXZ50936.1 - 4.1e-07 29.6 0.2 1.8e-06 27.5 0.2 2.0 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KXZ50936.1 - 3.8e-06 27.4 1.7 2.3e-05 24.9 0.2 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_24 PF13479.6 KXZ50936.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXZ50936.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea LRR_8 PF13855.6 KXZ50937.1 - 1.2e-17 63.4 16.4 5.7e-09 35.6 2.8 4.2 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KXZ50937.1 - 4e-17 62.0 8.9 6.6e-05 23.2 0.8 5.0 3 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ50937.1 - 0.018 15.1 7.8 4.1 7.7 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat VIR_N PF15912.5 KXZ50937.1 - 0.12 12.0 4.4 0.2 11.3 4.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal LRR_1 PF00560.33 KXZ50937.1 - 0.17 12.5 9.8 1.8e+02 3.4 0.0 6.1 7 1 0 7 7 7 0 Leucine Rich Repeat Spc7 PF08317.11 KXZ50937.1 - 1.8 7.4 20.3 1.3 7.9 0.3 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein ThiF PF00899.21 KXZ50938.1 - 4e-30 105.0 0.8 6e-29 101.1 0.8 2.2 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KXZ50938.1 - 0.026 14.8 1.1 0.47 10.7 0.3 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXZ50938.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AP2 PF00847.20 KXZ50939.1 - 2.4e-12 46.9 0.7 3.9e-12 46.2 0.7 1.4 1 0 0 1 1 1 1 AP2 domain SPC22 PF04573.12 KXZ50940.1 - 2e-43 147.8 0.0 2.7e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit ABC_tran PF00005.27 KXZ50941.1 - 1.1e-12 48.6 0.0 1.8e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXZ50941.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXZ50941.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXZ50941.1 - 0.039 13.7 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXZ50941.1 - 0.041 14.2 0.0 0.059 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ50941.1 - 0.087 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXZ50941.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KXZ50941.1 - 0.19 11.0 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_PrkA PF08298.11 KXZ50941.1 - 0.2 10.5 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Pkinase PF00069.25 KXZ50942.1 - 1.4e-14 54.2 0.0 2.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ50942.1 - 4.1e-13 49.2 0.0 1.2e-12 47.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXZ50942.1 - 0.0099 15.8 0.7 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ammonium_transp PF00909.21 KXZ50943.1 - 1.8e-93 313.4 25.9 2e-93 313.2 25.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Nic96 PF04097.14 KXZ50944.1 - 5.7e-51 173.7 0.0 6.7e-35 120.6 0.0 2.5 3 0 0 3 3 3 2 Nup93/Nic96 Thioredoxin PF00085.20 KXZ50945.1 - 1.4e-05 25.0 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PcfJ PF14284.6 KXZ50945.1 - 0.056 13.3 0.9 0.099 12.5 0.9 1.6 1 1 0 1 1 1 0 PcfJ-like protein CAF1-p150_N PF15557.6 KXZ50946.1 - 0.24 11.3 7.0 0.075 13.0 2.8 1.9 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to PCNA DUF4611 PF15387.6 KXZ50946.1 - 2.2 8.6 8.6 2.7 8.3 1.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) RINGv PF12906.7 KXZ50948.1 - 8.6e-08 32.2 6.8 1.5e-07 31.4 6.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXZ50948.1 - 0.094 13.1 9.0 0.23 11.9 9.0 1.7 1 0 0 1 1 1 0 Ring finger domain Amino_oxidase PF01593.24 KXZ50949.1 - 8.4e-23 81.4 0.1 1.1e-22 81.0 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ50949.1 - 2e-11 43.9 1.6 6.2e-11 42.4 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ50949.1 - 2.8e-08 33.3 1.1 1.1e-05 24.8 0.7 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ50949.1 - 3.7e-08 33.3 7.8 1.3e-06 28.3 7.8 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ50949.1 - 1e-06 28.2 3.3 2.2e-06 27.0 3.3 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXZ50949.1 - 8.3e-06 24.7 0.4 0.0007 18.4 0.7 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXZ50949.1 - 1.2e-05 24.9 1.9 2e-05 24.2 1.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXZ50949.1 - 0.00031 20.1 1.0 0.00051 19.4 1.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXZ50949.1 - 0.00045 19.4 1.9 0.00045 19.4 1.9 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXZ50949.1 - 0.0031 16.8 0.5 0.0031 16.8 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KXZ50949.1 - 0.004 17.7 1.3 0.006 17.1 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ50949.1 - 0.0076 15.5 0.6 0.012 14.9 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXZ50949.1 - 0.021 15.2 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 KXZ50949.1 - 0.046 13.0 0.3 0.075 12.3 0.3 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KXZ50949.1 - 0.05 12.4 0.4 0.073 11.9 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KXZ50949.1 - 0.076 12.1 0.6 0.11 11.5 0.6 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KXZ50949.1 - 0.14 12.1 0.9 0.21 11.5 0.9 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KXZ50950.1 - 8.2e-19 67.8 0.0 1.6e-10 40.5 0.0 2.5 2 1 1 3 3 3 2 RmlD substrate binding domain Epimerase PF01370.21 KXZ50950.1 - 2.8e-10 40.1 0.1 4.5e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ50950.1 - 1.9e-07 30.8 0.0 4.4e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KXZ50950.1 - 0.0014 18.9 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KXZ50950.1 - 0.0017 18.3 0.2 0.011 15.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXZ50950.1 - 0.045 12.9 0.7 0.92 8.6 0.7 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1754 PF08555.10 KXZ50951.1 - 0.25 12.2 13.3 0.52 11.1 13.3 1.6 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Histone PF00125.24 KXZ50952.1 - 1.7e-21 76.9 5.0 2.4e-21 76.4 5.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50952.1 - 8.2e-05 22.8 0.1 8.2e-05 22.8 0.1 2.1 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ50952.1 - 0.0019 18.7 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ50952.1 - 0.024 14.6 7.2 0.056 13.5 7.2 1.6 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ50952.1 - 0.031 13.9 1.2 1.1 8.8 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ50952.1 - 1.6 9.3 8.6 3.8 8.0 8.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) CENP-T_C PF15511.6 KXZ50953.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50953.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ50953.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ50953.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50953.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ50953.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ50953.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated AA_kinase PF00696.28 KXZ50954.1 - 1.5e-10 41.1 0.4 5.5e-10 39.2 0.4 1.8 1 1 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 KXZ50954.1 - 1.4e-09 38.2 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ50954.1 - 6.6e-06 26.5 0.0 2.1e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ50954.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXZ50954.1 - 0.071 13.2 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RCDG1 PF15725.5 KXZ50955.1 - 1.4 9.4 12.4 0.13 12.7 7.1 2.0 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein Histone PF00125.24 KXZ50956.1 - 3.1e-47 160.2 0.7 3.3e-47 160.1 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ50956.1 - 7.9e-05 23.0 0.0 0.00011 22.6 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ50956.1 - 0.00025 21.2 0.1 0.00031 20.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ50956.1 - 0.003 17.8 0.1 0.0042 17.3 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ50956.1 - 0.006 16.6 0.0 0.0082 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF4201 PF13870.6 KXZ50957.1 - 1.1e-34 119.7 18.4 1.1e-34 119.7 18.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) GRP PF07172.11 KXZ50957.1 - 0.047 14.4 17.4 2.7 8.7 0.2 2.5 2 0 0 2 2 2 0 Glycine rich protein family TRAF_BIRC3_bd PF16673.5 KXZ50957.1 - 0.86 9.4 5.6 1.1 9.1 0.6 3.3 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF1664 PF07889.12 KXZ50957.1 - 1.6 8.8 10.8 1.3 9.0 2.1 3.2 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXZ50957.1 - 3.1 6.6 18.9 3.2 6.6 9.2 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 KXZ50958.1 - 0.012 16.1 15.1 0.012 16.1 15.1 2.8 1 1 1 2 2 2 0 Fez1 CRAL_TRIO PF00650.20 KXZ50959.1 - 1.4e-28 99.7 0.0 1.6e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXZ50959.1 - 0.063 13.4 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2497 PF10691.9 KXZ50960.1 - 7.6 7.1 10.6 21 5.7 0.0 4.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2497) Histone PF00125.24 KXZ50962.1 - 1.1e-36 126.1 0.2 1.3e-36 125.9 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ50962.1 - 7.2e-05 23.1 0.0 9.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ50962.1 - 0.00026 21.1 0.1 0.0003 20.9 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KXZ50962.1 - 0.0061 16.6 0.0 0.0076 16.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KXZ50962.1 - 0.01 16.1 0.1 0.013 15.8 0.1 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF746 PF05344.11 KXZ50962.1 - 0.095 12.5 0.8 0.14 12.0 0.1 1.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF746) CENP-T_C PF15511.6 KXZ50963.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ50963.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ50963.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ50963.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ50963.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ50963.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ50963.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ50964.1 - 8.3e-21 74.7 8.9 1.2e-20 74.2 8.9 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50964.1 - 8.3e-05 22.8 0.1 8.3e-05 22.8 0.1 2.2 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ50964.1 - 0.0019 18.7 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ50964.1 - 0.043 13.8 7.9 0.094 12.8 8.0 1.6 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ50964.1 - 0.063 12.9 2.2 1.2 8.8 0.0 2.4 1 1 2 3 3 3 0 Replication protein C N-terminal domain Tim54 PF11711.8 KXZ50964.1 - 0.76 8.5 7.6 0.82 8.4 7.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3391 PF11871.8 KXZ50964.1 - 3.3 8.3 10.4 9.1 6.8 10.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone_H2A_C PF16211.5 KXZ50965.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ50965.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50965.1 - 3.6e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone O-FucT PF10250.9 KXZ50966.1 - 1.3e-07 31.7 0.0 0.00051 19.8 0.0 3.1 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Ank_2 PF12796.7 KXZ50967.1 - 0.0067 17.0 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ50967.1 - 0.009 16.3 0.3 0.022 15.1 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ50967.1 - 0.045 14.3 0.2 0.29 11.8 0.2 2.4 1 0 0 1 1 1 0 Ankyrin repeat TatD_DNase PF01026.21 KXZ50968.1 - 4.8e-34 117.9 0.0 6.9e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase zf_UBZ PF18439.1 KXZ50969.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DSPc PF00782.20 KXZ50969.1 - 0.024 14.5 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF1610 PF07754.11 KXZ50969.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) IPPT PF01715.17 KXZ50970.1 - 8.6e-39 133.7 0.0 2.3e-38 132.3 0.0 1.6 1 1 0 1 1 1 1 IPP transferase IPT PF01745.16 KXZ50970.1 - 0.0014 18.1 0.2 4.2 6.7 0.0 3.3 3 1 0 3 3 3 2 Isopentenyl transferase AAA_18 PF13238.6 KXZ50970.1 - 0.0021 18.6 0.4 0.024 15.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ50970.1 - 0.069 13.5 0.1 0.069 13.5 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KXZ50970.1 - 0.16 11.3 0.2 0.28 10.4 0.2 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_26 PF13500.6 KXZ50970.1 - 0.23 11.2 0.2 0.38 10.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain Histone PF00125.24 KXZ50972.1 - 2.8e-41 140.9 0.7 3.3e-41 140.7 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ50972.1 - 5.8e-05 23.4 0.1 6.9e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ50972.1 - 0.0002 21.5 0.1 0.00025 21.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ50972.1 - 0.0023 18.2 0.1 0.0033 17.7 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ50972.1 - 0.0043 17.1 0.0 0.0062 16.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KXZ50973.1 - 8.6e-22 77.9 4.4 1.2e-21 77.4 4.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50973.1 - 2.5e-05 24.5 0.1 8.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ50973.1 - 0.0019 18.7 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ50973.1 - 0.03 14.0 0.7 0.51 10.0 0.1 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ50973.1 - 0.035 14.1 6.6 0.089 12.8 6.6 1.7 1 1 0 1 1 1 0 YscO-like protein DUF3391 PF11871.8 KXZ50973.1 - 3 8.4 9.1 7.2 7.1 9.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone_H2A_C PF16211.5 KXZ50974.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ50974.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ50974.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LON_substr_bdg PF02190.16 KXZ50975.1 - 1e-18 68.0 0.0 1.6e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain TPR_1 PF00515.28 KXZ50975.1 - 3.7e-11 42.3 0.8 8.1e-05 22.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ50975.1 - 2.8e-10 39.5 3.9 6.7e-05 22.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 KXZ50975.1 - 5.1e-09 35.8 12.9 8.4e-09 35.1 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ50975.1 - 8.7e-07 28.7 9.9 1.4e-06 28.0 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ50975.1 - 1.3e-06 28.6 14.1 2.9e-06 27.5 14.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 KXZ50975.1 - 1.1e-05 25.5 6.4 1.9e-05 24.7 6.4 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 KXZ50975.1 - 1.9e-05 24.4 12.2 3.5e-05 23.6 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.6 KXZ50975.1 - 2.2e-05 24.3 0.2 0.017 15.3 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat Prok-RING_4 PF14447.6 KXZ50975.1 - 5.5e-05 22.9 11.0 9.1e-05 22.2 11.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXZ50975.1 - 9.8e-05 22.3 12.2 0.00019 21.4 12.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ50975.1 - 0.00011 22.1 12.3 0.00019 21.3 12.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 KXZ50975.1 - 0.00046 19.8 0.1 0.65 9.7 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 KXZ50975.1 - 0.00059 20.1 5.3 0.11 12.8 1.5 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 KXZ50975.1 - 0.00063 19.8 11.2 0.0014 18.7 11.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TPR_14 PF13428.6 KXZ50975.1 - 0.03 15.1 14.9 0.18 12.7 0.2 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 KXZ50975.1 - 0.041 13.7 10.7 0.079 12.8 10.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain U-box PF04564.15 KXZ50975.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.7 KXZ50975.1 - 0.27 11.6 10.4 0.57 10.5 10.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_9 PF13371.6 KXZ50975.1 - 1 9.5 6.8 6.9 6.9 0.4 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-Nse PF11789.8 KXZ50975.1 - 1.3 8.9 4.7 2.8 7.8 4.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3138 PF11336.8 KXZ50975.1 - 1.8 7.1 9.2 3 6.4 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SNF5 PF04855.12 KXZ50978.1 - 0.00089 19.1 0.0 0.00089 19.1 0.0 4.5 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 Proteasome PF00227.26 KXZ50979.1 - 3.3e-48 163.7 0.0 4.3e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXZ50979.1 - 1e-11 44.2 0.4 1e-11 44.2 0.4 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Cut12 PF11500.8 KXZ50979.1 - 0.11 12.5 0.0 0.27 11.2 0.1 1.6 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Cementoin PF10511.9 KXZ50980.1 - 0.14 12.4 0.6 0.36 11.2 0.6 1.6 1 0 0 1 1 1 0 Trappin protein transglutaminase binding domain ABC_membrane PF00664.23 KXZ50983.1 - 5.9e-31 108.1 0.0 8.9e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ50983.1 - 1.7e-23 83.7 0.0 7.6e-23 81.5 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ50983.1 - 0.00086 19.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ50983.1 - 0.0041 16.6 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXZ50983.1 - 0.0062 16.9 4.4 0.012 16.0 2.7 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KXZ50983.1 - 0.0066 16.2 1.1 0.035 13.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 KXZ50983.1 - 0.014 15.4 0.1 0.035 14.2 0.1 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 KXZ50983.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXZ50983.1 - 0.032 14.0 0.0 0.096 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 KXZ50983.1 - 0.041 13.5 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 KXZ50983.1 - 0.042 12.8 0.0 0.066 12.1 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KXZ50983.1 - 0.051 13.6 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KXZ50983.1 - 0.053 12.9 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KXZ50983.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXZ50983.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXZ50983.1 - 0.22 11.0 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_membrane PF00664.23 KXZ50984.1 - 6e-12 45.8 0.4 6e-12 45.8 0.4 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ50984.1 - 0.00019 22.0 0.0 0.00032 21.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KXZ50984.1 - 0.0013 18.3 0.4 0.0043 16.6 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXZ50984.1 - 0.0015 18.3 0.1 0.0044 16.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KXZ50984.1 - 0.085 13.3 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXZ50984.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXZ50984.1 - 0.15 11.9 0.4 1.2 9.0 0.2 2.0 2 0 0 2 2 2 0 RsgA GTPase Sulfotransfer_4 PF17784.1 KXZ50985.1 - 1.1e-52 179.0 0.0 2e-52 178.1 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ50985.1 - 0.0095 16.3 0.2 0.038 14.4 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase family Acetate_kinase PF00871.17 KXZ50987.1 - 7.6e-82 275.1 0.0 9.6e-82 274.7 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Trypsin_2 PF13365.6 KXZ50988.1 - 1.3e-11 45.6 3.4 5.4e-09 37.1 3.4 2.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXZ50988.1 - 0.04 13.7 0.2 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Trypsin RPAP3_C PF13877.6 KXZ50990.1 - 1.4e-14 54.3 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 WD40 PF00400.32 KXZ50992.1 - 4.2e-13 49.5 14.4 0.00027 21.7 1.7 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 KXZ50992.1 - 0.051 12.2 1.1 6.3 5.3 0.0 2.6 2 1 0 3 3 3 0 Nucleoporin Nup120/160 TPPII_N PF12583.8 KXZ50992.1 - 4.9 7.7 9.1 9.3 6.8 9.1 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal AAA PF00004.29 KXZ50993.1 - 2.2e-41 141.4 0.0 3.9e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ50993.1 - 1e-11 44.4 0.2 2.4e-11 43.2 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KXZ50993.1 - 1e-09 38.2 0.6 2.5e-09 37.0 0.6 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KXZ50993.1 - 2e-07 31.5 0.0 0.00023 21.6 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KXZ50993.1 - 5e-06 26.3 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXZ50993.1 - 1.7e-05 24.9 0.0 0.00022 21.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXZ50993.1 - 7e-05 23.0 0.0 0.00027 21.1 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXZ50993.1 - 0.00018 21.8 0.1 0.022 15.0 0.0 2.8 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.13 KXZ50993.1 - 0.001 18.3 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXZ50993.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KXZ50993.1 - 0.0024 17.1 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 KXZ50993.1 - 0.0026 17.4 0.3 0.0072 16.0 0.1 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 KXZ50993.1 - 0.0029 18.0 0.0 0.007 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KXZ50993.1 - 0.0037 17.8 0.0 0.019 15.5 0.0 2.2 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXZ50993.1 - 0.004 16.9 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXZ50993.1 - 0.0049 16.3 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KXZ50993.1 - 0.0061 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KXZ50993.1 - 0.0075 16.0 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KXZ50993.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KXZ50993.1 - 0.013 15.2 0.0 0.081 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KXZ50993.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXZ50993.1 - 0.016 15.2 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXZ50993.1 - 0.025 14.9 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXZ50993.1 - 0.026 13.9 0.1 0.2 11.0 0.0 2.3 3 0 0 3 3 2 0 KaiC AAA_33 PF13671.6 KXZ50993.1 - 0.037 14.2 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ50993.1 - 0.042 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Phage_GP20 PF06810.11 KXZ50993.1 - 0.043 13.6 1.4 2.4 7.9 1.3 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 AAA_30 PF13604.6 KXZ50993.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ50993.1 - 0.073 13.6 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 1 0 ABC transporter ATPase_2 PF01637.18 KXZ50993.1 - 0.077 12.9 0.1 0.29 11.0 0.0 2.0 2 1 0 2 2 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KXZ50993.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KXZ50993.1 - 0.1 12.3 0.5 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.12 KXZ50993.1 - 0.13 12.4 0.9 0.23 11.5 0.9 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_25 PF13481.6 KXZ50993.1 - 0.13 11.8 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.16 KXZ50993.1 - 0.16 12.5 0.8 0.76 10.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 GP41 PF00517.17 KXZ50993.1 - 0.19 11.6 0.0 0.43 10.5 0.0 1.6 2 0 0 2 2 1 0 Retroviral envelope protein DUF4140 PF13600.6 KXZ50993.1 - 0.19 12.2 1.0 0.61 10.6 1.0 1.9 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) LOH1CR12 PF10158.9 KXZ50993.1 - 0.19 11.8 0.3 0.39 10.8 0.3 1.5 1 0 0 1 1 1 0 Tumour suppressor protein AAA_13 PF13166.6 KXZ50993.1 - 1.1 7.9 2.8 6 5.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain IDO PF01231.18 KXZ50994.1 - 8.4e-31 107.2 0.0 7.2e-28 97.5 0.0 2.1 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase PQQ PF01011.21 KXZ50995.1 - 0.0034 17.3 0.3 0.049 13.6 0.0 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 KXZ50995.1 - 0.16 12.5 5.2 0.17 12.4 0.3 3.5 4 0 0 4 4 4 0 PQQ-like domain JmjC PF02373.22 KXZ50996.1 - 3e-36 124.3 0.1 5e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KXZ50996.1 - 0.013 15.5 1.6 0.013 15.5 1.6 1.8 2 0 0 2 2 2 0 jmjN domain Pep1_7 PF17232.2 KXZ50996.1 - 0.049 14.1 0.4 0.049 14.1 0.4 4.2 3 2 2 5 5 5 0 Elicitor peptide 1-7 CbiG_mid PF11761.8 KXZ50996.1 - 0.086 13.0 0.3 0.53 10.4 0.3 2.4 1 0 0 1 1 1 0 Cobalamin biosynthesis central region FMO-like PF00743.19 KXZ50998.1 - 1.1e-26 93.4 0.0 2e-11 43.0 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXZ50998.1 - 4.5e-07 29.4 0.0 0.00017 21.0 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ50998.1 - 0.00044 19.6 0.0 0.058 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ50998.1 - 0.0051 16.0 0.0 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXZ50998.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXZ50998.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PAP_fibrillin PF04755.12 KXZ50999.1 - 3.5e-12 46.7 0.0 5.7e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 PAP_fibrillin SATase_N PF06426.14 KXZ51000.1 - 5e-39 132.9 0.2 5e-39 132.9 0.2 1.6 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 KXZ51000.1 - 1.2e-11 43.8 7.7 1.6e-07 30.7 0.8 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ51000.1 - 2.8e-06 27.0 11.7 5.2e-05 22.9 1.8 2.6 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase TFIIA PF03153.13 KXZ51000.1 - 0.72 9.8 5.1 1 9.3 5.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 KXZ51001.1 - 3.7e-38 128.8 15.1 1.6e-09 38.2 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51001.1 - 2.8e-10 40.3 2.9 0.014 15.7 0.1 5.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ51001.1 - 5.1e-07 29.0 2.0 0.19 10.6 0.0 4.5 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXZ51001.1 - 0.00011 21.0 8.7 0.22 10.1 0.2 4.2 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXZ51001.1 - 0.00041 19.2 0.3 1.1 8.0 0.0 3.7 1 1 1 3 3 3 2 Nup133 N terminal like VID27 PF08553.10 KXZ51001.1 - 0.0013 17.8 0.0 0.0028 16.8 0.0 1.4 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain Frtz PF11768.8 KXZ51001.1 - 0.065 11.5 0.0 0.12 10.6 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KXZ51001.1 - 0.08 11.8 0.2 0.08 11.8 0.2 2.4 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain TPMT PF05724.11 KXZ51001.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Hira PF07569.11 KXZ51001.1 - 0.16 11.7 3.3 8.4 6.1 0.1 3.7 3 1 2 5 5 5 0 TUP1-like enhancer of split S-l_SbsC_C PF18316.1 KXZ51001.1 - 0.39 11.3 4.4 35 5.0 0.1 3.5 4 0 0 4 4 4 0 S-layer protein SbsC C-terminal domain Thioredoxin PF00085.20 KXZ51002.1 - 3.3e-13 49.5 0.0 4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KXZ51002.1 - 0.0024 17.8 0.0 0.0057 16.6 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KXZ51002.1 - 0.0027 17.4 0.0 0.0031 17.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KXZ51002.1 - 0.016 15.6 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like G3P_acyltransf PF02660.15 KXZ51002.1 - 0.063 13.3 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase Thioredoxin_9 PF14595.6 KXZ51002.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Myb_DNA-binding PF00249.31 KXZ51003.1 - 1.4e-28 98.8 2.1 7.4e-16 58.1 0.2 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ51003.1 - 4.2e-16 58.9 0.0 6.2e-12 45.6 0.0 3.4 2 2 2 4 4 4 2 Myb-like DNA-binding domain SlyX PF04102.12 KXZ51003.1 - 0.023 15.3 0.1 0.023 15.3 0.1 7.1 7 2 3 10 10 10 0 SlyX DUF1664 PF07889.12 KXZ51003.1 - 0.12 12.4 2.8 0.28 11.3 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF2046 PF09755.9 KXZ51003.1 - 6.9 5.8 10.7 0.087 12.0 1.8 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Med9 PF07544.13 KXZ51003.1 - 8.1 6.6 6.9 15 5.7 0.0 3.8 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 CRISPR_Cas6 PF10040.9 KXZ51006.1 - 0.096 13.3 0.3 0.13 12.9 0.3 1.3 1 0 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 DUF1499 PF07386.11 KXZ51007.1 - 9.5e-06 26.2 0.0 1.4e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) LRR_8 PF13855.6 KXZ51008.1 - 1.7e-14 53.3 13.2 0.00015 21.5 0.1 5.3 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KXZ51008.1 - 5.9e-11 42.4 12.6 0.17 12.3 0.0 6.1 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ51008.1 - 1e-05 25.4 3.0 14 6.7 0.5 7.1 8 0 0 8 8 8 1 Leucine Rich Repeat Guanylate_cyc PF00211.20 KXZ51008.1 - 1.1e-05 25.1 0.0 0.078 12.6 0.0 3.4 3 1 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain LRR_6 PF13516.6 KXZ51008.1 - 0.0028 17.6 6.9 49 4.3 0.2 6.6 7 0 0 7 7 7 0 Leucine Rich repeat RINGv PF12906.7 KXZ51012.1 - 6.4e-09 35.8 8.4 1.2e-08 34.9 8.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXZ51012.1 - 0.0017 18.7 7.8 0.0041 17.4 7.8 1.7 1 0 0 1 1 1 1 Ring finger domain HSP33 PF01430.19 KXZ51013.1 - 1.1e-63 215.1 0.0 1.3e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein GLTSCR1 PF15249.6 KXZ51014.1 - 2.3e-16 60.1 1.9 6.1e-16 58.7 1.9 1.7 1 1 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Biotin_lipoyl PF00364.22 KXZ51015.1 - 1.4e-21 76.1 1.9 2.8e-21 75.1 1.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXZ51015.1 - 1.4e-06 28.0 0.4 0.0045 16.8 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 KXZ51015.1 - 0.00046 20.1 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein PYNP_C PF07831.13 KXZ51015.1 - 0.0059 16.2 1.2 1 9.1 0.1 2.4 1 1 1 2 2 2 2 Pyrimidine nucleoside phosphorylase C-terminal domain RnfC_N PF13375.6 KXZ51015.1 - 0.013 15.4 2.6 0.084 12.8 0.1 2.6 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 KXZ51015.1 - 0.046 13.5 1.4 9.2 6.0 0.0 3.2 2 2 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DEC-1_N PF04625.13 KXZ51015.1 - 0.071 12.1 12.8 0.094 11.7 12.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peptidase_M23 PF01551.22 KXZ51015.1 - 0.15 12.3 0.8 30 4.9 0.2 3.1 2 1 1 3 3 3 0 Peptidase family M23 CDC48_2 PF02933.17 KXZ51015.1 - 0.91 9.4 5.8 15 5.5 0.2 3.5 3 1 1 4 4 4 0 Cell division protein 48 (CDC48), domain 2 FAP PF07174.11 KXZ51015.1 - 6.5 6.1 20.7 9.9 5.5 20.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PKD_channel PF08016.12 KXZ51016.1 - 1e-28 100.2 15.2 2.8e-24 85.6 6.1 2.3 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 KXZ51016.1 - 3.2e-12 46.2 13.9 6.3e-12 45.2 13.9 1.4 1 0 0 1 1 1 1 Ion transport protein KxDL PF10241.9 KXZ51016.1 - 8.9 6.7 15.7 2.5 8.4 1.5 3.8 3 0 0 3 3 3 0 Uncharacterized conserved protein Gpr1_Fun34_YaaH PF01184.19 KXZ51017.1 - 6.3e-30 104.3 20.7 7.9e-30 104.0 20.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pkinase PF00069.25 KXZ51018.1 - 2e-57 194.6 0.0 3.1e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51018.1 - 1.7e-32 112.7 0.0 2.4e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ51018.1 - 1.5e-10 40.9 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ51018.1 - 7.3e-09 34.9 0.0 1.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF5585 PF17823.1 KXZ51018.1 - 0.21 10.5 17.8 0.3 10.0 17.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) FMO-like PF00743.19 KXZ51019.1 - 3.7e-28 98.2 0.0 3.5e-16 58.7 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXZ51019.1 - 3.9e-09 36.2 0.0 1.7e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ51019.1 - 3.1e-06 26.6 0.0 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ51019.1 - 0.0048 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ51019.1 - 0.021 14.0 0.0 0.066 12.3 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase PF00069.25 KXZ51020.1 - 2.1e-53 181.4 0.0 2.8e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51020.1 - 2.7e-35 121.9 0.0 4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ51020.1 - 0.038 12.8 0.0 0.071 11.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXZ51020.1 - 0.059 12.3 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PPPI_inhib PF14895.6 KXZ51021.1 - 0.16 11.1 1.4 0.27 10.4 0.1 2.0 2 1 0 2 2 2 0 Protein phosphatase 1 inhibitor Glyco_transf_92 PF01697.27 KXZ51022.1 - 1.5e-08 34.6 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KXZ51022.1 - 0.0064 17.0 0.1 0.013 16.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF2607 PF10795.9 KXZ51022.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) F5_F8_type_C PF00754.25 KXZ51023.1 - 4.3e-18 65.7 0.0 0.21 11.7 0.0 10.2 10 0 0 10 10 10 7 F5/8 type C domain FBPase PF00316.20 KXZ51024.1 - 2.2e-25 89.2 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DUF3707 PF12499.8 KXZ51026.1 - 0.0038 17.8 0.2 0.007 16.9 0.2 1.4 1 0 0 1 1 1 1 Pherophorin Lectin_C PF00059.21 KXZ51026.1 - 0.025 15.3 0.0 0.043 14.5 0.0 1.6 1 1 0 1 1 1 0 Lectin C-type domain DUF3707 PF12499.8 KXZ51027.1 - 2.8e-23 83.1 6.2 3.4e-23 82.8 6.2 1.1 1 0 0 1 1 1 1 Pherophorin CLIP_SPH_mas PF18398.1 KXZ51027.1 - 0.026 14.9 0.9 0.026 14.9 0.9 2.0 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade Aldo_ket_red PF00248.21 KXZ51028.1 - 2.7e-74 250.0 0.0 3.1e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_AsnC-type PF13404.6 KXZ51028.1 - 0.032 14.1 0.2 0.095 12.6 0.2 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain FMO-like PF00743.19 KXZ51030.1 - 1.5e-38 132.6 0.0 1.6e-24 86.3 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXZ51030.1 - 3.2e-18 66.0 0.0 1.5e-17 63.8 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ51030.1 - 1.5e-15 57.2 0.0 2.8e-13 49.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXZ51030.1 - 8e-10 38.8 0.7 9.3e-09 35.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ51030.1 - 1.5e-07 31.4 0.4 2.9e-05 23.8 1.1 2.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXZ51030.1 - 1.6e-07 30.8 0.0 1.2e-06 28.0 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXZ51030.1 - 5.8e-07 30.0 0.2 0.01 16.4 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXZ51030.1 - 7.4e-07 28.8 0.0 0.00021 20.7 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KXZ51030.1 - 2.2e-05 23.8 1.7 6.7e-05 22.3 0.2 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXZ51030.1 - 6.6e-05 22.2 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXZ51030.1 - 0.00014 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXZ51030.1 - 0.00016 20.8 0.2 0.00099 18.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXZ51030.1 - 0.00019 21.8 0.1 1 9.9 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 KXZ51030.1 - 0.00023 20.5 0.9 0.0012 18.2 0.2 2.0 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 KXZ51030.1 - 0.00045 20.3 0.3 0.67 10.0 0.0 2.2 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KXZ51030.1 - 0.00061 19.0 0.3 0.0021 17.2 0.5 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXZ51030.1 - 0.00078 19.5 0.4 1.6 8.7 0.2 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXZ51030.1 - 0.00079 18.8 0.8 0.0045 16.3 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KXZ51030.1 - 0.0032 16.2 0.3 0.0032 16.2 0.3 1.5 2 0 0 2 2 2 1 HI0933-like protein Mem_trans PF03547.18 KXZ51031.1 - 6.9e-14 51.0 0.5 6.2e-11 41.3 0.6 2.3 2 0 0 2 2 2 2 Membrane transport protein Pkinase_Tyr PF07714.17 KXZ51035.1 - 1.8e-05 24.2 0.0 0.00012 21.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ51035.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.4 2 0 0 2 2 2 0 Protein kinase domain Ank_4 PF13637.6 KXZ51036.1 - 1.3e-05 25.6 0.3 1 10.0 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51036.1 - 9e-05 23.0 0.1 0.0052 17.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ51036.1 - 0.0013 19.0 0.2 34 5.5 0.0 4.7 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KXZ51036.1 - 0.041 14.2 1.6 1.1e+02 3.3 0.1 4.4 3 2 2 5 5 5 0 Ankyrin repeats (many copies) IstB_IS21 PF01695.17 KXZ51037.1 - 0.069 12.9 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KXZ51037.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NTPase TTL PF03133.15 KXZ51038.1 - 2.2e-89 299.5 0.0 2.9e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ51038.1 - 1.2e-06 28.0 0.0 0.00024 20.4 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ51038.1 - 0.00049 19.4 0.0 0.0044 16.3 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 KXZ51038.1 - 0.19 11.3 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF4169 PF13770.6 KXZ51038.1 - 0.55 10.5 4.1 1.1 9.6 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) ATP-sulfurylase PF01747.17 KXZ51040.1 - 7.5e-68 228.2 0.2 1.1e-67 227.6 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KXZ51040.1 - 2.3e-35 121.6 0.0 3.2e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain SDA1 PF05285.12 KXZ51041.1 - 0.18 11.2 17.4 0.19 11.1 5.3 2.2 2 0 0 2 2 2 0 SDA1 Cwf_Cwc_15 PF04889.12 KXZ51041.1 - 2.3 7.9 25.3 0.73 9.5 7.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.18 KXZ51041.1 - 4.2 7.2 8.7 5.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Myc amino-terminal region CDC27 PF09507.10 KXZ51041.1 - 6.7 6.0 20.3 0.073 12.5 4.8 2.1 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 Ppx-GppA PF02541.16 KXZ51042.1 - 0.056 12.9 1.8 0.087 12.2 1.7 1.3 1 1 0 1 1 1 0 Ppx/GppA phosphatase family Acyl_transf_3 PF01757.22 KXZ51042.1 - 0.071 12.2 0.8 0.079 12.0 0.8 1.1 1 0 0 1 1 1 0 Acyltransferase family ERCC3_RAD25_C PF16203.5 KXZ51043.1 - 5e-114 379.6 0.0 8.3e-114 378.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KXZ51043.1 - 4.6e-26 91.4 0.2 8.7e-26 90.6 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ51043.1 - 3.9e-14 53.0 0.0 7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXZ51043.1 - 3.3e-10 40.3 0.1 9.7e-10 38.8 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 KXZ51043.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase APG5 PF04106.12 KXZ51043.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 ThiF PF00899.21 KXZ51045.1 - 7.8e-72 241.5 0.1 1.1e-71 241.0 0.1 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KXZ51045.1 - 8.4e-17 61.5 0.0 1.6e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KXZ51045.1 - 9.5e-14 51.9 0.0 1.3e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KXZ51045.1 - 0.0038 17.6 0.0 0.017 15.6 0.0 2.1 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXZ51045.1 - 0.022 14.8 0.1 0.044 13.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PHO4 PF01384.20 KXZ51046.1 - 5.1e-98 328.2 23.2 6.5e-98 327.9 23.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family TMEM18 PF14770.6 KXZ51046.1 - 0.039 13.9 1.6 0.11 12.5 1.6 1.7 1 0 0 1 1 1 0 Transmembrane protein 18 OAD_gamma PF04277.13 KXZ51046.1 - 2.2 9.0 8.2 0.4 11.3 0.3 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Glyco_hydro_47 PF01532.20 KXZ51047.1 - 6.9e-73 246.1 0.0 1.3e-60 205.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 PA PF02225.22 KXZ51047.1 - 1.8e-08 34.3 0.1 1.8e-08 34.3 0.1 3.2 3 0 0 3 3 3 1 PA domain Met_gamma_lyase PF06838.11 KXZ51048.1 - 1.7e-159 530.8 0.0 1.9e-159 530.6 0.0 1.0 1 0 0 1 1 1 1 Methionine gamma-lyase Cys_Met_Meta_PP PF01053.20 KXZ51048.1 - 1.8e-06 26.8 0.1 7.9e-06 24.6 0.1 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXZ51048.1 - 0.23 10.6 0.0 0.44 9.6 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II Hyd_WA PF06462.12 KXZ51048.1 - 0.34 11.0 2.8 2.2 8.4 0.1 3.1 2 0 0 2 2 2 0 Propeller Pkinase PF00069.25 KXZ51049.1 - 7.3e-29 100.9 0.1 9.2e-27 94.0 0.1 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51049.1 - 5.9e-22 78.2 0.1 2.8e-21 76.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KXZ51049.1 - 1e-05 25.6 0.0 0.00024 21.3 0.0 2.4 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C-terminal domain ArfGap PF01412.18 KXZ51050.1 - 2e-19 69.8 0.0 4.1e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf LRR_8 PF13855.6 KXZ51051.1 - 0.004 16.9 11.8 6.3 6.6 0.2 6.8 5 1 2 7 7 7 2 Leucine rich repeat LRR_4 PF12799.7 KXZ51051.1 - 0.026 14.9 17.7 9.4 6.8 0.2 6.9 7 1 2 9 9 9 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ51051.1 - 0.036 14.1 22.4 1.7 8.9 0.0 7.2 9 0 0 9 9 9 0 Leucine Rich repeat Presenilin PF01080.17 KXZ51051.1 - 0.49 9.1 8.8 0.74 8.5 8.8 1.3 1 0 0 1 1 1 0 Presenilin Spore_YtfJ PF09579.10 KXZ51051.1 - 1.3 9.2 3.1 3.2 8.0 3.1 1.6 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) ATG16 PF08614.11 KXZ51052.1 - 0.0022 18.2 13.2 0.0022 18.2 13.2 11.9 2 1 9 12 12 12 5 Autophagy protein 16 (ATG16) Thiamine_BP PF01910.17 KXZ51052.1 - 0.44 10.5 4.7 1 9.4 0.1 3.6 4 0 0 4 4 4 0 Thiamine-binding protein Ion_trans_2 PF07885.16 KXZ51053.1 - 2.8e-10 40.0 2.6 2.8e-10 40.0 2.6 2.3 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KXZ51053.1 - 6.1e-10 38.7 14.4 1e-09 38.0 14.4 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KXZ51053.1 - 1.7e-09 37.6 0.0 4.7e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain SCAMP PF04144.13 KXZ51053.1 - 7.5 6.8 14.6 0.2 11.9 6.5 2.2 2 1 0 2 2 2 0 SCAMP family TFIIA PF03153.13 KXZ51055.1 - 3.6e-05 23.9 51.7 3.6e-05 23.9 51.7 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 KXZ51055.1 - 0.019 15.2 13.3 0.032 14.4 13.3 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 KXZ51055.1 - 0.39 10.5 25.2 0.74 9.6 25.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Miga PF10265.9 KXZ51055.1 - 1.6 7.6 13.3 2.5 6.9 13.3 1.3 1 0 0 1 1 1 0 Mitoguardin Exonuc_VII_L PF02601.15 KXZ51055.1 - 2.1 7.8 26.9 4.6 6.7 26.9 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit eIF-3_zeta PF05091.12 KXZ51055.1 - 2.3 7.1 29.8 4.3 6.2 29.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 KXZ51055.1 - 5.2 6.8 19.2 11 5.7 19.2 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hamartin PF04388.12 KXZ51055.1 - 5.3 5.6 24.4 0.56 8.8 18.2 1.9 2 0 0 2 2 2 0 Hamartin protein LAP1C PF05609.12 KXZ51055.1 - 6.3 5.8 25.6 13 4.7 25.6 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PA26 PF04636.13 KXZ51055.1 - 7.9 5.3 19.5 12 4.7 19.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4471 PF14740.6 KXZ51055.1 - 8 5.6 17.7 12 5.1 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) CDC45 PF02724.14 KXZ51055.1 - 8.8 4.5 24.5 16 3.7 24.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Aa_trans PF01490.18 KXZ51057.1 - 2.5e-14 52.8 9.5 2.7e-14 52.7 9.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4442 PF14539.6 KXZ51057.1 - 0.053 13.7 0.2 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) MitoNEET_N PF10660.9 KXZ51057.1 - 0.19 11.8 4.7 2.9 8.0 1.9 2.7 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Ank PF00023.30 KXZ51058.1 - 1.7e-06 28.2 0.1 7.6e-06 26.1 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXZ51058.1 - 6.1e-05 23.1 0.0 0.00025 21.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXZ51058.1 - 8.5e-05 22.8 0.1 0.0002 21.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51058.1 - 0.0089 16.6 0.0 0.023 15.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TrbC PF04956.13 KXZ51058.1 - 0.022 15.0 0.1 8.8 6.6 0.0 2.9 2 0 0 2 2 2 0 TrbC/VIRB2 family Ank_4 PF13637.6 KXZ51058.1 - 0.17 12.5 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) EPL1 PF10513.9 KXZ51058.1 - 0.37 11.2 17.4 5.8 7.3 11.7 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like DDHD PF02862.17 KXZ51058.1 - 0.4 10.8 9.3 5.9 7.0 7.3 2.3 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 KXZ51058.1 - 2.3 8.2 10.1 32 4.5 7.9 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.16 KXZ51059.1 - 6.2e-25 87.9 41.7 6.2e-25 87.9 41.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXZ51059.1 - 1.3e-13 50.1 19.6 5.8e-06 24.9 0.6 3.9 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXZ51059.1 - 0.3 9.9 24.6 2.7 6.7 24.6 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter PTR2 PF00854.21 KXZ51059.1 - 4.4 6.0 7.4 1.1 8.0 3.6 1.8 1 1 1 2 2 2 0 POT family MCM PF00493.23 KXZ51060.1 - 2.4e-95 317.9 0.0 3.6e-95 317.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXZ51060.1 - 3.1e-29 101.4 0.0 5.4e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXZ51060.1 - 1.7e-14 54.0 0.3 1.1e-13 51.5 0.3 2.3 1 1 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KXZ51060.1 - 2.2e-09 37.0 0.2 1.3e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KXZ51060.1 - 1.9e-06 28.4 0.0 4.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 KXZ51060.1 - 6.9e-05 22.7 0.1 0.00097 19.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ51060.1 - 0.00073 19.5 0.0 0.0039 17.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXZ51060.1 - 0.0029 17.3 0.2 0.024 14.3 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 KXZ51060.1 - 0.012 16.1 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FMO-like PF00743.19 KXZ51062.1 - 3.3e-33 114.9 0.0 1.6e-19 69.8 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXZ51062.1 - 9.7e-12 44.7 0.0 2.5e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ51062.1 - 1.8e-08 33.9 0.1 3.7e-08 32.9 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXZ51062.1 - 4.7e-08 32.6 0.0 4.8e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ51062.1 - 0.076 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-MYND PF01753.18 KXZ51063.1 - 2e-12 47.0 7.8 3.8e-12 46.1 7.8 1.5 1 0 0 1 1 1 1 MYND finger RBFA PF02033.18 KXZ51064.1 - 1.7e-18 67.0 0.0 2.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome-binding factor A CDC45 PF02724.14 KXZ51064.1 - 0.55 8.5 4.0 0.58 8.4 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CS PF04969.16 KXZ51067.1 - 0.23 12.5 0.0 0.37 11.8 0.0 1.4 1 0 0 1 1 1 0 CS domain Glucan_synthase PF02364.15 KXZ51068.1 - 1.2e-121 407.4 0.0 4.3e-104 349.4 0.9 3.3 2 2 0 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KXZ51068.1 - 1.1e-10 42.0 0.0 9.4e-06 26.0 0.2 2.4 2 0 0 2 2 2 2 1,3-beta-glucan synthase subunit FKS1, domain-1 3-alpha PF03475.14 KXZ51068.1 - 0.033 14.0 2.4 0.25 11.2 0.2 3.1 2 0 0 2 2 2 0 3-alpha domain SpoVS PF04232.12 KXZ51069.1 - 4e-18 64.9 3.1 1.5e-10 40.7 0.2 4.5 4 0 0 4 4 4 3 Stage V sporulation protein S (SpoVS) Pertus-S4-tox PF09275.10 KXZ51069.1 - 0.033 14.5 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 Pertussis toxin S4 subunit ATG16 PF08614.11 KXZ51070.1 - 0.00016 22.0 51.4 0.00019 21.7 12.4 3.3 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KXZ51070.1 - 0.029 14.6 1.4 0.029 14.6 1.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 KXZ51070.1 - 0.21 10.2 26.7 0.33 9.5 15.2 2.1 1 1 1 2 2 2 0 AAA domain ADIP PF11559.8 KXZ51070.1 - 0.54 10.3 37.5 1.4 9.0 6.9 3.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.6 KXZ51070.1 - 1.8 8.5 41.0 0.026 14.6 16.1 3.2 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 KXZ51070.1 - 2.6 8.1 42.7 0.077 13.0 8.9 4.5 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 KXZ51070.1 - 2.7 7.9 17.3 3.8 7.5 3.0 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Filament PF00038.21 KXZ51070.1 - 3.3 7.2 41.4 0.3 10.6 28.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein GAS PF13851.6 KXZ51070.1 - 3.6 6.9 41.4 0.32 10.3 3.5 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding IFT46_B_C PF12317.8 KXZ51070.1 - 5.2 6.7 6.7 3.4 7.3 0.6 2.5 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Tropomyosin_1 PF12718.7 KXZ51070.1 - 6.7 6.9 43.2 0.39 10.9 9.3 4.7 1 1 3 4 4 2 0 Tropomyosin like Pkinase_Tyr PF07714.17 KXZ51071.1 - 3.4e-40 138.0 0.0 4.7e-18 65.4 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ51071.1 - 1.1e-33 116.7 0.0 4.4e-26 91.8 0.0 3.8 3 1 0 3 3 3 2 Protein kinase domain APH PF01636.23 KXZ51071.1 - 0.02 14.8 0.3 0.047 13.6 0.3 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M11 PF05548.11 KXZ51072.1 - 4.2e-44 151.0 2.2 5.4e-27 94.8 0.2 2.2 2 0 0 2 2 2 2 Gametolysin peptidase M11 Peptidase_M7 PF02031.16 KXZ51072.1 - 0.0015 18.6 0.7 1.1 9.4 0.1 4.3 4 0 0 4 4 4 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_3 PF13582.6 KXZ51072.1 - 0.0047 17.4 0.1 0.014 15.9 0.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KXZ51072.1 - 0.023 13.7 0.1 0.042 12.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 KXZ51072.1 - 0.024 14.8 0.1 0.076 13.1 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXZ51072.1 - 0.044 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M11 PF05548.11 KXZ51073.1 - 2.4e-05 23.7 0.3 3.3e-05 23.2 0.3 1.3 1 1 0 1 1 1 1 Gametolysin peptidase M11 GHMP_kinases_N PF00288.26 KXZ51075.1 - 9.2e-08 32.2 0.3 5.7e-07 29.7 0.2 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXZ51075.1 - 0.00029 21.1 0.0 0.00067 20.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal S-methyl_trans PF02574.16 KXZ51076.1 - 5.3 6.8 7.0 0.13 12.0 0.7 1.6 2 0 0 2 2 2 0 Homocysteine S-methyltransferase Csm1_N PF18504.1 KXZ51076.1 - 6.4 7.2 7.3 9.3 6.7 0.3 3.3 3 1 0 3 3 3 0 Csm1 N-terminal domain SET PF00856.28 KXZ51077.1 - 7.5e-07 29.7 0.0 1.3e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KXZ51077.1 - 0.00047 20.2 5.4 0.00047 20.2 5.4 2.9 3 0 0 3 3 3 1 MYND finger AMP-binding PF00501.28 KXZ51078.1 - 3.4e-84 282.9 0.0 5e-84 282.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme SOUL PF04832.12 KXZ51079.1 - 2.8e-46 157.7 0.0 3.3e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein Band_7 PF01145.25 KXZ51080.1 - 1e-17 64.7 5.7 3.8e-17 62.9 5.7 1.9 1 1 0 1 1 1 1 SPFH domain / Band 7 family CLP_protease PF00574.23 KXZ51081.1 - 3.3e-54 183.6 1.1 4.6e-54 183.1 1.1 1.2 1 0 0 1 1 1 1 Clp protease Zip PF02535.22 KXZ51082.1 - 4.2e-39 134.7 9.8 6.3e-39 134.1 9.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF21 PF01595.20 KXZ51082.1 - 0.018 14.7 0.2 0.12 12.0 0.3 2.3 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain DUF3584 PF12128.8 KXZ51083.1 - 0.0089 13.6 20.7 0.0098 13.5 20.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Nbl1_Borealin_N PF10444.9 KXZ51083.1 - 0.052 13.2 0.3 0.052 13.2 0.3 3.6 1 1 2 3 3 3 0 Nbl1 / Borealin N terminal DUF948 PF06103.11 KXZ51083.1 - 0.097 12.9 4.5 0.61 10.4 1.4 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 KXZ51083.1 - 0.11 12.0 12.2 0.14 11.7 12.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 KXZ51083.1 - 0.31 11.2 11.7 0.18 12.0 6.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.24 KXZ51083.1 - 0.41 10.6 8.9 0.13 12.2 4.1 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD HeLo PF14479.6 KXZ51083.1 - 0.45 10.3 8.7 0.19 11.5 6.2 1.6 1 1 1 2 2 2 0 Prion-inhibition and propagation ApoO PF09769.9 KXZ51083.1 - 0.61 10.1 4.5 7.6 6.5 4.5 2.2 1 1 0 1 1 1 0 Apolipoprotein O Phage_Mu_Gam PF07352.12 KXZ51083.1 - 0.66 9.9 19.6 0.05 13.5 6.9 2.9 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein FAM184 PF15665.5 KXZ51083.1 - 0.73 9.6 21.8 1.8 8.3 21.9 1.5 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B RRF PF01765.19 KXZ51083.1 - 0.93 9.4 16.0 0.18 11.8 7.2 2.4 1 1 1 2 2 2 0 Ribosome recycling factor CREPT PF16566.5 KXZ51083.1 - 0.98 9.6 16.8 0.7 10.0 9.5 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 KXZ51083.1 - 1.2 9.2 6.2 1.8 8.6 0.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KXZ51083.1 - 1.7 6.5 7.3 2 6.3 7.3 1.1 1 0 0 1 1 1 0 Prominin TraW_N PF12477.8 KXZ51083.1 - 2.3 8.3 4.9 1.2 9.2 1.7 2.2 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Syntaxin PF00804.25 KXZ51083.1 - 2.7 7.6 17.4 0.037 13.7 7.1 2.0 1 1 1 2 2 2 0 Syntaxin YqhG PF11079.8 KXZ51083.1 - 3 6.7 8.1 1.7 7.5 5.3 1.8 1 1 1 2 2 2 0 Bacterial protein YqhG of unknown function V-SNARE PF05008.15 KXZ51083.1 - 3.5 8.1 16.4 0.18 12.2 7.6 2.7 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus V_ATPase_I PF01496.19 KXZ51083.1 - 3.8 5.3 11.8 4.5 5.1 11.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnn_1N PF07989.11 KXZ51083.1 - 5.1 7.3 10.7 5 7.4 5.7 2.9 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 FAM76 PF16046.5 KXZ51083.1 - 5.3 6.3 12.7 1.4 8.2 9.4 1.5 1 1 0 1 1 1 0 FAM76 protein COG2 PF06148.11 KXZ51083.1 - 7.9 6.6 11.2 0.99 9.5 3.1 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.13 KXZ51083.1 - 8.8 7.0 23.1 0.24 12.0 5.4 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 KXZ51083.1 - 9.7 5.4 24.0 18 4.6 23.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ARD PF03079.14 KXZ51083.1 - 9.8 6.3 7.0 42 4.3 0.1 2.1 1 1 1 2 2 2 0 ARD/ARD' family BAR PF03114.18 KXZ51084.1 - 0.00031 20.5 0.1 0.00051 19.8 0.1 1.2 1 0 0 1 1 1 1 BAR domain OCRE PF17780.1 KXZ51085.1 - 4.5e-10 39.4 5.3 8.9e-10 38.5 5.3 1.4 1 0 0 1 1 1 1 OCRE domain PRP3 PF08572.10 KXZ51085.1 - 0.066 12.9 0.3 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) NUDE_C PF04880.13 KXZ51085.1 - 6.8 7.1 6.9 1.3 9.5 1.6 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Q_salvage PF10343.9 KXZ51087.1 - 5.8e-20 72.0 0.0 8.4e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Ribosomal_L21p PF00829.21 KXZ51088.1 - 4.8e-34 116.6 0.3 8.5e-34 115.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FtsK_alpha PF17854.1 KXZ51088.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK alpha domain DAGAT PF03982.13 KXZ51089.1 - 2e-27 95.9 0.6 2.8e-26 92.1 0.6 2.0 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Tweety PF04906.13 KXZ51090.1 - 3.1e-05 22.8 3.8 7e-05 21.7 0.1 2.3 2 0 0 2 2 2 1 Tweety DUF948 PF06103.11 KXZ51090.1 - 0.00017 21.8 1.8 2.7 8.3 0.0 4.9 4 1 0 4 4 4 2 Bacterial protein of unknown function (DUF948) DUF2207 PF09972.9 KXZ51090.1 - 0.01 14.6 0.9 0.35 9.6 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Prominin PF05478.11 KXZ51090.1 - 0.019 12.9 3.6 0.022 12.8 0.0 2.1 2 0 0 2 2 2 0 Prominin ApoLp-III PF07464.11 KXZ51090.1 - 0.16 12.0 1.2 2 8.5 0.4 2.8 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF3270 PF11674.8 KXZ51090.1 - 0.77 10.0 5.9 0.12 12.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) WD40 PF00400.32 KXZ51092.1 - 1.2e-05 26.0 0.0 0.32 11.9 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat SUI1 PF01253.22 KXZ51093.1 - 3.2e-26 91.7 0.9 4.1e-26 91.3 0.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 W2 PF02020.18 KXZ51094.1 - 2.2e-21 75.8 0.7 5.3e-21 74.5 0.7 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon PPR_2 PF13041.6 KXZ51095.1 - 7.3e-29 99.7 0.0 5.5e-06 26.5 0.0 7.2 5 1 3 8 8 8 5 PPR repeat family PPR_3 PF13812.6 KXZ51095.1 - 9.1e-27 92.9 0.0 8.8e-08 32.1 0.0 5.7 4 1 0 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 KXZ51095.1 - 9.4e-25 85.1 4.2 0.0065 16.6 0.0 9.1 10 0 0 10 10 10 5 PPR repeat PPR_long PF17177.4 KXZ51095.1 - 1.9e-16 60.0 5.7 5e-07 29.3 0.1 4.1 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KXZ51095.1 - 1.4e-09 37.5 4.0 0.044 13.5 0.1 5.7 5 0 0 5 5 5 3 PPR repeat UTP15_C PF09384.10 KXZ51095.1 - 0.098 12.3 0.3 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 UTP15 C terminal Gcd10p PF04189.13 KXZ51095.1 - 0.29 10.2 0.0 0.56 9.3 0.0 1.3 1 0 0 1 1 1 0 Gcd10p family HIF-1a_CTAD PF08778.10 KXZ51096.1 - 0.067 12.8 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Erv26 PF04148.13 KXZ51097.1 - 3.7e-17 62.8 4.5 1.2e-14 54.6 4.5 2.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 PI3_PI4_kinase PF00454.27 KXZ51100.1 - 0.00046 20.1 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Filament_head PF04732.14 KXZ51100.1 - 4.5 8.2 8.9 2 9.3 0.1 3.0 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region DUF1180 PF06679.12 KXZ51101.1 - 5.6 7.4 5.4 0.58 10.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) GTP_EFTU PF00009.27 KXZ51102.1 - 4.2e-51 173.3 0.0 6.7e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXZ51102.1 - 4.1e-18 65.2 0.0 8.4e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXZ51102.1 - 1.1e-13 51.3 1.3 3.2e-13 49.9 0.3 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ51102.1 - 3.2e-08 33.6 0.2 7.9e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KXZ51102.1 - 6.3e-06 26.2 0.0 8.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II Septin PF00735.18 KXZ51102.1 - 0.0013 18.1 0.1 0.0021 17.4 0.1 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 KXZ51102.1 - 0.0065 16.5 0.0 2.9 7.9 0.0 2.3 1 1 0 2 2 2 2 Dynamin family FeoB_N PF02421.18 KXZ51102.1 - 0.011 15.3 0.2 0.16 11.5 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KXZ51102.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ51102.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Fer2 PF00111.27 KXZ51103.1 - 5.1e-15 55.2 0.1 7.6e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 KXZ51103.1 - 0.00077 19.5 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ketoacyl-synt PF00109.26 KXZ51105.1 - 5.7e-51 173.5 0.5 5.7e-51 173.5 0.5 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXZ51105.1 - 2e-34 118.1 1.5 3.6e-34 117.3 1.5 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXZ51105.1 - 0.023 14.1 0.2 0.052 12.9 0.2 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain UL73_N PF12522.8 KXZ51106.1 - 0.36 10.6 1.1 0.57 10.0 1.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Pkinase PF00069.25 KXZ51107.1 - 8.8e-41 140.0 0.0 2.4e-40 138.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51107.1 - 7.3e-37 127.0 0.0 3e-36 125.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXZ51107.1 - 0.024 14.6 1.1 0.036 14.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ51107.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase AsmA_2 PF13502.6 KXZ51108.1 - 0.03 13.8 1.3 0.063 12.8 0.4 2.0 2 2 0 2 2 2 0 AsmA-like C-terminal region MutS_III PF05192.18 KXZ51109.1 - 1.2e-27 97.3 0.0 1.8e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.21 KXZ51109.1 - 6.5e-21 75.2 0.4 5.5e-15 55.9 0.1 2.3 2 0 0 2 2 2 2 MutS domain V AAA_27 PF13514.6 KXZ51109.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MutS_IV PF05190.18 KXZ51109.1 - 0.27 11.6 0.0 2.3 8.6 0.0 2.1 2 0 0 2 2 2 0 MutS family domain IV Glyco_transf_49 PF13896.6 KXZ51110.1 - 1.7e-22 80.2 0.2 5e-18 65.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_90 PF05686.12 KXZ51111.1 - 1.1e-15 57.5 0.1 2.1e-15 56.5 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 TerC PF03741.16 KXZ51113.1 - 2.1e-46 157.9 9.2 3.4e-46 157.2 9.2 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family CCB2_CCB4 PF11152.8 KXZ51113.1 - 0.051 12.9 0.7 0.082 12.2 0.7 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 zf-C2H2_2 PF12756.7 KXZ51114.1 - 6.4e-16 58.5 0.0 1.9e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Thymidylat_synt PF00303.19 KXZ51115.1 - 5.2e-111 370.1 0.0 6.4e-111 369.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 KXZ51115.1 - 4.9e-25 88.1 0.0 1.8e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrofolate reductase CRAL_TRIO PF00650.20 KXZ51116.1 - 7e-32 110.3 0.0 2.4e-31 108.6 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXZ51116.1 - 4.8e-07 29.9 0.9 1.6e-06 28.2 0.9 1.9 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXZ51116.1 - 0.032 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain TPT PF03151.16 KXZ51117.1 - 1.5e-14 54.0 15.2 2.2e-14 53.5 15.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Asp_protease_2 PF13650.6 KXZ51118.1 - 1.8e-11 44.5 0.5 8.2e-10 39.2 0.1 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KXZ51118.1 - 3.2e-08 34.0 0.1 2.7e-07 31.0 0.0 2.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease DUF3707 PF12499.8 KXZ51119.1 - 1.4e-45 155.4 17.6 1.6e-17 64.4 7.3 4.3 4 0 0 4 4 4 4 Pherophorin DUF3707 PF12499.8 KXZ51120.1 - 1.5e-59 200.6 14.9 2.7e-34 118.8 2.3 2.5 2 0 0 2 2 2 2 Pherophorin DUF3707 PF12499.8 KXZ51121.1 - 5.9e-66 221.4 15.8 6.1e-37 127.3 6.2 2.2 2 0 0 2 2 2 2 Pherophorin Pkinase PF00069.25 KXZ51123.1 - 6e-23 81.5 0.1 4.7e-20 72.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51123.1 - 4.2e-08 32.8 0.0 1.1e-07 31.4 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ51123.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RNA_pol_Rpb4 PF03874.16 KXZ51124.1 - 9.2e-13 48.6 0.0 1.2e-12 48.2 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 PSK_trans_fac PF07704.11 KXZ51124.1 - 0.063 14.0 0.8 0.11 13.3 0.8 1.4 1 0 0 1 1 1 0 Rv0623-like transcription factor Ank_4 PF13637.6 KXZ51125.1 - 2.2e-09 37.6 3.2 1.6 9.4 0.0 6.4 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51125.1 - 0.00019 22.0 0.5 8.8 7.0 0.0 4.6 1 1 4 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ51125.1 - 0.0003 21.0 5.5 1.1e+02 3.8 0.0 7.7 8 0 0 8 8 8 0 Ankyrin repeat DUF3742 PF12553.8 KXZ51125.1 - 0.0077 16.3 4.5 0.77 9.9 0.2 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3742) PHY PF00360.20 KXZ51125.1 - 0.078 12.3 0.1 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Phytochrome region DUF4272 PF14094.6 KXZ51125.1 - 2.9 7.1 6.6 1.4 8.1 4.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) Ank_3 PF13606.6 KXZ51126.1 - 4.7e-05 23.5 0.3 85 4.2 0.0 6.7 8 0 0 8 8 8 0 Ankyrin repeat Ank_2 PF12796.7 KXZ51126.1 - 0.00056 20.5 0.0 0.1 13.2 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51126.1 - 0.0014 19.2 0.1 20 5.9 0.0 5.5 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ51127.1 - 1.6e-07 31.7 1.6 0.32 11.6 0.0 7.5 8 1 0 8 8 8 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51127.1 - 3.4e-05 24.4 0.0 1.6 9.4 0.0 5.1 3 2 3 6 6 6 2 Ankyrin repeats (3 copies) Pkinase PF00069.25 KXZ51128.1 - 1.6e-11 44.1 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51128.1 - 5e-10 39.1 0.0 7.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KXZ51129.1 - 1.3e-10 41.3 0.0 0.057 13.7 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ51129.1 - 2.1e-09 37.7 4.9 0.66 10.6 0.0 7.7 7 3 1 8 8 8 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51129.1 - 2.7e-08 34.3 0.0 0.016 15.8 0.0 4.9 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ51129.1 - 2.6e-05 24.3 0.3 22 6.1 0.0 7.5 10 0 0 10 10 10 1 Ankyrin repeat PHY PF00360.20 KXZ51129.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Phytochrome region GTP_EFTU PF00009.27 KXZ51131.1 - 3.6e-10 39.7 0.2 3.8e-10 39.6 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GRDP-like PF07173.12 KXZ51134.1 - 3e-16 60.4 0.0 1.4e-11 45.3 0.0 2.7 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like DUF5102 PF17104.5 KXZ51134.1 - 0.093 12.8 1.4 0.23 11.5 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Transferase PF02458.15 KXZ51136.1 - 0.012 14.2 0.0 1.6 7.3 0.0 2.8 3 0 0 3 3 3 0 Transferase family Pkinase PF00069.25 KXZ51138.1 - 1.4e-35 123.0 0.0 7.6e-18 64.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51138.1 - 1.7e-33 116.0 0.0 1.1e-16 60.9 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase PHY PF00360.20 KXZ51139.1 - 0.071 12.4 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Phytochrome region BTB PF00651.31 KXZ51141.1 - 7.1e-15 55.2 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain FliO PF04347.13 KXZ51141.1 - 0.26 11.6 1.3 1.7 9.0 0.2 2.7 4 0 0 4 4 4 0 Flagellar biosynthesis protein, FliO PI3_PI4_kinase PF00454.27 KXZ51143.1 - 1.9e-39 136.0 0.0 2.7e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KXZ51143.1 - 1.8e-08 34.0 0.1 3.5e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 FATC domain Pkinase_Tyr PF07714.17 KXZ51145.1 - 2.9e-43 148.0 0.0 2.5e-24 86.0 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ51145.1 - 1.1e-31 110.2 0.0 1.8e-15 57.0 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ51145.1 - 0.0042 17.0 0.2 0.0042 17.0 0.2 3.6 4 2 1 5 5 5 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ51145.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myosin_head PF00063.21 KXZ51147.1 - 1.8e-188 627.9 0.0 7.3e-121 404.5 0.0 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 KXZ51147.1 - 1.3e-24 83.6 52.6 7.5e-05 22.2 1.1 8.9 9 0 0 9 9 9 7 IQ calmodulin-binding motif AAA_16 PF13191.6 KXZ51147.1 - 0.013 15.9 1.1 0.034 14.5 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXZ51147.1 - 0.046 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KXZ51147.1 - 0.053 13.0 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF769 PF05590.11 KXZ51147.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) LigA PF07746.11 KXZ51147.1 - 0.13 12.5 0.7 2.1 8.5 0.0 3.2 4 0 0 4 4 4 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Pkinase PF00069.25 KXZ51148.1 - 4.3e-60 203.3 0.0 3.8e-40 137.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51148.1 - 5e-37 127.6 0.0 9.9e-37 126.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ51148.1 - 2.3e-05 24.5 0.1 4.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ51148.1 - 0.00029 19.8 0.0 0.00066 18.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXZ51148.1 - 0.014 14.7 0.0 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like EcsC PF12787.7 KXZ51148.1 - 0.021 14.5 4.6 0.64 9.7 1.4 2.5 2 1 1 3 3 3 0 EcsC protein family CNDH2_M PF16869.5 KXZ51148.1 - 0.058 14.1 1.0 0.16 12.6 0.1 1.9 2 0 0 2 2 2 0 PF16858 PRORP PF16953.5 KXZ51149.1 - 2.8e-35 122.0 0.0 8.2e-35 120.5 0.0 1.7 2 0 0 2 2 2 1 Protein-only RNase P PPR_long PF17177.4 KXZ51149.1 - 1.5e-12 47.4 0.0 3.4e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 KXZ51149.1 - 0.00047 20.0 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain FoP_duplication PF13865.6 KXZ51149.1 - 0.0047 17.5 3.9 0.0047 17.5 3.9 3.4 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 His_Phos_1 PF00300.22 KXZ51152.1 - 9.1e-24 84.2 0.5 1.2e-23 83.9 0.5 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PsbP PF01789.16 KXZ51153.1 - 1e-06 29.0 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 PsbP Kelch_1 PF01344.25 KXZ51153.1 - 0.16 11.6 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Kelch motif Sld5 PF05916.11 KXZ51154.1 - 0.00053 20.4 0.0 0.00076 19.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein PCI PF01399.27 KXZ51155.1 - 2.8e-15 56.7 0.6 1.2e-13 51.5 0.0 3.1 3 0 0 3 3 3 1 PCI domain Pkinase_Tyr PF07714.17 KXZ51156.1 - 3.8e-43 147.6 0.0 3.5e-34 118.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ51156.1 - 1.2e-36 126.4 0.0 1.5e-27 96.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ51156.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ51156.1 - 0.039 13.9 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PS_pyruv_trans PF04230.13 KXZ51157.1 - 4.5e-12 46.5 0.0 6e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase CytB6-F_Fe-S PF08802.10 KXZ51158.1 - 6.3e-18 64.5 0.4 1.2e-17 63.6 0.4 1.5 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit Rieske PF00355.26 KXZ51158.1 - 2.5e-12 46.6 0.0 3.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain POR PF01558.18 KXZ51159.1 - 5.2e-27 95.1 0.1 5.2e-27 95.1 0.1 1.6 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 KXZ51159.1 - 7.6e-12 44.9 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function POR_N PF01855.19 KXZ51159.1 - 4.9e-11 42.8 0.2 1e-10 41.8 0.2 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TPP_enzyme_C PF02775.21 KXZ51159.1 - 5.1e-09 36.1 0.3 5.1e-09 36.1 0.3 2.5 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_21 PF14697.6 KXZ51159.1 - 5.5e-08 32.8 7.5 0.0012 18.9 0.6 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXZ51159.1 - 1e-07 32.5 7.1 3e-07 30.9 7.1 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KXZ51159.1 - 2.4e-07 30.3 20.7 7e-05 22.5 2.9 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 KXZ51159.1 - 9.4e-07 29.7 11.4 5.6e-05 24.0 12.0 2.5 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 KXZ51159.1 - 6.6e-06 26.0 21.0 4.6e-05 23.3 4.3 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KXZ51159.1 - 0.00032 20.8 16.4 0.00049 20.2 11.8 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KXZ51159.1 - 0.0023 17.9 23.3 0.0051 16.8 3.6 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 KXZ51159.1 - 0.0026 17.9 11.4 0.0026 17.9 11.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KXZ51159.1 - 0.022 15.3 14.5 0.079 13.5 11.9 2.6 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXZ51159.1 - 0.038 14.5 12.6 0.068 13.6 11.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KXZ51159.1 - 0.049 14.2 10.0 0.13 12.8 2.0 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KXZ51159.1 - 0.18 12.0 4.7 2.4 8.4 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain HPP PF04982.13 KXZ51161.1 - 1.1e-38 132.2 11.0 1.1e-38 132.2 11.0 2.2 2 1 0 2 2 2 1 HPP family DUF2809 PF10990.8 KXZ51161.1 - 0.43 11.3 2.9 0.89 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2809) Ank_4 PF13637.6 KXZ51162.1 - 1.6e-13 50.9 1.9 0.00072 20.1 0.1 6.7 7 2 1 8 8 8 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51162.1 - 2.6e-11 43.9 0.0 0.051 14.2 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ51162.1 - 1.2e-06 28.3 2.8 3.8 8.4 0.0 7.8 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 KXZ51162.1 - 1.5e-05 25.2 2.5 18 5.8 0.0 6.3 5 2 2 7 7 7 1 Ankyrin repeats (many copies) F-box PF00646.33 KXZ51162.1 - 0.0012 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 F-box domain WSC PF01822.19 KXZ51163.1 - 4.4e-17 62.0 1.1 8.6e-08 32.3 0.2 3.0 2 0 0 2 2 2 2 WSC domain SRCR PF00530.18 KXZ51163.1 - 4e-13 49.7 0.1 2e-11 44.2 0.0 3.2 2 1 0 2 2 2 1 Scavenger receptor cysteine-rich domain TRP PF06011.12 KXZ51163.1 - 0.0017 17.2 0.1 0.0044 15.8 0.1 1.6 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel JAMP PF05571.12 KXZ51163.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein ShK PF01549.24 KXZ51163.1 - 0.08 13.5 0.9 0.28 11.7 0.9 2.0 1 0 0 1 1 1 0 ShK domain-like SRCR_2 PF15494.6 KXZ51163.1 - 0.095 13.2 0.1 1.3 9.6 0.1 2.5 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain Laminin_EGF PF00053.24 KXZ51163.1 - 0.45 10.7 1.9 1.7 8.8 1.9 2.0 1 0 0 1 1 1 0 Laminin EGF domain WD40 PF00400.32 KXZ51164.1 - 2.9e-33 113.4 17.2 9.2e-07 29.5 0.3 10.9 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51164.1 - 1.6e-20 73.2 0.1 0.021 15.1 0.0 8.7 7 3 2 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KXZ51164.1 - 2.4e-06 27.1 1.8 0.057 12.7 0.0 5.4 7 0 0 7 7 7 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KXZ51164.1 - 1.9e-05 24.5 0.1 1.1 9.2 0.0 5.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXZ51164.1 - 0.034 13.1 0.9 21 3.9 0.0 4.5 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Exo_endo_phos PF03372.23 KXZ51165.1 - 0.019 14.5 0.0 0.055 13.0 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF1611_N PF17396.2 KXZ51165.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain PSRT PF07636.11 KXZ51165.1 - 1.3 8.7 5.9 3.1 7.6 5.9 1.6 1 0 0 1 1 1 0 PSRT Ank_4 PF13637.6 KXZ51168.1 - 9.7e-09 35.6 1.7 0.9 10.2 0.1 7.1 5 4 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51168.1 - 3.8e-07 30.6 0.4 0.016 15.8 0.1 3.9 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ51168.1 - 0.06 13.7 4.0 18 5.8 0.0 4.8 6 0 0 6 6 6 0 Ankyrin repeats (many copies) HAD_2 PF13419.6 KXZ51169.1 - 8.2e-08 32.5 0.0 9.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ51169.1 - 2e-05 24.6 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXZ51169.1 - 0.00029 21.2 0.0 0.00033 21.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 KXZ51171.1 - 1.9e-115 377.7 23.3 1.6e-17 63.9 0.2 8.3 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51171.1 - 1.6e-98 321.9 17.5 1e-11 45.1 0.0 12.1 6 5 7 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51171.1 - 4.1e-97 314.7 26.4 3.7e-07 30.3 0.0 16.2 14 2 2 16 16 16 14 Ankyrin repeat Ank_3 PF13606.6 KXZ51171.1 - 6.4e-92 290.4 7.1 4.6e-06 26.6 0.0 16.4 14 2 2 16 16 16 14 Ankyrin repeat Ank_5 PF13857.6 KXZ51171.1 - 1.1e-66 220.0 27.2 3.1e-09 36.9 0.0 13.8 4 4 11 15 15 15 14 Ankyrin repeats (many copies) TIR_2 PF13676.6 KXZ51171.1 - 1.6e-13 51.3 0.0 3.8e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KXZ51171.1 - 2.5e-05 24.2 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain Orn_Arg_deC_N PF02784.16 KXZ51171.1 - 0.00095 18.6 3.6 0.29 10.5 0.1 3.2 3 1 0 3 3 3 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain BTAD PF03704.17 KXZ51171.1 - 0.042 14.3 12.8 0.5 10.8 0.3 4.0 3 1 0 3 3 3 0 Bacterial transcriptional activator domain HNF-1_N PF04814.13 KXZ51171.1 - 0.067 13.8 0.1 10 6.7 0.0 3.5 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Raf1_HTH PF18579.1 KXZ51171.1 - 0.07 12.8 0.3 8.3 6.2 0.1 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain Ank_2 PF12796.7 KXZ51172.1 - 1.1e-70 234.2 10.8 8.5e-21 74.3 0.3 5.7 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ51172.1 - 3.1e-60 198.1 17.5 5.3e-07 29.8 0.0 10.8 10 1 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 KXZ51172.1 - 2.1e-58 187.4 2.3 4.7e-06 26.5 0.0 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KXZ51172.1 - 2.7e-54 180.9 8.4 2.4e-12 47.1 0.0 8.0 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ51172.1 - 5.5e-43 144.5 19.7 6.7e-09 35.8 0.2 9.6 2 2 8 10 10 10 9 Ankyrin repeats (many copies) YlmH_RBD PF17774.1 KXZ51172.1 - 0.11 12.8 2.6 38 4.7 0.0 5.2 7 0 0 7 7 7 0 Putative RNA-binding domain in YlmH Calponin PF00402.18 KXZ51172.1 - 0.27 10.9 23.3 42 3.9 0.0 9.2 10 0 0 10 10 10 0 Calponin family repeat AbiEi_3_N PF17194.4 KXZ51172.1 - 0.28 11.2 3.0 4.6 7.3 0.1 4.0 4 2 2 6 6 6 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Ribosomal_S11 PF00411.19 KXZ51172.1 - 0.55 10.7 13.2 4.3 7.8 0.5 4.1 1 1 3 4 4 4 0 Ribosomal protein S11 COR PF16095.5 KXZ51173.1 - 4.6e-23 82.0 0.0 8.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Rieske_3 PF18465.1 KXZ51173.1 - 0.05 13.8 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 Rieske 3Fe-4S Ank_2 PF12796.7 KXZ51175.1 - 1.3e-96 317.3 7.3 3.3e-16 59.6 0.0 6.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51175.1 - 6e-56 186.1 0.5 4.6e-11 43.0 0.0 7.6 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51175.1 - 9.2e-54 177.7 11.8 3e-06 27.4 0.2 10.4 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 KXZ51175.1 - 5.9e-48 155.3 0.5 0.00046 20.4 0.0 10.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 KXZ51175.1 - 2.4e-39 132.9 14.6 4e-07 30.2 0.0 9.0 2 2 7 9 9 9 9 Ankyrin repeats (many copies) COR PF16095.5 KXZ51175.1 - 6.3e-16 58.8 0.0 7.3e-13 48.8 0.0 2.4 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain TIR_2 PF13676.6 KXZ51175.1 - 9e-07 29.5 0.0 3.3e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 TIR domain CBM60 PF16841.5 KXZ51176.1 - 6.5e-05 23.3 0.0 6.3 7.3 0.0 3.5 3 0 0 3 3 3 2 Ca-dependent carbohydrate-binding module xylan-binding BNR PF02012.20 KXZ51176.1 - 0.00012 21.6 26.7 0.33 11.1 1.8 5.3 4 0 0 4 4 4 4 BNR/Asp-box repeat MAM PF00629.23 KXZ51176.1 - 0.0018 18.3 0.2 3.1 7.7 0.0 3.6 4 0 0 4 4 4 1 MAM domain, meprin/A5/mu CHB_HEX_C PF03174.13 KXZ51176.1 - 0.022 14.7 8.5 8.3 6.5 0.2 4.4 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain VID27_PH PF17747.1 KXZ51176.1 - 0.13 12.6 2.1 46 4.4 0.0 3.3 3 0 0 3 3 3 0 VID27 PH-like domain ZZ PF00569.17 KXZ51176.1 - 0.23 11.3 1.2 16 5.4 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, ZZ type Sortilin-Vps10 PF15902.5 KXZ51176.1 - 2 7.1 14.3 13 4.5 0.3 4.0 4 0 0 4 4 4 0 Sortilin, neurotensin receptor 3, Nitr_red_alph_N PF14710.6 KXZ51177.1 - 0.16 12.5 1.0 21 5.7 0.1 2.4 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal DUF397 PF04149.12 KXZ51177.1 - 0.32 11.1 5.2 3.8 7.6 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF397) TagF_N PF09867.9 KXZ51177.1 - 0.56 10.2 8.5 7.1 6.7 2.0 2.9 2 1 1 3 3 3 0 TagF N-terminal domain, Type VI secretion system-associated DUF5011 PF16403.5 KXZ51178.1 - 1.7e-13 50.5 2.8 2.5e-05 24.3 0.0 6.4 6 0 0 6 6 6 2 Domain of unknown function (DUF5011) PKD_channel PF08016.12 KXZ51178.1 - 1.1e-09 37.5 7.2 4.5e-08 32.2 6.5 2.3 2 0 0 2 2 2 2 Polycystin cation channel Big_3_2 PF12245.8 KXZ51178.1 - 0.069 13.4 6.0 5.3 7.3 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain Ion_trans PF00520.31 KXZ51178.1 - 3.6 6.7 8.6 6.7 5.9 8.6 1.3 1 0 0 1 1 1 0 Ion transport protein Ank_2 PF12796.7 KXZ51180.1 - 6.2e-12 46.0 0.8 0.0021 18.6 0.0 5.1 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51180.1 - 9.1e-09 35.7 6.3 0.035 14.7 0.3 7.2 5 3 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51180.1 - 0.00016 21.8 3.9 1.2e+02 3.8 0.0 7.5 7 1 1 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ51180.1 - 0.15 12.4 7.8 24 5.4 0.0 6.1 5 2 3 8 8 8 0 Ankyrin repeats (many copies) TPR_2 PF07719.17 KXZ51181.1 - 1.1e-20 72.0 34.8 0.0002 21.2 0.2 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ51181.1 - 1.6e-15 57.1 12.5 2.2e-13 50.2 0.3 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXZ51181.1 - 1.3e-09 37.5 4.9 0.24 11.7 0.0 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ51181.1 - 4.2e-09 36.5 55.8 0.0092 16.7 0.7 10.5 7 4 4 11 11 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ51181.1 - 1.4e-08 34.2 17.7 0.1 12.5 0.1 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ51181.1 - 1.2e-06 28.1 13.8 0.23 11.2 0.0 7.1 6 1 1 7 7 7 2 TPR repeat TPR_7 PF13176.6 KXZ51181.1 - 1.3e-06 28.0 22.2 0.019 14.9 0.0 7.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ51181.1 - 9.4e-06 25.8 7.9 6.1e-05 23.2 1.1 8.1 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ51181.1 - 2.9e-05 24.1 6.3 9.5 6.9 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ51181.1 - 0.00029 21.4 82.5 0.00031 21.3 10.6 8.9 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ51181.1 - 0.00037 20.6 9.1 0.00056 20.0 3.2 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ51181.1 - 0.007 16.9 39.4 0.068 13.7 1.3 7.9 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ51181.1 - 0.13 11.4 11.4 2.6 7.2 1.1 4.7 4 3 1 5 5 5 0 Tetratricopeptide repeat HSP70 PF00012.20 KXZ51185.1 - 0.11 10.6 0.4 13 3.8 0.2 2.7 3 0 0 3 3 3 0 Hsp70 protein Peptidase_U49 PF10463.9 KXZ51185.1 - 0.17 11.6 0.0 0.48 10.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase U49 DUF4336 PF14234.6 KXZ51187.1 - 1.8e-71 240.9 0.1 2.3e-71 240.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) WD40 PF00400.32 KXZ51188.1 - 3.9e-22 78.1 9.7 0.0097 16.7 0.0 8.7 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51188.1 - 2.3e-07 31.0 0.0 0.0081 16.4 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_6 PF13405.6 KXZ51188.1 - 5.5e-06 25.9 1.6 0.009 15.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXZ51188.1 - 8.3e-06 26.2 0.5 2.5e-05 24.6 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair Nucleoporin_N PF08801.11 KXZ51188.1 - 1.4e-05 24.1 0.0 0.27 9.9 0.0 3.2 3 0 0 3 3 3 3 Nup133 N terminal like EF-hand_1 PF00036.32 KXZ51188.1 - 1.8e-05 23.9 6.8 0.026 14.1 0.4 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KXZ51188.1 - 4.2e-05 23.3 3.8 0.0021 17.9 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ51188.1 - 0.00092 18.6 5.3 0.25 10.9 0.3 2.6 2 0 0 2 2 2 2 EF hand Nup160 PF11715.8 KXZ51188.1 - 0.027 13.2 0.2 6.3 5.3 0.0 2.8 4 0 0 4 4 4 0 Nucleoporin Nup120/160 HflK_N PF12221.8 KXZ51188.1 - 0.027 14.5 2.3 0.037 14.0 0.7 2.1 2 0 0 2 2 2 0 Bacterial membrane protein N terminal DUF5338 PF17273.2 KXZ51188.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) ThylakoidFormat PF11264.8 KXZ51189.1 - 1.5e-61 207.9 0.5 1.7e-61 207.6 0.5 1.0 1 0 0 1 1 1 1 Thylakoid formation protein SPX PF03105.19 KXZ51191.1 - 1.4 8.7 8.9 2 8.2 8.9 1.3 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 KXZ51191.1 - 1.8 8.5 33.0 0.3 11.0 29.0 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ABC1 PF03109.16 KXZ51192.1 - 4.6e-11 42.9 0.0 7.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXZ51192.1 - 4.4e-05 23.5 5.9 0.00027 21.0 0.1 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family CCDC24 PF15669.5 KXZ51192.1 - 0.4 10.5 1.4 0.6 10.0 1.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Ribosomal_L19 PF01245.20 KXZ51194.1 - 9.6e-37 125.3 0.3 1.2e-36 125.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 Exo_endo_phos PF03372.23 KXZ51195.1 - 7.3e-16 58.4 20.7 3.6e-11 43.0 0.0 3.9 2 2 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family YL1 PF05764.13 KXZ51196.1 - 0.025 14.7 0.5 0.051 13.7 0.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Usp PF00582.26 KXZ51197.1 - 8.6e-07 29.6 0.2 7.2e-06 26.6 0.2 2.3 1 1 0 1 1 1 1 Universal stress protein family Mem_trans PF03547.18 KXZ51198.1 - 1.1e-32 113.0 11.9 2.3e-17 62.5 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein Pkinase PF00069.25 KXZ51201.1 - 1.3e-17 64.0 0.0 1.6e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51201.1 - 2.4e-17 63.1 0.0 4.1e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ51202.1 - 0.00029 20.2 0.0 0.00032 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ51202.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Guanylate_cyc PF00211.20 KXZ51203.1 - 4.8e-50 169.7 0.0 7.4e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain APH PF01636.23 KXZ51204.1 - 0.0055 16.7 3.1 0.044 13.7 3.1 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RVT_2 PF07727.14 KXZ51205.1 - 1.2e-23 84.0 0.0 1.7e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GPS2_interact PF15784.5 KXZ51206.1 - 0.0097 16.3 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain ABC_membrane PF00664.23 KXZ51207.1 - 5.3e-76 255.9 16.9 3.3e-39 135.2 5.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ51207.1 - 1.9e-47 161.2 0.1 1.1e-30 106.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXZ51207.1 - 1.7e-07 30.9 1.5 0.11 11.9 0.0 3.7 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXZ51207.1 - 2.4e-05 24.8 2.3 0.2 12.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KXZ51207.1 - 3.7e-05 23.7 3.0 0.29 10.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ51207.1 - 9.4e-05 22.1 5.7 0.14 11.9 0.8 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXZ51207.1 - 0.00014 21.9 0.7 0.55 10.3 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXZ51207.1 - 0.00077 19.4 0.7 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KXZ51207.1 - 0.0036 17.1 5.1 0.35 10.6 0.9 3.5 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KXZ51207.1 - 0.0038 16.5 2.0 0.46 9.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 KXZ51207.1 - 0.0075 16.8 0.6 3.2 8.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXZ51207.1 - 0.012 14.7 1.4 0.28 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 KXZ51207.1 - 0.016 14.3 0.1 1.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KXZ51207.1 - 0.041 13.9 4.9 0.43 10.6 0.8 2.3 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 KXZ51207.1 - 0.05 12.9 3.6 2.1 7.7 0.3 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.19 KXZ51207.1 - 0.095 12.3 2.1 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KXZ51207.1 - 0.11 12.2 0.4 9.2 5.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KXZ51207.1 - 0.14 12.3 0.7 18 5.5 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KXZ51207.1 - 0.15 11.6 2.2 9 5.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KXZ51207.1 - 0.15 10.9 2.6 3.5 6.4 0.6 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KXZ51207.1 - 0.17 12.2 3.3 18 5.6 0.5 3.0 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KXZ51207.1 - 0.2 11.1 0.8 20 4.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KXZ51207.1 - 0.26 10.7 2.6 2.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DUF87 PF01935.17 KXZ51207.1 - 4.9 7.2 4.7 7.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Guanylate_cyc PF00211.20 KXZ51208.1 - 1.4e-50 171.5 0.0 1.9e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 KXZ51209.1 - 8.4e-36 123.7 0.0 7.1e-33 114.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51209.1 - 9.8e-34 116.8 0.0 1.2e-29 103.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ51209.1 - 0.0029 17.6 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ51209.1 - 0.029 13.1 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CCDC-167 PF15188.6 KXZ51210.1 - 0.0094 16.3 9.9 0.013 15.9 9.9 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Val_tRNA-synt_C PF10458.9 KXZ51210.1 - 0.58 10.5 0.0 0.58 10.5 0.0 2.9 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Pkinase PF00069.25 KXZ51211.1 - 3.1e-06 26.7 0.0 6.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ51211.1 - 7.9e-06 24.9 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ51211.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase COPI_C PF06957.11 KXZ51212.1 - 1.7e-154 514.4 0.0 2.4e-154 514.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 KXZ51212.1 - 1.3e-125 419.9 0.0 1.9e-125 419.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KXZ51212.1 - 6.1e-41 137.6 17.8 2.7e-08 34.3 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51212.1 - 3.5e-10 40.0 3.1 0.00022 21.5 0.0 5.8 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 KXZ51212.1 - 0.00039 20.1 0.0 1.1 9.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ51212.1 - 0.003 17.6 0.6 9.3 6.6 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Nup160 PF11715.8 KXZ51212.1 - 0.14 10.8 6.3 1.3 7.6 0.1 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 GTP_EFTU PF00009.27 KXZ51213.1 - 9.3e-37 126.5 0.0 1.2e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXZ51213.1 - 8.7e-20 71.1 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXZ51213.1 - 3.4e-05 23.9 0.0 0.37 10.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KXZ51213.1 - 0.042 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 PBP1_TM PF14812.6 KXZ51213.1 - 1 9.8 4.1 1.8 9.0 4.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-MYND PF01753.18 KXZ51214.1 - 5.9e-08 32.7 11.4 1.5e-07 31.4 11.4 1.7 1 1 0 1 1 1 1 MYND finger DUF1631 PF07793.11 KXZ51214.1 - 0.52 8.7 4.0 0.83 8.0 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zinc-ribbons_6 PF07191.12 KXZ51214.1 - 5.1 7.2 8.5 4.1 7.5 5.8 2.2 2 0 0 2 2 2 0 zinc-ribbons RGP PF03214.13 KXZ51215.1 - 2.6e-168 559.5 0.0 2.9e-168 559.4 0.0 1.0 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide EPL1 PF10513.9 KXZ51216.1 - 9.1e-06 26.1 0.0 1.6e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like Chorion_2 PF03964.15 KXZ51216.1 - 3 8.7 8.8 0.77 10.6 1.5 2.3 2 0 0 2 2 2 0 Chorion family 2 TPR_10 PF13374.6 KXZ51218.1 - 0.00026 20.8 5.3 0.0048 16.7 0.2 4.7 5 1 0 5 5 5 3 Tetratricopeptide repeat DUF1910 PF08928.10 KXZ51218.1 - 0.028 14.4 0.0 0.12 12.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) TPR_7 PF13176.6 KXZ51218.1 - 2.8 8.2 10.5 0.55 10.4 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat MORN PF02493.20 KXZ51219.1 - 1.2e-22 78.4 22.0 1e-05 25.1 1.1 5.9 6 0 0 6 6 6 5 MORN repeat Pkinase_Tyr PF07714.17 KXZ51223.1 - 4.2e-47 160.6 0.0 6.3e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ51223.1 - 1.1e-45 156.1 0.0 1.6e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ51223.1 - 1.2e-05 24.3 0.0 2.7e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXZ51223.1 - 0.048 13.6 1.1 0.21 11.5 0.0 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family adh_short PF00106.25 KXZ51224.1 - 2.1e-32 112.1 0.1 2.7e-32 111.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ51224.1 - 5.6e-27 94.8 0.1 7e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ51224.1 - 0.0073 16.2 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXZ51224.1 - 0.0086 15.6 0.0 0.046 13.2 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family zf-met PF12874.7 KXZ51226.1 - 9.9e-07 28.9 0.1 1.6e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXZ51226.1 - 6.4e-05 23.1 0.0 9.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXZ51226.1 - 0.015 15.6 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXZ51226.1 - 0.034 15.0 0.1 0.061 14.2 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXZ51226.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger CDI PF02234.19 KXZ51226.1 - 4.2 7.6 4.3 16 5.8 1.5 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor TPP_enzyme_N PF02776.18 KXZ51227.1 - 1.7e-25 89.6 1.8 1.7e-25 89.6 1.8 4.2 4 1 1 5 5 5 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXZ51227.1 - 2.7e-18 66.2 14.3 9.3e-18 64.5 0.1 4.8 3 1 1 4 4 4 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain polyprenyl_synt PF00348.17 KXZ51229.1 - 2.3e-72 243.1 0.1 2.7e-72 242.9 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KXZ51229.1 - 0.027 14.1 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 CHASE8 PF17152.4 KXZ51229.1 - 0.037 14.3 0.2 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Periplasmic sensor domain RNA_pol_L_2 PF13656.6 KXZ51230.1 - 2.3e-24 84.9 0.0 2.9e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXZ51230.1 - 3e-11 42.6 0.0 4.2e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Lyase_1 PF00206.20 KXZ51231.1 - 6e-57 193.4 0.0 8.3e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 KXZ51231.1 - 2.8e-49 166.0 0.0 5.8e-49 165.0 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal FTHFS PF01268.19 KXZ51232.1 - 3.9e-259 860.5 0.1 4.4e-259 860.3 0.1 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 KXZ51232.1 - 0.068 13.2 0.6 0.18 11.9 0.5 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TnpV PF14198.6 KXZ51232.1 - 0.2 11.7 0.0 11 6.1 0.0 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV LSM PF01423.22 KXZ51233.1 - 8.8e-19 67.0 0.3 1e-18 66.8 0.3 1.1 1 0 0 1 1 1 1 LSM domain SET PF00856.28 KXZ51234.1 - 2.6e-10 40.9 0.0 3.5e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 SET domain OKR_DC_1 PF01276.20 KXZ51235.1 - 1.2e-50 172.5 0.0 1.8e-37 129.1 0.0 3.0 2 1 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 KXZ51235.1 - 8.4e-08 32.6 0.0 2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain SepSecS PF05889.13 KXZ51235.1 - 0.003 16.3 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 KXZ51235.1 - 0.053 12.8 0.7 0.1 11.9 0.7 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXZ51235.1 - 0.085 11.4 0.0 1.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 KXZ51235.1 - 0.094 11.4 1.0 0.17 10.6 1.0 1.4 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Beta_helix PF13229.6 KXZ51236.1 - 3.2e-08 33.6 0.9 0.0014 18.5 0.0 3.0 1 1 0 2 2 2 2 Right handed beta helix region FKBP_C PF00254.28 KXZ51237.1 - 4.5e-19 68.6 0.0 6.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-CCCH PF00642.24 KXZ51238.1 - 2e-05 24.3 5.6 2e-05 24.3 5.6 3.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KXZ51238.1 - 2.7 8.6 21.0 3.9 8.1 2.1 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Cons_hypoth95 PF03602.15 KXZ51239.1 - 1.3e-42 145.5 0.0 2.5e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DUF465 PF04325.13 KXZ51239.1 - 0.1 12.7 2.1 0.23 11.6 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) MethyltransfD12 PF02086.15 KXZ51239.1 - 0.26 10.9 0.0 0.46 10.1 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase SpoU_methylase PF00588.19 KXZ51241.1 - 8.9e-27 94.0 0.0 1.6e-23 83.5 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KXZ51241.1 - 1.5e-12 47.6 0.0 2.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Zip PF02535.22 KXZ51242.1 - 1.8e-28 99.7 1.5 3.2e-28 98.9 1.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter CstA PF02554.14 KXZ51242.1 - 0.0002 20.4 1.1 0.00026 20.0 1.1 1.1 1 0 0 1 1 1 1 Carbon starvation protein CstA DUF4191 PF13829.6 KXZ51242.1 - 0.62 9.4 3.0 2.2 7.6 2.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Zip PF02535.22 KXZ51243.1 - 6.3e-26 91.4 2.2 1.5e-25 90.1 2.2 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1097 PF06496.11 KXZ51243.1 - 0.007 16.5 4.7 0.007 16.5 4.7 2.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1097) DUF4191 PF13829.6 KXZ51243.1 - 0.0086 15.4 0.7 0.015 14.6 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) Zip PF02535.22 KXZ51244.1 - 5.5e-32 111.3 6.0 1e-31 110.4 6.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4191 PF13829.6 KXZ51244.1 - 0.013 14.8 0.9 0.013 14.8 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) E1-E2_ATPase PF00122.20 KXZ51244.1 - 0.12 11.9 1.7 0.74 9.3 0.0 2.6 3 0 0 3 3 3 0 E1-E2 ATPase DUF4149 PF13664.6 KXZ51244.1 - 1.3 9.4 5.1 0.92 9.9 0.1 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4149) DAGK_cat PF00781.24 KXZ51247.1 - 1.7e-21 76.1 0.0 1.3e-20 73.3 0.0 2.1 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KXZ51247.1 - 0.0025 17.0 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Gln-synt_N PF03951.19 KXZ51248.1 - 2.2e-17 62.5 0.0 8.9e-17 60.6 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 KXZ51248.1 - 1.3e-12 47.4 0.0 4.4e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXZ51249.1 - 2.2e-17 62.6 0.0 8.6e-17 60.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 KXZ51249.1 - 1.2e-12 47.5 0.0 4.2e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain TFIID_20kDa PF03847.13 KXZ51250.1 - 9.1e-12 45.3 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Spt5_N PF11942.8 KXZ51250.1 - 0.042 14.8 4.4 4 8.5 0.0 2.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal HEAT PF02985.22 KXZ51251.1 - 2.9e-10 39.5 13.2 0.00069 19.7 0.1 6.6 5 1 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KXZ51251.1 - 1.7 9.1 34.5 2.5 8.6 0.4 6.1 4 1 0 5 5 5 0 HEAT repeats Na_Ca_ex PF01699.24 KXZ51252.1 - 1.2e-32 113.0 41.2 7.3e-17 61.7 16.9 2.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein BatA PF07584.11 KXZ51252.1 - 9.9 6.6 9.7 0.18 12.2 0.4 2.8 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Proteasome PF00227.26 KXZ51253.1 - 5e-32 110.9 0.0 5.8e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NblA PF04485.12 KXZ51253.1 - 0.087 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA GRASP55_65 PF04495.14 KXZ51253.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Ammonium_transp PF00909.21 KXZ51254.1 - 1.1e-80 271.3 19.6 1.1e-80 271.3 19.6 1.7 2 0 0 2 2 2 1 Ammonium Transporter Family Patatin PF01734.22 KXZ51255.1 - 5.8e-07 29.9 0.3 2.2e-06 28.0 0.3 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase ABC2_membrane PF01061.24 KXZ51256.1 - 8e-39 133.2 13.4 1.1e-38 132.8 13.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ51256.1 - 6.9e-26 91.4 0.0 1e-25 90.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ51256.1 - 4.9e-05 23.3 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ51256.1 - 7.7e-05 22.2 0.1 0.0091 15.4 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXZ51256.1 - 0.00033 20.6 0.3 0.00074 19.5 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXZ51256.1 - 0.00045 20.6 0.0 0.00096 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXZ51256.1 - 0.00079 19.1 0.2 0.0018 18.0 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXZ51256.1 - 0.0021 18.3 0.1 0.005 17.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ51256.1 - 0.0043 17.6 0.0 0.009 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXZ51256.1 - 0.0091 15.6 0.1 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXZ51256.1 - 0.014 15.7 0.0 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXZ51256.1 - 0.022 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 KXZ51256.1 - 0.03 14.8 0.1 0.049 14.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KXZ51256.1 - 0.036 13.8 0.1 0.079 12.7 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase MMR_HSR1 PF01926.23 KXZ51256.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 KXZ51256.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KXZ51256.1 - 0.069 13.1 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KXZ51256.1 - 0.08 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KXZ51256.1 - 0.094 12.0 10.8 0.31 10.3 10.8 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.18 KXZ51256.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXZ51256.1 - 0.17 11.6 0.0 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXZ51256.1 - 0.22 11.9 0.1 0.63 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 KXZ51257.1 - 7.1e-42 143.2 14.2 9.5e-42 142.8 14.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ51257.1 - 1e-22 81.1 0.0 1.6e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ51257.1 - 0.00055 19.8 0.0 0.81 9.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXZ51257.1 - 0.005 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_2 PF12679.7 KXZ51257.1 - 0.0094 15.3 11.8 0.029 13.7 11.8 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 KXZ51257.1 - 0.024 14.1 0.0 0.2 11.1 0.0 2.0 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KXZ51257.1 - 0.12 12.0 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXZ51257.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KXZ51257.1 - 0.13 12.5 0.0 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXZ51257.1 - 0.2 11.6 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KXZ51257.1 - 0.22 12.1 0.0 0.47 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KXZ51257.1 - 5.5 6.0 12.9 6.3 5.8 12.1 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3429 PF11911.8 KXZ51259.1 - 1.2e-33 116.4 13.5 1.7e-33 115.9 13.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) YrhC PF14143.6 KXZ51259.1 - 0.078 13.1 0.1 0.28 11.3 0.0 2.0 2 1 0 2 2 2 0 YrhC-like protein Ribosomal_S19 PF00203.21 KXZ51260.1 - 0.11 12.3 0.2 9 6.3 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S19 LRR_9 PF14580.6 KXZ51262.1 - 2e-21 76.3 19.2 1.3e-17 63.8 6.6 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KXZ51262.1 - 2.9e-18 65.6 22.9 3.7e-08 33.5 4.4 4.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ51262.1 - 1.6e-09 37.4 21.3 2.7e-06 27.0 8.7 3.3 2 1 0 3 3 3 2 Leucine rich repeat SF3A3 PF16837.5 KXZ51262.1 - 0.025 15.1 4.3 12 6.5 0.1 3.6 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF4851 PF16143.5 KXZ51262.1 - 0.062 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) HXXSHH PF07586.11 KXZ51262.1 - 6.7 6.2 9.2 1.3 8.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1552) eIF-5_eIF-2B PF01873.17 KXZ51263.1 - 2.9e-37 127.1 0.0 4.5e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KXZ51263.1 - 0.086 12.4 0.0 0.24 10.9 0.0 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 KXZ51263.1 - 0.092 13.1 0.2 0.23 11.9 0.1 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar Rubredoxin_2 PF18073.1 KXZ51263.1 - 0.21 11.3 2.2 10 6.0 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Guanylate_cyc PF00211.20 KXZ51265.1 - 3.4e-49 167.0 0.0 5.1e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ank_2 PF12796.7 KXZ51267.1 - 7.4e-07 29.7 0.0 1.5 9.4 0.0 4.7 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51267.1 - 2e-06 28.2 0.4 1 10.1 0.0 6.0 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51267.1 - 3.4e-05 23.9 0.8 45 5.1 0.0 7.2 9 0 0 9 9 9 0 Ankyrin repeat Ank_5 PF13857.6 KXZ51267.1 - 0.00028 21.1 0.7 35 4.9 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeats (many copies) SelB-wing_1 PF09105.10 KXZ51267.1 - 0.025 14.6 2.0 0.77 9.8 0.0 3.3 3 0 0 3 3 3 0 Elongation factor SelB, winged helix zf-4CXXC_R1 PF10497.9 KXZ51268.1 - 1.1e-16 60.8 13.3 5.8e-16 58.5 13.3 2.1 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Nop14 PF04147.12 KXZ51268.1 - 4.6 5.3 32.7 7 4.7 32.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 KXZ51268.1 - 9 5.6 31.3 0.23 10.8 24.8 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Phage_int_SAM_1 PF02899.17 KXZ51269.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Flavin_Reduct PF01613.18 KXZ51271.1 - 1.8e-22 80.0 0.0 3.7e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Flavin reductase like domain Flavodoxin_1 PF00258.25 KXZ51271.1 - 5.2e-07 30.0 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KXZ51271.1 - 0.0051 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin domain DUF3619 PF12279.8 KXZ51271.1 - 0.86 9.9 6.1 1.1 9.6 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) Ion_trans PF00520.31 KXZ51272.1 - 7.6e-10 38.4 9.7 1.7e-09 37.3 9.7 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXZ51272.1 - 4.2e-09 36.2 2.3 1e-08 35.0 2.3 1.7 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 KXZ51272.1 - 0.0027 17.7 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF493 PF04359.14 KXZ51273.1 - 1e-14 54.9 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF493) Hep_59 PF07052.11 KXZ51274.1 - 0.098 13.4 4.7 0.58 10.9 0.1 3.4 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 RVT_1 PF00078.27 KXZ51275.1 - 6.1e-33 114.2 0.0 1e-32 113.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KXZ51278.1 - 2.6e-08 33.6 0.0 4.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51278.1 - 0.00018 20.9 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ51279.1 - 3.5e-31 108.5 0.0 3.2e-30 105.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51279.1 - 3.2e-27 95.5 0.0 1.9e-15 56.9 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Ank_5 PF13857.6 KXZ51279.1 - 8.8e-18 64.1 1.1 4.2e-10 39.7 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51279.1 - 2.3e-15 56.9 0.0 8.4e-15 55.1 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ51279.1 - 9.6e-15 54.3 0.0 1.3e-06 28.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXZ51279.1 - 9.5e-14 51.6 0.3 1.1e-09 38.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) U-box PF04564.15 KXZ51279.1 - 2.6e-13 49.9 0.0 5.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain Ank_3 PF13606.6 KXZ51279.1 - 3e-13 48.6 0.0 0.00082 19.6 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat zf-NOSIP PF15906.5 KXZ51279.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein EccE PF11203.8 KXZ51279.1 - 4.8 7.6 6.6 1.5 9.2 0.5 2.6 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Gly_transf_sug PF04488.15 KXZ51281.1 - 1.8e-11 44.5 0.1 4.1e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif APH PF01636.23 KXZ51283.1 - 0.03 14.2 1.5 0.14 12.1 0.4 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family RSN1_TM PF13967.6 KXZ51284.1 - 6.1e-11 42.3 3.7 7.6e-11 42.0 0.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Sporozoite_P67 PF05642.11 KXZ51284.1 - 0.29 9.2 1.9 0.64 8.0 1.9 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen RSN1_7TM PF02714.15 KXZ51285.1 - 4.9e-30 104.8 6.4 8.9e-15 54.7 0.9 2.1 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXZ51285.1 - 9.3e-08 32.5 0.8 4.1e-07 30.4 0.0 2.3 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Hydrolase_4 PF12146.8 KXZ51286.1 - 3.9e-11 42.7 0.2 0.00016 21.0 0.0 3.4 3 0 0 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ51286.1 - 0.0002 21.1 0.0 0.29 10.8 0.0 3.2 3 1 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_M11 PF05548.11 KXZ51287.1 - 4.1e-59 200.3 1.2 6e-59 199.7 1.2 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Cu-binding_MopE PF11617.8 KXZ51287.1 - 3.2e-05 24.0 3.0 7.9e-05 22.7 3.0 1.7 1 0 0 1 1 1 1 Putative metal-binding motif AZUL PF16558.5 KXZ51287.1 - 0.041 14.1 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Peptidase_M66 PF10462.9 KXZ51287.1 - 0.062 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Bim_N PF06773.11 KXZ51287.1 - 0.065 12.9 1.5 0.2 11.3 1.5 1.8 1 0 0 1 1 1 0 Bim protein N-terminus Peptidase_S8 PF00082.22 KXZ51288.1 - 2.2e-43 148.6 0.2 2.2e-43 148.6 0.2 2.3 2 0 0 2 2 2 1 Subtilase family DUF3716 PF12511.8 KXZ51289.1 - 0.05 13.7 2.0 0.1 12.6 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF4023 PF13215.6 KXZ51289.1 - 0.38 10.8 2.4 0.89 9.6 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) A_deaminase PF00962.22 KXZ51290.1 - 2.1e-119 398.7 0.6 2.6e-119 398.4 0.6 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase HECT PF00632.25 KXZ51291.1 - 6.6e-38 130.9 0.0 1.6e-30 106.6 0.0 2.2 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) MSSP PF03940.13 KXZ51291.1 - 1 9.0 12.0 10 5.8 12.0 2.8 1 0 0 1 1 1 0 Male specific sperm protein LRR_8 PF13855.6 KXZ51293.1 - 2.9e-05 23.7 0.3 0.00056 19.6 0.5 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KXZ51293.1 - 0.00029 21.2 5.5 0.00045 20.5 1.3 2.9 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ51293.1 - 0.0049 17.2 3.1 27 5.8 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KXZ51293.1 - 0.012 15.6 0.1 26 5.2 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat PDEase_I PF00233.19 KXZ51294.1 - 1.7e-69 234.1 0.0 2.3e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 KXZ51295.1 - 2.8e-68 230.2 0.0 3.6e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase JSRP PF15312.6 KXZ51298.1 - 6.3 6.8 7.2 1.6 8.7 1.0 2.7 3 0 0 3 3 3 0 Junctional sarcoplasmic reticulum protein Neurensin PF14927.6 KXZ51302.1 - 0.01 15.5 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 0 Neurensin DUF3899 PF13038.6 KXZ51302.1 - 0.016 15.7 0.0 0.018 15.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Vac7 PF12751.7 KXZ51302.1 - 0.073 12.5 0.1 0.081 12.4 0.1 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF1778 PF08681.11 KXZ51303.1 - 0.035 14.0 0.8 0.089 12.7 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) DUF2017 PF09438.10 KXZ51303.1 - 0.054 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) DUF5542 PF17696.1 KXZ51303.1 - 1.3 9.2 3.9 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5542) pPIWI_RE_Y PF18156.1 KXZ51305.1 - 0.052 14.0 0.2 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 pPIWI_RE three-gene island domain Y DUF3035 PF11233.8 KXZ51305.1 - 0.11 12.7 0.7 0.2 11.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) LapA_dom PF06305.11 KXZ51306.1 - 0.07 12.9 1.0 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SBP_bac_1 PF01547.25 KXZ51308.1 - 5.6e-09 36.4 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Guanylate_cyc PF00211.20 KXZ51308.1 - 0.0045 16.6 0.1 0.81 9.3 0.0 2.6 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain PK PF00224.21 KXZ51309.1 - 9.5e-156 518.0 4.3 1.5e-155 517.3 4.3 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXZ51309.1 - 3.2e-23 82.2 3.3 1.7e-22 79.8 1.6 2.7 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXZ51309.1 - 0.0033 16.6 0.2 0.0075 15.4 0.2 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Gp138_N PF18352.1 KXZ51309.1 - 0.042 13.9 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain TRAM_LAG1_CLN8 PF03798.16 KXZ51310.1 - 3.3e-30 105.3 17.0 4.6e-30 104.8 17.0 1.2 1 0 0 1 1 1 1 TLC domain Guanylate_cyc PF00211.20 KXZ51311.1 - 1.8e-11 44.0 0.1 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SBP_bac_1 PF01547.25 KXZ51311.1 - 1.4e-06 28.5 0.0 7.3e-06 26.1 0.0 2.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KXZ51311.1 - 1.2e-05 25.3 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein RPAP2_Rtr1 PF04181.13 KXZ51312.1 - 2.4e-05 24.6 0.0 3.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF883 PF05957.13 KXZ51312.1 - 3.1 8.4 11.8 0.11 13.1 1.9 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ank_2 PF12796.7 KXZ51315.1 - 2e-17 63.5 0.6 4.2e-08 33.7 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Autophagy_act_C PF03987.15 KXZ51315.1 - 7.6e-13 48.8 1.2 1.4e-12 48.0 1.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ank_3 PF13606.6 KXZ51315.1 - 2.2e-11 42.9 3.6 0.0075 16.7 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXZ51315.1 - 6.2e-09 35.9 8.7 0.12 12.8 0.1 6.2 3 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ51315.1 - 1.3e-08 35.2 2.6 0.36 11.5 0.0 5.0 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51315.1 - 0.00077 19.8 8.7 0.2 12.2 0.2 5.6 4 2 0 4 4 4 1 Ankyrin repeat RabGAP-TBC PF00566.18 KXZ51316.1 - 1.3e-28 100.1 0.0 1.9e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_L13 PF00572.18 KXZ51317.1 - 7.5e-11 42.4 0.1 7.9e-09 35.8 0.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L13 SBF PF01758.16 KXZ51318.1 - 4.9e-34 117.7 20.2 4.9e-34 117.7 20.2 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 KXZ51318.1 - 1.4e-16 60.8 25.6 1.7e-16 60.5 25.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Stomoxyn PF11585.8 KXZ51318.1 - 1.6 8.8 6.4 3.6 7.7 6.4 1.6 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn UDPG_MGDP_dh_C PF03720.15 KXZ51319.1 - 1.3e-31 109.1 0.0 3.5e-31 107.7 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KXZ51319.1 - 3.1e-29 101.0 0.0 5.2e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KXZ51319.1 - 2.5e-08 33.7 0.0 4.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1326 PF07040.11 KXZ51320.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) CBM_4_9 PF02018.17 KXZ51321.1 - 2.3e-05 24.7 2.4 0.0046 17.2 0.2 2.8 3 0 0 3 3 3 2 Carbohydrate binding domain G8 PF10162.9 KXZ51321.1 - 0.0068 16.5 0.0 0.092 12.8 0.0 2.6 2 0 0 2 2 2 1 G8 domain Phage_H_T_join PF05521.11 KXZ51321.1 - 0.054 14.0 0.2 13 6.4 0.0 2.6 2 0 0 2 2 2 0 Phage head-tail joining protein RTA1 PF04479.13 KXZ51322.1 - 8.5e-49 166.0 12.5 8.5e-49 166.0 12.5 1.9 2 0 0 2 2 2 1 RTA1 like protein Pkinase_Tyr PF07714.17 KXZ51323.1 - 6.6e-06 25.6 0.0 7.2e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ51323.1 - 1.7e-05 24.4 0.0 1.9e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KXZ51324.1 - 2.1e-07 31.4 0.1 0.0005 20.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51324.1 - 4.8e-07 30.2 2.8 0.27 11.9 0.1 4.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ51324.1 - 6.6e-07 29.5 0.1 0.41 11.0 0.0 4.0 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51324.1 - 0.0043 17.5 0.7 10 7.1 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat ERAP1_C PF11838.8 KXZ51324.1 - 0.021 14.4 1.3 0.1 12.1 0.3 2.0 2 0 0 2 2 2 0 ERAP1-like C-terminal domain Exo_endo_phos PF03372.23 KXZ51325.1 - 1.9e-20 73.4 0.2 4.5e-20 72.2 0.2 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.28 KXZ51326.1 - 0.002 18.5 0.0 0.0048 17.3 0.0 1.7 1 1 0 1 1 1 1 SET domain MMR_HSR1 PF01926.23 KXZ51328.1 - 5.1e-19 68.5 0.2 1.2e-15 57.6 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.11 KXZ51328.1 - 7.9e-16 57.9 18.5 7.9e-16 57.9 18.5 2.9 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.18 KXZ51328.1 - 4.2e-11 42.6 0.0 1.6e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXZ51328.1 - 3.8e-05 23.3 0.0 0.0033 17.0 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXZ51328.1 - 0.00022 21.2 0.2 0.076 12.9 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KXZ51328.1 - 0.0032 16.8 0.1 0.025 13.9 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Gtr1_RagA PF04670.12 KXZ51328.1 - 0.019 14.3 0.0 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Peptidase_S8_N PF16361.5 KXZ51328.1 - 0.024 15.1 0.1 0.075 13.5 0.1 1.8 1 0 0 1 1 1 0 N-terminal of Subtilase family Roc PF08477.13 KXZ51328.1 - 0.041 14.1 0.2 1.8 8.8 0.1 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KXZ51328.1 - 0.13 12.3 8.4 0.053 13.6 0.7 3.3 3 1 0 3 3 3 0 Dynamin family MeaB PF03308.16 KXZ51328.1 - 0.82 8.6 4.5 0.12 11.4 0.2 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mit_KHE1 PF10173.9 KXZ51328.1 - 9 6.3 6.3 8.8 6.4 5.2 1.6 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DNA_photolyase PF00875.18 KXZ51329.1 - 2.2e-32 112.3 0.0 4.2e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase GDC-P PF02347.16 KXZ51330.1 - 1.7e-188 626.9 0.8 1.1e-177 591.2 0.0 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KXZ51330.1 - 5.7e-07 29.1 0.5 1.7e-06 27.5 0.5 1.8 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXZ51330.1 - 5.3e-05 22.4 2.8 0.0016 17.5 0.5 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXZ51330.1 - 0.0011 17.6 0.1 0.0025 16.4 0.1 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GLTT PF01744.20 KXZ51331.1 - 1.8 8.4 44.7 2.9 7.7 4.9 6.4 2 1 5 7 7 7 0 GLTT repeat (6 copies) DNA_photolyase PF00875.18 KXZ51333.1 - 7.5e-19 68.3 0.0 1.1e-17 64.5 0.0 2.3 1 1 0 1 1 1 1 DNA photolyase TOM20_plant PF06552.12 KXZ51334.1 - 5.5e-35 120.8 0.0 6.9e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 KXZ51334.1 - 1.9e-07 30.6 0.0 6.2e-06 25.8 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 KXZ51334.1 - 0.028 14.5 5.2 1.9 8.8 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ51334.1 - 0.06 13.9 0.0 13 6.4 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ51334.1 - 0.094 13.6 0.1 6.1 7.9 0.0 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ51334.1 - 0.19 11.6 4.7 24 4.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat FKBP_C PF00254.28 KXZ51335.1 - 3.1e-18 65.9 0.0 5.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase_Tyr PF07714.17 KXZ51336.1 - 4.5e-64 216.2 0.0 5.5e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ51336.1 - 7.7e-53 179.5 0.0 1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ51336.1 - 5.5e-05 22.1 0.0 7.3e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ51336.1 - 0.00057 19.9 4.8 0.0098 15.8 0.1 3.3 2 2 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ51336.1 - 0.031 13.2 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KXZ51336.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXZ51336.1 - 0.13 11.6 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.26 KXZ51337.1 - 5e-17 62.0 0.0 8.2e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXZ51337.1 - 7.8e-11 42.2 0.0 9.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Cupin_2 PF07883.11 KXZ51338.1 - 3.7e-08 32.9 0.0 5.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 KXZ51338.1 - 0.067 13.1 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Pkinase PF00069.25 KXZ51339.1 - 2.7e-21 76.1 0.0 8.6e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51339.1 - 1.8e-11 43.9 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1633 PF07794.11 KXZ51339.1 - 0.0038 15.5 0.0 0.0049 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) Kinase-like PF14531.6 KXZ51339.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ51339.1 - 0.013 15.4 0.5 0.028 14.3 0.5 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ51339.1 - 0.053 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ51339.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SBP_bac_8 PF13416.6 KXZ51340.1 - 0.0028 17.5 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXZ51340.1 - 0.0029 17.6 0.0 0.14 12.1 0.0 2.6 3 0 0 3 3 3 1 Bacterial extracellular solute-binding protein Guanylate_cyc PF00211.20 KXZ51340.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain DUF3515 PF12028.8 KXZ51340.1 - 0.22 11.2 5.8 0.4 10.4 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) Guanylate_cyc PF00211.20 KXZ51342.1 - 1.3e-07 31.4 0.0 5.5e-05 22.9 0.0 3.0 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain SBP_bac_8 PF13416.6 KXZ51342.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KXZ51343.1 - 1.6e-06 28.1 0.2 8.6e-06 25.8 0.2 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXZ51343.1 - 2.2e-06 27.8 0.1 1.1e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein Guanylate_cyc PF00211.20 KXZ51343.1 - 0.0049 16.5 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain FA_FANCE PF11510.8 KXZ51344.1 - 8e-09 35.2 1.1 0.00022 20.7 0.0 2.0 2 0 0 2 2 2 2 Fanconi Anaemia group E protein FANCE cobW PF02492.19 KXZ51346.1 - 8.2e-39 133.0 0.0 2e-29 102.4 0.0 2.6 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ51346.1 - 2.6e-22 78.6 1.2 3.4e-16 58.9 0.0 3.1 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain Thioredoxin PF00085.20 KXZ51346.1 - 0.036 14.0 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin tRNA_anti-codon PF01336.25 KXZ51346.1 - 0.037 14.0 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain TsaE PF02367.17 KXZ51346.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PHD PF00628.29 KXZ51347.1 - 2.2e-06 27.5 6.3 4.1e-06 26.6 6.3 1.5 1 0 0 1 1 1 1 PHD-finger DUF2358 PF10184.9 KXZ51347.1 - 0.0035 17.6 0.0 0.0072 16.6 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) C1_1 PF00130.22 KXZ51347.1 - 0.039 13.9 0.8 0.039 13.9 0.8 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SnoaL_2 PF12680.7 KXZ51347.1 - 0.069 13.8 1.0 0.22 12.2 0.1 2.2 2 0 0 2 2 2 0 SnoaL-like domain PHD_2 PF13831.6 KXZ51347.1 - 0.66 9.6 6.2 1.9 8.1 6.2 1.8 1 1 0 1 1 1 0 PHD-finger GST_C PF00043.25 KXZ51349.1 - 0.0022 18.2 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXZ51349.1 - 0.0098 16.1 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ51349.1 - 0.05 13.6 0.4 0.096 12.7 0.4 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PHD_2 PF13831.6 KXZ51350.1 - 0.00054 19.5 1.1 0.00084 18.8 1.1 1.3 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KXZ51350.1 - 0.0038 17.1 1.5 0.0064 16.4 1.5 1.3 1 0 0 1 1 1 1 PHD-finger DUF488 PF04343.13 KXZ51351.1 - 2.8e-32 111.9 0.1 4.1e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF488 BTB PF00651.31 KXZ51353.1 - 4.4e-12 46.2 0.0 9.1e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pkinase_Tyr PF07714.17 KXZ51355.1 - 1.4e-08 34.3 0.0 3.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ51355.1 - 1.2e-07 31.4 0.0 6.9e-06 25.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51356.1 - 1.7e-44 152.1 0.0 5.6e-42 143.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ51356.1 - 7.5e-44 150.1 0.0 2.1e-41 142.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ51356.1 - 0.0028 17.6 0.1 0.0028 17.6 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ51356.1 - 0.069 11.9 0.0 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase XK-related PF09815.9 KXZ51357.1 - 8.1e-14 51.4 9.8 1.1e-13 51.0 9.8 1.1 1 0 0 1 1 1 1 XK-related protein Hydrolase_4 PF12146.8 KXZ51358.1 - 2.6e-05 23.6 0.1 0.00017 21.0 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S51 PF03575.17 KXZ51358.1 - 0.041 13.5 0.0 0.079 12.6 0.0 1.5 1 1 0 1 1 1 0 Peptidase family S51 THB PF18362.1 KXZ51358.1 - 0.15 11.7 0.6 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Tri-helix bundle domain DUF2353 PF09789.9 KXZ51359.1 - 0.0035 16.8 1.6 0.014 14.8 1.6 1.9 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) APG17 PF04108.12 KXZ51359.1 - 0.035 13.2 0.1 0.6 9.2 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 Leu_zip PF15294.6 KXZ51359.1 - 0.038 13.5 3.3 0.05 13.1 0.5 2.3 2 0 0 2 2 2 0 Leucine zipper DUF3496 PF12001.8 KXZ51359.1 - 0.21 12.0 1.0 2 8.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) YabA PF06156.13 KXZ51359.1 - 0.25 12.0 10.7 0.35 11.5 2.0 2.8 3 1 0 3 3 2 0 Initiation control protein YabA Fez1 PF06818.15 KXZ51359.1 - 0.39 11.1 3.9 2.9 8.3 0.7 2.1 2 0 0 2 2 2 0 Fez1 DHR10 PF18595.1 KXZ51359.1 - 0.72 9.9 19.1 0.21 11.7 3.2 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain PV-1 PF06637.11 KXZ51359.1 - 0.73 8.6 3.5 1.3 7.8 3.5 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Spc7 PF08317.11 KXZ51359.1 - 0.81 8.5 7.7 4.9 5.9 2.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CorA PF01544.18 KXZ51359.1 - 1.2 8.4 3.4 23 4.2 1.7 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Rootletin PF15035.6 KXZ51359.1 - 1.2 9.1 16.6 4.7 7.2 14.0 2.4 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4201 PF13870.6 KXZ51359.1 - 1.5 8.6 8.5 0.29 10.9 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ERM PF00769.19 KXZ51359.1 - 1.8 8.3 17.1 0.75 9.6 0.9 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family KASH_CCD PF14662.6 KXZ51359.1 - 3.8 7.3 9.3 7.7 6.3 3.4 2.6 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KXZ51359.1 - 5.8 6.2 7.6 13 5.0 0.3 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 KXZ51359.1 - 6.6 6.5 5.7 27 4.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) BST2 PF16716.5 KXZ51359.1 - 7.5 7.2 9.0 0.59 10.8 0.6 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 3HCDH_N PF02737.18 KXZ51360.1 - 1.4e-50 171.7 0.1 1.8e-50 171.3 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXZ51360.1 - 1.9e-27 95.7 0.0 4.5e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXZ51360.1 - 0.00016 21.9 1.0 0.00032 20.9 1.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KXZ51360.1 - 0.016 14.6 0.9 0.05 13.0 0.2 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KXZ51360.1 - 0.039 13.5 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_Gly3P_dh_N PF01210.23 KXZ51360.1 - 0.062 13.3 0.3 0.5 10.3 0.1 2.3 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 KXZ51360.1 - 0.077 12.6 0.3 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KXZ51360.1 - 0.15 12.6 1.5 0.44 11.1 1.5 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 KXZ51361.1 - 8.4e-06 25.3 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ51361.1 - 1.1e-05 24.5 0.0 1.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ51361.1 - 0.00055 19.9 0.1 0.00055 19.9 0.1 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ51361.1 - 0.00057 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ51361.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4401 PF14351.6 KXZ51362.1 - 0.059 12.7 2.1 0.077 12.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF924 PF06041.11 KXZ51363.1 - 1.5e-53 181.6 0.0 1.7e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) PLA2_B PF01735.18 KXZ51365.1 - 3.8e-05 22.3 1.1 6.1e-05 21.6 1.1 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.18 KXZ51366.1 - 6e-06 24.9 0.9 1.5e-05 23.6 0.1 2.0 3 0 0 3 3 3 1 Lysophospholipase catalytic domain DUF2201 PF09967.9 KXZ51366.1 - 0.1 12.7 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 VWA-like domain (DUF2201) Patatin PF01734.22 KXZ51366.1 - 0.12 12.6 2.4 0.34 11.1 0.1 2.6 2 1 1 3 3 3 0 Patatin-like phospholipase COPI_C PF06957.11 KXZ51367.1 - 6e-117 390.8 3.2 8.5e-105 350.8 0.0 2.1 1 1 1 2 2 2 2 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 KXZ51367.1 - 1.2e-110 370.7 0.0 1.6e-110 370.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KXZ51367.1 - 2.7e-16 59.7 4.3 1.2e-06 29.1 0.3 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat TPR_1 PF00515.28 KXZ51367.1 - 0.00021 20.9 0.0 0.94 9.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ51367.1 - 0.00058 19.8 0.1 5.7 7.3 0.1 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KXZ51367.1 - 0.00067 19.9 0.4 0.11 12.8 0.0 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KXZ51368.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ51368.1 - 5.3e-05 22.2 0.0 7.7e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ51368.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase MAD PF05557.13 KXZ51369.1 - 0.0028 16.1 11.0 0.003 16.0 11.0 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF2968 PF11180.8 KXZ51369.1 - 0.0057 16.3 3.3 0.0067 16.1 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) ELH PF02323.15 KXZ51369.1 - 0.0072 15.7 1.0 0.0072 15.7 1.0 1.1 1 0 0 1 1 1 1 Egg-laying hormone precursor TerB PF05099.13 KXZ51369.1 - 0.02 14.9 0.7 0.024 14.6 0.7 1.0 1 0 0 1 1 1 0 Tellurite resistance protein TerB DUF4140 PF13600.6 KXZ51369.1 - 0.03 14.8 4.1 0.038 14.4 4.1 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.6 KXZ51369.1 - 0.04 14.3 14.5 0.065 13.6 14.5 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 MctB PF11382.8 KXZ51369.1 - 0.041 13.6 1.7 0.05 13.3 1.7 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF1640 PF07798.11 KXZ51369.1 - 0.084 12.9 5.5 0.092 12.8 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) JIP_LZII PF16471.5 KXZ51369.1 - 0.086 13.0 12.8 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Prefoldin_2 PF01920.20 KXZ51369.1 - 0.27 11.2 13.5 7.8 6.5 10.8 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF4337 PF14235.6 KXZ51369.1 - 1.2 9.2 3.1 1.3 9.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Atg14 PF10186.9 KXZ51369.1 - 1.3 8.1 8.0 1.4 7.9 8.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 KXZ51369.1 - 1.4 8.2 9.3 1.6 8.0 9.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 KXZ51369.1 - 1.5 7.4 7.5 1.7 7.2 7.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tho2 PF11262.8 KXZ51369.1 - 4.4 6.4 6.9 5.3 6.2 6.9 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 YabA PF06156.13 KXZ51369.1 - 5.3 7.7 9.5 12 6.6 9.5 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Spc24 PF08286.11 KXZ51369.1 - 5.6 7.3 10.3 23 5.3 0.1 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 KXZ51369.1 - 7.2 7.1 18.1 16 6.1 18.1 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Lipoxygenase PF00305.19 KXZ51371.1 - 1e-140 470.3 0.0 2.7e-117 392.9 0.0 2.0 2 0 0 2 2 2 2 Lipoxygenase Dicistro_VP4 PF11492.8 KXZ51371.1 - 0.35 10.9 1.8 0.51 10.3 0.3 2.0 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 CbiQ PF02361.16 KXZ51372.1 - 6.1e-22 78.3 0.6 8.4e-22 77.9 0.6 1.3 1 0 0 1 1 1 1 Cobalt transport protein RSN1_7TM PF02714.15 KXZ51373.1 - 0.00058 19.3 2.2 0.00064 19.1 0.4 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate TMC PF07810.13 KXZ51373.1 - 0.045 14.3 0.0 0.083 13.5 0.0 1.4 1 0 0 1 1 1 0 TMC domain EF-hand_1 PF00036.32 KXZ51375.1 - 2.5e-20 70.5 1.2 8.1e-06 25.0 0.1 3.5 2 1 1 3 3 3 3 EF hand EF-hand_5 PF13202.6 KXZ51375.1 - 2.7e-16 58.2 1.7 5.1e-05 22.6 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KXZ51375.1 - 1.7e-15 57.2 2.8 2.7e-10 40.5 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ51375.1 - 5.8e-14 50.8 9.3 1.9e-05 24.2 0.2 3.8 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KXZ51375.1 - 5.9e-06 26.0 12.1 0.01 15.7 0.3 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KXZ51375.1 - 0.00095 19.4 0.0 1.6 9.1 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KXZ51375.1 - 0.036 14.4 0.1 2.3 8.6 0.0 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Meth_synt_1 PF08267.12 KXZ51375.1 - 0.052 13.1 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain UCH PF00443.29 KXZ51376.1 - 0.0017 17.9 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ51376.1 - 0.0044 16.7 0.0 0.0059 16.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nudix_N_2 PF14803.6 KXZ51376.1 - 0.28 11.2 1.8 7.7 6.5 0.0 3.0 3 0 0 3 3 3 0 Nudix N-terminal Rod_cone_degen PF15201.6 KXZ51376.1 - 2.5 8.3 4.6 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Progressive rod-cone degeneration CHRD PF07452.12 KXZ51377.1 - 1.6e-14 54.8 0.0 1.9e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 CHRD domain AAA PF00004.29 KXZ51379.1 - 4.1e-19 69.3 0.0 3.4e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ51379.1 - 2e-07 31.1 0.0 8.4e-07 29.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ51379.1 - 2.3e-05 24.8 0.1 0.00031 21.2 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXZ51379.1 - 4.4e-05 24.0 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXZ51379.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXZ51379.1 - 0.0016 17.7 0.0 0.0038 16.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXZ51379.1 - 0.0025 17.3 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KXZ51379.1 - 0.0038 17.5 0.0 0.0079 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KXZ51379.1 - 0.0042 17.0 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KXZ51379.1 - 0.0054 17.1 0.0 0.028 14.8 0.0 2.2 2 0 0 2 2 2 1 RNA helicase Secretin_N_2 PF07655.13 KXZ51379.1 - 0.0096 16.4 1.5 0.0096 16.4 1.5 2.5 2 0 0 2 2 2 1 Secretin N-terminal domain RuvB_N PF05496.12 KXZ51379.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KXZ51379.1 - 0.02 14.6 0.1 0.036 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXZ51379.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KXZ51379.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXZ51379.1 - 0.031 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ51379.1 - 0.036 14.0 0.1 0.1 12.5 0.1 1.8 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 KXZ51379.1 - 0.036 14.4 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 KXZ51379.1 - 0.091 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase ABC_tran PF00005.27 KXZ51379.1 - 0.092 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KXZ51379.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 KXZ51379.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 KXZ51379.1 - 0.16 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region MRI PF15325.6 KXZ51379.1 - 8.9 7.5 6.6 4.6 8.4 1.3 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection RINGv PF12906.7 KXZ51380.1 - 1.1e-06 28.6 6.1 2.2e-06 27.7 6.1 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXZ51380.1 - 0.1 13.0 7.4 0.27 11.6 7.4 1.7 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.29 KXZ51380.1 - 3.2 7.7 5.5 8.7 6.3 5.3 1.8 1 1 0 1 1 1 0 PHD-finger SIR2 PF02146.17 KXZ51382.1 - 3.1e-19 69.6 0.3 3.1e-19 69.6 0.3 2.3 2 0 0 2 2 2 1 Sir2 family AAA PF00004.29 KXZ51383.1 - 3.2e-19 69.7 0.0 2.4e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ51383.1 - 5.8e-07 29.6 0.0 1.7e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXZ51383.1 - 6.8e-05 23.4 0.0 0.00018 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ51383.1 - 9.4e-05 22.8 0.1 0.00036 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KXZ51383.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXZ51383.1 - 0.0018 17.5 0.0 0.0044 16.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXZ51383.1 - 0.0025 17.3 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KXZ51383.1 - 0.0027 18.0 0.0 0.0095 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXZ51383.1 - 0.0083 16.5 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_21 PF13304.6 KXZ51383.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KXZ51383.1 - 0.012 15.3 0.3 0.037 13.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXZ51383.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 KXZ51383.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXZ51383.1 - 0.022 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXZ51383.1 - 0.026 14.3 0.3 0.051 13.3 0.3 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ51383.1 - 0.032 14.8 0.2 0.08 13.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KXZ51383.1 - 0.044 14.1 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ51383.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 NACHT domain TsaE PF02367.17 KXZ51383.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 KXZ51383.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Ribosomal_L30 PF00327.20 KXZ51384.1 - 1.4e-16 60.1 0.0 2.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DEC-1_N PF04625.13 KXZ51384.1 - 0.31 10.0 4.7 0.35 9.8 4.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-C3HC4 PF00097.25 KXZ51385.1 - 0.15 11.9 4.2 0.67 9.9 4.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ51385.1 - 0.21 11.5 5.5 0.39 10.6 5.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXZ51385.1 - 0.23 11.5 4.3 0.87 9.7 4.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger MecA PF05389.12 KXZ51385.1 - 0.45 10.1 14.1 0.77 9.3 3.7 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) zf-RING_5 PF14634.6 KXZ51385.1 - 3.6 7.6 8.4 9.7 6.3 8.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Ndc1_Nup PF09531.10 KXZ51385.1 - 7.3 5.2 32.0 10 4.7 32.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 KXZ51385.1 - 7.5 4.5 22.6 9.7 4.2 22.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Guanylate_cyc PF00211.20 KXZ51386.1 - 5.4e-57 192.4 0.1 7.4e-57 191.9 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KXZ51386.1 - 8.6e-45 152.9 0.5 8.5e-29 100.6 0.2 2.2 1 1 1 2 2 2 2 Heme NO binding associated HNOB PF07700.15 KXZ51386.1 - 4.9e-21 75.4 0.0 7.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding DUF3872 PF12988.7 KXZ51386.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) IQ PF00612.27 KXZ51388.1 - 0.0085 15.8 0.4 0.025 14.3 0.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cpn60_TCP1 PF00118.24 KXZ51389.1 - 3.5e-155 517.4 13.1 4e-155 517.2 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_CP76 PF06892.11 KXZ51389.1 - 0.091 12.3 0.1 2 7.9 0.0 2.4 1 1 1 2 2 2 0 Phage regulatory protein CII (CP76) Ribosomal_S7 PF00177.21 KXZ51390.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RED_N PF07808.13 KXZ51390.1 - 0.1 12.2 1.6 0.12 11.9 1.6 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Hint PF01079.20 KXZ51391.1 - 1.6e-23 83.4 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Hint module E2F_TDP PF02319.20 KXZ51392.1 - 0.0085 16.1 0.3 0.048 13.7 0.1 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain EMC3_TMCO1 PF01956.16 KXZ51392.1 - 0.049 13.4 0.4 0.069 12.9 0.3 1.3 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4006 PF13179.6 KXZ51392.1 - 0.14 12.1 0.6 0.24 11.3 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) rve PF00665.26 KXZ51393.1 - 9.9e-10 38.7 0.0 1.8e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KXZ51393.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Hint PF01079.20 KXZ51394.1 - 4.4e-24 85.2 0.0 7.2e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Hint module Intein_splicing PF14890.6 KXZ51394.1 - 0.045 13.7 0.0 0.22 11.4 0.0 2.0 1 1 0 1 1 1 0 Intein splicing domain RVT_1 PF00078.27 KXZ51395.1 - 0.00016 21.2 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hint PF01079.20 KXZ51396.1 - 1.3e-24 86.9 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Hint module Intein_splicing PF14890.6 KXZ51396.1 - 0.011 15.7 0.0 0.069 13.1 0.0 2.1 1 1 0 1 1 1 0 Intein splicing domain Ank_4 PF13637.6 KXZ51398.1 - 0.016 15.8 0.1 0.71 10.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51398.1 - 0.099 13.2 1.8 11 7.0 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat GATase_6 PF13522.6 KXZ51400.1 - 3.4e-15 56.4 0.0 2.7e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXZ51400.1 - 3.2e-13 49.7 0.0 8.1e-13 48.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXZ51400.1 - 0.0037 16.2 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 KXZ51400.1 - 0.0039 16.7 0.0 0.0097 15.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ribosomal_S8 PF00410.19 KXZ51401.1 - 3.9e-21 75.3 0.0 5.3e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glycolytic PF00274.19 KXZ51402.1 - 5.7e-160 531.8 0.0 6.5e-160 531.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I WD40 PF00400.32 KXZ51403.1 - 2e-08 34.7 8.0 0.072 14.0 0.4 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat FAM176 PF14851.6 KXZ51403.1 - 0.13 11.9 3.2 0.23 11.1 3.2 1.3 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 KXZ51403.1 - 1.3 9.0 5.8 2.3 8.2 5.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.10 KXZ51403.1 - 3 7.1 12.2 4.1 6.7 12.2 1.1 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.6 KXZ51403.1 - 6.3 7.3 11.1 15 6.0 11.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KXZ51403.1 - 8.6 5.6 21.5 14 4.9 21.5 1.2 1 0 0 1 1 1 0 NOA36 protein PDZ PF00595.24 KXZ51404.1 - 0.00013 22.2 0.1 0.00025 21.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ51404.1 - 0.00068 19.9 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KXZ51404.1 - 0.043 13.7 0.2 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 PDZ domain UPF0225 PF17775.1 KXZ51405.1 - 2.3e-22 79.7 0.0 2.9e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 KXZ51405.1 - 0.085 12.8 9.6 0.14 12.1 9.6 1.3 1 0 0 1 1 1 0 SEC-C motif zf-MYND PF01753.18 KXZ51407.1 - 0.00016 21.7 9.2 0.00016 21.7 9.2 1.9 2 0 0 2 2 2 1 MYND finger DNA_pol_A_exo1 PF01612.20 KXZ51408.1 - 2.1e-10 40.6 0.0 2.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Beta_helix PF13229.6 KXZ51409.1 - 2.9e-12 46.7 0.0 1.7e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KXZ51409.1 - 0.00072 18.9 0.0 0.07 12.4 0.0 2.1 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KXZ51409.1 - 0.0013 18.1 0.0 0.019 14.3 0.0 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) Tho2 PF11262.8 KXZ51410.1 - 2.3e-63 214.2 0.0 2.3e-63 214.2 0.0 2.8 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 KXZ51410.1 - 6.7e-57 193.5 0.0 6.4e-27 94.5 0.0 4.3 3 1 1 4 4 4 3 THO complex subunit 2 N-terminus Thoc2 PF11732.8 KXZ51410.1 - 2.7e-23 81.8 0.1 1.4e-21 76.3 0.0 2.6 2 0 0 2 2 2 1 Transcription- and export-related complex subunit PAM2 PF07145.15 KXZ51410.1 - 0.022 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region EF-hand_5 PF13202.6 KXZ51411.1 - 6.3e-05 22.3 0.7 0.00014 21.2 0.7 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ51411.1 - 0.00013 21.3 0.3 0.00029 20.2 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ51411.1 - 0.00018 21.9 0.0 0.00037 20.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ51411.1 - 0.0094 15.8 0.1 0.028 14.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXZ51411.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF2597 PF10772.9 KXZ51411.1 - 0.059 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) PBP_N PF17093.5 KXZ51411.1 - 0.069 13.4 1.1 1.5 9.1 0.4 2.3 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus VOMI PF03762.17 KXZ51412.1 - 1.3e-22 80.7 4.4 8.5e-22 78.1 4.4 1.9 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) EF-hand_7 PF13499.6 KXZ51413.1 - 8.5e-05 22.9 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ51413.1 - 0.00013 21.2 0.3 0.00021 20.6 0.3 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ51413.1 - 0.0007 19.4 0.2 0.0022 17.8 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ51413.1 - 0.00098 18.5 0.7 0.0017 17.8 0.7 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ51413.1 - 0.0037 17.1 0.1 0.007 16.2 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain PBP_N PF17093.5 KXZ51413.1 - 0.0087 16.3 0.1 0.011 16.0 0.1 1.1 1 0 0 1 1 1 1 Penicillin-binding protein N-terminus DUF4547 PF15080.6 KXZ51413.1 - 0.029 14.0 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) VOMI PF03762.17 KXZ51415.1 - 1.2e-22 80.8 5.3 1.2e-21 77.6 5.4 1.9 1 1 1 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) Peptidase_M11 PF05548.11 KXZ51416.1 - 4.2e-19 68.8 0.1 3.5e-12 46.1 0.0 2.1 1 1 1 2 2 2 2 Gametolysin peptidase M11 CBM_14 PF01607.24 KXZ51418.1 - 4.6e-08 33.1 2.7 7.3e-05 22.9 0.1 5.5 6 0 0 6 6 6 3 Chitin binding Peritrophin-A domain Atg14 PF10186.9 KXZ51419.1 - 9e-06 25.0 21.1 2.8e-05 23.4 6.7 9.0 1 1 7 9 9 9 3 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KXZ51419.1 - 0.00043 20.6 218.2 0.057 13.6 13.9 11.5 1 1 10 12 12 12 6 Autophagy protein 16 (ATG16) PEARLI-4 PF05278.12 KXZ51419.1 - 0.0032 17.1 1.4 0.0032 17.1 1.4 8.9 5 3 4 10 10 10 1 Arabidopsis phospholipase-like protein (PEARLI 4) HMMR_C PF15908.5 KXZ51419.1 - 0.01 16.1 1.8 0.01 16.1 1.8 9.0 7 3 1 9 9 9 0 Hyaluronan mediated motility receptor C-terminal TMF_DNA_bd PF12329.8 KXZ51419.1 - 0.019 15.0 0.9 0.019 15.0 0.9 15.6 5 3 8 17 17 17 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KXZ51419.1 - 0.023 14.8 0.4 0.023 14.8 0.4 11.1 1 1 8 11 11 11 0 Uncharacterised protein family (UPF0242) N-terminus SHIPPO-rpt PF07004.12 KXZ51419.1 - 0.16 13.0 0.1 0.35 11.8 0.1 1.6 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat Fez1 PF06818.15 KXZ51419.1 - 2 8.8 162.0 0.26 11.7 12.5 9.5 1 1 7 8 8 8 0 Fez1 Csa1 PF06023.12 KXZ51419.1 - 3.1 7.1 6.2 0.74 9.1 0.3 3.0 2 0 0 2 2 2 0 CRISPR-associated exonuclease Csa1 Pkinase_Tyr PF07714.17 KXZ51422.1 - 7.1e-32 110.7 0.0 2.9e-14 53.0 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ51422.1 - 2.9e-29 102.2 0.0 9.8e-20 71.0 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain APH PF01636.23 KXZ51422.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Lipase_3 PF01764.25 KXZ51423.1 - 8.5e-21 74.3 0.0 2.8e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) TFIIS_C PF01096.18 KXZ51424.1 - 1.2e-19 69.8 4.3 1.2e-19 69.8 4.3 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 KXZ51424.1 - 0.00026 20.6 0.9 0.00061 19.4 0.9 1.7 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.7 KXZ51424.1 - 0.0063 16.5 1.5 0.0063 16.5 1.5 2.3 2 1 0 2 2 2 1 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.16 KXZ51424.1 - 0.011 15.6 4.6 0.42 10.5 0.1 3.0 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-Dof PF02701.15 KXZ51424.1 - 0.022 14.9 4.6 1.3 9.2 1.8 2.2 2 0 0 2 2 2 0 Dof domain, zinc finger zinc_ribbon_10 PF10058.9 KXZ51424.1 - 0.038 13.7 5.0 0.31 10.8 0.6 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ADK_lid PF05191.14 KXZ51424.1 - 0.049 13.6 0.3 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid EGL-1 PF11430.8 KXZ51424.1 - 0.12 12.2 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 Rubredoxin PF00301.20 KXZ51424.1 - 0.14 12.2 5.3 2.4 8.3 0.3 2.9 3 0 0 3 3 3 0 Rubredoxin Tnp_zf-ribbon_2 PF13842.6 KXZ51424.1 - 0.16 12.8 5.5 1.5 9.7 0.1 3.0 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon zinc_ribbon_4 PF13717.6 KXZ51424.1 - 0.24 11.3 8.2 13 5.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DHQS PF01959.16 KXZ51425.1 - 2.9e-89 299.5 0.0 1.8e-80 270.5 0.0 2.0 2 0 0 2 2 2 2 3-dehydroquinate synthase II TnsE_C PF18623.1 KXZ51425.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 TnsE C-terminal domain TNT PF14021.6 KXZ51425.1 - 0.068 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin Proteasome PF00227.26 KXZ51425.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit Methyltr_RsmB-F PF01189.17 KXZ51425.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F eIF-1a PF01176.19 KXZ51425.1 - 0.18 11.6 0.0 0.72 9.7 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Nramp PF01566.18 KXZ51426.1 - 6.3e-105 351.1 13.3 9e-105 350.5 13.3 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Thioredoxin PF00085.20 KXZ51427.1 - 3e-11 43.2 0.0 3.3e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KXZ51427.1 - 0.049 13.4 0.0 0.087 12.6 0.0 1.4 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 KXZ51427.1 - 0.12 12.9 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Phosducin PF02114.16 KXZ51427.1 - 0.18 10.7 0.0 0.2 10.6 0.0 1.0 1 0 0 1 1 1 0 Phosducin zinc_ribbon_6 PF14599.6 KXZ51428.1 - 2.9e-22 78.4 0.1 2.9e-22 78.4 0.1 3.3 2 0 0 2 2 2 1 Zinc-ribbon Hemerythrin PF01814.23 KXZ51428.1 - 3.5e-19 69.7 35.7 2.3e-08 34.7 1.1 5.3 4 2 0 4 4 4 3 Hemerythrin HHE cation binding domain zf-CHY PF05495.12 KXZ51428.1 - 5.1e-19 68.5 23.6 5.1e-19 68.5 23.6 4.1 3 0 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KXZ51428.1 - 5e-08 33.2 9.5 5e-08 33.2 9.5 5.2 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ51428.1 - 0.00011 22.0 7.6 0.00011 22.0 7.6 3.9 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ51428.1 - 0.00051 20.0 10.2 0.00051 20.0 10.2 5.5 3 1 1 4 4 4 1 zinc-RING finger domain DUF2935 PF11155.8 KXZ51428.1 - 0.63 10.4 3.0 9.5 6.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) 7TMR-HDED PF07697.11 KXZ51428.1 - 5.1 7.1 8.7 2.7 8.0 1.7 3.0 2 1 0 2 2 2 0 7TM-HD extracellular HMA PF00403.26 KXZ51429.1 - 1.6e-12 47.6 0.4 2e-12 47.4 0.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Germane PF10646.9 KXZ51429.1 - 0.09 13.6 0.1 0.18 12.6 0.1 1.4 1 1 0 1 1 1 0 Sporulation and spore germination DUF4614 PF15391.6 KXZ51431.1 - 0.017 15.1 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ribonuc_L-PSP PF01042.21 KXZ51431.1 - 0.064 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP UQ_con PF00179.26 KXZ51432.1 - 9.3e-15 54.5 0.0 1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXZ51432.1 - 0.055 13.8 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain GST_N_3 PF13417.6 KXZ51433.1 - 4.2e-09 36.7 0.0 8.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXZ51433.1 - 2.6e-06 27.6 0.0 5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXZ51433.1 - 1.3e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ51433.1 - 0.03 14.3 0.1 0.065 13.3 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXZ51433.1 - 0.077 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_C1 PF00112.23 KXZ51435.1 - 8.7e-71 238.5 4.1 1.1e-70 238.1 4.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Granulin PF00396.18 KXZ51435.1 - 7.3e-07 29.4 20.0 7.3e-07 29.4 20.0 2.9 2 1 1 3 3 3 1 Granulin Inhibitor_I29 PF08246.12 KXZ51435.1 - 0.00011 22.5 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KXZ51435.1 - 0.00017 20.5 1.2 0.054 12.3 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family NUDIX PF00293.28 KXZ51436.1 - 3.3e-12 46.6 0.1 5.1e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 KXZ51436.1 - 3.4e-07 30.5 2.7 6.2e-07 29.6 2.7 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding F5_F8_type_C PF00754.25 KXZ51438.1 - 1.4e-05 25.2 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 KXZ51438.1 - 0.007 16.4 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal 2Fe-2S_thioredx PF01257.19 KXZ51439.1 - 1.4e-55 187.1 0.0 1.8e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF4817 PF16087.5 KXZ51440.1 - 0.1 12.4 0.4 0.25 11.2 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) CBM_20 PF00686.19 KXZ51441.1 - 1.3e-12 47.4 0.7 6e-12 45.3 0.3 2.0 1 1 1 2 2 2 1 Starch binding domain Baculo_PEP_C PF04513.12 KXZ51441.1 - 0.0016 18.5 2.1 0.0027 17.8 2.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CAP_N PF01213.19 KXZ51441.1 - 2.2 7.7 12.1 0.057 12.9 3.6 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KXZ51441.1 - 3.5 7.7 8.1 7.1 6.7 8.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PaO PF08417.12 KXZ51442.1 - 1.9e-15 56.7 0.0 3.1e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Pheophorbide a oxygenase DUF983 PF06170.12 KXZ51442.1 - 0.0093 16.4 0.8 0.0093 16.4 0.8 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF983) DUF677 PF05055.12 KXZ51442.1 - 0.2 10.5 4.0 0.29 10.0 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Pkinase_Tyr PF07714.17 KXZ51443.1 - 4.4e-17 62.2 0.0 6.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ51443.1 - 2.5e-13 50.0 0.0 3.6e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Hist_deacetyl PF00850.19 KXZ51444.1 - 7.4e-27 94.6 2.4 1.9e-18 67.0 0.0 2.0 2 0 0 2 2 2 2 Histone deacetylase domain Pyridoxal_deC PF00282.19 KXZ51445.1 - 5.7e-19 68.1 0.0 1.2e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXZ51445.1 - 1.1e-07 31.2 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXZ51445.1 - 0.066 11.7 0.1 0.13 10.7 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme URO-D PF01208.17 KXZ51446.1 - 0.012 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) CLASP_N PF12348.8 KXZ51447.1 - 6.4e-44 150.2 0.2 1.7e-30 106.3 0.0 4.4 4 1 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 KXZ51447.1 - 9.6e-06 25.4 21.3 0.53 10.7 0.1 9.1 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 KXZ51447.1 - 8.9e-05 22.8 18.7 0.0063 16.9 0.1 6.8 6 2 1 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KXZ51447.1 - 0.0019 18.2 0.8 4.9 7.2 0.0 4.7 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXZ51447.1 - 0.0028 18.1 20.4 0.082 13.4 0.7 7.1 6 1 1 7 7 7 2 HEAT-like repeat RIX1 PF08167.12 KXZ51447.1 - 0.015 15.0 0.8 21 4.8 0.0 4.1 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis MMS19_N PF14500.6 KXZ51447.1 - 0.016 14.8 3.6 0.27 10.8 0.0 4.2 5 1 1 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.9 KXZ51447.1 - 0.092 11.2 0.3 0.82 8.1 0.1 1.9 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit NUC173 PF08161.12 KXZ51447.1 - 0.31 10.7 1.3 4.7 6.8 0.0 3.2 3 1 1 4 4 4 0 NUC173 domain Mon1 PF03164.14 KXZ51448.1 - 8.8e-84 281.9 0.0 1.1e-83 281.5 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-MYND PF01753.18 KXZ51449.1 - 1.7e-06 28.0 7.1 3.3e-06 27.1 7.1 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KXZ51449.1 - 0.42 10.7 1.7 0.78 9.9 1.7 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PBP_like_2 PF12849.7 KXZ51449.1 - 0.46 10.1 2.2 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 PBP superfamily domain Fez1 PF06818.15 KXZ51452.1 - 0.0071 16.8 67.5 0.25 11.8 11.2 4.4 1 1 3 4 4 4 3 Fez1 DUF4201 PF13870.6 KXZ51452.1 - 1.3 8.7 34.9 4.2 7.1 14.6 5.6 3 2 1 4 4 4 0 Domain of unknown function (DUF4201) PepX_C PF08530.10 KXZ51453.1 - 0.021 14.8 0.0 0.17 11.8 0.0 2.2 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain P5CR_dimer PF14748.6 KXZ51454.1 - 1.5e-41 140.8 3.9 1.5e-41 140.8 3.9 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXZ51454.1 - 1.3e-20 73.7 0.3 7.7e-20 71.3 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXZ51454.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KXZ51454.1 - 1.3e-07 32.0 0.0 3.2e-07 30.6 0.0 1.8 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 KXZ51454.1 - 0.00073 18.6 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KXZ51454.1 - 0.002 18.1 0.1 0.028 14.4 0.1 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KXZ51454.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KXZ51454.1 - 0.016 16.0 0.0 0.033 15.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 KXZ51454.1 - 0.062 13.8 0.8 0.28 11.7 0.1 2.2 2 1 0 2 2 2 0 CoA binding domain DUF3489 PF11994.8 KXZ51454.1 - 0.086 12.9 0.1 21 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) Dimer_Tnp_hAT PF05699.14 KXZ51455.1 - 0.00064 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TPM_phosphatase PF04536.14 KXZ51457.1 - 0.0012 19.0 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 TPM domain Cyd_oper_YbgE PF09600.10 KXZ51457.1 - 0.011 16.1 0.6 0.021 15.2 0.6 1.4 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Septin PF00735.18 KXZ51458.1 - 8.6e-07 28.5 0.0 2e-05 24.0 0.0 2.0 2 0 0 2 2 2 2 Septin DUF3040 PF11239.8 KXZ51458.1 - 1.6 9.0 11.3 3.8 7.8 10.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Septin PF00735.18 KXZ51459.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Septin T2SSE PF00437.20 KXZ51459.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein WD40 PF00400.32 KXZ51460.1 - 5.3e-90 292.9 37.7 3.4e-09 37.2 0.1 14.6 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51460.1 - 9.2e-41 138.1 5.3 0.00014 22.1 0.0 12.6 2 2 12 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ51460.1 - 1.1e-18 67.8 0.0 5.9e-05 23.0 0.0 5.7 2 2 3 6 6 6 5 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXZ51460.1 - 3.9e-12 45.8 0.2 0.12 11.3 0.0 7.8 3 2 5 9 9 9 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXZ51460.1 - 2e-07 29.4 0.6 0.076 11.0 0.0 5.5 4 1 2 6 6 6 3 IKI3 family Nup160 PF11715.8 KXZ51460.1 - 1.2e-06 27.4 4.4 0.018 13.7 0.2 4.5 4 1 1 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 KXZ51460.1 - 7.8e-06 25.7 2.0 14 5.7 0.1 7.2 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KXZ51460.1 - 0.003 16.9 3.4 28 3.9 0.0 5.3 4 1 1 6 6 6 0 Neuroblastoma-amplified sequence, N terminal Kelch_2 PF07646.15 KXZ51460.1 - 0.038 14.0 0.2 0.69 10.0 0.1 3.2 2 0 0 2 2 2 0 Kelch motif DPPIV_N PF00930.21 KXZ51460.1 - 0.066 12.0 0.0 6.7 5.4 0.0 3.3 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Me-amine-dh_H PF06433.11 KXZ51460.1 - 0.092 11.6 0.0 0.22 10.3 0.0 1.6 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) APAF1_C PF17908.1 KXZ51460.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 APAF-1 helical domain DUF2510 PF10708.9 KXZ51460.1 - 0.55 10.0 0.0 0.55 10.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2510) RVT_1 PF00078.27 KXZ51461.1 - 7.1e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAD_kinase PF01513.21 KXZ51462.1 - 7.2e-46 156.7 0.0 2e-45 155.2 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase DUF3197 PF11432.8 KXZ51462.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) PP-binding PF00550.25 KXZ51464.1 - 2.4e-13 50.2 0.6 3.1e-13 49.9 0.6 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXZ51464.1 - 9.1e-08 32.2 0.9 1.5e-07 31.5 0.8 1.5 1 1 0 1 1 1 1 Acyl-carrier Glyco_hydro_9 PF00759.19 KXZ51466.1 - 4e-99 332.8 14.0 5.2e-99 332.5 14.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KXZ51468.1 - 8e-193 641.5 30.3 2.2e-102 343.5 13.8 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 PilX PF13681.6 KXZ51468.1 - 0.0021 18.4 1.0 4.4 7.8 0.1 3.2 2 0 0 2 2 2 2 Type IV pilus assembly protein PilX C-term DotA PF11388.8 KXZ51468.1 - 0.016 15.4 0.9 23 5.3 0.0 3.3 3 0 0 3 3 3 0 Phagosome trafficking protein DotA Trypan_PARP PF05887.11 KXZ51468.1 - 0.073 13.1 9.1 0.21 11.6 9.1 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NADH-G_4Fe-4S_3 PF10588.9 KXZ51468.1 - 0.33 10.5 2.1 1.2 8.8 2.1 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region GCP_C_terminal PF04130.13 KXZ51469.1 - 7.5e-24 84.7 0.0 6.5e-23 81.7 0.0 2.0 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal TFIIA PF03153.13 KXZ51469.1 - 3.6 7.5 6.1 6.1 6.7 6.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M43 PF05572.13 KXZ51471.1 - 0.00064 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXZ51471.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Ank_5 PF13857.6 KXZ51473.1 - 7.9e-11 42.0 3.4 9.4e-08 32.2 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51473.1 - 8.4e-09 35.0 0.2 1.8e-05 24.8 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXZ51473.1 - 1e-08 35.6 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51473.1 - 1.1e-07 32.2 0.1 3.1e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51473.1 - 6.5e-07 29.5 2.3 0.00039 20.7 0.3 2.8 2 0 0 2 2 2 2 Ankyrin repeat HD_4 PF13328.6 KXZ51474.1 - 2.1e-39 134.8 0.8 3.2e-39 134.1 0.8 1.3 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 KXZ51474.1 - 3.2e-33 114.5 0.0 5.7e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD PF01966.22 KXZ51474.1 - 9.6e-05 22.6 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 HD domain Far-17a_AIG1 PF04750.14 KXZ51475.1 - 0.0001 21.7 7.5 0.00093 18.6 7.5 2.0 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein HemY_N PF07219.13 KXZ51475.1 - 0.0056 16.9 0.9 0.63 10.3 0.1 2.8 2 0 0 2 2 2 2 HemY protein N-terminus PgpA PF04608.13 KXZ51475.1 - 0.12 12.3 2.7 6.3 6.8 0.3 2.4 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A EAP30 PF04157.16 KXZ51477.1 - 6.9e-26 91.0 0.0 1.3e-25 90.1 0.0 1.3 1 1 0 1 1 1 1 EAP30/Vps36 family GTP_EFTU PF00009.27 KXZ51478.1 - 5e-21 75.1 0.0 8.8e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXZ51478.1 - 1.3e-05 25.5 1.9 2.4e-05 24.6 0.6 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ51478.1 - 0.00077 19.5 0.1 0.0033 17.5 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXZ51478.1 - 0.079 13.5 0.0 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter FlgN PF05130.12 KXZ51480.1 - 0.18 12.3 3.7 1.5 9.3 3.6 2.1 1 1 2 3 3 3 0 FlgN protein Uds1 PF15456.6 KXZ51480.1 - 0.32 11.2 2.5 0.4 10.9 0.6 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Orn_Arg_deC_N PF02784.16 KXZ51481.1 - 4.5e-79 265.3 0.0 5.9e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXZ51481.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Motilin_ghrelin PF04644.12 KXZ51482.1 - 0.3 10.9 1.5 0.56 10.1 1.5 1.4 1 0 0 1 1 1 0 Motilin/ghrelin GST_C PF00043.25 KXZ51485.1 - 6.6e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ51485.1 - 0.00042 20.3 0.0 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXZ51485.1 - 0.0035 17.5 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 KXZ51487.1 - 0.00019 22.2 8.0 0.05 14.5 0.0 5.7 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51487.1 - 0.027 14.8 0.0 1.3 9.3 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ51488.1 - 3.1e-14 53.1 12.4 0.00012 22.8 0.9 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51488.1 - 1.3e-08 35.0 0.1 3.6 7.9 0.0 4.3 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ51488.1 - 0.3 10.0 0.5 26 3.6 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXZ51488.1 - 0.33 11.0 1.4 6.3 6.9 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat GCV_H PF01597.19 KXZ51489.1 - 0.027 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein GRP PF07172.11 KXZ51489.1 - 1.4 9.7 20.5 2 9.2 16.1 2.2 2 0 0 2 2 2 0 Glycine rich protein family SBP PF03110.14 KXZ51490.1 - 8.5e-24 83.7 13.3 8.5e-24 83.7 13.3 2.8 3 0 0 3 3 3 1 SBP domain Ank_3 PF13606.6 KXZ51490.1 - 0.0072 16.7 0.0 0.031 14.8 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat IncD PF17628.2 KXZ51491.1 - 0.15 11.8 0.6 0.44 10.3 0.3 1.9 2 0 0 2 2 2 0 Inclusion membrane protein D SBP_bac_1 PF01547.25 KXZ51492.1 - 5.9e-07 29.7 2.1 6.3e-07 29.6 0.0 2.1 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein Guanylate_cyc PF00211.20 KXZ51492.1 - 1.3e-06 28.1 0.0 7.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain SKG6 PF08693.10 KXZ51492.1 - 0.055 12.9 3.4 0.044 13.2 0.7 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Peptidase_C48 PF02902.19 KXZ51493.1 - 5.8e-12 45.9 6.8 1.4e-06 28.3 0.9 3.1 1 1 2 3 3 3 3 Ulp1 protease family, C-terminal catalytic domain Esterase PF00756.20 KXZ51495.1 - 4.2e-46 157.6 0.0 5.2e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KXZ51495.1 - 5.5e-05 22.5 0.1 0.00014 21.2 0.0 1.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KXZ51495.1 - 0.00018 21.1 0.6 0.0013 18.3 0.6 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KXZ51495.1 - 0.0051 17.4 1.5 0.0062 17.2 1.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KXZ51495.1 - 0.039 12.9 0.0 0.063 12.2 0.0 1.3 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF3718 PF12514.8 KXZ51495.1 - 0.044 13.9 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) Peptidase_S9 PF00326.21 KXZ51495.1 - 0.06 12.8 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KXZ51495.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) DEAD PF00270.29 KXZ51496.1 - 2e-22 79.8 0.0 2.4e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ51496.1 - 0.0013 18.8 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IQ PF00612.27 KXZ51497.1 - 0.00016 21.1 4.8 0.00016 21.1 4.8 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif Ish1 PF10281.9 KXZ51497.1 - 0.094 13.0 0.7 0.5 10.7 0.1 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Ammonium_transp PF00909.21 KXZ51498.1 - 3.5e-87 292.7 29.8 1.4e-78 264.3 26.9 2.1 1 1 1 2 2 2 2 Ammonium Transporter Family DUF2964 PF11177.8 KXZ51498.1 - 0.26 11.5 4.0 0.81 9.9 4.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) DUF1967 PF09269.11 KXZ51499.1 - 3.3e-21 75.0 0.0 6.1e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) GTP1_OBG PF01018.22 KXZ51499.1 - 8.6e-21 74.1 1.0 1.9e-20 73.0 1.0 1.6 1 0 0 1 1 1 1 GTP1/OBG Kelch_4 PF13418.6 KXZ51500.1 - 9.5e-21 73.6 0.6 0.0024 17.9 0.0 6.0 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ51500.1 - 4.6e-20 71.2 3.8 1.6e-05 24.7 0.0 5.7 4 2 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KXZ51500.1 - 4.3e-13 49.2 11.7 0.0016 18.7 0.0 7.0 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KXZ51500.1 - 5.9e-12 45.0 3.1 2.2e-05 24.0 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KXZ51500.1 - 3.1e-11 43.1 1.7 0.0026 18.0 0.0 5.5 4 2 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KXZ51500.1 - 5.5e-11 42.0 11.5 0.0018 18.2 0.0 5.7 4 2 1 5 5 5 3 Kelch motif RAG2 PF03089.14 KXZ51500.1 - 7.7e-05 21.8 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Recombination activating protein 2 DUF2630 PF10944.8 KXZ51500.1 - 0.38 11.3 1.2 0.69 10.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) RT_RNaseH PF17917.1 KXZ51502.1 - 9.3e-24 83.7 0.2 2.1e-23 82.6 0.1 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KXZ51502.1 - 1.6e-16 60.1 0.0 3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ51502.1 - 1.2e-15 57.7 0.0 1.6e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAD_binding_1 PF00667.20 KXZ51504.1 - 9.2e-33 113.7 0.0 1.3e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Ank_5 PF13857.6 KXZ51504.1 - 7e-16 58.1 3.9 1.2e-08 35.1 0.5 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51504.1 - 1.2e-15 57.8 0.9 7.5e-07 29.7 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51504.1 - 3e-13 50.0 0.2 0.00018 22.0 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) NAD_binding_1 PF00175.21 KXZ51504.1 - 4.8e-13 49.7 0.0 1.1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 KXZ51504.1 - 1.4e-09 38.3 0.0 3.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Ank PF00023.30 KXZ51504.1 - 4.8e-09 36.3 6.0 0.0089 16.4 0.1 5.1 4 1 1 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KXZ51504.1 - 5e-09 35.7 5.0 0.0046 17.4 0.1 5.1 6 0 0 6 6 6 2 Ankyrin repeat DUF1843 PF08898.10 KXZ51504.1 - 0.12 12.9 1.7 4.9 7.7 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) HTH_31 PF13560.6 KXZ51504.1 - 2.3 8.7 5.7 2.4 8.6 0.1 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain TFIIF_alpha PF05793.12 KXZ51505.1 - 0.41 9.2 23.1 0.51 8.9 23.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Red1 PF07964.11 KXZ51505.1 - 1.3 7.2 15.6 1.6 6.9 15.6 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Macoilin PF09726.9 KXZ51505.1 - 1.7 7.1 6.8 2.1 6.8 6.8 1.0 1 0 0 1 1 1 0 Macoilin family CytochromB561_N PF09786.9 KXZ51505.1 - 2 7.3 6.9 2.8 6.8 6.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mitofilin PF09731.9 KXZ51505.1 - 2.6 6.8 14.5 3.4 6.4 14.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Methyltransf_32 PF13679.6 KXZ51506.1 - 2.6e-22 79.5 2.3 8.2e-22 77.9 1.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ51506.1 - 9e-08 32.1 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ51506.1 - 0.0001 22.9 0.0 0.00023 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ51506.1 - 0.0081 16.9 0.0 0.021 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_60s PF00428.19 KXZ51506.1 - 7.9 7.1 9.8 4.1 8.1 1.3 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein MYEOV2 PF15004.6 KXZ51507.1 - 0.057 13.9 5.3 0.057 13.9 5.3 2.2 1 1 0 2 2 2 0 Myeloma-overexpressed-like Dynamin_N PF00350.23 KXZ51508.1 - 8.3e-29 100.8 0.0 2e-28 99.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXZ51508.1 - 3.6e-05 23.8 0.0 0.00011 22.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXZ51508.1 - 0.0011 18.5 0.0 0.0062 16.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXZ51508.1 - 0.11 12.8 1.6 4.9 7.5 0.0 3.7 3 1 0 3 3 3 0 AAA ATPase domain tRNA_synt_2f PF02092.17 KXZ51509.1 - 1.7e-174 581.7 0.0 2.1e-174 581.4 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit tRNA-synt_2e PF02091.15 KXZ51509.1 - 3.3e-128 426.8 0.0 4.3e-128 426.4 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit Aldo_ket_red PF00248.21 KXZ51511.1 - 2.2e-53 181.4 0.0 6e-53 179.9 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S2 PF00318.20 KXZ51514.1 - 2.5e-28 98.8 0.0 2.2e-13 49.9 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KXZ51514.1 - 0.085 14.2 5.9 0.16 13.3 5.9 1.4 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus DUF3159 PF11361.8 KXZ51515.1 - 0.038 13.7 6.3 0.052 13.3 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3159) DUF2085 PF09858.9 KXZ51515.1 - 1.1 9.7 6.1 0.24 11.9 2.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Chorein_N PF12624.7 KXZ51516.1 - 5.9e-22 78.0 0.2 1.7e-21 76.5 0.2 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 KXZ51516.1 - 7.1e-19 68.2 0.0 1.9e-18 66.8 0.0 1.7 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KXZ51516.1 - 3e-15 56.7 2.2 1.1e-09 38.5 0.0 2.8 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KXZ51516.1 - 3.1e-11 43.4 0.0 6.8e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal TFIIA PF03153.13 KXZ51516.1 - 0.51 10.3 15.5 0.75 9.7 8.1 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 KXZ51516.1 - 8.2 7.1 10.3 83 3.8 7.0 3.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 KXZ51518.1 - 3.5e-52 177.4 0.0 4.4e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51518.1 - 5.2e-30 104.6 0.0 8.5e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ51518.1 - 7.4e-08 31.6 0.0 1.2e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ51518.1 - 1e-06 28.3 0.0 2.9e-06 26.8 0.0 1.7 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KXZ51518.1 - 0.00021 21.3 4.9 0.00036 20.5 0.4 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ51518.1 - 0.0037 16.6 0.4 0.0068 15.8 0.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXZ51518.1 - 0.18 11.4 0.0 1 8.9 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NO_synthase PF02898.15 KXZ51519.1 - 1.1e-30 107.0 0.2 1.4e-19 70.4 0.3 2.0 1 1 1 2 2 2 2 Nitric oxide synthase, oxygenase domain NO_synthase PF02898.15 KXZ51520.1 - 4.4e-61 206.9 0.0 7e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 KXZ51520.1 - 3.3e-29 102.1 0.0 5.1e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXZ51520.1 - 1.4e-21 77.2 0.0 4.4e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin Ank_5 PF13857.6 KXZ51520.1 - 2.9e-18 65.7 4.6 4.5e-10 39.6 0.8 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) NAD_binding_1 PF00175.21 KXZ51520.1 - 3.3e-15 56.7 0.0 7.5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ank_4 PF13637.6 KXZ51520.1 - 5.3e-15 55.6 0.3 3.4e-05 24.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51520.1 - 1.3e-14 54.5 1.3 6.3e-06 26.7 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ51520.1 - 3e-11 42.5 4.1 0.00051 20.3 0.1 5.0 4 0 0 4 4 4 2 Ankyrin repeat Globin PF00042.22 KXZ51520.1 - 1.2e-10 41.9 0.0 2.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Globin Ank PF00023.30 KXZ51520.1 - 5.3e-10 39.3 7.6 0.0021 18.4 0.1 5.1 4 1 1 5 5 5 3 Ankyrin repeat Flavodoxin_5 PF12724.7 KXZ51520.1 - 0.0079 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Pkinase PF00069.25 KXZ51521.1 - 1.2e-27 97.0 0.0 3.8e-23 82.2 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51521.1 - 4.7e-23 81.8 0.0 6.5e-19 68.2 0.0 3.0 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KXZ51521.1 - 0.0073 16.3 0.1 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ51521.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1180 PF06679.12 KXZ51521.1 - 0.046 14.1 1.0 0.046 14.1 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pkinase_Tyr PF07714.17 KXZ51522.1 - 1.2e-33 116.5 0.0 5.9e-27 94.6 0.0 4.0 3 1 1 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 KXZ51522.1 - 2.8e-31 108.8 0.0 3.7e-26 92.1 0.0 3.6 3 1 1 4 4 4 2 Protein kinase domain APH PF01636.23 KXZ51522.1 - 0.0071 16.3 0.1 0.014 15.4 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ51522.1 - 0.036 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1180 PF06679.12 KXZ51522.1 - 0.068 13.6 0.6 0.15 12.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) POR_N PF01855.19 KXZ51522.1 - 0.46 10.2 2.5 0.39 10.4 0.7 1.7 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Pkinase PF00069.25 KXZ51523.1 - 2.9e-23 82.6 0.0 2e-22 79.8 0.0 2.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51523.1 - 2.4e-18 66.4 0.0 5.2e-16 58.7 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ51523.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ51523.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ51524.1 - 8e-30 104.0 0.0 7.7e-27 94.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ51524.1 - 2.4e-28 99.3 0.0 2.3e-26 92.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ51524.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ51524.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Toluene_X PF03349.16 KXZ51524.1 - 0.074 11.6 0.6 0.11 11.0 0.6 1.2 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) DUF1180 PF06679.12 KXZ51524.1 - 1.3 9.5 3.9 0.32 11.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF5068 PF16781.5 KXZ51525.1 - 0.095 12.5 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) DUF3251 PF11622.8 KXZ51525.1 - 0.096 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Phage_integrase PF00589.22 KXZ51526.1 - 0.00062 19.6 0.0 0.00078 19.3 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Pkinase_Tyr PF07714.17 KXZ51527.1 - 3.1e-38 131.5 0.0 3e-35 121.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ51527.1 - 9.9e-38 130.0 0.0 1e-35 123.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KXZ51527.1 - 0.0061 16.5 0.3 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3294 PF07957.11 KXZ51528.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) Pkinase PF00069.25 KXZ51530.1 - 2.5e-29 102.4 0.0 3.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51530.1 - 3.6e-27 95.3 0.0 4.8e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ51530.1 - 0.0011 19.0 3.6 0.0057 16.6 1.3 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF3294 PF07957.11 KXZ51531.1 - 0.038 13.7 0.0 0.078 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) Pkinase_Tyr PF07714.17 KXZ51532.1 - 0.23 10.7 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase GRDP-like PF07173.12 KXZ51533.1 - 1.5e-11 45.1 0.0 2.8e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like RabGAP-TBC PF00566.18 KXZ51534.1 - 6.3e-46 156.7 0.0 9.7e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YqjK PF13997.6 KXZ51534.1 - 0.033 14.4 0.9 8.5 6.7 0.4 2.7 2 0 0 2 2 2 0 YqjK-like protein MDFI PF15316.6 KXZ51535.1 - 1.5 8.9 9.0 1.9 8.5 9.0 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Ribosomal_L23 PF00276.20 KXZ51536.1 - 2.3e-13 50.3 0.0 3.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 ABC_tran PF00005.27 KXZ51537.1 - 2.5e-30 105.8 0.0 4.4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXZ51537.1 - 5.1e-06 26.1 0.5 0.00063 19.2 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXZ51537.1 - 0.0001 22.3 0.1 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXZ51537.1 - 0.00039 20.7 0.2 0.0066 16.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXZ51537.1 - 0.00064 20.0 0.5 1.3 9.3 0.2 2.6 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.6 KXZ51537.1 - 0.0015 18.3 0.3 0.0052 16.5 0.3 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ51537.1 - 0.0032 17.9 0.7 0.0032 17.9 0.7 2.5 2 1 0 2 2 2 1 AAA ATPase domain ABC_membrane PF00664.23 KXZ51537.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_5 PF07728.14 KXZ51537.1 - 0.015 15.3 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KXZ51537.1 - 0.071 13.4 0.6 0.071 13.4 0.6 3.2 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KXZ51537.1 - 0.078 13.1 0.3 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain DEAD PF00270.29 KXZ51538.1 - 3.3e-50 170.3 0.0 1.2e-49 168.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ51538.1 - 3.2e-28 98.3 0.0 6.9e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 KXZ51538.1 - 6.8e-06 26.3 0.0 1.9e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 KXZ51538.1 - 3.6e-05 23.8 0.0 5.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KXZ51538.1 - 0.0049 16.2 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 SecA DEAD-like domain CMS1 PF14617.6 KXZ51538.1 - 0.0051 16.2 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KXZ51538.1 - 0.059 12.6 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DUF4795 PF16043.5 KXZ51538.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Endosulfine PF04667.17 KXZ51539.1 - 8.7e-13 48.2 0.2 1.2e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region MPC PF03650.13 KXZ51541.1 - 1.1e-37 128.6 0.6 1.2e-37 128.5 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers WD40 PF00400.32 KXZ51543.1 - 1.9e-05 25.3 5.6 0.029 15.2 0.5 4.6 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KXZ51543.1 - 4.5e-05 23.8 18.0 0.028 14.9 1.3 4.8 3 2 1 4 4 4 2 PQQ-like domain ANAPC4_WD40 PF12894.7 KXZ51543.1 - 0.003 17.8 0.0 0.069 13.5 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXZ51543.1 - 0.004 16.8 1.1 0.019 14.6 0.1 1.9 2 0 0 2 2 2 1 PQQ-like domain CALCOCO1 PF07888.11 KXZ51544.1 - 0.0014 17.6 19.8 0.0017 17.3 19.8 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Exonuc_VII_L PF02601.15 KXZ51544.1 - 0.0028 17.3 7.9 0.0028 17.3 7.9 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit MscS_porin PF12795.7 KXZ51544.1 - 0.0035 16.9 24.7 0.014 14.9 24.7 1.9 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF745 PF05335.13 KXZ51544.1 - 0.0043 16.8 19.3 0.0066 16.2 19.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF3552 PF12072.8 KXZ51544.1 - 0.0044 16.5 16.9 0.0058 16.1 16.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) AAA_13 PF13166.6 KXZ51544.1 - 0.0058 15.3 16.4 0.021 13.5 2.6 2.0 1 1 1 2 2 2 2 AAA domain ATG16 PF08614.11 KXZ51544.1 - 0.011 16.0 23.2 0.014 15.6 22.5 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KXZ51544.1 - 0.015 14.6 18.0 0.019 14.3 18.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HemX PF04375.14 KXZ51544.1 - 0.029 13.7 17.5 0.36 10.1 17.5 1.9 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Filament PF00038.21 KXZ51544.1 - 0.032 13.8 17.5 0.042 13.4 17.5 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF812 PF05667.11 KXZ51544.1 - 0.28 10.0 16.9 0.34 9.7 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4239 PF14023.6 KXZ51544.1 - 0.36 10.5 5.8 0.43 10.3 4.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Cupin_8 PF13621.6 KXZ51544.1 - 0.37 10.5 1.8 0.43 10.2 1.8 1.1 1 0 0 1 1 1 0 Cupin-like domain V_ATPase_I PF01496.19 KXZ51544.1 - 0.52 8.2 8.4 0.59 8.0 8.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 KXZ51544.1 - 1.3 9.6 6.1 0.73 10.3 2.9 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 KXZ51544.1 - 1.5 7.9 21.8 2.9 6.9 21.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 KXZ51544.1 - 1.6 8.0 13.1 2 7.7 13.1 1.1 1 0 0 1 1 1 0 FAM76 protein FlaC_arch PF05377.11 KXZ51544.1 - 1.6 9.1 5.9 11 6.5 0.7 2.9 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) ARGLU PF15346.6 KXZ51544.1 - 1.9 8.4 25.3 4.4 7.2 25.3 1.6 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 EzrA PF06160.12 KXZ51544.1 - 2.1 6.5 19.4 2.5 6.2 3.4 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Nup88 PF10168.9 KXZ51544.1 - 3 5.6 11.8 3.7 5.3 11.8 1.1 1 0 0 1 1 1 0 Nuclear pore component AAA_23 PF13476.6 KXZ51544.1 - 3.3 8.2 14.2 4.9 7.6 14.2 1.2 1 0 0 1 1 1 0 AAA domain HSP70 PF00012.20 KXZ51544.1 - 3.4 5.7 16.4 5.7 5.0 16.1 1.4 1 1 1 2 2 2 0 Hsp70 protein Fib_alpha PF08702.10 KXZ51544.1 - 4.6 7.4 11.9 5.9 7.1 10.7 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FliD_N PF02465.18 KXZ51544.1 - 4.7 8.0 12.8 3.8 8.3 3.6 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spc7 PF08317.11 KXZ51544.1 - 4.7 6.0 24.9 31 3.3 24.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 KXZ51544.1 - 5.6 7.7 15.8 2.2 9.0 11.8 2.2 1 1 1 2 2 2 0 SlyX Fzo_mitofusin PF04799.13 KXZ51544.1 - 5.6 6.5 10.8 0.48 10.0 5.2 1.8 1 1 1 2 2 2 0 fzo-like conserved region TMPIT PF07851.13 KXZ51544.1 - 5.9 6.0 14.6 3.8 6.7 13.1 1.4 1 1 0 1 1 1 0 TMPIT-like protein BRE1 PF08647.11 KXZ51544.1 - 6.5 6.9 22.8 1.5 8.9 6.5 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 KXZ51544.1 - 6.8 6.8 27.8 1.9 8.5 7.9 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3138 PF11336.8 KXZ51544.1 - 7.1 5.1 6.4 8.5 4.9 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) APG6_N PF17675.1 KXZ51544.1 - 7.2 7.1 24.2 14 6.3 24.2 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3391 PF11871.8 KXZ51544.1 - 9.3 6.8 13.0 15 6.1 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DNA_ligase_A_N PF04675.14 KXZ51545.1 - 9.2e-29 101.0 0.0 1.2e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KXZ51545.1 - 2.6e-06 27.2 0.0 4.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Tim17 PF02466.19 KXZ51546.1 - 1.2e-12 48.1 1.2 1.8e-12 47.6 1.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family YhfZ_C PF14503.6 KXZ51548.1 - 0.23 10.9 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 YhfZ C-terminal domain PDDEXK_6 PF04720.12 KXZ51549.1 - 5e-22 78.9 0.0 9.2e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 PDDEXK-like family of unknown function LRR_6 PF13516.6 KXZ51549.1 - 3e-06 26.8 2.0 0.0071 16.3 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeat HYR PF02494.16 KXZ51550.1 - 1.7e-24 86.0 59.2 3.2e-06 27.4 0.7 9.9 8 1 1 9 9 9 7 HYR domain PAN_4 PF14295.6 KXZ51550.1 - 1.2e-17 63.6 22.5 5.4e-05 23.0 1.0 6.8 5 0 0 5 5 5 5 PAN domain RicinB_lectin_2 PF14200.6 KXZ51550.1 - 5.8e-08 33.4 0.0 0.00083 20.0 0.0 3.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like hEGF PF12661.7 KXZ51550.1 - 0.0051 17.4 89.4 0.27 11.9 0.3 13.3 12 0 0 12 12 12 7 Human growth factor-like EGF cEGF PF12662.7 KXZ51550.1 - 0.006 16.5 3.4 0.006 16.5 3.4 12.4 13 0 0 13 13 13 6 Complement Clr-like EGF-like Jacalin PF01419.17 KXZ51550.1 - 0.041 13.8 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain EGF_3 PF12947.7 KXZ51550.1 - 0.042 14.0 130.4 0.046 13.9 6.1 14.3 14 0 0 14 14 14 0 EGF domain Thaumatin PF00314.17 KXZ51553.1 - 9.5e-19 67.9 6.8 3.4e-17 62.8 2.6 2.7 1 1 1 2 2 2 2 Thaumatin family CAAD PF14159.6 KXZ51554.1 - 2.9e-21 75.1 0.1 3.7e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ETRAMP PF09716.10 KXZ51554.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HECT PF00632.25 KXZ51555.1 - 5.8e-63 213.2 0.0 9e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KXZ51555.1 - 2.5e-37 127.6 0.0 8.9e-12 45.2 0.0 5.8 5 1 0 5 5 5 4 SPRY domain PCMT PF01135.19 KXZ51555.1 - 4.3e-19 69.1 0.0 4.2e-18 65.9 0.0 2.2 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXZ51555.1 - 1.9e-06 27.8 0.1 4.5e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ51555.1 - 0.00014 22.5 0.0 0.00065 20.4 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXZ51555.1 - 0.0063 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ51555.1 - 0.096 13.4 0.1 0.39 11.4 0.1 2.1 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXZ51555.1 - 0.1 12.2 0.5 0.23 11.0 0.2 1.7 2 0 0 2 2 2 0 Methyltransferase small domain DOT1 PF08123.13 KXZ51555.1 - 0.12 11.9 0.2 0.77 9.2 0.1 2.2 3 0 0 3 3 3 0 Histone methylation protein DOT1 AAA PF00004.29 KXZ51556.1 - 1.3e-37 129.1 0.0 2.6e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ51556.1 - 2.9e-07 30.2 0.2 1.1e-06 28.3 0.2 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ51556.1 - 5.1e-06 26.5 0.2 3.9e-05 23.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXZ51556.1 - 9e-05 22.3 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ51556.1 - 0.00046 20.5 0.1 0.0064 16.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXZ51556.1 - 0.001 19.1 0.0 0.0032 17.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXZ51556.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein SH3_12 PF18129.1 KXZ51556.1 - 0.0018 18.3 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain AAA_33 PF13671.6 KXZ51556.1 - 0.0035 17.5 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXZ51556.1 - 0.0037 16.5 0.1 0.0075 15.5 0.1 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KXZ51556.1 - 0.0078 15.6 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXZ51556.1 - 0.016 15.8 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXZ51556.1 - 0.02 14.4 0.1 0.036 13.6 0.1 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KXZ51556.1 - 0.022 15.1 0.1 0.022 15.1 0.1 4.6 6 1 0 6 6 5 0 AAA ATPase domain AAA_24 PF13479.6 KXZ51556.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXZ51556.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KXZ51556.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_kin PF00625.21 KXZ51556.1 - 0.28 10.8 0.0 0.51 10.0 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase PAP_central PF04928.17 KXZ51558.1 - 9.9e-84 280.2 0.0 1.3e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KXZ51558.1 - 2.6e-13 50.0 0.0 1.7e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain Fanconi_A PF03511.14 KXZ51558.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Fanconi anaemia group A protein WD40 PF00400.32 KXZ51559.1 - 1.9e-06 28.5 4.8 0.00092 20.0 0.1 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat MTHFR PF02219.17 KXZ51560.1 - 1.5e-61 208.3 0.0 2e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RVT_2 PF07727.14 KXZ51561.1 - 1.4e-34 119.8 0.0 2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CN_hydrolase PF00795.22 KXZ51564.1 - 6e-33 114.3 0.0 8e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase XAF1_C PF18608.1 KXZ51564.1 - 0.0044 16.5 0.3 0.0099 15.4 0.3 1.5 1 0 0 1 1 1 1 XIAP-associated factor 1 C-terminal domain NAD_synthase PF02540.17 KXZ51564.1 - 0.0088 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 NAD synthase Kelch_1 PF01344.25 KXZ51564.1 - 0.044 13.4 0.3 2.5 7.7 0.2 2.7 2 0 0 2 2 2 0 Kelch motif Peptidase_M18 PF02127.15 KXZ51565.1 - 1.5e-148 495.2 0.0 1.7e-148 495.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KXZ51565.1 - 0.037 13.0 0.0 0.075 12.0 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase COX14 PF14880.6 KXZ51566.1 - 0.021 14.7 0.2 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF3098 PF11297.8 KXZ51566.1 - 0.12 12.0 0.8 9 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Pkinase PF00069.25 KXZ51567.1 - 9.9e-07 28.4 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51567.1 - 0.3 10.3 0.0 0.47 9.7 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KXZ51569.1 - 9.2e-19 67.8 0.0 2.1e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51569.1 - 1.4e-06 27.8 0.0 5.9e-06 25.8 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KXZ51569.1 - 0.0071 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GYF_2 PF14237.6 KXZ51571.1 - 5.8e-09 35.6 0.0 9.7e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 GYF domain 2 Pullulanase_N2 PF17967.1 KXZ51572.1 - 0.58 11.0 8.4 0.61 11.0 5.3 2.7 1 1 1 2 2 2 0 Pullulanase N2 domain DUF3589 PF12141.8 KXZ51573.1 - 0.00044 19.0 0.0 0.0041 15.8 0.0 2.0 2 0 0 2 2 2 2 Beta-mannosyltransferases DUF3589 PF12141.8 KXZ51574.1 - 4.6e-05 22.2 0.0 0.00054 18.7 0.0 2.1 2 0 0 2 2 2 2 Beta-mannosyltransferases Ctr PF04145.15 KXZ51575.1 - 1.5e-19 71.1 2.2 3.1e-19 70.1 2.2 1.5 1 1 0 1 1 1 1 Ctr copper transporter family zf-MYND PF01753.18 KXZ51576.1 - 5.2e-08 32.8 7.0 1.2e-07 31.7 7.0 1.6 1 0 0 1 1 1 1 MYND finger IlvC PF01450.19 KXZ51577.1 - 2.4e-42 144.6 0.2 3.4e-33 115.0 0.1 2.2 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 KXZ51577.1 - 7.5e-36 123.2 0.1 1.3e-35 122.4 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pkinase PF00069.25 KXZ51578.1 - 1.8e-36 125.9 0.0 2e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51578.1 - 4.4e-16 58.9 0.0 1.2e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ51578.1 - 0.0082 15.5 0.2 2 7.7 0.1 2.1 2 0 0 2 2 2 2 Kinase-like WD40 PF00400.32 KXZ51579.1 - 3.2e-44 148.0 45.8 0.00024 21.8 0.0 18.4 18 0 0 18 18 18 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51579.1 - 4.5e-21 74.9 9.1 0.0006 20.1 0.1 11.0 6 2 5 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXZ51579.1 - 4.5e-16 59.0 0.1 2.8e-06 26.9 0.0 5.1 4 1 1 5 5 5 3 WD40-like domain Ion_trans PF00520.31 KXZ51579.1 - 3.9e-14 52.5 19.5 5.9e-14 51.9 19.5 1.3 1 0 0 1 1 1 1 Ion transport protein PQQ_3 PF13570.6 KXZ51579.1 - 4.5e-06 27.0 3.0 0.0074 16.7 0.5 4.7 3 0 0 3 3 3 2 PQQ-like domain Frtz PF11768.8 KXZ51579.1 - 0.00034 19.1 3.7 15 3.8 0.0 5.5 5 1 1 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KXZ51579.1 - 0.00081 18.5 1.0 11 4.9 0.0 4.9 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXZ51579.1 - 0.0021 16.6 1.1 0.027 13.0 0.1 3.0 2 2 2 4 4 4 1 Cytochrome D1 heme domain PKD_channel PF08016.12 KXZ51579.1 - 0.0097 14.6 18.9 0.48 9.0 18.9 2.4 1 1 0 1 1 1 1 Polycystin cation channel CPSF_A PF03178.15 KXZ51579.1 - 0.014 14.7 2.8 0.74 9.1 0.0 3.8 3 2 1 4 4 4 0 CPSF A subunit region PD40 PF07676.12 KXZ51579.1 - 0.11 12.4 0.1 20 5.2 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Hira PF07569.11 KXZ51579.1 - 0.67 9.6 11.9 8.6 6.0 0.0 5.9 6 1 1 7 7 7 0 TUP1-like enhancer of split IKI3 PF04762.12 KXZ51579.1 - 3 5.7 7.1 2 6.3 0.1 3.5 4 0 0 4 4 4 0 IKI3 family Amidohydro_1 PF01979.20 KXZ51580.1 - 1.1e-12 48.0 0.0 3.7e-12 46.2 0.0 1.7 1 1 1 2 2 2 1 Amidohydrolase family Epimerase PF01370.21 KXZ51581.1 - 8.9e-12 45.0 0.0 3.5e-10 39.7 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXZ51581.1 - 3.3e-11 42.8 0.0 9.5e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 KXZ51581.1 - 1.1e-10 41.5 0.0 1.2e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXZ51581.1 - 7.7e-09 35.7 0.1 1.5e-08 34.7 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXZ51581.1 - 1.9e-08 33.7 0.1 2.9e-06 26.5 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXZ51581.1 - 6.1e-06 25.9 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXZ51581.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KXZ51581.1 - 0.00019 20.7 0.0 0.009 15.2 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KXZ51581.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KXZ51581.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 KR domain PapD-like PF14874.6 KXZ51582.1 - 3.9e-13 49.4 0.4 7.1e-13 48.6 0.4 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like SPESP1 PF15754.5 KXZ51582.1 - 0.86 8.7 4.0 2.2 7.4 4.0 1.6 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Spc7 PF08317.11 KXZ51582.1 - 2.7 6.8 4.5 4.7 6.0 4.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FSH1 PF03959.13 KXZ51583.1 - 8.3e-16 58.3 0.1 1.5e-14 54.2 0.1 2.0 1 1 1 2 2 2 2 Serine hydrolase (FSH1) FAD-oxidase_C PF02913.19 KXZ51584.1 - 1.1e-57 195.6 0.0 3.9e-57 193.7 0.0 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXZ51584.1 - 6.8e-35 119.8 2.7 1.4e-34 118.8 2.7 1.6 1 0 0 1 1 1 1 FAD binding domain TPR_1 PF00515.28 KXZ51584.1 - 1.4e-13 50.0 0.4 2.4e-05 23.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ51584.1 - 5.9e-11 41.6 0.2 0.00014 21.7 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ51584.1 - 1.8e-08 34.9 6.9 0.0052 17.4 0.0 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ51584.1 - 2.6e-07 30.2 0.0 0.0033 17.1 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 KXZ51584.1 - 9.3e-07 28.9 0.1 0.036 14.2 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ51584.1 - 6.9e-06 26.3 1.8 2.9e-05 24.3 1.8 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ51584.1 - 1.4e-05 25.5 0.7 0.094 13.6 0.1 4.0 2 1 1 3 3 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ51584.1 - 0.00016 21.8 0.5 0.00031 20.9 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXZ51584.1 - 0.00046 20.6 0.4 0.0054 17.2 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat UVR PF02151.19 KXZ51584.1 - 0.00046 19.8 0.6 0.001 18.7 0.6 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif TPR_8 PF13181.6 KXZ51584.1 - 0.0012 18.9 0.1 0.3 11.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ51584.1 - 0.0038 17.8 0.2 0.68 10.7 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ51584.1 - 0.016 15.2 0.1 7.9 6.6 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KXZ51584.1 - 0.049 13.5 1.4 2.2 8.3 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ51584.1 - 0.064 13.3 0.1 0.26 11.4 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat APG6 PF04111.12 KXZ51584.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Apg6 BARA domain Root_cap PF06830.11 KXZ51586.1 - 0.079 13.1 0.1 21 5.3 0.0 3.7 3 0 0 3 3 3 0 Root cap XRN_N PF03159.18 KXZ51587.1 - 9.7e-40 136.5 0.0 8.1e-19 68.0 0.0 2.5 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus Seryl_tRNA_N PF02403.22 KXZ51587.1 - 0.19 11.9 0.1 0.35 11.1 0.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KXZ51587.1 - 0.35 11.4 2.1 0.72 10.4 2.1 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 KXZ51587.1 - 2.7 8.5 7.3 13 6.3 1.3 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SAP PF02037.27 KXZ51590.1 - 0.00014 21.5 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain EGF PF00008.27 KXZ51591.1 - 1 9.7 22.1 1 9.7 3.5 3.7 3 0 0 3 3 3 0 EGF-like domain LANC_like PF05147.13 KXZ51592.1 - 1.4e-43 148.9 0.0 1.7e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 KXZ51592.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Herpes_ICP4_C PF03585.14 KXZ51593.1 - 0.1 11.3 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region zf-HC5HC2H_2 PF13832.6 KXZ51594.1 - 4.5e-27 94.4 1.7 4.5e-27 94.4 1.7 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXZ51594.1 - 1.3e-17 63.8 1.2 1.3e-17 63.8 1.2 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain SET PF00856.28 KXZ51594.1 - 1.1e-13 52.0 0.1 5.9e-13 49.6 0.1 2.3 1 1 0 1 1 1 1 SET domain FYRN PF05964.14 KXZ51594.1 - 9e-13 47.9 0.0 3.6e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 F/Y-rich N-terminus PHD_2 PF13831.6 KXZ51594.1 - 1.3e-07 31.0 8.1 1.3e-07 31.0 8.1 3.4 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 KXZ51594.1 - 2.7e-05 24.0 25.6 0.00025 20.9 11.6 2.8 2 0 0 2 2 2 2 PHD-finger FYRC PF05965.14 KXZ51594.1 - 5.2e-05 23.3 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus LBR_tudor PF09465.10 KXZ51594.1 - 0.0021 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain C1_2 PF03107.16 KXZ51594.1 - 0.0032 17.7 4.8 0.0032 17.7 4.8 3.4 3 0 0 3 3 3 1 C1 domain zf-MYND PF01753.18 KXZ51595.1 - 8.8e-06 25.7 8.8 8.8e-06 25.7 8.8 1.8 2 0 0 2 2 2 1 MYND finger BAG PF02179.16 KXZ51596.1 - 0.0016 18.8 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 BAG domain IQ PF00612.27 KXZ51596.1 - 0.22 11.4 1.7 0.73 9.8 1.7 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Cu2_monoox_C PF03712.15 KXZ51597.1 - 1.6e-23 83.0 0.1 2.7e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KXZ51597.1 - 6.3e-19 68.5 0.0 1.6e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 KXZ51597.1 - 4.4e-12 45.4 4.6 5.8e-05 22.9 0.1 4.5 4 0 0 4 4 4 2 NHL repeat SGL PF08450.12 KXZ51597.1 - 0.00031 20.4 0.1 0.0025 17.5 0.0 2.4 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KXZ51597.1 - 0.032 14.4 0.0 16 6.2 0.0 3.2 2 0 0 2 2 2 0 Two component regulator propeller Arylsulfotran_2 PF14269.6 KXZ51597.1 - 0.071 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) SDA1 PF05285.12 KXZ51597.1 - 0.75 9.2 16.2 1 8.7 16.2 1.1 1 0 0 1 1 1 0 SDA1 PvlArgDC PF01862.16 KXZ51597.1 - 3 7.6 5.0 6.1 6.6 5.0 1.4 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Nop14 PF04147.12 KXZ51597.1 - 4.5 5.3 16.9 6.1 4.9 16.9 1.0 1 0 0 1 1 1 0 Nop14-like family His_Phos_1 PF00300.22 KXZ51599.1 - 2e-06 27.6 0.9 8e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ANF_receptor PF01094.28 KXZ51599.1 - 0.0042 16.3 0.0 0.005 16.0 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region DUF1604 PF07713.13 KXZ51599.1 - 0.057 13.2 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) PAN_4 PF14295.6 KXZ51600.1 - 1 9.3 10.1 0.034 14.0 3.4 2.1 2 0 0 2 2 2 0 PAN domain Pkinase PF00069.25 KXZ51601.1 - 3.6e-55 187.2 0.0 4.9e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51601.1 - 4.6e-27 94.9 0.0 6.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PseudoU_synth_1 PF01416.20 KXZ51601.1 - 1e-09 38.8 0.1 9.5e-07 29.3 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase Kinase-like PF14531.6 KXZ51601.1 - 0.008 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KXZ51603.1 - 3.8e-33 115.0 0.0 1.7e-31 109.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51603.1 - 4.3e-30 104.9 0.0 6.4e-28 97.7 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KXZ51603.1 - 0.0047 16.3 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfatase PF00884.23 KXZ51604.1 - 6.6e-51 173.5 0.1 8.8e-51 173.1 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXZ51604.1 - 2.1e-05 24.3 0.1 0.14 11.7 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KXZ51604.1 - 0.011 14.9 0.0 0.066 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) DUF229 PF02995.17 KXZ51604.1 - 0.051 12.2 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase PF00884.23 KXZ51605.1 - 4.4e-54 184.0 0.0 6.1e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXZ51605.1 - 0.0029 17.3 0.1 0.02 14.5 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DcpS_C PF11969.8 KXZ51606.1 - 2.8e-28 98.7 0.3 7.6e-28 97.3 0.2 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KXZ51606.1 - 7.6e-18 65.3 0.0 1.2e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Sulfatase PF00884.23 KXZ51607.1 - 7.7e-53 179.9 0.0 1e-52 179.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXZ51607.1 - 0.0041 16.8 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Cnd1 PF12717.7 KXZ51609.1 - 8.9e-24 84.4 2.7 1.4e-21 77.2 0.0 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KXZ51609.1 - 6.7e-08 32.6 0.0 2.7e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term DASH_Spc19 PF08287.11 KXZ51609.1 - 0.04 13.8 0.1 0.04 13.8 0.1 2.3 2 0 0 2 2 2 0 Spc19 DUF3340 PF11818.8 KXZ51609.1 - 0.27 11.4 8.0 0.28 11.3 5.9 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Myc_N PF01056.18 KXZ51609.1 - 0.71 9.7 8.4 1.4 8.7 8.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Macoilin PF09726.9 KXZ51609.1 - 1.7 7.1 6.1 3 6.3 6.1 1.3 1 0 0 1 1 1 0 Macoilin family 2-oxoacid_dh PF00198.23 KXZ51611.1 - 5.2e-36 124.2 0.0 9.3e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXZ51611.1 - 1.5e-19 69.6 2.0 4.5e-19 68.0 2.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme PYNP_C PF07831.13 KXZ51611.1 - 0.0072 16.0 0.9 0.25 11.0 0.1 2.4 1 1 1 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.19 KXZ51611.1 - 0.013 15.4 0.3 0.027 14.4 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 KXZ51611.1 - 0.021 14.6 4.0 0.05 13.4 0.2 2.7 2 1 1 3 3 3 0 Biotin-lipoyl like DUF2118 PF09891.9 KXZ51611.1 - 0.023 14.7 0.4 0.69 9.8 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Pheromone PF08015.11 KXZ51611.1 - 0.53 11.4 5.1 1.3 10.1 5.1 1.7 1 0 0 1 1 1 0 Fungal mating-type pheromone FAP PF07174.11 KXZ51611.1 - 1.7 8.0 34.1 3.4 7.0 32.9 1.9 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Methyltransf_FA PF12248.8 KXZ51612.1 - 1.1e-10 41.7 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase F5_F8_type_C PF00754.25 KXZ51612.1 - 1.1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain YqfQ PF14181.6 KXZ51612.1 - 3.3 7.9 0.0 3.3 7.9 0.0 3.2 3 0 0 3 3 3 0 YqfQ-like protein Hint PF01079.20 KXZ51613.1 - 1.3e-17 64.0 0.0 2.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Hint module EF-hand_5 PF13202.6 KXZ51613.1 - 0.0073 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ51613.1 - 0.043 13.4 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF4483 PF14825.6 KXZ51614.1 - 1.6e-42 145.0 0.0 3.4e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) RTT107_BRCT_5 PF16770.5 KXZ51614.1 - 0.018 14.9 0.0 0.095 12.6 0.0 1.9 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Amidinotransf PF02274.17 KXZ51615.1 - 1.8e-57 195.0 0.0 2.2e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase adh_short PF00106.25 KXZ51616.1 - 0.002 17.6 0.0 0.029 13.8 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ51616.1 - 0.0054 16.3 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SSF PF00474.17 KXZ51617.1 - 3.8e-15 55.7 36.2 3.8e-15 55.7 36.2 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family RAMP4 PF06624.12 KXZ51617.1 - 0.25 11.4 0.8 0.8 9.8 0.8 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 SSF PF00474.17 KXZ51618.1 - 2.5e-19 69.4 33.5 2.5e-19 69.4 33.5 2.0 2 0 0 2 2 2 1 Sodium:solute symporter family DUF3377 PF11857.8 KXZ51618.1 - 0.9 9.5 2.7 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Amidase PF01425.21 KXZ51619.1 - 4.5e-53 180.8 1.4 6.1e-53 180.4 1.4 1.0 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 KXZ51620.1 - 3.7e-83 279.2 0.1 6.6e-83 278.4 0.1 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KXZ51620.1 - 4.1e-57 193.1 0.0 8.4e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KXZ51620.1 - 1.8e-42 145.4 0.0 4.6e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KXZ51620.1 - 1.1e-36 125.2 0.0 4.6e-35 120.0 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXZ51620.1 - 3.8e-36 124.0 2.6 4.1e-36 123.9 0.1 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXZ51620.1 - 1.3e-11 44.1 0.4 4.2e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXZ51620.1 - 2.2e-06 27.4 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KXZ51620.1 - 6.1e-05 22.8 6.9 0.00011 21.9 0.0 3.6 3 1 1 4 4 4 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXZ51620.1 - 0.0045 17.7 0.6 0.34 11.6 0.0 3.2 2 0 0 2 2 2 1 HlyD family secretion protein ATP-grasp PF02222.22 KXZ51620.1 - 0.0045 16.6 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.6 KXZ51620.1 - 0.02 14.9 0.1 0.051 13.5 0.1 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATP-grasp_5 PF13549.6 KXZ51620.1 - 0.026 14.0 0.0 0.079 12.4 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.19 KXZ51620.1 - 0.027 14.4 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RimK PF08443.11 KXZ51620.1 - 0.027 14.1 0.0 0.087 12.4 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain LAL_C2 PF18603.1 KXZ51620.1 - 0.05 13.8 0.0 0.05 13.8 0.0 5.0 5 0 0 5 5 3 0 L-amino acid ligase C-terminal domain 2 zf-Tim10_DDP PF02953.15 KXZ51621.1 - 5.9e-20 70.7 5.0 7.4e-20 70.4 5.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pardaxin PF07425.11 KXZ51621.1 - 0.052 13.2 0.7 0.083 12.5 0.7 1.3 1 0 0 1 1 1 0 Pardaxin LIAS_N PF16881.5 KXZ51622.1 - 2.2e-17 63.4 0.0 4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KXZ51622.1 - 8.4e-14 52.3 0.0 1.4e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily S4 PF01479.25 KXZ51623.1 - 9.9e-13 47.6 1.4 9.9e-13 47.6 1.4 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KXZ51623.1 - 1.1e-07 32.7 1.4 3.3e-07 31.1 0.9 2.1 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain zf-MYND PF01753.18 KXZ51624.1 - 2.8e-06 27.3 8.0 2.8e-06 27.3 8.0 2.0 2 0 0 2 2 2 1 MYND finger HTH_51 PF18558.1 KXZ51624.1 - 0.24 11.3 0.0 0.44 10.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PE PF00934.20 KXZ51624.1 - 0.37 11.1 6.6 1.7 9.0 0.1 3.8 3 1 0 3 3 3 0 PE family Enkurin PF13864.6 KXZ51626.1 - 1.5e-27 95.9 2.3 1.5e-27 95.9 2.3 1.9 2 0 0 2 2 2 1 Calmodulin-binding APG17 PF04108.12 KXZ51626.1 - 0.073 12.2 0.6 0.076 12.1 0.6 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 Pkinase PF00069.25 KXZ51627.1 - 9.9e-43 146.4 0.1 3.6e-42 144.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51627.1 - 1e-21 77.4 0.9 5e-21 75.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ51627.1 - 1e-05 24.5 4.7 7e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXZ51627.1 - 2.7e-05 23.6 0.0 2.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like TFIIA PF03153.13 KXZ51627.1 - 0.063 13.3 31.2 0.16 11.9 31.2 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PNPase_C PF12111.8 KXZ51629.1 - 1 8.8 10.8 6.6 6.2 0.5 3.7 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal AF-4 PF05110.13 KXZ51630.1 - 0.64 8.0 6.9 0.86 7.6 6.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein COPIIcoated_ERV PF07970.12 KXZ51632.1 - 1.2e-31 110.2 0.1 1.5e-31 109.9 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXZ51632.1 - 1e-10 41.8 0.2 2.2e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CPSase_L_D2 PF02786.17 KXZ51633.1 - 1.7e-108 361.0 0.1 1.8e-71 240.0 0.1 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KXZ51633.1 - 1.6e-39 135.1 0.1 3.7e-39 133.8 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 KXZ51633.1 - 2.2e-17 63.0 0.0 7.6e-17 61.3 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 KXZ51633.1 - 2.3e-12 46.8 0.0 5.4e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXZ51633.1 - 4.9e-11 42.5 0.0 3.3e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KXZ51633.1 - 5.5e-10 39.1 0.1 0.00022 21.0 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 KXZ51633.1 - 3.1e-09 36.6 0.0 0.0025 17.4 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KXZ51633.1 - 3.9e-07 30.2 0.0 0.00081 19.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KXZ51633.1 - 0.00067 19.5 0.0 0.057 13.2 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_2 PF08442.10 KXZ51633.1 - 0.0013 18.4 0.0 1.7 8.1 0.0 3.3 4 0 0 4 4 4 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KXZ51633.1 - 0.023 14.1 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain SAM_3 PF18016.1 KXZ51633.1 - 0.044 13.6 0.2 1.5 8.7 0.0 2.6 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) DUF4176 PF13780.6 KXZ51633.1 - 0.086 12.9 0.0 7.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) Chorismate_bind PF00425.18 KXZ51634.1 - 0.19 11.2 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 chorismate binding enzyme PP2C PF00481.21 KXZ51635.1 - 1.8e-40 139.3 0.0 2.4e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C CPBP PF02517.16 KXZ51637.1 - 1.7e-15 57.1 1.4 1.7e-15 57.1 1.4 2.2 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Pkinase PF00069.25 KXZ51638.1 - 1.9e-43 148.7 0.0 1.3e-41 142.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51638.1 - 2.7e-43 148.1 0.0 3.5e-40 137.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ51638.1 - 0.00049 19.0 0.0 0.00076 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ51638.1 - 0.0054 16.7 0.2 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Herpes_gE PF02480.16 KXZ51638.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E WD40 PF00400.32 KXZ51639.1 - 3.4e-70 230.2 30.7 8.8e-09 35.9 0.1 12.8 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51639.1 - 6.9e-45 151.3 0.0 9.9e-05 22.6 0.0 10.2 6 2 4 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ51639.1 - 2.1e-12 46.6 2.1 4.4 6.2 0.0 8.8 7 1 2 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXZ51639.1 - 8.4e-11 41.5 9.8 1.2 9.2 0.0 8.3 8 0 0 8 8 8 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KXZ51639.1 - 1.7e-09 37.9 0.0 0.057 13.3 0.0 5.1 5 0 0 5 5 5 3 Eukaryotic translation initiation factor eIF2A NACHT PF05729.12 KXZ51639.1 - 1.4e-05 25.1 0.1 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Proteasome_A_N PF10584.9 KXZ51639.1 - 0.00053 19.6 0.6 16 5.2 0.0 5.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 KXZ51639.1 - 0.008 15.5 11.9 3.7 6.8 0.1 6.8 5 2 3 9 9 9 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KXZ51639.1 - 0.18 11.8 0.8 18 5.5 0.1 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat DPPIV_N PF00930.21 KXZ51639.1 - 1.1 7.9 4.3 92 1.6 0.1 5.2 7 0 0 7 7 7 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TFIIIC_delta PF12657.7 KXZ51639.1 - 8 6.3 8.6 95 2.8 0.0 5.5 7 1 1 8 8 8 0 Transcription factor IIIC subunit delta N-term zf-4CXXC_R1 PF10497.9 KXZ51640.1 - 4.5e-11 42.9 16.4 7e-05 23.0 14.9 2.6 1 1 1 2 2 2 2 Zinc-finger domain of monoamine-oxidase A repressor R1 Pkinase PF00069.25 KXZ51641.1 - 5.3e-29 101.4 0.0 3.6e-26 92.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51641.1 - 1.5e-24 86.7 0.0 3.3e-21 75.7 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ51641.1 - 0.00013 20.9 0.0 0.00019 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ51641.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CRAL_TRIO_2 PF13716.6 KXZ51642.1 - 2.2e-27 95.9 0.0 2.7e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KXZ51642.1 - 6.7e-05 22.7 0.0 0.00057 19.6 0.0 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain Pro_isomerase PF00160.21 KXZ51643.1 - 0.00062 20.1 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rib_recp_KP_reg PF05104.12 KXZ51643.1 - 0.064 14.3 3.5 0.099 13.7 3.5 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Pkinase PF00069.25 KXZ51644.1 - 4.7e-27 95.0 0.0 2.9e-24 85.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51644.1 - 2.2e-25 89.5 0.0 1e-21 77.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ51644.1 - 0.00086 19.3 0.0 0.0016 18.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ51644.1 - 0.26 10.0 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HTH_28 PF13518.6 KXZ51645.1 - 0.001 19.2 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.6 KXZ51645.1 - 0.017 15.1 0.0 1.5 8.9 0.0 2.5 2 1 1 3 3 3 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 KXZ51645.1 - 0.019 15.3 0.0 0.083 13.2 0.0 1.9 2 0 0 2 2 2 0 Transposase YdaS_antitoxin PF15943.5 KXZ51645.1 - 0.086 12.7 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Topoisom_bac PF01131.20 KXZ51646.1 - 1.8e-97 327.0 0.0 1.3e-96 324.1 0.0 1.9 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KXZ51646.1 - 6.7e-11 42.3 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zinc_ribbon_12 PF11331.8 KXZ51646.1 - 0.095 12.5 7.5 3 7.7 1.4 3.3 2 1 0 2 2 2 0 Probable zinc-ribbon domain Ribosomal_S27e PF01667.17 KXZ51646.1 - 0.63 9.8 6.7 0.055 13.2 0.5 2.4 3 0 0 3 3 3 0 Ribosomal protein S27 ubiquitin PF00240.23 KXZ51647.1 - 1.5e-07 31.1 0.3 3.8e-07 29.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXZ51647.1 - 1.6e-05 25.3 0.1 7.1e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KXZ51647.1 - 0.0097 15.7 0.2 0.059 13.2 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KXZ51647.1 - 0.081 13.0 0.2 0.32 11.1 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Trypsin_2 PF13365.6 KXZ51648.1 - 1.1e-05 26.3 0.0 2.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain zinc_ribbon_12 PF11331.8 KXZ51648.1 - 0.094 12.5 4.1 4.3 7.2 0.3 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon domain Malate_DH PF12434.8 KXZ51648.1 - 0.21 11.6 0.0 0.58 10.2 0.0 1.7 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Ribosomal_S27e PF01667.17 KXZ51648.1 - 0.26 11.0 0.1 0.26 11.0 0.1 2.2 3 0 0 3 3 3 0 Ribosomal protein S27 ubiquitin PF00240.23 KXZ51649.1 - 5.9e-07 29.2 0.1 1.5e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXZ51649.1 - 1.3e-05 25.5 0.1 6e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KXZ51649.1 - 0.12 12.5 0.1 0.65 10.1 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain PIN_4 PF13638.6 KXZ51651.1 - 3.3e-11 43.6 0.0 5.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 PIN domain GYF PF02213.16 KXZ51651.1 - 0.0028 17.3 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXZ51651.1 - 0.042 13.6 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 GYF domain 2 Pentapeptide PF00805.22 KXZ51654.1 - 1.1e-18 66.5 13.6 5.2e-08 32.4 0.3 3.3 1 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KXZ51654.1 - 9.6e-12 44.9 1.5 3.9e-05 23.7 0.2 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KXZ51654.1 - 8.8e-11 41.8 5.0 0.00068 19.7 0.1 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) CfAFP PF05264.11 KXZ51654.1 - 0.0044 17.0 0.1 0.27 11.2 0.0 2.3 1 1 1 2 2 2 1 Choristoneura fumiferana antifreeze protein (CfAFP) PSII_Ycf12 PF05969.11 KXZ51654.1 - 0.31 11.1 3.1 0.58 10.2 3.1 1.4 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 Glyco_transf_5 PF08323.11 KXZ51655.1 - 1.8e-68 230.9 0.0 3.2e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXZ51655.1 - 4.5e-19 68.6 0.0 8.9e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ51655.1 - 5.3e-14 52.8 0.2 1.2e-13 51.6 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 UCH PF00443.29 KXZ51657.1 - 1e-30 107.1 0.0 1.4e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXZ51657.1 - 2.7e-14 53.2 2.5 4.9e-14 52.4 2.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXZ51657.1 - 0.062 12.9 0.0 0.49 9.9 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KXZ51657.1 - 0.32 10.8 1.3 0.66 9.8 1.3 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger MEKHLA PF08670.11 KXZ51658.1 - 0.00014 21.8 0.0 0.00038 20.4 0.0 1.8 1 0 0 1 1 1 1 MEKHLA domain FAST_1 PF06743.15 KXZ51659.1 - 0.0028 17.5 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 TPPK_C PF12555.8 KXZ51659.1 - 0.052 13.6 5.4 0.16 12.0 2.5 2.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Ank_2 PF12796.7 KXZ51660.1 - 2.2e-12 47.4 0.3 4.5e-06 27.1 0.0 4.4 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51660.1 - 3e-08 34.0 5.8 0.038 14.6 0.5 6.2 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51660.1 - 7.7e-06 25.9 1.3 0.27 11.9 0.0 6.2 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ51660.1 - 0.21 11.9 6.5 61 4.1 0.2 5.1 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51660.1 - 0.41 11.2 3.7 5.4 7.6 0.1 3.8 4 0 0 4 4 4 0 Ankyrin repeat ATX_III PF08098.11 KXZ51660.1 - 9.5 6.4 10.9 5.6 7.1 0.3 3.4 3 0 0 3 3 3 0 Anemonia sulcata toxin III family Alpha_kinase PF02816.18 KXZ51661.1 - 6e-53 179.7 0.0 8.2e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 KXZ51661.1 - 2.9e-05 24.6 7.9 0.021 15.5 0.1 4.2 3 0 0 3 3 3 2 Sel1 repeat Pkinase PF00069.25 KXZ51662.1 - 6.6e-08 32.2 0.0 7.6e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51662.1 - 1.8e-05 24.2 0.0 2.1e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Alginate_lyase2 PF08787.11 KXZ51663.1 - 1e-27 97.6 0.0 1.2e-27 97.3 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Laminin_G_3 PF13385.6 KXZ51663.1 - 0.0055 16.9 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily NDK PF00334.19 KXZ51664.1 - 2.3e-54 183.0 0.0 2.8e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ABC_tran PF00005.27 KXZ51666.1 - 1.9e-25 90.0 0.0 2.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXZ51666.1 - 1.1e-18 67.5 18.0 1.1e-18 67.5 18.0 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXZ51666.1 - 3.1e-11 43.6 0.0 1.6e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 KXZ51666.1 - 7.8e-05 22.1 8.9 0.00014 21.3 8.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF2705 PF10920.8 KXZ51666.1 - 0.0035 16.7 8.7 0.0035 16.7 8.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2705) IstB_IS21 PF01695.17 KXZ51666.1 - 0.094 12.4 0.0 15 5.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein SMC_N PF02463.19 KXZ51666.1 - 0.097 12.1 0.0 8.4 5.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ51666.1 - 0.097 12.4 0.1 0.29 10.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXZ51666.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 KXZ51666.1 - 0.21 11.3 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KXZ51666.1 - 0.29 11.6 0.3 0.5 10.8 0.3 1.3 1 0 0 1 1 1 0 AAA domain DUF2070 PF09843.9 KXZ51666.1 - 3.9 5.6 8.9 7 4.8 8.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LRR_8 PF13855.6 KXZ51669.1 - 0.038 13.8 0.9 13 5.6 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat Peroxin-3 PF04882.12 KXZ51670.1 - 0.0026 16.8 0.0 1.3 7.9 0.1 2.4 2 0 0 2 2 2 2 Peroxin-3 Tricorn_C1 PF14684.6 KXZ51670.1 - 0.18 11.9 0.0 8.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain TSNAXIP1_N PF15739.5 KXZ51671.1 - 0.00078 19.8 3.3 0.009 16.4 3.3 2.3 1 1 0 1 1 1 1 Translin-associated factor X-interacting N-terminus HeLo PF14479.6 KXZ51671.1 - 0.0008 19.3 0.7 0.0011 18.8 0.7 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation DehI PF10778.9 KXZ51671.1 - 0.067 13.3 7.6 0.082 13.0 0.1 2.5 1 1 1 2 2 2 0 Halocarboxylic acid dehydrogenase DehI Fumerase PF05681.14 KXZ51671.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) GAS PF13851.6 KXZ51671.1 - 4.3 6.6 13.2 0.89 8.9 8.8 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HYLS1_C PF15311.6 KXZ51672.1 - 0.00084 20.0 8.3 0.12 13.1 8.3 2.6 1 1 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus B5 PF03484.15 KXZ51672.1 - 0.24 11.7 0.7 0.3 11.4 0.7 1.3 1 1 0 1 1 1 0 tRNA synthetase B5 domain MAP70 PF07058.11 KXZ51673.1 - 8e-16 57.9 17.1 2.1e-14 53.2 2.3 2.1 2 0 0 2 2 2 2 Microtubule-associated protein 70 Fez1 PF06818.15 KXZ51673.1 - 0.00012 22.6 21.5 0.046 14.2 1.8 3.1 2 1 1 3 3 3 3 Fez1 FPP PF05911.11 KXZ51673.1 - 0.0016 16.7 6.3 0.024 12.8 1.8 2.1 2 0 0 2 2 2 2 Filament-like plant protein, long coiled-coil TMF_TATA_bd PF12325.8 KXZ51673.1 - 0.0017 18.6 15.8 0.016 15.4 1.5 4.0 3 1 0 3 3 3 2 TATA element modulatory factor 1 TATA binding HIP1_clath_bdg PF16515.5 KXZ51673.1 - 0.0083 16.7 1.6 0.0083 16.7 1.6 3.4 2 1 1 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Pox_A_type_inc PF04508.12 KXZ51673.1 - 0.01 15.6 0.1 0.053 13.4 0.0 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat APG6_N PF17675.1 KXZ51673.1 - 0.016 15.8 0.9 0.016 15.8 0.9 3.7 3 1 1 4 4 4 0 Apg6 coiled-coil region ATG16 PF08614.11 KXZ51673.1 - 0.081 13.1 25.7 1.5 9.0 4.5 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 KXZ51673.1 - 0.11 12.7 0.2 0.11 12.7 0.2 3.1 4 0 0 4 4 3 0 Tho complex subunit 7 KLRAQ PF10205.9 KXZ51673.1 - 0.16 12.2 11.0 1.9 8.8 0.6 3.3 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein ABC_tran_CTD PF16326.5 KXZ51673.1 - 0.25 11.6 15.5 16 5.8 0.4 5.3 4 2 0 4 4 4 0 ABC transporter C-terminal domain SPX PF03105.19 KXZ51673.1 - 1.3 8.8 18.2 2.7 7.8 2.2 2.2 2 0 0 2 2 2 0 SPX domain BRE1 PF08647.11 KXZ51673.1 - 1.7 8.8 21.6 1.2 9.3 2.2 3.5 4 0 0 4 4 3 0 BRE1 E3 ubiquitin ligase DUF812 PF05667.11 KXZ51673.1 - 2.1 7.1 13.3 2.4 7.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF641 PF04859.12 KXZ51673.1 - 2.3 8.6 11.9 4.2 7.7 1.4 3.2 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF4094 PF13334.6 KXZ51673.1 - 3.2 8.2 0.0 3.2 8.2 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4094) TPD52 PF04201.15 KXZ51673.1 - 3.6 7.2 12.0 2.2 7.9 4.0 3.2 2 1 0 2 2 2 0 Tumour protein D52 family FAM76 PF16046.5 KXZ51673.1 - 3.7 6.8 16.1 0.65 9.3 2.5 3.0 1 1 1 3 3 3 0 FAM76 protein ADIP PF11559.8 KXZ51673.1 - 3.9 7.6 17.7 3 7.9 1.9 4.0 3 1 0 4 4 4 0 Afadin- and alpha -actinin-Binding DoxX PF07681.12 KXZ51674.1 - 0.033 14.8 8.8 0.033 14.8 8.8 2.4 3 0 0 3 3 3 0 DoxX SURF4 PF02077.15 KXZ51674.1 - 0.036 13.6 0.0 0.036 13.6 0.0 2.3 2 1 0 2 2 2 0 SURF4 family Peptidase_A22B PF04258.13 KXZ51676.1 - 2.6e-50 171.5 0.4 1e-31 110.6 0.0 2.1 2 0 0 2 2 2 2 Signal peptide peptidase RCC1_2 PF13540.6 KXZ51677.1 - 9.2e-14 50.8 22.3 3.6e-06 26.6 0.1 6.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXZ51677.1 - 1.2e-12 48.2 6.8 0.0015 19.1 0.0 7.4 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat SH3_16 PF18348.1 KXZ51677.1 - 0.005 16.6 1.1 1.1 9.1 0.1 2.7 2 0 0 2 2 2 2 Bacterial dipeptidyl-peptidase Sh3 domain Reg_prop PF07494.11 KXZ51677.1 - 0.015 15.5 0.2 0.16 12.3 0.1 2.7 3 0 0 3 3 3 0 Two component regulator propeller HSP20 PF00011.21 KXZ51679.1 - 7.8e-19 67.7 0.1 9.5e-16 57.8 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXZ51679.1 - 9.9e-06 25.0 0.0 1.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PDZ_3 PF17815.1 KXZ51680.1 - 1.4e-36 125.5 0.0 2.1e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KXZ51680.1 - 4.5e-17 63.3 1.6 6.4e-17 62.8 0.6 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXZ51680.1 - 2.4e-08 34.1 0.0 4.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KXZ51680.1 - 7e-07 29.5 0.1 5.9e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KXZ51680.1 - 0.11 12.4 3.2 0.31 10.9 0.4 3.0 3 1 0 3 3 3 0 PDZ domain DUF2268 PF10026.9 KXZ51680.1 - 0.13 11.8 0.0 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) EF-hand_7 PF13499.6 KXZ51681.1 - 5.3e-21 74.8 1.4 3e-13 50.0 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ51681.1 - 1e-16 59.2 2.6 0.00036 19.9 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KXZ51681.1 - 4.4e-12 44.9 2.8 0.0034 17.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXZ51681.1 - 2.1e-08 33.9 1.0 4.2e-07 29.7 0.3 3.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ51681.1 - 3.2e-06 26.4 2.6 0.1 12.2 0.3 4.0 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 KXZ51681.1 - 0.00026 21.3 0.2 0.13 12.6 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Arm PF00514.23 KXZ51682.1 - 2.5e-09 36.8 14.8 0.0012 18.9 0.0 6.2 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXZ51682.1 - 3.1e-06 27.5 23.2 0.0012 19.3 3.1 5.1 5 2 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 KXZ51682.1 - 0.00027 21.3 22.3 0.0085 16.5 2.3 4.1 2 2 2 4 4 4 3 HEAT repeats Cnd1 PF12717.7 KXZ51682.1 - 0.0021 18.1 0.1 0.078 13.0 0.0 2.7 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXZ51682.1 - 0.0087 16.2 16.7 1.6 9.2 0.1 6.2 6 1 1 7 7 7 2 HEAT repeat DUF5044 PF16447.5 KXZ51682.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5044) Ank_4 PF13637.6 KXZ51683.1 - 0.00078 20.0 0.0 2.8 8.6 0.0 3.8 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Amidohydro_2 PF04909.14 KXZ51683.1 - 0.019 14.7 1.0 0.03 14.1 1.0 1.4 1 1 0 1 1 1 0 Amidohydrolase Bacteriocin_II PF01721.18 KXZ51683.1 - 0.097 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Class II bacteriocin DUF4224 PF13986.6 KXZ51684.1 - 0.032 14.1 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) PDEase_I PF00233.19 KXZ51686.1 - 9.5e-73 244.8 1.3 1.1e-57 195.5 0.0 3.1 1 1 2 3 3 3 3 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 KXZ51687.1 - 5.3e-94 314.4 0.0 2.6e-58 197.6 0.0 2.2 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase FANC_SAP PF18081.1 KXZ51687.1 - 0.001 19.2 1.1 1.9 8.7 0.1 3.0 2 0 0 2 2 2 2 Fanconi anemia-associated nuclease SAP domain CHASE PF03924.13 KXZ51687.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 CHASE domain Peptidase_M48_N PF16491.5 KXZ51688.1 - 1.2e-58 198.0 3.8 2.1e-58 197.2 3.8 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KXZ51688.1 - 6e-41 140.4 0.0 1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 KXZ51688.1 - 0.017 15.0 0.0 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 SprT-like family Peptidase_M78 PF06114.13 KXZ51688.1 - 0.062 13.2 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 IrrE N-terminal-like domain DUF4538 PF15061.6 KXZ51688.1 - 0.16 11.7 0.4 1 9.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Choline_transpo PF04515.12 KXZ51690.1 - 3.4e-47 161.2 28.0 3.4e-47 161.2 28.0 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Tim17 PF02466.19 KXZ51691.1 - 1e-08 35.5 1.4 1.6e-08 34.9 1.4 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Myc_N PF01056.18 KXZ51692.1 - 0.16 11.8 1.8 0.28 11.1 1.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_L29 PF00831.23 KXZ51693.1 - 3.4e-19 68.6 4.2 7.2e-19 67.5 0.3 2.4 2 0 0 2 2 2 1 Ribosomal L29 protein HLH PF00010.26 KXZ51693.1 - 0.041 13.8 2.2 0.57 10.2 0.2 2.4 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain EF-hand_7 PF13499.6 KXZ51694.1 - 2.5e-06 27.8 0.1 4.5e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ51694.1 - 2.1e-05 23.8 0.3 6.5e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXZ51694.1 - 4.5e-05 23.2 1.0 0.00015 21.5 0.7 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ51694.1 - 0.0017 18.2 0.0 0.0069 16.2 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KXZ51694.1 - 0.094 12.2 1.9 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 EF hand PAP_fibrillin PF04755.12 KXZ51695.1 - 6e-05 23.1 0.0 7.6e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 PAP_fibrillin Arm PF00514.23 KXZ51698.1 - 0.001 19.0 38.4 2.1 8.5 0.1 12.7 14 1 0 14 14 14 5 Armadillo/beta-catenin-like repeat DUF4704 PF15787.5 KXZ51698.1 - 0.13 11.4 3.3 0.73 9.0 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4704) PRKCSH-like PF12999.7 KXZ51700.1 - 4.6e-47 160.1 0.4 4.6e-47 160.1 0.4 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KXZ51700.1 - 2.6e-14 53.2 0.1 2.6e-14 53.2 0.1 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KXZ51700.1 - 0.00019 22.4 3.1 0.00047 21.1 1.6 2.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Caldesmon PF02029.15 KXZ51700.1 - 0.17 10.6 29.8 0.33 9.7 29.8 1.4 1 1 0 1 1 1 0 Caldesmon DUF3029 PF11230.8 KXZ51700.1 - 0.3 9.4 2.2 0.46 8.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Fib_alpha PF08702.10 KXZ51700.1 - 1.3 9.2 5.7 39 4.4 0.0 3.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KXZ51700.1 - 2.3 8.3 5.1 0.74 9.9 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) MBOAT PF03062.19 KXZ51701.1 - 7.8e-13 48.5 1.1 2e-12 47.2 1.1 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RRM_1 PF00076.22 KXZ51703.1 - 0.031 14.1 0.0 0.066 13.0 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 KXZ51704.1 - 6e-34 117.3 0.0 1e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ51704.1 - 1.5e-05 25.0 0.0 5.7e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KXZ51704.1 - 8e-05 22.4 0.0 0.0019 18.0 0.0 3.0 3 0 0 3 3 3 1 AAA+ lid domain RuvB_N PF05496.12 KXZ51704.1 - 0.00014 21.7 0.0 0.00041 20.1 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ51704.1 - 0.00017 22.0 1.2 0.0023 18.3 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXZ51704.1 - 0.0078 16.5 0.1 0.41 10.9 0.0 2.9 1 1 2 3 3 3 1 AAA domain AAA_30 PF13604.6 KXZ51704.1 - 0.013 15.2 0.0 0.04 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXZ51704.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KXZ51704.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXZ51704.1 - 0.024 14.8 0.0 0.07 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXZ51704.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ51704.1 - 0.082 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain HpaP PF09483.10 KXZ51704.1 - 0.15 12.3 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Type III secretion protein (HpaP) PolyA_pol PF01743.20 KXZ51705.1 - 5.2e-30 104.5 0.4 6.6e-30 104.1 0.4 1.1 1 0 0 1 1 1 1 Poly A polymerase head domain UCH PF00443.29 KXZ51706.1 - 8.8e-47 159.7 0.0 1.1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ51706.1 - 2.1e-14 53.8 0.0 1.3e-13 51.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KXZ51706.1 - 1.9e-06 27.5 0.0 4.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 KXZ51706.1 - 0.014 14.9 0.0 0.06 12.8 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1631 PF07793.11 KXZ51706.1 - 0.087 11.2 0.2 0.15 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PolyA_pol_RNAbd PF12627.7 KXZ51707.1 - 8.8e-07 28.6 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Androgen_recep PF02166.16 KXZ51707.1 - 0.052 12.4 4.3 1.2 7.8 1.0 2.1 2 0 0 2 2 2 0 Androgen receptor Sulfotransfer_1 PF00685.27 KXZ51708.1 - 1.1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ51708.1 - 3.4e-05 24.3 0.0 0.00094 19.6 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family HAUS5 PF14817.6 KXZ51710.1 - 8.9e-05 21.4 11.1 0.49 9.1 2.8 3.2 3 0 0 3 3 3 3 HAUS augmin-like complex subunit 5 Lebercilin PF15619.6 KXZ51710.1 - 0.02 14.5 6.5 0.1 12.3 4.1 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MRPL52 PF18699.1 KXZ51710.1 - 0.62 10.3 3.4 2.4 8.4 0.1 2.5 2 0 0 2 2 2 0 Mitoribosomal protein mL52 RRM_1 PF00076.22 KXZ51711.1 - 2.7e-60 200.1 0.0 8.7e-21 73.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXZ51711.1 - 3.2e-05 23.9 0.1 0.88 9.7 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 KXZ51711.1 - 0.0001 22.1 0.1 0.15 11.9 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KXZ51711.1 - 0.0001 21.9 0.0 0.72 9.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXZ51711.1 - 0.00027 21.0 0.0 3.1 7.9 0.0 3.3 3 0 0 3 3 3 1 Limkain b1 RRM_7 PF16367.5 KXZ51711.1 - 0.0032 17.5 0.0 0.076 13.1 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KXZ51711.1 - 0.055 13.5 0.0 8.7 6.4 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif TROVE PF05731.11 KXZ51712.1 - 2.5e-42 145.4 0.0 2.8e-24 86.0 0.0 3.1 2 1 0 2 2 2 2 TROVE domain SBF PF01758.16 KXZ51713.1 - 5.9e-29 101.2 9.0 5.9e-29 101.2 9.0 1.4 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 KXZ51713.1 - 1.3e-12 47.7 12.9 1.5e-12 47.4 12.9 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Ist1 PF03398.14 KXZ51714.1 - 3.4e-25 88.9 5.0 1.6e-23 83.4 3.8 2.1 1 1 1 2 2 2 2 Regulator of Vps4 activity in the MVB pathway NYD-SP28_assoc PF14775.6 KXZ51714.1 - 0.12 12.4 2.0 0.17 12.0 0.8 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain GATA PF00320.27 KXZ51715.1 - 1e-15 57.0 7.6 2.1e-15 56.0 7.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 KXZ51715.1 - 2 8.4 7.8 6.1 6.8 7.8 1.8 1 0 0 1 1 1 0 Nudix N-terminal EF_TS PF00889.19 KXZ51716.1 - 4.8e-36 124.3 0.0 1.8e-35 122.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor TS HEAT_2 PF13646.6 KXZ51717.1 - 9.8e-27 93.2 8.4 1.1e-11 44.9 0.2 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 KXZ51717.1 - 2.3e-23 80.4 3.0 0.00019 21.8 0.0 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KXZ51717.1 - 1.6e-05 24.8 7.8 0.053 13.8 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat TAF6_C PF07571.13 KXZ51717.1 - 0.0013 19.0 0.1 12 6.3 0.0 4.0 3 1 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 KXZ51717.1 - 0.002 18.6 6.4 0.14 12.7 0.3 5.0 4 2 2 6 6 6 1 HEAT-like repeat Chorismate_bind PF00425.18 KXZ51717.1 - 0.024 14.2 0.1 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 chorismate binding enzyme Arm PF00514.23 KXZ51717.1 - 0.14 12.3 0.1 4.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Transmemb_17 PF09799.9 KXZ51718.1 - 2.4e-16 60.3 8.0 4e-16 59.5 8.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein DUF4293 PF14126.6 KXZ51718.1 - 0.042 14.1 5.2 0.36 11.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) MFS_1 PF07690.16 KXZ51719.1 - 2.9e-32 112.0 39.3 7.1e-32 110.7 27.2 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Mac PF12464.8 KXZ51720.1 - 5.7e-13 48.9 0.5 8.2e-13 48.4 0.5 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KXZ51720.1 - 7.3e-13 48.0 5.4 2.8e-10 39.8 3.7 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KXZ51720.1 - 3.3e-11 42.4 9.7 1.9e-09 36.9 4.0 2.8 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Epimerase PF01370.21 KXZ51721.1 - 6.5e-15 55.3 0.1 1.1e-11 44.6 0.1 3.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXZ51721.1 - 1.1e-10 41.7 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXZ51721.1 - 4.6e-10 39.4 0.0 3.6e-05 23.3 0.0 2.6 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXZ51721.1 - 6.4e-06 25.5 0.0 0.00097 18.3 0.0 3.0 1 1 0 1 1 1 1 RmlD substrate binding domain Glyco_transf_4 PF13439.6 KXZ51721.1 - 6.7e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXZ51721.1 - 0.0035 17.8 0.4 0.02 15.3 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain adh_short PF00106.25 KXZ51721.1 - 0.0087 15.5 0.0 0.025 14.0 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KXZ51721.1 - 0.02 13.9 0.0 0.23 10.4 0.0 2.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.16 KXZ51721.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TraC_F_IV PF11130.8 KXZ51723.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer ApbA_C PF08546.11 KXZ51723.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Herpes_UL36 PF03586.13 KXZ51724.1 - 0.011 15.1 4.3 0.14 11.5 0.2 2.2 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein FAST_1 PF06743.15 KXZ51725.1 - 0.042 13.8 0.0 0.41 10.6 0.0 2.4 1 1 0 2 2 2 0 FAST kinase-like protein, subdomain 1 PLAT PF01477.23 KXZ51726.1 - 1e-299 974.1 0.0 1.2e-24 87.1 0.1 17.5 17 0 0 17 17 17 17 PLAT/LH2 domain Sod_Fe_C PF02777.18 KXZ51727.1 - 1.8e-39 134.0 0.2 6.6e-39 132.2 0.0 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXZ51727.1 - 2.3e-30 104.9 0.3 3.9e-30 104.2 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF5617 PF18493.1 KXZ51727.1 - 0.09 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) Pkinase_Tyr PF07714.17 KXZ51728.1 - 2.5e-42 144.9 0.0 6.8e-36 123.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ51728.1 - 9.4e-33 113.7 0.0 3.2e-26 92.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain GAF PF01590.26 KXZ51728.1 - 1.5e-08 35.3 0.0 3.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KXZ51728.1 - 7.2e-08 32.8 0.0 2.4e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KXZ51728.1 - 0.00014 22.2 0.0 0.00041 20.7 0.0 1.8 1 1 0 1 1 1 1 GAF domain Pkinase_fungal PF17667.1 KXZ51728.1 - 0.00025 20.0 0.0 0.00041 19.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PAS_8 PF13188.7 KXZ51728.1 - 0.0026 17.7 0.0 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 KXZ51728.1 - 0.0073 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KXZ51728.1 - 0.019 14.9 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold RIO1 PF01163.22 KXZ51728.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CoaE PF01121.20 KXZ51729.1 - 4.5e-23 81.8 0.0 7.6e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase TPR_11 PF13414.6 KXZ51731.1 - 7.5e-19 67.1 4.6 7.2e-08 32.0 0.7 5.6 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.17 KXZ51731.1 - 1.2e-18 65.7 9.5 4.8e-05 23.2 0.7 5.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ51731.1 - 6.2e-17 60.7 5.9 0.00011 22.4 0.4 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ51731.1 - 2.4e-16 58.8 7.3 1.5e-05 24.6 0.6 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ51731.1 - 2.4e-13 49.1 0.5 0.0025 17.9 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ51731.1 - 2.7e-09 37.5 19.6 3.8e-06 27.4 1.9 7.6 5 2 3 8 8 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ51731.1 - 2.9e-09 36.9 13.8 0.0008 19.5 0.0 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ51731.1 - 2.3e-08 34.4 17.2 0.0024 18.4 0.5 5.6 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ51731.1 - 9.5e-08 32.3 8.8 0.00031 21.3 1.0 9.2 5 2 4 9 9 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ51731.1 - 5.3e-06 26.1 6.3 0.027 14.5 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ51731.1 - 0.00048 20.4 25.6 0.0021 18.3 3.0 4.9 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ51731.1 - 0.0028 18.2 2.3 38 5.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ51731.1 - 1.6 9.1 17.6 0.3 11.4 1.0 4.3 2 1 1 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ51731.1 - 1.9 8.4 20.5 0.99 9.4 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Usp PF00582.26 KXZ51732.1 - 2.8e-18 66.8 23.1 1.3e-07 32.2 0.0 5.8 6 0 0 6 6 6 4 Universal stress protein family Dzip-like_N PF13815.6 KXZ51732.1 - 6.9e-12 45.4 0.0 6.9e-12 45.4 0.0 2.3 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Myc_N PF01056.18 KXZ51732.1 - 0.0033 17.4 0.4 0.0064 16.4 0.4 1.4 1 0 0 1 1 1 1 Myc amino-terminal region ABC_membrane PF00664.23 KXZ51733.1 - 8.2e-106 353.6 33.4 4.1e-57 193.9 7.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ51733.1 - 4.2e-72 241.1 0.0 9.3e-35 120.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXZ51733.1 - 1.9e-11 43.8 7.1 0.00089 18.8 0.0 4.5 4 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXZ51733.1 - 1.2e-08 35.5 1.3 0.0053 17.1 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXZ51733.1 - 4.4e-08 32.8 0.6 0.0057 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KXZ51733.1 - 3.1e-07 29.6 4.1 0.0092 14.8 0.1 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KXZ51733.1 - 6.8e-07 29.6 0.4 0.1 12.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXZ51733.1 - 4.6e-06 26.1 0.2 0.029 13.7 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_5 PF07728.14 KXZ51733.1 - 2.6e-05 24.2 1.7 2.2 8.3 0.0 4.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KXZ51733.1 - 2.9e-05 24.0 0.4 0.19 11.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KXZ51733.1 - 7.6e-05 22.6 0.0 0.45 10.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KXZ51733.1 - 0.00014 22.0 0.2 0.74 9.9 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 KXZ51733.1 - 0.00014 21.6 4.8 0.22 11.2 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 KXZ51733.1 - 0.00055 20.4 0.9 2.1 8.8 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KXZ51733.1 - 0.00084 18.6 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 KXZ51733.1 - 0.00097 18.8 0.4 1 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.20 KXZ51733.1 - 0.0012 18.7 0.1 0.53 10.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_21 PF13304.6 KXZ51733.1 - 0.0017 18.2 0.0 2 8.2 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KXZ51733.1 - 0.0036 17.5 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KXZ51733.1 - 0.0093 16.5 0.2 2.7 8.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXZ51733.1 - 0.01 15.4 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KXZ51733.1 - 0.012 15.9 3.7 6.1 7.2 0.4 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KXZ51733.1 - 0.014 15.1 0.2 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KXZ51733.1 - 0.039 13.9 0.6 6.9 6.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KXZ51733.1 - 0.046 13.4 0.0 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KXZ51733.1 - 0.082 12.1 0.0 6.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXZ51733.1 - 0.095 13.3 0.1 7.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXZ51733.1 - 0.13 12.2 2.3 52 3.7 0.0 3.9 4 0 0 4 4 4 0 NTPase RNA_helicase PF00910.22 KXZ51733.1 - 0.17 12.3 0.0 32 5.0 0.0 3.0 3 0 0 3 3 3 0 RNA helicase DUF3619 PF12279.8 KXZ51733.1 - 2.3 8.6 7.9 10 6.4 0.6 3.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3619) BPD_transp_1 PF00528.22 KXZ51734.1 - 0.00096 18.9 14.7 0.0067 16.2 1.5 3.1 3 0 0 3 3 3 2 Binding-protein-dependent transport system inner membrane component Dynamin_N PF00350.23 KXZ51736.1 - 1.7e-24 86.8 0.0 1.2e-11 45.0 0.0 2.2 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 KXZ51736.1 - 1.2e-13 51.1 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXZ51736.1 - 2.1e-05 24.5 0.3 0.0095 15.9 0.1 2.7 3 0 0 3 3 3 2 RsgA GTPase TMP-TENI PF02581.17 KXZ51736.1 - 0.00011 21.6 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase FeoB_N PF02421.18 KXZ51736.1 - 0.00051 19.6 0.1 0.38 10.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXZ51736.1 - 0.00081 19.0 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KXZ51736.1 - 0.014 14.7 0.6 2.6 7.3 0.0 2.9 2 1 0 2 2 2 0 AIG1 family IIGP PF05049.13 KXZ51736.1 - 0.035 13.2 0.0 0.56 9.2 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 KXZ51736.1 - 0.097 12.4 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KXZ51736.1 - 0.31 11.4 3.5 0.93 9.9 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain APH PF01636.23 KXZ51736.1 - 1.1 9.1 8.8 0.21 11.4 0.4 3.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family Ank_4 PF13637.6 KXZ51737.1 - 1.3e-05 25.7 0.1 5e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51737.1 - 0.00038 21.0 0.0 0.001 19.6 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ51737.1 - 0.005 17.1 0.2 0.52 10.7 0.0 3.2 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51737.1 - 0.011 16.2 0.1 3.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat TRP PF06011.12 KXZ51737.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel HNH PF01844.23 KXZ51738.1 - 5.7e-08 32.8 2.4 1.3e-07 31.7 2.4 1.6 1 1 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 KXZ51738.1 - 1.1e-06 28.4 3.0 2e-06 27.6 3.0 1.5 1 1 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 KXZ51738.1 - 0.019 14.9 0.1 0.048 13.6 0.1 1.7 1 1 0 1 1 1 0 HNH endonuclease HSP20 PF00011.21 KXZ51739.1 - 2.9e-14 53.1 0.0 4.6e-12 46.0 0.0 2.7 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXZ51739.1 - 4.5e-06 26.1 0.0 1.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Myc_N PF01056.18 KXZ51739.1 - 1 9.2 2.9 1.5 8.7 0.4 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Cyclin_N PF00134.23 KXZ51741.1 - 1.5e-15 57.1 0.3 2.2e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ51741.1 - 0.24 11.5 9.8 0.57 10.3 8.0 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 KXZ51741.1 - 0.29 11.5 0.8 0.68 10.3 0.8 1.5 1 0 0 1 1 1 0 Cyclin C-terminal domain Polyketide_cyc PF03364.20 KXZ51742.1 - 2e-12 47.5 0.1 3.5e-12 46.7 0.1 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KXZ51742.1 - 2.1e-07 31.3 0.1 3e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Wtap PF17098.5 KXZ51743.1 - 0.86 9.5 11.5 0.45 10.4 7.9 2.3 2 0 0 2 2 2 0 WTAP/Mum2p family Cnn_1N PF07989.11 KXZ51743.1 - 2.2 8.5 9.1 0.14 12.3 0.8 3.0 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 ArAE_2_N PF10337.9 KXZ51743.1 - 2.5 7.0 4.8 4 6.4 4.8 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Mannosyl_trans PF05007.13 KXZ51747.1 - 1.9e-59 201.6 13.7 9.4e-29 101.1 7.2 3.2 3 0 0 3 3 3 3 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KXZ51747.1 - 3.6e-13 49.3 2.1 1.1e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KXZ51747.1 - 2.5e-08 33.9 22.0 2.5e-08 33.9 22.0 5.5 3 1 1 5 5 5 2 Glycosyltransferase family 87 MAJIN PF15077.6 KXZ51748.1 - 0.81 9.4 5.9 1.1 9.0 5.9 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein FKBP_C PF00254.28 KXZ51749.1 - 5e-34 116.5 0.0 1e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KXZ51749.1 - 3.4e-16 59.7 0.0 3.4e-16 59.7 0.0 2.9 2 1 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 KXZ51749.1 - 0.0068 15.1 37.7 0.0086 14.7 37.7 1.1 1 0 0 1 1 1 1 Utp14 protein Nucleoplasmin PF03066.15 KXZ51749.1 - 0.033 14.7 0.0 0.096 13.2 0.0 1.8 2 0 0 2 2 2 0 Nucleoplasmin/nucleophosmin domain DUF4551 PF15087.6 KXZ51749.1 - 0.18 10.6 5.1 0.23 10.3 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PH PF00169.29 KXZ51750.1 - 4.9e-09 36.6 0.0 9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 PH domain Peptidase_C1 PF00112.23 KXZ51752.1 - 2.2e-33 116.2 4.8 2.2e-33 116.2 4.8 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1 PF00112.23 KXZ51753.1 - 4.1e-16 59.7 1.4 4.1e-16 59.7 1.4 2.3 3 0 0 3 3 3 1 Papain family cysteine protease AMP-binding PF00501.28 KXZ51754.1 - 1.4e-15 56.9 0.2 2.1e-15 56.3 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXZ51754.1 - 6.9e-06 25.9 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus SR-25 PF10500.9 KXZ51754.1 - 9.2 5.8 8.7 13 5.3 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NTP_transf_2 PF01909.23 KXZ51755.1 - 3.3e-09 36.9 0.0 5.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KXZ51755.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase GH3 PF03321.13 KXZ51755.1 - 0.083 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter DNA_pol_B_palm PF14792.6 KXZ51755.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm DUF4106 PF13388.6 KXZ51755.1 - 8.7 5.5 7.8 13 4.9 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TPR_1 PF00515.28 KXZ51756.1 - 0.15 12.0 0.5 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C1 PF00112.23 KXZ51757.1 - 6.9e-30 104.8 6.8 2.1e-17 64.0 1.0 2.9 2 1 1 3 3 3 2 Papain family cysteine protease Trypan_PARP PF05887.11 KXZ51757.1 - 0.0024 17.8 10.9 0.008 16.2 10.9 1.8 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Guanylate_cyc PF00211.20 KXZ51758.1 - 2.9e-53 180.2 0.0 4.9e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain EF-hand_6 PF13405.6 KXZ51759.1 - 3.8e-09 35.7 0.2 0.0021 17.9 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KXZ51759.1 - 1.9e-08 34.6 0.0 0.00018 21.9 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ51759.1 - 4.1e-08 32.3 0.2 0.00056 19.3 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 KXZ51759.1 - 7.6e-08 31.4 0.0 0.011 15.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KXZ51759.1 - 4.6e-06 26.4 0.1 0.00091 19.0 0.0 2.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_10 PF14788.6 KXZ51759.1 - 0.0029 17.4 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KXZ51759.1 - 0.16 12.3 0.0 8.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ALS2CR8 PF15299.6 KXZ51760.1 - 0.00024 21.1 0.0 0.003 17.5 0.0 2.0 2 0 0 2 2 2 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Castor_Poll_mid PF06241.12 KXZ51761.1 - 2.3e-12 46.8 0.0 8.3e-09 35.4 0.0 4.1 3 1 0 3 3 3 1 Castor and Pollux, part of voltage-gated ion channel TrkA_N PF02254.18 KXZ51761.1 - 0.0092 16.2 0.4 0.047 13.9 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain TrkA_C PF02080.21 KXZ51761.1 - 0.016 15.0 0.3 2.1 8.2 0.0 3.7 4 0 0 4 4 4 0 TrkA-C domain DUF3138 PF11336.8 KXZ51761.1 - 0.52 8.9 8.2 1.4 7.5 8.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BT1 PF03092.16 KXZ51762.1 - 3.7e-72 243.2 13.2 6.6e-38 130.2 1.4 2.0 2 0 0 2 2 2 2 BT1 family MFS_2 PF13347.6 KXZ51762.1 - 0.031 12.9 6.0 0.015 13.9 1.6 2.0 2 0 0 2 2 2 0 MFS/sugar transport protein ABC_tran PF00005.27 KXZ51764.1 - 4.9e-33 114.5 0.0 1.5e-20 74.1 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXZ51764.1 - 2.1e-10 40.9 0.0 0.011 15.5 0.0 3.5 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ51764.1 - 1e-07 31.7 0.0 0.12 11.8 0.0 3.3 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain HEAT_EZ PF13513.6 KXZ51764.1 - 1.7e-05 25.2 18.4 0.0033 17.9 0.3 4.7 4 2 0 4 4 3 2 HEAT-like repeat SbcCD_C PF13558.6 KXZ51764.1 - 7.6e-05 22.9 0.1 0.18 12.1 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Chromo PF00385.24 KXZ51764.1 - 0.0015 18.4 0.2 0.0031 17.4 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 4HB PF17947.1 KXZ51764.1 - 0.0035 17.4 0.0 0.0097 15.9 0.0 1.8 1 0 0 1 1 1 1 Four helical bundle domain AAA_22 PF13401.6 KXZ51764.1 - 0.0045 17.3 0.0 0.019 15.2 0.0 2.1 2 1 0 2 2 1 1 AAA domain HEAT PF02985.22 KXZ51764.1 - 0.0055 16.8 9.6 0.37 11.2 0.2 5.9 6 0 0 6 6 5 1 HEAT repeat AAA_23 PF13476.6 KXZ51764.1 - 0.0081 16.7 0.9 0.04 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KXZ51764.1 - 0.029 13.5 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DRIM PF07539.12 KXZ51764.1 - 0.036 12.4 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis AAA PF00004.29 KXZ51764.1 - 0.048 14.1 0.0 0.2 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ParcG PF10274.9 KXZ51764.1 - 0.097 12.8 0.0 2.5 8.2 0.0 2.7 1 1 2 3 3 3 0 Parkin co-regulated protein NACHT PF05729.12 KXZ51764.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.8 KXZ51764.1 - 0.12 9.9 1.3 0.28 8.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_18 PF13238.6 KXZ51764.1 - 0.13 12.8 0.1 0.7 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXZ51764.1 - 0.15 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXZ51764.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KXZ51764.1 - 0.21 11.3 0.0 0.54 9.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF676 PF05057.14 KXZ51765.1 - 8.1e-33 113.8 0.0 1.1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXZ51765.1 - 0.00073 19.3 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KXZ51765.1 - 0.0033 17.3 0.0 0.0044 16.9 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 KXZ51765.1 - 0.014 14.5 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 KXZ51765.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Ank_4 PF13637.6 KXZ51766.1 - 0.0061 17.1 0.2 0.064 13.9 0.2 2.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51766.1 - 0.0072 16.7 1.5 34 5.4 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KXZ51766.1 - 0.0086 16.6 0.2 0.023 15.3 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF4715 PF15835.5 KXZ51767.1 - 0.28 11.3 0.8 1.7 8.7 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) Herpes_UL73 PF03554.13 KXZ51767.1 - 1 9.4 2.4 44 4.2 0.0 2.6 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein DUF4865 PF16157.5 KXZ51769.1 - 0.037 14.0 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) P5CR_dimer PF14748.6 KXZ51771.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation PAN_4 PF14295.6 KXZ51773.1 - 2.3e-05 24.2 38.6 0.002 18.0 0.2 8.2 9 0 0 9 9 9 6 PAN domain SelR PF01641.18 KXZ51774.1 - 2e-52 176.4 0.2 2.3e-52 176.2 0.2 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 KXZ51774.1 - 0.0011 19.0 1.7 0.1 12.7 0.3 3.1 2 1 1 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_10 PF10058.9 KXZ51774.1 - 0.015 15.0 0.4 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ACC PF17848.1 KXZ51774.1 - 0.051 13.7 3.3 0.19 11.8 0.2 2.9 2 1 1 3 3 3 0 Acetyl-coA carboxylase zinc finger domain ATE_N PF04376.13 KXZ51774.1 - 0.058 13.8 0.5 0.4 11.1 0.0 2.2 1 1 1 2 2 2 0 Arginine-tRNA-protein transferase, N terminus DZR PF12773.7 KXZ51774.1 - 0.061 13.3 3.0 0.37 10.9 1.8 2.2 1 1 2 3 3 3 0 Double zinc ribbon NinF PF05810.12 KXZ51774.1 - 0.11 12.4 0.0 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 NinF protein Yippee-Mis18 PF03226.14 KXZ51774.1 - 0.13 12.4 0.7 0.77 10.0 0.7 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.6 KXZ51774.1 - 0.69 9.4 6.6 4.1 7.0 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Steroid_dh PF02544.16 KXZ51775.1 - 5.5e-31 107.6 1.7 5.5e-31 107.6 1.7 2.0 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KXZ51775.1 - 1.6e-06 27.7 0.0 5.6e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXZ51775.1 - 0.0054 17.2 0.0 0.0092 16.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KXZ51775.1 - 0.12 12.4 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Ank_2 PF12796.7 KXZ51776.1 - 3.7e-09 37.0 5.9 0.0059 17.2 0.2 4.2 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51776.1 - 6.4e-05 23.4 9.7 0.76 10.4 0.3 6.0 4 3 3 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51776.1 - 0.00047 20.4 6.7 39 5.3 0.0 7.3 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ51776.1 - 8 6.9 8.3 54 4.3 0.1 4.8 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Peptidase_M22 PF00814.25 KXZ51777.1 - 1.4e-66 225.0 0.1 2.6e-44 152.0 0.0 2.1 2 0 0 2 2 2 2 Glycoprotease family Carbam_trans_N PF02543.15 KXZ51777.1 - 0.0026 17.5 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Bac_globin PF01152.21 KXZ51779.1 - 2e-16 60.2 0.0 2.4e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin TPR_5 PF12688.7 KXZ51779.1 - 0.063 13.5 0.0 0.088 13.1 0.0 1.2 1 0 0 1 1 1 0 Tetratrico peptide repeat DUF4487 PF14868.6 KXZ51781.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) VCBS PF13517.6 KXZ51782.1 - 6.4e-05 23.5 0.2 6.7 7.4 0.0 3.5 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF1883 PF08980.10 KXZ51782.1 - 9.1e-05 22.3 2.3 29 4.7 0.0 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF1883) EF-hand_1 PF00036.32 KXZ51782.1 - 0.0026 17.2 1.3 6.1 6.6 0.0 3.1 3 0 0 3 3 3 2 EF hand LSM_int_assoc PF16605.5 KXZ51782.1 - 0.07 13.3 0.0 22 5.3 0.0 3.7 5 0 0 5 5 5 0 LSM-interacting associated unstructured EF-hand_6 PF13405.6 KXZ51782.1 - 0.68 10.0 2.2 74 3.7 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain Zea_mays_MuDR PF05928.11 KXZ51782.1 - 7.6 6.1 9.1 10 5.7 9.1 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) RPE65 PF03055.15 KXZ51783.1 - 6e-81 273.0 0.0 7.4e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 KXZ51784.1 - 3.1e-25 89.3 0.0 3.7e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FAST_1 PF06743.15 KXZ51785.1 - 1.4e-15 57.0 0.5 0.013 15.4 0.0 6.4 6 1 1 7 7 7 5 FAST kinase-like protein, subdomain 1 Ank_4 PF13637.6 KXZ51786.1 - 0.00059 20.3 0.2 0.0035 17.9 0.1 2.2 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51786.1 - 0.0023 18.3 1.5 13 6.8 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KXZ51786.1 - 0.0033 18.0 0.2 0.011 16.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PCRF PF03462.18 KXZ51788.1 - 0.13 12.1 6.1 0.16 11.8 6.1 1.1 1 0 0 1 1 1 0 PCRF domain YjcZ PF13990.6 KXZ51788.1 - 0.19 11.1 3.9 0.21 10.9 3.9 1.2 1 0 0 1 1 1 0 YjcZ-like protein FAM76 PF16046.5 KXZ51788.1 - 0.22 10.8 7.0 0.26 10.6 7.0 1.1 1 0 0 1 1 1 0 FAM76 protein Glyco_trans_1_2 PF13524.6 KXZ51788.1 - 0.34 11.3 8.2 1.7 9.1 0.5 2.2 1 1 1 2 2 2 0 Glycosyl transferases group 1 SecM PF06558.12 KXZ51788.1 - 1.8 8.6 4.4 6.1 6.9 2.1 2.3 1 1 2 3 3 3 0 Secretion monitor precursor protein (SecM) DUF5401 PF17380.2 KXZ51788.1 - 8.9 4.2 18.0 10 4.0 18.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Acetyltransf_1 PF00583.25 KXZ51789.1 - 3.2e-10 40.3 0.0 3.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ51789.1 - 1.5e-06 28.5 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ51789.1 - 3.3e-06 27.0 0.0 6.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KXZ51789.1 - 1.2e-05 25.3 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Prefoldin_2 PF01920.20 KXZ51791.1 - 0.057 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit Ank_2 PF12796.7 KXZ51792.1 - 4.9e-08 33.5 0.6 0.25 12.0 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ51792.1 - 8.2e-08 32.4 1.3 0.054 13.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ51792.1 - 3.2e-05 24.4 2.2 3.7 8.3 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51792.1 - 0.00034 20.8 7.7 0.9 10.3 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXZ51792.1 - 0.001 19.4 12.0 0.11 12.9 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KXZ51793.1 - 7e-47 157.9 0.0 5.5e-11 42.9 0.0 7.3 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ51793.1 - 3.4e-42 141.9 9.2 5.3e-08 33.0 0.0 10.6 7 4 4 11 11 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ51793.1 - 3.6e-42 142.2 5.4 6.6e-08 33.0 0.0 9.5 7 3 3 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51793.1 - 4.1e-35 118.7 21.4 2.2e-05 24.7 0.0 12.5 11 1 0 11 11 11 7 Ankyrin repeat Ank_3 PF13606.6 KXZ51793.1 - 7.7e-35 115.0 10.2 0.0028 18.0 0.0 13.3 15 0 0 15 15 15 7 Ankyrin repeat tRNA-synt_1c PF00749.21 KXZ51794.1 - 7.4e-110 366.7 0.0 1.4e-109 365.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KXZ51794.1 - 1e-50 171.9 2.2 3.6e-40 137.6 0.2 2.2 1 1 1 2 2 2 2 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KXZ51794.1 - 1.3e-40 139.2 0.0 2.7e-40 138.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KXZ51794.1 - 5.3e-08 33.7 0.3 1.2e-07 32.6 0.3 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ribosomal_S2 PF00318.20 KXZ51795.1 - 1.1e-11 44.5 0.0 2.2e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S2 RBP_receptor PF14752.6 KXZ51796.1 - 0.092 11.3 12.5 0.18 10.3 12.5 1.4 1 0 0 1 1 1 0 Retinol binding protein receptor BACK PF07707.15 KXZ51797.1 - 0.00024 21.1 0.0 0.00063 19.8 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BACK PF07707.15 KXZ51798.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.6 1 1 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ51798.1 - 0.0093 16.2 0.0 0.93 9.7 0.0 2.8 3 0 0 3 3 3 1 BTB/POZ domain BACK PF07707.15 KXZ51799.1 - 7e-07 29.3 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank_2 PF12796.7 KXZ51800.1 - 1.4e-16 60.8 4.6 6.2e-06 26.7 0.0 6.7 3 3 4 8 8 8 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51800.1 - 2.2e-12 47.2 17.6 0.067 13.8 0.1 9.4 8 2 3 11 11 11 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51800.1 - 1.7e-05 24.8 5.0 3.9 8.3 0.0 8.7 10 0 0 10 10 10 1 Ankyrin repeat F-box-like PF12937.7 KXZ51800.1 - 0.018 14.9 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 F-box-like HTH_39 PF14090.6 KXZ51800.1 - 0.023 14.4 0.0 0.35 10.6 0.0 3.0 4 0 0 4 4 4 0 Helix-turn-helix domain DUF4224 PF13986.6 KXZ51800.1 - 0.067 13.1 2.2 17 5.4 0.0 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF4224) Nif11 PF07862.11 KXZ51800.1 - 0.23 11.8 1.4 12 6.3 0.0 3.5 3 0 0 3 3 3 0 Nif11 domain SNF2_N PF00176.23 KXZ51801.1 - 1.4e-67 227.9 0.0 2.3e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXZ51801.1 - 5.6e-16 58.2 0.1 2.2e-15 56.4 0.1 1.9 1 1 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXZ51801.1 - 1.1e-11 45.0 0.0 2.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KXZ51801.1 - 1.9e-08 34.0 4.8 3.5e-08 33.2 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ51801.1 - 2e-08 34.4 5.9 3.8e-08 33.5 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXZ51801.1 - 3e-08 33.5 4.0 5.3e-08 32.7 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ51801.1 - 5.6e-08 32.5 4.7 1e-07 31.7 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ51801.1 - 3e-07 30.2 6.2 6.2e-07 29.2 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ51801.1 - 1.6e-05 24.8 7.0 3.8e-05 23.6 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXZ51801.1 - 4.4e-05 23.2 4.7 0.00012 21.8 4.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXZ51801.1 - 0.00031 20.7 0.3 0.0006 19.8 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXZ51801.1 - 0.0014 18.9 1.8 0.0028 17.9 1.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain FF PF01846.19 KXZ51801.1 - 0.0047 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 FF domain ResIII PF04851.15 KXZ51801.1 - 0.0058 16.7 0.0 0.09 12.8 0.0 2.4 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXZ51801.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_6 PF14835.6 KXZ51801.1 - 0.019 14.8 3.0 0.048 13.5 3.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KXZ51801.1 - 0.022 14.9 6.8 0.044 13.9 6.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KXZ51801.1 - 0.027 14.3 1.5 0.065 13.1 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FoP_duplication PF13865.6 KXZ51801.1 - 0.032 14.8 0.7 0.032 14.8 0.7 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 zf-RING_4 PF14570.6 KXZ51801.1 - 0.14 12.0 5.2 0.31 10.9 5.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KXZ51801.1 - 0.15 11.8 2.5 0.28 11.0 2.5 1.5 1 0 0 1 1 1 0 RING-like zinc finger PH PF00169.29 KXZ51802.1 - 3.3e-15 56.5 0.0 4.1e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KXZ51802.1 - 0.00017 21.9 0.7 0.00093 19.6 0.7 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KXZ51802.1 - 0.00023 21.5 0.0 0.00027 21.3 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KXZ51802.1 - 0.0057 16.7 0.1 0.0079 16.3 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KXZ51802.1 - 0.0082 16.0 0.0 0.0085 15.9 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KXZ51802.1 - 0.017 15.4 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_6 PF15406.6 KXZ51802.1 - 0.022 15.1 0.2 0.037 14.3 0.2 1.4 1 1 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 KXZ51802.1 - 0.07 13.4 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain HOOK PF05622.12 KXZ51803.1 - 0.00051 18.3 4.3 0.00061 18.1 4.3 1.2 1 0 0 1 1 1 1 HOOK protein TSC22 PF01166.18 KXZ51803.1 - 0.0036 17.6 6.7 0.017 15.5 0.4 2.9 1 1 2 3 3 3 1 TSC-22/dip/bun family Miff PF05644.11 KXZ51803.1 - 0.013 15.2 0.8 0.013 15.2 0.8 1.6 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff DUF812 PF05667.11 KXZ51803.1 - 0.021 13.7 3.6 0.023 13.6 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YabA PF06156.13 KXZ51803.1 - 0.023 15.3 1.7 0.1 13.2 0.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Herpes_BLRF2 PF05812.12 KXZ51803.1 - 0.067 13.3 1.7 0.56 10.4 1.6 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF2312 PF10073.9 KXZ51803.1 - 0.11 12.2 0.3 0.11 12.2 0.3 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) GAS PF13851.6 KXZ51803.1 - 0.3 10.4 4.9 0.47 9.8 4.4 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 KXZ51803.1 - 0.3 11.5 13.1 0.7 10.4 1.9 2.8 1 1 2 3 3 3 0 Cell division protein ZapB ATG16 PF08614.11 KXZ51803.1 - 0.35 11.1 20.6 1.9 8.7 8.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) LEH PF07858.12 KXZ51803.1 - 0.57 10.3 4.7 0.85 9.7 4.5 1.4 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain dCMP_cyt_deam_1 PF00383.23 KXZ51803.1 - 0.85 9.5 3.6 1.5 8.7 3.6 1.5 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region bZIP_1 PF00170.21 KXZ51803.1 - 3.2 7.9 8.1 2.2 8.4 1.1 3.1 2 1 1 3 3 3 0 bZIP transcription factor BACK PF07707.15 KXZ51804.1 - 2.2e-06 27.7 0.1 3.9e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF4231 PF14015.6 KXZ51804.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) BACK PF07707.15 KXZ51805.1 - 1.4e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BACK PF07707.15 KXZ51806.1 - 7.5e-06 26.0 0.1 1.2e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch IMPDH PF00478.25 KXZ51807.1 - 3.6e-127 424.1 7.1 4.2e-127 423.9 7.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KXZ51807.1 - 4.9e-12 46.1 0.0 4e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KXZ51807.1 - 1.7e-10 40.5 4.2 3.3e-10 39.5 4.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KXZ51807.1 - 3e-10 40.0 7.6 1.9e-07 30.8 5.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KXZ51807.1 - 0.00017 21.1 4.0 0.00024 20.6 1.8 2.2 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KXZ51807.1 - 0.00036 19.9 3.4 0.0009 18.6 3.4 1.7 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG EAL PF00563.20 KXZ51807.1 - 0.005 16.4 0.7 0.51 9.8 0.1 2.3 2 0 0 2 2 2 1 EAL domain IGPS PF00218.21 KXZ51807.1 - 0.01 15.0 0.0 0.27 10.3 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.12 KXZ51807.1 - 0.043 13.2 1.0 0.08 12.4 0.1 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 KXZ51807.1 - 0.046 12.8 3.3 0.21 10.6 0.1 2.5 1 1 1 3 3 3 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KXZ51807.1 - 0.41 9.8 4.7 0.11 11.7 0.5 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Steroid_dh PF02544.16 KXZ51808.1 - 3.8e-22 78.9 0.3 3.8e-20 72.4 0.0 3.1 4 0 0 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KXZ51808.1 - 0.0033 17.8 0.1 0.0033 17.8 0.1 3.0 4 0 0 4 4 4 1 Phospholipid methyltransferase Rab5ip PF07019.12 KXZ51809.1 - 4.1e-12 46.5 12.0 4.8e-12 46.3 12.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_21 PF09976.9 KXZ51809.1 - 0.05 13.3 0.2 0.071 12.8 0.2 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain zf-HC5HC2H_2 PF13832.6 KXZ51810.1 - 2.8e-22 79.0 5.3 2.8e-22 79.0 5.3 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXZ51810.1 - 2.6e-14 53.2 7.6 3.6e-14 52.8 1.4 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KXZ51810.1 - 2.7e-10 39.6 3.0 2.7e-10 39.6 3.0 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXZ51810.1 - 2.4e-08 33.7 13.0 1.2e-07 31.4 4.2 2.7 2 0 0 2 2 2 2 PHD-finger Ada3 PF10198.9 KXZ51810.1 - 1.1e-07 32.1 1.5 6.2e-07 29.6 1.5 2.3 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 C1_1 PF00130.22 KXZ51810.1 - 0.02 14.7 6.0 0.033 14.1 0.2 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 KXZ51810.1 - 0.16 12.2 0.9 0.45 10.7 0.9 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DDOST_48kD PF03345.14 KXZ51811.1 - 9.2e-110 367.3 0.0 1.1e-109 367.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF5060 PF16586.5 KXZ51811.1 - 0.016 15.6 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5060) ABC_tran PF00005.27 KXZ51812.1 - 6.1e-24 85.1 0.0 1.1e-23 84.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXZ51812.1 - 5.8e-22 78.3 10.6 8.3e-22 77.8 10.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXZ51812.1 - 2e-10 41.0 0.0 6.7e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 KXZ51812.1 - 7.2e-08 32.1 22.5 7.5e-06 25.5 17.0 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_23 PF13476.6 KXZ51812.1 - 0.00019 22.0 0.3 0.00033 21.2 0.3 1.3 1 0 0 1 1 1 1 AAA domain HicA_toxin PF07927.12 KXZ51813.1 - 0.0035 17.3 0.1 0.013 15.5 0.1 2.0 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, PDCD2_C PF04194.13 KXZ51815.1 - 3.5e-23 82.6 0.0 5.7e-22 78.6 0.0 2.3 1 1 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain FCP1_C PF09309.10 KXZ51815.1 - 0.35 10.7 6.0 0.65 9.8 6.0 1.3 1 0 0 1 1 1 0 FCP1, C-terminal ANAPC_CDC26 PF10471.9 KXZ51815.1 - 2.6 8.9 14.2 0.29 12.0 5.6 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 UCH PF00443.29 KXZ51816.1 - 5.3e-35 121.2 0.0 4.1e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ51816.1 - 3.2e-12 46.7 0.0 1.3e-06 28.3 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Aminotran_1_2 PF00155.21 KXZ51817.1 - 2.2e-13 50.1 0.0 8.1e-08 31.8 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Lant_dehydr_C PF14028.6 KXZ51817.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term EamA PF00892.20 KXZ51818.1 - 1.3e-06 28.7 22.0 0.0014 18.8 1.4 3.4 3 0 0 3 3 3 3 EamA-like transporter family NYD-SP28 PF14772.6 KXZ51819.1 - 5.8e-19 68.0 13.8 5.8e-19 68.0 13.8 4.5 2 2 0 3 3 3 1 Sperm tail NYD-SP28_assoc PF14775.6 KXZ51819.1 - 1.1e-10 41.5 1.1 1.1e-10 41.5 1.1 2.7 2 0 0 2 2 2 1 Sperm tail C-terminal domain Flu_B_M2 PF04772.12 KXZ51819.1 - 0.014 15.6 0.9 0.034 14.4 0.9 1.6 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) MAAL_C PF07476.11 KXZ51819.1 - 0.44 9.6 4.7 0.093 11.9 1.0 1.7 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Ank_2 PF12796.7 KXZ51821.1 - 2.5e-09 37.6 0.0 9.8e-06 26.1 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51821.1 - 1.9e-07 31.5 3.4 0.024 15.2 1.1 4.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51821.1 - 8.7e-07 28.8 0.5 0.11 13.1 0.0 4.9 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KXZ51821.1 - 0.016 15.5 0.6 23 5.5 0.1 3.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51821.1 - 0.18 12.3 0.4 2.2 8.9 0.1 2.6 3 0 0 3 3 3 0 Ankyrin repeat PDDEXK_6 PF04720.12 KXZ51822.1 - 7.8e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 PDDEXK-like family of unknown function Peptidase_M10 PF00413.24 KXZ51823.1 - 1.5e-30 106.2 0.0 1.3e-29 103.1 0.0 2.1 2 0 0 2 2 2 1 Matrixin Tyrosinase PF00264.20 KXZ51823.1 - 5.5e-30 105.3 3.6 1e-27 97.9 3.6 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase PG_binding_1 PF01471.18 KXZ51823.1 - 3.9e-21 75.0 0.1 9.1e-21 73.8 0.1 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain EF-hand_1 PF00036.32 KXZ51823.1 - 2.5e-06 26.6 0.0 0.00031 20.1 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXZ51823.1 - 3.1e-06 27.5 0.0 7.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ51823.1 - 5.7e-06 26.1 0.0 0.0018 18.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ51823.1 - 4.8e-05 22.7 0.0 0.00021 20.6 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ51823.1 - 7.4e-05 22.4 0.0 0.0018 18.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain Reprolysin_5 PF13688.6 KXZ51823.1 - 0.0028 17.8 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 PG_binding_2 PF08823.11 KXZ51823.1 - 0.0063 16.8 0.2 0.036 14.4 0.1 2.1 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 KXZ51823.1 - 0.0075 16.5 0.0 1.5 9.1 0.0 2.8 1 1 1 2 2 2 1 Predicted Peptidoglycan domain Peptidase_M54 PF07998.11 KXZ51823.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 KXZ51823.1 - 0.06 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 KXZ51823.1 - 0.091 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.5 KXZ51823.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 KXZ51823.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KXZ51823.1 - 0.25 10.9 0.1 0.58 9.7 0.1 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Ribosomal_L34 PF00468.17 KXZ51825.1 - 4.7e-16 58.5 6.4 5.9e-16 58.2 6.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L34 CN_hydrolase PF00795.22 KXZ51826.1 - 1.1e-31 110.2 0.1 1.3e-31 109.9 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CSN8_PSD8_EIF3K PF10075.9 KXZ51827.1 - 7.7e-21 74.6 0.0 3.8e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family adh_short PF00106.25 KXZ51828.1 - 1e-34 119.7 0.1 1.5e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ51828.1 - 2e-32 112.6 0.6 2.8e-32 112.2 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 KXZ51828.1 - 0.01 16.4 0.1 0.025 15.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent HAD PF12710.7 KXZ51828.1 - 0.014 15.8 0.2 0.035 14.5 0.2 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ATP-synt_ab PF00006.25 KXZ51828.1 - 0.02 14.5 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Amidohydro_2 PF04909.14 KXZ51828.1 - 0.029 14.1 0.2 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 Amidohydrolase Myb_DNA-binding PF00249.31 KXZ51829.1 - 0.0002 21.5 0.1 0.00052 20.1 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ51829.1 - 0.017 15.3 0.2 0.039 14.2 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain ANAPC_CDC26 PF10471.9 KXZ51829.1 - 3.8 8.4 13.2 0.065 14.1 4.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Ank_2 PF12796.7 KXZ51830.1 - 9.8e-09 35.7 0.2 0.0013 19.3 0.0 4.6 2 1 3 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51830.1 - 1e-08 35.6 9.7 1.8 9.2 0.2 7.7 6 2 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51830.1 - 5.6e-05 23.2 1.8 1.7e+02 3.4 0.0 7.6 9 0 0 9 9 9 0 Ankyrin repeat Ferric_reduct PF01794.19 KXZ51832.1 - 0.00029 20.9 0.8 0.0074 16.4 0.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Cytochrom_B561 PF03188.16 KXZ51832.1 - 0.00077 19.6 3.9 0.013 15.7 1.2 2.1 1 1 0 2 2 2 2 Eukaryotic cytochrome b561 FtsK_4TM PF13491.6 KXZ51832.1 - 0.23 11.1 4.1 4.5 6.9 0.1 2.1 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DOMON PF03351.17 KXZ51833.1 - 2.8e-07 30.8 0.0 5.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXZ51833.1 - 0.002 18.3 3.4 0.002 18.3 3.4 2.4 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KXZ51833.1 - 1.6 8.5 6.1 1.8 8.4 0.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF2427) DOMON PF03351.17 KXZ51834.1 - 3.9e-08 33.5 0.0 8.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXZ51834.1 - 6.1e-05 23.2 7.6 0.00077 19.6 4.2 3.0 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 KXZ51834.1 - 0.023 14.8 1.5 0.023 14.8 1.5 2.3 2 0 0 2 2 2 0 Ferric reductase like transmembrane component DUF2427 PF10348.9 KXZ51834.1 - 0.3 10.9 3.2 2 8.2 0.0 3.4 3 1 2 5 5 5 0 Domain of unknown function (DUF2427) MRI PF15325.6 KXZ51834.1 - 1.9 9.6 5.5 6.7 7.9 3.6 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection MOZART1 PF12554.8 KXZ51836.1 - 1.2e-17 63.4 0.3 1.6e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.7 KXZ51836.1 - 0.096 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated COBRA1 PF06209.13 KXZ51837.1 - 7.5e-38 130.6 0.0 5.6e-16 58.5 0.0 3.2 3 0 0 3 3 3 3 Cofactor of BRCA1 (COBRA1) ABC_tran PF00005.27 KXZ51841.1 - 0.0081 16.7 0.0 0.0099 16.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter NCA2 PF08637.10 KXZ51842.1 - 9e-41 139.9 0.0 1e-29 103.6 0.0 2.0 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 Ank_2 PF12796.7 KXZ51843.1 - 2.7e-13 50.3 3.3 7.7e-05 23.2 0.1 3.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51843.1 - 2.1e-07 31.4 10.8 0.61 10.7 1.0 6.8 3 3 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51843.1 - 0.0007 19.9 9.6 11 6.9 0.0 7.6 7 2 2 9 9 9 1 Ankyrin repeat Zip PF02535.22 KXZ51844.1 - 3e-18 66.2 5.3 1.5e-09 37.5 1.5 3.2 3 0 0 3 3 3 3 ZIP Zinc transporter Neur_chan_memb PF02932.16 KXZ51845.1 - 0.44 10.6 4.0 0.71 9.9 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 KXZ51845.1 - 2 8.3 15.1 3.5 7.5 15.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXZ51845.1 - 6.7 6.3 8.9 10 5.7 8.9 1.2 1 0 0 1 1 1 0 Spt20 family Ank_2 PF12796.7 KXZ51847.1 - 1.6e-13 51.1 0.0 0.0025 18.4 0.0 3.7 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51847.1 - 8.6e-12 45.3 3.5 0.00085 19.8 0.0 6.7 5 1 3 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51847.1 - 4.2e-06 26.7 0.0 26 5.8 0.0 7.3 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ51847.1 - 0.00089 19.5 4.3 9.6 6.7 0.1 5.7 3 1 2 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51848.1 - 4.5e-18 65.6 0.0 4e-07 30.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51848.1 - 6.1e-10 39.4 5.3 0.096 13.3 0.7 7.0 4 3 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51848.1 - 1.1e-09 37.8 0.0 0.98 10.2 0.0 7.6 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KXZ51848.1 - 0.00018 21.7 0.6 0.61 10.5 0.0 5.4 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51848.1 - 0.0045 17.4 0.9 5.9 7.5 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 KXZ51850.1 - 1.8e-15 57.0 0.6 0.0086 16.6 0.2 6.2 5 2 0 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51850.1 - 5.1e-15 55.8 0.0 0.0005 20.6 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ51850.1 - 1.1e-09 37.7 0.1 0.022 15.3 0.0 7.2 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ51850.1 - 5.7e-05 23.3 3.3 0.015 15.6 0.0 4.9 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ51850.1 - 0.00035 20.9 0.4 3.5 8.2 0.1 4.0 6 0 0 6 6 6 2 Ankyrin repeat DUF4224 PF13986.6 KXZ51850.1 - 0.029 14.3 2.6 59 3.7 0.0 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF4224) Pox_A_type_inc PF04508.12 KXZ51850.1 - 0.17 11.8 0.5 0.37 10.7 0.5 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Glyoxalase_4 PF13669.6 KXZ51850.1 - 0.27 11.5 1.2 5.1 7.4 0.1 3.3 3 1 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ABC2_membrane_3 PF12698.7 KXZ51851.1 - 6.1e-17 61.7 17.9 1e-16 61.0 17.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KXZ51851.1 - 1.3e-12 48.4 0.0 2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KXZ51851.1 - 0.24 11.9 0.2 0.39 11.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KXZ51851.1 - 0.95 8.7 10.5 1.8 7.8 10.5 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Ank_2 PF12796.7 KXZ51852.1 - 4.5e-15 56.0 0.0 1.7e-06 28.5 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51852.1 - 4.2e-08 33.6 5.2 0.11 13.1 0.2 5.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51852.1 - 2.8e-05 24.2 0.0 1.6 9.6 0.0 6.7 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ51852.1 - 0.00022 21.4 0.0 0.63 10.4 0.0 4.5 3 2 2 5 5 5 1 Ankyrin repeats (many copies) VHP PF02209.19 KXZ51854.1 - 1.5e-10 40.9 0.2 2.3e-10 40.3 0.2 1.3 1 0 0 1 1 1 1 Villin headpiece domain DUF2793 PF10983.8 KXZ51854.1 - 0.0068 16.3 0.4 0.017 15.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2793) adh_short PF00106.25 KXZ51855.1 - 1.6e-31 109.3 4.0 2.3e-30 105.5 4.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ51855.1 - 3e-25 89.2 2.0 6.2e-25 88.1 2.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ51855.1 - 1.5e-11 44.6 0.4 3.5e-11 43.3 0.3 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXZ51855.1 - 0.0014 18.1 0.6 0.0066 15.9 0.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXZ51855.1 - 0.039 13.3 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KXZ51855.1 - 0.097 12.5 0.4 0.16 11.8 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KXZ51856.1 - 1.7e-37 129.3 0.0 2.9e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ51856.1 - 1.7e-11 44.5 0.2 2e-10 41.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_5 PF13202.6 KXZ51856.1 - 6e-06 25.5 0.0 1.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ51856.1 - 3.1e-05 23.2 0.0 0.0001 21.6 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXZ51856.1 - 0.0015 18.3 0.1 0.0078 16.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain DAO PF01266.24 KXZ51856.1 - 0.002 17.8 1.6 0.021 14.4 0.0 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase EF-hand_7 PF13499.6 KXZ51856.1 - 0.015 15.7 0.1 0.035 14.6 0.1 1.6 1 1 0 1 1 1 0 EF-hand domain pair Pyr_redox_3 PF13738.6 KXZ51856.1 - 0.082 12.2 0.3 0.22 10.7 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 KXZ51856.1 - 0.087 12.7 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_10 PF14788.6 KXZ51856.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 EF hand Arm PF00514.23 KXZ51858.1 - 4.7e-10 39.2 4.7 0.42 10.7 0.0 4.9 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXZ51858.1 - 3e-05 24.3 3.0 3e-05 24.3 3.0 4.0 1 1 3 4 4 4 2 HEAT repeats HEAT PF02985.22 KXZ51858.1 - 0.0034 17.5 4.7 0.53 10.7 0.2 4.2 4 0 0 4 4 4 2 HEAT repeat Tti2 PF10521.9 KXZ51858.1 - 0.26 10.8 0.0 5 6.6 0.0 2.1 1 1 1 2 2 2 0 Tti2 family MatE PF01554.18 KXZ51860.1 - 1.4e-36 125.6 21.0 3e-22 79.0 9.9 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ51860.1 - 1 9.5 26.0 0.22 11.6 0.6 4.2 2 1 2 4 4 4 0 Polysaccharide biosynthesis C-terminal domain DUF2304 PF10066.9 KXZ51860.1 - 8.1 6.7 7.8 6.2 7.1 0.8 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) DUF981 PF06168.11 KXZ51861.1 - 0.2 11.5 4.4 0.32 10.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Nop16 PF09420.10 KXZ51862.1 - 4.9e-22 79.0 10.5 2.3e-15 57.2 0.2 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 DUF1126 PF06565.12 KXZ51864.1 - 4e-58 193.7 0.0 4.5e-22 77.9 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain mTERF PF02536.14 KXZ51865.1 - 1e-11 44.4 0.0 1.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 mTERF LSM PF01423.22 KXZ51866.1 - 9.5e-17 60.5 0.1 1.2e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Ank_2 PF12796.7 KXZ51869.1 - 2.6e-10 40.8 0.0 0.29 11.7 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ51869.1 - 3.4e-10 40.2 2.5 0.45 11.2 0.1 6.4 5 2 1 6 6 6 4 Ankyrin repeats (many copies) CobT PF06213.12 KXZ51869.1 - 0.086 12.2 11.5 0.15 11.5 11.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ank_5 PF13857.6 KXZ51869.1 - 1.5 9.2 9.8 96 3.5 0.0 6.2 6 2 2 8 8 8 0 Ankyrin repeats (many copies) Paf1 PF03985.13 KXZ51869.1 - 1.9 7.4 14.3 2.7 6.9 14.3 1.1 1 0 0 1 1 1 0 Paf1 HALZ PF02183.18 KXZ51870.1 - 0.0015 18.7 24.7 0.57 10.4 0.1 6.9 6 0 0 6 6 6 4 Homeobox associated leucine zipper Proteasome PF00227.26 KXZ51871.1 - 4.1e-36 124.2 0.0 5.1e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF563 PF04577.14 KXZ51872.1 - 1.8e-28 100.1 0.0 2.3e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ephrin_rec_like PF07699.13 KXZ51872.1 - 8.8e-06 25.4 17.0 8.4e-05 22.3 5.4 2.4 1 1 1 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 KXZ51872.1 - 0.0014 18.6 7.4 0.21 11.6 0.4 2.4 2 0 0 2 2 2 2 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KXZ51872.1 - 1.7 9.1 11.1 0.36 11.3 1.0 3.0 3 1 0 3 3 3 0 TNFR/NGFR cysteine-rich region FAD_binding_4 PF01565.23 KXZ51873.1 - 1.6e-12 47.4 0.1 4.8e-10 39.3 0.0 2.6 2 0 0 2 2 2 2 FAD binding domain Cluap1 PF10234.9 KXZ51874.1 - 1.8e-101 339.0 5.1 1.8e-101 339.0 5.1 1.4 1 1 0 1 1 1 1 Clusterin-associated protein-1 Lebercilin PF15619.6 KXZ51874.1 - 2.2e-05 24.2 21.8 3.5e-05 23.6 21.8 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 KXZ51874.1 - 0.00014 22.3 1.4 0.00014 22.3 1.4 2.8 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein Herpes_UL6 PF01763.16 KXZ51874.1 - 0.0032 16.1 1.0 0.0032 16.1 1.0 1.4 1 1 0 1 1 1 1 Herpesvirus UL6 like Prefoldin_2 PF01920.20 KXZ51874.1 - 0.0044 17.0 6.6 0.0044 17.0 6.6 3.5 2 1 2 4 4 4 1 Prefoldin subunit Lectin_N PF03954.14 KXZ51874.1 - 0.0063 16.3 6.7 0.27 11.0 0.8 2.3 2 0 0 2 2 2 2 Hepatic lectin, N-terminal domain Cas_Csa4 PF09703.10 KXZ51874.1 - 0.0087 15.4 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csa4) Exonuc_VII_L PF02601.15 KXZ51874.1 - 0.015 14.9 8.4 0.024 14.2 8.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 KXZ51874.1 - 0.016 13.8 10.2 0.019 13.6 10.2 1.1 1 0 0 1 1 1 0 Macoilin family DASH_Spc19 PF08287.11 KXZ51874.1 - 0.019 14.9 23.4 0.05 13.5 9.3 2.4 1 1 1 2 2 2 0 Spc19 DUF4795 PF16043.5 KXZ51874.1 - 0.027 14.1 14.3 0.049 13.2 14.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Fez1 PF06818.15 KXZ51874.1 - 0.074 13.5 17.8 0.13 12.7 17.8 1.4 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 KXZ51874.1 - 0.7 8.7 24.2 0.88 8.4 15.3 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 KXZ51874.1 - 0.89 10.1 29.4 0.05 14.1 11.4 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region HrpB7 PF09486.10 KXZ51874.1 - 0.96 9.8 14.8 2.2 8.7 14.8 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) STAT_alpha PF01017.20 KXZ51874.1 - 3.1 7.7 14.1 0.099 12.5 6.3 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain Prefoldin PF02996.17 KXZ51874.1 - 3.3 7.6 16.7 0.16 11.9 6.3 3.1 2 1 1 3 3 3 0 Prefoldin subunit DUF5082 PF16888.5 KXZ51874.1 - 4.1 7.7 16.0 0.07 13.4 5.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DASH_Dam1 PF08653.10 KXZ51874.1 - 5.5 6.9 5.3 1.3 8.9 0.4 2.6 3 0 0 3 3 2 0 DASH complex subunit Dam1 CREPT PF16566.5 KXZ51874.1 - 6.4 6.9 17.2 0.47 10.6 6.8 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4407 PF14362.6 KXZ51874.1 - 8.2 5.7 14.6 20 4.4 14.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1168 PF06658.12 KXZ51874.1 - 8.5 6.2 17.3 0.17 11.7 5.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) FlxA PF14282.6 KXZ51874.1 - 9.2 6.3 13.4 0.39 10.7 5.2 2.3 2 0 0 2 2 2 0 FlxA-like protein PAP_fibrillin PF04755.12 KXZ51875.1 - 2.7e-34 118.9 0.0 5e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 PAP_fibrillin DUF5094 PF17015.5 KXZ51876.1 - 0.16 12.1 1.3 0.21 11.7 0.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) BLOC1_2 PF10046.9 KXZ51876.1 - 2.5 8.4 12.3 1.9 8.9 0.1 3.9 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KXZ51876.1 - 5.4 7.3 8.4 9.2 6.6 0.6 3.3 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PAP_fibrillin PF04755.12 KXZ51877.1 - 5.9e-34 117.7 0.0 1.1e-33 116.8 0.0 1.5 1 0 0 1 1 1 1 PAP_fibrillin LysM PF01476.20 KXZ51877.1 - 0.021 14.9 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 LysM domain EMP70 PF02990.16 KXZ51878.1 - 6.2e-161 536.6 14.4 8.1e-161 536.2 14.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 KXZ51878.1 - 0.0047 15.9 12.5 0.0047 15.9 12.5 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MWFE PF15879.5 KXZ51878.1 - 0.087 13.0 2.6 0.12 12.5 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit PPR PF01535.20 KXZ51879.1 - 0.095 13.0 0.2 29 5.2 0.0 2.9 3 0 0 3 3 3 0 PPR repeat 3-alpha PF03475.14 KXZ51879.1 - 1 9.3 5.2 1.4 8.8 3.1 2.3 2 0 0 2 2 2 0 3-alpha domain Pkinase PF00069.25 KXZ51880.1 - 2.4e-43 148.4 0.2 1.9e-39 135.6 0.1 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ51880.1 - 1.4e-25 90.1 0.0 3.3e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KXZ51880.1 - 0.00033 21.0 0.6 0.00033 21.0 0.6 5.7 6 0 0 6 6 6 2 HEAT repeats Kinase-like PF14531.6 KXZ51880.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RICTOR_N PF14664.6 KXZ51880.1 - 0.019 13.9 3.0 1 8.3 0.0 3.0 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term TFCD_C PF12612.8 KXZ51880.1 - 0.024 14.5 1.2 8.4 6.2 0.0 3.9 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal Gcn1_N PF12074.8 KXZ51880.1 - 0.08 12.2 0.0 4.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KXZ51880.1 - 0.083 13.2 20.8 0.11 12.8 0.0 9.2 10 0 0 10 10 10 0 HEAT repeat Sec7_N PF12783.7 KXZ51880.1 - 0.092 12.6 6.7 0.31 11.0 0.0 4.4 6 1 1 7 7 7 0 Guanine nucleotide exchange factor in Golgi transport N-terminal APH PF01636.23 KXZ51880.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.3 5 0 0 5 5 5 0 Phosphotransferase enzyme family CLASP_N PF12348.8 KXZ51880.1 - 0.13 11.8 5.1 0.28 10.7 0.3 2.9 3 0 0 3 3 3 0 CLASP N terminal Arm PF00514.23 KXZ51880.1 - 1.3 9.2 0.0 1.3 9.2 0.0 6.3 10 0 0 10 10 9 0 Armadillo/beta-catenin-like repeat Polbeta PF18765.1 KXZ51881.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KXZ51881.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain phage_tail_N PF08400.10 KXZ51882.1 - 0.16 11.9 0.2 0.27 11.2 0.2 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Prenyltrans PF00432.21 KXZ51883.1 - 6.5e-43 144.2 13.0 2.1e-10 40.1 0.7 5.7 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Lipase_GDSL_2 PF13472.6 KXZ51884.1 - 9.9e-07 29.3 0.0 1.5e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Apis_Csd PF11671.8 KXZ51884.1 - 4 7.5 4.4 0.92 9.5 0.4 1.9 2 0 0 2 2 2 0 Complementary sex determiner protein Vinculin PF01044.19 KXZ51885.1 - 0.073 11.3 0.0 0.077 11.2 0.0 1.0 1 0 0 1 1 1 0 Vinculin family Amidase PF01425.21 KXZ51886.1 - 2.5e-67 227.8 1.3 2.2e-54 185.1 1.3 2.0 2 0 0 2 2 2 2 Amidase Fringe PF02434.16 KXZ51887.1 - 1.7e-05 24.4 0.0 5.3e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Fringe-like Lipase_GDSL_2 PF13472.6 KXZ51888.1 - 1.2e-05 25.8 0.1 4.6e-05 23.9 0.1 2.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Kelch_3 PF13415.6 KXZ51889.1 - 1.3e-24 85.9 3.7 8.8e-08 32.2 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KXZ51889.1 - 1.4e-20 73.1 8.5 2.6e-08 33.7 0.0 6.5 4 3 3 7 7 7 4 Galactose oxidase, central domain LRR_8 PF13855.6 KXZ51889.1 - 1.6e-20 72.6 10.5 3.8e-09 36.2 0.4 4.4 1 1 3 4 4 4 4 Leucine rich repeat Kelch_6 PF13964.6 KXZ51889.1 - 5.1e-19 67.8 0.4 0.0008 19.6 0.0 6.8 7 1 1 8 8 8 4 Kelch motif Kelch_2 PF07646.15 KXZ51889.1 - 5.9e-15 54.6 2.5 3.7e-05 23.5 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KXZ51889.1 - 8.7e-15 54.3 0.0 0.00029 20.8 0.0 5.6 5 0 0 5 5 5 3 Kelch motif LRR_4 PF12799.7 KXZ51889.1 - 2e-12 47.1 13.6 0.00022 21.6 1.8 4.8 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) Kelch_1 PF01344.25 KXZ51889.1 - 6.7e-12 44.8 0.1 0.00013 21.5 0.0 5.3 5 0 0 5 5 5 2 Kelch motif LRR_6 PF13516.6 KXZ51889.1 - 7.1e-06 25.7 7.1 0.039 14.0 0.2 5.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 KXZ51889.1 - 0.00073 19.1 6.4 0.0028 17.2 2.3 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 KXZ51889.1 - 0.0027 18.0 4.5 59 4.8 0.0 6.3 7 0 0 7 7 6 0 Leucine Rich Repeat Phage_r1t_holin PF16945.5 KXZ51890.1 - 0.52 10.5 2.9 0.57 10.4 0.2 2.5 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin TrmO PF01980.16 KXZ51893.1 - 9.3e-42 142.0 0.0 1.5e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 tRNA-methyltransferase O CCDC-167 PF15188.6 KXZ51893.1 - 1.2 9.5 4.1 1.9 8.9 4.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4436 PF14494.6 KXZ51894.1 - 4e-17 62.4 0.5 4.9e-17 62.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) FxsA PF04186.13 KXZ51894.1 - 0.052 13.7 1.1 0.052 13.7 1.1 2.4 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein DUF2207 PF09972.9 KXZ51894.1 - 0.12 11.2 0.5 0.15 10.8 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SLC3A2_N PF16028.5 KXZ51894.1 - 0.6 9.7 2.1 21 4.8 0.4 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus BPD_transp_1 PF00528.22 KXZ51894.1 - 2.2 8.0 10.6 8.5 6.1 10.6 1.8 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF4436 PF14494.6 KXZ51895.1 - 1.4e-15 57.3 1.5 1.8e-15 56.9 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF2207 PF09972.9 KXZ51895.1 - 0.1 11.4 0.2 0.1 11.3 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SLC3A2_N PF16028.5 KXZ51895.1 - 0.13 11.8 2.6 5.4 6.6 0.5 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus BPD_transp_1 PF00528.22 KXZ51895.1 - 1.2 8.8 10.4 8.5 6.1 10.4 2.0 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component GST_C_3 PF14497.6 KXZ51896.1 - 2e-12 47.1 0.0 3.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXZ51896.1 - 2.7e-06 27.5 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXZ51896.1 - 0.02 15.3 0.0 0.11 12.8 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ51896.1 - 0.059 13.4 2.0 0.21 11.6 2.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 6PF2K PF01591.18 KXZ51897.1 - 7.5e-69 231.4 0.2 1.2e-68 230.7 0.0 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXZ51897.1 - 2.5e-30 105.6 0.0 9.2e-29 100.5 0.0 2.5 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXZ51897.1 - 2.1e-05 24.7 0.0 4.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ51897.1 - 0.00048 20.4 0.0 0.00099 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KXZ51897.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_18 PF13238.6 KXZ51897.1 - 0.085 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXZ51897.1 - 0.092 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXZ51897.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 KXZ51897.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KXZ51897.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF667 PF05018.13 KXZ51898.1 - 1.2e-25 90.3 0.0 1.5e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DUF2922 PF11148.8 KXZ51898.1 - 0.022 14.5 0.1 0.048 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) WD40 PF00400.32 KXZ51899.1 - 3.8e-15 56.0 0.0 0.005 17.7 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51899.1 - 0.0037 17.5 0.0 8.1 6.8 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KXZ51899.1 - 0.12 10.9 0.3 2.7 6.4 0.1 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 KXZ51899.1 - 0.29 11.7 7.0 18 6.0 0.2 4.6 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.32 KXZ51900.1 - 1.1e-06 29.3 0.0 0.0012 19.6 0.0 4.3 3 1 1 4 4 4 1 WD domain, G-beta repeat UFD1 PF03152.14 KXZ51901.1 - 1.8e-71 239.2 0.0 2.2e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 KXZ51901.1 - 0.028 14.6 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Rubis-subs-bind PF09273.11 KXZ51903.1 - 3.3e-06 27.8 0.1 6.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Bromodomain PF00439.25 KXZ51904.1 - 1.2e-07 31.6 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain cobW PF02492.19 KXZ51905.1 - 4.7e-33 114.2 0.3 7.2e-33 113.6 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ51905.1 - 6.3e-23 80.5 0.3 1.7e-22 79.1 0.1 1.9 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KXZ51905.1 - 0.045 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ELMO_CED12 PF04727.13 KXZ51907.1 - 4.5e-22 79.0 0.0 1.9e-21 77.0 0.0 2.0 2 1 0 2 2 2 1 ELMO/CED-12 family Radial_spoke PF04712.12 KXZ51907.1 - 0.053 12.5 5.4 0.095 11.6 5.4 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Med8 PF10232.9 KXZ51907.1 - 0.16 11.5 4.0 0.31 10.6 4.0 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 PI3K_1B_p101 PF10486.9 KXZ51907.1 - 0.34 8.6 3.0 0.48 8.1 3.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.6 KXZ51907.1 - 0.49 10.1 5.5 1.1 8.9 5.5 1.5 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 KXZ51907.1 - 0.61 9.8 7.5 0.96 9.2 7.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4637 PF15470.6 KXZ51907.1 - 0.81 9.4 12.3 1.7 8.4 12.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pes-10 PF07149.11 KXZ51907.1 - 2.5 7.1 8.0 3.8 6.5 8.0 1.2 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 KXZ51907.1 - 3.4 5.8 6.9 4.7 5.4 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXZ51907.1 - 5.8 5.0 12.1 8 4.5 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KXZ51907.1 - 7.1 4.6 10.5 9.7 4.2 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Neur_chan_memb PF02932.16 KXZ51908.1 - 3.3e-07 30.6 8.4 4.5e-07 30.2 8.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KXZ51908.1 - 0.0024 17.3 1.3 0.0099 15.3 1.3 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain MFS_1 PF07690.16 KXZ51909.1 - 1.1e-34 119.9 46.8 2.3e-26 92.5 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ51909.1 - 3.1e-05 23.0 4.4 3.1e-05 23.0 4.4 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXZ51909.1 - 0.34 9.7 8.4 0.042 12.7 3.8 1.7 2 0 0 2 2 2 0 MFS_1 like family IBR PF01485.21 KXZ51910.1 - 2.3e-14 53.3 22.6 2e-09 37.5 7.1 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KXZ51910.1 - 5.1e-06 26.2 5.3 5.1e-06 26.2 5.3 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ51910.1 - 5.1e-05 23.2 4.3 5.1e-05 23.2 4.3 4.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXZ51910.1 - 9e-05 22.7 5.4 9e-05 22.7 5.4 5.2 3 3 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 KXZ51910.1 - 0.0001 22.1 10.1 0.0001 22.1 10.1 4.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF3439 PF11921.8 KXZ51910.1 - 0.06 13.3 0.5 0.16 11.9 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) COG5 PF10392.9 KXZ51911.1 - 4e-23 82.0 2.5 4e-23 82.0 2.5 3.0 3 1 0 3 3 3 1 Golgi transport complex subunit 5 COG2 PF06148.11 KXZ51911.1 - 0.018 15.1 1.3 0.018 15.1 1.3 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UDG PF03167.19 KXZ51911.1 - 0.064 13.2 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily Trns_repr_metal PF02583.17 KXZ51911.1 - 0.41 11.0 2.5 1.3 9.5 0.3 3.0 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor FMN_red PF03358.15 KXZ51912.1 - 3.6e-07 30.1 0.0 5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase SSF PF00474.17 KXZ51913.1 - 8e-13 48.0 13.0 8e-13 48.0 13.0 2.2 2 0 0 2 2 2 1 Sodium:solute symporter family Pyr_redox_2 PF07992.14 KXZ51914.1 - 4.6e-11 42.5 0.1 2.6e-10 40.0 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXZ51914.1 - 8e-06 26.0 0.0 8e-06 26.0 0.0 4.7 5 0 0 5 5 5 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXZ51914.1 - 3e-05 24.5 0.1 0.002 18.6 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ51914.1 - 4.2e-05 23.0 0.0 0.32 10.2 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXZ51914.1 - 0.00023 20.5 0.3 0.00039 19.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 KXZ51914.1 - 0.0003 19.3 0.0 0.0024 16.3 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 KXZ51914.1 - 0.019 15.4 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KXZ51914.1 - 0.056 12.1 0.3 0.11 11.2 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KXZ51914.1 - 0.083 11.9 2.6 0.13 11.2 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXZ51914.1 - 0.88 8.8 5.4 0.1 11.8 0.4 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 KXZ51915.1 - 1.7e-11 44.0 0.1 7.8e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KXZ51915.1 - 0.28 10.2 0.0 3.1 6.8 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Phage_sheath_1 PF04984.14 KXZ51916.1 - 0.23 11.3 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain Tcf25 PF04910.14 KXZ51917.1 - 3.4e-71 240.1 0.0 4.3e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_7 PF13176.6 KXZ51917.1 - 0.17 12.0 1.0 8.8 6.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 KXZ51918.1 - 4.9e-10 39.2 0.0 3.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KXZ51918.1 - 0.17 10.9 0.0 3.8 6.5 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_3 PF01494.19 KXZ51919.1 - 2.9e-15 56.4 8.0 5.2e-07 29.2 0.0 3.5 4 0 0 4 4 4 3 FAD binding domain NAD_binding_8 PF13450.6 KXZ51919.1 - 7.8e-05 22.8 0.5 0.00021 21.4 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ51919.1 - 0.00023 20.4 0.6 0.00023 20.4 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXZ51919.1 - 0.00042 20.0 2.0 0.00098 18.8 0.6 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ51919.1 - 0.003 16.8 0.2 0.0054 16.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ51919.1 - 0.031 14.8 0.8 0.068 13.7 0.8 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXZ51919.1 - 0.07 12.2 1.1 0.19 10.7 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXZ51919.1 - 1.2 9.1 4.3 0.49 10.4 0.5 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXZ51920.1 - 1.3e-15 57.5 2.7 1.3e-06 27.9 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXZ51920.1 - 1e-05 25.7 0.4 2.6e-05 24.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ51920.1 - 0.00019 20.7 0.6 0.00032 19.9 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXZ51920.1 - 0.00079 19.1 0.2 0.00079 19.1 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ51920.1 - 0.00085 18.6 0.1 0.0014 17.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ51920.1 - 0.006 17.1 1.0 0.013 16.1 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXZ51920.1 - 0.015 14.4 0.6 0.064 12.3 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KXZ51920.1 - 0.073 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KXZ51920.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 KXZ51920.1 - 0.16 11.0 0.0 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 KXZ51920.1 - 0.27 11.2 2.4 0.24 11.4 0.4 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXZ51921.1 - 1.4e-15 57.5 0.4 7.2e-07 28.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXZ51921.1 - 1.8e-06 28.1 0.4 5.9e-06 26.4 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ51921.1 - 6.6e-05 22.6 0.5 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ51921.1 - 0.003 16.9 0.2 0.005 16.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ51921.1 - 0.0032 18.0 0.4 0.0057 17.2 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXZ51921.1 - 0.099 11.7 1.3 0.12 11.4 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXZ51921.1 - 0.14 12.1 2.0 0.15 12.1 0.3 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KXZ51921.1 - 0.18 10.4 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KXZ51921.1 - 0.25 11.2 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Inositol_P PF00459.25 KXZ51922.1 - 6.7e-48 163.6 0.0 8.1e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TFIIA PF03153.13 KXZ51923.1 - 1.9 8.4 20.4 3.1 7.7 20.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 KXZ51923.1 - 2 9.1 19.9 0.12 13.1 12.9 2.2 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 KXZ51923.1 - 5.9 5.0 13.3 7.7 4.6 13.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IFT81_CH PF18383.1 KXZ51924.1 - 8.2e-27 93.9 0.0 3.7e-26 91.8 0.0 2.2 1 0 0 1 1 1 1 Intraflagellar transport 81 calponin homology domain Baculo_PEP_C PF04513.12 KXZ51924.1 - 0.22 11.5 18.1 1.4 8.9 1.2 4.7 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KXZ51924.1 - 3.1 8.3 29.6 0.63 10.5 1.3 6.8 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 KXZ51924.1 - 4.1 7.3 7.2 1.9 8.3 0.5 4.1 3 1 1 4 4 4 0 DASH complex subunit Dam1 Med9 PF07544.13 KXZ51924.1 - 6.8 6.9 40.2 0.026 14.6 6.9 5.4 5 0 0 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Thiolase_N PF00108.23 KXZ51925.1 - 5.1e-79 265.3 4.0 7.9e-79 264.7 4.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXZ51925.1 - 6.5e-47 158.2 0.6 1.3e-46 157.2 0.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KXZ51925.1 - 0.0096 16.1 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal C2 PF00168.30 KXZ51926.1 - 1.2e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF3248 PF11609.8 KXZ51927.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Seipin PF06775.14 KXZ51929.1 - 2.2e-17 63.8 0.0 3.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) H_PPase PF03030.16 KXZ51933.1 - 2.2e-253 842.7 30.8 2.5e-253 842.5 30.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase NDUFA12 PF05071.16 KXZ51934.1 - 3.2e-30 104.8 18.3 1.4e-18 67.5 3.5 2.1 1 1 1 2 2 2 2 NADH ubiquinone oxidoreductase subunit NDUFA12 PGDYG PF14083.6 KXZ51934.1 - 0.021 15.0 4.1 2.1 8.6 0.2 2.5 1 1 1 2 2 2 0 PGDYG protein BACK PF07707.15 KXZ51936.1 - 1.8e-05 24.8 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch TilS PF09179.11 KXZ51936.1 - 0.56 10.7 4.5 0.73 10.4 0.8 2.8 2 0 0 2 2 2 0 TilS substrate binding domain Ank_4 PF13637.6 KXZ51937.1 - 9.6e-06 26.1 0.0 0.57 10.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ51937.1 - 0.011 16.2 0.1 2.8 8.8 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 KXZ51937.1 - 0.076 13.6 0.0 1.1 9.9 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) DUF4129 PF13559.6 KXZ51937.1 - 0.081 13.2 0.3 0.081 13.2 0.3 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4129) Ank_4 PF13637.6 KXZ51938.1 - 1.1e-05 25.8 4.5 1.1 10.0 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51938.1 - 3.7e-05 24.2 0.0 1.4 9.6 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ51938.1 - 4.8e-05 23.4 0.3 4.8 8.1 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeat ATG16 PF08614.11 KXZ51939.1 - 0.016 15.4 9.3 0.024 14.9 9.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Striatin PF08232.12 KXZ51939.1 - 0.023 15.3 3.3 0.035 14.7 3.3 1.2 1 0 0 1 1 1 0 Striatin family Atg14 PF10186.9 KXZ51939.1 - 0.19 10.8 1.1 0.25 10.4 1.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31_Bap29_C PF18035.1 KXZ51939.1 - 0.39 10.7 1.6 3.5 7.7 0.1 2.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4404 PF14357.6 KXZ51939.1 - 0.89 10.2 3.0 0.86 10.3 0.3 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) CENP-Q PF13094.6 KXZ51939.1 - 3.7 7.7 8.5 7 6.8 8.4 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DPBB_1 PF03330.18 KXZ51940.1 - 2e-11 44.0 0.1 3.4e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Lytic transglycolase ERO1 PF04137.15 KXZ51941.1 - 4.5e-115 384.6 0.0 5.5e-115 384.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF1180 PF06679.12 KXZ51941.1 - 0.4 11.1 1.9 0.78 10.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ank_4 PF13637.6 KXZ51943.1 - 2.1e-07 31.3 0.7 1.9 9.2 0.0 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ51943.1 - 0.0019 18.8 0.0 1.7 9.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ51943.1 - 0.015 15.8 0.2 77 4.4 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 KXZ51943.1 - 0.025 14.9 2.1 0.47 10.8 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Peptidase_M16 PF00675.20 KXZ51944.1 - 4.4e-15 55.9 0.1 8.7e-15 55.0 0.0 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXZ51946.1 - 5.4e-31 108.0 0.0 1.1e-30 107.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXZ51946.1 - 1.4e-16 60.8 0.0 2.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SlyX PF04102.12 KXZ51947.1 - 1.9 9.1 10.5 4 8.1 7.5 2.6 2 0 0 2 2 2 0 SlyX Yip1 PF04893.17 KXZ51949.1 - 6.8e-15 55.2 14.0 1.5e-14 54.1 14.0 1.6 1 1 0 1 1 1 1 Yip1 domain CAP_N PF01213.19 KXZ51949.1 - 2.6 7.4 4.6 0.31 10.5 0.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PQ-loop PF04193.14 KXZ51950.1 - 1.5e-18 66.3 0.3 1e-09 38.0 0.3 2.5 2 0 0 2 2 2 2 PQ loop repeat MatE PF01554.18 KXZ51951.1 - 0.03 14.0 0.1 0.03 14.0 0.1 1.6 2 0 0 2 2 2 0 MatE LapA_dom PF06305.11 KXZ51951.1 - 0.82 9.5 6.2 1.4 8.8 6.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4495 PF14906.6 KXZ51953.1 - 0.014 14.5 0.2 0.018 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) GPS2_interact PF15784.5 KXZ51953.1 - 0.019 15.4 5.2 0.03 14.7 5.2 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain YbfN PF13982.6 KXZ51953.1 - 0.024 14.9 1.2 0.036 14.4 0.2 1.8 2 1 0 2 2 2 0 YbfN-like lipoprotein APG6_N PF17675.1 KXZ51953.1 - 0.036 14.6 10.8 0.027 15.0 9.5 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KXZ51953.1 - 0.13 12.5 10.4 0.15 12.3 10.0 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain KxDL PF10241.9 KXZ51953.1 - 0.13 12.6 6.9 0.076 13.3 4.6 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF2746 PF10874.8 KXZ51953.1 - 0.14 12.6 0.7 0.21 12.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) DUF2721 PF11026.8 KXZ51953.1 - 0.16 11.9 0.5 0.23 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) CorA PF01544.18 KXZ51953.1 - 0.21 10.9 4.8 0.26 10.6 4.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TMF_TATA_bd PF12325.8 KXZ51953.1 - 0.24 11.6 10.9 0.19 12.0 7.2 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GvpL_GvpF PF06386.11 KXZ51953.1 - 0.25 11.3 6.1 0.29 11.0 6.1 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TMPIT PF07851.13 KXZ51953.1 - 0.38 10.0 7.9 0.42 9.8 7.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 KXZ51953.1 - 0.54 10.1 8.4 0.61 9.9 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HAUS6_N PF14661.6 KXZ51953.1 - 0.68 9.5 8.0 0.96 9.0 7.9 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spc7 PF08317.11 KXZ51953.1 - 0.93 8.3 14.0 1.1 8.0 14.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Lge1 PF11488.8 KXZ51953.1 - 1.1 9.5 10.2 11 6.2 10.2 2.0 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 TFIIA PF03153.13 KXZ51956.1 - 0.03 14.3 2.7 0.032 14.2 2.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PSI_PSAK PF01241.18 KXZ51959.1 - 2.2e-20 72.4 2.8 3e-20 72.0 2.8 1.2 1 0 0 1 1 1 1 Photosystem I psaG / psaK FAD_binding_3 PF01494.19 KXZ51960.1 - 7.1e-09 35.4 0.1 0.00019 20.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KXZ51960.1 - 0.0082 15.2 0.0 1.2 8.1 0.0 2.7 3 0 0 3 3 3 2 Squalene epoxidase Ald_Xan_dh_C2 PF02738.18 KXZ51961.1 - 9.9e-76 255.3 2.3 2.2e-33 115.6 0.5 3.5 4 0 0 4 4 4 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 KXZ51961.1 - 1.1e-15 58.0 0.0 5.6e-15 55.6 0.0 2.3 1 1 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 KXZ51961.1 - 1.7e-15 57.1 0.5 5.9e-15 55.4 0.5 1.9 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KXZ51961.1 - 0.0038 17.4 11.8 0.36 11.0 0.4 4.6 3 0 0 3 3 3 2 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C2 PF02738.18 KXZ51962.1 - 1.1e-27 96.8 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Rieske PF00355.26 KXZ51963.1 - 1.9e-21 75.8 0.2 3.8e-21 74.8 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ51963.1 - 1e-13 51.2 0.0 3.2e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Pheophorbide a oxygenase Rieske_2 PF13806.6 KXZ51963.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Optomotor-blind PF11078.8 KXZ51963.1 - 2.9 8.5 8.3 0.51 10.9 3.3 2.4 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region FAD_binding_3 PF01494.19 KXZ51964.1 - 7.8e-14 51.7 1.6 0.00051 19.4 0.4 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 KXZ51964.1 - 1e-07 31.9 0.0 1.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXZ51964.1 - 6.3e-05 23.1 0.2 0.00016 21.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ51964.1 - 0.00026 20.3 0.2 0.00037 19.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ51964.1 - 0.00049 19.3 2.4 0.00066 18.9 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXZ51964.1 - 0.00058 19.2 0.2 0.00087 18.6 0.2 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXZ51964.1 - 0.00059 18.6 0.4 0.00081 18.2 0.4 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KXZ51964.1 - 0.018 14.4 0.7 0.025 13.9 0.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXZ51964.1 - 0.018 13.9 0.1 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KXZ51964.1 - 0.02 14.9 0.2 0.054 13.5 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXZ51964.1 - 0.025 13.9 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXZ51964.1 - 0.029 13.5 0.3 0.041 13.0 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXZ51964.1 - 0.13 11.3 0.3 0.2 10.6 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Rieske PF00355.26 KXZ51965.1 - 9.2e-21 73.6 0.2 1.7e-20 72.7 0.2 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ51965.1 - 2e-14 53.5 0.0 5.1e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Pheophorbide a oxygenase Rieske_2 PF13806.6 KXZ51965.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF983 PF06170.12 KXZ51965.1 - 0.28 11.6 1.5 0.48 10.9 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Proteasome PF00227.26 KXZ51966.1 - 5.3e-59 198.9 0.0 6.4e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXZ51966.1 - 1e-13 50.7 0.0 1.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature G6PD_C PF02781.16 KXZ51967.1 - 2.1e-78 263.5 0.0 1.6e-64 217.9 0.0 2.1 2 0 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXZ51967.1 - 5.5e-52 176.9 0.0 4.7e-51 173.9 0.0 2.0 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain La PF05383.17 KXZ51968.1 - 6.4e-22 77.4 0.0 1.3e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXZ51968.1 - 7.4e-10 38.5 0.1 3.8e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXZ51968.1 - 1.1e-06 28.6 0.0 1.5e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif OxoDH_E1alpha_N PF12573.8 KXZ51968.1 - 0.057 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Dynamin_M PF01031.20 KXZ51969.1 - 2.2e-75 253.5 0.0 3e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXZ51969.1 - 2.1e-50 171.1 0.0 2.9e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXZ51969.1 - 2.3e-25 88.5 0.1 4.5e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXZ51969.1 - 4.9e-05 23.4 0.0 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KXZ51969.1 - 0.081 12.6 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 KXZ51969.1 - 0.23 11.8 2.0 11 6.4 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain GTP_EFTU_D3 PF03143.17 KXZ51970.1 - 8.6e-13 48.6 0.0 9.1e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain RVT_2 PF07727.14 KXZ51971.1 - 1.6e-12 47.6 0.0 1.8e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 KXZ51972.1 - 0.0016 18.4 0.5 0.66 9.9 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family PaO PF08417.12 KXZ51973.1 - 2e-13 50.3 0.0 3.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske PF00355.26 KXZ51974.1 - 1.1e-21 76.6 0.1 1.6e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXZ51974.1 - 8.5e-05 22.4 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Optomotor-blind PF11078.8 KXZ51974.1 - 0.0034 17.9 1.9 0.0065 17.0 1.9 1.5 1 0 0 1 1 1 1 Optomotor-blind protein N-terminal region CAF1C_H4-bd PF12265.8 KXZ51975.1 - 1.5e-15 57.2 0.0 4.1e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXZ51975.1 - 5.5e-15 55.5 9.9 3.9e-05 24.3 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51975.1 - 0.00071 19.8 0.2 3.2 8.1 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CENP-B_dimeris PF09026.10 KXZ51975.1 - 0.021 15.2 6.3 0.044 14.2 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.13 KXZ51975.1 - 0.038 14.1 1.6 0.07 13.2 1.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 KXZ51975.1 - 0.11 12.2 4.5 0.23 11.2 4.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KXZ51975.1 - 0.29 10.4 7.1 0.43 9.9 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KXZ51975.1 - 0.44 10.6 1.3 0.78 9.8 1.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FCP1_C PF09309.10 KXZ51975.1 - 1.4 8.8 6.7 2.3 8.1 6.7 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DNA_pol_phi PF04931.13 KXZ51975.1 - 3 5.8 7.3 4.4 5.3 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CLZ PF16526.5 KXZ51976.1 - 0.87 10.0 0.0 0.87 10.0 0.0 3.2 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EF-hand_7 PF13499.6 KXZ51977.1 - 0.059 13.8 0.0 0.21 12.1 0.0 2.0 2 1 0 2 2 2 0 EF-hand domain pair HrpB7 PF09486.10 KXZ51978.1 - 0.049 14.0 12.9 0.043 14.2 11.9 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) OmpH PF03938.14 KXZ51978.1 - 2.5 8.4 10.6 3.1 8.1 10.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tcp10_C PF07202.13 KXZ51979.1 - 4.8e-13 49.4 0.0 6.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 10 C-terminus MORN_2 PF07661.13 KXZ51979.1 - 0.098 12.9 0.1 21 5.8 0.0 2.7 2 0 0 2 2 2 0 MORN repeat variant Myb_DNA-binding PF00249.31 KXZ51980.1 - 1.4e-12 47.5 1.3 2.3e-12 46.9 1.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ51980.1 - 0.0013 18.9 0.2 0.0024 18.1 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXZ51980.1 - 0.0082 16.0 0.5 0.016 15.1 0.5 1.3 1 0 0 1 1 1 1 Myb DNA-binding like NFACT-R_1 PF05670.13 KXZ51981.1 - 2.6e-27 95.6 0.2 9.2e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 NFACT protein RNA binding domain DUF1318 PF07027.12 KXZ51981.1 - 0.0023 18.3 1.8 0.0049 17.3 1.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1318) Macoilin PF09726.9 KXZ51981.1 - 0.49 8.9 13.5 0.61 8.6 13.5 1.1 1 0 0 1 1 1 0 Macoilin family HAUS6_N PF14661.6 KXZ51981.1 - 0.72 9.4 8.6 0.93 9.0 8.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2457 PF10446.9 KXZ51984.1 - 6.1 5.9 6.7 9.5 5.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRM_1 PF00076.22 KXZ51985.1 - 7.2e-31 105.8 0.1 3.4e-18 65.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXZ51985.1 - 0.00023 21.1 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXZ51985.1 - 0.35 10.9 0.0 0.35 10.9 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif Peptidase_C26 PF07722.13 KXZ51986.1 - 1e-17 64.6 0.0 2e-17 63.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KXZ51986.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I MtN3_slv PF03083.16 KXZ51987.1 - 0.00027 20.9 0.0 0.00033 20.6 0.0 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange RNA_pol PF00940.19 KXZ51987.1 - 0.18 10.6 0.0 0.19 10.6 0.0 1.0 1 0 0 1 1 1 0 DNA-dependent RNA polymerase MtN3_slv PF03083.16 KXZ51988.1 - 8.9e-31 105.8 5.3 1.5e-18 66.6 1.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange ABC2_membrane PF01061.24 KXZ51988.1 - 0.037 13.4 8.2 0.029 13.8 6.8 1.6 1 1 0 1 1 1 0 ABC-2 type transporter Bax1-I PF01027.20 KXZ51988.1 - 0.16 11.8 12.1 0.036 13.9 8.3 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.11 KXZ51988.1 - 0.46 10.4 13.0 0.56 10.1 13.0 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling Beach PF02138.18 KXZ51989.1 - 5e-102 341.0 0.0 1.1e-101 339.9 0.0 1.5 1 1 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 KXZ51989.1 - 8.1e-05 23.3 4.2 0.00099 19.9 0.3 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat PH_BEACH PF14844.6 KXZ51989.1 - 0.003 17.6 0.0 0.26 11.4 0.0 3.2 3 1 0 3 3 3 1 PH domain associated with Beige/BEACH DivIC PF04977.15 KXZ51990.1 - 0.0014 18.3 0.0 0.0077 16.0 0.0 1.9 2 0 0 2 2 2 1 Septum formation initiator TolA_bind_tri PF16331.5 KXZ51990.1 - 0.0066 16.5 0.6 0.011 15.8 0.6 1.3 1 0 0 1 1 1 1 TolA binding protein trimerisation HALZ PF02183.18 KXZ51990.1 - 0.021 15.0 0.2 0.043 14.0 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mto2_bdg PF12808.7 KXZ51990.1 - 0.022 15.0 2.1 0.041 14.2 2.1 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.15 KXZ51990.1 - 0.027 14.5 2.7 0.059 13.5 1.6 1.9 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 KXZ51990.1 - 0.04 14.0 1.0 0.072 13.2 0.3 1.7 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 KXZ51990.1 - 0.11 12.8 0.5 0.24 11.7 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 KXZ51991.1 - 0.0025 17.6 0.1 0.018 14.8 0.1 2.3 3 0 0 3 3 3 1 Septum formation initiator DUF1192 PF06698.11 KXZ51991.1 - 0.024 14.7 1.7 0.073 13.1 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) bZIP_1 PF00170.21 KXZ51991.1 - 0.028 14.5 0.6 0.051 13.7 0.2 1.6 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 KXZ51991.1 - 0.052 13.6 1.3 0.13 12.4 0.5 1.8 2 0 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.18 KXZ51991.1 - 0.092 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper AAA PF00004.29 KXZ51992.1 - 1.1e-43 148.8 0.0 3.5e-13 50.1 0.0 5.1 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KXZ51992.1 - 1.4e-35 122.7 0.0 5.5e-35 120.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXZ51992.1 - 2.7e-26 92.9 17.0 1e-21 78.0 0.0 6.4 5 1 0 5 5 5 1 AAA domain AAA_19 PF13245.6 KXZ51992.1 - 1.7e-17 64.1 1.5 5.2e-10 39.8 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA_lid_6 PF17866.1 KXZ51992.1 - 1.2e-15 57.4 18.0 8e-08 32.4 3.3 4.1 3 0 0 3 3 3 2 AAA lid domain AAA_5 PF07728.14 KXZ51992.1 - 1.6e-14 54.1 1.3 0.037 14.0 0.0 6.1 5 0 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXZ51992.1 - 1.1e-13 51.4 20.6 1.9e-05 24.5 0.0 7.3 8 0 0 8 8 6 4 AAA domain AAA_22 PF13401.6 KXZ51992.1 - 2.4e-13 50.5 7.1 0.056 13.7 0.1 7.7 5 3 0 5 5 4 3 AAA domain RuvB_N PF05496.12 KXZ51992.1 - 8.7e-11 41.8 0.6 0.00065 19.5 0.0 5.2 5 1 0 5 5 5 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXZ51992.1 - 1.4e-09 37.7 0.8 0.39 10.1 0.0 6.0 4 2 2 6 6 6 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXZ51992.1 - 9.8e-08 32.6 2.8 0.79 10.3 0.1 5.1 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 KXZ51992.1 - 1.1e-07 32.2 0.0 0.62 10.5 0.0 4.5 4 0 0 4 4 4 2 RNA helicase Sigma54_activat PF00158.26 KXZ51992.1 - 9.6e-07 28.6 2.3 3.2 7.4 0.0 6.2 5 2 0 5 5 4 1 Sigma-54 interaction domain ResIII PF04851.15 KXZ51992.1 - 1e-05 25.6 3.4 0.0041 17.1 0.0 5.0 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit AAA_2 PF07724.14 KXZ51992.1 - 1.1e-05 25.6 0.0 0.042 14.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KXZ51992.1 - 4.7e-05 22.9 0.1 0.07 12.6 0.0 4.1 4 0 0 4 4 4 1 PhoH-like protein Viral_helicase1 PF01443.18 KXZ51992.1 - 8e-05 22.5 0.7 3.9 7.2 0.0 4.7 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KXZ51992.1 - 0.00011 21.8 0.4 4.2 6.8 0.0 4.1 4 0 0 4 4 4 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXZ51992.1 - 0.0002 21.1 0.4 8.3 6.1 0.0 4.5 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 KXZ51992.1 - 0.00037 20.1 2.6 1.1 8.8 0.0 5.6 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 KXZ51992.1 - 0.0005 19.8 0.2 15 5.3 0.0 4.3 4 0 0 4 4 4 0 AAA domain Torsin PF06309.11 KXZ51992.1 - 0.00069 19.7 0.0 13 5.9 0.0 4.3 4 0 0 4 4 4 0 Torsin Sigma54_activ_2 PF14532.6 KXZ51992.1 - 0.00073 19.7 0.1 3.3 7.8 0.0 4.3 4 1 0 4 4 4 1 Sigma-54 interaction domain NTPase_1 PF03266.15 KXZ51992.1 - 0.00081 19.3 1.7 1.7 8.5 0.0 4.3 4 0 0 4 4 4 1 NTPase UvrD-helicase PF00580.21 KXZ51992.1 - 0.00085 18.9 8.9 0.038 13.5 0.0 5.0 6 0 0 6 6 6 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KXZ51992.1 - 0.0015 17.9 0.0 0.0015 17.9 0.0 6.4 7 2 0 8 8 7 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KXZ51992.1 - 0.0049 16.2 0.9 6.4 6.0 0.0 4.1 4 0 0 4 4 4 0 KaiC DEAD PF00270.29 KXZ51992.1 - 0.012 15.3 0.0 0.33 10.7 0.0 3.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 KXZ51992.1 - 0.15 12.5 37.6 0.16 12.4 0.0 8.6 8 2 0 8 8 5 0 AAA ATPase domain AAA_33 PF13671.6 KXZ51992.1 - 0.19 11.9 0.1 0.19 11.9 0.1 6.3 7 0 0 7 7 5 0 AAA domain NACHT PF05729.12 KXZ51992.1 - 1 9.3 4.0 98 2.8 0.1 4.4 4 0 0 4 4 4 0 NACHT domain AAA_12 PF13087.6 KXZ51993.1 - 5.7e-34 117.5 0.0 8.5e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ51993.1 - 3.4e-22 79.5 0.0 3.4e-22 79.5 0.0 3.5 2 2 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KXZ51993.1 - 8.7e-10 39.1 0.0 8.8e-09 35.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ51993.1 - 1.9e-08 34.2 2.0 1.2e-05 25.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 KXZ51993.1 - 2.5e-06 27.0 4.2 0.00066 19.0 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KXZ51993.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KXZ51993.1 - 0.0015 18.1 0.0 0.027 14.0 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KXZ51993.1 - 0.02 14.4 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KXZ51993.1 - 0.032 14.5 0.0 0.19 12.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXZ51993.1 - 0.095 12.4 0.0 0.68 9.6 0.0 2.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KXZ51993.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 KXZ51993.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.4 4 1 0 4 4 3 0 AAA ATPase domain AAA PF00004.29 KXZ51993.1 - 0.13 12.7 0.4 1.1 9.7 0.2 2.7 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ51993.1 - 0.13 12.2 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4140 PF13600.6 KXZ51994.1 - 0.013 15.9 2.4 4.9 7.7 1.5 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 KXZ51994.1 - 0.16 12.3 6.0 0.28 11.5 6.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lebercilin PF15619.6 KXZ51994.1 - 0.23 11.1 8.9 0.39 10.4 6.0 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 KXZ51994.1 - 6.6 6.6 8.1 4.9 7.0 5.6 2.0 2 0 0 2 2 2 0 Septum formation initiator Rpn3_C PF08375.11 KXZ51995.1 - 1.7e-27 95.6 2.7 3.8e-27 94.5 2.7 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KXZ51995.1 - 3.6e-19 69.2 0.0 9e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KXZ51995.1 - 0.0093 16.0 0.1 0.0093 16.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 KXZ51995.1 - 0.059 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_1 PF00515.28 KXZ51995.1 - 0.092 12.6 0.1 0.092 12.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 KXZ51996.1 - 1.2e-31 110.1 0.0 2.6e-31 109.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXZ51996.1 - 2.1e-08 34.1 0.1 7.4e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 KXZ51996.1 - 0.0023 17.8 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 KXZ51998.1 - 9.3e-24 83.3 4.7 1.4e-05 25.7 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ51998.1 - 0.00047 20.4 0.0 0.7 10.2 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXZ51998.1 - 0.2 10.3 0.1 0.47 9.0 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CENP-T_C PF15511.6 KXZ52000.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ52000.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ52000.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ52000.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ52000.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ52000.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ52000.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated U-box PF04564.15 KXZ52001.1 - 3.5e-10 39.9 0.0 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 2 U-box domain zf-Nse PF11789.8 KXZ52001.1 - 0.045 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Beta_helix PF13229.6 KXZ52003.1 - 0.0021 17.9 0.1 0.031 14.1 0.0 2.6 1 1 1 2 2 2 1 Right handed beta helix region Histone PF00125.24 KXZ52004.1 - 2.5e-21 76.4 7.9 3.8e-21 75.8 7.9 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52004.1 - 2.8e-05 24.3 0.1 8.3e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ52004.1 - 0.0019 18.6 0.0 0.0031 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ52004.1 - 0.015 15.4 4.6 0.027 14.5 4.6 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ52004.1 - 0.028 14.1 0.5 1.3 8.6 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ52004.1 - 1.3 9.6 8.7 3.5 8.2 8.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) U-box PF04564.15 KXZ52005.1 - 1.3e-18 66.9 0.0 2.4e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 U-box domain zf-Nse PF11789.8 KXZ52005.1 - 0.013 15.3 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Beta_helix PF13229.6 KXZ52005.1 - 0.029 14.2 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 Right handed beta helix region Pex14_N PF04695.13 KXZ52005.1 - 0.049 14.3 3.7 0.14 12.9 3.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CENP-T_C PF15511.6 KXZ52006.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ52006.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ52006.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ52006.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ52006.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ52006.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ52006.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ52007.1 - 1.2e-49 168.0 4.8 4.2e-35 121.0 0.8 2.0 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXZ52007.1 - 2.7e-05 24.2 0.8 0.00052 20.1 0.1 2.0 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ52007.1 - 5e-05 23.6 0.1 0.00022 21.5 0.0 1.8 2 0 0 2 2 2 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXZ52007.1 - 0.00029 21.0 0.2 0.0087 16.3 0.1 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF746 PF05344.11 KXZ52007.1 - 0.00099 18.9 2.1 1.1 9.2 0.1 2.7 3 0 0 3 3 3 2 Domain of Unknown Function (DUF746) DUF4840 PF16128.5 KXZ52007.1 - 0.0034 17.4 0.0 1.5 8.9 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4840) TFIID-31kDa PF02291.15 KXZ52007.1 - 0.0053 16.8 0.1 0.01 15.9 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit WASH-7_mid PF14744.6 KXZ52007.1 - 0.0086 15.2 0.4 0.064 12.3 0.2 1.8 1 1 1 2 2 2 2 WASH complex subunit 7 DUF3574 PF12098.8 KXZ52007.1 - 0.011 15.5 0.2 5.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) DZF PF07528.14 KXZ52007.1 - 0.018 14.7 0.1 4.6 6.8 0.0 2.0 1 1 1 2 2 2 0 DZF domain Casein PF00363.18 KXZ52007.1 - 0.03 14.7 0.3 6.3 7.2 0.0 2.1 1 1 1 2 2 2 0 Casein DUF2100 PF09873.9 KXZ52007.1 - 0.038 13.9 0.2 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2100) DUF1823 PF08853.11 KXZ52007.1 - 0.12 12.6 0.1 4.8 7.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1823) Ebp2 PF05890.12 KXZ52007.1 - 0.28 10.7 2.6 4.2 6.8 2.5 1.9 1 1 1 2 2 2 0 Eukaryotic rRNA processing protein EBP2 Pkinase_Tyr PF07714.17 KXZ52008.1 - 1.7e-27 96.4 0.0 2.6e-22 79.3 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ52008.1 - 1.4e-26 93.5 0.0 1.8e-22 80.0 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ52008.1 - 0.00083 18.8 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ52008.1 - 0.053 12.3 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 KXZ52009.1 - 2.7e-06 27.1 0.0 0.017 14.9 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.19 KXZ52009.1 - 1 10.0 18.8 1.9 9.1 18.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SET PF00856.28 KXZ52010.1 - 3e-05 24.5 0.1 0.0029 18.0 0.1 2.8 1 1 0 1 1 1 1 SET domain Methyltransf_PK PF05891.12 KXZ52011.1 - 2.8e-22 79.3 0.0 3.2e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KXZ52011.1 - 0.075 13.7 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 KXZ52012.1 - 4.9e-33 114.5 0.0 6.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase T6SS-SciN PF12790.7 KXZ52012.1 - 0.033 13.9 0.4 0.077 12.7 0.2 1.6 2 0 0 2 2 2 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 CAP PF00188.26 KXZ52013.1 - 8.2e-17 62.2 0.2 1.1e-16 61.8 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FPP PF05911.11 KXZ52015.1 - 0.00019 19.8 0.5 0.00019 19.8 0.5 2.3 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 KXZ52015.1 - 3.4 7.7 40.8 1.1 9.3 3.5 4.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC144C PF14915.6 KXZ52015.1 - 6.8 5.7 39.5 33 3.5 12.5 2.4 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region AAA_13 PF13166.6 KXZ52015.1 - 7.6 5.0 28.2 3.9 6.0 0.1 2.6 1 1 0 2 2 2 0 AAA domain Linker_histone PF00538.19 KXZ52016.1 - 7e-20 71.2 0.6 2.1e-19 69.6 0.6 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family Tn7_Tnp_TnsA_N PF08722.11 KXZ52016.1 - 0.058 13.6 0.0 0.058 13.6 0.0 2.5 1 1 1 2 2 2 0 TnsA endonuclease N terminal CENP-T_C PF15511.6 KXZ52017.1 - 8e-09 35.6 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Linker_histone PF00538.19 KXZ52017.1 - 0.0001 22.6 0.3 0.00058 20.2 0.1 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family CENP-S PF15630.6 KXZ52017.1 - 0.00037 20.8 0.1 0.00061 20.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ52017.1 - 0.00052 20.1 0.1 0.0008 19.5 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ52017.1 - 0.0034 17.6 0.0 0.0058 16.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ52017.1 - 0.0058 17.0 1.4 0.0081 16.5 1.4 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ52017.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ52017.1 - 0.051 13.6 0.1 0.087 12.8 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ52018.1 - 2e-21 76.7 8.4 3.1e-21 76.1 8.4 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52018.1 - 2.4e-05 24.5 0.1 6e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ52018.1 - 0.0018 18.7 0.0 0.0025 18.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ52018.1 - 0.0096 16.0 5.0 0.016 15.2 5.0 1.5 1 1 0 1 1 1 1 YscO-like protein RP-C PF03428.13 KXZ52018.1 - 0.02 14.5 0.6 0.33 10.6 0.2 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ52018.1 - 1.1 9.8 8.9 2.6 8.6 8.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone_H2A_C PF16211.5 KXZ52019.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ52019.1 - 1.6e-16 60.8 0.0 2.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52019.1 - 5.7e-05 23.3 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ank_2 PF12796.7 KXZ52020.1 - 5.6e-08 33.3 0.2 7.4e-08 32.9 0.2 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ52020.1 - 2.2e-06 27.8 1.2 0.0027 18.1 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXZ52020.1 - 5e-06 26.9 0.0 7.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ52020.1 - 0.0005 20.3 0.1 0.00071 19.8 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ52020.1 - 0.021 15.3 0.1 5.7 7.8 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeat Calponin PF00402.18 KXZ52020.1 - 0.064 12.9 5.9 5.8 6.6 0.1 3.5 4 0 0 4 4 4 0 Calponin family repeat Histone_H2A_C PF16211.5 KXZ52022.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ52022.1 - 1.6e-16 60.8 0.0 2.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52022.1 - 5.7e-05 23.3 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ52023.1 - 3.5e-22 79.2 4.6 5e-22 78.7 4.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52023.1 - 2.9e-05 24.3 0.1 8.3e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ52023.1 - 0.0019 18.6 0.0 0.0031 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ52023.1 - 0.0036 17.3 3.5 0.0051 16.8 3.5 1.3 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 KXZ52023.1 - 0.023 14.4 0.2 1.2 8.7 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ52023.1 - 1.2 9.7 7.9 3.4 8.2 7.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone PF00125.24 KXZ52025.1 - 3.5e-22 79.2 4.6 5e-22 78.7 4.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52025.1 - 2.9e-05 24.3 0.1 8.3e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ52025.1 - 0.0019 18.6 0.0 0.0031 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ52025.1 - 0.0036 17.3 3.5 0.0051 16.8 3.5 1.3 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 KXZ52025.1 - 0.023 14.4 0.2 1.2 8.7 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ52025.1 - 1.2 9.7 7.9 3.4 8.2 7.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone_H2A_C PF16211.5 KXZ52026.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ52026.1 - 1.6e-16 60.8 0.0 2.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52026.1 - 5.7e-05 23.3 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CIA30 PF08547.12 KXZ52027.1 - 1.3e-15 57.8 0.0 2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.6 KXZ52027.1 - 2.7e-05 24.1 1.1 5.1e-05 23.2 1.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXZ52027.1 - 0.00035 20.2 0.3 0.00059 19.5 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXZ52027.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KXZ52027.1 - 0.023 14.8 0.3 0.055 13.6 0.3 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KXZ52027.1 - 0.067 12.6 0.3 0.14 11.6 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KXZ52027.1 - 0.082 12.1 0.4 0.28 10.3 0.4 1.8 2 0 0 2 2 2 0 Male sterility protein CAP_N PF01213.19 KXZ52027.1 - 0.083 12.4 0.3 0.083 12.4 0.3 2.2 2 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal 3Beta_HSD PF01073.19 KXZ52027.1 - 0.16 11.0 0.2 0.27 10.2 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_2 PF07992.14 KXZ52028.1 - 2e-55 188.1 0.2 3e-55 187.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ52028.1 - 5.9e-16 58.8 1.8 3.8e-12 46.6 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXZ52028.1 - 4.2e-11 43.1 0.0 9.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Rhodanese PF00581.20 KXZ52028.1 - 4.8e-10 39.9 0.0 1.8e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain NAD_binding_8 PF13450.6 KXZ52028.1 - 3.2e-06 27.3 2.5 0.00038 20.6 0.1 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXZ52028.1 - 0.00018 21.5 1.4 11 6.0 0.0 4.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXZ52028.1 - 0.0022 17.3 0.2 4.8 6.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ52028.1 - 0.031 13.8 6.3 4.8 6.7 0.2 3.8 4 0 0 4 4 4 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXZ52028.1 - 0.068 12.3 0.3 8.7 5.4 0.0 2.6 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AAA_PrkA PF08298.11 KXZ52028.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain TRF PF08558.10 KXZ52029.1 - 0.088 12.4 0.3 0.17 11.4 0.2 1.5 1 1 0 1 1 1 0 Telomere repeat binding factor (TRF) Hint PF01079.20 KXZ52030.1 - 4.5e-25 88.4 0.0 6.5e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.11 KXZ52030.1 - 0.038 14.2 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain Intein_splicing PF14890.6 KXZ52030.1 - 0.11 12.4 0.0 0.54 10.2 0.0 1.9 1 1 0 1 1 1 0 Intein splicing domain EF-hand_5 PF13202.6 KXZ52031.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ52031.1 - 0.0045 16.4 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ52031.1 - 0.0046 16.8 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain TrbC PF04956.13 KXZ52031.1 - 0.039 14.2 1.7 0.053 13.7 1.7 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family Sulf_transp PF04143.14 KXZ52032.1 - 1.8e-12 47.4 50.0 6.1e-09 35.9 21.3 3.2 1 1 2 3 3 3 2 Sulphur transport Metallophos PF00149.28 KXZ52033.1 - 2.9e-09 37.7 0.0 1.4e-06 29.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ52033.1 - 0.00026 21.2 0.0 0.053 13.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain IU_nuc_hydro PF01156.19 KXZ52034.1 - 6.7e-79 265.6 0.1 8.3e-79 265.3 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.25 KXZ52035.1 - 2.5e-67 227.0 0.0 3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52035.1 - 1e-33 116.7 0.0 1.4e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXZ52035.1 - 4.7e-08 32.4 0.1 3.6e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXZ52035.1 - 1.7e-05 24.3 0.2 2.5e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ52035.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ52035.1 - 0.017 14.4 0.1 0.38 10.0 0.0 2.1 1 1 1 2 2 2 0 Kinase-like ABC1 PF03109.16 KXZ52035.1 - 0.13 12.5 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 ABC1 family Pkinase PF00069.25 KXZ52036.1 - 3.8e-66 223.1 0.0 4.6e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52036.1 - 6.9e-32 110.8 0.0 9.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ52036.1 - 3.3e-06 26.6 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ52036.1 - 0.00013 22.0 0.2 0.00051 20.0 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ52036.1 - 0.00015 20.8 0.0 0.00068 18.7 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXZ52036.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ASH PF15780.5 KXZ52037.1 - 4.2e-27 94.2 0.2 2.4e-06 27.7 0.0 6.1 5 1 0 5 5 5 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 KXZ52037.1 - 5.4e-05 23.1 0.0 0.071 13.2 0.0 3.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 KXZ52037.1 - 0.00053 19.8 0.0 0.37 10.6 0.0 4.1 4 0 0 4 4 4 1 MSP (Major sperm protein) domain PapD-like PF14874.6 KXZ52037.1 - 0.007 16.5 0.5 17 5.6 0.0 4.0 5 0 0 5 5 5 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 KXZ52037.1 - 0.049 13.9 0.0 15 5.9 0.0 3.7 4 0 0 4 4 4 0 Transmembrane protein 131-like MaoC_dehydratas PF01575.19 KXZ52037.1 - 0.067 12.8 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 MaoC like domain Hydrolase_6 PF13344.6 KXZ52039.1 - 2.3e-29 101.5 0.0 3.4e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ52039.1 - 3.7e-11 42.9 0.0 7.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXZ52039.1 - 5.2e-05 23.6 0.0 0.002 18.4 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KXZ52039.1 - 0.0039 16.8 0.0 0.084 12.5 0.0 2.5 3 0 0 3 3 3 1 Mitochondrial PGP phosphatase HAD_2 PF13419.6 KXZ52039.1 - 0.063 13.4 0.0 1.7 8.7 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LRR_6 PF13516.6 KXZ52040.1 - 3.9e-23 79.5 26.5 3.2e-05 23.6 0.2 10.3 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 KXZ52040.1 - 2.1e-07 31.1 0.1 0.39 11.2 0.2 6.0 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ52040.1 - 1.4e-05 24.9 0.1 16 6.5 0.2 6.5 5 1 0 5 5 5 1 Leucine Rich Repeat XK-related PF09815.9 KXZ52040.1 - 0.00023 20.3 8.3 0.0011 18.2 8.3 1.8 1 1 0 1 1 1 1 XK-related protein LRR_8 PF13855.6 KXZ52040.1 - 3 7.7 6.4 6.2 6.7 0.0 4.7 7 0 0 7 7 7 0 Leucine rich repeat Peptidase_M20 PF01546.28 KXZ52045.1 - 1.9e-20 73.4 0.0 3.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXZ52045.1 - 6e-15 55.1 0.0 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXZ52045.1 - 0.00032 20.5 0.0 0.00073 19.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 Ribosomal_60s PF00428.19 KXZ52046.1 - 0.00047 20.7 12.6 0.00047 20.7 12.6 4.7 4 1 0 4 4 4 1 60s Acidic ribosomal protein BSP_II PF05432.11 KXZ52046.1 - 0.05 13.3 22.1 0.071 12.8 22.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myb_DNA-bind_4 PF13837.6 KXZ52046.1 - 0.068 13.6 0.3 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Mpp10 PF04006.12 KXZ52046.1 - 0.42 9.0 11.6 0.52 8.7 11.6 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 KXZ52046.1 - 1.3 8.4 11.4 1.9 7.8 11.4 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXZ52046.1 - 6.1 4.9 14.3 7.6 4.6 14.3 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 KXZ52046.1 - 9.7 5.9 7.6 13 5.5 7.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoU_methylase PF00588.19 KXZ52047.1 - 5e-23 81.8 0.1 2.9e-22 79.4 0.1 2.0 1 1 0 1 1 1 1 SpoU rRNA Methylase family Histone PF00125.24 KXZ52048.1 - 6.4e-48 162.4 0.2 7.4e-48 162.2 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ52048.1 - 9.9e-05 22.6 0.0 0.00014 22.2 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ52048.1 - 0.00031 20.8 0.1 0.0004 20.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ52048.1 - 0.0038 17.5 0.1 0.0053 17.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ52048.1 - 0.0075 16.3 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KXZ52049.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ52049.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ52049.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ52049.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ52049.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ52049.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ52049.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ52050.1 - 2.5e-21 76.4 7.9 3.8e-21 75.8 7.9 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52050.1 - 2.8e-05 24.3 0.1 8.3e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ52050.1 - 0.0019 18.6 0.0 0.0031 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ52050.1 - 0.015 15.4 4.6 0.027 14.5 4.6 1.5 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ52050.1 - 0.028 14.1 0.5 1.3 8.6 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ52050.1 - 1.3 9.6 8.7 3.5 8.2 8.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone_H2A_C PF16211.5 KXZ52051.1 - 3e-19 68.4 2.2 5.5e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ52051.1 - 1.6e-16 60.8 0.0 2.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ52051.1 - 5.7e-05 23.3 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IBR PF01485.21 KXZ52052.1 - 9.9e-16 57.7 17.1 3.9e-08 33.4 1.4 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-ACC PF17848.1 KXZ52052.1 - 0.14 12.2 2.4 0.32 11.1 0.2 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Macoilin PF09726.9 KXZ52052.1 - 2.6 6.5 4.2 3.9 5.9 4.2 1.1 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 KXZ52052.1 - 7.5 5.8 10.6 11 5.2 10.6 1.2 1 0 0 1 1 1 0 BUD22 MtN3_slv PF03083.16 KXZ52053.1 - 8.1e-35 118.7 0.9 2e-19 69.4 0.2 2.1 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange EF-hand_8 PF13833.6 KXZ52055.1 - 1.4e-07 31.2 0.0 4.3e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KXZ52055.1 - 0.00013 22.3 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ52055.1 - 0.00018 20.8 0.0 0.0004 19.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ52055.1 - 0.01 15.3 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ52055.1 - 0.15 12.1 0.0 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Uso1_p115_head PF04869.14 KXZ52056.1 - 3e-14 52.9 0.0 8.6e-12 44.8 0.0 3.1 2 1 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KXZ52057.1 - 4.1e-10 40.1 29.2 4.9e-09 36.6 20.2 3.3 2 1 1 3 3 3 2 Uso1 / p115 like vesicle tethering protein, C terminal region Cep57_CLD_2 PF14197.6 KXZ52057.1 - 0.038 14.1 3.9 0.59 10.3 0.5 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 SlyX PF04102.12 KXZ52057.1 - 1.4 9.6 0.0 1.4 9.6 0.0 4.4 4 1 0 4 4 4 0 SlyX RR_TM4-6 PF06459.12 KXZ52057.1 - 2.3 8.0 5.1 2.9 7.6 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tropomyosin_1 PF12718.7 KXZ52057.1 - 2.3 8.4 16.2 0.068 13.3 4.7 2.7 2 1 0 3 3 3 0 Tropomyosin like DASH_Spc19 PF08287.11 KXZ52057.1 - 6.7 6.6 11.8 2.6 7.9 0.9 3.2 2 1 1 3 3 3 0 Spc19 Fez1 PF06818.15 KXZ52057.1 - 7.9 6.9 13.6 2.5 8.5 10.5 1.8 2 1 0 2 2 2 0 Fez1 SNARE_assoc PF09335.11 KXZ52058.1 - 6.7e-09 36.3 1.4 6.7e-09 36.3 1.4 2.8 3 0 0 3 3 3 1 SNARE associated Golgi protein PSD5 PF07637.11 KXZ52058.1 - 0.34 11.3 0.2 0.34 11.3 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) Rit1_C PF17184.4 KXZ52060.1 - 2.2e-39 135.5 0.0 2.6e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Rit1 N-terminal domain Rit1_C PF17184.4 KXZ52061.1 - 1.1e-27 97.2 0.0 9.7e-26 90.8 0.0 2.1 1 1 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KXZ52061.1 - 4e-15 56.1 0.0 7.6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain DSPc PF00782.20 KXZ52061.1 - 4.1 7.2 8.2 0.055 13.3 0.5 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Metalloenzyme PF01676.18 KXZ52062.1 - 3.3e-86 288.7 0.0 3.8e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 KXZ52062.1 - 2.5e-58 197.1 0.0 5.2e-58 196.0 0.0 1.5 2 0 0 2 2 2 1 BPG-independent PGAM N-terminus (iPGM_N) PglZ PF08665.12 KXZ52062.1 - 0.069 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 PglZ domain DUF3659 PF12396.8 KXZ52062.1 - 0.12 12.3 0.6 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Sel1 PF08238.12 KXZ52063.1 - 1.6e-06 28.6 0.2 2.9e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 Sel1 repeat ISN1 PF06437.11 KXZ52063.1 - 0.18 10.7 0.0 0.22 10.4 0.0 1.0 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase DUF3707 PF12499.8 KXZ52064.1 - 3.7e-32 111.8 0.0 4.7e-10 40.2 0.0 3.5 3 1 1 4 4 4 3 Pherophorin His_Phos_1 PF00300.22 KXZ52065.1 - 1.9e-08 34.3 0.0 2.2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_90 PF05686.12 KXZ52066.1 - 2.8e-20 72.6 0.0 5.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXZ52066.1 - 0.039 14.3 0.2 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyoxalase_6 PF18029.1 KXZ52066.1 - 0.18 12.6 3.8 1.3 9.8 0.0 3.3 3 0 0 3 3 3 0 Glyoxalase-like domain Calmodulin_bind PF07887.11 KXZ52067.1 - 4.3e-14 52.5 0.0 1.6e-12 47.3 0.0 2.5 1 1 0 1 1 1 1 Calmodulin binding protein-like DUF1454 PF07305.12 KXZ52067.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) GTP_EFTU PF00009.27 KXZ52069.1 - 2.2e-17 63.3 0.0 4.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXZ52069.1 - 0.0022 18.3 0.2 0.0064 16.9 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KXZ52069.1 - 0.061 13.2 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KXZ52070.1 - 1.7e-36 125.8 0.0 2.5e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ52070.1 - 3.1e-08 33.8 0.7 0.0015 18.4 0.2 2.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ52070.1 - 6.5e-05 22.5 0.1 0.022 14.2 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain TOBE_2 PF08402.10 KXZ52070.1 - 0.00033 20.8 0.0 0.00084 19.5 0.0 1.8 1 0 0 1 1 1 1 TOBE domain AAA_16 PF13191.6 KXZ52070.1 - 0.00033 21.1 0.3 0.00066 20.1 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXZ52070.1 - 0.00062 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KXZ52070.1 - 0.002 18.3 0.0 0.0046 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ52070.1 - 0.0029 17.9 0.0 0.0061 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXZ52070.1 - 0.0037 17.2 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KXZ52070.1 - 0.0054 17.3 0.0 0.011 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXZ52070.1 - 0.01 15.5 0.1 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXZ52070.1 - 0.014 15.8 0.0 0.074 13.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KXZ52070.1 - 0.015 15.6 0.1 0.076 13.3 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KXZ52070.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KXZ52070.1 - 0.028 14.4 0.3 0.061 13.2 0.2 1.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KXZ52070.1 - 0.042 13.6 0.0 0.099 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXZ52070.1 - 0.043 14.4 0.1 0.11 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXZ52070.1 - 0.067 13.2 0.3 0.31 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 KXZ52070.1 - 0.09 11.6 0.6 1.4 7.6 0.1 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 KXZ52070.1 - 0.1 12.8 0.2 0.33 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXZ52070.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KXZ52070.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KXZ52070.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KXZ52070.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PSII_BNR PF14870.6 KXZ52071.1 - 5.2e-127 423.3 1.3 6.1e-127 423.0 1.3 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 KXZ52071.1 - 6.9e-10 38.3 0.0 0.036 12.9 0.0 3.2 2 2 1 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 KXZ52071.1 - 5.4e-09 34.7 3.5 0.29 11.3 0.0 5.0 3 0 0 3 3 3 3 BNR/Asp-box repeat PsbQ PF05757.11 KXZ52071.1 - 0.0029 17.4 0.1 0.0045 16.8 0.1 1.2 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) BNR_6 PF15899.5 KXZ52071.1 - 0.11 12.6 2.5 0.26 11.5 0.3 2.8 2 0 0 2 2 2 0 BNR-Asp box repeat Caleosin PF05042.13 KXZ52072.1 - 2.4e-54 183.8 0.0 8e-49 165.8 0.0 2.1 2 0 0 2 2 2 2 Caleosin related protein Ribosomal_S27 PF01599.19 KXZ52073.1 - 1.4e-25 89.2 2.6 2.2e-25 88.6 2.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 KXZ52073.1 - 2.3e-17 62.5 0.0 4.8e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXZ52073.1 - 4.5e-05 23.2 0.2 8.8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXZ52073.1 - 0.019 15.3 0.7 0.057 13.8 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain Zn_ribbon_SprT PF17283.2 KXZ52073.1 - 0.063 13.2 0.5 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DUF2318 PF10080.9 KXZ52073.1 - 0.077 13.1 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF2397 PF09660.10 KXZ52073.1 - 0.14 11.0 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF3797 PF12677.7 KXZ52073.1 - 0.18 11.7 1.0 10 6.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zinc_ribbon_4 PF13717.6 KXZ52073.1 - 0.38 10.7 2.5 5.8 6.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 KXZ52073.1 - 0.48 10.2 5.6 4.3 7.2 4.2 2.6 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KXZ52073.1 - 1.6 8.6 6.7 14 5.6 1.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 KXZ52073.1 - 1.7 9.1 4.6 4.5 7.7 4.6 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar GDA1_CD39 PF01150.17 KXZ52074.1 - 4.2e-91 305.7 0.0 5.1e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RC-P840_PscD PF10657.9 KXZ52074.1 - 0.03 14.4 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD U1snRNP70_N PF12220.8 KXZ52075.1 - 9.9 6.9 9.5 0.63 10.7 0.5 2.8 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Methyltr_RsmB-F PF01189.17 KXZ52076.1 - 2.8e-71 239.3 0.0 4.7e-71 238.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KXZ52076.1 - 1.8e-08 34.8 0.0 5.3e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KXZ52076.1 - 0.00028 21.1 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KXZ52076.1 - 0.00042 20.1 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FTA4 PF13093.6 KXZ52076.1 - 0.059 13.2 2.7 1.8 8.4 0.2 2.5 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sugar_tr PF00083.24 KXZ52077.1 - 5.6e-20 71.6 21.9 1.5e-15 57.0 9.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXZ52077.1 - 5.9e-20 71.5 39.4 1.7e-14 53.5 12.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyltransferase PF01553.21 KXZ52078.1 - 9.9e-16 57.6 0.1 1.7e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase tRNA-synt_2b PF00587.25 KXZ52079.1 - 1.1e-37 129.7 0.0 1.9e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXZ52079.1 - 5.3e-19 68.2 2.8 8.5e-19 67.5 0.5 2.3 3 0 0 3 3 3 1 Anticodon binding domain TGS PF02824.21 KXZ52079.1 - 1.3e-12 47.6 0.0 2.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KXZ52079.1 - 2.1e-08 34.1 0.0 3.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3079 PF11278.8 KXZ52080.1 - 0.0048 16.7 0.2 0.0082 15.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3079) Acetyltransf_1 PF00583.25 KXZ52081.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ52081.1 - 0.0016 18.8 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ52081.1 - 0.0027 17.6 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ52081.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Helicase_C_2 PF13307.6 KXZ52082.1 - 0.048 13.8 0.3 0.11 12.7 0.1 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain tRNA_int_end_N2 PF12928.7 KXZ52082.1 - 0.16 12.1 0.6 0.64 10.2 0.6 1.9 1 1 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Ion_trans PF00520.31 KXZ52083.1 - 1.5e-18 66.9 12.0 2.1e-18 66.4 11.8 1.3 1 1 0 1 1 1 1 Ion transport protein WD40 PF00400.32 KXZ52083.1 - 1.2e-05 26.0 13.7 4.4e-05 24.1 0.4 6.2 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ52083.1 - 0.02 15.2 0.1 1.2 9.5 0.1 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ52083.1 - 0.028 13.4 2.0 1.4 7.8 0.1 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LPMO_10 PF03067.15 KXZ52084.1 - 6.7e-15 56.3 6.0 4.7e-14 53.5 6.0 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading TIR_2 PF13676.6 KXZ52085.1 - 4.9e-11 43.3 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KXZ52085.1 - 6.6e-07 29.3 0.1 1.2e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain zf-UBP_var PF17807.1 KXZ52085.1 - 0.097 12.4 6.7 0.034 13.9 1.3 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger RVT_1 PF00078.27 KXZ52086.1 - 9.2e-38 130.0 0.0 1.6e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HIT PF01230.23 KXZ52089.1 - 9.5e-29 100.0 0.0 1.2e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXZ52089.1 - 7.1e-23 81.3 0.0 8.9e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ribosomal_S13 PF00416.22 KXZ52090.1 - 7.5e-51 171.8 0.9 8.7e-51 171.6 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 KXZ52090.1 - 0.015 15.7 0.3 0.03 14.8 0.3 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 FbpA PF05833.11 KXZ52090.1 - 0.15 10.8 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L10 PF00466.20 KXZ52091.1 - 3.4e-17 62.4 0.0 7.8e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 DUF1323 PF07037.11 KXZ52091.1 - 0.093 13.1 0.2 0.25 11.7 0.0 1.8 2 1 0 2 2 2 0 Putative transcription regulator (DUF1323) Ribosomal_S8e PF01201.22 KXZ52092.1 - 1.8e-53 180.4 1.1 2.3e-53 180.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e CinA PF02464.17 KXZ52092.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Competence-damaged protein DUF1676 PF07898.13 KXZ52092.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Chloroa_b-bind PF00504.21 KXZ52093.1 - 1.6e-49 168.5 0.2 2.1e-49 168.1 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RVT_3 PF13456.6 KXZ52094.1 - 1.3e-29 102.5 0.0 1.8e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like Cauli_VI PF01693.16 KXZ52094.1 - 3.8e-20 71.9 0.6 6.3e-20 71.2 0.6 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin RNase_H PF00075.24 KXZ52094.1 - 7e-08 32.8 0.0 1.2e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 RNase H FAST_1 PF06743.15 KXZ52096.1 - 2.2e-10 40.3 1.7 0.23 11.4 0.2 6.5 5 1 2 7 7 7 5 FAST kinase-like protein, subdomain 1 DNA_methylase PF00145.17 KXZ52097.1 - 1.1e-18 67.7 0.0 5e-10 39.2 0.0 2.6 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase BAH PF01426.18 KXZ52097.1 - 0.019 14.8 0.0 18 5.2 0.0 3.5 3 0 0 3 3 3 0 BAH domain Alpha-amylase_C PF02806.18 KXZ52098.1 - 1.3e-18 67.3 0.1 1.9e-17 63.5 0.1 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KXZ52098.1 - 4.2e-13 49.4 0.1 1e-12 48.2 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KXZ52098.1 - 5.8e-13 49.1 0.5 7.4e-10 38.9 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KXZ52098.1 - 0.23 10.5 0.0 0.36 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Mito_carr PF00153.27 KXZ52099.1 - 7.4e-78 256.6 2.0 6.8e-25 86.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXZ52099.1 - 0.0052 16.0 3.8 0.5 9.5 0.1 3.2 2 1 1 3 3 3 2 Gammaproteobacterial serine protease EutK_C PF16365.5 KXZ52099.1 - 0.025 14.6 0.5 4.1 7.5 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilization protein EutK C-terminus WD40 PF00400.32 KXZ52100.1 - 5e-110 356.3 44.0 7.9e-10 39.2 0.0 14.9 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ52100.1 - 1.6e-33 114.9 0.0 0.0018 18.6 0.0 11.3 5 3 6 12 12 12 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ52100.1 - 3.7e-20 72.2 2.6 0.00059 18.9 0.0 9.2 5 3 7 12 12 12 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KXZ52100.1 - 3.8e-07 29.7 0.7 5.7 6.7 0.0 6.6 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature PD40 PF07676.12 KXZ52100.1 - 6.7e-07 29.1 0.0 25 4.9 0.0 6.8 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KXZ52100.1 - 1.7e-05 24.8 0.0 9.8 6.0 0.0 5.3 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXZ52100.1 - 2.9e-05 22.8 0.1 0.72 8.3 0.0 3.8 4 1 1 5 5 5 2 Cytochrome D1 heme domain Nup160 PF11715.8 KXZ52100.1 - 6.7e-05 21.7 10.5 0.51 8.9 0.1 7.0 7 2 2 9 9 9 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXZ52100.1 - 0.00059 19.3 7.5 3.5 6.9 0.0 6.4 3 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.12 KXZ52100.1 - 0.00078 19.4 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain NHL PF01436.21 KXZ52100.1 - 0.0049 16.8 0.4 0.15 12.2 0.0 3.7 3 0 0 3 3 2 1 NHL repeat AAA_16 PF13191.6 KXZ52100.1 - 0.029 14.7 0.2 0.029 14.7 0.2 2.4 3 0 0 3 3 3 0 AAA ATPase domain PI-PLC-X PF00388.19 KXZ52101.1 - 3.2e-47 159.8 0.0 6.9e-47 158.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXZ52101.1 - 4.1e-27 94.8 0.5 9.8e-27 93.6 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KXZ52101.1 - 6.2e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain CDC45 PF02724.14 KXZ52102.1 - 4.8e-121 405.1 0.0 2.7e-119 399.3 0.0 2.0 1 1 0 1 1 1 1 CDC45-like protein Arm_vescicular PF18770.1 KXZ52102.1 - 0.013 15.4 0.2 0.036 14.0 0.2 1.8 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor FliG_M PF14841.6 KXZ52104.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 FliG middle domain KASH_CCD PF14662.6 KXZ52105.1 - 0.0042 16.9 7.4 0.0042 16.9 7.4 3.1 1 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 KXZ52105.1 - 0.014 14.1 7.9 0.0051 15.5 4.4 1.8 2 0 0 2 2 2 0 AAA domain FlxA PF14282.6 KXZ52105.1 - 0.022 14.7 0.2 0.022 14.7 0.2 3.1 3 0 0 3 3 3 0 FlxA-like protein DUF4407 PF14362.6 KXZ52105.1 - 0.03 13.7 27.0 0.87 8.9 3.1 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4407) DUF4614 PF15391.6 KXZ52105.1 - 0.085 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) YabA PF06156.13 KXZ52105.1 - 2.5 8.8 11.5 7.7 7.2 0.5 3.8 2 2 0 2 2 2 0 Initiation control protein YabA NYD-SP28_assoc PF14775.6 KXZ52105.1 - 5.3 7.2 7.2 3.2 7.9 0.3 3.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain TYA PF01021.19 KXZ52106.1 - 0.08 13.3 4.6 0.17 12.2 4.6 1.5 1 0 0 1 1 1 0 TYA transposon protein RSN1_7TM PF02714.15 KXZ52107.1 - 0.031 13.6 0.3 0.065 12.5 0.1 1.6 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate Helicase_C PF00271.31 KXZ52109.1 - 5.5e-07 29.9 0.0 6e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HlyIII PF03006.20 KXZ52110.1 - 2.4e-12 47.1 16.8 3e-12 46.8 16.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3636 PF12331.8 KXZ52110.1 - 0.18 11.6 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Helicase_C PF00271.31 KXZ52111.1 - 6.5e-05 23.2 0.1 0.023 15.1 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DUF1952 PF09189.10 KXZ52111.1 - 0.025 14.4 0.1 0.062 13.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) DUF2722 PF10846.8 KXZ52111.1 - 0.27 10.1 6.3 0.37 9.7 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 KXZ52111.1 - 0.29 11.1 8.8 0.41 10.6 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXZ52111.1 - 1.4 8.5 11.1 2 8.0 11.1 1.1 1 0 0 1 1 1 0 Spt20 family SIP PF04954.13 KXZ52111.1 - 9.8 6.7 9.7 14 6.3 0.1 3.3 4 0 0 4 4 4 0 Siderophore-interacting protein Herpes_capsid PF06112.11 KXZ52113.1 - 0.016 15.3 4.1 0.016 15.3 4.1 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Methyltransf_29 PF03141.16 KXZ52114.1 - 0.97 7.9 2.4 1.3 7.5 2.4 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SNF2_N PF00176.23 KXZ52116.1 - 7.9e-47 159.7 0.0 1.4e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KXZ52116.1 - 0.00035 20.6 0.0 0.00058 19.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ank_2 PF12796.7 KXZ52117.1 - 2.4e-11 44.0 1.1 0.0065 17.0 0.0 5.1 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ52117.1 - 2.5e-10 40.7 8.3 1.3 9.7 0.0 9.4 6 4 5 11 11 11 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ52117.1 - 0.00012 22.2 9.8 14 6.7 0.0 9.0 11 0 0 11 11 11 1 Ankyrin repeat Ank_5 PF13857.6 KXZ52117.1 - 0.0021 18.3 9.1 3.1 8.2 0.0 5.6 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Glyoxalase_4 PF13669.6 KXZ52117.1 - 0.016 15.5 0.2 0.46 10.8 0.0 2.9 2 1 1 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ATX_III PF08098.11 KXZ52117.1 - 8.3 6.5 12.0 10 6.2 1.4 4.1 3 0 0 3 3 3 0 Anemonia sulcata toxin III family PI-PLC-Y PF00387.19 KXZ52118.1 - 7.1e-25 87.6 0.1 1.2e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.19 KXZ52118.1 - 1.2e-12 47.7 0.0 1.7e-07 31.0 0.1 2.3 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, X domain C2 PF00168.30 KXZ52118.1 - 4.7e-09 36.5 0.0 0.0038 17.5 0.0 2.6 1 1 1 2 2 2 2 C2 domain PsbQ PF05757.11 KXZ52118.1 - 0.78 9.4 4.4 1.3 8.7 4.4 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) RT_RNaseH_2 PF17919.1 KXZ52120.1 - 8.2e-27 93.2 0.0 1.9e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ52120.1 - 8.8e-22 77.4 0.0 1.7e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KXZ52120.1 - 4.2e-12 46.0 0.0 7.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRP38_assoc PF12871.7 KXZ52120.1 - 8.6 7.0 55.0 4.8 7.9 35.0 3.7 3 1 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Peptidase_C14 PF00656.22 KXZ52122.1 - 0.00031 20.8 0.0 0.00041 20.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Phage_BR0599 PF09356.10 KXZ52122.1 - 0.11 12.8 0.0 15 6.0 0.0 2.3 1 1 1 2 2 2 0 Phage conserved hypothetical protein BR0599 HMGL-like PF00682.19 KXZ52123.1 - 1.6e-26 93.5 0.1 1.8e-26 93.3 0.1 1.1 1 0 0 1 1 1 1 HMGL-like SpoVS PF04232.12 KXZ52124.1 - 1.2e-43 146.7 1.3 2.9e-24 84.6 0.2 2.1 2 0 0 2 2 2 2 Stage V sporulation protein S (SpoVS) ARPC4 PF05856.12 KXZ52128.1 - 3.5e-67 225.2 0.0 3.9e-67 225.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Nop14 PF04147.12 KXZ52129.1 - 1.4e-176 589.4 0.0 3.1e-176 588.2 0.0 1.6 1 1 0 1 1 1 1 Nop14-like family Cloacin PF03515.14 KXZ52129.1 - 0.3 10.7 1.0 0.98 9.0 1.0 1.8 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain IFT57 PF10498.9 KXZ52129.1 - 0.62 9.0 3.4 5.2 5.9 0.0 2.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 PsbR PF04725.12 KXZ52130.1 - 6.2e-39 132.3 2.5 7.1e-39 132.1 2.5 1.1 1 0 0 1 1 1 1 Photosystem II 10 kDa polypeptide PsbR DUF5600 PF18150.1 KXZ52131.1 - 4.2e-26 91.6 0.3 2e-25 89.4 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 KXZ52131.1 - 1.8e-14 53.3 1.5 2.8e-14 52.7 0.6 1.8 2 0 0 2 2 2 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KXZ52131.1 - 1.8e-12 47.6 0.0 4.1e-10 40.0 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXZ52131.1 - 1.5e-08 34.7 0.0 6.8e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_5 PF13202.6 KXZ52131.1 - 0.0077 15.7 0.1 0.02 14.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.7 KXZ52131.1 - 0.016 15.1 0.0 0.068 13.1 0.0 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand AAA_24 PF13479.6 KXZ52131.1 - 0.077 12.7 0.3 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_7 PF13499.6 KXZ52131.1 - 0.098 13.1 0.0 0.43 11.1 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair AAA_28 PF13521.6 KXZ52131.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain EF-hand_1 PF00036.32 KXZ52131.1 - 0.16 11.6 0.0 0.79 9.4 0.0 2.3 1 0 0 1 1 1 0 EF hand PriCT_1 PF08708.11 KXZ52132.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) SelP_N PF04592.14 KXZ52132.1 - 0.2 11.0 6.9 0.24 10.8 6.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3042 PF11240.8 KXZ52134.1 - 0.47 10.5 2.0 1.3 9.1 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Metallophos PF00149.28 KXZ52138.1 - 4.7e-12 46.8 0.0 9.5e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Vps53_N PF04100.12 KXZ52139.1 - 1.4e-68 231.6 0.0 4.5e-47 160.8 0.0 2.1 2 0 0 2 2 2 2 Vps53-like, N-terminal ComR_TPR PF18710.1 KXZ52139.1 - 0.015 14.9 0.5 0.027 14.0 0.5 1.4 1 0 0 1 1 1 0 ComR tetratricopeptide XhlA PF10779.9 KXZ52139.1 - 0.048 13.9 0.2 0.33 11.2 0.3 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF1910 PF08928.10 KXZ52139.1 - 0.13 12.3 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Prominin PF05478.11 KXZ52139.1 - 0.2 9.6 1.1 0.29 9.1 1.1 1.1 1 0 0 1 1 1 0 Prominin DNA_methylase PF00145.17 KXZ52140.1 - 1.5e-28 100.1 0.0 1.5e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 KXZ52140.1 - 0.049 13.2 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase TRAM PF01938.20 KXZ52140.1 - 0.096 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 TRAM domain NESP55 PF06390.12 KXZ52140.1 - 1.3 8.6 7.9 1.4 8.4 2.0 2.7 3 0 0 3 3 3 0 Neuroendocrine-specific golgi protein P55 (NESP55) DNA_methylase PF00145.17 KXZ52141.1 - 2.3e-13 50.2 0.0 2.4e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase SP2 PF03014.14 KXZ52143.1 - 0.046 12.2 0.0 0.05 12.0 0.0 1.0 1 0 0 1 1 1 0 Structural protein 2 CAP_N PF01213.19 KXZ52143.1 - 0.81 9.1 7.4 0.87 9.0 7.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KXZ52143.1 - 2.5 8.2 8.9 3.8 7.6 8.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SAND PF01342.21 KXZ52144.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 SAND domain Mucin-like PF16058.5 KXZ52144.1 - 2.8 8.1 11.1 3.5 7.8 10.3 1.7 1 1 0 1 1 1 0 Mucin-like DNA_methylase PF00145.17 KXZ52145.1 - 4.8e-40 137.9 0.0 1e-30 107.3 0.0 3.1 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase BUD22 PF09073.10 KXZ52145.1 - 0.24 10.7 6.4 0.38 10.0 6.4 1.2 1 0 0 1 1 1 0 BUD22 Na_sulph_symp PF00939.19 KXZ52146.1 - 6.8e-113 378.2 36.3 8e-113 378.0 36.3 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXZ52146.1 - 4.9e-08 32.5 43.1 4.9e-08 32.5 43.1 2.6 1 1 1 2 2 2 1 Citrate transporter Rad60-SLD_2 PF13881.6 KXZ52147.1 - 1.1e-16 60.9 1.3 1.8e-10 40.9 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DnaJ-X PF14308.6 KXZ52148.1 - 4e-43 147.3 0.0 6.7e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 KXZ52148.1 - 2.8e-24 85.0 2.1 6.6e-24 83.8 2.1 1.7 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 KXZ52148.1 - 9e-08 32.4 0.2 9e-08 32.4 0.2 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain CemA PF03040.14 KXZ52149.1 - 1.2e-63 215.2 0.0 1.4e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 CemA family Mito_carr PF00153.27 KXZ52150.1 - 7.9e-62 205.2 0.2 9.8e-20 70.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Xan_ur_permease PF00860.20 KXZ52152.1 - 3.8e-25 88.4 24.6 9.7e-18 64.0 7.6 2.3 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 KXZ52152.1 - 0.0013 17.6 0.2 0.0013 17.6 0.2 3.5 4 0 0 4 4 4 2 Sulfate permease family Tir_receptor_C PF07489.11 KXZ52155.1 - 0.0054 16.7 1.2 0.0088 16.0 1.2 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) C-terminus PIF1 PF05970.14 KXZ52156.1 - 2.9e-24 85.9 1.8 9.1e-12 44.8 0.0 3.3 3 0 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 KXZ52156.1 - 2.4e-12 47.0 0.7 1.8e-10 40.9 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KXZ52156.1 - 3.8e-07 30.5 0.4 3.8e-07 30.5 0.4 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXZ52156.1 - 0.00078 19.7 0.3 0.0037 17.5 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ52156.1 - 0.016 15.6 0.1 0.016 15.6 0.1 2.8 4 0 0 4 4 4 0 AAA ATPase domain MutS_V PF00488.21 KXZ52161.1 - 7.6e-24 84.8 0.0 5.4e-14 52.6 0.0 2.4 2 1 0 2 2 2 2 MutS domain V MutS_I PF01624.20 KXZ52161.1 - 4.1e-11 43.1 0.0 9.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I GIY-YIG PF01541.24 KXZ52161.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 GIY-YIG catalytic domain AAA_29 PF13555.6 KXZ52161.1 - 0.043 13.6 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXZ52161.1 - 0.077 12.6 0.8 0.36 10.4 0.1 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KXZ52161.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KXZ52161.1 - 0.14 12.7 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KXZ52161.1 - 0.18 11.3 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain FXR_C1 PF16096.5 KXZ52161.1 - 0.25 11.6 0.8 0.61 10.3 0.8 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 AzlD PF05437.12 KXZ52162.1 - 1.2 9.3 7.3 2.6 8.3 1.9 2.7 2 1 1 3 3 3 0 Branched-chain amino acid transport protein (AzlD) Rib PF08428.10 KXZ52163.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Rib/alpha-like repeat SpmSyn_N PF17950.1 KXZ52164.1 - 0.24 11.6 0.0 0.38 11.0 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal AAA_12 PF13087.6 KXZ52165.1 - 7.2e-08 32.3 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ52165.1 - 1.9e-06 27.9 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ52165.1 - 0.00023 20.9 0.7 0.0058 16.4 0.7 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ52165.1 - 0.00094 19.5 0.0 0.0028 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DNAPolymera_Pol PF11590.8 KXZ52165.1 - 0.12 12.3 0.7 0.53 10.2 0.7 2.1 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol EF-hand_13 PF17958.1 KXZ52166.1 - 5.6e-26 90.2 0.0 2e-25 88.4 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KXZ52166.1 - 7.9e-21 74.3 0.5 1.5e-17 63.8 0.3 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ52166.1 - 1.6e-05 24.1 0.5 0.23 11.1 0.0 4.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXZ52166.1 - 9.8e-05 22.0 0.3 1.3 9.1 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KXZ52166.1 - 0.00011 21.6 0.1 0.015 14.8 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXZ52166.1 - 0.0063 16.3 0.3 1.3 8.9 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair UAA PF08449.11 KXZ52167.1 - 5.5e-65 219.5 18.3 6.2e-65 219.4 18.3 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXZ52167.1 - 2.5e-07 30.9 22.6 0.0005 20.3 12.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Cohesin_HEAT PF12765.7 KXZ52168.1 - 0.0094 16.2 0.3 0.015 15.6 0.3 1.4 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion DinB_2 PF12867.7 KXZ52168.1 - 0.45 11.0 2.9 7.2 7.1 2.9 2.0 1 1 0 1 1 1 0 DinB superfamily MA3 PF02847.17 KXZ52169.1 - 2.8e-25 88.5 0.2 5.5e-25 87.5 0.2 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KXZ52169.1 - 1.4e-12 47.7 0.1 4e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 MIF4G domain FAM199X PF15814.5 KXZ52169.1 - 4.4e-05 22.7 6.8 4.4e-05 22.7 6.8 2.2 2 0 0 2 2 2 1 Protein family FAM199X Nipped-B_C PF12830.7 KXZ52169.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus AF-4 PF05110.13 KXZ52169.1 - 1.4 6.9 41.9 0.11 10.5 4.7 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Ribosomal_L29 PF00831.23 KXZ52170.1 - 1.2e-06 28.3 4.2 5.5e-05 23.0 4.2 2.2 1 1 0 1 1 1 1 Ribosomal L29 protein NUC130_3NT PF08158.12 KXZ52170.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 NUC130/3NT domain ATP-synt PF00231.19 KXZ52171.1 - 4.1e-88 295.7 0.2 4.7e-88 295.5 0.2 1.0 1 0 0 1 1 1 1 ATP synthase HTH_20 PF12840.7 KXZ52171.1 - 0.037 14.1 0.3 0.084 13.0 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 KXZ52172.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family BATS PF06968.13 KXZ52173.1 - 3.7e-18 65.4 0.0 1.1e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KXZ52173.1 - 3.9e-16 59.9 0.0 6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXZ52173.1 - 0.02 15.2 0.6 0.039 14.2 0.6 1.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXZ52173.1 - 0.04 14.1 0.1 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain FA_hydroxylase PF04116.13 KXZ52174.1 - 3.9e-19 69.3 22.5 3.9e-19 69.3 22.5 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SnoaL_4 PF13577.6 KXZ52175.1 - 0.034 14.3 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 KXZ52176.1 - 1.5e-05 25.6 1.9 0.15 12.7 0.0 2.9 2 1 0 2 2 2 2 SnoaL-like domain SnoaL PF07366.12 KXZ52176.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PUB_1 PF18486.1 KXZ52176.1 - 0.076 12.9 0.1 0.47 10.4 0.1 2.2 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain DUF3140 PF11338.8 KXZ52177.1 - 4e-15 56.0 0.9 1.7e-07 31.6 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3140) FOXP-CC PF16159.5 KXZ52177.1 - 0.066 13.8 0.4 4.3 8.0 0.0 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain AMPK1_CBM PF16561.5 KXZ52178.1 - 2.5e-13 50.1 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PDZ_6 PF17820.1 KXZ52178.1 - 0.00079 19.2 0.0 0.00079 19.2 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KXZ52178.1 - 0.0052 17.1 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ52178.1 - 0.0085 16.4 0.1 0.021 15.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain TAF4 PF05236.14 KXZ52178.1 - 0.88 9.3 2.8 2.1 8.0 2.8 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PQ-loop PF04193.14 KXZ52179.1 - 1.4e-15 56.8 0.1 1.3e-08 34.4 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF952 PF06108.12 KXZ52180.1 - 2.9e-17 62.4 0.0 3.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Peptidase_M48 PF01435.18 KXZ52181.1 - 3.1e-14 53.2 1.3 3.1e-13 50.0 1.3 2.1 1 1 0 1 1 1 1 Peptidase family M48 Zn_peptidase PF04228.13 KXZ52181.1 - 0.00019 21.0 2.0 0.021 14.3 0.2 2.8 1 1 1 2 2 2 2 Putative neutral zinc metallopeptidase Peptidase_M78 PF06114.13 KXZ52181.1 - 0.02 14.8 0.4 0.073 13.0 0.4 1.9 1 1 0 1 1 1 0 IrrE N-terminal-like domain Peptidase_U49 PF10463.9 KXZ52181.1 - 0.25 11.1 2.8 3.2 7.5 2.8 2.4 1 1 0 1 1 1 0 Peptidase U49 PDT PF00800.18 KXZ52182.1 - 2.9e-64 216.3 0.0 1.2e-32 113.2 0.0 2.1 1 1 1 2 2 2 2 Prephenate dehydratase ACT PF01842.25 KXZ52182.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain SAND PF01342.21 KXZ52183.1 - 3.8e-12 45.7 1.5 1.1e-06 28.2 0.1 2.2 2 0 0 2 2 2 2 SAND domain Bee_toxin PF17454.2 KXZ52183.1 - 0.023 14.7 1.0 0.048 13.7 1.0 1.5 1 0 0 1 1 1 0 Honey bee toxin RL10P_insert PF17777.1 KXZ52184.1 - 2.9e-21 75.3 0.0 4.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KXZ52184.1 - 3.5e-21 75.2 0.1 5.5e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Gluconate_2-dh3 PF13618.6 KXZ52184.1 - 0.05 13.8 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Prefoldin PF02996.17 KXZ52185.1 - 9.9e-22 77.1 2.2 1.3e-21 76.7 1.2 1.7 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXZ52185.1 - 0.0032 17.4 2.1 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit Ribosomal_L31e PF01198.19 KXZ52185.1 - 0.045 14.0 0.1 0.18 12.0 0.0 2.0 2 1 0 2 2 2 0 Ribosomal protein L31e GST_N_3 PF13417.6 KXZ52189.1 - 2.6e-27 95.0 0.0 5.3e-12 46.0 0.0 3.2 3 0 0 3 3 3 3 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXZ52189.1 - 3.6e-11 43.2 0.0 9.1e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXZ52189.1 - 9e-10 38.8 0.0 2.9e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KXZ52189.1 - 0.0037 17.4 0.1 1.8 8.8 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin HMG_box PF00505.19 KXZ52190.1 - 3.9e-23 81.7 1.8 3.9e-23 81.7 1.8 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXZ52190.1 - 1.1e-16 61.2 2.0 1.1e-16 61.2 2.0 2.4 2 1 0 2 2 2 1 HMG-box domain Ribosomal_60s PF00428.19 KXZ52190.1 - 3.1e-05 24.5 16.7 3.1e-05 24.5 16.7 3.5 3 1 1 4 4 4 1 60s Acidic ribosomal protein CHDNT PF08073.12 KXZ52190.1 - 0.064 13.2 0.3 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 CHDNT (NUC034) domain Atg14 PF10186.9 KXZ52191.1 - 0.00061 19.0 3.3 0.00061 19.0 3.3 6.0 1 1 5 6 6 6 2 Vacuolar sorting 38 and autophagy-related subunit 14 SHIPPO-rpt PF07004.12 KXZ52193.1 - 0.00014 22.6 0.2 0.00014 22.6 0.2 6.3 6 1 0 6 6 6 4 Sperm-tail PG-rich repeat Ank_2 PF12796.7 KXZ52194.1 - 3.2e-23 82.1 0.3 3.5e-14 53.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ52194.1 - 3.3e-23 81.8 1.7 2.9e-15 56.4 0.3 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ52194.1 - 4.5e-22 77.5 1.4 9.9e-06 25.8 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXZ52194.1 - 4.8e-18 63.4 0.6 0.00014 22.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ52194.1 - 1.6e-17 63.3 5.8 1e-11 44.8 0.4 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) PGPGW PF09656.10 KXZ52195.1 - 0.098 12.2 0.1 0.098 12.2 0.1 1.9 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) DUF4227 PF14004.6 KXZ52195.1 - 0.38 10.8 2.4 6.9 6.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) Pro_isomerase PF00160.21 KXZ52196.1 - 3.8e-32 111.8 0.0 5.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAN_4 PF14295.6 KXZ52196.1 - 1.3e-08 34.7 8.9 2.4e-08 33.8 8.9 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXZ52196.1 - 0.031 14.2 1.0 0.058 13.4 1.0 1.4 1 0 0 1 1 1 0 PAN domain SEC-C PF02810.15 KXZ52196.1 - 3 7.9 10.3 0.11 12.4 3.2 2.3 2 0 0 2 2 2 0 SEC-C motif Adap_comp_sub PF00928.21 KXZ52197.1 - 2e-87 292.9 0.0 5.7e-87 291.4 0.0 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXZ52197.1 - 4.1e-09 36.5 1.7 6.8e-09 35.8 1.7 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3482 PF11981.8 KXZ52198.1 - 0.2 11.0 5.1 0.24 10.8 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Rick_17kDa_Anti PF05433.15 KXZ52198.1 - 2.4 8.1 29.2 1.5 8.7 9.3 2.5 1 1 2 3 3 3 0 Glycine zipper 2TM domain DUF2076 PF09849.9 KXZ52198.1 - 3.4 7.6 15.0 15 5.5 15.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_Omp PF13488.6 KXZ52198.1 - 5.2 7.2 29.1 26 4.9 29.1 2.1 1 1 1 2 2 2 0 Glycine zipper Pyr_redox_2 PF07992.14 KXZ52199.1 - 6.8e-62 209.3 2.2 8.4e-62 209.0 2.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXZ52199.1 - 1.6e-27 96.0 0.1 3.7e-27 94.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXZ52199.1 - 8.1e-18 64.8 0.4 2.9e-16 59.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ52199.1 - 0.00025 20.4 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ52199.1 - 0.0017 17.6 0.0 0.014 14.5 0.0 2.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KXZ52199.1 - 2.7 7.0 7.0 12 4.9 2.3 3.1 3 0 0 3 3 3 0 FAD binding domain Aldose_epim PF01263.20 KXZ52200.1 - 1.1e-81 274.5 0.0 1.3e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase cNMP_binding PF00027.29 KXZ52202.1 - 7.5e-26 90.0 0.1 4.5e-10 39.5 0.0 3.9 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Ank_2 PF12796.7 KXZ52203.1 - 4.4e-08 33.6 0.7 0.00028 21.4 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ52203.1 - 1e-05 25.5 1.8 0.39 11.4 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXZ52203.1 - 0.0042 17.4 5.2 0.45 10.9 0.4 3.4 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ52203.1 - 0.0069 16.9 1.4 2.6 8.7 0.5 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Motilin_assoc PF04643.12 KXZ52203.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Ank PF00023.30 KXZ52203.1 - 0.32 11.5 8.1 5.5 7.6 0.6 3.7 1 1 2 3 3 3 0 Ankyrin repeat UCR_14kD PF02271.16 KXZ52204.1 - 1.2e-26 92.6 0.8 1.4e-26 92.4 0.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit RAP PF08373.10 KXZ52205.1 - 0.0044 17.1 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain PAP2 PF01569.21 KXZ52206.1 - 2e-06 27.6 0.1 3.1e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily Radial_spoke PF04712.12 KXZ52208.1 - 0.002 17.2 2.8 0.0031 16.5 2.8 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein CLP1_P PF16575.5 KXZ52211.1 - 0.22 11.3 0.4 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF3225 PF11533.8 KXZ52215.1 - 0.075 12.7 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) HAMP PF00672.25 KXZ52216.1 - 0.28 11.6 1.7 9.5 6.7 0.1 2.4 2 0 0 2 2 2 0 HAMP domain Condensin2nSMC PF12422.8 KXZ52217.1 - 1.9e-32 112.5 0.0 5.4e-32 111.0 0.0 1.7 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 KXZ52217.1 - 1.1e-06 28.4 1.6 0.019 15.2 0.1 4.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KXZ52217.1 - 6e-06 26.6 1.2 0.15 12.4 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats Cohesin_HEAT PF12765.7 KXZ52217.1 - 0.0084 16.4 0.7 1.1 9.6 0.4 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion MMS19_N PF14500.6 KXZ52217.1 - 0.056 13.0 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 KXZ52217.1 - 0.073 13.6 3.3 8.2 7.1 0.1 3.7 3 0 0 3 3 3 0 HEAT-like repeat Smoothelin PF12510.8 KXZ52217.1 - 0.14 12.2 0.3 0.5 10.4 0.3 1.9 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein Ras PF00071.22 KXZ52218.1 - 3.3e-45 153.6 0.3 4.1e-45 153.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ52218.1 - 1.8e-30 105.6 0.2 2.6e-30 105.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ52218.1 - 6.3e-08 32.3 0.1 8e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXZ52218.1 - 0.00019 21.4 0.1 0.72 9.7 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KXZ52218.1 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KXZ52218.1 - 0.009 15.7 0.2 0.14 11.8 0.2 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ52218.1 - 0.0092 16.4 0.1 0.013 15.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KXZ52218.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KXZ52218.1 - 0.069 12.7 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 KXZ52218.1 - 0.11 12.0 0.9 11 5.5 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KXZ52218.1 - 0.15 11.8 1.5 3 7.6 0.1 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Nif11 PF07862.11 KXZ52218.1 - 0.16 12.3 0.4 29 5.0 0.0 3.2 3 0 0 3 3 3 0 Nif11 domain DLIC PF05783.11 KXZ52218.1 - 0.16 10.8 1.2 1.4 7.7 0.0 2.3 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) CAP_N PF01213.19 KXZ52218.1 - 1.8 8.0 4.8 2.7 7.4 4.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PFK PF00365.20 KXZ52219.1 - 1.2e-59 202.0 1.4 1.4e-59 201.7 1.4 1.1 1 0 0 1 1 1 1 Phosphofructokinase HSP70 PF00012.20 KXZ52220.1 - 2.2e-06 26.2 0.0 0.092 10.9 0.1 2.9 3 0 0 3 3 3 3 Hsp70 protein LRR_4 PF12799.7 KXZ52222.1 - 0.00084 19.7 0.0 4 8.0 0.0 5.0 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) CAP_N PF01213.19 KXZ52222.1 - 2.7 7.4 4.9 5.1 6.5 4.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Elong-fact-P_C PF09285.11 KXZ52223.1 - 4.6e-12 45.5 0.4 8.8e-12 44.6 0.4 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 KXZ52223.1 - 1.3e-11 44.3 0.0 2.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain PP2C_2 PF13672.6 KXZ52224.1 - 1.7e-11 44.2 0.0 3.8e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C DUF819 PF05684.12 KXZ52225.1 - 3.3e-38 131.7 24.3 5.1e-26 91.6 3.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF819) Pex2_Pex12 PF04757.14 KXZ52227.1 - 3.9e-09 36.4 0.2 1.2e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KXZ52227.1 - 1.4e-05 24.8 2.6 2.1e-05 24.3 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ52227.1 - 0.00016 21.4 2.4 0.00024 20.9 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ52227.1 - 0.00038 20.7 2.7 0.00064 20.0 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXZ52227.1 - 0.00071 19.4 2.1 0.001 18.9 2.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ52227.1 - 0.0048 16.9 5.0 0.0087 16.1 5.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger MFS_1 PF07690.16 KXZ52227.1 - 0.0076 15.2 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C3HC4_4 PF15227.6 KXZ52227.1 - 0.0085 16.2 3.4 0.013 15.6 3.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING CAP_N PF01213.19 KXZ52227.1 - 0.25 10.8 3.9 0.38 10.2 3.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KXZ52227.1 - 0.32 11.0 9.6 0.55 10.3 9.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Prok-RING_4 PF14447.6 KXZ52227.1 - 1.8 8.5 7.5 1.1 9.2 0.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 AhpC-TSA_2 PF13911.6 KXZ52229.1 - 8.5e-13 48.4 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXZ52229.1 - 0.00027 20.8 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ52229.1 - 0.039 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin Archease PF01951.16 KXZ52230.1 - 1.4e-36 125.8 0.1 1.6e-36 125.6 0.1 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) GTP_EFTU PF00009.27 KXZ52231.1 - 8.6e-46 155.9 0.1 1.4e-45 155.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXZ52231.1 - 5.6e-13 49.1 1.4 1.6e-11 44.4 0.3 3.0 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXZ52231.1 - 8e-11 42.2 0.0 3.6e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXZ52231.1 - 7.2e-06 26.1 0.0 0.0028 17.7 0.0 3.2 3 1 1 4 4 4 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KXZ52231.1 - 0.0059 16.5 0.3 0.023 14.6 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 YedD PF13987.6 KXZ52233.1 - 0.19 11.6 0.1 0.6 9.9 0.0 1.8 2 0 0 2 2 2 0 YedD-like protein PRIMA1 PF16101.5 KXZ52233.1 - 0.46 10.5 4.2 0.94 9.5 4.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PEX11 PF05648.14 KXZ52234.1 - 7.6e-30 104.0 0.1 9.1e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Prenyltransf PF01255.19 KXZ52235.1 - 1.9e-65 220.6 0.0 2.4e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PRT_C PF08372.10 KXZ52236.1 - 2.1e-19 69.8 0.0 3.8e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal NiFe-hyd_HybE PF11939.8 KXZ52236.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE AAA PF00004.29 KXZ52238.1 - 4.1e-35 121.1 0.0 6.4e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ52238.1 - 2.7e-07 31.1 3.1 0.00011 22.7 0.0 3.8 2 1 2 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 KXZ52238.1 - 5.7e-06 26.2 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KXZ52238.1 - 1.6e-05 24.6 0.1 4e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_24 PF13479.6 KXZ52238.1 - 2.3e-05 24.2 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ52238.1 - 2.7e-05 24.7 0.0 4.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ52238.1 - 3.5e-05 24.1 0.2 0.0032 17.8 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXZ52238.1 - 0.00023 21.2 0.1 0.0021 18.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXZ52238.1 - 0.00035 20.2 0.2 0.002 17.8 0.0 2.2 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 KXZ52238.1 - 0.00067 19.0 0.1 0.004 16.4 0.0 1.9 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 KXZ52238.1 - 0.00069 19.8 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXZ52238.1 - 0.0011 19.2 0.0 0.0035 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXZ52238.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KXZ52238.1 - 0.0015 18.6 0.0 0.0042 17.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 KXZ52238.1 - 0.0016 17.7 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TsaE PF02367.17 KXZ52238.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KXZ52238.1 - 0.0026 17.2 0.0 0.0068 15.8 0.0 1.6 1 1 1 2 2 2 1 KaiC TniB PF05621.11 KXZ52238.1 - 0.0042 16.5 0.0 0.25 10.7 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein T2SSE PF00437.20 KXZ52238.1 - 0.0047 16.0 0.0 0.013 14.5 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 KXZ52238.1 - 0.0062 16.1 0.0 0.015 14.8 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KXZ52238.1 - 0.0069 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase MCM PF00493.23 KXZ52238.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_2 PF07724.14 KXZ52238.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) SMC_N PF02463.19 KXZ52238.1 - 0.015 14.7 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KXZ52238.1 - 0.027 13.8 0.1 0.061 12.7 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KXZ52238.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KXZ52238.1 - 0.044 14.2 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXZ52238.1 - 0.068 13.1 0.0 0.93 9.4 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KXZ52238.1 - 0.09 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KXZ52238.1 - 0.11 12.2 0.1 4.6 7.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 KXZ52238.1 - 0.11 12.1 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 KXZ52238.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_29 PF13555.6 KXZ52238.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 KXZ52238.1 - 0.14 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_13 PF13166.6 KXZ52238.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXZ52238.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KXZ52238.1 - 0.2 11.8 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.22 KXZ52238.1 - 0.26 10.4 0.0 0.45 9.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 KXZ52239.1 - 1.9e-09 37.7 0.1 2.8e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXZ52239.1 - 4e-05 23.0 0.1 5.3e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KXZ52239.1 - 4.2e-05 23.4 1.6 6.8e-05 22.7 1.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ52239.1 - 0.00048 20.6 0.1 0.00082 19.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KXZ52239.1 - 0.00066 20.0 0.3 0.0011 19.3 0.3 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KXZ52239.1 - 0.022 14.1 0.1 0.04 13.2 0.1 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 KXZ52239.1 - 0.032 13.7 0.1 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KXZ52239.1 - 0.048 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXZ52239.1 - 0.052 12.9 0.5 0.091 12.1 0.5 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GvpD PF07088.11 KXZ52239.1 - 0.054 12.1 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein ResIII PF04851.15 KXZ52239.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXZ52239.1 - 0.15 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ52239.1 - 0.17 12.3 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 KXZ52239.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein UbiD PF01977.16 KXZ52239.1 - 0.21 10.4 0.4 0.37 9.6 0.2 1.4 2 0 0 2 2 2 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AAA_24 PF13479.6 KXZ52239.1 - 0.24 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DSS1_SEM1 PF05160.13 KXZ52241.1 - 4.1e-15 55.6 8.4 4.7e-15 55.4 8.4 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 KXZ52241.1 - 0.003 17.4 1.3 0.0033 17.3 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) SAND PF01342.21 KXZ52242.1 - 4.8e-05 23.0 0.8 0.0023 17.6 0.1 2.2 2 0 0 2 2 2 2 SAND domain Med3 PF11593.8 KXZ52242.1 - 1.7 7.7 6.5 2.4 7.3 6.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_M48 PF01435.18 KXZ52243.1 - 8.8e-11 41.9 0.1 3.1e-10 40.1 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M48 DNA_pol_A PF00476.20 KXZ52244.1 - 9.1e-86 288.3 0.0 1.2e-85 287.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A LRV PF01816.17 KXZ52244.1 - 0.0082 16.5 2.2 1.9 9.1 0.1 4.4 2 0 0 2 2 2 1 Leucine rich repeat variant SAND PF01342.21 KXZ52246.1 - 2.5e-06 27.1 4.0 0.0045 16.7 0.4 2.2 1 1 1 2 2 2 2 SAND domain Jas PF16135.5 KXZ52246.1 - 0.0035 17.5 3.5 0.01 16.0 0.2 2.3 1 1 1 2 2 2 1 TPL-binding domain in jasmonate signalling SAND PF01342.21 KXZ52247.1 - 7.2e-07 28.8 0.1 0.41 10.4 0.0 3.2 3 0 0 3 3 3 3 SAND domain zf-NADH-PPase PF09297.11 KXZ52247.1 - 0.0026 17.4 13.3 0.0086 15.7 1.3 3.6 3 0 0 3 3 3 2 NADH pyrophosphatase zinc ribbon domain zf-Mss51 PF13824.6 KXZ52247.1 - 0.73 10.0 14.0 0.077 13.1 1.6 3.0 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2072 PF09845.9 KXZ52247.1 - 1.2 9.4 2.5 0.96 9.7 0.2 1.9 2 0 0 2 2 2 0 Zn-ribbon containing protein Ysc84 PF04366.12 KXZ52249.1 - 9.6e-22 77.1 0.2 1.7e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Cation_ATPase_C PF00689.21 KXZ52251.1 - 1.2e-38 132.6 7.0 7.3e-20 71.4 0.5 2.9 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXZ52251.1 - 8.3e-24 84.1 8.7 8.6e-24 84.0 0.0 3.1 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 KXZ52251.1 - 3.6e-20 71.4 0.0 7.5e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KXZ52251.1 - 2.5e-15 57.4 0.1 4.1e-13 50.1 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ52251.1 - 1.3e-12 47.6 0.0 2.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXZ52251.1 - 0.0042 16.8 2.0 0.0075 16.0 1.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ52251.1 - 0.0088 16.5 0.8 0.022 15.2 0.2 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.32 KXZ52252.1 - 1.1e-16 59.0 0.0 0.001 18.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ52252.1 - 3.1e-16 59.6 0.0 7.6e-08 32.7 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ52252.1 - 6.8e-16 56.8 0.0 0.0071 16.2 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXZ52252.1 - 9.5e-12 43.8 0.0 1.6e-05 24.2 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KXZ52252.1 - 1.2e-07 31.5 0.0 0.26 11.2 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXZ52252.1 - 0.0033 17.7 0.0 3.9 7.8 0.0 2.5 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXZ52252.1 - 0.0076 16.2 0.1 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXZ52252.1 - 0.042 14.2 0.0 0.96 9.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 KXZ52252.1 - 0.19 12.0 0.6 9.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I domain Pkinase PF00069.25 KXZ52253.1 - 5.2e-12 45.7 0.1 8.9e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52253.1 - 5.7e-09 35.6 0.4 9.4e-09 34.9 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase ABC1 PF03109.16 KXZ52253.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Peptidase_M48 PF01435.18 KXZ52254.1 - 0.00013 21.8 0.5 0.00021 21.2 0.2 1.5 2 0 0 2 2 2 1 Peptidase family M48 DUF45 PF01863.17 KXZ52254.1 - 0.014 15.5 1.4 0.024 14.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Peptidase_M78 PF06114.13 KXZ52254.1 - 0.038 13.9 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain Peptidase_M48 PF01435.18 KXZ52255.1 - 5.7e-06 26.2 0.1 1.3e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 DUF45 PF01863.17 KXZ52255.1 - 0.0027 17.8 0.1 0.0037 17.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_M78 PF06114.13 KXZ52255.1 - 0.039 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 IrrE N-terminal-like domain ABA_WDS PF02496.16 KXZ52255.1 - 0.049 14.1 0.1 0.088 13.3 0.1 1.4 1 0 0 1 1 1 0 ABA/WDS induced protein DUF3810 PF12725.7 KXZ52255.1 - 0.23 10.8 0.1 0.28 10.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Robl_LC7 PF03259.17 KXZ52256.1 - 0.069 12.9 0.4 0.069 12.9 0.4 2.4 1 1 1 2 2 2 0 Roadblock/LC7 domain GET2 PF08690.10 KXZ52256.1 - 0.79 9.3 8.1 1.5 8.4 8.1 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1997 PF09366.10 KXZ52257.1 - 2.5e-37 128.4 0.0 3e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) RRM_1 PF00076.22 KXZ52258.1 - 5.2e-07 29.4 0.0 2.1e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ52258.1 - 0.08 12.8 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Aa_trans PF01490.18 KXZ52259.1 - 2.9e-55 187.6 14.5 4.2e-30 104.8 5.0 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXZ52259.1 - 2.7e-06 26.7 8.4 2.7e-06 26.7 8.4 2.3 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 KXZ52259.1 - 0.00011 21.1 1.4 0.00011 21.1 1.4 2.1 3 0 0 3 3 3 1 Spore germination protein PepSY_TM PF03929.16 KXZ52259.1 - 4 7.0 5.4 21 4.7 0.7 2.4 2 0 0 2 2 2 0 PepSY-associated TM region Chromate_transp PF02417.15 KXZ52259.1 - 4.2 7.5 20.7 0.84 9.8 1.0 3.3 2 1 0 2 2 2 0 Chromate transporter Myb_DNA-binding PF00249.31 KXZ52260.1 - 1.3e-22 79.6 1.1 3.2e-10 40.0 0.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ52260.1 - 3e-06 27.4 2.7 0.00043 20.5 0.0 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXZ52260.1 - 6e-06 26.1 7.9 0.0007 19.4 0.4 2.9 3 0 0 3 3 3 2 Myb DNA-binding like SlyX PF04102.12 KXZ52260.1 - 0.0033 18.0 5.8 0.0033 18.0 5.8 3.5 4 0 0 4 4 4 1 SlyX CENP-F_leu_zip PF10473.9 KXZ52260.1 - 0.015 15.4 1.5 0.015 15.4 1.5 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KXZ52260.1 - 0.034 14.4 2.0 0.12 12.7 2.0 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain NRBF2 PF08961.10 KXZ52260.1 - 0.04 13.5 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF287 PF03384.14 KXZ52260.1 - 0.085 13.3 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 APG6_N PF17675.1 KXZ52260.1 - 0.16 12.5 3.8 0.46 11.0 3.8 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KXZ52260.1 - 0.64 9.8 4.3 0.34 10.7 1.1 2.1 2 0 0 2 2 2 0 Septum formation initiator FlxA PF14282.6 KXZ52260.1 - 2.3 8.3 5.5 0.42 10.6 0.6 2.2 2 0 0 2 2 2 0 FlxA-like protein Ribosomal_S15 PF00312.22 KXZ52261.1 - 3.8e-25 87.9 0.3 5.1e-25 87.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 DUF2919 PF11143.8 KXZ52261.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) DAO PF01266.24 KXZ52262.1 - 3.2e-05 23.7 0.4 0.0031 17.1 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXZ52262.1 - 0.04 13.2 0.0 0.19 10.9 0.0 2.0 1 1 0 1 1 1 0 FAD binding domain Fer2_3 PF13085.6 KXZ52263.1 - 7.9e-26 90.2 0.4 1.4e-25 89.4 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KXZ52263.1 - 5.5e-09 36.5 3.6 5.5e-09 36.5 3.6 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXZ52263.1 - 3.9e-08 33.3 2.6 3.9e-08 33.3 2.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXZ52263.1 - 6e-08 33.0 12.0 1.1e-07 32.2 7.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KXZ52263.1 - 0.0016 18.4 0.9 0.0016 18.4 0.9 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KXZ52263.1 - 0.033 14.8 11.5 0.033 14.8 11.5 2.7 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KXZ52263.1 - 0.046 13.9 6.9 0.081 13.1 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXZ52263.1 - 0.069 14.1 8.6 2.1 9.3 1.4 3.0 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain SF3a60_bindingd PF12108.8 KXZ52263.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain IF4E PF01652.18 KXZ52263.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E Fer4_9 PF13187.6 KXZ52263.1 - 1.3 9.3 16.3 0.07 13.3 7.7 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain AAA_6 PF12774.7 KXZ52265.1 - 2.9e-125 417.6 0.0 4.5e-65 219.8 0.0 3.7 3 1 1 4 4 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ52265.1 - 6.3e-124 414.1 0.0 1.8e-123 412.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXZ52265.1 - 1e-94 316.7 0.0 2.3e-94 315.6 0.0 1.6 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KXZ52265.1 - 2.2e-86 289.9 0.0 2.1e-85 286.7 0.0 2.6 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KXZ52265.1 - 9.3e-77 257.1 0.7 5.5e-56 189.2 0.0 3.1 3 0 0 3 3 3 2 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ52265.1 - 3.6e-66 222.1 0.0 5.2e-62 208.6 0.0 3.7 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ52265.1 - 6.6e-48 162.6 0.0 1.3e-47 161.6 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXZ52265.1 - 3.8e-47 161.0 2.2 7.2e-47 160.1 2.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXZ52265.1 - 2.1e-22 79.4 0.0 3.2e-09 36.9 0.0 3.8 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KXZ52265.1 - 1.6e-17 63.8 0.1 0.00037 20.5 0.0 7.0 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KXZ52265.1 - 9.1e-17 61.3 0.0 5.7e-11 42.6 0.0 2.7 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ52265.1 - 3.8e-14 52.7 0.0 1e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KXZ52265.1 - 8e-12 45.7 0.0 0.054 13.9 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ52265.1 - 1.6e-08 35.1 13.2 8.7e-05 23.0 0.0 7.0 7 0 0 7 7 4 1 AAA ATPase domain AAA_22 PF13401.6 KXZ52265.1 - 1.4e-06 28.6 4.7 0.23 11.8 0.0 5.5 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.6 KXZ52265.1 - 4.1e-05 24.1 3.7 0.16 12.5 0.0 4.6 6 0 0 6 6 4 2 AAA domain AAA_30 PF13604.6 KXZ52265.1 - 5.7e-05 22.9 8.5 0.31 10.8 0.2 4.5 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.17 KXZ52265.1 - 0.00042 20.1 0.2 1.9 8.2 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXZ52265.1 - 0.00086 19.7 0.1 12 6.3 0.0 3.5 3 0 0 3 3 3 0 RNA helicase TsaE PF02367.17 KXZ52265.1 - 0.00092 19.2 3.2 0.59 10.1 0.1 3.6 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KXZ52265.1 - 0.0048 16.0 0.0 0.22 10.6 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.15 KXZ52265.1 - 0.005 16.8 0.3 4.6 7.1 0.0 3.3 3 0 0 3 3 3 1 Rad17 P-loop domain DUF815 PF05673.13 KXZ52265.1 - 0.005 16.0 0.2 0.28 10.3 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) NACHT PF05729.12 KXZ52265.1 - 0.0097 15.8 0.2 0.91 9.4 0.0 3.5 3 0 0 3 3 3 1 NACHT domain ZIP4_domain PF18292.1 KXZ52265.1 - 0.017 15.1 1.0 0.11 12.4 0.4 2.4 2 0 0 2 2 2 0 Zinc transporter ZIP4 domain Mg_chelatase PF01078.21 KXZ52265.1 - 0.021 14.2 1.3 2.7 7.3 0.0 3.5 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KXZ52265.1 - 0.022 15.1 13.9 0.025 14.9 0.1 4.4 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 KXZ52265.1 - 0.023 14.9 3.0 13 6.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 KXZ52265.1 - 0.026 14.7 8.0 13 5.9 0.1 5.5 5 0 0 5 5 5 0 AAA domain AAA_29 PF13555.6 KXZ52265.1 - 0.04 13.6 0.2 6.6 6.6 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_11 PF13086.6 KXZ52265.1 - 0.15 11.8 3.8 20 4.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain MMS22L_C PF14911.6 KXZ52265.1 - 1.7 7.7 5.0 5.3 6.0 0.4 2.3 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal NTPase_1 PF03266.15 KXZ52265.1 - 3.3 7.6 4.0 12 5.8 0.1 3.1 3 0 0 3 3 3 0 NTPase AAA_25 PF13481.6 KXZ52265.1 - 9 5.8 11.8 0.79 9.3 0.0 3.5 4 0 0 4 4 2 0 AAA domain FAST_1 PF06743.15 KXZ52268.1 - 0.0012 18.7 1.7 2.2 8.3 0.1 5.0 6 0 0 6 6 6 1 FAST kinase-like protein, subdomain 1 zf-CW PF07496.15 KXZ52269.1 - 7.3e-09 35.5 0.7 7.3e-09 35.5 0.7 2.6 3 0 0 3 3 3 1 CW-type Zinc Finger PWWP PF00855.17 KXZ52269.1 - 7.1e-08 32.8 0.1 1.3e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 KXZ52269.1 - 0.00014 21.6 16.4 0.0033 17.3 8.7 2.9 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H_2 PF13832.6 KXZ52269.1 - 0.24 11.6 3.2 0.65 10.2 3.2 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXZ52269.1 - 0.37 11.1 7.9 1 9.7 7.9 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain AAA_25 PF13481.6 KXZ52270.1 - 0.00027 20.6 0.3 0.0034 17.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain RNA12 PF10443.9 KXZ52270.1 - 0.24 10.1 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein DUF2742 PF10888.8 KXZ52271.1 - 0.043 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) Fasciclin PF02469.22 KXZ52272.1 - 2.6e-45 153.7 0.0 2.5e-16 60.0 0.0 4.2 3 1 1 4 4 4 4 Fasciclin domain TPR_14 PF13428.6 KXZ52272.1 - 1.2 10.2 6.5 3 8.9 0.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_methylase PF00145.17 KXZ52273.1 - 1e-48 166.4 0.0 6.3e-25 88.2 0.0 3.8 3 1 0 3 3 3 3 C-5 cytosine-specific DNA methylase BAH PF01426.18 KXZ52273.1 - 0.12 12.2 0.0 14 5.6 0.0 3.2 4 0 0 4 4 4 0 BAH domain zf-C3HC4_3 PF13920.6 KXZ52274.1 - 2.9e-06 27.0 0.1 4.8e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2009 PF09418.10 KXZ52275.1 - 2.5e-213 709.2 0.1 4.2e-213 708.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2009) ERM PF00769.19 KXZ52275.1 - 0.0047 16.8 16.5 0.0083 16.0 16.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Sulfotransfer_2 PF03567.14 KXZ52275.1 - 0.073 13.0 0.7 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Sulfotransferase family BAF1_ABF1 PF04684.13 KXZ52275.1 - 1.2 8.1 9.9 1.7 7.6 9.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Golgin_A5 PF09787.9 KXZ52275.1 - 1.6 8.1 9.9 2.6 7.4 9.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 IFT20 PF14931.6 KXZ52275.1 - 2.1 8.5 9.4 4.2 7.6 5.6 2.9 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 V_ATPase_I PF01496.19 KXZ52275.1 - 3.6 5.4 6.0 4.9 5.0 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Aminotran_3 PF00202.21 KXZ52276.1 - 2.5e-114 382.1 0.1 3e-114 381.8 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_M11 PF05548.11 KXZ52277.1 - 4.5e-42 144.3 0.0 7.4e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_3 PF13582.6 KXZ52277.1 - 0.028 14.9 0.0 0.069 13.7 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXZ52277.1 - 0.029 14.0 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KXZ52277.1 - 0.059 12.3 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 KXZ52277.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin ADP_ribosyl_GH PF03747.14 KXZ52278.1 - 7.6e-37 127.6 19.1 1.9e-28 100.0 14.7 3.0 1 1 1 2 2 2 2 ADP-ribosylglycohydrolase Ysc84 PF04366.12 KXZ52278.1 - 0.1 12.3 0.4 0.25 11.1 0.4 1.6 1 0 0 1 1 1 0 Las17-binding protein actin regulator BPS1 PF05633.11 KXZ52278.1 - 0.4 9.6 0.6 0.58 9.1 0.6 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related CCT PF06203.14 KXZ52279.1 - 2.3e-17 62.8 16.2 4e-17 62.0 16.2 1.4 1 0 0 1 1 1 1 CCT motif zf-B_box PF00643.24 KXZ52279.1 - 5.7e-07 29.6 11.1 8.6e-06 25.8 1.5 2.2 2 0 0 2 2 2 2 B-box zinc finger CCT_2 PF09425.10 KXZ52279.1 - 0.33 10.9 4.8 0.71 9.8 4.8 1.6 1 0 0 1 1 1 0 Divergent CCT motif Prok-RING_2 PF14445.6 KXZ52279.1 - 0.72 10.1 9.6 5.1 7.4 2.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 zf_CCCH_4 PF18345.1 KXZ52280.1 - 1.9e-10 40.4 34.5 0.00026 20.9 3.1 4.7 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 KXZ52280.1 - 2.9e-10 39.8 26.4 6.4e-05 22.8 0.5 4.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXZ52280.1 - 2.4e-08 33.6 14.9 1.3e-06 28.1 6.4 5.3 6 0 0 6 6 5 3 CCCH-type zinc finger zf-C3HC4 PF00097.25 KXZ52280.1 - 8.2e-08 32.0 2.4 2.8e-07 30.3 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ52280.1 - 1.2e-07 31.6 2.1 1.2e-07 31.6 2.1 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXZ52280.1 - 6.4e-07 29.6 3.6 6.4e-07 29.6 3.6 3.6 4 0 0 4 4 4 1 Ring finger domain Torus PF16131.5 KXZ52280.1 - 1.2e-06 29.2 20.3 0.0043 17.7 2.1 4.3 3 1 1 4 4 4 2 Torus domain zf-RING_UBOX PF13445.6 KXZ52280.1 - 1.8e-05 24.6 0.2 0.00014 21.8 0.0 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXZ52280.1 - 5.9e-05 22.8 3.0 5.9e-05 22.8 3.0 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXZ52280.1 - 0.00051 20.2 0.9 0.00051 20.2 0.9 2.1 2 0 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KXZ52280.1 - 0.0019 18.3 2.9 0.0019 18.3 2.9 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXZ52280.1 - 0.0022 17.8 1.4 0.012 15.5 1.4 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXZ52280.1 - 0.0037 17.1 0.4 0.0037 17.1 0.4 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ52280.1 - 0.006 16.8 4.2 0.006 16.8 4.2 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain Baculo_RING PF05883.11 KXZ52280.1 - 0.012 15.6 0.2 0.023 14.7 0.2 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_11 PF17123.5 KXZ52280.1 - 0.025 14.3 3.6 0.043 13.6 1.8 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-CCCH_2 PF14608.6 KXZ52280.1 - 3 8.4 31.5 0.17 12.4 1.0 4.6 4 1 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KXZ52280.1 - 7.4 6.8 19.5 0.037 14.3 3.1 3.3 3 1 0 3 3 3 0 Zinc-finger containing family Ribosomal_L21e PF01157.18 KXZ52281.1 - 2e-44 149.5 3.2 2.8e-44 149.1 3.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Rad51 PF08423.11 KXZ52282.1 - 8.3e-12 44.9 0.0 1.7e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Rad51 HATPase_c_2 PF13581.6 KXZ52282.1 - 0.0023 17.9 0.2 0.0053 16.7 0.1 1.6 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain NAD_binding_2 PF03446.15 KXZ52284.1 - 3.9e-37 127.8 0.6 6.8e-37 127.1 0.6 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXZ52284.1 - 3.4e-07 30.8 0.1 1.2e-06 29.0 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXZ52284.1 - 0.00038 20.1 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KXZ52284.1 - 0.00056 19.3 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 KXZ52284.1 - 0.0011 19.2 3.1 0.0052 17.0 3.1 2.2 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KXZ52284.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KXZ52284.1 - 0.0081 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KXZ52284.1 - 0.011 15.7 0.1 0.041 13.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF442 PF04273.13 KXZ52284.1 - 0.071 13.2 0.2 2.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Epimerase PF01370.21 KXZ52284.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXZ52284.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain mTERF PF02536.14 KXZ52287.1 - 9.4e-12 44.5 0.0 0.00076 18.5 0.0 3.6 3 1 2 5 5 5 4 mTERF MATH PF00917.26 KXZ52288.1 - 0.0027 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 MATH domain zf-C3HC4_3 PF13920.6 KXZ52289.1 - 0.0019 18.0 7.6 0.0029 17.4 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ52289.1 - 4.9 7.6 8.8 8.9 6.7 8.8 1.4 1 0 0 1 1 1 0 Ring finger domain PsbP PF01789.16 KXZ52290.1 - 1e-14 54.9 0.0 1.3e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 PsbP GDP_Man_Dehyd PF16363.5 KXZ52291.1 - 2.8e-36 125.6 0.0 3.4e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXZ52291.1 - 6e-35 120.8 0.0 7.8e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXZ52291.1 - 1.1e-07 31.3 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXZ52291.1 - 3.2e-05 23.2 0.0 0.00051 19.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1122 PF06557.11 KXZ52291.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) UPF0004 PF00919.20 KXZ52292.1 - 1.6e-27 95.4 0.1 3e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KXZ52292.1 - 5.1e-22 79.0 0.0 1.4e-21 77.6 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily TRAM_2 PF18693.1 KXZ52292.1 - 1.1e-14 54.3 0.0 3.5e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 TRAM domain TRAM PF01938.20 KXZ52292.1 - 0.094 12.7 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 TRAM domain GTP_EFTU PF00009.27 KXZ52293.1 - 2.7e-33 115.1 0.0 4.3e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXZ52293.1 - 1.1e-26 93.4 0.9 2.1e-26 92.4 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXZ52293.1 - 1.5e-15 57.3 6.6 3.3e-15 56.2 6.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KXZ52293.1 - 0.0038 17.1 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 KXZ52293.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain EPTP PF03736.17 KXZ52294.1 - 1.2e-07 31.5 2.9 0.28 11.2 0.1 4.6 5 0 0 5 5 5 3 EPTP domain GntP_permease PF02447.16 KXZ52294.1 - 4.4 5.9 6.7 0.41 9.3 1.5 1.7 2 1 0 2 2 2 0 GntP family permease FMO-like PF00743.19 KXZ52295.1 - 5.1e-15 54.9 0.0 5.4e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXZ52295.1 - 4.6e-06 26.1 0.0 6.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ52295.1 - 0.047 12.9 0.0 0.055 12.7 0.0 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ52295.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Exostosin PF03016.15 KXZ52297.1 - 7.3e-23 81.2 0.0 2.3e-13 50.0 0.0 2.1 1 1 1 2 2 2 2 Exostosin family EGF_2 PF07974.13 KXZ52297.1 - 5.5e-06 26.7 30.7 0.00084 19.7 14.9 2.8 2 0 0 2 2 2 2 EGF-like domain DUF5522 PF17653.1 KXZ52298.1 - 3.2e-20 71.8 4.5 5.5e-20 71.1 4.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Peripla_BP_2 PF01497.18 KXZ52298.1 - 4.2e-10 39.6 0.0 8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein NUDIX PF00293.28 KXZ52298.1 - 0.015 15.4 1.1 0.031 14.3 0.2 1.9 2 0 0 2 2 2 0 NUDIX domain Dynamin_M PF01031.20 KXZ52299.1 - 3e-35 121.8 0.0 3.9e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KXZ52299.1 - 1.4e-19 70.7 0.0 9.4e-19 68.1 0.0 2.2 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KXZ52299.1 - 5e-06 26.6 1.1 0.0002 21.4 1.1 2.8 1 1 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXZ52299.1 - 0.015 15.4 0.0 0.23 11.6 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KXZ52299.1 - 0.036 14.5 0.0 0.036 14.5 0.0 3.5 3 1 2 5 5 5 0 AAA ATPase domain AAA_29 PF13555.6 KXZ52299.1 - 0.044 13.5 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_M PF01031.20 KXZ52300.1 - 8.8e-29 100.6 0.0 3.1e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KXZ52300.1 - 3.8e-22 79.1 0.0 1.3e-21 77.3 0.0 2.0 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KXZ52300.1 - 3.2e-06 27.2 1.9 2.1e-05 24.6 1.9 2.3 1 1 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXZ52300.1 - 0.00012 22.2 0.0 0.066 13.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase PreAtp-grasp PF18604.1 KXZ52300.1 - 0.077 12.6 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Pre ATP-grasp domain AAA_16 PF13191.6 KXZ52300.1 - 0.43 10.9 3.2 0.79 10.1 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain Tim17 PF02466.19 KXZ52302.1 - 0.0085 16.5 3.2 0.053 13.9 0.7 2.3 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family RTX PF02382.15 KXZ52303.1 - 0.93 9.1 4.5 1.7 8.2 4.5 1.4 1 0 0 1 1 1 0 N-terminal domain in RTX protein BTB PF00651.31 KXZ52304.1 - 4.6e-09 36.5 0.0 1.3e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain LRR_8 PF13855.6 KXZ52307.1 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Leucine rich repeat RAP PF08373.10 KXZ52309.1 - 0.028 14.5 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 RAP domain FXR_C1 PF16096.5 KXZ52309.1 - 0.99 9.7 5.0 0.24 11.6 0.9 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Ras PF00071.22 KXZ52310.1 - 1.6e-53 180.6 0.1 1.8e-53 180.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ52310.1 - 3.3e-33 114.4 0.0 4.5e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ52310.1 - 7.3e-16 58.1 0.0 8.7e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXZ52310.1 - 1.3e-06 28.0 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXZ52310.1 - 2.3e-05 23.9 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXZ52310.1 - 2.6e-05 24.3 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXZ52310.1 - 0.00042 19.9 0.1 0.0016 18.0 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXZ52310.1 - 0.0017 18.8 0.1 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXZ52310.1 - 0.012 15.5 0.0 0.38 10.6 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KXZ52310.1 - 0.013 15.5 0.0 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 KXZ52310.1 - 0.017 14.8 0.0 0.052 13.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXZ52310.1 - 0.033 13.7 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 KXZ52310.1 - 0.054 12.7 0.4 3.9 6.5 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 KXZ52310.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 KXZ52310.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_33 PF13671.6 KXZ52310.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXZ52310.1 - 0.095 12.4 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ52310.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXZ52310.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Lar_N PF09861.9 KXZ52310.1 - 0.18 10.9 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Pkinase PF00069.25 KXZ52311.1 - 5.8e-31 107.8 0.0 8.1e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52311.1 - 1.1e-14 54.3 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LBP_BPI_CETP_C PF02886.17 KXZ52312.1 - 1.7e-11 44.0 0.0 4.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KXZ52312.1 - 1.6e-09 37.6 0.1 3.7e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain FXR_C1 PF16096.5 KXZ52312.1 - 0.021 15.0 1.6 0.042 14.0 1.6 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Sulfotransfer_4 PF17784.1 KXZ52312.1 - 0.083 12.7 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Sulfotransferase domain DUF826 PF05696.11 KXZ52312.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Vps39_2 PF10367.9 KXZ52313.1 - 3.4e-27 95.1 0.0 6.9e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KXZ52313.1 - 1e-12 48.2 0.0 2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KXZ52313.1 - 6e-06 26.2 0.0 0.056 13.3 0.0 3.7 4 0 0 4 4 4 2 Region in Clathrin and VPS TPR_2 PF07719.17 KXZ52313.1 - 5.5 7.4 16.2 11 6.5 0.3 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.23 KXZ52314.1 - 9.2e-106 353.5 0.3 4.4e-105 351.3 0.0 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ52314.1 - 2.7e-46 157.2 0.0 8.6e-46 155.6 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding FERM_M PF00373.18 KXZ52314.1 - 5.2e-19 68.8 0.7 5.2e-19 68.8 0.7 3.6 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.10 KXZ52314.1 - 4.9e-08 32.8 0.5 1.6e-07 31.1 0.1 2.1 2 0 0 2 2 2 1 FERM N-terminal domain MyTH4 PF00784.17 KXZ52314.1 - 0.0023 18.4 0.0 0.0079 16.7 0.0 1.9 1 0 0 1 1 1 1 MyTH4 domain Golgin_A5 PF09787.9 KXZ52314.1 - 0.003 17.1 6.0 0.003 17.1 6.0 4.1 3 1 0 3 3 3 1 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 KXZ52314.1 - 0.0079 16.4 16.9 0.0079 16.4 16.9 4.3 2 1 2 4 4 3 1 Tropomyosin like Phage_holin_3_6 PF07332.11 KXZ52314.1 - 0.26 11.3 3.5 0.47 10.5 1.9 2.3 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III YabA PF06156.13 KXZ52314.1 - 1.5 9.5 39.7 0.22 12.2 3.3 6.0 4 2 1 5 5 5 0 Initiation control protein YabA DUF732 PF05305.14 KXZ52314.1 - 4.3 7.8 7.3 7.1 7.1 0.9 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF732) FUSC PF04632.12 KXZ52314.1 - 6.3 5.2 22.7 18 3.7 0.0 2.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF3138 PF11336.8 KXZ52314.1 - 7.8 5.0 14.9 4.6 5.7 11.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3138) AAA_13 PF13166.6 KXZ52314.1 - 7.8 5.0 35.3 0.023 13.3 21.2 2.6 1 1 1 2 2 2 0 AAA domain mit_SMPDase PF14724.6 KXZ52315.1 - 0.0018 16.3 0.0 3.6 5.4 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial-associated sphingomyelin phosphodiesterase Myb_DNA-binding PF00249.31 KXZ52316.1 - 1.4e-07 31.6 0.1 2.3e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ52316.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1967 PF09269.11 KXZ52316.1 - 0.11 12.4 0.1 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Abhydrolase_1 PF00561.20 KXZ52317.1 - 2.9e-06 27.1 0.1 8.8e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXZ52317.1 - 0.00071 18.6 0.1 0.0012 17.8 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXZ52317.1 - 0.016 14.4 0.3 0.035 13.4 0.3 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 FA_desaturase PF00487.24 KXZ52318.1 - 6e-16 59.0 16.6 6e-16 59.0 16.6 1.6 1 1 1 2 2 2 1 Fatty acid desaturase SecE PF00584.20 KXZ52318.1 - 0.19 11.7 0.2 0.45 10.5 0.2 1.6 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF3953 PF13129.6 KXZ52319.1 - 0.24 11.2 1.2 0.98 9.2 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) LtrA PF06772.11 KXZ52319.1 - 0.83 8.8 12.2 0.023 13.9 5.0 1.8 1 1 1 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) UCR_Fe-S_N PF10399.9 KXZ52319.1 - 2 7.8 6.0 8 5.9 0.0 2.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ion_trans PF00520.31 KXZ52320.1 - 1.4e-19 70.4 11.1 2.2e-19 69.7 11.1 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXZ52320.1 - 1.4e-09 37.8 6.5 1.4e-09 37.8 6.5 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KXZ52320.1 - 6.1e-08 32.6 0.0 1.8e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain YtxH PF12732.7 KXZ52321.1 - 0.01 16.3 19.7 0.18 12.3 2.0 3.4 2 1 2 4 4 4 0 YtxH-like protein DUF883 PF05957.13 KXZ52321.1 - 0.017 15.7 20.2 0.12 13.0 6.3 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF885 PF05960.11 KXZ52321.1 - 0.018 14.7 5.5 0.023 14.3 5.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ApoLp-III PF07464.11 KXZ52321.1 - 0.032 14.3 6.1 0.52 10.4 1.2 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PhaP_Bmeg PF09602.10 KXZ52321.1 - 0.071 13.0 1.4 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Mitofilin PF09731.9 KXZ52321.1 - 0.093 11.6 13.7 0.11 11.3 13.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3584 PF12128.8 KXZ52321.1 - 0.18 9.3 12.2 0.2 9.1 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ApoO PF09769.9 KXZ52321.1 - 0.19 11.7 2.0 5.1 7.1 2.0 2.4 1 1 0 1 1 1 0 Apolipoprotein O T3SSipB PF16535.5 KXZ52321.1 - 0.21 12.1 15.8 0.43 11.1 15.7 1.5 1 1 0 1 1 1 0 Type III cell invasion protein SipB Apolipoprotein PF01442.18 KXZ52321.1 - 0.24 11.2 15.1 0.75 9.6 15.1 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phasin PF05597.11 KXZ52321.1 - 0.27 11.3 11.3 0.28 11.2 4.4 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pex19 PF04614.12 KXZ52321.1 - 0.34 10.7 7.7 0.41 10.4 7.7 1.2 1 0 0 1 1 1 0 Pex19 protein family Chlorosome_CsmC PF11098.8 KXZ52321.1 - 0.64 10.0 9.6 0.17 11.9 4.7 2.0 1 1 1 2 2 2 0 Chlorosome envelope protein C HisKA_3 PF07730.13 KXZ52321.1 - 0.81 10.2 6.4 2.7 8.6 0.5 2.9 3 1 0 3 3 2 0 Histidine kinase PDDEXK_6 PF04720.12 KXZ52321.1 - 1.1 9.2 6.5 1.3 8.9 6.5 1.3 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Plasmodium_Vir PF05795.11 KXZ52321.1 - 1.2 8.4 4.7 1.5 8.2 4.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF948 PF06103.11 KXZ52321.1 - 1.7 9.0 6.6 3.3 8.0 1.9 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MT0933_antitox PF14013.6 KXZ52321.1 - 3 8.2 23.2 5.6 7.3 10.4 4.2 3 2 0 3 3 3 0 MT0933-like antitoxin protein T3SS_basalb_I PF17001.5 KXZ52321.1 - 3.2 8.4 6.9 9.3 6.9 0.6 2.9 1 1 2 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI ISG65-75 PF11727.8 KXZ52321.1 - 3.3 6.9 15.3 5 6.3 14.9 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein Cdh1_DBD_1 PF18196.1 KXZ52321.1 - 5 7.5 9.2 2.5 8.4 0.9 2.2 1 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 T3SS_needle_F PF09392.10 KXZ52321.1 - 8.8 6.6 7.2 5.9 7.2 0.5 2.9 2 1 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Mod_r PF07200.13 KXZ52322.1 - 0.0096 16.0 0.4 0.011 15.8 0.4 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein CTP_transf_like PF01467.26 KXZ52323.1 - 2e-05 24.8 0.0 0.0012 19.0 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase-like CinA PF02464.17 KXZ52323.1 - 0.021 14.4 0.7 0.042 13.4 0.1 1.7 2 0 0 2 2 2 0 Competence-damaged protein FAD_syn PF06574.12 KXZ52323.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Herpes_capsid PF06112.11 KXZ52325.1 - 4.8 7.2 8.3 9.6 6.2 8.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Alkyl_sulf_dimr PF14863.6 KXZ52326.1 - 0.023 15.1 0.2 0.039 14.4 0.2 1.4 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Myb_CC_LHEQLE PF14379.6 KXZ52326.1 - 0.044 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Ank_5 PF13857.6 KXZ52327.1 - 1.2e-18 66.9 2.8 1.1e-07 32.0 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ52327.1 - 2.4e-17 63.3 0.0 1.5e-11 44.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ52327.1 - 2.8e-17 62.8 0.1 4.5e-08 33.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ52327.1 - 1.2e-16 60.3 3.9 5.5e-06 26.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXZ52327.1 - 3.9e-16 57.5 0.2 6.2e-05 23.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KXZ52328.1 - 2e-21 75.4 0.3 6.8e-06 26.3 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ52328.1 - 2.1e-17 63.2 0.0 4.8e-06 27.0 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ52328.1 - 2e-16 60.3 0.0 9.4e-10 38.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ52328.1 - 1.2e-15 57.3 0.6 1.1e-08 35.2 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ52328.1 - 1.8e-15 55.5 0.3 3.4e-05 23.9 0.0 4.4 4 1 0 4 4 4 3 Ankyrin repeat SBF_like PF13593.6 KXZ52329.1 - 1.2e-89 300.7 18.3 1.4e-89 300.5 18.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KXZ52329.1 - 1.9e-13 50.6 9.5 1.9e-13 50.6 9.5 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family TMEM132D_C PF15706.5 KXZ52329.1 - 0.086 12.6 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MTHFR PF02219.17 KXZ52329.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Cu2_monooxygen PF01082.20 KXZ52330.1 - 2.8e-18 66.4 0.0 5.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KXZ52330.1 - 2.3e-17 62.9 0.0 3.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 KXZ52330.1 - 8.1e-09 35.8 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 DOMON domain VMA21 PF09446.10 KXZ52330.1 - 0.02 15.0 0.2 0.064 13.4 0.2 1.9 1 0 0 1 1 1 0 VMA21-like domain PALP PF00291.25 KXZ52331.1 - 3.2e-48 164.7 2.8 3.5e-48 164.5 2.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase_Tyr PF07714.17 KXZ52333.1 - 5.5e-26 91.4 0.0 2.5e-25 89.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ52333.1 - 1.6e-24 86.7 0.0 5.6e-24 84.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ52333.1 - 0.0015 18.5 0.2 0.0072 16.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ52333.1 - 0.011 14.6 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CN_hydrolase PF00795.22 KXZ52334.1 - 2.8e-06 26.9 0.0 6.7e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2275 PF10039.9 KXZ52334.1 - 0.22 11.6 0.2 0.35 11.0 0.2 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Pkinase PF00069.25 KXZ52335.1 - 1.1e-27 97.0 0.0 3.3e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52335.1 - 1.5e-22 80.2 0.0 4.9e-18 65.3 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ52335.1 - 0.019 14.9 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ52335.1 - 0.28 9.9 0.0 0.41 9.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ52336.1 - 6.8e-11 42.0 0.0 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52336.1 - 1.8e-09 37.3 0.0 0.00048 19.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Bestrophin PF01062.21 KXZ52338.1 - 1.5e-43 149.3 0.1 1.9e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Prok-E2_C PF14459.6 KXZ52339.1 - 6.8 6.9 13.2 8.3 6.6 3.1 3.5 3 0 0 3 3 3 0 Prokaryotic E2 family C Ribonuc_L-PSP PF01042.21 KXZ52340.1 - 7e-28 97.1 0.1 7.7e-28 96.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ADP_ribosyl_GH PF03747.14 KXZ52342.1 - 1.5e-29 103.7 2.5 1.8e-29 103.4 2.5 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase EGF_2 PF07974.13 KXZ52343.1 - 0.0035 17.7 14.7 0.0035 17.7 14.7 2.0 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.24 KXZ52343.1 - 0.033 14.3 9.8 0.088 13.0 9.8 1.7 1 0 0 1 1 1 0 Laminin EGF domain Ribosomal_L1 PF00687.21 KXZ52345.1 - 3.9e-26 92.1 0.0 5.2e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ank_2 PF12796.7 KXZ52346.1 - 8.2e-12 45.5 0.1 0.024 15.2 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ52346.1 - 2.5e-09 37.5 3.5 0.91 10.2 0.0 6.8 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ52346.1 - 0.0012 19.2 0.3 2.3e+02 2.9 0.0 6.6 8 0 0 8 8 8 0 Ankyrin repeat WD40 PF00400.32 KXZ52347.1 - 1.7e-15 57.1 6.1 0.00059 20.6 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ52347.1 - 2.1e-07 31.1 0.2 0.0028 17.9 0.0 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXZ52347.1 - 0.043 14.3 0.4 1.5 9.4 0.0 3.4 2 1 1 3 3 3 0 PQQ-like domain T3SSipB PF16535.5 KXZ52349.1 - 3.6 8.1 20.4 5.2 7.5 8.9 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB LRR_4 PF12799.7 KXZ52351.1 - 0.002 18.5 2.8 0.021 15.2 0.5 3.3 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ52351.1 - 0.04 13.7 1.7 0.59 9.9 0.1 3.1 3 0 0 3 3 3 0 Leucine rich repeat GGDEF_2 PF17853.1 KXZ52352.1 - 0.083 13.2 6.7 0.13 12.5 6.7 1.5 1 1 0 1 1 1 0 GGDEF-like domain T3SSipB PF16535.5 KXZ52352.1 - 0.28 11.7 13.3 0.4 11.1 2.6 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB LprI PF07007.12 KXZ52352.1 - 0.41 11.3 11.1 0.092 13.4 1.8 2.1 2 0 0 2 2 2 0 Lysozyme inhibitor LprI Dynein_light PF01221.18 KXZ52352.1 - 1.5 9.2 3.4 1.5 9.2 0.1 2.0 2 0 0 2 2 2 0 Dynein light chain type 1 WEMBL PF05701.11 KXZ52352.1 - 1.7 7.3 20.7 0.6 8.7 6.1 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.11 KXZ52352.1 - 2.5 6.9 5.9 0.49 9.2 0.9 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein YscO PF07321.12 KXZ52352.1 - 4.2 7.3 22.8 0.21 11.5 9.8 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO TraV PF09676.10 KXZ52352.1 - 7.3 7.6 9.6 59 4.6 9.6 1.9 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Hist_deacetyl PF00850.19 KXZ52353.1 - 6.1e-67 226.3 0.0 7.8e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain FXR_C1 PF16096.5 KXZ52353.1 - 0.4 10.9 4.0 0.78 10.0 4.0 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Ank_2 PF12796.7 KXZ52354.1 - 4.1e-24 85.0 1.2 5.7e-11 42.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ52354.1 - 7.5e-21 73.9 11.5 4.2e-08 33.3 0.1 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ52354.1 - 4.8e-20 71.6 5.5 3.1e-10 40.4 0.3 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ52354.1 - 2.1e-18 64.5 6.7 0.0013 19.1 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat U-box PF04564.15 KXZ52354.1 - 2.9e-17 62.6 0.0 4.4e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 U-box domain Ank PF00023.30 KXZ52354.1 - 1.7e-15 56.7 10.1 0.0031 17.9 0.3 5.6 5 0 0 5 5 5 4 Ankyrin repeat zf-NOSIP PF15906.5 KXZ52354.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KXZ52354.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_12 PF13424.6 KXZ52355.1 - 2.9e-08 33.9 56.6 0.00013 22.2 7.0 6.5 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ52355.1 - 0.13 12.1 0.1 0.13 12.1 0.1 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 KXZ52356.1 - 2.6e-44 151.5 0.0 1.9e-31 109.2 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KXZ52356.1 - 1.2e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 KXZ52356.1 - 0.11 11.7 0.0 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class I and II Sacchrp_dh_NADP PF03435.18 KXZ52357.1 - 9.7e-06 25.9 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FxsA PF04186.13 KXZ52357.1 - 0.022 14.9 0.2 0.041 14.0 0.2 1.4 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein SDA1 PF05285.12 KXZ52362.1 - 5.8e-58 197.0 49.4 4.9e-56 190.6 44.9 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KXZ52362.1 - 1.4e-15 57.3 0.0 3.9e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Ubiq_cyt_C_chap PF03981.12 KXZ52362.1 - 0.19 11.8 6.3 6 6.9 2.1 3.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone DHHC PF01529.20 KXZ52363.1 - 4.7e-21 75.3 0.5 4.7e-21 75.3 0.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.25 KXZ52364.1 - 2.3e-43 148.4 0.0 1.2e-27 97.0 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52364.1 - 5.1e-21 75.1 0.0 3.6e-12 46.1 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ52364.1 - 0.016 15.2 0.1 0.89 9.4 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ52364.1 - 0.2 10.6 0.0 0.41 9.5 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 KXZ52365.1 - 8.9e-21 74.4 0.0 3.7e-19 69.1 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52365.1 - 5.4e-20 71.8 0.0 4.8e-16 58.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 KXZ52365.1 - 4.1e-12 45.7 15.5 2.5e-08 33.5 4.8 3.4 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KXZ52365.1 - 3.5e-11 43.1 11.9 0.0021 18.4 0.6 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) Kdo PF06293.14 KXZ52365.1 - 6.1e-06 25.7 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ52365.1 - 4e-05 23.7 10.6 0.0021 18.0 0.4 3.6 2 1 2 4 4 4 2 Phosphotransferase enzyme family RIO1 PF01163.22 KXZ52365.1 - 0.0033 17.1 0.0 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH_6_hur PF04655.14 KXZ52365.1 - 0.01 15.3 1.5 2 7.7 0.1 2.2 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Choline_kinase PF01633.20 KXZ52365.1 - 0.03 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KXZ52365.1 - 0.039 13.6 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LRR_9 PF14580.6 KXZ52365.1 - 0.087 12.3 2.3 0.89 9.0 1.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 KXZ52365.1 - 8.1 7.4 10.6 2.2e+02 3.0 0.2 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat DUF3707 PF12499.8 KXZ52366.1 - 2.6e-37 128.6 23.2 6.9e-19 68.8 6.4 2.1 2 0 0 2 2 2 2 Pherophorin Ion_trans PF00520.31 KXZ52367.1 - 3.3e-193 638.9 56.9 1.6e-53 181.5 11.0 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KXZ52367.1 - 3.7e-08 33.0 0.0 9.7e-08 31.7 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KXZ52367.1 - 0.00011 21.1 87.4 0.00021 20.1 1.3 11.2 8 4 2 10 10 10 6 Polycystin cation channel Ion_trans PF00520.31 KXZ52368.1 - 5.2e-227 749.6 74.0 2.2e-60 203.9 7.1 4.1 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KXZ52368.1 - 2.7e-08 33.4 0.0 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KXZ52368.1 - 0.00062 18.5 9.5 0.0014 17.4 2.4 11.0 8 4 2 10 10 10 6 Polycystin cation channel P2 PF07194.11 KXZ52368.1 - 0.071 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 P2 response regulator binding domain UMP1 PF05348.11 KXZ52369.1 - 1e-27 96.7 0.0 1.2e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase_Tyr PF07714.17 KXZ52371.1 - 1.9e-42 145.3 0.0 2.7e-34 118.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ52371.1 - 1.5e-40 139.3 0.0 2.4e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GAF_2 PF13185.6 KXZ52371.1 - 1e-05 25.9 0.0 0.075 13.3 0.0 2.9 2 0 0 2 2 2 2 GAF domain Kinase-like PF14531.6 KXZ52371.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXZ52371.1 - 0.028 13.8 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ52371.1 - 0.031 14.2 0.0 0.081 12.8 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family GAF PF01590.26 KXZ52371.1 - 0.053 14.2 0.0 5 7.8 0.0 2.6 2 0 0 2 2 2 0 GAF domain Autoind_bind PF03472.15 KXZ52371.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Autoinducer binding domain GCIP PF13324.6 KXZ52372.1 - 1.1e-14 54.6 0.1 7.2e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Grap2 and cyclin-D-interacting Cytomega_UL84 PF06284.11 KXZ52372.1 - 0.089 11.2 1.5 0.12 10.8 1.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein LSM PF01423.22 KXZ52373.1 - 1.7e-17 62.8 0.1 2.4e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXZ52373.1 - 0.0067 16.5 0.1 0.009 16.1 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.8 KXZ52373.1 - 0.059 13.3 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) RYDR_ITPR PF01365.21 KXZ52374.1 - 4e-27 95.0 0.0 1.7e-16 60.3 0.0 2.8 2 0 0 2 2 2 2 RIH domain Ins145_P3_rec PF08709.11 KXZ52374.1 - 2.1e-20 72.8 0.0 5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 KXZ52374.1 - 1.1e-17 63.7 1.0 1.1e-17 63.7 1.0 3.1 4 0 0 4 4 4 1 RyR and IP3R Homology associated MIR PF02815.19 KXZ52374.1 - 6e-05 23.0 0.0 0.0051 16.7 0.0 3.0 2 1 0 2 2 2 1 MIR domain V-ATPase_H_C PF11698.8 KXZ52374.1 - 0.0067 16.5 1.7 1.4 9.1 0.0 4.3 6 0 0 6 6 6 1 V-ATPase subunit H Ion_trans PF00520.31 KXZ52375.1 - 3e-08 33.2 6.3 4.4e-08 32.7 6.3 1.2 1 0 0 1 1 1 1 Ion transport protein Pkinase PF00069.25 KXZ52376.1 - 4.1e-67 226.3 0.0 5.9e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52376.1 - 7.2e-30 104.1 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ52376.1 - 7.5e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ52376.1 - 0.00026 20.4 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ52376.1 - 0.00083 18.2 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXZ52376.1 - 0.042 12.8 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF2854 PF11016.8 KXZ52377.1 - 1.3e-27 96.5 0.0 2.4e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) Pkinase_Tyr PF07714.17 KXZ52378.1 - 1.4e-31 109.7 0.0 1e-27 97.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ52378.1 - 4.2e-27 95.2 0.0 4.4e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ52378.1 - 7.3e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SOUL PF04832.12 KXZ52379.1 - 2.1e-42 145.2 0.0 2.6e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein DUF2358 PF10184.9 KXZ52379.1 - 1.3e-19 70.5 0.0 2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KXZ52379.1 - 1.1e-05 26.0 0.0 3.7e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like domain SOGA PF11365.8 KXZ52380.1 - 0.0095 17.0 5.8 0.0095 17.0 5.8 11.1 5 1 5 12 12 12 1 Protein SOGA MCM_OB PF17207.3 KXZ52381.1 - 7.3e-28 96.9 0.4 1.1e-27 96.4 0.4 1.2 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXZ52381.1 - 1.1e-09 38.6 1.2 1.8e-09 37.9 1.2 1.3 1 0 0 1 1 1 1 MCM AAA-lid domain MCM PF00493.23 KXZ52381.1 - 3.5e-05 23.0 0.0 6.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain Cobl PF09469.10 KXZ52381.1 - 0.22 11.8 0.1 0.43 10.9 0.1 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain LRR_4 PF12799.7 KXZ52382.1 - 0.0029 18.0 0.1 0.066 13.7 0.0 2.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) FliD_C PF07195.12 KXZ52384.1 - 0.12 11.8 0.9 0.18 11.2 0.9 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Fes1 PF08609.10 KXZ52384.1 - 0.36 11.7 9.5 0.82 10.6 9.5 1.6 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF913 PF06025.12 KXZ52384.1 - 0.42 9.5 1.2 0.58 9.1 1.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) dCache_1 PF02743.18 KXZ52384.1 - 1.4 8.6 3.0 2.1 8.1 3.0 1.2 1 0 0 1 1 1 0 Cache domain TPR_16 PF13432.6 KXZ52385.1 - 4.1e-13 49.7 17.7 1.1e-09 38.8 7.9 6.5 6 1 1 7 7 4 3 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KXZ52385.1 - 2.7e-11 43.1 9.8 4.9e-11 42.3 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 KXZ52385.1 - 6.4e-11 41.6 8.1 0.0001 22.0 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ52385.1 - 8.5e-11 41.1 9.9 0.0083 16.2 0.3 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ52385.1 - 7.2e-09 35.2 11.2 5.2e-06 26.0 2.8 3.3 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 KXZ52385.1 - 6.1e-06 26.6 2.2 6.1e-06 26.6 2.2 5.8 4 1 2 6 6 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ52385.1 - 1.1e-05 25.6 11.3 0.0037 17.5 0.9 3.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Prok-RING_4 PF14447.6 KXZ52385.1 - 1.4e-05 24.9 8.0 2.7e-05 23.9 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TPR_17 PF13431.6 KXZ52385.1 - 5.3e-05 23.3 1.7 0.16 12.4 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ52385.1 - 0.00015 21.7 3.7 1.4 9.3 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 KXZ52385.1 - 0.0014 18.9 8.7 0.0023 18.2 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain TPR_6 PF13174.6 KXZ52385.1 - 0.0054 17.3 5.2 0.02 15.5 0.6 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ52385.1 - 0.012 16.1 1.2 0.012 16.1 1.2 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 KXZ52385.1 - 0.018 15.0 8.3 0.031 14.2 8.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPR_9 PF13371.6 KXZ52385.1 - 0.055 13.6 17.0 0.17 12.1 1.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 KXZ52385.1 - 0.16 11.8 9.3 0.27 11.1 9.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fis1_TPR_C PF14853.6 KXZ52385.1 - 0.64 10.1 2.2 4.6 7.4 0.6 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat zf-C3HC4 PF00097.25 KXZ52385.1 - 0.72 9.8 8.4 1.2 9.1 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Bestrophin PF01062.21 KXZ52386.1 - 1.4e-41 142.9 0.2 1.7e-41 142.5 0.2 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DNase-RNase PF02577.14 KXZ52387.1 - 2.3e-12 46.7 0.2 0.00055 19.6 0.1 3.2 3 0 0 3 3 3 3 Bifunctional nuclease VHL PF01847.16 KXZ52387.1 - 0.0005 19.9 0.5 0.0025 17.7 0.5 1.9 1 1 0 1 1 1 1 VHL beta domain Pkinase PF00069.25 KXZ52388.1 - 9.6e-60 202.2 0.0 1.1e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52388.1 - 6.2e-18 65.0 0.0 8.5e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ52388.1 - 1.5e-08 34.9 0.0 2.5e-05 24.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ52388.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KXZ52388.1 - 0.02 14.3 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXZ52388.1 - 0.025 14.1 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF693 PF05113.13 KXZ52388.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF693) FTA2 PF13095.6 KXZ52388.1 - 0.15 11.7 0.2 0.57 9.8 0.2 2.0 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2459 PF09601.10 KXZ52388.1 - 0.15 11.8 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) MMR_HSR1 PF01926.23 KXZ52390.1 - 9.8e-17 61.1 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXZ52390.1 - 3.7e-05 23.8 0.1 0.069 13.2 0.0 2.2 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KXZ52390.1 - 9.1e-05 22.4 0.2 0.056 13.4 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KXZ52390.1 - 0.00062 19.8 0.0 0.0009 19.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KXZ52390.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF1949 PF09186.11 KXZ52390.1 - 0.0021 17.9 1.1 0.18 11.7 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1949) GTP_EFTU PF00009.27 KXZ52390.1 - 0.013 15.0 0.3 0.39 10.2 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Bclt PF15318.6 KXZ52390.1 - 0.046 13.6 0.3 0.081 12.8 0.3 1.4 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis ArsD PF06953.11 KXZ52390.1 - 0.14 12.5 0.0 1.2 9.5 0.0 2.0 1 1 1 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD Septin PF00735.18 KXZ52390.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Septin F-box PF00646.33 KXZ52391.1 - 0.011 15.7 0.0 0.04 13.8 0.0 2.0 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXZ52391.1 - 0.02 14.8 1.4 0.022 14.6 0.0 1.8 2 0 0 2 2 2 0 F-box-like Glyco_transf_5 PF08323.11 KXZ52394.1 - 4.4e-23 82.2 1.2 1.5e-13 51.1 0.1 2.7 2 1 1 3 3 3 2 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXZ52394.1 - 3.3e-09 36.5 0.0 5.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ52394.1 - 9.9e-08 32.5 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ52394.1 - 0.02 14.9 0.1 0.36 10.8 0.1 2.6 2 1 1 3 3 3 0 Glycosyltransferase Family 4 bZIP_2 PF07716.15 KXZ52394.1 - 0.55 10.3 5.0 0.91 9.7 5.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper TruB_N PF01509.18 KXZ52395.1 - 1.1e-09 38.8 0.0 1.7e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXZ52395.1 - 0.011 15.8 0.1 0.024 14.8 0.1 1.5 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain DEAD PF00270.29 KXZ52396.1 - 1e-84 282.7 0.0 3.5e-43 147.4 0.0 4.3 5 0 0 5 5 5 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ52396.1 - 3.6e-45 152.9 0.9 7.8e-21 74.5 0.0 4.8 5 0 0 5 5 5 2 Helicase conserved C-terminal domain Transcrip_act PF04949.13 KXZ52397.1 - 3.3e-07 30.3 8.9 3.3e-07 30.3 8.9 1.9 2 0 0 2 2 2 1 Transcriptional activator Spc7 PF08317.11 KXZ52397.1 - 0.0068 15.3 12.4 0.0068 15.3 12.4 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF3896 PF13035.6 KXZ52397.1 - 2 8.6 4.9 2.2 8.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TFIIA PF03153.13 KXZ52397.1 - 7.8 6.4 20.2 9.7 6.1 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KXZ52398.1 - 2.2e-63 214.1 0.0 1.3e-62 211.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KXZ52398.1 - 1.3e-40 137.4 1.6 2.5e-19 69.1 0.1 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KXZ52398.1 - 3.2e-27 95.5 0.0 7.2e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ52398.1 - 0.0016 17.8 0.0 0.013 14.9 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KXZ52398.1 - 0.0016 18.4 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2459 PF09601.10 KXZ52398.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) Ntox1 PF15500.6 KXZ52398.1 - 0.15 12.4 0.3 0.39 11.1 0.3 1.7 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Chlorophyllase2 PF12740.7 KXZ52399.1 - 8.3e-08 31.4 0.0 1.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 KXZ52399.1 - 2e-05 24.5 0.5 2.9e-05 24.0 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KXZ52399.1 - 3.1e-05 23.2 0.0 4.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 KXZ52399.1 - 0.00018 20.9 1.4 0.00098 18.5 1.4 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ52399.1 - 0.0012 19.5 11.2 0.002 18.8 11.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXZ52399.1 - 0.023 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 KXZ52399.1 - 0.031 13.8 0.0 6.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family SMP PF04927.12 KXZ52399.1 - 0.11 12.9 1.3 0.28 11.7 1.3 1.7 1 0 0 1 1 1 0 Seed maturation protein AAA_2 PF07724.14 KXZ52400.1 - 1.4e-42 145.7 0.0 3.9e-42 144.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KXZ52400.1 - 9.4e-15 55.2 0.1 3.7e-14 53.3 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXZ52400.1 - 8.7e-09 35.3 0.0 2.5e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXZ52400.1 - 8.7e-06 25.8 0.1 3.6e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXZ52400.1 - 1.1e-05 25.0 0.2 0.0021 17.5 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KXZ52400.1 - 0.00012 22.3 0.3 0.0018 18.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KXZ52400.1 - 0.00016 21.4 0.0 0.027 14.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 KXZ52400.1 - 0.00048 19.9 0.2 0.0018 18.1 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KXZ52400.1 - 0.00084 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KXZ52400.1 - 0.0012 19.3 0.7 0.0048 17.3 0.1 2.1 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 KXZ52400.1 - 0.0016 18.6 0.0 0.0043 17.2 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain T2SSE PF00437.20 KXZ52400.1 - 0.0037 16.4 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KXZ52400.1 - 0.0057 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KXZ52400.1 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MCM PF00493.23 KXZ52400.1 - 0.007 15.5 0.3 0.015 14.4 0.1 1.6 2 0 0 2 2 2 1 MCM P-loop domain ABC_tran PF00005.27 KXZ52400.1 - 0.01 16.4 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXZ52400.1 - 0.057 14.0 0.1 0.19 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXZ52400.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KXZ52400.1 - 0.076 12.9 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_29 PF13555.6 KXZ52400.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KXZ52400.1 - 0.11 12.0 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein DEAD PF00270.29 KXZ52400.1 - 0.11 12.2 0.8 0.73 9.6 0.8 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KXZ52400.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXZ52400.1 - 0.12 12.7 0.3 1.6 9.0 0.1 2.5 2 1 1 3 3 2 0 AAA domain NB-ARC PF00931.22 KXZ52400.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KXZ52400.1 - 0.14 12.5 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF4097 PF13349.6 KXZ52401.1 - 0.092 12.1 0.3 0.17 11.2 0.3 1.3 1 0 0 1 1 1 0 Putative adhesin TPT PF03151.16 KXZ52402.1 - 2.7e-98 328.9 16.9 3e-98 328.8 16.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ52402.1 - 1.4e-06 28.5 26.1 0.00023 21.3 13.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KXZ52402.1 - 0.00063 19.0 0.7 0.0015 17.8 0.3 1.8 1 1 1 2 2 2 1 Nucleotide-sugar transporter DUF676 PF05057.14 KXZ52402.1 - 0.0041 16.7 1.0 0.84 9.1 0.1 2.5 3 0 0 3 3 3 2 Putative serine esterase (DUF676) UAA PF08449.11 KXZ52402.1 - 0.073 12.3 10.5 0.16 11.1 10.5 1.7 1 1 0 1 1 1 0 UAA transporter family Glyco_transf_5 PF08323.11 KXZ52403.1 - 9.9e-63 212.1 0.2 1.1e-61 208.7 0.1 2.1 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXZ52403.1 - 8.4e-12 45.0 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXZ52403.1 - 3.9e-09 37.1 8.2 1.5e-08 35.2 0.8 3.9 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain CBM53 PF16760.5 KXZ52403.1 - 4.6e-09 36.7 0.1 1.6e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) Glyco_transf_4 PF13439.6 KXZ52403.1 - 4.6e-08 33.3 6.1 7.4e-07 29.3 1.9 4.0 3 1 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXZ52403.1 - 1.6e-07 31.8 0.0 4.3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 HTH_23 PF13384.6 KXZ52404.1 - 0.09 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Coat_F PF07875.12 KXZ52404.1 - 0.11 12.7 0.1 0.72 10.1 0.0 2.2 2 1 1 3 3 3 0 Coat F domain DUF3144 PF11342.8 KXZ52404.1 - 1.9 8.9 3.8 2.8 8.3 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3144) Porphobil_deam PF01379.20 KXZ52405.1 - 4.7e-78 261.4 0.0 6.6e-78 260.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KXZ52405.1 - 5.7e-15 55.5 0.0 1.4e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain FA_hydroxylase PF04116.13 KXZ52406.1 - 1.2e-16 61.3 23.8 1.2e-16 61.3 23.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SET PF00856.28 KXZ52407.1 - 0.0002 21.8 0.0 0.002 18.5 0.0 2.3 2 0 0 2 2 2 1 SET domain VASt PF16016.5 KXZ52408.1 - 1.3e-30 106.9 0.0 1.7e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXZ52408.1 - 4.3e-12 45.9 0.1 8.3e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 GRAM domain VWA_2 PF13519.6 KXZ52409.1 - 1.4e-19 70.7 0.0 6.5e-19 68.6 0.0 2.1 1 1 1 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 KXZ52409.1 - 7.6e-08 31.7 24.4 0.006 16.4 6.8 3.7 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 KXZ52409.1 - 2.9e-05 24.0 0.1 6.1e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Ssl1-like Cas_DxTHG PF09455.10 KXZ52409.1 - 0.15 11.6 0.5 0.21 11.1 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family MFS_1 PF07690.16 KXZ52410.1 - 4.3e-51 173.9 31.2 4.3e-51 173.9 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KXZ52410.1 - 0.37 9.0 14.4 0.023 13.0 1.3 2.4 2 1 0 2 2 2 0 BT1 family TRAPP PF04051.16 KXZ52411.1 - 9.3e-40 135.7 0.0 1.1e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Abhydrolase_6 PF12697.7 KXZ52412.1 - 9.3e-11 42.7 0.3 9.3e-11 42.7 0.3 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Cornifin PF02389.15 KXZ52412.1 - 4.5e-05 23.6 14.9 4.5e-05 23.6 14.9 1.9 1 1 0 1 1 1 1 Cornifin (SPRR) family Hydrolase_4 PF12146.8 KXZ52412.1 - 0.0026 17.1 0.0 0.0091 15.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DNA_pol_A PF00476.20 KXZ52413.1 - 2.2e-107 359.4 0.0 3.4e-107 358.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DEAD PF00270.29 KXZ52413.1 - 2e-13 50.5 0.0 3.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ52413.1 - 6.3e-10 39.4 0.0 5.1e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ52413.1 - 0.031 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PALP PF00291.25 KXZ52414.1 - 1.4e-29 103.4 0.1 1.6e-29 103.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FBD PF08387.10 KXZ52414.1 - 0.074 13.0 0.0 8.6 6.3 0.0 2.5 2 0 0 2 2 2 0 FBD GHMP_kinases_C PF08544.13 KXZ52414.1 - 0.12 12.7 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal ENTH PF01417.20 KXZ52415.1 - 5e-35 120.3 0.0 6.6e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KXZ52415.1 - 7.5e-05 21.9 0.0 9.9e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 ANTH domain Arf PF00025.21 KXZ52416.1 - 1.4e-51 174.4 0.0 1.5e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXZ52416.1 - 4.8e-11 42.9 0.0 6.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXZ52416.1 - 9.5e-10 38.2 0.2 6.2e-06 25.6 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXZ52416.1 - 2e-09 37.1 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXZ52416.1 - 3.2e-09 36.6 0.0 3.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KXZ52416.1 - 5.8e-08 32.8 0.0 7.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXZ52416.1 - 4.1e-06 26.3 0.0 4.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXZ52416.1 - 6.4e-06 25.8 0.0 0.0031 17.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KXZ52416.1 - 0.0069 16.9 0.0 0.009 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ52416.1 - 0.012 15.9 0.0 0.053 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KXZ52416.1 - 0.016 15.1 0.1 0.063 13.2 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TniB PF05621.11 KXZ52416.1 - 0.022 14.2 0.1 0.077 12.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Dynamin_N PF00350.23 KXZ52416.1 - 0.061 13.4 0.0 6.5 6.8 0.0 2.1 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.18 KXZ52416.1 - 0.079 12.5 0.2 0.19 11.2 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B SHMT PF00464.19 KXZ52417.1 - 3.8e-205 681.0 0.0 4.5e-205 680.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KXZ52417.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.25 KXZ52418.1 - 2.5e-14 53.3 0.2 9.4e-10 38.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52418.1 - 3.2e-10 39.7 0.1 7.8e-08 31.9 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ52418.1 - 0.0055 16.7 0.0 0.0061 16.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ52419.1 - 5.5e-23 81.7 0.0 2.4e-13 50.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52419.1 - 1.3e-22 80.3 0.0 9.1e-20 71.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ52419.1 - 0.0028 17.6 0.5 0.0072 16.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2173 PF09941.9 KXZ52419.1 - 0.15 12.4 0.3 3.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2173) GRIM-19 PF06212.12 KXZ52420.1 - 2e-31 108.7 0.0 2.4e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein SURF1 PF02104.15 KXZ52421.1 - 1e-35 123.5 0.0 4.2e-35 121.6 0.0 1.8 1 1 0 1 1 1 1 SURF1 family DUF4604 PF15377.6 KXZ52421.1 - 0.89 10.0 5.9 0.27 11.7 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Arm PF00514.23 KXZ52422.1 - 3.1e-10 39.7 41.6 0.00063 19.7 0.4 10.8 10 1 1 11 11 11 6 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KXZ52422.1 - 1.9e-07 31.3 0.1 12 5.9 0.0 5.3 5 0 0 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXZ52422.1 - 2.5e-05 24.6 54.3 0.31 11.4 3.1 8.0 4 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KXZ52422.1 - 3.5e-05 23.7 33.9 0.097 13.0 0.8 9.5 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 KXZ52422.1 - 0.02 15.4 56.3 0.022 15.3 0.2 8.0 7 2 1 8 8 8 0 HEAT-like repeat RIX1 PF08167.12 KXZ52422.1 - 0.026 14.3 2.4 3.2 7.4 0.2 3.3 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis V-ATPase_H_N PF03224.14 KXZ52422.1 - 0.029 13.6 0.0 0.089 12.1 0.0 1.7 2 0 0 2 2 2 0 V-ATPase subunit H Creb_binding PF09030.10 KXZ52422.1 - 5.1 7.8 6.0 45 4.8 0.0 3.6 4 0 0 4 4 4 0 Creb binding VOMI PF03762.17 KXZ52423.1 - 1.5e-33 116.4 4.9 1.5e-33 116.3 0.3 2.6 3 0 0 3 3 3 1 Vitelline membrane outer layer protein I (VOMI) Ricin_B_lectin PF00652.22 KXZ52423.1 - 5.3e-19 68.7 0.1 1e-09 38.7 0.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXZ52423.1 - 2.1e-18 66.8 2.1 3.7e-09 37.2 0.5 3.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KXZ52423.1 - 1.5e-05 24.7 2.2 2e-05 24.2 0.2 2.1 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain EF-hand_1 PF00036.32 KXZ52423.1 - 0.00015 21.1 0.0 0.00031 20.1 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ52423.1 - 0.0056 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXZ52423.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KXZ52423.1 - 0.027 14.9 0.1 0.05 14.0 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair PARM PF17061.5 KXZ52423.1 - 1.1 9.4 9.3 0.04 14.0 1.5 2.3 2 1 0 2 2 2 0 PARM DUF3348 PF11828.8 KXZ52425.1 - 9e-05 22.3 3.9 9e-05 22.3 3.9 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3348) HEAT PF02985.22 KXZ52425.1 - 0.13 12.5 0.2 0.13 12.5 0.2 3.0 3 0 0 3 3 3 0 HEAT repeat Dynamin_N PF00350.23 KXZ52426.1 - 7.3e-14 52.2 0.2 6e-13 49.2 0.0 2.5 2 1 0 2 2 1 1 Dynamin family MMR_HSR1 PF01926.23 KXZ52426.1 - 7.7e-06 26.0 0.0 0.00013 22.0 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXZ52426.1 - 0.00013 22.5 0.0 0.0003 21.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF3348 PF11828.8 KXZ52426.1 - 0.00014 21.6 4.2 0.00014 21.6 4.2 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3348) RsgA_GTPase PF03193.16 KXZ52426.1 - 0.00016 21.6 0.0 0.00073 19.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase preATP-grasp_3 PF18301.1 KXZ52426.1 - 0.052 13.8 0.0 0.25 11.7 0.0 2.2 1 0 0 1 1 1 0 pre ATP-grasp 3 domain SDA1 PF05285.12 KXZ52426.1 - 0.078 12.4 15.3 0.15 11.5 15.3 1.5 1 0 0 1 1 1 0 SDA1 FeoB_N PF02421.18 KXZ52426.1 - 0.11 12.1 0.0 16 5.0 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B HEAT PF02985.22 KXZ52426.1 - 0.12 12.6 0.1 0.81 10.1 0.1 2.5 1 0 0 1 1 1 0 HEAT repeat Nop14 PF04147.12 KXZ52426.1 - 0.14 10.3 16.0 0.21 9.8 16.0 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_29 PF13555.6 KXZ52426.1 - 0.17 11.7 0.1 0.53 10.1 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDC45 PF02724.14 KXZ52426.1 - 0.19 10.0 15.2 0.31 9.3 15.2 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_16 PF13191.6 KXZ52426.1 - 0.2 12.0 0.0 0.2 12.0 0.0 4.8 2 1 0 2 2 1 0 AAA ATPase domain Adeno_IVa2 PF02456.15 KXZ52426.1 - 0.25 10.1 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein IIGP PF05049.13 KXZ52426.1 - 0.32 10.0 0.0 0.56 9.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Paf1 PF03985.13 KXZ52426.1 - 6.1 5.7 13.5 10 5.0 13.5 1.3 1 0 0 1 1 1 0 Paf1 SnoaL PF07366.12 KXZ52427.1 - 7.3e-07 29.0 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXZ52427.1 - 6.3e-06 26.8 0.0 0.00028 21.5 0.0 2.2 1 1 0 1 1 1 1 SnoaL-like domain LSM PF01423.22 KXZ52428.1 - 2.6e-19 68.7 0.1 3.4e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KXZ52428.1 - 0.0034 17.5 0.5 0.0073 16.4 0.5 1.5 1 1 0 1 1 1 1 RimP C-terminal SH3 domain vATP-synt_E PF01991.18 KXZ52428.1 - 0.027 13.9 0.1 0.037 13.4 0.1 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Guanylate_cyc PF00211.20 KXZ52429.1 - 4.2e-55 186.2 0.0 6.2e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CYTH PF01928.21 KXZ52430.1 - 1.2e-25 90.5 0.1 1.4e-25 90.3 0.1 1.0 1 0 0 1 1 1 1 CYTH domain CCB1 PF12046.8 KXZ52431.1 - 6.3e-51 172.0 0.0 7.5e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B Cna_B PF05738.13 KXZ52431.1 - 0.085 13.4 0.8 2.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Cna protein B-type domain KH_1 PF00013.29 KXZ52432.1 - 4.9e-07 29.5 0.5 4.4e-06 26.4 0.5 2.1 1 1 0 1 1 1 1 KH domain Peptidase_C97 PF05903.14 KXZ52433.1 - 2.3e-22 79.5 0.0 3.3e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXZ52433.1 - 0.1 12.9 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Pkinase_Tyr PF07714.17 KXZ52434.1 - 7.8e-20 71.2 0.0 7.8e-09 35.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ52434.1 - 5.2e-19 68.6 0.0 9.1e-10 38.3 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Kdo PF06293.14 KXZ52434.1 - 0.046 13.1 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rad60-SLD PF11976.8 KXZ52435.1 - 4.5e-15 55.2 0.0 5.4e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXZ52435.1 - 9e-10 38.2 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Glyco_transf_20 PF00982.21 KXZ52436.1 - 4.2e-135 451.1 0.0 9.3e-135 449.9 0.0 1.5 1 1 1 2 2 2 1 Glycosyltransferase family 20 Bestrophin PF01062.21 KXZ52436.1 - 2.9e-40 138.5 0.4 4.1e-40 138.0 0.4 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Trehalose_PPase PF02358.16 KXZ52436.1 - 1.8e-17 63.2 0.0 8.7e-16 57.7 0.0 2.4 2 0 0 2 2 2 1 Trehalose-phosphatase Pkinase_Tyr PF07714.17 KXZ52437.1 - 1.8e-21 76.6 0.0 1e-08 34.8 0.0 4.2 4 0 0 4 4 4 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ52437.1 - 6.9e-21 74.8 0.0 3.9e-09 36.3 0.0 4.4 4 1 0 4 4 4 4 Protein kinase domain Kdo PF06293.14 KXZ52437.1 - 0.042 13.2 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C97 PF05903.14 KXZ52439.1 - 1.9e-22 79.7 0.0 3e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXZ52439.1 - 0.083 13.2 0.1 0.14 12.5 0.1 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase SET PF00856.28 KXZ52440.1 - 2.7e-09 37.6 0.1 8e-09 36.1 0.0 1.8 2 1 0 2 2 2 1 SET domain PGA2 PF07543.12 KXZ52440.1 - 8.5 6.4 6.6 0.77 9.7 1.1 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 Vint PF14623.6 KXZ52442.1 - 1.6e-06 28.0 0.0 5.8e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Hint-domain Hint_2 PF13403.6 KXZ52442.1 - 0.00019 21.7 0.6 0.0041 17.4 0.2 2.4 2 0 0 2 2 2 1 Hint domain Vint PF14623.6 KXZ52443.1 - 6.3e-06 26.1 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Hint-domain Hint_2 PF13403.6 KXZ52443.1 - 0.1 12.9 0.2 0.59 10.4 0.1 2.1 1 1 1 2 2 2 0 Hint domain RRM_1 PF00076.22 KXZ52444.1 - 1.9e-41 139.7 0.1 8.7e-14 51.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ52444.1 - 2e-13 50.3 0.1 0.00013 22.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 KXZ52444.1 - 1.3e-07 31.5 0.1 0.69 10.0 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KXZ52444.1 - 0.012 15.9 0.0 33 4.7 0.0 3.9 2 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Bac_globin PF01152.21 KXZ52445.1 - 4e-09 36.6 0.0 9.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial-like globin Acetyltransf_1 PF00583.25 KXZ52446.1 - 4.8e-10 39.7 0.0 7.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ52446.1 - 3.9e-08 33.6 0.0 6.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ52446.1 - 2.3e-07 30.8 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ52446.1 - 5.9e-05 23.0 0.0 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KXZ52446.1 - 0.0001 22.4 0.1 0.00044 20.3 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXZ52446.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ank_2 PF12796.7 KXZ52447.1 - 0.012 16.1 1.0 0.065 13.8 0.3 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ52447.1 - 0.028 14.9 0.4 0.028 14.9 0.4 2.8 3 0 0 3 3 3 0 Ankyrin repeat CAP59_mtransfer PF11735.8 KXZ52448.1 - 2.9e-60 203.9 0.0 4.3e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Rad60-SLD PF11976.8 KXZ52449.1 - 2.5e-07 30.4 0.1 2.8e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXZ52449.1 - 0.0022 17.7 0.0 0.0022 17.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family SPC12 PF06645.13 KXZ52451.1 - 2.4e-27 94.8 0.4 2.7e-27 94.6 0.4 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) IF-2B PF01008.17 KXZ52452.1 - 1e-64 218.5 0.0 1.6e-64 217.8 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family WD40 PF00400.32 KXZ52453.1 - 4.1e-39 131.8 10.1 2.7e-06 28.0 0.1 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ52453.1 - 5.5e-14 52.2 0.0 0.039 14.2 0.0 6.4 3 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KXZ52453.1 - 5.8e-12 44.9 11.2 1.9e-11 43.3 8.2 2.6 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 KXZ52453.1 - 0.00032 19.8 1.0 0.19 10.7 0.0 4.5 1 1 5 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXZ52453.1 - 0.0027 17.1 0.0 0.02 14.2 0.0 2.3 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KXZ52453.1 - 0.0072 15.0 0.2 4.3 5.8 0.0 3.1 4 0 0 4 4 4 2 Nucleoporin Nup120/160 GBP PF02263.19 KXZ52454.1 - 3.7e-29 101.8 0.0 8.4e-27 94.1 0.0 2.0 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KXZ52454.1 - 0.34 9.0 0.0 0.49 8.5 0.0 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Glycos_transf_4 PF00953.21 KXZ52455.1 - 1.4e-36 125.9 15.0 2.9e-36 124.9 15.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 DUF3456 PF11938.8 KXZ52459.1 - 6.3e-12 46.3 0.0 1e-11 45.6 0.0 1.2 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP FAST_1 PF06743.15 KXZ52459.1 - 5.9e-07 29.4 0.3 4.1 7.4 0.0 5.4 4 2 1 5 5 5 3 FAST kinase-like protein, subdomain 1 DUF1601 PF07671.11 KXZ52459.1 - 0.0086 15.9 0.1 0.14 12.1 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1601) AP2 PF00847.20 KXZ52460.1 - 0.00014 22.0 0.3 0.00014 22.0 0.3 2.2 2 0 0 2 2 2 1 AP2 domain NT5C PF06941.12 KXZ52461.1 - 1.5e-08 34.7 0.0 3.6e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 KXZ52461.1 - 2.9e-05 24.2 0.0 4.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 KXZ52461.1 - 0.00015 21.5 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 KXZ52461.1 - 0.046 13.8 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2509 PF10713.9 KXZ52461.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) Hydrolase PF00702.26 KXZ52461.1 - 0.22 11.8 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fascin PF06268.13 KXZ52462.1 - 0.00022 21.4 0.0 0.0005 20.3 0.0 1.6 1 0 0 1 1 1 1 Fascin domain FRG1 PF06229.12 KXZ52462.1 - 0.0029 17.3 0.0 0.0095 15.7 0.0 1.9 1 1 0 1 1 1 1 FRG1-like domain DUF569 PF04601.13 KXZ52462.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF569) TPR_2 PF07719.17 KXZ52464.1 - 1.8 8.9 7.0 57 4.2 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ52464.1 - 5.7 7.8 12.3 3.4 8.5 0.2 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Histone PF00125.24 KXZ52465.1 - 3.9e-43 147.0 0.4 4.2e-43 146.8 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ52465.1 - 0.00014 22.2 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ52465.1 - 0.00032 20.8 0.0 0.00042 20.4 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ52465.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2922 PF11148.8 KXZ52469.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) HTH_Crp_2 PF13545.6 KXZ52469.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Bac_globin PF01152.21 KXZ52470.1 - 0.00078 19.6 0.0 0.11 12.7 0.0 2.5 1 1 1 2 2 2 2 Bacterial-like globin Bac_globin PF01152.21 KXZ52471.1 - 1e-10 41.8 0.1 1.9e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial-like globin FMO-like PF00743.19 KXZ52472.1 - 1.2e-05 23.9 0.0 1.1 7.6 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXZ52472.1 - 0.00021 20.5 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXZ52472.1 - 0.0014 18.0 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ52472.1 - 0.031 13.5 1.0 0.24 10.6 1.5 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4033 PF13225.6 KXZ52473.1 - 9.7e-40 134.5 0.5 2.8e-39 133.0 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4033) Bac_globin PF01152.21 KXZ52474.1 - 1.4e-06 28.5 0.0 3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial-like globin Presenilin PF01080.17 KXZ52474.1 - 0.041 12.7 10.0 0.054 12.3 10.0 1.1 1 0 0 1 1 1 0 Presenilin MAJIN PF15077.6 KXZ52474.1 - 0.068 13.0 6.9 0.11 12.3 6.9 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein GREB1 PF15782.5 KXZ52474.1 - 0.48 7.5 3.7 0.55 7.3 3.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 KXZ52474.1 - 1.2 8.1 13.8 2.1 7.3 13.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein SLC12 PF03522.15 KXZ52474.1 - 1.4 7.9 7.0 2.1 7.3 7.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AAA_11 PF13086.6 KXZ52474.1 - 1.8 8.3 8.6 2.8 7.6 8.6 1.3 1 0 0 1 1 1 0 AAA domain ALMT PF11744.8 KXZ52474.1 - 2.5 6.9 5.8 3.2 6.5 5.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MCM_bind PF09739.9 KXZ52474.1 - 2.9 6.2 10.4 3.8 5.9 10.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4569 PF15133.6 KXZ52474.1 - 3 7.5 7.7 4.4 6.9 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CDC45 PF02724.14 KXZ52474.1 - 8.7 4.5 14.3 12 4.0 14.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Rubis-subs-bind PF09273.11 KXZ52475.1 - 6e-26 91.7 0.1 2.1e-25 89.9 0.0 1.9 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 KXZ52475.1 - 7.5e-07 29.7 0.0 2.2e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KXZ52475.1 - 0.022 15.4 0.4 6.8 7.4 0.1 2.7 2 0 0 2 2 2 0 SAF domain Ribosomal_L34e PF01199.18 KXZ52476.1 - 4.8e-37 126.2 2.4 7.5e-37 125.5 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Pkinase PF00069.25 KXZ52477.1 - 4.9e-73 245.7 0.0 6.1e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52477.1 - 2.1e-32 112.5 0.1 1.4e-31 109.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DAPG_hydrolase PF18089.1 KXZ52477.1 - 5.3e-05 22.9 0.4 0.074 12.6 0.0 2.2 2 0 0 2 2 2 2 DAPG hydrolase PhiG domain AAA_19 PF13245.6 KXZ52478.1 - 6.7e-09 36.2 0.0 2.2e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXZ52478.1 - 6.7e-05 22.6 0.1 0.00079 19.2 0.1 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXZ52478.1 - 0.00012 21.7 2.0 0.00068 19.2 2.0 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 KXZ52478.1 - 0.0068 16.1 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXZ52478.1 - 0.048 13.9 0.0 0.83 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 KXZ52478.1 - 0.053 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXZ52479.1 - 2.1e-07 31.4 0.0 7.5e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXZ52479.1 - 2.7e-06 27.1 0.4 2.5e-05 24.0 0.4 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXZ52479.1 - 3.5e-05 23.5 0.1 7.8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KXZ52479.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXZ52479.1 - 0.0067 16.2 0.0 2 8.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain Metallophos PF00149.28 KXZ52480.1 - 5.2e-10 40.2 0.1 7.9e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ52480.1 - 0.002 18.4 0.0 0.0094 16.2 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 KXZ52480.1 - 0.024 13.7 0.0 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 PhoD-like phosphatase FhuF_C PF11575.8 KXZ52480.1 - 0.16 11.9 2.4 0.84 9.6 2.4 2.3 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain RRM_1 PF00076.22 KXZ52481.1 - 6.2e-15 54.8 0.1 2.8e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.31 KXZ52482.1 - 2.7e-18 66.3 0.0 1e-16 61.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ52482.1 - 1.6e-17 63.9 0.0 3.4e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 KXZ52482.1 - 0.029 13.2 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Med26 PF08711.11 KXZ52482.1 - 0.036 14.1 0.1 0.088 12.8 0.1 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain ResIII PF04851.15 KXZ52482.1 - 0.21 11.6 0.0 0.62 10.1 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase_Tyr PF07714.17 KXZ52483.1 - 1.9e-76 256.8 0.0 2.4e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ52483.1 - 4e-62 210.0 0.0 5.5e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ52483.1 - 4.1e-05 22.5 0.1 9.1e-05 21.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase ACT PF01842.25 KXZ52483.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain APH PF01636.23 KXZ52483.1 - 0.00011 22.2 0.3 0.036 14.0 0.2 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ52483.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXZ52483.1 - 0.022 14.1 0.2 0.049 13.0 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXZ52483.1 - 0.047 12.6 0.1 0.095 11.6 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Cyt-b5 PF00173.28 KXZ52484.1 - 2.2e-24 85.4 0.1 2.8e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.22 KXZ52485.1 - 1.3e-43 149.5 0.0 1.6e-26 93.1 0.0 3.7 3 1 0 3 3 3 3 Cytochrome P450 RRM_1 PF00076.22 KXZ52486.1 - 7.1e-10 38.6 0.0 0.0069 16.2 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ52486.1 - 0.11 12.6 0.0 17 5.6 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif zf-MYND PF01753.18 KXZ52488.1 - 9.6e-07 28.8 8.4 2.5e-06 27.5 8.4 1.7 1 0 0 1 1 1 1 MYND finger PmbA_TldD PF01523.16 KXZ52488.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Sulfotransfer_3 PF13469.6 KXZ52490.1 - 0.00027 21.4 0.0 0.00072 20.0 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 KXZ52490.1 - 0.035 14.0 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Sulfotransferase domain Chorismate_bind PF00425.18 KXZ52491.1 - 4.4e-50 170.7 0.0 3.1e-44 151.5 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme TPP_enzyme_N PF02776.18 KXZ52491.1 - 3.7e-33 114.6 0.1 3.7e-33 114.6 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 KXZ52491.1 - 3.4e-08 33.4 0.1 2e-06 27.7 0.1 3.0 3 1 0 3 3 3 1 Middle domain of thiamine pyrophosphate MR_MLE_C PF13378.6 KXZ52492.1 - 4.4e-24 85.3 9.0 4.4e-24 85.3 9.0 2.6 2 1 0 2 2 2 1 Enolase C-terminal domain-like Abhydrolase_1 PF00561.20 KXZ52492.1 - 9.1e-14 51.7 0.0 4.1e-13 49.6 0.0 2.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ52492.1 - 8.4e-05 23.3 57.8 8.4e-05 23.3 57.8 4.5 2 2 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ52492.1 - 0.0032 16.8 0.3 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF726 PF05277.12 KXZ52492.1 - 0.056 12.4 0.2 0.056 12.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF726) Abhydro_lipase PF04083.16 KXZ52492.1 - 0.21 11.2 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region KH_dom-like PF14714.6 KXZ52493.1 - 2.9e-30 104.4 0.0 4.4e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal MMR_HSR1 PF01926.23 KXZ52493.1 - 3.9e-20 72.0 0.0 6.7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXZ52493.1 - 1.5e-08 34.4 0.1 3.9e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXZ52493.1 - 2.6e-06 27.6 0.1 0.01 15.9 0.0 2.2 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 KXZ52493.1 - 2.2e-05 24.1 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Glyco_hydro_3_C PF01915.22 KXZ52493.1 - 0.022 14.7 0.3 0.033 14.1 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain RsgA_GTPase PF03193.16 KXZ52493.1 - 0.054 13.4 0.2 0.2 11.5 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 KXZ52493.1 - 0.059 12.7 0.2 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 AIG1 family TK PF00265.18 KXZ52493.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase ABC_tran PF00005.27 KXZ52494.1 - 4.7e-29 101.6 0.0 3.9e-26 92.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 KXZ52494.1 - 3.2e-24 85.2 1.1 1.1e-20 73.9 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ52494.1 - 4.9e-08 32.6 0.0 1.8e-07 30.8 0.0 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KXZ52494.1 - 7.8e-06 26.4 0.6 0.019 15.3 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KXZ52494.1 - 2.9e-05 24.0 0.0 0.44 10.3 0.2 2.8 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ52494.1 - 3.7e-05 23.4 0.2 0.044 13.5 0.1 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXZ52494.1 - 8.1e-05 22.9 0.0 0.15 12.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain GTP_EFTU PF00009.27 KXZ52494.1 - 0.00036 20.1 0.0 0.057 12.9 0.0 3.7 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KXZ52494.1 - 0.00094 18.6 0.4 0.0064 15.8 0.0 2.3 3 0 0 3 3 3 1 AIG1 family RsgA_GTPase PF03193.16 KXZ52494.1 - 0.0017 18.3 0.0 7.2 6.5 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 KXZ52494.1 - 0.014 15.6 0.0 0.73 10.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXZ52494.1 - 0.029 14.1 0.1 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXZ52494.1 - 0.043 14.0 0.5 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KXZ52494.1 - 0.05 12.9 0.1 0.65 9.2 0.1 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.6 KXZ52494.1 - 0.054 14.0 0.5 3.4 8.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 KXZ52494.1 - 0.063 12.6 0.0 3.5 6.9 0.1 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.29 KXZ52494.1 - 0.068 13.6 0.0 20 5.6 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXZ52494.1 - 0.12 12.5 0.0 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXZ52494.1 - 0.15 11.9 0.5 19 5.1 0.0 2.7 3 0 0 3 3 2 0 NTPase RNA_helicase PF00910.22 KXZ52494.1 - 0.17 12.3 0.0 19 5.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 KXZ52494.1 - 0.39 10.8 1.1 1 9.4 0.0 2.2 2 1 0 2 2 2 0 Dynamin family Spindle_Spc25 PF08234.12 KXZ52495.1 - 4.1e-18 65.4 0.1 1.6e-16 60.3 0.0 2.5 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4775 PF16001.5 KXZ52495.1 - 0.0056 16.2 5.1 0.0059 16.1 5.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4775) TPR_MLP1_2 PF07926.12 KXZ52495.1 - 0.012 15.7 25.6 0.022 14.8 25.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein dCache_3 PF14827.6 KXZ52495.1 - 0.012 15.2 1.7 0.018 14.7 1.7 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Exonuc_VII_L PF02601.15 KXZ52495.1 - 0.014 15.0 9.4 0.016 14.8 9.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 KXZ52495.1 - 0.029 13.2 15.4 0.052 12.4 15.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KXZ52495.1 - 0.12 11.8 9.4 0.14 11.5 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KXZ52495.1 - 0.12 11.6 7.9 0.16 11.2 7.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein Prominin PF05478.11 KXZ52495.1 - 0.14 10.1 5.2 0.16 9.9 4.6 1.3 2 0 0 2 2 2 0 Prominin FliJ PF02050.16 KXZ52495.1 - 0.2 11.9 25.3 0.38 11.0 25.3 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein Uso1_p115_C PF04871.13 KXZ52495.1 - 0.24 11.8 21.1 0.61 10.5 16.3 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 KXZ52495.1 - 0.25 10.4 14.4 0.32 10.1 14.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-K PF11802.8 KXZ52495.1 - 0.29 10.7 12.3 0.17 11.4 10.9 1.4 2 0 0 2 2 1 0 Centromere-associated protein K DUF1818 PF08848.11 KXZ52495.1 - 0.44 10.6 5.7 0.53 10.4 4.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1818) Allexi_40kDa PF05549.11 KXZ52495.1 - 0.46 9.9 6.7 0.57 9.7 6.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF5345 PF17280.2 KXZ52495.1 - 0.59 10.2 9.0 4.7 7.3 0.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) UPF0242 PF06785.11 KXZ52495.1 - 0.73 9.9 12.7 1.1 9.4 12.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DDHD PF02862.17 KXZ52495.1 - 0.74 9.9 3.8 0.81 9.8 3.8 1.1 1 0 0 1 1 1 0 DDHD domain FAM76 PF16046.5 KXZ52495.1 - 1 8.6 10.6 1.4 8.2 10.6 1.2 1 0 0 1 1 1 0 FAM76 protein V_ATPase_I PF01496.19 KXZ52495.1 - 1.4 6.8 8.5 1.3 6.9 8.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3138 PF11336.8 KXZ52495.1 - 2.1 6.8 7.0 2.9 6.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Neur_chan_memb PF02932.16 KXZ52495.1 - 2.4 8.2 5.6 2.8 7.9 5.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Holin_BhlA PF10960.8 KXZ52495.1 - 2.7 8.0 5.5 0.4 10.7 0.2 2.2 2 1 1 3 3 3 0 BhlA holin family Helo_like_N PF17111.5 KXZ52495.1 - 3.8 6.8 12.9 0.93 8.8 8.7 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Fib_alpha PF08702.10 KXZ52495.1 - 4.6 7.4 11.8 5.5 7.2 9.8 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 KXZ52495.1 - 4.8 5.7 10.1 6.7 5.2 10.0 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 KXZ52495.1 - 4.8 7.2 7.9 13 5.8 7.2 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 KXZ52495.1 - 5.6 7.6 19.0 2.4 8.8 7.8 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Presenilin PF01080.17 KXZ52495.1 - 5.6 5.6 8.9 6.1 5.5 8.9 1.1 1 0 0 1 1 1 0 Presenilin LMBR1 PF04791.16 KXZ52495.1 - 6.3 5.6 6.1 7.3 5.4 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Fzo_mitofusin PF04799.13 KXZ52495.1 - 6.9 6.2 12.2 12 5.4 11.5 1.9 2 1 0 2 2 2 0 fzo-like conserved region OmpH PF03938.14 KXZ52495.1 - 7.2 7.0 24.5 2.2 8.6 19.3 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Myosin_head PF00063.21 KXZ52496.1 - 1.8e-241 803.1 0.0 5.9e-241 801.4 0.0 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KXZ52496.1 - 1.5e-22 79.8 1.8 3e-22 78.9 0.2 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KXZ52496.1 - 1.8e-18 64.5 44.3 4.5e-05 22.9 1.1 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif Myosin_N PF02736.19 KXZ52496.1 - 2.1e-08 33.9 6.5 3.6e-08 33.1 6.5 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KXZ52496.1 - 0.067 13.6 0.1 0.067 13.6 0.1 4.7 3 2 0 3 3 2 0 AAA ATPase domain RuvA_N PF01330.21 KXZ52496.1 - 0.093 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 RuvA N terminal domain Spc7 PF08317.11 KXZ52496.1 - 0.1 11.4 33.1 0.27 10.1 23.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Hpr_kinase_C PF07475.12 KXZ52496.1 - 0.17 11.4 0.2 8.7 5.8 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Flp1_like PF16982.5 KXZ52496.1 - 0.34 10.3 0.8 0.91 9.0 0.1 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain GAS PF13851.6 KXZ52496.1 - 0.42 9.9 32.1 0.076 12.4 15.1 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 KXZ52496.1 - 0.8 9.3 36.7 5.7 6.6 2.0 3.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HAP1_N PF04849.13 KXZ52496.1 - 1.5 8.0 25.0 13 4.9 25.0 2.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Golgin_A5 PF09787.9 KXZ52496.1 - 1.8 7.9 27.2 1.1 8.6 23.3 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 AKNA PF12443.8 KXZ52496.1 - 4.4 8.0 9.1 1.9 9.2 3.2 3.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor Caudo_TAP PF02413.17 KXZ52496.1 - 4.9 7.3 9.8 0.85 9.8 4.8 2.4 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK DUF848 PF05852.11 KXZ52496.1 - 9.2 6.4 23.4 0.4 10.8 2.5 3.5 2 1 2 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) MAD PF05557.13 KXZ52497.1 - 1.6e-05 23.5 2.5 2e-05 23.2 2.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Taxilin PF09728.9 KXZ52497.1 - 0.0052 16.0 2.5 0.0071 15.6 2.5 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein ALIX_LYPXL_bnd PF13949.6 KXZ52497.1 - 0.022 14.1 4.4 0.016 14.5 2.6 1.7 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV COG5 PF10392.9 KXZ52497.1 - 0.037 14.2 1.3 0.12 12.5 1.1 1.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 GAS PF13851.6 KXZ52497.1 - 0.043 13.2 8.6 0.096 12.0 8.6 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TetR_C_34 PF17929.1 KXZ52497.1 - 0.068 13.3 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Mo25 PF08569.11 KXZ52497.1 - 0.069 12.5 0.3 0.088 12.2 0.3 1.2 1 0 0 1 1 1 0 Mo25-like Golgin_A5 PF09787.9 KXZ52497.1 - 0.083 12.3 4.9 0.14 11.6 4.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 BST2 PF16716.5 KXZ52497.1 - 0.087 13.4 11.1 2.1 9.0 2.2 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Ax_dynein_light PF10211.9 KXZ52497.1 - 0.087 12.8 4.2 0.17 11.8 3.8 1.8 2 1 0 2 2 1 0 Axonemal dynein light chain DUF641 PF04859.12 KXZ52497.1 - 0.14 12.5 4.5 0.71 10.2 0.2 2.4 3 0 0 3 3 2 0 Plant protein of unknown function (DUF641) HSBP1 PF06825.12 KXZ52497.1 - 0.17 11.7 1.5 8.1 6.4 0.0 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 CASP_C PF08172.12 KXZ52497.1 - 0.21 10.9 4.6 0.38 10.1 4.6 1.4 1 1 0 1 1 1 0 CASP C terminal Leu_zip PF15294.6 KXZ52497.1 - 0.21 11.1 5.9 0.35 10.3 5.9 1.3 1 0 0 1 1 1 0 Leucine zipper Lectin_N PF03954.14 KXZ52497.1 - 0.23 11.2 2.8 1.8 8.3 2.8 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 KXZ52497.1 - 0.44 10.6 4.4 1.9 8.5 0.2 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KXZ52497.1 - 0.56 10.0 6.4 0.34 10.7 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-H PF05837.12 KXZ52497.1 - 0.64 10.5 8.6 4 7.9 0.3 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF3138 PF11336.8 KXZ52497.1 - 0.75 8.3 8.2 0.12 11.0 4.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) HIP1_clath_bdg PF16515.5 KXZ52497.1 - 0.79 10.4 8.4 1.2 9.8 0.9 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Csm1_N PF18504.1 KXZ52497.1 - 0.88 10.0 4.7 1.8 8.9 0.6 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain Lebercilin PF15619.6 KXZ52497.1 - 1.3 8.7 14.6 0.37 10.4 0.4 2.3 2 1 1 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 KXZ52497.1 - 1.4 9.0 11.3 3.1 7.9 0.9 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 KXZ52497.1 - 1.4 9.1 5.1 5.5 7.2 0.4 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Lzipper-MIP1 PF14389.6 KXZ52497.1 - 2.2 8.6 8.2 8.3 6.8 5.7 2.5 2 1 1 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4200 PF13863.6 KXZ52497.1 - 2.4 8.6 10.8 15 6.0 4.9 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KXZ52497.1 - 2.4 7.0 8.4 5.9 5.7 8.0 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KXZ52497.1 - 4.2 7.4 8.0 24 4.9 0.5 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1192 PF06698.11 KXZ52497.1 - 5.6 7.1 10.7 13 6.0 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) DUF4404 PF14357.6 KXZ52497.1 - 6.7 7.4 10.2 8.2 7.2 2.0 3.1 2 1 1 4 4 4 0 Domain of unknown function (DUF4404) DIL PF01843.19 KXZ52498.1 - 1.4e-23 83.1 0.3 2.7e-23 82.2 0.3 1.5 1 0 0 1 1 1 1 DIL domain Flp1_like PF16982.5 KXZ52498.1 - 0.1 12.0 0.1 0.24 10.8 0.1 1.6 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Macro PF01661.21 KXZ52499.1 - 1.2e-26 93.0 0.0 2.3e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Macro domain NUDIX PF00293.28 KXZ52500.1 - 1.9e-08 34.4 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain cobW PF02492.19 KXZ52501.1 - 1.4e-34 119.2 0.0 2.2e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ52501.1 - 0.00035 20.4 0.0 0.00097 19.0 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 KXZ52501.1 - 0.04 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KXZ52501.1 - 0.069 13.5 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ52501.1 - 0.072 13.6 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXZ52501.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KXZ52501.1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KXZ52501.1 - 0.25 10.8 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KXZ52501.1 - 0.28 10.9 0.0 0.43 10.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KXZ52501.1 - 0.28 11.2 0.0 0.56 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 KXZ52502.1 - 2.4e-84 283.1 0.0 4.6e-84 282.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ52502.1 - 8.2e-30 103.7 0.0 1.1e-25 90.3 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding IFT57 PF10498.9 KXZ52502.1 - 0.013 14.5 17.7 0.026 13.5 17.7 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4763 PF15960.5 KXZ52502.1 - 0.018 14.4 20.1 0.031 13.6 20.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Bac_DnaA PF00308.18 KXZ52502.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Glyco_tran_28_C PF04101.16 KXZ52502.1 - 0.074 13.0 5.8 0.21 11.6 5.8 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain YabA PF06156.13 KXZ52502.1 - 0.17 12.5 14.7 3 8.5 1.8 4.0 2 1 2 4 4 4 0 Initiation control protein YabA zf-C4H2 PF10146.9 KXZ52502.1 - 0.23 11.7 6.3 0.12 12.7 3.9 1.9 2 0 0 2 2 1 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.9 KXZ52502.1 - 0.26 11.3 34.0 0.16 12.0 11.4 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 KXZ52502.1 - 0.28 10.9 20.3 0.38 10.5 8.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) MapZ_EC1 PF18041.1 KXZ52502.1 - 0.56 10.4 5.0 1.3 9.2 0.2 2.4 2 0 0 2 2 2 0 MapZ extracellular domain 1 Spc7 PF08317.11 KXZ52502.1 - 1 8.1 30.4 0.46 9.3 12.3 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 KXZ52502.1 - 1.5 6.2 28.2 2.2 5.7 28.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.13 KXZ52502.1 - 2.3 6.5 29.1 3.5 5.9 29.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein KASH_CCD PF14662.6 KXZ52502.1 - 3.3 7.5 33.2 0.17 11.7 14.7 2.4 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH HMG_box_5 PF14887.6 KXZ52502.1 - 3.3 7.7 5.9 13 5.8 3.7 2.8 2 0 0 2 2 2 0 HMG (high mobility group) box 5 GAS PF13851.6 KXZ52502.1 - 3.8 6.8 30.5 6.5 6.1 12.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HEAT_PBS PF03130.16 KXZ52502.1 - 5 8.1 9.1 21 6.2 4.7 3.9 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat SHE3 PF17078.5 KXZ52502.1 - 6.4 6.4 13.9 3.6 7.2 0.2 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Allexi_40kDa PF05549.11 KXZ52502.1 - 6.6 6.1 7.8 9 5.7 2.7 2.6 3 0 0 3 3 3 0 Allexivirus 40kDa protein HAP1_N PF04849.13 KXZ52502.1 - 7.1 5.7 26.9 5.7 6.0 13.5 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region JIP_LZII PF16471.5 KXZ52502.1 - 9.2 6.5 19.9 1.9 8.7 4.6 3.2 1 1 1 3 3 3 0 JNK-interacting protein leucine zipper II CBF PF03914.17 KXZ52504.1 - 1.8e-16 60.6 0.0 2.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 CBF/Mak21 family Ion_trans PF00520.31 KXZ52505.1 - 0.045 13.0 5.6 0.12 11.6 5.6 1.6 1 1 0 1 1 1 0 Ion transport protein PKD_channel PF08016.12 KXZ52505.1 - 0.6 8.7 1.6 0.89 8.2 1.6 1.1 1 0 0 1 1 1 0 Polycystin cation channel APH PF01636.23 KXZ52509.1 - 0.006 16.5 2.0 0.06 13.3 1.3 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF3531 PF12049.8 KXZ52510.1 - 1e-26 93.6 0.6 1.8e-26 92.8 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3531) zf-HC5HC2H PF13771.6 KXZ52511.1 - 4.6e-13 49.2 3.0 4.6e-13 49.2 3.0 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KXZ52511.1 - 1.6e-09 37.9 6.1 4.3e-09 36.5 6.0 1.7 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.6 KXZ52512.1 - 9.5e-12 44.6 14.8 1.4e-11 44.1 14.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ52512.1 - 2.6e-07 30.4 13.6 4e-07 29.8 13.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ52512.1 - 7.5e-05 23.0 13.5 0.00014 22.2 13.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ52512.1 - 0.009 15.8 14.7 0.015 15.1 14.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ52512.1 - 0.035 14.1 13.0 0.06 13.3 13.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain MTBP_C PF14920.6 KXZ52512.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 MDM2-binding zf-P11 PF03854.14 KXZ52512.1 - 0.46 10.2 8.0 0.81 9.4 8.0 1.4 1 0 0 1 1 1 0 P-11 zinc finger SET PF00856.28 KXZ52514.1 - 0.01 16.3 0.0 0.033 14.6 0.0 1.7 1 1 0 1 1 1 0 SET domain Mito_carr PF00153.27 KXZ52515.1 - 2.7e-17 62.5 4.3 1.1e-05 25.3 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein TmoB PF06234.12 KXZ52515.1 - 0.026 14.6 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) NCD3G PF07562.14 KXZ52516.1 - 0.0019 18.2 10.1 0.0046 16.9 10.1 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Toxin_23 PF08093.11 KXZ52516.1 - 0.029 14.5 1.3 0.029 14.5 1.3 2.3 2 0 0 2 2 2 0 Magi 5 toxic peptide family ATG13 PF10033.9 KXZ52518.1 - 2.1e-09 37.4 0.0 5e-07 29.7 0.0 2.0 1 1 1 2 2 2 2 Autophagy-related protein 13 Apq12 PF12716.7 KXZ52519.1 - 0.41 10.6 3.3 0.9 9.5 3.3 1.6 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Ank_3 PF13606.6 KXZ52520.1 - 2.7e-06 27.3 0.3 0.084 13.5 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ion_trans PF00520.31 KXZ52520.1 - 4.3e-05 22.9 4.6 8.2e-05 22.0 4.6 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KXZ52520.1 - 0.0001 22.8 0.0 0.0063 17.1 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) PKD_channel PF08016.12 KXZ52520.1 - 0.00087 18.1 4.0 0.0011 17.7 3.0 1.6 2 0 0 2 2 2 1 Polycystin cation channel Ank PF00023.30 KXZ52520.1 - 0.0009 19.6 0.0 0.87 10.1 0.0 3.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXZ52520.1 - 0.0023 18.2 0.0 2.1 8.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ52521.1 - 4.5e-07 29.7 1.1 0.096 13.3 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 KXZ52521.1 - 3.9e-06 27.4 0.1 0.00059 20.4 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ52521.1 - 4.2e-06 26.9 0.1 0.012 16.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 KXZ52521.1 - 2.5e-05 23.6 6.6 4.4e-05 22.8 6.6 1.4 1 0 0 1 1 1 1 Ion transport protein Ank PF00023.30 KXZ52521.1 - 7.4e-05 23.0 0.1 1 10.0 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat PKD_channel PF08016.12 KXZ52521.1 - 0.0068 15.1 6.1 0.01 14.5 3.6 2.0 2 0 0 2 2 2 1 Polycystin cation channel ClpS PF02617.17 KXZ52521.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS SET PF00856.28 KXZ52522.1 - 0.0033 17.8 0.3 0.12 12.8 0.0 2.4 2 0 0 2 2 2 1 SET domain CDK2AP PF09806.9 KXZ52522.1 - 0.9 9.6 9.5 1.6 8.7 9.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF945 PF06097.11 KXZ52522.1 - 1.3 8.1 5.3 3.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF945) Guanylate_cyc PF00211.20 KXZ52523.1 - 2.2e-54 183.9 0.0 3.8e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ52524.1 - 4.2e-54 183.0 0.0 6e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ENOD93 PF03386.14 KXZ52524.1 - 0.17 11.8 1.0 0.74 9.7 0.2 2.2 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein VRR_NUC PF08774.11 KXZ52525.1 - 1.5e-22 79.7 0.0 2.6e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 VRR-NUC domain TPR_2 PF07719.17 KXZ52525.1 - 3.3 8.0 8.0 2.5 8.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RCC1 PF00415.18 KXZ52526.1 - 3.5e-26 91.6 24.5 2.9e-09 37.4 0.2 8.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ52526.1 - 3.1e-21 74.6 37.0 1.8e-08 34.0 0.4 8.7 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Sulfotransfer_1 PF00685.27 KXZ52526.1 - 7.8e-11 41.9 0.1 5.1e-10 39.3 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ52526.1 - 6.2e-06 26.7 0.1 5.1e-05 23.8 0.1 2.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KXZ52526.1 - 0.063 13.2 1.5 0.13 12.2 1.5 1.5 1 1 0 1 1 1 0 Sulfotransferase family PRR18 PF15671.5 KXZ52526.1 - 1.2 8.9 15.6 3.6 7.4 15.6 1.7 1 0 0 1 1 1 0 Proline-rich protein family 18 Ribosomal_S10 PF00338.22 KXZ52528.1 - 1e-28 99.4 0.3 1.2e-28 99.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CinA_KH PF18146.1 KXZ52528.1 - 0.15 12.3 0.1 15 5.8 0.1 2.3 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Ribosomal_S10 PF00338.22 KXZ52529.1 - 1.1e-25 89.7 1.6 8.7e-16 58.0 0.3 3.0 1 1 1 2 2 2 2 Ribosomal protein S10p/S20e DUF3420 PF11900.8 KXZ52529.1 - 0.1 12.8 0.2 2.4 8.3 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3420) YbbR PF07949.12 KXZ52529.1 - 0.14 12.5 3.8 3.3 8.1 0.5 2.9 2 1 1 3 3 3 0 YbbR-like protein UPF0016 PF01169.19 KXZ52531.1 - 1.5e-38 130.9 23.2 9.9e-20 70.7 6.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ribosomal_S5_C PF03719.15 KXZ52532.1 - 5.5e-21 73.8 0.8 9.8e-21 73.0 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXZ52532.1 - 9.5e-21 73.6 3.2 2.1e-20 72.5 3.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Kinesin PF00225.23 KXZ52536.1 - 2.9e-34 118.5 0.0 3.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ52536.1 - 1.5e-08 34.7 0.0 2.6e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Microtubule binding EAP30 PF04157.16 KXZ52537.1 - 6.5 6.0 5.8 8.6 5.6 3.4 1.9 1 1 1 2 2 2 0 EAP30/Vps36 family CC2D2AN-C2 PF15625.6 KXZ52538.1 - 5.6e-19 68.5 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain SUIM_assoc PF16619.5 KXZ52538.1 - 2.1 8.5 19.3 0.013 15.5 3.6 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 LRR_8 PF13855.6 KXZ52539.1 - 0.047 13.5 6.6 0.41 10.5 0.2 3.2 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 KXZ52539.1 - 0.075 13.1 1.1 0.63 10.2 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Tim44 PF04280.15 KXZ52540.1 - 1.4e-15 57.7 0.0 4.3e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain YtxH PF12732.7 KXZ52540.1 - 0.026 15.0 1.4 1.7 9.2 0.1 2.4 2 0 0 2 2 2 0 YtxH-like protein TBCC_N PF16752.5 KXZ52540.1 - 0.074 13.5 1.0 0.15 12.5 0.7 1.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Smac_DIABLO PF09057.10 KXZ52541.1 - 0.015 14.7 0.7 0.015 14.7 0.7 2.0 1 1 1 2 2 2 0 Second Mitochondria-derived Activator of Caspases PAP1 PF08601.10 KXZ52541.1 - 0.037 13.7 11.3 0.043 13.6 11.3 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 MACPF PF01823.19 KXZ52541.1 - 0.42 10.7 11.8 0.55 10.3 11.8 1.3 1 0 0 1 1 1 0 MAC/Perforin domain DDHD PF02862.17 KXZ52541.1 - 0.42 10.7 11.0 0.55 10.4 11.0 1.2 1 0 0 1 1 1 0 DDHD domain MID_MedPIWI PF18296.1 KXZ52541.1 - 0.46 10.2 7.7 0.56 10.0 7.7 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Macoilin PF09726.9 KXZ52541.1 - 0.68 8.4 17.6 0.85 8.1 17.6 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 KXZ52541.1 - 1.2 6.1 10.5 1.4 5.9 10.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3807 PF12720.7 KXZ52541.1 - 1.3 9.3 22.7 1.7 8.9 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SRP-alpha_N PF04086.13 KXZ52541.1 - 1.7 8.5 25.0 2.3 8.1 25.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase_fungal PF17667.1 KXZ52541.1 - 2 7.1 13.7 2.4 6.9 13.7 1.0 1 0 0 1 1 1 0 Fungal protein kinase Paf1 PF03985.13 KXZ52541.1 - 3 6.7 21.1 4.2 6.2 21.1 1.3 1 0 0 1 1 1 0 Paf1 DUF2347 PF09804.9 KXZ52541.1 - 3.2 7.2 8.7 3.8 7.0 8.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SAPS PF04499.15 KXZ52541.1 - 3.9 6.2 14.8 4.4 6.0 14.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paramyxo_ncap PF00973.19 KXZ52541.1 - 4.5 6.1 8.7 5.1 5.9 8.7 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CRT10 PF08728.10 KXZ52541.1 - 5 5.2 7.3 5.5 5.0 7.3 1.0 1 0 0 1 1 1 0 CRT10 V_ATPase_I PF01496.19 KXZ52541.1 - 5.4 4.8 9.9 6.3 4.6 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2151 PF10221.9 KXZ52541.1 - 5.8 5.4 12.8 6.6 5.2 12.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RAP1 PF07218.11 KXZ52541.1 - 6.2 5.0 14.1 7 4.8 14.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF5427 PF10310.9 KXZ52541.1 - 7.1 5.5 25.5 8.7 5.2 25.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 KXZ52541.1 - 7.2 5.5 14.8 8.3 5.3 14.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SR-25 PF10500.9 KXZ52541.1 - 8 6.0 46.6 0.58 9.7 41.4 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 KXZ52541.1 - 8.3 6.4 9.4 9.8 6.2 9.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Miga PF10265.9 KXZ52541.1 - 8.9 5.1 11.8 10 4.9 11.8 1.1 1 0 0 1 1 1 0 Mitoguardin Transformer PF06495.11 KXZ52541.1 - 9.3 6.3 16.4 13 5.8 16.4 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein ALMT PF11744.8 KXZ52541.1 - 9.7 4.9 10.7 11 4.7 10.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UCR_hinge PF02320.16 KXZ52542.1 - 8.8e-22 77.1 4.9 1e-21 76.9 4.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein NIF PF03031.18 KXZ52543.1 - 0.1 12.3 0.0 0.38 10.5 0.0 1.9 3 0 0 3 3 3 0 NLI interacting factor-like phosphatase Kinesin PF00225.23 KXZ52544.1 - 1.3e-103 346.4 0.0 1.3e-103 346.4 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ52544.1 - 4.2e-55 185.8 0.2 2.3e-54 183.4 0.0 2.4 2 1 0 2 2 2 1 Microtubule binding Bacillus_HBL PF05791.11 KXZ52544.1 - 0.00011 22.1 21.1 0.034 14.0 4.8 3.6 2 1 1 3 3 3 3 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 KXZ52544.1 - 0.00073 18.5 58.9 0.054 12.4 9.0 3.5 2 1 2 4 4 4 3 Spc7 kinetochore protein DASH_Hsk3 PF08227.11 KXZ52544.1 - 0.0014 18.9 11.1 0.15 12.4 0.7 4.5 4 0 0 4 4 3 2 DASH complex subunit Hsk3 like CENP-F_leu_zip PF10473.9 KXZ52544.1 - 0.0045 17.0 60.8 0.14 12.2 3.2 5.0 2 1 3 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KXZ52544.1 - 0.0068 15.7 8.0 0.0068 15.7 8.0 4.6 2 1 3 5 5 5 1 Protein of unknown function (DUF3450) DUF2353 PF09789.9 KXZ52544.1 - 0.082 12.2 45.5 0.5 9.7 33.0 2.7 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF4618 PF15397.6 KXZ52544.1 - 0.12 11.8 40.6 0.029 13.8 21.2 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) CALCOCO1 PF07888.11 KXZ52544.1 - 0.13 11.1 60.1 0.12 11.2 24.8 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Syntaxin-18_N PF10496.9 KXZ52544.1 - 0.47 10.7 4.1 20 5.5 0.2 3.3 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus FPP PF05911.11 KXZ52544.1 - 3.6 5.7 44.9 11 4.0 14.0 2.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil IFT57 PF10498.9 KXZ52544.1 - 3.9 6.3 43.6 6.2 5.7 7.1 3.3 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 DUF5347 PF17282.2 KXZ52544.1 - 4.7 7.6 8.7 0.67 10.3 1.8 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5347) Golgin_A5 PF09787.9 KXZ52544.1 - 5.5 6.4 55.4 9.3 5.6 14.7 3.4 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KXZ52544.1 - 6.9 6.7 29.3 2.1 8.4 2.3 4.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF1943 PF09172.11 KXZ52544.1 - 7.5 5.7 15.4 0.33 10.2 8.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) TPR_MLP1_2 PF07926.12 KXZ52544.1 - 7.7 6.6 64.9 2.4 8.2 13.8 4.7 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 KXZ52544.1 - 8.7 6.9 18.5 26 5.3 0.6 5.4 4 1 2 6 6 5 0 Nucleopolyhedrovirus P10 protein HAD_2 PF13419.6 KXZ52545.1 - 4.3e-23 82.3 0.0 9.3e-23 81.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ52545.1 - 5.5e-15 56.2 0.1 1.2e-14 55.1 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ52545.1 - 1.8e-06 27.9 0.0 5.2e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_phosphat_B PF03767.14 KXZ52545.1 - 0.00097 18.8 0.0 0.002 17.8 0.0 1.4 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.7 KXZ52545.1 - 0.0053 17.2 0.0 0.016 15.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXZ52545.1 - 0.13 12.3 0.0 6.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Thioredoxin PF00085.20 KXZ52546.1 - 4.2e-07 29.9 0.0 4.5e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ52546.1 - 0.037 14.5 0.0 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 KXZ52547.1 - 0.0055 16.7 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin PhoLip_ATPase_C PF16212.5 KXZ52548.1 - 2.7e-69 233.7 19.5 2.7e-69 233.7 19.5 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXZ52548.1 - 2.2e-27 94.5 0.4 6.5e-27 93.0 0.4 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXZ52548.1 - 1.9e-10 40.7 0.0 2e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXZ52548.1 - 2.4e-10 41.0 2.3 0.00027 21.3 0.7 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXZ52548.1 - 0.0008 19.0 0.4 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXZ52548.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-piccolo PF05715.13 KXZ52548.1 - 1.1 9.4 6.9 13 6.1 0.6 2.5 2 0 0 2 2 2 0 Piccolo Zn-finger Epimerase PF01370.21 KXZ52549.1 - 3.6e-23 82.3 0.0 6.4e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ52549.1 - 4.3e-20 72.4 0.0 1.3e-19 70.8 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXZ52549.1 - 0.0003 20.0 0.0 0.0023 17.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.14 KXZ52549.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXZ52549.1 - 0.12 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1929 PF09118.11 KXZ52550.1 - 4.3e-19 68.6 0.1 8e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 KXZ52550.1 - 2.8e-12 46.3 0.2 1.2e-10 41.0 0.0 2.9 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 KXZ52550.1 - 0.0041 17.1 1.3 16 5.6 0.0 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain RPE65 PF03055.15 KXZ52551.1 - 1.1e-107 361.2 0.0 1.3e-107 360.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein 2OG-FeII_Oxy_3 PF13640.6 KXZ52552.1 - 0.0013 19.6 0.0 0.013 16.4 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily VID27 PF08553.10 KXZ52553.1 - 4e-48 164.3 0.0 7.2e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain WD40 PF00400.32 KXZ52553.1 - 0.00084 20.1 1.8 1.8 9.5 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat RE_HindVP PF09519.10 KXZ52553.1 - 0.088 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease VID27_PH PF17747.1 KXZ52556.1 - 0.038 14.3 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 VID27 PH-like domain Orai-1 PF07856.12 KXZ52557.1 - 4.1e-30 104.7 0.2 5.8e-30 104.2 0.2 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Jiraiya PF15038.6 KXZ52557.1 - 5.7e-05 22.6 1.9 0.036 13.5 0.4 2.3 2 0 0 2 2 2 2 Jiraiya DnaJ PF00226.31 KXZ52559.1 - 0.071 13.2 0.0 0.28 11.3 0.0 2.1 1 0 0 1 1 1 0 DnaJ domain TFIID_30kDa PF03540.13 KXZ52560.1 - 4.2e-21 74.6 0.1 5.9e-20 70.9 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Acetyltransf_1 PF00583.25 KXZ52562.1 - 2.2e-15 56.9 0.0 2.5e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXZ52562.1 - 7.1e-10 39.2 0.0 8.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ52562.1 - 1.1e-09 38.3 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ52562.1 - 7.6e-07 29.0 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXZ52562.1 - 0.0022 18.1 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXZ52562.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXZ52562.1 - 0.051 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KXZ52562.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DapB_N PF01113.20 KXZ52563.1 - 3.6e-08 33.6 0.0 7.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DapB_C PF05173.14 KXZ52563.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus RRM_1 PF00076.22 KXZ52564.1 - 1.4e-20 72.9 0.1 2.4e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 KXZ52564.1 - 2.1e-11 44.3 7.7 2.1e-11 44.3 7.7 2.8 2 2 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_8 PF11835.8 KXZ52564.1 - 0.061 13.5 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain TPR_12 PF13424.6 KXZ52566.1 - 3.9e-46 155.2 21.5 1.1e-18 67.3 1.0 5.1 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ52566.1 - 2.6e-43 144.7 18.6 4.4e-11 42.3 0.0 5.8 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ52566.1 - 3.9e-14 51.6 8.2 0.0091 16.0 0.9 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ52566.1 - 1.1e-12 47.0 7.1 0.0083 16.3 0.3 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ52566.1 - 4.5e-12 46.0 3.7 4.5e-12 46.0 3.7 1.9 2 0 0 2 2 2 1 MalT-like TPR region TPR_2 PF07719.17 KXZ52566.1 - 4.6e-11 42.0 18.6 0.00023 21.1 1.9 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ52566.1 - 1.7e-10 40.2 10.2 0.0081 15.9 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ52566.1 - 3.8e-07 30.5 15.8 0.00017 22.0 0.3 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ52566.1 - 2.7e-06 27.9 45.8 0.073 13.7 13.7 7.0 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ52566.1 - 0.00031 20.4 5.8 0.048 13.3 0.1 4.1 4 1 1 5 5 5 1 TPR repeat PPR PF01535.20 KXZ52566.1 - 0.00055 20.0 0.0 0.95 9.9 0.0 3.7 4 0 0 4 4 3 1 PPR repeat TPR_4 PF07721.14 KXZ52566.1 - 0.0013 19.1 45.4 0.16 12.7 0.9 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ52566.1 - 0.0015 18.8 5.4 0.15 12.5 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ52566.1 - 0.0039 17.9 34.4 0.48 11.4 1.8 6.9 6 1 2 8 8 7 3 Tetratricopeptide repeat PPR_1 PF12854.7 KXZ52566.1 - 0.0059 16.3 1.4 1.6 8.5 0.0 3.6 4 0 0 4 4 4 1 PPR repeat TPR_5 PF12688.7 KXZ52566.1 - 0.0073 16.5 3.2 0.047 13.9 0.4 3.1 2 1 0 2 2 2 1 Tetratrico peptide repeat MFS_1 PF07690.16 KXZ52567.1 - 1.7e-25 89.7 40.4 1.7e-25 89.7 40.4 3.5 1 1 1 2 2 2 1 Major Facilitator Superfamily P5-ATPase PF12409.8 KXZ52567.1 - 0.97 9.6 4.3 0.16 12.0 0.3 1.7 2 0 0 2 2 2 0 P5-type ATPase cation transporter Ycf66_N PF07444.11 KXZ52568.1 - 2.4e-16 59.6 2.3 3.3e-16 59.2 2.3 1.2 1 0 0 1 1 1 1 Ycf66 protein N-terminus DUF2157 PF09925.9 KXZ52568.1 - 0.083 12.7 0.7 0.14 11.9 0.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) SnoaL PF07366.12 KXZ52569.1 - 2e-14 53.4 0.0 4.9e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXZ52569.1 - 2.4e-10 40.9 1.6 6.9e-10 39.5 0.0 2.1 1 1 1 2 2 2 1 SnoaL-like domain PRIMA1 PF16101.5 KXZ52569.1 - 0.035 14.1 0.4 0.079 13.0 0.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyco_hydro_9 PF00759.19 KXZ52569.1 - 0.66 9.3 10.3 0.83 9.0 10.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DinB_2 PF12867.7 KXZ52569.1 - 4.3 7.8 9.8 0.71 10.4 1.4 2.7 1 1 2 3 3 3 0 DinB superfamily Ion_trans PF00520.31 KXZ52570.1 - 6.3e-10 38.7 20.0 1.2e-09 37.8 20.0 1.5 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KXZ52570.1 - 1.3e-09 38.5 0.3 1.7e-07 31.8 0.2 3.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ52570.1 - 2.8e-07 30.7 0.4 0.037 14.5 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXZ52570.1 - 1.8e-06 27.8 3.1 3.6 8.5 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXZ52570.1 - 1.8e-05 24.9 0.8 0.11 12.9 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ52570.1 - 6.6e-05 23.4 0.7 0.28 11.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 KXZ52570.1 - 0.013 14.2 16.2 0.021 13.5 16.2 1.3 1 0 0 1 1 1 0 Polycystin cation channel LCM PF04072.14 KXZ52571.1 - 7.4e-25 88.0 0.0 5.3e-20 72.2 0.0 2.8 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase VASt PF16016.5 KXZ52573.1 - 5.8e-29 101.5 0.0 7.3e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Alpha_kinase PF02816.18 KXZ52574.1 - 3.3e-30 105.6 0.0 5.4e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family zf-CCCH_4 PF18044.1 KXZ52574.1 - 6.7e-15 54.5 22.8 1.2e-05 25.0 5.5 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXZ52574.1 - 4e-10 39.4 37.2 0.00014 21.8 5.3 3.5 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KXZ52574.1 - 2.1e-06 27.5 22.0 0.00082 19.2 1.2 3.6 1 1 2 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXZ52574.1 - 0.028 15.1 18.4 0.46 11.2 0.4 3.5 1 1 2 3 3 3 0 Torus domain Band_7 PF01145.25 KXZ52574.1 - 0.23 11.5 0.9 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 SPFH domain / Band 7 family zf-CCCH_3 PF15663.5 KXZ52574.1 - 0.29 11.3 19.0 0.096 12.9 10.8 2.9 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXZ52574.1 - 0.61 10.7 30.5 0.096 13.2 4.0 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger DUF3235 PF11574.8 KXZ52574.1 - 3.6 8.5 5.1 5 8.1 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Alpha_kinase PF02816.18 KXZ52575.1 - 8.1e-08 32.6 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family Band_7 PF01145.25 KXZ52575.1 - 1.9 8.5 4.2 3.2 7.7 1.4 2.4 1 1 1 2 2 2 0 SPFH domain / Band 7 family zf-CCCH_4 PF18044.1 KXZ52576.1 - 1.8e-08 34.0 16.6 2.4e-05 24.0 4.5 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXZ52576.1 - 8.9e-08 31.9 22.9 0.00076 19.5 8.6 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KXZ52576.1 - 1.3e-06 28.2 23.3 0.00029 20.7 5.3 2.8 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXZ52576.1 - 6.1e-05 23.7 9.1 0.012 16.3 1.5 2.2 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KXZ52576.1 - 0.0075 16.7 16.9 0.018 15.5 3.3 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCHH PF10283.9 KXZ52576.1 - 0.022 14.8 1.9 0.022 14.8 1.9 1.9 2 0 0 2 2 2 0 PBZ domain Disintegrin PF00200.23 KXZ52576.1 - 7 7.5 10.3 0.083 13.7 2.6 1.8 3 0 0 3 3 3 0 Disintegrin Pyr_redox_3 PF13738.6 KXZ52581.1 - 2.5e-13 50.0 0.0 7.4e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXZ52581.1 - 1.8e-11 43.8 1.7 5.5e-05 22.5 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXZ52581.1 - 7.6e-11 41.1 0.1 1.5e-06 27.0 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXZ52581.1 - 5e-10 39.5 0.1 1.5e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ52581.1 - 1.3e-08 34.9 3.2 6.1e-06 26.1 0.7 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXZ52581.1 - 5.7e-08 33.2 2.5 1.9e-06 28.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ52581.1 - 2.4e-06 26.9 0.1 0.0001 21.6 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXZ52581.1 - 0.00011 21.0 0.1 0.00018 20.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KXZ52581.1 - 0.00026 20.4 0.0 0.00043 19.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KXZ52581.1 - 0.00034 20.0 0.1 0.0018 17.6 0.1 2.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXZ52581.1 - 0.0014 18.1 0.2 0.0014 18.1 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXZ52581.1 - 0.0024 17.9 0.1 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXZ52581.1 - 0.0045 16.2 0.4 0.023 13.9 0.1 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KXZ52581.1 - 0.014 14.5 0.4 0.014 14.5 0.4 1.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 KXZ52581.1 - 0.019 14.2 0.1 0.019 14.2 0.1 2.3 2 1 0 2 2 1 0 Thi4 family 3HCDH_N PF02737.18 KXZ52581.1 - 0.026 14.4 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KXZ52581.1 - 0.054 12.7 0.5 0.2 10.9 0.1 1.9 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KXZ52581.1 - 0.079 12.0 0.3 0.48 9.4 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein RRM_1 PF00076.22 KXZ52582.1 - 4.5e-14 52.0 0.0 5.3e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U-box PF04564.15 KXZ52582.1 - 8.5e-14 51.5 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXZ52582.1 - 0.00014 21.6 0.0 0.00065 19.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KXZ52582.1 - 0.00058 19.9 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KXZ52582.1 - 0.46 9.8 1.2 0.71 9.2 0.0 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger TFIIA PF03153.13 KXZ52582.1 - 1.9 8.4 22.3 0.73 9.8 17.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Oxysterol_BP PF01237.18 KXZ52585.1 - 6.9e-14 51.5 3.4 7.6e-14 51.3 3.4 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.18 KXZ52586.1 - 8.8e-68 228.8 0.0 1.2e-67 228.4 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KXZ52586.1 - 2.1e-05 25.0 0.0 3.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PH domain Complex1_LYR PF05347.15 KXZ52588.1 - 0.007 16.4 0.1 0.0096 16.0 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) CcmD PF04995.14 KXZ52589.1 - 0.03 14.4 1.8 0.03 14.4 1.8 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) ABC2_membrane PF01061.24 KXZ52591.1 - 1.7e-35 122.3 16.8 2.6e-35 121.7 16.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ52591.1 - 3.1e-25 89.3 0.0 5e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXZ52591.1 - 0.003 16.7 15.1 0.0054 15.9 15.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 KXZ52591.1 - 0.057 13.8 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXZ52591.1 - 0.071 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KXZ52591.1 - 0.077 12.7 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.6 KXZ52591.1 - 0.098 12.5 3.4 0.97 9.2 0.2 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ52591.1 - 0.21 11.0 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Nop14 PF04147.12 KXZ52592.1 - 0.24 9.6 1.2 0.33 9.1 1.2 1.1 1 0 0 1 1 1 0 Nop14-like family INSC_LBD PF16748.5 KXZ52593.1 - 0.21 11.1 0.3 16 5.0 0.1 2.2 1 1 1 2 2 2 0 Inscuteable LGN-binding domain BUD22 PF09073.10 KXZ52594.1 - 1.4 8.2 15.4 2 7.7 15.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KXZ52594.1 - 9.2 5.6 19.4 12 5.2 19.4 1.1 1 0 0 1 1 1 0 SDA1 DUF5327 PF17261.2 KXZ52595.1 - 7.9 7.3 7.3 25 5.7 7.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Sec63 PF02889.16 KXZ52597.1 - 1.5e-58 198.0 0.0 1.8e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain Pkinase PF00069.25 KXZ52598.1 - 1.9e-48 165.2 0.0 2.6e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52598.1 - 2.9e-25 89.0 0.0 4.9e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ52598.1 - 1.1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ52598.1 - 7.4e-06 25.0 0.0 1.8e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXZ52598.1 - 0.021 14.7 0.1 0.021 14.7 0.1 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ52598.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ52599.1 - 3.5e-26 92.0 0.0 7.8e-26 90.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ52599.1 - 2.3e-20 73.1 0.0 2.1e-19 69.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ52599.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH_6_hur PF04655.14 KXZ52599.1 - 0.046 13.1 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Kdo PF06293.14 KXZ52599.1 - 0.049 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ52599.1 - 0.96 9.3 10.7 0.095 12.6 4.6 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family HTH_32 PF13565.6 KXZ52600.1 - 0.38 11.4 3.6 1.5 9.5 1.2 3.4 2 0 0 2 2 2 0 Homeodomain-like domain Guanylate_cyc PF00211.20 KXZ52602.1 - 2.8e-55 186.8 0.0 4.8e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ52603.1 - 6.7e-43 146.4 0.0 1.1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3707 PF12499.8 KXZ52605.1 - 3e-22 79.7 4.1 3.9e-22 79.3 4.1 1.1 1 0 0 1 1 1 1 Pherophorin JmjC PF02373.22 KXZ52607.1 - 4.7e-11 43.1 0.0 8.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JAB PF01398.21 KXZ52608.1 - 2.6e-21 75.8 0.3 3.6e-21 75.3 0.3 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXZ52608.1 - 0.00055 20.3 0.9 0.39 11.2 0.2 2.6 2 1 1 3 3 3 2 Maintenance of mitochondrial structure and function hnRNP_Q_AcD PF18360.1 KXZ52609.1 - 0.0059 16.5 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain XPC-binding PF09280.11 KXZ52609.1 - 0.2 11.4 1.2 0.67 9.7 1.2 1.9 1 0 0 1 1 1 0 XPC-binding domain Kin17_mid PF10357.9 KXZ52610.1 - 1e-46 157.9 4.1 1.8e-46 157.2 4.1 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 KXZ52610.1 - 3.8e-21 75.0 2.9 8e-21 73.9 2.4 1.8 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain NdhS PF11623.8 KXZ52610.1 - 0.064 12.9 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S KOW PF00467.29 KXZ52610.1 - 0.48 10.4 0.0 0.48 10.4 0.0 3.8 4 1 0 4 4 4 0 KOW motif PIEZO PF15917.5 KXZ52610.1 - 1.5 8.3 4.6 2.6 7.5 4.6 1.3 1 0 0 1 1 1 0 Piezo NDK PF00334.19 KXZ52611.1 - 1.1e-45 154.9 0.0 1.9e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase IQ PF00612.27 KXZ52611.1 - 5.1e-11 41.4 0.8 0.00017 21.1 0.1 2.5 2 0 0 2 2 2 2 IQ calmodulin-binding motif Dpy-30 PF05186.13 KXZ52611.1 - 1.2e-07 31.2 0.3 5.2e-07 29.3 0.3 2.1 2 1 0 2 2 2 1 Dpy-30 motif TFIIA PF03153.13 KXZ52611.1 - 2.7 7.9 10.3 4.1 7.3 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Adeno_E3_CR2 PF02439.15 KXZ52613.1 - 0.00046 19.9 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.12 KXZ52613.1 - 0.0069 16.2 0.0 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KXZ52613.1 - 0.27 10.7 6.4 0.71 9.3 6.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain OAD_gamma PF04277.13 KXZ52613.1 - 0.57 10.8 5.2 6.3 7.5 0.0 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain LRR_4 PF12799.7 KXZ52614.1 - 0.41 11.1 8.0 8.4 7.0 0.3 3.8 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) TRM13 PF05206.14 KXZ52615.1 - 5.3e-45 154.0 0.0 4.1e-27 95.3 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase TRM13 Methyltransf_32 PF13679.6 KXZ52615.1 - 1.1e-05 25.4 0.2 0.00012 22.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KXZ52615.1 - 0.31 10.8 0.2 0.52 10.0 0.2 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PDDEXK_6 PF04720.12 KXZ52616.1 - 2.5e-12 47.2 0.0 3.4e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 PDDEXK-like family of unknown function RcbX PF02341.15 KXZ52617.1 - 0.00089 19.5 0.0 1.9 8.8 0.1 2.3 2 0 0 2 2 2 2 RbcX protein C2 PF00168.30 KXZ52619.1 - 1.7e-06 28.2 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain DEAD PF00270.29 KXZ52621.1 - 4.5e-08 33.1 0.0 7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ52621.1 - 0.2 12.0 0.0 0.49 10.8 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain CDC45 PF02724.14 KXZ52622.1 - 0.41 8.9 8.0 0.5 8.6 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 KXZ52622.1 - 6.3 6.6 13.5 10 5.9 13.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pentapeptide PF00805.22 KXZ52623.1 - 4.9e-29 99.6 19.0 2e-10 40.1 3.0 4.0 2 1 3 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KXZ52623.1 - 4.6e-12 45.9 0.2 1.9e-10 40.7 0.1 2.8 1 1 2 3 3 3 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KXZ52623.1 - 1.4e-11 44.4 7.1 2.3e-05 24.5 1.0 3.8 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) WD40 PF00400.32 KXZ52624.1 - 0.002 18.9 5.9 1.3 10.0 0.2 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Spt20 PF12090.8 KXZ52624.1 - 0.83 9.2 7.8 1.2 8.7 7.8 1.1 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 KXZ52626.1 - 8.1e-11 41.8 0.0 9.3e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52626.1 - 7.4e-10 38.5 0.0 8.6e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Nucleoporin_FG2 PF15967.5 KXZ52627.1 - 0.0029 16.2 4.3 0.004 15.8 4.3 1.1 1 0 0 1 1 1 1 Nucleoporin FG repeated region Pkinase_Tyr PF07714.17 KXZ52628.1 - 2.8e-13 49.7 0.0 5.5e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ52628.1 - 4.9e-13 49.1 0.0 9.2e-13 48.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52630.1 - 5.4e-11 42.3 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ52630.1 - 7.2e-11 42.0 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KXZ52631.1 - 5.4e-14 52.2 0.0 2.1e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52631.1 - 5.1e-13 48.9 0.0 4.7e-10 39.2 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase FrhB_FdhB_N PF04422.13 KXZ52631.1 - 0.15 12.2 0.4 7 6.9 0.1 2.7 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Tektin PF03148.14 KXZ52634.1 - 2.7e-64 217.3 20.2 2.7e-64 217.3 20.2 1.5 2 0 0 2 2 2 1 Tektin family AAA_13 PF13166.6 KXZ52634.1 - 4.3e-05 22.4 13.9 0.0065 15.2 0.9 2.1 2 0 0 2 2 2 2 AAA domain Osmo_CC PF08946.10 KXZ52634.1 - 0.039 14.2 3.1 33 4.8 0.1 4.0 4 0 0 4 4 3 0 Osmosensory transporter coiled coil ADIP PF11559.8 KXZ52634.1 - 0.041 14.0 1.3 0.041 14.0 1.3 4.3 3 2 1 4 4 4 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 KXZ52634.1 - 0.042 14.1 12.0 1.9 8.9 0.3 4.2 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KXZ52634.1 - 0.1 13.2 0.3 0.1 13.2 0.3 4.7 5 1 0 5 5 5 0 SlyX DUF948 PF06103.11 KXZ52634.1 - 0.13 12.6 13.5 0.73 10.1 0.5 4.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KXZ52634.1 - 0.19 12.2 11.3 0.36 11.3 0.4 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KXZ52634.1 - 0.35 10.9 19.4 3.3 7.7 1.6 4.6 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KXZ52634.1 - 0.55 10.4 40.7 0.091 13.0 1.4 5.0 3 2 2 5 5 5 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KXZ52634.1 - 0.55 10.3 18.8 2.5 8.1 0.6 4.6 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) YlqD PF11068.8 KXZ52634.1 - 0.61 10.5 14.6 1.1 9.7 0.3 4.2 3 2 0 3 3 3 0 YlqD protein GlcNAc-1_reg PF18440.1 KXZ52634.1 - 0.7 10.2 3.5 13 6.1 0.6 3.4 3 1 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain GAS PF13851.6 KXZ52634.1 - 0.84 8.9 21.2 0.74 9.1 0.8 3.9 4 1 0 4 4 4 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KXZ52634.1 - 2.4 7.2 17.3 0.21 10.6 9.4 2.5 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF445 PF04286.12 KXZ52634.1 - 3.5 7.3 11.5 1.2 8.9 3.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DUF4407 PF14362.6 KXZ52634.1 - 3.8 6.8 24.6 1.1 8.6 14.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KXZ52634.1 - 8.4 6.9 11.6 21 5.6 0.1 4.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TPR_12 PF13424.6 KXZ52635.1 - 1.4e-87 288.0 100.5 2.8e-17 62.8 6.0 11.5 4 3 8 13 13 13 13 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ52635.1 - 4e-53 175.9 73.7 3.4e-08 33.1 0.8 14.3 14 0 0 14 14 14 12 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ52635.1 - 4.2e-15 54.6 41.7 0.041 13.9 0.2 12.8 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ52635.1 - 5.6e-15 54.2 73.9 0.033 14.3 0.5 14.3 14 1 0 14 14 14 8 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ52635.1 - 5.8e-15 54.4 47.4 0.11 12.4 0.1 13.2 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ52635.1 - 7.1e-08 32.9 98.1 0.0089 16.5 2.4 12.1 5 4 8 13 13 12 8 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ52635.1 - 3.6e-06 27.1 30.3 0.22 11.8 1.5 8.4 4 3 4 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXZ52635.1 - 4.9e-06 27.1 144.4 0.12 13.1 5.9 14.5 5 4 8 14 14 13 8 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ52635.1 - 6.9e-06 26.1 19.6 2.8 8.5 0.0 8.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ52635.1 - 7.2e-06 25.8 26.5 0.95 9.8 0.0 10.3 11 0 0 11 11 10 1 Tetratricopeptide repeat PG_binding_1 PF01471.18 KXZ52635.1 - 5e-05 23.4 0.8 0.0024 18.0 0.0 3.5 4 0 0 4 4 4 1 Putative peptidoglycan binding domain TPR_MalT PF17874.1 KXZ52635.1 - 0.0015 18.0 22.8 0.0015 18.0 22.8 5.7 1 1 3 4 4 3 3 MalT-like TPR region TPR_14 PF13428.6 KXZ52635.1 - 0.061 14.2 1.3 0.061 14.2 1.3 14.8 8 6 6 15 15 15 0 Tetratricopeptide repeat MIT PF04212.18 KXZ52635.1 - 4.2 7.5 12.0 2.7 8.1 0.1 4.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain AAA_22 PF13401.6 KXZ52636.1 - 0.024 14.9 0.0 0.31 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SIP PF04954.13 KXZ52636.1 - 0.072 13.6 0.0 25 5.4 0.0 2.8 2 0 0 2 2 2 0 Siderophore-interacting protein NADH-G_4Fe-4S_3 PF10588.9 KXZ52636.1 - 0.22 11.1 4.4 8.9 6.0 0.4 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF4795 PF16043.5 KXZ52636.1 - 0.24 11.0 0.0 28 4.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Ribosomal_S27e PF01667.17 KXZ52636.1 - 0.27 11.0 0.8 27 4.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 DUF4209 PF13910.6 KXZ52637.1 - 5.1e-06 26.6 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Ribosomal_60s PF00428.19 KXZ52637.1 - 0.0073 16.9 0.2 8.4 7.1 0.0 2.5 3 0 0 3 3 3 2 60s Acidic ribosomal protein THOC2_N PF16134.5 KXZ52637.1 - 0.013 14.1 0.0 2.7 6.5 0.0 2.1 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus Ank_2 PF12796.7 KXZ52640.1 - 3.9e-63 210.0 4.4 1.3e-14 54.5 0.3 6.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ52640.1 - 6.2e-51 164.4 4.5 5.6e-05 23.2 0.0 12.0 12 0 0 12 12 12 10 Ankyrin repeat Ank PF00023.30 KXZ52640.1 - 8.7e-48 158.8 18.1 9e-06 25.9 0.0 11.3 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 KXZ52640.1 - 1e-46 156.7 1.0 1.3e-06 28.8 0.0 8.0 4 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ52640.1 - 1.8e-41 139.6 20.3 6.4e-07 29.5 0.0 8.9 1 1 9 10 10 10 10 Ankyrin repeats (many copies) DUF1604 PF07713.13 KXZ52640.1 - 0.0071 16.1 0.6 0.033 14.0 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1604) DUF2384 PF09722.10 KXZ52640.1 - 0.017 15.1 14.1 1.2 9.2 0.1 5.9 7 0 0 7 7 7 0 Protein of unknown function (DUF2384) DUF1039 PF06287.11 KXZ52640.1 - 0.096 13.1 10.0 4.2 7.9 0.1 5.5 4 2 2 6 6 6 0 Protein of unknown function (DUF1039) Response_reg PF00072.24 KXZ52640.1 - 0.2 11.9 0.2 41 4.4 0.0 3.8 4 1 1 5 5 5 0 Response regulator receiver domain HAUS-augmin3 PF14932.6 KXZ52641.1 - 0.022 14.4 2.5 1.9 8.0 5.1 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TPR_MLP1_2 PF07926.12 KXZ52641.1 - 3.1 7.9 13.3 5.9 7.0 2.4 3.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MMR_HSR1 PF01926.23 KXZ52643.1 - 1.3e-13 51.0 0.0 1.8e-12 47.4 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ52643.1 - 0.0031 17.1 0.0 0.0085 15.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXZ52643.1 - 0.0077 16.1 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KXZ52643.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.8 1 1 0 1 1 1 0 Dynamin family Glu-tRNAGln PF02686.15 KXZ52643.1 - 0.16 12.3 0.8 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF4746 PF15928.5 KXZ52643.1 - 4 6.8 6.0 6.2 6.2 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AhpC-TSA PF00578.21 KXZ52644.1 - 4.1e-40 136.6 0.0 7.7e-37 126.0 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 KXZ52644.1 - 2.8e-21 75.5 0.0 4.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KXZ52644.1 - 2.9e-17 62.8 0.0 1.5e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Redoxin 1-cysPrx_C PF10417.9 KXZ52644.1 - 5.9e-12 45.2 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_2 PF13098.6 KXZ52644.1 - 0.0022 18.4 0.1 0.012 16.0 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ52644.1 - 0.012 16.0 0.0 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KXZ52644.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin PUF PF00806.19 KXZ52645.1 - 5.7e-67 217.8 1.6 8e-08 31.6 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat LOB PF03195.14 KXZ52645.1 - 0.073 13.7 0.9 34 5.1 0.0 4.0 3 2 1 4 4 4 0 Lateral organ boundaries (LOB) domain CPL PF08144.11 KXZ52645.1 - 0.4 11.0 3.0 16 5.9 0.2 4.0 2 2 3 5 5 5 0 CPL (NUC119) domain PTH2 PF01981.16 KXZ52646.1 - 2.8e-43 146.9 0.3 3.5e-43 146.6 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 FAD_binding_3 PF01494.19 KXZ52647.1 - 2.5e-15 56.6 4.9 5.9e-08 32.3 0.6 3.0 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXZ52647.1 - 3e-05 23.4 0.6 7.4e-05 22.1 0.4 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXZ52647.1 - 9.3e-05 22.6 0.3 0.00034 20.8 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXZ52647.1 - 0.0024 16.8 0.2 0.0063 15.4 0.3 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KXZ52647.1 - 0.0027 17.0 0.8 0.0046 16.2 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ52647.1 - 0.0058 15.8 1.0 0.0058 15.8 1.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KXZ52647.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 KXZ52647.1 - 0.026 13.6 1.6 0.041 13.0 1.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXZ52647.1 - 0.038 12.7 0.7 0.064 11.9 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KXZ52647.1 - 0.08 12.0 0.8 0.15 11.1 0.8 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KXZ52647.1 - 1.5 8.1 6.6 2.5 7.4 6.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXZ52647.1 - 2.3 7.4 5.1 0.6 9.3 1.6 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bromodomain PF00439.25 KXZ52649.1 - 6.4e-12 45.4 0.0 7.3e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Bromodomain Sigma_reg_N PF13800.6 KXZ52652.1 - 0.74 10.1 2.3 1.2 9.5 0.1 2.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Fe-ADH PF00465.19 KXZ52653.1 - 1.7e-110 369.3 0.1 1.7e-110 369.3 0.1 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 KXZ52653.1 - 1.3e-24 86.6 6.4 1e-23 83.6 6.4 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 KXZ52653.1 - 1.7e-15 57.4 0.0 2.6e-07 30.6 0.1 2.6 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KXZ52654.1 - 1.4e-110 369.6 0.1 2.6e-110 368.7 0.1 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 KXZ52654.1 - 3.3e-26 91.8 7.9 7.9e-25 87.3 7.9 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 KXZ52654.1 - 1.3e-15 57.8 0.0 2.3e-07 30.8 0.1 2.7 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Guanylate_cyc PF00211.20 KXZ52655.1 - 3.4e-54 183.3 0.0 5.4e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KXZ52656.1 - 1.8e-39 135.6 0.0 7.4e-34 117.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ52656.1 - 5.6e-36 124.3 0.0 2.4e-29 102.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ52656.1 - 0.0031 16.3 0.0 0.0046 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ52656.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH_6_hur PF04655.14 KXZ52656.1 - 0.036 13.4 4.9 0.39 10.1 0.1 3.0 3 0 0 3 3 3 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Guanylate_cyc PF00211.20 KXZ52657.1 - 5.6e-12 45.6 0.0 6.3e-06 25.9 0.0 3.3 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KXZ52658.1 - 1.5e-39 135.9 0.0 4.5e-34 117.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ52658.1 - 2e-36 125.8 0.0 4e-30 105.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ52658.1 - 0.0004 19.3 0.0 0.00046 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ52658.1 - 0.0074 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TAF4 PF05236.14 KXZ52658.1 - 6.1 6.5 5.5 9.1 5.9 5.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family UDG PF03167.19 KXZ52659.1 - 3.2e-21 75.9 0.0 5.8e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pkinase PF00069.25 KXZ52660.1 - 6.7e-07 28.9 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52660.1 - 0.00017 20.9 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ52661.1 - 2.4e-08 33.6 0.0 1.4e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52661.1 - 1.6e-05 24.4 0.0 9.6e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SET PF00856.28 KXZ52662.1 - 1.3e-10 41.9 0.0 3.3e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 SET domain Rieske PF00355.26 KXZ52663.1 - 1.8e-16 59.9 0.0 2.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ52663.1 - 3.8e-10 39.8 0.0 1.1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Pheophorbide a oxygenase PsbP PF01789.16 KXZ52663.1 - 3.6e-06 27.2 0.0 9.9e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 PsbP Peptidase_S10 PF00450.22 KXZ52665.1 - 2.7e-08 33.6 0.0 3.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase bZIP_1 PF00170.21 KXZ52666.1 - 6e-06 26.3 1.0 1.2e-05 25.4 1.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ52666.1 - 9.7e-05 22.4 2.9 0.00019 21.5 2.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXZ52666.1 - 0.0041 17.6 1.5 0.011 16.3 1.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor TPR_MLP1_2 PF07926.12 KXZ52666.1 - 4.9 7.2 11.7 10 6.2 11.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein P34-Arc PF04045.14 KXZ52667.1 - 3.5e-29 102.2 0.0 4e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc GHMP_kinases_C PF08544.13 KXZ52667.1 - 0.079 13.3 2.1 0.19 12.1 2.1 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal Methyltransf_16 PF10294.9 KXZ52668.1 - 1.1e-26 93.6 0.0 1.6e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXZ52668.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KXZ52668.1 - 0.0076 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KXZ52668.1 - 0.3 10.8 0.0 0.44 10.3 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein GRP PF07172.11 KXZ52668.1 - 5.8 7.7 33.4 10 6.9 33.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF1664 PF07889.12 KXZ52669.1 - 1.3e-05 25.3 1.4 1.7e-05 24.9 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KXZ52669.1 - 0.00012 22.1 1.3 0.0002 21.4 0.9 1.5 1 1 0 1 1 1 1 Laminin Domain II She9_MDM33 PF05546.11 KXZ52669.1 - 0.00023 21.1 2.6 0.00031 20.6 2.6 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family Vps53_N PF04100.12 KXZ52669.1 - 0.0003 19.9 3.1 0.00037 19.6 3.1 1.0 1 0 0 1 1 1 1 Vps53-like, N-terminal Uso1_p115_C PF04871.13 KXZ52669.1 - 0.0012 19.2 6.4 0.0015 18.9 6.4 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region EzrA PF06160.12 KXZ52669.1 - 0.0016 16.7 5.1 0.0019 16.4 5.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA PKK PF12474.8 KXZ52669.1 - 0.0018 18.4 9.1 0.0023 18.1 9.1 1.1 1 0 0 1 1 1 1 Polo kinase kinase COMP PF11598.8 KXZ52669.1 - 0.0024 18.3 8.0 0.25 11.8 0.3 2.7 3 0 0 3 3 2 2 Cartilage oligomeric matrix protein GCN5L1 PF06320.13 KXZ52669.1 - 0.0026 17.9 0.7 0.0026 17.9 0.7 1.9 1 1 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) WXG100 PF06013.12 KXZ52669.1 - 0.0031 17.7 0.5 0.015 15.5 0.5 2.0 1 1 0 1 1 1 1 Proteins of 100 residues with WXG UPF0242 PF06785.11 KXZ52669.1 - 0.0036 17.4 2.7 0.0047 17.1 2.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 KXZ52669.1 - 0.005 15.5 4.2 0.0056 15.3 4.2 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A OmpH PF03938.14 KXZ52669.1 - 0.0051 17.2 5.5 0.0069 16.7 5.5 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) BORCS8 PF10167.9 KXZ52669.1 - 0.0053 16.7 0.8 0.0074 16.2 0.8 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 Apolipoprotein PF01442.18 KXZ52669.1 - 0.0078 16.1 1.6 0.01 15.7 1.6 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4618 PF15397.6 KXZ52669.1 - 0.0079 15.7 3.3 0.009 15.5 2.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) LXG PF04740.12 KXZ52669.1 - 0.011 15.5 1.7 0.013 15.2 1.7 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily SHE3 PF17078.5 KXZ52669.1 - 0.011 15.4 2.0 0.016 15.0 2.0 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HIP1_clath_bdg PF16515.5 KXZ52669.1 - 0.012 16.2 5.6 0.016 15.8 5.6 1.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 KXZ52669.1 - 0.013 15.8 8.9 0.025 14.8 8.9 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 KXZ52669.1 - 0.013 15.8 0.7 0.075 13.3 0.7 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KXZ52669.1 - 0.02 13.8 6.3 0.025 13.4 6.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KXZ52669.1 - 0.026 15.1 1.9 0.044 14.3 1.9 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal YtxH PF12732.7 KXZ52669.1 - 0.03 14.9 4.1 0.063 13.8 4.1 1.7 1 1 0 1 1 1 0 YtxH-like protein COG6 PF06419.11 KXZ52669.1 - 0.032 12.4 1.3 0.038 12.2 1.3 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 CdvA PF18822.1 KXZ52669.1 - 0.033 14.0 2.2 0.033 14.0 2.2 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Vps51 PF08700.11 KXZ52669.1 - 0.033 14.3 1.5 0.096 12.8 1.3 2.0 1 1 0 1 1 1 0 Vps51/Vps67 ING PF12998.7 KXZ52669.1 - 0.035 14.7 1.4 0.051 14.2 1.4 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding MCPsignal PF00015.21 KXZ52669.1 - 0.035 13.9 0.6 0.047 13.5 0.6 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA2 PF16740.5 KXZ52669.1 - 0.05 13.4 4.3 0.14 12.0 3.4 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Prominin PF05478.11 KXZ52669.1 - 0.051 11.5 1.5 0.059 11.3 1.5 1.0 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 KXZ52669.1 - 0.057 13.5 6.3 0.075 13.1 6.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 KXZ52669.1 - 0.066 13.3 2.6 0.13 12.3 2.6 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 APG17 PF04108.12 KXZ52669.1 - 0.074 12.2 2.6 3.6 6.6 0.9 1.9 1 1 1 2 2 2 0 Autophagy protein Apg17 Focal_AT PF03623.13 KXZ52669.1 - 0.08 12.9 1.1 0.084 12.9 1.1 1.2 1 0 0 1 1 1 0 Focal adhesion targeting region DUF16 PF01519.16 KXZ52669.1 - 0.085 13.4 5.5 0.11 13.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Cnn_1N PF07989.11 KXZ52669.1 - 0.089 13.0 0.7 0.089 13.0 0.7 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF812 PF05667.11 KXZ52669.1 - 0.096 11.6 6.6 0.11 11.4 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Phage_Mu_Gam PF07352.12 KXZ52669.1 - 0.11 12.4 8.3 2.8 7.9 0.1 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein EMP24_GP25L PF01105.24 KXZ52669.1 - 0.11 12.4 1.1 0.13 12.1 1.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ApoLp-III PF07464.11 KXZ52669.1 - 0.11 12.6 3.8 0.32 11.1 3.8 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Syntaxin_2 PF14523.6 KXZ52669.1 - 0.12 12.8 1.8 0.3 11.5 1.8 1.7 1 1 0 1 1 1 0 Syntaxin-like protein Fib_alpha PF08702.10 KXZ52669.1 - 0.14 12.4 1.8 0.21 11.7 1.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Herpes_UL25 PF01499.16 KXZ52669.1 - 0.14 10.6 0.1 0.16 10.5 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family CREPT PF16566.5 KXZ52669.1 - 0.17 12.0 3.1 0.24 11.6 3.1 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour NEMO PF11577.8 KXZ52669.1 - 0.21 11.7 10.1 0.11 12.6 7.7 1.7 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO TMPIT PF07851.13 KXZ52669.1 - 0.23 10.7 3.6 0.29 10.3 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein AcylCoA_dehyd_C PF12186.8 KXZ52669.1 - 0.25 11.5 2.7 2 8.6 1.1 2.1 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal PEARLI-4 PF05278.12 KXZ52669.1 - 0.27 10.8 8.6 0.33 10.5 8.6 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF883 PF05957.13 KXZ52669.1 - 0.32 11.6 2.7 0.5 11.0 2.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF2730 PF10805.8 KXZ52669.1 - 0.34 11.0 4.6 5.4 7.2 4.6 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) ATG16 PF08614.11 KXZ52669.1 - 0.4 10.9 6.4 0.47 10.6 6.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YojJ PF10372.9 KXZ52669.1 - 0.41 10.8 4.5 1.7 8.8 2.3 2.5 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus YabA PF06156.13 KXZ52669.1 - 0.92 10.2 7.1 2.9 8.6 7.1 1.8 1 1 0 1 1 1 0 Initiation control protein YabA KELK PF15796.5 KXZ52669.1 - 1.5 9.4 11.1 21 5.7 11.8 2.0 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mt_ATP-synt_D PF05873.12 KXZ52669.1 - 1.8 8.4 6.8 7.4 6.4 6.8 1.8 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) ZapB PF06005.12 KXZ52669.1 - 1.8 9.1 9.4 47 4.5 9.4 2.1 1 1 0 1 1 1 0 Cell division protein ZapB FlaC_arch PF05377.11 KXZ52669.1 - 2 8.9 6.9 6.3 7.3 3.4 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Tsc35 PF15079.6 KXZ52669.1 - 2.7 7.5 13.6 26 4.3 13.6 1.9 1 1 0 1 1 1 0 Testis-specific protein 35 Ig_Tie2_1 PF10430.9 KXZ52670.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 DHODB_Fe-S_bind PF10418.9 KXZ52673.1 - 0.00045 20.0 0.8 0.0011 18.7 0.8 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B SurA_N_2 PF13623.6 KXZ52673.1 - 0.066 13.1 0.1 0.24 11.3 0.1 1.8 1 1 0 1 1 1 0 SurA N-terminal domain Condensation PF00668.20 KXZ52673.1 - 0.088 11.5 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Condensation domain FANCL_C PF11793.8 KXZ52673.1 - 0.092 12.9 2.1 0.19 11.9 2.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 KXZ52673.1 - 0.66 10.4 6.0 1.5 9.2 5.9 1.7 1 1 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 KXZ52673.1 - 0.68 10.3 6.7 1.4 9.3 3.4 2.4 2 0 0 2 2 2 0 RING-like domain DUF1336 PF07059.12 KXZ52674.1 - 1.8e-30 106.7 0.0 4.8e-20 72.6 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1336) START PF01852.19 KXZ52674.1 - 0.00055 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 START domain DUF1336 PF07059.12 KXZ52675.1 - 1.5e-13 51.3 0.0 2.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) BEX PF04538.12 KXZ52679.1 - 0.0018 18.8 0.4 0.0026 18.4 0.4 1.2 1 0 0 1 1 1 1 Brain expressed X-linked like family OmpH PF03938.14 KXZ52679.1 - 0.0089 16.4 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) FliG_N PF14842.6 KXZ52679.1 - 0.023 15.2 0.7 0.069 13.7 0.5 1.9 2 0 0 2 2 2 0 FliG N-terminal domain NPV_P10 PF05531.12 KXZ52679.1 - 0.039 14.4 0.0 0.41 11.1 0.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 KXZ52679.1 - 0.039 12.5 0.9 0.043 12.4 0.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KXZ52679.1 - 0.039 14.0 1.2 0.081 13.0 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 KXZ52679.1 - 0.041 14.1 0.9 0.07 13.4 0.9 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Peptidase_S46 PF10459.9 KXZ52679.1 - 0.043 12.5 0.3 0.054 12.1 0.3 1.2 1 0 0 1 1 1 0 Peptidase S46 Allexi_40kDa PF05549.11 KXZ52679.1 - 0.11 12.0 0.4 0.15 11.6 0.4 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DASH_Dad4 PF08650.10 KXZ52679.1 - 0.11 12.5 1.1 0.33 11.0 1.0 1.8 1 1 1 2 2 2 0 DASH complex subunit Dad4 TBK1_CCD1 PF18394.1 KXZ52679.1 - 0.16 11.5 0.9 0.57 9.7 0.3 1.5 1 1 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 Vps51 PF08700.11 KXZ52679.1 - 0.24 11.5 1.8 0.78 9.9 1.8 2.0 1 1 0 1 1 1 0 Vps51/Vps67 YabA PF06156.13 KXZ52679.1 - 0.41 11.3 2.5 0.79 10.4 2.4 1.7 1 1 0 1 1 1 0 Initiation control protein YabA CAP_N PF01213.19 KXZ52680.1 - 4 6.8 4.6 7.3 6.0 4.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SpoU_methylase PF00588.19 KXZ52683.1 - 4.1e-26 91.8 0.0 9.4e-25 87.4 0.0 2.4 1 1 0 1 1 1 1 SpoU rRNA Methylase family Fasciclin PF02469.22 KXZ52684.1 - 2.6e-29 102.0 0.0 1.4e-10 41.5 0.0 3.2 3 0 0 3 3 3 3 Fasciclin domain SASA PF03629.18 KXZ52686.1 - 5.6e-39 134.1 0.0 7.9e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase E1-E2_ATPase PF00122.20 KXZ52689.1 - 2.1e-10 40.4 0.0 9.4e-10 38.3 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase DUF3267 PF11667.8 KXZ52689.1 - 0.94 9.8 7.3 0.93 9.8 1.3 2.3 2 0 0 2 2 2 0 Putative zincin peptidase Hydrolase PF00702.26 KXZ52690.1 - 4.8e-15 56.4 0.4 0.0003 21.1 0.1 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ52690.1 - 0.028 14.5 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXZ52690.1 - 0.13 11.8 0.5 0.24 10.9 0.5 1.4 1 0 0 1 1 1 0 E1-E2 ATPase Sec6 PF06046.13 KXZ52691.1 - 2e-21 76.1 0.0 2.6e-14 52.5 0.1 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec6 SOG2 PF10428.9 KXZ52691.1 - 0.31 10.2 0.3 0.57 9.3 0.0 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein DUF789 PF05623.12 KXZ52692.1 - 3.7e-16 59.7 0.0 3.7e-12 46.5 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF789) DUF4750 PF15938.5 KXZ52694.1 - 2.3e-08 33.5 3.2 3e-08 33.2 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) DUF4191 PF13829.6 KXZ52694.1 - 0.0044 16.4 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) ER PF01133.17 KXZ52695.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Enhancer of rudimentary Vac_ImportDeg PF09783.9 KXZ52696.1 - 9.3e-37 126.3 0.0 1.2e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein 2OG-FeII_Oxy_3 PF13640.6 KXZ52696.1 - 1.7e-06 28.8 0.0 3.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXZ52698.1 - 0.05 14.5 0.0 0.16 12.9 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXZ52699.1 - 2.3e-07 31.6 0.0 4.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXZ52700.1 - 1.2e-07 32.5 0.0 2.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dynamin_N PF00350.23 KXZ52701.1 - 1.3e-13 51.4 0.0 4.2e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXZ52701.1 - 8.9e-07 29.0 0.0 0.00052 20.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.27 KXZ52701.1 - 0.00048 20.6 0.4 0.0016 19.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KXZ52701.1 - 0.0019 18.1 0.0 0.0076 16.2 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KXZ52701.1 - 0.023 14.2 0.1 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.22 KXZ52701.1 - 0.1 11.8 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Adeno_IVa2 PF02456.15 KXZ52701.1 - 0.12 11.1 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.6 KXZ52701.1 - 0.14 11.9 0.6 1 9.1 0.3 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain KxDL PF10241.9 KXZ52701.1 - 0.65 10.3 3.7 4.1 7.8 0.5 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein SDA1 PF05285.12 KXZ52701.1 - 1.2 8.5 27.1 2 7.7 27.1 1.3 1 0 0 1 1 1 0 SDA1 AAA_23 PF13476.6 KXZ52701.1 - 2.2 8.7 7.0 0.2 12.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain Syntaxin PF00804.25 KXZ52703.1 - 0.055 13.1 0.1 0.08 12.6 0.1 1.2 1 0 0 1 1 1 0 Syntaxin RHSP PF07999.11 KXZ52705.1 - 0.031 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein Arm PF00514.23 KXZ52706.1 - 0.00027 20.9 11.9 0.028 14.5 0.2 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXZ52706.1 - 0.0024 18.0 13.6 11 6.6 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat RTP1_C1 PF10363.9 KXZ52706.1 - 0.059 13.6 0.7 27 5.0 0.0 3.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 CRAL_TRIO PF00650.20 KXZ52707.1 - 8.5e-28 97.1 0.0 1.1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXZ52707.1 - 1.3e-06 28.6 0.0 1.7e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Tox-SHH PF15652.6 KXZ52707.1 - 0.1 13.6 0.0 15 6.6 0.0 2.2 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature Peptidase_M16_C PF05193.21 KXZ52708.1 - 7.6e-21 74.9 0.0 7.9e-19 68.4 0.0 3.2 3 1 0 3 3 3 1 Peptidase M16 inactive domain acVLRF1 PF18859.1 KXZ52708.1 - 0.034 14.4 1.0 0.21 11.9 0.7 2.3 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Mod_r PF07200.13 KXZ52709.1 - 0.0064 16.6 6.5 0.0064 16.6 6.5 11.2 6 3 3 10 10 10 2 Modifier of rudimentary (Mod(r)) protein MCC-bdg_PDZ PF10506.9 KXZ52709.1 - 0.011 15.7 2.9 0.011 15.7 2.9 9.0 9 2 0 9 9 9 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CCD PF07860.11 KXZ52709.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 WisP family C-Terminal Region NPV_P10 PF05531.12 KXZ52709.1 - 1.6 9.3 62.5 0.9 10.0 0.7 12.5 9 2 3 13 13 13 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 KXZ52709.1 - 2.9 7.7 91.1 0.029 14.2 1.2 12.6 5 2 5 12 12 12 0 Phage minor structural protein GP20 Serglycin PF04360.12 KXZ52709.1 - 7.3 6.5 6.6 0.69 9.8 0.5 2.3 3 0 0 3 3 3 0 Serglycin TPR_MLP1_2 PF07926.12 KXZ52710.1 - 0.023 14.8 3.8 0.023 14.8 3.8 4.9 1 1 4 5 5 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KXZ52710.1 - 0.023 15.1 38.7 0.34 11.3 15.1 3.0 1 1 2 3 3 3 0 Fez1 DUF1664 PF07889.12 KXZ52710.1 - 0.026 14.6 7.7 0.035 14.1 0.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 KXZ52710.1 - 0.034 13.9 21.5 0.051 13.3 0.3 4.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 KXZ52710.1 - 0.036 14.3 2.0 0.036 14.3 2.0 4.6 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KXZ52710.1 - 0.096 12.0 29.1 1.6 8.1 0.7 3.8 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KXZ52710.1 - 0.17 12.1 2.0 3.4 7.8 0.4 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KXZ52710.1 - 0.28 11.6 3.6 4.5 7.8 0.4 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 KXZ52710.1 - 0.48 11.0 51.8 0.32 11.5 11.7 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region FH2 PF02181.23 KXZ52710.1 - 0.99 8.5 13.6 0.4 9.7 2.1 2.7 3 1 0 3 3 3 0 Formin Homology 2 Domain CENP-F_leu_zip PF10473.9 KXZ52710.1 - 1.4 9.0 33.4 4 7.5 2.1 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KXZ52710.1 - 2.3 8.4 54.8 0.1 12.8 11.4 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) MPS2 PF17060.5 KXZ52710.1 - 4.8 6.4 10.8 4 6.6 1.9 2.8 1 1 2 3 3 3 0 Monopolar spindle protein 2 PRKG1_interact PF15898.5 KXZ52710.1 - 6.4 7.7 34.2 9.2 7.2 1.2 4.9 2 1 3 5 5 5 0 cGMP-dependent protein kinase interacting domain Bap31_Bap29_C PF18035.1 KXZ52710.1 - 6.6 6.8 11.8 9.2 6.4 0.8 4.4 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Spc7 PF08317.11 KXZ52710.1 - 7.7 5.3 42.1 2.3 7.0 6.4 3.3 1 1 3 4 4 4 0 Spc7 kinetochore protein MscS_porin PF12795.7 KXZ52710.1 - 7.9 5.9 52.9 0.22 11.1 15.8 2.6 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Prefoldin_2 PF01920.20 KXZ52710.1 - 7.9 6.5 14.1 2.9 7.9 0.1 4.0 2 1 0 4 4 4 0 Prefoldin subunit YabA PF06156.13 KXZ52710.1 - 8.4 7.1 18.3 9.9 6.9 0.5 4.2 1 1 1 3 3 3 0 Initiation control protein YabA Filament PF00038.21 KXZ52710.1 - 9.8 5.6 38.8 0.78 9.3 3.8 3.6 1 1 1 3 3 3 0 Intermediate filament protein EMP24_GP25L PF01105.24 KXZ52713.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DEAD PF00270.29 KXZ52714.1 - 1.8e-40 138.6 0.0 5.8e-40 136.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ52714.1 - 3e-26 91.9 0.0 2.3e-25 89.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ52714.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 KXZ52714.1 - 0.015 14.6 0.1 0.033 13.6 0.1 1.7 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD CMS1 PF14617.6 KXZ52714.1 - 0.13 11.6 0.2 0.36 10.1 0.0 1.8 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit MatE PF01554.18 KXZ52717.1 - 2.6e-46 157.2 27.2 1.4e-26 93.0 3.2 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KXZ52717.1 - 2e-06 28.0 9.1 2e-06 28.0 9.1 4.4 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain CAF1C_H4-bd PF12265.8 KXZ52718.1 - 1.7e-30 105.1 1.0 6.1e-30 103.3 0.7 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXZ52718.1 - 1.5e-22 79.4 10.8 7.6e-05 23.4 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ52718.1 - 1.3e-06 28.6 0.6 0.0043 17.3 0.0 3.3 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ52718.1 - 0.001 19.0 0.3 0.12 12.2 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Prefoldin PF02996.17 KXZ52719.1 - 1.7e-23 82.8 1.6 2.1e-23 82.5 1.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Serine_rich PF08824.10 KXZ52719.1 - 0.03 14.3 0.7 4.5 7.3 0.0 2.1 1 1 1 2 2 2 0 Serine rich protein interaction domain DUF1471 PF07338.13 KXZ52719.1 - 0.33 10.9 3.7 8.3 6.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) Mg_trans_NIPA PF05653.14 KXZ52720.1 - 8.5e-32 110.4 16.5 1.2e-31 110.0 16.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA TMEM252 PF15664.5 KXZ52720.1 - 0.15 11.8 0.2 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 252 family PIP5K PF01504.18 KXZ52721.1 - 1.9e-38 132.3 0.0 3.2e-29 102.0 0.0 2.5 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KXZ52721.1 - 9.5e-18 64.1 0.0 1.6e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-CCCH PF00642.24 KXZ52722.1 - 5.4e-08 32.5 1.6 8.1e-08 32.0 1.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXZ52722.1 - 0.00087 19.3 6.1 0.0013 18.7 6.1 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 KXZ52722.1 - 0.029 14.8 5.4 0.041 14.4 5.4 1.2 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KXZ52722.1 - 0.13 12.1 3.4 0.22 11.4 3.4 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger CbiA PF01656.23 KXZ52723.1 - 4.6e-25 88.1 0.0 6.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KXZ52723.1 - 2.2e-23 83.0 0.2 4.7e-23 81.9 0.2 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 KXZ52723.1 - 8.5e-19 68.1 0.1 1.8e-18 67.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KXZ52723.1 - 6.6e-11 41.9 3.2 3.3e-07 29.8 0.9 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase CBP_BcsQ PF06564.12 KXZ52723.1 - 3.6e-08 33.2 0.7 0.0029 17.1 0.4 2.1 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 KXZ52723.1 - 1.9e-07 30.6 0.0 3.3e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KXZ52723.1 - 2.6e-07 30.4 0.4 0.00022 20.8 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KXZ52723.1 - 0.00087 19.2 3.5 0.035 13.9 0.1 2.2 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 KXZ52723.1 - 0.003 17.2 0.4 0.0053 16.4 0.4 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 KXZ52723.1 - 0.004 17.0 0.1 0.0076 16.1 0.1 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Nucleotid_trans PF03407.16 KXZ52723.1 - 0.015 15.3 0.0 0.85 9.5 0.0 2.2 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase VirC1 PF07015.11 KXZ52723.1 - 0.018 14.4 0.1 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 VirC1 protein AAA_24 PF13479.6 KXZ52723.1 - 0.02 14.7 0.1 0.03 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KXZ52723.1 - 0.027 13.5 0.8 0.1 11.5 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KXZ52723.1 - 0.05 13.8 0.0 0.08 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ52723.1 - 0.22 11.1 0.8 0.53 9.8 0.8 1.7 1 1 0 1 1 1 0 AAA domain Glycos_transf_1 PF00534.20 KXZ52724.1 - 4.1e-18 65.5 0.0 7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ52724.1 - 3.8e-11 43.6 0.1 1e-10 42.2 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXZ52724.1 - 5e-05 23.6 0.0 0.00051 20.4 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ52724.1 - 0.00056 19.9 0.8 0.43 10.6 0.0 3.0 3 0 0 3 3 3 2 Glycosyltransferase Family 4 DUF1752 PF08550.10 KXZ52724.1 - 0.042 13.7 0.6 0.094 12.6 0.6 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) Ribophorin_I PF04597.14 KXZ52725.1 - 4.3e-123 411.8 2.2 5.1e-123 411.5 2.2 1.0 1 0 0 1 1 1 1 Ribophorin I Spike_NTD PF16451.5 KXZ52728.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain Lung_7-TM_R PF06814.13 KXZ52730.1 - 3.7e-51 174.1 14.9 4.6e-51 173.8 14.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 KXZ52730.1 - 0.00089 18.7 17.3 0.00089 18.7 17.3 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF3671 PF12420.8 KXZ52730.1 - 1.2 9.3 10.1 4.7 7.3 5.8 3.1 2 1 0 2 2 2 0 Protein of unknown function Peptidase_M16 PF00675.20 KXZ52732.1 - 1.2e-48 164.9 0.0 1.8e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXZ52732.1 - 1.1e-39 136.4 0.0 9.4e-38 130.1 0.0 2.6 3 0 0 3 3 3 1 Peptidase M16 inactive domain MULE PF10551.9 KXZ52732.1 - 0.074 13.5 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain MtrB PF05440.12 KXZ52732.1 - 0.13 12.7 0.1 24 5.4 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B AAA_11 PF13086.6 KXZ52733.1 - 1.6 8.4 7.4 2.3 8.0 7.4 1.1 1 0 0 1 1 1 0 AAA domain DUF4078 PF13300.6 KXZ52733.1 - 6 7.3 26.0 0.22 11.8 17.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4078) PAP_fibrillin PF04755.12 KXZ52734.1 - 4.3e-07 30.1 0.0 0.00039 20.4 0.0 3.3 3 0 0 3 3 3 2 PAP_fibrillin SesA PF17107.5 KXZ52734.1 - 0.16 12.2 0.7 0.34 11.1 0.7 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SMI1_KNR4 PF09346.10 KXZ52735.1 - 0.00081 19.8 0.0 0.0018 18.6 0.0 1.4 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Pkinase PF00069.25 KXZ52736.1 - 4.8e-11 42.5 0.0 5.7e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52736.1 - 2.3e-10 40.2 0.0 2.7e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase WHEP-TRS PF00458.20 KXZ52737.1 - 5.8e-05 23.2 1.8 9.5e-05 22.5 1.8 1.3 1 0 0 1 1 1 1 WHEP-TRS domain Pkinase_Tyr PF07714.17 KXZ52738.1 - 1.7e-17 63.6 0.0 2.1e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ52738.1 - 4.6e-15 55.7 0.0 6.5e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Aldedh PF00171.22 KXZ52739.1 - 2.4e-15 56.0 0.0 1.1e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 KXZ52740.1 - 3.3e-17 62.8 3.3 9.8e-09 34.9 0.1 3.3 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXZ52740.1 - 4.4e-06 26.8 0.2 1.5e-05 25.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ52740.1 - 3.8e-05 23.0 2.3 0.00011 21.4 2.4 1.7 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXZ52740.1 - 0.00018 20.8 0.4 0.0008 18.7 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXZ52740.1 - 0.00053 19.3 0.1 0.00053 19.3 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KXZ52740.1 - 0.0017 18.0 0.6 0.0043 16.7 0.6 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXZ52740.1 - 0.0049 16.1 0.1 0.0082 15.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KXZ52740.1 - 0.0051 16.2 0.7 0.0073 15.7 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXZ52740.1 - 0.0073 15.4 0.4 0.011 14.9 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXZ52740.1 - 0.011 14.4 0.4 0.016 13.9 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.24 KXZ52740.1 - 0.013 14.9 0.0 0.1 11.8 0.1 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXZ52740.1 - 0.018 15.6 0.2 0.018 15.6 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Erythro-docking PF09277.11 KXZ52740.1 - 0.022 14.6 0.9 0.074 13.0 0.6 1.9 2 0 0 2 2 2 0 Erythronolide synthase, docking PPE PF00823.19 KXZ52740.1 - 4.6 7.3 6.0 0.4 10.8 0.6 2.0 3 0 0 3 3 3 0 PPE family MIF4G_like_2 PF09090.11 KXZ52742.1 - 1.6e-09 37.6 0.0 9.4e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 MIF4G like MIF4G PF02854.19 KXZ52742.1 - 0.0016 18.2 0.0 0.0087 15.7 0.0 1.8 2 0 0 2 2 2 1 MIF4G domain Med3 PF11593.8 KXZ52742.1 - 1.1 8.4 6.9 1.8 7.7 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal IMS PF00817.20 KXZ52743.1 - 1.6e-33 115.8 0.1 2.7e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXZ52743.1 - 6.2e-14 52.7 0.0 1.7e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXZ52743.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif SPC25 PF06703.11 KXZ52744.1 - 1.1e-28 100.1 0.0 1.2e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3382 PF11862.8 KXZ52744.1 - 0.08 13.2 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Transgly_assoc PF04226.13 KXZ52744.1 - 0.12 12.7 2.3 0.18 12.0 2.3 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein DER1 PF04511.15 KXZ52745.1 - 4e-37 128.0 13.6 4.7e-37 127.8 13.6 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 KXZ52745.1 - 0.0012 18.8 14.6 0.0025 17.8 14.6 1.5 1 0 0 1 1 1 1 Rhomboid family DUF5562 PF17717.1 KXZ52745.1 - 0.058 13.4 1.1 0.12 12.4 1.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5562) zf-Di19 PF05605.12 KXZ52746.1 - 0.038 14.3 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXZ52746.1 - 0.2 12.6 0.1 0.36 11.8 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger TPR_1 PF00515.28 KXZ52747.1 - 4.9e-19 67.3 4.5 1.8e-08 33.8 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ52747.1 - 4.6e-18 63.8 4.6 4.9e-08 32.5 0.5 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ52747.1 - 3.5e-13 49.7 1.4 5.4e-07 29.8 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ52747.1 - 1e-12 47.2 2.7 0.00033 20.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ52747.1 - 2.1e-12 46.5 4.6 2.9e-06 26.9 0.1 4.1 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 KXZ52747.1 - 4.2e-10 40.1 3.4 2.2e-08 34.6 2.4 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ52747.1 - 5.3e-08 32.4 0.5 2.5e-05 24.0 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ52747.1 - 9e-08 32.0 2.4 0.00056 20.1 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ52747.1 - 2.5e-07 30.9 2.1 0.016 16.0 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ52747.1 - 6.3e-05 23.4 3.0 0.09 13.4 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ52747.1 - 0.00031 20.5 1.7 0.14 12.1 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ52747.1 - 0.0004 19.7 1.6 0.054 12.7 1.6 2.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ52747.1 - 0.00063 19.8 0.3 0.0049 17.0 0.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ52747.1 - 0.00078 19.9 2.7 0.0014 19.1 1.3 2.0 1 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ52747.1 - 0.003 17.7 0.5 0.61 10.4 0.2 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 EST1_DNA_bind PF10373.9 KXZ52747.1 - 0.0069 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_21 PF09976.9 KXZ52747.1 - 0.0096 15.6 2.5 0.64 9.7 0.3 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain BTAD PF03704.17 KXZ52747.1 - 0.014 15.9 1.1 1.5 9.3 0.6 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.18 KXZ52747.1 - 0.055 13.5 0.8 0.18 11.9 0.3 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 KXZ52747.1 - 0.06 12.8 0.6 17 5.0 0.0 3.5 4 0 0 4 4 4 0 SHNi-TPR PPR PF01535.20 KXZ52747.1 - 0.13 12.6 0.1 0.95 9.9 0.0 2.4 3 0 0 3 3 2 0 PPR repeat CHCH PF06747.13 KXZ52748.1 - 7.5e-05 22.8 0.1 0.00012 22.1 0.1 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KXZ52748.1 - 0.0012 18.9 0.9 0.0015 18.5 0.9 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KXZ52748.1 - 0.0085 16.1 0.3 0.013 15.5 0.0 1.5 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Hus1 PF04005.12 KXZ52749.1 - 1.7e-38 132.4 0.0 1.9e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein VHP PF02209.19 KXZ52750.1 - 2.1e-13 50.1 1.2 3.5e-13 49.4 1.2 1.4 1 0 0 1 1 1 1 Villin headpiece domain Y_phosphatase PF00102.27 KXZ52751.1 - 1.2e-66 224.6 0.3 1.7e-66 224.1 0.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXZ52751.1 - 1.1e-07 32.1 1.1 4.1e-07 30.2 0.2 2.2 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KXZ52751.1 - 4.4e-05 23.6 0.4 0.00013 22.0 0.0 1.9 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KXZ52751.1 - 0.00013 21.8 0.0 0.00046 20.0 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KXZ52751.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Rubis-subs-bind PF09273.11 KXZ52752.1 - 9.2e-10 39.3 4.2 0.00011 22.9 0.0 2.8 2 2 1 3 3 3 2 Rubisco LSMT substrate-binding SET PF00856.28 KXZ52752.1 - 1.3e-05 25.7 0.0 2.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 SET domain HAMP_N3 PF18575.1 KXZ52752.1 - 0.011 15.2 0.2 0.031 13.9 0.2 1.7 1 0 0 1 1 1 0 HAMP N-terminal domain 3 Methyltransf_16 PF10294.9 KXZ52753.1 - 3.7e-21 75.6 0.0 4.8e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXZ52753.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KXZ52753.1 - 0.023 15.4 0.2 0.045 14.5 0.1 1.7 2 1 0 2 2 2 0 Methyltransferase domain Guanylate_cyc PF00211.20 KXZ52754.1 - 8.1e-55 185.3 0.0 1.3e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Myb_CC_LHEQLE PF14379.6 KXZ52754.1 - 0.037 13.8 0.5 0.09 12.5 0.5 1.6 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Hydrolase_4 PF12146.8 KXZ52755.1 - 3.6e-12 46.1 1.2 8.7e-11 41.5 1.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ52755.1 - 1e-08 35.2 0.0 2.7e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXZ52755.1 - 1.4e-06 28.2 0.1 2.1e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KXZ52755.1 - 0.00033 21.3 24.4 0.00033 21.3 24.4 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXZ52755.1 - 0.0063 16.0 0.1 0.062 12.8 0.4 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KXZ52755.1 - 0.14 12.3 0.0 0.78 9.9 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein DUF1100 PF06500.11 KXZ52755.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 KXZ52755.1 - 0.21 10.2 0.4 12 4.5 0.1 2.3 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) SIR2 PF02146.17 KXZ52756.1 - 6.9e-33 114.0 0.0 3.5e-32 111.8 0.0 1.9 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KXZ52756.1 - 0.00057 19.6 0.0 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF364 PF04016.12 KXZ52756.1 - 0.07 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation LYTB PF02401.18 KXZ52756.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 LytB protein HAD_2 PF13419.6 KXZ52757.1 - 6.7e-08 32.8 0.0 5.5e-07 29.8 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ52757.1 - 1.5e-06 28.7 0.0 1.6e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ52757.1 - 3.6e-06 26.9 0.0 8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 KXZ52757.1 - 8e-05 22.5 0.0 0.0039 17.1 0.0 2.2 2 0 0 2 2 2 1 Acid Phosphatase SMC_N PF02463.19 KXZ52758.1 - 3.1e-08 33.3 0.1 3.3e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXZ52758.1 - 2.6e-06 27.7 0.0 0.00066 20.0 0.0 3.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain FcoT PF10862.8 KXZ52758.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 FcoT-like thioesterase domain UQ_con PF00179.26 KXZ52759.1 - 1.5e-37 128.4 0.0 1.8e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA_23 PF13476.6 KXZ52760.1 - 6.3e-14 52.9 0.0 8.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KXZ52760.1 - 5.5e-09 35.8 0.0 7.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXZ52760.1 - 2.3e-06 27.6 0.0 2.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXZ52760.1 - 4.7e-06 26.2 0.0 8.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ52760.1 - 0.00024 21.5 0.7 0.00029 21.3 0.1 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KXZ52760.1 - 0.00037 20.4 0.1 0.00051 20.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 KXZ52760.1 - 0.00045 19.9 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ52760.1 - 0.0054 17.3 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXZ52760.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KXZ52760.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KXZ52760.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 KXZ52760.1 - 0.027 15.0 0.0 0.047 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KXZ52760.1 - 0.075 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KXZ52760.1 - 0.14 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 NACHT domain DUF2813 PF11398.8 KXZ52760.1 - 0.14 11.3 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) RsgA_GTPase PF03193.16 KXZ52760.1 - 0.22 11.4 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Adeno_IVa2 PF02456.15 KXZ52760.1 - 0.28 9.9 0.0 0.4 9.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein SMC_N PF02463.19 KXZ52761.1 - 1.1e-24 87.2 0.0 2.7e-24 85.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXZ52761.1 - 3.3e-14 53.9 16.3 3.3e-14 53.9 16.3 4.9 3 2 0 3 3 1 1 AAA domain AAA_15 PF13175.6 KXZ52761.1 - 7.5e-12 45.6 0.0 4.1e-11 43.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain SMC_hinge PF06470.13 KXZ52761.1 - 3.8e-08 33.6 0.0 7.6e-07 29.5 0.0 2.9 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 KXZ52761.1 - 1.1e-05 25.1 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MukB PF04310.12 KXZ52761.1 - 0.00082 19.2 2.8 0.013 15.3 0.1 3.1 3 0 0 3 3 3 1 MukB N-terminal AAA_21 PF13304.6 KXZ52761.1 - 0.0036 17.2 0.1 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KXZ52761.1 - 0.072 12.4 0.0 0.072 12.4 0.0 3.2 4 0 0 4 4 4 0 FtsK/SpoIIIE family NACHT PF05729.12 KXZ52761.1 - 0.076 12.9 0.8 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 KXZ52761.1 - 0.31 11.5 0.0 0.31 11.5 0.0 5.7 5 2 0 5 5 4 0 ABC transporter L27_N PF09060.10 KXZ52761.1 - 0.35 11.0 4.0 6.9 6.8 0.0 3.6 3 0 0 3 3 3 0 L27_N MMR_HSR1 PF01926.23 KXZ52762.1 - 4.1e-21 75.2 0.0 6.5e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ52762.1 - 7.8e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXZ52762.1 - 0.00021 21.2 0.0 0.00088 19.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KXZ52762.1 - 0.0018 18.3 0.2 0.017 15.2 0.1 2.1 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 KXZ52762.1 - 0.0039 16.6 0.0 0.012 15.0 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KXZ52762.1 - 0.086 13.4 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 KXZ52762.1 - 0.12 12.6 0.2 0.79 10.0 0.2 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase LRR_6 PF13516.6 KXZ52763.1 - 4.4e-07 29.4 0.8 0.94 9.7 0.0 4.4 3 1 1 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KXZ52763.1 - 0.0013 19.0 0.0 0.13 12.8 0.0 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ52763.1 - 0.12 13.1 0.0 99 4.1 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat SBDS_C PF09377.10 KXZ52766.1 - 0.27 11.3 1.1 0.81 9.7 1.0 2.1 1 1 0 1 1 1 0 SBDS protein C-terminal domain Nop PF01798.18 KXZ52767.1 - 6.5e-89 297.4 0.1 1.2e-88 296.5 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXZ52767.1 - 9.2e-20 70.8 0.2 3.4e-19 69.0 0.2 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain NADH-UOR_E PF16514.5 KXZ52767.1 - 0.057 13.7 0.5 0.71 10.2 0.1 2.6 2 0 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E ApbA_C PF08546.11 KXZ52767.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal RNA_polI_A34 PF08208.11 KXZ52767.1 - 2.2 8.4 29.0 4.9 7.2 29.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 KXZ52767.1 - 3.2 5.9 11.7 5.7 5.1 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.12 KXZ52767.1 - 5.8 6.2 16.6 9 5.6 16.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.12 KXZ52767.1 - 6.3 6.5 14.9 11 5.8 14.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GCP_N_terminal PF17681.1 KXZ52768.1 - 2.7e-45 155.3 0.0 9.1e-45 153.6 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXZ52768.1 - 6.7e-38 130.9 0.0 9.9e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF5552 PF17706.1 KXZ52768.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5552) DDHD PF02862.17 KXZ52769.1 - 0.12 12.5 6.7 0.061 13.5 1.1 2.4 2 0 0 2 2 2 0 DDHD domain PH PF00169.29 KXZ52769.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 PH domain EPL1 PF10513.9 KXZ52769.1 - 3.2 8.1 19.9 0.12 12.8 3.9 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like PUB PF09409.10 KXZ52770.1 - 8.9e-11 41.6 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 PUB domain ZZ PF00569.17 KXZ52770.1 - 2e-05 24.3 0.9 2e-05 24.3 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 KXZ52770.1 - 0.54 10.6 15.4 0.44 10.9 2.3 2.7 3 0 0 3 3 3 0 C1 domain Cyto_heme_lyase PF01265.17 KXZ52772.1 - 1e-55 189.4 2.6 4.9e-55 187.2 2.6 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Aminotran_5 PF00266.19 KXZ52773.1 - 7.6e-133 443.0 0.0 8.7e-133 442.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXZ52773.1 - 4.9e-09 36.0 0.2 8e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXZ52773.1 - 2.6e-05 22.9 0.0 0.00013 20.6 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Glyco_trans_4_4 PF13579.6 KXZ52773.1 - 0.47 10.9 8.3 5.2 7.5 2.4 2.8 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain LRR_4 PF12799.7 KXZ52774.1 - 1.4e-15 57.1 11.4 0.029 14.8 0.0 10.3 8 3 4 12 12 12 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ52774.1 - 7.9e-09 35.2 11.9 0.59 9.9 0.0 9.8 10 4 1 11 11 11 3 Leucine rich repeat F-box-like PF12937.7 KXZ52774.1 - 2.1e-07 30.7 2.2 1.1e-06 28.5 0.9 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXZ52774.1 - 0.00014 21.6 2.5 0.00014 21.6 2.5 2.8 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.6 KXZ52774.1 - 0.023 14.7 15.2 28 5.1 0.1 9.4 12 0 0 12 12 12 0 Leucine Rich repeat Stanniocalcin PF03298.13 KXZ52774.1 - 0.34 10.2 1.2 0.73 9.1 0.3 1.9 2 0 0 2 2 2 0 Stanniocalcin family Metallophos PF00149.28 KXZ52775.1 - 9.6e-07 29.5 0.0 1.6e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ52775.1 - 0.00012 22.3 0.0 0.00021 21.6 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_4 PF13637.6 KXZ52776.1 - 1.1e-10 41.8 0.5 4.8 7.9 0.1 7.9 7 3 1 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ52776.1 - 5.6e-09 36.5 0.0 0.57 10.8 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ52776.1 - 4.2e-07 29.8 0.3 25 5.9 0.0 8.0 7 2 3 10 10 10 2 Ankyrin repeat Laminin_I PF06008.14 KXZ52778.1 - 0.24 11.1 1.0 0.35 10.5 1.0 1.2 1 0 0 1 1 1 0 Laminin Domain I kleA_kleC PF17383.2 KXZ52778.1 - 0.29 11.5 3.1 0.37 11.1 0.8 2.3 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A WD40 PF00400.32 KXZ52779.1 - 2.1e-35 120.1 12.6 1.2e-08 35.4 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KXZ52779.1 - 2.1e-21 76.5 0.0 6e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KXZ52779.1 - 5e-12 46.0 0.0 5.4e-05 23.4 0.0 5.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KXZ52779.1 - 0.0018 18.2 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 LisH PQQ_3 PF13570.6 KXZ52779.1 - 0.029 14.9 3.5 1.4 9.5 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Ge1_WD40 PF16529.5 KXZ52779.1 - 0.092 11.7 0.0 2.2 7.1 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rhomboid PF01694.22 KXZ52780.1 - 6.7e-25 87.8 4.7 6.7e-25 87.8 4.7 2.0 2 0 0 2 2 2 1 Rhomboid family EnY2 PF10163.9 KXZ52781.1 - 2.5e-27 95.1 0.2 3.2e-27 94.7 0.2 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 RRM_1 PF00076.22 KXZ52782.1 - 6.6e-18 64.3 0.2 9.1e-18 63.9 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXZ52782.1 - 7.4e-06 26.0 0.1 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 KXZ52782.1 - 5.8e-05 22.7 0.0 8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ52782.1 - 0.014 15.2 0.1 0.028 14.3 0.1 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXZ52782.1 - 0.018 15.0 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KXZ52782.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.6 1 1 0 1 1 1 0 RNA recognition motif 6PGD PF00393.19 KXZ52783.1 - 1.9e-124 414.8 0.0 2.3e-124 414.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXZ52783.1 - 1.8e-40 138.7 0.0 3.6e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Nif11 PF07862.11 KXZ52783.1 - 0.0047 17.2 0.2 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 Nif11 domain NAD_binding_11 PF14833.6 KXZ52783.1 - 0.054 13.7 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase HHH_9 PF17674.1 KXZ52783.1 - 0.12 13.2 0.0 4.6 8.2 0.0 2.8 2 0 0 2 2 2 0 HHH domain Helicase_C PF00271.31 KXZ52784.1 - 7.5e-28 97.1 0.0 1.2e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ52784.1 - 4e-17 62.5 0.0 6.2e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Translin PF01997.16 KXZ52785.1 - 6.3e-27 94.9 0.4 8.7e-26 91.2 0.4 2.1 1 1 0 1 1 1 1 Translin family DUF1839 PF08893.10 KXZ52785.1 - 0.12 11.6 0.3 0.96 8.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1839) Dynein_light PF01221.18 KXZ52786.1 - 4e-27 94.3 0.4 5e-27 94.0 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 KXZ52786.1 - 0.056 14.1 0.0 0.078 13.6 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain Spc42p PF11544.8 KXZ52786.1 - 0.091 12.8 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body component Spc42p F420_ligase PF01996.16 KXZ52786.1 - 0.099 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase Tctex-1 PF03645.13 KXZ52787.1 - 3.4e-27 94.7 0.7 4.2e-27 94.4 0.7 1.1 1 0 0 1 1 1 1 Tctex-1 family Troponin PF00992.20 KXZ52787.1 - 0.018 15.3 0.5 0.023 15.0 0.5 1.1 1 0 0 1 1 1 0 Troponin Guanylate_cyc PF00211.20 KXZ52788.1 - 1.8e-19 70.1 0.0 2.7e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Acetyltransf_1 PF00583.25 KXZ52789.1 - 0.0066 16.7 0.0 0.0084 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ52789.1 - 0.055 13.4 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3095 PF11294.8 KXZ52789.1 - 0.19 10.7 0.1 0.27 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) ABC_tran PF00005.27 KXZ52790.1 - 1.9e-22 80.3 0.3 8.2e-22 78.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter EF-hand_7 PF13499.6 KXZ52790.1 - 1.5e-05 25.4 1.1 3.5e-05 24.2 1.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair SMC_N PF02463.19 KXZ52790.1 - 0.0033 16.9 0.2 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ52790.1 - 0.052 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXZ52790.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase EF-hand_1 PF00036.32 KXZ52790.1 - 0.073 12.6 2.1 2.5 7.9 0.3 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KXZ52790.1 - 0.15 12.0 2.8 1.7 8.8 0.4 3.0 3 0 0 3 3 3 0 EF-hand domain AAA_21 PF13304.6 KXZ52790.1 - 0.78 9.5 4.5 16 5.2 0.3 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXZ52790.1 - 1.7 8.7 8.0 1.4 8.9 1.5 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 KXZ52790.1 - 4.1 6.4 15.5 5.9 5.9 14.9 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein CRAL_TRIO PF00650.20 KXZ52791.1 - 6.1e-34 117.0 0.7 1.9e-33 115.5 0.2 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXZ52791.1 - 0.0001 22.4 1.2 0.00033 20.8 1.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Snapin_Pallidin PF14712.6 KXZ52791.1 - 0.28 11.6 4.7 0.61 10.5 4.7 1.6 1 0 0 1 1 1 0 Snapin/Pallidin SKA2 PF16740.5 KXZ52791.1 - 7.9 6.3 10.0 5.8 6.7 1.3 2.7 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF478 PF04334.12 KXZ52792.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF478) Pkinase PF00069.25 KXZ52793.1 - 2.2e-61 207.5 0.0 2.9e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52793.1 - 1.2e-19 70.6 0.0 1.7e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 KXZ52793.1 - 4.8e-07 30.1 0.0 0.003 18.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ52793.1 - 2.1e-06 26.9 0.3 0.0003 20.1 0.0 3.4 3 0 0 3 3 3 1 EF hand RINGv PF12906.7 KXZ52793.1 - 1.1e-05 25.4 5.6 2.3e-05 24.4 5.6 1.5 1 0 0 1 1 1 1 RING-variant domain EF-hand_6 PF13405.6 KXZ52793.1 - 0.00014 21.5 2.5 0.0007 19.3 0.0 3.5 6 0 0 6 6 6 1 EF-hand domain EF-hand_8 PF13833.6 KXZ52793.1 - 0.00018 21.3 0.5 1.2 9.1 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain pair Pkinase_fungal PF17667.1 KXZ52793.1 - 0.00056 18.8 0.0 0.00086 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_5 PF13202.6 KXZ52793.1 - 0.0015 17.9 0.5 0.0038 16.6 0.0 1.9 2 0 0 2 2 2 1 EF hand APH PF01636.23 KXZ52793.1 - 0.025 14.5 0.3 0.025 14.5 0.3 3.2 2 2 1 3 3 3 0 Phosphotransferase enzyme family WW PF00397.26 KXZ52794.1 - 3.2e-19 68.7 10.4 3.6e-10 39.7 0.7 2.5 2 0 0 2 2 2 2 WW domain WD40 PF00400.32 KXZ52796.1 - 7.6e-49 162.7 14.8 4.9e-09 36.7 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ52796.1 - 1.8e-25 89.0 2.1 2.1e-06 27.9 0.1 6.6 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KXZ52796.1 - 4e-09 36.1 0.1 7.9e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KXZ52796.1 - 3e-07 30.5 0.0 0.026 14.4 0.0 3.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXZ52796.1 - 0.00041 19.8 0.0 1.7 7.9 0.0 3.1 2 1 1 4 4 4 2 WD40-like domain Coatomer_WDAD PF04053.14 KXZ52796.1 - 0.0017 17.5 0.4 0.4 9.7 0.0 3.3 3 1 1 4 4 4 1 Coatomer WD associated region Proteasome_A_N PF10584.9 KXZ52796.1 - 0.0043 16.7 0.1 1.2 8.9 0.0 3.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature SOBP PF15279.6 KXZ52796.1 - 0.0089 16.7 6.1 0.013 16.1 6.1 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein IKI3 PF04762.12 KXZ52796.1 - 0.0093 14.0 0.1 0.086 10.8 0.1 2.3 1 1 0 2 2 2 1 IKI3 family MORN_2 PF07661.13 KXZ52796.1 - 0.084 13.1 0.0 29 5.3 0.0 3.1 2 1 0 2 2 2 0 MORN repeat variant RTX PF02382.15 KXZ52796.1 - 0.12 12.0 6.7 0.2 11.3 6.7 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein Paf1 PF03985.13 KXZ52796.1 - 0.59 9.1 10.5 0.82 8.6 10.5 1.1 1 0 0 1 1 1 0 Paf1 SOG2 PF10428.9 KXZ52796.1 - 2.5 7.2 7.3 3.2 6.8 7.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NACHT_N PF17100.5 KXZ52796.1 - 3.2 7.5 8.4 5.6 6.8 8.4 1.3 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase DUF4366 PF14283.6 KXZ52796.1 - 4 7.5 5.7 7.5 6.6 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CPSF100_C PF13299.6 KXZ52796.1 - 4.6 7.4 8.1 8.3 6.6 8.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Rrp15p PF07890.12 KXZ52796.1 - 4.7 7.6 16.9 8.7 6.7 16.9 1.4 1 0 0 1 1 1 0 Rrp15p Presenilin PF01080.17 KXZ52796.1 - 6.5 5.4 6.0 8.8 5.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin BAF1_ABF1 PF04684.13 KXZ52796.1 - 7.7 5.4 9.2 11 4.9 9.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EF-hand_1 PF00036.32 KXZ52797.1 - 1.1e-29 99.7 5.5 5.8e-08 31.7 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KXZ52797.1 - 1.2e-26 90.3 3.7 3.1e-06 26.7 0.0 4.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KXZ52797.1 - 1.2e-23 81.5 5.9 2.3e-06 26.8 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KXZ52797.1 - 4.7e-23 81.4 4.1 2.1e-11 44.1 0.3 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXZ52797.1 - 9.9e-19 66.9 1.8 6.9e-05 22.6 0.1 4.5 5 0 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXZ52797.1 - 2.1e-07 31.3 0.0 0.0018 18.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KXZ52797.1 - 1.3e-06 28.6 0.4 0.0017 18.6 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXZ52797.1 - 0.00015 21.7 0.7 0.012 15.6 0.0 2.8 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KXZ52797.1 - 0.0099 15.8 0.5 18 5.2 0.0 3.6 2 2 1 4 4 4 0 Caleosin related protein EF-hand_10 PF14788.6 KXZ52797.1 - 0.061 13.2 1.0 7.7 6.5 0.1 3.4 4 0 0 4 4 4 0 EF hand Dna2 PF08696.11 KXZ52798.1 - 7.6e-46 156.5 0.0 1.1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KXZ52798.1 - 2e-44 151.6 0.0 3e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ52798.1 - 5e-27 95.3 0.4 2.2e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXZ52798.1 - 5.2e-12 45.9 0.5 2.4e-11 43.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXZ52798.1 - 2.8e-10 40.7 0.0 8.4e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KXZ52798.1 - 1.4e-07 31.7 0.0 9.6e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 KXZ52798.1 - 1.1e-05 25.4 0.5 0.095 12.6 0.1 2.4 2 0 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 KXZ52798.1 - 0.00015 21.6 0.0 1.4 8.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXZ52798.1 - 0.0013 18.3 0.1 0.002 17.7 0.1 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KXZ52798.1 - 0.015 15.2 0.1 0.039 13.8 0.1 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain cobW PF02492.19 KXZ52798.1 - 0.019 14.6 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Phage_SSB PF16773.5 KXZ52798.1 - 0.026 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein AAA_16 PF13191.6 KXZ52798.1 - 0.034 14.5 0.2 0.22 11.9 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KXZ52798.1 - 0.12 12.8 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) OST3_OST6 PF04756.13 KXZ52799.1 - 4.7e-12 45.9 0.4 5.4e-12 45.7 0.4 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Peptidase_M14 PF00246.24 KXZ52800.1 - 7.6e-14 52.2 0.0 1.3e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KXZ52800.1 - 2e-08 34.5 0.1 3.4e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 KXZ52800.1 - 2.5e-06 26.8 0.0 4.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_16 PF13432.6 KXZ52800.1 - 0.00046 20.8 2.6 0.0006 20.4 0.7 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ52800.1 - 0.049 13.5 1.6 9.2 6.3 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ52800.1 - 0.058 14.1 0.5 0.23 12.2 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ52800.1 - 0.082 13.1 2.0 2.4 8.5 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ52800.1 - 2 9.4 5.1 33 5.7 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat CBS PF00571.28 KXZ52801.1 - 1.2e-26 92.9 1.1 9e-11 42.1 0.0 4.6 5 0 0 5 5 5 4 CBS domain Glyco_tran_28_C PF04101.16 KXZ52802.1 - 2.9e-29 102.2 0.0 4.2e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 KXZ52802.1 - 4e-08 33.4 0.2 1e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain RAP PF08373.10 KXZ52803.1 - 3.9e-08 33.3 0.0 7.9e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 RAP domain FAST_1 PF06743.15 KXZ52803.1 - 0.001 18.9 0.9 30 4.7 0.0 5.7 3 1 4 7 7 7 2 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 KXZ52803.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 REase_MTES_1575 Rep_fac_C PF08542.11 KXZ52805.1 - 9e-19 67.7 0.0 2.1e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXZ52805.1 - 6.3e-17 62.2 0.0 1.1e-16 61.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXZ52805.1 - 1.4e-13 50.9 0.0 8.5e-10 38.6 0.0 2.9 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KXZ52805.1 - 6.7e-12 45.7 0.0 7.2e-11 42.3 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KXZ52805.1 - 1.5e-05 25.5 0.0 2.9e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXZ52805.1 - 3.9e-05 23.4 0.1 0.0001 22.1 0.1 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KXZ52805.1 - 4.1e-05 23.5 0.1 0.00014 21.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 KXZ52805.1 - 0.0001 22.2 0.0 0.00032 20.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ52805.1 - 0.00021 21.3 0.1 0.0056 16.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXZ52805.1 - 0.00021 20.5 0.0 0.00033 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KXZ52805.1 - 0.00027 20.9 0.0 0.00084 19.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KXZ52805.1 - 0.00035 20.9 0.3 0.0079 16.5 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ52805.1 - 0.00099 18.9 0.0 0.0026 17.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 KXZ52805.1 - 0.0016 18.5 0.0 0.13 12.3 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXZ52805.1 - 0.0021 18.4 0.2 0.042 14.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KXZ52805.1 - 0.0044 16.8 0.1 0.011 15.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXZ52805.1 - 0.0044 16.5 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXZ52805.1 - 0.0087 15.8 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 KXZ52805.1 - 0.011 15.2 0.1 0.11 11.9 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 KXZ52805.1 - 0.011 16.3 0.0 0.032 14.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain DEAD PF00270.29 KXZ52805.1 - 0.031 14.0 0.2 0.49 10.1 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 KXZ52805.1 - 0.055 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_assoc_2 PF16193.5 KXZ52805.1 - 0.059 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain Sigma54_activat PF00158.26 KXZ52805.1 - 0.068 12.9 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM PF00493.23 KXZ52805.1 - 0.069 12.2 0.1 0.24 10.5 0.0 1.8 2 1 0 2 2 2 0 MCM P-loop domain AAA_25 PF13481.6 KXZ52805.1 - 0.072 12.7 0.7 0.28 10.7 0.0 2.3 2 1 1 3 3 3 0 AAA domain ATPase_2 PF01637.18 KXZ52805.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 KXZ52805.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 KXZ52805.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KNTase_C PF07827.11 KXZ52805.1 - 0.15 11.9 0.0 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 KNTase C-terminal domain Mg_chelatase PF01078.21 KXZ52805.1 - 0.16 11.4 0.0 0.64 9.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PcrB PF01884.17 KXZ52806.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 PcrB family PhosphMutase PF10143.9 KXZ52807.1 - 2.1e-50 170.9 0.0 3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 KXZ52807.1 - 3e-22 79.2 0.0 2.1e-21 76.4 0.0 1.9 1 1 0 1 1 1 1 Metalloenzyme superfamily Usp PF00582.26 KXZ52809.1 - 0.00085 19.8 1.7 4.2 7.9 0.0 4.2 3 1 0 3 3 3 2 Universal stress protein family zf-RanBP PF00641.18 KXZ52810.1 - 0.0044 16.3 4.2 0.012 14.9 4.2 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C2H2_4 PF13894.6 KXZ52810.1 - 0.09 13.7 0.5 0.09 13.7 0.5 6.3 6 2 1 7 7 7 0 C2H2-type zinc finger RCC1 PF00415.18 KXZ52811.1 - 1.5e-24 86.4 2.2 1e-06 29.3 0.0 3.5 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ52811.1 - 2.5e-12 46.3 7.7 3.7e-07 29.8 1.8 2.4 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 KXZ52811.1 - 0.043 13.7 0.5 0.095 12.6 0.1 1.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KXZ52811.1 - 0.047 13.6 0.1 0.092 12.7 0.1 1.5 1 0 0 1 1 1 0 F-box-like Elongin_A PF06881.11 KXZ52811.1 - 0.053 14.1 0.2 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A FAD_binding_2 PF00890.24 KXZ52812.1 - 2e-94 317.0 6.7 2.7e-94 316.6 6.7 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXZ52812.1 - 2.6e-13 50.1 0.0 4.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 KXZ52812.1 - 1.1e-08 35.1 1.5 2.1e-08 34.1 1.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ52812.1 - 0.00087 18.6 0.2 0.098 11.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NUDIX PF00293.28 KXZ52813.1 - 1.6e-13 50.9 0.4 2.2e-13 50.4 0.4 1.2 1 0 0 1 1 1 1 NUDIX domain CAAD PF14159.6 KXZ52814.1 - 1.3e-18 66.6 0.0 2e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase LRR_6 PF13516.6 KXZ52815.1 - 6.4e-09 35.2 1.6 0.38 10.9 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KXZ52815.1 - 7.8e-06 25.7 0.6 29 5.8 0.0 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 KXZ52815.1 - 0.001 19.4 5.8 0.77 10.3 0.0 4.1 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ52815.1 - 0.0048 16.6 1.0 9.3 6.1 0.1 4.1 4 0 0 4 4 4 1 Leucine rich repeat Steroid_dh PF02544.16 KXZ52816.1 - 2.6e-14 53.5 0.0 4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Steroid_dh PF02544.16 KXZ52817.1 - 7.6e-27 94.1 0.1 8.6e-27 94.0 0.1 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase BLOC1S3 PF15753.5 KXZ52819.1 - 0.13 12.4 4.6 0.18 12.0 4.6 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Trp_syntA PF00290.20 KXZ52820.1 - 5e-92 307.4 0.0 5.8e-92 307.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 KXZ52820.1 - 2.7e-06 27.0 0.0 4.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 KXZ52820.1 - 0.00099 18.5 0.1 0.0027 17.0 0.0 1.7 2 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG PcrB PF01884.17 KXZ52820.1 - 0.0027 17.2 0.1 0.0087 15.5 0.1 1.8 2 0 0 2 2 2 1 PcrB family NanE PF04131.14 KXZ52820.1 - 0.011 14.9 0.1 0.068 12.4 0.0 2.1 1 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Pterin_bind PF00809.22 KXZ52820.1 - 0.014 15.1 0.0 0.074 12.7 0.0 2.0 1 1 1 2 2 2 0 Pterin binding enzyme FMN_dh PF01070.18 KXZ52820.1 - 0.025 13.6 0.3 0.078 12.0 0.3 1.8 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Spore_YtrH PF14034.6 KXZ52820.1 - 0.049 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Sporulation protein YtrH Radical_SAM PF04055.21 KXZ52820.1 - 0.11 12.8 0.0 0.75 10.1 0.0 2.1 1 1 1 2 2 2 0 Radical SAM superfamily Ribosomal_L11_N PF03946.14 KXZ52821.1 - 7.8e-22 76.9 0.2 1.2e-21 76.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXZ52821.1 - 6e-17 61.9 1.5 8.7e-17 61.4 0.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Thioredoxin PF00085.20 KXZ52823.1 - 5e-10 39.3 0.0 7.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KXZ52823.1 - 0.0091 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin UPF0113_N PF17833.1 KXZ52824.1 - 1.9e-31 108.5 0.8 2.8e-31 107.9 0.8 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KXZ52824.1 - 1.3e-23 83.0 0.0 2.6e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain Clavanin PF05452.11 KXZ52824.1 - 0.15 12.3 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Clavanin CPL PF08144.11 KXZ52825.1 - 3.6e-09 37.1 0.0 1.4e-05 25.4 0.0 5.2 3 2 2 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 KXZ52825.1 - 1.6e-07 30.7 0.0 0.047 13.4 0.0 3.5 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat Calmodulin_bind PF07887.11 KXZ52828.1 - 8.9e-07 28.5 0.1 1.3e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Calmodulin binding protein-like ATP-synt_C PF00137.21 KXZ52829.1 - 7.8e-26 90.2 32.4 1e-15 57.8 12.9 2.3 2 0 0 2 2 2 2 ATP synthase subunit C UPF0182 PF03699.13 KXZ52829.1 - 0.37 8.9 3.9 0.36 8.9 3.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) MotA_ExbB PF01618.16 KXZ52829.1 - 5.4 6.8 7.5 11 5.7 1.7 2.3 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family PP2C PF00481.21 KXZ52830.1 - 1.1e-64 218.6 0.0 1.2e-64 218.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXZ52830.1 - 0.00047 20.1 0.4 0.0055 16.6 0.4 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXZ52830.1 - 0.00055 19.6 0.3 0.0015 18.2 0.3 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF4298 PF14131.6 KXZ52830.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) zf-CCHC_3 PF13917.6 KXZ52831.1 - 7.1e-18 64.3 4.1 1.3e-17 63.4 4.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Peptidase_M43 PF05572.13 KXZ52831.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A BUD22 PF09073.10 KXZ52831.1 - 1 8.6 36.1 1.4 8.1 36.1 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 KXZ52831.1 - 3.4 6.1 28.7 4.8 5.6 28.7 1.1 1 0 0 1 1 1 0 Macoilin family Borrelia_P83 PF05262.11 KXZ52832.1 - 0.084 11.3 7.6 0.12 10.9 7.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.9 KXZ52832.1 - 0.54 8.5 22.5 21 3.2 22.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 KXZ52832.1 - 1.7 7.2 12.7 2.3 6.8 12.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.13 KXZ52832.1 - 3 6.8 11.6 3.8 6.4 11.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 KXZ52832.1 - 4.3 7.2 26.9 7.4 6.5 26.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 KXZ52832.1 - 8.9 6.2 16.6 1.8e+02 1.9 0.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Gly_transf_sug PF04488.15 KXZ52833.1 - 1.7e-10 41.4 0.0 2.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Met_10 PF02475.16 KXZ52833.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KXZ52833.1 - 0.11 13.2 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXZ52833.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 KXZ52833.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AAA_11 PF13086.6 KXZ52834.1 - 1.2e-11 45.0 0.0 1.8e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ52834.1 - 0.00034 21.0 0.3 0.00075 19.9 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ52834.1 - 0.036 14.5 2.8 0.16 12.4 2.8 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXZ52834.1 - 0.062 13.6 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ52834.1 - 0.09 13.2 0.3 0.17 12.3 0.3 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXZ52834.1 - 0.1 11.9 0.2 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_12 PF13087.6 KXZ52835.1 - 4e-45 153.9 0.0 2.3e-44 151.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXZ52835.1 - 3.5e-16 59.8 0.2 1.6e-14 54.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXZ52835.1 - 2.6e-09 37.6 0.0 0.054 13.8 0.0 3.6 3 0 0 3 3 3 3 AAA domain UvrD_C_2 PF13538.6 KXZ52835.1 - 1.7e-08 34.1 2.4 0.097 12.5 0.0 4.6 5 0 0 5 5 5 3 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXZ52835.1 - 1.1e-07 31.7 0.0 0.00021 20.9 0.0 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 KXZ52835.1 - 0.00014 21.6 3.2 0.044 13.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 KXZ52835.1 - 0.0018 18.1 0.0 4.5 6.9 0.0 3.8 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 KXZ52835.1 - 0.009 15.4 0.0 0.027 13.8 0.0 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KXZ52835.1 - 0.014 15.8 0.3 0.014 15.8 0.3 4.7 4 0 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 KXZ52835.1 - 0.02 15.2 0.0 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KXZ52835.1 - 0.096 12.1 0.0 53 3.2 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein Exo_endo_phos PF03372.23 KXZ52837.1 - 0.00026 20.6 0.6 0.00034 20.2 0.6 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 KXZ52838.1 - 2.3e-10 40.4 0.2 8.3e-10 38.6 0.2 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hydrolase_4 PF12146.8 KXZ52840.1 - 8.6e-11 41.6 0.0 2.7e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ52840.1 - 7.7e-10 39.7 6.7 7.7e-10 39.7 6.7 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family DAGAT PF03982.13 KXZ52840.1 - 4.5e-07 29.1 0.0 6.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Abhydrolase_1 PF00561.20 KXZ52840.1 - 9.9e-07 28.7 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 KXZ52840.1 - 3.3e-05 24.1 0.0 7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 KXZ52840.1 - 5e-05 23.3 0.0 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) BAAT_C PF08840.11 KXZ52840.1 - 8.8e-05 22.5 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KXZ52840.1 - 0.0038 17.1 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Paf1 PF03985.13 KXZ52842.1 - 1.1e-36 126.8 0.8 1.1e-35 123.4 0.8 2.2 1 1 0 1 1 1 1 Paf1 ADIP PF11559.8 KXZ52843.1 - 0.0013 18.9 17.3 0.029 14.5 3.1 2.5 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding DHC_N1 PF08385.12 KXZ52843.1 - 0.0091 14.7 1.7 0.0091 14.7 1.7 1.7 1 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 NPV_P10 PF05531.12 KXZ52843.1 - 0.012 16.0 15.7 0.92 10.0 4.7 4.1 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 KXZ52843.1 - 0.021 15.4 15.2 0.71 10.5 1.7 4.0 1 1 3 4 4 4 0 SlyX Filament PF00038.21 KXZ52843.1 - 0.022 14.3 11.6 0.031 13.9 11.6 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF1664 PF07889.12 KXZ52843.1 - 0.024 14.7 12.7 0.18 11.8 0.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KXZ52843.1 - 0.045 14.1 11.7 3 8.3 0.3 4.4 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) UBN_AB PF14075.6 KXZ52843.1 - 0.051 13.3 6.1 0.037 13.8 2.8 2.0 1 1 1 2 2 2 0 Ubinuclein conserved middle domain TMF_TATA_bd PF12325.8 KXZ52843.1 - 0.056 13.7 15.1 0.57 10.4 3.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PI3K_P85_iSH2 PF16454.5 KXZ52843.1 - 0.062 12.9 6.9 0.12 11.9 0.4 2.5 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain XhlA PF10779.9 KXZ52843.1 - 0.078 13.2 9.3 0.43 10.8 0.8 3.2 3 1 1 4 4 3 0 Haemolysin XhlA CENP-F_leu_zip PF10473.9 KXZ52843.1 - 0.13 12.3 16.2 1.4 8.9 3.4 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 KXZ52843.1 - 0.13 12.5 16.2 0.25 11.6 2.2 3.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Cep57_MT_bd PF06657.13 KXZ52843.1 - 0.15 12.5 13.0 0.076 13.5 1.7 3.1 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 GIT_CC PF16559.5 KXZ52843.1 - 0.15 11.9 15.0 2.7 7.9 1.6 4.0 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor FapA PF03961.13 KXZ52843.1 - 0.16 10.5 6.6 1.6 7.3 2.9 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A LidA_Long_CC PF18641.1 KXZ52843.1 - 0.18 11.9 10.9 1.3 9.0 1.2 2.4 1 1 0 2 2 2 0 LidA long coiled-coil domain HrpB7 PF09486.10 KXZ52843.1 - 0.18 12.2 17.3 0.11 12.9 8.1 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 KXZ52843.1 - 0.18 11.9 11.8 1 9.5 4.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 KXZ52843.1 - 0.21 11.7 14.5 0.31 11.2 1.5 2.7 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family IFT57 PF10498.9 KXZ52843.1 - 0.21 10.5 12.8 0.47 9.4 7.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 KXZ52843.1 - 0.26 10.6 13.3 1.3 8.3 9.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4279 PF14106.6 KXZ52843.1 - 0.26 11.5 3.5 5.2 7.3 0.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) betaPIX_CC PF16523.5 KXZ52843.1 - 0.27 11.1 4.2 2.5 8.0 0.8 2.6 2 2 0 2 2 2 0 betaPIX coiled coil DUF4795 PF16043.5 KXZ52843.1 - 0.36 10.4 15.6 0.32 10.5 4.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 KXZ52843.1 - 0.39 11.2 13.1 3.1 8.3 1.4 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF724 PF05266.14 KXZ52843.1 - 0.41 10.4 12.5 0.14 12.0 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IHO1 PF15771.5 KXZ52843.1 - 0.44 9.3 13.6 0.017 13.9 4.7 2.0 1 1 1 2 2 2 0 Interactor of HORMAD1 protein 1 TMPIT PF07851.13 KXZ52843.1 - 0.44 9.7 11.3 1.5 8.0 2.7 2.0 1 1 0 2 2 2 0 TMPIT-like protein TTKRSYEDQ PF10212.9 KXZ52843.1 - 0.59 9.1 14.4 1.6 7.6 14.4 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.9 KXZ52843.1 - 0.72 8.9 11.5 1.7 7.6 11.5 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SYCE1 PF15233.6 KXZ52843.1 - 0.76 9.8 13.7 0.88 9.6 9.2 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Uso1_p115_C PF04871.13 KXZ52843.1 - 0.88 10.0 17.2 7.7 6.9 5.6 2.6 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 KXZ52843.1 - 0.89 10.2 11.8 0.2 12.3 3.0 3.0 1 1 2 3 3 3 0 Initiation control protein YabA YkyA PF10368.9 KXZ52843.1 - 0.93 9.1 7.5 2.2 7.9 4.7 2.0 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Spc7 PF08317.11 KXZ52843.1 - 0.98 8.2 15.7 5.1 5.9 15.6 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 KXZ52843.1 - 1.1 8.8 18.5 1.4 8.5 7.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 HeLo PF14479.6 KXZ52843.1 - 1.4 8.7 10.5 1.9 8.3 10.5 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation GAS PF13851.6 KXZ52843.1 - 1.4 8.2 15.3 0.5 9.7 2.7 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 KXZ52843.1 - 1.5 9.0 10.4 1 9.6 0.1 3.5 3 1 0 4 4 4 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 KXZ52843.1 - 1.5 9.3 11.7 1.5 9.3 2.5 3.8 1 1 2 3 3 3 0 Cell division protein ZapB Vps53_N PF04100.12 KXZ52843.1 - 1.6 7.6 10.8 2.2 7.1 4.0 2.1 1 1 1 2 2 2 0 Vps53-like, N-terminal Fez1 PF06818.15 KXZ52843.1 - 1.7 9.0 15.6 19 5.6 15.6 2.0 1 1 0 1 1 1 0 Fez1 ATG16 PF08614.11 KXZ52843.1 - 2.1 8.5 22.9 21 5.3 16.3 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIVA PF05103.13 KXZ52843.1 - 2.5 8.2 12.3 3.3 7.8 2.8 2.5 1 1 1 2 2 2 0 DivIVA protein Rx_N PF18052.1 KXZ52843.1 - 3.1 8.1 9.3 32 4.9 4.8 3.3 1 1 2 3 3 3 0 Rx N-terminal domain PRKG1_interact PF15898.5 KXZ52843.1 - 4.3 8.3 17.0 0.41 11.6 4.3 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain HemX PF04375.14 KXZ52843.1 - 4.3 6.5 17.8 7.7 5.7 6.3 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase CENP-H PF05837.12 KXZ52843.1 - 4.7 7.7 15.0 1.9 8.9 0.3 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) YlbD_coat PF14071.6 KXZ52843.1 - 5.9 7.2 7.4 9.3 6.5 0.7 2.3 1 1 1 2 2 2 0 Putative coat protein DUF2408 PF10303.9 KXZ52843.1 - 6.2 7.4 10.5 2.6 8.6 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Prominin PF05478.11 KXZ52843.1 - 8.8 4.1 11.7 17 3.2 9.1 1.5 1 1 0 1 1 1 0 Prominin Aldedh PF00171.22 KXZ52844.1 - 4.5e-31 107.9 0.0 4.7e-26 91.3 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L4 PF00573.22 KXZ52845.1 - 2.2e-47 161.2 0.0 3.2e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ShK PF01549.24 KXZ52846.1 - 1.1e-07 32.3 10.9 3.3e-07 30.7 10.9 1.9 1 0 0 1 1 1 1 ShK domain-like Glyco_transf_21 PF13506.6 KXZ52846.1 - 0.0027 17.2 0.0 0.065 12.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KXZ52846.1 - 0.045 14.3 0.2 10 6.7 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 KXZ52846.1 - 0.046 13.5 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 TnpW PF14202.6 KXZ52846.1 - 0.25 11.2 0.5 0.53 10.1 0.5 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpW Clat_adaptor_s PF01217.20 KXZ52847.1 - 1.1e-23 83.7 0.4 1.3e-23 83.5 0.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RL10P_insert PF17777.1 KXZ52848.1 - 1.7e-22 79.2 0.2 2.9e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KXZ52848.1 - 1.1e-19 70.4 0.3 2.4e-19 69.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KXZ52848.1 - 2.6e-18 66.4 3.0 2.6e-18 66.4 3.0 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein HEAT PF02985.22 KXZ52849.1 - 1.2e-18 65.6 25.4 0.0055 16.9 0.4 9.2 10 0 0 10 10 10 6 HEAT repeat HEAT_EZ PF13513.6 KXZ52849.1 - 4.4e-15 55.8 41.0 3e-09 37.2 0.2 11.4 12 1 2 14 14 13 4 HEAT-like repeat HEAT_2 PF13646.6 KXZ52849.1 - 2.5e-10 40.6 20.6 0.0027 18.1 0.6 7.6 4 4 4 8 8 8 5 HEAT repeats Cnd1 PF12717.7 KXZ52849.1 - 2.6e-08 34.1 0.0 2.6 8.1 0.0 4.8 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXZ52849.1 - 4.3e-06 27.2 0.0 0.15 12.7 0.0 5.1 3 2 2 5 5 5 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 KXZ52849.1 - 8.8e-06 25.6 0.0 2.8e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 KXZ52849.1 - 0.0048 15.5 0.0 1.7 7.1 0.0 3.4 3 2 0 3 3 3 1 Adaptin N terminal region Arm PF00514.23 KXZ52849.1 - 0.0066 16.5 8.8 0.29 11.2 0.3 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KXZ52849.1 - 0.021 14.4 0.0 2.3 7.7 0.0 3.4 3 1 0 3 3 3 0 CLASP N terminal RIX1 PF08167.12 KXZ52849.1 - 0.04 13.6 0.0 1.1e+02 2.5 0.0 4.5 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Dopey_N PF04118.14 KXZ52849.1 - 0.084 12.0 0.0 1.2 8.2 0.0 2.9 4 0 0 4 4 4 0 Dopey, N-terminal TAF6_C PF07571.13 KXZ52849.1 - 0.13 12.6 0.0 2.1 8.8 0.0 2.8 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain YqfQ PF14181.6 KXZ52849.1 - 4.9 7.3 5.1 66 3.6 0.0 2.3 2 0 0 2 2 2 0 YqfQ-like protein Tub PF01167.18 KXZ52850.1 - 8e-92 307.3 0.0 9.5e-92 307.1 0.0 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 KXZ52850.1 - 0.00026 20.7 0.1 0.0014 18.3 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3527) SpoU_sub_bind PF08032.12 KXZ52850.1 - 0.036 14.3 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding WD40 PF00400.32 KXZ52851.1 - 3.7e-15 56.0 0.7 0.0062 17.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ52851.1 - 9.7e-05 22.6 0.1 0.27 11.5 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L21p PF00829.21 KXZ52851.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein zf-Dof PF02701.15 KXZ52853.1 - 1.3e-28 98.9 10.2 2.1e-28 98.2 10.2 1.3 1 0 0 1 1 1 1 Dof domain, zinc finger RFC1 PF08519.12 KXZ52854.1 - 4.3e-46 156.9 0.0 6.6e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KXZ52854.1 - 9.7e-12 45.1 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KXZ52854.1 - 2.9e-11 43.9 0.0 7.3e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXZ52854.1 - 1.4e-06 28.3 0.0 1.9e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KXZ52854.1 - 4.6e-05 23.3 0.0 7.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 KXZ52854.1 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ52854.1 - 0.0016 18.7 0.0 0.0045 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain YL1 PF05764.13 KXZ52854.1 - 0.0018 18.5 10.4 0.0018 18.5 10.4 2.1 2 0 0 2 2 2 1 YL1 nuclear protein RNA_helicase PF00910.22 KXZ52854.1 - 0.0048 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase PTCB-BRCT PF12738.7 KXZ52854.1 - 0.025 14.5 0.0 0.073 13.0 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain Zeta_toxin PF06414.12 KXZ52854.1 - 0.038 13.3 0.2 0.076 12.3 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin SAGA-Tad1 PF12767.7 KXZ52854.1 - 0.066 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NOA36 PF06524.12 KXZ52854.1 - 3.6 6.8 17.1 0.7 9.2 0.3 2.4 2 0 0 2 2 2 0 NOA36 protein Abhydrolase_6 PF12697.7 KXZ52855.1 - 5.2e-25 89.3 9.2 5.2e-25 89.3 9.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ52855.1 - 9.4e-13 48.4 0.0 3.5e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ52855.1 - 1.7e-07 30.7 2.9 0.00022 20.6 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXZ52855.1 - 0.16 11.7 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Trans_coact PF16805.5 KXZ52856.1 - 0.051 13.7 1.0 0.087 12.9 1.0 1.3 1 0 0 1 1 1 0 Phage late-transcription coactivator Sec1 PF00995.23 KXZ52857.1 - 3.7e-104 350.0 0.0 4.2e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-rbx1 PF12678.7 KXZ52858.1 - 1.6e-12 47.5 6.2 2.8e-12 46.7 6.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXZ52858.1 - 5.3e-11 42.7 7.5 5.3e-11 42.7 7.5 1.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ52858.1 - 5.8e-09 35.6 8.1 1.2e-08 34.6 8.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ52858.1 - 2e-08 34.0 8.2 3.1e-08 33.3 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ52858.1 - 4e-08 33.1 3.1 4e-08 33.1 3.1 1.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXZ52858.1 - 1.1e-07 31.8 2.8 2e-07 31.0 2.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXZ52858.1 - 2.5e-06 27.2 2.2 2.5e-06 27.2 2.2 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ52858.1 - 3.1e-06 27.0 6.2 3.1e-06 27.0 6.2 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXZ52858.1 - 9.8e-06 25.2 5.1 1.8e-05 24.3 5.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KXZ52858.1 - 0.001 19.1 6.2 0.0045 17.1 6.2 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXZ52858.1 - 0.0074 16.1 4.2 0.73 9.7 1.5 2.2 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 KXZ52858.1 - 0.04 13.8 0.5 0.32 10.9 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 KXZ52858.1 - 0.055 13.3 6.0 0.25 11.2 6.3 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KXZ52858.1 - 0.065 13.1 4.4 0.098 12.5 4.4 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 KXZ52858.1 - 0.075 13.1 4.2 0.28 11.2 4.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 KXZ52858.1 - 0.075 12.7 5.3 0.14 11.8 5.3 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Fer2_4 PF13510.6 KXZ52858.1 - 0.13 12.3 0.2 0.26 11.3 0.1 1.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FANCL_C PF11793.8 KXZ52858.1 - 0.28 11.4 7.3 4.4 7.5 7.3 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain CLP_protease PF00574.23 KXZ52859.1 - 4.1e-73 245.2 0.1 6.7e-73 244.5 0.1 1.3 1 0 0 1 1 1 1 Clp protease HA2 PF04408.23 KXZ52861.1 - 9.5e-20 70.9 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXZ52861.1 - 3.9e-12 46.4 0.0 4.1e-11 43.1 0.0 2.5 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXZ52861.1 - 3.6e-11 43.4 0.0 6.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ52861.1 - 6e-05 22.9 0.2 0.19 11.5 0.0 2.3 1 1 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 KXZ52861.1 - 0.0028 17.9 1.7 0.2 11.9 1.7 2.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXZ52861.1 - 0.0046 16.1 0.0 0.0087 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 KXZ52861.1 - 0.017 14.6 0.1 0.045 13.2 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KXZ52861.1 - 0.017 15.5 0.2 0.069 13.5 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KXZ52861.1 - 0.026 14.2 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXZ52861.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ52861.1 - 0.048 13.2 0.3 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXZ52861.1 - 0.087 12.7 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KXZ52861.1 - 0.15 12.4 0.8 1.7 8.9 0.8 2.3 1 1 0 1 1 1 0 AAA domain Glyco_hydro_9 PF00759.19 KXZ52862.1 - 7.2e-45 154.1 5.5 7.2e-45 154.1 5.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 Laminin_G_3 PF13385.6 KXZ52862.1 - 2.1e-16 60.4 17.2 9e-06 25.9 0.6 4.6 5 0 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily CelD_N PF02927.14 KXZ52862.1 - 3.1e-13 50.4 0.0 7.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Cellulase N-terminal ig-like domain Laminin_G_2 PF02210.24 KXZ52862.1 - 3.3e-09 37.4 0.0 0.014 16.0 0.0 3.5 3 0 0 3 3 3 2 Laminin G domain PKD PF00801.20 KXZ52862.1 - 2.1e-05 24.3 0.4 9.4e-05 22.2 0.4 2.2 1 0 0 1 1 1 1 PKD domain Laminin_G_1 PF00054.23 KXZ52862.1 - 3.8e-05 23.9 0.0 0.057 13.6 0.0 3.4 3 0 0 3 3 3 2 Laminin G domain Polysacc_lyase PF14099.6 KXZ52862.1 - 7.9e-05 22.6 0.0 0.011 15.6 0.0 3.1 3 0 0 3 3 3 1 Polysaccharide lyase CAP_N PF01213.19 KXZ52862.1 - 1.6 8.1 4.2 3.2 7.1 4.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA PF00004.29 KXZ52863.1 - 1.3e-28 100.0 0.0 2.5e-28 99.2 0.0 1.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ52863.1 - 1.3e-10 40.9 0.5 3.2e-10 39.7 0.5 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KXZ52863.1 - 3.6e-06 26.9 0.0 6.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_11 PF13086.6 KXZ52864.1 - 5e-13 49.4 0.0 1.1e-09 38.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KXZ52864.1 - 1.1e-12 48.1 0.0 1.6e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ52864.1 - 1.8e-11 44.1 1.3 1.7e-10 40.9 1.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ52864.1 - 4.7e-07 30.2 0.0 1.4e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXZ52864.1 - 3.5e-05 23.6 0.6 0.00018 21.3 0.6 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXZ52864.1 - 0.0071 16.1 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PDDEXK_1 PF12705.7 KXZ52864.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily AAA_22 PF13401.6 KXZ52864.1 - 0.19 12.0 0.0 0.77 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KXZ52864.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 KXZ52864.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KXZ52864.1 - 3 8.2 6.8 3 8.2 0.1 4.2 6 0 0 6 6 6 0 AAA ATPase domain Ank_2 PF12796.7 KXZ52865.1 - 3.4e-09 37.2 0.0 0.02 15.5 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ52865.1 - 6.8e-08 32.9 1.7 13 6.5 0.1 6.9 6 2 1 7 7 7 3 Ankyrin repeats (many copies) DUF3883 PF13020.6 KXZ52866.1 - 2.1e-17 62.9 0.0 3.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Spc24 PF08286.11 KXZ52867.1 - 2.6e-07 30.8 0.2 2.9e-07 30.7 0.2 1.0 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 P4Ha_N PF08336.11 KXZ52867.1 - 0.013 15.5 0.2 0.014 15.4 0.2 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4615 PF15393.6 KXZ52867.1 - 0.024 15.2 0.2 0.026 15.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) TALPID3 PF15324.6 KXZ52867.1 - 0.075 10.7 1.4 0.085 10.5 1.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target RNA_binding PF01877.17 KXZ52867.1 - 0.087 13.1 0.0 0.12 12.7 0.0 1.3 1 1 0 1 1 1 0 RNA binding RAP PF08373.10 KXZ52868.1 - 2.8e-09 36.9 0.0 5.7e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 RAP domain Guanylate_kin PF00625.21 KXZ52869.1 - 1.5e-88 295.2 0.0 2.1e-40 138.3 0.0 7.0 7 0 0 7 7 7 6 Guanylate kinase ADK PF00406.22 KXZ52869.1 - 8.6e-27 94.1 0.0 1.9e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXZ52869.1 - 2.6e-15 57.0 0.0 2.1e-14 54.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXZ52869.1 - 6.6e-13 49.4 3.5 0.017 15.5 0.0 6.1 5 0 0 5 5 5 3 AAA ATPase domain Peptidase_C2 PF00648.21 KXZ52869.1 - 8.5e-09 34.8 0.0 1.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease AAA_22 PF13401.6 KXZ52869.1 - 9.6e-08 32.4 0.0 1.5 9.1 0.0 5.5 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 KXZ52869.1 - 1.5e-07 32.0 0.0 0.0015 19.1 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 KXZ52869.1 - 1.3e-06 28.6 0.0 2.5 8.3 0.0 5.1 4 0 0 4 4 4 2 AAA domain Cytidylate_kin PF02224.18 KXZ52869.1 - 4.9e-05 23.2 0.0 0.016 14.9 0.0 3.1 3 0 0 3 3 3 1 Cytidylate kinase RsgA_GTPase PF03193.16 KXZ52869.1 - 9.7e-05 22.3 0.0 0.26 11.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXZ52869.1 - 0.0013 18.8 0.0 1.3 9.2 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXZ52869.1 - 0.0055 17.2 0.0 13 6.3 0.0 3.4 3 0 0 3 3 3 0 ABC transporter Rad17 PF03215.15 KXZ52869.1 - 0.021 14.7 0.1 4.3 7.2 0.0 3.4 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_5 PF07728.14 KXZ52869.1 - 0.027 14.5 0.7 6.4 6.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 KXZ52869.1 - 0.051 13.9 1.1 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Phage_Cox PF10743.9 KXZ52869.1 - 0.058 13.5 0.0 24 5.1 0.0 3.6 3 0 0 3 3 3 0 Regulatory phage protein cox AAA_29 PF13555.6 KXZ52869.1 - 0.078 12.7 0.0 17 5.2 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KXZ52869.1 - 0.12 12.8 0.0 1.2e+02 3.2 0.0 3.7 3 0 0 3 3 3 0 RNA helicase ATP_bind_1 PF03029.17 KXZ52869.1 - 0.18 11.5 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KXZ52869.1 - 0.26 10.8 0.0 25 4.3 0.0 3.6 5 0 0 5 5 5 0 P-loop containing dynein motor region Mur_ligase_M PF08245.12 KXZ52871.1 - 2.7e-24 86.2 0.0 6.9e-13 49.0 0.0 2.4 2 1 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 KXZ52871.1 - 1.1e-15 57.6 0.0 4.5e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Glyco_tranf_2_3 PF13641.6 KXZ52872.1 - 5.8e-05 23.1 0.1 0.22 11.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXZ52872.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.6 KXZ52872.1 - 0.041 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family MMR_HSR1 PF01926.23 KXZ52873.1 - 4e-07 30.1 0.0 2.8e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase HMG_box_2 PF09011.10 KXZ52873.1 - 0.1 13.2 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain SRPRB PF09439.10 KXZ52873.1 - 0.15 11.5 0.0 0.33 10.3 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Na_Ca_ex PF01699.24 KXZ52875.1 - 3.6e-34 117.9 39.7 1.2e-18 67.5 16.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GLTP PF08718.11 KXZ52876.1 - 1.8e-22 80.3 0.0 6.4e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Mating_N PF12731.7 KXZ52876.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 Band_7 PF01145.25 KXZ52877.1 - 3.3e-22 79.3 1.5 5.6e-22 78.6 1.4 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KXZ52877.1 - 8.8e-05 21.7 4.6 0.00015 21.0 4.6 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 KXZ52877.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF4079 PF13301.6 KXZ52878.1 - 5e-48 162.9 0.1 5e-48 162.9 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) SNF2_N PF00176.23 KXZ52879.1 - 4.9e-103 344.5 0.0 1.6e-101 339.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain MMS19_N PF14500.6 KXZ52879.1 - 2.9e-49 168.0 0.0 6.1e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II PHD PF00628.29 KXZ52879.1 - 2.6e-07 30.4 1.6 2.6e-07 30.4 1.6 3.1 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 KXZ52879.1 - 0.00036 20.0 4.4 0.00036 20.0 4.4 1.9 2 0 0 2 2 2 1 PHD-finger Helicase_C PF00271.31 KXZ52879.1 - 0.00061 20.1 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MMS19_C PF12460.8 KXZ52879.1 - 0.004 16.3 0.0 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal zf-RING_UBOX PF13445.6 KXZ52879.1 - 0.21 11.7 5.4 0.58 10.2 5.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ52879.1 - 0.32 10.9 2.5 0.84 9.5 2.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXZ52879.1 - 1.3 8.8 5.2 2.9 7.7 5.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 KXZ52879.1 - 2.4 8.1 7.4 0.2 11.6 2.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SART-1 PF03343.13 KXZ52879.1 - 2.7 6.4 8.5 5.2 5.5 8.5 1.4 1 0 0 1 1 1 0 SART-1 family zf-RING_2 PF13639.6 KXZ52879.1 - 5.5 7.4 12.9 0.06 13.7 3.2 2.6 2 1 0 2 2 2 0 Ring finger domain S1 PF00575.23 KXZ52880.1 - 1.5e-18 66.9 0.5 2.8e-12 46.8 0.5 3.2 2 1 0 2 2 2 2 S1 RNA binding domain U-box PF04564.15 KXZ52881.1 - 7e-25 87.0 1.0 2.3e-24 85.3 0.2 2.3 3 0 0 3 3 3 1 U-box domain SPRY PF00622.28 KXZ52881.1 - 9e-20 71.0 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain ACCA PF03255.14 KXZ52882.1 - 5.5e-59 198.2 0.0 8.8e-59 197.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 KXZ52882.1 - 3.8e-14 52.2 0.1 4.9e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KXZ52882.1 - 0.002 17.6 0.1 0.0034 16.9 0.1 1.3 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) DUF1351 PF07083.11 KXZ52882.1 - 0.13 12.0 0.7 0.29 10.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) PRAI PF00697.22 KXZ52884.1 - 4.8e-29 101.5 0.0 2.6e-28 99.1 0.0 1.8 1 1 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase APC_N_CC PF16689.5 KXZ52885.1 - 0.021 14.9 0.0 0.07 13.2 0.0 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain LPP PF04728.13 KXZ52885.1 - 0.052 13.9 0.3 0.13 12.7 0.1 1.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF3584 PF12128.8 KXZ52885.1 - 0.062 10.8 0.0 0.076 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KXZ52885.1 - 0.064 13.3 0.1 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_4 PF13637.6 KXZ52887.1 - 5.4e-05 23.7 0.6 0.0028 18.2 0.0 3.2 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ52887.1 - 0.00024 21.6 0.0 0.012 16.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ52887.1 - 0.00031 21.0 0.3 0.98 10.2 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat PKS_DE PF18369.1 KXZ52888.1 - 0.056 14.0 9.9 10 6.7 4.1 5.0 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain cwf18 PF08315.12 KXZ52889.1 - 1.5e-28 100.1 6.4 1.9e-28 99.8 6.4 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor TauD PF02668.16 KXZ52889.1 - 0.018 14.9 0.5 0.021 14.6 0.5 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DnaJ PF00226.31 KXZ52890.1 - 3.2e-24 84.8 1.7 4.6e-24 84.3 1.7 1.2 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 KXZ52890.1 - 3.5e-24 84.8 0.1 9.1e-24 83.4 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Armet PF10208.9 KXZ52890.1 - 4e-06 26.8 0.0 6.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Thioredoxin_8 PF13905.6 KXZ52890.1 - 0.044 14.1 0.0 0.62 10.4 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like SAP PF02037.27 KXZ52890.1 - 0.058 13.2 0.3 0.12 12.1 0.3 1.6 1 0 0 1 1 1 0 SAP domain AhpC-TSA PF00578.21 KXZ52890.1 - 0.061 13.2 0.0 0.76 9.7 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_2 PF13098.6 KXZ52890.1 - 0.2 12.2 0.0 5.3 7.6 0.0 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain zf-C2HE PF16278.5 KXZ52890.1 - 0.2 12.1 0.0 0.46 11.0 0.0 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger OST-HTH PF12872.7 KXZ52891.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain B-block_TFIIIC PF04182.12 KXZ52892.1 - 4.8e-11 42.7 0.0 1.8e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC AF-4 PF05110.13 KXZ52893.1 - 7 4.6 15.6 12 3.8 15.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein rRNA_methylase PF06962.12 KXZ52894.1 - 1.7e-33 115.5 0.0 2e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_31 PF13847.6 KXZ52894.1 - 6.2e-09 35.8 0.0 1.2e-08 34.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ52894.1 - 4e-08 33.9 0.1 7.7e-08 32.9 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ52894.1 - 5.9e-05 22.5 0.0 0.00018 20.9 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXZ52894.1 - 0.005 17.6 0.0 0.011 16.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.10 KXZ52894.1 - 0.025 14.3 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 KXZ52894.1 - 0.046 13.3 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KXZ52894.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KXZ52894.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KXZ52894.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 KXZ52895.1 - 2.4e-37 128.8 0.0 2.9e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52895.1 - 5.2e-30 104.6 0.0 1.1e-29 103.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ52895.1 - 0.00016 21.1 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ52895.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dam PF05869.11 KXZ52896.1 - 2e-07 30.7 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) DUF2052 PF09747.9 KXZ52896.1 - 1.6 8.8 4.5 2.4 8.2 4.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SUIM_assoc PF16619.5 KXZ52897.1 - 0.66 10.1 11.5 3.1 7.9 3.3 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Guanylate_cyc PF00211.20 KXZ52898.1 - 1.6e-43 148.5 0.0 3e-37 128.0 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain GAF_2 PF13185.6 KXZ52898.1 - 0.015 15.6 0.1 0.087 13.1 0.0 2.4 2 0 0 2 2 2 0 GAF domain GAF PF01590.26 KXZ52898.1 - 0.018 15.7 0.0 0.083 13.5 0.0 2.3 1 0 0 1 1 1 0 GAF domain 3Beta_HSD PF01073.19 KXZ52899.1 - 5.3e-70 235.6 0.0 6.8e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXZ52899.1 - 2.4e-35 122.2 0.0 3.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ52899.1 - 1.6e-15 57.3 0.0 1.7e-14 54.0 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXZ52899.1 - 1.3e-14 54.5 0.0 2.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXZ52899.1 - 2.7e-13 49.7 0.0 8.2e-13 48.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXZ52899.1 - 6e-12 45.3 0.0 1.9e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KXZ52899.1 - 8.3e-09 35.0 0.0 1.7e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KXZ52899.1 - 1.7e-05 24.5 0.0 5.5e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 KXZ52899.1 - 0.0058 16.6 0.1 0.028 14.3 0.0 2.0 1 1 0 2 2 2 1 KR domain Mpp10 PF04006.12 KXZ52900.1 - 6.3e-119 398.2 16.4 9e-119 397.7 16.4 1.1 1 0 0 1 1 1 1 Mpp10 protein Amino_oxidase PF01593.24 KXZ52902.1 - 1.6e-11 44.2 0.0 5.1e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ52902.1 - 3.6e-09 36.7 0.1 8.5e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXZ52902.1 - 0.00015 21.1 0.2 0.077 12.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ52902.1 - 0.001 18.4 0.1 0.0016 17.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXZ52902.1 - 0.0035 16.6 0.4 0.0053 16.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 KXZ52902.1 - 0.0063 16.8 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 KXZ52902.1 - 0.012 15.2 0.1 0.048 13.2 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXZ52902.1 - 0.048 13.0 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ52902.1 - 0.057 12.5 0.2 0.084 11.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DUF1344 PF07076.11 KXZ52902.1 - 0.062 13.2 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) HI0933_like PF03486.14 KXZ52902.1 - 0.1 11.3 0.3 0.17 10.5 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KXZ52902.1 - 0.15 12.1 0.2 0.98 9.4 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KXZ52902.1 - 0.24 10.4 0.2 0.42 9.6 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A zf_CCCH_4 PF18345.1 KXZ52902.1 - 1.7 8.8 3.8 0.75 9.9 0.4 2.2 2 0 0 2 2 2 0 Zinc finger domain DUF4486 PF14858.6 KXZ52903.1 - 4.7e-30 104.6 0.3 2.7e-26 92.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4486) RRM_1 PF00076.22 KXZ52904.1 - 2.3e-16 59.4 0.2 1.2e-11 44.2 0.1 2.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ52904.1 - 7.6e-06 25.5 0.0 1.2e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXZ52904.1 - 0.0069 16.4 0.2 0.094 12.7 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KXZ52904.1 - 0.0089 16.0 0.0 0.034 14.1 0.0 1.9 2 0 0 2 2 2 1 DbpA RNA binding domain DUF1866 PF08952.11 KXZ52904.1 - 0.067 13.0 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Limkain-b1 PF11608.8 KXZ52904.1 - 0.071 13.2 0.4 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 Limkain b1 RRM_occluded PF16842.5 KXZ52904.1 - 0.18 11.7 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif VWA PF00092.28 KXZ52905.1 - 1.8e-24 86.9 0.0 2.3e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXZ52905.1 - 1.3e-17 64.4 0.5 2.3e-17 63.6 0.5 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXZ52905.1 - 2.8e-10 40.3 0.5 4e-10 39.8 0.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXZ52905.1 - 2.6e-06 27.0 1.9 3.5e-06 26.6 1.9 1.1 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.9 KXZ52905.1 - 0.011 15.9 0.2 0.022 14.9 0.2 1.5 1 1 0 1 1 1 0 VWA-like domain (DUF2201) mRNA_triPase PF02940.15 KXZ52905.1 - 0.17 11.6 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain SUIM_assoc PF16619.5 KXZ52906.1 - 0.021 14.9 5.5 0.029 14.4 5.5 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 YajC PF02699.15 KXZ52906.1 - 0.21 11.5 3.5 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit Spt20 PF12090.8 KXZ52906.1 - 1 8.9 5.8 1.1 8.8 5.8 1.2 1 0 0 1 1 1 0 Spt20 family Aldo_ket_red PF00248.21 KXZ52907.1 - 1.2e-50 172.3 0.0 1.6e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KXZ52908.1 - 2.3e-39 134.9 0.6 3.5e-39 134.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ52908.1 - 2.9e-32 112.1 0.8 4.2e-32 111.6 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ52908.1 - 4.8e-09 36.4 0.8 7.2e-09 35.8 0.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXZ52908.1 - 0.013 15.0 0.3 0.025 14.0 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family COX15-CtaA PF02628.15 KXZ52909.1 - 0.0058 15.8 1.9 0.0058 15.8 1.9 1.4 2 0 0 2 2 2 1 Cytochrome oxidase assembly protein LCIB_C_CA PF18599.1 KXZ52909.1 - 1.8 7.8 7.2 2.8 7.2 7.2 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SecA_PP_bind PF01043.20 KXZ52910.1 - 1.1e-05 26.0 0.1 1.2e-05 25.9 0.1 1.1 1 0 0 1 1 1 1 SecA preprotein cross-linking domain Mpp10 PF04006.12 KXZ52911.1 - 1.7e-88 297.7 1.9 3.7e-63 214.0 0.1 2.1 1 1 1 2 2 2 2 Mpp10 protein RAP PF08373.10 KXZ52911.1 - 6.8e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RAP domain DUF840 PF05801.11 KXZ52911.1 - 0.15 12.1 0.0 16 5.6 0.0 3.5 3 1 1 4 4 4 0 Lagovirus protein of unknown function (DUF840) DUF748 PF05359.11 KXZ52911.1 - 0.15 12.2 0.1 10 6.3 0.0 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF748) SecA_DEAD PF07517.14 KXZ52913.1 - 9.5e-122 405.8 0.0 1.3e-121 405.4 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 KXZ52913.1 - 2.2e-28 99.7 0.0 2e-24 86.8 0.0 2.9 2 1 0 2 2 2 2 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 KXZ52913.1 - 2e-23 83.1 0.0 4.7e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 KXZ52913.1 - 0.0019 18.0 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sipho_Gp37 PF14594.6 KXZ52913.1 - 0.032 13.3 0.0 0.057 12.4 0.0 1.5 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein Ax_dynein_light PF10211.9 KXZ52914.1 - 0.0015 18.6 0.3 0.0022 18.0 0.3 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain Golgin_A5 PF09787.9 KXZ52916.1 - 1.4e-11 44.5 33.1 8.4e-11 41.9 22.5 2.9 1 1 1 2 2 2 2 Golgin subfamily A member 5 Spc7 PF08317.11 KXZ52916.1 - 0.0028 16.6 9.6 0.0028 16.6 9.6 3.0 1 1 2 3 3 3 1 Spc7 kinetochore protein Sec34 PF04136.15 KXZ52916.1 - 9.5 6.1 12.3 1.9 8.3 3.3 2.9 2 1 1 3 3 3 0 Sec34-like family Peptidase_C14 PF00656.22 KXZ52917.1 - 6.4e-46 157.3 0.0 7.6e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain FBPase PF00316.20 KXZ52918.1 - 2.5e-57 193.4 0.1 3.4e-57 193.0 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DUF4447 PF14590.6 KXZ52918.1 - 0.33 10.7 1.9 7.8 6.2 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4447) C8 PF08742.11 KXZ52918.1 - 0.98 9.9 3.4 1.1 9.7 1.7 1.9 2 0 0 2 2 2 0 C8 domain zf-MYND PF01753.18 KXZ52919.1 - 9e-10 38.5 7.4 1.6e-09 37.7 7.4 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ52920.1 - 1.7e-09 37.6 8.2 2.7e-09 36.9 8.2 1.4 1 0 0 1 1 1 1 MYND finger Zn_ribbon_17 PF17120.5 KXZ52920.1 - 0.12 12.1 4.3 0.22 11.1 4.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Glucosamine_iso PF01182.20 KXZ52922.1 - 2.1e-38 132.5 0.3 4e-37 128.3 0.3 2.2 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RAP PF08373.10 KXZ52923.1 - 3.9e-06 26.9 0.0 8.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 KXZ52923.1 - 0.00012 21.9 2.4 33 4.5 0.0 7.1 5 1 4 9 9 9 3 FAST kinase-like protein, subdomain 1 IF3_N PF05198.16 KXZ52924.1 - 0.016 15.5 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Ras PF00071.22 KXZ52925.1 - 1.7e-51 174.1 0.0 1.9e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ52925.1 - 1.5e-28 99.4 0.0 5.4e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ52925.1 - 3e-09 36.6 0.0 3.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXZ52925.1 - 0.041 13.4 0.0 0.078 12.5 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXZ52925.1 - 0.084 13.0 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-LSD1 PF06943.12 KXZ52926.1 - 1.4e-11 44.0 6.4 1.4e-11 44.0 6.4 1.8 2 0 0 2 2 2 1 LSD1 zinc finger RNA_POL_M_15KD PF02150.16 KXZ52926.1 - 0.0015 18.3 0.5 0.003 17.4 0.4 1.6 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 KXZ52926.1 - 0.015 15.2 0.2 0.02 14.8 0.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sad1_UNC PF07738.13 KXZ52927.1 - 1.6e-14 54.1 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Sugarporin_N PF11471.8 KXZ52927.1 - 2.8 8.0 14.6 1.2 9.2 5.4 4.2 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension Pkinase_Tyr PF07714.17 KXZ52928.1 - 2.7e-45 154.7 0.0 1.5e-43 149.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ52928.1 - 1.1e-38 133.2 0.0 2.8e-37 128.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KXZ52928.1 - 0.00028 20.9 0.1 0.0015 18.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ52928.1 - 0.045 12.5 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2165 PF09933.9 KXZ52928.1 - 2.8 8.0 4.7 3.5 7.7 0.5 2.2 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) TPR_11 PF13414.6 KXZ52930.1 - 1.1e-05 25.0 12.3 0.00051 19.7 0.1 4.4 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 KXZ52930.1 - 1.4e-05 25.3 21.9 0.016 15.4 7.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ52930.1 - 0.00015 21.6 24.2 0.02 15.0 0.3 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ52930.1 - 0.0035 17.3 8.0 1.2 9.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ52930.1 - 0.016 16.0 39.4 1.1 10.3 1.5 6.3 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ52930.1 - 0.027 15.1 6.3 21 6.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ52930.1 - 0.1 12.5 10.9 1.4 8.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ52930.1 - 0.34 10.8 16.4 0.26 11.2 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Tyrosinase PF00264.20 KXZ52931.1 - 1.6e-17 64.6 0.3 2.9e-17 63.7 0.3 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Retrotran_gag_2 PF14223.6 KXZ52933.1 - 1e-19 70.6 0.6 1.2e-18 67.2 0.6 2.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KXZ52933.1 - 4.2e-06 26.6 4.7 4.2e-06 26.6 4.7 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 KXZ52933.1 - 0.034 14.1 1.9 0.034 14.1 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 KXZ52933.1 - 0.061 13.6 0.0 9.4 6.6 0.0 2.7 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 KXZ52933.1 - 0.44 10.3 8.3 0.84 9.4 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KXZ52933.1 - 1.1 9.1 12.1 0.046 13.5 4.2 2.2 2 0 0 2 2 2 0 Zinc knuckle IGPS PF00218.21 KXZ52934.1 - 1.6e-78 263.4 0.0 1.9e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ThiG PF05690.14 KXZ52934.1 - 0.0076 15.6 0.8 0.9 8.8 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NDUFA12 PF05071.16 KXZ52935.1 - 4.3e-11 43.5 0.9 5.9e-11 43.1 0.9 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Alba PF01918.21 KXZ52936.1 - 4.2e-05 23.3 0.1 5e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Alba TPR_2 PF07719.17 KXZ52937.1 - 0.15 12.2 4.6 0.19 11.9 0.6 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 KXZ52938.1 - 5.4e-11 42.9 0.0 0.00028 21.4 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ52938.1 - 3.6e-08 33.8 3.6 0.02 15.4 0.1 5.0 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ52938.1 - 0.0083 16.6 3.0 78 4.3 0.0 6.6 6 2 2 8 8 8 0 Ankyrin repeat Phage_portal_2 PF05136.13 KXZ52938.1 - 1.3 8.1 4.1 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 Phage portal protein, lambda family DUF4476 PF14771.6 KXZ52939.1 - 5.6e-06 26.6 0.0 1.9e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4476) Vps5 PF09325.10 KXZ52939.1 - 0.025 14.1 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 Vps5 C terminal like Sirohm_synth_M PF14824.6 KXZ52939.1 - 0.079 12.4 0.2 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central TRAM_LAG1_CLN8 PF03798.16 KXZ52940.1 - 7.6e-17 61.7 5.0 2.6e-15 56.7 0.1 2.6 2 1 1 3 3 3 2 TLC domain Pkinase_Tyr PF07714.17 KXZ52942.1 - 1.5e-22 80.1 0.0 1.3e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ52942.1 - 6.9e-20 71.5 0.0 8.5e-19 67.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain DAGAT PF03982.13 KXZ52943.1 - 3.6e-36 124.6 0.0 4.8e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF4434 PF14488.6 KXZ52943.1 - 0.031 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) TRP PF06011.12 KXZ52944.1 - 7.8e-06 24.9 0.1 1.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel PT PF04886.12 KXZ52944.1 - 0.0013 18.3 6.4 0.0013 18.3 6.4 2.4 2 1 0 2 2 2 1 PT repeat Laminin_EGF PF00053.24 KXZ52944.1 - 0.031 14.4 6.2 0.03 14.5 2.6 2.4 2 0 0 2 2 2 0 Laminin EGF domain Methyltr_RsmB-F PF01189.17 KXZ52945.1 - 6.2e-23 81.5 0.0 3.5e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KXZ52945.1 - 0.0052 16.9 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase IBN_N PF03810.19 KXZ52946.1 - 0.0004 20.2 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Pkinase PF00069.25 KXZ52948.1 - 1.6e-31 109.6 0.0 1.1e-30 106.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52948.1 - 1.1e-29 103.5 0.0 5.5e-20 71.7 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ52948.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ52948.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ52948.1 - 0.029 14.3 0.2 0.083 12.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXZ52948.1 - 0.29 10.7 0.0 0.44 10.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KXZ52951.1 - 1.9e-27 96.3 0.0 3.2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52951.1 - 7.6e-26 90.9 0.0 1.2e-24 87.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ52951.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CcmD PF04995.14 KXZ52951.1 - 0.24 11.5 4.0 0.76 9.9 4.0 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Glycos_transf_2 PF00535.26 KXZ52952.1 - 1.2e-23 83.8 0.0 2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXZ52952.1 - 4e-11 43.2 0.0 6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KXZ52952.1 - 0.00074 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KXZ52952.1 - 0.022 15.3 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 SAP18 PF06487.12 KXZ52953.1 - 2.4e-17 63.4 0.0 3.5e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Methyltransf_24 PF13578.6 KXZ52954.1 - 0.00013 23.0 0.1 0.00022 22.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain zf-MYND PF01753.18 KXZ52955.1 - 1.4e-08 34.7 10.5 2.5e-08 33.8 10.5 1.4 1 0 0 1 1 1 1 MYND finger Glyco_transf_90 PF05686.12 KXZ52956.1 - 7.8e-33 114.0 0.3 1.3e-32 113.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 RAP PF08373.10 KXZ52956.1 - 1.6e-08 34.5 0.0 3.4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RAP domain Glyco_trans_1_2 PF13524.6 KXZ52956.1 - 0.0082 16.5 0.6 0.093 13.1 0.1 3.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 GCV_H PF01597.19 KXZ52957.1 - 6.4e-47 158.4 0.3 8.3e-47 158.1 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KXZ52957.1 - 0.00042 20.2 0.2 0.00074 19.4 0.2 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KXZ52957.1 - 0.00063 19.5 1.4 0.0014 18.4 0.2 2.0 1 1 1 2 2 2 1 Biotin-requiring enzyme HAS-barrel PF09378.10 KXZ52957.1 - 0.031 14.4 0.7 0.061 13.5 0.7 1.6 1 1 0 1 1 1 0 HAS barrel domain ADSL_C PF10397.9 KXZ52960.1 - 6.9 7.3 7.5 2.3 8.9 0.0 4.3 4 1 1 5 5 5 0 Adenylosuccinate lyase C-terminus CRAL_TRIO PF00650.20 KXZ52965.1 - 4.1e-19 68.8 0.0 5.4e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXZ52965.1 - 0.0086 16.2 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TPR_19 PF14559.6 KXZ52966.1 - 1.2e-12 48.2 9.2 0.0012 19.3 0.2 6.5 5 2 2 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ52966.1 - 5.6e-12 45.7 27.0 5e-07 29.8 2.8 4.8 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXZ52966.1 - 1.5e-05 25.4 3.2 5.4 8.1 0.1 6.3 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ52966.1 - 2.2e-05 24.7 17.1 0.15 12.4 1.9 6.7 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ52966.1 - 0.0006 19.6 10.4 1.4 9.2 0.2 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ52966.1 - 0.001 19.0 27.7 0.24 11.6 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ52966.1 - 0.0014 19.3 1.1 0.7 10.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ52966.1 - 0.018 14.9 7.3 13 5.8 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ52966.1 - 0.045 13.1 2.4 0.66 9.3 0.1 3.4 3 1 1 4 4 4 0 MalT-like TPR region TPR_1 PF00515.28 KXZ52966.1 - 0.076 12.9 21.1 1.1 9.2 0.2 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ52966.1 - 0.1 12.8 0.6 0.72 10.0 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ52966.1 - 0.11 13.2 13.6 0.4 11.4 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat RPN7 PF10602.9 KXZ52966.1 - 0.75 9.5 4.5 0.42 10.3 0.1 2.8 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_8 PF13181.6 KXZ52966.1 - 1 9.8 9.5 35 4.9 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Mob_synth_C PF06463.13 KXZ52967.1 - 1e-35 122.4 0.0 1.7e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KXZ52967.1 - 1.4e-31 110.1 0.0 2.1e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXZ52967.1 - 1.8e-06 28.3 0.0 3.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXZ52967.1 - 0.033 14.3 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain NTP_transf_2 PF01909.23 KXZ52970.1 - 2.1e-06 27.9 0.0 3.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KXZ52970.1 - 1.6e-05 25.0 0.0 5.7e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 KXZ52970.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF3510 PF12022.8 KXZ52971.1 - 3.6e-32 111.4 0.0 8.3e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KXZ52971.1 - 5e-24 84.9 1.3 1.4e-23 83.5 1.3 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 KXZ52971.1 - 0.00043 20.3 0.4 0.0018 18.3 0.4 2.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3995 PF13160.6 KXZ52972.1 - 0.01 16.2 1.6 0.016 15.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Pkinase PF00069.25 KXZ52973.1 - 1.6e-52 178.5 0.0 2.2e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52973.1 - 4.3e-26 91.7 0.0 7.2e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ52973.1 - 3.8e-05 23.1 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ52973.1 - 0.0019 17.1 0.1 0.0092 14.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXZ52973.1 - 0.048 13.6 0.1 0.048 13.6 0.1 3.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family ERM PF00769.19 KXZ52973.1 - 0.54 10.0 16.1 0.73 9.6 16.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HAD_2 PF13419.6 KXZ52974.1 - 3.3e-12 46.8 0.0 1.9e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ52974.1 - 1.7e-07 31.7 0.0 2.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ52974.1 - 2.7e-05 24.7 0.1 3.5e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ52974.1 - 0.00047 20.2 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KXZ52974.1 - 0.02 15.0 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DHC_N1 PF08385.12 KXZ52975.1 - 1.5e-183 611.5 4.9 1.5e-183 611.5 4.9 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KXZ52975.1 - 1.3e-139 464.8 0.3 1.3e-138 461.4 0.0 3.0 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ52975.1 - 8.9e-122 407.0 8.8 8.9e-122 407.0 8.8 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KXZ52975.1 - 2.9e-101 338.2 0.1 1.4e-100 336.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KXZ52975.1 - 1.1e-90 304.0 0.8 2.6e-90 302.8 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 KXZ52975.1 - 1.2e-89 300.8 8.7 3e-89 299.4 8.7 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KXZ52975.1 - 1.2e-80 269.8 1.9 3.9e-80 268.1 1.9 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ52975.1 - 2.8e-69 232.2 1.8 1.1e-64 217.3 0.5 4.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ52975.1 - 8.9e-46 155.7 0.1 1.8e-44 151.4 0.0 2.9 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXZ52975.1 - 3e-35 120.9 0.0 4.6e-34 117.1 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 KXZ52975.1 - 1.1e-30 105.8 0.8 4.3e-30 103.9 0.1 2.5 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KXZ52975.1 - 9.5e-26 90.4 2.4 4e-25 88.4 0.1 3.4 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KXZ52975.1 - 3.1e-19 69.4 0.4 1.1e-09 38.4 0.0 5.7 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 KXZ52975.1 - 2.4e-09 37.7 0.0 0.05 14.0 0.0 5.7 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXZ52975.1 - 6.4e-07 30.0 0.1 0.2 12.2 0.0 4.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KXZ52975.1 - 2.4e-05 24.6 0.0 8.8 6.6 0.0 5.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KXZ52975.1 - 3.9e-05 23.4 0.3 2.1 8.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXZ52975.1 - 0.00013 22.4 5.4 0.93 9.9 0.0 5.8 6 0 0 6 6 4 1 AAA ATPase domain Sigma54_activat PF00158.26 KXZ52975.1 - 0.0011 18.7 0.0 1.5 8.5 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain Tropomyosin PF00261.20 KXZ52975.1 - 0.0012 18.3 2.8 0.0012 18.3 2.8 4.6 6 0 0 6 6 6 2 Tropomyosin TsaE PF02367.17 KXZ52975.1 - 0.0016 18.5 1.8 20 5.2 0.1 4.3 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXZ52975.1 - 0.0035 17.7 0.6 15 6.1 0.0 4.4 4 0 0 4 4 3 0 RNA helicase NRDE-2 PF08424.10 KXZ52975.1 - 0.0066 15.6 1.5 0.018 14.2 1.5 1.7 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference PhoH PF02562.16 KXZ52975.1 - 0.0093 15.4 0.5 5.4 6.4 0.0 3.5 3 0 0 3 3 3 1 PhoH-like protein AAA_33 PF13671.6 KXZ52975.1 - 0.013 15.7 1.1 20 5.3 0.0 4.3 4 0 0 4 4 4 0 AAA domain EnY2 PF10163.9 KXZ52975.1 - 0.028 14.8 0.5 1.9 8.9 0.0 3.6 3 0 0 3 3 2 0 Transcription factor e(y)2 AAA_19 PF13245.6 KXZ52975.1 - 0.045 14.1 5.4 5.4 7.3 0.0 4.6 5 0 0 5 5 5 0 AAA domain AAA_28 PF13521.6 KXZ52975.1 - 0.1 12.8 0.2 18 5.5 0.1 3.8 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KXZ52975.1 - 3.2 7.3 4.4 6.8 6.2 0.0 3.8 5 0 0 5 5 5 0 AAA domain BST2 PF16716.5 KXZ52975.1 - 9.7 6.9 10.7 9.6 6.9 0.9 4.5 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Pkinase PF00069.25 KXZ52976.1 - 2e-52 178.2 0.0 2.3e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52976.1 - 3.8e-28 98.5 0.0 5e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ52976.1 - 6.9e-07 28.9 0.0 7.8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ52976.1 - 0.00052 20.0 5.7 0.021 14.8 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ52976.1 - 0.00088 18.2 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ52976.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXZ52976.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 2 0 0 2 2 2 0 Seadornavirus VP7 BPS1 PF05633.11 KXZ52977.1 - 0.12 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related SbcCD_C PF13558.6 KXZ52978.1 - 2.5e-09 37.2 0.2 4.7e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KXZ52978.1 - 8.2e-07 28.7 0.0 9.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 KXZ52978.1 - 0.062 13.8 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Methyltransf_34 PF11312.8 KXZ52978.1 - 0.081 12.2 0.5 0.29 10.4 0.0 1.8 1 1 1 2 2 2 0 Putative SAM-dependent methyltransferase DSPc PF00782.20 KXZ52979.1 - 1.5e-17 63.6 0.0 2.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXZ52979.1 - 0.015 15.6 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KXZ52979.1 - 0.025 14.2 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Arm PF00514.23 KXZ52980.1 - 0.0022 18.0 0.2 0.0022 18.0 0.2 7.9 11 0 0 11 11 11 2 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.6 KXZ52980.1 - 0.011 15.9 0.0 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 KXZ52980.1 - 0.016 15.6 3.8 0.016 15.6 3.8 5.4 4 1 1 5 5 5 0 HEAT repeats HEAT PF02985.22 KXZ52980.1 - 0.02 15.1 0.1 0.02 15.1 0.1 5.6 7 0 0 7 7 7 0 HEAT repeat Tfb2 PF03849.14 KXZ52981.1 - 1.2e-75 254.8 0.0 2.4e-75 253.8 0.0 1.5 1 1 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KXZ52981.1 - 1.9e-18 66.6 0.1 3.3e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KXZ52981.1 - 0.034 14.3 0.1 0.091 12.9 0.1 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Pentapeptide PF00805.22 KXZ52982.1 - 2.7e-14 52.4 12.5 2e-07 30.5 0.1 4.0 3 1 1 4 4 4 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 KXZ52982.1 - 2.7e-09 37.1 0.7 0.00022 21.3 0.3 3.1 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 KXZ52982.1 - 2.2e-07 30.9 0.0 2.5e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Ank_2 PF12796.7 KXZ52983.1 - 2.3e-24 85.8 0.3 3.6e-10 40.3 0.0 4.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ52983.1 - 3.6e-22 78.4 0.2 3.9e-09 36.9 0.0 4.9 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ52983.1 - 3.3e-21 73.1 5.1 4.2e-06 26.7 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KXZ52983.1 - 9.9e-20 70.1 8.9 7.6e-06 26.1 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KXZ52983.1 - 1.1e-18 67.0 4.5 6.9e-09 35.8 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 KXZ52983.1 - 2e-07 30.8 3.4 7.3e-07 28.9 3.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ52983.1 - 0.016 15.0 4.0 0.041 13.8 4.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ52983.1 - 0.16 12.3 7.4 1.3 9.5 7.4 2.4 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KXZ52983.1 - 1 9.4 9.7 0.42 10.6 6.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain PHD PF00628.29 KXZ52984.1 - 5.8e-09 35.7 0.4 7.9e-09 35.3 0.4 1.2 1 0 0 1 1 1 1 PHD-finger Tox-ART-HYE1 PF15634.6 KXZ52984.1 - 0.054 12.8 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase PHD_2 PF13831.6 KXZ52984.1 - 0.066 12.8 0.4 0.1 12.1 0.4 1.3 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_10 PF10058.9 KXZ52984.1 - 0.17 11.7 0.4 0.27 11.0 0.4 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein SET PF00856.28 KXZ52986.1 - 2.5e-06 28.0 0.0 4.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXZ52986.1 - 0.0033 18.1 0.0 0.0054 17.4 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KXZ52987.1 - 0.0014 19.0 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXZ52987.1 - 0.024 15.3 0.1 0.042 14.5 0.1 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding SET PF00856.28 KXZ52988.1 - 4.1e-10 40.3 0.0 6.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXZ52988.1 - 1.8e-06 28.6 1.7 0.014 16.1 0.2 2.3 1 1 1 2 2 2 2 Rubisco LSMT substrate-binding Complex1_LYR_1 PF13232.6 KXZ52988.1 - 0.0079 16.8 1.4 6.2 7.5 0.2 2.6 2 1 0 2 2 2 2 Complex1_LYR-like PDEase_I PF00233.19 KXZ52989.1 - 3.8e-72 242.8 0.1 4.7e-72 242.6 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Voltage_CLC PF00654.20 KXZ52990.1 - 4e-75 253.3 24.7 6.7e-75 252.5 24.7 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KXZ52990.1 - 1.1e-05 25.8 0.0 0.028 14.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain SRCR PF00530.18 KXZ52991.1 - 6e-144 469.5 27.2 4.6e-18 65.6 0.1 15.4 13 3 1 14 14 14 14 Scavenger receptor cysteine-rich domain VOMI PF03762.17 KXZ52991.1 - 2.1e-11 44.2 0.1 5.2e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) SRCR_2 PF15494.6 KXZ52991.1 - 1.8e-07 31.6 20.6 0.19 12.3 0.4 9.0 10 0 0 10 10 10 3 Scavenger receptor cysteine-rich domain Pkinase PF00069.25 KXZ52993.1 - 7.7e-33 114.0 0.0 5.5e-32 111.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52993.1 - 1e-30 106.9 0.0 8.8e-28 97.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ52993.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ52993.1 - 0.0078 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ52993.1 - 0.042 12.8 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXZ52993.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ52994.1 - 9.9e-34 116.9 0.0 7.4e-33 114.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ52994.1 - 3.6e-32 111.7 0.0 3.1e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ52994.1 - 0.00024 20.5 0.0 0.00037 19.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ52994.1 - 0.0063 16.5 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ52994.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXZ52994.1 - 0.051 12.5 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Vps51 PF08700.11 KXZ52995.1 - 2.2e-21 75.7 3.2 2.2e-21 75.7 3.2 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 KXZ52995.1 - 1.3e-11 43.8 4.9 1.8e-11 43.3 4.9 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 KXZ52995.1 - 3.2e-09 36.9 0.4 4.7e-09 36.3 0.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.11 KXZ52995.1 - 3.6e-07 30.3 0.2 8.1e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KXZ52995.1 - 1.9e-06 28.1 6.5 3.2e-06 27.3 6.5 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Vps54_N PF10475.9 KXZ52995.1 - 0.00013 21.4 4.6 0.00016 21.1 3.9 1.4 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KXZ52995.1 - 0.00052 18.7 4.0 0.00089 18.0 4.0 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec8_exocyst PF04048.14 KXZ52995.1 - 0.0018 18.2 4.4 0.0029 17.5 4.4 1.3 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain VPS28 PF03997.12 KXZ52995.1 - 0.0064 16.2 2.2 0.01 15.5 2.2 1.3 1 0 0 1 1 1 1 VPS28 protein Histone_HNS PF00816.21 KXZ52995.1 - 0.031 15.1 0.1 0.031 15.1 0.1 2.6 2 1 1 3 3 2 0 H-NS histone family Tantalus PF15386.6 KXZ52995.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Drosophila Tantalus-like Prominin PF05478.11 KXZ52995.1 - 0.04 11.9 1.3 0.057 11.4 1.3 1.2 1 0 0 1 1 1 0 Prominin NleF_casp_inhib PF16809.5 KXZ52995.1 - 0.049 13.5 0.7 0.073 13.0 0.7 1.2 1 0 0 1 1 1 0 NleF caspase inhibitor DUF1664 PF07889.12 KXZ52995.1 - 0.31 11.1 6.7 0.39 10.8 5.7 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KXZ52995.1 - 0.35 10.9 8.8 0.7 9.9 8.8 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 KXZ52995.1 - 1.2 9.6 7.5 1.3 9.6 5.2 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF2115 PF09888.9 KXZ52995.1 - 1.4 9.4 3.9 2.5 8.6 3.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) CLZ PF16526.5 KXZ52995.1 - 3.6 8.0 7.5 1.9 8.9 3.0 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribosomal_60s PF00428.19 KXZ52995.1 - 6.7 7.4 11.6 1.6 9.4 5.0 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Fib_alpha PF08702.10 KXZ52995.1 - 9 6.5 8.6 1.5 9.0 3.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SRCR PF00530.18 KXZ52996.1 - 9.6e-19 67.7 6.3 1e-13 51.6 1.2 2.2 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ52996.1 - 0.0081 16.7 0.2 0.012 16.1 0.2 1.5 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 KXZ52997.1 - 2.5e-166 541.4 32.2 5.3e-18 65.4 0.7 13.8 13 0 0 13 13 13 13 Scavenger receptor cysteine-rich domain VOMI PF03762.17 KXZ52997.1 - 1.8e-10 41.2 0.3 6.3e-10 39.5 0.3 1.9 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) SRCR_2 PF15494.6 KXZ52997.1 - 8.8e-10 39.0 33.7 0.047 14.2 0.1 11.9 13 0 0 13 13 13 5 Scavenger receptor cysteine-rich domain YecR PF13992.6 KXZ52997.1 - 0.047 14.0 19.2 15 6.0 0.0 9.2 10 0 0 10 10 10 0 YecR-like lipoprotein Vps51 PF08700.11 KXZ52998.1 - 8.3e-16 57.9 2.6 8.3e-16 57.9 2.6 1.8 1 1 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KXZ52998.1 - 6e-09 35.0 2.2 8e-09 34.6 2.2 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 KXZ52998.1 - 1.8e-05 24.6 1.2 5.6e-05 23.0 1.2 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps54_N PF10475.9 KXZ52998.1 - 0.0053 16.1 3.8 0.0054 16.0 2.9 1.4 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KXZ52998.1 - 0.0083 14.7 1.8 0.013 14.1 1.8 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 COG2 PF06148.11 KXZ52998.1 - 0.0097 16.0 2.4 0.026 14.6 2.4 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KXZ52998.1 - 0.044 14.0 3.0 0.082 13.1 3.0 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Histone_HNS PF00816.21 KXZ52998.1 - 0.056 14.3 0.1 0.056 14.3 0.1 2.3 2 1 0 2 2 2 0 H-NS histone family OmpH PF03938.14 KXZ52998.1 - 0.079 13.3 1.8 0.16 12.3 1.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NleF_casp_inhib PF16809.5 KXZ52998.1 - 0.11 12.4 0.5 0.18 11.7 0.5 1.2 1 0 0 1 1 1 0 NleF caspase inhibitor KxDL PF10241.9 KXZ52998.1 - 0.29 11.4 5.6 0.46 10.8 0.4 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Prominin PF05478.11 KXZ52998.1 - 0.52 8.2 2.1 0.74 7.7 2.1 1.1 1 0 0 1 1 1 0 Prominin Ribosomal_60s PF00428.19 KXZ52998.1 - 5 7.8 19.7 1.2 9.7 4.6 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SRCR PF00530.18 KXZ52999.1 - 2.7e-176 573.3 49.7 1.5e-18 67.1 0.9 15.0 13 2 1 14 14 14 14 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ52999.1 - 4e-13 49.7 35.3 0.068 13.7 0.0 11.0 12 0 0 12 12 12 6 Scavenger receptor cysteine-rich domain VOMI PF03762.17 KXZ52999.1 - 9.5e-09 35.6 0.2 9.5e-09 35.6 0.2 2.4 2 0 0 2 2 2 1 Vitelline membrane outer layer protein I (VOMI) Hepsin-SRCR PF09272.10 KXZ52999.1 - 0.0017 18.8 3.4 54 4.4 0.0 7.0 9 0 0 9 9 9 0 Hepsin, SRCR domain YecR PF13992.6 KXZ52999.1 - 0.59 10.5 14.7 8.9 6.7 0.0 7.0 9 0 0 9 9 9 0 YecR-like lipoprotein Chitin_synth_1N PF08407.11 KXZ53000.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase N-terminal SRCR PF00530.18 KXZ53001.1 - 2.6e-07 31.1 1.1 6.6e-07 29.8 1.1 1.8 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ53001.1 - 0.005 17.4 0.0 0.0073 16.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Mito_carr PF00153.27 KXZ53004.1 - 2.9e-46 155.3 15.2 7.3e-20 70.7 0.1 4.6 3 1 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.11 KXZ53004.1 - 0.18 11.6 0.3 1.4 8.8 0.0 2.7 1 1 1 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ATP-synt_D PF01813.17 KXZ53005.1 - 4.3e-68 229.0 1.8 5.9e-68 228.6 1.8 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Prefoldin PF02996.17 KXZ53005.1 - 0.37 10.7 4.9 0.4 10.6 0.5 2.5 2 1 0 2 2 2 0 Prefoldin subunit NifU PF01106.17 KXZ53006.1 - 6.6e-38 128.7 5.1 4.1e-25 87.7 0.2 2.2 2 0 0 2 2 2 2 NifU-like domain HetR_C PF18460.1 KXZ53007.1 - 0.057 13.3 3.0 0.1 12.5 0.0 2.9 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Ribosomal_L39 PF00832.20 KXZ53008.1 - 1.6e-22 78.8 10.0 3e-22 78.0 10.0 1.4 1 0 0 1 1 1 1 Ribosomal L39 protein MMtag PF10159.9 KXZ53010.1 - 6.6e-27 93.6 3.7 6.6e-27 93.6 3.7 2.3 2 0 0 2 2 2 1 Multiple myeloma tumor-associated Mito_fiss_reg PF05308.11 KXZ53010.1 - 0.23 11.5 3.4 0.086 12.9 0.8 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator NARP1 PF12569.8 KXZ53010.1 - 0.29 10.0 8.5 0.42 9.4 8.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 KXZ53010.1 - 9.9 6.2 10.1 20 5.2 10.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FIST PF08495.10 KXZ53013.1 - 0.041 13.9 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 FIST N domain Peptidase_M17_N PF02789.17 KXZ53014.1 - 1.1 9.2 5.2 2.4 8.1 5.2 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Acyltransferase PF01553.21 KXZ53015.1 - 2.5e-12 46.5 0.0 4.8e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.13 KXZ53015.1 - 0.22 10.7 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Vta1 PF04652.16 KXZ53016.1 - 0.09 12.7 0.1 0.18 11.7 0.1 1.5 1 1 1 2 2 2 0 Vta1 like BLM10_mid PF16507.5 KXZ53016.1 - 0.11 11.1 0.1 0.13 10.9 0.1 1.0 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region NAD_binding_3 PF03447.16 KXZ53017.1 - 1e-22 81.0 0.0 3.2e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 KXZ53017.1 - 1.1e-17 63.5 0.6 2.2e-10 40.1 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KXZ53017.1 - 2.3e-16 59.3 1.1 6.3e-07 29.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain Homoserine_dh PF00742.19 KXZ53017.1 - 8e-05 22.6 0.2 0.00044 20.2 0.0 2.2 2 1 0 2 2 2 1 Homoserine dehydrogenase ACT_6 PF13740.6 KXZ53017.1 - 0.0024 17.8 0.2 0.71 9.9 0.1 3.1 3 0 0 3 3 3 1 ACT domain LytR_C PF13399.6 KXZ53017.1 - 0.0099 16.8 0.2 1.6 9.8 0.0 2.8 1 1 1 2 2 2 1 LytR cell envelope-related transcriptional attenuator GGDEF_2 PF17853.1 KXZ53017.1 - 0.095 13.0 0.6 1.2 9.4 0.1 2.3 1 1 0 2 2 2 0 GGDEF-like domain Glyco_transf_10 PF00852.19 KXZ53018.1 - 5.6e-16 58.8 3.0 1.5e-14 54.1 0.1 2.4 1 1 1 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KXZ53018.1 - 0.00023 21.6 0.2 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal DUF4813 PF16072.5 KXZ53020.1 - 1.6 8.3 22.3 2.7 7.6 22.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF563 PF04577.14 KXZ53021.1 - 4.4e-11 43.3 0.0 6.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Protocadherin PF08374.11 KXZ53021.1 - 0.083 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Protocadherin WD40 PF00400.32 KXZ53022.1 - 2.3e-108 351.0 29.5 4e-10 40.1 0.3 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ53022.1 - 1.1e-46 157.0 0.1 0.00023 21.4 0.0 12.8 3 3 9 13 13 13 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXZ53022.1 - 1.5e-20 72.6 0.0 0.46 10.5 0.0 11.1 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXZ53022.1 - 1.3e-17 63.8 8.4 1.1 8.2 0.0 12.0 2 2 9 14 14 14 7 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KXZ53022.1 - 3.2e-10 39.5 0.3 6.6 6.5 0.0 8.6 8 0 0 8 8 8 1 Proteasome subunit A N-terminal signature AAA_16 PF13191.6 KXZ53022.1 - 6.8e-05 23.3 0.2 0.00026 21.4 0.2 2.0 1 0 0 1 1 1 1 AAA ATPase domain Cytochrom_D1 PF02239.16 KXZ53022.1 - 0.00017 20.3 0.3 1.4 7.4 0.0 5.1 4 3 3 7 7 7 1 Cytochrome D1 heme domain WD40_like PF17005.5 KXZ53022.1 - 0.00017 21.0 0.0 0.0034 16.8 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 KXZ53022.1 - 0.00059 19.3 2.7 27 4.0 0.0 7.3 5 2 2 8 8 8 0 Neuroblastoma-amplified sequence, N terminal Ret2_MD PF18528.1 KXZ53022.1 - 0.0021 18.4 0.0 23 5.4 0.0 5.3 6 0 0 6 6 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain IKI3 PF04762.12 KXZ53022.1 - 0.0025 15.9 0.1 0.0069 14.4 0.1 1.7 1 0 0 1 1 1 1 IKI3 family DUF2415 PF10313.9 KXZ53022.1 - 0.04 13.8 2.6 3.6 7.6 0.0 4.5 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) TFIIIC_delta PF12657.7 KXZ53022.1 - 0.091 12.7 1.7 28 4.6 0.1 4.4 5 0 0 5 5 5 0 Transcription factor IIIC subunit delta N-term NACHT PF05729.12 KXZ53022.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PALB2_WD40 PF16756.5 KXZ53022.1 - 0.23 10.3 6.1 5 6.0 0.4 4.4 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain DUF563 PF04577.14 KXZ53023.1 - 1.1e-26 94.3 0.0 1.7e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ephrin_rec_like PF07699.13 KXZ53023.1 - 0.00035 20.3 14.4 0.012 15.4 4.8 2.8 1 1 2 3 3 3 3 Putative ephrin-receptor like DUF4298 PF14131.6 KXZ53023.1 - 0.2 11.6 0.0 0.45 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) SpoVAC_SpoVAEB PF03862.13 KXZ53023.1 - 0.35 11.1 6.2 8.1 6.8 0.8 2.5 2 0 0 2 2 2 0 SpoVAC/SpoVAEB sporulation membrane protein NCD3G PF07562.14 KXZ53023.1 - 2.5 8.1 9.6 1.5 8.9 1.4 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR RHH_6 PF16762.5 KXZ53023.1 - 3.3 8.4 5.8 28 5.4 0.3 3.4 3 1 0 3 3 3 0 Ribbon-helix-helix domain TNFR_c6 PF00020.18 KXZ53023.1 - 6.1 7.3 7.6 2.9 8.4 0.9 2.5 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region WD40 PF00400.32 KXZ53024.1 - 5.3e-11 42.9 0.3 0.64 11.0 0.0 7.8 9 0 0 9 9 9 2 WD domain, G-beta repeat DUF2891 PF11199.8 KXZ53024.1 - 0.01 14.8 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Phasin PF05597.11 KXZ53024.1 - 0.64 10.0 11.6 0.023 14.7 2.3 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SlyX PF04102.12 KXZ53024.1 - 1.8 9.2 17.7 16 6.2 1.4 5.3 4 0 0 4 4 4 0 SlyX TMF_DNA_bd PF12329.8 KXZ53024.1 - 5.9 7.0 32.8 0.13 12.3 0.1 5.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding NOA36 PF06524.12 KXZ53024.1 - 9.1 5.5 21.5 1.4 8.2 4.2 2.3 2 0 0 2 2 2 0 NOA36 protein HSP90 PF00183.18 KXZ53025.1 - 2.7e-238 792.1 22.4 2.7e-238 792.1 22.4 1.3 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 KXZ53025.1 - 1.8e-14 54.2 0.1 3.5e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXZ53025.1 - 3.7e-11 43.0 0.1 1.2e-10 41.3 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF740 PF05340.12 KXZ53025.1 - 1.5 7.5 6.0 0.63 8.7 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF740) DUF3847 PF12958.7 KXZ53025.1 - 3.4 7.9 7.8 1.9 8.7 4.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) Biotin_lipoyl PF00364.22 KXZ53026.1 - 7.5e-31 105.8 0.6 1.7e-15 56.6 0.1 2.1 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXZ53026.1 - 0.00036 20.3 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 KXZ53026.1 - 0.0025 18.5 0.3 0.47 11.2 0.1 2.5 2 1 0 2 2 2 1 HlyD family secretion protein QRPTase_N PF02749.16 KXZ53026.1 - 0.025 14.6 0.0 8.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain 2-oxoacid_dh PF00198.23 KXZ53027.1 - 1.1e-63 214.9 0.0 1.4e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Mannosyl_trans3 PF11051.8 KXZ53028.1 - 2.8e-40 138.4 0.0 2.4e-25 89.5 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative CAP59_mtransfer PF11735.8 KXZ53029.1 - 7.4e-56 189.5 0.0 8.9e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ArfGap PF01412.18 KXZ53030.1 - 2.4e-17 63.1 0.2 2.4e-17 63.1 0.2 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF1631 PF07793.11 KXZ53030.1 - 3.7 5.8 8.1 0.99 7.7 4.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1631) Glyco_transf_90 PF05686.12 KXZ53031.1 - 4.1e-07 29.3 0.0 9.2e-07 28.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 RRM_1 PF00076.22 KXZ53032.1 - 2.3e-34 117.0 0.0 1.6e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SF1-HH PF16275.5 KXZ53032.1 - 1.8e-25 89.5 1.0 4.1e-25 88.3 1.0 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain RRM_7 PF16367.5 KXZ53032.1 - 0.011 15.8 0.0 5.9 7.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Mito_carr PF00153.27 KXZ53035.1 - 1.7e-67 223.4 5.4 1.3e-23 82.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ACAS_N PF16177.5 KXZ53035.1 - 0.14 12.1 0.5 0.24 11.3 0.5 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Kinesin PF00225.23 KXZ53036.1 - 1.5e-87 293.7 0.0 2.2e-87 293.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ53036.1 - 4e-15 56.0 0.0 7.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KXZ53036.1 - 0.1 13.0 0.4 0.63 10.4 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF724 PF05266.14 KXZ53036.1 - 0.11 12.3 2.0 0.24 11.2 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF87 PF01935.17 KXZ53036.1 - 0.55 10.3 4.0 3.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain Pkinase PF00069.25 KXZ53037.1 - 2.1e-14 53.5 0.0 1.9e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53037.1 - 3.2e-10 39.7 0.0 4.3e-09 36.0 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase FAST_1 PF06743.15 KXZ53038.1 - 4.5e-05 23.3 0.0 0.088 12.8 0.0 3.0 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 TFIIS_M PF07500.14 KXZ53039.1 - 1.6e-30 105.9 0.0 2.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 KXZ53039.1 - 1e-06 28.7 0.1 2.3e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_L6 PF00347.23 KXZ53040.1 - 4.1e-36 123.5 4.0 9.2e-18 64.7 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 UBA_e1_thiolCys PF10585.9 KXZ53041.1 - 5.3e-55 187.1 0.0 7.2e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KXZ53041.1 - 4.6e-15 56.1 0.0 8.3e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fold domain ThiF PF00899.21 KXZ53041.1 - 4.8e-08 32.7 0.0 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Homez PF11569.8 KXZ53041.1 - 0.073 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez ThiF PF00899.21 KXZ53042.1 - 5e-35 121.0 0.1 7.3e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 ThiF family E1_FCCH PF16190.5 KXZ53042.1 - 2.3e-24 85.3 0.1 4.1e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KXZ53042.1 - 0.0076 16.4 0.1 0.02 15.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle adh_short PF00106.25 KXZ53042.1 - 0.076 12.5 1.9 0.45 10.0 2.0 2.0 1 1 1 2 2 2 0 short chain dehydrogenase Rhamno_transf PF11316.8 KXZ53042.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase ComFB PF10719.9 KXZ53042.1 - 0.19 11.9 0.1 0.36 11.0 0.1 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB APG9 PF04109.16 KXZ53043.1 - 1.1e-60 206.0 0.0 1.2e-40 140.0 0.0 2.2 1 1 1 2 2 2 2 Autophagy protein Apg9 ABC_membrane PF00664.23 KXZ53044.1 - 1.8e-13 50.8 0.0 2.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ53044.1 - 2.6e-07 31.2 0.0 3.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter FAST_1 PF06743.15 KXZ53045.1 - 1.4e-10 41.0 0.0 0.45 10.5 0.0 8.9 8 1 1 9 9 9 3 FAST kinase-like protein, subdomain 1 DDE_Tnp_IS66_C PF13817.6 KXZ53045.1 - 0.1 12.9 0.1 13 6.1 0.0 3.1 2 0 0 2 2 2 0 IS66 C-terminal element ABC_membrane PF00664.23 KXZ53046.1 - 1.7e-21 77.1 1.5 2.3e-21 76.6 1.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ53046.1 - 2.4e-14 54.0 0.2 2.9e-10 40.8 0.2 2.3 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KXZ53046.1 - 0.012 16.0 0.1 0.03 14.7 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 KXZ53046.1 - 0.023 14.5 0.1 2.3 8.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ53046.1 - 0.13 12.1 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KXZ53046.1 - 0.21 11.7 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_25 PF13481.6 KXZ53046.1 - 1.3 8.6 5.6 0.23 11.0 0.1 2.6 3 1 0 3 3 3 0 AAA domain US30 PF17624.2 KXZ53046.1 - 1.8 7.5 4.3 0.34 9.9 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function PG_binding_3 PF09374.10 KXZ53047.1 - 0.15 12.3 1.3 0.51 10.6 0.0 2.3 2 1 0 2 2 2 0 Predicted Peptidoglycan domain Trypan_PARP PF05887.11 KXZ53048.1 - 0.029 14.3 80.1 0.11 12.5 30.5 3.5 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) Lectin_C PF00059.21 KXZ53049.1 - 1.1e-12 48.7 4.4 1.9e-12 47.8 4.4 1.5 1 0 0 1 1 1 1 Lectin C-type domain RRM_1 PF00076.22 KXZ53050.1 - 5.1e-17 61.5 0.0 6.5e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ53050.1 - 0.06 13.0 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AP2 PF00847.20 KXZ53053.1 - 2.7e-09 37.1 4.3 3.3e-06 27.2 2.8 2.3 2 0 0 2 2 2 2 AP2 domain Response_reg PF00072.24 KXZ53054.1 - 4.6e-21 75.1 0.0 8.5e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain WD40 PF00400.32 KXZ53054.1 - 3.4e-14 53.0 6.9 0.0032 18.3 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Pkinase PF00069.25 KXZ53054.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Rhodanese PF00581.20 KXZ53056.1 - 1.5e-08 35.1 0.0 6.2e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain Cyclin_N PF00134.23 KXZ53057.1 - 1.2e-48 164.0 4.0 1.4e-47 160.6 1.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ53057.1 - 4.2e-25 88.1 1.2 7.8e-25 87.3 1.2 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF5552 PF17706.1 KXZ53057.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5552) GrpE PF01025.19 KXZ53058.1 - 1.7e-35 122.1 0.1 2.5e-35 121.6 0.1 1.2 1 0 0 1 1 1 1 GrpE Sigma70_ner PF04546.13 KXZ53058.1 - 0.0081 16.1 2.9 1 9.2 2.5 2.2 2 0 0 2 2 2 2 Sigma-70, non-essential region ASD2 PF08687.11 KXZ53058.1 - 0.011 15.3 1.2 0.015 14.9 1.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 CLZ PF16526.5 KXZ53058.1 - 0.056 13.8 1.5 0.12 12.8 1.5 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AIG2_2 PF13772.6 KXZ53059.1 - 5.6e-06 26.7 0.0 8.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KXZ53059.1 - 2.8e-05 24.7 0.1 3.7e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ChaC PF04752.12 KXZ53059.1 - 0.071 13.2 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 ChaC-like protein CBFD_NFYB_HMF PF00808.23 KXZ53060.1 - 2.9e-15 56.3 0.1 7.7e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KXZ53060.1 - 0.00057 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 CENP-W protein YchF-GTPase_C PF06071.13 KXZ53061.1 - 1.1e-40 137.7 0.6 7.7e-40 135.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXZ53061.1 - 7.1e-21 74.4 0.0 1.3e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ53061.1 - 4.6e-07 29.5 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KXZ53061.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KXZ53061.1 - 0.13 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KXZ53061.1 - 0.13 12.8 0.1 0.34 11.4 0.1 1.6 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 KXZ53061.1 - 0.14 12.2 0.0 3.5 7.7 0.0 2.7 1 1 0 1 1 1 0 Dynamin family Ank_4 PF13637.6 KXZ53062.1 - 2.6e-07 31.1 2.5 5 7.8 0.1 6.8 7 3 1 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ53062.1 - 2.1e-05 25.0 0.0 5.5 7.7 0.0 4.4 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) FR47 PF08445.10 KXZ53062.1 - 0.12 12.3 0.3 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 FR47-like protein FAD-oxidase_C PF02913.19 KXZ53063.1 - 2.4e-59 201.0 0.0 3.2e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXZ53063.1 - 7.9e-32 109.9 0.5 7.9e-32 109.9 0.5 2.3 2 0 0 2 2 2 1 FAD binding domain Lectin_C PF00059.21 KXZ53064.1 - 1.8e-12 47.9 2.9 3.2e-12 47.1 2.9 1.4 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 KXZ53065.1 - 0.013 16.2 0.0 0.024 15.4 0.0 1.3 1 0 0 1 1 1 0 Lectin C-type domain Kinesin PF00225.23 KXZ53067.1 - 2.5e-105 352.1 0.0 3.7e-105 351.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ53067.1 - 2.7e-20 72.8 0.0 6e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding YaeQ PF07152.12 KXZ53067.1 - 0.039 13.6 0.2 0.073 12.7 0.2 1.4 1 0 0 1 1 1 0 YaeQ protein SNCAIP_SNCA_bd PF16700.5 KXZ53067.1 - 0.43 10.3 2.7 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain AIG2_2 PF13772.6 KXZ53069.1 - 2.1e-06 28.0 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family NINJA_B PF16136.5 KXZ53069.1 - 0.31 11.4 6.9 4.1 7.8 0.4 2.4 2 0 0 2 2 2 0 Putative nuclear localisation signal Sugar_tr PF00083.24 KXZ53070.1 - 1.1e-37 130.0 18.6 4.2e-20 72.0 6.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXZ53070.1 - 5.5e-13 48.6 32.1 7.7e-13 48.1 27.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.8 KXZ53070.1 - 0.031 14.0 0.5 0.38 10.5 0.3 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Fic PF02661.18 KXZ53071.1 - 2.3e-20 73.3 0.0 4.5e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family Hint_2 PF13403.6 KXZ53072.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Hint domain UCR_Fe-S_N PF10399.9 KXZ53073.1 - 0.01 15.2 0.2 0.018 14.4 0.2 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF2627 PF11118.8 KXZ53073.1 - 0.18 12.4 1.3 0.53 10.9 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) DUF883 PF05957.13 KXZ53073.1 - 0.57 10.8 3.5 13 6.4 0.3 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ANAPC4_WD40 PF12894.7 KXZ53074.1 - 3.9e-16 59.1 0.3 0.01 16.1 0.0 6.1 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ53074.1 - 8.9e-09 35.8 14.3 0.13 13.2 0.0 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.11 KXZ53074.1 - 2.3e-07 30.9 0.0 0.58 10.0 0.0 4.3 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 KXZ53074.1 - 0.0051 16.8 4.7 18 5.2 1.1 4.8 3 2 0 3 3 3 1 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 KXZ53074.1 - 0.0096 14.0 3.7 1.6 6.6 0.0 3.8 2 1 2 4 4 4 2 IKI3 family DPPIV_N PF00930.21 KXZ53074.1 - 0.041 12.7 0.6 19 3.9 0.0 4.5 4 2 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 KXZ53074.1 - 0.061 13.3 5.1 12 6.0 0.1 4.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KXZ53074.1 - 0.13 12.0 0.9 54 3.6 0.0 4.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature FAD_binding_4 PF01565.23 KXZ53075.1 - 8.3e-24 83.9 0.1 1.8e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXZ53075.1 - 3e-19 69.9 0.0 1.5e-11 44.7 0.0 2.4 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase zf-C3HC4_3 PF13920.6 KXZ53076.1 - 0.00023 20.9 7.5 0.0003 20.6 7.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.14 KXZ53076.1 - 0.22 11.4 0.2 0.22 11.4 0.2 2.8 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-C3HC4_3 PF13920.6 KXZ53078.1 - 0.00055 19.7 7.5 0.00082 19.2 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.14 KXZ53078.1 - 2.9 7.8 10.5 0.56 10.1 0.4 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-C3HC4_3 PF13920.6 KXZ53079.1 - 0.0012 18.7 3.6 0.0018 18.1 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 KXZ53079.1 - 0.9 9.6 4.1 1.8 8.6 4.1 1.5 1 0 0 1 1 1 0 zinc-ribbons DUF212 PF02681.14 KXZ53080.1 - 4.9e-46 156.0 0.1 5.6e-46 155.8 0.1 1.0 1 0 0 1 1 1 1 Divergent PAP2 family WSN PF02206.18 KXZ53080.1 - 0.078 12.9 0.1 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function PAP2 PF01569.21 KXZ53080.1 - 0.16 11.7 5.7 3.2 7.5 0.1 2.5 2 1 0 2 2 2 0 PAP2 superfamily AMP-binding PF00501.28 KXZ53081.1 - 6.1e-11 41.6 0.0 2.1e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXZ53081.1 - 0.015 15.6 0.2 0.05 14.0 0.2 2.0 1 1 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KXZ53082.1 - 2.2e-13 50.3 0.0 3.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ53082.1 - 1e-12 48.5 0.0 3.3e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ53082.1 - 2.7e-10 40.8 0.0 0.00038 21.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ53082.1 - 3.5e-09 36.4 0.0 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXZ53082.1 - 1.1e-07 32.5 0.0 0.00067 20.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ53082.1 - 0.0022 17.8 0.0 0.0064 16.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PRIMA1 PF16101.5 KXZ53082.1 - 2.1 8.4 7.0 3.6 7.7 7.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribosomal_S27e PF01667.17 KXZ53083.1 - 5.1e-29 99.8 6.0 6.2e-29 99.5 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 KXZ53083.1 - 0.0065 16.2 1.6 0.01 15.5 1.6 1.4 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_12 PF11331.8 KXZ53083.1 - 2.2 8.2 9.3 3.2 7.7 5.4 2.7 1 1 1 2 2 2 0 Probable zinc-ribbon domain Dynamin_N PF00350.23 KXZ53084.1 - 1.3e-30 106.6 0.0 2.2e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXZ53084.1 - 7.8e-05 22.7 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 KXZ53084.1 - 0.0038 16.5 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region AIG1 PF04548.16 KXZ53084.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 AIG1 family FtsJ PF01728.19 KXZ53085.1 - 8.7e-57 192.1 0.0 1.6e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 KXZ53085.1 - 4.3e-48 163.8 16.7 4.3e-48 163.8 16.7 3.1 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 KXZ53085.1 - 5.1e-37 127.2 0.3 5.1e-37 127.2 0.3 5.2 5 2 0 5 5 5 1 Domain of unknown function (DUF3381) DUF2477 PF10631.9 KXZ53085.1 - 0.047 14.4 0.2 0.19 12.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) S8_pro-domain PF16470.5 KXZ53085.1 - 1 10.2 4.9 0.74 10.6 2.0 2.3 2 0 0 2 2 2 0 Peptidase S8 pro-domain Serglycin PF04360.12 KXZ53085.1 - 2.1 8.3 7.7 0.35 10.8 2.8 2.1 2 0 0 2 2 2 0 Serglycin Pkinase PF00069.25 KXZ53086.1 - 7.8e-44 150.0 0.0 1.1e-43 149.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53086.1 - 1.4e-20 73.7 0.0 2.3e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ53086.1 - 1.6e-06 27.7 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ53086.1 - 0.00079 18.3 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ53086.1 - 0.13 12.2 0.1 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4148 PF13663.6 KXZ53086.1 - 2.1 8.6 14.0 1.1 9.4 8.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) RNA_pol_Rpb1_5 PF04998.17 KXZ53087.1 - 4.9e-85 285.2 0.0 6.9e-85 284.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXZ53087.1 - 1.5e-53 181.5 0.0 2.7e-53 180.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KXZ53087.1 - 3.1e-29 102.3 0.2 3.4e-25 89.0 0.0 2.9 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KXZ53087.1 - 5.6e-28 97.8 0.0 9.5e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXZ53087.1 - 5.6e-19 68.1 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.12 KXZ53087.1 - 3 6.0 30.5 0.071 11.3 4.8 2.1 2 0 0 2 2 2 0 Nop14-like family Mak_N_cap PF18085.1 KXZ53088.1 - 0.91 10.6 3.3 1.2 10.2 0.4 2.8 2 0 0 2 2 2 0 Maltokinase N-terminal cap domain Ribosomal_L7Ae PF01248.26 KXZ53089.1 - 1.6e-23 82.2 0.7 3.3e-23 81.2 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXZ53089.1 - 0.00047 20.2 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 p25-alpha PF05517.12 KXZ53090.1 - 0.00018 21.7 0.0 0.0006 20.0 0.0 1.8 1 1 0 1 1 1 1 p25-alpha LRR_6 PF13516.6 KXZ53093.1 - 1.2e-20 71.7 18.2 0.0076 16.2 0.0 10.3 10 0 0 10 10 10 7 Leucine Rich repeat LRR_4 PF12799.7 KXZ53093.1 - 5.1e-06 26.7 0.0 39 4.9 0.0 6.1 5 2 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ53093.1 - 0.00036 20.2 2.5 0.42 10.4 0.0 5.6 8 0 0 8 8 8 1 Leucine rich repeat PKD_channel PF08016.12 KXZ53094.1 - 8.4e-08 31.3 8.9 1.4e-07 30.6 8.9 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KXZ53094.1 - 6.2e-07 28.9 14.1 1.3e-06 27.8 14.1 1.5 1 0 0 1 1 1 1 Ion transport protein PKcGMP_CC PF16808.5 KXZ53094.1 - 0.016 15.1 1.0 0.039 13.8 1.0 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TetR_C_6 PF13977.6 KXZ53094.1 - 2.1 8.6 7.1 0.54 10.5 0.1 3.2 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal MIF4G PF02854.19 KXZ53095.1 - 3.1e-35 121.7 0.2 5.3e-35 121.0 0.2 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KXZ53095.1 - 5.1e-13 49.0 0.1 3.3e-12 46.4 0.0 2.4 3 0 0 3 3 3 1 MA3 domain eIF_4G1 PF12152.8 KXZ53095.1 - 0.033 14.4 0.0 0.09 13.0 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Pkinase PF00069.25 KXZ53096.1 - 2.3e-35 122.2 0.0 4.2e-17 62.4 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53096.1 - 7.3e-08 32.0 0.0 0.0014 17.9 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Exo_endo_phos PF03372.23 KXZ53097.1 - 1e-10 41.5 0.0 2.5e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cytochrom_C PF00034.21 KXZ53098.1 - 1.4e-12 48.6 0.4 2.1e-12 48.0 0.4 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KXZ53098.1 - 9e-08 32.3 4.2 3.2e-07 30.6 4.2 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KXZ53098.1 - 0.0004 20.1 0.2 0.002 17.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain KTSC PF13619.6 KXZ53098.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 KTSC domain Kinesin PF00225.23 KXZ53100.1 - 2.1e-117 391.8 0.0 2.1e-117 391.8 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ53100.1 - 7.3e-24 84.4 0.4 2.3e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 KXZ53100.1 - 0.0007 19.8 9.3 0.0007 19.8 9.3 2.9 2 1 1 3 3 3 1 Kinesin-associated Intein_splicing PF14890.6 KXZ53100.1 - 0.8 9.7 2.8 4.9 7.1 2.9 2.5 1 1 0 1 1 1 0 Intein splicing domain OGG_N PF07934.12 KXZ53100.1 - 2.1 8.5 4.6 4.2 7.5 3.2 2.3 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain SLATT_5 PF18160.1 KXZ53100.1 - 9.5 5.5 10.7 0.041 13.2 1.2 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 mTERF PF02536.14 KXZ53101.1 - 1.6e-07 30.6 0.0 0.0024 16.9 0.0 2.5 1 1 1 2 2 2 2 mTERF Sigma70_r3 PF04539.16 KXZ53101.1 - 0.02 15.0 0.1 3.4 7.8 0.1 2.9 3 0 0 3 3 3 0 Sigma-70 region 3 MarR_2 PF12802.7 KXZ53101.1 - 0.027 14.4 10.1 1.6 8.6 0.1 4.6 4 1 1 5 5 5 0 MarR family IF2_N PF04760.15 KXZ53101.1 - 0.13 12.1 0.2 1.9 8.3 0.0 2.5 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region HTH_23 PF13384.6 KXZ53101.1 - 0.25 11.2 3.7 15 5.5 0.0 3.6 4 0 0 4 4 4 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KXZ53101.1 - 0.41 10.5 0.1 0.41 10.5 0.1 3.4 4 1 0 4 4 4 0 AsnC-type helix-turn-helix domain Sec16_C PF12931.7 KXZ53102.1 - 1.8e-09 37.7 0.7 2.9e-06 27.2 0.7 2.9 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KXZ53102.1 - 1.3e-07 31.5 0.1 2.7e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) ANAPC4_WD40 PF12894.7 KXZ53102.1 - 9e-05 22.7 1.4 0.21 11.9 0.1 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ53102.1 - 0.00011 22.9 17.7 0.021 15.7 0.2 5.9 5 1 1 6 6 6 2 WD domain, G-beta repeat Sec16 PF12932.7 KXZ53102.1 - 0.0062 17.1 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Prp18 PF02840.15 KXZ53102.1 - 0.078 13.0 0.1 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Prp18 domain FANCI_S2 PF14676.6 KXZ53102.1 - 0.13 12.5 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 FANCI solenoid 2 TTL PF03133.15 KXZ53103.1 - 2.1e-16 59.9 0.0 2.9e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family tRNA-synt_1b PF00579.25 KXZ53104.1 - 1.8e-30 106.3 0.0 6e-17 61.9 0.0 2.6 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) Secretin_N PF03958.17 KXZ53104.1 - 0.16 12.4 0.0 41 4.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain LRR_6 PF13516.6 KXZ53105.1 - 3.7e-09 35.9 8.0 0.0012 18.7 0.2 5.8 6 0 0 6 6 4 2 Leucine Rich repeat EF-hand_7 PF13499.6 KXZ53105.1 - 1.1e-08 35.4 0.2 1.4e-07 31.9 0.3 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ53105.1 - 3.1e-07 29.5 1.2 0.0072 15.8 0.4 2.6 2 0 0 2 2 2 2 EF hand p25-alpha PF05517.12 KXZ53105.1 - 4.9e-07 30.0 0.0 3.6e-05 24.0 0.0 2.9 2 1 0 2 2 2 1 p25-alpha EF-hand_8 PF13833.6 KXZ53105.1 - 1.3e-06 28.2 0.2 0.051 13.4 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ53105.1 - 2.2e-06 27.1 0.2 0.041 13.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KXZ53105.1 - 0.0051 16.2 0.2 0.37 10.4 0.1 2.4 2 0 0 2 2 2 1 EF hand FapA PF03961.13 KXZ53105.1 - 0.0053 15.4 0.4 0.52 8.9 0.0 2.9 2 1 1 3 3 3 1 Flagellar Assembly Protein A Trns_repr_metal PF02583.17 KXZ53105.1 - 0.007 16.7 7.1 0.017 15.5 1.0 3.3 3 0 0 3 3 3 1 Metal-sensitive transcriptional repressor LRR_4 PF12799.7 KXZ53105.1 - 0.039 14.4 0.1 0.26 11.8 0.1 2.4 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF3584 PF12128.8 KXZ53105.1 - 0.13 9.7 12.9 0.22 9.0 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin PF00804.25 KXZ53105.1 - 0.22 11.2 2.6 1.5 8.5 0.1 2.4 1 1 1 2 2 2 0 Syntaxin BshC PF10079.9 KXZ53105.1 - 0.61 8.8 2.9 0.28 9.9 0.1 1.7 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC DUF948 PF06103.11 KXZ53105.1 - 0.75 10.1 9.6 0.72 10.1 0.4 3.7 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) DUF1690 PF07956.11 KXZ53105.1 - 0.9 10.0 6.3 0.35 11.3 1.3 2.8 1 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Fib_alpha PF08702.10 KXZ53105.1 - 1 9.5 5.3 2.5 8.3 0.6 2.8 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family GOLGA2L5 PF15070.6 KXZ53105.1 - 1.2 7.7 10.9 2.3 6.8 2.6 2.3 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Baculo_PEP_C PF04513.12 KXZ53105.1 - 1.6 8.8 10.9 3.7 7.6 0.1 3.9 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KXZ53105.1 - 3 7.9 5.7 7.2 6.7 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) CCDC144C PF14915.6 KXZ53105.1 - 3.6 6.6 7.9 1.1 8.3 2.9 2.3 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region Fez1 PF06818.15 KXZ53105.1 - 5.8 7.3 7.7 56 4.1 7.6 2.4 1 1 0 1 1 1 0 Fez1 RmuC PF02646.16 KXZ53105.1 - 6.9 5.7 8.1 2.2 7.3 0.6 2.8 2 1 0 3 3 3 0 RmuC family NPV_P10 PF05531.12 KXZ53105.1 - 7.7 7.1 10.5 24 5.5 0.2 4.1 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Lzipper-MIP1 PF14389.6 KXZ53105.1 - 8.7 6.7 6.7 0.7 10.2 0.3 2.5 3 0 0 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 Spc7 PF08317.11 KXZ53105.1 - 10 4.9 6.1 17 4.1 4.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Dynamin_N PF00350.23 KXZ53106.1 - 1.5e-12 47.9 0.0 3.9e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXZ53106.1 - 1.7e-06 28.1 0.0 9.7e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RHD3 PF05879.12 KXZ53106.1 - 0.019 13.1 0.0 2.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) Gtr1_RagA PF04670.12 KXZ53106.1 - 0.03 13.7 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXZ53106.1 - 0.2 11.2 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Apolipoprotein PF01442.18 KXZ53106.1 - 0.38 10.6 15.1 0.11 12.4 4.3 3.5 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain TPR_MLP1_2 PF07926.12 KXZ53106.1 - 0.49 10.5 3.5 1.2 9.3 1.6 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.6 KXZ53106.1 - 7.2 6.7 6.4 6.5 6.9 1.6 3.3 4 0 0 4 4 4 0 Nucleoporin complex subunit 54 CCDC66 PF15236.6 KXZ53107.1 - 0.0015 18.3 6.5 0.0015 18.3 6.5 3.7 5 0 0 5 5 5 1 Coiled-coil domain-containing protein 66 RHSP PF07999.11 KXZ53109.1 - 0.003 16.4 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon hot spot protein ProRS-C_1 PF09180.11 KXZ53109.1 - 0.031 14.5 0.0 5.3 7.3 0.0 2.3 1 1 1 2 2 2 0 Prolyl-tRNA synthetase, C-terminal RNA_helicase PF00910.22 KXZ53109.1 - 0.039 14.3 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KXZ53109.1 - 0.15 12.4 0.0 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Serglycin PF04360.12 KXZ53110.1 - 0.25 11.3 1.6 1.6 8.7 0.5 2.3 2 0 0 2 2 2 0 Serglycin CBM_1 PF00734.18 KXZ53110.1 - 2 8.5 18.6 1e+02 3.0 18.6 3.3 1 1 0 1 1 1 0 Fungal cellulose binding domain ABC_tran PF00005.27 KXZ53111.1 - 2.6e-49 167.2 0.0 1.4e-26 93.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KXZ53111.1 - 8.9e-35 120.4 23.7 1.9e-17 63.4 1.6 3.8 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 KXZ53111.1 - 7.3e-21 75.3 0.0 2.5e-07 30.8 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KXZ53111.1 - 0.0034 17.0 1.8 0.71 9.5 0.3 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KXZ53111.1 - 0.0045 17.5 3.6 0.15 12.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXZ53111.1 - 0.0059 16.3 1.9 0.072 12.8 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXZ53111.1 - 0.028 14.3 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 KXZ53111.1 - 0.043 14.0 0.1 1.6 9.0 0.1 3.5 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit MukB PF04310.12 KXZ53111.1 - 0.073 12.9 1.7 4 7.2 0.2 2.3 2 0 0 2 2 2 0 MukB N-terminal SMC_N PF02463.19 KXZ53111.1 - 0.15 11.5 0.0 9 5.7 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Clc-like PF07062.12 KXZ53111.1 - 0.15 11.5 0.1 0.35 10.3 0.1 1.5 1 0 0 1 1 1 0 Clc-like AAA_15 PF13175.6 KXZ53111.1 - 0.26 10.9 0.0 0.5 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KXZ53111.1 - 4.6 7.6 9.0 8.5 6.7 0.1 4.4 4 0 0 4 4 4 0 AAA ATPase domain Clathrin PF00637.20 KXZ53112.1 - 6.4e-10 39.1 0.0 2e-07 30.9 0.0 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KXZ53112.1 - 4.6e-05 23.6 0.0 0.00072 19.8 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXZ53112.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 WD40-like domain WD40 PF00400.32 KXZ53112.1 - 0.0091 16.8 0.0 0.029 15.2 0.0 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat Mcl1_mid PF12341.8 KXZ53112.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region TPR_2 PF07719.17 KXZ53112.1 - 0.16 12.2 0.7 11 6.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Radical_SAM PF04055.21 KXZ53113.1 - 6.1e-18 65.8 0.0 8.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXZ53113.1 - 9e-17 61.6 0.0 1.4e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXZ53113.1 - 1.2e-10 41.5 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain RB_B PF01857.20 KXZ53115.1 - 3.9e-08 33.4 0.0 6.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Glyco_hydro81C PF17652.1 KXZ53116.1 - 2.1e-128 428.4 0.1 3e-83 280.0 0.0 2.4 2 1 0 2 2 2 2 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KXZ53116.1 - 2.5e-38 132.1 0.0 2.5e-22 79.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain Ion_trans PF00520.31 KXZ53117.1 - 7.3e-21 74.5 11.2 1e-20 74.0 11.2 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KXZ53117.1 - 2.2e-14 53.3 0.0 6e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SlyX PF04102.12 KXZ53117.1 - 0.2 12.3 6.3 0.26 11.9 0.0 2.7 2 0 0 2 2 2 0 SlyX SET PF00856.28 KXZ53118.1 - 7.9e-09 36.1 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 SET domain Methyltransf_21 PF05050.12 KXZ53120.1 - 6.2e-11 42.6 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain NTP_transf_2 PF01909.23 KXZ53121.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyltransferase domain OAS1_C PF10421.9 KXZ53121.1 - 0.091 12.2 0.2 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Peptidase_M48 PF01435.18 KXZ53123.1 - 5.4e-28 98.1 0.9 9.5e-18 64.7 0.3 2.2 2 0 0 2 2 2 2 Peptidase family M48 IHABP4_N PF16174.5 KXZ53123.1 - 0.014 16.1 0.4 0.027 15.1 0.4 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF5560 PF17715.1 KXZ53123.1 - 0.058 12.8 1.9 0.74 9.2 1.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5560) PepSY_2 PF13670.6 KXZ53123.1 - 0.36 10.8 6.1 9.9 6.2 0.0 3.0 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Beta_helix PF13229.6 KXZ53124.1 - 5.5e-15 55.6 0.0 6.8e-09 35.8 0.2 2.4 2 0 0 2 2 2 2 Right handed beta helix region Ank_2 PF12796.7 KXZ53125.1 - 0.11 13.1 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Phosphorylase PF00343.20 KXZ53126.1 - 0 1064.9 0.0 0 1064.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase ACT PF01842.25 KXZ53126.1 - 0.00033 20.4 0.1 0.00076 19.2 0.1 1.7 1 0 0 1 1 1 1 ACT domain Acyl-CoA_ox_N PF14749.6 KXZ53126.1 - 0.0071 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal DUF3437 PF11919.8 KXZ53126.1 - 0.11 12.5 0.1 0.46 10.4 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Pkinase_Tyr PF07714.17 KXZ53128.1 - 2.6e-21 76.1 0.0 1.9e-14 53.6 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ53128.1 - 2.6e-19 69.6 0.0 4.8e-17 62.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ53128.1 - 0.0007 19.0 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ53128.1 - 0.059 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ53128.1 - 0.072 11.9 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Lectin_C PF00059.21 KXZ53129.1 - 1.7e-14 54.5 0.0 1.9e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Lectin C-type domain Ntox22 PF15527.6 KXZ53129.1 - 0.03 14.4 0.3 0.053 13.6 0.3 1.4 1 0 0 1 1 1 0 Bacterial toxin 22 DUF3707 PF12499.8 KXZ53130.1 - 9.9e-13 48.9 0.2 1.3e-12 48.4 0.2 1.1 1 0 0 1 1 1 1 Pherophorin Ank_2 PF12796.7 KXZ53131.1 - 3.6e-32 110.8 0.3 1.5e-11 44.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53131.1 - 2.5e-31 107.6 6.0 6.4e-10 39.4 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ53131.1 - 5.5e-28 96.1 9.1 5.7e-06 26.5 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXZ53131.1 - 9.3e-25 86.4 4.3 1.4e-09 38.1 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53131.1 - 4.1e-24 82.0 1.0 4.8e-05 23.4 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 KXZ53132.1 - 5e-74 244.9 3.1 1.3e-17 64.2 0.0 5.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ53132.1 - 4.6e-56 186.1 8.4 1.5e-12 47.5 0.3 8.1 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ53132.1 - 6.3e-51 170.1 2.0 1.3e-11 44.7 0.0 8.0 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KXZ53132.1 - 2.4e-50 166.8 22.2 6e-08 32.8 0.2 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 KXZ53132.1 - 1.1e-45 148.3 6.0 7.4e-06 25.9 0.0 9.9 10 1 0 10 10 10 8 Ankyrin repeat GATase_7 PF13537.6 KXZ53132.1 - 0.00026 20.9 0.0 1.1 9.1 0.0 4.3 3 2 2 5 5 5 1 Glutamine amidotransferase domain Arm-DNA-bind_3 PF13356.6 KXZ53132.1 - 0.002 18.5 1.8 1.6 9.1 0.1 4.6 4 0 0 4 4 4 1 Arm DNA-binding domain DUF1843 PF08898.10 KXZ53132.1 - 0.051 14.1 1.9 34 5.0 0.0 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) Tom5 PF10642.9 KXZ53133.1 - 0.47 10.5 3.5 2.2 8.4 2.2 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Sec10 PF07393.11 KXZ53134.1 - 4.3e-27 94.9 0.0 4.9e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Sec10 PF07393.11 KXZ53135.1 - 6.1e-27 94.4 0.0 8.1e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 APG17 PF04108.12 KXZ53135.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF2203 PF09969.9 KXZ53135.1 - 0.22 12.3 4.0 1.5 9.5 1.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ALIX_LYPXL_bnd PF13949.6 KXZ53135.1 - 0.5 9.6 4.3 1 8.6 4.3 1.6 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Ank_2 PF12796.7 KXZ53136.1 - 0.0021 18.6 0.0 0.003 18.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ53136.1 - 0.0048 17.2 0.0 0.014 15.7 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF842 PF05811.13 KXZ53137.1 - 5.5e-34 116.7 8.8 6.2e-34 116.5 8.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Vicilin_N PF04702.12 KXZ53137.1 - 0.082 12.7 8.8 0.12 12.3 8.7 1.4 1 1 0 1 1 1 0 Vicilin N terminal region Flavodoxin_1 PF00258.25 KXZ53138.1 - 2.1e-37 128.5 0.0 4.6e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KXZ53138.1 - 2.8e-14 53.2 0.0 4.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXZ53138.1 - 6.3e-08 33.2 0.0 0.071 13.8 0.7 3.6 2 1 1 3 3 3 2 Oxidoreductase NAD-binding domain PAT1 PF09770.9 KXZ53138.1 - 0.48 8.6 17.7 0.72 8.1 17.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF45 PF01863.17 KXZ53138.1 - 2.7 8.0 4.3 5.2 7.0 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Rtf2 PF04641.12 KXZ53138.1 - 5.3 6.3 7.2 8.4 5.7 7.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Ndc1_Nup PF09531.10 KXZ53138.1 - 5.8 5.5 8.7 8.4 5.0 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 KXZ53138.1 - 6.7 6.7 6.5 12 5.9 6.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 KXZ53138.1 - 8.1 5.3 8.8 11 4.8 8.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 KXZ53138.1 - 9.5 4.2 6.7 13 3.7 6.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Guanylate_cyc PF00211.20 KXZ53141.1 - 7.4e-55 185.4 0.0 1.4e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PIF1 PF05970.14 KXZ53142.1 - 1.7e-11 44.0 0.0 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KXZ53142.1 - 0.00018 21.8 0.0 0.00018 21.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXZ53142.1 - 0.00056 20.3 1.5 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 KXZ53142.1 - 0.0018 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_11 PF13086.6 KXZ53142.1 - 0.0033 17.2 0.3 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXZ53142.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD-helicase PF00580.21 KXZ53142.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 KXZ53142.1 - 0.01 14.9 0.2 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 KXZ53142.1 - 0.025 14.9 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KXZ53142.1 - 0.037 12.8 2.3 0.37 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXZ53142.1 - 0.044 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KXZ53142.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KXZ53142.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DEAD PF00270.29 KXZ53142.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 KXZ53142.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MobB PF03205.14 KXZ53142.1 - 0.21 11.5 0.9 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CheZ PF04344.13 KXZ53142.1 - 1.1 9.1 3.3 1.7 8.5 3.3 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Guanylate_cyc PF00211.20 KXZ53144.1 - 1.8e-24 86.4 0.0 2.5e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ53145.1 - 1.2e-30 106.5 0.0 1.8e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain KH_8 PF17903.1 KXZ53147.1 - 0.00011 22.2 0.1 0.0002 21.4 0.1 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KXZ53147.1 - 0.0083 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 KH domain Pkinase PF00069.25 KXZ53148.1 - 1e-27 97.2 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53148.1 - 6.1e-16 58.5 0.0 7.2e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ53148.1 - 1.7e-08 33.7 0.1 2.2e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ53148.1 - 0.0006 19.8 0.0 0.00096 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glutaredoxin PF00462.24 KXZ53150.1 - 1.2e-16 60.7 0.1 1.8e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KXZ53150.1 - 0.00016 21.6 0.0 0.00034 20.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 KXZ53150.1 - 0.00071 19.9 0.0 0.00084 19.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.6 KXZ53150.1 - 0.0032 17.3 0.0 0.004 16.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 KXZ53150.1 - 0.02 15.1 0.4 1.7 8.8 0.4 2.1 1 1 0 2 2 2 0 Thioredoxin DUF953 PF06110.11 KXZ53150.1 - 0.042 13.5 0.0 0.061 12.9 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DSBA PF01323.20 KXZ53150.1 - 0.049 13.4 2.2 0.27 11.0 0.2 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 KXZ53150.1 - 0.13 12.7 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 KXZ53150.1 - 0.16 12.4 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glyco_transf_90 PF05686.12 KXZ53151.1 - 2e-32 112.6 0.0 3.4e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 AP2 PF00847.20 KXZ53152.1 - 5.8e-08 32.8 0.1 9.9e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 AP2 domain Gluconate_2-dh3 PF13618.6 KXZ53152.1 - 0.07 13.4 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Pex14_N PF04695.13 KXZ53152.1 - 0.1 13.3 0.6 0.15 12.7 0.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF658 PF04936.12 KXZ53152.1 - 0.14 11.9 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) MCM_OB PF17207.3 KXZ53156.1 - 1.7e-17 63.5 0.0 6.6e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_N PF14551.6 KXZ53156.1 - 1.9e-12 47.7 0.1 2.8e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 MCM N-terminal domain MCM PF00493.23 KXZ53157.1 - 4.6e-97 323.5 0.0 7.3e-97 322.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KXZ53157.1 - 4.6e-28 97.5 0.8 1.1e-27 96.3 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KXZ53157.1 - 4.1e-11 42.8 0.1 7.4e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KXZ53157.1 - 4.3e-07 29.5 0.0 2.7e-06 26.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXZ53157.1 - 2.6e-05 24.1 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ53157.1 - 8.6e-05 22.5 0.0 0.00032 20.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXZ53157.1 - 0.039 13.7 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain LRR_6 PF13516.6 KXZ53158.1 - 4.4e-08 32.5 15.3 0.81 9.9 0.0 7.6 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 KXZ53158.1 - 1.5e-07 31.6 0.9 0.11 13.0 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ53158.1 - 1.5e-05 24.8 0.2 12 6.9 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 KXZ53158.1 - 9.4e-05 22.1 6.5 0.11 12.3 0.1 5.7 5 1 0 5 5 5 2 Leucine rich repeat Helicase_C PF00271.31 KXZ53159.1 - 4.4e-28 97.9 0.0 7.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ53159.1 - 3.9e-21 75.6 0.0 6.3e-13 48.9 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C_2 PF13307.6 KXZ53159.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DnaJ PF00226.31 KXZ53160.1 - 2.3e-09 37.2 0.0 5.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain NPR3 PF03666.13 KXZ53160.1 - 0.45 9.2 10.5 0.58 8.9 10.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 KXZ53160.1 - 0.53 10.2 19.8 0.085 12.8 15.6 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 KXZ53160.1 - 0.55 8.4 13.3 0.73 8.1 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 KXZ53160.1 - 0.59 8.8 2.5 0.68 8.5 2.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 KXZ53160.1 - 0.61 8.5 3.4 0.73 8.3 3.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.9 KXZ53160.1 - 0.8 8.5 5.4 1 8.1 5.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MDM10 PF12519.8 KXZ53160.1 - 0.86 8.4 4.9 1.1 8.0 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Plasmodium_Vir PF05795.11 KXZ53160.1 - 1.2 8.5 4.0 1.6 8.1 4.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 KXZ53160.1 - 1.6 7.4 15.2 2.4 6.8 15.2 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 KXZ53160.1 - 2 7.1 13.1 3.4 6.3 11.7 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 KXZ53160.1 - 2.1 8.1 12.3 3.5 7.4 12.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 KXZ53160.1 - 3.8 8.1 18.2 0.19 12.4 12.0 2.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLC12 PF03522.15 KXZ53160.1 - 4.5 6.2 8.0 6.3 5.7 8.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 KXZ53160.1 - 6.2 5.9 6.9 0.87 8.7 2.4 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Hid1 PF12722.7 KXZ53160.1 - 7.6 4.5 10.1 11 4.1 10.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein APH PF01636.23 KXZ53162.1 - 4e-07 30.2 1.3 0.011 15.7 0.3 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KXZ53162.1 - 0.14 11.4 0.0 1 8.5 0.0 1.9 1 1 1 2 2 2 0 Fructosamine kinase FAP PF07174.11 KXZ53163.1 - 0.89 8.9 26.4 2 7.8 26.4 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Sulfotransfer_2 PF03567.14 KXZ53164.1 - 0.012 15.5 0.2 0.084 12.8 0.0 2.2 3 0 0 3 3 3 0 Sulfotransferase family MscS_porin PF12795.7 KXZ53164.1 - 0.033 13.7 0.3 0.08 12.5 0.3 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain CN_hydrolase PF00795.22 KXZ53165.1 - 2.5e-43 148.3 0.0 1e-41 143.0 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 KXZ53166.1 - 0.011 15.1 0.0 0.051 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Cyclin_N PF00134.23 KXZ53170.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Trns_repr_metal PF02583.17 KXZ53170.1 - 1.6 9.2 6.5 5.1 7.5 6.5 1.9 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Hemerythrin PF01814.23 KXZ53171.1 - 5.4e-13 49.7 4.7 1e-12 48.8 4.7 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2408 PF10303.9 KXZ53171.1 - 0.0035 17.9 0.0 0.0051 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) Rad51 PF08423.11 KXZ53172.1 - 5.2e-104 347.0 0.0 6.7e-104 346.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXZ53172.1 - 6e-11 42.3 0.1 9.4e-11 41.7 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KXZ53172.1 - 1.7e-06 27.5 0.0 3.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KXZ53172.1 - 2.6e-06 27.1 0.2 4.9e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KXZ53172.1 - 0.011 16.3 1.0 0.011 16.3 1.0 2.3 2 1 0 2 2 2 0 Helix-hairpin-helix domain DnaB_C PF03796.15 KXZ53172.1 - 0.034 13.5 0.1 0.75 9.1 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KXZ53172.1 - 0.036 13.8 0.0 0.098 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain HIT PF01230.23 KXZ53172.1 - 0.11 13.2 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 HIT domain HTH_19 PF12844.7 KXZ53172.1 - 0.15 12.1 0.0 0.97 9.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MatE PF01554.18 KXZ53173.1 - 9.8e-44 148.8 12.4 7.7e-25 87.4 3.2 2.5 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXZ53173.1 - 0.0065 16.5 16.1 0.058 13.5 1.0 2.8 2 0 0 2 2 2 2 Polysaccharide biosynthesis C-terminal domain Methyltransf_16 PF10294.9 KXZ53174.1 - 1.5e-13 50.9 0.0 6.9e-12 45.4 0.0 2.5 3 0 0 3 3 3 1 Lysine methyltransferase PrmA PF06325.13 KXZ53174.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXZ53174.1 - 0.063 14.0 0.0 0.92 10.3 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Trypan_PARP PF05887.11 KXZ53175.1 - 4.3e-10 39.7 125.4 0.00033 20.7 14.8 5.3 4 1 1 5 5 5 4 Procyclic acidic repetitive protein (PARP) Lectin_C PF00059.21 KXZ53175.1 - 7.4e-07 29.9 39.7 0.41 11.4 0.3 9.2 5 5 5 10 10 10 4 Lectin C-type domain MIT_LIKE_ACTX PF17556.2 KXZ53175.1 - 0.024 15.2 15.7 17 6.1 0.4 4.7 4 0 0 4 4 4 0 MIT-like atracotoxin family DFRP_C PF16543.5 KXZ53178.1 - 5.5e-13 49.2 5.5 5.5e-13 49.2 5.5 3.7 4 2 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KXZ53178.1 - 3.5e-05 23.5 12.3 0.00016 21.4 3.0 2.9 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXZ53178.1 - 0.00016 21.6 21.6 0.0051 16.8 8.1 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 KXZ53178.1 - 0.00024 21.3 0.6 0.065 13.5 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH PF00642.24 KXZ53178.1 - 0.00043 20.1 10.4 0.0017 18.2 1.5 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXZ53178.1 - 0.0018 19.0 19.1 0.2 12.4 7.7 4.0 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 KXZ53178.1 - 0.26 11.8 13.7 1.3 9.6 0.3 2.5 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Lustrin_cystein PF14625.6 KXZ53178.1 - 0.5 10.8 2.7 2.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Lectin_C PF00059.21 KXZ53179.1 - 0.00018 22.2 1.0 0.49 11.2 0.1 3.3 2 1 1 3 3 3 3 Lectin C-type domain Trypan_PARP PF05887.11 KXZ53180.1 - 1.5e-05 25.0 27.3 3e-05 24.0 27.3 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 KXZ53181.1 - 0.21 11.5 106.4 0.65 10.0 38.1 3.3 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) Lectin_C PF00059.21 KXZ53181.1 - 2 9.2 10.2 1.1 10.1 0.4 3.6 2 2 2 4 4 4 0 Lectin C-type domain Tocopherol_cycl PF14249.6 KXZ53182.1 - 5.6e-110 367.6 2.4 6.6e-110 367.4 2.4 1.0 1 0 0 1 1 1 1 Tocopherol cyclase zf-CCHC PF00098.23 KXZ53183.1 - 5.1e-17 61.1 42.8 1.8e-06 27.8 1.7 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 KXZ53183.1 - 1.4e-06 27.9 32.1 0.0063 16.2 0.4 5.4 4 1 1 5 5 5 4 Zinc knuckle dCMP_cyt_deam_1 PF00383.23 KXZ53183.1 - 0.00099 19.0 0.4 0.0028 17.5 0.4 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NYD-SP12_N PF15015.6 KXZ53183.1 - 0.35 9.2 0.3 0.5 8.7 0.3 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal zf-CCHC_2 PF13696.6 KXZ53183.1 - 2.5 8.0 31.8 0.9 9.4 2.3 5.5 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_3 PF13917.6 KXZ53183.1 - 8.4 6.5 25.7 3.6 7.6 1.1 5.2 4 2 1 5 5 5 0 Zinc knuckle DUF5585 PF17823.1 KXZ53185.1 - 2.3 7.1 8.6 0.78 8.6 2.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5585) Porin_3 PF01459.22 KXZ53186.1 - 1.9e-30 106.2 3.1 2.2e-30 106.0 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Spc7 PF08317.11 KXZ53188.1 - 0.0094 14.9 44.3 0.052 12.4 20.5 3.0 2 1 1 3 3 3 2 Spc7 kinetochore protein DUF3727 PF12527.8 KXZ53188.1 - 2.1 8.7 6.8 11 6.4 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3727) GAS PF13851.6 KXZ53188.1 - 4.3 6.6 48.9 0.12 11.8 19.4 4.1 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KXZ53188.1 - 7.5 6.6 47.7 0.22 11.6 1.3 5.1 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.22 KXZ53188.1 - 8.5 6.7 36.9 5.1 7.4 5.3 4.2 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain PIG-S PF10510.9 KXZ53189.1 - 6.5e-61 206.7 0.0 3.3e-60 204.4 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Alanine_zipper PF11839.8 KXZ53189.1 - 1.9 8.9 13.8 5.4 7.5 4.6 2.7 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein NPL PF17800.1 KXZ53190.1 - 3.7e-10 40.3 0.0 3.7e-10 40.3 0.0 2.8 2 1 0 2 2 2 1 Nucleoplasmin-like domain OST-HTH PF12872.7 KXZ53190.1 - 0.071 12.9 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 OST-HTH/LOTUS domain Utp14 PF04615.13 KXZ53190.1 - 0.14 10.7 32.0 0.18 10.4 32.0 1.0 1 0 0 1 1 1 0 Utp14 protein zf-MYND PF01753.18 KXZ53191.1 - 2.5e-08 33.9 11.7 4.8e-08 32.9 11.7 1.5 1 0 0 1 1 1 1 MYND finger PhyH PF05721.13 KXZ53193.1 - 8.8e-08 32.7 0.1 5.4e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) WSC PF01822.19 KXZ53194.1 - 0.55 10.4 5.3 0.13 12.5 0.8 2.2 2 0 0 2 2 2 0 WSC domain Ank_2 PF12796.7 KXZ53195.1 - 5.3e-20 71.8 21.3 1.3e-05 25.7 1.1 4.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53195.1 - 7.1e-09 36.0 16.7 0.0056 17.2 0.3 6.3 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53195.1 - 1.2e-07 31.4 16.9 0.046 14.3 0.0 7.9 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KXZ53195.1 - 9.5e-05 22.6 18.0 0.051 13.9 0.2 5.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ketoacyl-synt_2 PF13723.6 KXZ53195.1 - 0.017 14.8 0.1 0.017 14.8 0.1 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ank PF00023.30 KXZ53195.1 - 0.043 14.3 29.0 0.37 11.3 0.1 7.2 5 1 1 6 6 6 0 Ankyrin repeat EF-hand_1 PF00036.32 KXZ53196.1 - 0.0014 18.0 0.1 0.0029 17.0 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ53196.1 - 0.0044 17.4 0.0 0.0056 17.1 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ53196.1 - 0.014 15.3 0.5 0.034 14.1 0.3 1.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 KXZ53196.1 - 0.022 14.3 0.2 0.036 13.6 0.2 1.3 1 0 0 1 1 1 0 EF hand SNARE PF05739.19 KXZ53196.1 - 0.094 12.7 0.3 0.22 11.5 0.3 1.7 1 0 0 1 1 1 0 SNARE domain VOMI PF03762.17 KXZ53197.1 - 4.5e-20 72.5 0.1 5.7e-17 62.4 0.0 2.3 1 1 1 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) DUF812 PF05667.11 KXZ53198.1 - 0.0021 17.1 11.8 0.0024 16.8 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DASH_Spc34 PF08657.10 KXZ53198.1 - 0.0029 17.4 7.1 0.0046 16.8 7.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Spc34 Fzo_mitofusin PF04799.13 KXZ53198.1 - 0.0051 16.4 12.4 0.011 15.3 12.4 1.5 1 0 0 1 1 1 1 fzo-like conserved region DUF3552 PF12072.8 KXZ53198.1 - 0.017 14.6 23.4 0.031 13.7 23.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 KXZ53198.1 - 0.018 14.7 7.5 0.023 14.3 7.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BshC PF10079.9 KXZ53198.1 - 0.055 12.2 13.0 0.078 11.7 13.0 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Atg14 PF10186.9 KXZ53198.1 - 0.1 11.6 21.1 0.16 11.0 21.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MCU PF04678.13 KXZ53198.1 - 0.12 12.5 7.0 0.22 11.6 7.0 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1974 PF09317.11 KXZ53198.1 - 0.17 11.4 6.1 0.26 10.8 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Jnk-SapK_ap_N PF09744.9 KXZ53198.1 - 0.19 11.9 24.2 0.35 11.1 24.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 KXZ53198.1 - 0.32 11.0 15.6 0.48 10.5 14.4 1.8 2 0 0 2 2 2 0 Laminin Domain II KxDL PF10241.9 KXZ53198.1 - 0.84 9.9 20.5 2.3 8.6 20.5 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein HemX PF04375.14 KXZ53198.1 - 0.9 8.8 19.2 1.7 7.9 19.2 1.5 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase BLOC1_2 PF10046.9 KXZ53198.1 - 2.1 8.7 20.3 4.6 7.6 20.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KXZ53198.1 - 2.5 8.6 19.1 4.8 7.7 19.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 HSP70 PF00012.20 KXZ53198.1 - 2.5 6.2 13.6 3.5 5.7 13.6 1.2 1 0 0 1 1 1 0 Hsp70 protein EIAV_Rev PF11129.8 KXZ53198.1 - 2.8 8.2 11.4 0.43 10.8 3.6 2.2 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus 5_nucleotid PF05761.14 KXZ53198.1 - 3 6.6 11.9 4.6 6.0 11.9 1.2 1 0 0 1 1 1 0 5' nucleotidase family DUF4407 PF14362.6 KXZ53198.1 - 3.3 7.0 10.4 4.7 6.5 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GPO PF05929.11 KXZ53198.1 - 7.2 6.1 16.0 3.4 7.2 11.7 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.12 KXZ53198.1 - 7.5 6.6 15.4 13 5.8 13.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3987 PF13148.6 KXZ53198.1 - 8.7 5.2 9.3 14 4.6 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TauD PF02668.16 KXZ53199.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family GRP PF07172.11 KXZ53200.1 - 0.00069 20.3 0.2 0.0019 18.8 0.2 1.7 1 0 0 1 1 1 1 Glycine rich protein family TPP_enzyme_N PF02776.18 KXZ53200.1 - 0.054 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain V_ATPase_I PF01496.19 KXZ53200.1 - 0.064 11.2 0.0 2.6 5.8 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FA_desaturase PF00487.24 KXZ53200.1 - 0.09 12.6 1.4 0.12 12.2 1.4 1.1 1 0 0 1 1 1 0 Fatty acid desaturase AD PF09793.9 KXZ53200.1 - 0.79 9.9 3.9 0.49 10.6 0.5 2.2 2 1 0 2 2 2 0 Anticodon-binding domain Myosin_tail_1 PF01576.19 KXZ53202.1 - 0.0045 14.9 19.4 0.0064 14.4 19.4 1.1 1 0 0 1 1 1 1 Myosin tail FlaC_arch PF05377.11 KXZ53202.1 - 0.014 15.8 4.0 7.2 7.1 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 KXZ53202.1 - 0.044 13.9 13.1 0.35 11.0 3.2 3.6 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF4795 PF16043.5 KXZ53202.1 - 0.27 10.8 6.9 0.47 10.0 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Filament PF00038.21 KXZ53202.1 - 0.33 10.5 20.1 0.1 12.2 8.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein TBCC_N PF16752.5 KXZ53202.1 - 1.2 9.5 7.7 0.29 11.6 3.4 1.9 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF4407 PF14362.6 KXZ53202.1 - 1.5 8.1 13.7 2.5 7.4 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KXZ53202.1 - 9.6 5.7 10.9 14 5.1 10.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Redoxin PF08534.10 KXZ53203.1 - 8e-36 123.0 0.0 1e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXZ53203.1 - 1.6e-14 53.9 0.0 1.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family TMEM234 PF10639.9 KXZ53204.1 - 0.018 15.1 0.9 0.027 14.5 0.9 1.3 1 0 0 1 1 1 0 Putative transmembrane family 234 Ins_beta PF03488.14 KXZ53204.1 - 0.11 12.6 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Patched PF02460.18 KXZ53205.1 - 3.4e-44 151.2 0.0 5.9e-29 100.8 0.0 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 KXZ53205.1 - 2.7e-30 105.2 1.4 2.7e-30 105.2 1.4 2.7 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation PsbP PF01789.16 KXZ53206.1 - 1.1e-33 116.6 0.0 1.6e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 PsbP PsbQ PF05757.11 KXZ53206.1 - 7.9e-05 22.5 0.4 0.00013 21.8 0.4 1.3 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) IMS PF00817.20 KXZ53208.1 - 7e-43 146.2 0.0 1.6e-42 145.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXZ53208.1 - 2e-19 70.4 0.0 4.5e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KXZ53208.1 - 1.9e-09 37.8 0.0 3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain UBM PF14377.6 KXZ53208.1 - 7.5e-09 34.8 10.3 0.0001 21.6 1.0 3.6 3 0 0 3 3 3 2 Ubiquitin binding region BRCT PF00533.26 KXZ53208.1 - 1.2e-06 28.8 0.0 2.6e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 KXZ53208.1 - 5.7e-06 26.4 0.1 1.5e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 IMS family HHH motif PTCB-BRCT PF12738.7 KXZ53208.1 - 0.00015 21.6 0.0 0.00042 20.2 0.0 1.8 1 1 0 1 1 1 1 twin BRCT domain Cdd1 PF11731.8 KXZ53208.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus Sdh5 PF03937.16 KXZ53209.1 - 1.6e-21 76.0 0.1 2.2e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase XPC-binding PF09280.11 KXZ53209.1 - 0.062 13.0 1.4 2.4 8.0 0.3 2.3 2 0 0 2 2 2 0 XPC-binding domain Formyl_trans_N PF00551.19 KXZ53210.1 - 8.7e-50 169.0 0.0 1e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Ribosomal_L14 PF00238.19 KXZ53211.1 - 4.6e-28 97.8 0.0 5e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Mpv17_PMP22 PF04117.12 KXZ53212.1 - 3.7e-21 75.1 1.6 3.7e-21 75.1 1.6 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Sensor_TM1 PF13755.6 KXZ53212.1 - 0.0067 16.1 0.8 0.054 13.2 0.4 2.1 2 0 0 2 2 2 1 Sensor N-terminal transmembrane domain Pacs-1 PF10254.9 KXZ53212.1 - 0.16 10.9 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein CBM_20 PF00686.19 KXZ53213.1 - 0.00041 20.2 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain GTSE1_N PF15259.6 KXZ53213.1 - 0.17 12.1 0.1 0.4 10.8 0.1 1.6 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Pkinase PF00069.25 KXZ53214.1 - 4.1e-64 216.5 0.0 5.8e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53214.1 - 1.1e-35 123.2 0.0 2.6e-35 122.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXZ53214.1 - 5.8e-05 22.2 0.0 8.6e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXZ53214.1 - 0.00037 19.9 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ53214.1 - 0.002 18.1 1.3 0.015 15.3 0.0 2.8 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ53214.1 - 0.0037 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ53214.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KXZ53215.1 - 3.5e-57 193.8 0.0 4.1e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53215.1 - 8e-19 67.9 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ53215.1 - 1.6e-06 28.3 1.4 0.00046 20.2 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ53215.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AbfS_sensor PF18225.1 KXZ53215.1 - 0.021 14.7 0.3 0.068 13.1 0.3 1.9 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain Pkinase_fungal PF17667.1 KXZ53215.1 - 0.031 13.1 0.0 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 KXZ53215.1 - 0.069 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KXZ53215.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_15 PF09445.10 KXZ53216.1 - 0.049 13.2 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PepSY_2 PF13670.6 KXZ53216.1 - 1.8 8.6 10.0 0.064 13.3 3.8 1.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain RCC1 PF00415.18 KXZ53218.1 - 2.1e-22 79.5 9.8 3.6e-10 40.3 0.1 4.6 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ53218.1 - 3.2e-05 23.6 9.5 0.11 12.3 0.1 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BRX PF08381.11 KXZ53218.1 - 0.0032 16.8 0.0 0.0075 15.6 0.0 1.6 1 0 0 1 1 1 1 Transcription factor regulating root and shoot growth via Pin3 CENP-B_dimeris PF09026.10 KXZ53218.1 - 0.23 11.9 3.3 0.57 10.6 3.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RCC1 PF00415.18 KXZ53219.1 - 1.1e-34 118.8 17.1 4.6e-12 46.4 0.5 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXZ53219.1 - 2.3e-16 59.1 12.1 4.8e-06 26.2 0.1 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Got1 PF04178.12 KXZ53220.1 - 1.7e-31 108.9 16.1 2.1e-31 108.6 16.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Mid2 PF04478.12 KXZ53220.1 - 0.0085 15.9 0.1 0.0085 15.9 0.1 1.9 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF1270 PF06900.11 KXZ53220.1 - 0.081 13.3 0.6 0.081 13.3 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1270) PGF-CTERM PF18204.1 KXZ53220.1 - 4.2 7.5 8.5 44 4.2 0.1 3.1 2 0 0 2 2 2 0 PGF-CTERM motif CAF1A PF12253.8 KXZ53221.1 - 2.2e-17 63.0 0.4 7e-17 61.4 0.4 1.9 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Gasdermin_C PF17708.1 KXZ53221.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Gasdermin PUB domain Rrn6 PF10214.9 KXZ53221.1 - 7.1 5.0 5.2 11 4.4 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Tubulin PF00091.25 KXZ53222.1 - 2.1e-36 126.0 0.0 2.4e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 KXZ53222.1 - 1.6e-05 25.2 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KXZ53223.1 - 1.2e-68 231.2 0.0 1.6e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXZ53223.1 - 3.6e-24 85.3 0.0 5.5e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXZ53223.1 - 7.9e-05 22.9 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KXZ53223.1 - 0.00093 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 KXZ53223.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain DUF1997 PF09366.10 KXZ53224.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) RR_TM4-6 PF06459.12 KXZ53225.1 - 0.15 11.8 1.5 0.27 11.0 1.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mt_ATP-synt_B PF05405.14 KXZ53225.1 - 0.3 10.7 2.5 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4366 PF14283.6 KXZ53225.1 - 0.42 10.6 2.4 12 5.9 2.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) MIP PF00230.20 KXZ53226.1 - 4.5e-39 134.5 21.3 2.8e-38 131.9 21.3 2.0 1 1 0 1 1 1 1 Major intrinsic protein U-box PF04564.15 KXZ53227.1 - 6.4e-09 35.9 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXZ53227.1 - 2.4e-05 24.1 0.0 0.00029 20.6 0.0 2.4 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KXZ53227.1 - 0.00036 20.6 0.0 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein RRM_1 PF00076.22 KXZ53229.1 - 3.6e-08 33.1 0.1 0.00084 19.1 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 KXZ53229.1 - 0.092 12.8 0.0 0.47 10.4 0.1 2.0 2 0 0 2 2 2 0 Smg-4/UPF3 family THRAP3_BCLAF1 PF15440.6 KXZ53229.1 - 0.39 9.7 5.2 0.49 9.4 5.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family RBM39linker PF15519.6 KXZ53229.1 - 2.4 9.3 9.3 1.9 9.6 0.8 2.7 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein RSRP PF17069.5 KXZ53229.1 - 3.4 7.2 14.3 5.9 6.4 14.3 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 eIF-4B PF06273.11 KXZ53230.1 - 0.00041 19.5 10.1 0.00041 19.5 10.1 2.3 1 1 0 2 2 2 1 Plant specific eukaryotic initiation factor 4B MBOAT_2 PF13813.6 KXZ53231.1 - 0.0015 18.7 1.0 0.004 17.4 0.6 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family TPR_2 PF07719.17 KXZ53232.1 - 3e-45 148.7 11.7 8e-07 28.7 0.0 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ53232.1 - 1.6e-38 128.9 16.0 5.4e-07 29.2 0.0 9.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ53232.1 - 3.4e-32 107.9 8.6 2.3e-05 24.3 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ53232.1 - 5.3e-28 97.1 14.3 1.8e-07 31.3 0.0 7.9 5 3 2 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ53232.1 - 5.2e-26 90.0 11.4 1.7e-05 24.4 0.0 9.2 4 2 5 9 9 9 6 TPR repeat TPR_16 PF13432.6 KXZ53232.1 - 4.2e-24 84.9 0.7 0.00054 20.6 0.6 7.4 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ53232.1 - 1.4e-21 75.4 2.7 0.0064 17.2 0.0 9.5 4 2 6 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ53232.1 - 1.5e-20 72.0 11.1 0.0039 17.5 0.0 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ53232.1 - 2e-19 69.8 2.3 0.00014 22.3 0.0 6.5 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ53232.1 - 2.5e-17 62.3 9.3 0.02 15.5 0.0 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ53232.1 - 2.6e-15 56.4 13.5 0.0027 17.9 0.1 6.2 3 2 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXZ53232.1 - 2.8e-15 55.1 0.4 0.39 10.9 0.0 8.1 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ53232.1 - 2.9e-15 56.2 0.4 0.018 15.2 0.0 6.0 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ53232.1 - 6e-09 35.5 16.3 0.11 12.4 0.4 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat NARP1 PF12569.8 KXZ53232.1 - 2e-06 27.0 1.4 0.043 12.7 0.0 3.4 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 KXZ53232.1 - 9e-06 25.1 0.5 0.14 11.4 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXZ53232.1 - 2e-05 24.2 3.0 0.0049 16.3 0.2 3.2 2 1 0 3 3 3 1 MalT-like TPR region Wzy_C_2 PF11846.8 KXZ53232.1 - 2.1e-05 24.6 1.8 0.0083 16.1 0.7 3.2 3 1 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal PknG_TPR PF16918.5 KXZ53232.1 - 0.00013 20.9 0.1 0.094 11.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat Coatomer_E PF04733.14 KXZ53232.1 - 0.00016 21.2 0.5 0.31 10.4 0.2 3.6 1 1 2 4 4 4 1 Coatomer epsilon subunit TPR_4 PF07721.14 KXZ53232.1 - 0.00075 19.9 0.0 20 6.2 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ53232.1 - 0.0019 18.5 0.8 7 7.1 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3808 PF10300.9 KXZ53232.1 - 0.0033 16.2 2.4 0.29 9.8 0.1 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF3808) BTAD PF03704.17 KXZ53232.1 - 0.008 16.6 0.1 2.4 8.6 0.0 3.4 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_3 PF07720.12 KXZ53232.1 - 0.0091 16.0 23.2 3.6 7.7 0.8 7.1 7 1 1 8 8 7 1 Tetratricopeptide repeat SNAP PF14938.6 KXZ53232.1 - 0.022 14.2 1.2 1.8 7.9 0.1 3.3 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 KXZ53232.1 - 0.031 13.3 0.0 8.4 5.3 0.0 2.6 1 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Paf67 PF10255.9 KXZ53232.1 - 0.52 9.2 4.1 7.7 5.4 0.1 3.4 3 1 1 4 4 4 0 RNA polymerase I-associated factor PAF67 Fis1_TPR_C PF14853.6 KXZ53232.1 - 1.5 8.9 12.1 78 3.4 0.0 5.8 6 1 1 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 KXZ53232.1 - 1.9 8.6 11.3 11 6.2 0.7 4.8 3 3 0 4 4 4 0 Anaphase-promoting complex subunit 5 PH PF00169.29 KXZ53233.1 - 5.7e-14 52.5 0.0 8.4e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 PH domain WW PF00397.26 KXZ53233.1 - 1e-09 38.3 4.6 1.9e-09 37.4 4.6 1.5 1 0 0 1 1 1 1 WW domain PH_11 PF15413.6 KXZ53233.1 - 0.00038 20.9 0.8 0.00092 19.6 0.8 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Chloroa_b-bind PF00504.21 KXZ53234.1 - 8.3e-51 172.7 0.1 1e-50 172.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 KXZ53235.1 - 8.3e-51 172.7 0.1 1e-50 172.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TMEM107 PF14995.6 KXZ53237.1 - 2.1e-25 89.6 3.3 2.5e-25 89.3 3.3 1.1 1 0 0 1 1 1 1 Transmembrane protein FHA PF00498.26 KXZ53238.1 - 1.7e-15 57.1 0.0 2.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXZ53238.1 - 1.1e-07 32.0 0.0 1.4e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Trypsin_2 PF13365.6 KXZ53239.1 - 3.3e-10 41.1 9.0 5.6e-08 33.8 9.0 3.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KXZ53239.1 - 0.019 14.8 0.1 0.68 9.7 0.1 2.4 2 0 0 2 2 2 0 Trypsin DUF4407 PF14362.6 KXZ53240.1 - 9.4 5.5 20.0 13 5.0 20.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HECT PF00632.25 KXZ53241.1 - 4.5e-25 88.8 0.0 2.4e-18 66.7 0.0 2.7 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) Peptidase_M13 PF01431.21 KXZ53241.1 - 0.044 13.4 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M13 Guanylate_cyc PF00211.20 KXZ53242.1 - 4.8e-42 143.6 0.0 7.7e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain BP28CT PF08146.12 KXZ53244.1 - 1.7e-35 122.2 0.0 4.4e-35 120.9 0.0 1.8 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KXZ53244.1 - 6.7e-17 61.9 0.2 4.3e-16 59.3 0.2 2.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 Tti2 PF10521.9 KXZ53244.1 - 0.023 14.2 0.9 7.7 6.0 0.0 4.0 4 0 0 4 4 4 0 Tti2 family Vac14_Fab1_bd PF12755.7 KXZ53244.1 - 0.048 14.3 0.0 13 6.5 0.0 3.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KXZ53244.1 - 0.33 11.1 6.1 32 4.7 0.0 5.0 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Smr PF01713.21 KXZ53245.1 - 6.9e-14 52.0 0.5 1.2e-13 51.2 0.5 1.4 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KXZ53245.1 - 8.2e-12 45.3 12.5 1.5e-11 44.5 12.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) TPR_17 PF13431.6 KXZ53245.1 - 0.09 13.2 1.2 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat OAM_dimer PF16554.5 KXZ53245.1 - 0.14 12.6 0.5 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Mito_carr PF00153.27 KXZ53246.1 - 3.7e-44 148.6 0.5 3.9e-20 71.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXZ53246.1 - 0.0079 15.4 0.1 0.65 9.1 0.0 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease FAM27 PF15832.5 KXZ53246.1 - 2.7 8.6 5.6 0.61 10.7 1.9 1.9 2 0 0 2 2 2 0 FAM27 D and E protein family TTL PF03133.15 KXZ53247.1 - 7.9e-35 120.4 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ53247.1 - 9.8e-06 25.0 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ53247.1 - 0.039 13.2 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF3138 PF11336.8 KXZ53247.1 - 4.3 5.9 9.8 7.7 5.0 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Leu_zip PF15294.6 KXZ53248.1 - 0.02 14.4 17.9 0.028 13.9 17.9 1.2 1 0 0 1 1 1 0 Leucine zipper YabA PF06156.13 KXZ53248.1 - 0.22 12.2 15.9 0.85 10.3 2.8 2.7 1 1 1 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 KXZ53248.1 - 0.27 11.7 11.2 0.063 13.7 3.3 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KXZ53248.1 - 0.3 11.1 9.5 0.2 11.7 7.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Gp-FAR-1 PF05823.12 KXZ53248.1 - 0.35 11.2 9.8 0.65 10.3 9.7 1.5 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MAD PF05557.13 KXZ53248.1 - 0.51 8.6 23.5 0.71 8.2 23.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Ribosomal_S20p PF01649.18 KXZ53248.1 - 0.67 10.6 14.8 18 6.1 14.0 2.6 1 1 0 1 1 1 0 Ribosomal protein S20 Cauli_AT PF03233.13 KXZ53248.1 - 0.77 9.7 4.7 1.1 9.1 1.8 2.0 1 1 1 2 2 2 0 Aphid transmission protein DNA_topoisoIV PF00521.20 KXZ53248.1 - 0.84 8.4 10.2 1 8.2 10.2 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Rootletin PF15035.6 KXZ53248.1 - 1.4 9.0 28.3 0.85 9.6 12.9 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Phage_GP20 PF06810.11 KXZ53248.1 - 1.5 8.6 18.0 1.5 8.7 5.9 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF16 PF01519.16 KXZ53248.1 - 1.6 9.3 14.7 1.3 9.6 4.5 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF16 IFT57 PF10498.9 KXZ53248.1 - 2 7.3 15.4 15 4.4 15.0 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Occludin_ELL PF07303.13 KXZ53248.1 - 2.3 9.0 11.6 0.77 10.5 0.9 2.3 1 1 1 2 2 2 0 Occludin homology domain Csm2_III-A PF03750.13 KXZ53248.1 - 3 8.7 12.1 18 6.2 9.3 2.6 1 1 1 2 2 2 0 Csm2 Type III-A Latarcin PF10279.9 KXZ53248.1 - 3.1 8.2 12.0 0.59 10.6 3.9 2.4 1 1 1 2 2 2 0 Latarcin precursor Rx_N PF18052.1 KXZ53248.1 - 3.2 8.1 15.8 1.2 9.5 6.5 2.3 1 1 1 2 2 2 0 Rx N-terminal domain DUF1925 PF09094.11 KXZ53248.1 - 3.2 8.1 6.5 0.83 10.0 1.7 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1925) She9_MDM33 PF05546.11 KXZ53248.1 - 3.3 7.5 15.5 4.3 7.1 13.8 1.8 1 1 1 2 2 2 0 She9 / Mdm33 family V_ATPase_I PF01496.19 KXZ53248.1 - 3.3 5.5 11.8 4.2 5.2 11.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAP1_N PF04849.13 KXZ53248.1 - 4.3 6.5 25.1 9 5.4 25.1 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Spc7 PF08317.11 KXZ53248.1 - 4.7 6.0 26.8 1.6 7.5 22.6 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KXZ53248.1 - 5.3 7.7 12.0 3.5 8.2 6.9 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RICH PF05062.12 KXZ53248.1 - 6.2 7.3 13.0 29 5.1 0.2 3.4 1 1 2 3 3 3 0 RICH domain AAA_13 PF13166.6 KXZ53248.1 - 6.6 5.2 15.2 11 4.5 15.2 1.3 1 0 0 1 1 1 0 AAA domain PEARLI-4 PF05278.12 KXZ53248.1 - 9.5 5.7 16.9 0.96 9.0 6.2 2.2 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DGF-1_C PF11040.8 KXZ53249.1 - 0.84 9.7 12.4 0.55 10.3 2.3 3.3 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Glyoxalase PF00903.25 KXZ53250.1 - 0.00024 21.3 0.1 0.024 14.8 0.0 2.3 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXZ53250.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily VPS9 PF02204.18 KXZ53251.1 - 6.1e-22 77.8 0.1 1.5e-21 76.6 0.0 1.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXZ53251.1 - 2.1e-08 34.3 0.0 8.8e-08 32.4 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF5601) DUF826 PF05696.11 KXZ53251.1 - 0.067 13.3 0.6 0.3 11.2 0.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Mpv17_PMP22 PF04117.12 KXZ53252.1 - 4.1e-17 62.2 0.0 6.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family N-glycanase_C PF09113.10 KXZ53253.1 - 3.2e-30 104.7 0.0 5.2e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Peptide-N-glycosidase F, C terminal N-glycanase_N PF09112.10 KXZ53253.1 - 5.2e-11 42.6 0.0 1.4e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 Peptide-N-glycosidase F, N terminal PA PF02225.22 KXZ53253.1 - 0.00017 21.5 4.2 0.0014 18.6 0.7 3.2 2 1 0 2 2 2 1 PA domain Nop14 PF04147.12 KXZ53253.1 - 0.007 14.6 2.8 0.0097 14.2 2.8 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KXZ53253.1 - 0.22 9.8 7.1 0.3 9.3 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_11 PF08241.12 KXZ53254.1 - 7e-11 42.6 0.1 1.8e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ53254.1 - 1e-06 29.4 0.0 1.8e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ53254.1 - 1.4e-06 28.9 0.0 3.1e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ53254.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ53254.1 - 0.001 18.9 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ53254.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KXZ53254.1 - 0.0025 17.7 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase N6_N4_Mtase PF01555.18 KXZ53254.1 - 0.0043 16.8 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 DNA methylase MetW PF07021.12 KXZ53254.1 - 0.03 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Bin3 PF06859.12 KXZ53254.1 - 0.035 14.8 0.0 0.063 13.9 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_29 PF03141.16 KXZ53254.1 - 0.065 11.8 0.0 0.089 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TsaE PF02367.17 KXZ53256.1 - 0.061 13.3 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NYN PF01936.18 KXZ53257.1 - 2.4e-05 24.8 0.0 9.5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 NYN domain FSA_C PF10479.9 KXZ53257.1 - 0.28 9.3 0.4 0.41 8.7 0.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Jak1_Phl PF17887.1 KXZ53257.1 - 4.9 7.1 5.0 8.9 6.3 5.0 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain LRR_4 PF12799.7 KXZ53258.1 - 2.1e-19 69.2 8.0 0.15 12.5 0.1 10.4 9 2 3 13 13 13 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ53258.1 - 1.3e-12 46.7 39.6 0.038 14.0 0.0 14.6 17 0 0 17 17 17 6 Leucine Rich repeat LRR_8 PF13855.6 KXZ53258.1 - 2.6e-12 46.3 18.7 0.0099 15.6 0.0 8.5 7 1 2 9 9 9 5 Leucine rich repeat LRR_1 PF00560.33 KXZ53258.1 - 1.4 9.8 28.1 23 6.0 0.3 11.0 13 2 1 14 14 14 0 Leucine Rich Repeat Amidinotransf PF02274.17 KXZ53259.1 - 2.1e-06 27.1 0.0 1e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Amidinotransferase Pkinase_Tyr PF07714.17 KXZ53260.1 - 2.1e-37 128.8 0.0 4.4e-32 111.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ53260.1 - 1.1e-33 116.7 0.0 3.5e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ53260.1 - 0.00062 19.2 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ53260.1 - 0.0068 16.4 1.5 0.019 14.9 0.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ53260.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KXZ53260.1 - 0.074 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Guanylate_cyc PF00211.20 KXZ53261.1 - 9.3e-28 97.1 1.5 1.3e-21 77.0 0.1 2.4 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SepSecS PF05889.13 KXZ53262.1 - 3e-119 398.2 0.0 1.2e-108 363.4 0.0 2.0 2 0 0 2 2 2 2 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KXZ53262.1 - 1.5e-06 27.8 1.1 2e-06 27.3 1.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXZ53262.1 - 0.00025 20.4 0.1 0.00071 18.9 0.1 1.6 1 1 1 2 2 2 1 Aminotransferase class I and II Guanylate_cyc PF00211.20 KXZ53263.1 - 2.6e-32 111.9 0.1 3.8e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MTS PF05175.14 KXZ53263.1 - 0.14 11.7 0.1 0.6 9.6 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Guanylate_cyc PF00211.20 KXZ53264.1 - 1.3e-32 112.9 0.1 2.1e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ53265.1 - 1.3e-45 155.2 0.1 2.1e-44 151.3 0.2 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ53266.1 - 5.4e-34 117.4 0.1 8.5e-34 116.8 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ABC2_membrane PF01061.24 KXZ53267.1 - 2.1e-40 138.4 5.2 2.9e-40 137.9 5.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ53267.1 - 1.1e-18 68.1 0.0 1.8e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXZ53267.1 - 6.2e-05 22.3 3.8 9.5e-05 21.7 3.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 KXZ53267.1 - 6.6e-05 23.4 0.2 0.00026 21.4 0.2 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KXZ53267.1 - 0.02 14.5 0.3 0.02 14.5 0.3 1.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KXZ53267.1 - 0.023 14.5 0.3 0.52 10.1 0.5 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 KXZ53267.1 - 0.026 13.8 1.3 0.057 12.7 1.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KXZ53267.1 - 0.097 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXZ53267.1 - 0.14 12.0 0.3 0.39 10.5 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain LRR_4 PF12799.7 KXZ53268.1 - 0.1 13.1 7.2 8.6 6.9 0.0 6.0 8 0 0 8 8 8 0 Leucine Rich repeats (2 copies) Mpv17_PMP22 PF04117.12 KXZ53269.1 - 7.9e-17 61.2 0.0 1.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TPR_14 PF13428.6 KXZ53270.1 - 0.0019 18.9 0.3 0.17 12.8 0.1 7.9 6 2 4 10 10 10 2 Tetratricopeptide repeat Nitrate_red_del PF02613.15 KXZ53270.1 - 0.0065 16.5 0.4 0.068 13.2 0.0 2.5 2 0 0 2 2 2 1 Nitrate reductase delta subunit SRP1_TIP1 PF00660.17 KXZ53270.1 - 0.089 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Seripauperin and TIP1 family RRM_1 PF00076.22 KXZ53271.1 - 2e-11 43.5 1.5 2.7e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 KXZ53271.1 - 8.9e-07 28.2 0.7 2.4e-06 26.8 0.7 1.8 1 0 0 1 1 1 1 Lsm interaction motif Suf PF05843.14 KXZ53271.1 - 0.0044 17.1 0.2 0.0063 16.5 0.2 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Menin PF05053.13 KXZ53271.1 - 0.1 11.0 12.3 0.12 10.7 12.3 1.1 1 0 0 1 1 1 0 Menin SRP-alpha_N PF04086.13 KXZ53271.1 - 1.9 8.3 14.3 3.1 7.6 14.3 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal UQ_con PF00179.26 KXZ53272.1 - 1.3e-53 180.4 0.0 1.5e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXZ53272.1 - 0.18 11.5 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B zf-C3HC4 PF00097.25 KXZ53273.1 - 1.4e-07 31.2 3.1 2.4e-07 30.5 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ53273.1 - 1.7e-07 30.9 3.0 3.1e-07 30.1 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ53273.1 - 1.1e-05 25.3 3.9 2.1e-05 24.4 3.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXZ53273.1 - 1.8e-05 24.5 4.3 2.8e-05 23.9 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ53273.1 - 0.00013 21.8 4.9 0.0002 21.3 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXZ53273.1 - 0.00015 21.3 3.7 0.00024 20.7 3.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KXZ53273.1 - 0.0005 20.3 5.4 0.00082 19.7 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXZ53273.1 - 0.00053 20.1 4.4 0.00096 19.3 4.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KXZ53273.1 - 0.0014 18.4 3.6 0.0021 17.9 3.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KXZ53273.1 - 0.0021 18.2 4.4 0.0033 17.5 4.4 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 KXZ53273.1 - 0.0052 16.6 2.7 0.009 15.9 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KXZ53273.1 - 0.014 15.2 1.4 0.022 14.6 1.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KXZ53273.1 - 0.033 14.5 0.8 0.066 13.5 0.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXZ53273.1 - 0.088 12.7 4.7 0.13 12.1 4.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXZ53273.1 - 0.099 12.4 1.4 0.18 11.6 1.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 KXZ53273.1 - 0.1 12.9 4.7 2.7 8.3 2.5 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 KXZ53273.1 - 0.21 11.7 2.0 4.7 7.4 2.0 2.2 1 1 0 1 1 1 0 FYVE zinc finger LRR_4 PF12799.7 KXZ53274.1 - 0.0056 17.1 18.5 1.4 9.4 0.3 7.0 6 2 1 7 7 7 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXZ53274.1 - 0.062 13.2 0.1 0.24 11.3 0.1 2.1 1 0 0 1 1 1 0 F-box-like HSP70 PF00012.20 KXZ53275.1 - 9e-16 57.2 0.0 1.2e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Ammonium_transp PF00909.21 KXZ53276.1 - 3e-115 385.1 27.5 3.7e-115 384.8 27.5 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family YuiB PF14068.6 KXZ53276.1 - 0.021 15.4 0.3 0.26 11.9 0.0 2.7 2 0 0 2 2 2 0 Putative membrane protein Ribosomal_L37 PF08561.10 KXZ53277.1 - 2.4e-14 53.9 1.1 9.4e-09 35.8 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 DXP_reductoisom PF02670.16 KXZ53278.1 - 6.5e-47 159.4 0.1 1.4e-46 158.4 0.1 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 KXZ53278.1 - 1.7e-39 133.9 0.0 3.7e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXPR_C PF13288.6 KXZ53278.1 - 5.3e-37 126.6 0.0 9.5e-37 125.8 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain Semialdhyde_dh PF01118.24 KXZ53278.1 - 0.12 12.9 0.0 0.46 10.9 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Kinesin PF00225.23 KXZ53279.1 - 4.2e-74 249.5 0.0 2.3e-73 247.0 0.0 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ53279.1 - 1.5e-16 60.7 0.0 7.3e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Microtubule binding DUF3584 PF12128.8 KXZ53279.1 - 0.11 10.0 30.6 0.22 9.0 30.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) 3-PAP PF12578.8 KXZ53279.1 - 1.1 9.0 4.3 22 4.8 0.1 3.3 3 0 0 3 3 3 0 Myotubularin-associated protein Ax_dynein_light PF10211.9 KXZ53279.1 - 2.5 8.0 25.2 1.5 8.7 2.5 4.4 3 1 1 4 4 4 0 Axonemal dynein light chain SAM_KSR1 PF13543.6 KXZ53279.1 - 8.1 6.6 9.5 42 4.3 0.1 2.8 2 1 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 PetM PF08041.11 KXZ53280.1 - 3.2e-06 26.6 1.3 6e-06 25.7 1.3 1.5 1 0 0 1 1 1 1 PetM family of cytochrome b6f complex subunit 7 Rhomboid PF01694.22 KXZ53281.1 - 7.8e-13 48.7 8.6 7.8e-13 48.7 8.6 1.8 2 0 0 2 2 2 1 Rhomboid family GvpK PF05121.12 KXZ53281.1 - 0.17 11.9 1.4 0.27 11.3 1.4 1.3 1 0 0 1 1 1 0 Gas vesicle protein K Taxilin PF09728.9 KXZ53282.1 - 4.1e-51 174.0 59.6 3.8e-48 164.3 58.2 2.9 1 1 1 2 2 2 2 Myosin-like coiled-coil protein DUF812 PF05667.11 KXZ53282.1 - 0.079 11.8 41.4 0.11 11.4 41.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 KXZ53282.1 - 0.73 9.9 28.1 0.19 11.8 0.8 5.4 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KXZ53282.1 - 1.1 9.8 20.3 6.8 7.2 1.6 5.1 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF5638 PF18688.1 KXZ53282.1 - 7.6 6.9 10.6 0.85 10.0 1.2 3.2 2 1 0 3 3 3 0 Family of unknown function (DUF5638) Mg_trans_NIPA PF05653.14 KXZ53283.1 - 4.5e-93 311.6 21.5 5.4e-93 311.3 21.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXZ53283.1 - 0.00068 19.8 5.4 0.00068 19.8 5.4 3.1 2 1 1 3 3 3 2 EamA-like transporter family Multi_Drug_Res PF00893.19 KXZ53283.1 - 2.1 9.1 11.1 0.51 11.0 3.9 3.2 2 1 2 4 4 4 0 Small Multidrug Resistance protein Robl_LC7 PF03259.17 KXZ53284.1 - 3.6e-12 45.9 0.0 4.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KXZ53284.1 - 0.068 13.1 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 RAB3GAP2_N PF14655.6 KXZ53285.1 - 1.4e-15 57.5 0.0 5.1e-15 55.6 0.0 1.7 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DOMON PF03351.17 KXZ53286.1 - 1.3e-06 28.7 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXZ53286.1 - 6.9e-06 26.2 6.8 1.2e-05 25.4 6.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KXZ53286.1 - 0.21 11.4 1.7 0.5 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Fea1 PF07692.11 KXZ53287.1 - 2.8e-79 266.8 15.6 3.3e-79 266.6 15.6 1.0 1 0 0 1 1 1 1 Low iron-inducible periplasmic protein Fea1 PF07692.11 KXZ53288.1 - 1.9e-90 303.5 15.4 5.7e-79 265.8 10.8 2.0 1 1 1 2 2 2 2 Low iron-inducible periplasmic protein Endonuc_Holl PF10107.9 KXZ53289.1 - 0.77 9.6 5.2 0.25 11.2 1.5 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase FliJ PF02050.16 KXZ53290.1 - 0.017 15.3 12.2 0.017 15.3 12.2 7.1 3 1 5 8 8 8 0 Flagellar FliJ protein HSP70 PF00012.20 KXZ53291.1 - 7e-13 47.6 0.5 0.00015 20.1 0.0 3.2 3 0 0 3 3 3 3 Hsp70 protein Hemerythrin PF01814.23 KXZ53292.1 - 0.0085 16.7 0.9 0.0085 16.7 0.9 1.8 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Geminin PF07412.12 KXZ53292.1 - 0.048 13.4 2.3 0.078 12.7 2.3 1.2 1 0 0 1 1 1 0 Geminin Cep57_CLD_2 PF14197.6 KXZ53292.1 - 0.099 12.7 7.3 0.19 11.9 7.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF5309 PF17236.2 KXZ53292.1 - 0.18 11.1 0.1 0.26 10.6 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5309) TMF_DNA_bd PF12329.8 KXZ53292.1 - 0.24 11.4 3.9 0.27 11.2 1.8 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.6 KXZ53292.1 - 1.6 8.8 5.0 61 3.7 6.2 2.3 2 0 0 2 2 2 0 FlxA-like protein DivIC PF04977.15 KXZ53292.1 - 2.7 7.8 5.3 1.1 9.0 2.4 1.8 1 1 0 1 1 1 0 Septum formation initiator HSP70 PF00012.20 KXZ53293.1 - 1.3e-07 30.2 0.2 0.0088 14.3 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein HIP1_clath_bdg PF16515.5 KXZ53294.1 - 0.029 15.0 1.3 0.053 14.1 1.3 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Actin PF00022.19 KXZ53296.1 - 2.1e-65 220.9 0.0 1.9e-64 217.8 0.0 1.9 1 1 0 1 1 1 1 Actin FtsA PF14450.6 KXZ53296.1 - 0.018 15.5 0.0 0.19 12.2 0.0 2.4 3 0 0 3 3 3 0 Cell division protein FtsA ubiquitin PF00240.23 KXZ53299.1 - 2e-09 37.1 0.0 4.6e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KXZ53299.1 - 0.0051 17.3 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KXZ53299.1 - 0.099 12.7 0.0 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain Ank_4 PF13637.6 KXZ53302.1 - 2.6e-24 85.3 2.4 2.5e-08 34.3 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ53302.1 - 1.2e-20 73.9 0.1 0.00011 22.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ53302.1 - 4.8e-14 51.1 3.1 0.00035 20.8 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KXZ53302.1 - 2.5e-11 43.5 2.0 0.002 18.5 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KXZ53302.1 - 8.3e-11 41.9 5.0 0.00048 20.4 0.1 5.5 4 2 2 6 6 6 4 Ankyrin repeats (many copies) PAM2 PF07145.15 KXZ53302.1 - 0.0022 17.6 0.1 0.0054 16.3 0.1 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region PUF PF00806.19 KXZ53303.1 - 1.6e-54 178.6 4.2 4.3e-09 35.6 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat NOA36 PF06524.12 KXZ53304.1 - 0.29 10.4 0.8 0.38 10.0 0.8 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KXZ53304.1 - 3.4 8.1 6.6 5.2 7.5 6.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EF-hand_1 PF00036.32 KXZ53305.1 - 0.00027 20.3 0.5 0.00047 19.5 0.5 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ53305.1 - 0.0036 17.1 0.2 0.0073 16.2 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXZ53305.1 - 0.007 16.2 0.3 0.012 15.4 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KXZ53305.1 - 0.18 12.3 0.3 0.29 11.6 0.3 1.3 1 0 0 1 1 1 0 EF-hand domain pair Dcc1 PF09724.9 KXZ53306.1 - 1.2e-89 300.9 0.0 1.4e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HATPase_c PF02518.26 KXZ53307.1 - 0.053 14.0 0.2 0.065 13.7 0.2 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sporozoite_P67 PF05642.11 KXZ53307.1 - 0.77 7.8 3.5 0.82 7.7 3.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BCDHK_Adom3 PF10436.9 KXZ53308.1 - 1.1e-42 145.7 0.1 1.3e-42 145.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase SQHop_cyclase_N PF13249.6 KXZ53309.1 - 0.015 14.4 2.2 0.024 13.8 2.2 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain HHH_6 PF14579.6 KXZ53310.1 - 0.013 15.8 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif LRR_4 PF12799.7 KXZ53310.1 - 0.11 13.0 0.1 37 4.9 0.0 2.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) OHA PF14418.6 KXZ53312.1 - 0.26 11.1 0.2 0.59 10.0 0.2 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain Transferase PF02458.15 KXZ53313.1 - 1.9e-21 76.3 0.0 1.9e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 Transferase family Hydrolase_like PF13242.6 KXZ53314.1 - 8.9e-18 64.1 0.0 2.4e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like ENTH PF01417.20 KXZ53314.1 - 5.1e-10 39.5 0.0 3.6e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Hydrolase PF00702.26 KXZ53314.1 - 1e-07 32.5 0.2 1.1e-05 25.9 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXZ53314.1 - 1e-05 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXZ53314.1 - 2.5e-05 24.3 0.0 6.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ald_Xan_dh_C2 PF02738.18 KXZ53315.1 - 2.1e-199 663.6 0.0 2.9e-199 663.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXZ53315.1 - 8.9e-49 165.5 0.1 1.8e-48 164.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KXZ53315.1 - 1.7e-30 105.6 1.0 3.4e-30 104.6 1.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KXZ53315.1 - 4.3e-30 103.9 0.6 1.1e-29 102.6 0.6 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KXZ53315.1 - 5e-30 103.3 0.0 1.4e-29 102.0 0.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain TPMT PF05724.11 KXZ53316.1 - 3.5e-08 33.4 0.0 5.8e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KXZ53316.1 - 1.1e-05 26.0 0.0 1.9e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ53316.1 - 0.0015 19.1 0.0 0.0024 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ53316.1 - 0.0071 17.1 0.0 0.011 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain zf-MYND PF01753.18 KXZ53317.1 - 8.4e-06 25.8 7.6 8.4e-06 25.8 7.6 1.9 2 0 0 2 2 2 1 MYND finger PBP1_TM PF14812.6 KXZ53317.1 - 1.5 9.2 3.4 3.5 8.1 3.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Elf1 PF05129.13 KXZ53318.1 - 1.1e-22 79.9 0.7 1.9e-22 79.1 0.7 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like GUN4_N PF16416.5 KXZ53318.1 - 0.046 13.7 1.5 0.086 12.8 1.5 1.4 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal zf-C2H2_3 PF13878.6 KXZ53318.1 - 0.074 12.9 2.1 0.24 11.3 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Lar_restr_allev PF14354.6 KXZ53318.1 - 0.54 10.7 5.2 1.4 9.4 5.2 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar PHD PF00628.29 KXZ53318.1 - 5.8 6.9 6.4 13 5.8 5.4 2.1 1 1 1 2 2 2 0 PHD-finger Pro_isomerase PF00160.21 KXZ53320.1 - 1.3e-12 48.3 0.0 1.4e-12 48.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-MYND PF01753.18 KXZ53321.1 - 2.4e-10 40.3 6.8 4.1e-10 39.6 6.8 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ53321.1 - 0.44 10.9 4.8 0.91 9.9 4.8 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Pro_isomerase PF00160.21 KXZ53323.1 - 1.4e-47 161.9 0.0 1.6e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arm PF00514.23 KXZ53324.1 - 1.2e-07 31.6 7.1 6.9e-05 22.7 0.1 4.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat RRM_1 PF00076.22 KXZ53325.1 - 6.4e-33 112.4 0.1 9.1e-17 60.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXZ53325.1 - 5.3e-05 23.2 0.0 0.059 13.4 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif RRM_5 PF13893.6 KXZ53325.1 - 0.0019 17.8 0.0 0.0086 15.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ53325.1 - 0.035 13.9 0.0 8.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Aldo_ket_red PF00248.21 KXZ53326.1 - 1.5e-10 40.8 0.0 3.2e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 KXZ53327.1 - 1.3e-35 123.0 0.0 1.9e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53327.1 - 2.5e-26 92.5 0.0 8e-26 90.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ53327.1 - 0.00046 19.6 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Med12 PF09497.10 KXZ53328.1 - 8e-11 42.1 1.0 1.1e-10 41.6 0.1 1.8 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 LMWPc PF01451.21 KXZ53329.1 - 2.4e-13 50.7 0.0 5.4e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FMO-like PF00743.19 KXZ53330.1 - 6.3e-09 34.8 0.0 2.8e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Septum_form PF13845.6 KXZ53334.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Septum formation ADH_zinc_N PF00107.26 KXZ53335.1 - 2.1e-25 89.2 0.2 4.6e-25 88.1 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXZ53335.1 - 7e-25 87.0 1.6 2.1e-24 85.5 1.6 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXZ53335.1 - 0.00083 18.7 0.2 0.0015 17.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXZ53335.1 - 0.0022 19.0 0.0 0.0042 18.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXZ53335.1 - 0.006 15.9 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXZ53335.1 - 0.0099 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KXZ53335.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PEP-CTERM PF07589.11 KXZ53335.1 - 0.14 12.3 0.3 0.48 10.6 0.2 2.0 2 0 0 2 2 2 0 PEP-CTERM motif ADH_zinc_N PF00107.26 KXZ53336.1 - 2e-25 89.3 0.2 4.3e-25 88.2 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXZ53336.1 - 3.1e-23 81.8 5.6 1.2e-16 60.6 1.3 2.8 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXZ53336.1 - 0.00078 18.8 0.2 0.0015 17.9 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXZ53336.1 - 0.004 18.2 0.0 0.0077 17.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXZ53336.1 - 0.0059 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXZ53336.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KXZ53336.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PEP-CTERM PF07589.11 KXZ53336.1 - 0.15 12.2 0.3 0.46 10.6 0.2 1.9 2 0 0 2 2 2 0 PEP-CTERM motif zf-rbx1 PF12678.7 KXZ53337.1 - 4e-21 75.0 5.4 7.8e-21 74.1 5.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXZ53337.1 - 2.8e-14 52.9 7.2 4.4e-14 52.3 7.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXZ53337.1 - 5.3e-09 36.3 11.1 3.8e-08 33.5 10.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ53337.1 - 1.6e-08 34.2 7.8 4.2e-07 29.7 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ53337.1 - 1.8e-07 30.9 1.7 6e-07 29.2 1.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ53337.1 - 1e-06 28.6 2.0 1.5e-06 28.2 1.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXZ53337.1 - 8.7e-05 22.3 7.0 9.1e-05 22.2 2.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXZ53337.1 - 0.00018 21.4 5.9 0.00052 19.9 6.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXZ53337.1 - 0.00053 19.8 6.3 0.001 18.9 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXZ53337.1 - 0.0018 17.8 3.7 0.0018 17.8 3.7 2.1 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXZ53337.1 - 0.0042 16.8 1.8 0.0042 16.8 1.8 2.8 2 1 0 2 2 2 1 RING-like zinc finger zf-Nse PF11789.8 KXZ53337.1 - 0.016 15.0 0.8 0.035 13.9 0.8 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KXZ53337.1 - 0.049 13.8 4.0 0.049 13.8 4.0 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 KXZ53337.1 - 0.057 12.8 0.1 0.057 12.8 0.1 2.2 2 1 1 3 3 3 0 Rtf2 RING-finger DiS_P_DiS PF06750.13 KXZ53337.1 - 0.4 10.8 3.2 11 6.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-C3H2C3 PF17122.5 KXZ53337.1 - 0.97 9.5 6.3 0.46 10.6 2.5 2.2 2 1 0 2 2 2 0 Zinc-finger zinc_ribbon_16 PF17034.5 KXZ53337.1 - 1.1 9.5 6.9 0.22 11.7 2.3 1.9 2 1 0 2 2 2 0 Zinc-ribbon like family RINGv PF12906.7 KXZ53337.1 - 1.7 8.9 12.3 5.8 7.1 11.1 2.2 1 1 0 1 1 1 0 RING-variant domain Pkinase PF00069.25 KXZ53338.1 - 1.9e-24 86.5 0.0 5.3e-24 85.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53338.1 - 9.2e-15 54.6 0.0 1.9e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase TTRAP PF14203.6 KXZ53338.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Gcd10p PF04189.13 KXZ53340.1 - 3e-61 207.2 0.0 4.1e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family DUF1951 PF09188.10 KXZ53340.1 - 0.02 14.9 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) adh_short_C2 PF13561.6 KXZ53341.1 - 9.7e-61 205.3 0.1 1.8e-60 204.4 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ53341.1 - 1.1e-50 171.8 0.1 2.1e-50 170.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ53341.1 - 3.7e-11 43.3 0.3 6.9e-11 42.4 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXZ53341.1 - 0.0012 18.3 0.0 0.0056 16.1 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXZ53341.1 - 0.0015 18.1 0.2 0.0022 17.5 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_2 PF12796.7 KXZ53342.1 - 1e-27 96.5 20.8 9.3e-09 35.8 0.0 8.7 6 3 1 9 9 9 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ53342.1 - 2.3e-11 42.8 20.8 7.8 7.4 0.0 12.8 14 1 0 14 14 13 1 Ankyrin repeat Ank_5 PF13857.6 KXZ53342.1 - 3.6e-09 36.7 22.9 0.0038 17.5 0.2 8.3 6 3 3 9 9 9 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ53342.1 - 1.3e-07 32.0 22.0 0.034 14.7 0.0 9.9 10 4 2 12 12 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ53342.1 - 0.014 15.8 45.3 0.48 11.0 0.0 11.5 12 1 0 12 12 10 0 Ankyrin repeat NOA36 PF06524.12 KXZ53342.1 - 1.2 8.4 16.0 1.8 7.8 16.0 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KXZ53342.1 - 1.5 8.2 4.1 2.3 7.5 4.1 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 KXZ53342.1 - 1.6 7.8 17.8 0.069 12.3 12.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 KXZ53342.1 - 4.5 6.9 14.6 8.1 6.1 14.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 KXZ53342.1 - 5.4 7.2 13.1 10 6.3 13.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 KXZ53342.1 - 5.8 6.9 5.3 11 6.0 5.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KXZ53342.1 - 7.9 6.9 22.3 18 5.8 22.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 KXZ53342.1 - 9.4 4.3 6.2 13 3.8 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family Ank_4 PF13637.6 KXZ53343.1 - 1.7e-05 25.3 0.1 0.69 10.6 0.0 4.3 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ53343.1 - 0.08 13.5 0.0 1.8 9.2 0.0 2.9 2 1 0 3 3 3 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ53343.1 - 0.14 12.5 0.4 79 3.7 0.0 4.0 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Nup54 PF13874.6 KXZ53344.1 - 7e-21 74.8 3.3 1e-20 74.3 3.3 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KXZ53344.1 - 2e-06 28.5 62.0 0.00022 22.0 20.8 3.5 1 1 2 3 3 3 3 Nucleoporin FG repeat region Exonuc_VII_L PF02601.15 KXZ53344.1 - 0.25 10.9 3.3 0.37 10.3 3.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 KXZ53344.1 - 0.4 9.2 2.3 0.49 8.9 2.3 1.1 1 0 0 1 1 1 0 Macoilin family ABC_tran_CTD PF16326.5 KXZ53344.1 - 1.6 9.1 3.7 11 6.3 0.2 3.1 1 1 2 3 3 3 0 ABC transporter C-terminal domain MbeD_MobD PF04899.12 KXZ53344.1 - 1.9 8.7 5.6 13 6.0 0.2 2.5 1 1 0 2 2 2 0 MbeD/MobD like TBCC PF07986.12 KXZ53345.1 - 1.3e-23 83.0 0.0 2.2e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KXZ53345.1 - 0.099 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal mTERF PF02536.14 KXZ53346.1 - 6.2e-17 61.5 0.0 8.8e-10 38.0 0.0 2.4 1 1 1 2 2 2 2 mTERF HTH_31 PF13560.6 KXZ53346.1 - 0.023 15.0 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain ARD PF03079.14 KXZ53347.1 - 1.1e-55 188.2 0.0 1.3e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KXZ53347.1 - 2.6e-08 33.4 0.1 6.5e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXZ53347.1 - 1.8e-05 24.7 0.1 3.1e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXZ53347.1 - 0.0004 20.0 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Cupin SlyX PF04102.12 KXZ53348.1 - 0.0087 16.7 3.1 0.0087 16.7 3.1 13.9 10 5 4 14 14 14 2 SlyX Spc7 PF08317.11 KXZ53348.1 - 4 6.2 123.7 0.024 13.5 6.4 9.0 4 2 5 9 9 9 0 Spc7 kinetochore protein FPP PF05911.11 KXZ53348.1 - 6.5 4.8 87.7 0.0076 14.5 1.1 7.0 4 1 3 7 7 7 0 Filament-like plant protein, long coiled-coil HOOK PF05622.12 KXZ53348.1 - 7 4.7 103.2 0.29 9.2 7.6 5.7 4 1 1 5 5 5 0 HOOK protein DPM3 PF08285.11 KXZ53348.1 - 7.1 6.9 6.0 7.8 6.8 0.4 3.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RNA_pol_Rpb2_6 PF00562.28 KXZ53350.1 - 5.6e-119 397.7 0.0 7.4e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXZ53350.1 - 2.6e-53 180.5 0.0 3.6e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KXZ53350.1 - 2.7e-28 98.2 0.0 8.8e-28 96.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KXZ53350.1 - 3.1e-21 75.3 0.0 6.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KXZ53350.1 - 1.4e-20 73.3 0.8 3.6e-20 72.0 0.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 KXZ53350.1 - 9.4e-18 64.5 0.0 2.3e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 KXZ53350.1 - 1.7e-10 41.3 0.2 4.5e-10 39.9 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 EF-hand_1 PF00036.32 KXZ53352.1 - 9.1e-05 21.7 0.2 0.00017 20.9 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ53352.1 - 0.00035 19.9 0.5 0.00062 19.2 0.5 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ53352.1 - 0.0076 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ53352.1 - 0.048 14.1 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair PBP_N PF17093.5 KXZ53352.1 - 0.13 12.5 0.2 0.32 11.3 0.1 1.6 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Pkinase PF00069.25 KXZ53357.1 - 1.4e-07 31.2 0.0 4.4e-05 23.0 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53357.1 - 7e-07 28.8 0.0 0.038 13.3 0.0 3.0 1 1 1 2 2 2 2 Protein tyrosine kinase AAA_12 PF13087.6 KXZ53358.1 - 1e-35 123.2 0.0 1.8e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ53358.1 - 8.4e-17 61.8 0.0 4.5e-11 43.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXZ53358.1 - 2.5e-10 40.4 0.0 1.3e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ53358.1 - 1.2e-07 32.2 0.5 6.7e-07 29.7 0.0 2.5 4 0 0 4 4 3 1 AAA domain zf-met PF12874.7 KXZ53358.1 - 2.1e-05 24.8 13.1 0.0031 17.8 4.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type ResIII PF04851.15 KXZ53358.1 - 0.00017 21.7 0.0 0.00036 20.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2_4 PF13894.6 KXZ53358.1 - 0.0003 21.4 8.7 0.0034 18.1 3.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger Helicase_RecD PF05127.14 KXZ53358.1 - 0.00072 19.5 0.1 0.019 14.8 0.0 3.0 1 1 1 2 2 2 1 Helicase PhoH PF02562.16 KXZ53358.1 - 0.00083 18.9 0.0 0.0024 17.3 0.0 1.9 1 1 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 KXZ53358.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KXZ53358.1 - 0.0055 16.5 0.0 0.051 13.4 0.1 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KXZ53358.1 - 0.0065 16.7 0.1 0.14 12.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KXZ53358.1 - 0.02 14.3 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KXZ53358.1 - 0.027 14.2 0.0 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AKAP95 PF04988.12 KXZ53358.1 - 0.046 14.0 0.3 0.046 14.0 0.3 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) AAA_16 PF13191.6 KXZ53358.1 - 0.048 14.1 0.4 0.53 10.6 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain zf-C2H2_2 PF12756.7 KXZ53358.1 - 0.052 13.9 10.1 0.28 11.5 1.6 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2075 PF09848.9 KXZ53358.1 - 0.096 11.9 0.0 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KXZ53358.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ53358.1 - 0.11 12.5 0.0 0.39 10.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) FR47 PF08445.10 KXZ53358.1 - 0.14 12.1 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein RecR PF02132.15 KXZ53358.1 - 0.16 11.5 0.3 11 5.7 0.1 2.6 2 0 0 2 2 2 0 RecR protein zf-C2H2_jaz PF12171.8 KXZ53358.1 - 0.76 10.1 8.4 0.77 10.1 1.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding COG2 PF06148.11 KXZ53359.1 - 0.37 10.9 0.2 0.37 10.9 0.2 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.25 KXZ53360.1 - 1.7e-28 99.8 0.0 8.4e-28 97.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53360.1 - 8.9e-18 64.5 0.0 1.3e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NHL PF01436.21 KXZ53361.1 - 2.9e-23 80.6 19.6 0.00014 21.8 0.5 6.4 6 0 0 6 6 6 5 NHL repeat BTB PF00651.31 KXZ53361.1 - 4.5e-17 62.3 0.0 9.3e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SGL PF08450.12 KXZ53361.1 - 4.7e-07 29.6 0.2 6.3e-06 25.9 0.2 3.0 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 KXZ53361.1 - 0.0096 15.9 0.3 7.9 6.6 0.0 3.0 3 0 0 3 3 3 2 Beta-propeller repeat Ldl_recept_b PF00058.17 KXZ53361.1 - 0.65 10.5 3.2 1e+02 3.5 0.3 4.3 5 0 0 5 5 5 0 Low-density lipoprotein receptor repeat class B Telomere_Sde2_2 PF13297.6 KXZ53362.1 - 0.17 11.6 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Telomere stability C-terminal AAA_12 PF13087.6 KXZ53363.1 - 3.6e-47 160.6 0.0 5.4e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ53363.1 - 1.2e-24 87.5 0.0 7.3e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXZ53363.1 - 5.4e-15 55.6 0.0 2.6e-14 53.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXZ53363.1 - 1.3e-11 45.0 0.0 7.5e-11 42.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain zf-C2H2_2 PF12756.7 KXZ53363.1 - 1.8e-05 25.0 0.2 0.075 13.4 0.0 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) PhoH PF02562.16 KXZ53363.1 - 2e-05 24.2 0.0 0.0041 16.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.21 KXZ53363.1 - 2.1e-05 24.2 0.0 0.00073 19.2 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KXZ53363.1 - 3.9e-05 23.7 0.0 8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-met PF12874.7 KXZ53363.1 - 9.3e-05 22.7 0.7 0.41 11.1 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KXZ53363.1 - 0.00019 22.0 0.8 0.027 15.3 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXZ53363.1 - 0.0002 21.5 0.1 0.013 15.8 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Viral_helicase1 PF01443.18 KXZ53363.1 - 0.0013 18.5 0.0 1.1 8.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KXZ53363.1 - 0.0022 17.8 0.0 0.043 13.6 0.1 2.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KXZ53363.1 - 0.0038 17.5 0.1 0.055 13.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain Helicase_RecD PF05127.14 KXZ53363.1 - 0.0066 16.3 0.1 0.037 13.9 0.0 2.2 2 0 0 2 2 2 1 Helicase Mg_chelatase PF01078.21 KXZ53363.1 - 0.016 14.6 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 KXZ53363.1 - 0.03 13.5 0.0 0.46 9.6 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AKAP95 PF04988.12 KXZ53363.1 - 0.061 13.6 0.1 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 KXZ53363.1 - 0.074 13.5 0.8 2.6 8.7 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA PF00004.29 KXZ53363.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ53363.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ53363.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.5 5 1 0 5 5 3 0 AAA ATPase domain zf-DBF PF07535.12 KXZ53363.1 - 0.22 11.7 0.2 5.8 7.1 0.0 2.3 2 0 0 2 2 2 0 DBF zinc finger Usp PF00582.26 KXZ53365.1 - 5.1e-21 75.7 0.1 6.3e-21 75.4 0.1 1.0 1 0 0 1 1 1 1 Universal stress protein family zf-C2H2_3 PF13878.6 KXZ53366.1 - 2.1e-13 49.8 0.1 3.5e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.6 KXZ53366.1 - 1.5e-10 40.9 0.1 2.9e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 KXZ53366.1 - 0.06 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Usp PF00582.26 KXZ53367.1 - 2.5e-21 76.7 0.0 2.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family PRK PF00485.18 KXZ53368.1 - 9.2e-05 22.3 0.0 0.00033 20.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KXZ53368.1 - 0.0009 19.7 0.4 0.0015 18.9 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KXZ53368.1 - 0.0038 17.0 1.2 0.026 14.2 0.1 2.1 1 1 0 2 2 2 1 AAA domain MeaB PF03308.16 KXZ53368.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 KXZ53368.1 - 0.072 12.3 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.14 KXZ53368.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KXZ53368.1 - 0.09 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KXZ53368.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KXZ53368.1 - 0.2 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXZ53368.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Mito_fiss_reg PF05308.11 KXZ53369.1 - 0.15 12.1 1.9 0.17 11.9 1.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXZ53369.1 - 4.1 6.8 6.5 5 6.5 6.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mucin PF01456.17 KXZ53372.1 - 2.1 8.4 23.3 2.2 8.3 23.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 KXZ53372.1 - 8.8 4.4 17.7 7.5 4.6 17.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4281 PF14108.6 KXZ53373.1 - 3.2e-32 111.6 5.0 3.7e-32 111.4 5.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) DUF4281 PF14108.6 KXZ53374.1 - 1.6e-33 115.7 6.5 1.9e-33 115.5 6.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) PspB PF06667.12 KXZ53374.1 - 0.34 11.0 1.4 0.7 10.0 0.1 2.1 2 0 0 2 2 2 0 Phage shock protein B DUF4281 PF14108.6 KXZ53375.1 - 1.9e-29 102.6 7.6 2.2e-29 102.4 7.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) PspB PF06667.12 KXZ53375.1 - 0.92 9.6 3.1 9.2 6.4 0.1 2.4 2 0 0 2 2 2 0 Phage shock protein B NAD_binding_10 PF13460.6 KXZ53376.1 - 6.4e-20 71.8 9.9 2.4e-16 60.2 7.7 2.1 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 KXZ53376.1 - 1.8e-10 40.8 6.0 2.9e-10 40.1 4.7 1.7 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 KXZ53376.1 - 0.00034 20.9 0.8 0.00065 19.9 0.8 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 KXZ53376.1 - 0.0013 18.2 0.7 0.0018 17.8 0.7 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KXZ53376.1 - 0.0069 16.5 1.5 0.016 15.3 1.5 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus IlvN PF07991.12 KXZ53376.1 - 0.017 14.7 0.2 0.031 13.9 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3Beta_HSD PF01073.19 KXZ53376.1 - 0.025 13.6 0.3 0.034 13.1 0.3 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KXZ53376.1 - 0.21 12.0 1.3 0.54 10.7 1.3 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KXZ53377.1 - 2.4e-30 105.8 4.1 3.1e-30 105.4 4.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXZ53377.1 - 1.9e-16 60.4 0.4 2.8e-16 59.8 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXZ53377.1 - 0.00015 21.3 1.2 0.00038 20.0 1.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXZ53377.1 - 0.00066 19.9 0.3 0.0013 18.9 0.3 1.6 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 KXZ53377.1 - 0.015 14.9 0.3 0.034 13.7 0.3 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DapB_N PF01113.20 KXZ53377.1 - 0.026 14.6 0.5 0.047 13.8 0.4 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PLATZ PF04640.14 KXZ53378.1 - 1.4 9.6 13.0 0.81 10.3 0.6 3.0 3 1 0 3 3 3 0 PLATZ transcription factor Ricin_B_lectin PF00652.22 KXZ53379.1 - 1.3e-06 28.7 0.1 3.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXZ53379.1 - 0.079 13.7 0.1 3.1 8.6 0.0 3.3 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like PAN_4 PF14295.6 KXZ53379.1 - 0.18 11.7 6.7 4.2 7.4 0.0 3.9 4 0 0 4 4 4 0 PAN domain Ricin_B_lectin PF00652.22 KXZ53380.1 - 6.3e-07 29.7 0.2 1.5e-06 28.5 0.2 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXZ53380.1 - 0.014 16.1 0.4 0.93 10.3 0.1 3.1 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like PAN_4 PF14295.6 KXZ53380.1 - 0.027 14.4 4.0 19 5.2 0.1 4.2 4 0 0 4 4 4 0 PAN domain NAD_binding_8 PF13450.6 KXZ53383.1 - 7.2e-15 55.0 0.2 7.2e-15 55.0 0.2 3.3 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXZ53383.1 - 1.3e-08 34.6 0.1 1.3e-08 34.6 0.1 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KXZ53383.1 - 7.5e-05 22.1 0.7 0.00017 21.0 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ53383.1 - 0.00018 21.0 0.7 0.00018 21.0 0.7 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXZ53383.1 - 0.0044 15.8 0.2 0.0065 15.2 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXZ53383.1 - 0.034 13.4 0.5 0.065 12.5 0.5 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KXZ53383.1 - 0.04 13.0 1.2 0.088 11.9 1.2 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KXZ53383.1 - 0.12 12.9 1.3 0.23 12.1 1.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Bindin PF02084.15 KXZ53385.1 - 0.0002 21.7 3.4 0.00024 21.5 3.4 1.0 1 0 0 1 1 1 1 Bindin NOA36 PF06524.12 KXZ53385.1 - 0.042 13.2 5.4 0.047 13.0 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 KXZ53385.1 - 0.075 12.8 1.5 0.087 12.6 1.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PBP1_TM PF14812.6 KXZ53385.1 - 0.11 12.9 17.5 0.077 13.4 12.9 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 KXZ53385.1 - 0.11 12.3 5.4 0.16 11.7 5.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 KXZ53385.1 - 0.17 11.0 3.2 0.17 11.0 3.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FXMRP1_C_core PF12235.8 KXZ53385.1 - 0.64 10.7 15.6 1 10.0 15.6 1.4 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal FAM176 PF14851.6 KXZ53385.1 - 1.1 8.9 7.5 1.4 8.6 5.8 1.8 2 0 0 2 2 2 0 FAM176 family Cwf_Cwc_15 PF04889.12 KXZ53385.1 - 1.7 8.3 14.8 2.1 8.0 14.8 1.2 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KXZ53385.1 - 1.9 6.5 11.6 2.4 6.1 11.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi VIT1 PF01988.19 KXZ53385.1 - 3.2 7.6 4.0 4.6 7.1 4.0 1.2 1 0 0 1 1 1 0 VIT family CENP-B_dimeris PF09026.10 KXZ53385.1 - 3.8 8.0 16.7 1.2 9.5 13.6 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pep1_7 PF17232.2 KXZ53385.1 - 5.5 7.5 8.0 1.2e+02 3.3 0.0 2.4 2 1 0 2 2 2 0 Elicitor peptide 1-7 CDC45 PF02724.14 KXZ53385.1 - 6.5 4.9 7.5 8.8 4.5 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S9_N PF02897.15 KXZ53386.1 - 1.1e-43 149.6 0.0 1.4e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KXZ53387.1 - 1.3e-27 96.7 0.0 1.7e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Rhodanese PF00581.20 KXZ53388.1 - 2.8e-11 43.9 0.0 4.5e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Acylphosphatase PF00708.18 KXZ53389.1 - 1.5e-25 89.4 0.1 1.6e-25 89.3 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase Tyr_Deacylase PF02580.16 KXZ53390.1 - 2.5e-31 109.1 0.0 4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF1631 PF07793.11 KXZ53390.1 - 0.29 9.5 3.3 0.36 9.2 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) F-box-like PF12937.7 KXZ53391.1 - 1.1e-05 25.2 0.3 1.1e-05 25.2 0.3 2.0 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KXZ53391.1 - 9e-05 22.2 0.0 0.00024 20.9 0.0 1.7 1 1 0 1 1 1 1 F-box domain Sulfotransfer_3 PF13469.6 KXZ53392.1 - 0.036 14.4 1.1 0.089 13.2 1.1 1.8 1 1 0 1 1 1 0 Sulfotransferase family zf-C2HC_2 PF13913.6 KXZ53392.1 - 0.14 12.1 0.3 0.22 11.5 0.3 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FAST_1 PF06743.15 KXZ53393.1 - 0.00012 22.0 0.0 0.011 15.7 0.0 3.2 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 1 DUF2894 PF11445.8 KXZ53393.1 - 0.33 11.4 0.1 0.33 11.4 0.1 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2894) zf-HC2 PF13490.6 KXZ53393.1 - 4.1 7.7 5.6 3.4 8.0 0.1 3.5 3 0 0 3 3 3 0 Putative zinc-finger Ank_2 PF12796.7 KXZ53396.1 - 6e-11 42.8 0.1 0.014 16.0 0.1 4.0 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53396.1 - 2e-08 34.6 1.4 1 10.0 0.0 6.1 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ53396.1 - 2.6e-05 24.4 0.8 1.1 9.7 0.0 5.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53396.1 - 0.0016 18.7 0.1 17 6.4 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat Ysc84 PF04366.12 KXZ53398.1 - 5.6e-05 22.9 1.2 8.4e-05 22.3 1.2 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ribosomal_60s PF00428.19 KXZ53398.1 - 0.033 14.8 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein UPF0004 PF00919.20 KXZ53400.1 - 7.7e-31 106.1 0.3 1.6e-30 105.1 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KXZ53400.1 - 1.2e-25 90.8 0.1 2.1e-25 90.1 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 KXZ53400.1 - 1.4e-12 47.4 0.0 5.2e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 TRAM domain Lipase_GDSL_2 PF13472.6 KXZ53400.1 - 0.0014 19.0 0.0 0.0084 16.5 0.0 2.2 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TRAM_2 PF18693.1 KXZ53400.1 - 0.0055 16.8 0.0 0.029 14.5 0.0 2.3 1 1 0 1 1 1 1 TRAM domain DUF3781 PF12636.7 KXZ53400.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) RabGAP-TBC PF00566.18 KXZ53401.1 - 5.2e-11 42.6 0.0 7.8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Form_Nir_trans PF01226.17 KXZ53402.1 - 6.6e-72 241.7 30.9 7.7e-72 241.4 30.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Phage_tail_X PF05489.12 KXZ53402.1 - 0.72 9.6 4.7 1.8 8.3 0.2 2.9 3 0 0 3 3 3 0 Phage Tail Protein X OTU PF02338.19 KXZ53403.1 - 1.5e-11 44.9 0.0 1.9e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXZ53403.1 - 4.8e-05 22.9 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase C65 Otubain DTW PF03942.15 KXZ53404.1 - 1.8e-28 99.6 0.0 2.4e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 DTW domain CBM_10 PF02013.16 KXZ53405.1 - 0.00069 20.0 14.7 0.0098 16.3 2.2 4.4 4 0 0 4 4 4 4 Cellulose or protein binding domain CBM_10 PF02013.16 KXZ53406.1 - 0.16 12.4 36.7 1.1 9.8 0.3 7.8 7 0 0 7 7 7 0 Cellulose or protein binding domain DUF778 PF05608.12 KXZ53407.1 - 1.6e-10 41.7 0.0 1.9e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF778) DUF4796 PF16044.5 KXZ53407.1 - 0.023 14.3 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) HEAT_EZ PF13513.6 KXZ53408.1 - 0.19 12.3 2.7 0.86 10.2 0.5 2.5 2 0 0 2 2 2 0 HEAT-like repeat Abhydrolase_1 PF00561.20 KXZ53409.1 - 3.1e-21 76.2 0.1 5.7e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ53409.1 - 7e-15 56.2 13.5 1.5e-14 55.2 13.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ53409.1 - 6.8e-10 38.6 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXZ53409.1 - 0.028 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein PEX11 PF05648.14 KXZ53410.1 - 2.2e-39 135.2 0.6 2.5e-39 135.0 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HscB_4_cys PF18256.1 KXZ53411.1 - 0.0065 16.3 0.4 0.06 13.2 0.4 2.8 1 0 0 1 1 1 1 Co-chaperone HscB tetracysteine metal binding motif Rcd1 PF04078.13 KXZ53412.1 - 2.1e-75 253.4 0.3 2.4e-75 253.2 0.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DEAD PF00270.29 KXZ53413.1 - 4.2e-26 91.8 0.0 1.5e-18 67.1 0.0 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ53413.1 - 9.9e-25 87.1 0.0 2.1e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Lectin_C PF00059.21 KXZ53414.1 - 5.4e-06 27.1 0.0 2.1 9.1 0.0 4.6 4 2 0 4 4 4 3 Lectin C-type domain DUF5011 PF16403.5 KXZ53417.1 - 1.2e-18 67.0 0.2 3.1e-05 24.0 0.0 5.8 7 0 0 7 7 7 4 Domain of unknown function (DUF5011) PKD_channel PF08016.12 KXZ53417.1 - 1.7e-09 36.9 5.5 3.9e-09 35.7 5.4 1.5 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KXZ53417.1 - 0.0011 18.3 2.8 0.0018 17.6 2.8 1.2 1 0 0 1 1 1 1 Ion transport protein Big_3_4 PF13754.6 KXZ53417.1 - 0.015 15.0 0.0 0.83 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function Lectin_C PF00059.21 KXZ53417.1 - 0.15 12.8 0.0 31 5.4 0.0 3.2 2 1 0 2 2 2 0 Lectin C-type domain Lectin_C PF00059.21 KXZ53419.1 - 4.9e-09 36.9 0.0 0.3 11.8 0.0 5.7 5 1 0 5 5 5 3 Lectin C-type domain Lectin_C PF00059.21 KXZ53420.1 - 6.1e-05 23.7 0.0 9.3 7.0 0.0 4.0 3 1 1 4 4 4 3 Lectin C-type domain DUF5011 PF16403.5 KXZ53422.1 - 2.9e-16 59.3 0.0 0.0012 18.9 0.0 5.6 5 1 0 5 5 5 4 Domain of unknown function (DUF5011) Caskin-Pro-rich PF16907.5 KXZ53422.1 - 0.021 15.4 0.5 0.085 13.4 0.5 2.1 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Big_3_4 PF13754.6 KXZ53422.1 - 0.027 14.2 0.0 0.95 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function Got1 PF04178.12 KXZ53422.1 - 0.12 12.8 0.9 0.27 11.6 0.9 1.6 1 0 0 1 1 1 0 Got1/Sft2-like family YycC PF14174.6 KXZ53422.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein HicB_lk_antitox PF15919.5 KXZ53423.1 - 3.9e-08 33.4 0.0 6e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system cNMP_binding PF00027.29 KXZ53424.1 - 4.2e-14 52.4 0.1 3.3e-05 23.9 0.0 4.8 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain TMEM70 PF06979.12 KXZ53426.1 - 9.9e-19 68.1 0.0 1.3e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex TMEM223 PF14640.6 KXZ53426.1 - 0.00049 20.3 0.0 0.00077 19.7 0.0 1.3 1 1 0 1 1 1 1 Transmembrane protein 223 Ceramidase PF05875.12 KXZ53426.1 - 0.029 13.8 0.1 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Ceramidase CHZ PF09649.10 KXZ53427.1 - 2.2e-07 30.2 0.4 2.2e-07 30.2 0.4 2.8 2 0 0 2 2 2 1 Histone chaperone domain CHZ Cu2_monooxygen PF01082.20 KXZ53429.1 - 1.6e-25 89.9 0.3 3.4e-20 72.6 0.1 2.3 2 0 0 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KXZ53429.1 - 2.2e-12 46.8 0.0 9.5e-11 41.4 0.0 2.3 1 1 1 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 KXZ53429.1 - 4.8e-09 36.5 0.0 8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Na_H_Exchanger PF00999.21 KXZ53431.1 - 1.1e-17 63.9 25.7 4.2e-11 42.2 13.6 2.7 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family LRR_4 PF12799.7 KXZ53433.1 - 0.019 15.4 1.1 1.8 9.1 0.0 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) B3R PF17057.5 KXZ53433.1 - 0.032 14.4 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Poxviridae B3 protein LRR_8 PF13855.6 KXZ53433.1 - 0.45 10.3 2.7 5.2 6.9 0.1 3.9 5 0 0 5 5 5 0 Leucine rich repeat B3R PF17057.5 KXZ53434.1 - 0.019 15.2 0.0 0.052 13.8 0.0 1.7 2 0 0 2 2 2 0 Poxviridae B3 protein LRR_4 PF12799.7 KXZ53434.1 - 0.057 13.9 1.3 1.5 9.3 0.0 3.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ53434.1 - 0.079 12.7 1.0 2.2 8.1 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat Robl_LC7 PF03259.17 KXZ53434.1 - 0.14 11.9 0.1 26 4.7 0.0 2.5 2 0 0 2 2 2 0 Roadblock/LC7 domain Pyr_redox_2 PF07992.14 KXZ53435.1 - 5.4e-41 140.7 0.4 9.7e-41 139.9 0.4 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ53435.1 - 2.3e-17 63.3 0.0 5.3e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ53435.1 - 4.9e-08 32.6 0.1 2.6e-06 26.9 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXZ53435.1 - 3.5e-07 30.3 3.9 0.58 10.1 0.0 4.2 2 2 2 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXZ53435.1 - 5.7e-07 28.9 3.5 0.00048 19.3 0.5 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KXZ53435.1 - 8.1e-06 25.6 5.6 0.28 10.7 0.0 3.3 2 1 1 3 3 3 3 FAD dependent oxidoreductase HI0933_like PF03486.14 KXZ53435.1 - 2.8e-05 23.0 1.0 0.0057 15.4 0.5 2.8 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 KXZ53435.1 - 9.6e-05 22.8 0.2 0.3 11.5 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KXZ53435.1 - 0.00021 21.5 4.4 0.35 11.1 0.2 3.3 4 0 0 4 4 3 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ53435.1 - 0.0018 17.4 4.7 0.17 11.0 2.2 2.4 2 1 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KXZ53435.1 - 0.0031 16.7 0.8 0.0031 16.7 0.8 3.1 3 1 1 4 4 4 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXZ53435.1 - 0.005 15.7 2.5 0.63 8.8 0.8 3.0 3 0 0 3 3 3 1 Tryptophan halogenase FAD_oxidored PF12831.7 KXZ53435.1 - 0.0086 15.5 6.5 0.055 12.8 2.6 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KXZ53435.1 - 0.01 16.1 0.1 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Catalase_C PF18011.1 KXZ53435.1 - 0.028 14.1 0.4 0.053 13.2 0.4 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases BMC PF00936.19 KXZ53435.1 - 0.046 13.7 1.4 0.15 12.1 0.6 2.2 2 0 0 2 2 2 0 BMC domain K_oxygenase PF13434.6 KXZ53435.1 - 0.056 12.6 0.5 0.16 11.1 0.1 1.8 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KXZ53435.1 - 0.07 12.4 3.2 2.7 7.1 1.2 2.5 2 1 1 3 3 3 0 FAD binding domain CoA_binding_2 PF13380.6 KXZ53435.1 - 0.092 13.2 0.2 14 6.2 0.0 2.6 1 1 1 2 2 2 0 CoA binding domain DUF3236 PF11576.8 KXZ53435.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) SHIPPO-rpt PF07004.12 KXZ53437.1 - 5.1 8.2 26.1 8.5 7.5 1.5 4.7 4 1 0 4 4 4 0 Sperm-tail PG-rich repeat ETF PF01012.21 KXZ53438.1 - 0.0001 22.3 0.1 0.00013 21.9 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PPR_2 PF13041.6 KXZ53439.1 - 7.6e-10 38.8 2.2 0.00071 19.7 0.1 4.3 2 2 3 5 5 5 4 PPR repeat family PPR_long PF17177.4 KXZ53439.1 - 4.9e-07 29.3 0.5 9e-07 28.5 0.2 1.5 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KXZ53439.1 - 4.2e-06 26.6 0.4 8.3 6.9 0.0 4.2 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KXZ53439.1 - 2.7e-05 24.1 0.1 0.0014 18.6 0.0 2.5 2 1 0 2 2 2 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXZ53439.1 - 0.0012 18.5 0.1 1.9 8.3 0.0 3.9 4 0 0 4 4 4 1 PPR repeat BTAD PF03704.17 KXZ53439.1 - 0.018 15.5 0.4 0.018 15.5 0.4 2.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain NTase_sub_bind PF08780.11 KXZ53440.1 - 0.14 12.1 1.3 0.34 10.9 0.2 2.1 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like adh_short PF00106.25 KXZ53441.1 - 6.6e-17 61.6 0.1 1.9e-09 37.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ53441.1 - 3.5e-12 46.4 0.0 7.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DEC-1_N PF04625.13 KXZ53441.1 - 0.28 10.1 2.8 0.33 9.9 2.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TPR_19 PF14559.6 KXZ53443.1 - 0.0013 19.2 0.5 0.0013 19.2 0.5 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ53443.1 - 0.0038 17.4 0.2 0.0071 16.5 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXZ53443.1 - 0.0054 17.0 0.8 0.011 16.1 0.8 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ53443.1 - 0.026 14.8 0.5 0.026 14.8 0.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ53443.1 - 5.4 7.9 6.5 0.48 11.2 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CAAD PF14159.6 KXZ53445.1 - 4.2e-15 55.3 0.5 7.2e-15 54.6 0.5 1.4 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase RRF PF01765.19 KXZ53446.1 - 5.4e-26 91.5 0.0 1.1e-25 90.5 0.0 1.4 1 1 0 1 1 1 1 Ribosome recycling factor NACHT PF05729.12 KXZ53447.1 - 2.9e-05 24.1 0.2 0.00021 21.2 0.1 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXZ53447.1 - 0.00061 20.2 0.3 0.013 15.8 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXZ53447.1 - 0.006 16.9 0.0 0.041 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXZ53447.1 - 0.0061 16.5 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXZ53447.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXZ53447.1 - 0.021 15.3 0.1 0.066 13.6 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EF-hand_7 PF13499.6 KXZ53447.1 - 0.029 14.8 0.2 0.19 12.2 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain pair PSK_trans_fac PF07704.11 KXZ53447.1 - 0.037 14.8 0.1 0.037 14.8 0.1 1.8 2 0 0 2 2 1 0 Rv0623-like transcription factor IstB_IS21 PF01695.17 KXZ53447.1 - 0.048 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KXZ53447.1 - 0.049 13.9 2.4 0.082 13.1 0.2 2.4 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.22 KXZ53447.1 - 0.065 12.4 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain EF-hand_6 PF13405.6 KXZ53447.1 - 0.08 12.9 0.1 0.63 10.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain ATPase PF06745.13 KXZ53447.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KXZ53447.1 - 0.13 11.8 0.0 0.41 10.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXZ53447.1 - 0.24 11.8 0.5 2.3 8.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain Aminotran_1_2 PF00155.21 KXZ53448.1 - 2.9e-81 273.5 0.0 9.2e-80 268.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II 60KD_IMP PF02096.20 KXZ53449.1 - 6.9e-46 156.2 0.0 8.6e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2062 PF09835.9 KXZ53449.1 - 0.064 13.1 1.1 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) TPR_9 PF13371.6 KXZ53450.1 - 0.00028 21.0 3.1 0.00047 20.2 3.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ53450.1 - 0.003 18.2 6.2 0.0071 17.1 6.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ53450.1 - 0.0064 16.3 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ53450.1 - 0.012 15.7 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ53450.1 - 0.036 14.6 2.4 0.078 13.5 1.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ53450.1 - 0.096 11.9 1.1 0.13 11.5 1.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ53450.1 - 0.1 13.3 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ53450.1 - 0.16 12.3 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP_N PF01213.19 KXZ53450.1 - 0.25 10.8 5.3 0.31 10.5 5.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_3 PF01494.19 KXZ53451.1 - 9.3e-13 48.1 1.4 6.5e-12 45.4 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXZ53451.1 - 1.1e-05 25.6 0.1 4.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ53451.1 - 0.00019 21.2 0.4 0.00037 20.2 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KXZ53451.1 - 0.00025 20.6 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 KXZ53451.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ53451.1 - 0.0027 17.0 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ53451.1 - 0.0041 15.9 0.0 0.0053 15.5 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXZ53451.1 - 0.029 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KXZ53451.1 - 0.043 14.4 0.0 0.096 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXZ53451.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fructosamin_kin PF03881.14 KXZ53452.1 - 2.9e-76 256.4 0.0 3.4e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXZ53452.1 - 9.9e-09 35.5 0.0 1.4e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family FACT-Spt16_Nlob PF14826.6 KXZ53453.1 - 5.3e-44 149.9 0.0 9.2e-44 149.1 0.0 1.4 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KXZ53453.1 - 1.8e-41 141.8 0.1 5.9e-41 140.2 0.0 1.9 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KXZ53453.1 - 2e-28 99.5 0.0 3.6e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rubis-subs-bind PF09273.11 KXZ53453.1 - 1.4e-15 58.2 0.0 3.7e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Rtt106 PF08512.12 KXZ53453.1 - 4e-14 52.8 0.0 7.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Abhydro_lipase PF04083.16 KXZ53453.1 - 3.8e-13 48.8 0.0 7.7e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region SET PF00856.28 KXZ53453.1 - 7.8e-07 29.6 0.0 1.6e-05 25.4 0.0 2.7 2 0 0 2 2 2 1 SET domain CDC45 PF02724.14 KXZ53453.1 - 0.0036 15.7 11.8 0.0057 15.0 11.8 1.2 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 KXZ53453.1 - 0.0041 16.6 20.0 0.0083 15.6 20.0 1.4 1 0 0 1 1 1 1 SDA1 Hydrolase_4 PF12146.8 KXZ53453.1 - 0.12 11.6 4.6 0.14 11.4 0.1 2.7 2 1 0 2 2 1 0 Serine aminopeptidase, S33 FTR_C PF02741.15 KXZ53453.1 - 8.7 6.4 6.5 0.34 10.9 0.0 1.9 2 0 0 2 2 1 0 FTR, proximal lobe MCM PF00493.23 KXZ53454.1 - 2.5e-50 170.7 0.0 6.7e-50 169.3 0.0 1.6 1 1 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KXZ53454.1 - 7.8e-08 32.6 2.2 1e-07 32.3 1.3 1.6 2 0 0 2 2 2 1 MCM AAA-lid domain AAA_5 PF07728.14 KXZ53454.1 - 0.00049 20.1 0.0 0.0018 18.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXZ53454.1 - 0.0071 15.8 0.1 0.72 9.2 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 KXZ53454.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 KXZ53454.1 - 0.082 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_16 PF13191.6 KXZ53454.1 - 0.12 12.7 0.3 0.12 12.7 0.3 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXZ53454.1 - 0.14 12.5 0.2 0.33 11.2 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXZ53454.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region CRAL_TRIO PF00650.20 KXZ53455.1 - 2.7e-17 63.0 0.0 3.9e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXZ53455.1 - 0.00079 19.6 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RecX PF02631.16 KXZ53456.1 - 2.4e-15 57.1 0.0 1.1e-14 55.0 0.0 2.0 2 1 0 2 2 2 1 RecX family SelB-wing_2 PF09106.11 KXZ53456.1 - 0.11 12.7 2.1 3.6 7.9 2.1 2.7 1 1 0 1 1 1 0 Elongation factor SelB, winged helix DUF2017 PF09438.10 KXZ53457.1 - 0.009 15.9 0.2 0.027 14.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2017) FAST_1 PF06743.15 KXZ53458.1 - 0.16 11.9 0.0 5.2 7.1 0.0 2.6 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 1 Rdx PF10262.9 KXZ53459.1 - 0.077 13.2 0.0 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 Rdx family Herpes_capsid PF06112.11 KXZ53460.1 - 0.72 9.9 3.6 1.2 9.1 3.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RsfS PF02410.15 KXZ53462.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation UBA PF00627.31 KXZ53463.1 - 4.6e-09 36.0 0.0 0.00085 19.2 0.0 3.2 2 0 0 2 2 2 2 UBA/TS-N domain Ubiquitin_5 PF18037.1 KXZ53463.1 - 0.036 14.4 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Exostosin PF03016.15 KXZ53464.1 - 9.5e-55 185.9 0.0 1.2e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ53464.1 - 1.2e-06 28.7 50.8 0.0027 18.0 15.6 4.4 4 0 0 4 4 4 3 EGF-like domain DUF3300 PF11737.8 KXZ53464.1 - 0.15 11.5 0.5 0.28 10.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) Exostosin PF03016.15 KXZ53465.1 - 5.2e-57 193.3 0.0 7.2e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ53465.1 - 0.00027 21.2 48.9 0.0058 17.0 15.3 3.7 4 0 0 4 4 4 2 EGF-like domain Exostosin PF03016.15 KXZ53466.1 - 3.6e-54 184.0 0.0 5.6e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ53466.1 - 0.00017 21.8 14.7 0.00017 21.8 14.7 2.2 2 0 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 KXZ53466.1 - 0.0045 17.0 11.6 0.0087 16.1 11.6 1.5 1 0 0 1 1 1 1 Tenascin EGF domain I-EGF_1 PF18372.1 KXZ53466.1 - 0.8 9.8 7.1 1.7 8.8 7.1 1.5 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Exostosin PF03016.15 KXZ53467.1 - 4.3e-51 173.9 0.0 6.3e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Exostosin family WD40 PF00400.32 KXZ53468.1 - 1.6e-12 47.7 16.6 0.00037 21.3 0.1 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ53468.1 - 4.8e-11 42.8 1.8 0.016 15.5 0.0 5.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KXZ53468.1 - 2.8e-05 22.4 0.0 0.088 10.8 0.0 2.4 1 1 1 2 2 2 2 IKI3 family eIF2A PF08662.11 KXZ53468.1 - 3.8e-05 23.7 0.1 0.25 11.2 0.0 4.2 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXZ53468.1 - 0.00057 18.9 0.6 0.074 12.0 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KXZ53468.1 - 0.0062 15.6 0.4 0.43 9.6 0.1 3.2 3 0 0 3 3 3 1 Coatomer WD associated region AdoHcyase PF05221.17 KXZ53469.1 - 1.1e-144 481.2 0.0 1.2e-144 481.0 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KXZ53469.1 - 1.1e-81 272.7 1.0 1.5e-81 272.2 1.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXZ53469.1 - 9.8e-08 31.6 0.1 1.7e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KXZ53469.1 - 0.0033 17.0 0.1 0.0063 16.1 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KXZ53469.1 - 0.019 15.0 0.1 0.048 13.7 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXZ53469.1 - 0.059 13.8 0.1 0.2 12.1 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KXZ53469.1 - 0.15 12.4 0.3 0.49 10.7 0.1 2.1 2 1 0 2 2 2 0 TrkA-N domain Pkinase PF00069.25 KXZ53470.1 - 0.0042 16.5 0.0 0.0061 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CLP_protease PF00574.23 KXZ53471.1 - 1.2e-39 136.1 0.0 1.9e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Clp protease Rhomboid PF01694.22 KXZ53472.1 - 6.3e-15 55.5 5.2 8.1e-15 55.1 5.2 1.1 1 0 0 1 1 1 1 Rhomboid family Usp PF00582.26 KXZ53473.1 - 7.6e-22 78.3 0.0 1e-21 77.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family BACK PF07707.15 KXZ53474.1 - 0.00059 19.9 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch PfkB PF00294.24 KXZ53477.1 - 5.6e-71 239.3 0.0 6.4e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Pox_MCEL PF03291.16 KXZ53479.1 - 1.9e-16 60.1 0.0 4.9e-13 48.9 0.0 3.0 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KXZ53479.1 - 0.00043 20.9 0.0 0.00082 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ53479.1 - 0.00098 19.8 0.0 0.0034 18.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ53479.1 - 0.082 13.6 0.0 0.2 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Jiraiya PF15038.6 KXZ53480.1 - 0.046 13.2 2.4 5.2 6.5 0.1 2.6 2 0 0 2 2 2 0 Jiraiya Lung_7-TM_R PF06814.13 KXZ53480.1 - 0.078 12.2 4.1 0.56 9.4 0.2 2.2 2 0 0 2 2 2 0 Lung seven transmembrane receptor 7TMR-DISM_7TM PF07695.11 KXZ53480.1 - 0.15 12.0 10.4 1.2 8.9 4.0 2.4 2 0 0 2 2 2 0 7TM diverse intracellular signalling HNH_5 PF14279.6 KXZ53481.1 - 1.9e-10 40.5 1.0 6.1e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease HNH PF01844.23 KXZ53481.1 - 1.4e-08 34.7 0.0 3.3e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 KXZ53481.1 - 2.3e-06 27.4 0.3 3.9e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 HNH endonuclease PyrI_C PF02748.15 KXZ53481.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 KXZ53481.1 - 0.11 13.0 0.1 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Ufm1 PF03671.14 KXZ53482.1 - 8.8e-33 112.2 0.1 1e-32 112.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein PsbP PF01789.16 KXZ53484.1 - 0.083 13.0 0.2 0.2 11.8 0.2 1.7 2 1 0 2 2 2 0 PsbP PS_Dcarbxylase PF02666.15 KXZ53485.1 - 7.8e-34 117.0 0.0 1.2e-33 116.3 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase TPT PF03151.16 KXZ53486.1 - 1.4e-07 31.2 12.1 1.6e-07 31.0 12.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UPF0220 PF05255.11 KXZ53487.1 - 0.0044 16.6 2.6 0.0048 16.5 2.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DNA_pol_B_exo1 PF03104.19 KXZ53489.1 - 0.14 11.3 0.0 2.4 7.2 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase family B, exonuclease domain zf-TAZ PF02135.16 KXZ53490.1 - 1.5e-10 41.4 14.5 2.2e-10 40.8 14.5 1.2 1 0 0 1 1 1 1 TAZ zinc finger SPX PF03105.19 KXZ53490.1 - 0.27 11.1 0.1 0.33 10.8 0.1 1.1 1 0 0 1 1 1 0 SPX domain zf-TAZ PF02135.16 KXZ53491.1 - 1.1e-09 38.7 19.6 1.1e-09 38.7 19.6 2.6 3 0 0 3 3 3 1 TAZ zinc finger MAJIN PF15077.6 KXZ53491.1 - 0.89 9.3 15.7 2 8.2 15.7 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein Macoilin PF09726.9 KXZ53491.1 - 1.8 7.0 12.8 2.4 6.6 12.8 1.1 1 0 0 1 1 1 0 Macoilin family VIT1 PF01988.19 KXZ53491.1 - 2.7 7.8 7.1 6.3 6.6 7.1 1.6 1 0 0 1 1 1 0 VIT family GREB1 PF15782.5 KXZ53491.1 - 6 3.8 18.1 11 3.0 18.1 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Retrotran_gag_2 PF14223.6 KXZ53493.1 - 6e-17 61.6 0.0 7.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 KXZ53493.1 - 0.00075 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Zwint PF15556.6 KXZ53493.1 - 0.12 11.8 0.3 0.15 11.5 0.3 1.1 1 0 0 1 1 1 0 ZW10 interactor DUF4219 PF13961.6 KXZ53493.1 - 0.45 10.3 1.5 0.69 9.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) RVT_2 PF07727.14 KXZ53494.1 - 2.8e-71 240.0 0.0 3.2e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 KXZ53494.1 - 0.031 13.9 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Chlororespiratory reduction 6 Usp PF00582.26 KXZ53495.1 - 6.9e-24 85.0 1.2 5.9e-12 46.3 0.0 3.3 2 2 0 2 2 2 2 Universal stress protein family Ank_2 PF12796.7 KXZ53496.1 - 4.2e-07 30.5 0.0 2.5 8.8 0.0 4.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53496.1 - 0.00028 21.4 5.3 0.66 10.6 0.9 5.4 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53496.1 - 0.047 14.2 4.2 1e+02 4.0 0.0 6.1 7 0 0 7 7 7 0 Ankyrin repeat Ifi-6-16 PF06140.13 KXZ53496.1 - 1.2 9.1 13.3 0.11 12.4 2.0 3.6 3 0 0 3 3 3 0 Interferon-induced 6-16 family zf-MYND PF01753.18 KXZ53497.1 - 6.5e-07 29.3 11.0 1.2e-06 28.5 11.0 1.4 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 KXZ53498.1 - 1.4e-07 32.0 0.1 0.89 10.2 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53498.1 - 1.1e-05 25.8 6.4 13 6.5 0.0 6.3 4 3 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53498.1 - 0.00011 22.3 0.1 5 8.0 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat F-box PF00646.33 KXZ53498.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain Ifi-6-16 PF06140.13 KXZ53498.1 - 8.9 6.3 11.6 0.2 11.6 1.5 3.0 3 0 0 3 3 3 0 Interferon-induced 6-16 family zf-MYND PF01753.18 KXZ53500.1 - 4.5e-10 39.5 10.1 7e-10 38.8 10.1 1.4 1 0 0 1 1 1 1 MYND finger AMP-binding PF00501.28 KXZ53501.1 - 2.5e-50 171.3 0.1 1.4e-39 135.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ53501.1 - 4e-19 69.4 0.1 8.5e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ubiquitin PF00240.23 KXZ53504.1 - 4.9e-21 74.3 0.1 7.3e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 KXZ53504.1 - 5.4e-21 75.1 0.0 7.9e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53504.1 - 2.3e-11 43.5 0.0 3.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rad60-SLD PF11976.8 KXZ53504.1 - 3.6e-10 39.5 0.3 5.2e-10 39.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Kinase-like PF14531.6 KXZ53504.1 - 4.9e-07 29.4 0.0 8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like AAA_12 PF13087.6 KXZ53505.1 - 3.9e-33 114.8 0.0 1e-32 113.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ53505.1 - 1.1e-21 77.8 0.1 1.1e-11 45.0 0.4 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KXZ53505.1 - 6.2e-05 22.4 0.9 0.058 12.6 0.1 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXZ53505.1 - 0.00014 21.4 0.5 0.0013 18.2 0.2 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 KXZ53505.1 - 0.0031 17.9 4.7 0.23 11.8 0.4 3.2 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KXZ53505.1 - 0.071 12.8 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 KXZ53505.1 - 0.081 12.0 0.2 0.35 9.9 0.0 2.1 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.6 KXZ53505.1 - 0.098 12.9 5.3 9.4 6.5 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 KXZ53505.1 - 0.11 12.9 0.4 2.4 8.6 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ53505.1 - 0.51 10.7 0.0 0.51 10.7 0.0 5.3 6 0 0 6 6 6 0 AAA ATPase domain Ank_2 PF12796.7 KXZ53506.1 - 4e-12 46.6 0.3 0.005 17.4 0.0 4.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53506.1 - 0.00019 21.9 8.5 0.37 11.4 0.2 5.9 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ53506.1 - 0.00034 20.9 10.6 0.72 10.3 0.3 6.3 5 3 3 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53506.1 - 0.0024 18.2 10.9 9.3 7.2 0.0 8.0 9 2 2 11 11 11 2 Ankyrin repeat Ank PF00023.30 KXZ53506.1 - 0.079 13.4 2.1 13 6.5 0.1 4.4 5 1 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 KXZ53507.1 - 8.7e-13 48.7 0.0 0.00024 21.6 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53507.1 - 3.8e-07 30.5 1.1 1.1 9.9 0.1 5.5 4 3 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53507.1 - 7.7e-06 25.9 4.9 0.38 11.4 0.0 6.0 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KXZ53507.1 - 5.2e-05 23.4 6.3 0.52 10.7 0.0 5.7 4 2 1 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ53507.1 - 0.0049 17.2 1.3 3.5 8.2 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeat DUF2336 PF10098.9 KXZ53507.1 - 0.19 11.2 9.0 0.11 12.0 0.2 3.0 4 0 0 4 4 4 0 Uncharacterised protein conserved in bacteria (DUF2336) SNF2_N PF00176.23 KXZ53508.1 - 3.8e-47 160.7 0.0 5.4e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ53508.1 - 2.4e-14 53.6 0.0 3.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXZ53508.1 - 3.1e-09 36.5 10.4 8.4e-09 35.1 10.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ53508.1 - 5.1e-09 35.9 7.8 5.1e-09 35.9 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ53508.1 - 9.9e-09 34.9 11.0 9.9e-09 34.9 11.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ53508.1 - 2e-08 34.5 12.5 2e-08 34.5 12.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXZ53508.1 - 1e-07 32.0 10.0 2.5e-07 30.7 10.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXZ53508.1 - 2.8e-07 30.4 10.2 6.8e-07 29.2 10.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXZ53508.1 - 3.5e-05 23.6 10.3 8.2e-05 22.4 10.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXZ53508.1 - 0.00016 21.5 8.7 0.00038 20.4 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KXZ53508.1 - 0.00073 19.3 6.7 0.0016 18.2 6.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KXZ53508.1 - 0.0013 19.0 10.1 0.0037 17.5 10.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXZ53508.1 - 0.0082 15.9 5.4 0.019 14.7 5.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger ResIII PF04851.15 KXZ53508.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_6 PF14835.6 KXZ53508.1 - 0.013 15.4 4.6 0.043 13.7 4.6 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 KXZ53508.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-ANAPC11 PF12861.7 KXZ53508.1 - 0.076 13.1 5.8 0.044 13.8 3.5 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 KXZ53508.1 - 0.61 10.1 3.9 1.5 8.9 3.9 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 KXZ53508.1 - 0.73 9.7 8.5 1.8 8.5 8.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KXZ53508.1 - 0.98 9.6 5.8 2.3 8.4 5.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 KXZ53508.1 - 1.1 8.9 5.5 2.7 7.7 5.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger NIF PF03031.18 KXZ53510.1 - 1.2e-20 73.9 0.0 1.8e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KXZ53510.1 - 1.2e-06 28.8 0.0 2.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXZ53510.1 - 0.00027 20.8 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KXZ53510.1 - 0.085 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain zf-CCCH PF00642.24 KXZ53511.1 - 1.8e-10 40.5 2.6 1.8e-10 40.5 2.6 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXZ53511.1 - 1.4e-06 28.2 4.2 1.4e-06 28.2 4.2 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-RING_5 PF14634.6 KXZ53511.1 - 2.1e-05 24.4 13.1 3.5e-05 23.7 13.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXZ53511.1 - 3.3e-05 23.7 10.0 6.7e-05 22.7 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ53511.1 - 0.00014 22.1 11.5 0.00028 21.2 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXZ53511.1 - 0.00068 19.6 8.6 0.0012 18.8 8.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_4 PF18044.1 KXZ53511.1 - 0.0028 17.4 2.5 0.0028 17.4 2.5 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger zf-C3HC4 PF00097.25 KXZ53511.1 - 0.0028 17.5 13.7 0.0052 16.6 13.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ53511.1 - 0.0049 16.7 12.4 0.01 15.7 12.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KXZ53511.1 - 0.029 14.5 6.4 0.029 14.5 6.4 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KXZ53511.1 - 0.16 11.8 9.8 0.27 11.1 9.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 KXZ53511.1 - 2.7 8.6 6.3 1.1 9.8 2.5 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Fer2 PF00111.27 KXZ53513.1 - 6.3e-06 26.1 0.7 8e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 KXZ53513.1 - 0.005 16.6 2.6 0.0089 15.8 2.6 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Tmemb_185A PF10269.9 KXZ53514.1 - 0.00054 19.7 10.1 0.0017 18.1 10.4 1.7 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein Ank_4 PF13637.6 KXZ53515.1 - 2.9e-07 30.9 0.5 0.1 13.2 0.3 3.5 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ53515.1 - 8.7e-06 26.2 0.7 0.081 13.5 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ53515.1 - 0.0022 18.3 0.0 26 5.8 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KXZ53515.1 - 0.052 13.9 0.3 5.7 7.4 0.0 3.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Band_7 PF01145.25 KXZ53516.1 - 2.6e-31 109.0 0.2 2.6e-31 109.0 0.2 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KXZ53516.1 - 2.8e-25 88.1 1.8 6.5e-25 87.0 1.8 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Pkinase PF00069.25 KXZ53518.1 - 2.2e-29 102.6 0.0 1.2e-26 93.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53518.1 - 8e-22 77.8 0.0 3.8e-19 69.0 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase DUF2397 PF09660.10 KXZ53518.1 - 1.2 8.0 5.1 2 7.2 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) APH PF01636.23 KXZ53518.1 - 6.8 6.5 7.8 0.39 10.6 1.8 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family CRAL_TRIO PF00650.20 KXZ53519.1 - 4.1e-34 117.6 0.0 5.4e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXZ53519.1 - 5.9e-05 23.2 0.0 8.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Vsr PF03852.15 KXZ53519.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr PP2C PF00481.21 KXZ53520.1 - 2.5e-58 197.8 1.8 9.3e-54 182.8 0.6 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KXZ53520.1 - 0.00035 20.6 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KXZ53520.1 - 0.0011 18.6 0.3 0.0055 16.4 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C Oxidored_FMN PF00724.20 KXZ53522.1 - 2.5e-86 290.0 0.0 3e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Methyltransf_16 PF10294.9 KXZ53523.1 - 3.9e-17 62.5 0.0 2.8e-16 59.8 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXZ53523.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KXZ53523.1 - 0.3 10.8 0.0 0.44 10.3 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Mtc PF03820.17 KXZ53524.1 - 0.047 12.7 0.7 0.063 12.3 0.7 1.2 1 0 0 1 1 1 0 Tricarboxylate carrier DUF393 PF04134.12 KXZ53525.1 - 9.6e-16 59.1 0.0 1.8e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF393 CBS PF00571.28 KXZ53525.1 - 8.5e-07 29.3 0.0 0.0015 19.0 0.0 2.8 3 0 0 3 3 3 2 CBS domain RINGv PF12906.7 KXZ53526.1 - 2.8e-07 30.6 9.7 2.8e-07 30.6 9.7 1.9 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 KXZ53526.1 - 3.1 8.2 12.9 1.2 9.5 9.5 2.0 1 1 1 2 2 2 0 Ring finger domain EPL1 PF10513.9 KXZ53527.1 - 0.16 12.3 18.8 0.39 11.1 18.8 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2828 PF11443.8 KXZ53527.1 - 0.2 9.7 17.0 0.31 9.1 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DDHD PF02862.17 KXZ53527.1 - 0.36 11.0 16.8 0.97 9.5 16.8 1.7 1 0 0 1 1 1 0 DDHD domain Gti1_Pac2 PF09729.9 KXZ53527.1 - 1.7 8.7 20.0 3.3 7.8 20.0 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family MMR1 PF08505.10 KXZ53527.1 - 3.1 8.0 28.1 6.1 7.1 28.1 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SUFU_C PF12470.8 KXZ53527.1 - 3.8 7.5 19.1 6.8 6.7 19.1 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain YABBY PF04690.13 KXZ53527.1 - 4.6 7.8 20.4 11 6.5 20.4 1.7 1 0 0 1 1 1 0 YABBY protein RelA_SpoT PF04607.17 KXZ53528.1 - 5.1e-17 62.2 0.0 5e-12 46.1 0.0 2.5 2 0 0 2 2 2 2 Region found in RelA / SpoT proteins HD_4 PF13328.6 KXZ53528.1 - 9.1e-11 41.7 1.8 9.1e-11 41.7 1.8 2.9 2 1 1 3 3 3 1 HD domain EF-hand_1 PF00036.32 KXZ53528.1 - 3.1e-09 35.7 0.0 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KXZ53528.1 - 1.1e-08 34.2 0.7 0.0004 19.7 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXZ53528.1 - 4.8e-08 32.3 0.0 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXZ53528.1 - 6.3e-08 33.0 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ53528.1 - 1.3e-06 28.2 0.0 0.01 15.7 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 KXZ53528.1 - 0.19 11.9 0.0 26 5.1 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KXZ53528.1 - 0.42 10.9 3.7 0.65 10.3 0.0 2.6 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region TFIIA PF03153.13 KXZ53528.1 - 2.3 8.1 10.2 0.17 11.9 3.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ResIII PF04851.15 KXZ53529.1 - 0.0074 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXZ53529.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ndc1_Nup PF09531.10 KXZ53529.1 - 9.4 4.8 8.1 12 4.5 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Helicase_C PF00271.31 KXZ53530.1 - 2.1e-18 66.7 0.0 9.8e-18 64.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXZ53530.1 - 0.00017 20.9 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PHD PF00628.29 KXZ53531.1 - 2.4e-09 36.9 2.1 3.6e-09 36.4 2.1 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXZ53531.1 - 5.3e-06 25.9 0.6 8.2e-06 25.3 0.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 KXZ53531.1 - 0.35 10.5 1.6 0.75 9.4 1.6 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain HALZ PF02183.18 KXZ53532.1 - 0.049 13.9 0.3 0.08 13.2 0.3 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.18 KXZ53532.1 - 0.15 12.4 0.2 0.27 11.6 0.2 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family Ferritin PF00210.24 KXZ53533.1 - 2.9e-32 111.6 1.2 3.6e-32 111.2 1.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain RRM_1 PF00076.22 KXZ53534.1 - 3.5e-34 116.5 0.0 5.7e-16 58.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ53534.1 - 0.0001 22.3 0.1 0.063 13.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KXZ53534.1 - 0.00023 21.2 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 KXZ53534.1 - 0.00041 20.1 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KXZ53534.1 - 0.00089 18.9 0.0 0.0065 16.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-MYND PF01753.18 KXZ53535.1 - 5.7e-08 32.7 10.6 1.1e-07 31.8 10.6 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ53538.1 - 3.8e-09 36.5 13.0 7.1e-09 35.6 13.0 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KXZ53539.1 - 3.8e-09 36.5 12.4 7.1e-09 35.6 12.4 1.4 1 0 0 1 1 1 1 MYND finger DUF2277 PF10041.9 KXZ53539.1 - 0.014 15.8 0.1 0.014 15.8 0.1 3.1 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) zf-MYND PF01753.18 KXZ53543.1 - 8.7e-09 35.3 10.6 1.8e-08 34.4 10.6 1.5 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.25 KXZ53544.1 - 5.6e-66 222.6 0.0 6.6e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53544.1 - 1.9e-27 96.2 0.0 2.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ53544.1 - 0.00035 20.0 0.0 0.003 16.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXZ53544.1 - 0.042 12.6 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Hydrolase_4 PF12146.8 KXZ53545.1 - 5.9e-14 51.9 0.0 2.8e-08 33.3 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ53545.1 - 6.3e-08 32.6 0.2 4.1e-05 23.3 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ53545.1 - 0.00035 21.2 3.8 0.00035 21.2 3.8 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KXZ53545.1 - 0.00078 19.2 0.1 0.0042 16.8 0.0 1.9 1 1 1 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 KXZ53545.1 - 0.003 17.1 0.0 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXZ53545.1 - 0.0035 16.9 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KXZ53545.1 - 0.004 17.0 0.0 0.019 14.8 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 KXZ53545.1 - 0.018 14.0 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 KXZ53545.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 KXZ53545.1 - 0.024 14.0 0.4 2 7.7 0.2 2.3 2 0 0 2 2 2 0 Secretory lipase Peptidase_M50 PF02163.22 KXZ53546.1 - 2e-07 30.5 3.5 0.00012 21.4 0.1 3.0 2 1 0 3 3 3 2 Peptidase family M50 Fic PF02661.18 KXZ53548.1 - 5.2e-14 52.9 0.0 9.5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family O-FucT PF10250.9 KXZ53549.1 - 5.2e-09 36.3 0.1 8.9e-09 35.5 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3707 PF12499.8 KXZ53550.1 - 3.1e-20 73.2 2.4 3.1e-20 73.2 2.4 2.2 3 0 0 3 3 3 1 Pherophorin DUF3707 PF12499.8 KXZ53551.1 - 1.9e-52 177.6 26.0 8.9e-32 110.6 6.4 3.0 3 0 0 3 3 3 2 Pherophorin DUF3707 PF12499.8 KXZ53552.1 - 2.8e-32 112.3 21.0 1e-16 61.8 9.0 2.1 2 0 0 2 2 2 2 Pherophorin DUF3707 PF12499.8 KXZ53554.1 - 1.5e-14 54.8 3.4 1.6e-14 54.6 3.4 1.0 1 0 0 1 1 1 1 Pherophorin GTP_EFTU PF00009.27 KXZ53556.1 - 4.2e-26 91.7 1.8 5.9e-26 91.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain tRNA_bind PF01588.20 KXZ53556.1 - 6e-15 55.1 0.0 1.8e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Putative tRNA binding domain GTP_EFTU_D2 PF03144.25 KXZ53556.1 - 2.3e-06 27.9 4.3 4.4e-06 27.0 0.3 3.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ53556.1 - 9.1e-06 25.7 0.0 7e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KXZ53556.1 - 0.034 14.4 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 KXZ53557.1 - 4.1e-24 84.4 23.5 9.8e-05 23.1 0.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ53557.1 - 0.0016 18.7 0.0 0.26 11.6 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Bromodomain PF00439.25 KXZ53558.1 - 4.3e-09 36.3 0.0 7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain GSHPx PF00255.19 KXZ53559.1 - 6.5e-19 67.5 0.0 9.1e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Lipase_3 PF01764.25 KXZ53560.1 - 0.0042 17.0 0.1 0.0086 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 KXZ53560.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 KXZ53560.1 - 0.19 11.8 0.1 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 Thioesterase domain UPF0227 PF05728.12 KXZ53560.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) CSD PF00313.22 KXZ53561.1 - 4.4e-10 39.3 0.0 9.3e-10 38.2 0.0 1.6 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain Presenilin PF01080.17 KXZ53562.1 - 1.4e-70 238.1 19.4 5.5e-39 134.1 0.0 3.0 2 1 0 2 2 2 2 Presenilin DUF3431 PF11913.8 KXZ53563.1 - 3.2e-09 36.9 0.0 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) APH PF01636.23 KXZ53565.1 - 0.048 13.6 0.1 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family APH PF01636.23 KXZ53566.1 - 0.00093 19.2 0.5 0.22 11.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ53566.1 - 0.033 13.0 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXZ53566.1 - 0.051 12.9 0.0 0.07 12.5 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ53566.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain IMS PF00817.20 KXZ53568.1 - 1.1e-44 152.1 0.0 2.4e-44 151.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXZ53568.1 - 4.7e-13 49.9 0.3 1.9e-12 47.9 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXZ53568.1 - 0.023 15.0 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif CLZ PF16526.5 KXZ53568.1 - 0.054 13.9 0.6 0.17 12.2 0.6 1.9 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels tRNA-synt_2d PF01409.20 KXZ53570.1 - 4e-47 160.8 0.0 8.5e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KXZ53570.1 - 6.8e-26 90.5 0.0 2.2e-25 88.9 0.0 2.0 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GED PF02212.18 KXZ53570.1 - 1.6e-11 44.1 0.6 4.2e-11 42.9 0.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.20 KXZ53570.1 - 2.8e-09 36.6 0.1 5.1e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Dynamin central region PH PF00169.29 KXZ53570.1 - 1.3e-08 35.3 0.0 3.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KXZ53570.1 - 0.068 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain OTCace_N PF02729.21 KXZ53571.1 - 1.4e-39 135.5 0.0 2.2e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KXZ53571.1 - 3.2e-33 115.0 0.0 4.5e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain HATPase_c PF02518.26 KXZ53572.1 - 1.1e-18 67.7 0.0 2.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KXZ53572.1 - 7.5e-17 61.5 0.0 1.4e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain Response_reg PF00072.24 KXZ53572.1 - 4.7e-10 39.6 0.1 1.3e-08 34.9 0.0 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXZ53572.1 - 2.9e-09 36.8 0.2 1.1e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KXZ53572.1 - 0.00034 20.8 1.0 0.0026 18.0 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 KXZ53572.1 - 0.029 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold NrsF PF06532.11 KXZ53573.1 - 0.0016 18.2 1.8 0.0023 17.7 1.8 1.2 1 0 0 1 1 1 1 Negative regulator of sigma F Gag_p30 PF02093.16 KXZ53573.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Gag P30 core shell protein Guanylate_cyc PF00211.20 KXZ53574.1 - 2.2e-57 193.6 0.0 3.4e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Beta-Casp PF10996.8 KXZ53575.1 - 6e-19 68.4 0.0 4.7e-18 65.5 0.0 2.1 1 1 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KXZ53575.1 - 1e-15 57.4 0.0 2.9e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 KXZ53575.1 - 1e-10 41.3 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KXZ53575.1 - 2.2e-08 34.4 3.1 2.2e-08 34.4 3.1 3.2 3 1 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXZ53575.1 - 3.9e-06 26.5 0.4 2.7e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Aldolase_II PF00596.21 KXZ53577.1 - 0.0016 18.4 0.0 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Homeodomain PF00046.29 KXZ53577.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain Pkinase_Tyr PF07714.17 KXZ53579.1 - 1.5e-26 93.2 0.0 5.7e-12 45.5 0.0 3.4 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ53579.1 - 5.1e-24 85.0 0.0 1.6e-10 40.8 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ53579.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FtsJ PF01728.19 KXZ53580.1 - 4.8e-09 36.6 0.0 7.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ribosomal_S4e PF00900.20 KXZ53581.1 - 1.1e-38 131.0 1.1 1.7e-37 127.2 0.1 2.4 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KXZ53581.1 - 1.3e-24 85.5 0.1 3.2e-24 84.3 0.1 1.7 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KXZ53581.1 - 3.9e-21 74.9 6.0 7.8e-21 73.9 6.0 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KXZ53581.1 - 4.3e-07 29.5 0.0 9.1e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KXZ53581.1 - 9.3e-07 28.6 5.1 9.7e-07 28.5 2.4 2.5 2 0 0 2 2 2 1 KOW motif dCache_2 PF08269.11 KXZ53581.1 - 0.0049 16.1 0.0 0.019 14.2 0.0 1.7 1 1 1 2 2 2 1 Cache domain Sipho_tail PF05709.11 KXZ53581.1 - 0.073 12.5 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Phage tail protein LON_substr_bdg PF02190.16 KXZ53581.1 - 0.098 12.5 0.4 12 5.7 0.1 2.1 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain FAD_binding_3 PF01494.19 KXZ53582.1 - 3.3e-12 46.3 0.5 5e-12 45.7 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain p450 PF00067.22 KXZ53583.1 - 1.4e-65 221.9 0.0 1e-55 189.3 0.0 3.5 1 1 1 2 2 2 2 Cytochrome P450 TPPII_N PF12583.8 KXZ53583.1 - 0.074 13.6 1.5 0.17 12.5 1.5 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Lectin_C PF00059.21 KXZ53584.1 - 0.00047 20.9 0.9 0.055 14.2 0.3 2.2 1 1 1 2 2 2 2 Lectin C-type domain UL45 PF05473.12 KXZ53584.1 - 0.00055 19.6 0.3 0.0011 18.6 0.0 1.6 1 1 1 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like XdhC_CoxI PF02625.16 KXZ53584.1 - 0.22 11.7 0.3 0.35 11.1 0.3 1.2 1 0 0 1 1 1 0 XdhC and CoxI family FAD_binding_4 PF01565.23 KXZ53585.1 - 3e-26 91.8 0.1 3e-26 91.8 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain DUF4558 PF15104.6 KXZ53587.1 - 1.7e-10 40.8 1.1 2.2e-10 40.5 1.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) Ribosomal_L9_C PF03948.14 KXZ53588.1 - 0.005 17.3 0.0 0.0064 16.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain MBG_2 PF18676.1 KXZ53590.1 - 0.1 13.2 0.5 0.59 10.8 0.0 2.4 3 0 0 3 3 3 0 MBG domain (YGX type) Kelch_5 PF13854.6 KXZ53591.1 - 6.4e-06 26.0 6.3 0.79 9.8 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KXZ53591.1 - 0.00028 20.8 0.0 0.00028 20.8 0.0 3.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ53591.1 - 0.023 15.0 0.8 1.1 9.7 0.0 3.8 3 1 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 KXZ53591.1 - 0.045 13.3 0.3 0.25 11.0 0.0 2.5 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 KXZ53591.1 - 0.062 13.3 3.5 1.9 8.6 0.0 3.7 4 0 0 4 4 4 0 Kelch motif YL1 PF05764.13 KXZ53592.1 - 2.6e-22 80.1 39.6 2.6e-22 80.1 39.6 2.3 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KXZ53592.1 - 6e-10 38.7 0.0 9.2e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Cmyb_C PF09316.10 KXZ53592.1 - 0.046 13.4 4.6 0.066 12.9 0.1 2.8 2 1 0 2 2 2 0 C-myb, C-terminal Cnd2 PF05786.14 KXZ53592.1 - 5.6 5.5 20.5 0.64 8.6 3.2 2.2 2 0 0 2 2 2 0 Condensin complex subunit 2 SDA1 PF05285.12 KXZ53592.1 - 7.9 5.8 33.7 20 4.5 33.7 1.6 1 1 0 1 1 1 0 SDA1 Synaptobrevin PF00957.21 KXZ53593.1 - 6.7e-15 54.6 0.5 1.1e-14 54.0 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXZ53593.1 - 6.2e-10 39.0 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 KXZ53593.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Peptidase_M20 PF01546.28 KXZ53594.1 - 1.1e-23 84.0 3.9 5.3e-22 78.5 3.9 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXZ53594.1 - 7e-05 22.7 0.3 7e-05 22.7 0.3 2.0 2 1 0 2 2 2 1 Peptidase dimerisation domain HSP70 PF00012.20 KXZ53595.1 - 8.8e-260 863.0 5.3 9.9e-260 862.9 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ53595.1 - 1.4e-15 57.0 0.0 2.2e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXZ53595.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4795 PF16043.5 KXZ53595.1 - 0.17 11.5 14.4 0.57 9.8 14.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) MutS_III PF05192.18 KXZ53595.1 - 1.3 9.2 3.7 34 4.6 0.0 2.4 2 1 1 3 3 3 0 MutS domain III Uds1 PF15456.6 KXZ53595.1 - 3.4 7.8 9.7 0.43 10.7 4.4 2.0 2 0 0 2 2 2 0 Up-regulated During Septation TPR_19 PF14559.6 KXZ53596.1 - 0.062 13.8 2.9 11 6.6 0.6 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Phage_TAC_11 PF11836.8 KXZ53596.1 - 0.54 10.4 4.9 1 9.5 3.4 2.0 1 1 0 2 2 2 0 Phage tail tube protein, GTA-gp10 RPN2_C PF18004.1 KXZ53597.1 - 1.8e-33 115.7 0.1 2.7e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KXZ53597.1 - 9.4e-19 66.8 23.2 1.5e-06 28.3 0.4 6.5 6 0 0 6 6 6 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXZ53597.1 - 8.3e-11 42.1 1.3 0.00019 21.8 0.0 3.3 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.22 KXZ53597.1 - 0.0067 16.6 0.0 0.29 11.5 0.1 3.4 3 0 0 3 3 3 1 HEAT repeat ATXN-1_C PF12547.8 KXZ53597.1 - 0.12 12.7 0.3 0.34 11.3 0.3 1.7 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator FancD2 PF14631.6 KXZ53599.1 - 1.3e-10 39.4 0.0 2.5e-08 31.9 0.0 2.8 3 0 0 3 3 3 2 Fanconi anaemia protein FancD2 nuclease FancD2 PF14631.6 KXZ53600.1 - 0.025 12.0 0.0 0.027 11.9 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RWP-RK PF02042.15 KXZ53602.1 - 7.5e-11 41.8 0.0 1.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain Cyclin_C PF02984.19 KXZ53602.1 - 0.068 13.3 4.4 0.18 11.9 4.4 1.7 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF1287 PF06940.11 KXZ53602.1 - 0.089 12.4 0.4 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1287) Ofd1_CTDD PF10637.9 KXZ53602.1 - 3.8 6.8 6.7 6.4 6.0 6.7 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term 2-Hacid_dh_C PF02826.19 KXZ53603.1 - 4.2e-57 192.4 0.0 9.6e-57 191.2 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXZ53603.1 - 7e-36 122.8 1.0 1.1e-35 122.2 0.5 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KXZ53603.1 - 3.7e-05 23.8 0.1 0.00014 21.9 0.0 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KXZ53603.1 - 0.00019 21.0 0.1 0.00042 19.9 0.1 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KXZ53603.1 - 0.0036 17.5 1.5 0.022 14.9 0.1 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KXZ53603.1 - 0.0038 17.7 0.4 0.026 15.0 0.0 2.2 2 0 0 2 2 2 1 XdhC Rossmann domain Endonuclease_5 PF04493.14 KXZ53604.1 - 1.8e-13 50.6 0.0 5.5e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Endonuclease V Peripla_BP_6 PF13458.6 KXZ53604.1 - 0.064 12.9 0.9 5.7 6.5 0.7 2.1 1 1 1 2 2 2 0 Periplasmic binding protein Ribosomal_L35p PF01632.19 KXZ53605.1 - 0.0012 19.3 1.5 0.0019 18.6 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 GATase PF00117.28 KXZ53606.1 - 3.4e-07 30.2 0.0 0.0067 16.2 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I BLOC1_2 PF10046.9 KXZ53606.1 - 2e-06 28.0 0.0 3.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GATase_3 PF07685.14 KXZ53606.1 - 0.03 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DnaJ PF00226.31 KXZ53607.1 - 0.065 13.4 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 DnaJ domain LRR_4 PF12799.7 KXZ53608.1 - 5.3e-05 23.5 0.5 4.5 7.8 0.0 5.2 7 1 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ53608.1 - 0.0009 19.1 3.4 10 6.5 0.0 5.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 KXZ53608.1 - 0.0036 17.0 5.4 0.35 10.7 0.0 5.1 7 1 0 7 7 7 1 Leucine rich repeat QH-AmDH_gamma PF08992.11 KXZ53608.1 - 0.19 11.7 0.6 0.44 10.6 0.1 1.9 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, gamma subunit TPR_8 PF13181.6 KXZ53609.1 - 1.1e-05 25.2 1.8 0.52 10.7 0.8 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ53609.1 - 4.1e-05 24.1 6.7 0.00057 20.5 0.7 10.8 8 3 3 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ53609.1 - 0.00031 21.2 36.7 0.12 12.9 0.3 6.3 4 2 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ53609.1 - 0.00045 19.8 0.1 0.0061 16.2 0.0 2.9 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 KXZ53609.1 - 0.00087 19.2 19.8 0.093 12.9 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ53609.1 - 0.0053 16.0 0.6 0.0053 16.0 0.6 3.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ53609.1 - 0.17 11.8 9.8 2.4 8.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ53609.1 - 5.7 7.6 6.6 47 4.7 0.0 5.6 7 2 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ53609.1 - 8.7 6.6 8.5 17 5.7 0.8 4.1 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 2Fe-2S_thioredx PF01257.19 KXZ53611.1 - 0.0045 16.8 0.0 0.005 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin PRA1 PF03208.19 KXZ53614.1 - 2.4e-32 111.5 5.2 3.3e-32 111.1 5.2 1.1 1 0 0 1 1 1 1 PRA1 family protein AgrB PF04647.15 KXZ53614.1 - 0.085 12.2 4.8 0.12 11.6 4.8 1.3 1 0 0 1 1 1 0 Accessory gene regulator B Colicin_im PF03857.13 KXZ53614.1 - 0.12 12.3 4.2 0.092 12.7 2.3 1.7 1 1 1 2 2 2 0 Colicin immunity protein FtsX PF02687.21 KXZ53614.1 - 1.4 9.5 10.2 14 6.2 0.1 2.1 1 1 1 2 2 2 0 FtsX-like permease family DUF2070 PF09843.9 KXZ53614.1 - 5.2 5.2 9.8 6.3 5.0 9.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) mTERF PF02536.14 KXZ53616.1 - 0.0028 16.6 0.0 0.0099 14.8 0.0 1.9 2 0 0 2 2 2 1 mTERF HTH_25 PF13413.6 KXZ53616.1 - 0.012 15.4 1.5 0.017 15.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain RRM_1 PF00076.22 KXZ53617.1 - 5.2e-10 39.0 0.0 0.063 13.1 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IBR PF01485.21 KXZ53617.1 - 1.3e-08 34.9 10.4 1.3e-08 34.9 10.4 3.6 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain YhfH PF14149.6 KXZ53617.1 - 0.0017 18.3 4.7 0.0017 18.3 4.7 3.9 4 0 0 4 4 4 1 YhfH-like protein zf-C3HC4 PF00097.25 KXZ53617.1 - 0.0056 16.5 12.2 0.0056 16.5 12.2 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.11 KXZ53617.1 - 0.63 10.0 9.2 1.7 8.6 9.2 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_2 PF13639.6 KXZ53617.1 - 8 6.9 31.4 0.21 12.0 10.4 4.0 2 2 1 3 3 3 0 Ring finger domain Aldo_ket_red PF00248.21 KXZ53619.1 - 9.2e-58 195.8 0.0 2.4e-49 168.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF2334 PF10096.9 KXZ53619.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) LPD22 PF18834.1 KXZ53619.1 - 0.12 12.7 0.0 0.89 9.8 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 DUF4202 PF13875.6 KXZ53620.1 - 2.5e-60 203.6 0.0 3.2e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Ribosomal_60s PF00428.19 KXZ53620.1 - 0.0064 17.0 3.1 0.016 15.8 3.1 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ank_4 PF13637.6 KXZ53621.1 - 4.4e-05 23.9 0.3 0.00012 22.6 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 KXZ53621.1 - 8.3e-05 22.4 3.4 0.00016 21.5 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_3 PF13606.6 KXZ53621.1 - 0.00024 21.3 2.7 0.08 13.5 0.3 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXZ53621.1 - 0.001 19.6 0.7 0.0039 17.8 1.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C3HC4 PF00097.25 KXZ53621.1 - 0.0021 17.9 3.0 0.0036 17.2 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ53621.1 - 0.0033 17.7 4.0 0.0066 16.8 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KXZ53621.1 - 0.012 15.4 1.4 0.028 14.2 1.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXZ53621.1 - 0.03 14.5 5.0 0.054 13.7 5.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXZ53621.1 - 0.035 14.0 3.6 0.079 12.8 3.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXZ53621.1 - 0.061 13.3 4.5 0.12 12.4 4.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Ank_5 PF13857.6 KXZ53621.1 - 0.074 13.4 2.3 13 6.3 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ53621.1 - 0.67 10.5 6.5 1.5 9.4 0.6 3.2 3 0 0 3 3 3 0 Ankyrin repeat zf-C3HC4_2 PF13923.6 KXZ53621.1 - 5.4 6.9 6.1 10 6.1 6.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 KXZ53622.1 - 2.7e-26 92.0 0.6 2.7e-13 50.3 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53622.1 - 1.4e-22 79.7 2.8 1.4e-09 38.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53622.1 - 4.3e-21 72.8 1.5 9.1e-07 28.7 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXZ53622.1 - 1.5e-17 63.4 5.3 5.3e-07 29.8 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ53622.1 - 1.1e-14 54.1 3.8 5.1e-05 23.5 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat DUF883 PF05957.13 KXZ53622.1 - 0.18 12.4 2.2 1.3 9.7 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) UEV PF05743.13 KXZ53623.1 - 4.2e-32 110.5 0.3 7e-32 109.8 0.3 1.3 1 0 0 1 1 1 1 UEV domain Bac_globin PF01152.21 KXZ53623.1 - 1.4e-24 86.6 0.6 1.6e-07 31.5 0.1 3.5 3 0 0 3 3 3 3 Bacterial-like globin Vps23_core PF09454.10 KXZ53623.1 - 5.8e-19 67.8 2.9 2.1e-18 66.0 0.1 3.0 2 0 0 2 2 2 1 Vps23 core domain Protoglobin PF11563.8 KXZ53623.1 - 0.00027 20.9 0.8 0.41 10.5 0.0 3.0 3 0 0 3 3 3 2 Protoglobin UQ_con PF00179.26 KXZ53623.1 - 0.0027 17.4 0.2 0.0051 16.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF737 PF05300.11 KXZ53623.1 - 0.032 14.6 0.0 0.032 14.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF737) CRIC_ras_sig PF10534.9 KXZ53623.1 - 0.07 13.3 1.0 0.22 11.7 0.5 2.1 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras DUF3584 PF12128.8 KXZ53623.1 - 3 5.3 10.1 0.14 9.6 4.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Mad3_BUB1_I PF08311.12 KXZ53625.1 - 1e-30 106.3 0.2 1.4e-30 105.8 0.2 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 KXZ53625.1 - 1.3e-07 31.7 0.0 2.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase PF00069.25 KXZ53626.1 - 8.3e-20 71.2 0.0 3.1e-16 59.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53626.1 - 8.9e-15 54.7 0.0 1.5e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_14 PF13428.6 KXZ53627.1 - 0.095 13.6 4.9 1.8 9.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PSRP-3_Ycf65 PF04839.13 KXZ53628.1 - 6.5e-27 93.5 3.9 1.2e-26 92.6 3.9 1.5 1 0 0 1 1 1 1 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) FF PF01846.19 KXZ53629.1 - 2.6e-46 155.6 12.9 1.2e-14 54.2 0.0 5.6 5 0 0 5 5 5 4 FF domain WW PF00397.26 KXZ53629.1 - 6.3e-21 74.2 16.4 1.6e-10 40.8 4.1 2.8 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KXZ53629.1 - 0.00019 22.0 8.2 1.1 10.0 0.3 3.6 2 1 1 3 3 3 3 p190-A and -B Rho GAPs FF domain Cpn60_TCP1 PF00118.24 KXZ53629.1 - 0.029 13.0 0.1 0.045 12.4 0.1 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Glyco_hyd_101C PF17451.2 KXZ53629.1 - 1.6 9.0 6.4 4.5 7.6 0.9 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain T2SSF PF00482.23 KXZ53629.1 - 3.4 7.6 5.4 0.54 10.2 0.2 2.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Ebp2 PF05890.12 KXZ53630.1 - 6.7e-40 137.3 30.1 7.9e-40 137.1 30.1 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF1077 PF06417.12 KXZ53631.1 - 4.9e-27 94.3 0.6 6e-27 94.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF667 PF05018.13 KXZ53633.1 - 1.8e-89 298.3 0.5 2.1e-89 298.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) CCT PF06203.14 KXZ53634.1 - 5.7e-17 61.5 6.8 9.2e-17 60.8 6.8 1.3 1 0 0 1 1 1 1 CCT motif NAD_binding_8 PF13450.6 KXZ53634.1 - 0.15 12.3 0.0 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain WD40 PF00400.32 KXZ53635.1 - 1.2e-41 139.9 10.0 3.3e-05 24.6 0.3 12.6 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ53635.1 - 1.1e-26 92.9 0.0 0.02 15.2 0.0 10.5 7 3 4 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXZ53635.1 - 0.0039 17.1 0.0 2.9 7.9 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat NACHT PF05729.12 KXZ53635.1 - 0.0066 16.4 8.8 0.021 14.7 4.1 2.7 2 1 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 KXZ53635.1 - 0.0092 15.0 2.1 31 3.4 0.0 5.7 6 2 1 7 7 7 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1205 PF06722.12 KXZ53635.1 - 0.06 13.4 0.0 6.6 6.9 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) VID27 PF08553.10 KXZ53635.1 - 0.073 12.1 0.0 0.58 9.2 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PQQ_3 PF13570.6 KXZ53635.1 - 1.1 9.9 10.6 6.6 7.4 0.2 5.5 6 0 0 6 6 6 0 PQQ-like domain AOX PF01786.17 KXZ53636.1 - 2.3e-23 82.9 0.3 3.1e-23 82.5 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-C4H2 PF10146.9 KXZ53637.1 - 0.0021 18.4 7.3 0.003 17.9 7.3 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein DUF812 PF05667.11 KXZ53637.1 - 0.0085 15.0 9.0 0.01 14.7 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Phage_GP20 PF06810.11 KXZ53637.1 - 0.016 15.0 4.9 0.25 11.1 0.4 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 KXZ53637.1 - 0.059 13.5 3.5 0.11 12.7 3.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADPrib_exo_Tox PF03496.14 KXZ53637.1 - 0.071 12.4 0.1 0.098 12.0 0.1 1.2 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme DUF111 PF01969.17 KXZ53637.1 - 0.12 11.4 3.9 0.17 10.9 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF111 Peptidase_S46 PF10459.9 KXZ53637.1 - 0.13 10.9 6.8 0.14 10.7 6.8 1.0 1 0 0 1 1 1 0 Peptidase S46 Spc7 PF08317.11 KXZ53637.1 - 0.29 10.0 14.0 0.4 9.5 14.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FAM76 PF16046.5 KXZ53637.1 - 0.32 10.3 3.8 0.48 9.7 3.8 1.4 1 0 0 1 1 1 0 FAM76 protein XhlA PF10779.9 KXZ53637.1 - 0.41 10.9 4.2 0.36 11.1 2.3 1.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF1690 PF07956.11 KXZ53637.1 - 0.43 11.0 14.8 0.76 10.2 14.8 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) AAA_13 PF13166.6 KXZ53637.1 - 0.59 8.7 7.4 0.77 8.3 7.4 1.1 1 0 0 1 1 1 0 AAA domain Apt1 PF10351.9 KXZ53637.1 - 0.75 8.6 8.4 1.1 8.0 8.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SurA_N_2 PF13623.6 KXZ53637.1 - 0.75 9.7 3.2 1.2 9.0 1.4 2.1 1 1 1 2 2 2 0 SurA N-terminal domain DUF5082 PF16888.5 KXZ53637.1 - 1 9.6 10.4 0.24 11.7 4.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FapA PF03961.13 KXZ53637.1 - 1.1 7.8 3.2 1.4 7.4 3.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF16 PF01519.16 KXZ53637.1 - 1.2 9.6 4.3 2.9 8.4 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 KXZ53637.1 - 1.2 8.6 12.3 1.8 8.1 12.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KXZ53637.1 - 2.4 6.0 6.9 3.1 5.6 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KXZ53637.1 - 2.6 8.1 11.6 4.3 7.4 11.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 KXZ53637.1 - 3.5 7.9 16.3 0.076 13.4 6.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 KXZ53637.1 - 4.2 7.8 19.6 33 4.9 19.7 2.0 1 1 1 2 2 2 0 Fez1 TFIIA PF03153.13 KXZ53637.1 - 4.7 7.1 8.7 6 6.8 8.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMPIT PF07851.13 KXZ53637.1 - 5.8 6.1 7.3 8 5.6 7.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 KXZ53637.1 - 9.6 5.5 15.3 15 4.8 14.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) B12-binding_2 PF02607.17 KXZ53638.1 - 4.9e-15 55.7 0.0 1.2e-14 54.4 0.0 1.6 2 0 0 2 2 2 1 B12 binding domain Met_synt_B12 PF02965.17 KXZ53639.1 - 8.4e-120 399.3 0.0 1.2e-119 398.8 0.0 1.2 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding PF02310.19 KXZ53639.1 - 3.1e-19 69.2 0.9 5.1e-19 68.5 0.1 1.7 2 0 0 2 2 2 1 B12 binding domain PALP PF00291.25 KXZ53640.1 - 2.9e-51 174.6 0.2 3.9e-51 174.2 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Exo_endo_phos PF03372.23 KXZ53641.1 - 7.8e-06 25.6 0.1 0.0011 18.5 0.1 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA-synt_1 PF00133.22 KXZ53642.1 - 2.1e-213 709.9 0.0 2.5e-212 706.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXZ53642.1 - 8e-38 129.8 0.0 1.5e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXZ53642.1 - 3.8e-25 88.5 0.0 6.5e-08 31.7 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KXZ53642.1 - 1.3e-14 54.2 2.6 2.8e-14 53.1 2.6 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 KXZ53642.1 - 1.3e-08 34.5 0.0 6e-06 25.9 0.0 2.3 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KXZ53642.1 - 2.3e-05 23.9 0.0 0.0025 17.2 0.0 2.6 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KXZ53642.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Rhodanese PF00581.20 KXZ53644.1 - 1.7e-12 47.8 0.0 2.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PseudoU_synth_1 PF01416.20 KXZ53644.1 - 0.056 13.9 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 tRNA pseudouridine synthase DUF913 PF06025.12 KXZ53646.1 - 0.085 11.8 1.6 0.13 11.3 1.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 KXZ53646.1 - 0.44 10.3 14.1 0.58 9.9 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KXZ53646.1 - 3.1 6.0 8.1 3.4 5.9 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein UL45 PF05473.12 KXZ53647.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 KXZ53648.1 - 0.033 14.9 0.4 0.072 13.8 0.3 1.6 1 1 1 2 2 2 0 Lectin C-type domain Lectin_C PF00059.21 KXZ53649.1 - 0.00079 20.1 0.2 0.24 12.2 0.1 2.1 1 1 1 2 2 2 2 Lectin C-type domain UL45 PF05473.12 KXZ53649.1 - 0.035 13.8 0.0 0.044 13.4 0.0 1.0 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like MBOAT_2 PF13813.6 KXZ53650.1 - 1.6e-10 41.1 0.2 1.5e-05 25.2 0.1 2.2 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family MBOAT PF03062.19 KXZ53650.1 - 0.029 13.7 0.2 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXZ53651.1 - 1.6e-11 44.3 0.0 2.8e-05 24.3 0.1 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family TAF6_C PF07571.13 KXZ53652.1 - 3.4e-29 101.0 0.1 3.2e-28 97.9 0.0 2.3 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain NAD_binding_10 PF13460.6 KXZ53653.1 - 5.3e-36 124.2 0.0 6.3e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXZ53653.1 - 3.3e-14 53.0 0.0 4.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KXZ53653.1 - 5.5e-07 28.9 0.0 7.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXZ53653.1 - 3.7e-05 23.3 0.0 7.7e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 KXZ53653.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 HIM1 Polysacc_synt_2 PF02719.15 KXZ53653.1 - 0.066 12.3 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PKcGMP_CC PF16808.5 KXZ53654.1 - 0.015 15.1 0.4 0.015 15.1 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 KXZ53654.1 - 0.072 13.4 5.1 0.094 13.1 0.2 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Sec2p PF06428.11 KXZ53654.1 - 0.52 10.3 5.7 3.3 7.7 0.6 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p WD40 PF00400.32 KXZ53655.1 - 8.5e-18 64.4 8.0 1.1e-05 26.1 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF4710 PF15828.5 KXZ53655.1 - 0.03 14.4 0.7 0.03 14.4 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) MBOAT_2 PF13813.6 KXZ53656.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 KXZ53657.1 - 5.9e-10 39.3 0.2 1.1e-05 25.6 0.0 2.3 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family WD40 PF00400.32 KXZ53658.1 - 2.2e-09 37.8 1.0 0.0023 18.7 0.5 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Med22 PF06179.12 KXZ53659.1 - 0.0043 17.2 2.9 0.013 15.7 2.9 1.8 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PLAC9 PF15205.6 KXZ53659.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 Spc7 PF08317.11 KXZ53659.1 - 0.018 13.9 4.0 0.022 13.6 4.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein tRNA-synt_His PF13393.6 KXZ53659.1 - 0.051 12.8 2.1 0.066 12.5 2.1 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase PTR PF12789.7 KXZ53659.1 - 0.13 12.3 2.7 0.3 11.2 2.0 2.0 1 1 1 2 2 2 0 Phage tail repeat like FUSC PF04632.12 KXZ53659.1 - 0.19 10.2 3.6 0.21 10.1 3.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family COX7C PF02935.16 KXZ53660.1 - 0.0014 18.8 4.9 0.0024 18.1 4.9 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Helicase_C PF00271.31 KXZ53661.1 - 5.2e-23 81.5 0.0 8.6e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ53661.1 - 9.5e-20 71.1 0.0 2.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HAD PF12710.7 KXZ53661.1 - 0.13 12.7 5.0 0.075 13.4 1.6 2.4 2 2 1 3 3 3 0 haloacid dehalogenase-like hydrolase Cupin_2 PF07883.11 KXZ53662.1 - 1.7e-05 24.4 0.4 3.8e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_8 PF13621.6 KXZ53662.1 - 0.022 14.5 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain Ribosomal_L2_C PF03947.18 KXZ53664.1 - 5.7e-43 146.1 2.4 6.5e-43 145.9 0.3 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXZ53664.1 - 3e-18 65.5 0.1 1.1e-17 63.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain RRM_1 PF00076.22 KXZ53665.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M11 PF05548.11 KXZ53666.1 - 4.6e-73 246.1 3.1 9.1e-71 238.6 3.1 2.3 1 1 0 1 1 1 1 Gametolysin peptidase M11 Keratin_B2_2 PF13885.6 KXZ53666.1 - 3.6e-05 23.6 6.9 0.086 12.8 0.8 3.1 2 1 0 2 2 2 2 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 KXZ53666.1 - 0.059 13.4 22.7 0.026 14.5 3.3 3.1 2 1 1 3 3 3 0 Keratin, high sulfur B2 protein Reprolysin_5 PF13688.6 KXZ53666.1 - 0.06 13.5 1.4 0.13 12.4 1.4 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXZ53666.1 - 0.1 13.1 0.5 0.25 11.9 0.5 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXZ53666.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Matrixin Cwf_Cwc_15 PF04889.12 KXZ53667.1 - 0.087 12.5 5.7 0.1 12.4 5.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HA2 PF04408.23 KXZ53668.1 - 6.4e-17 61.8 0.0 1.5e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXZ53668.1 - 4e-14 52.9 0.0 6.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXZ53668.1 - 1e-11 45.0 0.2 7.5e-10 39.0 0.2 2.4 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KXZ53669.1 - 2.7e-05 24.5 0.1 0.00022 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KXZ53669.1 - 0.0001 22.1 0.1 0.00034 20.4 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KXZ53669.1 - 0.00033 20.4 0.0 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXZ53669.1 - 0.021 15.1 0.0 0.07 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXZ53669.1 - 0.048 12.7 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KXZ53669.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain PWI PF01480.17 KXZ53669.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 PWI domain SnoaL_2 PF12680.7 KXZ53671.1 - 3.4e-06 27.6 1.2 8.1e-06 26.4 0.3 2.0 2 1 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 KXZ53671.1 - 0.032 14.0 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Herpes_capsid PF06112.11 KXZ53671.1 - 5.8 7.0 7.9 11 6.1 7.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Aldose_epim PF01263.20 KXZ53672.1 - 4.6e-43 147.6 0.0 5.1e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pup_ligase PF03136.15 KXZ53673.1 - 0.2 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Pup-ligase protein Wtap PF17098.5 KXZ53674.1 - 7.3e-33 113.7 16.9 7.3e-33 113.7 16.9 1.8 1 1 1 2 2 2 1 WTAP/Mum2p family DUF4530 PF15039.6 KXZ53674.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4530) Cnn_1N PF07989.11 KXZ53674.1 - 0.18 12.0 9.9 2.4 8.4 0.0 4.0 3 1 0 4 4 4 0 Centrosomin N-terminal motif 1 FapA PF03961.13 KXZ53674.1 - 0.35 9.4 6.2 0.3 9.6 1.3 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A DUF4618 PF15397.6 KXZ53674.1 - 0.6 9.5 9.3 0.09 12.2 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Tektin PF03148.14 KXZ53674.1 - 0.6 8.8 15.7 0.12 11.1 5.6 2.4 2 1 0 2 2 2 0 Tektin family DUF4201 PF13870.6 KXZ53674.1 - 0.67 9.7 11.2 4.4 7.0 4.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 KXZ53674.1 - 0.83 9.0 18.1 8 5.7 16.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXZ53674.1 - 1.1 8.3 9.8 1.2 8.2 1.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP-synt_D PF01813.17 KXZ53674.1 - 1.4 8.7 15.1 2.5 7.9 15.1 1.5 1 1 0 1 1 1 0 ATP synthase subunit D GAS PF13851.6 KXZ53674.1 - 1.5 8.1 19.8 5.9 6.2 9.2 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KXZ53674.1 - 1.7 8.7 17.0 3.1 7.9 4.6 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KXZ53674.1 - 1.9 8.5 4.4 1.5 8.8 1.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KXZ53674.1 - 2.5 8.6 31.3 0.066 13.7 4.6 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KXZ53674.1 - 5.5 7.0 24.1 0.1 12.6 8.2 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 KXZ53674.1 - 7.1 7.0 19.1 0.71 10.3 5.8 2.6 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cytochrom_C_2 PF01322.20 KXZ53674.1 - 7.1 7.5 10.8 1.6 9.6 6.3 2.2 2 1 0 2 2 2 0 Cytochrome C' DUF724 PF05266.14 KXZ53674.1 - 7.6 6.3 12.8 2.9 7.7 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 KXZ53674.1 - 8.6 6.8 18.3 6.3 7.2 5.8 2.1 1 1 1 2 2 2 0 Fez1 G-patch PF01585.23 KXZ53675.1 - 1.5e-16 60.0 2.7 5.1e-16 58.3 2.7 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXZ53675.1 - 1.2e-05 25.3 1.2 1.2e-05 25.3 1.2 2.9 2 0 0 2 2 2 1 G-patch domain SEEEED PF14797.6 KXZ53675.1 - 0.012 15.7 12.5 0.012 15.7 12.5 3.5 3 0 0 3 3 3 0 Serine-rich region of AP3B1, clathrin-adaptor complex Phage_GPO PF05929.11 KXZ53677.1 - 0.18 11.4 8.5 0.23 11.1 8.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3435 PF11917.8 KXZ53677.1 - 0.19 10.6 13.5 0.25 10.2 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FAM199X PF15814.5 KXZ53677.1 - 0.24 10.4 6.5 0.33 10.0 6.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X DDHD PF02862.17 KXZ53677.1 - 0.33 11.1 2.4 0.38 10.9 2.4 1.1 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 KXZ53677.1 - 0.46 9.4 12.9 0.62 9.0 12.9 1.1 1 0 0 1 1 1 0 Paf1 Plasmodium_Vir PF05795.11 KXZ53677.1 - 0.48 9.8 1.8 0.46 9.8 1.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.12 KXZ53677.1 - 0.66 9.7 12.8 0.9 9.3 12.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 KXZ53677.1 - 0.82 9.6 14.3 0.94 9.4 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop53 PF07767.11 KXZ53677.1 - 0.88 8.9 20.9 1.1 8.5 20.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Asp-B-Hydro_N PF05279.11 KXZ53677.1 - 0.93 9.5 10.9 1.1 9.2 10.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FAM60A PF15396.6 KXZ53677.1 - 1 9.3 6.4 1.4 8.9 6.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 KXZ53677.1 - 1.1 8.0 9.2 1.3 7.7 9.2 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KXZ53677.1 - 1.6 8.7 4.8 2 8.4 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 KXZ53677.1 - 1.8 7.4 5.6 2.1 7.2 5.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.6 KXZ53677.1 - 2.1 7.7 13.5 2.8 7.2 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 KXZ53677.1 - 2.5 6.3 11.1 3.1 6.0 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein VIR_N PF15912.5 KXZ53677.1 - 3.5 7.2 7.0 4.8 6.7 7.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal GREB1 PF15782.5 KXZ53677.1 - 3.9 4.5 5.2 4.2 4.4 5.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MAJIN PF15077.6 KXZ53677.1 - 3.9 7.2 6.3 5.1 6.8 6.3 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein MDM10 PF12519.8 KXZ53677.1 - 4.2 6.1 5.0 5 5.9 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 V_ATPase_I PF01496.19 KXZ53677.1 - 4.9 4.9 9.0 6.2 4.6 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.11 KXZ53677.1 - 6.6 5.1 18.1 8.4 4.8 18.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FancD2 PF14631.6 KXZ53677.1 - 7.7 3.8 6.6 9.5 3.5 6.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease FAST_1 PF06743.15 KXZ53678.1 - 0.18 11.8 0.0 5.6 7.0 0.0 3.0 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 1 Smg8_Smg9 PF10220.9 KXZ53679.1 - 0.00048 18.6 0.2 0.89 7.8 0.0 2.9 3 0 0 3 3 3 3 Smg8_Smg9 Mito_fiss_reg PF05308.11 KXZ53680.1 - 7.9 6.5 5.7 11 6.0 5.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator REJ PF02010.15 KXZ53681.1 - 1.7e-12 46.9 0.0 2.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 REJ domain Cadherin_4 PF17803.1 KXZ53681.1 - 1.1 10.0 6.2 0.92 10.2 0.6 3.5 3 0 0 3 3 3 0 Bacterial cadherin-like domain AAA_23 PF13476.6 KXZ53683.1 - 2e-08 35.0 0.0 3.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXZ53683.1 - 1.1e-06 28.2 0.0 3.2e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXZ53683.1 - 3.4e-06 26.7 0.0 3.6e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXZ53683.1 - 0.00019 21.8 2.4 0.00019 21.8 2.4 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXZ53683.1 - 0.00027 21.2 0.0 0.00099 19.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KXZ53683.1 - 0.016 15.0 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KXZ53683.1 - 0.034 14.7 0.3 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 KXZ53683.1 - 0.093 12.6 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 KXZ53683.1 - 0.23 11.1 0.0 0.32 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Nnf1 PF03980.14 KXZ53683.1 - 8.3 6.8 9.2 5 7.5 0.0 3.2 4 0 0 4 4 4 0 Nnf1 CN_hydrolase PF00795.22 KXZ53684.1 - 4.1e-22 78.8 0.1 4.5e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_16 PF10294.9 KXZ53685.1 - 7.5e-19 68.1 0.0 3.7e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase CN_hydrolase PF00795.22 KXZ53685.1 - 8.9e-17 61.3 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase IHABP4_N PF16174.5 KXZ53686.1 - 0.92 10.1 6.9 1.6 9.3 6.9 1.4 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal API5 PF05918.11 KXZ53686.1 - 1.5 7.6 3.6 1.8 7.3 3.6 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Hat1_N PF10394.9 KXZ53687.1 - 1.6e-15 57.7 0.0 1.6e-14 54.4 0.0 2.1 1 1 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KXZ53687.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 KXZ53687.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family TFIIA PF03153.13 KXZ53687.1 - 3.7 7.4 5.6 0.5 10.3 1.4 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ABC1 PF03109.16 KXZ53688.1 - 5.3e-23 81.4 0.0 1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family WD40 PF00400.32 KXZ53689.1 - 1.7e-11 44.4 2.5 0.00014 22.6 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.7 KXZ53689.1 - 0.015 15.2 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 F-box-like Bd3614-deam PF14439.6 KXZ53690.1 - 0.81 9.8 3.9 1.9 8.5 3.9 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase XPG_I PF00867.18 KXZ53691.1 - 2.9e-23 82.0 0.0 5.2e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXZ53691.1 - 6.5e-22 77.9 0.0 2.1e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 KXZ53691.1 - 2.4e-08 33.7 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_9 PF13371.6 KXZ53691.1 - 0.0014 18.8 3.0 0.0038 17.3 3.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ53691.1 - 0.0052 16.8 0.1 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ53691.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ53691.1 - 0.034 14.9 1.5 0.034 14.9 1.5 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ53691.1 - 0.063 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3701 PF12482.8 KXZ53691.1 - 0.14 12.3 0.0 15 5.7 0.0 2.8 3 0 0 3 3 3 0 Phage integrase protein TPR_7 PF13176.6 KXZ53691.1 - 0.18 11.9 0.5 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KXZ53693.1 - 3.9e-24 85.3 0.0 6.7e-23 81.3 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ53693.1 - 1.4e-21 77.1 0.0 3.6e-20 72.4 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ53693.1 - 0.0099 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ53693.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family EamA PF00892.20 KXZ53695.1 - 1.9e-06 28.1 16.5 0.0067 16.6 9.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family Lipoprotein_20 PF13942.6 KXZ53696.1 - 0.056 13.4 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 YfhG lipoprotein RICTOR_N PF14664.6 KXZ53696.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Malate_DH PF12434.8 KXZ53696.1 - 5.3 7.1 6.7 1 9.4 1.8 2.4 2 0 0 2 2 2 0 Malate dehydrogenase enzyme SUI1 PF01253.22 KXZ53698.1 - 2.2e-20 72.9 0.2 4.4e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 IQ PF00612.27 KXZ53698.1 - 0.00019 20.9 1.0 0.00055 19.5 1.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif AP2 PF00847.20 KXZ53699.1 - 1.7e-11 44.1 0.6 4.4e-11 42.8 0.6 1.8 1 0 0 1 1 1 1 AP2 domain ADP_ribosyl_GH PF03747.14 KXZ53700.1 - 9.4e-27 94.5 7.0 9.4e-27 94.5 7.0 2.1 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase MMR_HSR1 PF01926.23 KXZ53700.1 - 4e-14 52.7 0.0 6.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 KXZ53700.1 - 2.3e-13 50.5 21.4 4e-11 43.4 21.4 3.4 1 1 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 KXZ53700.1 - 2e-06 28.4 0.0 5.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal eIF3_subunit PF08597.10 KXZ53701.1 - 0.12 12.2 11.3 0.16 11.8 11.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RXLR PF16810.5 KXZ53701.1 - 1.7 9.1 5.7 1.5 9.3 4.7 1.5 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DNA_pol_phi PF04931.13 KXZ53701.1 - 2.5 6.1 6.9 2.9 5.9 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KXZ53701.1 - 3.4 5.9 9.6 3.8 5.7 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.27 KXZ53702.1 - 8.5e-33 112.2 8.2 3.8e-15 55.6 0.0 3.7 4 1 0 4 4 4 3 Mitochondrial carrier protein TFIID-31kDa PF02291.15 KXZ53703.1 - 5e-28 97.6 0.0 5.6e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KXZ53703.1 - 0.01 16.2 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 KXZ53703.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Ank_2 PF12796.7 KXZ53704.1 - 4.9e-17 62.3 3.5 0.00018 22.0 0.4 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53704.1 - 3.8e-13 49.6 8.6 0.023 15.3 0.4 6.3 5 0 0 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53704.1 - 6.6e-12 44.5 5.9 1.2 9.9 0.0 8.5 8 1 1 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 KXZ53704.1 - 9.3e-11 41.8 8.3 0.46 10.9 0.1 6.7 4 1 2 6 6 6 4 Ankyrin repeats (many copies) DUF4224 PF13986.6 KXZ53704.1 - 0.028 14.3 0.3 2.8 7.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4224) DUF5555 PF17710.1 KXZ53704.1 - 0.12 11.9 7.8 0.54 9.7 0.3 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5555) Ank PF00023.30 KXZ53704.1 - 1.4 9.5 3.6 14 6.4 0.1 4.1 5 1 0 5 5 5 0 Ankyrin repeat AMP-binding PF00501.28 KXZ53705.1 - 4.2e-90 302.4 0.0 5.2e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ53705.1 - 2e-23 83.1 0.2 4.7e-23 82.0 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXZ53705.1 - 4.3e-19 68.2 0.0 8.3e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DENN PF02141.21 KXZ53706.1 - 1.4e-16 61.0 0.1 5.9e-08 32.9 0.2 2.3 1 1 1 2 2 2 2 DENN (AEX-3) domain dDENN PF03455.19 KXZ53706.1 - 0.18 11.8 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 dDENN domain Ribosomal_L32p PF01783.23 KXZ53708.1 - 4.7e-06 26.8 1.2 7.8e-06 26.1 1.2 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family AAA_33 PF13671.6 KXZ53709.1 - 0.022 14.9 0.1 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain tRNA_lig_CPD PF08302.11 KXZ53709.1 - 0.083 12.3 0.1 0.57 9.6 0.1 2.2 2 1 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain CorA PF01544.18 KXZ53710.1 - 9e-08 31.8 6.2 1.2e-05 24.8 1.0 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF4692 PF15763.5 KXZ53710.1 - 0.028 14.9 0.7 0.047 14.2 0.7 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SDP_N PF12278.8 KXZ53710.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal SR-25 PF10500.9 KXZ53710.1 - 1.2 8.8 6.6 2 8.0 6.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2721 PF11026.8 KXZ53710.1 - 7 6.6 5.8 0.73 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) XG_FTase PF03254.13 KXZ53711.1 - 0.017 13.8 0.0 0.45 9.1 0.0 2.2 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase ribosomal_L24 PF17136.4 KXZ53712.1 - 3.2e-19 69.1 0.8 3.2e-19 69.1 0.8 2.0 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 KXZ53712.1 - 1.5e-08 34.2 7.7 4.7e-08 32.7 7.7 1.9 1 0 0 1 1 1 1 KOW motif SH3_2 PF07653.17 KXZ53712.1 - 0.043 13.5 0.4 0.37 10.5 0.4 2.2 1 1 0 1 1 1 0 Variant SH3 domain DUF4926 PF16277.5 KXZ53712.1 - 0.13 11.7 0.1 0.29 10.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4926) AAA PF00004.29 KXZ53715.1 - 7.4e-38 130.0 0.0 2.3e-37 128.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KXZ53715.1 - 4.2e-24 85.4 0.1 5.6e-23 81.8 0.1 2.2 1 1 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 KXZ53715.1 - 2.6e-07 30.3 0.3 6.8e-07 29.0 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXZ53715.1 - 7.5e-05 22.5 0.0 0.0021 17.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ53715.1 - 0.0037 17.5 0.8 2.4 8.4 0.1 3.4 2 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KXZ53715.1 - 0.0053 16.7 0.1 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXZ53715.1 - 0.012 16.2 0.0 0.032 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ53715.1 - 0.012 16.0 5.6 0.017 15.5 0.7 3.0 2 2 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KXZ53715.1 - 0.02 15.1 0.0 0.02 15.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KXZ53715.1 - 0.022 14.5 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 KXZ53715.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 KXZ53715.1 - 0.032 13.4 0.1 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KXZ53715.1 - 0.075 12.4 0.3 0.15 11.4 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KXZ53715.1 - 0.084 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 KXZ53715.1 - 0.11 12.4 1.6 2.4 8.1 0.5 2.9 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 KXZ53715.1 - 0.15 12.2 0.1 0.66 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXZ53715.1 - 0.19 11.3 1.5 0.62 9.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain Exo_endo_phos PF03372.23 KXZ53716.1 - 9.9e-11 41.6 0.2 1.9e-10 40.7 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KXZ53716.1 - 0.00082 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Pkinase_Tyr PF07714.17 KXZ53718.1 - 3.7e-23 82.1 0.0 4.3e-22 78.6 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ53718.1 - 5.1e-22 78.5 0.0 3.1e-21 75.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ53718.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ53718.1 - 0.24 11.0 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family mTERF PF02536.14 KXZ53719.1 - 6.7e-08 31.8 0.0 0.004 16.1 0.0 2.5 1 1 1 2 2 2 2 mTERF SpoU_methylase PF00588.19 KXZ53720.1 - 1.5e-20 73.8 0.0 2.1e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Pkinase_Tyr PF07714.17 KXZ53722.1 - 6.5e-26 91.2 0.0 3e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ53722.1 - 3.8e-22 78.9 0.0 9.3e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Rhodanese PF00581.20 KXZ53723.1 - 2.2e-12 47.4 0.0 2.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain AF2331-like PF14556.6 KXZ53723.1 - 0.091 13.3 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 AF2331-like Pkinase_Tyr PF07714.17 KXZ53724.1 - 3.2e-23 82.3 0.0 3.1e-22 79.1 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ53724.1 - 1.4e-19 70.5 0.0 1.7e-18 67.0 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ53724.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXZ53724.1 - 0.24 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family SET PF00856.28 KXZ53725.1 - 0.00064 20.1 0.0 0.57 10.5 0.0 2.8 2 1 1 3 3 3 2 SET domain Agenet PF05641.12 KXZ53725.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Agenet domain RRM_1 PF00076.22 KXZ53726.1 - 2.6e-08 33.6 0.0 0.016 15.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 KXZ53726.1 - 1.6 7.5 15.5 3 6.6 15.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dsh_C PF12316.8 KXZ53726.1 - 2.9 8.3 32.3 7.3 6.9 3.4 2.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal SMC_N PF02463.19 KXZ53727.1 - 2.7e-31 108.7 0.0 2.2e-30 105.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXZ53727.1 - 9.6e-15 55.2 0.0 5.6e-06 26.4 0.3 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXZ53727.1 - 2.3e-07 31.5 6.9 4.1e-07 30.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KXZ53727.1 - 6.9e-06 26.6 0.0 0.0015 19.1 0.0 3.0 2 0 0 2 2 2 1 ABC transporter AAA_15 PF13175.6 KXZ53727.1 - 0.0018 18.0 0.0 0.0093 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KXZ53727.1 - 0.024 14.4 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 KXZ53727.1 - 0.048 13.6 0.0 0.89 9.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KXZ53727.1 - 0.1 12.9 0.1 6.9 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KXZ53727.1 - 0.14 12.6 0.0 15 6.0 0.2 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 KXZ53728.1 - 3.2e-32 111.6 0.0 4.2e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ53728.1 - 7.6e-26 91.1 0.0 9.8e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ53728.1 - 1.9e-05 24.7 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXZ53728.1 - 0.00047 19.6 0.0 0.00065 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KXZ53729.1 - 1.1e-31 109.8 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ53729.1 - 1.3e-23 83.8 0.0 1.8e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXZ53729.1 - 1.3e-05 24.7 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KXZ53729.1 - 2.1e-05 24.5 0.0 5.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Acetyltransf_7 PF13508.7 KXZ53730.1 - 4e-05 24.0 0.0 0.00011 22.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ53730.1 - 7e-05 23.0 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ53730.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ53730.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein OB_NTP_bind PF07717.16 KXZ53731.1 - 8.2e-13 48.5 0.0 1.6e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Acetyltransf_7 PF13508.7 KXZ53732.1 - 6.8e-05 23.2 0.0 0.00023 21.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ53732.1 - 0.00012 22.3 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ53732.1 - 0.044 13.7 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_4 PF07721.14 KXZ53732.1 - 3 8.8 6.9 45 5.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HA2 PF04408.23 KXZ53733.1 - 8.6e-18 64.6 0.1 1.3e-16 60.8 0.0 3.2 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXZ53733.1 - 3.4e-12 46.5 0.0 6.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXZ53733.1 - 3.1e-09 37.1 0.0 1.1e-08 35.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Rubis-subs-bind PF09273.11 KXZ53733.1 - 0.00011 22.9 0.4 0.017 15.8 0.1 3.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DEAD PF00270.29 KXZ53733.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXZ53733.1 - 0.048 13.9 0.5 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXZ53733.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KXZ53733.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 KaiC Pkinase PF00069.25 KXZ53734.1 - 2.1e-29 102.7 0.0 6.6e-20 71.6 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53734.1 - 9.8e-29 100.4 1.0 5.8e-15 55.3 0.1 3.0 1 1 1 3 3 3 3 Protein tyrosine kinase Prok-E2_C PF14459.6 KXZ53734.1 - 0.0077 16.4 0.4 0.015 15.5 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic E2 family C APH PF01636.23 KXZ53734.1 - 0.025 14.5 1.2 0.058 13.3 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ53735.1 - 1.1e-09 38.1 0.0 7.8e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53735.1 - 2.4e-08 33.6 0.0 5.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3717 PF12512.8 KXZ53737.1 - 0.13 12.2 2.3 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) RVT_1 PF00078.27 KXZ53738.1 - 1.8e-19 70.2 0.0 2e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DGOK PF05035.12 KXZ53738.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase Pkinase PF00069.25 KXZ53739.1 - 5.8e-30 104.5 0.0 5.2e-22 78.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53739.1 - 1.1e-28 100.3 0.0 4.3e-26 91.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 KXZ53740.1 - 2e-22 77.3 8.1 2.6e-05 23.9 0.0 7.7 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 KXZ53740.1 - 3.5e-07 30.4 5.0 0.25 11.8 0.0 5.4 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ53740.1 - 0.0061 16.9 0.2 1.4e+02 3.7 0.0 5.6 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 KXZ53740.1 - 0.054 13.3 11.6 1.7 8.5 1.1 5.7 4 3 1 5 5 5 0 Leucine rich repeat zf-MYND PF01753.18 KXZ53741.1 - 2e-09 37.4 11.7 4e-09 36.4 11.7 1.6 1 0 0 1 1 1 1 MYND finger Glyco_transf_90 PF05686.12 KXZ53742.1 - 0.37 9.6 1.1 12 4.7 0.5 2.7 2 1 0 2 2 2 0 Glycosyl transferase family 90 Pkinase_Tyr PF07714.17 KXZ53743.1 - 8.9e-25 87.4 0.0 5.1e-14 52.2 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ53743.1 - 3.9e-15 55.9 0.0 1.8e-06 27.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Kdo PF06293.14 KXZ53743.1 - 0.24 10.7 0.0 0.46 9.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Guanylate_cyc PF00211.20 KXZ53744.1 - 1.1e-06 28.5 0.0 1.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain EF-hand_1 PF00036.32 KXZ53746.1 - 3.1e-37 123.4 5.2 5.7e-06 25.5 0.0 7.8 7 1 0 7 7 7 7 EF hand EF-hand_7 PF13499.6 KXZ53746.1 - 8.4e-37 125.5 0.2 3.7e-10 40.1 0.7 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KXZ53746.1 - 6.1e-30 100.6 5.4 0.0001 21.9 0.0 8.1 7 2 1 8 8 8 6 EF-hand domain EF-hand_8 PF13833.6 KXZ53746.1 - 8.8e-25 86.3 1.1 2e-07 30.7 0.0 6.7 4 2 2 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 KXZ53746.1 - 6.7e-24 82.3 0.1 0.00013 21.3 0.0 6.0 5 0 0 5 5 5 5 EF hand SPARC_Ca_bdg PF10591.9 KXZ53746.1 - 3.2e-07 30.6 1.2 0.019 15.3 0.1 4.2 4 2 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KXZ53746.1 - 1.7e-05 24.6 6.1 2 8.4 0.1 5.7 4 2 2 6 6 6 3 EF hand DUF5580 PF17743.1 KXZ53746.1 - 2.5e-05 23.0 0.3 2 6.9 0.1 3.9 1 1 1 3 3 3 3 Family of unknown function (DUF5580) EF-hand_4 PF12763.7 KXZ53746.1 - 0.0001 22.2 8.3 0.31 11.0 0.9 4.7 2 1 2 5 5 5 2 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 KXZ53746.1 - 0.015 15.4 0.4 15 5.7 0.1 3.8 2 1 0 3 3 3 0 p25-alpha UBA_6 PF18039.1 KXZ53746.1 - 0.023 14.6 0.3 0.79 9.7 0.0 3.5 4 0 0 4 4 4 0 UBA-like domain Lyase_8_N PF08124.11 KXZ53746.1 - 0.062 12.2 0.0 0.16 10.9 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain EF-hand_11 PF08976.11 KXZ53746.1 - 0.064 14.1 0.2 9.1 7.2 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain Toprim_2 PF13155.6 KXZ53746.1 - 0.068 13.6 2.7 5.9 7.4 0.0 3.8 4 0 0 4 4 4 0 Toprim-like CPBP PF02517.16 KXZ53747.1 - 6e-14 52.2 2.3 6e-14 52.2 2.3 1.6 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Wbp11 PF09429.10 KXZ53748.1 - 3.8e-16 59.2 11.2 3.8e-16 59.2 11.2 1.8 1 1 1 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.7 KXZ53748.1 - 0.017 15.9 22.9 0.66 10.8 22.9 2.9 1 1 0 1 1 1 0 mRNA biogenesis factor BPD_transp_1 PF00528.22 KXZ53749.1 - 8.3e-22 77.8 9.3 1.2e-21 77.3 9.3 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component COX14 PF14880.6 KXZ53749.1 - 0.35 10.8 0.1 0.35 10.8 0.1 2.1 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Col_cuticle_N PF01484.17 KXZ53749.1 - 4.3 7.5 12.0 0.84 9.7 0.1 3.3 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Galactosyl_T PF01762.21 KXZ53750.1 - 3.3e-15 56.4 0.0 6.6e-08 32.6 0.0 3.2 3 0 0 3 3 3 3 Galactosyltransferase S1 PF00575.23 KXZ53751.1 - 0.00058 20.1 0.1 0.001 19.4 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Pkinase PF00069.25 KXZ53752.1 - 8.1e-60 202.4 0.0 1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53752.1 - 1.7e-24 86.5 0.0 2.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ53752.1 - 5.6e-06 25.9 0.0 0.11 11.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KXZ53752.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ53752.1 - 0.035 12.9 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXZ53752.1 - 0.063 13.2 0.3 3 7.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF5083 PF16890.5 KXZ53752.1 - 0.27 10.9 0.0 0.42 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Nop53 PF07767.11 KXZ53755.1 - 4.6e-54 184.3 9.4 4.6e-54 184.3 9.4 2.4 2 1 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) LegC3_N PF18654.1 KXZ53755.1 - 0.17 11.1 7.9 0.28 10.4 7.9 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain S6PP PF05116.13 KXZ53756.1 - 3e-26 92.5 0.0 2.4e-16 60.1 0.0 3.2 1 1 2 3 3 3 3 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 KXZ53756.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ASH PF15780.5 KXZ53757.1 - 1.7e-34 117.9 4.0 0.00085 19.5 0.0 11.3 11 2 1 12 12 12 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KXZ53757.1 - 6.6e-18 64.7 7.3 0.007 16.5 0.0 8.1 8 0 0 8 8 8 4 Flagellar-associated PapD-like TMEM131_like PF12371.8 KXZ53757.1 - 2e-12 47.2 7.6 0.0073 16.5 0.1 7.9 9 1 0 9 9 9 3 Transmembrane protein 131-like Motile_Sperm PF00635.26 KXZ53757.1 - 4.8e-12 45.7 0.0 0.0059 16.4 0.0 6.6 7 0 0 7 7 7 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 KXZ53757.1 - 0.00027 20.9 0.0 4.9 7.3 0.0 5.8 6 1 0 6 6 6 1 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 KXZ53757.1 - 0.00067 18.7 0.0 3.6 6.4 0.0 5.4 5 1 1 6 6 6 1 MYCBP-associated protein family DUF11 PF01345.18 KXZ53757.1 - 0.86 9.9 11.5 38 4.7 0.0 7.5 8 1 0 8 8 8 0 Domain of unknown function DUF11 Radical_SAM_C PF16199.5 KXZ53758.1 - 8.6e-31 105.8 0.0 1.8e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KXZ53758.1 - 2.1e-17 64.0 0.1 4.7e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KXZ53758.1 - 5.6e-09 36.3 0.1 1.3e-08 35.0 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ53758.1 - 2.7e-05 24.1 0.3 5.9e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ53758.1 - 2.8e-05 24.5 0.0 5.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ53758.1 - 0.012 15.6 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 FR47-like protein YcaO PF02624.16 KXZ53758.1 - 0.053 12.8 0.2 0.12 11.6 0.1 1.6 2 0 0 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding APC_N_CC PF16689.5 KXZ53759.1 - 0.17 12.0 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain PRKG1_interact PF15898.5 KXZ53759.1 - 1.3 10.0 0.1 1.3 10.0 0.1 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain JIP_LZII PF16471.5 KXZ53759.1 - 4.7 7.5 6.7 14 5.9 0.3 2.5 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II KDZ PF18758.1 KXZ53760.1 - 3.8e-12 46.3 0.0 1.9e-10 40.8 0.0 2.2 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase Transposase_22 PF02994.14 KXZ53761.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 L1 transposable element RBD-like domain PCI PF01399.27 KXZ53762.1 - 1.2e-11 45.0 0.0 3.8e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 PCI domain SPO22 PF08631.10 KXZ53762.1 - 0.0095 15.5 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KXZ53763.1 - 2.1e-06 27.9 0.4 2.1e-06 27.9 0.4 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ53763.1 - 1.7 8.6 8.1 20 5.2 2.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Calreticulin PF00262.18 KXZ53765.1 - 1.4e-58 198.6 0.0 1.5e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Calreticulin family Ribosomal_L22e PF01776.17 KXZ53766.1 - 2.2e-45 153.5 5.0 2.7e-45 153.2 5.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Phyto-Amp PF15438.6 KXZ53766.1 - 0.01 15.7 0.7 0.012 15.5 0.7 1.3 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma DsbD PF02683.15 KXZ53767.1 - 2e-37 129.1 3.1 2.4e-37 128.9 3.1 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 KXZ53767.1 - 5.6e-07 29.7 9.8 8.5e-07 29.1 9.8 1.3 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF308 PF03729.13 KXZ53767.1 - 0.71 10.2 10.7 1.9 8.9 1.7 2.5 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Claudin_2 PF13903.6 KXZ53767.1 - 2 8.1 8.6 0.81 9.4 1.7 2.6 2 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Serinc PF03348.15 KXZ53768.1 - 2.5e-49 168.4 11.5 2.1e-23 83.0 2.2 3.0 1 1 2 3 3 3 3 Serine incorporator (Serinc) Pollen_allerg_1 PF01357.21 KXZ53768.1 - 0.068 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Pollen allergen ING PF12998.7 KXZ53771.1 - 1e-13 51.7 0.1 1.9e-13 50.9 0.1 1.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding COMPASS-Shg1 PF05205.12 KXZ53772.1 - 0.0022 18.7 0.7 0.0058 17.3 0.7 1.7 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 IQ PF00612.27 KXZ53774.1 - 0.99 9.4 3.0 2.8 8.0 3.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif RR_TM4-6 PF06459.12 KXZ53774.1 - 1 9.1 8.3 1.7 8.4 8.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PspA_IM30 PF04012.12 KXZ53775.1 - 9.5e-45 152.9 27.2 1.1e-44 152.6 27.2 1.1 1 0 0 1 1 1 1 PspA/IM30 family Exonuc_VII_L PF02601.15 KXZ53775.1 - 0.029 14.0 6.7 0.045 13.3 6.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 KXZ53775.1 - 0.039 14.3 6.4 0.64 10.4 0.0 3.2 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF465 PF04325.13 KXZ53775.1 - 0.21 11.7 4.1 3.8 7.6 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF465) Fib_alpha PF08702.10 KXZ53775.1 - 0.36 11.0 5.1 0.91 9.7 4.7 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PIN_8 PF18476.1 KXZ53775.1 - 0.61 9.9 6.9 6.4 6.6 0.2 2.1 1 1 1 2 2 2 0 PIN like domain DUF4094 PF13334.6 KXZ53775.1 - 0.67 10.4 4.5 0.65 10.5 2.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) ERM PF00769.19 KXZ53775.1 - 1 9.2 24.6 1 9.1 12.3 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 KXZ53775.1 - 1.4 9.0 9.9 0.5 10.4 3.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXZ53775.1 - 3.9 6.3 18.1 8.4 5.2 18.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4239 PF14023.6 KXZ53775.1 - 4.9 6.8 6.3 2 8.1 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) CBM_10 PF02013.16 KXZ53776.1 - 0.18 12.3 0.5 0.18 12.3 0.5 2.2 2 0 0 2 2 2 0 Cellulose or protein binding domain P-II PF00543.22 KXZ53778.1 - 2e-28 99.0 0.0 2.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II UDPG_MGDP_dh_N PF03721.14 KXZ53779.1 - 7.9e-64 214.7 0.1 1.3e-63 213.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KXZ53779.1 - 3e-34 117.6 0.0 7.8e-34 116.3 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KXZ53779.1 - 1.5e-31 108.5 0.1 2.9e-31 107.5 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 KXZ53779.1 - 0.04 13.8 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXZ53779.1 - 0.047 14.0 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain p450 PF00067.22 KXZ53780.1 - 1.5e-10 40.5 0.0 2e-07 30.2 0.0 2.5 3 0 0 3 3 3 2 Cytochrome P450 DUF2285 PF10074.9 KXZ53783.1 - 0.71 10.6 6.1 0.17 12.6 1.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) DUF1180 PF06679.12 KXZ53784.1 - 0.71 10.3 15.4 0.38 11.1 9.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4512 PF14975.6 KXZ53784.1 - 0.78 10.6 4.3 2.2 9.1 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) PRR18 PF15671.5 KXZ53784.1 - 2.2 8.1 21.1 0.38 10.6 1.1 2.5 2 0 0 2 2 2 0 Proline-rich protein family 18 RicinB_lectin_2 PF14200.6 KXZ53785.1 - 2e-41 140.6 22.8 7.9e-17 61.8 0.2 5.2 2 1 3 5 5 5 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ53785.1 - 8.2e-35 119.8 6.7 6.5e-17 62.0 4.7 2.7 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ53785.1 - 7.1e-34 117.4 3.2 1.9e-33 116.0 0.3 2.6 3 0 0 3 3 3 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ53785.1 - 2.3e-12 46.7 1.5 1.5e-05 24.7 0.1 2.5 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain EF-hand_1 PF00036.32 KXZ53785.1 - 0.00013 21.2 0.3 0.00028 20.2 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ53785.1 - 0.0015 18.3 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXZ53785.1 - 0.016 14.7 0.2 0.031 13.8 0.2 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KXZ53785.1 - 0.021 15.3 0.2 0.041 14.3 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KXZ53785.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KXZ53786.1 - 5e-06 25.7 0.3 9.1e-06 24.9 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ53786.1 - 6.1e-05 22.6 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ53786.1 - 0.0007 20.0 0.1 0.00098 19.5 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ53786.1 - 0.00074 18.9 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ53786.1 - 0.0051 16.6 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair L27 PF02828.16 KXZ53786.1 - 0.1 12.4 0.4 0.35 10.7 0.1 1.8 2 0 0 2 2 2 0 L27 domain TssO PF17561.2 KXZ53786.1 - 0.11 12.7 0.3 0.16 12.1 0.0 1.4 2 0 0 2 2 2 0 Type VI secretion system, TssO VOMI PF03762.17 KXZ53787.1 - 0.00093 19.4 0.0 0.0033 17.6 0.0 1.9 1 1 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) RicinB_lectin_2 PF14200.6 KXZ53788.1 - 1.3e-40 138.0 17.9 9.8e-13 48.6 2.5 4.5 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ53788.1 - 2e-33 115.3 10.3 2.7e-17 63.2 5.3 3.5 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain VOMI PF03762.17 KXZ53788.1 - 6.7e-17 62.1 1.7 1.2e-16 61.3 0.6 2.0 2 0 0 2 2 2 1 Vitelline membrane outer layer protein I (VOMI) CDtoxinA PF03498.14 KXZ53788.1 - 1.4e-13 50.7 3.7 1.5e-06 27.8 0.5 2.5 1 1 0 2 2 2 2 Cytolethal distending toxin A/C domain PPC PF04151.15 KXZ53788.1 - 0.27 12.4 2.9 4.5 8.4 0.4 2.8 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain DEC-1_N PF04625.13 KXZ53790.1 - 0.37 9.8 7.0 0.41 9.6 7.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Cupin_4 PF08007.12 KXZ53791.1 - 1.7e-43 149.4 0.0 7.1e-41 140.7 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.6 KXZ53791.1 - 8e-06 25.7 5.5 4.5e-05 23.3 0.0 2.9 2 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 KXZ53791.1 - 0.0077 15.9 0.0 0.0077 15.9 0.0 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KXZ53791.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupin CDC50 PF03381.15 KXZ53793.1 - 3.1e-18 66.3 0.0 3.9e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family G-patch PF01585.23 KXZ53794.1 - 7.7e-09 35.3 4.2 1.3e-07 31.3 1.6 3.0 2 0 0 2 2 2 2 G-patch domain WD40 PF00400.32 KXZ53795.1 - 3.7e-21 75.0 10.2 5.3e-05 23.9 0.3 7.2 6 2 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ53795.1 - 0.0099 16.2 0.0 1.8 8.9 0.0 3.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Trp_oprn_chp PF09534.10 KXZ53797.1 - 8.5 6.1 10.2 0.28 10.9 1.1 2.2 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) GMP_PDE_delta PF05351.11 KXZ53800.1 - 2e-62 209.9 0.6 2.3e-62 209.7 0.6 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Transketolase_C PF02780.20 KXZ53801.1 - 3.7e-28 97.9 0.0 4.4e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain Alba PF01918.21 KXZ53801.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Alba PFOR_II PF17147.4 KXZ53801.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Transket_pyr PF02779.24 KXZ53802.1 - 9.5e-15 54.7 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Ank_2 PF12796.7 KXZ53804.1 - 3.1e-06 27.7 1.0 0.00056 20.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ53804.1 - 0.0015 19.0 0.8 1.1 10.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ53804.1 - 0.0043 17.3 4.7 2.2 8.7 0.0 4.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ53804.1 - 0.0044 17.4 2.1 69 4.5 0.0 4.7 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 KXZ53804.1 - 0.098 13.1 3.3 34 5.1 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat p450 PF00067.22 KXZ53805.1 - 1.2e-54 185.8 0.0 1.7e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 KXZ53805.1 - 0.034 14.1 2.7 0.97 9.3 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 KXZ53806.1 - 5.5e-22 78.3 0.1 1.3e-10 41.2 0.0 3.2 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain DUF4439 PF14530.6 KXZ53806.1 - 0.022 15.5 0.0 0.085 13.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) Guanylate_cyc PF00211.20 KXZ53807.1 - 4.3e-09 36.3 0.0 3.6e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ53808.1 - 2.2e-07 30.7 0.0 3.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Usp PF00582.26 KXZ53810.1 - 4.2e-38 131.0 8.9 3.1e-26 92.6 4.1 2.7 2 1 0 2 2 2 2 Universal stress protein family GARS_N PF02844.15 KXZ53810.1 - 0.085 13.7 0.1 25 5.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain NADH_Oxid_Nqo15 PF11497.8 KXZ53812.1 - 0.1 12.6 1.1 0.19 11.8 1.1 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 Ammonium_transp PF00909.21 KXZ53813.1 - 2.6e-107 359.0 25.2 3.3e-107 358.7 25.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Pyr_redox_2 PF07992.14 KXZ53814.1 - 5e-39 134.3 0.1 6e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ53814.1 - 5.1e-21 75.2 0.0 8.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ53814.1 - 3.8e-18 65.8 0.1 1.4e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXZ53814.1 - 0.00082 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KXZ53814.1 - 0.0022 18.4 0.1 0.011 16.1 0.0 2.2 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.14 KXZ53814.1 - 0.0078 15.0 0.0 2.1 7.0 0.0 2.8 4 0 0 4 4 4 2 HI0933-like protein GIDA PF01134.22 KXZ53814.1 - 0.015 14.4 1.0 6 5.8 0.0 3.2 3 1 1 4 4 4 0 Glucose inhibited division protein A DUF4774 PF15999.5 KXZ53814.1 - 0.1 12.4 0.4 0.33 10.8 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) FAD_binding_3 PF01494.19 KXZ53814.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain EamA PF00892.20 KXZ53815.1 - 1.7e-25 89.8 30.6 1.1e-14 54.8 10.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family RRM_DME PF15628.6 KXZ53816.1 - 1.3e-12 47.8 0.0 1.6e-07 31.4 0.0 2.2 1 1 0 2 2 2 2 RRM in Demeter Yippee-Mis18 PF03226.14 KXZ53816.1 - 9.1e-07 29.1 0.1 1.2e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DnaJ PF00226.31 KXZ53817.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain HhH-GPD PF00730.25 KXZ53817.1 - 0.061 13.8 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.9 KXZ53817.1 - 2.2 8.7 5.1 4.6 7.7 5.1 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Pkinase PF00069.25 KXZ53818.1 - 4.4e-41 141.0 0.0 6.2e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53818.1 - 8.8e-22 77.6 0.0 1.1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ53818.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bestrophin PF01062.21 KXZ53819.1 - 2.4e-08 33.7 2.9 3.9e-05 23.2 0.2 3.3 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF3325 PF11804.8 KXZ53819.1 - 1.2 9.3 6.9 3.6 7.8 6.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) Pkinase PF00069.25 KXZ53820.1 - 1.3e-70 237.8 0.0 1.5e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53820.1 - 3.2e-34 118.4 0.0 4.2e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ53820.1 - 4.4e-05 22.9 0.0 0.00011 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXZ53820.1 - 0.0044 16.0 0.7 0.0088 15.0 0.7 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXZ53820.1 - 0.063 12.6 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXZ53820.1 - 0.14 11.8 0.9 0.19 11.3 0.9 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase ShK PF01549.24 KXZ53821.1 - 1.6e-05 25.4 5.9 1.6e-05 25.4 5.9 2.5 2 1 0 2 2 2 1 ShK domain-like PRKCSH PF07915.13 KXZ53821.1 - 0.0029 18.6 0.0 0.0058 17.6 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KXZ53821.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Peptidase_M11 PF05548.11 KXZ53822.1 - 1.7e-25 89.8 7.3 1.7e-25 89.8 7.3 1.5 2 0 0 2 2 2 1 Gametolysin peptidase M11 Reprolysin_5 PF13688.6 KXZ53822.1 - 0.00028 21.1 3.8 0.00052 20.2 3.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Cu-binding_MopE PF11617.8 KXZ53822.1 - 0.022 15.0 0.5 0.053 13.7 0.5 1.7 1 0 0 1 1 1 0 Putative metal-binding motif Peptidase_M66 PF10462.9 KXZ53822.1 - 0.053 12.5 0.8 0.083 11.8 0.8 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 KXZ53822.1 - 0.055 14.0 0.5 0.17 12.4 0.5 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXZ53822.1 - 0.45 10.1 2.7 0.36 10.4 0.7 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Exo70 PF03081.15 KXZ53823.1 - 3.5e-62 210.6 0.0 3.3e-30 105.4 0.0 2.4 3 0 0 3 3 3 2 Exo70 exocyst complex subunit MinE PF03776.14 KXZ53824.1 - 8.3e-05 22.5 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE CRS1_YhbY PF01985.21 KXZ53825.1 - 5.1e-10 39.4 0.2 7.7e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain PTP_tm PF18861.1 KXZ53827.1 - 0.042 13.9 0.1 0.064 13.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5399 PF17377.2 KXZ53828.1 - 0.039 13.8 0.0 0.048 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5399) PSI_PsaE PF02427.17 KXZ53829.1 - 3.4e-32 109.9 0.6 4.5e-32 109.5 0.6 1.2 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IV / PsaE Xpo1 PF08389.12 KXZ53830.1 - 9.5e-05 22.5 0.0 0.00029 20.9 0.0 1.8 1 1 0 1 1 1 1 Exportin 1-like protein ATP-synt_Eps PF04627.13 KXZ53831.1 - 1.6e-16 60.0 0.1 2e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain CHDCT2 PF08074.11 KXZ53831.1 - 0.2 11.9 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Ribosomal_L7Ae PF01248.26 KXZ53832.1 - 1.4e-24 85.7 0.2 1.6e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Urocanase_N PF17391.2 KXZ53832.1 - 0.062 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Urocanase N-terminal domain Peptidase_C50 PF03568.17 KXZ53833.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C50 ATP-synt_ab_C PF00306.27 KXZ53834.1 - 5.5e-10 39.6 0.0 1.9e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta chain, C terminal domain MtN3_slv PF03083.16 KXZ53835.1 - 1.2e-14 54.1 3.5 1.4e-06 28.2 0.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF4181 PF13789.6 KXZ53836.1 - 0.091 13.0 0.0 0.18 12.0 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) DUF308 PF03729.13 KXZ53836.1 - 0.28 11.5 10.8 0.21 11.9 5.2 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) SseC PF04888.12 KXZ53836.1 - 2.1 7.9 7.9 2.4 7.7 7.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CD20 PF04103.15 KXZ53836.1 - 2.4 8.2 11.6 1.7 8.7 7.2 2.0 1 1 1 2 2 2 0 CD20-like family Trp_oprn_chp PF09534.10 KXZ53836.1 - 4 7.2 21.7 0.81 9.5 8.2 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Fasciclin PF02469.22 KXZ53837.1 - 5.2e-06 26.7 0.0 9.5e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain Hint PF01079.20 KXZ53838.1 - 1.1e-17 64.2 0.0 4.1e-17 62.4 0.0 1.7 2 0 0 2 2 2 1 Hint module EF-hand_5 PF13202.6 KXZ53838.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KXZ53838.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF347 PF03988.12 KXZ53838.1 - 2.7 8.2 6.4 1.2 9.3 0.8 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) NAD_Gly3P_dh_N PF01210.23 KXZ53839.1 - 3.2e-39 134.4 0.0 5.1e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KXZ53839.1 - 4e-36 124.4 0.0 3.1e-35 121.5 0.0 2.5 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus HAD PF12710.7 KXZ53839.1 - 5e-12 46.6 0.0 1.3e-11 45.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ53839.1 - 1.2e-11 45.3 1.1 7e-11 42.8 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Semialdhyde_dh PF01118.24 KXZ53839.1 - 0.00039 20.8 0.0 0.0015 19.0 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXZ53839.1 - 0.0098 16.5 0.0 0.056 14.0 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_C PF07479.14 KXZ53840.1 - 3.1e-40 137.8 0.0 7.6e-40 136.5 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KXZ53840.1 - 3.1e-40 137.7 0.0 5e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HAD PF12710.7 KXZ53840.1 - 1.7e-11 44.9 0.0 5.2e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ53840.1 - 1.6e-10 41.6 0.0 7.7e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Semialdhyde_dh PF01118.24 KXZ53840.1 - 0.00095 19.6 0.0 0.0038 17.6 0.0 2.0 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXZ53840.1 - 0.0037 17.8 0.0 0.051 14.2 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent HAD_2 PF13419.6 KXZ53840.1 - 0.17 12.0 0.0 22 5.1 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KXZ53840.1 - 0.19 11.3 0.0 1.1 8.8 0.0 2.1 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF4509 PF14970.6 KXZ53841.1 - 1.2e-05 25.3 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) Bax1-I PF01027.20 KXZ53842.1 - 5e-44 150.6 22.4 5.7e-44 150.4 22.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KXZ53842.1 - 0.002 17.7 20.8 0.0042 16.7 20.8 1.5 1 1 0 1 1 1 1 Bax inhibitor 1 like DUF2448 PF10476.9 KXZ53842.1 - 0.15 11.9 3.7 0.24 11.2 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Hint PF01079.20 KXZ53843.1 - 2.6e-17 63.0 0.0 9.8e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 Hint module EF-hand_5 PF13202.6 KXZ53843.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 EF hand DUF347 PF03988.12 KXZ53843.1 - 4.6 7.5 7.3 1.3 9.2 1.1 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) WD40 PF00400.32 KXZ53844.1 - 1.2e-82 269.6 39.5 1.2e-08 35.4 0.1 12.9 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ53844.1 - 2.3e-48 162.4 8.5 5.9e-07 29.7 0.1 11.0 2 2 8 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ53844.1 - 2.2e-13 50.5 0.0 0.03 14.2 0.0 5.0 3 2 0 4 4 4 4 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXZ53844.1 - 4.5e-13 48.9 0.1 0.4 9.6 0.0 8.7 2 2 7 11 11 11 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXZ53844.1 - 1.1e-08 34.7 9.4 2.2 8.3 0.0 9.6 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KXZ53844.1 - 1.2e-05 23.6 1.0 0.12 10.4 0.0 4.6 4 1 0 4 4 4 2 IKI3 family PALB2_WD40 PF16756.5 KXZ53844.1 - 0.0011 18.0 18.4 0.32 9.9 0.3 4.7 3 2 1 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KXZ53844.1 - 0.087 11.3 0.1 4 5.9 0.0 3.3 3 1 1 4 4 4 0 Cytochrome D1 heme domain NACHT PF05729.12 KXZ53844.1 - 0.088 12.7 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Nup160 PF11715.8 KXZ53844.1 - 0.13 10.9 7.0 13 4.3 0.4 5.0 3 2 3 6 6 6 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXZ53844.1 - 0.21 10.9 9.8 35 3.6 0.0 6.5 3 3 4 7 7 7 0 Neuroblastoma-amplified sequence, N terminal Peptidase_S28 PF05577.12 KXZ53845.1 - 2.8e-65 220.8 0.0 3.8e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KXZ53845.1 - 0.0002 20.9 0.3 0.00036 20.1 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 KXZ53845.1 - 0.0043 15.8 0.1 0.0065 15.2 0.1 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 KXZ53845.1 - 0.0078 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ53845.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L12_N PF16320.5 KXZ53845.1 - 0.49 10.1 1.5 31 4.4 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain Complex1_51K PF01512.17 KXZ53846.1 - 7.3e-49 165.5 0.0 1.3e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KXZ53846.1 - 1.8e-30 104.8 0.1 3.4e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KXZ53846.1 - 1.7e-07 31.0 0.0 4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain CAP_N PF01213.19 KXZ53846.1 - 0.0059 16.1 1.1 0.01 15.3 1.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DUF3754 PF12576.8 KXZ53848.1 - 1.5e-16 60.6 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) zf-RING_2 PF13639.6 KXZ53849.1 - 3.5e-08 33.7 3.8 6e-08 32.9 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXZ53849.1 - 3.8e-06 26.5 6.7 6.7e-06 25.7 6.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXZ53849.1 - 1.5e-05 24.7 3.2 2.6e-05 24.0 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ53849.1 - 9.5e-05 22.3 1.7 0.00017 21.6 1.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXZ53849.1 - 0.0008 19.6 2.5 0.0017 18.6 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXZ53849.1 - 0.0031 17.5 2.8 0.0085 16.1 2.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KXZ53849.1 - 0.0088 15.9 1.3 0.015 15.2 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ53849.1 - 0.12 12.4 2.5 0.2 11.6 2.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain WSC PF01822.19 KXZ53850.1 - 0.00023 21.3 0.5 0.00062 19.9 0.5 1.8 1 0 0 1 1 1 1 WSC domain Glyco_transf_8 PF01501.20 KXZ53851.1 - 2.2e-05 24.2 0.2 0.00033 20.3 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KXZ53851.1 - 0.029 13.7 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative HC2 PF07382.11 KXZ53852.1 - 0.29 11.2 18.8 0.32 11.1 18.8 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 VlpA_repeat PF04649.12 KXZ53852.1 - 8.4 6.9 11.5 27 5.3 1.0 3.5 3 0 0 3 3 3 0 Mycoplasma hyorhinis VlpA repeat AhpC-TSA PF00578.21 KXZ53853.1 - 1.6e-31 108.8 0.0 2.2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ53853.1 - 3.9e-21 75.3 0.0 4.8e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KXZ53853.1 - 0.002 18.3 0.0 0.003 17.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme NOG1 PF06858.14 KXZ53853.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) Thioredoxin_8 PF13905.6 KXZ53853.1 - 0.035 14.4 0.0 0.051 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like E1-E2_ATPase PF00122.20 KXZ53854.1 - 3.4e-38 131.0 5.9 9.2e-37 126.3 2.8 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXZ53854.1 - 2.4e-29 103.1 17.2 1.6e-28 100.5 17.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXZ53854.1 - 2.2e-06 28.0 0.2 5.7e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain HA PF03457.14 KXZ53855.1 - 0.12 12.8 16.2 17 5.8 0.1 5.4 3 2 2 5 5 5 0 Helicase associated domain zf-piccolo PF05715.13 KXZ53855.1 - 1.4 9.1 6.8 2.9 8.1 6.8 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger Paired_CXXCH_1 PF09699.10 KXZ53855.1 - 1.5 8.6 3.7 0.47 10.2 0.2 2.0 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Pkinase_Tyr PF07714.17 KXZ53856.1 - 5.4e-33 114.4 0.0 6.5e-30 104.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ53856.1 - 2.8e-27 95.7 0.0 2e-21 76.6 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain APH PF01636.23 KXZ53856.1 - 0.00056 19.9 0.0 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ53856.1 - 0.0021 16.9 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ53856.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXZ53857.1 - 1.5e-32 113.0 0.0 2.4e-28 99.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ53857.1 - 5.8e-30 104.5 0.0 3.7e-22 78.9 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain APH PF01636.23 KXZ53857.1 - 4.9e-05 23.4 0.7 0.00017 21.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ53857.1 - 0.0029 16.4 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ53857.1 - 0.19 11.1 0.1 0.35 10.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S15 PF02129.18 KXZ53858.1 - 2e-11 44.0 0.0 2.2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KXZ53858.1 - 1.7e-09 37.3 0.1 2.1e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ53858.1 - 7.7e-08 33.2 2.5 9.2e-08 32.9 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ53858.1 - 0.00011 21.9 0.1 0.00017 21.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KXZ53858.1 - 0.00019 20.2 0.2 0.004 15.9 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) DUF1100 PF06500.11 KXZ53858.1 - 0.0014 17.5 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KXZ53858.1 - 0.0031 17.0 0.2 0.0053 16.3 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXZ53858.1 - 0.082 12.5 0.3 0.2 11.2 0.3 1.4 1 1 0 1 1 1 0 Putative esterase DnaJ PF00226.31 KXZ53859.1 - 7.1e-09 35.7 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain CLAMP PF14769.6 KXZ53860.1 - 1.7e-31 108.6 0.7 1.7e-31 108.6 0.7 1.6 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 DNA_topoisoIV PF00521.20 KXZ53860.1 - 0.14 11.0 1.7 0.19 10.5 1.7 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Spore_III_AF PF09581.10 KXZ53860.1 - 1.5 8.8 5.0 2.2 8.3 5.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Peptidase_S46 PF10459.9 KXZ53860.1 - 4.5 5.8 6.9 5.8 5.4 6.9 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF896 PF05979.12 KXZ53860.1 - 6.9 6.6 7.0 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Ldh_1_N PF00056.23 KXZ53861.1 - 4.1e-45 153.3 0.1 5.8e-45 152.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXZ53861.1 - 1.4e-43 148.7 0.0 2.3e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KXZ53861.1 - 0.051 12.6 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_S9 PF00326.21 KXZ53862.1 - 1.1e-44 152.4 0.0 4.7e-44 150.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KXZ53862.1 - 4.8e-08 32.8 0.0 1e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KXZ53862.1 - 2.3e-05 24.4 0.1 5.6e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KXZ53862.1 - 0.00011 21.8 2.9 0.00037 20.1 2.9 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KXZ53862.1 - 0.0014 18.0 0.3 0.72 9.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 KXZ53862.1 - 0.0019 18.0 11.5 0.032 14.2 0.6 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat AXE1 PF05448.12 KXZ53862.1 - 0.0066 15.2 0.2 0.043 12.5 0.1 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 KXZ53862.1 - 0.021 15.0 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DHHC PF01529.20 KXZ53863.1 - 2e-29 102.4 0.1 4.3e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Amino_oxidase PF01593.24 KXZ53863.1 - 1.1e-17 64.4 0.0 2.5e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ53863.1 - 2e-12 47.1 0.8 9.9e-12 44.9 0.7 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ53863.1 - 2.8e-05 23.4 2.2 0.00015 21.0 0.8 2.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXZ53863.1 - 0.00013 21.3 0.3 0.00023 20.5 0.3 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXZ53863.1 - 0.00024 20.8 8.0 0.0011 18.6 6.2 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ53863.1 - 0.00024 20.4 0.3 0.00058 19.2 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ53863.1 - 0.00079 18.9 2.6 0.0021 17.5 2.6 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXZ53863.1 - 0.0053 16.0 0.1 0.0088 15.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXZ53863.1 - 0.0054 15.6 0.0 0.0076 15.1 0.0 1.2 1 0 0 1 1 1 1 MCRA family FAD_binding_3 PF01494.19 KXZ53863.1 - 0.008 15.5 0.8 0.014 14.7 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 KXZ53863.1 - 0.077 12.4 0.6 10 5.4 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase HI0933_like PF03486.14 KXZ53863.1 - 0.12 11.0 1.5 0.18 10.5 1.5 1.2 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.18 KXZ53863.1 - 0.18 10.3 0.2 4.8 5.6 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_9 PF13454.6 KXZ53863.1 - 0.27 11.2 1.5 0.32 11.0 0.2 1.9 2 0 0 2 2 1 0 FAD-NAD(P)-binding STI1 PF17830.1 KXZ53863.1 - 0.31 11.0 0.8 3.3 7.7 0.1 2.6 3 0 0 3 3 3 0 STI1 domain adh_short PF00106.25 KXZ53863.1 - 3.9 6.9 4.7 2.7 7.4 0.6 2.2 2 0 0 2 2 2 0 short chain dehydrogenase DUF938 PF06080.12 KXZ53864.1 - 3.1e-55 187.1 0.0 9.9e-55 185.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KXZ53864.1 - 0.00012 22.7 0.0 0.095 13.4 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ53864.1 - 0.0031 17.4 0.0 0.0056 16.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ53864.1 - 0.015 16.0 0.0 0.053 14.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ53864.1 - 0.042 14.5 0.0 1.9 9.2 0.0 2.4 1 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KXZ53864.1 - 0.18 11.4 0.0 9.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Ysc84 PF04366.12 KXZ53866.1 - 1.6e-19 69.9 0.6 1.2e-18 67.1 0.6 2.3 1 1 0 1 1 1 1 Las17-binding protein actin regulator Dzip-like_N PF13815.6 KXZ53867.1 - 4.4e-25 87.9 1.6 1.6e-11 44.2 0.0 2.9 3 0 0 3 3 3 2 Iguana/Dzip1-like DAZ-interacting protein N-terminal CaMKII_AD PF08332.10 KXZ53868.1 - 2.3e-38 131.2 0.0 3.5e-38 130.6 0.0 1.3 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 KXZ53868.1 - 4.8e-11 43.0 0.0 7.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KXZ53868.1 - 1.3e-09 38.3 0.4 5.5e-09 36.3 0.4 1.8 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KXZ53868.1 - 0.058 14.0 0.2 0.31 11.7 0.2 1.9 1 1 0 1 1 1 0 SnoaL-like domain Complex1_30kDa PF00329.19 KXZ53869.1 - 1.6e-44 151.4 0.1 2.5e-44 150.8 0.1 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HMG_CoA_synt_N PF01154.17 KXZ53869.1 - 0.0099 15.8 0.1 5.9 6.7 0.0 2.3 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal VASt PF16016.5 KXZ53870.1 - 7.9e-05 23.1 0.0 0.00012 22.6 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DASH_Dad2 PF08654.10 KXZ53870.1 - 0.053 13.9 0.4 0.099 13.1 0.4 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 FAST_1 PF06743.15 KXZ53871.1 - 0.00015 21.6 1.4 2.5 8.1 0.1 4.4 3 2 2 5 5 5 3 FAST kinase-like protein, subdomain 1 DnaJ PF00226.31 KXZ53872.1 - 3.2e-15 56.0 0.0 5.4e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Trypan_PARP PF05887.11 KXZ53872.1 - 0.0064 16.5 0.5 0.0064 16.5 0.5 2.2 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Thioredoxin PF00085.20 KXZ53874.1 - 7.8e-27 93.3 0.0 8e-21 74.0 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KXZ53874.1 - 4e-10 39.9 0.0 0.00023 21.1 0.0 4.8 5 1 0 5 5 5 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXZ53874.1 - 9.7e-08 31.7 0.0 0.0011 18.3 0.0 3.5 4 0 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXZ53874.1 - 9.2e-07 29.3 0.0 0.0039 17.6 0.0 3.8 3 2 0 3 3 3 2 Thioredoxin-like domain Mto2_bdg PF12808.7 KXZ53874.1 - 0.00038 20.7 0.9 0.00087 19.5 0.9 1.6 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Thioredoxin_8 PF13905.6 KXZ53874.1 - 0.0014 18.9 0.0 8.1 6.8 0.0 3.9 4 1 1 5 5 5 2 Thioredoxin-like TraF PF13728.6 KXZ53874.1 - 0.025 14.4 0.0 0.94 9.3 0.0 2.7 3 0 0 3 3 3 0 F plasmid transfer operon protein DUF3886 PF13025.6 KXZ53874.1 - 2.4 8.4 8.8 5.4 7.3 8.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Metallophos PF00149.28 KXZ53876.1 - 3.4e-31 109.3 0.1 5.1e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KXZ53876.1 - 5.9e-26 90.6 0.2 1.6e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 KXZ53876.1 - 4.6e-16 57.9 10.9 3.9e-06 26.5 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ53876.1 - 4.3e-14 51.4 12.3 1.2e-05 25.0 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ53876.1 - 6.4e-12 45.0 8.9 0.00031 20.4 0.0 3.5 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 KXZ53876.1 - 4.6e-11 42.0 3.0 0.00099 19.1 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ53876.1 - 1.2e-09 37.9 3.3 6.1e-05 23.1 0.9 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ53876.1 - 4.3e-09 36.4 0.7 0.00078 19.5 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ53876.1 - 5.4e-07 30.2 7.4 0.00055 20.5 1.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ53876.1 - 2.8e-06 27.7 3.8 0.0022 18.7 0.3 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ53876.1 - 3.3e-05 24.3 3.8 0.00039 20.9 0.6 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ53876.1 - 0.00018 21.7 0.9 0.56 10.5 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat EFP_N PF08207.12 KXZ53876.1 - 0.084 12.9 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain ANAPC3 PF12895.7 KXZ53876.1 - 0.099 12.9 3.7 0.21 11.8 1.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.12 KXZ53876.1 - 0.13 12.3 1.2 0.25 11.4 0.2 2.0 3 0 0 3 3 2 0 Protein of unknown function (DUF627) Methyltransf_23 PF13489.6 KXZ53877.1 - 7.7e-17 61.6 0.0 4e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ53877.1 - 2.4e-16 60.1 0.1 4.4e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ53877.1 - 1.2e-15 58.0 0.1 2.1e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ53877.1 - 7.5e-15 55.4 0.1 1.5e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ53877.1 - 5.5e-13 49.0 0.0 8.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXZ53877.1 - 2e-07 30.7 0.1 2.9e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KXZ53877.1 - 2.1e-06 27.5 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 KXZ53877.1 - 3.1e-06 26.7 0.0 4.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXZ53877.1 - 3.1e-05 23.6 0.0 4.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXZ53877.1 - 6.7e-05 22.6 0.1 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KXZ53877.1 - 0.00017 21.6 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KXZ53877.1 - 0.002 17.3 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_9 PF08003.11 KXZ53877.1 - 0.0031 16.5 0.0 0.0046 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 KXZ53877.1 - 0.015 15.1 0.0 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_15 PF09445.10 KXZ53877.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.14 KXZ53877.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.11 KXZ53877.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 KXZ53877.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KXZ53877.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SRR1 PF07985.12 KXZ53878.1 - 5.8e-12 45.5 0.2 9.3e-12 44.8 0.2 1.3 1 0 0 1 1 1 1 SRR1 Beta_elim_lyase PF01212.21 KXZ53879.1 - 1.7e-89 300.0 0.0 2.3e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KXZ53879.1 - 0.0019 17.0 0.0 0.0026 16.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_3 PF00202.21 KXZ53879.1 - 0.053 12.2 0.0 0.56 8.8 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 KXZ53879.1 - 0.13 11.5 0.0 2.3 7.5 0.0 2.6 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Heme_oxygenase PF01126.20 KXZ53880.1 - 1.1e-08 35.1 0.1 1.5e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Heme oxygenase Flavoprotein PF02441.19 KXZ53881.1 - 2.2e-32 112.0 0.0 2.8e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Dus PF01207.17 KXZ53882.1 - 3.2e-53 180.8 0.0 4.3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.6 KXZ53882.1 - 0.0046 16.4 0.1 0.0072 15.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Hep_59 PF07052.11 KXZ53883.1 - 7.1e-12 46.0 0.0 3.1e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 TCR PF03638.15 KXZ53884.1 - 5.5e-24 84.2 50.2 7.7e-12 45.3 21.0 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KXZ53884.1 - 0.53 10.4 41.1 0.21 11.7 16.7 2.5 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 DUF2167 PF09935.9 KXZ53887.1 - 0.15 11.3 0.3 33 3.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2167) CSN7a_helixI PF18392.1 KXZ53888.1 - 0.0043 16.9 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain Cu-oxidase_2 PF07731.14 KXZ53889.1 - 6.6e-32 110.1 0.2 1.1e-13 51.1 0.0 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXZ53889.1 - 2e-22 79.4 0.1 1.3e-19 70.4 0.0 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KXZ53889.1 - 3.6e-18 66.2 0.0 4.5e-17 62.6 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase WD40 PF00400.32 KXZ53891.1 - 5.7e-16 58.6 12.5 7.4e-07 29.8 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ53891.1 - 6.9e-08 32.7 0.0 0.016 15.5 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ53891.1 - 0.19 10.7 0.0 0.4 9.6 0.0 1.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3337 PF11816.8 KXZ53892.1 - 1.8e-11 44.2 0.0 2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) Glyco_transf_90 PF05686.12 KXZ53893.1 - 5.3e-15 55.2 0.2 2.2e-14 53.2 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 90 DUF4646 PF15496.6 KXZ53893.1 - 0.062 13.9 0.0 0.17 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) Tmemb_161AB PF10268.9 KXZ53894.1 - 0.018 13.7 0.0 0.042 12.5 0.0 1.6 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Helitron_like_N PF14214.6 KXZ53896.1 - 3.3e-06 27.5 0.0 6.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus ENT PF03735.14 KXZ53897.1 - 4.1e-05 23.6 0.0 8.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ENT domain Thioredoxin PF00085.20 KXZ53899.1 - 5.2e-58 193.4 0.1 2.4e-30 104.6 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KXZ53899.1 - 6.1e-08 32.8 0.0 0.0093 15.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KXZ53899.1 - 1.1e-06 29.0 0.5 0.17 12.4 0.0 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KXZ53899.1 - 1.6e-05 25.0 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 KXZ53899.1 - 4.8e-05 23.3 0.1 0.24 11.5 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_8 PF13905.6 KXZ53899.1 - 0.0044 17.3 0.0 38 4.7 0.0 4.1 3 2 2 5 5 5 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KXZ53899.1 - 0.028 14.2 0.0 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin AhpC-TSA PF00578.21 KXZ53899.1 - 0.031 14.2 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA family OST3_OST6 PF04756.13 KXZ53899.1 - 0.064 12.6 0.0 8.9 5.6 0.0 2.3 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Serglycin PF04360.12 KXZ53899.1 - 0.11 12.4 3.8 0.22 11.5 3.8 1.5 1 0 0 1 1 1 0 Serglycin Glutaredoxin PF00462.24 KXZ53899.1 - 0.61 10.3 1.9 29 5.0 0.2 2.7 2 1 0 2 2 2 0 Glutaredoxin IATP PF04568.12 KXZ53899.1 - 3.4 8.2 6.9 79 3.8 0.0 2.7 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP NuA4 PF09340.10 KXZ53900.1 - 1.6e-19 69.5 0.2 2.2e-19 69.1 0.2 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 FlxA PF14282.6 KXZ53900.1 - 0.048 13.7 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 FlxA-like protein RRM_1 PF00076.22 KXZ53901.1 - 1.2e-08 34.6 0.0 8.2e-08 32.0 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KXZ53901.1 - 5.6e-06 25.6 3.5 8.9e-06 24.9 3.5 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_7 PF16367.5 KXZ53901.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Keratin_2_head PF16208.5 KXZ53901.1 - 0.052 13.7 35.2 0.12 12.5 35.2 1.6 1 0 0 1 1 1 0 Keratin type II head MORN PF02493.20 KXZ53902.1 - 2.2e-31 105.9 38.3 6.2e-06 25.8 0.9 7.0 7 0 0 7 7 7 6 MORN repeat DUF3048_C PF17479.2 KXZ53902.1 - 0.097 13.1 16.6 1.9 8.9 0.3 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain PUF PF00806.19 KXZ53903.1 - 1.2e-39 131.8 0.0 7.3e-07 28.5 0.0 7.3 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat LRR_6 PF13516.6 KXZ53904.1 - 1.9e-06 27.5 5.0 0.13 12.4 0.3 4.1 4 0 0 4 4 4 3 Leucine Rich repeat LRR_8 PF13855.6 KXZ53904.1 - 0.017 14.9 3.5 0.21 11.4 0.2 3.4 2 2 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 KXZ53904.1 - 0.037 14.5 1.0 66 4.7 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat DNA_pol3_chi PF04364.13 KXZ53904.1 - 0.077 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC LRR_4 PF12799.7 KXZ53904.1 - 0.41 11.1 5.7 4.4 7.9 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Urb2 PF10441.9 KXZ53905.1 - 2.4e-11 44.0 0.0 1.1e-09 38.5 0.0 3.3 3 1 0 3 3 3 1 Urb2/Npa2 family PsbP PF01789.16 KXZ53907.1 - 1.5e-06 28.4 0.0 5.5e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 PsbP DUF3464 PF11947.8 KXZ53908.1 - 1.3e-38 132.1 0.0 1.4e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 MFS_1 PF07690.16 KXZ53908.1 - 0.025 13.5 2.0 0.032 13.2 2.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Hydrolase_4 PF12146.8 KXZ53909.1 - 3.2e-08 33.1 0.0 2.2e-07 30.4 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ53909.1 - 0.0017 18.0 0.0 0.0036 17.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXZ53909.1 - 0.002 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KXZ53909.1 - 0.0085 15.7 0.0 4.3 6.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family EF-hand_1 PF00036.32 KXZ53910.1 - 5.7e-15 53.7 0.1 1.1e-06 27.7 0.0 2.4 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KXZ53910.1 - 9.7e-14 50.2 0.8 4e-06 26.1 0.0 2.8 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXZ53910.1 - 1.3e-12 46.5 0.1 3.5e-05 23.4 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXZ53910.1 - 2.5e-11 43.9 0.1 3.9e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ53910.1 - 3.2e-10 39.7 0.0 0.00018 21.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXZ53910.1 - 0.045 14.1 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Pan3_PK PF18101.1 KXZ53910.1 - 0.096 12.7 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Pkinase PF00069.25 KXZ53911.1 - 4e-56 190.3 0.0 4.8e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53911.1 - 4.3e-23 81.9 0.0 5.6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ53911.1 - 1.8e-06 27.5 0.0 4.9e-06 26.1 0.0 1.7 2 1 0 2 2 2 1 Kinase-like EF-hand_5 PF13202.6 KXZ53911.1 - 1.9e-05 23.9 0.0 4.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ53911.1 - 4.1e-05 22.8 0.0 9.7e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ53911.1 - 6.9e-05 22.5 0.0 0.00017 21.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXZ53911.1 - 0.0046 16.8 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KXZ53911.1 - 0.0052 17.2 0.0 0.0089 16.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair FTA2 PF13095.6 KXZ53911.1 - 0.018 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXZ53911.1 - 0.038 13.9 0.1 0.51 10.2 0.0 2.5 2 2 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXZ53911.1 - 0.094 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KXZ53911.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 KXZ53911.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KXZ53912.1 - 7e-72 242.0 0.0 1.8e-71 240.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53912.1 - 8.4e-29 100.6 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 KXZ53912.1 - 2.5e-28 95.5 1.6 4.7e-06 25.8 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ53912.1 - 2.7e-23 82.2 0.3 1.3e-11 44.8 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ53912.1 - 1.1e-22 77.9 2.6 8.8e-05 22.1 0.0 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXZ53912.1 - 5.7e-22 76.2 0.7 4.6e-05 22.7 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXZ53912.1 - 1.8e-18 66.1 3.3 9.8e-09 34.9 0.0 4.2 2 1 2 4 4 4 4 EF-hand domain pair Kinase-like PF14531.6 KXZ53912.1 - 3e-07 30.1 0.0 2.9e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 Kinase-like EF-hand_4 PF12763.7 KXZ53912.1 - 3.3e-07 30.2 0.5 0.00066 19.6 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXZ53912.1 - 8e-05 22.9 0.1 0.0029 17.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXZ53912.1 - 0.00073 19.8 0.1 0.35 11.2 0.0 2.8 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 KXZ53912.1 - 0.0036 16.7 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_14 PF17959.1 KXZ53912.1 - 0.024 15.0 0.1 14 6.1 0.0 3.1 1 1 0 2 2 2 0 EF-hand domain TcdB_toxin_midN PF12256.8 KXZ53912.1 - 0.062 12.7 0.1 1.1 8.7 0.0 2.3 1 1 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region VCBS PF13517.6 KXZ53912.1 - 0.075 13.6 0.6 16 6.2 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DHHA2 PF02833.14 KXZ53912.1 - 0.12 12.6 1.0 3.2 7.9 0.1 2.4 2 0 0 2 2 2 0 DHHA2 domain DUF982 PF06169.12 KXZ53912.1 - 0.12 12.4 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF982) APH PF01636.23 KXZ53912.1 - 0.15 11.9 0.0 2.5 8.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Dockerin_1 PF00404.18 KXZ53912.1 - 0.42 10.8 2.1 28 5.0 2.3 2.7 1 1 1 2 2 2 0 Dockerin type I domain FG-GAP PF01839.23 KXZ53912.1 - 1.2 9.4 4.3 24 5.2 0.7 2.5 2 0 0 2 2 2 0 FG-GAP repeat Pkinase PF00069.25 KXZ53913.1 - 7.5e-63 212.4 0.0 1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53913.1 - 1.5e-40 139.1 0.0 2.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ53913.1 - 3.2e-06 26.2 0.0 7.1e-06 25.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXZ53913.1 - 0.00017 21.0 0.1 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXZ53913.1 - 0.0002 21.4 0.0 0.059 13.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Arm PF00514.23 KXZ53914.1 - 1.5e-09 37.6 4.7 0.00011 22.1 0.1 4.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 KXZ53914.1 - 0.056 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 KXZ53914.1 - 0.064 13.3 0.0 0.39 10.8 0.0 2.2 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain T2SSN PF01203.19 KXZ53916.1 - 0.13 12.4 10.2 0.11 12.7 1.8 2.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein N WD40 PF00400.32 KXZ53917.1 - 2e-07 31.6 8.0 0.24 12.3 0.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.12 KXZ53917.1 - 0.0066 16.2 6.7 0.016 14.9 6.7 1.7 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Pep3_Vps18 PF05131.14 KXZ53918.1 - 3.3e-16 59.4 0.0 5.5e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family zf_C2H2_13 PF18508.1 KXZ53919.1 - 0.11 12.1 1.1 11 5.7 0.3 2.4 2 0 0 2 2 2 0 Zinc finger domain Lectin_C PF00059.21 KXZ53920.1 - 0.0006 20.5 0.0 0.001 19.8 0.0 1.4 1 1 0 1 1 1 1 Lectin C-type domain HA2 PF04408.23 KXZ53924.1 - 8.2e-20 71.1 0.0 1.7e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXZ53924.1 - 7.3e-19 67.9 0.0 1.3e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXZ53924.1 - 3.4e-11 43.5 0.0 6.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ53924.1 - 0.015 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Peptidase_S8 PF00082.22 KXZ53925.1 - 2e-30 106.1 17.1 5.5e-30 104.7 16.1 2.2 1 1 0 1 1 1 1 Subtilase family Kazal_1 PF00050.21 KXZ53925.1 - 2.3e-06 27.5 0.8 5.1e-06 26.4 0.8 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KXZ53925.1 - 2.2e-05 24.5 1.7 4.4e-05 23.5 1.7 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain PT PF04886.12 KXZ53925.1 - 0.0013 18.2 27.3 0.0013 18.2 27.3 3.9 3 1 0 3 3 3 1 PT repeat DUF3883 PF13020.6 KXZ53927.1 - 2.5e-15 56.3 0.0 4.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 KXZ53927.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase cobW PF02492.19 KXZ53928.1 - 1.1e-19 70.7 0.0 3.1e-19 69.2 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ53928.1 - 3.8e-09 36.4 0.0 0.00057 19.8 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain Glyco_transf_90 PF05686.12 KXZ53929.1 - 2.3e-17 63.0 0.2 3.2e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 MS_channel PF00924.18 KXZ53932.1 - 1.8e-17 63.6 4.1 3.3e-17 62.7 4.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Med3 PF11593.8 KXZ53932.1 - 6.7 5.8 4.8 11 5.1 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF924 PF06041.11 KXZ53935.1 - 5.5e-51 173.2 0.0 9e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) GAF PF01590.26 KXZ53935.1 - 0.0046 17.6 0.1 0.052 14.2 0.1 2.5 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.25 KXZ53936.1 - 3.5e-29 102.0 0.0 5e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53936.1 - 1.1e-06 28.1 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HSBP1 PF06825.12 KXZ53937.1 - 4.7e-20 71.2 4.4 5.5e-20 71.0 4.4 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 FtsK_SpoIIIE PF01580.18 KXZ53937.1 - 0.0019 17.6 0.1 0.002 17.5 0.1 1.0 1 0 0 1 1 1 1 FtsK/SpoIIIE family BLOC1_2 PF10046.9 KXZ53937.1 - 0.0064 16.8 0.8 0.011 16.0 0.8 1.3 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 KXZ53937.1 - 0.008 16.5 0.9 0.31 11.4 0.2 1.9 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UBX PF00789.20 KXZ53937.1 - 0.017 15.3 0.1 0.023 14.9 0.1 1.3 1 1 0 1 1 1 0 UBX domain Cullin_Nedd8 PF10557.9 KXZ53937.1 - 0.028 14.5 0.2 0.044 13.8 0.2 1.4 1 1 0 1 1 1 0 Cullin protein neddylation domain SF-assemblin PF06705.11 KXZ53937.1 - 0.056 12.8 0.4 0.067 12.5 0.4 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin BORCS6 PF10157.9 KXZ53937.1 - 0.067 13.4 0.2 0.084 13.1 0.2 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 PhoU PF01895.19 KXZ53937.1 - 0.11 13.0 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 PhoU domain A_deamin PF02137.18 KXZ53938.1 - 1.5e-32 113.3 0.0 1.7e-25 90.2 0.0 3.9 4 0 0 4 4 4 3 Adenosine-deaminase (editase) domain dsrm PF00035.26 KXZ53938.1 - 8.1e-11 42.5 0.0 3.4e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ion_trans PF00520.31 KXZ53940.1 - 3.5e-23 82.1 13.7 9e-23 80.8 13.7 1.6 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXZ53940.1 - 5e-14 52.0 5.5 5e-14 52.0 5.5 1.9 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KXZ53940.1 - 0.0022 18.0 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SelP_N PF04592.14 KXZ53940.1 - 2.8 7.3 21.9 4.4 6.6 21.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ank_2 PF12796.7 KXZ53941.1 - 3.1e-30 104.6 0.1 5.6e-11 42.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ53941.1 - 2.2e-27 94.2 1.1 7.8e-05 23.0 0.2 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KXZ53941.1 - 2.6e-24 82.6 1.4 0.00018 21.6 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KXZ53941.1 - 3.8e-24 84.7 0.2 4.8e-08 33.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ53941.1 - 5.4e-19 68.0 4.0 0.00011 22.5 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Folate_rec PF03024.14 KXZ53941.1 - 0.01 15.7 0.9 0.033 14.0 1.3 1.5 2 0 0 2 2 2 0 Folate receptor family STT3 PF02516.14 KXZ53944.1 - 3.1e-106 356.2 31.1 1.5e-105 353.9 31.1 1.8 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Herpes_capsid PF06112.11 KXZ53945.1 - 7.6 6.6 7.5 5.4 7.0 4.0 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF3391 PF11871.8 KXZ53945.1 - 8.9 6.9 6.6 5.4 7.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Radial_spoke PF04712.12 KXZ53946.1 - 3.1e-08 33.0 0.7 0.0024 16.9 0.2 2.7 2 1 1 3 3 3 2 Radial spokehead-like protein PSI_PsaH PF03244.14 KXZ53947.1 - 5.6e-23 81.0 0.1 6.2e-23 80.8 0.1 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit VI RRM_1 PF00076.22 KXZ53948.1 - 3.2e-34 116.6 0.4 6.9e-16 57.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ53948.1 - 6.4e-14 51.9 0.2 1.4e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 KXZ53948.1 - 0.16 12.2 5.5 6.5 7.0 0.2 3.3 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter tRNA-synt_His PF13393.6 KXZ53948.1 - 0.3 10.3 2.6 0.47 9.7 2.6 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase RRM_3 PF08777.11 KXZ53948.1 - 0.3 11.2 3.1 0.57 10.3 0.0 2.4 2 1 1 3 3 3 0 RNA binding motif Ion_trans PF00520.31 KXZ53950.1 - 6.8e-35 120.5 2.6 9.4e-35 120.0 2.6 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KXZ53950.1 - 1.8e-12 47.0 0.4 1.8e-12 47.0 0.4 1.9 2 0 0 2 2 2 1 Ion channel BPS PF08947.10 KXZ53950.1 - 0.012 15.4 0.2 0.027 14.3 0.2 1.6 1 0 0 1 1 1 0 BPS (Between PH and SH2) SpoVS PF04232.12 KXZ53951.1 - 3.6e-15 55.5 9.2 2.9e-09 36.5 0.5 2.8 2 1 0 2 2 2 2 Stage V sporulation protein S (SpoVS) TPR_11 PF13414.6 KXZ53952.1 - 0.081 12.6 7.2 12 5.7 0.0 4.8 6 0 0 6 6 6 0 TPR repeat CFAP91 PF14738.6 KXZ53953.1 - 6.9e-48 162.6 8.9 6.9e-48 162.6 8.9 1.8 2 0 0 2 2 2 1 Cilia- and flagella-associated protein 91 IQ PF00612.27 KXZ53953.1 - 1.7e-10 39.8 15.9 0.0015 18.1 1.6 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif Trypan_PARP PF05887.11 KXZ53953.1 - 0.0011 19.0 48.9 0.0011 19.0 48.9 7.2 2 2 5 7 7 7 2 Procyclic acidic repetitive protein (PARP) TPT PF03151.16 KXZ53955.1 - 1.6e-28 99.9 14.9 2e-28 99.6 14.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ53955.1 - 2.2e-10 40.9 28.9 1.2e-05 25.5 12.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXZ53955.1 - 3e-06 26.7 16.2 6e-06 25.7 16.2 1.5 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KXZ53955.1 - 0.048 12.9 16.5 0.082 12.1 16.5 1.4 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport TMEM234 PF10639.9 KXZ53955.1 - 0.64 10.1 8.0 3.2 7.8 4.4 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 PI31_Prot_C PF08577.11 KXZ53956.1 - 7.6e-08 33.4 18.8 7.6e-08 33.4 18.8 2.2 2 0 0 2 2 2 1 PI31 proteasome regulator PI31_Prot_N PF11566.8 KXZ53956.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal Auts2 PF15336.6 KXZ53956.1 - 9.8 6.2 7.9 22 5.1 7.9 1.5 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Clat_adaptor_s PF01217.20 KXZ53957.1 - 3.2e-41 140.6 2.3 3.5e-41 140.4 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 KXZ53957.1 - 0.018 15.0 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Bromodomain PF00439.25 KXZ53958.1 - 2.3e-08 34.0 0.0 4.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain MoaF_C PF17409.2 KXZ53958.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 MoaF C-terminal domain Ank_2 PF12796.7 KXZ53959.1 - 1e-32 112.5 14.6 1.6e-11 44.6 1.9 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ53959.1 - 1.6e-25 86.3 7.8 0.0012 19.1 0.1 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KXZ53959.1 - 6.6e-21 74.4 8.8 9.5e-06 26.1 0.2 6.4 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ53959.1 - 6e-20 70.7 21.1 0.0062 16.9 0.1 8.5 8 1 1 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KXZ53959.1 - 1.3e-19 70.0 17.5 3.4e-05 24.1 0.3 7.7 1 1 7 8 8 8 6 Ankyrin repeats (many copies) HET PF06985.11 KXZ53959.1 - 0.00022 21.6 0.1 0.00022 21.6 0.1 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SnoaL_2 PF12680.7 KXZ53960.1 - 1e-05 26.1 0.0 1.2e-05 25.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXZ53960.1 - 0.083 13.3 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Acetyltransf_1 PF00583.25 KXZ53962.1 - 4.7e-14 52.6 0.0 6.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ53962.1 - 5.3e-10 39.3 0.0 8.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ53962.1 - 5.6e-08 33.1 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ53962.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXZ53962.1 - 0.042 14.0 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KXZ53962.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase RNA_pol_inhib PF16857.5 KXZ53962.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase inhibitor DUF1543 PF07566.12 KXZ53962.1 - 0.19 11.5 0.1 3.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) PanZ PF12568.8 KXZ53962.1 - 0.46 10.2 2.0 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ CLP_protease PF00574.23 KXZ53963.1 - 5.1e-30 104.7 0.0 8e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Clp protease Aminotran_5 PF00266.19 KXZ53964.1 - 3.9e-55 187.3 0.0 4.5e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V PH_12 PF16457.5 KXZ53964.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Thioredox_DsbH PF03190.15 KXZ53965.1 - 1.2e-74 249.7 0.0 2.4e-74 248.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KXZ53965.1 - 6e-11 42.4 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_76 PF03663.14 KXZ53965.1 - 0.12 11.8 1.3 2.2 7.7 0.0 2.4 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 Thioredoxin_2 PF13098.6 KXZ53965.1 - 0.17 12.4 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain NolB PF17398.2 KXZ53965.1 - 3.1 8.2 4.9 6 7.2 0.0 3.1 2 1 1 3 3 3 0 Nodulation protein NolB DUF4371 PF14291.6 KXZ53966.1 - 7e-11 42.2 0.2 1.2e-10 41.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KXZ53966.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) RicinB_lectin_2 PF14200.6 KXZ53968.1 - 3.8e-118 386.5 59.8 3.3e-08 34.1 0.0 23.3 12 9 16 28 28 28 27 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ53968.1 - 1.4e-94 313.0 60.3 1.4e-10 41.5 1.9 14.9 10 6 5 15 15 15 14 Ricin-type beta-trefoil lectin domain Glyco_hydro_9 PF00759.19 KXZ53968.1 - 8.2e-48 163.8 0.7 1.3e-47 163.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Pilin_PilX PF11530.8 KXZ53968.1 - 0.022 14.7 0.0 28 4.7 0.0 4.4 5 0 0 5 5 5 0 Minor type IV pilin, PilX BetaGal_dom3 PF13363.6 KXZ53968.1 - 0.044 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 MCU PF04678.13 KXZ53970.1 - 0.18 11.9 1.0 0.21 11.7 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter BACK PF07707.15 KXZ53971.1 - 1.3e-05 25.2 0.0 3.4e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ53971.1 - 0.00082 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Na_H_Exchanger PF00999.21 KXZ53972.1 - 4.3e-56 190.3 45.0 4.3e-56 190.3 45.0 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 KXZ53972.1 - 1.4e-18 67.3 0.1 1.4e-18 67.3 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KXZ53972.1 - 0.1 12.1 1.5 0.24 10.9 0.1 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SlyX PF04102.12 KXZ53972.1 - 5.3 7.7 9.3 8.9 7.0 1.4 3.3 2 1 1 3 3 3 0 SlyX GAS PF13851.6 KXZ53972.1 - 8.2 5.7 11.8 2 7.7 5.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Senescence PF06911.12 KXZ53973.1 - 0.00017 22.0 0.4 0.018 15.4 0.1 2.5 2 0 0 2 2 2 2 Senescence-associated protein BTB PF00651.31 KXZ53975.1 - 6.3e-16 58.6 0.0 1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain SGL PF08450.12 KXZ53975.1 - 0.059 12.9 0.2 0.092 12.3 0.2 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Nucleotid_trans PF03407.16 KXZ53977.1 - 1.2e-11 45.0 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Epimerase PF01370.21 KXZ53978.1 - 1.1e-42 146.2 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ53978.1 - 6.2e-42 144.2 0.0 8.1e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXZ53978.1 - 1.5e-10 40.6 0.0 1.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXZ53978.1 - 5.7e-08 32.2 0.0 4.8e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXZ53978.1 - 1.5e-05 24.1 0.0 1.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXZ53978.1 - 0.0034 17.3 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXZ53978.1 - 0.11 12.0 1.4 2.9 7.3 0.3 2.6 2 1 0 2 2 2 0 short chain dehydrogenase UbiA PF01040.18 KXZ53979.1 - 1.4e-21 77.0 31.0 5e-21 75.2 30.9 1.8 1 1 0 1 1 1 1 UbiA prenyltransferase family EcKinase PF02958.20 KXZ53981.1 - 1.6e-10 40.8 0.0 3.1e-10 39.9 0.0 1.4 2 0 0 2 2 2 1 Ecdysteroid kinase APH PF01636.23 KXZ53981.1 - 6.4e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXZ53981.1 - 3.3e-05 22.9 0.0 4.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KXZ53981.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M24_C PF16188.5 KXZ53981.1 - 0.027 14.5 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 Pkinase PF00069.25 KXZ53981.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain ABC_transp_aux PF09822.9 KXZ53982.1 - 1.4e-07 31.3 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 KXZ53982.1 - 0.0012 17.8 0.0 0.041 12.7 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF676 PF05057.14 KXZ53983.1 - 4.8e-33 114.5 0.0 3.1e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXZ53983.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 KXZ53983.1 - 0.0026 17.3 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Palm_thioest PF02089.15 KXZ53983.1 - 0.0037 17.1 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KXZ53983.1 - 0.036 13.3 0.5 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KXZ53983.1 - 0.042 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 KXZ53983.1 - 0.24 10.5 0.0 0.34 10.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase BACK PF07707.15 KXZ53984.1 - 3.9e-06 26.9 0.0 9.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ53984.1 - 0.22 11.7 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DUF3707 PF12499.8 KXZ53985.1 - 2e-17 64.1 19.2 3.3e-15 56.9 10.1 3.4 3 0 0 3 3 3 3 Pherophorin BBS2_C PF14782.6 KXZ53986.1 - 6.8e-148 493.0 0.0 9.9e-147 489.2 0.0 2.4 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KXZ53986.1 - 3.5e-39 133.2 0.0 1e-37 128.4 0.0 2.5 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 KXZ53986.1 - 4.4e-06 27.2 1.2 0.11 13.1 0.1 3.5 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 KXZ53986.1 - 5e-06 25.8 0.2 0.35 9.8 0.1 3.2 1 1 2 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 KXZ53986.1 - 1.2e-05 25.3 1.7 0.068 13.3 0.0 3.0 2 0 0 2 2 2 2 FG-GAP repeat Mu-like_Pro PF10123.9 KXZ53986.1 - 10 5.6 10.0 0.26 10.8 2.5 2.1 3 0 0 3 3 3 0 Mu-like prophage I protein ATP-synt_C PF00137.21 KXZ53987.1 - 4.2e-08 33.4 11.6 4.2e-08 33.4 11.6 2.7 2 1 1 3 3 3 1 ATP synthase subunit C STAG PF08514.11 KXZ53988.1 - 2.7e-16 59.5 0.4 2.7e-16 59.5 0.4 2.3 2 1 0 2 2 2 1 STAG domain Cnd1 PF12717.7 KXZ53988.1 - 0.0057 16.7 0.0 0.98 9.4 0.0 2.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF677 PF05055.12 KXZ53988.1 - 0.086 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Transthyretin PF00576.21 KXZ53990.1 - 3.2e-33 114.7 0.0 5.4e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 HIUase/Transthyretin family OHCU_decarbox PF09349.10 KXZ53990.1 - 6.2e-32 111.2 0.0 1e-31 110.5 0.0 1.3 1 0 0 1 1 1 1 OHCU decarboxylase Occludin_ELL PF07303.13 KXZ53991.1 - 2.8e-06 28.0 4.2 4.8e-06 27.2 3.2 1.9 1 1 1 2 2 2 1 Occludin homology domain Lipoprotein_Ltp PF07553.11 KXZ53991.1 - 0.026 14.8 0.3 0.044 14.0 0.3 1.4 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein TSKS PF15358.6 KXZ53993.1 - 0.18 10.1 9.1 0.011 14.2 3.1 1.9 2 0 0 2 2 2 0 Testis-specific serine kinase substrate zf-C4H2 PF10146.9 KXZ53993.1 - 0.19 12.1 5.9 1.4 9.2 0.4 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein GIT_CC PF16559.5 KXZ53993.1 - 0.76 9.7 3.6 4.1 7.3 3.6 2.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Leu_zip PF15294.6 KXZ53993.1 - 0.93 9.0 11.3 3.2 7.2 0.2 2.2 2 0 0 2 2 2 0 Leucine zipper FlaC_arch PF05377.11 KXZ53993.1 - 2.6 8.5 7.1 6 7.3 0.1 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 KXZ53993.1 - 2.7 8.1 7.1 1.7 8.8 1.6 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KXZ53993.1 - 3 7.9 4.5 5.3 7.1 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Rab5-bind PF09311.11 KXZ53993.1 - 7.7 5.8 14.9 6.1 6.1 7.7 2.2 2 0 0 2 2 2 0 Rabaptin-like protein Fez1 PF06818.15 KXZ53993.1 - 8.1 6.8 11.2 10 6.5 0.8 2.4 2 0 0 2 2 2 0 Fez1 Fibrillin_U_N PF18193.1 KXZ53994.1 - 0.011 15.9 0.1 1.2e+02 3.0 0.0 5.1 5 0 0 5 5 5 0 Fibrillin 1 unique N-terminal domain Cecropin PF00272.19 KXZ53995.1 - 0.48 10.2 11.8 1.2 8.9 0.5 3.0 3 0 0 3 3 3 0 Cecropin family Cohesin_HEAT PF12765.7 KXZ53995.1 - 4.6 7.7 8.5 1.3e+02 3.1 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion WSC PF01822.19 KXZ53996.1 - 5.3e-08 32.9 0.1 8.5e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 WSC domain EF-hand_6 PF13405.6 KXZ53997.1 - 5.3e-05 22.8 0.1 0.00015 21.5 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KXZ53997.1 - 0.00014 21.1 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXZ53997.1 - 0.00016 22.1 0.0 0.00035 21.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ53997.1 - 0.0079 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ53997.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair ATP-synt_C PF00137.21 KXZ53998.1 - 4.2e-08 33.4 11.6 4.2e-08 33.4 11.6 2.3 2 1 1 3 3 3 1 ATP synthase subunit C Pkinase PF00069.25 KXZ53999.1 - 3.1e-54 184.1 0.0 4.3e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ53999.1 - 5.5e-34 117.6 0.0 9.6e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ53999.1 - 1.3e-06 28.6 9.1 0.00024 21.1 0.1 3.6 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ53999.1 - 2e-06 27.3 0.0 4e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ53999.1 - 1.5e-05 24.0 0.2 0.00012 21.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXZ53999.1 - 0.011 15.1 0.1 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fer2 PF00111.27 KXZ54000.1 - 0.018 15.0 0.1 0.052 13.5 0.1 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Pectate_lyase_3 PF12708.7 KXZ54001.1 - 3.5e-05 23.7 6.9 0.00046 20.1 0.3 2.8 1 1 1 3 3 3 2 Pectate lyase superfamily protein TTL PF03133.15 KXZ54003.1 - 1.1e-96 323.5 0.0 1.5e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ54003.1 - 1.6e-07 30.8 0.2 0.00016 21.1 0.0 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ54003.1 - 0.0018 17.6 0.0 0.029 13.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Tim44 PF04280.15 KXZ54004.1 - 3.5e-15 56.4 0.0 1.4e-14 54.4 0.0 1.9 1 1 0 1 1 1 1 Tim44-like domain Sugar_tr PF00083.24 KXZ54006.1 - 1.1e-29 103.6 25.3 2.6e-28 99.1 25.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXZ54006.1 - 4e-22 78.6 42.9 4e-14 52.3 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2374 PF09574.10 KXZ54006.1 - 0.98 9.3 3.9 1.9 8.4 2.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (Duf2374) Methyltransf_25 PF13649.6 KXZ54007.1 - 1.1e-05 26.0 0.0 1.5e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ54007.1 - 0.00035 21.2 0.0 0.00053 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ54007.1 - 0.0017 19.0 0.0 0.0025 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXZ54007.1 - 0.091 13.8 0.0 0.14 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 KXZ54008.1 - 2.1e-09 37.8 0.0 3.6e-05 24.3 0.2 4.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54008.1 - 1.3e-07 32.0 6.5 0.00055 20.5 0.8 5.5 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54008.1 - 3.7e-05 23.8 3.1 17 6.3 0.2 7.0 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ54008.1 - 8.3e-05 22.8 3.8 0.59 10.5 0.2 5.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) DUF434 PF04256.12 KXZ54008.1 - 0.12 12.0 0.4 0.86 9.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF434) DUF4588 PF15251.6 KXZ54009.1 - 0.13 12.0 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) MFS_1 PF07690.16 KXZ54010.1 - 5.4e-09 35.4 9.7 5.4e-09 35.4 9.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 KXZ54011.1 - 1.3e-32 113.1 0.0 6.1e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ54011.1 - 4.6e-16 59.0 0.0 3.3e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KXZ54011.1 - 0.003 17.5 1.1 0.0073 16.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ54011.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.31 KXZ54012.1 - 0.00012 22.2 0.2 0.00021 21.3 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Glycos_transf_2 PF00535.26 KXZ54013.1 - 0.014 15.2 0.0 0.048 13.5 0.0 1.7 1 1 1 2 2 2 0 Glycosyl transferase family 2 DUF1582 PF07621.11 KXZ54013.1 - 0.043 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) LEA_3 PF03242.13 KXZ54013.1 - 0.13 13.0 0.3 3.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein Guanylate_cyc PF00211.20 KXZ54014.1 - 1.4e-53 181.2 0.0 2.1e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Actin PF00022.19 KXZ54015.1 - 2.8e-106 355.5 0.0 3.3e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXZ54015.1 - 9.7e-05 21.3 0.0 0.0016 17.3 0.0 2.0 2 0 0 2 2 2 2 MreB/Mbl protein SAND PF01342.21 KXZ54016.1 - 0.0021 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 SAND domain ABM PF03992.16 KXZ54017.1 - 1.4e-15 57.1 0.6 1.1e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase ACC_epsilon PF13822.6 KXZ54017.1 - 1.5 9.5 15.9 0.062 14.0 4.6 2.4 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit ABM PF03992.16 KXZ54018.1 - 3.2e-14 52.8 0.9 2.3e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase ACC_epsilon PF13822.6 KXZ54018.1 - 5.8 7.7 14.4 0.56 10.9 4.4 2.4 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit adh_short_C2 PF13561.6 KXZ54019.1 - 5.1e-48 163.7 2.7 6.6e-48 163.3 2.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ54019.1 - 3.8e-41 140.7 0.7 4.9e-41 140.3 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ54019.1 - 8.1e-08 32.4 1.7 1.5e-07 31.5 1.7 1.4 1 1 0 1 1 1 1 KR domain ABM PF03992.16 KXZ54020.1 - 7.1e-07 29.3 0.3 0.00022 21.3 0.1 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase GAS2 PF02187.17 KXZ54020.1 - 0.025 14.6 0.3 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain ABM PF03992.16 KXZ54021.1 - 6.6e-13 48.6 0.0 5.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KXZ54022.1 - 1e-09 38.3 0.1 3.4e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase PepSY_TM PF03929.16 KXZ54023.1 - 1.5 8.4 5.9 4.2 7.0 0.2 2.0 2 0 0 2 2 2 0 PepSY-associated TM region Glycolytic PF00274.19 KXZ54025.1 - 1.6e-86 290.2 0.0 1.4e-84 283.9 0.0 2.0 2 0 0 2 2 2 2 Fructose-bisphosphate aldolase class-I GDPD PF03009.17 KXZ54026.1 - 3.4e-20 72.9 0.0 6.9e-13 48.9 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KXZ54026.1 - 0.00077 19.8 0.0 0.005 17.3 0.1 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Gly_transf_sug PF04488.15 KXZ54027.1 - 1.9e-10 41.3 0.0 2.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif YqeY PF09424.10 KXZ54029.1 - 1.2e-50 171.3 7.7 1.4e-50 171.1 7.7 1.0 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.18 KXZ54029.1 - 5.4e-06 26.3 6.5 0.0029 17.5 0.9 2.6 1 1 1 2 2 2 2 GatB domain Tma16 PF11176.8 KXZ54029.1 - 0.029 14.2 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 DUF592 PF04574.13 KXZ54029.1 - 0.049 13.4 0.1 0.86 9.4 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF592) DUF2922 PF11148.8 KXZ54029.1 - 0.077 12.7 0.7 1 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) MORN PF02493.20 KXZ54030.1 - 4.7e-17 60.8 17.0 2.8e-07 30.0 1.7 4.2 4 0 0 4 4 4 3 MORN repeat Pkinase_Tyr PF07714.17 KXZ54031.1 - 1.1e-35 123.2 0.0 1.2e-31 110.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ54031.1 - 1.3e-32 113.2 0.0 4.1e-27 95.2 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ54031.1 - 0.00045 19.1 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ54031.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ54032.1 - 0.00011 21.6 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54032.1 - 0.0014 17.9 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Spt4 PF06093.13 KXZ54033.1 - 5.7e-23 80.8 0.9 7.4e-23 80.4 0.9 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Pkinase PF00069.25 KXZ54035.1 - 6.6e-05 22.4 0.0 0.0096 15.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54035.1 - 0.0042 16.4 0.1 0.0065 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-MYND PF01753.18 KXZ54036.1 - 5.3e-07 29.6 9.5 1.2e-06 28.5 9.5 1.6 1 0 0 1 1 1 1 MYND finger ABM PF03992.16 KXZ54038.1 - 0.0053 16.9 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ank_2 PF12796.7 KXZ54040.1 - 9.2e-06 26.2 0.0 2.1e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54040.1 - 6.3e-05 23.4 0.0 0.037 14.6 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) NB PF04159.13 KXZ54040.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 NB glycoprotein Ank PF00023.30 KXZ54040.1 - 0.033 14.7 0.1 25 5.6 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 KXZ54040.1 - 0.13 12.9 0.0 23 6.0 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat ABM PF03992.16 KXZ54041.1 - 4.7e-07 29.8 0.4 6.4e-07 29.4 0.4 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KXZ54042.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KXZ54043.1 - 2e-07 31.0 0.7 2.5e-07 30.7 0.7 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ank_4 PF13637.6 KXZ54044.1 - 8.8e-27 93.1 1.6 8.6e-10 39.0 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ54044.1 - 1.8e-20 72.7 5.2 1.4e-09 38.1 0.7 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ54044.1 - 8.2e-20 70.3 7.6 4.6e-05 23.7 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KXZ54044.1 - 3.3e-19 69.3 2.8 3.8e-12 46.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54044.1 - 1e-13 50.0 1.7 0.0088 16.5 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat ARGLU PF15346.6 KXZ54044.1 - 0.22 11.4 44.0 0.31 10.9 44.0 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Ribul_P_3_epim PF00834.19 KXZ54045.1 - 1e-58 198.0 0.7 6.8e-58 195.3 0.7 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KXZ54045.1 - 0.05 13.2 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Peptidase_S10 PF00450.22 KXZ54046.1 - 1e-41 143.7 0.0 1.2e-41 143.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase FAD_binding_2 PF00890.24 KXZ54046.1 - 0.85 8.6 3.5 1.2 8.1 3.5 1.1 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KXZ54046.1 - 0.98 8.4 3.3 1.3 8.0 3.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_S10 PF00450.22 KXZ54047.1 - 1.5e-14 54.3 0.0 1.7e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ank_5 PF13857.6 KXZ54048.1 - 2.7e-34 116.8 8.6 3.1e-10 40.1 0.1 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ54048.1 - 1.3e-32 112.3 5.8 2.7e-13 50.3 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54048.1 - 1.6e-27 95.5 4.4 3.6e-10 40.2 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ54048.1 - 1.8e-27 94.5 6.0 3.7e-06 27.1 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KXZ54048.1 - 4.4e-19 66.6 0.8 0.00056 20.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Phage_T7_Capsid PF05396.11 KXZ54048.1 - 0.18 12.2 0.1 15 6.0 0.0 2.4 1 1 1 2 2 2 0 Phage T7 capsid assembly protein Ank_2 PF12796.7 KXZ54049.1 - 3.9e-28 97.9 4.5 2.2e-14 53.8 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ54049.1 - 2.5e-26 90.9 10.1 1.4e-06 28.4 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KXZ54049.1 - 1.8e-23 82.3 6.5 1.7e-08 34.6 0.2 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54049.1 - 1.4e-21 74.3 4.5 9e-06 25.7 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KXZ54049.1 - 7.8e-20 71.0 3.3 1.3e-11 44.8 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) PEGA PF08308.11 KXZ54049.1 - 0.028 14.3 0.0 12 5.9 0.0 3.0 3 0 0 3 3 3 0 PEGA domain ScdA_N PF04405.14 KXZ54049.1 - 0.096 12.4 1.6 6.3 6.5 0.1 3.4 3 1 0 3 3 3 0 Domain of Unknown function (DUF542) DEAD PF00270.29 KXZ54050.1 - 2.7e-46 157.5 0.0 4.5e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase GUCT PF08152.12 KXZ54050.1 - 3.6e-28 97.7 0.0 7.7e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.31 KXZ54050.1 - 1.2e-25 90.0 0.0 2.9e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ54050.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXZ54050.1 - 0.0048 16.3 0.0 0.0048 16.3 0.0 1.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit RCC1_2 PF13540.6 KXZ54051.1 - 3.3e-29 100.1 15.2 9.5e-08 31.6 0.4 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXZ54051.1 - 6.6e-10 39.5 12.5 0.22 12.1 0.0 6.9 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat SWIB PF02201.18 KXZ54052.1 - 3.4e-51 171.0 0.5 7.4e-28 96.2 0.1 2.4 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 KXZ54052.1 - 7.7e-14 51.4 3.2 2e-13 50.0 3.2 1.8 1 0 0 1 1 1 1 DEK C terminal domain REC1 PF18501.1 KXZ54052.1 - 0.079 12.8 0.9 0.16 11.8 0.8 1.6 1 1 0 1 1 1 0 Alpha helical recognition lobe domain DUF92 PF01940.16 KXZ54053.1 - 2.9e-67 226.5 8.6 3.6e-67 226.2 8.6 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Glyco_hydro_42 PF02449.15 KXZ54054.1 - 5e-19 68.9 1.6 6.5e-19 68.5 1.6 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_14 PF01373.17 KXZ54054.1 - 0.0077 15.2 0.9 0.012 14.5 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 14 CENP-M PF11111.8 KXZ54054.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Glyco_hydro_42 PF02449.15 KXZ54055.1 - 3e-22 79.5 1.5 4e-22 79.1 1.5 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_14 PF01373.17 KXZ54055.1 - 0.0049 15.8 2.0 0.11 11.4 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 Glyco_hydro_42 PF02449.15 KXZ54056.1 - 2.2e-21 76.6 2.0 2.9e-21 76.2 2.0 1.1 1 0 0 1 1 1 1 Beta-galactosidase DpnD-PcfM PF14207.6 KXZ54056.1 - 0.045 13.6 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 DpnD/PcfM-like protein Glyco_hydro_14 PF01373.17 KXZ54056.1 - 0.051 12.5 0.2 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 14 Pkinase_Tyr PF07714.17 KXZ54057.1 - 2.1e-48 164.9 0.0 1.4e-38 132.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ54057.1 - 1.6e-36 126.0 0.0 3e-27 95.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ54057.1 - 0.0062 15.3 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ54057.1 - 0.17 11.8 0.0 0.84 9.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family AAA PF00004.29 KXZ54058.1 - 3.5e-30 105.1 0.0 5.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ54058.1 - 1.7e-07 31.6 0.1 7.4e-07 29.5 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXZ54058.1 - 3.5e-07 30.7 0.1 1e-06 29.2 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXZ54058.1 - 1.4e-05 25.6 0.0 2.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXZ54058.1 - 3.5e-05 23.5 0.3 0.052 13.1 0.1 2.3 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 KXZ54058.1 - 0.0002 21.2 0.0 0.00037 20.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KXZ54058.1 - 0.00044 20.6 0.0 0.00092 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KXZ54058.1 - 0.00047 20.2 0.0 0.0032 17.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXZ54058.1 - 0.00053 19.9 0.1 0.0044 16.9 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KXZ54058.1 - 0.0011 19.0 0.0 0.0066 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXZ54058.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KXZ54058.1 - 0.0012 18.2 0.0 0.18 11.0 0.0 2.1 1 1 1 2 2 2 1 KAP family P-loop domain AAA_28 PF13521.6 KXZ54058.1 - 0.0014 18.9 0.0 0.0057 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KXZ54058.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 1 0 1 1 1 1 Cytidylate kinase ATPase_2 PF01637.18 KXZ54058.1 - 0.0017 18.3 0.1 0.44 10.4 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_2 PF07724.14 KXZ54058.1 - 0.0019 18.4 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KXZ54058.1 - 0.002 17.4 0.1 0.0087 15.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KXZ54058.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KXZ54058.1 - 0.0071 16.5 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KXZ54058.1 - 0.01 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KXZ54058.1 - 0.013 15.0 0.0 0.098 12.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXZ54058.1 - 0.035 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KXZ54058.1 - 0.035 13.3 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KXZ54058.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXZ54058.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 KXZ54058.1 - 0.062 12.9 0.0 0.27 10.8 0.0 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 KXZ54058.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXZ54058.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_19 PF13245.6 KXZ54058.1 - 0.074 13.4 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_13 PF13166.6 KXZ54058.1 - 0.075 11.7 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXZ54058.1 - 0.089 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 KXZ54058.1 - 0.094 12.0 0.1 1.9 7.8 0.0 2.1 1 1 1 2 2 2 0 KaiC ABC_tran PF00005.27 KXZ54058.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 KXZ54058.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SRP54 PF00448.22 KXZ54058.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 KXZ54058.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KXZ54058.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 KXZ54058.1 - 0.21 10.8 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DnaJ PF00226.31 KXZ54060.1 - 2.5e-17 62.7 0.0 5.4e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain ADH_N PF08240.12 KXZ54060.1 - 2.7e-10 40.1 0.0 5.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ank_2 PF12796.7 KXZ54061.1 - 5.6e-24 84.5 0.4 6.1e-11 42.8 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54061.1 - 1e-20 71.6 0.2 0.00031 20.9 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXZ54061.1 - 6.1e-20 71.0 2.4 0.00019 21.6 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXZ54061.1 - 8.4e-19 67.1 3.7 2.7e-06 27.6 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KXZ54061.1 - 1.3e-18 67.1 5.4 1.1e-07 32.2 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.11 KXZ54061.1 - 0.03 14.7 0.2 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Metallophos PF00149.28 KXZ54062.1 - 8e-18 65.7 0.5 1.4e-17 64.9 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KXZ54062.1 - 2.9e-10 40.6 0.3 9.2e-10 39.0 0.3 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KXZ54062.1 - 6e-10 39.8 0.2 0.00026 21.8 0.0 2.9 2 0 0 2 2 2 2 Iron/zinc purple acid phosphatase-like protein C Exostosin PF03016.15 KXZ54063.1 - 1.1e-33 116.7 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Glyco_hydro_42 PF02449.15 KXZ54064.1 - 1.6e-17 63.9 4.3 3.8e-17 62.7 4.3 1.6 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_14 PF01373.17 KXZ54064.1 - 0.0027 16.7 0.0 0.006 15.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 GlcNAc PF11397.8 KXZ54065.1 - 1.8e-37 129.7 0.0 5.9e-23 81.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) T3SchapCesA PF11439.8 KXZ54066.1 - 0.058 13.5 0.3 0.18 12.0 0.1 1.8 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA O-FucT PF10250.9 KXZ54067.1 - 1.6e-11 44.5 0.0 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Guanylate_cyc PF00211.20 KXZ54068.1 - 3.7e-57 192.9 0.0 5.9e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Histone PF00125.24 KXZ54069.1 - 2.6e-53 179.9 2.2 2.9e-53 179.7 2.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ54069.1 - 0.00016 21.9 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ54069.1 - 0.00036 20.6 0.1 0.00069 19.7 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KXZ54069.1 - 0.0011 19.5 2.3 0.0014 19.2 2.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 KXZ54069.1 - 0.01 15.9 0.1 0.018 15.1 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KXZ54069.1 - 0.012 15.9 0.9 0.018 15.3 0.1 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Helicase_C PF00271.31 KXZ54071.1 - 1.3e-15 57.7 0.0 2.2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 KXZ54071.1 - 7.9e-06 25.7 6.8 7.9e-06 25.7 6.8 2.6 2 0 0 2 2 2 1 PHD-finger NOA36 PF06524.12 KXZ54071.1 - 0.56 9.5 13.8 0.9 8.8 13.8 1.2 1 0 0 1 1 1 0 NOA36 protein PHD_2 PF13831.6 KXZ54071.1 - 2.8 7.6 12.2 1.2 8.7 6.5 2.7 1 1 1 2 2 2 0 PHD-finger C5HCH PF17982.1 KXZ54071.1 - 4.1 7.6 15.9 0.49 10.6 3.9 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain SNF2_N PF00176.23 KXZ54072.1 - 2.2e-50 171.4 0.0 5.8e-27 94.3 0.1 2.8 2 1 1 3 3 3 2 SNF2 family N-terminal domain Agenet PF05641.12 KXZ54072.1 - 9.6e-17 61.2 1.1 5.7e-15 55.5 0.2 2.8 2 0 0 2 2 2 1 Agenet domain DEAD PF00270.29 KXZ54072.1 - 0.00019 21.3 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXZ54072.1 - 0.021 14.9 0.0 0.052 13.6 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PDEase_I PF00233.19 KXZ54073.1 - 6e-67 225.8 0.0 8e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pex24p PF06398.11 KXZ54073.1 - 4.7e-06 25.8 2.0 7e-06 25.3 2.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin CHASE PF03924.13 KXZ54073.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 CHASE domain LDcluster4 PF18306.1 KXZ54074.1 - 1.5e-46 157.9 2.7 1.7e-46 157.7 2.7 1.0 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 KXZ54074.1 - 0.00042 19.6 1.8 0.053 12.8 0.4 2.1 2 0 0 2 2 2 2 DNA recombination-mediator protein A Lysine_decarbox PF03641.14 KXZ54074.1 - 0.00066 19.8 0.0 0.0014 18.7 0.0 1.6 2 0 0 2 2 2 1 Possible lysine decarboxylase LSDAT_prok PF18171.1 KXZ54074.1 - 0.0052 16.0 2.5 0.5 9.6 0.2 2.2 1 1 1 2 2 2 2 SLOG in TRPM, prokaryote LD_cluster2 PF18163.1 KXZ54074.1 - 0.028 13.9 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 SLOG cluster2 Cas1_AcylT PF07779.12 KXZ54075.1 - 8.3e-93 311.9 18.7 1.5e-92 311.0 19.0 1.2 2 0 0 2 2 2 1 10 TM Acyl Transferase domain found in Cas1p HflK_N PF12221.8 KXZ54076.1 - 0.1 12.6 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial membrane protein N terminal LigT_PEase PF02834.16 KXZ54076.1 - 0.2 11.8 1.0 1.1 9.6 0.3 2.6 3 1 0 3 3 3 0 LigT like Phosphoesterase PilN_bio_d PF18222.1 KXZ54079.1 - 0.047 14.1 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain Glyco_hydro_9 PF00759.19 KXZ54080.1 - 2.4e-43 149.1 6.0 4.2e-43 148.3 6.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 RicinB_lectin_2 PF14200.6 KXZ54080.1 - 5.1e-08 33.5 6.1 0.0007 20.3 0.0 3.3 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ54080.1 - 2.7e-06 27.6 1.2 6.9e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RVT_1 PF00078.27 KXZ54080.1 - 1.7e-05 24.4 0.0 0.00029 20.4 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) KH_1 PF00013.29 KXZ54081.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 KH domain VDE PF07137.11 KXZ54082.1 - 3.2e-14 53.0 0.0 4.9e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 VDE lipocalin domain Aldo_ket_red PF00248.21 KXZ54084.1 - 2.7e-27 95.8 0.0 3.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Tim17 PF02466.19 KXZ54085.1 - 0.045 14.1 1.7 0.045 14.1 1.7 1.9 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.6 KXZ54085.1 - 0.32 11.0 10.0 1.5 8.9 3.1 2.6 2 0 0 2 2 2 0 Glycine zipper DUF3169 PF11368.8 KXZ54085.1 - 2.3 7.7 4.7 2.5 7.5 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Amino_oxidase PF01593.24 KXZ54086.1 - 3e-59 201.5 0.4 1.5e-57 195.9 0.4 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ54086.1 - 1.3e-09 38.1 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ54086.1 - 5.4e-05 22.9 0.1 0.00017 21.3 0.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXZ54086.1 - 0.00018 20.4 0.1 0.0003 19.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KXZ54086.1 - 0.0099 15.0 0.3 2.4 7.1 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXZ54086.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ54086.1 - 0.018 15.6 0.0 1.9 9.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXZ54086.1 - 0.025 14.5 0.2 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXZ54086.1 - 0.027 13.6 0.2 0.058 12.5 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KXZ54086.1 - 0.038 13.2 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KXZ54086.1 - 0.069 12.5 0.8 0.19 11.1 0.0 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase LRR_4 PF12799.7 KXZ54087.1 - 2.1e-15 56.6 15.1 7.2e-06 26.3 2.5 3.9 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXZ54087.1 - 1.3e-12 47.5 3.0 4.6e-07 29.5 0.5 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KXZ54087.1 - 1.3e-10 40.9 14.5 0.00014 21.6 3.2 3.6 3 1 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KXZ54087.1 - 0.00014 21.6 0.9 11 6.3 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KXZ54087.1 - 0.036 14.6 4.8 98 4.1 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat ATG16 PF08614.11 KXZ54088.1 - 6.4e-05 23.3 18.2 6.7e-05 23.2 6.5 2.4 2 1 0 2 2 2 2 Autophagy protein 16 (ATG16) Cyclin_C_2 PF16899.5 KXZ54088.1 - 0.11 12.9 0.2 0.26 11.7 0.2 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain DUF641 PF04859.12 KXZ54088.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) CCCAP PF15964.5 KXZ54088.1 - 0.69 8.1 11.8 0.026 12.9 4.9 1.8 2 0 0 2 2 2 0 Centrosomal colon cancer autoantigen protein family Csm1_N PF18504.1 KXZ54088.1 - 0.78 10.1 11.5 0.18 12.2 0.5 3.1 3 0 0 3 3 3 0 Csm1 N-terminal domain CENP-F_leu_zip PF10473.9 KXZ54088.1 - 3.8 7.5 15.7 2.1 8.4 6.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 KXZ54088.1 - 6.9 5.9 14.0 1.1 8.5 1.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) CENP-Q PF13094.6 KXZ54088.1 - 7 6.8 17.8 1.4 9.1 10.8 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HA PF03457.14 KXZ54089.1 - 6.4e-28 96.9 0.3 7.6e-14 51.8 0.3 2.3 2 0 0 2 2 2 2 Helicase associated domain Sporozoite_P67 PF05642.11 KXZ54089.1 - 3.8 5.5 6.4 5.5 5.0 6.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HI0933_like PF03486.14 KXZ54090.1 - 1.5e-79 267.6 0.0 4.9e-29 101.3 0.0 3.1 3 0 0 3 3 3 3 HI0933-like protein Pyr_redox_2 PF07992.14 KXZ54090.1 - 3.8e-09 36.2 0.0 5.4e-06 25.9 0.1 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ54090.1 - 7.6e-08 31.8 0.9 7.6e-08 31.8 0.9 3.0 3 1 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KXZ54090.1 - 1.9e-07 31.2 0.6 8.5e-07 29.1 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ54090.1 - 6.1e-07 29.3 8.5 7.9e-06 25.7 1.2 4.1 3 1 0 4 4 4 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXZ54090.1 - 2.1e-06 27.2 0.1 4.4e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXZ54090.1 - 2e-05 24.1 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXZ54090.1 - 6.5e-05 23.4 0.3 0.00035 21.1 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ54090.1 - 0.00012 21.6 1.9 0.00012 21.6 1.9 1.8 2 0 0 2 2 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXZ54090.1 - 0.00077 18.7 4.3 0.0015 17.7 1.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KXZ54090.1 - 0.0008 18.7 0.1 0.0022 17.3 0.1 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXZ54090.1 - 0.001 18.4 0.2 0.0086 15.4 0.3 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXZ54090.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KXZ54090.1 - 0.011 15.7 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KXZ54090.1 - 0.086 12.7 0.5 0.14 12.0 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Syja_N PF02383.18 KXZ54091.1 - 3.5e-69 233.6 0.0 4.4e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Pkinase PF00069.25 KXZ54092.1 - 1.4e-14 54.1 0.0 2.7e-09 36.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54092.1 - 8.3e-12 44.9 0.0 4.9e-08 32.6 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase DNA_pol_A PF00476.20 KXZ54093.1 - 7.5e-89 298.4 0.0 9.6e-89 298.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DUF4256 PF14066.6 KXZ54094.1 - 0.00017 21.3 0.3 3.1 7.5 0.0 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF4256) RnfC_N PF13375.6 KXZ54094.1 - 0.021 14.8 0.2 0.082 12.9 0.2 2.0 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Ank_3 PF13606.6 KXZ54095.1 - 0.0029 18.0 0.1 43 5.2 0.0 4.2 4 1 1 5 5 5 2 Ankyrin repeat WD40 PF00400.32 KXZ54096.1 - 1.8e-27 95.0 11.7 1.8e-05 25.4 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.11 KXZ54096.1 - 0.095 12.6 0.0 3.3 7.5 0.0 2.6 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Pro_CA PF00484.19 KXZ54097.1 - 1.2e-13 51.6 2.1 8.3e-12 45.7 2.1 2.1 1 1 0 1 1 1 1 Carbonic anhydrase tRNA_m1G_MT PF01746.21 KXZ54099.1 - 2.1e-14 53.7 0.0 3e-13 49.9 0.0 2.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RNA_Me_trans PF04252.13 KXZ54099.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase DUF3053 PF11254.8 KXZ54100.1 - 0.025 14.2 1.1 0.061 12.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Cytochrom_C PF00034.21 KXZ54100.1 - 0.2 12.8 1.4 32 5.7 0.0 3.7 3 1 0 3 3 3 0 Cytochrome c LTP_2 PF14368.6 KXZ54101.1 - 0.0031 17.6 3.5 0.011 15.8 3.5 2.0 1 1 0 1 1 1 1 Probable lipid transfer PrmC_N PF17827.1 KXZ54101.1 - 0.017 15.7 0.7 1.4 9.6 1.1 2.3 2 0 0 2 2 2 0 PrmC N-terminal domain OSK PF17182.4 KXZ54102.1 - 0.09 12.0 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 OSK domain PH_13 PF16652.5 KXZ54103.1 - 0.02 14.7 0.5 0.031 14.1 0.5 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF1694 PF07997.11 KXZ54103.1 - 0.12 12.4 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Prok-RING_1 PF14446.6 KXZ54104.1 - 0.005 16.7 4.2 0.005 16.7 4.2 2.4 2 2 0 2 2 2 1 Prokaryotic RING finger family 1 DnaJ_CXXCXGXG PF00684.19 KXZ54104.1 - 0.021 15.2 9.7 0.061 13.7 9.7 1.9 1 1 0 1 1 1 0 DnaJ central domain adh_short_C2 PF13561.6 KXZ54105.1 - 8.1e-52 176.1 0.1 9e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ54105.1 - 4.7e-46 156.7 0.2 5.9e-46 156.4 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ54105.1 - 9.2e-05 22.4 0.1 0.00012 22.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Ku PF02735.16 KXZ54106.1 - 6.1e-29 101.2 0.0 8.7e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 KXZ54106.1 - 3.6e-12 46.8 0.3 2.9e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KXZ54106.1 - 1.7e-05 24.4 0.6 3.2e-05 23.5 0.6 1.5 1 0 0 1 1 1 1 SAP domain Ku_N PF03731.15 KXZ54106.1 - 0.00085 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP30_Sin3_bdg PF13867.6 KXZ54106.1 - 0.11 12.9 0.2 0.84 10.0 0.0 2.7 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 PITH PF06201.13 KXZ54107.1 - 8.4e-39 133.2 0.0 9.7e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 KXZ54107.1 - 0.17 11.9 0.0 0.52 10.3 0.0 1.7 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal Pkinase PF00069.25 KXZ54108.1 - 1.9e-22 79.9 0.0 3.1e-22 79.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54108.1 - 1.1e-08 34.7 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2281 PF10047.9 KXZ54108.1 - 0.035 14.8 0.0 0.061 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Ank_4 PF13637.6 KXZ54109.1 - 2.6e-12 47.0 1.7 0.21 12.2 0.0 7.4 6 2 1 7 7 7 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ54109.1 - 4e-12 46.5 0.1 0.046 14.3 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54109.1 - 2.6e-06 27.3 5.2 1.3e+02 3.7 0.0 8.9 9 0 0 9 9 9 0 Ankyrin repeat F-box PF00646.33 KXZ54109.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 F-box domain Ank_5 PF13857.6 KXZ54109.1 - 0.012 15.9 8.0 35 4.9 0.0 6.9 6 1 2 8 8 8 0 Ankyrin repeats (many copies) FAST_1 PF06743.15 KXZ54110.1 - 2.7e-12 46.5 4.4 0.0029 17.5 0.1 5.6 3 2 3 6 6 6 5 FAST kinase-like protein, subdomain 1 FAST_1 PF06743.15 KXZ54111.1 - 1.7e-12 47.1 5.1 0.0014 18.5 0.1 5.6 3 2 3 6 6 6 5 FAST kinase-like protein, subdomain 1 TPR_11 PF13414.6 KXZ54112.1 - 8.3e-09 35.0 2.0 0.091 12.5 0.0 4.3 4 0 0 4 4 4 3 TPR repeat TOM20_plant PF06552.12 KXZ54112.1 - 4.9e-06 26.4 0.0 0.18 11.6 0.0 3.1 1 1 2 3 3 3 3 Plant specific mitochondrial import receptor subunit TOM20 TPR_17 PF13431.6 KXZ54112.1 - 0.059 13.8 0.2 24 5.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ54112.1 - 0.16 12.7 2.0 3.9 8.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 KXZ54112.1 - 0.18 11.2 1.4 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Trimer_CC PF08954.11 KXZ54113.1 - 0.027 14.0 1.4 0.21 11.1 1.4 2.7 1 0 0 1 1 1 0 Trimerisation motif DUF1515 PF07439.11 KXZ54113.1 - 0.2 11.7 10.2 0.032 14.3 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) TSC22 PF01166.18 KXZ54113.1 - 0.26 11.6 3.3 0.77 10.1 0.4 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 KXZ54113.1 - 4.8 7.2 60.7 0.026 14.6 21.0 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein MARVEL PF01284.23 KXZ54114.1 - 3.1e-05 24.0 10.6 3.1e-05 24.0 10.6 2.6 2 1 0 2 2 2 2 Membrane-associating domain Aldo_ket_red PF00248.21 KXZ54115.1 - 8.5e-40 136.8 0.0 1.3e-37 129.6 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Sod_Fe_C PF02777.18 KXZ54116.1 - 1.3e-30 105.5 0.0 2.4e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXZ54116.1 - 0.0024 18.3 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HTH_17 PF12728.7 KXZ54116.1 - 0.35 11.1 4.9 1.1e+02 3.1 0.0 4.7 4 0 0 4 4 4 0 Helix-turn-helix domain SAC3_GANP PF03399.16 KXZ54117.1 - 2e-22 79.9 0.0 1.4e-20 73.8 0.0 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXZ54117.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family DUF1970 PF09301.10 KXZ54117.1 - 0.53 10.6 10.5 8.1 6.7 7.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) Tic110 PF16940.5 KXZ54117.1 - 0.85 8.0 11.0 1.4 7.3 11.0 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter W2 PF02020.18 KXZ54118.1 - 2.1e-07 31.0 0.8 6.6e-07 29.4 0.0 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon ELFV_dehydrog PF00208.21 KXZ54119.1 - 4.9e-54 183.6 0.0 6.9e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KXZ54119.1 - 1.5e-48 164.0 0.0 3.2e-48 162.9 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KXZ54119.1 - 0.014 14.8 0.2 0.026 13.9 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 KXZ54120.1 - 2.6e-07 30.7 2.0 0.0011 19.3 0.5 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXZ54120.1 - 2.1e-06 28.1 4.7 0.0024 18.5 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXZ54120.1 - 0.016 15.5 0.1 0.32 11.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KXZ54120.1 - 0.016 15.5 0.1 0.016 15.5 0.1 1.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KXZ54120.1 - 0.057 13.4 3.5 2.3 8.3 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KXZ54120.1 - 0.069 13.3 1.6 2.7 8.2 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KXZ54120.1 - 0.12 12.2 0.2 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KXZ54120.1 - 0.21 11.5 2.3 6.1 6.9 0.0 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Pex14_N PF04695.13 KXZ54120.1 - 0.22 12.2 3.8 0.42 11.3 3.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-H2C2_2 PF13465.6 KXZ54120.1 - 0.25 11.8 0.9 10 6.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain U-box PF04564.15 KXZ54121.1 - 2.2e-18 66.2 0.1 4.5e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 U-box domain RRM_1 PF00076.22 KXZ54121.1 - 2.9e-11 43.0 0.0 2.3e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ54121.1 - 0.018 14.9 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif zf-NOSIP PF15906.5 KXZ54121.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein HEAT PF02985.22 KXZ54121.1 - 1.8 9.0 5.1 17 6.0 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat MOSC_N PF03476.16 KXZ54122.1 - 1.6e-31 108.6 0.0 2.6e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KXZ54122.1 - 1.2e-27 96.5 0.0 1.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 MOSC domain DegS PF05384.11 KXZ54124.1 - 0.025 14.1 4.5 0.035 13.6 4.5 1.1 1 0 0 1 1 1 0 Sensor protein DegS FlaC_arch PF05377.11 KXZ54124.1 - 0.2 12.1 0.2 0.32 11.4 0.2 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Methyltransf_25 PF13649.6 KXZ54125.1 - 2e-17 63.7 0.0 4.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ54125.1 - 8.6e-15 54.8 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ54125.1 - 1e-13 51.7 0.0 2.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ54125.1 - 2.5e-13 50.2 0.0 3.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ54125.1 - 1.5e-11 44.1 0.0 5.9e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXZ54125.1 - 3.9e-10 40.3 0.0 7.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXZ54125.1 - 1.1e-08 35.1 0.2 1.6e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXZ54125.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KXZ54125.1 - 0.00016 21.0 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXZ54125.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KXZ54125.1 - 0.0046 16.7 0.0 0.091 12.4 0.0 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 GCD14 PF08704.10 KXZ54125.1 - 0.046 13.4 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit E1_dh PF00676.20 KXZ54126.1 - 3.6e-39 134.5 0.3 8.7e-21 74.1 0.0 3.1 2 1 1 3 3 3 3 Dehydrogenase E1 component Cation_ATPase_C PF00689.21 KXZ54127.1 - 1.2e-37 129.4 0.0 2.6e-37 128.3 0.0 1.6 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF5379 PF17350.2 KXZ54127.1 - 0.58 10.5 5.0 2 8.7 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5379) ResIII PF04851.15 KXZ54129.1 - 0.0031 17.6 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Torsin PF06309.11 KXZ54129.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Torsin DEAD PF00270.29 KXZ54129.1 - 0.23 11.2 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Pkinase PF00069.25 KXZ54130.1 - 7.8e-22 77.9 0.0 3.9e-20 72.3 0.0 2.8 1 1 2 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54130.1 - 1e-07 31.5 0.0 6.3e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ54130.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like NPV_P10 PF05531.12 KXZ54131.1 - 0.05 14.1 0.2 5.1 7.6 0.1 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 KXZ54131.1 - 0.41 10.9 6.2 0.96 9.8 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein Atg14 PF10186.9 KXZ54131.1 - 5.3 6.0 5.4 11 5.0 5.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KXZ54131.1 - 8.1 6.5 6.4 4.4 7.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pyrophosphatase PF00719.19 KXZ54132.1 - 2.3e-56 190.0 0.0 2.7e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase INSC_LBD PF16748.5 KXZ54132.1 - 0.078 12.4 0.1 0.19 11.2 0.1 1.6 2 0 0 2 2 2 0 Inscuteable LGN-binding domain Tmemb_14 PF03647.13 KXZ54133.1 - 2.2e-24 86.0 9.2 2.5e-24 85.8 9.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KXZ54133.1 - 0.0013 19.0 2.4 0.0013 19.0 2.4 1.7 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 19 SpecificRecomb PF10136.9 KXZ54133.1 - 0.065 11.5 1.4 0.075 11.3 1.4 1.0 1 0 0 1 1 1 0 Site-specific recombinase CLTH PF10607.9 KXZ54134.1 - 1.9e-19 70.0 0.0 2.8e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KXZ54134.1 - 1.3e-14 54.4 0.0 1.9e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KXZ54134.1 - 0.015 15.2 0.2 0.039 13.9 0.1 1.8 2 0 0 2 2 2 0 LisH Guanylate_cyc PF00211.20 KXZ54135.1 - 6.5e-11 42.2 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peroxin-22 PF12827.7 KXZ54135.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Pkinase PF00069.25 KXZ54137.1 - 3.5e-41 141.3 0.0 4.7e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54137.1 - 2.4e-19 69.6 0.0 3.5e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ54137.1 - 1.7e-06 27.6 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ54137.1 - 0.013 15.5 0.1 0.093 12.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ54137.1 - 0.028 13.2 0.0 0.057 12.2 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase CAP PF00188.26 KXZ54141.1 - 0.053 14.4 0.0 0.077 13.8 0.0 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 KXZ54144.1 - 6.8e-07 30.2 0.1 0.0068 17.2 0.1 3.0 1 1 2 3 3 3 2 Cysteine-rich secretory protein family CAP PF00188.26 KXZ54145.1 - 3.4e-08 34.4 1.3 1.1 10.2 0.0 4.5 4 0 0 4 4 4 3 Cysteine-rich secretory protein family Ricin_B_lectin PF00652.22 KXZ54145.1 - 0.00013 22.2 0.4 0.00078 19.7 0.2 2.4 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXZ54145.1 - 0.00014 22.5 0.2 0.18 12.6 0.0 3.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Trypan_PARP PF05887.11 KXZ54145.1 - 0.0015 18.5 5.0 0.0033 17.4 5.0 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF5579 PF17742.1 KXZ54145.1 - 0.042 13.4 2.5 4.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5579) DUF3580 PF12117.8 KXZ54145.1 - 0.082 13.1 1.4 11 6.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3580) Aminotran_1_2 PF00155.21 KXZ54146.1 - 2.3e-80 270.5 0.0 2.7e-80 270.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TetR_C_28 PF17937.1 KXZ54146.1 - 0.15 12.5 1.9 3.3 8.2 0.1 2.9 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KXZ54147.1 - 4.5e-47 159.9 0.1 4.9e-33 114.3 0.0 2.8 2 1 1 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KXZ54147.1 - 1.2e-38 132.6 5.2 3e-37 128.0 5.2 2.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus zf-MYND PF01753.18 KXZ54148.1 - 0.0073 16.4 6.5 0.0073 16.4 6.5 2.5 2 0 0 2 2 2 1 MYND finger STT3 PF02516.14 KXZ54149.1 - 1.4e-93 314.4 26.6 1.2e-88 298.2 24.8 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pep1_7 PF17232.2 KXZ54149.1 - 0.23 12.0 0.1 0.56 10.7 0.1 1.6 1 0 0 1 1 1 0 Elicitor peptide 1-7 LCM PF04072.14 KXZ54150.1 - 2.1e-06 27.8 0.0 6.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase FAST_1 PF06743.15 KXZ54151.1 - 0.16 11.9 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Dus PF01207.17 KXZ54152.1 - 1.8e-50 171.8 0.0 2.3e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NUDIX PF00293.28 KXZ54153.1 - 6.8e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF1631 PF07793.11 KXZ54153.1 - 3 6.2 5.2 4.4 5.6 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) CHD5 PF04420.14 KXZ54154.1 - 0.0097 15.8 1.6 0.085 12.7 1.6 2.0 1 1 0 1 1 1 1 CHD5-like protein DUF1192 PF06698.11 KXZ54154.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1980 PF09323.10 KXZ54155.1 - 8.3e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) RSN1_7TM PF02714.15 KXZ54155.1 - 0.083 12.2 5.9 0.11 11.7 5.1 1.6 1 1 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate DUF525 PF04379.14 KXZ54156.1 - 1.3e-18 67.0 0.0 2.1e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 ApaG domain DUF4139 PF13598.6 KXZ54156.1 - 0.14 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) C2 PF00168.30 KXZ54157.1 - 2.3e-18 66.4 0.0 3.2e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain Glyco_transf_90 PF05686.12 KXZ54158.1 - 1.5e-15 57.0 0.1 6e-08 32.0 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF4455 PF14643.6 KXZ54159.1 - 2.4e-111 372.7 0.1 2.4e-111 372.7 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4455) DUF4456 PF14644.6 KXZ54159.1 - 2.7e-41 141.6 0.0 2.7e-41 141.6 0.0 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4456) RHH_3 PF12651.7 KXZ54159.1 - 0.039 13.9 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain DUF2291 PF10054.9 KXZ54159.1 - 0.53 10.0 4.0 1.4 8.6 4.0 1.7 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) Tox-GHH PF15636.6 KXZ54159.1 - 0.55 10.2 3.8 0.31 11.0 0.1 2.4 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin cwf18 PF08315.12 KXZ54159.1 - 0.66 10.6 5.9 0.66 10.6 0.9 3.7 2 1 0 2 2 2 0 cwf18 pre-mRNA splicing factor RmlD_sub_bind PF04321.17 KXZ54160.1 - 6.9e-15 54.9 0.0 1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXZ54160.1 - 6e-14 52.1 0.0 8.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ54160.1 - 0.0033 16.9 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXZ54160.1 - 0.0051 16.0 0.0 0.0095 15.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DHHW PF14286.6 KXZ54160.1 - 0.015 14.6 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 DHHW protein adh_short PF00106.25 KXZ54160.1 - 0.1 12.0 0.1 1.7 8.1 0.0 2.6 2 1 1 3 3 3 0 short chain dehydrogenase Glyco_tran_WecB PF03808.13 KXZ54160.1 - 0.17 11.8 0.0 0.6 10.0 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Hist_deacetyl PF00850.19 KXZ54161.1 - 7.1e-80 268.7 0.0 8.6e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.32 KXZ54162.1 - 1.4e-15 57.4 0.2 0.0017 19.2 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ54162.1 - 9.3e-10 38.7 0.0 0.04 14.2 0.0 4.4 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KXZ54162.1 - 0.33 9.7 0.0 0.51 9.0 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like FCP1_C PF09309.10 KXZ54162.1 - 3.8 7.3 6.7 28 4.5 0.0 2.7 2 1 0 2 2 2 0 FCP1, C-terminal DUF4431 PF14485.6 KXZ54163.1 - 0.018 14.8 0.3 0.036 13.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) COG2 PF06148.11 KXZ54164.1 - 2.8e-05 24.2 0.9 4.5e-05 23.5 0.9 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KXZ54164.1 - 0.00079 19.8 9.2 0.0088 16.5 1.7 2.4 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.6 KXZ54164.1 - 0.0014 18.9 1.0 0.0016 18.7 1.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit IFT57 PF10498.9 KXZ54164.1 - 0.021 13.8 7.5 0.028 13.4 7.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KXZ54164.1 - 0.028 13.3 3.4 0.038 12.9 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SKA1 PF07160.12 KXZ54164.1 - 0.033 14.0 3.0 0.039 13.8 3.0 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF148 PF02520.17 KXZ54164.1 - 0.046 13.8 7.8 0.076 13.1 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 Exonuc_VII_L PF02601.15 KXZ54164.1 - 0.047 13.3 2.5 0.047 13.3 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MscS_porin PF12795.7 KXZ54164.1 - 0.047 13.2 15.7 0.015 14.8 12.9 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Glutaredoxin2_C PF04399.13 KXZ54164.1 - 0.049 13.5 0.2 0.079 12.8 0.2 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain EzrA PF06160.12 KXZ54164.1 - 0.061 11.5 1.0 0.072 11.3 1.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FliJ PF02050.16 KXZ54164.1 - 0.062 13.5 8.0 0.1 12.8 8.0 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein DUF1664 PF07889.12 KXZ54164.1 - 0.084 12.9 5.4 0.14 12.2 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KXZ54164.1 - 0.09 12.1 2.7 0.1 12.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 KXZ54164.1 - 0.12 11.7 2.1 0.16 11.3 2.1 1.1 1 0 0 1 1 1 0 Tropomyosin DUF3450 PF11932.8 KXZ54164.1 - 0.13 11.6 7.8 0.18 11.1 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KXZ54164.1 - 0.15 12.3 10.0 0.11 12.8 8.6 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Cast PF10174.9 KXZ54164.1 - 0.15 10.2 4.2 0.18 10.0 4.2 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone V-ATPase_C PF03223.15 KXZ54164.1 - 0.19 11.1 3.0 0.25 10.7 3.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit C COG6 PF06419.11 KXZ54164.1 - 0.22 9.7 5.7 0.31 9.2 5.7 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF4665 PF15679.5 KXZ54164.1 - 0.29 11.8 2.8 9.3 6.9 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) DUF4763 PF15960.5 KXZ54164.1 - 0.29 10.4 5.7 0.42 9.9 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1043 PF06295.12 KXZ54164.1 - 0.33 11.0 7.2 0.37 10.8 6.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) RmuC PF02646.16 KXZ54164.1 - 0.43 9.7 7.1 0.62 9.2 7.1 1.3 1 0 0 1 1 1 0 RmuC family Phage_GP20 PF06810.11 KXZ54164.1 - 0.68 9.7 5.1 1.6 8.5 5.1 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 Sec34 PF04136.15 KXZ54164.1 - 0.79 9.6 5.6 1.4 8.8 5.6 1.5 1 0 0 1 1 1 0 Sec34-like family DUF1720 PF08226.11 KXZ54164.1 - 1.1 9.7 26.9 20 5.7 26.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) HemX PF04375.14 KXZ54164.1 - 2 7.7 12.1 2.7 7.2 12.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SlyX PF04102.12 KXZ54164.1 - 2.1 9.0 12.0 11 6.8 10.9 2.5 1 1 1 2 2 2 0 SlyX FlxA PF14282.6 KXZ54164.1 - 6.2 6.9 17.5 34 4.5 17.5 2.1 1 1 0 1 1 1 0 FlxA-like protein APP_amyloid PF10515.9 KXZ54164.1 - 7.7 7.1 6.0 17 6.0 0.4 2.4 1 1 1 2 2 2 0 Beta-amyloid precursor protein C-terminus Glyco_transf_49 PF13896.6 KXZ54165.1 - 9.3e-33 114.0 0.1 8.1e-16 58.3 0.1 3.0 3 0 0 3 3 3 3 Glycosyl-transferase for dystroglycan CAP_N PF01213.19 KXZ54165.1 - 0.047 13.2 4.9 0.07 12.6 4.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KXZ54165.1 - 0.8 9.8 11.6 2.2 8.4 11.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Exostosin PF03016.15 KXZ54166.1 - 4.7e-32 111.4 0.1 1.1e-16 60.9 0.0 2.4 2 0 0 2 2 2 2 Exostosin family BTB PF00651.31 KXZ54166.1 - 1.7e-08 34.7 0.0 4.8e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain EGF_2 PF07974.13 KXZ54166.1 - 2.2e-05 24.7 52.6 7.8e-05 23.0 7.4 3.9 4 0 0 4 4 4 3 EGF-like domain EGF_Tenascin PF18720.1 KXZ54166.1 - 0.0025 17.8 9.6 0.0025 17.8 9.6 3.6 3 0 0 3 3 3 1 Tenascin EGF domain Ank_2 PF12796.7 KXZ54167.1 - 3.3e-09 37.2 0.1 0.013 16.1 0.1 4.8 2 2 5 7 7 7 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54167.1 - 5.5e-08 32.5 1.1 1.9 9.3 0.0 7.8 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.6 KXZ54167.1 - 3e-06 27.6 4.6 0.46 11.1 0.0 6.0 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ54167.1 - 4.5e-05 23.6 0.8 0.32 11.4 0.0 5.1 2 2 4 6 6 6 1 Ankyrin repeats (many copies) P2_Phage_GpR PF06891.11 KXZ54167.1 - 0.29 11.2 2.0 13 5.9 0.0 3.3 2 1 1 3 3 3 0 P2 phage tail completion protein R (GpR) Ank_2 PF12796.7 KXZ54168.1 - 6.5e-11 42.7 0.0 0.00028 21.4 0.0 5.7 5 1 0 6 6 6 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54168.1 - 2.5e-09 37.5 0.3 0.13 12.9 0.0 6.2 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54168.1 - 0.017 15.6 6.5 1.2e+02 3.8 0.1 7.6 9 2 2 11 11 11 0 Ankyrin repeat Ank_5 PF13857.6 KXZ54168.1 - 0.022 15.1 0.7 11 6.5 0.0 4.4 2 1 2 4 4 4 0 Ankyrin repeats (many copies) ATX_III PF08098.11 KXZ54168.1 - 4 7.6 8.7 12 6.0 1.3 2.9 2 0 0 2 2 2 0 Anemonia sulcata toxin III family GDI PF00996.18 KXZ54169.1 - 1e-228 759.1 0.0 1.1e-228 758.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 KXZ54169.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SH3_14 PF18343.1 KXZ54169.1 - 0.12 12.4 0.3 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 Dda helicase SH3 domain WW PF00397.26 KXZ54170.1 - 9.1e-10 38.5 0.1 6.3e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KXZ54170.1 - 0.081 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain mTERF PF02536.14 KXZ54172.1 - 1.1e-05 24.6 0.0 1.9e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 mTERF INTS5_C PF14838.6 KXZ54172.1 - 0.18 10.4 0.0 0.23 10.1 0.0 1.0 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus EF_TS PF00889.19 KXZ54174.1 - 1.7e-57 194.4 17.4 6.8e-29 101.0 4.9 4.7 2 2 0 2 2 2 2 Elongation factor TS S1 PF00575.23 KXZ54174.1 - 1.7e-16 60.3 0.2 1.1e-11 44.9 0.3 3.4 2 1 0 2 2 2 2 S1 RNA binding domain UBA PF00627.31 KXZ54174.1 - 0.0009 19.1 0.1 0.092 12.7 0.1 2.7 2 0 0 2 2 2 1 UBA/TS-N domain HOIP-UBA PF16678.5 KXZ54174.1 - 0.0044 17.0 2.2 0.17 11.9 0.5 2.8 2 0 0 2 2 2 1 HOIP UBA domain pair RNase_II_C_S1 PF18614.1 KXZ54174.1 - 0.027 14.4 2.4 0.046 13.7 0.2 2.6 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain ATPase PF06745.13 KXZ54174.1 - 0.043 13.2 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 KaiC DUF4037 PF13228.6 KXZ54174.1 - 0.057 14.2 0.2 5.3 7.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) Ponericin PF07442.11 KXZ54174.1 - 0.061 13.4 2.3 8.7 6.5 0.2 3.3 2 0 0 2 2 2 0 Ponericin Erp_C PF06780.11 KXZ54174.1 - 0.71 9.9 4.6 0.83 9.7 0.2 3.2 3 0 0 3 3 3 0 Erp protein C-terminus DUF1296 PF06972.11 KXZ54174.1 - 2.4 8.4 4.5 16 5.7 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1296) DnaJ-X PF14308.6 KXZ54175.1 - 0.057 12.8 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing eRF1_1 PF03463.15 KXZ54177.1 - 7.1e-42 142.5 0.0 1e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KXZ54177.1 - 5e-23 81.7 0.0 9.2e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KXZ54177.1 - 2.6e-22 79.6 0.0 4e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 BTB PF00651.31 KXZ54178.1 - 6.2e-07 29.6 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Amidohydro_1 PF01979.20 KXZ54180.1 - 2.9e-34 118.9 0.0 4.4e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXZ54180.1 - 3.5e-07 30.1 4.0 1.2e-06 28.4 4.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family DEC-1_N PF04625.13 KXZ54180.1 - 0.62 9.0 4.5 1.4 7.9 4.5 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Trypsin_2 PF13365.6 KXZ54181.1 - 3.1e-09 37.9 0.0 5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain CCDC-167 PF15188.6 KXZ54181.1 - 0.001 19.3 12.1 0.0019 18.5 12.1 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 NRBF2 PF08961.10 KXZ54181.1 - 0.011 15.4 2.8 0.017 14.8 2.8 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ABC_tran_CTD PF16326.5 KXZ54181.1 - 0.018 15.3 9.8 0.038 14.2 9.8 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF1764 PF08576.10 KXZ54181.1 - 0.31 11.9 3.7 0.57 11.1 3.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Yuri_gagarin PF15934.5 KXZ54181.1 - 0.48 10.2 9.1 0.74 9.6 9.1 1.2 1 0 0 1 1 1 0 Yuri gagarin YabA PF06156.13 KXZ54181.1 - 0.73 10.5 5.9 1.6 9.4 5.9 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Peptidase_S49_N PF08496.10 KXZ54181.1 - 0.88 9.6 8.6 1.9 8.6 8.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FapA PF03961.13 KXZ54181.1 - 1.7 7.2 9.5 2.3 6.7 9.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4337 PF14235.6 KXZ54181.1 - 2.1 8.4 4.3 3.3 7.8 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Tho2 PF11262.8 KXZ54181.1 - 2.4 7.3 7.4 3.8 6.6 7.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Hint PF01079.20 KXZ54182.1 - 7.6e-28 97.5 0.0 1.3e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Hint module EF-hand_1 PF00036.32 KXZ54182.1 - 0.012 15.2 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KXZ54182.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ54182.1 - 0.031 14.2 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain PT-HINT PF07591.11 KXZ54182.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain Ank_2 PF12796.7 KXZ54183.1 - 4.9e-10 39.9 2.8 0.043 14.4 0.0 4.3 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54183.1 - 0.00019 21.6 2.4 3.3 8.6 0.0 5.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KXZ54183.1 - 0.05 13.9 8.2 4.6 7.7 0.0 5.8 5 2 1 6 6 6 0 Ankyrin repeats (many copies) BLACT_WH PF17778.1 KXZ54183.1 - 1.3 9.1 4.7 2.3 8.3 0.1 3.2 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain Pkinase_Tyr PF07714.17 KXZ54184.1 - 1.8e-29 102.8 0.0 4.9e-29 101.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ54184.1 - 1.9e-24 86.5 0.0 1.6e-22 80.1 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain APH PF01636.23 KXZ54184.1 - 0.037 13.9 0.1 0.22 11.4 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ54184.1 - 0.094 12.1 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hint PF01079.20 KXZ54185.1 - 3.4e-27 95.4 0.0 5.8e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Hint module EF-hand_1 PF00036.32 KXZ54185.1 - 0.012 15.1 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KXZ54185.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ54185.1 - 0.033 14.1 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain DUF3464 PF11947.8 KXZ54185.1 - 0.042 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PMI_typeI PF01238.21 KXZ54187.1 - 4.9e-90 302.4 0.0 7.5e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Sec23_helical PF04815.15 KXZ54187.1 - 1.3e-09 37.8 0.0 4.2e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_trunk PF04811.15 KXZ54187.1 - 1.7e-07 31.1 0.0 0.0011 18.5 0.0 3.0 3 0 0 3 3 3 2 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 KXZ54187.1 - 1.7e-07 31.1 8.7 2.9e-07 30.4 8.7 1.3 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KXZ54187.1 - 0.097 13.4 0.0 0.43 11.4 0.0 1.9 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain CAP_N PF01213.19 KXZ54187.1 - 0.32 10.4 7.8 0.48 9.9 2.8 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.22 KXZ54188.1 - 8e-31 107.3 0.0 3.9e-17 62.1 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 PK_C PF02887.16 KXZ54189.1 - 2.3e-21 76.2 0.1 6.2e-21 74.8 0.1 1.7 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain PK PF00224.21 KXZ54189.1 - 2.3e-19 69.5 0.0 3.7e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain RibD_C PF01872.17 KXZ54189.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 RibD C-terminal domain PK PF00224.21 KXZ54190.1 - 1.1e-35 123.2 0.0 1.3e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain AAA_2 PF07724.14 KXZ54191.1 - 4.9e-18 65.8 0.0 8.9e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) PHD PF00628.29 KXZ54191.1 - 1.1e-10 41.2 3.7 1.1e-10 41.2 3.7 3.7 5 1 0 5 5 4 1 PHD-finger AAA PF00004.29 KXZ54191.1 - 2.8e-10 40.7 0.3 2.5e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ54191.1 - 1.7e-06 28.1 0.2 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ54191.1 - 0.00011 22.5 0.1 0.00051 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 KXZ54191.1 - 0.00056 19.1 0.0 0.0078 15.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain GATA PF00320.27 KXZ54191.1 - 0.003 17.1 8.5 0.003 17.1 8.5 4.8 4 0 0 4 4 4 1 GATA zinc finger Zeta_toxin PF06414.12 KXZ54191.1 - 0.0041 16.4 0.0 0.009 15.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 KXZ54191.1 - 0.0047 16.3 0.1 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ54191.1 - 0.0059 17.0 2.5 0.032 14.6 2.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KXZ54191.1 - 0.016 15.4 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXZ54191.1 - 0.021 14.5 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Myc_N PF01056.18 KXZ54191.1 - 0.029 14.3 0.3 0.14 12.0 0.3 2.2 1 0 0 1 1 1 0 Myc amino-terminal region AAA_18 PF13238.6 KXZ54191.1 - 0.046 14.3 0.0 0.093 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXZ54191.1 - 0.052 12.7 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KXZ54191.1 - 0.074 13.3 0.8 0.13 12.5 0.1 1.9 2 0 0 2 2 1 0 AAA domain ArfGap PF01412.18 KXZ54191.1 - 0.81 9.8 17.1 10 6.2 0.2 4.9 5 0 0 5 5 5 0 Putative GTPase activating protein for Arf SDA1 PF05285.12 KXZ54191.1 - 1.3 8.3 11.1 0.11 11.9 2.8 2.5 2 0 0 2 2 2 0 SDA1 TPR_12 PF13424.6 KXZ54192.1 - 1.4e-22 79.7 21.0 2.6e-11 43.6 2.8 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ54192.1 - 4.6e-13 48.6 23.1 2.4e-06 27.2 1.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ54192.1 - 0.00029 20.7 12.1 0.27 11.4 1.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ54192.1 - 0.00054 19.8 11.5 0.2 11.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ54192.1 - 0.0012 18.5 5.5 0.65 9.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ54192.1 - 0.0043 17.7 2.2 0.0043 17.7 2.2 7.7 6 3 2 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ54192.1 - 0.0045 17.5 17.9 0.061 13.8 8.8 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ54192.1 - 0.0064 17.0 10.5 2.9 8.7 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXZ54192.1 - 0.035 13.6 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR TPR_20 PF14561.6 KXZ54192.1 - 0.04 14.3 13.9 0.34 11.3 0.5 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Response_reg PF00072.24 KXZ54193.1 - 3.2e-29 101.4 0.5 8.1e-28 96.8 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KXZ54193.1 - 1.1e-28 100.0 2.4 2.1e-28 99.1 1.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXZ54193.1 - 1.7e-14 53.6 9.6 3.9e-13 49.2 0.0 3.7 4 0 0 4 4 3 2 His Kinase A (phospho-acceptor) domain Guanylate_cyc PF00211.20 KXZ54193.1 - 1.1e-11 44.7 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Bac_rhodopsin PF01036.18 KXZ54193.1 - 1.6e-10 41.0 16.3 2.7e-10 40.2 16.3 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein FPP PF05911.11 KXZ54193.1 - 0.0035 15.6 4.1 0.0056 15.0 4.1 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil HATPase_c_3 PF13589.6 KXZ54193.1 - 0.0045 16.8 0.1 0.0089 15.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CENP-F_leu_zip PF10473.9 KXZ54193.1 - 0.0045 17.0 6.1 0.011 15.8 6.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Leu_zip PF15294.6 KXZ54193.1 - 0.0087 15.6 2.5 0.016 14.8 2.5 1.3 1 0 0 1 1 1 1 Leucine zipper SAM_1 PF00536.30 KXZ54193.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXZ54193.1 - 0.011 15.9 0.1 0.06 13.5 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF4795 PF16043.5 KXZ54193.1 - 0.021 14.4 0.4 0.049 13.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) GAS PF13851.6 KXZ54193.1 - 0.11 11.8 4.4 0.26 10.6 4.4 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 KXZ54193.1 - 0.14 10.1 0.4 0.22 9.4 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SKA2 PF16740.5 KXZ54193.1 - 0.17 11.6 5.4 0.44 10.4 1.2 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 TMF_DNA_bd PF12329.8 KXZ54193.1 - 0.24 11.4 8.0 4.8 7.2 2.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PMC2NT PF08066.12 KXZ54193.1 - 0.33 11.7 0.9 2.9 8.6 0.1 2.7 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF4407 PF14362.6 KXZ54193.1 - 0.39 10.0 14.2 0.84 8.9 14.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4763 PF15960.5 KXZ54193.1 - 0.41 9.9 2.2 0.75 9.0 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF724 PF05266.14 KXZ54193.1 - 0.44 10.4 4.8 1 9.2 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tektin PF03148.14 KXZ54193.1 - 0.46 9.2 6.7 3.6 6.2 0.3 2.2 2 0 0 2 2 2 0 Tektin family AATF-Che1 PF13339.6 KXZ54193.1 - 0.48 11.1 2.3 1.3 9.8 2.3 1.7 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor SYCE1 PF15233.6 KXZ54193.1 - 0.61 10.1 4.8 1.5 8.9 4.8 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Peptidase_M50B PF13398.6 KXZ54193.1 - 0.76 9.4 14.4 1.3 8.6 14.4 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DUF3584 PF12128.8 KXZ54193.1 - 0.96 6.9 7.7 1.5 6.2 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlxA PF14282.6 KXZ54193.1 - 1 9.4 13.0 0.55 10.3 4.8 3.2 2 1 0 2 2 2 0 FlxA-like protein Filament PF00038.21 KXZ54193.1 - 1 8.9 11.1 0.94 9.0 2.6 2.4 1 1 1 2 2 2 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 KXZ54193.1 - 1 9.5 5.6 3.4 7.9 5.6 1.9 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4140 PF13600.6 KXZ54193.1 - 1.1 9.8 9.1 5.2 7.6 0.5 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 KXZ54193.1 - 1.4 8.9 11.9 1.8 8.6 4.7 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KXZ54193.1 - 1.7 7.5 11.5 3 6.6 11.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 KXZ54193.1 - 1.8 7.1 4.0 2.7 6.5 4.0 1.1 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 KXZ54193.1 - 2 8.3 11.2 4.8 7.0 4.2 2.8 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.11 KXZ54193.1 - 2 8.6 17.8 40 4.3 18.0 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXZ54193.1 - 2.6 6.8 5.8 4.4 6.1 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) BRE1 PF08647.11 KXZ54193.1 - 3.9 7.6 7.8 12 6.1 7.4 2.0 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 KXZ54193.1 - 4.1 6.6 12.2 16 4.7 12.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 KXZ54193.1 - 5.5 7.4 8.0 45 4.5 3.7 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain Wtap PF17098.5 KXZ54193.1 - 5.7 6.9 10.9 0.69 9.8 2.3 2.5 1 1 0 2 2 2 0 WTAP/Mum2p family Tctex-1 PF03645.13 KXZ54195.1 - 1.8e-27 95.6 0.0 2.1e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family RabGAP-TBC PF00566.18 KXZ54196.1 - 1.4e-05 24.8 2.9 0.00024 20.8 0.1 3.0 3 0 0 3 3 3 2 Rab-GTPase-TBC domain DUF1796 PF08795.10 KXZ54197.1 - 0.16 11.9 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Chloroa_b-bind PF00504.21 KXZ54198.1 - 3.4e-12 47.2 0.2 7.9e-12 46.0 0.2 1.7 1 1 0 1 1 1 1 Chlorophyll A-B binding protein ANTH PF07651.16 KXZ54199.1 - 3.7e-56 190.2 0.0 4.3e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KXZ54199.1 - 1.5e-05 25.1 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain SET PF00856.28 KXZ54200.1 - 1.5e-22 80.7 0.3 1e-21 78.1 0.2 2.5 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KXZ54200.1 - 4.3e-14 52.3 5.3 1.1e-13 51.0 5.3 1.7 1 0 0 1 1 1 1 AWS domain FAST_1 PF06743.15 KXZ54201.1 - 5.5e-05 23.0 0.0 1.2 9.1 0.0 3.8 3 2 2 5 5 5 2 FAST kinase-like protein, subdomain 1 NAD_binding_10 PF13460.6 KXZ54202.1 - 0.003 17.5 3.7 0.0034 17.3 2.8 1.5 1 1 0 1 1 1 1 NAD(P)H-binding PsaL PF02605.15 KXZ54202.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI NT-C2 PF10358.9 KXZ54203.1 - 3.8e-15 55.9 0.4 7.8e-15 54.9 0.4 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C1q PF00386.21 KXZ54203.1 - 0.067 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 C1q domain Pox_A_type_inc PF04508.12 KXZ54203.1 - 0.098 12.5 16.2 3 7.9 1.0 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Vps52 PF04129.12 KXZ54203.1 - 0.11 11.3 3.0 0.18 10.5 3.0 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family Spc7 PF08317.11 KXZ54203.1 - 6.7 5.5 42.7 4.2 6.2 14.8 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Leu_zip PF15294.6 KXZ54204.1 - 7.6e-05 22.4 39.2 0.023 14.2 6.7 3.6 1 1 3 4 4 4 3 Leucine zipper BST2 PF16716.5 KXZ54204.1 - 0.00036 21.1 3.3 0.00036 21.1 3.3 5.1 1 1 6 7 7 6 1 Bone marrow stromal antigen 2 TPR_9 PF13371.6 KXZ54204.1 - 0.00048 20.2 3.5 0.00048 20.2 3.5 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Tropomyosin PF00261.20 KXZ54204.1 - 0.0065 15.9 19.4 0.0065 15.9 19.4 3.0 2 1 0 2 2 1 1 Tropomyosin Rab5-bind PF09311.11 KXZ54204.1 - 0.011 15.2 15.8 0.011 15.2 15.8 3.1 1 1 1 3 3 3 0 Rabaptin-like protein DUF3573 PF12097.8 KXZ54204.1 - 0.11 11.3 3.4 0.16 10.8 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Spc7 PF08317.11 KXZ54204.1 - 0.54 9.1 49.6 0.086 11.7 17.8 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 KXZ54204.1 - 0.96 8.7 47.2 0.69 9.2 23.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KXZ54204.1 - 1.3 9.5 58.7 0.59 10.6 8.1 6.5 3 3 3 6 6 6 0 Cell division protein ZapB RasGAP_C PF03836.15 KXZ54204.1 - 1.7 8.8 23.2 3.1 7.9 2.5 3.8 1 1 3 4 4 4 0 RasGAP C-terminus Uso1_p115_C PF04871.13 KXZ54204.1 - 1.7 9.0 56.4 0.66 10.4 13.1 4.0 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 KXZ54204.1 - 3.6 7.8 58.8 0.24 11.6 21.1 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 KXZ54204.1 - 3.9 7.6 55.2 0.054 13.6 9.4 3.9 3 2 0 3 3 3 0 Designed helical repeat protein 10 domain MscS_porin PF12795.7 KXZ54204.1 - 4 6.9 55.0 1.3 8.5 11.6 3.6 1 1 3 4 4 4 0 Mechanosensitive ion channel porin domain V_ATPase_I PF01496.19 KXZ54204.1 - 4.5 5.1 26.2 3.3 5.5 6.0 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.6 KXZ54204.1 - 5.1 6.4 33.1 12 5.2 0.4 3.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) ApoC-I PF04691.12 KXZ54204.1 - 5.3 7.0 8.0 4.1 7.4 0.1 4.1 3 1 1 4 4 4 0 Apolipoprotein C-I (ApoC-1) Cauli_AT PF03233.13 KXZ54204.1 - 8.3 6.3 13.1 0.25 11.3 1.0 3.1 1 1 2 3 3 3 0 Aphid transmission protein DUF1759 PF03564.15 KXZ54204.1 - 9.5 6.1 11.1 5.1 7.0 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Mago_nashi PF02792.14 KXZ54205.1 - 2.5e-70 235.2 0.4 4.2e-70 234.4 0.4 1.3 1 1 0 1 1 1 1 Mago nashi protein Ank_2 PF12796.7 KXZ54206.1 - 4e-12 46.5 0.0 5.2e-06 26.9 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54206.1 - 0.00054 20.5 0.3 1.5 9.5 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54206.1 - 0.0011 19.2 0.4 5.6 7.9 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KXZ54206.1 - 0.014 15.7 0.4 31 5.0 0.0 3.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) DUF1731 PF08338.11 KXZ54206.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) SWIM PF04434.17 KXZ54207.1 - 9.4e-08 31.6 0.2 2.1e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.6 KXZ54207.1 - 1.6e-07 31.6 2.3 1.6e-07 31.6 2.3 1.9 2 1 0 2 2 1 1 Ring finger domain Prok-RING_1 PF14446.6 KXZ54207.1 - 0.00019 21.3 3.0 0.00022 21.1 0.7 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KXZ54207.1 - 0.0005 20.2 2.4 0.0005 20.2 2.4 1.6 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 KXZ54207.1 - 0.0026 17.8 0.6 0.0026 17.8 0.6 1.8 2 0 0 2 2 1 1 RING-type zinc-finger C1_1 PF00130.22 KXZ54207.1 - 0.011 15.5 0.7 0.011 15.5 0.7 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KXZ54207.1 - 0.012 15.5 3.1 0.019 14.8 3.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.25 KXZ54207.1 - 0.13 12.2 2.4 0.34 10.8 2.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ54207.1 - 0.14 12.1 4.4 0.77 9.7 4.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KXZ54207.1 - 0.16 12.1 4.4 0.33 11.1 4.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-rbx1 PF12678.7 KXZ54207.1 - 1.3 9.4 5.2 5.2 7.4 5.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXZ54207.1 - 4.3 7.5 7.5 0.67 10.0 2.9 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXZ54207.1 - 8.1 6.2 8.4 4.5 7.0 4.7 2.4 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type Pkinase_Tyr PF07714.17 KXZ54209.1 - 9.1e-49 166.1 0.0 1e-46 159.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ54209.1 - 3.3e-44 151.2 0.0 5e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ54209.1 - 2.2e-05 24.5 0.0 2.2e-05 24.5 0.0 3.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ54209.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain U-box PF04564.15 KXZ54210.1 - 2.4e-09 37.2 0.0 4.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain HMA PF00403.26 KXZ54211.1 - 3.2e-17 62.7 2.7 3.7e-17 62.5 2.7 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain NapD PF03927.13 KXZ54211.1 - 0.06 13.4 0.1 0.071 13.2 0.1 1.1 1 0 0 1 1 1 0 NapD protein adh_short PF00106.25 KXZ54212.1 - 1e-29 103.4 0.0 2.2e-29 102.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ54212.1 - 4.2e-17 62.5 0.0 1e-16 61.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ54212.1 - 1.2e-06 28.6 0.2 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.10 KXZ54212.1 - 0.0019 17.6 0.0 0.086 12.2 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 KXZ54212.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3664 PF12406.8 KXZ54213.1 - 0.12 13.0 5.2 0.44 11.2 5.2 2.0 1 0 0 1 1 1 0 Surface protein Nop14 PF04147.12 KXZ54213.1 - 2.7 6.1 22.9 0.012 13.9 10.4 2.2 2 0 0 2 2 2 0 Nop14-like family Ras PF00071.22 KXZ54215.1 - 1.2e-45 155.1 0.1 1.4e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ54215.1 - 2.9e-20 72.7 0.1 6.6e-20 71.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ54215.1 - 5.7e-09 35.7 0.0 6.6e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXZ54215.1 - 0.005 16.4 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXZ54215.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TetR_C_16 PF17920.1 KXZ54215.1 - 0.095 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ANAPC4_WD40 PF12894.7 KXZ54216.1 - 1.6e-06 28.3 0.0 0.087 13.1 0.0 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ54216.1 - 4.6e-06 27.3 5.6 0.03 15.2 0.1 4.9 3 1 0 3 3 3 2 WD domain, G-beta repeat DUF2415 PF10313.9 KXZ54216.1 - 0.0016 18.3 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Lipase_3 PF01764.25 KXZ54217.1 - 5.7e-22 78.1 0.0 1.3e-16 60.8 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Thioesterase PF00975.20 KXZ54217.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 KXZ54217.1 - 0.12 12.0 0.4 0.29 10.7 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KXZ54217.1 - 0.19 11.4 0.1 0.33 10.6 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein RXLR PF16810.5 KXZ54217.1 - 0.38 11.2 0.9 0.67 10.4 0.9 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Hydrolase_4 PF12146.8 KXZ54217.1 - 0.63 9.3 3.2 0.81 8.9 0.5 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Otopetrin PF03189.13 KXZ54218.1 - 0.001 18.0 2.3 0.0013 17.7 2.3 1.1 1 0 0 1 1 1 1 Otopetrin Presenilin PF01080.17 KXZ54218.1 - 0.0054 15.5 32.9 0.0082 15.0 32.9 1.2 1 0 0 1 1 1 1 Presenilin SLC12 PF03522.15 KXZ54218.1 - 0.0059 15.7 25.0 0.008 15.3 25.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 Lin-8 PF03353.15 KXZ54218.1 - 0.059 12.9 29.6 0.091 12.3 29.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 KXZ54218.1 - 0.11 10.4 23.6 0.16 9.9 23.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apt1 PF10351.9 KXZ54218.1 - 0.11 11.3 14.3 0.16 10.8 14.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MCM_bind PF09739.9 KXZ54218.1 - 0.14 10.5 22.8 0.2 10.0 22.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FAM60A PF15396.6 KXZ54218.1 - 0.24 11.4 20.8 0.4 10.6 20.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4746 PF15928.5 KXZ54218.1 - 0.26 10.7 22.4 0.38 10.1 22.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mem_trans PF03547.18 KXZ54218.1 - 0.35 9.2 0.9 0.51 8.7 0.9 1.2 1 0 0 1 1 1 0 Membrane transport protein NPR3 PF03666.13 KXZ54218.1 - 0.42 9.4 28.1 0.6 8.8 28.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 KXZ54218.1 - 0.48 9.4 15.5 0.79 8.6 15.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF572 PF04502.13 KXZ54218.1 - 0.95 9.0 26.0 1.5 8.4 26.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pkinase_fungal PF17667.1 KXZ54218.1 - 1 8.0 11.0 1.5 7.5 11.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Tim54 PF11711.8 KXZ54218.1 - 2.5 6.8 26.5 4.3 6.0 26.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.15 KXZ54218.1 - 2.8 6.6 21.4 4 6.1 21.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 KXZ54218.1 - 4.2 7.1 34.9 6.6 6.5 34.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 KXZ54218.1 - 4.9 5.8 23.5 7.2 5.2 23.5 1.1 1 0 0 1 1 1 0 Raftlin Exonuc_VII_L PF02601.15 KXZ54218.1 - 5.7 6.4 28.8 9.1 5.8 28.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PA26 PF04636.13 KXZ54218.1 - 8.1 5.2 21.8 12 4.7 21.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RRM_1 PF00076.22 KXZ54219.1 - 1e-30 105.4 0.0 3.2e-17 62.1 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ54219.1 - 6.2e-07 29.5 0.0 0.0032 17.6 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KXZ54219.1 - 1e-05 25.3 0.0 0.017 15.0 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Methyltransf_25 PF13649.6 KXZ54220.1 - 1.5e-16 60.8 0.0 2.9e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ54220.1 - 2.2e-16 60.3 0.0 4.1e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ54220.1 - 5.1e-11 42.4 0.0 7.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXZ54220.1 - 1.1e-10 41.5 0.0 1.4e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ54220.1 - 2.3e-09 37.9 0.0 3.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ54220.1 - 4.8e-08 33.0 0.0 9.5e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ54220.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 KXZ54220.1 - 0.15 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.17 KXZ54220.1 - 0.2 10.8 0.0 11 5.1 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 KXZ54220.1 - 0.26 10.2 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Borrelia_P83 PF05262.11 KXZ54221.1 - 3.1 6.2 6.5 4.4 5.7 6.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Zip PF02535.22 KXZ54222.1 - 9.1e-20 71.1 12.8 4.4e-17 62.3 1.3 2.8 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4191 PF13829.6 KXZ54222.1 - 0.29 10.5 1.0 0.62 9.4 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Phage_holin_2_4 PF16082.5 KXZ54222.1 - 0.43 10.3 9.2 0.58 9.9 6.6 2.5 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Trp_oprn_chp PF09534.10 KXZ54222.1 - 2.7 7.7 23.8 5.2 6.8 17.7 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ADH_N PF08240.12 KXZ54224.1 - 1.3e-26 92.6 3.0 2.2e-26 91.9 2.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXZ54224.1 - 3.9e-20 72.2 0.2 7.4e-20 71.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXZ54224.1 - 6.6e-08 33.7 0.1 1.2e-07 32.8 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXZ54224.1 - 2.5e-05 23.7 0.1 4e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXZ54224.1 - 0.00011 21.6 0.0 0.00027 20.3 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXZ54224.1 - 0.03 14.2 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF563 PF04577.14 KXZ54225.1 - 1.4e-13 51.4 0.3 7.3e-13 49.1 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF563) MBF1 PF08523.10 KXZ54226.1 - 9.5e-24 83.7 5.0 9.5e-24 83.7 5.0 2.0 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KXZ54226.1 - 2.6e-14 53.0 0.3 4.8e-14 52.2 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KXZ54226.1 - 3.1e-07 30.6 0.0 7.8e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KXZ54226.1 - 5.4e-05 23.1 0.0 7.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KXZ54226.1 - 0.016 15.7 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 KXZ54226.1 - 0.05 13.5 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_6 PF12774.7 KXZ54227.1 - 7.9e-165 547.6 0.0 1e-163 544.0 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ54227.1 - 1.8e-132 442.3 9.0 1.8e-132 442.3 9.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXZ54227.1 - 1.1e-117 392.7 0.1 1.2e-116 389.2 0.0 2.7 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KXZ54227.1 - 1.5e-105 352.2 0.1 1.3e-104 349.2 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXZ54227.1 - 3.6e-89 297.7 0.5 1.5e-88 295.6 0.0 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ54227.1 - 1.6e-84 281.9 0.1 1.5e-80 269.0 0.0 3.4 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ54227.1 - 3.2e-51 173.4 0.0 1e-50 171.8 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KXZ54227.1 - 1.4e-50 172.2 6.0 2.6e-50 171.4 6.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KXZ54227.1 - 2e-48 163.4 0.0 1.3e-46 157.5 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXZ54227.1 - 6.7e-29 100.6 0.0 3e-28 98.5 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KXZ54227.1 - 2.7e-18 66.0 0.2 1.2e-17 64.0 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KXZ54227.1 - 4.5e-17 62.3 0.0 0.0001 22.3 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ54227.1 - 4e-07 30.4 3.2 0.1 12.9 0.0 6.1 6 0 0 6 6 6 1 AAA domain AAA PF00004.29 KXZ54227.1 - 3.1e-05 24.4 0.0 0.69 10.3 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXZ54227.1 - 4.6e-05 23.9 0.4 1.7 9.0 0.0 4.6 4 0 0 4 4 2 2 AAA ATPase domain DUF853 PF05872.12 KXZ54227.1 - 0.0021 16.7 0.6 2.3 6.7 0.0 3.2 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) RNA_helicase PF00910.22 KXZ54227.1 - 0.0085 16.5 0.0 1.3 9.5 0.0 3.5 3 0 0 3 3 3 1 RNA helicase T2SSE PF00437.20 KXZ54227.1 - 0.0088 15.1 0.0 0.22 10.5 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 KXZ54227.1 - 0.011 16.3 0.0 0.24 12.0 0.0 3.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KXZ54227.1 - 0.025 14.3 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.15 KXZ54227.1 - 0.096 12.7 0.1 6.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF87 PF01935.17 KXZ54227.1 - 1.8 8.6 4.8 1.5 8.8 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain Laminin_II PF06009.12 KXZ54227.1 - 5.2 7.1 19.8 0.84 9.6 8.4 3.2 3 0 0 3 3 2 0 Laminin Domain II hnRNP_Q_AcD PF18360.1 KXZ54229.1 - 0.00011 22.1 0.2 0.019 14.9 0.0 2.4 2 0 0 2 2 2 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain FliS_cochap PF16522.5 KXZ54229.1 - 0.034 14.1 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 CCDC23 PF15674.5 KXZ54229.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 Peptidase_M43 PF05572.13 KXZ54230.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Pinin_SDK_memA PF04696.13 KXZ54232.1 - 2.1e-05 24.6 16.2 0.00015 21.8 1.6 3.2 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region DUF4207 PF13904.6 KXZ54232.1 - 3.7 7.2 16.2 0.034 13.8 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Ribosomal_L21p PF00829.21 KXZ54233.1 - 1.4e-29 102.4 0.1 1.9e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Sulfotransfer_1 PF00685.27 KXZ54235.1 - 5.8e-13 48.9 0.4 7.3e-13 48.6 0.4 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXZ54235.1 - 5.2e-05 23.7 0.7 0.00056 20.4 0.7 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KXZ54235.1 - 0.014 15.3 0.7 0.019 14.9 0.7 1.4 1 1 0 1 1 1 0 Sulfotransferase family Amino_oxidase PF01593.24 KXZ54236.1 - 8.7e-12 45.1 0.0 4.3e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ54236.1 - 1.2e-11 44.7 0.1 2.7e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXZ54236.1 - 3.5e-06 26.4 0.2 5.2e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXZ54236.1 - 1.4e-05 24.1 0.2 2.1e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KXZ54236.1 - 5.8e-05 22.8 0.3 0.00011 21.9 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXZ54236.1 - 0.00013 21.4 0.3 0.00019 20.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXZ54236.1 - 0.00024 20.5 0.0 0.00037 19.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ54236.1 - 0.00026 20.5 0.3 0.00042 19.8 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ54236.1 - 0.0018 17.6 0.1 0.0032 16.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXZ54236.1 - 0.0091 15.1 0.4 0.025 13.7 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KXZ54236.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXZ54236.1 - 0.014 14.5 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF1647 PF07801.11 KXZ54237.1 - 9.1e-09 35.2 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Rubis-subs-bind PF09273.11 KXZ54238.1 - 0.00026 21.7 0.4 0.00094 19.9 0.0 2.2 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Ribosomal_L17 PF01196.19 KXZ54240.1 - 7.1e-30 103.8 0.1 9.7e-30 103.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 DUF1640 PF07798.11 KXZ54242.1 - 3.5e-31 108.6 14.3 3.8e-31 108.5 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) B2 PF11473.8 KXZ54242.1 - 0.015 15.1 0.3 0.49 10.2 0.0 2.4 1 1 0 2 2 2 0 RNA binding protein B2 SF-assemblin PF06705.11 KXZ54242.1 - 0.032 13.6 10.5 0.042 13.2 10.5 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 KXZ54242.1 - 0.098 12.7 3.0 0.21 11.6 2.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 KXZ54242.1 - 0.099 12.2 5.8 0.12 12.0 5.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0176_N PF17773.1 KXZ54242.1 - 0.11 12.8 2.2 0.13 12.7 1.0 1.7 2 0 0 2 2 2 0 UPF0176 acylphosphatase like domain Golgin_A5 PF09787.9 KXZ54242.1 - 0.26 10.7 14.0 0.33 10.4 14.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KXZ54242.1 - 0.3 11.1 8.9 0.18 11.9 5.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 KXZ54242.1 - 0.34 9.5 7.9 0.41 9.2 7.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CorA PF01544.18 KXZ54242.1 - 0.39 10.0 8.0 0.48 9.7 8.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Tox-ODYAM1 PF15642.6 KXZ54242.1 - 0.45 9.4 7.5 0.52 9.2 7.5 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus NPV_P10 PF05531.12 KXZ54242.1 - 0.55 10.7 7.8 2.5 8.6 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1451 PF07295.11 KXZ54242.1 - 1.6 8.8 8.4 2.3 8.2 8.1 1.4 1 1 0 1 1 1 0 Zinc-ribbon containing domain TcpS PF17456.2 KXZ54242.1 - 1.6 8.8 7.4 1 9.4 2.0 2.0 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S ACCA PF03255.14 KXZ54242.1 - 2.2 8.1 10.6 5.6 6.8 8.0 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit RNase_J_C PF17770.1 KXZ54242.1 - 3.5 8.7 6.7 5 8.2 0.4 2.5 1 1 2 3 3 3 0 Ribonuclease J C-terminal domain Nup54 PF13874.6 KXZ54242.1 - 3.9 7.6 10.3 6.8 6.8 10.3 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 YtxH PF12732.7 KXZ54242.1 - 4.5 7.9 7.7 2.5e+02 2.3 7.7 2.3 1 1 0 1 1 1 0 YtxH-like protein CHD5 PF04420.14 KXZ54242.1 - 7.6 6.4 7.4 2 8.3 0.1 2.4 2 1 0 2 2 2 0 CHD5-like protein HSP20 PF00011.21 KXZ54243.1 - 5.2e-29 100.4 0.0 6.4e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXZ54243.1 - 9.2e-07 28.3 0.0 1.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Vmethyltransf_C PF08456.10 KXZ54243.1 - 0.07 12.7 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase C-terminal BON PF04972.17 KXZ54243.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.5 2 0 0 2 2 2 0 BON domain Pex2_Pex12 PF04757.14 KXZ54244.1 - 1.7e-30 106.3 0.0 3.2e-30 105.4 0.0 1.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KXZ54244.1 - 4.4e-08 33.3 16.5 6.5e-08 32.8 15.9 1.6 1 1 1 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 KXZ54244.1 - 1.5e-07 31.2 9.0 2.2e-07 30.6 9.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ54244.1 - 7.2e-07 29.0 13.4 1.1e-06 28.4 13.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ54244.1 - 1.3e-05 24.9 17.4 4.6e-05 23.2 16.8 2.0 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ54244.1 - 2.2e-05 24.4 10.4 2.2e-05 24.4 10.4 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXZ54244.1 - 3.2e-05 24.0 14.6 5.3e-05 23.3 14.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXZ54244.1 - 0.00026 20.8 12.3 0.00058 19.7 12.3 1.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXZ54244.1 - 0.0016 18.4 10.7 0.0039 17.1 10.6 1.6 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXZ54244.1 - 0.0024 18.1 16.3 0.021 15.1 15.5 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KXZ54244.1 - 3.9 7.7 8.1 6.7 6.9 8.1 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Aminotran_5 PF00266.19 KXZ54245.1 - 2.2e-14 53.2 0.0 6.6e-14 51.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXZ54245.1 - 0.0005 19.5 0.3 0.03 13.7 0.1 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L16 PF00252.18 KXZ54247.1 - 1.1e-40 138.7 0.1 1.4e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Oxidored_FMN PF00724.20 KXZ54249.1 - 4e-69 233.5 0.0 5.1e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 KXZ54250.1 - 9e-55 185.9 0.0 1.3e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54250.1 - 1.6e-19 70.2 0.0 2.6e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Uso1_p115_C PF04871.13 KXZ54250.1 - 0.00013 22.4 0.5 0.00048 20.5 0.5 1.9 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Abhydrolase_3 PF07859.13 KXZ54252.1 - 9.9e-13 48.4 1.2 2.9e-12 46.9 0.6 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KXZ54252.1 - 1e-12 47.7 0.1 3.2e-12 46.1 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXZ54252.1 - 1.1e-08 34.9 0.0 1.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXZ54252.1 - 6.8e-08 32.5 0.1 0.00019 21.2 0.3 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ54252.1 - 2.4e-07 30.3 0.3 0.0044 16.3 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ54252.1 - 0.0001 23.0 15.6 0.00028 21.5 13.5 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KXZ54252.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 KXZ54252.1 - 0.1 12.3 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Pex19 PF04614.12 KXZ54253.1 - 4.2e-31 108.6 0.0 9.3e-31 107.5 0.0 1.8 1 1 0 1 1 1 1 Pex19 protein family MSA-2c PF12238.8 KXZ54253.1 - 0.00056 20.0 0.0 0.00098 19.2 0.0 1.3 1 0 0 1 1 1 1 Merozoite surface antigen 2c Ribosomal_S17 PF00366.20 KXZ54254.1 - 5.1e-25 87.4 0.9 6.6e-25 87.0 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Peptidase_C1 PF00112.23 KXZ54255.1 - 6.2e-44 150.7 4.2 8.4e-44 150.2 4.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KXZ54255.1 - 0.033 13.0 0.4 0.17 10.6 1.1 1.8 3 0 0 3 3 3 0 Peptidase C1-like family WD40 PF00400.32 KXZ54256.1 - 0.00054 20.7 0.5 0.38 11.7 0.1 3.5 2 0 0 2 2 2 2 WD domain, G-beta repeat PfkB PF00294.24 KXZ54257.1 - 2.8e-26 92.5 0.2 8.5e-19 68.0 0.3 2.5 2 1 0 2 2 2 2 pfkB family carbohydrate kinase AMPK1_CBM PF16561.5 KXZ54258.1 - 3.4e-15 56.0 0.0 5.6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Cep57_CLD PF14073.6 KXZ54258.1 - 0.04 14.0 1.5 0.056 13.5 1.5 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 CENP-F_leu_zip PF10473.9 KXZ54258.1 - 0.04 13.9 1.3 0.068 13.2 1.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nnf1 PF03980.14 KXZ54258.1 - 0.042 14.2 3.1 0.18 12.2 0.6 2.2 2 0 0 2 2 2 0 Nnf1 DUF3584 PF12128.8 KXZ54258.1 - 0.47 7.9 3.8 0.66 7.4 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Trimer_CC PF08954.11 KXZ54258.1 - 0.51 9.9 3.8 11 5.7 0.2 3.2 2 1 1 3 3 3 0 Trimerisation motif HSF_DNA-bind PF00447.17 KXZ54259.1 - 7.2e-28 97.0 0.0 1.2e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding APG6_N PF17675.1 KXZ54259.1 - 0.0037 17.8 0.1 0.006 17.1 0.1 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Filament PF00038.21 KXZ54259.1 - 0.0071 16.0 0.3 0.01 15.4 0.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein TMF_TATA_bd PF12325.8 KXZ54259.1 - 0.031 14.5 0.7 0.052 13.8 0.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Herpes_UL25 PF01499.16 KXZ54259.1 - 0.19 10.2 0.2 0.28 9.7 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Porphobil_deam PF01379.20 KXZ54260.1 - 2.2e-58 197.1 0.0 3.1e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain RuBisCO_small PF00101.20 KXZ54261.1 - 7.2e-42 141.3 0.0 9.6e-42 140.9 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain Ank_2 PF12796.7 KXZ54262.1 - 8.1e-18 64.8 10.2 5.3e-09 36.5 0.6 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54262.1 - 1.7e-06 28.5 1.7 0.15 12.6 0.3 3.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ54262.1 - 0.00068 19.9 9.1 0.79 10.1 0.1 4.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54262.1 - 0.001 19.3 3.7 3.1 8.7 0.0 5.0 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.30 KXZ54262.1 - 0.11 13.0 9.3 1.2 9.7 0.1 4.0 4 1 0 4 4 4 0 Ankyrin repeat Pex14_N PF04695.13 KXZ54263.1 - 0.014 16.1 0.2 0.018 15.7 0.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RuBisCO_small PF00101.20 KXZ54264.1 - 7.2e-42 141.3 0.0 9.6e-42 140.9 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain DnaJ PF00226.31 KXZ54266.1 - 1.2e-14 54.2 0.8 3.1e-10 40.0 0.1 2.6 2 0 0 2 2 2 2 DnaJ domain TPR_1 PF00515.28 KXZ54266.1 - 7.2e-13 47.8 2.7 0.00043 20.0 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ54266.1 - 2.7e-11 42.7 12.7 0.019 15.1 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ54266.1 - 1.8e-07 31.5 17.2 0.00053 20.5 0.8 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ54266.1 - 0.00015 22.0 27.2 0.91 9.9 0.3 7.3 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ54266.1 - 0.0069 16.0 3.8 3.3 7.5 0.0 3.9 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 KXZ54266.1 - 0.01 15.8 8.6 13 6.1 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat COX5A PF02284.16 KXZ54266.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va ANAPC3 PF12895.7 KXZ54266.1 - 0.17 12.1 7.6 1.5 9.1 0.1 4.2 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MerR-DNA-bind PF09278.11 KXZ54266.1 - 0.28 11.8 1.8 0.59 10.7 0.6 2.3 2 0 0 2 2 2 0 MerR, DNA binding TPR_8 PF13181.6 KXZ54266.1 - 0.44 10.9 4.2 1.2e+02 3.3 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Transp_cyt_pur PF02133.15 KXZ54267.1 - 2e-113 379.5 36.7 2.3e-113 379.3 36.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Mpv17_PMP22 PF04117.12 KXZ54268.1 - 5.7e-12 45.7 0.1 1.2e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 KXZ54269.1 - 2e-15 56.7 0.0 4.3e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DnaJ PF00226.31 KXZ54270.1 - 4.7e-17 61.9 0.2 1.2e-16 60.6 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain fn3 PF00041.21 KXZ54270.1 - 9.1e-05 22.7 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain RPT PF13446.6 KXZ54270.1 - 0.036 14.0 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Pur_ac_phosph_N PF16656.5 KXZ54270.1 - 0.14 12.7 0.2 0.84 10.3 0.1 2.5 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Macoilin PF09726.9 KXZ54270.1 - 2.8 6.4 32.7 0.013 14.1 23.2 1.7 2 0 0 2 2 2 0 Macoilin family V_ATPase_I PF01496.19 KXZ54272.1 - 4.3 5.1 13.4 6 4.6 13.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RPE65 PF03055.15 KXZ54273.1 - 1.7e-91 307.8 0.0 2e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein G-patch PF01585.23 KXZ54274.1 - 2.1e-15 56.3 1.9 8.6e-15 54.4 1.9 2.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXZ54274.1 - 6.2e-07 29.4 0.4 6.2e-07 29.4 0.4 2.8 2 0 0 2 2 2 1 G-patch domain Ank_2 PF12796.7 KXZ54280.1 - 1.5e-15 57.6 0.0 1.6e-07 31.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54280.1 - 1.6e-08 34.1 0.2 0.00046 20.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXZ54280.1 - 5.5e-07 29.7 0.5 0.0001 22.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXZ54280.1 - 1.9e-05 24.8 0.3 0.00054 20.2 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ54280.1 - 5.5e-05 23.6 0.1 0.00022 21.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ54281.1 - 1e-208 676.6 72.4 3.7e-18 65.9 0.3 16.5 1 1 17 18 18 18 18 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ54281.1 - 3.4e-178 571.1 101.5 9e-07 29.1 0.2 30.5 29 1 1 30 30 30 30 Ankyrin repeat Ank_4 PF13637.6 KXZ54281.1 - 3.8e-159 515.2 35.0 1.6e-12 47.7 0.1 20.2 8 3 17 25 25 25 24 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54281.1 - 3.2e-151 472.6 54.9 1.4e-05 25.1 0.0 31.7 31 1 1 32 32 32 30 Ankyrin repeat Ank_5 PF13857.6 KXZ54281.1 - 7.8e-149 481.8 79.8 5.6e-11 42.5 0.1 25.3 4 3 19 25 25 25 25 Ankyrin repeats (many copies) DUF1018 PF06252.12 KXZ54281.1 - 0.034 15.1 0.3 1.7e+02 3.2 0.0 5.8 7 0 0 7 7 7 0 Protein of unknown function (DUF1018) MukE PF04288.13 KXZ54281.1 - 0.26 10.2 0.2 17 4.3 0.0 3.4 3 0 0 3 3 3 0 MukE-like family HNH_repeat PF18780.1 KXZ54281.1 - 0.57 10.0 3.0 19 5.2 0.2 3.3 2 0 0 2 2 2 0 Homing endonuclease repeat CHAP PF05257.16 KXZ54281.1 - 5.9 7.5 7.7 58 4.4 0.0 4.6 4 0 0 4 4 4 0 CHAP domain TMP_2 PF06791.13 KXZ54282.1 - 0.69 9.5 5.6 3.5 7.2 1.4 2.5 2 0 0 2 2 2 0 Prophage tail length tape measure protein Pkinase PF00069.25 KXZ54284.1 - 2.6e-32 112.3 0.0 4.3e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54284.1 - 3.4e-32 111.7 0.0 9.9e-23 80.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXZ54284.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ54284.1 - 0.0023 17.9 0.4 0.0051 16.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ54284.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KXZ54284.1 - 0.028 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_C41 PF05417.11 KXZ54284.1 - 0.046 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Hepatitis E cysteine protease Pkinase PF00069.25 KXZ54286.1 - 1.7e-34 119.4 0.0 3.2e-34 118.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54286.1 - 3.6e-33 114.9 0.0 1.6e-22 80.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ54286.1 - 9.8e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ54286.1 - 0.0011 17.8 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ54286.1 - 0.0024 17.2 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 KXZ54287.1 - 2.6e-10 39.5 14.5 0.0068 16.4 0.1 6.8 6 1 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KXZ54287.1 - 7.7e-06 25.8 0.0 8.9 7.3 0.1 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 KXZ54287.1 - 0.002 18.5 4.7 0.038 14.4 0.4 3.7 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ54287.1 - 0.0028 17.4 4.4 0.79 9.5 2.4 4.7 2 1 1 3 3 3 1 Leucine rich repeat TTKRSYEDQ PF10212.9 KXZ54287.1 - 0.32 9.9 19.1 0.046 12.7 3.7 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Patatin PF01734.22 KXZ54288.1 - 3.8e-15 56.6 3.5 5.7e-09 36.5 0.4 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase PNK3P PF08645.11 KXZ54289.1 - 7.6e-51 172.0 0.0 1.1e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HHH_8 PF14716.6 KXZ54289.1 - 0.00011 22.5 2.3 0.0002 21.7 0.5 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain PBP1_TM PF14812.6 KXZ54289.1 - 8.2 6.9 9.2 1.1 9.7 4.8 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 KXZ54291.1 - 4.3e-40 137.7 0.0 8.9e-40 136.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54291.1 - 2.3e-38 132.0 0.0 3e-37 128.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ54291.1 - 0.00062 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ54291.1 - 0.00093 19.2 2.4 0.0019 18.1 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ54291.1 - 0.00099 18.0 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EcKinase PF02958.20 KXZ54291.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase TMPIT PF07851.13 KXZ54292.1 - 7.5e-48 163.4 0.1 1.5e-44 152.6 0.0 2.4 2 1 0 2 2 2 2 TMPIT-like protein Laminin_I PF06008.14 KXZ54292.1 - 0.016 14.9 0.9 0.022 14.5 0.9 1.1 1 0 0 1 1 1 0 Laminin Domain I SelK_SelG PF10961.8 KXZ54292.1 - 2.4 8.8 5.8 31 5.3 4.9 3.0 3 1 0 3 3 3 0 Selenoprotein SelK_SelG Pkinase_Tyr PF07714.17 KXZ54294.1 - 4.2e-39 134.4 0.0 1.4e-32 113.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ54294.1 - 9.1e-33 113.7 0.0 1.4e-25 90.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ54294.1 - 0.00084 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ54296.1 - 4.8e-41 140.8 0.0 1.6e-33 116.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ54296.1 - 3.5e-37 128.2 0.0 5e-27 94.9 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Kdo PF06293.14 KXZ54296.1 - 0.0031 16.9 0.1 0.0051 16.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ54296.1 - 0.012 15.6 0.1 0.045 13.7 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXZ54296.1 - 0.039 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like IHABP4_N PF16174.5 KXZ54297.1 - 0.78 10.3 5.5 0.27 11.8 0.8 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal GRP PF07172.11 KXZ54297.1 - 3 8.6 22.7 0.48 11.1 3.2 3.3 3 0 0 3 3 3 0 Glycine rich protein family DUF563 PF04577.14 KXZ54298.1 - 3.2e-11 43.8 0.0 8.3e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Terpene_synth PF01397.21 KXZ54300.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain DUF2682 PF10909.8 KXZ54300.1 - 0.072 13.6 0.1 0.15 12.5 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2682) Med15_fungi PF05397.12 KXZ54300.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 15 RPE65 PF03055.15 KXZ54301.1 - 2e-89 300.9 0.0 2.5e-89 300.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Yae1_N PF09811.9 KXZ54303.1 - 1.2e-08 34.5 1.8 1.2e-08 34.5 1.8 2.1 2 0 0 2 2 2 1 Essential protein Yae1, N terminal LIDHydrolase PF10230.9 KXZ54305.1 - 1.5e-35 123.1 0.0 3e-35 122.1 0.0 1.5 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KXZ54305.1 - 4.3e-06 27.5 14.0 4.3e-06 27.5 14.0 2.5 1 1 2 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KXZ54305.1 - 0.0038 17.4 0.3 0.0038 17.4 0.3 1.8 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 KXZ54305.1 - 0.011 15.1 0.1 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ54305.1 - 0.02 14.5 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KXZ54305.1 - 0.06 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_S18 PF01084.20 KXZ54306.1 - 9e-11 41.8 0.3 1.8e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S18 HEV_ORF1 PF02444.16 KXZ54306.1 - 0.051 14.2 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) Alginate_lyase PF05426.12 KXZ54306.1 - 0.094 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Alginate lyase Guanylate_cyc PF00211.20 KXZ54307.1 - 1.2e-62 210.8 0.0 4.6e-62 208.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PSI PF01437.25 KXZ54308.1 - 7 7.3 9.3 0.54 10.8 3.7 2.2 2 1 0 2 2 2 0 Plexin repeat Ras PF00071.22 KXZ54309.1 - 7.7e-46 155.6 0.0 9.6e-46 155.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ54309.1 - 2.3e-28 98.8 0.0 3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ54309.1 - 4.7e-12 45.7 0.0 6.4e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXZ54309.1 - 6.9e-07 29.4 0.0 1e-05 25.6 0.0 2.0 1 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXZ54309.1 - 4.8e-05 22.8 0.0 5.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXZ54309.1 - 0.00044 19.7 0.0 0.00057 19.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXZ54309.1 - 0.0009 18.8 0.1 0.067 12.7 0.0 2.6 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KXZ54309.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KXZ54309.1 - 0.017 15.1 0.0 0.047 13.6 0.0 1.8 2 1 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KXZ54309.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KXZ54309.1 - 0.023 15.1 0.0 0.064 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KXZ54309.1 - 0.043 14.0 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXZ54309.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 KXZ54309.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KXZ54309.1 - 0.12 12.6 0.0 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RETICULATA-like PF11891.8 KXZ54311.1 - 7.8e-55 185.4 0.2 1.4e-54 184.6 0.2 1.4 1 0 0 1 1 1 1 Protein RETICULATA-related zf-C3HC4 PF00097.25 KXZ54312.1 - 9.1e-05 22.2 0.3 0.0002 21.2 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ54312.1 - 9.4e-05 22.4 2.5 0.00023 21.1 2.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ54312.1 - 0.00016 21.4 2.5 0.00044 20.0 2.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ54312.1 - 0.00071 19.8 2.9 0.0015 18.8 2.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXZ54312.1 - 0.001 19.0 3.5 0.0024 17.8 3.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXZ54312.1 - 0.0056 16.5 4.9 0.013 15.4 4.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXZ54312.1 - 0.011 15.6 3.3 0.023 14.5 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXZ54312.1 - 0.018 14.9 1.4 0.041 13.8 1.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KXZ54312.1 - 0.084 13.1 3.4 0.17 12.0 3.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PsbP PF01789.16 KXZ54314.1 - 1.2e-20 74.2 0.0 1.3e-17 64.4 0.0 2.7 2 1 0 2 2 2 2 PsbP Beta_helix PF13229.6 KXZ54315.1 - 1.4e-08 34.7 0.0 7.8e-07 29.1 0.0 2.5 2 1 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 KXZ54315.1 - 0.082 12.2 0.0 0.34 10.2 0.0 1.8 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) TPR_14 PF13428.6 KXZ54317.1 - 3.5e-25 86.5 113.0 0.00064 20.3 0.9 16.8 4 4 13 17 17 17 13 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ54317.1 - 2.5e-22 79.2 116.1 2.7e-06 27.9 0.1 9.7 7 1 2 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ54317.1 - 7.7e-21 74.4 52.3 8.9e-06 26.1 1.4 10.2 7 3 4 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ54317.1 - 4.9e-18 63.7 56.0 0.019 15.1 0.1 15.2 15 0 0 15 15 15 6 Tetratricopeptide repeat Suf PF05843.14 KXZ54317.1 - 5.6e-12 46.3 0.0 0.00018 21.6 0.0 5.1 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KXZ54317.1 - 6.3e-12 45.0 21.1 0.061 13.7 0.0 11.2 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ54317.1 - 8.4e-08 31.8 6.5 16 6.0 0.0 9.8 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ54317.1 - 2.6e-06 27.6 72.4 0.022 15.0 4.5 10.9 9 4 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ54317.1 - 3.1e-05 23.6 11.7 0.12 12.2 0.0 6.9 9 0 0 9 9 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXZ54317.1 - 8.4e-05 22.5 13.6 0.58 10.2 0.7 6.8 6 1 0 6 6 6 1 Mad3/BUB1 homology region 1 TPR_7 PF13176.6 KXZ54317.1 - 0.00028 20.7 29.8 1.4 9.1 0.0 9.4 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ54317.1 - 0.0017 18.0 0.0 15 5.4 0.0 5.6 5 1 2 7 7 7 0 TPR repeat TPR_15 PF13429.6 KXZ54317.1 - 0.0029 16.9 51.3 0.43 9.7 21.4 7.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ54317.1 - 0.0034 17.9 50.8 3.2 8.6 0.1 13.8 14 1 0 14 14 14 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ54317.1 - 0.0066 16.6 0.4 0.0066 16.6 0.4 9.2 4 3 6 10 10 10 3 Tetratricopeptide repeat ChAPs PF09295.10 KXZ54317.1 - 0.23 10.4 0.5 5 6.0 0.0 2.8 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 KXZ54317.1 - 0.46 10.9 1.9 41 4.7 0.1 4.8 6 0 0 6 6 4 0 PPR repeat zf-CCHC_3 PF13917.6 KXZ54318.1 - 0.0069 16.3 0.1 0.055 13.4 0.1 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXZ54318.1 - 0.15 11.8 0.9 0.29 10.9 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KXZ54318.1 - 0.16 12.1 1.5 0.33 11.1 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Semialdhyde_dhC PF02774.18 KXZ54319.1 - 2.2e-44 151.8 0.0 3.2e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KXZ54319.1 - 7.7e-32 110.3 0.1 1.5e-31 109.3 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KXZ54319.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF572 PF04502.13 KXZ54320.1 - 0.13 11.9 11.8 0.15 11.6 11.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) VIT1 PF01988.19 KXZ54320.1 - 2.4 8.0 4.1 2.6 7.8 4.1 1.2 1 0 0 1 1 1 0 VIT family HSP70 PF00012.20 KXZ54320.1 - 4.5 5.3 9.1 5.4 5.1 9.1 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2151 PF10221.9 KXZ54320.1 - 4.6 5.7 9.2 5.3 5.5 9.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator NARP1 PF12569.8 KXZ54320.1 - 5.7 5.7 15.1 6.7 5.5 15.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RAP PF08373.10 KXZ54321.1 - 1.6e-06 28.1 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain Pkinase PF00069.25 KXZ54322.1 - 3.7e-33 115.0 0.0 2.7e-32 112.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54322.1 - 1.2e-29 103.4 0.0 2.5e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SKG6 PF08693.10 KXZ54322.1 - 8.5e-05 21.9 9.8 8.5e-05 21.9 9.8 2.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain APH PF01636.23 KXZ54322.1 - 0.00014 21.8 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ54322.1 - 0.001 18.0 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ54322.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4448 PF14610.6 KXZ54322.1 - 0.0023 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) FeoB_associated PF12669.7 KXZ54322.1 - 0.071 13.5 0.3 0.24 11.8 0.3 1.9 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Herpes_gE PF02480.16 KXZ54322.1 - 0.13 10.9 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Prominin PF05478.11 KXZ54322.1 - 0.2 9.6 0.0 0.27 9.2 0.0 1.1 1 0 0 1 1 1 0 Prominin CLAMP PF14769.6 KXZ54323.1 - 9e-19 67.8 0.0 1.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 zinc_ribbon_12 PF11331.8 KXZ54323.1 - 0.016 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon domain DUF4554 PF15091.6 KXZ54323.1 - 1.6 7.6 3.9 2.2 7.1 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Casc1_N PF15927.5 KXZ54323.1 - 5.4 6.7 26.7 8.4 6.0 26.7 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus UPF0225 PF17775.1 KXZ54324.1 - 4.8e-13 49.8 0.0 7.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 KXZ54324.1 - 0.045 13.7 1.4 0.072 13.0 1.4 1.4 1 0 0 1 1 1 0 SEC-C motif tRNA-synt_2d PF01409.20 KXZ54325.1 - 1.2e-90 303.3 0.0 1.6e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KXZ54325.1 - 1.2e-19 70.4 0.1 3.5e-19 68.8 0.1 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 KXZ54325.1 - 5.8e-11 42.0 0.1 1.4e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 KXZ54325.1 - 2e-07 30.7 0.0 1.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KXZ54325.1 - 9.3e-06 24.9 0.2 0.00032 19.9 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KXZ54325.1 - 0.0041 17.1 0.0 0.0084 16.1 0.0 1.5 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) RRM_1 PF00076.22 KXZ54327.1 - 2.3e-26 91.4 0.0 9.6e-11 41.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ54327.1 - 2.7e-05 23.9 0.0 0.12 12.2 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KXZ54327.1 - 0.042 14.0 0.0 5.7 7.1 0.0 3.3 3 1 0 3 3 3 0 RNA recognition motif FAD_syn PF06574.12 KXZ54328.1 - 6.4e-08 32.6 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase DUF1824 PF08854.10 KXZ54329.1 - 5.1e-14 52.3 0.0 1e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1824) EpuA PF11772.8 KXZ54330.1 - 0.16 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta GREB1 PF15782.5 KXZ54330.1 - 3 4.9 8.2 4 4.4 8.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Bac_surface_Ag PF01103.23 KXZ54331.1 - 3.2e-34 118.9 0.0 8.1e-34 117.6 0.0 1.6 1 1 0 1 1 1 1 Surface antigen POTRA PF07244.15 KXZ54331.1 - 1.1e-14 54.7 0.0 0.00015 22.2 0.0 3.3 3 0 0 3 3 3 3 Surface antigen variable number repeat POTRA_2 PF08479.11 KXZ54331.1 - 0.00085 19.1 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 POTRA domain, ShlB-type ShlB PF03865.13 KXZ54331.1 - 0.032 13.7 0.1 0.087 12.3 0.0 1.8 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB O-FucT PF10250.9 KXZ54332.1 - 1e-10 41.9 0.0 0.0012 18.6 0.0 3.2 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase Metallophos_2 PF12850.7 KXZ54333.1 - 1.2e-05 25.5 0.0 2.4e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KXZ54333.1 - 2.3e-05 25.0 2.9 5.9e-05 23.7 2.9 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KXZ54333.1 - 0.026 13.9 0.0 0.86 8.9 0.0 2.1 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily OAS1_C PF10421.9 KXZ54334.1 - 0.011 15.3 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus CotE PF10628.9 KXZ54334.1 - 0.041 13.5 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Outer spore coat protein E (CotE) PALP PF00291.25 KXZ54340.1 - 1.7e-76 257.4 6.5 2.7e-76 256.8 6.2 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXZ54340.1 - 3.9e-15 55.4 0.0 5.9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase DUF4761 PF15958.5 KXZ54340.1 - 0.072 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) HlyD_D4 PF16572.5 KXZ54340.1 - 0.12 12.3 0.0 0.46 10.4 0.0 2.0 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Peptidase_M3 PF01432.20 KXZ54341.1 - 4.5e-56 191.0 0.0 3e-55 188.3 0.0 1.8 1 1 1 2 2 2 1 Peptidase family M3 TFIIS_M PF07500.14 KXZ54341.1 - 9.1e-27 93.8 0.1 1.6e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TPH PF13868.6 KXZ54342.1 - 0.00035 19.2 132.1 0.00035 19.2 132.1 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain NAP PF00956.18 KXZ54343.1 - 6.7e-67 225.5 1.8 1.2e-66 224.7 1.8 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Prp19 PF08606.11 KXZ54344.1 - 2.3e-33 114.0 0.9 4.1e-33 113.2 0.9 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KXZ54344.1 - 1.3e-19 70.1 6.6 0.00018 22.2 0.0 7.4 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ54344.1 - 4.6e-10 39.7 0.0 0.021 15.1 0.0 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 KXZ54344.1 - 0.0028 17.4 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KXZ54344.1 - 0.074 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 U-box domain TMF_TATA_bd PF12325.8 KXZ54344.1 - 0.25 11.6 0.7 0.44 10.8 0.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding URO-D PF01208.17 KXZ54347.1 - 9.4e-104 347.3 0.0 1.1e-103 347.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Guanylate_cyc PF00211.20 KXZ54348.1 - 6.4e-56 188.9 0.0 1.1e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kinesin PF00225.23 KXZ54349.1 - 2.7e-100 335.6 0.1 3.5e-100 335.2 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ54349.1 - 6.8e-24 84.5 0.0 1.6e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding FliT PF05400.13 KXZ54349.1 - 6.3 7.7 10.7 1.3 9.8 2.1 3.6 3 1 0 3 3 3 0 Flagellar protein FliT PSII_Pbs27 PF13326.6 KXZ54350.1 - 6.8e-23 81.6 0.3 7.4e-23 81.4 0.3 1.0 1 0 0 1 1 1 1 Photosystem II Pbs27 TipAS PF07739.13 KXZ54350.1 - 0.089 13.3 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain RPN6_N PF18055.1 KXZ54350.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain FSA_C PF10479.9 KXZ54351.1 - 3.2 5.8 4.8 4.3 5.3 4.8 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus tRNA-synt_2 PF00152.20 KXZ54353.1 - 4.2e-80 269.1 0.0 5.6e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 KXZ54353.1 - 9e-17 61.1 0.1 1.5e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 KXZ54353.1 - 8.2e-14 51.4 0.0 1.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXZ54353.1 - 1.7e-05 24.5 0.1 0.015 14.8 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Metallophos PF00149.28 KXZ54354.1 - 3.1e-35 122.5 0.3 4.8e-35 121.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ54354.1 - 0.00061 20.0 0.0 0.00099 19.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 KXZ54354.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ribosomal_L24e PF01246.20 KXZ54355.1 - 1.6e-26 92.3 0.5 1.6e-26 92.3 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Spore_coat_CotO PF14153.6 KXZ54355.1 - 0.04 13.9 9.1 0.056 13.4 9.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO AlphaC_C PF17480.2 KXZ54355.1 - 0.095 12.7 1.4 0.14 12.2 1.4 1.2 1 0 0 1 1 1 0 AlphaC C-terminal DDHD PF02862.17 KXZ54355.1 - 0.75 9.9 3.9 0.91 9.6 3.9 1.0 1 0 0 1 1 1 0 DDHD domain GATase_7 PF13537.6 KXZ54357.1 - 7.9e-10 38.7 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXZ54357.1 - 3.4e-07 30.5 0.0 1.3e-06 28.7 0.0 2.0 3 0 0 3 3 3 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXZ54357.1 - 6.6e-06 25.7 0.0 7.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Aluminium induced protein DUF719 PF05334.13 KXZ54357.1 - 0.39 10.9 3.3 0.81 9.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Roughex PF06020.11 KXZ54357.1 - 0.88 8.6 2.9 1.5 7.8 2.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Pkinase PF00069.25 KXZ54358.1 - 3.3e-68 229.9 0.0 4.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54358.1 - 3.6e-43 147.7 0.0 4.8e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ54358.1 - 0.00028 19.8 0.0 0.00052 18.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ54358.1 - 0.0034 17.3 0.1 0.0034 17.3 0.1 3.8 3 2 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 KXZ54358.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ54358.1 - 0.2 10.9 0.0 3.2 7.0 0.0 2.3 2 1 0 2 2 2 0 Kinase-like ACT PF01842.25 KXZ54359.1 - 1.3e-10 40.9 0.1 0.0063 16.3 0.1 5.1 5 0 0 5 5 5 3 ACT domain ACT_6 PF13740.6 KXZ54359.1 - 0.00016 21.6 0.7 0.00044 20.2 0.1 2.0 2 0 0 2 2 2 1 ACT domain Pkinase_Tyr PF07714.17 KXZ54361.1 - 4.1e-40 137.7 0.0 8.7e-39 133.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ54361.1 - 3e-37 128.4 0.0 7.6e-37 127.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ54361.1 - 0.00026 21.0 1.4 0.0018 18.2 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ54361.1 - 0.00089 18.1 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KXZ54361.1 - 0.037 13.0 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain TRP PF06011.12 KXZ54362.1 - 0.00015 20.7 4.5 0.0013 17.5 0.1 2.4 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel MSC PF09402.10 KXZ54362.1 - 0.19 11.1 0.4 0.4 10.1 0.4 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Pkinase PF00069.25 KXZ54363.1 - 0.24 10.7 0.0 0.4 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain CCDC-167 PF15188.6 KXZ54364.1 - 0.005 17.1 15.3 0.0085 16.4 15.3 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Cob_adeno_trans PF01923.18 KXZ54364.1 - 0.015 15.4 0.9 0.024 14.8 0.9 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3584 PF12128.8 KXZ54364.1 - 0.028 11.9 5.5 0.036 11.6 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.14 KXZ54364.1 - 0.21 11.9 5.5 0.31 11.4 5.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YabA PF06156.13 KXZ54364.1 - 1 10.0 6.6 2 9.1 6.6 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Prefoldin_2 PF01920.20 KXZ54364.1 - 3.2 7.8 16.6 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit FapA PF03961.13 KXZ54364.1 - 3.6 6.1 8.7 4.7 5.7 8.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPP_enzyme_N PF02776.18 KXZ54365.1 - 4.3e-26 91.5 0.1 1.9e-25 89.5 0.1 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF2344 PF10105.9 KXZ54366.1 - 1.4e-13 51.1 0.0 2.5e-13 50.2 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) NIF PF03031.18 KXZ54367.1 - 2.1e-52 177.1 0.0 2.6e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CENP-B_dimeris PF09026.10 KXZ54367.1 - 0.8 10.1 4.9 0.73 10.3 1.4 2.7 2 1 0 2 2 2 0 Centromere protein B dimerisation domain S6PP PF05116.13 KXZ54368.1 - 5.8e-19 68.6 0.0 1.8e-08 34.2 0.0 4.2 5 0 0 5 5 5 3 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 KXZ54368.1 - 1.9e-06 27.8 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Noc2 PF03715.13 KXZ54369.1 - 1.4e-94 316.8 0.0 1.8e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 Noc2p family zf-CCCH PF00642.24 KXZ54370.1 - 6.1e-05 22.8 2.9 6.1e-05 22.8 2.9 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KXZ54370.1 - 0.00031 20.5 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KXZ54370.1 - 0.02 15.0 4.9 0.036 14.1 4.9 1.5 1 0 0 1 1 1 0 Zinc finger domain Gamma_PGA_hydro PF05908.11 KXZ54370.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase PRP38_assoc PF12871.7 KXZ54370.1 - 0.34 11.5 39.0 0.55 10.9 39.0 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term ChaB PF06150.12 KXZ54370.1 - 2.3 8.9 6.8 5.1 7.8 1.3 2.7 2 1 0 2 2 2 0 ChaB Ank_2 PF12796.7 KXZ54371.1 - 2.3e-06 28.1 0.0 0.0072 16.9 0.0 3.5 2 1 2 4 4 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54371.1 - 6.8e-06 26.5 0.4 0.064 13.9 0.0 4.1 3 2 1 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54371.1 - 0.00011 22.4 0.1 3.1 8.7 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KXZ54371.1 - 0.043 14.1 6.1 3.8 7.9 0.0 4.3 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ54371.1 - 0.39 11.3 2.4 68 4.2 0.1 4.0 4 0 0 4 4 4 0 Ankyrin repeat Sec7 PF01369.20 KXZ54372.1 - 2.8e-72 242.2 0.0 4.8e-72 241.5 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXZ54372.1 - 6.5e-41 139.9 0.5 2.2e-39 134.9 0.0 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXZ54372.1 - 5.8e-32 109.4 1.0 6.1e-31 106.1 0.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 KXZ54372.1 - 3.3e-24 85.5 3.6 3.2e-23 82.3 0.2 3.5 3 2 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KXZ54372.1 - 1.2e-06 27.1 0.0 2.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of Mon2 protein MMS19_N PF14500.6 KXZ54372.1 - 0.11 12.1 3.1 0.087 12.4 0.4 2.2 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II zf-MYND PF01753.18 KXZ54373.1 - 2.8e-11 43.3 5.5 5.3e-11 42.4 5.5 1.4 1 0 0 1 1 1 1 MYND finger Lant_dehydr_N PF04738.13 KXZ54373.1 - 0.024 12.8 0.2 0.035 12.2 0.2 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus CAP_N PF01213.19 KXZ54373.1 - 0.46 9.9 2.1 1.7 8.0 0.5 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MSP PF01716.18 KXZ54374.1 - 1.6e-98 328.7 0.5 2e-98 328.4 0.5 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide RskA PF10099.9 KXZ54374.1 - 0.29 11.4 4.7 0.57 10.5 4.7 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Choline_transpo PF04515.12 KXZ54375.1 - 0.0026 17.0 3.4 0.0026 17.0 3.4 1.4 1 1 0 1 1 1 1 Plasma-membrane choline transporter Popeye PF04831.13 KXZ54375.1 - 3 8.0 7.3 0.73 10.0 3.9 1.7 1 1 1 2 2 2 0 Popeye protein conserved region PG_binding_1 PF01471.18 KXZ54376.1 - 6.2e-16 58.4 0.0 1.3e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Hydrolase_4 PF12146.8 KXZ54377.1 - 3.3e-31 108.4 0.2 4.4e-29 101.4 0.2 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ54377.1 - 3.1e-11 43.4 0.0 2e-10 40.8 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ54377.1 - 5.2e-08 33.8 8.2 5.2e-08 33.8 8.2 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KXZ54377.1 - 2.6e-05 24.0 0.0 4.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXZ54377.1 - 3.3e-05 23.5 0.0 0.00013 21.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_8 PF06259.12 KXZ54377.1 - 0.0047 16.6 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Thioesterase PF00975.20 KXZ54377.1 - 0.0053 16.9 0.4 0.0098 16.0 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 KXZ54377.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 KXZ54377.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KXZ54377.1 - 0.27 10.9 0.0 0.42 10.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Metal_resist PF13801.6 KXZ54378.1 - 0.0036 17.5 1.2 0.0036 17.5 1.2 2.2 2 1 1 3 3 3 1 Heavy-metal resistance CDC45 PF02724.14 KXZ54378.1 - 0.15 10.3 0.0 0.19 10.0 0.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Ion_trans PF00520.31 KXZ54379.1 - 1.1e-06 28.0 0.3 1.3e-06 27.8 0.3 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXZ54379.1 - 0.054 12.2 1.2 0.065 11.9 1.2 1.1 1 0 0 1 1 1 0 Polycystin cation channel Y_phosphatase PF00102.27 KXZ54380.1 - 2.1e-57 194.4 0.0 7.7e-29 100.9 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KXZ54380.1 - 1e-05 25.4 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXZ54380.1 - 7.4e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KXZ54380.1 - 0.0049 17.0 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF4106 PF13388.6 KXZ54381.1 - 2.5 7.3 4.2 3.6 6.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) LRR_8 PF13855.6 KXZ54381.1 - 3.2 7.6 13.0 2.8 7.8 0.1 4.9 7 0 0 7 7 7 0 Leucine rich repeat YliH PF10799.8 KXZ54382.1 - 0.064 13.2 0.5 0.17 11.8 0.5 1.7 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) AA_permease_2 PF13520.6 KXZ54383.1 - 9.6e-44 149.9 26.4 1.3e-43 149.4 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXZ54383.1 - 3.2e-07 29.3 37.6 6e-07 28.4 37.6 1.4 1 1 0 1 1 1 1 Amino acid permease DUF4752 PF15944.5 KXZ54383.1 - 4.6 7.4 5.9 3.1 7.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) SBP PF03110.14 KXZ54384.1 - 8.6e-30 102.9 13.1 1.8e-29 101.8 13.1 1.6 1 0 0 1 1 1 1 SBP domain Ank_2 PF12796.7 KXZ54384.1 - 7.7e-05 23.2 0.1 0.00035 21.1 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54384.1 - 0.00013 22.5 0.8 0.099 13.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54384.1 - 0.00019 21.6 3.8 1 10.1 0.1 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXZ54384.1 - 0.0013 19.1 3.4 4.7 7.8 0.1 4.9 4 0 0 4 4 4 1 Ankyrin repeat DUF3602 PF12223.8 KXZ54384.1 - 1.3 9.7 5.0 3.3 8.4 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) PSD5 PF07637.11 KXZ54385.1 - 0.17 12.2 2.4 0.24 11.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) ADH_zinc_N_2 PF13602.6 KXZ54386.1 - 4.3e-12 47.2 0.2 7.3e-12 46.5 0.2 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXZ54386.1 - 5.3e-09 35.9 0.0 1.3e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SNF2_N PF00176.23 KXZ54387.1 - 1.4e-55 188.5 0.0 4.2e-55 186.9 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_UBOX PF13445.6 KXZ54387.1 - 1.1e-08 34.9 0.8 1.9e-08 34.2 0.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXZ54387.1 - 8.2e-07 28.8 6.0 1.4e-06 28.0 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ54387.1 - 3.2e-06 27.4 5.9 7.4e-06 26.2 5.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ54387.1 - 1.2e-05 25.0 2.7 1.2e-05 25.0 2.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ54387.1 - 2.2e-05 24.2 6.5 5.3e-05 23.0 6.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ54387.1 - 6e-05 22.9 4.6 0.00019 21.3 4.7 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXZ54387.1 - 0.00075 19.6 3.6 0.0034 17.5 3.9 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Helicase_C PF00271.31 KXZ54387.1 - 0.00076 19.8 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KXZ54387.1 - 0.0025 17.6 6.1 0.048 13.5 6.1 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXZ54387.1 - 0.032 14.0 3.6 0.069 12.9 3.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KXZ54387.1 - 0.29 10.9 2.3 0.66 9.8 2.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KXZ54387.1 - 0.89 9.9 3.1 2.2 8.6 3.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain CP12 PF02672.15 KXZ54387.1 - 1.6 9.6 5.4 12 6.7 5.4 2.7 1 0 0 1 1 1 0 CP12 domain U-box PF04564.15 KXZ54388.1 - 3.7e-11 43.1 0.0 7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXZ54388.1 - 0.23 11.3 0.1 0.44 10.4 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FHA PF00498.26 KXZ54389.1 - 2.7e-14 53.2 0.0 1.3e-13 51.1 0.0 2.0 1 1 1 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KXZ54389.1 - 0.00018 21.8 0.1 0.002 18.4 0.1 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain BTB PF00651.31 KXZ54390.1 - 4e-15 56.0 0.0 6.5e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain SBBP PF06739.11 KXZ54390.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-propeller repeat Frankia_peptide PF14407.6 KXZ54392.1 - 0.024 14.6 0.5 0.43 10.6 0.1 2.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PAP1 PF08601.10 KXZ54392.1 - 0.16 11.7 6.3 0.21 11.3 6.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Filament_head PF04732.14 KXZ54392.1 - 3.6 8.5 14.2 1.5 9.8 8.6 2.6 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region PAN_4 PF14295.6 KXZ54393.1 - 3.4e-05 23.7 8.4 0.0036 17.2 2.2 2.5 2 0 0 2 2 2 2 PAN domain Pro_isomerase PF00160.21 KXZ54393.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M50 PF02163.22 KXZ54394.1 - 1.9e-07 30.6 5.1 0.0025 17.1 0.4 2.3 1 1 1 2 2 2 2 Peptidase family M50 Peptidase_M50B PF13398.6 KXZ54394.1 - 0.07 12.8 19.8 0.13 11.9 18.1 2.1 1 1 0 1 1 1 0 Peptidase M50B-like Ribosomal_L27A PF00828.19 KXZ54395.1 - 3.1e-24 86.1 0.3 4.2e-24 85.6 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 KXZ54395.1 - 0.11 12.6 1.7 0.22 11.6 1.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5026) Mpv17_PMP22 PF04117.12 KXZ54396.1 - 3.6e-19 68.8 0.8 6.1e-19 68.0 0.8 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF218 PF02698.17 KXZ54397.1 - 0.0013 18.8 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Glyco_hydro_16 PF00722.21 KXZ54398.1 - 6.6e-09 35.5 0.1 1.5e-08 34.3 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Aa_trans PF01490.18 KXZ54399.1 - 5.2e-55 186.8 4.2 8.6e-55 186.1 4.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein WD40 PF00400.32 KXZ54400.1 - 2e-38 129.7 13.1 1.1e-09 38.7 1.0 5.8 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ54400.1 - 5.3e-16 58.7 0.0 1.1e-05 25.6 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ54400.1 - 5.2e-06 26.5 0.0 0.0006 19.8 0.0 2.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXZ54400.1 - 5.3e-05 22.1 1.9 0.08 11.6 0.0 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXZ54400.1 - 0.0013 17.8 0.0 0.068 12.1 0.0 2.8 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXZ54400.1 - 0.0087 14.1 0.0 0.47 8.4 0.0 2.1 2 0 0 2 2 2 2 IKI3 family Frtz PF11768.8 KXZ54400.1 - 0.11 10.8 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KXZ54400.1 - 0.17 11.2 0.0 8.5 5.6 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain Radical_SAM PF04055.21 KXZ54401.1 - 1.1e-20 74.6 0.0 1.9e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 KXZ54401.1 - 9.5e-10 38.9 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family PsaN PF05479.11 KXZ54402.1 - 0.005 17.0 0.1 0.0071 16.5 0.1 1.2 1 0 0 1 1 1 1 Photosystem I reaction centre subunit N (PSAN or PSI-N) NIF PF03031.18 KXZ54403.1 - 5.9e-39 133.3 0.0 2e-38 131.6 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Put_Phosphatase PF06888.12 KXZ54403.1 - 1.3e-31 109.8 0.0 1.3e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 Putative Phosphatase zf-C3HC4_4 PF15227.6 KXZ54403.1 - 6.1e-08 32.7 1.9 6.1e-08 32.7 1.9 2.8 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXZ54403.1 - 2.5e-07 30.6 3.3 2.5e-07 30.6 3.3 2.3 2 0 0 2 2 2 1 RING-type zinc-finger HAD PF12710.7 KXZ54403.1 - 8.4e-07 29.6 4.3 0.27 11.6 0.1 4.8 3 2 1 4 4 4 3 haloacid dehalogenase-like hydrolase zf-C3HC4 PF00097.25 KXZ54403.1 - 3.2e-06 26.9 2.5 3.2e-06 26.9 2.5 3.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ54403.1 - 7.4e-06 25.7 4.3 7.4e-06 25.7 4.3 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ54403.1 - 0.00025 20.9 3.3 0.00025 20.9 3.3 4.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ54403.1 - 0.0004 20.7 3.9 0.0004 20.7 3.9 3.7 4 0 0 4 4 3 1 Ring finger domain zf-Nse PF11789.8 KXZ54403.1 - 0.084 12.7 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Phage_CI_repr PF07022.13 KXZ54403.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DUF1644 PF07800.12 KXZ54403.1 - 0.21 11.7 6.0 1 9.4 6.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-RING_11 PF17123.5 KXZ54403.1 - 6.5 6.6 7.3 4.7 7.0 4.8 2.1 2 0 0 2 2 2 0 RING-like zinc finger DUF829 PF05705.14 KXZ54404.1 - 1.4e-06 28.4 0.1 0.036 13.9 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Ank_4 PF13637.6 KXZ54405.1 - 3e-12 46.8 3.6 0.062 13.9 0.3 6.6 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ54405.1 - 2.6e-09 37.5 0.0 0.14 12.8 0.0 4.6 3 1 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54405.1 - 8e-06 25.8 3.1 37 5.3 0.0 7.9 8 1 1 9 9 9 1 Ankyrin repeat Whib PF02467.16 KXZ54405.1 - 0.53 10.9 5.0 3 8.5 0.3 3.5 3 0 0 3 3 3 0 Transcription factor WhiB AhpC-TSA PF00578.21 KXZ54406.1 - 9.6e-35 119.2 0.0 1.4e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ54406.1 - 9.5e-14 51.3 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXZ54406.1 - 2.2e-13 49.8 0.0 3.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KXZ54406.1 - 0.083 12.8 0.1 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 SCO1/SenC Pro_isomerase PF00160.21 KXZ54408.1 - 4.9e-34 117.9 0.0 5.6e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Amidase PF01425.21 KXZ54409.1 - 1.1e-17 64.1 15.1 3.2e-17 62.6 15.1 1.7 1 0 0 1 1 1 1 Amidase TPR_1 PF00515.28 KXZ54409.1 - 7.8e-17 60.3 5.5 3.8e-05 23.3 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ54409.1 - 5.7e-14 51.0 8.3 0.0018 18.2 0.3 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ54409.1 - 2.9e-07 30.2 4.4 0.039 14.2 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ54409.1 - 8.3e-06 25.4 10.0 6.2e-05 22.6 0.2 3.3 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 KXZ54409.1 - 6.3e-05 23.2 4.1 0.00026 21.2 0.5 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ54409.1 - 7.1e-05 22.8 6.2 0.0019 18.2 0.5 3.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KXZ54409.1 - 0.00024 21.5 0.9 1.3 9.9 0.1 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ54409.1 - 0.008 16.0 9.4 1.1 9.2 0.5 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ54409.1 - 0.017 15.9 0.0 0.017 15.9 0.0 6.0 4 2 1 5 5 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ54409.1 - 0.023 15.0 1.5 0.056 13.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PLN_propep PF16485.5 KXZ54409.1 - 0.54 10.0 2.1 0.6 9.9 0.8 1.7 2 0 0 2 2 2 0 Protealysin propeptide DUF4499 PF14934.6 KXZ54410.1 - 8.3e-15 54.9 0.7 9.8e-15 54.7 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) QCR10 PF09796.9 KXZ54410.1 - 1.1 9.4 4.7 1.2 9.2 3.7 1.8 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) ECH_1 PF00378.20 KXZ54411.1 - 2.2e-33 115.6 0.0 2.7e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXZ54411.1 - 4.1e-15 56.1 0.0 5.5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_tranf_2_3 PF13641.6 KXZ54412.1 - 7.3e-06 26.0 0.1 2.7e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 KXZ54412.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Glycos_transf_2 PF00535.26 KXZ54412.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Pkinase PF00069.25 KXZ54413.1 - 7.5e-23 81.2 0.0 1.2e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ubiquitin PF00240.23 KXZ54413.1 - 7.3e-22 76.9 0.0 1.4e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Pkinase_Tyr PF07714.17 KXZ54413.1 - 3e-15 56.2 0.0 4.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rad60-SLD PF11976.8 KXZ54413.1 - 7.1e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Kinase-like PF14531.6 KXZ54413.1 - 0.00026 20.4 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ubiquitin_2 PF14560.6 KXZ54413.1 - 0.0054 17.2 0.1 0.013 15.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Kdo PF06293.14 KXZ54413.1 - 0.22 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_tranf_2_3 PF13641.6 KXZ54416.1 - 1.4e-05 25.1 0.3 7.6e-05 22.7 0.2 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 KXZ54416.1 - 0.0096 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family Glycos_transf_2 PF00535.26 KXZ54416.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KXZ54416.1 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Pkinase PF00069.25 KXZ54417.1 - 5.6e-22 78.4 0.0 4.5e-17 62.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54417.1 - 6.4e-08 32.2 0.0 2.8e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase TFIIA PF03153.13 KXZ54417.1 - 0.87 9.5 8.0 1.2 9.0 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BACK PF07707.15 KXZ54419.1 - 0.0003 20.8 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Inhibitor_I68 PF10468.9 KXZ54419.1 - 0.073 13.5 3.9 0.47 10.9 0.0 3.1 2 1 1 3 3 3 0 Carboxypeptidase inhibitor I68 zf-3CxxC_2 PF17180.4 KXZ54420.1 - 1.8e-22 79.8 6.5 2.2e-22 79.6 6.5 1.1 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC PF13695.6 KXZ54420.1 - 6.9e-05 23.3 12.8 0.0021 18.5 12.8 2.4 1 1 0 1 1 1 1 Zinc-binding domain UPF0515 PF15135.6 KXZ54420.1 - 0.00079 18.9 3.6 0.00084 18.8 3.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 Zn_clus PF00172.18 KXZ54420.1 - 0.034 14.3 0.1 0.034 14.3 0.1 2.6 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KXZ54421.1 - 4.6e-43 147.5 0.0 2e-41 142.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54421.1 - 1.6e-40 139.1 0.0 3e-39 134.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ54421.1 - 0.0081 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF1679 PF07914.11 KXZ54421.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.23 KXZ54421.1 - 0.044 13.7 0.2 0.044 13.7 0.2 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ54421.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain tRNA-synt_His PF13393.6 KXZ54423.1 - 1.5e-46 159.1 0.0 2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KXZ54423.1 - 9.9e-12 44.9 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXZ54423.1 - 1e-09 38.6 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 KXZ54423.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Pkinase PF00069.25 KXZ54424.1 - 8.8e-62 208.8 0.0 1.1e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54424.1 - 5.3e-35 120.9 0.0 7.7e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ54424.1 - 3.8e-07 29.3 0.0 7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ54424.1 - 6.3e-06 25.7 0.1 4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXZ54424.1 - 0.0074 16.2 0.2 0.028 14.4 0.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 KXZ54426.1 - 1.5e-61 205.0 18.1 4.5e-16 59.2 1.7 5.1 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54426.1 - 1.3e-48 157.3 6.8 6.8e-05 23.0 0.0 9.9 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KXZ54426.1 - 3.2e-47 158.3 6.2 2.1e-08 34.5 0.2 7.9 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ54426.1 - 6.8e-47 156.9 19.1 2.7e-10 40.3 0.0 8.3 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KXZ54426.1 - 1.8e-44 148.3 25.7 0.00011 22.5 0.0 9.0 8 1 1 9 9 9 8 Ankyrin repeat DUF4129 PF13559.6 KXZ54426.1 - 1.4 9.2 7.0 3.8 7.9 0.8 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4129) YccV-like PF08755.11 KXZ54428.1 - 3.2e-15 56.4 0.0 8e-15 55.1 0.0 1.7 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like UVR PF02151.19 KXZ54428.1 - 2.9e-06 26.8 5.4 2.9e-06 26.8 5.4 2.4 2 0 0 2 2 2 1 UvrB/uvrC motif Glyco_tranf_2_3 PF13641.6 KXZ54429.1 - 8.8e-07 29.0 0.0 2.4e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 KXZ54429.1 - 0.00015 21.5 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family Glycos_transf_2 PF00535.26 KXZ54429.1 - 0.00042 20.2 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Kazal_1 PF00050.21 KXZ54430.1 - 2.9e-71 235.3 119.0 4.5e-08 33.0 5.6 11.7 5 4 6 11 11 11 11 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KXZ54430.1 - 9.5e-59 195.3 144.2 1.8e-06 28.0 6.0 11.5 11 0 0 11 11 11 11 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KXZ54431.1 - 6.5e-71 234.2 120.1 1.9e-08 34.2 4.3 11.7 6 5 5 11 11 11 11 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KXZ54431.1 - 9.7e-58 192.1 144.6 1.8e-06 28.0 6.0 11.5 11 0 0 11 11 11 11 Kazal-type serine protease inhibitor domain KASH_CCD PF14662.6 KXZ54433.1 - 0.0046 16.8 8.4 0.0061 16.4 8.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 KXZ54433.1 - 0.015 15.5 15.6 0.08 13.2 4.8 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 KXZ54433.1 - 0.017 15.3 8.6 0.067 13.4 2.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DASH_Dam1 PF08653.10 KXZ54433.1 - 0.14 11.9 0.4 0.56 10.1 0.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 YabA PF06156.13 KXZ54433.1 - 0.28 11.8 3.3 0.38 11.4 0.4 2.1 2 0 0 2 2 2 0 Initiation control protein YabA LPP PF04728.13 KXZ54433.1 - 0.37 11.2 3.0 0.2 12.1 0.6 1.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Lzipper-MIP1 PF14389.6 KXZ54433.1 - 0.47 10.8 11.8 0.45 10.9 3.2 3.1 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 UPF0449 PF15136.6 KXZ54433.1 - 0.49 10.9 5.7 0.36 11.3 3.4 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Spc29 PF17082.5 KXZ54433.1 - 0.59 9.9 5.9 1.3 8.8 0.9 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 UPF0242 PF06785.11 KXZ54433.1 - 1.1 9.3 13.3 3.8 7.6 2.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KXZ54433.1 - 3.3 7.0 6.7 15 4.8 6.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 KXZ54433.1 - 3.7 7.9 7.7 4.7 7.6 6.9 1.6 1 1 0 1 1 1 0 YlqD protein Spc7 PF08317.11 KXZ54433.1 - 3.8 6.3 12.5 6.4 5.6 4.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Troponin PF00992.20 KXZ54433.1 - 4.7 7.5 10.6 9.7 6.5 10.6 1.5 1 1 0 1 1 1 0 Troponin ZapB PF06005.12 KXZ54433.1 - 8.8 6.8 15.4 0.38 11.2 6.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Med25_VWA PF11265.8 KXZ54434.1 - 5e-05 23.2 0.0 0.00018 21.4 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit 25 von Willebrand factor type A CCDC50_N PF15295.6 KXZ54435.1 - 0.003 17.7 5.1 0.0034 17.5 5.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus NuDC PF16273.5 KXZ54435.1 - 1.9 9.1 10.8 4.6 7.8 3.3 2.2 1 1 1 2 2 2 0 Nuclear distribution C domain Nif11 PF07862.11 KXZ54435.1 - 2.7 8.4 9.0 9.2 6.7 0.6 2.4 1 1 1 2 2 2 0 Nif11 domain RabGAP-TBC PF00566.18 KXZ54436.1 - 7.4e-44 150.0 0.0 9.4e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3275 PF11679.8 KXZ54436.1 - 0.16 11.9 6.5 0.41 10.6 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Pkinase_fungal PF17667.1 KXZ54438.1 - 5.7e-07 28.7 0.0 7.8e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KXZ54438.1 - 7.7e-05 22.2 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXZ54438.1 - 0.00053 20.0 0.2 0.0055 16.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family GTP_EFTU PF00009.27 KXZ54439.1 - 1e-46 158.9 0.0 1.5e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXZ54439.1 - 1.1e-24 86.3 0.0 2.4e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFTUD2 PF16004.5 KXZ54439.1 - 5.9e-23 81.8 2.2 1e-22 81.0 2.2 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KXZ54439.1 - 4.9e-20 71.5 0.0 2e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KXZ54439.1 - 4.2e-14 52.7 0.1 1.1e-13 51.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXZ54439.1 - 1.2e-05 25.3 0.0 6.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXZ54439.1 - 0.00021 21.3 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXZ54439.1 - 0.0019 17.7 0.0 0.058 12.8 0.0 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 KXZ54439.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KXZ54439.1 - 0.21 11.8 0.0 1.3 9.2 0.1 2.0 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TPH PF13868.6 KXZ54441.1 - 2e-55 187.7 146.8 2e-55 187.7 146.8 2.5 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain WSC PF01822.19 KXZ54442.1 - 1.2e-07 31.8 0.1 1.9e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 WSC domain LCM PF04072.14 KXZ54443.1 - 1.4e-35 122.9 0.0 1.9e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF3880 PF12996.7 KXZ54443.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) HATPase_c_3 PF13589.6 KXZ54445.1 - 5e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXZ54445.1 - 0.00011 22.7 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4407 PF14362.6 KXZ54446.1 - 0.29 10.4 2.0 0.49 9.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3707 PF12499.8 KXZ54448.1 - 3.1e-49 167.2 22.2 3.7e-26 92.4 7.7 2.1 2 0 0 2 2 2 2 Pherophorin Alg14 PF08660.11 KXZ54449.1 - 7e-45 153.1 0.2 1.8e-42 145.2 0.2 2.0 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Oxysterol_BP PF01237.18 KXZ54450.1 - 5.5e-46 157.1 0.0 3.7e-38 131.3 0.0 2.3 2 1 0 2 2 2 2 Oxysterol-binding protein Cript PF10235.9 KXZ54452.1 - 1.3e-28 99.4 10.4 1.3e-28 99.4 10.4 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DUF1272 PF06906.11 KXZ54452.1 - 0.018 15.1 8.0 0.043 13.9 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 KXZ54452.1 - 0.046 13.7 14.7 1.1 9.3 10.6 2.8 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KXZ54452.1 - 0.19 12.1 14.8 0.27 11.6 3.7 3.2 2 1 1 3 3 3 0 C1 domain Zn_ribbon_17 PF17120.5 KXZ54452.1 - 0.35 10.5 9.3 6.8 6.4 5.5 2.5 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zinc_ribbon_15 PF17032.5 KXZ54452.1 - 0.4 11.5 13.1 0.47 11.2 9.6 2.4 2 1 0 2 2 2 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 KXZ54452.1 - 0.53 10.1 0.0 0.53 10.1 0.0 3.7 3 1 1 4 4 4 0 zinc-ribbon domain PLATZ PF04640.14 KXZ54452.1 - 3.9 8.2 12.8 3.6 8.3 3.6 3.0 1 1 2 3 3 3 0 PLATZ transcription factor LIM PF00412.22 KXZ54452.1 - 5.8 7.2 14.8 21 5.4 0.4 3.4 3 1 0 3 3 3 0 LIM domain C1_1 PF00130.22 KXZ54452.1 - 6.2 6.8 15.3 5.1 7.1 4.8 3.2 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPRY PF00622.28 KXZ54453.1 - 5.7e-13 49.0 0.4 2.9e-06 27.4 0.1 2.2 2 0 0 2 2 2 2 SPRY domain NSP10 PF09401.10 KXZ54453.1 - 0.13 12.3 0.1 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 RNA synthesis protein NSP10 Suf PF05843.14 KXZ54454.1 - 2.1e-12 47.7 0.3 2.6e-06 27.7 0.4 2.6 2 1 0 2 2 2 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KXZ54454.1 - 5.7e-06 25.7 0.1 0.00022 20.4 0.0 3.4 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KXZ54454.1 - 0.0028 18.3 0.3 0.03 15.1 0.5 9.1 5 3 4 9 9 9 2 Tetratricopeptide repeat APG17 PF04108.12 KXZ54454.1 - 0.2 10.7 0.9 27 3.7 0.0 3.1 3 0 0 3 3 3 0 Autophagy protein Apg17 APH PF01636.23 KXZ54456.1 - 4.3e-16 59.6 1.8 7.4e-16 58.8 1.8 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family ApoLp-III PF07464.11 KXZ54457.1 - 0.0049 17.0 11.1 0.063 13.4 8.2 2.9 3 1 0 3 3 3 2 Apolipophorin-III precursor (apoLp-III) LON_substr_bdg PF02190.16 KXZ54459.1 - 2.7e-06 27.4 0.0 3.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain XPG_I PF00867.18 KXZ54461.1 - 1.1e-15 57.7 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region DUF2283 PF10049.9 KXZ54461.1 - 0.0018 18.4 0.0 0.0048 17.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) XPG_I_2 PF12813.7 KXZ54461.1 - 0.0035 16.8 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 KXZ54462.1 - 1.6e-15 57.2 0.0 3.3e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXZ54462.1 - 1e-10 42.0 0.0 1.9e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain zf-MYND PF01753.18 KXZ54463.1 - 5.6e-10 39.1 10.7 1.1e-09 38.2 10.7 1.5 1 0 0 1 1 1 1 MYND finger DUF5132 PF17195.4 KXZ54463.1 - 0.13 12.4 0.8 1.1 9.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) FoP_duplication PF13865.6 KXZ54463.1 - 6.4 7.4 6.4 19 5.9 6.4 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Reticulon PF02453.17 KXZ54464.1 - 3.5e-11 43.3 0.2 3.8e-11 43.2 0.2 1.0 1 0 0 1 1 1 1 Reticulon HAD_2 PF13419.6 KXZ54465.1 - 1.1e-10 41.9 0.0 4.9e-07 30.0 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ54465.1 - 2.4e-09 37.8 0.1 4e-09 37.1 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ54465.1 - 4e-09 37.1 0.0 1.3e-08 35.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ54465.1 - 1.4e-07 31.5 0.1 2.7e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Ras PF00071.22 KXZ54466.1 - 1.9e-57 193.4 0.1 2.3e-57 193.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ54466.1 - 3.8e-34 117.5 0.1 5.7e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ54466.1 - 1.4e-14 53.9 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXZ54466.1 - 2.9e-08 33.8 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXZ54466.1 - 3.1e-07 30.0 0.0 3.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXZ54466.1 - 7.1e-07 29.0 0.1 2.7e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KXZ54466.1 - 0.00029 20.3 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXZ54466.1 - 0.00061 19.7 0.1 0.0027 17.6 0.1 1.9 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXZ54466.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KXZ54466.1 - 0.0015 17.9 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 KXZ54466.1 - 0.0042 16.8 0.4 0.093 12.5 0.2 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KXZ54466.1 - 0.009 15.5 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KXZ54466.1 - 0.012 15.4 0.2 0.018 14.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KXZ54466.1 - 0.012 15.3 0.1 0.042 13.4 0.1 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KXZ54466.1 - 0.015 15.2 0.1 0.029 14.3 0.1 1.5 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 KXZ54466.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KXZ54466.1 - 0.017 14.5 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KXZ54466.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DAP3 PF10236.9 KXZ54466.1 - 0.054 12.7 0.2 0.073 12.2 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KXZ54466.1 - 0.061 13.8 0.2 0.08 13.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 KXZ54466.1 - 0.069 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KXZ54466.1 - 0.081 13.1 0.1 0.69 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KXZ54466.1 - 0.082 12.1 1.0 0.32 10.1 0.3 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 KXZ54466.1 - 0.09 12.8 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXZ54466.1 - 0.098 13.1 0.2 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA helicase MCM PF00493.23 KXZ54466.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 KXZ54466.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Exostosin PF03016.15 KXZ54467.1 - 4.3e-54 183.8 0.0 6.4e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ54467.1 - 0.00033 21.0 16.5 0.00033 21.0 16.5 3.7 3 0 0 3 3 3 1 EGF-like domain I-EGF_1 PF18372.1 KXZ54467.1 - 0.024 14.7 8.4 0.066 13.3 8.4 1.8 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 DUF1295 PF06966.12 KXZ54468.1 - 1e-31 110.3 0.1 1.5e-31 109.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXZ54468.1 - 0.036 14.5 0.4 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXZ54468.1 - 0.056 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Phospholipid methyltransferase LRR_8 PF13855.6 KXZ54469.1 - 3.8e-14 52.2 7.4 1.5e-09 37.5 0.4 3.9 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KXZ54469.1 - 3.2e-13 49.6 1.2 7.5e-05 23.0 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ54469.1 - 0.0044 17.4 1.7 19 6.3 0.3 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat UPF0242 PF06785.11 KXZ54469.1 - 0.092 12.8 9.6 0.13 12.3 9.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GrpE PF01025.19 KXZ54469.1 - 0.34 10.5 9.3 0.5 10.0 9.3 1.2 1 0 0 1 1 1 0 GrpE LRR_6 PF13516.6 KXZ54469.1 - 0.37 11.0 1.1 59 4.1 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Fmp27 PF10344.9 KXZ54469.1 - 0.41 8.7 2.5 0.56 8.2 2.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Spc7 PF08317.11 KXZ54469.1 - 0.53 9.1 18.6 0.82 8.5 18.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KXZ54469.1 - 0.72 9.4 7.2 1 8.9 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 KXZ54469.1 - 2.2 7.5 17.0 3.7 6.8 17.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF572 PF04502.13 KXZ54469.1 - 5.6 6.5 11.7 8.5 5.9 11.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) IRK_C PF17655.1 KXZ54470.1 - 4.1e-53 179.6 0.0 2.1e-32 112.1 0.0 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KXZ54470.1 - 1.6e-13 50.6 0.0 2.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain eIF3_subunit PF08597.10 KXZ54471.1 - 9.2e-30 104.3 9.0 1.8e-29 103.4 9.0 1.5 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit THUMP PF02926.17 KXZ54471.1 - 0.024 14.7 0.7 0.039 14.0 0.4 1.5 1 1 0 1 1 1 0 THUMP domain Bac_surface_Ag PF01103.23 KXZ54472.1 - 8.5e-28 97.8 0.0 1.3e-24 87.3 0.0 2.1 1 1 0 1 1 1 1 Surface antigen Apidaecin PF00807.17 KXZ54473.1 - 0.018 15.1 0.1 0.086 13.0 0.1 2.2 1 0 0 1 1 1 0 Apidaecin RGS_DHEX PF18148.1 KXZ54473.1 - 0.021 15.0 0.3 5 7.3 0.0 3.0 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain LRS4 PF10422.9 KXZ54473.1 - 1.5 8.3 26.1 0.19 11.3 0.2 3.9 2 2 1 4 4 4 0 Monopolin complex subunit LRS4 DUF4055 PF13264.6 KXZ54473.1 - 8.9 6.5 14.4 0.09 12.9 2.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) ERCC4 PF02732.15 KXZ54474.1 - 4.7e-19 69.1 0.0 6.3e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 ERCC4 domain Flavokinase PF01687.17 KXZ54475.1 - 1e-29 103.1 0.0 1.4e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase HAD_2 PF13419.6 KXZ54475.1 - 5.1e-08 33.2 0.0 2.2e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ54475.1 - 3.8e-05 24.1 0.1 0.00028 21.2 0.0 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ54475.1 - 0.029 14.4 0.8 0.12 12.4 0.5 2.2 1 1 1 2 2 2 0 HAD-hyrolase-like Ligase_CoA PF00549.19 KXZ54475.1 - 0.19 11.6 0.1 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 CoA-ligase CLZ PF16526.5 KXZ54477.1 - 0.12 12.7 19.9 0.31 11.4 3.4 3.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5082 PF16888.5 KXZ54477.1 - 0.18 12.1 7.3 0.52 10.6 7.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 KXZ54477.1 - 0.28 10.0 27.7 0.027 13.4 15.0 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein MSC PF09402.10 KXZ54477.1 - 0.31 10.5 4.2 0.15 11.5 1.3 2.0 2 1 0 2 2 2 0 Man1-Src1p-C-terminal domain Syntaxin_2 PF14523.6 KXZ54477.1 - 0.32 11.4 6.5 0.079 13.3 2.0 2.4 3 0 0 3 3 3 0 Syntaxin-like protein DUF3461 PF11944.8 KXZ54477.1 - 1 9.5 4.9 2.6 8.2 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) FapA PF03961.13 KXZ54477.1 - 2.3 6.7 12.3 0.02 13.5 3.5 2.0 3 0 0 3 3 3 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 KXZ54477.1 - 3.3 7.8 8.7 4.2 7.4 3.4 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRS4 PF10422.9 KXZ54477.1 - 3.5 7.1 12.2 0.82 9.2 8.5 1.8 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 DUF948 PF06103.11 KXZ54477.1 - 5.9 7.2 11.1 1.9 8.8 3.5 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Csm1_N PF18504.1 KXZ54477.1 - 6.7 7.1 22.8 0.61 10.5 0.5 5.1 4 2 1 5 5 5 0 Csm1 N-terminal domain Nucleotid_trans PF03407.16 KXZ54479.1 - 0.072 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase BTB PF00651.31 KXZ54480.1 - 1.7e-12 47.6 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Dak1 PF02733.17 KXZ54481.1 - 1.1e-105 352.9 0.4 3.1e-105 351.5 0.4 1.7 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXZ54481.1 - 6.3e-38 130.4 17.4 6.3e-38 130.4 17.4 5.2 6 1 1 7 7 7 1 DAK2 domain FH2 PF02181.23 KXZ54482.1 - 9.5e-52 176.3 0.0 2.8e-51 174.8 0.0 1.7 1 1 0 1 1 1 1 Formin Homology 2 Domain MFS_1 PF07690.16 KXZ54483.1 - 5.4e-26 91.4 32.8 1.8e-20 73.2 16.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KXZ54484.1 - 0.038 14.6 0.0 3.2 8.4 0.0 3.1 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) zf-MYND PF01753.18 KXZ54485.1 - 8.1e-07 29.0 9.4 1.4e-06 28.2 9.4 1.5 1 0 0 1 1 1 1 MYND finger SDA1 PF05285.12 KXZ54485.1 - 0.014 14.8 2.2 0.014 14.8 2.2 1.0 1 0 0 1 1 1 0 SDA1 SelK_SelG PF10961.8 KXZ54485.1 - 0.19 12.3 0.4 0.36 11.5 0.4 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG WRNPLPNID PF15017.6 KXZ54485.1 - 1.1 10.1 14.8 1.8 9.5 14.8 1.3 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box CDC45 PF02724.14 KXZ54485.1 - 3.3 5.9 6.2 3.9 5.7 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.14 KXZ54485.1 - 7.5 5.1 7.7 9.1 4.8 7.7 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Transket_pyr PF02779.24 KXZ54487.1 - 1.5e-38 132.3 0.1 3.6e-38 131.0 0.1 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXZ54487.1 - 3e-33 114.3 0.0 7.9e-33 113.0 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF1664 PF07889.12 KXZ54487.1 - 4.4 7.4 9.4 0.91 9.6 0.8 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) BT1 PF03092.16 KXZ54488.1 - 2.7e-57 194.2 11.5 9.3e-56 189.1 11.5 2.1 1 1 0 1 1 1 1 BT1 family MFS_1_like PF12832.7 KXZ54488.1 - 0.014 14.2 0.2 0.021 13.7 0.2 1.3 1 0 0 1 1 1 0 MFS_1 like family DAO PF01266.24 KXZ54489.1 - 3.4e-43 148.6 11.3 2.1e-22 80.2 4.2 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXZ54489.1 - 1.9e-07 30.6 0.2 3.2e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXZ54489.1 - 1.7e-05 24.1 0.2 2.6e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXZ54489.1 - 3.2e-05 24.1 0.1 7e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXZ54489.1 - 9e-05 21.7 0.2 0.00019 20.6 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXZ54489.1 - 0.00011 21.5 0.1 0.00016 21.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXZ54489.1 - 0.0014 17.6 0.4 0.0019 17.2 0.4 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Mqo PF06039.15 KXZ54489.1 - 0.032 12.8 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) MCRA PF06100.11 KXZ54489.1 - 0.093 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 KXZ54489.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXZ54489.1 - 0.14 11.4 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXZ54489.1 - 0.21 10.6 0.5 0.29 10.2 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXZ54489.1 - 0.22 10.2 0.1 0.3 9.7 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXZ54489.1 - 0.29 10.3 0.2 0.42 9.8 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 KXZ54490.1 - 8e-21 75.0 0.0 1e-20 74.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KXZ54490.1 - 0.00043 20.7 0.2 0.0009 19.7 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXZ54490.1 - 0.0039 17.5 0.0 0.017 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KXZ54490.1 - 0.0098 15.7 0.0 0.61 9.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXZ54490.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXZ54490.1 - 0.044 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KXZ54490.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KXZ54490.1 - 0.096 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase IstB_IS21 PF01695.17 KXZ54490.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KXZ54490.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KXZ54490.1 - 0.23 11.9 0.0 1.5 9.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) bZIP_1 PF00170.21 KXZ54492.1 - 0.027 14.6 7.7 0.046 13.8 7.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 KXZ54492.1 - 0.13 12.9 0.1 0.22 12.2 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 KXZ54492.1 - 0.24 11.5 12.5 0.35 11.0 1.9 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DUF4543 PF15076.6 KXZ54492.1 - 2.4 8.4 3.9 5.9 7.1 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Atg14 PF10186.9 KXZ54492.1 - 2.8 6.9 4.6 4.1 6.4 4.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5011 PF16403.5 KXZ54494.1 - 5.6e-14 52.0 19.6 1.8e-06 27.9 0.1 6.6 8 0 0 8 8 8 4 Domain of unknown function (DUF5011) PKD_channel PF08016.12 KXZ54494.1 - 8.7e-06 24.7 3.8 0.0031 16.3 2.7 2.4 2 0 0 2 2 2 2 Polycystin cation channel DUF72 PF01904.18 KXZ54494.1 - 0.023 14.8 0.8 0.055 13.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF72 Lectin_C PF00059.21 KXZ54495.1 - 8.6e-41 139.0 0.0 4.3e-14 53.2 0.0 6.1 6 0 0 6 6 6 4 Lectin C-type domain Xlink PF00193.17 KXZ54495.1 - 0.12 12.7 0.2 24 5.4 0.0 3.6 4 0 0 4 4 4 0 Extracellular link domain Adaptin_N PF01602.20 KXZ54496.1 - 1.4e-84 284.6 0.0 1.8e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXZ54496.1 - 1.3e-09 38.3 0.1 1.2e-07 32.0 0.0 3.2 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXZ54496.1 - 9.6e-08 31.7 3.6 0.98 9.9 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KXZ54496.1 - 4.9e-07 30.0 8.9 0.0085 16.5 0.1 6.6 3 2 6 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 KXZ54496.1 - 3.2 8.4 21.2 2.2 8.9 0.1 6.1 7 1 0 7 7 7 0 HEAT-like repeat Ribosomal_L44 PF00935.19 KXZ54499.1 - 1.6e-34 118.2 13.3 1.6e-34 118.2 13.3 1.3 1 1 0 1 1 1 1 Ribosomal protein L44 Rpr2 PF04032.16 KXZ54499.1 - 0.15 12.4 8.9 0.079 13.3 5.7 1.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Vanabin-2 PF11437.8 KXZ54499.1 - 0.25 11.5 11.0 0.5 10.6 5.1 2.1 1 1 0 2 2 2 0 Vanadium-binding protein 2 NOB1_Zn_bind PF08772.11 KXZ54499.1 - 4 7.7 13.2 0.058 13.6 1.7 2.2 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-PARP PF00645.18 KXZ54499.1 - 4.7 8.2 10.4 3.7 8.5 0.7 2.2 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Adaptin_N PF01602.20 KXZ54500.1 - 2.6e-118 395.9 10.0 3.6e-118 395.4 10.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KXZ54500.1 - 9e-52 175.2 0.1 2.3e-51 173.9 0.1 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KXZ54500.1 - 3.3e-36 123.9 0.0 2.2e-35 121.2 0.0 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KXZ54500.1 - 5.2e-17 62.0 8.0 1.4e-08 35.0 0.0 5.2 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 KXZ54500.1 - 1.2e-13 51.4 8.1 6.7e-08 32.7 1.2 3.5 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXZ54500.1 - 8.1e-07 29.4 8.1 0.00054 20.4 2.7 5.1 6 0 0 6 6 5 1 HEAT-like repeat HEAT PF02985.22 KXZ54500.1 - 0.00011 22.1 9.8 2.6 8.5 0.1 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_PBS PF03130.16 KXZ54500.1 - 0.00021 21.7 4.7 0.073 13.8 1.3 4.5 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Arm PF00514.23 KXZ54500.1 - 0.13 12.3 2.2 2.4 8.4 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 KXZ54500.1 - 0.22 11.2 2.7 3 7.5 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) MoaC PF01967.21 KXZ54500.1 - 0.28 11.3 1.0 0.49 10.5 0.1 1.8 2 0 0 2 2 2 0 MoaC family UNC45-central PF11701.8 KXZ54500.1 - 0.33 10.9 3.1 1 9.3 0.2 3.0 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central RIX1 PF08167.12 KXZ54500.1 - 3.4 7.4 6.5 13 5.5 0.4 3.9 3 2 2 5 5 5 0 rRNA processing/ribosome biogenesis Ephrin_rec_like PF07699.13 KXZ54501.1 - 6.3e-41 137.9 132.9 1.4e-07 31.1 7.3 15.3 7 6 10 17 17 17 16 Putative ephrin-receptor like NCD3G PF07562.14 KXZ54501.1 - 2.8e-09 36.8 93.6 0.0034 17.3 0.9 13.3 7 7 7 15 15 15 11 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KXZ54501.1 - 1.3e-07 31.9 85.6 0.22 11.9 0.5 15.8 8 6 4 14 14 14 9 TNFR/NGFR cysteine-rich region VSP PF03302.13 KXZ54501.1 - 0.037 12.9 100.2 0.092 11.6 8.0 8.0 1 1 5 7 7 7 0 Giardia variant-specific surface protein Ndc1_Nup PF09531.10 KXZ54501.1 - 9.4 4.8 10.2 13 4.3 10.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CPBP PF02517.16 KXZ54502.1 - 4.7e-18 65.4 3.6 4.7e-18 65.4 3.6 1.7 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease DUF1230 PF06799.11 KXZ54502.1 - 0.043 13.9 0.1 0.09 12.9 0.1 1.6 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 Pkinase_Tyr PF07714.17 KXZ54503.1 - 9.6e-44 149.6 0.0 9.5e-36 123.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ54503.1 - 1.4e-37 129.5 0.0 3.5e-36 124.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain GAF_2 PF13185.6 KXZ54503.1 - 8.3e-06 26.1 0.0 0.004 17.4 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF PF01590.26 KXZ54503.1 - 0.00017 22.2 0.1 0.35 11.5 0.0 2.9 2 1 1 3 3 3 2 GAF domain GAF_3 PF13492.6 KXZ54503.1 - 0.006 16.9 0.0 6.6 7.1 0.0 2.7 2 0 0 2 2 2 2 GAF domain Autoind_bind PF03472.15 KXZ54503.1 - 0.09 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Autoinducer binding domain Kinase-like PF14531.6 KXZ54503.1 - 0.099 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXZ54503.1 - 0.11 11.9 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family rve PF00665.26 KXZ54504.1 - 3.1e-11 43.5 0.0 7.4e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PHD PF00628.29 KXZ54504.1 - 2.2e-10 40.2 2.8 2.2e-10 40.2 2.8 1.8 2 0 0 2 2 2 1 PHD-finger RVT_1 PF00078.27 KXZ54504.1 - 1.5e-09 37.7 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KXZ54504.1 - 7.6e-06 25.9 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KXZ54504.1 - 1.2e-05 25.4 1.1 5.3e-05 23.2 1.1 2.2 1 1 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KXZ54504.1 - 0.0065 16.7 0.2 0.016 15.4 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger C1_2 PF03107.16 KXZ54504.1 - 0.02 15.2 2.3 0.021 15.2 0.2 2.1 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 KXZ54504.1 - 5.7 7.4 6.3 21 5.5 6.3 2.1 1 0 0 1 1 1 0 Ring finger domain Metal_resist PF13801.6 KXZ54505.1 - 0.01 16.0 0.3 0.01 16.0 0.3 2.0 3 0 0 3 3 3 0 Heavy-metal resistance 2Fe-2S_thioredx PF01257.19 KXZ54505.1 - 0.027 14.3 1.7 0.057 13.3 1.7 1.5 1 1 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin GCP_C_terminal PF04130.13 KXZ54505.1 - 0.044 13.2 0.1 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal FWWh PF14922.6 KXZ54507.1 - 1.5e-16 60.7 0.0 2.3e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF2582 PF10771.9 KXZ54507.1 - 0.098 12.8 0.2 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) Metal_resist PF13801.6 KXZ54508.1 - 0.0037 17.5 0.7 0.0037 17.5 0.7 2.6 3 0 0 3 3 3 1 Heavy-metal resistance 2Fe-2S_thioredx PF01257.19 KXZ54508.1 - 0.0068 16.3 0.8 0.016 15.1 0.8 1.6 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin GCP_C_terminal PF04130.13 KXZ54508.1 - 0.041 13.4 0.2 0.057 12.9 0.2 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal TFIIB PF00382.19 KXZ54509.1 - 8.2e-21 73.8 1.0 8.8e-17 60.9 0.6 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat RB_B PF01857.20 KXZ54509.1 - 0.029 14.4 0.1 0.056 13.5 0.1 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 KXZ54509.1 - 0.1 12.3 0.2 0.46 10.2 0.2 2.0 1 1 0 1 1 1 0 Cyclin, N-terminal domain His_Phos_2 PF00328.22 KXZ54510.1 - 1.1e-08 34.9 0.0 3.8e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) bZIP_2 PF07716.15 KXZ54511.1 - 3.9e-10 39.7 5.1 6.5e-10 38.9 5.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXZ54511.1 - 2.2e-07 30.9 5.8 3.3e-07 30.3 5.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXZ54511.1 - 0.00023 21.6 3.0 0.00037 20.9 3.0 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1465 PF07323.12 KXZ54511.1 - 0.12 12.3 1.9 0.18 11.6 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF3611 PF12263.8 KXZ54512.1 - 2.8e-47 160.9 10.3 3.6e-47 160.6 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Chloroa_b-bind PF00504.21 KXZ54513.1 - 2.6e-42 145.1 0.2 3.7e-42 144.6 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Sin_N PF04801.13 KXZ54514.1 - 3.8e-35 121.9 0.1 6.2e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region LRR_4 PF12799.7 KXZ54514.1 - 4.7e-28 96.8 14.5 2.9e-08 33.9 0.7 5.7 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ54514.1 - 2.1e-18 65.8 24.3 8.5e-09 35.0 3.9 5.8 2 1 5 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 KXZ54514.1 - 8.6e-09 35.1 0.2 0.034 13.7 0.0 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KXZ54514.1 - 3.5e-08 32.9 14.0 1.1 9.5 0.1 6.8 5 1 1 6 6 6 5 Leucine Rich repeat LRR_1 PF00560.33 KXZ54514.1 - 0.0011 19.3 12.8 14 6.7 0.1 6.9 7 0 0 7 7 7 1 Leucine Rich Repeat SOUL PF04832.12 KXZ54515.1 - 2.4e-34 118.9 0.0 3.8e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 SOUL heme-binding protein Invas_SpaK PF03519.14 KXZ54515.1 - 0.034 14.2 0.1 0.098 12.7 0.0 1.8 2 0 0 2 2 2 0 Invasion protein B family RSRP PF17069.5 KXZ54515.1 - 0.085 12.4 6.6 0.12 11.9 6.6 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CmcI PF04989.12 KXZ54516.1 - 5.5e-129 427.9 0.0 1.9e-41 142.0 0.0 3.3 3 0 0 3 3 3 3 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 KXZ54516.1 - 1e-22 81.1 0.9 1.2e-05 26.3 0.0 4.1 4 0 0 4 4 4 3 Methyltransferase domain NRDE-2 PF08424.10 KXZ54516.1 - 0.0002 20.6 0.0 2.3 7.3 0.0 3.7 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference NOG1 PF06858.14 KXZ54516.1 - 0.00033 20.4 0.1 6.9 6.5 0.0 3.6 3 0 0 3 3 3 2 Nucleolar GTP-binding protein 1 (NOG1) bMG10 PF17973.1 KXZ54516.1 - 0.037 14.2 2.8 41 4.4 0.1 3.5 3 0 0 3 3 3 0 Bacterial Alpha-2-macroglobulin MG10 domain Trns_repr_metal PF02583.17 KXZ54516.1 - 0.079 13.3 0.7 32 5.0 0.1 3.3 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor UBA_5 PF16577.5 KXZ54516.1 - 0.15 12.2 0.0 1.6e+02 2.5 0.0 3.5 3 0 0 3 3 3 0 UBA domain Activator_LAG-3 PF11498.8 KXZ54516.1 - 0.2 10.6 0.5 28 3.5 0.0 2.8 3 0 0 3 3 3 0 Transcriptional activator LAG-3 Sulfotransfer_3 PF13469.6 KXZ54517.1 - 6.2e-16 59.4 0.2 1.3e-07 32.2 0.2 3.0 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KXZ54517.1 - 5.5e-13 49.0 0.0 5.4e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KXZ54517.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase domain DUF4054 PF13262.6 KXZ54517.1 - 2.7 8.1 4.4 42 4.2 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) LSM PF01423.22 KXZ54518.1 - 1.4e-13 50.3 0.1 2.2e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 LSM domain DUF155 PF02582.14 KXZ54519.1 - 0.00075 19.6 0.0 0.0089 16.1 0.0 2.1 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Vezatin PF12632.7 KXZ54519.1 - 0.06 12.7 0.1 0.092 12.1 0.1 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes FKBP_C PF00254.28 KXZ54520.1 - 3e-17 62.7 0.0 4.1e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase tRNA_m1G_MT PF01746.21 KXZ54521.1 - 1.6e-11 44.3 0.0 6e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase 5_nucleotid PF05761.14 KXZ54522.1 - 1.4e-160 535.2 0.0 1.8e-160 534.8 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family Pro_isomerase PF00160.21 KXZ54522.1 - 2.1e-35 122.3 0.0 9.3e-35 120.2 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 KXZ54522.1 - 1.9e-06 27.4 0.1 6.3e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KXZ54522.1 - 9.5e-05 22.5 0.1 0.00029 20.9 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 KXZ54522.1 - 0.0035 17.5 0.1 0.01 16.0 0.1 1.7 1 0 0 1 1 1 1 U-box domain DNA_pol_B_2 PF03175.13 KXZ54522.1 - 0.22 10.4 0.0 0.33 9.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Methyltransf_11 PF08241.12 KXZ54523.1 - 2.4e-14 53.7 0.0 3.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ54523.1 - 3e-12 47.1 0.1 5.8e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ54523.1 - 7.2e-07 29.1 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KXZ54523.1 - 4e-06 26.7 0.0 1.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 KXZ54523.1 - 8.4e-06 26.5 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ54523.1 - 0.00012 21.9 0.0 0.00038 20.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KXZ54523.1 - 0.00052 19.7 0.0 0.00073 19.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KXZ54523.1 - 0.0041 16.5 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Se-cys_synth_N PF12390.8 KXZ54523.1 - 0.37 11.1 4.2 2.3 8.5 0.0 3.1 3 0 0 3 3 3 0 Selenocysteine synthase N terminal C2 PF00168.30 KXZ54524.1 - 9.4e-19 67.6 0.1 1.6e-18 66.9 0.0 1.4 2 0 0 2 2 2 1 C2 domain TnpB_IS66 PF05717.13 KXZ54524.1 - 0.055 13.4 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 IS66 Orf2 like protein 2OG-FeII_Oxy_4 PF13661.6 KXZ54524.1 - 0.06 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-RING_5 PF14634.6 KXZ54525.1 - 2.6e-08 33.7 2.2 4.5e-08 32.9 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXZ54525.1 - 5.7e-07 29.8 1.6 1.1e-06 28.9 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ54525.1 - 3.2e-06 26.9 2.6 6.4e-06 25.9 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXZ54525.1 - 3.4e-05 23.5 0.8 7.5e-05 22.4 0.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KXZ54525.1 - 4.8e-05 23.6 4.1 8.6e-05 22.8 4.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXZ54525.1 - 0.0058 16.6 2.3 0.014 15.4 2.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXZ54525.1 - 0.051 13.5 2.7 0.12 12.3 2.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXZ54525.1 - 1.6 8.8 6.8 0.81 9.8 4.4 1.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Isochorismatase PF00857.20 KXZ54526.1 - 3.7e-25 89.1 0.4 5.4e-25 88.6 0.1 1.4 1 1 1 2 2 2 1 Isochorismatase family DUF4328 PF14219.6 KXZ54530.1 - 0.032 13.8 1.2 0.057 13.0 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) BatA PF07584.11 KXZ54530.1 - 0.034 14.5 0.4 0.034 14.5 0.4 2.3 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF4381 PF14316.6 KXZ54530.1 - 1.6 9.0 8.3 0.11 12.8 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Glyoxal_oxid_N PF07250.11 KXZ54532.1 - 1.1e-22 80.5 0.0 9.4e-20 70.8 0.0 3.1 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KXZ54532.1 - 6.7e-19 68.0 0.0 2.3e-18 66.2 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KXZ54532.1 - 5.5e-05 23.3 10.5 0.075 13.4 0.0 5.6 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KXZ54532.1 - 0.0053 16.7 12.3 2.1 8.5 0.1 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KXZ54532.1 - 0.038 14.0 1.7 13 6.0 0.0 4.3 4 0 0 4 4 4 0 Kelch motif SpuA_C PF18033.1 KXZ54534.1 - 0.027 14.5 0.7 0.047 13.7 0.4 1.5 1 1 0 1 1 1 0 SpuA C-terminal DUF5521 PF17659.1 KXZ54534.1 - 7.9 4.2 7.7 8.7 4.1 7.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF262 PF03235.14 KXZ54535.1 - 2.6e-28 99.7 0.0 4.7e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 Anth_synt_I_N PF04715.13 KXZ54537.1 - 1.3e-25 90.3 0.0 2.1e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Chorismate_bind PF00425.18 KXZ54537.1 - 6.1e-18 65.3 0.6 1e-10 41.6 0.0 2.7 2 1 1 3 3 3 2 chorismate binding enzyme Phage_fiber_2 PF03406.13 KXZ54537.1 - 0.27 10.8 1.3 0.44 10.1 0.2 1.9 2 0 0 2 2 2 0 Phage tail fibre repeat Ribonuclease_T2 PF00445.18 KXZ54538.1 - 7.4e-50 169.7 0.4 1e-49 169.2 0.4 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Aminotran_1_2 PF00155.21 KXZ54539.1 - 9.6e-38 130.3 0.0 2.9e-23 82.7 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Fer2 PF00111.27 KXZ54540.1 - 1e-16 60.7 1.3 1.6e-16 60.0 1.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 KXZ54540.1 - 0.25 11.4 2.8 0.43 10.7 0.0 2.5 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain AAA_lid_2 PF17863.1 KXZ54541.1 - 1.1e-22 79.7 0.2 2.4e-22 78.5 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 KXZ54541.1 - 2.3e-12 46.7 0.2 1.6e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 KXZ54541.1 - 3.2e-07 29.7 0.0 0.00048 19.3 0.0 2.5 2 1 0 2 2 2 2 MCM P-loop domain AAA_5 PF07728.14 KXZ54541.1 - 2.9e-06 27.3 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ54541.1 - 7.3e-05 23.1 0.0 0.00027 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ54541.1 - 0.0001 22.7 0.0 0.0006 20.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 KXZ54541.1 - 0.00032 20.4 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KXZ54541.1 - 0.00094 19.7 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KXZ54541.1 - 0.0023 18.4 0.0 0.032 14.7 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KXZ54541.1 - 0.0035 17.1 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 KXZ54541.1 - 0.0066 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 KXZ54541.1 - 0.017 14.9 2.1 0.54 9.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KXZ54541.1 - 0.027 15.0 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXZ54541.1 - 0.028 13.6 0.2 2.6 7.1 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 KXZ54541.1 - 0.038 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXZ54541.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KXZ54542.1 - 1.7e-33 115.8 0.1 6.5e-33 113.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ54542.1 - 9.1e-27 93.6 0.2 8.5e-26 90.5 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ54542.1 - 5.9e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 KXZ54542.1 - 0.33 10.8 1.2 1.8 8.4 0.7 2.4 1 1 1 2 2 2 0 NACHT domain Kdo PF06293.14 KXZ54543.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_1 PF00036.32 KXZ54544.1 - 1.6e-08 33.5 1.0 0.0019 17.6 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXZ54544.1 - 2e-08 33.5 0.2 0.0061 16.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KXZ54544.1 - 9.7e-07 29.2 0.6 3.8e-06 27.3 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ54544.1 - 1.4e-05 24.8 0.1 3.1e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ54544.1 - 0.0019 17.6 0.4 0.33 10.5 0.1 2.4 2 0 0 2 2 2 2 EF hand NOA36 PF06524.12 KXZ54544.1 - 0.014 14.7 3.1 0.019 14.3 3.1 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KXZ54544.1 - 2.3 6.2 4.8 2.6 6.1 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi EF-hand_6 PF13405.6 KXZ54545.1 - 0.016 15.1 0.2 4.5 7.5 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KXZ54545.1 - 0.046 14.2 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_M48 PF01435.18 KXZ54546.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M14 PF00246.24 KXZ54547.1 - 8.9e-31 107.8 0.0 1.2e-30 107.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.8 KXZ54547.1 - 9.8e-05 21.9 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 KXZ54547.1 - 0.0043 16.2 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family FAST_1 PF06743.15 KXZ54548.1 - 8.1e-12 44.9 0.0 0.00081 19.3 0.0 5.6 6 0 0 6 6 6 3 FAST kinase-like protein, subdomain 1 ER_lumen_recept PF00810.18 KXZ54549.1 - 4e-33 115.3 9.3 5.6e-33 114.8 9.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXZ54549.1 - 0.0057 16.4 2.5 0.19 11.5 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF4079 PF13301.6 KXZ54549.1 - 0.45 10.7 2.4 0.47 10.6 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) RrnaAD PF00398.20 KXZ54550.1 - 1.6e-33 115.9 0.0 1.1e-17 64.0 0.0 2.0 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 KXZ54550.1 - 9.5e-05 23.0 0.0 0.00023 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ54550.1 - 0.00023 21.8 0.0 0.00061 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ54550.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ54550.1 - 0.12 13.1 0.3 0.88 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain ABC_membrane PF00664.23 KXZ54551.1 - 1.7e-44 152.5 31.1 4e-23 82.4 14.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ54551.1 - 6.3e-37 127.1 0.0 1.1e-25 90.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXZ54551.1 - 2.1e-07 30.6 0.3 0.005 16.3 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ54551.1 - 4.1e-06 26.4 0.0 0.041 13.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXZ54551.1 - 6e-05 23.1 1.5 0.016 15.3 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KXZ54551.1 - 0.00045 20.1 0.4 0.48 10.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KXZ54551.1 - 0.0047 17.0 1.6 0.033 14.3 0.5 2.2 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KXZ54551.1 - 0.0078 16.1 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXZ54551.1 - 0.0081 16.5 0.1 0.23 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KXZ54551.1 - 0.0088 15.4 0.1 4.1 6.7 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.6 KXZ54551.1 - 0.011 15.4 0.1 4 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXZ54551.1 - 0.016 15.5 0.5 9.8 6.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXZ54551.1 - 0.026 15.0 0.0 2.6 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXZ54551.1 - 0.12 12.5 2.8 2.6 8.1 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 KXZ54551.1 - 0.22 11.2 0.0 14 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KXZ54551.1 - 0.24 10.9 0.1 9.8 5.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MNSV_P7B PF06692.11 KXZ54551.1 - 0.76 9.8 2.5 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein cobW PF02492.19 KXZ54551.1 - 0.82 9.2 2.3 1 8.9 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXZ54551.1 - 0.9 9.4 3.7 1.3 8.9 0.5 2.5 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 KXZ54551.1 - 6 6.1 5.3 13 5.0 0.2 2.7 3 0 0 3 3 3 0 AIG1 family Zeta_toxin PF06414.12 KXZ54551.1 - 9.7 5.4 6.9 4.3 6.6 0.1 3.0 4 0 0 4 4 3 0 Zeta toxin Form_Nir_trans PF01226.17 KXZ54552.1 - 1.6e-69 233.9 26.3 1.8e-69 233.7 26.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter NOT2_3_5 PF04153.18 KXZ54553.1 - 1.7e-26 92.8 0.2 1.7e-26 92.8 0.2 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Pex14_N PF04695.13 KXZ54553.1 - 0.014 16.0 9.7 0.045 14.4 9.7 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 KXZ54553.1 - 0.04 14.1 0.8 0.058 13.5 0.8 1.2 1 0 0 1 1 1 0 DDHD domain EBP50_C PF09007.11 KXZ54553.1 - 0.16 12.9 5.3 0.29 12.1 5.3 1.3 1 0 0 1 1 1 0 EBP50, C-terminal Tim54 PF11711.8 KXZ54553.1 - 0.2 10.4 4.4 0.33 9.7 4.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 KXZ54553.1 - 0.21 11.6 0.8 0.28 11.2 0.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 KXZ54553.1 - 0.24 11.2 4.5 0.34 10.7 4.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 KXZ54553.1 - 1.1 7.3 5.9 1.4 6.9 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4746 PF15928.5 KXZ54553.1 - 1.1 8.7 4.3 1.6 8.1 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 KXZ54553.1 - 1.9 8.4 32.3 0.018 15.1 24.5 1.5 2 0 0 2 2 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 KXZ54553.1 - 2.4 8.6 11.7 5.4 7.4 11.7 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4366 PF14283.6 KXZ54553.1 - 4.1 7.4 6.2 11 6.1 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) EPL1 PF10513.9 KXZ54553.1 - 4.7 7.6 8.1 8.1 6.8 8.1 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Ndc1_Nup PF09531.10 KXZ54553.1 - 6.7 5.3 6.3 9.3 4.8 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KXZ54553.1 - 9.4 4.9 11.3 13 4.4 11.3 1.1 1 0 0 1 1 1 0 Presenilin Cpn60_TCP1 PF00118.24 KXZ54554.1 - 4.6e-47 160.8 11.2 2.2e-46 158.5 11.2 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family MGAT2 PF05060.14 KXZ54554.1 - 0.077 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Cpn60_TCP1 PF00118.24 KXZ54556.1 - 1.4e-28 99.9 6.4 3.8e-28 98.4 6.4 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family OCRE PF17780.1 KXZ54557.1 - 2.2e-06 27.6 5.6 3.7e-06 26.9 5.6 1.3 1 0 0 1 1 1 1 OCRE domain zf-U1 PF06220.12 KXZ54557.1 - 8.1e-05 22.3 0.7 0.00015 21.5 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 KXZ54557.1 - 5.2 7.5 6.2 4.1 7.8 4.1 2.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rhodanese PF00581.20 KXZ54559.1 - 5.4e-11 43.0 0.0 8.1e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Mito_carr PF00153.27 KXZ54560.1 - 8.3e-31 105.8 1.2 1.8e-11 43.8 0.0 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein CCCAP PF15964.5 KXZ54561.1 - 1.5e-06 26.8 11.0 1.5e-06 26.8 11.0 5.7 3 2 3 6 6 6 4 Centrosomal colon cancer autoantigen protein family GAS PF13851.6 KXZ54561.1 - 0.00059 19.2 2.5 0.00059 19.2 2.5 7.2 4 1 5 9 9 9 5 Growth-arrest specific micro-tubule binding HOOK PF05622.12 KXZ54561.1 - 0.0017 16.6 26.0 0.0017 16.6 26.0 5.1 3 1 3 6 6 6 3 HOOK protein TACC_C PF05010.14 KXZ54561.1 - 0.005 16.7 3.8 0.005 16.7 3.8 7.7 3 1 4 8 8 8 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-H PF05837.12 KXZ54561.1 - 0.012 16.0 3.8 0.012 16.0 3.8 10.0 4 1 6 11 11 11 0 Centromere protein H (CENP-H) YabA PF06156.13 KXZ54561.1 - 0.021 15.5 0.7 0.021 15.5 0.7 9.5 3 1 6 10 10 10 0 Initiation control protein YabA TcdB_N PF12918.7 KXZ54561.1 - 0.11 12.9 0.2 9.9 6.5 0.0 3.3 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain UPF0184 PF03670.13 KXZ54561.1 - 5.8 7.4 17.9 5.6 7.4 0.2 5.3 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) Endosulfine PF04667.17 KXZ54562.1 - 8.9e-14 51.4 1.8 1.1e-13 51.1 1.8 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Glyco_hydro_14 PF01373.17 KXZ54563.1 - 2.4e-116 389.0 0.0 5.1e-114 381.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 14 ABC1 PF03109.16 KXZ54564.1 - 1.4e-15 57.5 0.1 6.9e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.22 KXZ54564.1 - 0.018 14.6 0.0 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family LysM PF01476.20 KXZ54564.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 LysM domain Pkinase PF00069.25 KXZ54564.1 - 0.22 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 KXZ54565.1 - 5.7e-67 225.8 0.0 7.4e-43 146.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54565.1 - 8.9e-29 100.6 0.0 1.8e-22 79.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ54565.1 - 0.00018 20.9 0.1 0.01 15.2 0.1 2.7 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 KXZ54565.1 - 0.00029 20.9 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ54565.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KXZ54565.1 - 0.025 14.2 0.1 0.051 13.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KXZ54565.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRCR PF00530.18 KXZ54567.1 - 3.2e-20 72.5 0.1 7.4e-11 42.4 0.1 4.3 3 1 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ54567.1 - 3.8e-07 30.5 0.1 0.00051 20.5 0.0 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain ArfGap PF01412.18 KXZ54568.1 - 1.4e-34 118.7 0.0 2.2e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ENTH PF01417.20 KXZ54568.1 - 9.7e-17 61.2 0.0 1.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 ENTH domain TT_ORF2 PF02957.15 KXZ54568.1 - 0.052 14.5 3.8 0.23 12.4 0.7 2.5 2 0 0 2 2 2 0 TT viral ORF2 Pkinase PF00069.25 KXZ54569.1 - 2.5e-19 69.7 0.0 3.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Exo_endo_phos PF03372.23 KXZ54569.1 - 1.4e-08 34.6 0.2 2.2e-08 33.9 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase_Tyr PF07714.17 KXZ54569.1 - 8.9e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Exo_endo_phos PF03372.23 KXZ54570.1 - 3.6e-10 39.8 0.2 5.9e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PRP21_like_P PF12230.8 KXZ54571.1 - 8.4e-53 179.5 5.4 1.5e-52 178.7 5.4 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KXZ54571.1 - 5.7e-41 138.3 3.2 1.3e-19 69.9 0.6 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 KXZ54571.1 - 2.3e-05 24.0 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Toprim_Crpt PF13342.6 KXZ54571.1 - 0.13 12.3 1.9 9.6 6.3 0.0 2.4 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase LCIB_C_CA PF18599.1 KXZ54572.1 - 1.5e-78 263.2 0.0 2e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases NAP PF00956.18 KXZ54574.1 - 1.4e-21 76.9 3.0 8.1e-15 54.7 0.2 3.0 2 1 1 3 3 3 3 Nucleosome assembly protein (NAP) SecA_SW PF07516.13 KXZ54574.1 - 0.042 13.9 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Glyco_hydro_9 PF00759.19 KXZ54577.1 - 1.4e-60 205.9 12.3 1.7e-60 205.6 12.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 RT_RNaseH_2 PF17919.1 KXZ54578.1 - 9.3e-34 115.5 0.0 2.2e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ54578.1 - 4.5e-31 107.2 0.8 1.1e-30 106.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KXZ54578.1 - 8e-16 58.3 0.0 2.1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KXZ54578.1 - 6.8e-14 51.7 1.6 2.6e-13 49.8 1.6 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain PHD PF00628.29 KXZ54578.1 - 2.2e-05 24.3 6.9 2.2e-05 24.3 6.9 2.4 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 KXZ54578.1 - 0.0016 18.6 0.7 0.004 17.4 0.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.8 KXZ54578.1 - 0.029 14.5 1.2 0.075 13.2 1.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-H2C2 PF09337.10 KXZ54578.1 - 0.17 12.1 4.3 0.061 13.5 1.4 1.9 2 0 0 2 2 2 0 H2C2 zinc finger DUF2880 PF11082.8 KXZ54579.1 - 0.089 13.1 1.5 17 5.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) Speriolin_N PF15058.6 KXZ54579.1 - 0.26 11.3 13.5 0.85 9.7 0.3 3.0 3 0 0 3 3 3 0 Speriolin N terminus DUF5476 PF17570.2 KXZ54579.1 - 0.77 10.2 6.5 4.6 7.7 1.2 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5476) ACC_epsilon PF13822.6 KXZ54579.1 - 1.5 9.5 6.7 13 6.5 0.2 2.7 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit Peptidase_M11 PF05548.11 KXZ54580.1 - 3.8e-22 78.8 0.0 3.2e-12 46.2 0.1 3.0 2 1 0 2 2 2 2 Gametolysin peptidase M11 Reprolysin_5 PF13688.6 KXZ54580.1 - 0.11 12.6 0.2 0.33 11.1 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 RabGAP-TBC PF00566.18 KXZ54581.1 - 4.2e-43 147.5 9.6 1.1e-26 93.8 0.3 2.8 3 1 0 3 3 3 2 Rab-GTPase-TBC domain DUF2722 PF10846.8 KXZ54581.1 - 3.8e-05 22.8 6.6 0.00038 19.5 2.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DDHD PF02862.17 KXZ54581.1 - 0.01 16.0 2.6 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 DDHD domain DUF1925 PF09094.11 KXZ54581.1 - 0.11 12.8 0.8 0.32 11.3 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) CCDC53 PF10152.9 KXZ54581.1 - 0.12 12.7 0.0 0.12 12.7 0.0 5.4 4 1 0 4 4 4 0 Subunit CCDC53 of WASH complex EIIBC-GUT_N PF03612.14 KXZ54581.1 - 0.52 10.0 7.2 2 8.1 2.8 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 KXZ54581.1 - 0.56 10.1 41.4 0.011 15.8 4.2 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF4230 PF14014.6 KXZ54581.1 - 0.84 9.9 8.8 2.1 8.6 8.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DUF4834 PF16118.5 KXZ54581.1 - 3.4 8.7 9.3 0.33 11.9 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3707 PF12499.8 KXZ54582.1 - 5.7e-21 75.6 21.4 2.2e-13 51.0 1.4 4.0 4 1 0 4 4 4 2 Pherophorin SKG6 PF08693.10 KXZ54582.1 - 0.014 14.8 5.3 0.028 13.8 5.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KXZ54582.1 - 0.073 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAG1 PF05454.11 KXZ54582.1 - 0.083 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) ERG4_ERG24 PF01222.17 KXZ54584.1 - 1.7e-33 116.1 0.1 2.1e-33 115.7 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family WD40 PF00400.32 KXZ54585.1 - 2.3e-15 56.7 0.1 0.00016 22.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ54585.1 - 1.3e-05 25.4 0.0 0.0023 18.2 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ54585.1 - 0.0018 17.3 0.0 0.14 11.1 0.0 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 KXZ54586.1 - 3.5e-65 220.0 0.0 5e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KXZ54586.1 - 4.4e-60 199.8 0.6 1.6e-18 66.5 0.0 5.0 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KXZ54586.1 - 1.6e-29 103.0 0.0 3e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ54586.1 - 3.5e-06 26.6 0.4 1.4e-05 24.6 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.24 KXZ54586.1 - 0.0045 17.7 0.4 0.012 16.3 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KXZ54586.1 - 0.022 14.7 0.0 1.5 8.7 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 KXZ54587.1 - 4.2e-37 128.6 0.0 5.4e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXZ54587.1 - 0.028 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 KXZ54587.1 - 0.034 14.6 0.1 0.072 13.5 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF4368 PF14287.6 KXZ54587.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) Y_phosphatase3 PF13350.6 KXZ54589.1 - 7.1e-05 22.9 0.1 0.00012 22.1 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KXZ54589.1 - 0.00014 22.0 0.0 0.0002 21.5 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KXZ54589.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTEN_C2 PF10409.9 KXZ54589.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 KXZ54589.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Raf1_N PF18578.1 KXZ54590.1 - 7.8e-27 93.8 0.0 1.3e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Rubisco accumulation factor 1 alpha helical domain Raf1_HTH PF18579.1 KXZ54590.1 - 8.5e-22 76.6 0.0 1.7e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain RuBisCo_chap_C PF18087.1 KXZ54590.1 - 3.4e-12 46.2 0.1 1.6e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Rubisco Assembly chaperone C-terminal domain CPSase_sm_chain PF00988.22 KXZ54591.1 - 2.6e-47 159.8 0.0 4.3e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KXZ54591.1 - 8.3e-46 156.2 0.1 2.8e-45 154.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXZ54591.1 - 4e-06 26.7 0.4 0.00026 20.8 0.4 2.3 1 1 0 1 1 1 1 Peptidase C26 DUF5323 PF17257.2 KXZ54592.1 - 1.1e-12 47.6 3.1 1.2e-12 47.4 3.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5323) MBOAT_2 PF13813.6 KXZ54595.1 - 1.2e-08 35.0 0.3 0.00021 21.5 0.1 2.5 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family MBOAT PF03062.19 KXZ54595.1 - 0.0017 17.8 2.7 0.0087 15.4 2.7 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family HlyIII PF03006.20 KXZ54596.1 - 0.0074 16.0 7.9 0.091 12.5 7.9 2.1 1 1 0 1 1 1 1 Haemolysin-III related Glyco_hydro_9 PF00759.19 KXZ54597.1 - 1.2e-70 239.0 3.3 1.2e-70 239.0 3.3 3.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 9 B_lectin PF01453.24 KXZ54597.1 - 2.1e-14 53.9 7.2 0.29 11.7 0.0 8.2 7 2 1 8 8 8 5 D-mannose binding lectin Cyt_bd_oxida_II PF02322.15 KXZ54597.1 - 0.0061 16.0 14.9 0.012 15.0 14.9 1.3 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Peptidase_M11 PF05548.11 KXZ54600.1 - 1.1e-24 87.1 0.0 8e-13 48.2 0.0 2.0 2 0 0 2 2 2 2 Gametolysin peptidase M11 Cu-binding_MopE PF11617.8 KXZ54600.1 - 0.75 10.0 9.4 1.8 8.8 9.4 1.7 1 0 0 1 1 1 0 Putative metal-binding motif ABC2_membrane_3 PF12698.7 KXZ54601.1 - 7e-15 55.0 4.6 7e-15 55.0 4.6 1.4 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 KXZ54601.1 - 2.1e-13 50.9 0.0 6.7e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ54601.1 - 1.1e-09 38.5 0.1 4.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KXZ54601.1 - 0.05 12.9 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin S-methyl_trans PF02574.16 KXZ54603.1 - 3.7e-65 220.4 0.0 4.4e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase SNF2_N PF00176.23 KXZ54604.1 - 1.7e-56 191.4 0.0 8.4e-55 185.9 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KXZ54604.1 - 4.3e-08 32.9 7.4 7.7e-08 32.1 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ54604.1 - 6e-07 29.4 9.2 1.3e-06 28.4 9.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ54604.1 - 1e-06 28.5 10.4 1.8e-06 27.7 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ54604.1 - 1.1e-06 28.9 10.4 2.4e-06 27.8 10.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXZ54604.1 - 2.2e-06 27.4 10.3 3.7e-06 26.7 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ54604.1 - 2e-05 24.4 9.3 5.1e-05 23.2 9.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXZ54604.1 - 5.1e-05 23.1 8.3 0.0001 22.1 8.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXZ54604.1 - 0.002 18.2 8.5 0.0044 17.1 8.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXZ54604.1 - 0.0023 18.2 5.8 0.005 17.1 5.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 KXZ54604.1 - 0.024 15.0 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_4 PF14570.6 KXZ54604.1 - 0.057 13.2 7.4 0.11 12.3 7.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KXZ54604.1 - 0.082 12.7 2.2 0.18 11.6 2.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 KXZ54604.1 - 0.82 9.8 2.7 1.6 8.9 2.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PAP_assoc PF03828.19 KXZ54605.1 - 2.4e-17 62.9 0.0 4.5e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXZ54605.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain AAA_lid_10 PF17872.1 KXZ54606.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA lid domain PHD PF00628.29 KXZ54607.1 - 1.1e-10 41.2 5.5 1.9e-10 40.4 5.5 1.4 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 KXZ54607.1 - 4.8e-08 33.5 0.0 9.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KXZ54607.1 - 2.4e-06 27.6 0.0 4.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KXZ54607.1 - 8.7e-06 26.1 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 KXZ54607.1 - 2.1e-05 24.3 0.0 4.5e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 BAH domain AAA_16 PF13191.6 KXZ54607.1 - 0.0015 18.9 0.3 0.0015 18.9 0.3 3.0 2 1 0 2 2 2 1 AAA ATPase domain zf-HC5HC2H PF13771.6 KXZ54607.1 - 0.011 15.9 0.2 0.022 15.0 0.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF2075 PF09848.9 KXZ54607.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 KXZ54607.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein C1_1 PF00130.22 KXZ54607.1 - 0.4 10.6 3.3 0.85 9.6 3.3 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 KXZ54607.1 - 1 9.7 9.0 1.8 8.9 9.0 1.4 1 0 0 1 1 1 0 Ring finger domain PHC2_SAM_assoc PF16616.5 KXZ54607.1 - 1.8 9.4 8.0 3.9 8.3 8.0 1.6 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 BET PF17035.5 KXZ54609.1 - 1.1e-08 35.2 0.5 1.8e-08 34.4 0.5 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF4351 PF14261.6 KXZ54609.1 - 0.81 9.8 5.2 1.8 8.7 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4351) Bromodomain PF00439.25 KXZ54610.1 - 5.4e-20 71.3 0.0 1.8e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 KXZ54610.1 - 9.5e-09 35.3 0.2 1.9e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FANCI_S1-cap PF14674.6 KXZ54610.1 - 0.2 11.8 4.0 4.2 7.5 0.2 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap PYRIN PF02758.16 KXZ54610.1 - 0.63 10.2 3.0 5.4 7.2 0.9 2.6 2 1 1 3 3 3 0 PAAD/DAPIN/Pyrin domain Methyltransf_25 PF13649.6 KXZ54612.1 - 9.7e-08 32.6 0.9 0.0019 18.8 0.3 3.2 2 1 0 3 3 3 2 Methyltransferase domain MTS PF05175.14 KXZ54612.1 - 4.6e-07 29.5 1.7 0.028 14.0 0.0 3.4 2 1 1 3 3 3 3 Methyltransferase small domain PrmA PF06325.13 KXZ54612.1 - 6.5e-06 25.7 0.6 0.11 11.9 0.4 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXZ54612.1 - 0.00035 20.4 0.0 0.22 11.3 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ54612.1 - 0.0014 19.3 0.2 0.05 14.2 0.1 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ54612.1 - 0.0017 19.1 0.0 1.8 9.4 0.1 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_15 PF09445.10 KXZ54612.1 - 0.0081 15.7 0.0 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 KXZ54612.1 - 0.0083 15.8 0.1 2.9 7.5 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 KXZ54612.1 - 0.011 15.6 0.8 0.088 12.6 0.8 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXZ54612.1 - 0.13 12.3 0.1 21 5.1 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase domain PCMT PF01135.19 KXZ54612.1 - 0.14 11.9 0.1 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KXZ54612.1 - 0.14 13.2 1.1 0.55 11.3 0.4 2.3 1 1 0 1 1 1 0 Methyltransferase domain GST_N_3 PF13417.6 KXZ54613.1 - 1.2e-11 44.9 0.0 2.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXZ54613.1 - 8.7e-10 38.8 0.0 2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXZ54613.1 - 1.3e-06 28.9 0.0 2.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ54613.1 - 3.4e-06 27.0 0.0 6.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXZ54613.1 - 0.00015 21.9 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 KXZ54613.1 - 0.00061 20.5 0.0 0.0011 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 KXZ54613.1 - 0.0021 18.4 0.0 0.0043 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Btz PF09405.10 KXZ54615.1 - 1.4e-08 35.0 1.3 1.4e-08 35.0 1.3 1.9 1 1 1 2 2 2 1 CASC3/Barentsz eIF4AIII binding DAP10 PF07213.11 KXZ54616.1 - 0.5 10.3 4.5 0.24 11.4 0.2 2.7 2 0 0 2 2 2 0 DAP10 membrane protein Ndc1_Nup PF09531.10 KXZ54617.1 - 3.8 6.1 4.7 1.7 7.2 0.8 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup TIR_2 PF13676.6 KXZ54618.1 - 5.9e-11 43.0 0.2 1.9e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 KXZ54618.1 - 1.5e-05 24.9 0.1 2.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 TIR domain VEFS-Box PF09733.9 KXZ54619.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 VEFS-Box of polycomb protein CHCH PF06747.13 KXZ54620.1 - 9.7e-06 25.6 1.2 2.8e-05 24.1 1.1 1.8 1 1 1 2 2 2 1 CHCH domain Pet191_N PF10203.9 KXZ54620.1 - 0.016 15.5 1.4 0.038 14.3 1.4 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KXZ54620.1 - 0.098 12.7 0.1 0.098 12.7 0.1 2.2 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like PP2C PF00481.21 KXZ54621.1 - 3e-19 69.7 0.0 5.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C zf-UBP PF02148.19 KXZ54622.1 - 3.8e-19 68.8 6.5 3.8e-19 68.8 6.5 1.8 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 KXZ54622.1 - 2.7e-18 66.0 0.0 9.1e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 BRCA1-associated protein 2 zf-RING_2 PF13639.6 KXZ54622.1 - 1.8e-09 37.8 7.7 1.8e-09 37.8 7.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ54622.1 - 1e-06 28.5 7.5 1e-06 28.5 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ54622.1 - 3.1e-06 27.4 6.0 3.1e-06 27.4 6.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXZ54622.1 - 6.5e-06 26.0 5.6 6.5e-06 26.0 5.6 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ54622.1 - 5.1e-05 23.1 6.8 5.1e-05 23.1 6.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ54622.1 - 0.00015 21.7 4.1 0.00015 21.7 4.1 2.7 1 1 1 2 2 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXZ54622.1 - 0.00034 20.3 3.8 0.00034 20.3 3.8 2.2 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXZ54622.1 - 0.0018 18.1 17.4 0.0032 17.3 7.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXZ54622.1 - 0.0057 16.7 6.5 0.0057 16.7 6.5 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXZ54622.1 - 0.016 15.0 6.9 0.016 15.0 6.9 3.5 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 Lebercilin PF15619.6 KXZ54622.1 - 0.096 12.3 6.0 0.18 11.5 6.0 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF2968 PF11180.8 KXZ54622.1 - 0.2 11.3 14.5 0.75 9.4 14.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) zf-C3H2C3 PF17122.5 KXZ54622.1 - 0.26 11.4 6.2 0.72 9.9 6.2 1.9 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 KXZ54622.1 - 1 9.2 7.4 2.5 7.9 7.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain APG6_N PF17675.1 KXZ54622.1 - 6.7 7.2 14.9 11 6.5 14.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Pro_isomerase PF00160.21 KXZ54623.1 - 2.3e-52 177.5 0.0 4.3e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KXZ54623.1 - 2.2e-06 28.3 0.8 0.064 14.2 0.0 4.3 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ54623.1 - 0.0012 19.1 0.0 0.82 10.0 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.6 KXZ54625.1 - 0.13 12.6 2.6 0.34 11.2 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ54625.1 - 0.6 10.4 23.2 1.1 9.6 0.9 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ54625.1 - 2.5 9.2 48.2 0.3 12.0 0.8 9.0 5 2 4 9 9 9 0 Tetratricopeptide repeat Ribosomal_S24e PF01282.19 KXZ54626.1 - 3.4e-27 94.2 0.1 6.6e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e Thioredoxin PF00085.20 KXZ54626.1 - 2e-07 30.9 0.0 6e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KXZ54626.1 - 0.00019 21.7 0.9 1.3 9.4 0.1 3.2 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KXZ54626.1 - 0.026 15.0 0.0 0.095 13.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain DUF2956 PF11169.8 KXZ54626.1 - 0.029 14.6 0.3 0.046 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Redoxin PF08534.10 KXZ54626.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Redoxin Kinesin PF00225.23 KXZ54627.1 - 2.1e-81 273.4 0.7 4e-81 272.5 0.7 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ54627.1 - 8.9e-21 74.4 2.1 1.4e-20 73.8 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding DUF3490 PF11995.8 KXZ54627.1 - 5.1e-19 68.7 0.1 5.1e-19 68.7 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3490) AAA_16 PF13191.6 KXZ54627.1 - 0.00027 21.4 0.0 0.00027 21.4 0.0 4.0 4 1 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 KXZ54627.1 - 0.0015 18.8 1.1 0.0052 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXZ54627.1 - 0.0053 17.2 0.2 0.27 11.6 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXZ54627.1 - 0.014 15.4 0.1 0.089 12.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KXZ54627.1 - 0.014 14.9 0.2 0.037 13.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran_Xtn PF12848.7 KXZ54627.1 - 0.024 14.6 0.3 0.024 14.6 0.3 5.2 5 1 1 6 6 3 0 ABC transporter ATPase_2 PF01637.18 KXZ54627.1 - 0.042 13.7 0.0 0.042 13.7 0.0 1.8 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KXZ54627.1 - 0.05 13.7 0.1 0.05 13.7 0.1 3.9 4 1 0 4 4 4 0 Helicase HerA, central domain G-alpha PF00503.20 KXZ54627.1 - 0.053 12.7 3.0 0.66 9.1 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit RNA_helicase PF00910.22 KXZ54627.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KXZ54627.1 - 0.076 12.7 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KXZ54627.1 - 0.077 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Septin Fez1 PF06818.15 KXZ54627.1 - 0.63 10.5 44.6 0.61 10.5 7.7 3.8 3 1 0 3 3 3 0 Fez1 ABC_tran PF00005.27 KXZ54627.1 - 3.7 8.1 5.4 3 8.3 0.0 3.2 3 0 0 3 3 3 0 ABC transporter SDF PF00375.18 KXZ54628.1 - 7.9e-109 364.2 33.0 1.1e-108 363.7 33.0 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Pex14_N PF04695.13 KXZ54628.1 - 1e-11 45.7 6.1 1e-11 45.7 6.1 2.7 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5572 PF17733.1 KXZ54628.1 - 9.1e-06 25.4 0.3 1.9e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) TFIIA PF03153.13 KXZ54628.1 - 3.2 7.7 5.0 5 7.0 5.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Brix PF04427.18 KXZ54629.1 - 9e-28 97.7 0.0 1.2e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain BTB PF00651.31 KXZ54630.1 - 0.00057 20.1 0.0 0.0017 18.6 0.0 1.8 3 0 0 3 3 3 1 BTB/POZ domain DUF1035 PF06281.12 KXZ54630.1 - 0.11 12.6 0.7 0.34 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) BTB PF00651.31 KXZ54633.1 - 0.024 14.9 0.0 0.062 13.5 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain Peptidase_S41 PF03572.18 KXZ54634.1 - 2.9e-48 163.6 0.0 4.1e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 KXZ54634.1 - 1.9e-15 56.4 0.2 4.2e-15 55.3 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KXZ54634.1 - 6.9e-09 35.9 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ54634.1 - 2.4e-07 31.0 0.0 1.7e-06 28.2 0.0 2.2 2 1 0 2 2 2 1 PDZ domain Tricorn_C1 PF14684.6 KXZ54634.1 - 0.018 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain Tricorn_PDZ PF14685.6 KXZ54634.1 - 0.098 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain ABC2_membrane PF01061.24 KXZ54635.1 - 1.9e-28 99.3 13.5 1.9e-28 99.3 13.5 3.0 3 0 0 3 3 3 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KXZ54635.1 - 0.00032 19.9 14.0 0.00032 19.9 14.0 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein EF-hand_1 PF00036.32 KXZ54635.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KXZ54635.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KXZ54635.1 - 0.21 11.1 0.0 0.45 10.1 0.0 1.5 1 0 0 1 1 1 0 EF hand LSM PF01423.22 KXZ54636.1 - 1.6e-17 62.9 0.2 2.2e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain NUDIX_5 PF16705.5 KXZ54636.1 - 0.049 13.4 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT TPM_phosphatase PF04536.14 KXZ54637.1 - 1.5e-12 47.8 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 TPM domain zf-RING_UBOX PF13445.6 KXZ54637.1 - 4.3e-05 23.4 0.4 4.3e-05 23.4 0.4 1.9 2 0 0 2 2 2 1 RING-type zinc-finger MOLO1 PF17175.4 KXZ54637.1 - 7e-05 22.9 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 zf-RING_5 PF14634.6 KXZ54637.1 - 0.00026 20.9 1.4 0.0005 20.0 0.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ54637.1 - 0.00031 20.5 0.1 0.00031 20.5 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ54637.1 - 0.001 19.4 3.4 0.012 15.9 0.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ54637.1 - 0.0032 17.3 0.3 0.0032 17.3 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXZ54637.1 - 0.018 15.2 1.1 0.018 15.2 1.1 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXZ54637.1 - 0.028 14.3 1.2 0.055 13.3 0.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXZ54637.1 - 0.032 14.0 4.6 0.24 11.2 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXZ54637.1 - 0.051 13.4 0.3 0.051 13.4 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BT1 PF03092.16 KXZ54637.1 - 0.23 9.7 0.0 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 BT1 family FAM212 PF15342.6 KXZ54637.1 - 9.6 6.1 6.2 1.8 8.4 2.1 1.9 2 0 0 2 2 2 0 FAM212 family Nucleoporin_FG PF13634.6 KXZ54639.1 - 0.21 12.4 17.0 2.2 9.2 17.0 2.2 1 1 0 1 1 1 0 Nucleoporin FG repeat region Peptidase_S26 PF10502.9 KXZ54640.1 - 1.7e-14 53.8 0.0 4.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KXZ54640.1 - 2.9e-12 46.3 0.6 6.5e-12 45.2 0.6 1.6 1 0 0 1 1 1 1 Peptidase S24-like DUF1180 PF06679.12 KXZ54640.1 - 0.2 12.0 6.8 0.31 11.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SR-25 PF10500.9 KXZ54640.1 - 7.7 6.0 14.5 12 5.4 14.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 KXZ54641.1 - 0.0044 17.6 0.0 0.026 15.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ54641.1 - 0.0047 17.3 0.0 0.11 13.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KXZ54641.1 - 0.031 14.8 0.0 0.39 11.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Acetyltransf_16 PF05301.11 KXZ54642.1 - 1.1e-53 181.6 0.0 1.4e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 KXZ54642.1 - 0.00025 21.4 0.0 0.00046 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXZ54642.1 - 0.0081 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ54642.1 - 0.023 15.0 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SBP PF03110.14 KXZ54643.1 - 5.5e-32 109.9 9.0 7.6e-32 109.5 9.0 1.2 1 0 0 1 1 1 1 SBP domain DUF1180 PF06679.12 KXZ54643.1 - 3.1 8.2 4.3 1.1 9.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Chloroa_b-bind PF00504.21 KXZ54644.1 - 1.4e-40 139.5 0.2 1.7e-40 139.2 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CAP59_mtransfer PF11735.8 KXZ54645.1 - 7.7e-59 199.3 0.0 1.3e-58 198.5 0.0 1.4 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RRM_1 PF00076.22 KXZ54647.1 - 6.6e-24 83.5 4.5 1.4e-08 34.4 0.2 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXZ54647.1 - 4.9e-05 23.6 0.2 5.5 7.2 0.0 3.8 3 0 0 3 3 3 3 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KXZ54647.1 - 0.00063 19.7 0.1 0.1 12.7 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif SET_assoc PF11767.8 KXZ54647.1 - 0.018 14.7 0.5 4.3 7.0 0.0 3.6 4 1 0 4 4 4 0 Histone lysine methyltransferase SET associated Psb28 PF03912.14 KXZ54647.1 - 0.17 12.2 0.8 29 5.0 0.1 2.8 3 0 0 3 3 3 0 Psb28 protein DCP2 PF05026.13 KXZ54648.1 - 1.5e-08 34.8 0.1 1.6e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KXZ54649.1 - 1.1e-15 57.8 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain COPI_C PF06957.11 KXZ54650.1 - 6.2 5.5 6.8 6.4 5.4 6.8 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus LRR_8 PF13855.6 KXZ54651.1 - 1.1e-17 63.6 17.2 2.5e-07 30.3 2.1 7.1 5 3 2 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 KXZ54651.1 - 5.5e-12 45.7 20.7 0.00036 20.9 0.2 7.4 5 2 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ54651.1 - 5.7e-09 35.3 13.0 0.27 11.9 0.3 7.1 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_9 PF14580.6 KXZ54651.1 - 9.8e-06 25.2 0.8 0.00019 21.0 0.3 2.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KXZ54651.1 - 0.00014 21.6 11.7 0.16 12.1 0.1 7.0 7 0 0 7 7 7 1 Leucine Rich repeat DUF4571 PF15137.6 KXZ54651.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4571) UDPGP PF01704.18 KXZ54652.1 - 7.5e-29 100.6 0.0 1.9e-28 99.3 0.0 1.6 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KXZ54652.1 - 0.0089 16.4 0.6 0.046 14.1 0.1 2.2 2 0 0 2 2 2 1 MobA-like NTP transferase domain Myb_DNA-binding PF00249.31 KXZ54653.1 - 1.9e-32 111.2 0.2 5.6e-16 58.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ54653.1 - 5e-26 90.7 0.1 1.4e-16 60.5 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXZ54653.1 - 0.079 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like SLIDE PF09111.10 KXZ54653.1 - 0.1 12.6 0.0 8.6 6.4 0.0 2.2 1 1 1 2 2 2 0 SLIDE LRR_6 PF13516.6 KXZ54655.1 - 3.1e-05 23.7 0.1 0.052 13.6 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KXZ54655.1 - 0.12 13.0 0.0 2.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich Repeat Polyketide_cyc PF03364.20 KXZ54656.1 - 7e-22 78.0 0.7 8.8e-22 77.7 0.7 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KXZ54656.1 - 4.8e-06 26.9 0.1 6.6e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PHD PF00628.29 KXZ54657.1 - 0.0014 18.5 0.2 0.0014 18.5 0.2 1.8 2 0 0 2 2 2 1 PHD-finger Acetyltransf_10 PF13673.7 KXZ54657.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_2 PF13831.6 KXZ54657.1 - 0.029 13.9 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 PHD-finger Acetyltransf_1 PF00583.25 KXZ54657.1 - 0.05 13.8 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF35_N PF12172.8 KXZ54657.1 - 3.6 7.6 8.5 2.3 8.2 0.7 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Roughex PF06020.11 KXZ54658.1 - 0.085 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CENP-B_dimeris PF09026.10 KXZ54658.1 - 0.48 10.8 2.6 0.81 10.1 2.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SASA PF03629.18 KXZ54659.1 - 9.8e-30 103.9 0.0 2e-29 102.9 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Cellulase PF00150.18 KXZ54659.1 - 5.3e-13 49.0 0.0 8.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KXZ54659.1 - 0.091 12.1 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Beta-galactosidase Aminopep PF10023.9 KXZ54659.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative aminopeptidase SAP130_C PF16014.5 KXZ54659.1 - 5.8 5.9 18.5 0.28 10.2 12.6 1.8 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus WD40 PF00400.32 KXZ54660.1 - 1.4e-46 155.5 25.9 1.4e-05 25.7 0.1 10.9 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp13 PF08625.11 KXZ54660.1 - 5.4e-35 120.4 0.0 8.5e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KXZ54660.1 - 2.8e-10 40.3 0.0 1.1 9.6 0.0 6.9 5 3 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_25 PF13649.6 KXZ54660.1 - 7.7e-07 29.7 0.1 3.3e-06 27.7 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Nup160 PF11715.8 KXZ54660.1 - 3e-06 26.2 4.6 3.9 6.0 0.0 5.4 4 1 1 5 5 5 4 Nucleoporin Nup120/160 PrmA PF06325.13 KXZ54660.1 - 5.8e-05 22.6 0.7 0.00012 21.6 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXZ54660.1 - 0.00044 20.9 0.1 0.0018 18.9 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KXZ54660.1 - 0.0089 15.6 0.0 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cytochrom_D1 PF02239.16 KXZ54660.1 - 0.1 11.1 0.0 0.19 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Cons_hypoth95 PF03602.15 KXZ54660.1 - 0.24 11.0 0.1 0.57 9.8 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ge1_WD40 PF16529.5 KXZ54660.1 - 0.76 8.7 1.2 14 4.5 0.1 3.4 3 3 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Q_salvage PF10343.9 KXZ54661.1 - 2.5e-84 283.2 0.0 3.5e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 KXZ54661.1 - 9.3e-05 21.3 0.0 0.0088 14.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1688) V-ATPase_H_N PF03224.14 KXZ54662.1 - 0.0057 16.0 0.0 0.088 12.1 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 KXZ54662.1 - 0.007 16.4 12.6 11 6.3 0.0 6.6 6 1 2 8 8 8 1 Armadillo/beta-catenin-like repeat PE PF00934.20 KXZ54662.1 - 3 8.2 14.8 0.095 13.0 4.1 3.1 3 0 0 3 3 3 0 PE family HEAT_EZ PF13513.6 KXZ54662.1 - 4.2 8.0 10.8 9 6.9 1.1 4.6 3 1 1 4 4 4 0 HEAT-like repeat F-box-like PF12937.7 KXZ54663.1 - 1.3e-05 25.0 0.6 2.3e-05 24.2 0.6 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXZ54663.1 - 0.00014 21.6 0.1 0.0002 21.1 0.1 1.3 1 0 0 1 1 1 1 F-box domain DUF4787 PF16029.5 KXZ54663.1 - 0.049 13.7 1.0 0.049 13.7 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4787) EF-hand_7 PF13499.6 KXZ54664.1 - 4.7e-05 23.7 0.0 5.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ54664.1 - 0.0012 18.2 0.1 0.0035 16.8 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXZ54664.1 - 0.0062 16.4 0.0 0.062 13.3 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KXZ54664.1 - 0.03 14.2 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain pair 2-oxoacid_dh PF00198.23 KXZ54665.1 - 4.8e-78 261.8 0.1 6.1e-78 261.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXZ54665.1 - 1.7e-12 47.0 5.0 3.3e-12 46.0 5.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXZ54665.1 - 0.0039 17.0 8.4 0.018 14.9 0.6 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like cNMP_binding PF00027.29 KXZ54666.1 - 1.9e-13 50.3 2.5 0.0008 19.4 0.0 5.4 6 0 0 6 6 6 4 Cyclic nucleotide-binding domain PH_17 PF18012.1 KXZ54666.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 PH domain UQ_con PF00179.26 KXZ54667.1 - 2e-25 89.0 0.1 2.6e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KXZ54667.1 - 6.4e-11 41.9 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain cNMP_binding PF00027.29 KXZ54668.1 - 2.3e-14 53.2 3.9 3e-05 24.0 0.0 5.2 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain PH_17 PF18012.1 KXZ54668.1 - 4.5e-05 23.1 0.6 0.43 10.3 0.1 2.5 2 0 0 2 2 2 2 PH domain DUF4225 PF13988.6 KXZ54671.1 - 0.032 13.8 0.5 0.037 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DUF1180 PF06679.12 KXZ54672.1 - 0.35 11.3 2.9 0.52 10.7 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) p450 PF00067.22 KXZ54673.1 - 1.4e-71 241.6 0.0 2.6e-56 191.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KXZ54674.1 - 6.2e-69 232.9 0.0 1.7e-54 185.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KXZ54675.1 - 8.3e-74 249.0 0.0 1.2e-58 199.0 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 Lysine_decarbox PF03641.14 KXZ54676.1 - 1.1e-37 129.1 0.1 1.6e-37 128.6 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXZ54676.1 - 1.2e-12 47.7 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 SLOG cluster4 family Nucleotid_trans PF03407.16 KXZ54677.1 - 1e-31 110.6 0.0 1.5e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 KXZ54677.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Pex14_N PF04695.13 KXZ54677.1 - 0.98 10.1 9.9 1.7 9.3 9.1 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_22 PF13383.6 KXZ54678.1 - 9.8e-21 74.5 0.0 7.7e-16 58.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 KXZ54678.1 - 3.7e-08 33.6 0.0 0.007 16.4 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase FkbM domain Sina PF03145.16 KXZ54678.1 - 0.094 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Seven in absentia protein family PKD_channel PF08016.12 KXZ54680.1 - 2.7e-10 39.5 12.5 3.9e-10 39.0 12.5 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KXZ54680.1 - 3.3e-09 36.4 11.6 5.3e-09 35.7 11.6 1.3 1 0 0 1 1 1 1 Ion transport protein F5_F8_type_C PF00754.25 KXZ54683.1 - 3.6e-07 30.3 0.1 1.1e-06 28.8 0.1 1.8 1 0 0 1 1 1 1 F5/8 type C domain PAN_4 PF14295.6 KXZ54684.1 - 2.1e-10 40.3 0.6 0.00028 20.7 0.1 4.1 3 0 0 3 3 3 3 PAN domain F5_F8_type_C PF00754.25 KXZ54684.1 - 1.7e-07 31.4 0.1 4.1e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain PAN_4 PF14295.6 KXZ54685.1 - 1.2e-08 34.7 5.6 9.2e-06 25.5 0.6 2.9 2 2 1 3 3 3 2 PAN domain PAN_2 PF08276.11 KXZ54685.1 - 0.033 14.3 1.8 1.5 9.0 0.3 2.7 2 1 0 2 2 2 0 PAN-like domain SapA PF02199.15 KXZ54685.1 - 9.2 6.7 8.7 12 6.3 0.6 2.6 2 0 0 2 2 2 0 Saposin A-type domain CBFD_NFYB_HMF PF00808.23 KXZ54686.1 - 5e-11 42.7 0.1 1.1e-10 41.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ54686.1 - 1.4e-07 31.9 0.3 7.2e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KXZ54686.1 - 0.00044 20.2 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAFII28 PF04719.14 KXZ54686.1 - 0.029 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Sec1 PF00995.23 KXZ54686.1 - 0.042 13.1 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Sec1 family CENP-T_C PF15511.6 KXZ54686.1 - 0.046 13.8 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PAN_4 PF14295.6 KXZ54687.1 - 1.3e-12 47.4 19.3 0.0013 18.6 0.0 7.4 7 0 0 7 7 7 3 PAN domain DUF1899 PF08953.11 KXZ54687.1 - 0.0056 16.5 0.4 8 6.4 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1899) DUF1264 PF06884.11 KXZ54687.1 - 0.072 12.7 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1264) F5_F8_type_C PF00754.25 KXZ54688.1 - 4.8e-10 39.7 0.7 1e-09 38.5 0.2 1.8 2 0 0 2 2 2 1 F5/8 type C domain PAN_4 PF14295.6 KXZ54688.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 4.2 4 0 0 4 4 4 1 PAN domain EGF_CA PF07645.15 KXZ54689.1 - 0.071 13.3 0.8 0.12 12.6 0.8 1.3 1 0 0 1 1 1 0 Calcium-binding EGF domain Pkinase PF00069.25 KXZ54690.1 - 2.9e-51 174.4 0.0 1.5e-50 172.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54690.1 - 3e-27 95.6 0.0 4.1e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ54690.1 - 6.5e-06 26.2 0.2 0.031 14.2 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KXZ54690.1 - 0.0007 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KXZ54690.1 - 0.00097 18.0 0.0 0.0023 16.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXZ54690.1 - 0.0059 16.0 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXZ54690.1 - 0.0062 16.2 0.2 0.63 9.6 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KXZ54690.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Mad3_BUB1_I PF08311.12 KXZ54691.1 - 1.2e-12 47.8 0.1 1.4e-12 47.6 0.1 1.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 KXZ54691.1 - 0.02 15.5 2.0 9.3 7.1 0.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Suf PF05843.14 KXZ54691.1 - 0.03 14.3 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-met PF12874.7 KXZ54692.1 - 1.8e-05 24.9 1.7 2.9e-05 24.3 1.7 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXZ54692.1 - 8.2e-05 22.8 0.5 0.00013 22.1 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 KXZ54692.1 - 0.00089 19.3 1.5 0.00089 19.3 1.5 3.0 3 0 0 3 3 3 1 U4/U6.U5 small nuclear ribonucleoproteins K_channel_TID PF07941.11 KXZ54692.1 - 0.0032 17.9 3.9 0.0032 17.9 3.9 2.2 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain 4F5 PF04419.14 KXZ54692.1 - 4.6 8.2 14.3 11 6.9 2.4 2.7 2 0 0 2 2 2 0 4F5 protein family DUF4554 PF15091.6 KXZ54692.1 - 8.7 5.1 6.0 1.1 8.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) CS PF04969.16 KXZ54693.1 - 1e-06 29.7 0.3 1.5e-06 29.1 0.3 1.3 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 KXZ54693.1 - 0.43 11.2 18.1 0.66 10.6 18.1 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region DUF533 PF04391.12 KXZ54693.1 - 2.2 7.8 4.8 3.3 7.2 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) GrpE PF01025.19 KXZ54694.1 - 1.2e-45 155.2 0.5 1.9e-45 154.5 0.5 1.4 1 1 0 1 1 1 1 GrpE DUF4047 PF13256.6 KXZ54694.1 - 0.025 14.8 0.8 0.041 14.1 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Hom_end PF05204.14 KXZ54694.1 - 0.042 14.0 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Homing endonuclease zf-C4H2 PF10146.9 KXZ54694.1 - 0.042 14.2 2.0 3.5 7.9 0.6 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein DLP_helical PF18709.1 KXZ54694.1 - 0.066 12.4 2.0 0.089 12.0 2.0 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain MscS_porin PF12795.7 KXZ54694.1 - 0.081 12.5 13.8 0.11 12.1 13.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ADIP PF11559.8 KXZ54694.1 - 0.12 12.4 7.5 0.18 11.9 4.4 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KXZ54694.1 - 0.17 11.7 4.8 0.53 10.1 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KXZ54694.1 - 0.3 10.4 6.7 8.9 5.6 8.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CAP_N PF01213.19 KXZ54694.1 - 0.33 10.4 3.5 0.45 10.0 3.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2408 PF10303.9 KXZ54694.1 - 0.36 11.4 4.2 0.74 10.4 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1640 PF07798.11 KXZ54694.1 - 0.38 10.8 5.4 0.61 10.1 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) APG6_N PF17675.1 KXZ54694.1 - 0.65 10.5 11.3 0.19 12.2 7.0 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KXZ54694.1 - 1.2 9.3 10.3 2.3 8.4 2.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KXZ54694.1 - 3.6 6.4 9.3 0.65 8.8 4.4 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein SDA1 PF05285.12 KXZ54695.1 - 0.64 9.4 9.2 0.91 8.9 9.2 1.1 1 0 0 1 1 1 0 SDA1 XAP5 PF04921.14 KXZ54696.1 - 2.7e-80 269.8 10.3 4.2e-80 269.2 0.0 2.8 1 1 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KXZ54696.1 - 7.3 7.0 23.0 0.61 10.5 14.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Guanylate_kin PF00625.21 KXZ54697.1 - 8.6e-57 191.7 0.0 1.4e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase adh_short PF00106.25 KXZ54697.1 - 1e-40 139.3 0.3 7e-40 136.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ54697.1 - 1.5e-29 103.2 0.0 2.5e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ54697.1 - 2e-06 27.8 0.3 7.5e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 KR domain AAA_18 PF13238.6 KXZ54697.1 - 0.00073 20.1 0.0 0.0019 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ54697.1 - 0.0025 18.0 0.0 0.0097 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXZ54697.1 - 0.0032 17.4 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase NAD_binding_10 PF13460.6 KXZ54697.1 - 0.0036 17.2 0.1 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXZ54697.1 - 0.0044 16.5 0.0 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXZ54697.1 - 0.0058 16.6 0.1 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AAA_16 PF13191.6 KXZ54697.1 - 0.014 15.8 0.3 0.029 14.8 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KXZ54697.1 - 0.017 14.9 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KXZ54697.1 - 0.022 15.0 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Polysacc_synt_2 PF02719.15 KXZ54697.1 - 0.095 11.8 0.0 0.21 10.7 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 KXZ54697.1 - 0.098 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA_28 PF13521.6 KXZ54697.1 - 0.11 12.7 0.4 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXZ54697.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 KXZ54697.1 - 0.13 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KXZ54697.1 - 0.15 12.0 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KXZ54697.1 - 0.19 12.2 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Exostosin PF03016.15 KXZ54698.1 - 1.3e-39 136.3 0.1 1.5e-38 132.7 0.1 2.0 1 1 0 1 1 1 1 Exostosin family B277 PF17623.2 KXZ54702.1 - 0.33 10.0 0.8 0.56 9.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function Mito_fiss_reg PF05308.11 KXZ54703.1 - 0.017 15.2 0.3 0.026 14.6 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Rubrerythrin PF02915.17 KXZ54707.1 - 2.3e-40 138.2 0.0 4.9e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 Rubrerythrin RNA_pol_Rpb5_N PF03871.14 KXZ54707.1 - 0.0083 16.7 0.1 0.2 12.3 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Ferritin_2 PF13668.6 KXZ54707.1 - 0.0096 16.1 0.0 0.5 10.6 0.0 2.4 1 1 1 2 2 2 1 Ferritin-like domain FA_desaturase_2 PF03405.14 KXZ54707.1 - 0.073 11.9 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Fatty acid desaturase GRP PF07172.11 KXZ54709.1 - 2.1 9.1 25.7 5.3 7.8 7.3 3.6 3 0 0 3 3 3 0 Glycine rich protein family PCMT PF01135.19 KXZ54710.1 - 3.2e-25 89.1 0.0 1.1e-24 87.4 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXZ54710.1 - 1.4e-11 44.5 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ54710.1 - 3.5e-08 34.1 0.0 1.5e-07 32.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain BTB PF00651.31 KXZ54710.1 - 3.8e-07 30.3 0.0 1.1e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Methyltransf_12 PF08242.12 KXZ54710.1 - 5.1e-06 27.2 0.0 1.5e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXZ54710.1 - 6e-06 25.9 0.0 9.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KXZ54710.1 - 6.1e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ54710.1 - 6.4e-06 25.8 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KXZ54710.1 - 2.8e-05 24.7 0.0 9.9e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXZ54710.1 - 0.00048 19.5 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 KXZ54710.1 - 0.001 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 KXZ54710.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KXZ54710.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KXZ54710.1 - 0.0086 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa TPMT PF05724.11 KXZ54710.1 - 0.012 15.3 0.0 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) BACK PF07707.15 KXZ54710.1 - 0.041 14.0 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch Methyltransf_18 PF12847.7 KXZ54710.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KXZ54710.1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF948 PF06103.11 KXZ54711.1 - 1.5e-05 25.1 14.1 0.026 14.8 4.3 3.7 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF948) V-SNARE_C PF12352.8 KXZ54711.1 - 2.7e-05 24.4 1.3 0.00012 22.3 0.3 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXZ54711.1 - 0.00014 21.7 5.2 0.0019 18.1 0.1 2.8 3 0 0 3 3 3 1 Sec20 ALIX_LYPXL_bnd PF13949.6 KXZ54711.1 - 0.00029 20.2 0.7 0.00082 18.7 0.7 1.8 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF5339 PF17274.2 KXZ54711.1 - 0.00056 20.7 3.7 0.002 19.0 3.7 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5339) HisK_N PF09385.10 KXZ54711.1 - 0.0011 18.9 5.6 0.023 14.6 0.8 2.9 3 0 0 3 3 3 1 Histidine kinase N terminal Laminin_II PF06009.12 KXZ54711.1 - 0.0015 18.5 8.9 0.4 10.7 0.0 3.1 3 0 0 3 3 3 2 Laminin Domain II FRB_dom PF08771.11 KXZ54711.1 - 0.0042 17.5 0.6 0.07 13.5 0.4 2.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain NPV_P10 PF05531.12 KXZ54711.1 - 0.032 14.7 5.3 0.038 14.4 0.4 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Myb_DNA-bind_4 PF13837.6 KXZ54711.1 - 0.032 14.6 1.9 0.072 13.5 1.9 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DNA_repr_REX1B PF14966.6 KXZ54711.1 - 0.041 14.6 0.8 0.52 11.0 0.0 2.6 3 0 0 3 3 2 0 DNA repair REX1-B CdiI_2 PF18593.1 KXZ54711.1 - 0.068 13.8 0.5 1.6 9.4 0.1 2.8 1 1 2 3 3 3 0 CdiI immunity protein Peptidase_M32 PF02074.15 KXZ54711.1 - 0.07 11.9 3.6 0.12 11.1 3.6 1.3 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF1759 PF03564.15 KXZ54711.1 - 0.087 12.8 1.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) TssO PF17561.2 KXZ54711.1 - 0.22 11.6 2.2 0.75 9.9 0.7 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO Syntaxin-6_N PF09177.11 KXZ54711.1 - 0.28 11.7 3.3 1.1 9.8 0.2 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4455 PF14643.6 KXZ54711.1 - 0.29 9.7 8.0 0.065 11.9 4.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) ING PF12998.7 KXZ54711.1 - 0.39 11.3 3.3 15 6.2 1.2 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding V-SNARE PF05008.15 KXZ54711.1 - 0.46 10.9 5.0 0.39 11.1 1.3 2.6 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF4208 PF13907.6 KXZ54711.1 - 0.47 10.9 5.1 0.53 10.8 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) SGS PF05002.15 KXZ54711.1 - 0.51 10.5 2.9 2.9 8.0 1.7 2.3 2 0 0 2 2 2 0 SGS domain DUF4164 PF13747.6 KXZ54711.1 - 0.63 10.4 4.5 6.9 7.0 0.2 3.3 3 2 0 3 3 2 0 Domain of unknown function (DUF4164) TMPIT PF07851.13 KXZ54711.1 - 0.8 8.9 7.5 9.9 5.3 4.5 2.2 2 0 0 2 2 2 0 TMPIT-like protein Sigma70_ner PF04546.13 KXZ54711.1 - 0.82 9.5 7.1 2.7 7.8 3.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region RmuC PF02646.16 KXZ54711.1 - 1 8.4 8.2 5.7 6.0 1.3 3.0 3 0 0 3 3 3 0 RmuC family Occludin_ELL PF07303.13 KXZ54711.1 - 1.5 9.6 5.7 1.3 9.8 2.1 2.4 2 1 0 2 2 2 0 Occludin homology domain Syntaxin_2 PF14523.6 KXZ54711.1 - 2 8.8 9.5 0.84 10.0 0.5 3.5 3 2 0 3 3 3 0 Syntaxin-like protein eIF3_N PF09440.10 KXZ54711.1 - 3.2 8.2 7.1 28 5.1 3.2 3.0 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain Perilipin PF03036.16 KXZ54711.1 - 4.4 6.2 7.6 1 8.3 1.2 2.6 3 0 0 3 3 3 0 Perilipin family DUF241 PF03087.14 KXZ54711.1 - 5.5 6.8 8.4 4.3 7.1 2.3 2.6 3 0 0 3 3 3 0 Arabidopsis protein of unknown function NYD-SP28 PF14772.6 KXZ54711.1 - 6.8 6.8 12.3 2.1 8.4 8.3 2.1 2 0 0 2 2 2 0 Sperm tail EzrA PF06160.12 KXZ54711.1 - 10 4.2 13.2 1.1 7.4 2.2 2.6 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Methyltransf_11 PF08241.12 KXZ54713.1 - 7.3e-17 61.8 0.0 3.7e-15 56.3 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ54713.1 - 2.9e-13 50.3 0.1 3.2e-05 24.6 0.0 3.6 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ54713.1 - 1.8e-12 47.4 0.0 2.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ54713.1 - 3.4e-09 36.6 0.0 4e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ54713.1 - 9.3e-09 35.0 0.0 5e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXZ54713.1 - 9e-07 29.6 0.0 7.4e-06 26.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Shikimate_DH PF01488.20 KXZ54714.1 - 3e-44 150.4 0.1 5.5e-44 149.6 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_N PF05201.15 KXZ54714.1 - 1.1e-41 142.0 0.0 2.3e-41 141.0 0.0 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain GlutR_dimer PF00745.20 KXZ54714.1 - 3.2e-28 98.0 1.7 4.1e-28 97.7 0.4 1.9 2 0 0 2 2 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 KXZ54714.1 - 2.8e-06 27.8 2.4 8.6e-06 26.3 0.0 2.9 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXZ54714.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 KXZ54714.1 - 0.0023 17.4 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 KXZ54714.1 - 0.0042 17.3 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KXZ54714.1 - 0.0053 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TarH PF02203.15 KXZ54714.1 - 0.0091 15.9 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Tar ligand binding domain homologue OCD_Mu_crystall PF02423.15 KXZ54714.1 - 0.0094 14.9 0.0 0.028 13.3 0.0 1.7 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.18 KXZ54714.1 - 0.01 16.1 0.6 0.042 14.1 0.0 2.3 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.6 KXZ54714.1 - 0.024 15.1 0.3 0.081 13.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXZ54714.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 KXZ54714.1 - 0.035 14.2 0.1 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TPR_2 PF07719.17 KXZ54715.1 - 9.1e-18 62.9 30.3 2.6e-05 24.0 0.5 11.2 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ54715.1 - 6.2e-17 61.9 20.9 1.3e-05 25.6 0.2 7.0 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ54715.1 - 5.2e-12 45.0 29.5 7e-05 22.5 1.2 9.2 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ54715.1 - 7.3e-11 42.2 15.8 0.0099 16.1 0.8 8.2 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ54715.1 - 1.4e-09 37.9 18.8 0.00045 20.7 0.6 8.5 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ54715.1 - 5.8e-09 35.5 21.5 0.0015 18.6 0.6 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ54715.1 - 1.4e-08 35.2 5.9 0.0042 17.7 0.0 5.8 6 1 1 7 7 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ54715.1 - 1.8e-07 31.3 21.9 7.3e-05 22.9 3.5 5.3 3 1 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXZ54715.1 - 7.6e-07 29.4 15.2 0.42 11.6 0.0 9.3 7 4 5 12 12 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ54715.1 - 2e-06 27.4 15.6 1.9 8.7 0.4 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat DUF4810 PF16068.5 KXZ54715.1 - 0.0011 19.5 5.4 0.47 11.0 1.9 4.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4810) GHL5 PF14872.6 KXZ54715.1 - 0.0043 15.2 0.3 0.0066 14.5 0.3 1.1 1 0 0 1 1 1 1 Hypothetical glycoside hydrolase 5 BEX PF04538.12 KXZ54715.1 - 0.013 16.1 0.1 0.098 13.3 0.0 2.2 2 0 0 2 2 2 0 Brain expressed X-linked like family TPR_11 PF13414.6 KXZ54715.1 - 0.018 14.7 1.4 0.018 14.7 1.4 6.9 9 0 0 9 9 8 0 TPR repeat Wzy_C_2 PF11846.8 KXZ54715.1 - 0.022 14.7 1.6 0.86 9.5 0.6 2.8 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Alkyl_sulf_dimr PF14863.6 KXZ54715.1 - 0.041 14.3 0.1 4.2 7.8 0.0 2.8 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Exonuc_VII_L PF02601.15 KXZ54715.1 - 0.069 12.7 0.5 0.15 11.6 0.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_17 PF13431.6 KXZ54715.1 - 0.14 12.6 9.2 44 4.8 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat COQ9 PF08511.11 KXZ54715.1 - 0.15 11.8 0.5 0.78 9.6 0.0 2.3 3 0 0 3 3 2 0 COQ9 TPR_MalT PF17874.1 KXZ54715.1 - 0.36 10.1 3.7 8.7 5.6 0.0 3.7 3 2 2 5 5 5 0 MalT-like TPR region TPR_21 PF09976.9 KXZ54715.1 - 0.54 9.9 12.7 8.8 6.0 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain SNAP PF14938.6 KXZ54715.1 - 0.84 9.0 10.8 1.6 8.1 3.1 3.8 2 2 2 4 4 4 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 KXZ54715.1 - 1 9.5 7.5 84 3.3 0.0 5.0 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KXZ54715.1 - 1.9 8.5 10.4 40 4.3 0.8 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ54715.1 - 5.7 7.1 18.3 1.3 9.2 0.1 5.3 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Prefoldin_2 PF01920.20 KXZ54716.1 - 1.2e-22 79.8 7.2 1.5e-22 79.6 7.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit OmpH PF03938.14 KXZ54716.1 - 0.0013 19.1 5.3 0.031 14.6 0.3 2.2 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) CHASE3 PF05227.13 KXZ54716.1 - 0.0054 16.6 0.9 0.0054 16.6 0.9 2.0 1 1 0 2 2 2 1 CHASE3 domain Prefoldin PF02996.17 KXZ54716.1 - 0.031 14.2 2.6 0.45 10.4 2.6 2.2 1 1 0 1 1 1 0 Prefoldin subunit EAP30 PF04157.16 KXZ54716.1 - 0.055 12.7 1.1 0.16 11.2 0.1 1.9 2 0 0 2 2 2 0 EAP30/Vps36 family Peptidase_S46 PF10459.9 KXZ54716.1 - 0.17 10.5 3.6 0.19 10.3 3.6 1.0 1 0 0 1 1 1 0 Peptidase S46 NPV_P10 PF05531.12 KXZ54716.1 - 0.34 11.4 2.9 1.8 9.1 0.3 2.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 KXZ54716.1 - 0.58 10.5 5.5 0.3 11.4 0.3 2.3 2 1 0 2 2 2 0 Csm1 N-terminal domain PDEase_I PF00233.19 KXZ54717.1 - 5.8e-75 252.1 1.8 1.3e-74 251.0 0.1 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PAS_8 PF13188.7 KXZ54717.1 - 0.00013 21.9 0.0 0.00063 19.7 0.0 2.2 1 0 0 1 1 1 1 PAS domain zf_C2HC_14 PF18574.1 KXZ54717.1 - 0.11 12.4 0.4 0.33 10.8 0.2 2.0 2 0 0 2 2 2 0 C2HC Zing finger domain AAA_11 PF13086.6 KXZ54718.1 - 1.1e-52 179.4 0.1 9.6e-19 68.2 0.1 3.3 3 0 0 3 3 3 3 AAA domain AAA_12 PF13087.6 KXZ54718.1 - 7e-52 176.0 0.0 9.8e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXZ54718.1 - 7.9e-13 48.5 4.3 4.2e-10 39.7 1.1 3.3 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 KXZ54718.1 - 2.6e-08 34.3 0.2 0.0057 17.0 0.1 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KXZ54718.1 - 0.00062 19.6 0.0 0.39 10.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase SEN1_N PF12726.7 KXZ54718.1 - 0.001 17.4 0.0 0.0014 16.9 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal TFIIF_alpha PF05793.12 KXZ54718.1 - 0.0085 14.7 3.9 0.015 13.9 3.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PhoH PF02562.16 KXZ54718.1 - 0.043 13.3 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein YscO-like PF16789.5 KXZ54718.1 - 0.048 13.7 0.1 0.048 13.7 0.1 2.7 3 0 0 3 3 2 0 YscO-like protein AAA_22 PF13401.6 KXZ54718.1 - 0.078 13.2 0.0 17 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 KXZ54718.1 - 0.09 12.6 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXZ54718.1 - 0.14 11.7 0.0 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KXZ54718.1 - 0.17 11.1 0.0 4.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Snapin_Pallidin PF14712.6 KXZ54718.1 - 0.17 12.3 1.5 0.36 11.3 0.1 2.1 2 0 0 2 2 2 0 Snapin/Pallidin PilO PF04350.13 KXZ54718.1 - 0.21 11.7 0.2 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilO GFO_IDH_MocA PF01408.22 KXZ54719.1 - 4.4e-08 34.0 0.1 8.7e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1338 PF07063.13 KXZ54720.1 - 6.6e-63 212.8 0.0 1.9e-62 211.4 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1338) Myosin_tail_1 PF01576.19 KXZ54721.1 - 0.089 10.6 19.9 0.0068 14.3 11.7 1.8 1 1 1 2 2 2 0 Myosin tail BORCS7 PF16088.5 KXZ54721.1 - 0.096 13.0 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 V_ATPase_I PF01496.19 KXZ54721.1 - 0.4 8.5 4.8 0.47 8.3 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KXZ54721.1 - 1.5 8.9 5.4 1 9.4 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 KXZ54721.1 - 2.4 7.4 5.0 7.9 5.7 5.0 1.7 1 1 0 1 1 1 0 FAM76 protein Tropomyosin_1 PF12718.7 KXZ54721.1 - 4.7 7.4 17.6 0.031 14.4 4.4 2.2 1 1 1 2 2 2 0 Tropomyosin like GAS PF13851.6 KXZ54721.1 - 4.8 6.5 17.4 1.4 8.2 11.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 KXZ54721.1 - 8.8 6.3 16.1 2.9 7.9 1.3 2.6 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion RRM_1 PF00076.22 KXZ54722.1 - 3e-07 30.2 0.4 0.00021 21.0 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.23 KXZ54723.1 - 1.2e-13 51.6 13.8 7.1e-09 35.9 5.2 3.8 2 2 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXZ54723.1 - 0.00022 20.9 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Peptidase_M24 PF00557.24 KXZ54724.1 - 5.8e-51 173.2 0.0 1e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXZ54724.1 - 7.3e-25 87.1 0.0 1.3e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Filament PF00038.21 KXZ54725.1 - 0.00068 19.3 16.3 0.0011 18.6 16.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein Sulfatase_C PF14707.6 KXZ54725.1 - 0.21 12.3 0.5 0.61 10.8 0.5 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Surfac_D-trimer PF09006.11 KXZ54725.1 - 0.57 10.1 2.4 1.4 8.8 2.4 1.7 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Spc7 PF08317.11 KXZ54725.1 - 0.73 8.6 12.6 1.2 8.0 12.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Lectin_N PF03954.14 KXZ54725.1 - 1.6 8.5 6.2 1.7 8.4 4.2 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain MatP_C PF17414.2 KXZ54725.1 - 2 8.7 4.9 3.1 8.0 3.3 2.2 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain AAA_13 PF13166.6 KXZ54725.1 - 2.4 6.7 8.8 3.5 6.2 8.8 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 KXZ54725.1 - 4.5 6.3 12.5 11 5.0 12.5 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAT1 PF06391.13 KXZ54725.1 - 9.8 5.9 11.5 16 5.3 11.5 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Mito_carr PF00153.27 KXZ54726.1 - 7.7e-38 128.3 2.1 1.4e-16 60.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein TIG PF01833.24 KXZ54727.1 - 1e-58 195.4 87.0 7.1e-10 38.8 7.3 13.6 14 0 0 14 14 14 10 IPT/TIG domain G8 PF10162.9 KXZ54727.1 - 5.3e-57 191.2 0.0 1.3e-27 96.3 0.0 2.7 2 0 0 2 2 2 2 G8 domain PA14 PF07691.12 KXZ54727.1 - 3.7e-08 33.3 0.4 3.9e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 PA14 domain Beta_helix PF13229.6 KXZ54727.1 - 2.1e-06 27.6 16.8 0.013 15.3 4.0 4.6 2 2 0 2 2 2 2 Right handed beta helix region RNase_T PF00929.24 KXZ54728.1 - 2.9e-08 34.4 0.0 4.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KXZ54728.1 - 0.0074 16.0 0.0 0.028 14.1 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Glyco_hydro_39 PF01229.17 KXZ54728.1 - 0.2 10.2 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 F-box PF00646.33 KXZ54729.1 - 0.028 14.3 0.5 0.069 13.0 0.5 1.6 1 0 0 1 1 1 0 F-box domain MtN3_slv PF03083.16 KXZ54730.1 - 2.4e-25 88.4 4.8 1.5e-13 50.6 0.7 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF2754 PF10953.8 KXZ54730.1 - 0.068 13.4 0.1 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) DUF2070 PF09843.9 KXZ54730.1 - 0.1 10.8 2.8 0.15 10.4 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1129 PF06570.11 KXZ54730.1 - 1.9 7.9 3.7 6.4 6.2 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2012 PF09430.10 KXZ54731.1 - 3.4e-17 62.7 0.0 6.6e-17 61.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KXZ54731.1 - 0.021 14.4 0.0 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein DUF4538 PF15061.6 KXZ54731.1 - 0.048 13.4 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Acatn PF13000.7 KXZ54733.1 - 1.1e-117 393.9 0.0 2.6e-92 310.1 0.0 2.8 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 LysM PF01476.20 KXZ54734.1 - 1e-05 25.5 0.3 3.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 LysM domain Ank_2 PF12796.7 KXZ54736.1 - 8.3e-05 23.1 0.0 0.18 12.4 0.0 3.7 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ54736.1 - 0.00026 21.2 0.1 9.1 6.7 0.0 5.8 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ54736.1 - 0.001 19.6 1.8 7 7.4 0.0 5.1 6 1 0 6 6 6 2 Ankyrin repeats (many copies) DnaJ_C PF01556.18 KXZ54737.1 - 8.5e-15 55.1 0.0 1.2e-09 38.4 0.0 2.2 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.31 KXZ54737.1 - 1.7e-06 28.0 0.0 7.6e-05 22.8 0.0 2.5 2 1 1 3 3 3 2 DnaJ domain ABC_tran PF00005.27 KXZ54738.1 - 1.9e-19 70.6 0.0 2.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ54738.1 - 5.6e-08 33.0 0.0 0.0085 15.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ54738.1 - 2.6e-07 30.3 1.5 0.0016 17.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ54738.1 - 0.00098 18.8 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXZ54738.1 - 0.015 15.2 0.2 0.032 14.1 0.2 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_13 PF13166.6 KXZ54738.1 - 0.027 13.1 0.1 0.04 12.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ54738.1 - 0.059 13.9 0.2 0.15 12.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXZ54738.1 - 0.08 13.4 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXZ54738.1 - 0.08 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXZ54738.1 - 0.16 11.5 0.2 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXZ54738.1 - 0.17 12.2 1.7 3.3 8.0 1.7 2.2 1 1 0 1 1 1 0 AAA domain Ferrochelatase PF00762.19 KXZ54739.1 - 2e-112 375.4 0.0 2.4e-112 375.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 KXZ54739.1 - 0.00017 21.9 0.0 0.072 13.4 0.0 2.6 2 0 0 2 2 2 2 CbiX Chloroa_b-bind PF00504.21 KXZ54739.1 - 0.0013 19.3 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Glycos_trans_3N PF02885.17 KXZ54739.1 - 0.39 10.6 0.1 0.39 10.6 0.1 2.3 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain NGP1NT PF08153.12 KXZ54741.1 - 3.4e-46 156.6 0.6 5.4e-46 156.0 0.6 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KXZ54741.1 - 8.4e-15 54.9 0.0 3.2e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ54741.1 - 0.00014 21.5 0.0 0.0064 16.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXZ54741.1 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KXZ54741.1 - 0.11 12.1 0.0 0.91 9.0 0.0 2.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Arf PF00025.21 KXZ54741.1 - 0.11 12.0 0.1 4 6.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 KXZ54741.1 - 0.2 11.7 0.2 3.3 7.7 0.0 2.6 2 1 1 3 3 3 0 Dynamin family SDA1 PF05285.12 KXZ54741.1 - 6 6.2 17.0 15 4.9 17.0 1.7 1 0 0 1 1 1 0 SDA1 Ank_2 PF12796.7 KXZ54742.1 - 5.3e-09 36.5 0.0 0.012 16.2 0.0 3.8 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54742.1 - 6.7e-09 36.1 2.9 0.2 12.3 0.3 5.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54742.1 - 0.0016 18.7 0.8 3.1e+02 2.5 0.0 6.6 7 1 1 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ54742.1 - 0.0082 16.4 6.8 8.1 6.9 0.0 5.2 3 2 3 6 6 6 2 Ankyrin repeats (many copies) DEAD PF00270.29 KXZ54745.1 - 3.2e-17 62.9 0.0 5.5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ54745.1 - 1.9e-13 50.7 0.0 4.9e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CW PF07496.15 KXZ54745.1 - 0.00099 19.1 2.0 0.0018 18.3 2.0 1.4 1 0 0 1 1 1 1 CW-type Zinc Finger DUF2232 PF09991.9 KXZ54746.1 - 1.5e-08 34.2 8.5 1.5e-08 34.2 8.5 2.0 1 1 1 2 2 2 1 Predicted membrane protein (DUF2232) SHOCT PF09851.9 KXZ54747.1 - 0.0041 16.8 1.6 0.32 10.8 0.4 2.7 2 0 0 2 2 2 1 Short C-terminal domain Lar_restr_allev PF14354.6 KXZ54747.1 - 0.011 16.1 1.4 0.03 14.7 1.4 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 KXZ54747.1 - 0.022 14.2 1.4 6.2 6.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Rtf2 PF04641.12 KXZ54747.1 - 0.034 13.5 1.3 0.055 12.8 1.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger zf-CSL PF05207.13 KXZ54747.1 - 0.084 12.6 0.3 0.3 10.8 0.1 1.9 2 0 0 2 2 2 0 CSL zinc finger zinc_ribbon_2 PF13240.6 KXZ54747.1 - 0.59 9.9 3.4 2.8 7.8 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Metallophos PF00149.28 KXZ54749.1 - 6.3e-05 23.6 0.0 0.0016 19.0 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Nucleotid_trans PF03407.16 KXZ54750.1 - 1.8e-11 44.4 0.0 2.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase UPF0227 PF05728.12 KXZ54750.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Nucleotid_trans PF03407.16 KXZ54751.1 - 3.9e-14 53.1 0.3 4.8e-14 52.8 0.3 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CortBP2 PF09727.9 KXZ54751.1 - 0.084 12.8 0.2 0.51 10.2 0.2 1.9 1 1 0 1 1 1 0 Cortactin-binding protein-2 Cpn60_TCP1 PF00118.24 KXZ54753.1 - 1.4e-100 337.3 17.2 3e-100 336.2 17.2 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DJ-1_PfpI PF01965.24 KXZ54753.1 - 0.012 15.4 0.6 0.69 9.7 0.1 2.8 2 0 0 2 2 2 0 DJ-1/PfpI family DUF4355 PF14265.6 KXZ54753.1 - 0.63 10.3 4.7 1.7 8.9 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Snapin_Pallidin PF14712.6 KXZ54754.1 - 0.026 15.0 2.6 0.045 14.2 2.6 1.4 1 1 0 1 1 1 0 Snapin/Pallidin SKA2 PF16740.5 KXZ54754.1 - 0.028 14.2 2.6 0.044 13.6 2.6 1.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Cluap1 PF10234.9 KXZ54754.1 - 0.059 12.8 1.4 0.077 12.4 1.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Cep57_MT_bd PF06657.13 KXZ54754.1 - 0.1 13.0 2.0 0.22 12.0 2.0 1.5 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DCP1 PF06058.13 KXZ54755.1 - 3.7e-25 88.1 0.1 5.3e-25 87.6 0.1 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family DnaJ_CXXCXGXG PF00684.19 KXZ54756.1 - 0.0019 18.5 0.6 0.0049 17.2 0.6 1.7 1 1 0 1 1 1 1 DnaJ central domain zf-C2HC PF01530.18 KXZ54756.1 - 0.026 14.7 0.6 1.3 9.3 1.0 2.4 2 0 0 2 2 2 0 Zinc finger, C2HC type Anti-TRAP PF15777.5 KXZ54756.1 - 0.026 14.5 1.5 0.034 14.1 0.3 1.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein NCD3G PF07562.14 KXZ54756.1 - 0.041 13.9 1.0 0.073 13.0 0.6 1.6 1 1 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Ank_2 PF12796.7 KXZ54757.1 - 2.4e-08 34.5 2.7 0.0061 17.1 0.4 4.8 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54757.1 - 1.1e-05 25.9 4.4 0.28 11.8 0.1 6.4 7 2 0 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54757.1 - 4.9e-05 23.4 4.9 1.5 9.6 0.0 6.5 6 1 1 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KXZ54757.1 - 0.00077 19.7 7.1 0.63 10.4 0.2 5.7 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ad_Cy_reg PF16701.5 KXZ54757.1 - 0.15 11.8 9.9 0.31 10.8 0.1 4.7 4 2 2 6 6 6 0 Adenylate cyclase regulatory domain Apolipo_F PF15148.6 KXZ54757.1 - 0.85 9.1 4.3 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein F zf-DNL PF05180.12 KXZ54758.1 - 3e-12 46.3 0.1 4.5e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CW PF07496.15 KXZ54758.1 - 0.16 12.0 0.8 0.38 10.8 0.8 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PPTA PF01239.22 KXZ54759.1 - 9.8e-34 114.1 11.7 5.7e-08 32.2 0.2 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat MID_MedPIWI PF18296.1 KXZ54761.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 MID domain of medPIWI FBPase_glpX PF03320.13 KXZ54762.1 - 3.7e-142 472.7 0.7 4.2e-142 472.5 0.7 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded TRP PF06011.12 KXZ54763.1 - 6.1e-09 35.1 6.3 1.1e-08 34.3 6.3 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Beta_helix PF13229.6 KXZ54763.1 - 6.9e-08 32.5 3.8 6.9e-08 32.5 3.8 3.6 1 1 2 3 3 3 2 Right handed beta helix region Ank_2 PF12796.7 KXZ54764.1 - 7.1e-12 45.8 0.4 4.8e-05 23.9 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54764.1 - 4.3e-10 39.9 2.8 0.34 11.5 0.0 5.9 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54764.1 - 1.1e-05 25.5 2.9 21 6.1 0.0 6.8 6 1 1 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 KXZ54764.1 - 1 9.7 8.0 10 6.6 0.1 5.2 5 1 1 6 6 6 0 Ankyrin repeats (many copies) GET2 PF08690.10 KXZ54765.1 - 0.53 9.9 1.5 1 9.0 1.5 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 RcbX PF02341.15 KXZ54766.1 - 2.7e-19 69.5 0.0 5e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 RbcX protein IMS PF00817.20 KXZ54766.1 - 1.7e-14 54.1 0.1 3.3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family CAMSAP_CH PF11971.8 KXZ54766.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Pkinase PF00069.25 KXZ54767.1 - 3.9e-56 190.3 0.0 1.1e-41 143.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54767.1 - 4.6e-33 114.6 0.0 6.5e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ54767.1 - 2.3e-05 23.4 4.2 0.001 17.9 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 KXZ54767.1 - 0.0015 17.9 0.0 0.0049 16.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 KXZ54767.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Macro PF01661.21 KXZ54768.1 - 1.2e-39 135.0 0.2 3.3e-39 133.6 0.0 1.8 2 0 0 2 2 2 1 Macro domain GBP PF02263.19 KXZ54769.1 - 0.00026 20.3 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KXZ54769.1 - 0.016 13.4 0.0 0.025 12.8 0.0 1.3 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) FAST_1 PF06743.15 KXZ54771.1 - 8e-05 22.5 0.1 6 6.9 0.0 4.1 3 1 0 3 3 3 3 FAST kinase-like protein, subdomain 1 Tegument_dsDNA PF12818.7 KXZ54771.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 dsDNA viral tegument protein Spt20 PF12090.8 KXZ54773.1 - 0.77 9.3 3.9 1.6 8.3 3.9 1.4 1 0 0 1 1 1 0 Spt20 family CwfJ_C_1 PF04677.15 KXZ54774.1 - 4.5e-23 81.4 0.0 7.4e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 KXZ54774.1 - 3.3e-11 42.8 0.0 7.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 KXZ54774.1 - 7e-09 36.5 0.0 1.4e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Cofilin_ADF PF00241.20 KXZ54775.1 - 1.8e-32 111.7 0.1 2e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2004 PF09406.10 KXZ54775.1 - 0.036 14.4 0.1 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) VGPC1_C PF16799.5 KXZ54776.1 - 0.065 13.2 3.3 0.088 12.8 2.2 1.7 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 FAP PF07174.11 KXZ54776.1 - 0.52 9.7 23.8 0.67 9.4 23.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) NRBF2 PF08961.10 KXZ54776.1 - 2.2 7.8 19.0 15 5.1 5.5 2.7 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Phosphorylase PF00343.20 KXZ54777.1 - 0 1021.0 0.0 0 1020.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase p450 PF00067.22 KXZ54778.1 - 8.2e-64 216.0 0.0 1.1e-55 189.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 HTH_37 PF13744.6 KXZ54778.1 - 0.21 11.5 0.3 0.58 10.2 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.22 KXZ54779.1 - 3.8e-15 55.6 0.0 4.4e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXZ54780.1 - 7e-48 163.5 0.0 3.1e-47 161.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ENT PF03735.14 KXZ54781.1 - 0.09 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 ENT domain fn3 PF00041.21 KXZ54782.1 - 1.9e-87 287.7 0.0 3.6e-12 46.4 0.0 9.8 8 2 1 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KXZ54782.1 - 1.4e-34 118.5 0.0 0.00013 22.5 0.0 9.5 8 2 1 9 9 9 7 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KXZ54782.1 - 2.4e-06 28.0 0.3 9.2 6.9 0.0 5.8 5 0 0 5 5 5 2 PhoD-like phosphatase, N-terminal domain DUF2369 PF10179.9 KXZ54782.1 - 9.5e-05 22.7 0.0 21 5.6 0.0 5.1 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) Reeler PF02014.16 KXZ54782.1 - 0.23 12.2 0.5 8.2 7.2 0.0 3.3 4 0 0 4 4 4 0 Reeler domain TFIIA PF03153.13 KXZ54786.1 - 5.7 6.8 6.1 6.9 6.6 6.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit E1_dh PF00676.20 KXZ54787.1 - 1.3e-110 369.0 0.6 1.7e-110 368.7 0.6 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXZ54787.1 - 8e-07 28.5 0.1 1.7e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KXZ54787.1 - 0.00011 22.0 2.9 0.00012 22.0 1.1 1.8 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TMF_TATA_bd PF12325.8 KXZ54788.1 - 4.8e-07 30.0 0.1 6.2e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Rx_N PF18052.1 KXZ54788.1 - 0.018 15.3 0.1 0.027 14.8 0.1 1.3 1 0 0 1 1 1 0 Rx N-terminal domain Pkinase PF00069.25 KXZ54789.1 - 5.9e-45 153.7 0.0 1.2e-44 152.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54789.1 - 5.6e-12 45.5 0.0 1.1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ54789.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ54789.1 - 0.099 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Rep_fac_C PF08542.11 KXZ54790.1 - 6.9e-19 68.1 0.0 6.4e-18 65.0 0.0 2.3 1 1 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXZ54790.1 - 1.3e-13 51.5 0.0 2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXZ54790.1 - 3e-12 46.6 0.0 8.2e-10 38.7 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KXZ54790.1 - 1.5e-05 25.0 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ54790.1 - 3e-05 24.3 0.0 0.012 15.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXZ54790.1 - 3.4e-05 23.3 0.0 0.00032 20.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ54790.1 - 4.2e-05 24.0 0.0 0.0016 18.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KXZ54790.1 - 0.00024 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ54790.1 - 0.00027 20.8 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF5119 PF17145.4 KXZ54790.1 - 0.00033 20.7 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5119) Rad17 PF03215.15 KXZ54790.1 - 0.00034 20.6 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 KXZ54790.1 - 0.00087 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXZ54790.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KXZ54790.1 - 0.0025 17.4 0.1 0.0082 15.7 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXZ54790.1 - 0.0028 18.0 0.1 0.025 14.9 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KXZ54790.1 - 0.0038 17.5 0.0 0.0094 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain TniB PF05621.11 KXZ54790.1 - 0.0046 16.4 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 KXZ54790.1 - 0.006 16.6 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 KXZ54790.1 - 0.011 15.5 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 KXZ54790.1 - 0.018 15.6 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ54790.1 - 0.02 15.4 0.0 0.053 14.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KXZ54790.1 - 0.024 14.4 0.1 0.096 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KXZ54790.1 - 0.033 13.2 0.0 0.056 12.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KXZ54790.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KXZ54790.1 - 0.034 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXZ54790.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KXZ54790.1 - 0.08 12.3 0.1 0.52 9.6 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_28 PF13521.6 KXZ54790.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXZ54790.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SNF2_N PF00176.23 KXZ54790.1 - 0.13 11.0 0.1 8.7 5.0 0.1 2.1 1 1 1 2 2 2 0 SNF2 family N-terminal domain KTI12 PF08433.10 KXZ54790.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SSE PF00437.20 KXZ54790.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Ank_2 PF12796.7 KXZ54793.1 - 1.6e-46 156.8 9.0 1.8e-13 50.8 0.0 4.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ54793.1 - 1.3e-37 126.6 6.7 8.3e-05 22.9 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KXZ54793.1 - 6.7e-33 112.3 14.2 2.2e-08 34.2 0.2 7.8 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ54793.1 - 9.1e-31 105.8 1.2 9.1e-07 29.3 0.0 5.5 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54793.1 - 1.9e-27 92.3 4.0 0.001 19.4 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat Flg_hook PF02120.16 KXZ54793.1 - 0.78 9.7 3.0 0.51 10.3 0.2 2.1 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK DUF1707 PF08044.11 KXZ54793.1 - 7.7 6.7 10.2 1.4 9.0 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) Ank_2 PF12796.7 KXZ54794.1 - 8e-44 148.1 0.0 2.3e-16 60.2 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ54794.1 - 4.2e-34 116.2 3.0 1.5e-05 25.2 0.0 7.2 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KXZ54794.1 - 3.5e-32 109.4 2.3 4.3e-05 23.8 0.0 7.3 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KXZ54794.1 - 2e-30 101.4 0.8 0.00033 20.9 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 KXZ54794.1 - 5.7e-30 103.3 0.2 1.9e-08 34.7 0.0 5.0 3 2 1 4 4 4 4 Ankyrin repeats (many copies) HTH_3 PF01381.22 KXZ54794.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix RRM_2 PF04059.12 KXZ54796.1 - 1.1e-48 163.3 0.4 1.9e-48 162.6 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KXZ54796.1 - 1.8e-16 59.7 1.9 1.6e-07 31.1 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ZYG-11_interact PF05884.12 KXZ54796.1 - 0.0041 16.6 9.9 0.0068 15.9 9.9 1.3 1 0 0 1 1 1 1 Interactor of ZYG-11 RRM_5 PF13893.6 KXZ54796.1 - 0.016 14.8 0.2 0.99 9.0 0.0 3.1 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.7 KXZ54797.1 - 3.3e-23 81.4 0.2 6.4e-09 36.0 0.1 4.1 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ54797.1 - 4.3e-18 64.8 8.3 1.5e-05 24.7 0.2 4.9 4 1 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 KXZ54797.1 - 2.6e-11 43.4 0.0 1.7e-09 37.4 0.1 2.5 2 1 0 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 KXZ54797.1 - 1.1e-10 40.5 2.2 3.3 8.6 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KXZ54797.1 - 2e-06 27.4 3.3 0.72 10.1 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat tRNA_edit PF04073.15 KXZ54798.1 - 1e-05 25.6 0.0 3.6e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain AAA_lid_2 PF17863.1 KXZ54798.1 - 0.0032 17.3 1.3 0.68 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA lid domain GRIP PF01465.20 KXZ54799.1 - 0.13 12.2 0.0 2.5 8.1 0.0 2.5 2 1 0 2 2 2 0 GRIP domain FAST_1 PF06743.15 KXZ54799.1 - 0.14 12.2 0.0 0.44 10.5 0.0 1.8 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 1 MCM_OB PF17207.3 KXZ54800.1 - 1.5e-39 134.7 0.1 2.5e-39 134.0 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KXZ54800.1 - 7.5e-19 68.5 18.9 1.7e-18 67.4 18.9 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KXZ54800.1 - 4.6e-17 62.5 0.0 8.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain MFS_1 PF07690.16 KXZ54800.1 - 3.6e-13 49.2 5.1 5e-13 48.7 5.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ54800.1 - 4.3e-07 29.2 0.4 5.9e-07 28.7 0.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Zn-ribbon_8 PF09723.10 KXZ54800.1 - 0.0078 16.3 0.8 0.017 15.3 0.8 1.6 1 0 0 1 1 1 1 Zinc ribbon domain Pellino PF04710.14 KXZ54800.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Pellino BTB PF00651.31 KXZ54801.1 - 9.4e-19 67.7 0.0 1.8e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 KXZ54801.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 KXZ54802.1 - 3.7e-18 65.8 0.0 5.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXZ54803.1 - 5e-16 58.9 0.0 8.4e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 KXZ54803.1 - 1.5e-05 25.1 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 MATH domain USP7_ICP0_bdg PF12436.8 KXZ54806.1 - 7.8e-56 189.1 0.0 6.7e-55 186.0 0.0 2.6 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 KXZ54806.1 - 2.3e-47 161.6 0.0 3.7e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KXZ54806.1 - 2.7e-27 95.8 0.0 1.7e-25 89.9 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 KXZ54806.1 - 8.5e-21 74.9 0.0 3.4e-20 72.9 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KXZ54806.1 - 9.9e-10 38.6 0.0 2.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 MATH domain ubiquitin PF00240.23 KXZ54806.1 - 7.6e-06 25.6 0.0 0.023 14.4 0.0 3.8 4 0 0 4 4 4 1 Ubiquitin family TBK1_ULD PF18396.1 KXZ54806.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain RRM_1 PF00076.22 KXZ54807.1 - 7.4e-21 73.8 0.0 4.2e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ54807.1 - 1.6e-05 24.5 0.0 0.0084 15.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXZ54807.1 - 0.0017 18.3 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KXZ54807.1 - 0.013 15.6 0.1 0.79 9.8 0.0 2.5 2 1 0 2 2 2 0 Limkain b1 RRM_occluded PF16842.5 KXZ54807.1 - 0.075 12.9 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif HHH_2 PF12826.7 KXZ54810.1 - 2.6e-13 49.8 0.1 4.1e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KXZ54810.1 - 0.00072 20.1 0.1 0.0017 18.9 0.1 1.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 KXZ54810.1 - 0.035 14.0 0.1 0.089 12.7 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fra10Ac1 PF09725.9 KXZ54811.1 - 2.4e-47 160.1 1.1 3.6e-47 159.5 1.1 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 BTB PF00651.31 KXZ54811.1 - 1.5e-15 57.4 0.0 2.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 KXZ54811.1 - 2.8e-07 30.7 0.0 5.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 MATH domain Glyco_hydro_47 PF01532.20 KXZ54812.1 - 2.4e-133 445.4 0.0 3.3e-133 444.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Mito_fiss_reg PF05308.11 KXZ54812.1 - 2.1 8.4 3.2 3.7 7.5 3.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXZ54812.1 - 7.4 6.0 6.3 12 5.3 6.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HATPase_c_3 PF13589.6 KXZ54813.1 - 2.8e-09 36.9 0.0 4.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KXZ54813.1 - 1.3e-07 31.3 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KXZ54813.1 - 8.8e-06 26.2 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase T3SS_needle_reg PF09025.10 KXZ54814.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator MscS_porin PF12795.7 KXZ54815.1 - 0.00044 19.9 52.0 0.00044 19.9 52.0 24.6 6 3 17 25 25 25 6 Mechanosensitive ion channel porin domain Pox_A_type_inc PF04508.12 KXZ54815.1 - 0.0005 19.8 29.4 0.061 13.2 0.1 10.7 12 0 0 12 12 12 3 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 KXZ54815.1 - 0.0016 18.5 6.7 0.0016 18.5 6.7 29.8 12 4 14 28 28 28 11 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 KXZ54815.1 - 0.011 14.9 0.1 0.011 14.9 0.1 17.9 7 4 9 18 18 18 0 Myosin-like coiled-coil protein DUF4763 PF15960.5 KXZ54816.1 - 0.00022 20.6 0.5 0.00022 20.6 0.5 3.3 1 1 1 3 3 3 2 Domain of unknown function (DUF4763) FlaC_arch PF05377.11 KXZ54816.1 - 0.28 11.6 0.6 63 4.1 0.0 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Filament PF00038.21 KXZ54816.1 - 1.7 8.1 42.8 0.55 9.7 10.0 2.7 1 1 2 3 3 3 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 KXZ54816.1 - 4.6 7.4 46.1 0.18 12.0 7.5 3.4 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF1772 PF08592.11 KXZ54817.1 - 3.6e-07 30.6 1.3 4.3e-07 30.3 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ACT_7 PF13840.6 KXZ54817.1 - 0.1 12.4 0.2 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 ACT domain CASP_C PF08172.12 KXZ54818.1 - 3.5e-48 164.2 20.3 1.4e-46 158.9 0.0 5.2 3 2 2 6 6 6 2 CASP C terminal FtsK_alpha PF17854.1 KXZ54818.1 - 0.2 11.8 1.7 0.8 9.9 0.0 2.8 3 0 0 3 3 3 0 FtsK alpha domain Not3 PF04065.15 KXZ54818.1 - 0.71 9.3 16.6 0.42 10.0 8.0 4.2 3 1 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Pox_A_type_inc PF04508.12 KXZ54818.1 - 0.87 9.6 6.6 21 5.2 0.4 4.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Fez1 PF06818.15 KXZ54818.1 - 2.3 8.6 46.0 3.6 8.0 0.8 4.6 3 2 1 4 4 4 0 Fez1 WD40_alt PF14077.6 KXZ54818.1 - 2.9 7.8 4.1 3.3 7.7 0.0 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif STN1_2 PF09170.10 KXZ54818.1 - 3.8 7.7 6.2 13 5.9 0.3 3.3 3 0 0 3 3 3 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 LRR_8 PF13855.6 KXZ54819.1 - 0.00026 20.7 0.7 0.0015 18.3 0.1 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 KXZ54819.1 - 0.11 13.1 0.1 91 4.2 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 KXZ54819.1 - 0.14 12.6 0.0 14 6.2 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Form_Nir_trans PF01226.17 KXZ54820.1 - 8.3e-71 238.1 18.1 9.5e-71 237.9 18.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Peptidase_M14 PF00246.24 KXZ54822.1 - 1.9e-36 126.4 0.0 2.5e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.8 KXZ54822.1 - 2e-08 34.0 0.0 2.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 KXZ54822.1 - 0.019 14.1 2.4 0.061 12.4 2.2 1.9 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family CarboxypepD_reg PF13620.6 KXZ54822.1 - 0.035 14.4 0.9 0.091 13.0 0.9 1.8 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain PIH1_CS PF18201.1 KXZ54824.1 - 8.8e-17 61.3 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 KXZ54824.1 - 0.0051 16.3 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA TPR_2 PF07719.17 KXZ54825.1 - 1.8e-30 102.5 3.9 0.017 15.2 0.0 12.5 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ54825.1 - 9.8e-28 94.8 7.4 0.0012 18.6 0.0 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ54825.1 - 1.4e-27 95.7 4.0 2.6e-06 27.6 0.0 7.8 5 3 3 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ54825.1 - 1.8e-23 82.8 0.0 0.0054 17.2 0.1 7.6 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ54825.1 - 3.1e-20 70.6 14.9 0.00038 20.5 0.0 10.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ54825.1 - 2.1e-19 69.9 0.1 0.0076 16.9 0.0 7.7 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ54825.1 - 4.5e-18 64.6 6.6 0.2 12.4 0.0 11.5 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ54825.1 - 2.8e-15 55.7 0.0 1.9 9.5 0.0 9.4 6 4 4 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ54825.1 - 2.4e-14 52.7 0.0 0.0017 18.0 0.0 7.9 5 1 3 8 8 8 2 TPR repeat TPR_7 PF13176.6 KXZ54825.1 - 1.2e-13 50.0 7.7 1 9.5 0.0 10.3 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ54825.1 - 6.4e-11 41.8 11.2 0.98 9.4 0.1 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ54825.1 - 1.9e-09 37.2 6.2 1.1 9.8 0.0 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ54825.1 - 7.9e-08 32.4 3.1 1.5 9.1 0.2 6.1 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KXZ54825.1 - 3.2e-07 29.9 0.6 0.0023 17.2 0.2 3.5 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 KXZ54825.1 - 1.1e-06 28.5 5.0 0.00059 19.6 0.2 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KXZ54825.1 - 2.1e-06 27.8 0.0 10 6.3 0.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 KXZ54825.1 - 1.6e-05 24.0 8.9 0.88 8.4 0.0 5.5 3 2 2 6 6 6 1 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 KXZ54825.1 - 3.3e-05 22.8 0.3 0.00045 19.1 0.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) DUF4810 PF16068.5 KXZ54825.1 - 4.3e-05 24.0 1.3 0.14 12.7 0.0 5.2 6 0 0 6 6 5 1 Domain of unknown function (DUF4810) TPR_MalT PF17874.1 KXZ54825.1 - 9.2e-05 22.0 2.0 1.7 7.9 0.0 4.5 4 1 1 5 5 5 1 MalT-like TPR region TPR_3 PF07720.12 KXZ54825.1 - 0.0056 16.6 7.5 1.8 8.7 0.1 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ54825.1 - 0.0065 17.0 5.0 3.5 8.5 0.2 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ54825.1 - 0.062 13.6 1.8 12 6.4 0.0 4.7 4 1 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 KXZ54825.1 - 0.079 13.4 2.7 50 4.3 0.0 4.3 4 1 0 4 4 4 0 Bacterial transcriptional activator domain DUF2225 PF09986.9 KXZ54825.1 - 0.86 9.3 6.6 8.1 6.1 0.2 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) EspB PF05802.11 KXZ54825.1 - 1.4 8.8 4.9 0.37 10.7 0.2 2.1 2 0 0 2 2 2 0 Enterobacterial EspB protein HemY_N PF07219.13 KXZ54825.1 - 3.1 8.0 9.9 2.8 8.2 0.1 3.9 3 1 1 4 4 4 0 HemY protein N-terminus ChuX_HutX PF06228.13 KXZ54826.1 - 6.9e-05 22.6 0.0 8.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX ubiquitin PF00240.23 KXZ54827.1 - 0.00014 21.6 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KXZ54827.1 - 0.0017 18.4 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF1664 PF07889.12 KXZ54828.1 - 0.00015 21.7 1.6 3.3 7.7 0.0 3.7 4 0 0 4 4 3 1 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 KXZ54828.1 - 0.0011 19.5 0.5 10 6.8 0.0 3.8 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Snapin_Pallidin PF14712.6 KXZ54828.1 - 0.0015 18.9 5.4 5 7.6 0.0 3.6 3 1 0 3 3 3 0 Snapin/Pallidin Tup_N PF08581.10 KXZ54828.1 - 0.0018 18.6 3.9 0.34 11.3 0.2 2.9 3 0 0 3 3 2 1 Tup N-terminal AATF-Che1 PF13339.6 KXZ54828.1 - 0.0037 18.0 0.8 1.6 9.4 0.0 2.8 2 1 1 3 3 3 1 Apoptosis antagonizing transcription factor JAKMIP_CC3 PF16034.5 KXZ54828.1 - 0.017 15.1 10.9 0.22 11.4 0.1 3.4 3 1 0 3 3 3 0 JAKMIP CC3 domain RmuC PF02646.16 KXZ54828.1 - 0.017 14.3 9.7 0.037 13.2 0.0 3.5 3 1 1 4 4 4 0 RmuC family Bacillus_HBL PF05791.11 KXZ54828.1 - 0.017 15.0 5.9 1.3 8.9 0.1 3.0 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Phage_GP20 PF06810.11 KXZ54828.1 - 0.019 14.8 12.4 0.32 10.8 0.8 3.5 3 1 0 3 3 3 0 Phage minor structural protein GP20 RIC3 PF15361.6 KXZ54828.1 - 0.031 14.7 3.7 3 8.2 0.2 3.2 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4618 PF15397.6 KXZ54828.1 - 0.032 13.6 3.9 4.1 6.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) zf-C4H2 PF10146.9 KXZ54828.1 - 0.033 14.5 1.7 0.91 9.8 0.0 2.9 2 1 1 3 3 3 0 Zinc finger-containing protein APG6_N PF17675.1 KXZ54828.1 - 0.058 13.9 12.1 0.29 11.7 2.0 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KXZ54828.1 - 0.06 13.8 4.1 14 6.3 0.2 3.6 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Sec5 PF15469.6 KXZ54828.1 - 0.074 12.8 2.3 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec5 GLTP PF08718.11 KXZ54828.1 - 0.14 12.4 3.9 0.082 13.2 1.1 2.2 2 1 0 2 2 1 0 Glycolipid transfer protein (GLTP) MtrG PF04210.13 KXZ54828.1 - 0.17 11.7 0.1 6.4 6.7 0.0 2.9 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Prefoldin PF02996.17 KXZ54828.1 - 0.25 11.2 9.7 0.077 12.9 1.3 3.7 3 1 0 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.9 KXZ54828.1 - 0.34 11.2 8.8 2.9 8.3 0.5 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hemerythrin PF01814.23 KXZ54828.1 - 0.42 11.2 7.4 20 5.8 0.3 4.0 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain Seryl_tRNA_N PF02403.22 KXZ54828.1 - 0.52 10.6 13.8 15 5.9 2.4 3.9 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain GA PF01468.17 KXZ54828.1 - 0.73 10.2 9.8 0.78 10.1 4.3 2.8 2 1 1 3 3 2 0 GA module GAS PF13851.6 KXZ54828.1 - 0.74 9.1 14.6 0.087 12.2 2.5 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 KXZ54828.1 - 0.74 9.9 6.2 33 4.6 0.7 3.4 4 0 0 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Herpes_UL17 PF04559.12 KXZ54828.1 - 0.88 8.3 11.4 0.038 12.8 4.9 1.7 1 1 0 2 2 2 0 Herpesvirus UL17 protein OmpH PF03938.14 KXZ54828.1 - 0.89 9.9 16.8 11 6.4 1.8 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) EzrA PF06160.12 KXZ54828.1 - 0.91 7.6 5.5 4.6 5.3 0.0 2.5 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA TMPIT PF07851.13 KXZ54828.1 - 1.1 8.4 2.6 26 3.9 0.1 2.8 3 0 0 3 3 3 0 TMPIT-like protein Lebercilin PF15619.6 KXZ54828.1 - 1.1 8.9 9.9 3.5 7.2 1.1 3.3 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease YabA PF06156.13 KXZ54828.1 - 1.2 9.8 3.8 24 5.6 0.3 3.4 2 1 1 3 3 3 0 Initiation control protein YabA Wbp11 PF09429.10 KXZ54828.1 - 1.5 9.2 0.0 1.5 9.2 0.0 3.8 4 1 0 4 4 4 0 WW domain binding protein 11 PEP-utilisers_N PF05524.13 KXZ54828.1 - 2 8.6 20.0 8.5 6.6 0.2 3.7 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal Rab5-bind PF09311.11 KXZ54828.1 - 2.2 7.6 8.1 6.8 6.0 0.7 2.2 2 0 0 2 2 2 0 Rabaptin-like protein AAA_13 PF13166.6 KXZ54828.1 - 2.7 6.5 6.8 6.5 5.3 0.8 2.1 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.12 KXZ54828.1 - 3.4 7.7 8.4 5.3 7.1 0.2 3.2 3 0 0 3 3 3 0 Laminin Domain II Prefoldin_2 PF01920.20 KXZ54828.1 - 3.8 7.5 10.0 10 6.1 2.6 3.6 4 1 0 4 4 3 0 Prefoldin subunit DUF2203 PF09969.9 KXZ54828.1 - 4.3 8.1 8.3 3.7 8.3 0.2 3.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) GrpE PF01025.19 KXZ54828.1 - 5.1 6.7 12.5 2.9 7.5 0.6 3.2 3 0 0 3 3 3 0 GrpE CCDC-167 PF15188.6 KXZ54828.1 - 5.5 7.4 7.6 5.1 7.5 0.5 3.1 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Cnn_1N PF07989.11 KXZ54828.1 - 6.5 7.0 8.4 6.5 7.0 2.4 3.2 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 BAF1_ABF1 PF04684.13 KXZ54828.1 - 8.3 5.3 7.1 7.3 5.5 5.5 1.7 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Rx_N PF18052.1 KXZ54829.1 - 0.0027 17.9 9.1 1.5e+02 2.7 0.4 9.4 11 0 0 11 11 11 0 Rx N-terminal domain DUF3323 PF11796.8 KXZ54829.1 - 0.19 11.6 7.3 0.67 9.8 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function N-terminus (DUF3323) ZapB PF06005.12 KXZ54829.1 - 0.57 10.7 4.8 10 6.6 0.3 3.5 2 1 0 2 2 2 0 Cell division protein ZapB DUF4618 PF15397.6 KXZ54829.1 - 2.7 7.4 5.0 14 5.0 0.6 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4618) Cnn_1N PF07989.11 KXZ54829.1 - 9.2 6.5 6.2 4.4 7.5 0.1 3.6 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 VCBS PF13517.6 KXZ54830.1 - 3e-10 40.5 9.1 0.005 17.4 0.0 5.1 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KXZ54830.1 - 1e-09 38.3 21.8 0.0039 17.3 0.0 4.9 3 1 1 4 4 4 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 KXZ54830.1 - 0.0017 17.7 1.4 3.6 6.9 0.0 3.4 3 1 0 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region RTBV_P12 PF06361.11 KXZ54831.1 - 4.6 7.7 4.8 6.8 7.1 0.0 2.9 3 1 0 3 3 3 0 Rice tungro bacilliform virus P12 protein Pkinase PF00069.25 KXZ54832.1 - 1.4e-60 204.9 0.0 1.9e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 KXZ54832.1 - 1.5e-26 89.9 5.9 2.3e-06 26.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXZ54832.1 - 1.5e-23 82.4 3.8 9.1e-06 25.4 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 KXZ54832.1 - 2.1e-23 82.5 0.0 7.6e-11 42.3 0.2 2.9 2 1 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.17 KXZ54832.1 - 4.5e-23 81.9 0.0 6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 KXZ54832.1 - 7.6e-23 78.4 0.3 8.9e-06 25.2 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXZ54832.1 - 2.7e-22 77.2 5.7 7.4e-06 25.2 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXZ54832.1 - 0.00011 22.4 0.0 0.00043 20.6 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXZ54832.1 - 0.00024 21.4 0.2 2.5 8.4 0.0 3.3 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 KXZ54832.1 - 0.078 12.3 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KXZ54832.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Acetyltransf_1 PF00583.25 KXZ54833.1 - 8e-12 45.4 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ54833.1 - 3.8e-09 36.5 0.0 5.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXZ54833.1 - 1.9e-08 34.6 0.0 2.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ54833.1 - 9.8e-06 25.5 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXZ54833.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Kelch_4 PF13418.6 KXZ54835.1 - 1.1e-26 92.5 14.5 1.3e-09 37.9 0.0 5.3 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ54835.1 - 8.8e-25 86.1 1.7 5.8e-10 39.1 0.3 4.7 2 2 2 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KXZ54835.1 - 3.5e-23 81.3 10.5 2.8e-06 27.4 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KXZ54835.1 - 2.2e-22 78.3 14.4 2.5e-08 33.4 0.5 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KXZ54835.1 - 2.9e-19 68.2 8.9 5.6e-06 26.1 0.5 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KXZ54835.1 - 8.7e-18 63.9 4.7 1.8e-06 27.8 0.1 5.5 5 0 0 5 5 5 3 Kelch motif fn3 PF00041.21 KXZ54835.1 - 9.1e-08 32.4 0.0 2.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF3450 PF11932.8 KXZ54835.1 - 0.052 12.8 24.8 0.08 12.2 4.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 KXZ54835.1 - 0.23 11.7 16.8 6.6 7.0 4.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Golgin_A5 PF09787.9 KXZ54835.1 - 0.32 10.4 17.4 0.49 9.8 17.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fungal_TACC PF12709.7 KXZ54835.1 - 0.46 10.9 8.6 1.4 9.4 0.0 3.7 3 1 1 4 4 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Atg14 PF10186.9 KXZ54835.1 - 0.64 9.0 13.6 1 8.4 13.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KXZ54835.1 - 0.93 8.8 15.5 1.4 8.2 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KXZ54835.1 - 1.5 8.8 5.2 2.8 8.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KXZ54835.1 - 2.8 8.6 12.4 0.19 12.4 4.5 2.7 1 1 2 3 3 3 0 SlyX UPF0242 PF06785.11 KXZ54835.1 - 2.9 8.0 24.5 34 4.5 24.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4446 PF14584.6 KXZ54835.1 - 4.2 7.4 6.6 20 5.2 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) HrpB7 PF09486.10 KXZ54835.1 - 6.5 7.1 16.9 13 6.1 5.0 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) YabA PF06156.13 KXZ54835.1 - 8.9 7.0 13.3 1.4 9.6 2.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Pex16 PF08610.10 KXZ54836.1 - 3.8e-06 26.3 0.0 1.9e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Pex16 PF08610.10 KXZ54837.1 - 2.3e-23 82.9 0.1 3.4e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Tmemb_14 PF03647.13 KXZ54838.1 - 1.2e-15 58.0 13.7 1.8e-15 57.4 13.7 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C Abhydrolase_6 PF12697.7 KXZ54839.1 - 3e-11 44.3 0.3 2e-07 31.9 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ54839.1 - 0.0014 18.0 0.0 0.0081 15.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ54839.1 - 0.057 13.0 0.0 0.088 12.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FPN1 PF06963.12 KXZ54841.1 - 4.6e-76 256.1 0.6 1e-47 162.8 3.3 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) adh_short PF00106.25 KXZ54842.1 - 5.2e-23 81.5 0.1 7e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ54842.1 - 4.1e-12 46.2 0.0 6.8e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ54842.1 - 7.4e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 KR domain AAA PF00004.29 KXZ54843.1 - 6.8e-11 42.7 0.0 3.9e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KXZ54843.1 - 1.7e-05 24.7 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 KXZ54843.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KXZ54843.1 - 0.0017 18.3 0.1 0.01 15.8 0.1 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 KXZ54843.1 - 0.0029 17.2 0.9 0.071 12.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KXZ54843.1 - 0.0049 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXZ54843.1 - 0.0087 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXZ54843.1 - 0.019 15.2 0.1 0.11 12.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXZ54843.1 - 0.021 15.3 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ54843.1 - 0.04 14.3 0.0 0.04 14.3 0.0 3.1 3 1 0 3 3 2 0 AAA ATPase domain AAA_33 PF13671.6 KXZ54843.1 - 0.07 13.3 0.0 0.07 13.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_assoc_2 PF16193.5 KXZ54843.1 - 0.088 13.2 0.2 0.23 11.8 0.2 1.7 1 0 0 1 1 1 0 AAA C-terminal domain NTPase_1 PF03266.15 KXZ54843.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KXZ54843.1 - 0.26 10.5 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF1754 PF08555.10 KXZ54845.1 - 1.6e-08 35.3 12.7 1.6e-08 35.3 12.7 1.7 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4192 PF13830.6 KXZ54845.1 - 2.6 8.0 4.6 3.3 7.7 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RR_TM4-6 PF06459.12 KXZ54845.1 - 9.4 6.0 11.4 11 5.7 11.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tub PF01167.18 KXZ54846.1 - 6.3e-64 216.0 0.0 8.2e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Tub family TOBE_2 PF08402.10 KXZ54846.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 TOBE domain ETF PF01012.21 KXZ54847.1 - 4.3e-37 127.8 4.2 7.3e-37 127.0 4.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KXZ54847.1 - 4.2e-34 116.4 0.8 1.2e-33 115.0 0.8 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain EGF_CA PF07645.15 KXZ54848.1 - 1.5e-07 31.5 48.3 1.4e-05 25.2 0.3 6.1 6 0 0 6 6 6 5 Calcium-binding EGF domain Ricin_B_lectin PF00652.22 KXZ54849.1 - 2.1e-08 34.5 0.0 6.7e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXZ54849.1 - 3.3e-07 30.9 0.1 9.4e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like PAN_4 PF14295.6 KXZ54849.1 - 6.3e-05 22.8 0.2 0.00021 21.1 0.2 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXZ54849.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 PAN domain Pkinase PF00069.25 KXZ54850.1 - 7.4e-15 55.0 0.0 1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54850.1 - 6e-05 22.4 0.0 0.00056 19.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 KXZ54850.1 - 0.07 12.6 0.4 0.98 9.0 0.0 2.6 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Methyltransf_16 PF10294.9 KXZ54852.1 - 5.4e-15 55.6 0.0 7.5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXZ54852.1 - 0.0067 15.9 0.0 0.0093 15.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXZ54852.1 - 0.24 11.0 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain LRR_8 PF13855.6 KXZ54853.1 - 1.5 8.6 19.7 1.3 8.8 0.4 7.6 7 3 1 8 8 8 0 Leucine rich repeat DEC-1_C PF04626.13 KXZ54853.1 - 5.4 7.4 9.2 2 8.8 2.5 2.4 2 0 0 2 2 2 0 Dec-1 protein, C terminal region Pkinase PF00069.25 KXZ54854.1 - 2.3e-32 112.4 0.0 1.2e-31 110.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54854.1 - 6.8e-31 107.5 0.0 8.7e-24 84.2 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ54854.1 - 1e-05 24.6 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ion_trans PF00520.31 KXZ54856.1 - 2.8e-107 357.5 22.6 4e-56 190.0 5.4 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KXZ54856.1 - 4e-09 35.7 1.9 4e-09 35.7 1.9 4.5 3 2 1 4 4 4 3 Polycystin cation channel GPHH PF16905.5 KXZ54856.1 - 0.00018 21.2 0.0 0.00044 20.0 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ion_trans PF00520.31 KXZ54857.1 - 2.3e-94 315.2 22.8 3.6e-49 167.2 0.8 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KXZ54857.1 - 0.0001 21.1 7.3 0.0001 21.1 7.3 3.9 3 1 1 4 4 4 3 Polycystin cation channel LRR_8 PF13855.6 KXZ54858.1 - 2.3e-05 24.0 3.3 0.46 10.3 0.0 6.8 8 1 0 8 8 8 2 Leucine rich repeat LRR_4 PF12799.7 KXZ54858.1 - 0.00023 21.5 3.3 16 6.1 0.0 7.5 7 1 1 8 8 8 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXZ54858.1 - 0.00054 19.8 10.6 33 4.9 0.0 8.8 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.33 KXZ54858.1 - 0.0019 18.5 0.8 1.1e+02 4.0 0.0 6.4 7 1 0 7 7 7 0 Leucine Rich Repeat Ion_trans PF00520.31 KXZ54859.1 - 1.2e-187 620.7 56.8 1.5e-50 171.7 6.7 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KXZ54859.1 - 1.6e-08 33.7 1.7 1.6e-08 33.7 1.7 7.9 6 3 2 8 8 8 4 Polycystin cation channel GPHH PF16905.5 KXZ54859.1 - 0.00026 20.7 0.0 0.00071 19.3 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF2238 PF09997.9 KXZ54859.1 - 0.51 10.1 5.3 1.5 8.6 0.1 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) Hemerythrin PF01814.23 KXZ54860.1 - 9.7e-11 42.4 2.9 1.6e-10 41.7 2.9 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain TBCA PF02970.16 KXZ54861.1 - 3e-25 88.3 7.9 4e-25 88.0 7.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A RRN3 PF05327.11 KXZ54861.1 - 0.1 11.1 3.7 0.11 11.0 3.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4404 PF14357.6 KXZ54861.1 - 1.6 9.4 6.5 23 5.7 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DBINO PF13892.6 KXZ54861.1 - 1.8 9.0 9.1 0.89 9.9 4.4 2.0 1 1 1 2 2 2 0 DNA-binding domain UCH PF00443.29 KXZ54862.1 - 3.7e-10 39.7 0.0 1.3e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF629 PF04780.12 KXZ54862.1 - 4.6e-05 22.1 0.0 4.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF629) WD40 PF00400.32 KXZ54863.1 - 1e-09 38.9 0.2 1.9e-05 25.3 0.1 4.7 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ54863.1 - 0.026 14.8 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXZ54863.1 - 0.18 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF647 PF04884.14 KXZ54865.1 - 1.2e-65 221.5 3.4 1.2e-65 221.5 3.4 1.6 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis PCI PF01399.27 KXZ54866.1 - 3e-11 43.7 0.0 6.8e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain Histone PF00125.24 KXZ54869.1 - 5.4e-54 182.1 2.1 6e-54 181.9 2.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ54869.1 - 0.00014 22.1 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ54869.1 - 0.00036 20.6 0.1 0.0007 19.7 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KXZ54869.1 - 0.00065 20.3 1.5 0.00079 20.0 1.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KXZ54869.1 - 0.0055 17.0 0.8 0.0089 16.3 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ54869.1 - 0.0094 16.0 0.1 0.017 15.2 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KXZ54870.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ54870.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ54870.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ54870.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ54870.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ54870.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ54870.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated SNF2_N PF00176.23 KXZ54871.1 - 2.2e-48 164.8 0.0 4.9e-48 163.6 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 KXZ54871.1 - 5.1e-23 82.0 0.2 7.4e-15 55.1 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3535) HEAT PF02985.22 KXZ54871.1 - 3.8e-13 48.5 29.5 0.00017 21.5 0.0 9.3 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 KXZ54871.1 - 9e-07 29.3 6.8 0.00023 21.6 0.3 12.6 10 2 3 13 13 13 3 HEAT-like repeat VirB3 PF05101.13 KXZ54872.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DLIC PF05783.11 KXZ54873.1 - 1.3 7.8 3.8 2.5 6.9 3.8 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Actin PF00022.19 KXZ54874.1 - 1.8e-99 333.1 0.0 1e-98 330.6 0.0 1.8 1 1 0 1 1 1 1 Actin AROS PF15684.5 KXZ54875.1 - 0.11 13.1 10.6 0.12 12.9 10.6 1.1 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Tho2 PF11262.8 KXZ54875.1 - 0.33 10.1 6.9 0.38 9.9 6.9 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ABC_tran PF00005.27 KXZ54876.1 - 4.6e-20 72.5 0.0 1.3e-19 71.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ54876.1 - 3e-11 43.7 3.1 2.3e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ54876.1 - 1.7e-07 30.9 0.0 3e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXZ54876.1 - 0.0083 15.8 0.1 0.0083 15.8 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KXZ54876.1 - 0.012 15.4 0.2 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ54876.1 - 0.018 15.3 1.3 0.021 15.1 0.5 1.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXZ54876.1 - 0.02 14.6 0.3 0.038 13.7 0.3 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KXZ54876.1 - 0.022 14.6 0.4 0.04 13.8 0.4 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXZ54876.1 - 0.023 15.1 0.1 0.041 14.3 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXZ54876.1 - 0.024 14.8 0.1 0.82 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXZ54876.1 - 0.053 12.9 0.2 0.074 12.4 0.2 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 KXZ54876.1 - 0.06 13.3 2.3 0.092 12.7 0.3 2.0 2 0 0 2 2 2 0 NACHT domain DLIC PF05783.11 KXZ54876.1 - 0.068 12.0 0.1 0.099 11.5 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_25 PF13481.6 KXZ54876.1 - 0.11 12.0 0.8 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXZ54876.1 - 0.15 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF3987 PF13148.6 KXZ54876.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MobB PF03205.14 KXZ54876.1 - 0.23 11.4 0.2 0.39 10.6 0.2 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 KXZ54876.1 - 0.3 11.6 0.5 0.41 11.1 0.5 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KXZ54876.1 - 0.37 10.4 0.0 0.53 9.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RNase_T PF00929.24 KXZ54878.1 - 0.0066 17.0 0.0 0.0076 16.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Acyl-CoA_dh_M PF02770.19 KXZ54879.1 - 6.6e-16 58.3 0.0 1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXZ54879.1 - 0.00037 21.1 0.1 0.0028 18.3 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 KXZ54879.1 - 0.042 14.4 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Pentapeptide PF00805.22 KXZ54880.1 - 2.1e-12 46.4 4.8 1.3e-05 24.7 1.7 3.3 2 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KXZ54880.1 - 2.8e-06 27.4 0.5 0.0013 18.9 0.0 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KXZ54880.1 - 1.6e-05 25.0 2.2 0.006 16.7 0.4 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) OprD PF03573.13 KXZ54880.1 - 0.004 16.3 0.0 0.0065 15.6 0.1 1.4 1 1 0 1 1 1 1 outer membrane porin, OprD family BAR PF03114.18 KXZ54881.1 - 0.00018 21.3 5.0 0.00054 19.7 5.0 1.8 1 1 0 1 1 1 1 BAR domain Seryl_tRNA_N PF02403.22 KXZ54881.1 - 0.2 11.9 4.5 12 6.2 0.1 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HIP1_clath_bdg PF16515.5 KXZ54881.1 - 0.25 12.0 6.5 0.24 12.0 2.7 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ead_Ea22 PF13935.6 KXZ54881.1 - 1.9 9.1 5.1 2.7 8.7 2.6 2.2 2 1 0 2 2 2 0 Ead/Ea22-like protein K_channel_TID PF07941.11 KXZ54881.1 - 2.7 8.5 12.8 7.7 7.0 12.8 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Na_H_Exchanger PF00999.21 KXZ54882.1 - 8.1e-62 209.2 35.6 1.2e-61 208.6 35.6 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 KXZ54882.1 - 4.8e-20 71.9 0.9 1.1e-19 70.9 0.0 2.1 3 0 0 3 3 3 1 TrkA-N domain eIF-4B PF06273.11 KXZ54883.1 - 5.4e-33 114.8 69.5 3.4e-15 56.1 9.0 4.2 1 1 2 3 3 3 3 Plant specific eukaryotic initiation factor 4B Mito_carr PF00153.27 KXZ54883.1 - 1.5e-28 98.5 1.6 1.2e-14 54.0 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Dynamitin PF04912.14 KXZ54883.1 - 0.43 9.9 3.9 0.65 9.3 3.9 1.2 1 0 0 1 1 1 0 Dynamitin DUF4407 PF14362.6 KXZ54883.1 - 3.9 6.7 10.5 0.19 11.0 4.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cytochrome_CBB3 PF13442.6 KXZ54884.1 - 4.5e-13 49.3 0.2 8.3e-11 42.1 0.2 2.2 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KXZ54884.1 - 1.8e-06 29.0 0.0 3.9e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 KXZ54884.1 - 0.0022 17.7 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Pyr_redox_2 PF07992.14 KXZ54885.1 - 3.8e-38 131.4 0.0 4.8e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ54885.1 - 3.1e-10 40.5 0.9 8.6e-06 26.2 1.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXZ54885.1 - 3.4e-05 24.0 2.4 0.0028 17.8 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXZ54885.1 - 0.00059 19.9 2.0 0.77 9.7 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXZ54885.1 - 0.025 13.9 3.7 1.3 8.2 0.3 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXZ54885.1 - 0.025 13.3 0.3 1 8.0 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KXZ54885.1 - 0.032 13.8 11.7 0.14 11.7 0.0 3.7 2 1 1 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ54885.1 - 0.081 12.0 7.4 0.33 10.0 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KXZ54885.1 - 0.13 11.1 0.4 10 4.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KXZ54885.1 - 0.27 10.2 1.5 7.4 5.5 1.8 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KXZ54885.1 - 0.56 9.2 6.7 0.77 8.8 0.6 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Chloroa_b-bind PF00504.21 KXZ54886.1 - 1.8e-53 181.4 0.1 2.2e-53 181.1 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Dirigent PF03018.14 KXZ54887.1 - 8.4e-06 25.6 0.0 9.3e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Dirigent-like protein Allene_ox_cyc PF06351.11 KXZ54887.1 - 0.00012 21.8 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Allene oxide cyclase AOC_like PF18678.1 KXZ54887.1 - 0.022 14.3 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain TylF PF05711.11 KXZ54888.1 - 6.4e-40 137.1 0.0 8.6e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 KXZ54888.1 - 0.001 20.1 0.0 0.0015 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Nucleotid_trans PF03407.16 KXZ54889.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF3666 PF12408.8 KXZ54889.1 - 0.24 10.6 0.0 0.52 9.6 0.0 1.5 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase ABC_tran PF00005.27 KXZ54890.1 - 1.8e-31 109.4 0.0 3.2e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXZ54890.1 - 7.1e-28 98.0 1.4 1e-27 97.5 1.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KXZ54890.1 - 6.7e-08 32.2 2.0 2.3e-06 27.2 0.1 2.4 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXZ54890.1 - 0.00049 20.5 0.3 0.0024 18.3 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXZ54890.1 - 0.015 15.6 0.1 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KXZ54890.1 - 0.016 15.1 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KXZ54890.1 - 0.02 14.6 1.5 0.046 13.4 0.3 2.2 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KXZ54890.1 - 0.021 13.6 0.3 0.14 10.9 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 KXZ54890.1 - 0.037 13.6 1.4 0.15 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KXZ54890.1 - 0.045 13.5 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXZ54890.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KXZ54890.1 - 0.08 12.2 0.1 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KXZ54890.1 - 0.11 12.6 0.4 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXZ54890.1 - 0.16 12.1 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 KXZ54890.1 - 0.22 12.1 0.2 1.3 9.6 0.3 2.0 1 1 1 2 2 2 0 AAA domain DAO PF01266.24 KXZ54891.1 - 1.9e-20 73.8 1.0 2.1e-20 73.6 1.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Asp_protease_2 PF13650.6 KXZ54893.1 - 1.9e-15 57.2 0.2 3.6e-10 40.3 0.1 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KXZ54893.1 - 4.6e-10 39.9 0.1 2.2e-06 28.2 0.0 2.5 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Methyltransf_12 PF08242.12 KXZ54894.1 - 2.7e-11 44.1 0.0 3.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ54894.1 - 3.3e-11 43.7 0.0 5.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ54894.1 - 3.1e-09 36.9 0.0 4.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ54894.1 - 8.4e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXZ54894.1 - 7.7e-05 22.3 0.0 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KXZ54894.1 - 0.0035 18.3 0.0 0.0057 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXZ54894.1 - 0.012 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.6 KXZ54894.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_6 PF13516.6 KXZ54895.1 - 7e-20 69.3 3.4 7.9e-06 25.5 0.0 5.1 5 0 0 5 5 5 4 Leucine Rich repeat LRR_8 PF13855.6 KXZ54895.1 - 0.00014 21.6 3.6 0.014 15.1 0.6 4.3 3 1 1 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 KXZ54895.1 - 0.00064 20.1 6.5 0.0031 17.9 0.2 3.8 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) ComFB PF10719.9 KXZ54895.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Late competence development protein ComFB ING PF12998.7 KXZ54896.1 - 1.4e-18 67.3 3.4 2e-18 66.8 3.4 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXZ54896.1 - 1.6e-06 27.9 5.9 3e-06 27.0 5.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXZ54896.1 - 0.004 17.4 1.1 0.0083 16.4 1.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain PhoU PF01895.19 KXZ54896.1 - 0.059 13.8 2.5 0.082 13.4 0.8 1.9 1 1 1 2 2 2 0 PhoU domain DUF5376 PF17346.2 KXZ54896.1 - 0.076 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5376) DUF4407 PF14362.6 KXZ54896.1 - 0.36 10.1 2.9 0.52 9.6 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_2 PF13639.6 KXZ54896.1 - 1.2 9.5 6.0 2.3 8.6 6.0 1.5 1 0 0 1 1 1 0 Ring finger domain DUF4404 PF14357.6 KXZ54896.1 - 1.3 9.8 5.0 1.9 9.2 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HK97-gp10_like PF04883.12 KXZ54897.1 - 3.6 8.6 8.1 19 6.3 0.5 2.8 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Ank_3 PF13606.6 KXZ54898.1 - 0.0045 17.4 0.3 0.56 10.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXZ54898.1 - 0.04 14.4 0.1 4.6 7.9 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat DUF1664 PF07889.12 KXZ54900.1 - 4.2e-30 104.3 0.4 7.7e-30 103.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) AIP3 PF03915.13 KXZ54900.1 - 0.039 13.1 1.9 0.055 12.6 1.9 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Nsp1_C PF05064.13 KXZ54900.1 - 0.095 12.5 2.5 0.2 11.5 2.5 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region Snapin_Pallidin PF14712.6 KXZ54900.1 - 0.12 12.8 5.8 0.15 12.5 4.0 1.9 2 0 0 2 2 2 0 Snapin/Pallidin DUF948 PF06103.11 KXZ54900.1 - 0.12 12.6 2.0 0.93 9.8 0.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2443 PF10398.9 KXZ54900.1 - 0.14 12.2 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Fib_alpha PF08702.10 KXZ54900.1 - 0.22 11.7 1.7 0.44 10.7 1.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TLD PF07534.16 KXZ54901.1 - 2.2e-24 86.3 0.0 5.8e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 TLD Pkinase PF00069.25 KXZ54902.1 - 5.4e-55 186.6 0.0 4.7e-30 104.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54902.1 - 3.8e-21 75.5 0.0 1.5e-10 40.8 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KXZ54902.1 - 0.09 13.5 0.1 0.16 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein kinase C terminal domain Ribonuc_L-PSP PF01042.21 KXZ54905.1 - 4.1e-41 139.8 0.2 4.6e-41 139.6 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP zf-MYND PF01753.18 KXZ54906.1 - 2e-07 31.0 10.1 4.2e-07 29.9 10.1 1.6 1 0 0 1 1 1 1 MYND finger OmdA PF13376.6 KXZ54907.1 - 0.16 12.0 1.4 0.25 11.4 0.4 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Cys_Met_Meta_PP PF01053.20 KXZ54908.1 - 3e-135 450.6 0.0 3.8e-135 450.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ldh_2 PF02615.14 KXZ54908.1 - 2.2e-80 270.3 0.2 3.3e-80 269.8 0.2 1.3 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Aminotran_5 PF00266.19 KXZ54908.1 - 4.8e-06 25.8 0.2 1.3e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXZ54908.1 - 0.0081 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXZ54908.1 - 0.021 14.2 0.3 0.04 13.2 0.3 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family LRR_4 PF12799.7 KXZ54909.1 - 0.068 13.6 1.9 6.4 7.3 0.3 3.3 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 KXZ54910.1 - 0.047 14.1 0.5 0.047 14.1 0.5 5.5 5 0 0 5 5 5 0 EGF-like domain I-EGF_1 PF18372.1 KXZ54910.1 - 0.067 13.3 0.3 0.067 13.3 0.3 4.5 3 1 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 EGF_Tenascin PF18720.1 KXZ54910.1 - 3.9 7.6 35.1 0.032 14.3 1.7 4.4 3 0 0 3 3 3 0 Tenascin EGF domain Smac_DIABLO PF09057.10 KXZ54911.1 - 0.43 9.9 4.7 1.1 8.6 0.4 2.1 1 1 1 2 2 2 0 Second Mitochondria-derived Activator of Caspases Filament PF00038.21 KXZ54912.1 - 0.023 14.3 49.3 0.037 13.6 20.7 3.1 1 1 2 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KXZ54912.1 - 0.085 12.9 23.7 0.19 11.8 0.2 4.2 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Asp_protease_2 PF13650.6 KXZ54912.1 - 0.14 12.8 0.1 0.47 11.1 0.1 2.0 1 0 0 1 1 1 0 Aspartyl protease RICH PF05062.12 KXZ54912.1 - 2.1 8.7 8.8 3.4 8.1 0.4 3.7 2 2 1 3 3 3 0 RICH domain Sds3 PF08598.11 KXZ54912.1 - 2.6 8.0 29.5 2.9 7.8 4.7 3.3 1 1 1 2 2 2 0 Sds3-like Apolipoprotein PF01442.18 KXZ54912.1 - 7.3 6.4 80.6 5.3 6.9 32.3 2.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Tropomyosin_1 PF12718.7 KXZ54913.1 - 0.66 10.1 12.2 0.14 12.3 4.1 2.3 1 1 0 2 2 2 0 Tropomyosin like Filament PF00038.21 KXZ54913.1 - 0.93 9.0 16.2 0.39 10.3 5.2 2.5 1 1 1 2 2 2 0 Intermediate filament protein DUF2730 PF10805.8 KXZ54913.1 - 1 9.5 4.4 1.9 8.6 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TMF_DNA_bd PF12329.8 KXZ54913.1 - 2.2 8.3 8.4 1 9.4 2.4 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 KXZ54913.1 - 2.4 7.9 13.1 4.5 7.1 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PSI_PsaF PF02507.15 KXZ54914.1 - 0.17 11.7 0.3 0.84 9.5 0.0 2.3 3 0 0 3 3 3 0 Photosystem I reaction centre subunit III PSP PF04046.16 KXZ54914.1 - 0.25 11.2 1.4 23 4.9 0.1 2.5 2 0 0 2 2 2 0 PSP Ysc84 PF04366.12 KXZ54915.1 - 7.7e-28 96.8 0.1 2.1e-27 95.4 0.1 1.8 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 KXZ54915.1 - 1.2e-16 60.5 9.2 2.1e-16 59.8 9.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KXZ54915.1 - 0.7 10.1 8.0 1.1 9.5 8.0 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_2 PF14445.6 KXZ54915.1 - 6.5 7.0 8.9 0.98 9.6 3.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 zf-MYND PF01753.18 KXZ54916.1 - 2.8e-08 33.7 8.8 5.5e-08 32.8 8.8 1.5 1 0 0 1 1 1 1 MYND finger zf-RING_2 PF13639.6 KXZ54917.1 - 5.5e-12 45.8 8.8 8.8e-12 45.2 8.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXZ54917.1 - 5.6e-11 42.3 7.2 1e-10 41.4 7.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXZ54917.1 - 1.7e-10 40.6 5.8 2.8e-10 39.9 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ54917.1 - 2.4e-10 40.1 9.3 4.1e-10 39.3 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ54917.1 - 9.4e-10 38.2 7.7 1.4e-09 37.6 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXZ54917.1 - 4.2e-09 36.6 4.2 7.5e-09 35.8 4.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXZ54917.1 - 2.7e-08 33.8 9.0 5.2e-08 32.9 9.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXZ54917.1 - 4e-08 33.1 5.5 6.9e-08 32.3 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXZ54917.1 - 3.1e-06 26.9 8.0 6.3e-05 22.8 8.8 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXZ54917.1 - 2.5e-05 24.2 3.6 4.8e-05 23.3 3.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KXZ54917.1 - 0.00078 19.2 3.3 0.0013 18.5 3.3 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KXZ54917.1 - 0.021 14.5 3.9 0.044 13.4 3.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 KXZ54917.1 - 0.034 14.0 4.7 0.077 12.9 4.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 KXZ54917.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 U-box domain zinc-ribbons_6 PF07191.12 KXZ54917.1 - 0.22 11.5 5.9 0.36 10.8 5.9 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 KXZ54917.1 - 0.27 11.1 7.5 0.24 11.2 3.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KXZ54917.1 - 0.38 10.8 7.5 3 7.9 7.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C2HC5 PF06221.13 KXZ54917.1 - 0.49 10.4 4.9 5.6 7.0 5.1 2.4 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type TerY_C PF15616.6 KXZ54917.1 - 0.51 10.5 5.6 0.85 9.7 5.6 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_10 PF16685.5 KXZ54917.1 - 0.75 10.0 5.4 1.3 9.2 5.4 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KXZ54917.1 - 0.92 9.7 10.4 1.5 9.1 0.3 2.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-MIZ PF02891.20 KXZ54917.1 - 1.9 8.3 6.3 4.1 7.2 6.3 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PP2C_2 PF13672.6 KXZ54918.1 - 0.043 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C Methyltransf_16 PF10294.9 KXZ54919.1 - 1.8e-22 79.9 0.0 2.7e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KXZ54919.1 - 0.00016 22.3 0.0 0.0014 19.3 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ54919.1 - 0.00031 20.6 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ54919.1 - 0.02 15.6 0.0 0.052 14.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ54919.1 - 0.11 13.1 0.0 0.71 10.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KXZ54919.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ank_2 PF12796.7 KXZ54920.1 - 3.5e-28 98.0 1.8 2.9e-08 34.2 0.0 5.1 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ54920.1 - 1.1e-18 67.3 12.6 2.1e-06 28.2 0.0 7.5 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ54920.1 - 2.9e-11 42.5 13.2 0.33 11.7 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 KXZ54920.1 - 6.2e-10 39.1 22.9 0.051 14.0 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KXZ54920.1 - 2.1e-06 27.9 11.2 0.052 13.9 0.1 6.5 2 1 5 7 7 7 2 Ankyrin repeats (many copies) STAS_2 PF13466.6 KXZ54923.1 - 0.0044 17.3 10.4 0.015 15.6 0.1 4.6 3 0 0 3 3 3 2 STAS domain Peptidase_M14 PF00246.24 KXZ54924.1 - 3.2e-19 69.8 0.0 1.1e-18 68.0 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase FeoC PF09012.10 KXZ54925.1 - 0.033 14.3 0.8 8 6.6 0.0 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator Acid_PPase PF12689.7 KXZ54925.1 - 0.051 13.4 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 Acid Phosphatase FAM183 PF14886.6 KXZ54926.1 - 0.0028 18.4 0.0 0.0041 17.8 0.0 1.4 1 0 0 1 1 1 1 FAM183A and FAM183B related PsaM PF07465.13 KXZ54927.1 - 0.096 12.4 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Fe_hyd_lg_C PF02906.14 KXZ54929.1 - 1.1e-95 320.0 0.0 1.9e-95 319.2 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KXZ54929.1 - 1.1e-25 89.5 0.8 2.1e-25 88.5 0.8 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Transglut_core PF01841.19 KXZ54930.1 - 1.9e-10 41.2 0.9 8.5e-10 39.1 0.9 2.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KXZ54930.1 - 2.1e-10 40.5 2.4 3.7e-10 39.7 2.4 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain FAD_binding_3 PF01494.19 KXZ54930.1 - 0.0011 18.3 0.2 0.1 11.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain PAW PF04721.17 KXZ54930.1 - 0.0049 16.7 0.2 0.0073 16.1 0.2 1.2 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.10 KXZ54930.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 PUB domain SR-25 PF10500.9 KXZ54931.1 - 0.0058 16.3 9.5 0.0058 16.3 9.5 4.6 4 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein Coilin_N PF15862.5 KXZ54931.1 - 3.2 7.6 17.9 36 4.1 0.0 4.5 3 2 1 4 4 4 0 Coilin N-terminus Lactamase_B_2 PF12706.7 KXZ54932.1 - 0.00011 21.8 1.1 0.00035 20.2 0.9 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.12 KXZ54932.1 - 0.00028 20.7 0.0 0.00057 19.8 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain DRMBL PF07522.14 KXZ54932.1 - 0.00031 20.9 0.0 0.0011 19.1 0.0 1.8 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Peptidase_U32 PF01136.19 KXZ54933.1 - 7.1e-86 287.1 0.0 3.6e-74 248.8 0.0 2.5 2 0 0 2 2 2 2 Peptidase family U32 DUF3656 PF12392.8 KXZ54933.1 - 2.5e-15 57.0 0.0 4.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Collagenase Rgp1 PF08737.10 KXZ54933.1 - 5.6e-11 42.3 0.0 3.8e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 Rgp1 Integrin_B_tail PF07965.12 KXZ54933.1 - 0.65 10.5 1.6 1.4 9.4 0.4 1.9 2 0 0 2 2 2 0 Integrin beta tail domain PAD_porph PF04371.15 KXZ54934.1 - 2.9e-98 329.1 0.0 3.8e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase RTC PF01137.21 KXZ54935.1 - 1.8e-66 223.6 0.1 2.1e-66 223.3 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KXZ54935.1 - 3.3e-19 69.3 0.3 6.6e-19 68.3 0.3 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain AAA_34 PF13872.6 KXZ54936.1 - 3.1e-103 344.8 0.0 3.6e-102 341.3 0.0 2.2 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 KXZ54936.1 - 1.2e-96 323.6 0.0 3.2e-94 315.6 0.0 2.4 1 1 0 1 1 1 1 C-terminal domain on Strawberry notch homologue E2F_TDP PF02319.20 KXZ54938.1 - 9.2e-23 80.1 0.3 1.7e-22 79.3 0.3 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 KXZ54938.1 - 1.6e-20 73.2 0.0 2.4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain TrmB PF01978.19 KXZ54938.1 - 0.00082 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_47 PF16221.5 KXZ54938.1 - 0.058 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 winged helix-turn-helix B-block_TFIIIC PF04182.12 KXZ54938.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC DUF2250 PF10007.9 KXZ54938.1 - 0.16 12.1 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Thioredoxin PF00085.20 KXZ54939.1 - 2.8e-28 97.9 0.0 3.3e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ54939.1 - 2e-08 34.6 0.1 4.5e-08 33.5 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ54939.1 - 1.7e-07 31.5 0.0 1.4e-05 25.3 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KXZ54939.1 - 3.9e-06 26.9 0.0 6.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KXZ54939.1 - 0.00045 20.2 0.0 0.00066 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 KXZ54939.1 - 0.0032 17.2 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KXZ54939.1 - 0.0033 17.2 0.2 0.012 15.4 0.1 1.7 1 1 1 2 2 2 1 Redoxin DSBA PF01323.20 KXZ54939.1 - 0.018 14.8 0.0 0.12 12.1 0.0 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain KaiB PF07689.12 KXZ54939.1 - 0.055 13.2 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 KaiB domain PI3_PI4_kinase PF00454.27 KXZ54940.1 - 1.7e-42 146.0 0.0 3.3e-42 145.0 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KXZ54940.1 - 2.7e-14 52.7 0.3 5.2e-14 51.8 0.3 1.5 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KXZ54940.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 FAT domain RRP7 PF12923.7 KXZ54941.1 - 9.3e-30 103.2 4.4 1.4e-29 102.6 4.4 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 KXZ54941.1 - 9.2e-08 31.8 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_min_cap2 PF06152.11 KXZ54941.1 - 0.0018 17.3 0.2 0.0027 16.7 0.2 1.2 1 0 0 1 1 1 1 Phage minor capsid protein 2 RRM_7 PF16367.5 KXZ54941.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_Rrp7 PF17799.1 KXZ54941.1 - 0.045 13.5 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain HA2 PF04408.23 KXZ54942.1 - 0.0031 17.8 0.0 0.0058 16.9 0.0 1.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) AF-4 PF05110.13 KXZ54942.1 - 0.26 9.3 3.9 0.33 9.0 3.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Helicase_C PF00271.31 KXZ54943.1 - 8.8e-10 38.9 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ54943.1 - 2.3e-06 27.5 0.1 5.4e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 KXZ54943.1 - 1e-05 25.7 0.1 2.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_19 PF13245.6 KXZ54943.1 - 0.0065 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KXZ54943.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 KXZ54943.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXZ54943.1 - 0.14 12.5 1.9 0.52 10.7 1.9 2.0 1 1 0 1 1 1 0 AAA ATPase domain Exo_endo_phos PF03372.23 KXZ54943.1 - 0.15 11.6 0.5 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family AAA_22 PF13401.6 KXZ54943.1 - 0.17 12.2 0.3 0.5 10.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain PsbQ PF05757.11 KXZ54944.1 - 7.9e-05 22.5 2.0 9.1e-05 22.3 2.0 1.1 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) YtxH PF12732.7 KXZ54944.1 - 1.5 9.4 5.8 0.63 10.6 1.0 2.1 2 0 0 2 2 2 0 YtxH-like protein BLOC1S3 PF15753.5 KXZ54945.1 - 0.11 12.6 6.8 0.13 12.4 6.8 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ER_lumen_recept PF00810.18 KXZ54946.1 - 3.5e-54 183.6 12.5 3.5e-54 183.6 12.5 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor 2_5_RNA_ligase2 PF13563.6 KXZ54947.1 - 2.1e-22 79.7 0.1 5.3e-22 78.4 0.1 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Peptidase_C27 PF05407.12 KXZ54947.1 - 0.04 14.0 0.5 0.074 13.1 0.5 1.4 1 0 0 1 1 1 0 Rubella virus endopeptidase EF-hand_1 PF00036.32 KXZ54948.1 - 3.2e-18 63.9 5.3 1.6e-06 27.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ54948.1 - 1.1e-17 64.2 2.9 1.9e-10 41.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ54948.1 - 5.1e-16 57.2 3.6 9.1e-08 31.5 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXZ54948.1 - 3.2e-14 52.5 3.0 1.1e-08 34.8 0.2 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ54948.1 - 2.7e-06 26.6 4.4 0.0019 17.6 0.1 4.4 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 KXZ54948.1 - 5.7e-06 26.6 0.1 6.1e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain Peptidase_M43 PF05572.13 KXZ54950.1 - 6e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXZ54950.1 - 0.0092 16.2 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 KXZ54950.1 - 0.058 13.0 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 KXZ54950.1 - 0.067 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like fn2 PF00040.19 KXZ54950.1 - 0.31 11.4 5.6 5.8 7.3 0.2 2.7 2 0 0 2 2 2 0 Fibronectin type II domain Histone PF00125.24 KXZ54952.1 - 5.5e-22 78.5 4.2 6.7e-22 78.3 4.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ54952.1 - 0.00011 22.4 0.0 0.00034 20.8 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KXZ54952.1 - 0.0025 17.9 1.5 0.004 17.2 1.5 1.4 1 1 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 KXZ54952.1 - 0.003 18.0 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ54952.1 - 0.035 13.8 0.2 0.52 9.9 0.1 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF3391 PF11871.8 KXZ54952.1 - 1.5 9.3 8.1 3.7 8.1 8.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Histone_H2A_C PF16211.5 KXZ54953.1 - 3.8e-19 68.1 2.2 7.2e-19 67.2 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ54953.1 - 8e-17 61.8 0.0 9.9e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ54953.1 - 4.9e-05 23.5 0.0 7.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YGGT PF02325.17 KXZ54954.1 - 1.4e-13 51.0 3.2 2e-13 50.5 3.2 1.2 1 0 0 1 1 1 1 YGGT family Hydrolase_3 PF08282.12 KXZ54955.1 - 1e-09 38.5 0.0 5e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXZ54955.1 - 8.9e-08 32.0 0.0 2.6e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 KXZ54955.1 - 0.0053 15.9 0.0 0.015 14.4 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase SPEG_u2 PF16650.5 KXZ54956.1 - 0.16 12.2 1.5 3.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein Gly-zipper_OmpA PF13436.6 KXZ54958.1 - 0.012 15.3 13.1 0.47 10.3 13.1 2.4 1 1 0 1 1 1 0 Glycine-zipper domain Bacteriocin_IIc PF10439.9 KXZ54958.1 - 0.26 11.4 12.1 5.9 7.1 12.1 2.3 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Ribosomal_L27A PF00828.19 KXZ54962.1 - 4.9e-30 104.8 0.0 9.2e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TAF4 PF05236.14 KXZ54964.1 - 5.1e-07 29.7 4.6 5.1e-07 29.7 4.6 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family TAF4 PF05236.14 KXZ54965.1 - 0.0002 21.2 0.1 0.0002 21.2 0.1 2.8 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Sporozoite_P67 PF05642.11 KXZ54965.1 - 0.083 11.0 1.2 0.19 9.8 1.2 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Aminotran_1_2 PF00155.21 KXZ54966.1 - 7.9e-28 97.7 0.0 3.3e-16 59.4 0.0 2.8 1 1 1 2 2 2 2 Aminotransferase class I and II Ribosomal_L18p PF00861.22 KXZ54967.1 - 1.6e-46 157.4 2.5 2e-46 157.1 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ubiq_cyt_C_chap PF03981.12 KXZ54968.1 - 7.5e-16 58.5 0.1 7.5e-16 58.5 0.1 2.2 2 1 1 3 3 3 1 Ubiquinol-cytochrome C chaperone cobW PF02492.19 KXZ54969.1 - 8.4e-53 178.6 0.0 1.4e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ54969.1 - 5e-19 68.0 0.0 9.6e-19 67.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KXZ54969.1 - 0.0037 16.8 0.1 0.45 10.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXZ54969.1 - 0.0045 16.9 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXZ54969.1 - 0.014 15.6 0.0 0.046 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXZ54969.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KXZ54969.1 - 0.021 15.2 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXZ54969.1 - 0.024 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXZ54969.1 - 0.044 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 KXZ54969.1 - 0.05 12.6 0.9 0.94 8.4 0.1 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KXZ54969.1 - 0.088 13.4 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TAXi_C PF14541.6 KXZ54970.1 - 1.8e-21 76.6 0.0 3.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 KXZ54970.1 - 4.3e-15 55.9 0.0 5.9e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXZ54970.1 - 5.2e-13 49.6 0.0 1e-12 48.7 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Rieske PF00355.26 KXZ54971.1 - 1.1e-12 47.8 0.0 2.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KXZ54971.1 - 2.1e-08 34.5 0.0 4.6e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Filament_head PF04732.14 KXZ54972.1 - 0.31 11.9 5.0 0.49 11.3 5.0 1.3 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region AMP-binding PF00501.28 KXZ54973.1 - 5.2e-88 295.5 0.0 6.3e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ54973.1 - 1.2e-23 83.8 0.2 2.7e-23 82.7 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXZ54973.1 - 1.3e-20 73.1 3.4 2.8e-20 72.0 3.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus MatE PF01554.18 KXZ54974.1 - 2.3e-35 121.6 22.7 9.5e-18 64.4 6.2 2.8 2 1 1 3 3 3 2 MatE BTB PF00651.31 KXZ54976.1 - 0.001 19.3 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain bZIP_2 PF07716.15 KXZ54977.1 - 2.6e-07 30.6 7.0 5.7e-07 29.5 7.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXZ54977.1 - 0.00012 22.1 9.4 0.00012 22.1 9.4 1.6 2 0 0 2 2 2 1 bZIP transcription factor EF-hand_7 PF13499.6 KXZ54978.1 - 4.4e-15 55.9 0.0 1.3e-10 41.5 0.3 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ54978.1 - 2.2e-14 51.9 0.5 3.7e-05 23.0 0.3 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KXZ54978.1 - 3e-14 51.6 0.3 0.003 17.3 0.1 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KXZ54978.1 - 2.8e-11 43.1 0.0 2.3e-07 30.5 0.0 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KXZ54978.1 - 3.9e-08 32.4 3.3 0.00039 19.8 0.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 KXZ54978.1 - 0.002 19.0 0.0 0.013 16.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 KXZ54978.1 - 0.0089 15.9 0.0 0.067 13.1 0.0 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 KXZ54978.1 - 0.011 16.0 0.0 0.043 14.1 0.0 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SKIP_SNW PF02731.15 KXZ54979.1 - 1e-70 236.5 0.6 1e-70 236.5 0.6 2.2 2 0 0 2 2 2 1 SKIP/SNW domain FOP_dimer PF09398.10 KXZ54979.1 - 0.019 15.2 0.2 0.039 14.2 0.2 1.4 1 0 0 1 1 1 0 FOP N terminal dimerisation domain MSG PF02349.15 KXZ54980.1 - 0.0024 18.0 0.1 0.0024 18.0 0.1 2.6 3 0 0 3 3 3 1 Major surface glycoprotein Lebercilin PF15619.6 KXZ54980.1 - 0.0029 17.3 27.2 0.0029 17.3 27.2 5.4 2 2 3 5 5 5 3 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 KXZ54980.1 - 0.0046 17.2 20.1 0.0046 17.2 20.1 5.5 2 2 3 5 5 5 2 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KXZ54980.1 - 0.0057 16.7 42.6 0.15 12.1 4.1 6.6 2 2 4 6 6 6 3 Protein of unknown function (DUF1664) CENP-H PF05837.12 KXZ54980.1 - 0.013 15.9 3.5 0.013 15.9 3.5 8.4 3 3 6 9 9 9 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 KXZ54980.1 - 0.018 15.2 1.6 0.018 15.2 1.6 8.1 2 2 6 8 8 8 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 KXZ54980.1 - 3.2 7.3 96.1 0.12 12.0 15.8 5.6 2 2 2 4 4 4 0 Intermediate filament protein Sec34 PF04136.15 KXZ54980.1 - 7.8 6.4 33.2 0.045 13.6 2.2 5.6 2 2 0 5 5 5 0 Sec34-like family cNMP_binding PF00027.29 KXZ54981.1 - 0.00032 20.7 0.0 0.11 12.6 0.0 3.5 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain DUF1751 PF08551.10 KXZ54982.1 - 3 8.5 5.3 3.4 8.3 0.4 2.9 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Metallophos PF00149.28 KXZ54983.1 - 7.1e-36 124.6 0.1 1.8e-34 120.0 0.1 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Kelch_3 PF13415.6 KXZ54983.1 - 3.2e-15 56.0 14.2 3.7e-05 23.9 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ54983.1 - 4.3e-13 48.9 1.1 0.056 13.5 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KXZ54983.1 - 9.1e-12 44.8 8.3 0.0058 16.6 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ54983.1 - 2.4e-07 30.8 9.0 0.058 13.7 0.2 6.1 5 2 2 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KXZ54983.1 - 6.2e-06 26.0 4.6 0.14 12.2 0.3 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KXZ54983.1 - 0.00076 19.0 10.6 0.58 9.8 0.0 5.9 6 1 0 6 6 6 1 Kelch motif STPPase_N PF16891.5 KXZ54983.1 - 0.0027 18.1 0.0 0.0048 17.3 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain GNAT_acetyltran PF12746.7 KXZ54983.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Ank_2 PF12796.7 KXZ54984.1 - 0.00019 22.0 0.2 0.00056 20.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ54984.1 - 0.002 18.5 0.6 0.94 10.3 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat FAD_binding_3 PF01494.19 KXZ54985.1 - 4.4e-14 52.5 0.6 4.4e-06 26.2 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXZ54985.1 - 4.8e-05 22.7 0.1 0.00019 20.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ54985.1 - 0.00013 21.7 1.2 0.03 13.9 0.6 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KXZ54985.1 - 0.00019 20.7 0.4 0.0003 20.0 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXZ54985.1 - 0.00096 18.0 0.1 0.0015 17.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KXZ54985.1 - 0.001 18.6 0.2 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXZ54985.1 - 0.0027 16.6 1.1 0.84 8.4 0.0 2.5 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KXZ54985.1 - 0.0053 17.0 0.1 0.015 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXZ54985.1 - 0.0071 15.6 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXZ54985.1 - 0.0074 16.8 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXZ54985.1 - 0.018 14.1 0.5 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXZ54985.1 - 0.026 14.5 1.6 1.4 8.9 0.1 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding MiaE_2 PF13794.6 KXZ54985.1 - 0.12 12.1 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Methyltransf_25 PF13649.6 KXZ54986.1 - 2e-12 47.6 0.3 8.4e-12 45.6 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXZ54986.1 - 1.8e-10 40.7 0.1 2.5e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXZ54986.1 - 1e-08 35.7 0.1 5e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXZ54986.1 - 1.4e-07 31.2 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KXZ54986.1 - 2.8e-07 30.4 0.0 5.7e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXZ54986.1 - 1.7e-06 29.0 0.8 5e-06 27.5 0.2 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ54986.1 - 6.4e-06 26.8 0.0 1.4e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ54986.1 - 9e-06 25.6 0.0 2.3e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXZ54986.1 - 5.8e-05 22.5 0.0 8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KXZ54986.1 - 0.00025 21.0 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXZ54986.1 - 0.0024 17.9 1.5 0.0048 16.9 1.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 KXZ54986.1 - 0.0028 17.7 0.0 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 KXZ54986.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 KXZ54986.1 - 0.026 14.3 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KXZ54986.1 - 0.096 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_9 PF08003.11 KXZ54986.1 - 0.22 10.4 0.0 0.38 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pkinase PF00069.25 KXZ54987.1 - 2.1e-24 86.3 0.0 5.3e-24 85.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54987.1 - 3.8e-13 49.3 0.0 5.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TTRAP PF14203.6 KXZ54987.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein MT-A70 PF05063.14 KXZ54988.1 - 4.6e-41 140.6 0.0 6.3e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 MT-A70 Elong-fact-P_C PF09285.11 KXZ54989.1 - 1.8e-27 94.8 3.2 3.3e-27 94.0 0.4 2.3 1 1 1 2 2 2 1 Elongation factor P, C-terminal EFP PF01132.20 KXZ54989.1 - 0.00051 20.0 0.1 0.0039 17.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Pkinase PF00069.25 KXZ54990.1 - 1.5e-26 93.4 0.0 3.9e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54990.1 - 6.6e-17 61.6 0.0 9e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TTRAP PF14203.6 KXZ54990.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein FYDLN_acid PF09538.10 KXZ54991.1 - 0.3 11.8 3.5 0.54 11.0 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) MT-A70 PF05063.14 KXZ54992.1 - 2.4e-15 56.9 0.1 3.4e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 MT-A70 MT-A70 PF05063.14 KXZ54993.1 - 1.4e-12 47.8 0.1 5.8e-12 45.9 0.1 1.8 1 1 0 1 1 1 1 MT-A70 DUF1317 PF07026.11 KXZ54993.1 - 0.0027 17.5 0.1 0.0054 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1317) Pkinase PF00069.25 KXZ54994.1 - 2.4e-18 66.4 0.0 9.2e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ54994.1 - 1.6e-06 27.6 0.0 2.3e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2281 PF10047.9 KXZ54994.1 - 0.17 12.6 0.0 0.29 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) SBP PF03110.14 KXZ54995.1 - 1e-24 86.6 7.2 1.4e-24 86.2 7.2 1.2 1 0 0 1 1 1 1 SBP domain PHD PF00628.29 KXZ54996.1 - 1.8e-12 47.0 3.1 2.7e-12 46.4 3.1 1.3 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 KXZ54996.1 - 0.056 13.8 0.2 0.056 13.8 0.2 1.6 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 KXZ54996.1 - 0.11 12.1 2.8 0.28 10.8 2.8 1.7 1 0 0 1 1 1 0 PHD-finger DZR PF12773.7 KXZ54996.1 - 0.59 10.2 4.5 3.9 7.6 4.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 KXZ54996.1 - 1.8 8.6 8.2 0.089 12.7 1.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KXZ54996.1 - 2.9 8.3 5.5 5.4 7.4 5.5 1.4 1 0 0 1 1 1 0 Ring finger domain Prim_Zn_Ribbon PF08273.12 KXZ54996.1 - 6.8 7.1 7.2 36 4.7 0.0 3.2 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-ribbon_3 PF13248.6 KXZ54996.1 - 7.4 6.1 8.2 15 5.2 3.1 2.5 2 1 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.18 KXZ54996.1 - 7.6 6.0 9.4 0.28 10.6 0.7 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others rve PF00665.26 KXZ54997.1 - 3.6e-09 36.9 0.0 5.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KXZ54997.1 - 0.00017 21.7 0.1 0.00098 19.2 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 KXZ54997.1 - 0.033 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain MT-A70 PF05063.14 KXZ54999.1 - 2.4e-17 63.4 0.0 3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 MT-A70 EFP_N PF08207.12 KXZ55000.1 - 1.8e-27 95.2 0.3 1.2e-26 92.4 0.1 2.4 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 KXZ55000.1 - 6.1e-27 93.1 1.9 1.6e-26 91.8 0.5 2.5 1 1 1 2 2 2 1 Elongation factor P, C-terminal EFP PF01132.20 KXZ55000.1 - 2.8e-18 65.7 0.9 9.4e-18 64.0 0.6 2.0 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Oxidored_FMN PF00724.20 KXZ55004.1 - 3.8e-71 240.1 0.0 1.2e-70 238.4 0.0 1.6 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KXZ55004.1 - 0.024 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 KXZ55004.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Orn_Arg_deC_N PF02784.16 KXZ55005.1 - 3.4e-50 170.7 0.0 4.3e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXZ55005.1 - 1.3e-25 89.4 0.0 1.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 KXZ55005.1 - 4.1e-10 39.7 0.0 9.5e-10 38.5 0.0 1.6 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain RNA_pol_I_A49 PF06870.12 KXZ55006.1 - 1.1e-29 103.6 0.0 2.4e-29 102.4 0.0 1.5 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Ank_2 PF12796.7 KXZ55008.1 - 4.5e-08 33.6 0.1 7.9e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ55008.1 - 7.1e-08 32.6 0.1 2.1e-07 31.1 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ55008.1 - 2.7e-05 24.6 0.0 0.00039 20.9 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_24 PF13578.6 KXZ55008.1 - 0.0024 18.9 0.0 0.0062 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ank PF00023.30 KXZ55008.1 - 0.0063 16.9 0.1 0.055 13.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXZ55008.1 - 0.029 14.9 0.0 0.52 11.1 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Methyltransf_25 PF13649.6 KXZ55008.1 - 0.032 14.9 0.0 0.057 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2781 PF10914.8 KXZ55009.1 - 1e-44 152.5 8.0 1.1e-44 152.4 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Rhomboid PF01694.22 KXZ55011.1 - 1.8e-11 44.2 9.2 2.4e-11 43.8 9.2 1.2 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 KXZ55011.1 - 0.028 14.4 0.9 0.035 14.1 0.9 1.2 1 0 0 1 1 1 0 Der1-like family Tim17 PF02466.19 KXZ55012.1 - 3.3e-13 50.0 1.5 3.3e-13 50.0 1.5 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family TTL PF03133.15 KXZ55013.1 - 2e-47 161.8 0.0 1.3e-31 109.8 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXZ55013.1 - 0.00026 20.3 0.0 0.033 13.4 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KXZ55013.1 - 0.029 13.6 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp PPR_2 PF13041.6 KXZ55014.1 - 4.5e-34 116.4 0.0 9.1e-07 29.0 0.0 9.3 5 3 4 9 9 9 8 PPR repeat family PPR PF01535.20 KXZ55014.1 - 8.8e-31 104.0 4.2 0.00081 19.5 0.0 11.2 12 0 0 12 12 12 5 PPR repeat PPR_1 PF12854.7 KXZ55014.1 - 1.6e-25 88.5 0.0 3.2e-05 23.5 0.0 9.4 11 0 0 11 11 11 5 PPR repeat PPR_3 PF13812.6 KXZ55014.1 - 3.7e-25 87.8 0.0 2.2e-10 40.5 0.0 5.4 4 2 1 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KXZ55014.1 - 1.3e-15 57.4 0.0 2.8e-06 26.9 0.2 4.3 2 2 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_12 PF13424.6 KXZ55014.1 - 0.019 15.2 19.9 0.038 14.3 0.1 5.6 3 2 1 5 5 5 0 Tetratricopeptide repeat PrmC_N PF17827.1 KXZ55014.1 - 0.07 13.7 0.3 0.07 13.7 0.3 3.5 4 0 0 4 4 4 0 PrmC N-terminal domain TPR_4 PF07721.14 KXZ55014.1 - 0.083 13.6 37.4 1.2 10.0 0.2 9.8 8 0 0 8 8 8 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 KXZ55015.1 - 3.7e-28 98.7 2.8 7.7e-28 97.6 2.8 1.5 1 0 0 1 1 1 1 Subtilase family zf-HIT PF04438.16 KXZ55016.1 - 1.9e-07 30.8 8.3 2.9e-07 30.2 8.3 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 KXZ55016.1 - 0.37 11.0 5.6 0.59 10.3 5.6 1.2 1 0 0 1 1 1 0 B-box zinc finger Peptidase_M50 PF02163.22 KXZ55018.1 - 0.0078 15.5 1.3 2.4 7.4 0.1 2.3 2 0 0 2 2 2 2 Peptidase family M50 DUF4604 PF15377.6 KXZ55018.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) COX2 PF00116.20 KXZ55021.1 - 3.4e-46 156.0 0.0 4.3e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Foamy_virus_ENV PF03408.14 KXZ55022.1 - 0.17 9.7 0.2 0.23 9.3 0.2 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein Ank_2 PF12796.7 KXZ55023.1 - 5.5e-52 174.3 36.0 1.2e-14 54.7 2.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ55023.1 - 5.9e-29 96.9 8.2 0.0074 16.7 0.0 9.0 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 KXZ55023.1 - 4.2e-25 87.8 11.0 2.7e-08 34.2 0.4 7.2 2 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ55023.1 - 7.3e-22 77.2 24.5 5.7e-06 26.5 1.5 8.0 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KXZ55023.1 - 4.4e-21 74.3 25.1 6e-05 23.3 0.5 10.1 10 1 1 11 11 11 6 Ankyrin repeat HET PF06985.11 KXZ55023.1 - 0.00087 19.7 0.0 0.00087 19.7 0.0 3.0 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KXZ55024.1 - 2e-35 121.2 14.0 1.2e-15 57.8 0.2 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ55024.1 - 4.9e-27 93.6 17.0 2.4e-09 37.3 1.1 6.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXZ55024.1 - 2.3e-26 91.8 2.8 1.4e-10 41.5 0.1 6.2 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55024.1 - 4e-26 88.2 5.5 0.0001 22.5 0.1 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 KXZ55024.1 - 1.6e-21 75.7 14.6 7.5e-06 26.2 0.1 8.1 8 1 1 9 9 9 5 Ankyrin repeat HET PF06985.11 KXZ55024.1 - 0.00081 19.8 0.0 0.00081 19.8 0.0 2.9 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AtpR PF12966.7 KXZ55025.1 - 0.09 13.2 3.1 0.49 10.9 3.1 2.0 1 1 0 1 1 1 0 N-ATPase, AtpR subunit DUF5364 PF17322.2 KXZ55025.1 - 0.13 12.6 1.6 0.56 10.5 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5364) Herpes_DNAp_acc PF04929.12 KXZ55025.1 - 0.62 9.0 2.7 0.87 8.5 2.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Kinesin PF00225.23 KXZ55026.1 - 2.1e-20 72.9 0.0 1.1e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KXZ55026.1 - 0.0047 16.9 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding Ank_2 PF12796.7 KXZ55027.1 - 2.3e-09 37.7 0.0 0.0032 18.0 0.0 5.1 3 3 3 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ55027.1 - 3.6e-08 33.8 4.8 5.8 7.6 0.0 7.1 5 3 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55027.1 - 3.2e-06 27.1 10.2 52 4.9 0.0 10.3 10 2 2 12 12 12 0 Ankyrin repeat Ank_5 PF13857.6 KXZ55027.1 - 0.0057 16.9 7.9 8.5 6.8 0.1 6.0 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ55027.1 - 0.13 12.7 0.0 50 4.6 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeat KGG PF10685.9 KXZ55027.1 - 2.7 8.4 12.2 0.3 11.4 2.3 3.0 3 0 0 3 3 3 0 Stress-induced bacterial acidophilic repeat motif PEMT PF04191.13 KXZ55030.1 - 1.8e-09 37.9 1.2 1.8e-09 37.9 1.2 2.4 2 1 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 KXZ55030.1 - 5e-06 26.8 0.1 1.2e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KXZ55030.1 - 0.014 14.9 0.2 0.083 12.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1295) Pterin_4a PF01329.19 KXZ55031.1 - 9.5e-15 54.6 0.0 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DinB PF05163.12 KXZ55032.1 - 0.028 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 DinB family C2 PF00168.30 KXZ55033.1 - 0.00011 22.4 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain DivIC PF04977.15 KXZ55033.1 - 0.05 13.4 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Med19 PF10278.9 KXZ55034.1 - 1.4 8.8 3.0 2.3 8.1 3.0 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2956 PF11169.8 KXZ55034.1 - 9 6.5 6.5 16 5.8 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF746 PF05344.11 KXZ55035.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DUF2232 PF09991.9 KXZ55035.1 - 0.096 11.8 0.3 0.1 11.7 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Chlorosome_CsmC PF11098.8 KXZ55035.1 - 0.12 12.3 0.1 0.38 10.7 0.0 1.7 1 1 1 2 2 2 0 Chlorosome envelope protein C YgaB PF14182.6 KXZ55035.1 - 0.14 12.6 1.6 0.2 12.1 1.6 1.3 1 1 0 1 1 1 0 YgaB-like protein Cohesin_load PF10345.9 KXZ55035.1 - 0.16 10.4 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Cohesin loading factor Bromodomain PF00439.25 KXZ55036.1 - 1.3e-14 54.1 0.1 2.3e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain OMPdecase PF00215.24 KXZ55037.1 - 3e-78 262.5 0.0 5.1e-78 261.7 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 KXZ55037.1 - 2.2e-11 43.5 0.1 4.9e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ARID PF01388.21 KXZ55038.1 - 5.5e-07 30.2 0.0 8.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Acetyltransf_7 PF13508.7 KXZ55041.1 - 4.1e-10 39.9 0.0 7.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ55041.1 - 1.1e-09 38.5 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXZ55041.1 - 9e-07 28.9 0.0 3.6e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXZ55041.1 - 3.1e-06 27.0 0.1 1e-05 25.4 0.1 1.8 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KXZ55041.1 - 0.00067 19.7 0.0 0.0014 18.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXZ55041.1 - 0.066 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ PPR_2 PF13041.6 KXZ55042.1 - 9.6e-15 54.5 0.0 7.6e-06 26.0 0.0 3.3 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.6 KXZ55042.1 - 1.7e-12 47.2 0.0 0.00047 20.2 0.0 2.6 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 KXZ55042.1 - 1.5e-08 34.3 0.0 0.0034 17.5 0.0 4.2 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 KXZ55042.1 - 6.6e-08 32.1 1.4 0.0011 18.6 0.0 5.1 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 KXZ55042.1 - 3.7e-06 26.5 0.0 2.4e-05 23.8 0.0 1.9 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TIR_2 PF13676.6 KXZ55044.1 - 1.4e-20 74.0 0.3 3.4e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 TIR domain Arm PF00514.23 KXZ55044.1 - 6.5e-10 38.7 10.7 0.0015 18.5 0.1 7.2 6 1 0 6 6 6 3 Armadillo/beta-catenin-like repeat SAM_2 PF07647.17 KXZ55044.1 - 1.2e-08 35.0 0.0 3.8e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXZ55044.1 - 5.3e-08 33.2 0.3 3.3e-07 30.7 0.3 2.3 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) TIR PF01582.20 KXZ55044.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain DUF5578 PF17741.1 KXZ55044.1 - 0.03 13.7 0.1 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5578) HEAT_2 PF13646.6 KXZ55044.1 - 0.26 11.7 7.1 33 5.0 0.0 4.1 3 1 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 KXZ55044.1 - 0.44 11.1 8.2 20 5.8 0.0 4.1 3 1 0 3 3 3 0 HEAT-like repeat DFP PF04127.15 KXZ55045.1 - 0.00018 21.4 0.1 0.0029 17.4 0.0 2.2 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein Fez1 PF06818.15 KXZ55046.1 - 2 8.9 25.5 4.6 7.6 0.4 4.1 3 1 0 3 3 3 0 Fez1 CCDC84 PF14968.6 KXZ55046.1 - 4.5 6.8 7.7 0.61 9.6 2.3 2.2 3 0 0 3 3 3 0 Coiled coil protein 84 Ras PF00071.22 KXZ55047.1 - 1.3e-31 109.4 0.0 1.5e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ55047.1 - 4.8e-15 55.8 0.0 6.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ55047.1 - 0.00023 20.7 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXZ55047.1 - 0.00052 19.6 0.0 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXZ55047.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 KXZ55047.1 - 0.0077 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Septin PF00735.18 KXZ55047.1 - 0.034 13.4 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Septin GBP PF02263.19 KXZ55047.1 - 0.058 12.6 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Thymopoietin PF08198.11 KXZ55047.1 - 0.12 12.0 0.1 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 Thymopoietin protein WD40 PF00400.32 KXZ55049.1 - 2.8e-09 37.4 12.2 1.4e-05 25.7 0.0 3.9 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55049.1 - 3.5e-05 24.0 0.0 0.0096 16.2 0.0 2.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-MYND PF01753.18 KXZ55050.1 - 1.6e-09 37.7 3.4 1.6e-09 37.7 3.4 1.9 2 0 0 2 2 2 1 MYND finger VATC PF18716.1 KXZ55050.1 - 8 6.4 10.1 0.83 9.6 1.1 2.7 2 1 0 2 2 2 0 Vms1-associating treble clef domain tRNA-synt_1e PF01406.19 KXZ55051.1 - 2.1e-110 368.8 0.0 7.6e-97 324.3 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KXZ55051.1 - 1.8e-08 33.6 0.0 1.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KXZ55051.1 - 0.00028 21.3 0.0 0.00079 19.8 0.0 1.7 1 0 0 1 1 1 1 DALR domain CAP_N PF01213.19 KXZ55051.1 - 0.01 15.3 1.1 0.017 14.7 1.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1631 PF07793.11 KXZ55051.1 - 2.1 6.7 7.8 2.9 6.2 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) AAA_12 PF13087.6 KXZ55052.1 - 3.6e-40 137.7 0.0 5.6e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ55052.1 - 1.8e-18 67.3 0.0 4.5e-09 36.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KXZ55052.1 - 8.8e-06 25.6 0.1 1.9 8.2 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KXZ55052.1 - 4.8e-05 23.7 0.0 0.00077 19.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXZ55052.1 - 0.00052 19.8 0.4 0.0014 18.4 0.3 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_29 PF13555.6 KXZ55052.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ55052.1 - 0.028 14.8 0.5 0.13 12.7 0.6 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KXZ55052.1 - 0.33 11.4 0.0 0.33 11.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 KXZ55052.1 - 0.33 10.9 11.2 0.57 10.1 11.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAS-6_N PF16531.5 KXZ55053.1 - 2e-28 98.8 1.2 2.9e-28 98.3 1.2 1.2 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Cellulase PF00150.18 KXZ55054.1 - 2e-08 34.0 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Dzip-like_N PF13815.6 KXZ55055.1 - 3.7e-28 97.9 2.9 3.7e-28 97.9 2.9 7.2 8 0 0 8 8 8 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C4H2 PF10146.9 KXZ55055.1 - 0.0022 18.3 0.1 0.0022 18.3 0.1 5.2 3 2 0 4 4 4 1 Zinc finger-containing protein Bacillus_HBL PF05791.11 KXZ55055.1 - 0.36 10.6 14.9 2.9 7.7 0.0 4.8 4 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) HAUS2 PF15003.6 KXZ55055.1 - 2 8.1 9.8 0.31 10.7 0.4 3.3 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 2 CRIC_ras_sig PF10534.9 KXZ55055.1 - 4.6 7.5 6.8 4.5 7.5 0.6 4.1 3 1 1 4 4 4 0 Connector enhancer of kinase suppressor of ras NIR_SIR_ferr PF03460.17 KXZ55056.1 - 0.14 12.0 0.1 0.43 10.5 0.1 1.8 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain Homeodomain PF00046.29 KXZ55056.1 - 0.42 10.5 5.2 1.7 8.5 0.2 3.0 3 0 0 3 3 3 0 Homeodomain Metal_resist PF13801.6 KXZ55057.1 - 0.002 18.3 2.1 0.002 18.3 2.1 3.3 4 1 0 4 4 4 1 Heavy-metal resistance bZIP_2 PF07716.15 KXZ55057.1 - 0.015 15.3 0.7 0.04 14.0 0.7 1.7 1 0 0 1 1 1 0 Basic region leucine zipper TSC22 PF01166.18 KXZ55057.1 - 0.048 14.0 0.2 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family KASH_CCD PF14662.6 KXZ55057.1 - 0.096 12.5 4.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KXZ55057.1 - 0.24 11.5 1.0 0.59 10.3 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF1825 PF08855.10 KXZ55057.1 - 0.26 11.2 2.5 0.17 11.8 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) HALZ PF02183.18 KXZ55057.1 - 0.3 11.4 0.9 0.56 10.5 0.1 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper TolA_bind_tri PF16331.5 KXZ55057.1 - 1.9 8.6 8.9 0.43 10.7 0.7 3.0 2 1 1 3 3 3 0 TolA binding protein trimerisation Pkinase PF00069.25 KXZ55059.1 - 1.2e-48 165.8 0.0 1.4e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55059.1 - 4.7e-15 55.6 0.0 6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ55059.1 - 0.002 17.5 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXZ55059.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family NHase_alpha PF02979.16 KXZ55059.1 - 0.13 11.5 0.6 0.29 10.4 0.5 1.5 1 1 1 2 2 2 0 Nitrile hydratase, alpha chain SNase PF00565.17 KXZ55060.1 - 5e-13 49.5 0.0 7.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue CBF PF03914.17 KXZ55062.1 - 3.4e-34 118.3 0.0 5.3e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 CBF/Mak21 family Acetyltransf_6 PF13480.7 KXZ55062.1 - 0.57 10.3 5.1 1.3 9.1 0.8 3.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KXZ55063.1 - 1.2e-11 45.1 0.0 0.00039 20.9 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ55063.1 - 3.5e-08 33.1 2.7 13 6.8 0.1 8.2 10 0 0 10 10 10 3 Ankyrin repeat Ank_4 PF13637.6 KXZ55063.1 - 4e-07 30.4 4.6 0.01 16.4 0.0 5.8 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ55063.1 - 6.8e-05 23.1 10.8 2.2 8.7 0.0 7.0 7 2 2 9 9 9 3 Ankyrin repeats (many copies) EF-hand_6 PF13405.6 KXZ55064.1 - 1.5e-12 46.4 3.4 0.0075 16.1 0.1 5.9 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 KXZ55064.1 - 7.6e-10 37.6 2.4 0.18 11.5 0.1 5.2 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 KXZ55064.1 - 5.3e-08 33.2 4.7 0.0015 18.9 0.2 4.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_13 PF17958.1 KXZ55064.1 - 0.0086 15.9 0.1 0.12 12.1 0.0 2.7 2 2 2 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 KXZ55064.1 - 0.049 13.2 0.7 12 5.6 0.0 3.8 4 0 0 4 4 4 0 EF hand DUF2778 PF10908.8 KXZ55064.1 - 0.11 12.8 0.8 0.41 11.0 0.0 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF2778) Aminotran_1_2 PF00155.21 KXZ55065.1 - 2.4e-12 46.7 0.0 2.7e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXZ55065.1 - 0.00036 19.6 0.0 0.00041 19.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXZ55065.1 - 0.0036 15.9 0.0 0.0041 15.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase_fungal PF17667.1 KXZ55066.1 - 0.0002 20.3 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KXZ55066.1 - 0.00046 19.6 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXZ55066.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_holin_3_6 PF07332.11 KXZ55066.1 - 0.15 12.1 1.4 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Aminotran_1_2 PF00155.21 KXZ55067.1 - 3.2e-20 72.6 0.0 3.1e-17 62.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXZ55067.1 - 0.007 15.4 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Glutaredoxin PF00462.24 KXZ55070.1 - 3.6e-15 55.9 0.0 2.4e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 KXZ55070.1 - 0.081 13.3 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Ribosomal_L18A PF01775.17 KXZ55071.1 - 2.5e-53 179.3 2.1 3.2e-53 178.9 2.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Pro_isomerase PF00160.21 KXZ55072.1 - 3e-26 92.6 0.0 3.4e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD R3H PF01424.22 KXZ55073.1 - 4.7e-09 36.1 0.0 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 KXZ55073.1 - 0.0012 19.6 1.0 0.0012 19.6 1.0 3.4 4 1 0 4 4 4 1 SUZ domain TFIIA PF03153.13 KXZ55073.1 - 2 8.3 17.1 3.9 7.4 17.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_1 PF00515.28 KXZ55074.1 - 1.1e-07 31.3 0.1 0.0043 16.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ55074.1 - 2.6e-07 30.3 0.8 0.27 11.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ55074.1 - 0.00032 21.3 10.8 0.002 18.8 1.8 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ55074.1 - 0.00042 19.9 2.6 2.9 7.7 0.1 3.4 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 KXZ55074.1 - 0.0013 19.2 9.4 0.31 11.6 0.4 3.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ55074.1 - 0.0014 19.2 2.6 0.49 11.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ55074.1 - 0.0016 18.7 0.2 2.4 8.7 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ55074.1 - 0.016 16.0 8.6 0.74 10.8 0.2 3.7 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ55074.1 - 0.035 14.3 3.4 0.044 13.9 1.4 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KXZ55074.1 - 0.044 14.2 7.7 0.12 12.8 3.4 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 KXZ55074.1 - 0.054 13.8 2.1 0.8 10.0 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 KXZ55074.1 - 0.075 11.4 0.1 0.099 11.0 0.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal OTU PF02338.19 KXZ55075.1 - 2.6e-13 50.6 0.0 3.5e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXZ55075.1 - 6.8e-07 29.0 0.0 0.0012 18.3 0.0 2.3 2 1 0 2 2 2 2 Peptidase C65 Otubain LRR_8 PF13855.6 KXZ55076.1 - 7.6e-25 86.5 43.0 1.4e-08 34.4 0.5 9.1 7 4 3 10 10 10 6 Leucine rich repeat LRR_4 PF12799.7 KXZ55076.1 - 4.7e-21 74.5 27.6 0.00037 20.8 0.3 10.6 8 4 3 12 12 12 7 Leucine Rich repeats (2 copies) DUF4571 PF15137.6 KXZ55076.1 - 0.12 12.0 0.2 11 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4571) LRR_1 PF00560.33 KXZ55076.1 - 0.69 10.7 36.7 13 6.8 0.4 10.8 12 2 0 12 12 12 0 Leucine Rich Repeat Ras PF00071.22 KXZ55077.1 - 6e-58 195.0 0.2 8.1e-58 194.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ55077.1 - 2.4e-37 127.8 0.1 4.3e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ55077.1 - 9.2e-15 54.5 0.2 1.3e-14 54.0 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXZ55077.1 - 1.8e-06 27.5 0.2 2.3e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXZ55077.1 - 2.8e-06 26.8 0.2 4e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXZ55077.1 - 3.4e-06 26.7 0.1 1.4e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXZ55077.1 - 8.4e-05 22.5 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KXZ55077.1 - 0.00012 22.2 0.1 0.00027 21.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ55077.1 - 0.00086 18.9 0.2 0.015 14.8 0.1 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 KXZ55077.1 - 0.03 13.7 0.1 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KXZ55077.1 - 0.034 13.7 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 KXZ55077.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain adh_short_C2 PF13561.6 KXZ55078.1 - 4.5e-41 140.9 0.0 4.1e-40 137.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ55078.1 - 4.9e-26 91.4 0.0 3e-24 85.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXZ55078.1 - 0.0048 16.4 0.0 0.0088 15.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LRR_6 PF13516.6 KXZ55079.1 - 5.6e-09 35.3 6.7 0.016 15.2 0.0 7.9 10 0 0 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.7 KXZ55079.1 - 1.4e-07 31.7 0.0 2.6 8.6 0.1 5.7 4 1 1 6 6 6 3 Leucine Rich repeats (2 copies) DUF2358 PF10184.9 KXZ55080.1 - 0.00058 20.1 0.0 0.0058 16.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) DUF773 PF05600.12 KXZ55081.1 - 4.1e-125 418.4 0.0 5.8e-125 417.9 0.0 1.2 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF1640 PF07798.11 KXZ55082.1 - 0.0038 17.3 0.1 0.0061 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Tup_N PF08581.10 KXZ55082.1 - 0.0081 16.4 1.8 0.032 14.5 0.3 2.3 1 1 1 2 2 2 1 Tup N-terminal DUF641 PF04859.12 KXZ55082.1 - 0.015 15.7 1.1 0.025 14.9 1.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HAP1_N PF04849.13 KXZ55082.1 - 0.053 12.7 2.7 0.072 12.3 2.7 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 KXZ55082.1 - 0.056 12.8 5.2 0.084 12.2 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 KXZ55082.1 - 0.062 13.4 1.3 0.1 12.7 1.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 KXZ55082.1 - 0.063 13.1 3.6 0.11 12.3 3.4 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4763 PF15960.5 KXZ55082.1 - 0.067 12.5 0.2 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) OmpH PF03938.14 KXZ55082.1 - 0.096 13.0 3.8 0.14 12.5 3.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 KXZ55082.1 - 0.099 12.9 8.4 0.044 14.0 5.6 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain BRE1 PF08647.11 KXZ55082.1 - 0.11 12.6 2.3 0.19 11.8 2.0 1.5 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 KXZ55082.1 - 0.12 12.1 6.2 0.064 13.0 1.3 2.5 1 1 1 2 2 2 0 Septum formation initiator GAS PF13851.6 KXZ55082.1 - 0.14 11.5 3.0 0.22 10.9 3.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HAUS-augmin3 PF14932.6 KXZ55082.1 - 0.14 11.7 3.5 0.19 11.3 3.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 KXZ55082.1 - 0.3 11.1 2.8 1.4 9.0 2.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 KXZ55082.1 - 0.33 11.2 3.3 0.46 10.7 2.4 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5320 PF17253.2 KXZ55082.1 - 0.37 11.9 0.1 0.37 11.9 0.1 3.0 3 1 0 3 3 1 0 Family of unknown function (DUF5320) FUSC PF04632.12 KXZ55082.1 - 0.42 9.1 7.7 0.53 8.8 7.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 KXZ55082.1 - 0.55 10.3 5.3 0.64 10.0 4.4 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KXZ55082.1 - 0.91 8.3 6.0 1.7 7.4 5.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Ead_Ea22 PF13935.6 KXZ55082.1 - 0.94 10.1 6.3 1.5 9.5 1.0 2.2 2 0 0 2 2 2 0 Ead/Ea22-like protein TPR_MLP1_2 PF07926.12 KXZ55082.1 - 1.9 8.6 8.6 14 5.7 1.0 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KXZ55082.1 - 4.1 7.8 7.1 1.9 8.9 2.8 1.9 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 KXZ55082.1 - 6.1 7.4 9.8 14 6.3 9.2 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region SNF2_N PF00176.23 KXZ55083.1 - 2.1e-60 204.3 0.0 2e-48 164.9 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ55083.1 - 2.6e-21 76.1 0.0 1.1e-20 74.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ55083.1 - 1.9e-08 34.5 0.0 5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXZ55083.1 - 9.1e-08 31.6 0.0 2.3e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KXZ55083.1 - 3.7e-07 30.1 0.0 1.2e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Glyco_trans_1_2 PF13524.6 KXZ55083.1 - 0.021 15.2 0.0 0.25 11.8 0.0 2.8 3 0 0 3 3 3 0 Glycosyl transferases group 1 ERCC3_RAD25_C PF16203.5 KXZ55083.1 - 0.04 13.1 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF1840 PF08895.11 KXZ55083.1 - 0.053 13.9 1.6 0.13 12.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PPR_2 PF13041.6 KXZ55084.1 - 5.5e-22 77.7 0.0 5.3e-06 26.5 0.0 5.2 5 1 1 6 6 6 4 PPR repeat family PPR PF01535.20 KXZ55084.1 - 7.1e-16 57.3 6.0 0.0028 17.8 0.0 7.1 7 1 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 KXZ55084.1 - 9.6e-15 54.4 0.0 0.0025 17.9 0.0 3.5 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXZ55084.1 - 7.1e-10 38.4 0.0 0.014 15.1 0.0 4.6 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 KXZ55084.1 - 6.3e-09 35.5 0.3 0.004 16.6 0.1 3.4 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP UTP15_C PF09384.10 KXZ55084.1 - 0.039 13.6 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 UTP15 C terminal FtsJ PF01728.19 KXZ55087.1 - 9.1e-08 32.4 0.1 1.9e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KXZ55087.1 - 0.0073 17.3 1.3 0.054 14.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ55087.1 - 0.01 16.6 0.9 0.051 14.3 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain DUF4692 PF15763.5 KXZ55088.1 - 1.3 9.4 4.9 5.1 7.6 0.4 3.0 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) Pkinase PF00069.25 KXZ55089.1 - 8e-20 71.3 0.0 9.9e-08 31.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55089.1 - 3.8e-09 36.2 0.0 6.9e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Peptidase_M24 PF00557.24 KXZ55090.1 - 1.5e-56 191.4 0.0 2.1e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXZ55090.1 - 1.5e-23 82.9 0.0 2.4e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF4603 PF15376.6 KXZ55091.1 - 0.68 7.2 3.8 0.83 7.0 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) ERGIC_N PF13850.6 KXZ55092.1 - 4.4e-26 91.0 0.1 1e-25 89.9 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 KXZ55092.1 - 2.9e-25 89.4 0.0 4.9e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 KXZ55092.1 - 3.2e-21 75.2 0.0 6.3e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXZ55092.1 - 0.00024 20.5 1.0 0.0011 18.5 0.0 2.3 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXZ55092.1 - 0.015 15.8 0.1 0.041 14.3 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Baculo_PP31 PF05311.11 KXZ55092.1 - 0.068 12.7 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RPAP1_N PF08621.10 KXZ55094.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.7 2 1 0 2 2 2 0 RPAP1-like, N-terminal Chloroa_b-bind PF00504.21 KXZ55095.1 - 6.6e-52 176.3 0.0 8.3e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4495 PF14906.6 KXZ55097.1 - 0.00062 18.9 0.0 0.00097 18.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4495) SNF2_N PF00176.23 KXZ55098.1 - 1.7e-56 191.5 15.8 1.7e-56 191.5 15.8 2.5 2 1 1 3 3 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ55098.1 - 9.4e-18 64.6 0.0 9.4e-18 64.6 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 KXZ55098.1 - 1.4e-06 28.4 8.9 2.6e-06 27.5 8.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXZ55098.1 - 2.1e-06 27.7 4.2 4.4e-06 26.6 4.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXZ55098.1 - 1.1e-05 25.2 6.6 1.9e-05 24.4 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXZ55098.1 - 0.00011 22.0 5.8 0.00024 20.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ55098.1 - 0.00035 20.4 8.3 0.00079 19.2 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ55098.1 - 0.0026 17.7 7.3 0.0054 16.7 7.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXZ55098.1 - 0.0027 18.0 7.9 0.005 17.1 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXZ55098.1 - 0.013 15.4 8.3 0.024 14.5 8.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SpoIIP PF07454.11 KXZ55098.1 - 0.022 14.2 0.7 0.043 13.3 0.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 KXZ55098.1 - 0.096 12.8 5.5 0.21 11.8 5.5 1.6 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 KXZ55098.1 - 0.22 10.3 9.6 0.066 12.0 6.9 1.4 2 0 0 2 2 2 0 Presenilin zf-RING_6 PF14835.6 KXZ55098.1 - 0.44 10.5 4.5 1.1 9.2 4.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TMEM51 PF15345.6 KXZ55098.1 - 0.58 10.0 11.0 1.3 8.8 11.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 RNase_H2_suC PF08615.11 KXZ55098.1 - 0.61 10.3 7.4 0.54 10.4 4.7 2.0 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PAT1 PF09770.9 KXZ55098.1 - 0.84 7.8 31.4 1.3 7.2 31.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 KXZ55098.1 - 4.6 7.2 8.2 12 5.9 8.2 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 KXZ55098.1 - 6 5.7 16.8 9.6 5.1 16.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 KXZ55098.1 - 8.5 5.3 5.3 14 4.6 5.3 1.3 1 0 0 1 1 1 0 CLN3 protein Pkinase PF00069.25 KXZ55099.1 - 2.3e-38 132.1 0.0 3.1e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55099.1 - 4.1e-13 49.2 0.0 5.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ55099.1 - 0.0078 16.2 6.4 0.17 11.8 0.0 3.0 3 1 1 4 4 4 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ55100.1 - 5.9e-31 107.8 0.0 1e-27 97.2 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55100.1 - 6.5e-26 91.2 0.0 5.1e-22 78.4 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ55100.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ55100.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Phage_antitermQ PF06530.12 KXZ55100.1 - 0.21 11.5 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q Kdo PF06293.14 KXZ55100.1 - 0.21 10.9 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MBOAT PF03062.19 KXZ55102.1 - 2.4e-25 89.6 7.8 5.8e-25 88.4 7.8 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PH PF00169.29 KXZ55102.1 - 5.2e-07 30.1 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 PH domain MBOAT_2 PF13813.6 KXZ55102.1 - 0.016 15.5 4.5 0.041 14.2 4.5 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family DUF3584 PF12128.8 KXZ55102.1 - 0.06 10.9 0.3 0.083 10.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4404 PF14357.6 KXZ55102.1 - 0.081 13.6 0.7 0.21 12.3 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) CCDC92 PF14916.6 KXZ55102.1 - 0.15 11.9 1.2 0.31 10.8 1.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Csm1_N PF18504.1 KXZ55102.1 - 0.37 11.2 1.7 29 5.1 0.0 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain DnaJ_CXXCXGXG PF00684.19 KXZ55103.1 - 1.1e-05 25.7 17.1 3e-05 24.3 17.2 1.7 1 1 0 1 1 1 1 DnaJ central domain DUF5351 PF17302.2 KXZ55103.1 - 0.00065 19.8 19.6 0.39 11.0 2.7 4.1 3 1 0 3 3 3 3 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 KXZ55103.1 - 0.0037 17.2 4.6 0.0037 17.2 4.6 3.1 1 1 2 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_9 PF13901.6 KXZ55103.1 - 4.7 7.1 12.7 0.19 11.7 0.8 2.0 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon PfkB PF00294.24 KXZ55104.1 - 7.8e-46 156.8 1.9 1.4e-27 96.8 0.0 2.5 2 1 0 2 2 2 2 pfkB family carbohydrate kinase SRCR PF00530.18 KXZ55105.1 - 2.3e-27 95.4 0.2 6.1e-25 87.6 0.0 2.1 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ55105.1 - 0.00074 20.0 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Thioredoxin PF00085.20 KXZ55106.1 - 8.7e-26 89.9 0.0 1.2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ55106.1 - 1.7e-06 28.5 0.0 2.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KXZ55106.1 - 0.0018 18.1 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KXZ55106.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXZ55106.1 - 0.002 18.4 0.0 0.038 14.3 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KXZ55106.1 - 0.0026 17.7 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ55106.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Redoxin SRCR PF00530.18 KXZ55107.1 - 3.1e-31 107.8 0.1 4.7e-16 59.1 0.1 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ55107.1 - 2.4e-11 44.0 0.7 9.2e-05 22.9 0.4 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KXZ55107.1 - 0.00027 21.4 0.1 0.25 11.9 0.1 2.2 2 0 0 2 2 2 2 Hepsin, SRCR domain Ank_4 PF13637.6 KXZ55108.1 - 1.1e-06 29.1 4.2 0.034 14.7 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ55108.1 - 4.9e-06 27.0 0.4 0.0046 17.5 0.0 3.2 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) F-box PF00646.33 KXZ55108.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain Ank_5 PF13857.6 KXZ55108.1 - 0.0035 17.6 1.1 12 6.4 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55108.1 - 0.018 15.5 1.9 2e+02 3.1 0.1 4.8 5 0 0 5 5 5 0 Ankyrin repeat Exonuc_VIII PF06630.11 KXZ55109.1 - 0.027 14.3 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII FeS_assembly_P PF01883.19 KXZ55111.1 - 1.2e-15 57.4 0.0 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ParA PF10609.9 KXZ55112.1 - 7.5e-33 114.0 0.3 9.6e-33 113.6 0.3 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 KXZ55112.1 - 2e-07 31.5 0.0 3.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) BTB PF00651.31 KXZ55113.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain EspB_PE PF18625.1 KXZ55113.1 - 0.02 15.4 0.3 0.054 14.0 0.3 1.7 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain PPDK_N PF01326.19 KXZ55114.1 - 1.1e-56 192.5 0.0 1.6e-33 116.4 0.0 3.0 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain TPT PF03151.16 KXZ55115.1 - 4.5e-90 301.9 19.4 5.6e-90 301.6 19.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ55115.1 - 5.6e-09 36.3 25.8 2.1e-06 28.0 9.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family Phage_holin_2_4 PF16082.5 KXZ55115.1 - 0.053 13.2 1.0 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF2627 PF11118.8 KXZ55115.1 - 0.13 12.9 1.8 0.67 10.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) tRNA_bind PF01588.20 KXZ55116.1 - 4.1e-34 116.6 0.0 6.1e-34 116.0 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Peptidase_S10 PF00450.22 KXZ55116.1 - 7e-07 29.0 0.0 9.7e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Ter PF05472.11 KXZ55118.1 - 0.015 14.4 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) LRR_6 PF13516.6 KXZ55119.1 - 2.2e-22 77.1 13.7 2.5e-05 24.0 0.1 7.7 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 KXZ55119.1 - 1.3e-05 25.1 0.8 3.3 8.6 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 KXZ55119.1 - 0.0043 17.4 14.1 0.039 14.4 3.3 5.6 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ55119.1 - 0.014 15.2 13.7 0.057 13.2 3.8 5.6 4 1 0 5 5 5 0 Leucine rich repeat ACDC PF14733.6 KXZ55119.1 - 0.023 15.0 0.0 0.069 13.5 0.0 1.9 1 1 0 1 1 1 0 AP2-coincident C-terminal CAP PF00188.26 KXZ55123.1 - 4.7e-18 66.2 7.3 4.7e-18 66.2 7.3 2.0 2 1 0 2 2 2 1 Cysteine-rich secretory protein family TFIIA PF03153.13 KXZ55123.1 - 0.0052 16.8 23.8 0.006 16.6 23.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4728 PF15860.5 KXZ55124.1 - 0.11 13.2 2.8 0.11 13.2 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4728) Rieske PF00355.26 KXZ55126.1 - 4.8e-18 64.9 0.1 9.8e-18 63.9 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ55126.1 - 8.8e-15 54.6 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase MCPVI PF02993.14 KXZ55126.1 - 0.00021 21.2 2.3 0.00037 20.4 2.3 1.3 1 0 0 1 1 1 1 Minor capsid protein VI DUF3136 PF11334.8 KXZ55126.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) COG2 PF06148.11 KXZ55126.1 - 0.15 12.1 5.5 0.14 12.3 3.9 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 KXZ55126.1 - 0.15 11.1 6.1 0.25 10.4 6.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KXZ55126.1 - 0.19 12.2 15.6 0.42 11.1 15.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KXZ55126.1 - 0.4 10.7 13.1 0.84 9.7 13.1 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 KXZ55126.1 - 0.76 10.0 2.8 1.4 9.1 2.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 KXZ55126.1 - 0.86 9.2 5.1 1.4 8.5 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ADIP PF11559.8 KXZ55126.1 - 3.9 7.5 12.7 0.21 11.6 7.2 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CorA PF01544.18 KXZ55126.1 - 4.9 6.4 5.0 2.6 7.3 2.1 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein zf-C3HC4_3 PF13920.6 KXZ55127.1 - 1.8e-07 30.9 8.8 3.2e-07 30.1 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ55127.1 - 1.8e-05 24.5 10.1 3.6e-05 23.5 10.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HATPase_c_3 PF13589.6 KXZ55127.1 - 0.00025 20.9 0.0 0.39 10.5 0.0 2.8 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-RING_5 PF14634.6 KXZ55127.1 - 0.004 17.1 11.8 0.0069 16.3 11.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXZ55127.1 - 0.028 14.8 10.4 0.053 13.9 10.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ55127.1 - 0.039 13.8 10.4 0.069 13.0 10.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ55127.1 - 0.5 10.3 9.6 0.86 9.5 9.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TolA_bind_tri PF16331.5 KXZ55127.1 - 2.7 8.1 6.9 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation zf-P11 PF03854.14 KXZ55127.1 - 2.9 7.6 6.8 6.8 6.4 6.8 1.7 1 0 0 1 1 1 0 P-11 zinc finger K_trans PF02705.16 KXZ55129.1 - 1.6e-136 456.0 29.5 1e-115 387.3 23.2 2.8 1 1 1 2 2 2 2 K+ potassium transporter PBP_like_2 PF12849.7 KXZ55130.1 - 3.1e-45 155.0 9.3 3.7e-35 122.0 0.1 2.6 3 0 0 3 3 3 2 PBP superfamily domain TRP PF06011.12 KXZ55131.1 - 0.0028 16.4 5.1 0.0028 16.4 5.1 2.0 1 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel SARS_X4 PF08779.10 KXZ55131.1 - 0.048 13.9 1.8 0.12 12.6 1.8 1.6 1 0 0 1 1 1 0 SARS coronavirus X4 like Laminin_EGF PF00053.24 KXZ55131.1 - 0.1 12.7 4.3 0.21 11.7 4.3 1.5 1 0 0 1 1 1 0 Laminin EGF domain Ephrin_rec_like PF07699.13 KXZ55131.1 - 0.3 10.9 5.4 1.8 8.4 0.9 2.5 2 0 0 2 2 2 0 Putative ephrin-receptor like TAT_signal PF10518.9 KXZ55132.1 - 0.052 13.4 6.2 0.11 12.3 6.2 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Rhomboid PF01694.22 KXZ55133.1 - 3.6e-10 40.0 14.4 3.6e-10 40.0 14.4 2.1 2 0 0 2 2 2 1 Rhomboid family Pkinase_Tyr PF07714.17 KXZ55134.1 - 2.5e-27 95.8 0.0 8.2e-11 41.7 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ55134.1 - 4.5e-23 82.0 0.0 2.3e-09 37.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain SMP_LBD PF17047.5 KXZ55135.1 - 8.7e-10 38.4 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KXZ55135.1 - 3.4e-06 27.3 0.0 0.004 17.4 0.0 3.0 3 0 0 3 3 3 2 C2 domain SMP_LBD PF17047.5 KXZ55136.1 - 2.2e-12 46.8 0.0 3.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KXZ55136.1 - 0.023 15.0 0.0 0.099 12.9 0.0 2.1 2 0 0 2 2 2 0 C2 domain Spectrin PF00435.21 KXZ55136.1 - 0.078 13.5 2.4 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Spectrin repeat Cu_amine_oxidN1 PF07833.11 KXZ55136.1 - 0.11 13.0 0.1 0.31 11.5 0.1 1.7 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain PFL-like PF02901.15 KXZ55137.1 - 1.9e-190 634.8 0.0 2.5e-190 634.4 0.0 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 KXZ55137.1 - 3.2e-41 140.2 0.0 8.7e-41 138.8 0.0 1.8 1 0 0 1 1 1 1 Glycine radical DUF3029 PF11230.8 KXZ55137.1 - 0.037 12.4 0.0 0.13 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3029) PDEase_I_N PF08499.12 KXZ55137.1 - 0.12 12.2 0.0 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal PFL-like PF02901.15 KXZ55138.1 - 3.1e-190 634.1 0.0 4.7e-190 633.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 KXZ55138.1 - 4e-40 136.6 0.0 1e-39 135.3 0.0 1.8 1 0 0 1 1 1 1 Glycine radical Lectin_C_term PF18022.1 KXZ55138.1 - 0.05 14.1 0.0 18 5.9 0.0 2.8 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin C-terminal domain DUF3029 PF11230.8 KXZ55138.1 - 0.062 11.7 0.0 0.15 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) OGG_N PF07934.12 KXZ55139.1 - 4e-26 91.5 0.0 8.2e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain WD40 PF00400.32 KXZ55139.1 - 3.5e-16 59.3 7.4 7.8e-07 29.7 0.1 7.9 8 0 0 8 8 7 3 WD domain, G-beta repeat HhH-GPD PF00730.25 KXZ55139.1 - 2.1e-13 50.7 0.0 5.6e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein ANAPC4_WD40 PF12894.7 KXZ55139.1 - 2e-10 40.8 0.0 0.037 14.3 0.0 5.6 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KXZ55139.1 - 0.00012 22.0 5.4 0.0044 16.9 1.4 3.6 3 1 0 3 3 3 1 Region in Clathrin and VPS HHH PF00633.23 KXZ55139.1 - 0.0011 18.8 1.1 0.0079 16.0 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif Coatomer_WDAD PF04053.14 KXZ55139.1 - 0.0044 16.1 0.5 0.0044 16.1 0.5 3.8 5 0 0 5 5 5 1 Coatomer WD associated region TPR_7 PF13176.6 KXZ55139.1 - 0.01 15.8 1.0 0.65 10.1 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_2 PF12826.7 KXZ55139.1 - 0.033 14.3 0.0 7.3 6.8 0.0 3.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KXZ55139.1 - 0.1 13.2 0.0 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_19 PF14559.6 KXZ55139.1 - 0.17 12.4 7.8 14 6.3 0.3 4.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ55139.1 - 2.5 8.4 7.9 9.6 6.5 0.1 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KXZ55139.1 - 3 8.0 6.5 26 5.0 1.0 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KXZ55139.1 - 5.4 7.4 12.3 4.3 7.7 0.4 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat GST_N_3 PF13417.6 KXZ55141.1 - 4.6e-17 62.2 0.1 1.7e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXZ55141.1 - 8.3e-14 51.7 0.0 1.7e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ55141.1 - 5e-06 26.4 0.0 1.7e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXZ55141.1 - 7.5e-05 23.0 0.0 0.00022 21.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXZ55141.1 - 0.00011 22.7 0.0 0.00021 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXZ55141.1 - 0.00023 21.8 0.0 0.00068 20.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 KXZ55141.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXZ55141.1 - 0.025 14.8 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin GST_C PF00043.25 KXZ55141.1 - 0.026 14.7 0.0 0.084 13.1 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain KASH_CCD PF14662.6 KXZ55142.1 - 0.0018 18.1 0.5 0.0018 18.1 0.5 4.2 3 1 1 4 4 4 2 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 KXZ55142.1 - 0.022 14.9 0.8 0.022 14.9 0.8 4.2 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF2205 PF10224.9 KXZ55142.1 - 0.046 13.7 0.5 0.046 13.7 0.5 4.9 4 2 1 5 5 5 0 Short coiled-coil protein YabA PF06156.13 KXZ55142.1 - 0.065 13.9 0.7 0.065 13.9 0.7 5.3 3 2 2 5 5 5 0 Initiation control protein YabA CCDC144C PF14915.6 KXZ55142.1 - 1.7 7.7 41.0 0.051 12.7 4.9 4.3 3 1 0 3 3 3 0 CCDC144C protein coiled-coil region FapA PF03961.13 KXZ55142.1 - 1.8 7.1 14.2 0.12 11.0 0.2 3.3 3 1 1 4 4 4 0 Flagellar Assembly Protein A Fez1 PF06818.15 KXZ55142.1 - 4.3 7.8 38.7 7.3 7.0 0.2 3.9 3 1 0 3 3 3 0 Fez1 TMF_DNA_bd PF12329.8 KXZ55142.1 - 6.3 6.9 34.9 1.6 8.8 1.2 5.6 5 2 1 6 6 6 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 KXZ55142.1 - 7.9 5.8 41.1 0.5 9.7 7.4 4.6 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding CTU2 PF10288.9 KXZ55143.1 - 2.6e-05 24.4 2.5 0.00026 21.2 2.5 2.8 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 DUF5476 PF17570.2 KXZ55143.1 - 0.4 11.1 1.9 0.41 11.1 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5476) TFIIA PF03153.13 KXZ55143.1 - 0.85 9.6 10.8 1.5 8.8 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-O PF09496.10 KXZ55143.1 - 3.5 7.5 6.5 8 6.4 6.3 1.7 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component PseudoU_synth_2 PF00849.22 KXZ55145.1 - 2.4e-17 63.5 0.0 9.4e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KXZ55145.1 - 4.4e-09 35.9 0.1 4.4e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 S4 domain LRR_4 PF12799.7 KXZ55146.1 - 1e-10 41.7 0.5 0.00042 20.6 0.0 4.3 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXZ55146.1 - 9.9e-06 25.2 0.0 3.1e-05 23.6 0.0 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KXZ55146.1 - 0.00028 20.6 1.8 3.8 7.3 1.4 3.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KXZ55146.1 - 0.0043 17.0 0.8 0.1 12.7 0.0 3.5 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KXZ55146.1 - 0.33 11.7 1.1 2e+02 3.2 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat Tubulin_3 PF14881.6 KXZ55147.1 - 1.4e-14 54.2 0.0 1.6e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KXZ55147.1 - 2.3e-12 47.3 0.0 3.3e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KXZ55147.1 - 0.0082 16.4 0.0 0.0082 16.4 0.0 2.5 2 1 1 3 3 3 1 Tubulin/FtsZ family, GTPase domain LsmAD PF06741.13 KXZ55151.1 - 3.5e-18 65.9 0.0 7.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 KXZ55151.1 - 2.4e-12 46.8 0.0 4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 KXZ55151.1 - 6.3e-08 31.8 6.4 0.00012 21.5 0.8 2.7 1 1 1 2 2 2 2 Ataxin-2 C-terminal region PsbX PF06596.11 KXZ55153.1 - 2.5 8.2 6.8 5.7 7.0 6.8 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) EF-hand_1 PF00036.32 KXZ55154.1 - 4.8e-09 35.1 0.3 0.00038 19.8 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXZ55154.1 - 1.5e-08 35.0 0.0 3.5e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXZ55154.1 - 1.1e-05 25.1 0.3 2.2e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ55154.1 - 3e-05 23.6 0.0 0.086 12.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain DnaJ_CXXCXGXG PF00684.19 KXZ55154.1 - 0.00015 22.1 0.9 0.00036 20.8 0.9 1.6 1 0 0 1 1 1 1 DnaJ central domain EF-hand_5 PF13202.6 KXZ55154.1 - 0.00094 18.6 0.1 0.015 14.7 0.1 2.4 2 0 0 2 2 2 1 EF hand Glyco_hydro_14 PF01373.17 KXZ55155.1 - 9.2e-95 317.9 0.0 5.1e-71 239.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 Methyltransf_10 PF05971.12 KXZ55155.1 - 6.7e-57 193.1 2.3 6e-36 124.3 0.1 3.1 2 1 0 2 2 2 2 RNA methyltransferase MTS PF05175.14 KXZ55155.1 - 0.0054 16.3 0.1 0.04 13.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain ATP_synt_H PF05493.13 KXZ55156.1 - 2.1e-18 66.5 4.0 2.2e-18 66.4 4.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF3382 PF11862.8 KXZ55156.1 - 0.011 16.0 0.7 0.012 15.8 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) zf-HIT PF04438.16 KXZ55157.1 - 2.4e-07 30.5 18.1 3.6e-07 29.9 18.1 1.3 1 0 0 1 1 1 1 HIT zinc finger UBA2_C PF16195.5 KXZ55157.1 - 0.012 16.3 2.9 0.012 16.3 2.9 1.7 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus CDC45 PF02724.14 KXZ55157.1 - 0.13 10.6 2.1 0.14 10.4 2.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 KXZ55157.1 - 3.3 8.2 9.5 9 6.7 9.5 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal C1_2 PF03107.16 KXZ55157.1 - 5.2 7.5 15.3 28 5.1 15.3 2.0 1 1 0 1 1 1 0 C1 domain SRCR PF00530.18 KXZ55161.1 - 2.8e-110 361.5 30.3 1.4e-21 76.9 0.4 7.4 6 1 0 6 6 6 6 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KXZ55161.1 - 1.3e-20 73.8 21.8 0.00043 20.8 0.1 6.9 7 0 0 7 7 7 5 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KXZ55161.1 - 1.2e-07 32.2 0.7 11 6.6 0.0 5.4 5 0 0 5 5 5 2 Hepsin, SRCR domain Trypsin PF00089.26 KXZ55161.1 - 3.7e-05 23.6 0.2 8.5e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Trypsin Beta_helix PF13229.6 KXZ55163.1 - 8.9e-11 41.9 0.1 0.00017 21.5 0.0 3.0 2 1 1 3 3 3 2 Right handed beta helix region TRP PF06011.12 KXZ55163.1 - 2.2e-06 26.7 11.4 4.2e-06 25.7 11.4 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Ephrin_rec_like PF07699.13 KXZ55163.1 - 3.2e-05 23.6 2.9 3.2e-05 23.6 2.9 2.4 2 0 0 2 2 2 1 Putative ephrin-receptor like NosD PF05048.13 KXZ55163.1 - 0.016 14.5 0.1 0.34 10.1 0.6 2.2 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) MSC PF09402.10 KXZ55163.1 - 2 7.8 4.0 4 6.8 4.0 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain NCD3G PF07562.14 KXZ55163.1 - 3.1 7.9 9.3 2.6 8.1 4.4 2.7 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR EMC1_C PF07774.13 KXZ55164.1 - 8.3e-58 195.6 0.0 1.2e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Gram_pos_anchor PF00746.21 KXZ55164.1 - 1.3 9.0 4.8 0.37 10.8 0.6 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif EF-hand_6 PF13405.6 KXZ55165.1 - 0.00058 19.6 0.1 0.0019 18.0 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KXZ55165.1 - 0.00088 18.7 0.1 0.0018 17.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KXZ55165.1 - 0.0018 17.7 0.4 0.0042 16.5 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXZ55165.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair PRA1 PF03208.19 KXZ55165.1 - 0.09 12.4 0.1 0.09 12.4 0.1 1.5 2 0 0 2 2 2 0 PRA1 family protein Aconitase PF00330.20 KXZ55166.1 - 1e-150 502.8 0.0 1.3e-150 502.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXZ55166.1 - 1.8e-45 154.5 0.0 4.9e-45 153.1 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain NAD_binding_10 PF13460.6 KXZ55167.1 - 3.7e-22 79.1 0.0 6.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXZ55167.1 - 1.4e-17 64.1 0.0 1.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXZ55167.1 - 1.1e-11 44.6 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ55167.1 - 3.6e-06 26.2 0.0 5.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXZ55167.1 - 0.00076 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXZ55167.1 - 0.00079 18.6 0.0 0.0015 17.7 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KXZ55167.1 - 0.0016 18.5 0.7 0.091 12.9 0.7 2.4 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KXZ55167.1 - 0.011 15.2 0.1 0.025 14.0 0.1 1.6 1 1 1 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KXZ55167.1 - 0.018 14.2 0.1 0.52 9.4 0.1 2.5 1 1 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.17 KXZ55167.1 - 0.047 12.8 0.0 0.098 11.7 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4658 PF15555.6 KXZ55167.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Cyt-b5 PF00173.28 KXZ55168.1 - 3.2e-18 65.6 0.0 1.8e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain RrnaAD PF00398.20 KXZ55169.1 - 1.4e-50 171.8 0.0 1.3e-48 165.4 0.0 2.1 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KXZ55169.1 - 0.00092 19.9 0.0 0.002 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PPS_PS PF02006.16 KXZ55169.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Methyltransf_23 PF13489.6 KXZ55169.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ55169.1 - 0.029 15.1 0.0 0.068 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ55169.1 - 0.05 14.2 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KXZ55169.1 - 0.19 11.4 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DIE2_ALG10 PF04922.12 KXZ55170.1 - 4.4e-32 111.8 1.9 5.4e-32 111.5 1.9 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Eapp_C PF10238.9 KXZ55171.1 - 3.2e-38 131.1 2.1 6.6e-37 126.9 2.1 2.0 1 1 0 1 1 1 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.14 KXZ55171.1 - 0.11 12.7 0.3 5.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly UPF0547 PF10571.9 KXZ55171.1 - 0.18 11.9 0.2 0.18 11.9 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RhlB PF12300.8 KXZ55171.1 - 1.4 9.0 9.7 0.1 12.7 4.6 1.7 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB CPBP PF02517.16 KXZ55172.1 - 6.9e-07 29.5 2.8 6.9e-07 29.5 2.8 1.6 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Bystin PF05291.11 KXZ55173.1 - 3.1e-113 377.9 0.0 9.6e-56 189.2 0.0 2.1 2 0 0 2 2 2 2 Bystin DUF3301 PF11743.8 KXZ55173.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) UPF0047 PF01894.17 KXZ55175.1 - 9.6e-31 106.3 0.0 1.2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 SNARE_assoc PF09335.11 KXZ55176.1 - 2.6e-25 89.2 4.8 4.5e-25 88.5 4.8 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein Alginate_lyase PF05426.12 KXZ55176.1 - 0.061 12.9 0.1 0.092 12.3 0.1 1.2 1 0 0 1 1 1 0 Alginate lyase Radical_SAM PF04055.21 KXZ55177.1 - 1.8e-15 57.8 0.0 3.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KXZ55177.1 - 0.00031 20.9 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KXZ55177.1 - 0.059 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF1206 PF06724.11 KXZ55177.1 - 0.16 12.0 4.1 0.41 10.8 4.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) UPF0220 PF05255.11 KXZ55178.1 - 2.6e-24 85.6 0.5 3.2e-24 85.4 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4131 PF13567.6 KXZ55178.1 - 0.48 10.1 4.5 3.9 7.1 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 KXZ55179.1 - 1.1e-43 149.5 0.0 1.5e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55179.1 - 1.9e-42 145.4 0.0 2.5e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ55179.1 - 0.00063 19.7 0.3 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ55179.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXZ55179.1 - 0.23 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ55180.1 - 4.7e-30 104.9 0.0 6.4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55180.1 - 3.3e-25 88.8 0.0 4.7e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ55180.1 - 0.00089 19.2 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ55180.1 - 0.043 12.6 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Gly-zipper_Omp PF13488.6 KXZ55180.1 - 0.38 10.8 7.9 0.72 9.9 7.9 1.4 1 0 0 1 1 1 0 Glycine zipper Carb_kinase PF01256.17 KXZ55181.1 - 1.5e-43 149.0 0.0 2.8e-41 141.6 0.0 2.2 1 1 0 1 1 1 1 Carbohydrate kinase Hydrolase_4 PF12146.8 KXZ55182.1 - 6.5e-45 153.3 0.0 8.8e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ55182.1 - 2.5e-09 38.1 2.2 3.6e-09 37.5 2.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXZ55182.1 - 3.5e-07 30.1 0.0 1.3e-05 25.0 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXZ55182.1 - 0.00036 20.1 0.0 0.0044 16.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 KXZ55182.1 - 0.0004 20.1 0.4 0.0013 18.4 0.1 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 KXZ55182.1 - 0.0031 17.3 0.0 0.98 9.2 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KXZ55182.1 - 0.0079 16.1 0.4 0.031 14.2 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KXZ55182.1 - 0.046 13.5 0.0 6.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ55183.1 - 3.2e-46 157.5 0.0 4.2e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXZ55183.1 - 7.3e-06 25.8 0.2 0.00089 19.0 0.4 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXZ55183.1 - 0.00019 21.0 0.0 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KXZ55183.1 - 0.00029 20.6 0.0 0.052 13.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXZ55183.1 - 0.0012 18.7 0.2 0.0036 17.2 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXZ55183.1 - 0.02 14.6 0.1 0.042 13.5 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 KXZ55183.1 - 0.11 12.3 0.2 0.9 9.3 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Med7 PF05983.11 KXZ55184.1 - 1.9e-23 83.6 14.4 1.2e-21 77.7 14.4 2.2 1 1 0 1 1 1 1 MED7 protein zf-LITAF-like PF10601.9 KXZ55184.1 - 4.6e-05 23.6 11.8 7.2e-05 23.0 11.8 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain TolA_bind_tri PF16331.5 KXZ55184.1 - 0.079 13.0 0.5 0.61 10.2 0.4 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation NeA_P2 PF12312.8 KXZ55184.1 - 1.8 7.9 4.8 1 8.7 2.6 1.7 1 1 0 1 1 1 0 Nepovirus subgroup A polyprotein Mito_fiss_reg PF05308.11 KXZ55184.1 - 6.7 6.7 10.5 3.4 7.7 0.8 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator PfkB PF00294.24 KXZ55185.1 - 2.5e-35 122.3 3.2 5.2e-34 117.9 3.2 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Lysine_decarbox PF03641.14 KXZ55185.1 - 6.5e-18 65.1 0.0 1.2e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase PetN PF03742.14 KXZ55187.1 - 2.1e-12 46.6 5.1 2.1e-12 46.6 5.1 2.1 2 1 0 2 2 2 1 PetN DUF3275 PF11679.8 KXZ55187.1 - 0.3 11.0 1.3 0.33 10.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Nodulin-like PF06813.13 KXZ55188.1 - 3.2e-38 131.7 1.6 3.2e-38 131.7 1.6 2.2 2 0 0 2 2 2 1 Nodulin-like Nha1_C PF08619.10 KXZ55188.1 - 0.16 11.2 10.3 0.22 10.7 10.3 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus FXR_C1 PF16096.5 KXZ55188.1 - 0.95 9.7 4.8 1.8 8.8 4.8 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 SRP-alpha_N PF04086.13 KXZ55188.1 - 8.6 6.2 7.2 12 5.7 7.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_L26 PF16906.5 KXZ55189.1 - 2.4e-37 127.3 2.4 3e-37 126.9 2.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KXZ55189.1 - 7.4e-08 32.1 1.6 7.4e-08 32.1 1.6 2.3 2 0 0 2 2 2 1 KOW motif Lactamase_B_2 PF12706.7 KXZ55190.1 - 1.4e-15 57.3 0.5 2.1e-06 27.4 0.4 3.3 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KXZ55190.1 - 9e-13 47.7 0.0 1.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KXZ55190.1 - 7.3e-06 26.1 0.0 2.8e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ABC2_membrane PF01061.24 KXZ55191.1 - 9.3e-75 250.6 56.8 2.4e-38 131.7 26.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXZ55191.1 - 1.3e-30 106.7 0.0 5.1e-15 56.2 0.0 3.3 3 0 0 3 3 3 3 ABC transporter PDR_assoc PF08370.11 KXZ55191.1 - 2.1e-08 33.8 0.0 2.1e-08 33.8 0.0 2.5 4 0 0 4 4 1 1 Plant PDR ABC transporter associated AAA_29 PF13555.6 KXZ55191.1 - 1.8e-07 30.8 0.5 0.028 14.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ55191.1 - 1.4e-06 28.8 0.5 0.014 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KXZ55191.1 - 3.3e-06 26.8 0.7 0.022 14.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KXZ55191.1 - 2.3e-05 24.3 0.0 0.08 12.7 0.0 3.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXZ55191.1 - 2.7e-05 23.5 10.7 2.7e-05 23.5 10.7 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KXZ55191.1 - 0.00012 22.0 0.3 0.081 12.8 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXZ55191.1 - 0.00013 22.3 1.0 0.069 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXZ55191.1 - 0.00043 20.1 0.8 0.89 9.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KXZ55191.1 - 0.00047 20.6 0.3 0.11 12.9 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KXZ55191.1 - 0.0037 17.8 0.1 1.3 9.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXZ55191.1 - 0.004 17.4 2.5 2.6 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXZ55191.1 - 0.0057 16.7 0.5 1.4 9.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KXZ55191.1 - 0.0058 17.2 0.6 3.6 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXZ55191.1 - 0.0096 15.9 1.3 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KXZ55191.1 - 0.013 15.5 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 KXZ55191.1 - 0.017 14.9 0.5 5.1 6.8 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KXZ55191.1 - 0.026 14.7 1.1 5.3 7.2 0.1 2.8 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KXZ55191.1 - 0.043 13.8 0.3 25 4.9 0.2 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KXZ55191.1 - 0.059 13.0 2.1 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KXZ55191.1 - 0.11 12.0 0.2 35 3.7 0.0 3.3 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain DLIC PF05783.11 KXZ55191.1 - 0.14 11.0 1.0 7.9 5.2 0.3 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) SbcCD_C PF13558.6 KXZ55191.1 - 0.14 12.4 0.0 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 KXZ55191.1 - 0.18 11.4 0.1 2.3 7.8 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KXZ55191.1 - 0.42 10.9 1.4 10 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KXZ55191.1 - 0.58 10.1 5.3 11 5.8 0.0 3.2 4 0 0 4 4 3 0 NACHT domain Mg_chelatase PF01078.21 KXZ55191.1 - 1.1 8.6 2.8 1.7 8.0 0.1 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Ank_2 PF12796.7 KXZ55194.1 - 7.3e-15 55.3 0.3 0.0045 17.5 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ55194.1 - 2.4e-13 50.3 3.9 0.087 13.4 0.0 6.8 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55194.1 - 1.7e-08 34.0 1.9 8.1 7.4 0.0 8.6 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 KXZ55194.1 - 0.0022 18.3 4.5 10 6.6 0.0 5.4 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ55194.1 - 0.26 11.8 1.2 17 6.1 0.1 4.1 2 2 0 2 2 2 0 Ankyrin repeat Defensin_4 PF07936.12 KXZ55194.1 - 9.3 6.2 8.6 73 3.4 0.0 4.4 4 0 0 4 4 4 0 Potassium-channel blocking toxin Histone PF00125.24 KXZ55195.1 - 4e-19 69.3 1.6 5.4e-19 68.9 1.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ55195.1 - 1.5e-05 25.2 1.7 1.7e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ55195.1 - 0.0011 19.4 0.0 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ55195.1 - 0.0013 18.8 0.7 0.0015 18.6 0.7 1.1 1 0 0 1 1 1 1 YscO-like protein 4HB_MCP_1 PF12729.7 KXZ55195.1 - 0.0044 16.6 0.9 0.0059 16.2 0.9 1.1 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction RP-C PF03428.13 KXZ55195.1 - 0.045 13.4 0.3 0.24 11.1 0.3 1.9 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H-assoc PF13902.6 KXZ55196.1 - 2.6e-13 50.5 1.7 4.6e-13 49.7 1.7 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KXZ55196.1 - 0.0015 18.4 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 R3H domain TPK_catalytic PF04263.16 KXZ55197.1 - 1.8e-31 108.7 0.0 1.8e-30 105.4 0.0 2.1 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KXZ55197.1 - 4.2e-16 58.4 0.0 8.2e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Av_adeno_fibre PF06536.11 KXZ55197.1 - 0.0069 16.2 0.2 0.024 14.5 0.2 1.9 1 0 0 1 1 1 1 Avian adenovirus fibre, N-terminal Pkinase PF00069.25 KXZ55198.1 - 7e-21 74.8 0.0 1.9e-19 70.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55198.1 - 5.8e-20 71.7 0.0 5.7e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ55198.1 - 0.00031 19.6 0.0 0.0073 15.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXZ55198.1 - 0.0089 16.0 0.1 0.026 14.5 0.1 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ55198.1 - 0.03 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GAF_2 PF13185.6 KXZ55198.1 - 0.071 13.4 0.4 0.33 11.2 0.1 2.4 2 0 0 2 2 2 0 GAF domain DUF2475 PF10629.9 KXZ55199.1 - 0.085 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Pkinase PF00069.25 KXZ55200.1 - 1.7e-43 148.9 0.0 9.4e-37 126.8 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55200.1 - 3e-30 105.4 0.0 1.5e-25 90.0 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ55200.1 - 0.041 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ55200.1 - 0.044 12.6 0.0 0.081 11.7 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KXZ55201.1 - 1.6e-56 191.6 0.0 2.8e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55201.1 - 4.5e-40 137.6 0.0 7.8e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KXZ55201.1 - 0.00045 20.4 0.5 0.00076 19.6 0.5 1.4 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain SNF5 PF04855.12 KXZ55201.1 - 0.023 14.5 1.2 0.047 13.5 1.2 1.5 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 DUF2089 PF09862.9 KXZ55201.1 - 0.21 11.6 0.7 0.59 10.2 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) DUF3752 PF12572.8 KXZ55202.1 - 1.9e-07 31.7 2.1 2.2e-07 31.5 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) FAM117 PF15388.6 KXZ55203.1 - 0.0056 16.1 3.9 0.0063 16.0 3.9 1.1 1 0 0 1 1 1 1 Protein Family FAM117 TruD PF01142.18 KXZ55203.1 - 0.072 11.9 0.9 0.094 11.5 0.9 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) AP3D1 PF06375.11 KXZ55203.1 - 0.12 12.6 16.7 0.15 12.3 16.7 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 AAA_13 PF13166.6 KXZ55203.1 - 0.16 10.6 4.9 0.46 9.1 4.2 1.8 2 0 0 2 2 2 0 AAA domain VSG_B PF13206.6 KXZ55203.1 - 0.2 10.9 3.2 0.22 10.7 3.2 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain CMS1 PF14617.6 KXZ55203.1 - 0.22 10.9 9.3 0.26 10.6 9.3 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TFIIF_alpha PF05793.12 KXZ55203.1 - 0.28 9.7 14.0 0.35 9.4 14.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Seadorna_VP6 PF07407.11 KXZ55203.1 - 0.5 9.3 2.3 0.61 9.0 2.3 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DNApol_Exo PF18136.1 KXZ55203.1 - 0.52 9.4 5.5 0.65 9.1 5.5 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain CDC45 PF02724.14 KXZ55203.1 - 0.59 8.4 7.6 0.65 8.2 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein RabGAP-TBC PF00566.18 KXZ55203.1 - 0.59 9.7 3.5 0.79 9.3 3.5 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Presenilin PF01080.17 KXZ55203.1 - 5.1 5.8 3.8 5 5.8 3.8 1.0 1 0 0 1 1 1 0 Presenilin DUF755 PF05501.11 KXZ55203.1 - 6.8 7.0 26.8 23 5.3 23.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF755) Methyltransf_3 PF01596.17 KXZ55204.1 - 1.1e-12 47.7 0.0 2.8e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXZ55204.1 - 1.7e-11 45.1 0.0 3.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3493 PF11998.8 KXZ55204.1 - 0.00016 21.8 0.6 0.0004 20.5 0.2 1.8 2 0 0 2 2 2 1 Low psii accumulation1 / Rep27 CmcI PF04989.12 KXZ55204.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase NAD_binding_3 PF03447.16 KXZ55204.1 - 0.082 13.6 0.0 0.39 11.4 0.0 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain PCMT PF01135.19 KXZ55204.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Hpt PF01627.23 KXZ55205.1 - 5.7e-12 45.7 0.8 6.9e-12 45.5 0.8 1.2 1 0 0 1 1 1 1 Hpt domain Histone_H2A_C PF16211.5 KXZ55206.1 - 2.3e-19 68.8 1.4 4.2e-19 68.0 1.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ55206.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ55206.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-RING_4 PF14570.6 KXZ55207.1 - 1.3e-14 53.7 9.6 2e-14 53.1 9.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KXZ55207.1 - 2.5e-05 24.0 6.1 4e-05 23.4 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ55207.1 - 0.0013 19.0 8.9 0.0019 18.5 8.9 1.3 1 0 0 1 1 1 1 Ring finger domain Presenilin PF01080.17 KXZ55207.1 - 0.0029 16.4 11.1 0.0039 16.0 11.1 1.2 1 0 0 1 1 1 1 Presenilin Macoilin PF09726.9 KXZ55207.1 - 0.018 13.7 13.9 0.026 13.1 13.9 1.2 1 0 0 1 1 1 0 Macoilin family zf-C3HC4 PF00097.25 KXZ55207.1 - 0.055 13.4 9.7 0.089 12.7 9.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXZ55207.1 - 0.069 13.0 9.7 0.11 12.4 9.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ55207.1 - 0.082 12.8 7.7 2.8 7.9 7.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PAT1 PF09770.9 KXZ55207.1 - 0.099 10.9 23.0 0.12 10.7 23.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 KXZ55207.1 - 0.15 12.1 9.1 0.23 11.5 9.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Baculo_IE-1 PF05290.11 KXZ55207.1 - 0.53 10.2 4.8 0.93 9.4 4.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) MMR1 PF08505.10 KXZ55207.1 - 0.65 10.2 22.0 1.1 9.5 22.0 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Apt1 PF10351.9 KXZ55207.1 - 1.1 8.0 13.7 1.5 7.6 13.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MRP-S31 PF15433.6 KXZ55207.1 - 1.4 8.5 14.3 2.1 7.9 14.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 GREB1 PF15782.5 KXZ55207.1 - 3 4.8 18.4 3.6 4.6 18.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Endostatin PF06482.11 KXZ55207.1 - 3.2 7.2 17.1 4.8 6.6 17.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MAJIN PF15077.6 KXZ55207.1 - 3.3 7.4 10.0 5.6 6.7 10.0 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein RAP1 PF07218.11 KXZ55207.1 - 6.7 4.9 5.8 30 2.7 6.9 1.5 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) eIF-3_zeta PF05091.12 KXZ55207.1 - 7.5 5.4 15.7 11 4.9 15.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 KXZ55207.1 - 9.2 5.7 21.9 15 5.0 21.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BORG_CEP PF14957.6 KXZ55207.1 - 9.7 7.4 20.4 2.5 9.3 16.9 1.8 2 0 0 2 2 1 0 Cdc42 effector DUF4605 PF15378.6 KXZ55208.1 - 3.1e-05 23.7 2.2 4.6e-05 23.2 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) Beta_helix PF13229.6 KXZ55209.1 - 1.3e-05 25.1 0.2 2e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 KXZ55209.1 - 1.9 9.1 20.7 18 6.0 1.7 6.2 5 1 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ribonucleas_3_3 PF14622.6 KXZ55210.1 - 3.9e-16 59.4 0.0 1.4e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXZ55210.1 - 5.9e-16 59.0 0.0 1.7e-15 57.5 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain GDYXXLXY PF14345.6 KXZ55210.1 - 0.034 14.0 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 GDYXXLXY protein Peptidase_M16_M PF16187.5 KXZ55212.1 - 6.3e-54 183.2 0.0 6.9e-53 179.7 0.0 2.0 1 1 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KXZ55212.1 - 2.6e-32 111.8 0.0 5.6e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXZ55212.1 - 3.2e-26 92.5 0.0 1.1e-11 45.0 0.0 2.5 2 1 0 2 2 2 2 Peptidase M16 inactive domain Nop14 PF04147.12 KXZ55212.1 - 0.071 11.3 9.3 0.1 10.8 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXZ55212.1 - 0.25 10.7 11.7 0.44 9.9 11.7 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXZ55212.1 - 6.5 6.0 14.3 12 5.0 14.3 1.4 1 0 0 1 1 1 0 BUD22 Glyco_transf_49 PF13896.6 KXZ55213.1 - 5.7e-30 104.8 0.1 4.3e-16 59.2 0.1 3.1 1 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan MRFAP1 PF15155.6 KXZ55216.1 - 0.00015 22.3 0.1 0.00043 20.8 0.1 1.7 1 0 0 1 1 1 1 MORF4 family-associated protein1 DUF4687 PF15747.5 KXZ55217.1 - 0.14 12.6 6.6 0.2 12.2 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) Ank_2 PF12796.7 KXZ55218.1 - 1.5e-09 38.3 0.0 0.073 13.7 0.0 4.3 2 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ55218.1 - 3.5e-09 37.0 2.8 0.89 10.2 0.2 6.1 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55218.1 - 4e-06 26.8 1.6 11 6.9 0.0 7.4 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 KXZ55218.1 - 0.0018 18.5 1.1 1.1 9.6 0.0 4.5 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Defensin_4 PF07936.12 KXZ55218.1 - 4.5 7.2 8.7 31 4.6 0.5 3.9 4 0 0 4 4 4 0 Potassium-channel blocking toxin DUF2182 PF09948.9 KXZ55221.1 - 0.048 13.5 0.2 0.084 12.7 0.2 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) CobS PF02654.15 KXZ55222.1 - 3.7e-43 148.1 20.8 5.2e-43 147.6 20.8 1.2 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase UBM PF14377.6 KXZ55223.1 - 5.3 6.6 8.7 7.5 6.1 1.1 2.9 3 0 0 3 3 3 0 Ubiquitin binding region mTERF PF02536.14 KXZ55224.1 - 0.00034 19.7 0.0 0.00038 19.5 0.0 1.0 1 0 0 1 1 1 1 mTERF Pro_isomerase PF00160.21 KXZ55225.1 - 1.2e-39 136.1 0.1 1e-38 133.1 0.1 2.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 KXZ55225.1 - 1.9e-16 60.9 4.6 1.9e-16 60.9 4.6 3.5 2 1 2 4 4 4 2 SYF2 splicing factor 4HBT PF03061.22 KXZ55226.1 - 2.2e-10 40.7 3.6 0.00031 21.0 0.0 2.7 3 0 0 3 3 3 2 Thioesterase superfamily 4HBT_3 PF13622.6 KXZ55226.1 - 0.0007 19.9 2.8 0.0007 19.9 2.8 1.7 2 1 0 2 2 2 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 KXZ55226.1 - 0.019 15.5 0.0 3 8.4 0.0 2.5 2 2 0 2 2 2 0 Thioesterase-like superfamily ApoO PF09769.9 KXZ55227.1 - 0.019 14.9 13.4 0.31 11.0 0.1 4.3 3 2 0 3 3 3 0 Apolipoprotein O IL10 PF00726.17 KXZ55227.1 - 0.36 10.3 1.5 19 4.7 0.1 3.5 3 0 0 3 3 3 0 Interleukin 10 TMF_TATA_bd PF12325.8 KXZ55227.1 - 0.41 10.9 44.7 0.65 10.2 4.0 6.4 1 1 6 7 7 7 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 KXZ55227.1 - 0.47 11.1 15.8 14 6.4 0.1 5.4 2 1 3 5 5 5 0 Initiation control protein YabA DUF4201 PF13870.6 KXZ55227.1 - 0.54 10.0 7.5 0.33 10.7 0.4 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) TelA PF05816.11 KXZ55227.1 - 1.3 8.0 40.6 0.72 8.9 7.5 3.3 3 0 0 3 3 3 0 Toxic anion resistance protein (TelA) Fez1 PF06818.15 KXZ55227.1 - 2.5 8.5 46.1 0.33 11.4 9.7 3.4 1 1 2 3 3 3 0 Fez1 TolA_bind_tri PF16331.5 KXZ55227.1 - 4 7.6 24.5 2.3 8.3 0.8 5.6 6 0 0 6 6 6 0 TolA binding protein trimerisation MMR_HSR1_Xtn PF16897.5 KXZ55228.1 - 2.2e-41 140.2 0.3 4e-41 139.3 0.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXZ55228.1 - 5.2e-20 71.6 0.0 1.5e-19 70.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KXZ55228.1 - 1.1e-19 70.2 0.0 2e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KXZ55228.1 - 1.1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXZ55228.1 - 0.0001 22.4 0.1 0.064 13.3 0.0 2.3 1 1 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KXZ55228.1 - 0.054 13.4 0.7 3.3 7.6 0.1 3.2 2 1 1 3 3 3 0 RsgA GTPase SRPRB PF09439.10 KXZ55228.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Calreticulin PF00262.18 KXZ55229.1 - 8.1e-83 278.3 15.9 3.2e-60 203.9 4.4 2.2 1 1 1 2 2 2 2 Calreticulin family p450 PF00067.22 KXZ55231.1 - 7.6e-63 212.8 0.0 1e-62 212.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXZ55232.1 - 1.6e-09 37.0 0.0 2.1e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_4 PF13439.6 KXZ55233.1 - 7.4e-22 78.1 0.1 1.6e-21 77.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXZ55233.1 - 1.4e-16 61.3 0.6 1.4e-16 61.3 0.6 3.3 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KXZ55233.1 - 9.1e-06 25.7 0.0 3.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glycos_transf_1 PF00534.20 KXZ55233.1 - 0.067 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 CCDC50_N PF15295.6 KXZ55234.1 - 0.58 10.3 15.1 0.73 10.0 15.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Sarcolipin PF05366.11 KXZ55234.1 - 1.4 8.6 4.8 44 3.9 0.0 3.8 4 0 0 4 4 4 0 Sarcolipin CwsA PF10814.8 KXZ55234.1 - 3.7 7.7 9.1 12 6.1 8.7 1.9 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA Glyco_transf_4 PF13439.6 KXZ55235.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KXZ55235.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ55235.1 - 0.065 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 FA_desaturase PF00487.24 KXZ55236.1 - 6.7e-35 121.1 24.1 1e-34 120.5 24.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXZ55236.1 - 7.3e-16 58.6 0.1 1.2e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RRM_1 PF00076.22 KXZ55237.1 - 6.2e-16 58.0 0.0 8.7e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ55237.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2457 PF10446.9 KXZ55237.1 - 0.16 11.1 27.2 0.26 10.4 27.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nup35_RRM_2 PF14605.6 KXZ55237.1 - 0.18 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GRP PF07172.11 KXZ55237.1 - 0.46 11.2 19.2 0.79 10.5 19.2 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF2967 PF11179.8 KXZ55237.1 - 0.47 8.5 22.3 0.12 10.4 19.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2967) Tic110 PF16940.5 KXZ55238.1 - 2.5e-28 98.9 7.2 6e-23 81.2 0.0 4.2 2 1 3 6 6 6 3 Chloroplast envelope transporter Mg_chelatase_C PF13335.6 KXZ55238.1 - 0.061 14.0 0.8 0.061 14.0 0.8 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal LcrG PF07216.12 KXZ55238.1 - 0.35 10.8 0.1 0.35 10.8 0.1 3.4 4 1 0 4 4 4 0 LcrG protein Porin_5 PF16930.5 KXZ55238.1 - 6.8 5.0 14.7 4.6 5.6 0.7 2.2 2 0 0 2 2 2 0 Putative porin ALG11_N PF15924.5 KXZ55239.1 - 1.7e-64 217.7 0.5 1.8e-51 175.2 0.0 2.2 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KXZ55239.1 - 8.9e-25 87.2 0.0 1.4e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ55239.1 - 2.3e-11 44.2 0.1 6e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ55239.1 - 0.00017 21.7 0.6 0.00042 20.4 0.6 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KXZ55239.1 - 0.00026 21.3 0.0 0.00066 20.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Voltage_CLC PF00654.20 KXZ55240.1 - 2.4e-11 43.5 0.2 2.4e-11 43.5 0.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXZ55240.1 - 6e-11 42.6 0.1 1.9e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 CBS domain Bestrophin PF01062.21 KXZ55241.1 - 3.2e-33 115.4 0.3 4e-33 115.1 0.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Retrotrans_gag PF03732.17 KXZ55242.1 - 1.1e-09 38.4 0.1 4.9e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2202 PF09968.9 KXZ55242.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein domain (DUF2202) AAA_22 PF13401.6 KXZ55243.1 - 0.0055 17.0 0.0 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Pkinase PF00069.25 KXZ55244.1 - 3.4e-47 161.0 0.0 1.8e-19 70.2 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55244.1 - 1.2e-22 80.4 0.0 4.1e-09 36.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KXZ55244.1 - 1e-15 58.0 0.0 1.5e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain HGTP_anticodon PF03129.20 KXZ55244.1 - 1.5e-10 41.1 0.0 2.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KXZ55244.1 - 7.1e-07 29.0 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Kinase-like PF14531.6 KXZ55244.1 - 0.0028 17.0 0.1 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like tRNA-synt_His PF13393.6 KXZ55244.1 - 0.0084 15.4 0.0 0.086 12.1 0.0 2.6 3 0 0 3 3 3 1 Histidyl-tRNA synthetase Pyridoxal_deC PF00282.19 KXZ55245.1 - 3e-24 85.4 0.0 1.5e-23 83.2 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXZ55245.1 - 0.0053 15.8 0.0 0.013 14.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V AAA PF00004.29 KXZ55246.1 - 6.6e-46 156.0 0.0 4.3e-40 137.2 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Response_reg PF00072.24 KXZ55246.1 - 1.2e-23 83.5 0.0 6.9e-20 71.3 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain Bac_rhodopsin PF01036.18 KXZ55246.1 - 7.5e-17 61.6 12.1 1.2e-16 61.0 12.1 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HATPase_c PF02518.26 KXZ55246.1 - 2.9e-16 59.9 0.0 1.3e-15 57.9 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_lid_3 PF17862.1 KXZ55246.1 - 6.5e-11 41.9 0.1 2.6e-10 39.9 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KXZ55246.1 - 4.6e-07 29.7 0.0 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Bromodomain PF00439.25 KXZ55246.1 - 8.3e-07 29.0 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain HisKA PF00512.25 KXZ55246.1 - 1.4e-06 28.3 0.0 4.8e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KXZ55246.1 - 5.8e-06 26.8 3.5 1.8e-05 25.2 0.0 3.4 3 0 0 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KXZ55246.1 - 2.1e-05 24.7 0.0 5.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXZ55246.1 - 0.00013 22.0 0.4 0.0043 17.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXZ55246.1 - 0.00031 21.3 0.0 0.0028 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXZ55246.1 - 0.0048 17.2 0.3 0.15 12.3 0.1 3.4 3 1 0 3 3 3 1 AAA domain HATPase_c_3 PF13589.6 KXZ55246.1 - 0.0058 16.5 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mg_chelatase PF01078.21 KXZ55246.1 - 0.0062 15.9 0.5 0.28 10.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXZ55246.1 - 0.017 15.3 0.0 0.11 12.7 0.0 2.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXZ55246.1 - 0.025 15.0 0.0 0.064 13.7 0.0 1.7 2 0 0 2 2 1 0 RNA helicase RuvB_N PF05496.12 KXZ55246.1 - 0.039 13.7 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KXZ55246.1 - 0.061 12.4 0.0 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 KXZ55246.1 - 0.065 12.4 0.0 0.42 9.8 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_33 PF13671.6 KXZ55246.1 - 0.068 13.3 0.3 0.41 10.8 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KXZ55246.1 - 0.089 12.3 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KXZ55246.1 - 1.4 8.7 0.0 1.4 8.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain Helicase_C PF00271.31 KXZ55248.1 - 0.00024 21.4 0.0 0.00068 20.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Biotin_lipoyl PF00364.22 KXZ55249.1 - 4.5e-08 32.8 0.7 9.4e-08 31.8 0.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXZ55249.1 - 1.5e-06 27.9 2.1 0.0011 18.8 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 KXZ55249.1 - 0.0012 18.8 1.7 0.015 15.2 0.3 2.8 3 1 1 4 4 4 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 KXZ55249.1 - 0.022 15.0 2.1 0.78 10.0 1.0 2.6 1 1 1 2 2 2 0 Peptidase family M23 GCV_H PF01597.19 KXZ55249.1 - 0.12 12.3 1.4 0.17 11.8 0.2 1.9 2 1 0 2 2 2 0 Glycine cleavage H-protein ACT PF01842.25 KXZ55250.1 - 9.3e-10 38.1 0.2 2.2e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 KXZ55250.1 - 2.7e-06 27.9 0.2 0.00087 19.8 0.1 2.3 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 KXZ55250.1 - 0.097 12.7 0.2 0.39 10.7 0.1 2.0 2 0 0 2 2 2 0 ACT domain RRM_1 PF00076.22 KXZ55251.1 - 3e-29 100.6 0.0 1.3e-12 47.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 KXZ55251.1 - 2.9e-13 49.2 0.2 2.9e-13 49.2 0.2 1.8 2 0 0 2 2 2 1 SAP domain MIP PF00230.20 KXZ55252.1 - 4.5e-14 52.7 5.1 5.7e-14 52.4 5.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein VIT1 PF01988.19 KXZ55252.1 - 2.6 7.8 10.0 0.32 10.8 3.5 2.2 1 1 1 2 2 2 0 VIT family Pep_deformylase PF01327.21 KXZ55254.1 - 1.6e-37 128.6 0.0 2e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Thioredoxin PF00085.20 KXZ55255.1 - 1.2e-06 28.5 0.3 2.2e-06 27.6 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin DUF1367 PF07105.11 KXZ55255.1 - 0.069 12.8 0.3 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) BLUF PF04940.12 KXZ55256.1 - 0.00057 20.0 0.0 0.00092 19.3 0.0 1.3 1 0 0 1 1 1 1 Sensors of blue-light using FAD ADPrib_exo_Tox PF03496.14 KXZ55256.1 - 0.039 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme CDT1 PF08839.11 KXZ55256.1 - 0.047 14.0 0.0 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 DNA replication factor CDT1 like DUF3087 PF11286.8 KXZ55256.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) ACCA PF03255.14 KXZ55256.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PAC1 PF16094.5 KXZ55257.1 - 2.4e-10 40.0 0.0 4.7e-10 39.1 0.0 1.4 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 FA_desaturase PF00487.24 KXZ55258.1 - 1.8e-32 113.2 12.9 2.7e-32 112.6 12.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXZ55258.1 - 4.7e-13 49.1 0.0 1.4e-12 47.6 0.0 1.8 1 1 1 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain CAMP_factor PF07373.11 KXZ55259.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 CAMP factor (Cfa) Fe_hyd_lg_C PF02906.14 KXZ55261.1 - 1.3e-98 329.5 0.0 5.1e-98 327.6 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KXZ55261.1 - 7.4e-26 90.0 1.0 1.5e-25 89.0 1.0 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Skp1_POZ PF03931.15 KXZ55262.1 - 0.072 13.3 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Abhydrolase_1 PF00561.20 KXZ55263.1 - 1.3e-17 64.3 0.1 6.8e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ55263.1 - 1.6e-08 35.5 26.9 0.0033 18.0 4.0 2.9 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXZ55263.1 - 4.9e-06 26.0 0.0 0.00094 18.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KXZ55263.1 - 0.041 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) MENTAL PF10457.9 KXZ55263.1 - 0.094 12.5 0.4 0.16 11.8 0.4 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain FAD_binding_1 PF00667.20 KXZ55264.1 - 1.1e-60 204.9 0.0 1.7e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXZ55264.1 - 3.4e-28 98.6 0.2 6.6e-28 97.7 0.2 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXZ55264.1 - 4.6e-08 33.7 0.0 1.2e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.22 KXZ55265.1 - 4.9e-86 282.6 1.9 1.3e-22 79.3 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXZ55265.1 - 4.1e-15 55.5 0.3 0.00072 19.2 0.0 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ55265.1 - 5e-13 48.7 0.5 3e-05 23.8 0.0 3.9 5 0 0 5 5 4 3 Occluded RNA-recognition motif RRM_7 PF16367.5 KXZ55265.1 - 2.2e-09 37.3 0.1 0.29 11.3 0.0 5.0 4 2 0 4 4 4 3 RNA recognition motif SET_assoc PF11767.8 KXZ55265.1 - 1.7e-05 24.4 2.1 1.1 9.0 0.1 4.0 4 1 1 5 5 5 2 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 KXZ55265.1 - 0.00016 21.7 2.1 0.35 11.0 0.0 3.8 3 1 1 5 5 4 2 Limkain b1 TC1 PF15063.6 KXZ55265.1 - 0.0047 16.8 0.0 2.2 8.2 0.0 3.6 3 0 0 3 3 3 1 Thyroid cancer protein 1 DbpA PF03880.15 KXZ55265.1 - 0.0087 16.0 0.0 96 3.1 0.0 4.3 4 0 0 4 4 4 0 DbpA RNA binding domain Nefa_Nip30_N PF10187.9 KXZ55265.1 - 0.03 14.7 1.6 3.9 7.9 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 IF2_N PF04760.15 KXZ55265.1 - 0.032 14.0 0.0 2.9 7.8 0.0 2.7 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF4523 PF15023.6 KXZ55265.1 - 0.052 13.4 0.1 3.4 7.5 0.0 3.2 3 1 0 4 4 4 0 Protein of unknown function (DUF4523) OB_RNB PF08206.11 KXZ55265.1 - 0.1 12.3 4.2 6.4 6.5 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KXZ55265.1 - 0.12 12.4 0.0 12 5.9 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif CSD PF00313.22 KXZ55265.1 - 0.13 12.2 2.2 30 4.5 0.2 3.3 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain DHHA1 PF02272.19 KXZ55265.1 - 0.15 12.5 2.5 0.39 11.1 0.3 2.5 1 1 1 2 2 2 0 DHHA1 domain CbiG_mid PF11761.8 KXZ55265.1 - 0.15 12.2 0.0 17 5.6 0.0 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis central region DUF4078 PF13300.6 KXZ55265.1 - 4 7.8 9.3 7.6 6.9 2.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4078) Ribosomal_S5 PF00333.20 KXZ55266.1 - 6.6e-30 102.9 2.3 1.3e-29 101.9 2.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KXZ55266.1 - 2e-26 91.2 0.0 3.4e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PRR20 PF15708.5 KXZ55266.1 - 7.6 6.4 5.9 12 5.8 5.9 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 Roc PF08477.13 KXZ55267.1 - 0.00041 20.6 0.0 0.00071 19.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ55267.1 - 0.00094 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXZ55267.1 - 0.063 12.9 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Ras family Homeodomain PF00046.29 KXZ55267.1 - 0.26 11.1 2.9 1.8 8.5 0.0 2.6 3 0 0 3 3 3 0 Homeodomain TIC20 PF16166.5 KXZ55268.1 - 1.9e-35 122.3 3.4 2.1e-35 122.2 3.4 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like DUF4870 PF09685.10 KXZ55268.1 - 0.053 13.6 5.6 0.074 13.2 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) Sep15_SelM PF08806.11 KXZ55272.1 - 4.3e-11 42.8 0.0 4.9e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain Bax1-I PF01027.20 KXZ55273.1 - 2.7e-33 115.6 17.8 3.3e-33 115.3 17.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KXZ55273.1 - 0.00013 21.6 11.8 0.00019 21.1 11.8 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like DUF1003 PF06210.11 KXZ55273.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DUF417 PF04224.12 KXZ55273.1 - 1.2 8.7 4.4 0.28 10.7 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF417 PAP_fibrillin PF04755.12 KXZ55274.1 - 7.6e-14 52.1 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin HVSL PF09749.9 KXZ55275.1 - 1.6e-28 99.8 0.0 2.2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KXZ55275.1 - 0.0062 16.4 0.3 0.16 11.8 0.1 2.2 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily Ank_4 PF13637.6 KXZ55277.1 - 5.8e-21 74.6 6.9 0.0014 19.2 0.1 6.7 6 0 0 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ55277.1 - 1.1e-20 74.0 0.8 2.9e-06 27.8 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ55277.1 - 8.8e-20 70.5 10.3 1.2e-06 28.6 0.0 6.8 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXZ55277.1 - 1.2e-18 66.7 11.0 0.00017 21.9 0.1 7.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 KXZ55277.1 - 5.3e-14 51.0 3.6 0.00043 20.5 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat SelR PF01641.18 KXZ55278.1 - 3.2e-46 156.3 0.0 4.2e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 SelR domain HECT_2 PF09814.9 KXZ55278.1 - 0.015 14.2 0.0 2.9 6.7 0.0 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HypA PF01155.19 KXZ55278.1 - 0.026 14.5 0.0 0.048 13.7 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 KXZ55278.1 - 0.22 11.5 2.8 0.23 11.4 0.2 2.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain SelR PF01641.18 KXZ55279.1 - 1.3e-16 60.8 0.0 1.4e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_SprT PF17283.2 KXZ55279.1 - 0.039 13.9 0.2 0.039 13.9 0.2 1.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Pkinase_Tyr PF07714.17 KXZ55280.1 - 1.1e-38 133.1 0.0 1e-33 116.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ55280.1 - 7.2e-31 107.5 0.0 1.4e-29 103.3 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Baculo_PEP_C PF04513.12 KXZ55282.1 - 0.018 15.1 8.5 1.1 9.3 2.2 3.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 KXZ55282.1 - 0.018 14.1 12.7 0.21 10.5 3.1 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Atg14 PF10186.9 KXZ55282.1 - 0.16 11.0 25.8 0.14 11.2 7.9 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KXZ55282.1 - 0.28 11.2 11.0 2.1 8.4 0.6 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KXZ55282.1 - 0.99 8.8 28.8 5.1 6.5 11.2 3.2 3 0 0 3 3 3 0 Golgin subfamily A member 5 EzrA PF06160.12 KXZ55282.1 - 1.7 6.7 15.4 0.42 8.7 4.8 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Baculo_p24 PF05073.12 KXZ55282.1 - 1.9 8.3 3.5 4.8 6.9 0.5 2.2 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Spc7 PF08317.11 KXZ55282.1 - 2 7.2 36.7 0.024 13.5 10.3 3.2 2 1 3 5 5 5 0 Spc7 kinetochore protein CtaG_Cox11 PF04442.14 KXZ55283.1 - 6e-56 188.7 0.5 7.1e-56 188.4 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 SET PF00856.28 KXZ55285.1 - 1.1e-10 42.2 0.0 1.8e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 SET domain PP2C PF00481.21 KXZ55286.1 - 1.1e-35 123.5 0.0 1.5e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3486 PF11985.8 KXZ55287.1 - 0.029 14.8 0.0 0.03 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) YEATS PF03366.16 KXZ55288.1 - 2.8e-11 43.2 0.0 4.1e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 YEATS family Imm49 PF15575.6 KXZ55289.1 - 0.024 14.4 3.1 0.026 14.3 3.1 1.1 1 0 0 1 1 1 0 Immunity protein 49 NAM-associated PF14303.6 KXZ55289.1 - 0.77 10.5 7.5 0.9 10.2 7.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TMA7 PF09072.10 KXZ55290.1 - 0.075 13.9 3.7 0.096 13.5 3.7 1.2 1 0 0 1 1 1 0 Translation machinery associated TMA7 AA_permease_2 PF13520.6 KXZ55291.1 - 1.2e-36 126.5 30.6 1.4e-36 126.2 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXZ55291.1 - 7.6e-25 87.4 28.7 1e-24 87.0 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 KXZ55291.1 - 0.044 12.6 9.0 0.13 11.1 9.0 1.7 1 1 0 1 1 1 0 Spore germination protein AA_permease_C PF13906.6 KXZ55292.1 - 1.6e-12 47.3 2.6 1.6e-12 47.3 2.6 2.6 3 0 0 3 3 3 1 C-terminus of AA_permease Glyco_transf_90 PF05686.12 KXZ55293.1 - 2.2e-20 72.9 0.1 2.5e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXZ55293.1 - 0.081 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Kinesin PF00225.23 KXZ55294.1 - 1.6e-73 247.5 0.0 3.6e-73 246.4 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ55294.1 - 4.7e-11 42.8 0.0 1.5e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 Microtubule binding CCDC144C PF14915.6 KXZ55294.1 - 7.3e-05 22.0 5.3 7.3e-05 22.0 5.3 2.6 3 0 0 3 3 3 2 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.9 KXZ55294.1 - 0.016 15.2 0.9 0.016 15.2 0.9 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KXZ55294.1 - 0.081 13.4 23.2 2 8.8 1.9 3.6 2 1 1 3 3 3 0 Fez1 MCC-bdg_PDZ PF10506.9 KXZ55294.1 - 0.31 11.1 10.5 0.076 13.0 5.1 2.6 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2353 PF09789.9 KXZ55294.1 - 1.2 8.4 17.9 9 5.6 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) CdvA PF18822.1 KXZ55294.1 - 5.6 6.8 8.6 1.6 8.5 3.7 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Lebercilin PF15619.6 KXZ55294.1 - 6.2 6.4 23.6 0.75 9.4 10.8 2.7 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 KXZ55294.1 - 6.7 4.1 22.9 5.7 4.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) UPF0184 PF03670.13 KXZ55294.1 - 7.9 6.9 7.7 3.8 7.9 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Ank_4 PF13637.6 KXZ55295.1 - 0.0025 18.3 0.1 0.33 11.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ55295.1 - 0.092 13.3 0.0 0.31 11.7 0.0 1.8 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Defensin_4 PF07936.12 KXZ55295.1 - 0.68 9.9 5.9 12 5.9 0.0 3.3 3 0 0 3 3 3 0 Potassium-channel blocking toxin Ank_2 PF12796.7 KXZ55296.1 - 2.9e-06 27.8 0.4 0.015 15.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ55296.1 - 1.2e-05 25.7 1.3 0.088 13.4 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55296.1 - 0.054 14.1 3.4 15 6.6 0.1 4.0 3 1 1 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 KXZ55296.1 - 0.19 12.1 2.2 51 4.4 0.0 3.6 2 2 2 4 4 4 0 Ankyrin repeats (many copies) AAA_12 PF13087.6 KXZ55297.1 - 4.3e-32 111.4 0.0 6.6e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXZ55297.1 - 3.3e-16 59.9 0.4 4.2e-07 30.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KXZ55297.1 - 1.2e-08 34.9 2.0 0.00015 21.6 0.2 3.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXZ55297.1 - 1.4e-06 28.7 1.7 0.0046 17.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 KXZ55297.1 - 0.00093 18.5 4.9 0.26 10.5 0.0 2.8 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXZ55297.1 - 0.00094 18.7 2.3 0.005 16.3 0.1 2.5 3 0 0 3 3 3 1 PhoH-like protein UvrD_C_2 PF13538.6 KXZ55297.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 KXZ55297.1 - 0.093 12.5 0.2 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2786 PF10979.8 KXZ55297.1 - 0.095 12.6 0.0 0.095 12.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) UvrD-helicase PF00580.21 KXZ55297.1 - 0.21 11.1 0.3 0.62 9.5 0.1 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TMEM132 PF16070.5 KXZ55299.1 - 1.9e-16 60.4 6.7 8.9e-16 58.2 6.9 2.0 2 1 0 2 2 2 1 Transmembrane protein family 132 fn3 PF00041.21 KXZ55300.1 - 0.0048 17.2 0.1 0.041 14.2 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KXZ55300.1 - 0.03 14.9 0.1 0.21 12.2 0.0 2.3 2 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Glyco_hydro_36C PF16874.5 KXZ55300.1 - 0.034 14.6 0.0 0.38 11.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 C-terminal domain Big_3_4 PF13754.6 KXZ55300.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.7 1 1 0 2 2 2 0 Domain of unknown function Alpha_kinase PF02816.18 KXZ55301.1 - 1.3e-23 84.1 0.0 1.2e-12 48.3 0.0 2.2 2 0 0 2 2 2 2 Alpha-kinase family VWA_2 PF13519.6 KXZ55301.1 - 1.4e-07 32.1 0.0 3.4e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXZ55301.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4585 PF15232.6 KXZ55301.1 - 0.037 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) vWA-TerF-like PF10138.9 KXZ55301.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus Alpha_kinase PF02816.18 KXZ55302.1 - 2.5e-39 135.3 0.0 4.8e-39 134.4 0.0 1.5 1 1 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KXZ55302.1 - 4.2e-07 30.6 0.0 1e-06 29.3 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KXZ55302.1 - 0.0042 17.4 0.0 0.0081 16.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KXZ55302.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF1824 PF08854.10 KXZ55302.1 - 0.21 11.5 0.0 0.51 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) Alpha_kinase PF02816.18 KXZ55303.1 - 7.1e-39 133.8 0.0 9.7e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KXZ55303.1 - 3.8e-07 30.7 0.0 1e-06 29.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXZ55303.1 - 0.22 11.8 0.0 0.56 10.4 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Alpha_kinase PF02816.18 KXZ55304.1 - 1.3e-38 133.0 0.0 2.2e-38 132.2 0.0 1.4 1 1 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KXZ55304.1 - 2.6e-05 24.8 0.0 6.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DJ-1_PfpI PF01965.24 KXZ55305.1 - 2.7e-42 144.4 0.1 3.1e-42 144.2 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Fumerase_C PF05683.12 KXZ55306.1 - 6.1e-91 303.3 0.0 9.1e-91 302.7 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 KXZ55306.1 - 3.9e-86 288.8 0.0 5e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Tmemb_14 PF03647.13 KXZ55307.1 - 4.7 8.0 10.7 7.1 7.4 10.2 1.6 1 1 0 1 1 1 0 Transmembrane proteins 14C Sec23_trunk PF04811.15 KXZ55308.1 - 7.8e-61 205.7 0.0 1.1e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KXZ55308.1 - 1.8e-19 70.3 0.0 5.7e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXZ55308.1 - 8.2e-16 57.8 3.0 1.5e-15 56.9 3.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 KXZ55308.1 - 3.5e-15 55.7 0.0 7.1e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KXZ55308.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Gelsolin repeat IRK_C PF17655.1 KXZ55309.1 - 1.1e-18 67.4 0.0 6e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KXZ55309.1 - 6.9e-06 25.9 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain WD40 PF00400.32 KXZ55310.1 - 0.0072 17.1 11.5 0.65 11.0 1.2 3.8 3 1 0 3 3 3 2 WD domain, G-beta repeat Mlh1_C PF16413.5 KXZ55311.1 - 1e-38 133.3 0.0 1.7e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KXZ55311.1 - 2e-24 85.5 0.0 3e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXZ55311.1 - 2.4e-11 43.6 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXZ55311.1 - 1.6e-06 28.5 0.0 3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fea1 PF07692.11 KXZ55311.1 - 0.85 8.6 3.1 1.3 7.9 3.1 1.2 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein Mlh1_C PF16413.5 KXZ55312.1 - 5.9e-17 61.9 0.3 6.2e-17 61.8 0.3 1.0 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus Pkinase PF00069.25 KXZ55313.1 - 1.4e-26 93.5 0.0 2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55313.1 - 5.8e-10 38.9 0.0 8.8e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ55313.1 - 6.2e-05 22.4 1.7 0.00041 19.7 1.7 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ55313.1 - 0.037 13.4 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ55313.1 - 0.042 13.8 1.9 0.068 13.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ55314.1 - 1.5e-50 172.1 0.0 2e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55314.1 - 7.8e-23 81.1 0.0 1.6e-21 76.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ55314.1 - 0.0023 17.3 0.3 0.0042 16.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ55314.1 - 0.029 14.3 0.1 0.029 14.3 0.1 3.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family Rotamase_2 PF13145.6 KXZ55314.1 - 0.081 13.8 4.9 0.051 14.4 2.0 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain HUN PF08729.10 KXZ55316.1 - 0.0003 20.7 3.3 0.00098 19.1 3.3 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain URO-D PF01208.17 KXZ55318.1 - 0.0056 15.9 0.1 0.0075 15.5 0.1 1.2 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Pkinase PF00069.25 KXZ55319.1 - 1.2e-21 77.3 0.0 5.5e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55319.1 - 4.4e-13 49.1 0.0 9.7e-11 41.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_transf_92 PF01697.27 KXZ55320.1 - 2.4e-07 30.7 0.6 3.6e-07 30.1 0.6 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KXZ55320.1 - 1.1e-05 25.9 0.4 1.7e-05 25.2 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 rve PF00665.26 KXZ55322.1 - 2.8e-06 27.5 0.0 4.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain SpoIIE PF07228.12 KXZ55325.1 - 3.1e-12 46.8 0.1 2.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXZ55325.1 - 4.1e-06 26.6 0.1 0.0056 16.3 0.2 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXZ55325.1 - 0.00016 21.4 3.4 0.0063 16.2 3.3 3.0 1 1 0 1 1 1 1 Protein phosphatase 2C RIX1 PF08167.12 KXZ55327.1 - 4e-14 52.8 0.0 7.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis EF-hand_7 PF13499.6 KXZ55328.1 - 2.9e-06 27.7 1.4 0.00031 21.1 1.4 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ55328.1 - 0.00023 20.9 2.3 1.2 9.2 0.1 3.7 4 0 0 4 4 3 2 EF-hand domain EF-hand_1 PF00036.32 KXZ55328.1 - 0.00023 20.5 0.4 0.43 10.2 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KXZ55328.1 - 0.0056 16.1 0.4 0.054 13.0 0.1 2.6 2 0 0 2 2 2 1 EF hand Filament PF00038.21 KXZ55328.1 - 0.0067 16.0 12.3 0.019 14.6 7.6 2.2 2 0 0 2 2 2 1 Intermediate filament protein FAM76 PF16046.5 KXZ55328.1 - 0.011 15.1 3.9 0.76 9.1 2.1 2.1 2 0 0 2 2 2 0 FAM76 protein EF-hand_8 PF13833.6 KXZ55328.1 - 0.032 14.1 1.7 15 5.6 0.8 3.2 2 1 0 2 2 2 0 EF-hand domain pair GOLGA2L5 PF15070.6 KXZ55328.1 - 0.036 12.7 12.3 0.085 11.5 10.7 1.9 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Baculo_PEP_C PF04513.12 KXZ55328.1 - 0.055 13.5 11.6 0.073 13.1 9.2 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KXZ55328.1 - 0.074 11.9 18.6 0.97 8.2 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KXZ55328.1 - 0.079 12.3 21.4 0.79 9.0 1.1 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CorA PF01544.18 KXZ55328.1 - 0.15 11.3 2.0 0.27 10.5 2.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF724 PF05266.14 KXZ55328.1 - 0.21 11.4 12.7 0.02 14.7 7.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KXZ55328.1 - 0.39 10.9 28.4 0.15 12.3 19.8 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SHE3 PF17078.5 KXZ55328.1 - 0.78 9.4 6.8 6.5 6.4 0.1 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 SPARC_Ca_bdg PF10591.9 KXZ55328.1 - 1.1 9.6 3.7 7.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region bZIP_1 PF00170.21 KXZ55328.1 - 2.2 8.4 7.9 8.8 6.5 0.2 2.8 3 0 0 3 3 3 0 bZIP transcription factor NPV_P10 PF05531.12 KXZ55328.1 - 3 8.4 9.0 1.5 9.3 2.0 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 KXZ55328.1 - 7.5 7.2 6.8 8.9 6.9 3.2 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HOOK PF05622.12 KXZ55328.1 - 8.6 4.4 14.1 0.26 9.4 7.7 1.6 2 0 0 2 2 2 0 HOOK protein FlxA PF14282.6 KXZ55328.1 - 9.2 6.3 26.8 12 6.0 20.2 2.7 2 1 0 2 2 2 0 FlxA-like protein DivIC PF04977.15 KXZ55328.1 - 9.9 6.0 24.1 1.6 8.5 5.4 3.4 2 1 1 3 3 3 0 Septum formation initiator Cornichon PF03311.14 KXZ55330.1 - 2.3e-28 99.0 1.1 2.9e-28 98.7 1.1 1.1 1 0 0 1 1 1 1 Cornichon protein Lipoprotein_19 PF13617.6 KXZ55331.1 - 0.74 9.6 2.1 1.6 8.6 2.1 1.5 1 0 0 1 1 1 0 YnbE-like lipoprotein Leu_leader PF08054.11 KXZ55335.1 - 0.68 9.6 3.4 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 Leucine operon leader peptide Pkinase PF00069.25 KXZ55337.1 - 4.2e-43 147.6 0.0 3.8e-30 105.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55337.1 - 1.1e-20 74.1 0.0 5.9e-18 65.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ55337.1 - 6.1e-05 23.1 0.0 0.064 13.2 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KXZ55337.1 - 0.00064 19.1 0.1 0.0019 17.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ55337.1 - 0.0082 15.5 0.0 0.025 13.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXZ55337.1 - 0.069 11.9 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinesin PF00225.23 KXZ55340.1 - 1.4e-94 316.7 0.0 1.9e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ55340.1 - 2e-25 89.5 0.1 5.2e-25 88.1 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding GRP PF07172.11 KXZ55340.1 - 0.0026 18.4 13.0 0.0026 18.4 13.0 4.7 4 0 0 4 4 4 1 Glycine rich protein family DUF641 PF04859.12 KXZ55340.1 - 9.1 6.6 6.8 12 6.2 0.4 2.9 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) PmbA_TldD PF01523.16 KXZ55341.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF4775 PF16001.5 KXZ55341.1 - 1.9 7.8 7.8 3.2 7.1 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Voltage_CLC PF00654.20 KXZ55344.1 - 1.8e-51 175.5 33.5 1.8e-51 175.5 33.5 2.4 2 1 0 2 2 2 1 Voltage gated chloride channel zf-MYND PF01753.18 KXZ55345.1 - 1.4e-14 53.8 22.0 4.7e-08 33.0 7.2 2.5 2 0 0 2 2 2 2 MYND finger TFIIA PF03153.13 KXZ55345.1 - 4.2 7.3 16.5 5.4 6.9 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SBP PF03110.14 KXZ55347.1 - 4.9e-14 52.4 6.0 8.6e-14 51.6 6.0 1.4 1 0 0 1 1 1 1 SBP domain SufE PF02657.15 KXZ55348.1 - 8.3e-26 90.2 0.0 1.3e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain NadA PF02445.16 KXZ55348.1 - 1e-06 28.1 0.1 1.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Quinolinate synthetase A protein EccE PF11203.8 KXZ55348.1 - 1.8 9.0 7.0 2.1 8.7 0.2 3.5 1 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Cupin_6 PF12852.7 KXZ55349.1 - 0.0094 15.7 1.3 0.021 14.5 0.6 1.9 1 1 1 2 2 2 1 Cupin EptA_B_N PF08019.12 KXZ55349.1 - 0.29 11.0 5.1 1.4 8.8 1.6 2.4 2 1 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB NadA PF02445.16 KXZ55350.1 - 0.16 11.1 0.0 13 4.8 0.0 2.1 2 0 0 2 2 2 0 Quinolinate synthetase A protein cobW PF02492.19 KXZ55351.1 - 4.7e-51 172.9 0.6 9.7e-38 129.5 0.3 2.1 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ55351.1 - 3.3e-19 68.6 0.1 8.2e-15 54.5 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KXZ55351.1 - 0.00093 19.1 0.1 0.7 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXZ55351.1 - 0.0013 19.2 0.1 0.0028 18.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KXZ55351.1 - 0.0022 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein GTP_EFTU PF00009.27 KXZ55351.1 - 0.0037 16.8 0.0 0.45 10.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KXZ55351.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KXZ55351.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 KXZ55351.1 - 0.035 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXZ55351.1 - 0.045 14.3 0.0 0.096 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXZ55351.1 - 0.054 12.7 0.1 1.1 8.3 0.0 2.4 2 1 1 3 3 3 0 NB-ARC domain MobB PF03205.14 KXZ55351.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pkinase PF00069.25 KXZ55352.1 - 3.4e-45 154.5 0.0 5.7e-26 91.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55352.1 - 2.3e-20 73.0 0.0 7.3e-14 51.7 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ55352.1 - 1.1e-05 24.4 0.0 2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ55352.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ55352.1 - 0.0037 16.6 0.0 0.01 15.2 0.1 1.6 2 0 0 2 2 2 1 Kinase-like Cation_ATPase_C PF00689.21 KXZ55354.1 - 1.9e-34 119.0 7.1 5.6e-22 78.3 0.2 2.9 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXZ55354.1 - 7.2e-34 116.9 1.0 7.2e-34 116.9 1.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXZ55354.1 - 1.1e-18 68.3 3.3 5.2e-17 62.8 3.3 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ55354.1 - 7.7e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXZ55354.1 - 2.3e-09 36.8 0.4 2.6e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXZ55354.1 - 1.6e-05 24.8 0.2 5.5e-05 23.0 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KXZ55355.1 - 2.9e-38 131.3 0.2 3.8e-38 130.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ55355.1 - 4.4e-28 98.4 0.3 5.3e-28 98.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ55355.1 - 3.9e-06 26.9 0.1 5.4e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KXZ55356.1 - 0.00027 21.6 0.0 0.00052 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ55356.1 - 0.005 17.6 0.0 0.0079 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ55356.1 - 0.0094 16.6 0.0 0.019 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ55356.1 - 0.023 14.5 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.21 KXZ55357.1 - 1.8e-58 198.5 0.0 2.2e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXZ55357.1 - 5.7e-09 35.7 0.1 7.8e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXZ55357.1 - 6.4e-07 28.7 0.0 8.5e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXZ55357.1 - 1.4e-06 27.1 0.0 2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXZ55357.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase zf-RING_2 PF13639.6 KXZ55358.1 - 6.4e-06 26.4 3.2 1.1e-05 25.6 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXZ55358.1 - 2.4e-05 24.5 3.8 4.9e-05 23.5 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXZ55358.1 - 6.7e-05 22.7 1.0 0.00012 21.9 1.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXZ55358.1 - 9.7e-05 22.2 2.7 0.00018 21.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ55358.1 - 0.00033 20.6 2.5 0.00056 19.8 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXZ55358.1 - 0.00093 19.2 0.5 0.0018 18.3 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXZ55358.1 - 0.0014 18.7 3.8 0.0026 17.9 3.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KXZ55358.1 - 0.0028 17.5 2.3 0.0052 16.6 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ55358.1 - 0.0051 16.8 3.0 0.0051 16.8 3.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXZ55358.1 - 0.15 11.9 7.0 0.46 10.4 7.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXZ55358.1 - 0.43 10.4 2.0 0.78 9.6 2.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4619 PF15398.6 KXZ55359.1 - 5.7 6.4 22.2 0.79 9.2 15.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4619) DUF4191 PF13829.6 KXZ55360.1 - 0.31 10.4 3.8 0.43 9.9 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Phage_holin_3_6 PF07332.11 KXZ55360.1 - 4.5 7.4 11.0 10 6.2 11.0 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pro_dh PF01619.18 KXZ55361.1 - 1.4e-71 241.5 0.2 3e-70 237.1 0.2 2.2 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_7 PF13499.6 KXZ55361.1 - 8.6e-07 29.3 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ55361.1 - 3.5e-05 23.1 0.1 7e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ55361.1 - 0.00014 21.5 0.1 0.00045 19.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KXZ55361.1 - 0.00028 20.2 0.0 0.00057 19.3 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXZ55361.1 - 0.0029 17.4 0.1 0.0076 16.1 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair Fimbrial_PilY2 PF14481.6 KXZ55362.1 - 0.099 12.3 0.0 0.26 11.0 0.0 1.7 2 1 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 HEAT_EZ PF13513.6 KXZ55363.1 - 1.4e-13 51.0 8.7 6.1e-08 33.0 0.1 7.7 7 1 1 8 8 7 1 HEAT-like repeat HEAT PF02985.22 KXZ55363.1 - 4.2e-13 48.3 17.7 0.00041 20.4 0.0 10.8 13 0 0 13 13 11 3 HEAT repeat IBN_N PF03810.19 KXZ55363.1 - 2.5e-12 46.5 0.2 1.6e-09 37.5 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KXZ55363.1 - 1.7e-09 37.9 7.5 0.00089 19.6 0.0 7.8 4 2 4 9 9 8 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KXZ55363.1 - 2.3e-07 31.3 0.7 0.0035 17.9 0.3 5.8 7 1 0 7 7 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXZ55363.1 - 4.2e-06 26.9 0.5 0.3 11.1 0.0 4.2 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 KXZ55363.1 - 2.6e-05 24.1 1.3 0.032 14.0 0.1 4.3 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) MMS19_N PF14500.6 KXZ55363.1 - 0.00069 19.3 0.2 0.0063 16.1 0.1 2.5 2 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 KXZ55363.1 - 0.001 19.0 4.1 0.85 9.8 0.1 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF1981 PF09324.10 KXZ55363.1 - 0.025 14.4 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) CLASP_N PF12348.8 KXZ55363.1 - 0.09 12.3 2.2 4.3 6.8 0.0 3.7 3 1 1 4 4 4 0 CLASP N terminal DUF1041 PF06292.17 KXZ55363.1 - 0.091 13.2 1.6 5.6 7.4 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) RNase_P_pop3 PF08228.11 KXZ55363.1 - 0.12 12.5 0.2 0.36 10.9 0.1 1.8 2 0 0 2 2 2 0 RNase P subunit Pop3 HEAT_PBS PF03130.16 KXZ55363.1 - 0.2 12.4 5.0 3 8.8 0.0 5.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Na_H_Exchanger PF00999.21 KXZ55365.1 - 1e-30 106.8 37.9 1e-30 106.8 37.9 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family SEP PF08059.13 KXZ55366.1 - 3.5e-21 75.5 0.3 1.1e-20 74.0 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KXZ55366.1 - 1.9e-19 69.6 0.0 4.7e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 UBX domain Glucosamine_iso PF01182.20 KXZ55367.1 - 7.6e-63 212.4 0.0 1e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase zf-RanBP PF00641.18 KXZ55368.1 - 0.14 11.5 1.1 0.2 11.0 1.1 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-RanBP PF00641.18 KXZ55369.1 - 2.5e-05 23.5 11.1 0.0011 18.2 3.0 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KXZ55369.1 - 0.075 13.1 2.7 0.23 11.5 2.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KXZ55369.1 - 0.8 9.2 3.0 23 4.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Methyltransf_25 PF13649.6 KXZ55370.1 - 1.1e-16 61.3 0.0 2.6e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ55370.1 - 2.7e-16 60.0 0.0 5.1e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ55370.1 - 1.2e-11 45.2 0.0 2.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ55370.1 - 4e-10 39.8 0.0 6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ55370.1 - 2e-09 37.5 0.0 3.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ55370.1 - 1.4e-08 34.4 0.0 2.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXZ55370.1 - 2.2e-06 27.1 0.0 3.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KXZ55370.1 - 1.6e-05 24.5 0.0 6.7e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KXZ55370.1 - 3.4e-05 24.8 0.0 6.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXZ55370.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 KXZ55370.1 - 0.036 14.2 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase HydF_tetramer PF18133.1 KXZ55371.1 - 8.1e-33 112.7 0.0 2e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 Hydrogen maturase F tetramerization domain MMR_HSR1 PF01926.23 KXZ55371.1 - 7.4e-17 61.5 0.1 1.6e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Radical_SAM PF04055.21 KXZ55371.1 - 2.3e-16 60.6 0.0 6.1e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily HydF_dimer PF18128.1 KXZ55371.1 - 4.2e-09 36.4 0.1 0.0036 17.4 0.0 3.1 3 0 0 3 3 3 2 Hydrogen maturase F dimerization domain Dynamin_N PF00350.23 KXZ55371.1 - 3e-05 24.1 0.1 0.0001 22.4 0.1 1.7 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KXZ55371.1 - 6.6e-05 22.5 0.1 0.00012 21.7 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXZ55371.1 - 0.00015 21.3 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KXZ55371.1 - 0.011 16.3 0.1 0.03 14.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Virul_Fac PF10139.9 KXZ55371.1 - 0.096 10.9 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor CRAL_TRIO PF00650.20 KXZ55372.1 - 1e-25 90.3 0.0 1.4e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXZ55372.1 - 0.04 14.1 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain RNase_T PF00929.24 KXZ55373.1 - 1.4e-24 87.5 0.0 1.9e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease zf-GRF PF06839.12 KXZ55373.1 - 2e-10 40.6 2.0 3.7e-10 39.7 2.0 1.5 1 0 0 1 1 1 1 GRF zinc finger HicB_lk_antitox PF15919.5 KXZ55376.1 - 0.032 14.4 0.1 0.045 13.9 0.1 1.3 1 1 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system PolyA_pol_RNAbd PF12627.7 KXZ55376.1 - 0.16 11.7 0.2 15 5.4 0.1 2.3 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Fur_reg_FbpA PF13076.6 KXZ55376.1 - 0.25 11.1 1.1 1.8 8.3 0.8 2.2 2 0 0 2 2 2 0 Fur-regulated basic protein A BUD22 PF09073.10 KXZ55379.1 - 9.6e-26 91.1 77.9 7.4e-08 32.1 0.1 5.1 3 1 0 3 3 3 3 BUD22 Myb_DNA-binding PF00249.31 KXZ55380.1 - 2.9e-20 72.2 2.5 1.1e-13 51.1 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ55380.1 - 4.5e-16 58.8 2.0 2.3e-09 37.3 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Ank_2 PF12796.7 KXZ55381.1 - 7.7e-19 68.1 3.5 0.00092 19.8 0.0 7.8 8 1 0 8 8 8 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ55381.1 - 1.8e-14 53.9 2.1 0.0041 17.7 0.1 7.5 7 1 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55381.1 - 5.2e-12 44.8 16.5 0.75 10.6 0.0 12.0 14 0 0 14 14 14 2 Ankyrin repeat Ank_5 PF13857.6 KXZ55381.1 - 0.00014 22.1 15.4 0.17 12.2 0.8 6.9 8 0 0 8 8 8 2 Ankyrin repeats (many copies) SSI PF00720.17 KXZ55381.1 - 0.01 15.8 0.5 0.072 13.0 0.0 2.8 2 0 0 2 2 2 0 Subtilisin inhibitor-like Ank PF00023.30 KXZ55381.1 - 0.1 13.1 22.7 2 9.0 0.1 8.9 10 0 0 10 10 10 0 Ankyrin repeat ApoO PF09769.9 KXZ55381.1 - 3.3 7.7 7.1 0.32 10.9 0.4 2.6 2 1 1 3 3 3 0 Apolipoprotein O SBP PF03110.14 KXZ55382.1 - 0.00012 22.3 2.4 0.00025 21.3 2.4 1.4 1 0 0 1 1 1 1 SBP domain CRAL_TRIO PF00650.20 KXZ55383.1 - 1.3e-25 90.0 0.0 1.8e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain PHD PF00628.29 KXZ55384.1 - 1.4e-09 37.7 0.2 3.2e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 PHD-finger rve PF00665.26 KXZ55384.1 - 2.5e-08 34.1 0.0 6.7e-08 32.7 0.0 1.7 1 1 1 2 2 2 1 Integrase core domain rve_3 PF13683.6 KXZ55384.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Glyco_tranf_2_3 PF13641.6 KXZ55386.1 - 0.00017 21.6 0.5 0.0003 20.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXZ55386.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.27 KXZ55387.1 - 5.7e-46 156.4 0.4 1.6e-21 77.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KXZ55387.1 - 2.9e-16 60.2 8.0 0.0031 17.4 0.1 5.1 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ55387.1 - 2.4e-11 43.5 0.7 0.018 14.5 0.1 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXZ55387.1 - 1.1e-06 28.7 0.2 0.0029 17.7 0.0 3.5 2 1 1 3 3 3 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXZ55387.1 - 1.1e-06 29.0 0.1 0.04 14.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KXZ55387.1 - 3.1e-06 27.2 0.5 0.035 14.0 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KXZ55387.1 - 5.6e-06 26.0 0.4 0.086 12.6 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ55387.1 - 1.6e-05 25.4 2.4 0.071 13.5 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KXZ55387.1 - 2.6e-05 24.4 0.0 0.059 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXZ55387.1 - 5.5e-05 23.4 0.0 0.41 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KXZ55387.1 - 6.1e-05 23.4 0.0 0.76 10.2 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXZ55387.1 - 0.00026 20.8 0.0 0.23 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KXZ55387.1 - 0.0005 20.6 0.0 0.0038 17.8 0.0 5.1 6 0 0 6 6 4 2 AAA domain RNA_helicase PF00910.22 KXZ55387.1 - 0.00059 20.2 0.0 0.46 10.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ABC_tran_Xtn PF12848.7 KXZ55387.1 - 0.00059 19.8 5.9 0.00059 19.8 5.9 4.5 4 1 0 4 4 2 1 ABC transporter cobW PF02492.19 KXZ55387.1 - 0.0022 17.6 0.2 1.3 8.6 0.0 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXZ55387.1 - 0.0027 17.4 1.2 0.65 9.7 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KXZ55387.1 - 0.0036 16.9 0.7 1.7 8.2 0.0 3.6 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 KXZ55387.1 - 0.0044 16.9 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KXZ55387.1 - 0.01 15.9 0.0 8.4 6.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF3584 PF12128.8 KXZ55387.1 - 0.013 13.0 0.2 0.013 13.0 0.2 4.8 5 0 0 5 5 4 0 Protein of unknown function (DUF3584) NB-ARC PF00931.22 KXZ55387.1 - 0.018 14.2 0.1 2.8 7.1 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 KXZ55387.1 - 0.019 15.0 0.1 5.6 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXZ55387.1 - 0.021 15.4 8.0 1.2 9.7 0.0 4.5 5 0 0 5 5 4 0 AAA domain SRP54 PF00448.22 KXZ55387.1 - 0.051 13.2 0.0 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KXZ55387.1 - 0.064 12.8 0.2 2.9 7.4 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KXZ55387.1 - 0.072 13.3 0.4 4.3 7.6 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KXZ55387.1 - 0.082 12.6 0.0 14 5.3 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 KXZ55387.1 - 0.1 12.6 0.2 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KXZ55387.1 - 0.21 11.6 10.5 2.6 8.1 0.0 4.3 3 1 1 4 4 4 0 Dynamin family DDHD PF02862.17 KXZ55387.1 - 0.24 11.5 6.9 6.9 6.8 4.7 2.4 2 0 0 2 2 2 0 DDHD domain AAA_15 PF13175.6 KXZ55387.1 - 0.83 9.3 27.3 1.5 8.5 0.2 4.8 5 0 0 5 5 4 0 AAA ATPase domain AAA_13 PF13166.6 KXZ55387.1 - 1.1 7.8 0.0 1.1 7.8 0.0 4.4 6 0 0 6 6 5 0 AAA domain DUF2151 PF10221.9 KXZ55387.1 - 4.9 5.6 17.0 7.3 5.1 14.7 2.2 3 0 0 3 3 3 0 Cell cycle and development regulator WD40 PF00400.32 KXZ55388.1 - 1.6e-16 60.3 10.6 0.0016 19.2 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55388.1 - 5.5e-09 36.2 0.1 0.00029 21.1 0.2 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KXZ55388.1 - 0.032 13.1 0.1 0.063 12.2 0.1 1.5 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 KXZ55388.1 - 0.048 13.5 0.0 2.2 8.1 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXZ55388.1 - 0.13 10.9 0.1 3.9 6.0 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Sigma70_ner PF04546.13 KXZ55388.1 - 9.8 6.0 7.0 1.3 8.8 2.9 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Guanylate_cyc PF00211.20 KXZ55389.1 - 1e-07 31.7 0.0 5.7e-06 26.1 0.0 3.2 3 1 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain SBP_bac_8 PF13416.6 KXZ55389.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF2405 PF10293.9 KXZ55389.1 - 0.13 12.2 0.0 24 4.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2405) DUF3110 PF11360.8 KXZ55389.1 - 0.17 12.1 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) LapA_dom PF06305.11 KXZ55389.1 - 0.18 11.7 1.6 0.5 10.2 1.6 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EF-hand_7 PF13499.6 KXZ55390.1 - 0.0059 17.0 0.1 0.082 13.4 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair DUF5586 PF17824.1 KXZ55390.1 - 0.023 13.8 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) EF-hand_8 PF13833.6 KXZ55390.1 - 0.047 13.5 0.7 0.3 11.0 0.0 2.3 2 1 1 3 3 3 0 EF-hand domain pair DUF5582 PF17819.1 KXZ55390.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) Cytochrom_B559 PF00283.19 KXZ55390.1 - 0.25 10.8 0.1 0.42 10.1 0.1 1.4 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits WD40 PF00400.32 KXZ55391.1 - 1.7e-24 85.6 15.6 0.0003 21.5 0.2 11.6 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55391.1 - 1.5e-08 34.8 0.0 9.6 6.6 0.0 7.0 3 3 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXZ55391.1 - 6.6e-07 29.2 4.1 0.015 14.9 0.1 2.9 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KXZ55391.1 - 0.17 11.9 0.6 21 5.3 0.1 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat ANAPC5 PF12862.7 KXZ55392.1 - 4.3e-14 52.3 0.0 1.2e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 zf-CCCH PF00642.24 KXZ55393.1 - 1.6e-09 37.4 5.8 2.8e-09 36.6 5.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXZ55393.1 - 9.4e-07 28.5 2.9 1.6e-06 27.7 2.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXZ55393.1 - 6.1e-06 26.1 3.4 1.1e-05 25.3 3.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 KXZ55393.1 - 0.0027 18.1 2.2 0.0056 17.1 2.2 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KXZ55393.1 - 0.046 14.4 0.8 0.046 14.4 0.8 1.6 2 0 0 2 2 2 0 Torus domain CRAL_TRIO PF00650.20 KXZ55394.1 - 1.7e-26 92.8 0.0 2.3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXZ55394.1 - 0.00017 21.8 0.0 0.00023 21.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2087 PF09860.9 KXZ55394.1 - 0.11 12.7 0.0 0.94 9.7 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) AIRC PF00731.20 KXZ55395.1 - 1.8e-08 34.1 12.8 1.8e-08 34.1 12.8 2.2 2 1 1 3 3 3 1 AIR carboxylase MscS_porin PF12795.7 KXZ55396.1 - 0.0083 15.7 5.3 0.011 15.3 5.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF737 PF05300.11 KXZ55396.1 - 0.012 16.0 4.2 0.016 15.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF3693 PF12472.8 KXZ55396.1 - 0.025 14.3 1.7 0.074 12.7 0.6 2.3 2 0 0 2 2 2 0 Phage related protein Spc7 PF08317.11 KXZ55396.1 - 0.027 13.4 1.1 0.034 13.0 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-Q PF13094.6 KXZ55396.1 - 0.1 12.8 3.1 0.16 12.1 3.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NAM-associated PF14303.6 KXZ55396.1 - 0.23 12.1 6.4 0.49 11.1 6.4 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Ndc1_Nup PF09531.10 KXZ55396.1 - 2 7.0 6.7 2.2 6.9 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 KXZ55396.1 - 2.1 8.2 5.1 2.4 8.0 5.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ERM PF00769.19 KXZ55396.1 - 9.3 6.0 11.9 16 5.3 11.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RAP1 PF07218.11 KXZ55396.1 - 9.9 4.3 8.1 10 4.2 8.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IFT20 PF14931.6 KXZ55397.1 - 0.042 14.0 0.3 0.055 13.6 0.3 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 KI67R PF08065.12 KXZ55397.1 - 0.062 13.8 0.3 0.077 13.6 0.3 1.3 1 0 0 1 1 1 0 KI67R (NUC007) repeat DUF948 PF06103.11 KXZ55397.1 - 0.66 10.3 3.9 1.3 9.4 3.9 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ank_4 PF13637.6 KXZ55398.1 - 5e-11 42.9 5.8 0.026 15.1 0.0 6.3 4 1 4 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ55398.1 - 2.9e-10 40.6 0.2 0.012 16.2 0.2 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ55398.1 - 0.00017 21.8 3.4 34 5.5 0.0 7.1 8 0 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 KXZ55398.1 - 0.0031 17.8 7.4 8.4 6.8 0.0 6.0 3 2 4 7 7 7 2 Ankyrin repeats (many copies) F-box PF00646.33 KXZ55398.1 - 0.019 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 F-box domain SpoIIID PF12116.8 KXZ55398.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D Defensin_4 PF07936.12 KXZ55398.1 - 4 7.4 5.6 18 5.3 0.2 3.3 3 0 0 3 3 3 0 Potassium-channel blocking toxin RT_RNaseH PF17917.1 KXZ55399.1 - 1.5e-23 83.1 0.0 1.6e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KXZ55399.1 - 1.1e-14 54.3 0.0 1.7e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PLL PF18587.1 KXZ55399.1 - 0.052 13.7 0.0 0.084 13.0 0.0 1.4 1 1 0 1 1 1 0 PTX/LNS-Like (PLL) domain RT_RNaseH_2 PF17919.1 KXZ55400.1 - 8.6e-35 118.8 0.0 1.2e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXZ55400.1 - 1.1e-31 109.2 0.0 1.6e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LCM PF04072.14 KXZ55401.1 - 1.2e-24 87.3 0.0 1.6e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LEM PF03020.15 KXZ55401.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 LEM domain ALS_ss_C PF10369.9 KXZ55405.1 - 4.8e-54 180.5 0.2 9.4e-27 93.0 0.0 3.3 3 0 0 3 3 3 2 Small subunit of acetolactate synthase ACT PF01842.25 KXZ55405.1 - 1.5e-15 56.6 3.2 1.8e-11 43.6 0.5 3.4 4 0 0 4 4 4 2 ACT domain ACT_5 PF13710.6 KXZ55405.1 - 5.7e-09 35.7 0.1 5.4e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 KXZ55405.1 - 2e-05 24.5 1.0 0.0013 18.7 0.2 3.7 4 1 0 4 4 4 1 ACT domain ACT_4 PF13291.6 KXZ55405.1 - 3.5e-05 24.3 0.6 0.0029 18.1 0.3 2.6 2 0 0 2 2 2 1 ACT domain NikR_C PF08753.11 KXZ55405.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 NikR C terminal nickel binding domain DNApol3-delta_C PF09115.10 KXZ55405.1 - 0.21 12.1 0.4 15 6.1 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal YbbR PF07949.12 KXZ55405.1 - 2.8 8.3 6.8 0.69 10.3 0.3 3.0 4 0 0 4 4 4 0 YbbR-like protein Siva PF05458.12 KXZ55406.1 - 5e-06 26.3 9.3 6.9e-06 25.8 9.3 1.2 1 0 0 1 1 1 1 Cd27 binding protein (Siva) zf-CRD PF17979.1 KXZ55406.1 - 0.013 15.6 5.7 0.02 15.0 5.7 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Ephrin_rec_like PF07699.13 KXZ55406.1 - 0.045 13.5 0.1 0.045 13.5 0.1 2.4 1 1 1 2 2 2 0 Putative ephrin-receptor like FYVE_2 PF02318.16 KXZ55406.1 - 0.05 13.8 5.1 0.071 13.3 5.1 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger MS_channel PF00924.18 KXZ55407.1 - 7.1e-32 110.6 2.5 1.3e-31 109.8 2.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel Gal_GalNac_35kD PF17337.2 KXZ55407.1 - 0.00048 20.2 0.5 0.00077 19.6 0.5 1.2 1 0 0 1 1 1 1 Galactose-inhibitable lectin 35 kDa subunit BATS PF06968.13 KXZ55408.1 - 5.6e-25 87.3 0.0 1.3e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KXZ55408.1 - 1e-05 26.0 0.0 3.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KXZ55408.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain EF-hand_7 PF13499.6 KXZ55409.1 - 8.3e-13 48.6 0.0 2.6e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ55409.1 - 3.3e-12 45.0 0.0 4.3e-06 25.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXZ55409.1 - 5.4e-10 38.4 0.0 3e-06 26.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KXZ55409.1 - 2.9e-08 32.8 0.0 6.3e-05 22.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXZ55409.1 - 3.3e-05 23.7 0.2 0.0007 19.4 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 KXZ55409.1 - 0.025 14.5 0.1 3.1 7.8 0.0 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3138 PF11336.8 KXZ55409.1 - 2.3 6.8 4.3 3.6 6.1 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) WD40 PF00400.32 KXZ55410.1 - 4.1e-13 49.6 0.9 0.37 11.7 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Peptidase_M41 PF01434.18 KXZ55411.1 - 0.0092 15.8 1.3 0.072 12.9 1.3 2.2 1 1 0 1 1 1 1 Peptidase family M41 Ntox14 PF15522.6 KXZ55411.1 - 0.035 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Novel toxin 14 Peptidase_M50B PF13398.6 KXZ55411.1 - 0.043 13.4 1.7 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase M50B-like DIM1 PF02966.16 KXZ55412.1 - 2.2e-66 221.7 0.1 2.5e-66 221.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KXZ55412.1 - 3e-06 27.1 0.0 3.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXZ55412.1 - 0.0052 17.1 0.1 0.0089 16.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXZ55412.1 - 0.074 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like AMP-binding PF00501.28 KXZ55413.1 - 1.5e-96 323.6 0.0 1.8e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ55413.1 - 1.9e-23 83.2 0.1 3.7e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXZ55413.1 - 3.8e-22 78.0 1.8 9e-22 76.8 1.8 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Pyr_redox_2 PF07992.14 KXZ55415.1 - 1.6e-48 165.5 0.1 2.3e-48 164.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ55415.1 - 1.7e-19 70.2 0.0 4.9e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 KXZ55415.1 - 6.7e-17 61.4 0.0 1.3e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.27 KXZ55415.1 - 1.6e-14 54.2 0.9 6.7e-12 45.8 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ55415.1 - 3.2e-06 26.1 0.4 0.01 14.6 0.1 2.9 2 1 1 3 3 3 2 HI0933-like protein GIDA PF01134.22 KXZ55415.1 - 7.4e-06 25.3 2.0 0.0069 15.5 0.0 4.0 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXZ55415.1 - 1.7e-05 24.1 2.6 0.00039 19.6 0.1 3.1 2 1 1 3 3 3 1 FAD binding domain Glutaredoxin PF00462.24 KXZ55415.1 - 2.3e-05 24.5 0.2 0.0001 22.5 0.1 2.2 2 0 0 2 2 1 1 Glutaredoxin FAD_oxidored PF12831.7 KXZ55415.1 - 2.4e-05 23.9 0.0 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXZ55415.1 - 0.00016 20.9 0.3 0.0047 16.1 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXZ55415.1 - 0.00017 20.9 0.1 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Thioredoxin_3 PF13192.6 KXZ55415.1 - 0.00018 21.4 0.1 0.0011 19.0 0.2 2.2 2 0 0 2 2 2 1 Thioredoxin domain DAO PF01266.24 KXZ55415.1 - 0.00025 20.8 1.0 0.47 10.0 0.1 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXZ55415.1 - 0.00057 20.1 3.7 0.002 18.3 0.0 3.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thioredoxin_2 PF13098.6 KXZ55415.1 - 0.0011 19.4 0.4 0.0082 16.6 0.3 2.5 2 1 0 2 2 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 KXZ55415.1 - 0.017 15.3 0.4 0.35 11.0 0.2 2.3 1 1 1 2 2 2 0 Thioredoxin NAD_binding_7 PF13241.6 KXZ55415.1 - 0.021 15.2 0.1 0.99 9.9 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Thioredoxin_7 PF13899.6 KXZ55415.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like MCLC PF05934.11 KXZ55415.1 - 0.074 11.8 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) TraF PF13728.6 KXZ55415.1 - 0.093 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Trp_halogenase PF04820.14 KXZ55415.1 - 0.15 10.9 0.9 0.33 9.8 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase DUF836 PF05768.14 KXZ55415.1 - 0.23 11.9 0.1 0.94 9.9 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) LRR_8 PF13855.6 KXZ55416.1 - 6.1e-59 195.7 30.7 3.4e-12 45.9 1.5 9.0 5 3 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KXZ55416.1 - 5e-42 141.2 43.8 9.1e-06 25.9 0.1 10.7 7 3 4 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ55416.1 - 6.8e-15 53.3 40.0 0.21 12.3 0.2 14.6 15 0 0 15 15 15 6 Leucine Rich Repeat LRR_6 PF13516.6 KXZ55416.1 - 1.2e-10 40.6 36.7 1.9 8.8 0.3 12.4 13 0 0 13 13 13 7 Leucine Rich repeat LRR_9 PF14580.6 KXZ55416.1 - 1.2e-06 28.1 7.9 0.71 9.3 0.2 6.1 4 2 3 7 7 7 5 Leucine-rich repeat PAS_9 PF13426.7 KXZ55417.1 - 0.0002 21.6 0.0 0.029 14.6 0.0 3.8 4 0 0 4 4 4 1 PAS domain PAS PF00989.25 KXZ55417.1 - 0.00023 21.1 0.0 13 5.8 0.0 4.2 5 0 0 5 5 5 3 PAS fold PAS_8 PF13188.7 KXZ55417.1 - 0.012 15.6 0.0 0.079 13.0 0.0 2.5 2 0 0 2 2 2 0 PAS domain P22_AR_C PF10548.9 KXZ55417.1 - 0.2 11.8 0.0 0.52 10.5 0.0 1.6 1 0 0 1 1 1 0 P22AR C-terminal domain PTA_PTB PF01515.19 KXZ55418.1 - 3.8e-115 384.6 3.1 5e-115 384.2 3.1 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 KXZ55418.1 - 3.2e-16 59.8 0.0 6.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 KXZ55418.1 - 2.2e-09 37.1 0.7 4.5e-07 29.6 0.1 3.2 3 0 0 3 3 3 2 DRTGG domain DUF4303 PF14136.6 KXZ55418.1 - 0.0039 16.9 0.0 4.2 7.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4303) PAS PF00989.25 KXZ55419.1 - 3.8e-07 30.1 0.0 0.38 10.8 0.0 4.8 6 0 0 6 6 6 3 PAS fold PAS_9 PF13426.7 KXZ55419.1 - 0.00019 21.6 0.0 0.92 9.8 0.0 3.8 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KXZ55419.1 - 0.00053 20.2 0.5 1.8 8.9 0.0 5.1 6 0 0 6 6 6 1 PAS fold TPR_6 PF13174.6 KXZ55421.1 - 0.024 15.2 0.1 1.5 9.6 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TOBE_2 PF08402.10 KXZ55422.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 TOBE domain Peptidase_C48 PF02902.19 KXZ55423.1 - 1.5e-07 31.5 0.0 1.5e-05 25.0 0.0 2.9 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain PTPlike_phytase PF14566.6 KXZ55424.1 - 3.3e-124 410.6 0.0 5.4e-52 176.0 0.0 4.3 4 0 0 4 4 4 4 Inositol hexakisphosphate DUF4880 PF16220.5 KXZ55424.1 - 2.9 7.8 5.2 4.5 7.2 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) DUF2722 PF10846.8 KXZ55425.1 - 0.0042 16.1 9.1 0.0042 16.1 9.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 KXZ55425.1 - 0.0087 16.7 4.2 0.0087 16.7 4.2 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 KXZ55425.1 - 0.29 9.9 2.8 0.13 11.0 0.6 1.5 2 0 0 2 2 2 0 Presenilin HD-ZIP_N PF04618.12 KXZ55425.1 - 0.35 11.4 2.5 0.89 10.1 2.5 1.7 1 0 0 1 1 1 0 HD-ZIP protein N terminus TMEM51 PF15345.6 KXZ55425.1 - 0.39 10.5 8.2 0.074 12.9 3.6 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 AXIN1_TNKS_BD PF16646.5 KXZ55425.1 - 0.5 11.3 0.1 0.5 11.3 0.1 3.0 3 0 0 3 3 3 0 Axin-1 tankyrase binding domain EIIBC-GUT_N PF03612.14 KXZ55425.1 - 0.57 9.9 3.9 1.2 8.8 3.9 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 KXZ55425.1 - 0.6 10.1 25.9 0.023 14.7 18.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 KXZ55425.1 - 1.1 9.4 5.6 0.43 10.8 1.8 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Nop53 PF07767.11 KXZ55425.1 - 1.7 7.9 16.5 0.42 10.0 9.0 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Orf78 PF06024.12 KXZ55425.1 - 1.7 9.0 3.7 3.5 8.0 3.7 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Spt20 PF12090.8 KXZ55425.1 - 1.9 8.0 22.5 3.4 7.2 22.5 1.3 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 KXZ55425.1 - 4.8 8.2 12.9 14 6.7 9.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 KXZ55425.1 - 6.6 6.6 9.7 11 5.8 9.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FYDLN_acid PF09538.10 KXZ55425.1 - 6.7 7.4 8.9 11 6.7 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TEX19 PF15553.6 KXZ55427.1 - 5 7.1 6.0 2.6 8.0 0.0 3.1 3 0 0 3 3 3 0 Testis-expressed protein 19 Ribosomal_60s PF00428.19 KXZ55428.1 - 2.1 9.0 8.3 1 10.0 1.6 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein PTA_PTB PF01515.19 KXZ55429.1 - 3.7e-115 384.6 2.6 5e-115 384.2 2.6 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase DRTGG PF07085.12 KXZ55429.1 - 3.5e-17 62.1 0.4 4.6e-07 29.6 0.0 2.9 2 0 0 2 2 2 2 DRTGG domain AAA_26 PF13500.6 KXZ55429.1 - 7.7e-15 55.2 0.0 1.4e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF4303 PF14136.6 KXZ55429.1 - 0.0037 17.0 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4303) PFL-like PF02901.15 KXZ55429.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Pyruvate formate lyase-like NUDIX PF00293.28 KXZ55430.1 - 1.9e-14 53.8 0.0 2.4e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXZ55430.1 - 0.00057 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DoxX_2 PF13564.6 KXZ55431.1 - 0.00015 21.8 0.6 0.00015 21.8 0.6 1.8 2 0 0 2 2 2 1 DoxX-like family DoxX_2 PF13564.6 KXZ55432.1 - 4.1e-06 26.9 1.5 4.1e-06 26.9 1.5 1.9 2 0 0 2 2 2 1 DoxX-like family DUF4179 PF13786.6 KXZ55432.1 - 0.32 11.5 1.1 0.6 10.6 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) PAN_4 PF14295.6 KXZ55434.1 - 1.4e-05 24.9 8.6 0.018 15.0 0.2 2.4 2 0 0 2 2 2 2 PAN domain Pro_isomerase PF00160.21 KXZ55434.1 - 0.0039 17.5 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FeoB_associated PF12669.7 KXZ55434.1 - 0.091 13.2 2.4 0.65 10.4 0.1 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Tyr-DNA_phospho PF06087.12 KXZ55436.1 - 1.1e-82 278.2 0.0 6e-82 275.8 0.0 1.8 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Robl_LC7 PF03259.17 KXZ55436.1 - 0.18 11.6 0.0 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain LRR_6 PF13516.6 KXZ55437.1 - 5.5e-21 72.8 20.1 0.003 17.5 0.4 9.7 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 KXZ55437.1 - 2.3e-07 31.0 0.6 0.35 11.3 0.0 5.5 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ55437.1 - 8.2e-05 22.6 3.4 7.8 7.5 0.0 6.6 7 0 0 7 7 7 1 Leucine Rich Repeat NPF PF16601.5 KXZ55437.1 - 0.013 16.0 2.5 0.027 15.0 2.4 1.5 1 1 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif LRR_8 PF13855.6 KXZ55437.1 - 0.021 14.6 12.3 2 8.2 0.1 6.6 7 2 0 7 7 7 0 Leucine rich repeat AAA_16 PF13191.6 KXZ55438.1 - 3.6e-07 30.7 0.0 5.2e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Guanylate_cyc PF00211.20 KXZ55438.1 - 1.5e-06 28.0 0.1 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain AAA_22 PF13401.6 KXZ55438.1 - 0.02 15.2 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 KXZ55438.1 - 0.081 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Acetate_kinase PF00871.17 KXZ55440.1 - 5.6e-142 473.1 0.0 6.3e-142 472.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Prenyltrans PF00432.21 KXZ55441.1 - 8.1e-56 185.4 30.4 6.1e-13 48.3 2.1 6.8 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KXZ55441.1 - 0.011 14.9 0.0 20 4.2 0.0 3.9 2 2 3 5 5 5 0 Squalene-hopene cyclase N-terminal domain Ribosomal_L27 PF01016.19 KXZ55442.1 - 1.1e-20 73.5 0.2 1.3e-20 73.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein cNMP_binding PF00027.29 KXZ55443.1 - 6.3e-14 51.8 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CobW_C PF07683.14 KXZ55445.1 - 4.2e-10 39.4 0.1 4.3e-08 33.0 0.1 2.0 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain cNMP_binding PF00027.29 KXZ55446.1 - 1e-13 51.2 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KXZ55446.1 - 3.8e-11 42.7 9.4 4.8e-11 42.4 9.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KXZ55447.1 - 2.2e-05 23.8 6.3 3.4e-05 23.2 6.3 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KXZ55447.1 - 0.00013 22.0 0.1 0.00025 21.1 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PIG-Y PF15159.6 KXZ55447.1 - 0.027 15.4 4.7 5.2 8.1 0.8 2.8 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y GAS PF13851.6 KXZ55448.1 - 0.011 15.1 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IL17 PF06083.11 KXZ55448.1 - 0.087 13.3 1.9 0.16 12.5 0.6 2.0 2 0 0 2 2 2 0 Interleukin-17 Pea-VEAacid PF08111.11 KXZ55448.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Pea-VEAacid family PMC2NT PF08066.12 KXZ55448.1 - 0.16 12.7 0.1 0.38 11.5 0.0 1.7 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DHR10 PF18595.1 KXZ55448.1 - 0.39 10.8 3.4 2.8 8.0 0.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain WD40 PF00400.32 KXZ55450.1 - 2.3e-15 56.7 4.5 0.00041 21.1 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55450.1 - 1.1e-06 28.9 0.0 0.67 10.3 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXZ55450.1 - 0.037 14.5 0.1 4.5 7.9 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain zinc_ribbon_16 PF17034.5 KXZ55450.1 - 0.055 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family SBP PF03110.14 KXZ55451.1 - 6e-30 103.4 12.1 1.5e-29 102.1 12.1 1.7 1 0 0 1 1 1 1 SBP domain Ank_4 PF13637.6 KXZ55451.1 - 5.1e-06 26.9 0.1 0.1 13.2 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ55451.1 - 1.7e-05 25.3 0.0 0.00018 22.0 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ55451.1 - 5.7e-05 23.4 2.4 0.06 13.8 0.1 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KXZ55451.1 - 0.00018 21.7 0.6 3.1 8.7 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeat TIG PF01833.24 KXZ55451.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 IPT/TIG domain TPT PF03151.16 KXZ55452.1 - 4.9e-116 387.1 10.5 5.6e-116 386.9 10.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ55452.1 - 1.6e-13 51.0 21.6 1.3e-06 28.7 10.3 2.5 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.11 KXZ55452.1 - 0.00054 19.3 10.4 0.0015 17.8 10.4 1.6 1 1 0 1 1 1 1 UAA transporter family DUF676 PF05057.14 KXZ55452.1 - 0.018 14.6 1.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) TraL PF07178.11 KXZ55452.1 - 0.5 10.9 2.8 41 4.7 0.1 3.5 2 1 2 4 4 4 0 TraL protein TMEM135_C_rich PF15982.5 KXZ55453.1 - 2.8e-07 31.2 0.3 6.5e-07 30.0 0.3 1.5 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 DcuC PF03606.15 KXZ55453.1 - 0.32 9.4 5.9 0.55 8.6 5.9 1.3 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Peptidase_M50 PF02163.22 KXZ55454.1 - 0.015 14.5 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M50 KH_1 PF00013.29 KXZ55455.1 - 9.4e-12 44.6 0.3 7.3e-10 38.5 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KXZ55455.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 KH domain Glyco_hydro_2_C PF02836.17 KXZ55456.1 - 9.8e-82 274.4 0.0 1.2e-81 274.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXZ55456.1 - 1.7e-49 168.7 0.0 9.4e-49 166.2 0.0 2.1 1 1 0 1 1 1 1 Beta galactosidase small chain DUF4981 PF16353.5 KXZ55456.1 - 2.9e-10 40.5 0.7 3.1e-08 34.0 0.2 3.3 2 1 0 2 2 2 1 Domain of unknown function(DUF4981) NTS_2 PF15448.6 KXZ55456.1 - 0.047 14.1 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein Pkinase_Tyr PF07714.17 KXZ55457.1 - 4.2e-42 144.2 0.0 3.8e-33 114.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ55457.1 - 2.3e-41 141.9 0.0 1.7e-30 106.3 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Kdo PF06293.14 KXZ55457.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ55457.1 - 0.1 12.5 0.2 0.27 11.1 0.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family EF_assoc_1 PF08355.12 KXZ55457.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 EF hand associated MFS_1 PF07690.16 KXZ55458.1 - 1.7e-41 142.4 40.7 1.7e-41 142.4 40.7 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 KXZ55461.1 - 4.4e-21 75.2 0.0 3.8e-20 72.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ55461.1 - 1.1e-14 54.6 0.0 1.1e-13 51.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.6 KXZ55461.1 - 0.03 15.0 0.0 0.072 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KXZ55462.1 - 2.7e-52 177.8 0.0 3.5e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55462.1 - 1.5e-19 70.3 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ55462.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ55462.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FGE-sulfatase PF03781.16 KXZ55463.1 - 6.8e-23 81.6 4.1 6.8e-23 81.6 1.1 2.4 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 Methyltransf_31 PF13847.6 KXZ55463.1 - 2.6e-17 63.0 0.0 1.8e-07 31.1 0.1 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ55463.1 - 1.6e-16 60.7 0.0 1.6e-15 57.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ55463.1 - 5.2e-16 59.1 0.0 7.2e-14 52.3 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ55463.1 - 2.6e-13 50.1 0.0 4.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ55463.1 - 1.4e-12 48.2 0.0 7.3e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 KXZ55463.1 - 0.018 15.6 0.3 0.018 15.6 0.3 2.1 2 0 0 2 2 2 0 DinB superfamily Ubie_methyltran PF01209.18 KXZ55463.1 - 0.02 14.2 0.0 1.4 8.2 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CP12 PF02672.15 KXZ55464.1 - 3.6e-23 82.1 4.4 4.6e-23 81.7 4.4 1.1 1 0 0 1 1 1 1 CP12 domain QRPTase_C PF01729.19 KXZ55464.1 - 0.066 13.0 0.4 0.079 12.7 0.4 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain CorA PF01544.18 KXZ55465.1 - 8.5e-36 123.8 1.9 1.6e-23 83.5 0.1 3.0 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Gag_p17 PF00540.18 KXZ55465.1 - 0.21 11.6 0.2 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) 2OG-FeII_Oxy_3 PF13640.6 KXZ55466.1 - 3.9e-13 50.1 0.0 5.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ55466.1 - 0.004 17.6 0.0 0.0068 16.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CitF PF04223.12 KXZ55466.1 - 0.094 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Pkinase PF00069.25 KXZ55467.1 - 2.9e-13 49.8 0.0 1.2e-11 44.5 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55467.1 - 3.8e-12 46.0 0.0 3.4e-10 39.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ55467.1 - 0.0026 16.6 0.0 0.0034 16.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ55469.1 - 7.2e-16 58.2 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ55469.1 - 6.9e-14 51.8 0.0 9.2e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KXZ55470.1 - 5.4e-25 88.3 0.0 4.6e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55470.1 - 1.2e-24 87.0 0.0 1.3e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ55470.1 - 0.051 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DHquinase_I PF01487.15 KXZ55471.1 - 8.6e-58 196.3 0.0 1.4e-57 195.6 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KXZ55471.1 - 5.3e-27 93.9 0.0 3.1e-26 91.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXZ55471.1 - 7.1e-12 44.9 2.4 1.7e-11 43.7 2.4 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXZ55471.1 - 7.2e-09 35.8 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXZ55471.1 - 7.4e-07 29.7 1.8 1.2e-06 29.0 0.8 1.9 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 KXZ55471.1 - 2.4e-05 23.6 2.4 4.8e-05 22.6 2.4 1.6 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 KXZ55471.1 - 0.00017 21.8 0.6 0.016 15.5 0.6 2.9 2 2 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KXZ55471.1 - 0.00022 20.7 1.9 0.0003 20.3 0.7 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KXZ55471.1 - 0.00027 20.4 0.2 0.00053 19.4 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KXZ55471.1 - 0.0015 17.8 1.1 0.0027 17.0 1.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KXZ55471.1 - 0.0075 15.9 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KXZ55471.1 - 0.018 14.9 1.1 0.031 14.1 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXZ55471.1 - 0.036 14.2 0.2 0.036 14.2 0.2 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 KXZ55471.1 - 0.037 13.1 2.7 0.059 12.4 2.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AdoHcyase_NAD PF00670.21 KXZ55471.1 - 0.049 13.7 0.8 0.14 12.2 0.8 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KXZ55471.1 - 0.081 12.2 4.7 0.14 11.4 4.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KXZ55471.1 - 0.11 13.3 0.3 0.28 12.0 0.1 1.8 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.23 KXZ55471.1 - 0.14 12.1 0.6 0.29 11.1 0.6 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 KXZ55471.1 - 0.21 10.8 0.2 0.33 10.2 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXZ55471.1 - 0.32 9.7 4.2 0.45 9.1 4.2 1.2 1 0 0 1 1 1 0 HI0933-like protein WSD PF15613.6 KXZ55472.1 - 3.7e-12 46.6 0.1 3.7e-12 46.6 0.1 3.2 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 KXZ55472.1 - 2.7e-09 36.8 6.7 5.2e-09 35.9 6.7 1.5 1 0 0 1 1 1 1 PHD-finger MBD PF01429.19 KXZ55472.1 - 1.3e-06 28.0 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain FYRC PF05965.14 KXZ55472.1 - 3.4e-05 23.9 0.0 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 KXZ55472.1 - 0.0024 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus WHIM1 PF15612.6 KXZ55472.1 - 0.0032 17.0 0.0 0.0073 15.8 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 zf-RING_2 PF13639.6 KXZ55472.1 - 9.3 6.7 8.0 17 5.9 8.0 1.4 1 0 0 1 1 1 0 Ring finger domain HORMA PF02301.18 KXZ55473.1 - 1.7e-23 83.3 0.1 3.7e-23 82.2 0.1 1.5 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KXZ55473.1 - 0.00024 21.0 0.2 0.0005 20.0 0.2 1.6 1 1 0 1 1 1 1 Bacterial HORMA domain 2 PMSR PF01625.21 KXZ55474.1 - 1.2e-56 191.1 0.7 1.4e-56 190.9 0.0 1.4 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase Rubis-subs-bind PF09273.11 KXZ55475.1 - 1.8e-13 51.3 0.0 2.6e-12 47.6 0.0 2.8 3 1 0 3 3 3 1 Rubisco LSMT substrate-binding SET PF00856.28 KXZ55475.1 - 7.7e-07 29.6 0.0 2.3e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 SET domain TMCO5 PF14992.6 KXZ55476.1 - 0.0075 15.9 1.4 0.0094 15.6 1.4 1.2 1 0 0 1 1 1 1 TMCO5 family FlaC_arch PF05377.11 KXZ55476.1 - 0.012 15.9 1.8 0.54 10.7 0.2 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 KXZ55476.1 - 0.013 15.5 14.9 0.29 11.2 2.4 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KXZ55476.1 - 0.017 14.0 12.0 0.033 13.1 12.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 KXZ55476.1 - 0.069 13.3 6.7 0.19 11.9 2.9 2.7 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 Rab5-bind PF09311.11 KXZ55476.1 - 0.096 12.1 10.9 1.7 8.0 0.4 2.2 1 1 1 2 2 2 0 Rabaptin-like protein DUF2844 PF11005.8 KXZ55476.1 - 0.096 12.7 0.0 0.096 12.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2844) Exonuc_VII_L PF02601.15 KXZ55476.1 - 0.097 12.2 4.1 0.13 11.8 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 KXZ55476.1 - 0.1 11.9 11.2 0.21 10.9 11.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 KXZ55476.1 - 0.14 11.6 6.8 0.018 14.5 3.0 1.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3818 PF12825.7 KXZ55476.1 - 0.16 11.0 0.1 0.29 10.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) WD40_alt PF14077.6 KXZ55476.1 - 0.23 11.4 1.3 1.1 9.2 1.3 1.9 1 1 1 2 2 2 0 Alternative WD40 repeat motif DUF5082 PF16888.5 KXZ55476.1 - 0.47 10.8 4.8 4.6 7.5 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) AIP3 PF03915.13 KXZ55476.1 - 0.68 9.0 6.3 0.055 12.6 1.7 1.4 2 0 0 2 2 2 0 Actin interacting protein 3 Jnk-SapK_ap_N PF09744.9 KXZ55476.1 - 0.89 9.8 11.3 2.6 8.3 11.1 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 LUC7 PF03194.15 KXZ55476.1 - 0.96 9.1 6.5 1.5 8.4 6.5 1.4 1 1 0 1 1 1 0 LUC7 N_terminus SHE3 PF17078.5 KXZ55476.1 - 1 9.0 5.7 2.1 8.0 5.7 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Fungal_TACC PF12709.7 KXZ55476.1 - 1.8 9.1 7.4 8.6 6.9 1.5 2.6 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins CENP-H PF05837.12 KXZ55476.1 - 1.9 8.9 15.9 0.053 13.9 6.3 2.5 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Syntaxin-6_N PF09177.11 KXZ55476.1 - 2.7 8.6 7.4 1.8 9.2 2.7 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Rho_Binding PF08912.11 KXZ55476.1 - 2.8 8.8 14.7 13 6.7 0.3 3.4 1 1 2 3 3 3 0 Rho Binding TPPII_N PF12583.8 KXZ55476.1 - 3.3 8.3 13.9 8.5 7.0 13.9 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal KASH_CCD PF14662.6 KXZ55476.1 - 3.4 7.5 16.9 1.1 9.0 0.5 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Helo_like_N PF17111.5 KXZ55476.1 - 3.6 6.9 7.3 1.5 8.1 2.6 2.1 1 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF4795 PF16043.5 KXZ55476.1 - 4.2 6.9 8.8 6.9 6.2 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TPR_MLP1_2 PF07926.12 KXZ55476.1 - 5 7.2 29.6 2.7 8.1 12.0 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Nnf1 PF03980.14 KXZ55476.1 - 5.4 7.5 15.9 8.6 6.8 8.8 3.2 2 1 1 3 3 3 0 Nnf1 DUF4407 PF14362.6 KXZ55476.1 - 7.6 5.8 25.5 1.8e+02 1.3 25.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fer4_13 PF13370.6 KXZ55477.1 - 3.6e-14 53.0 1.5 8.3e-14 51.9 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Lactamase_B PF00753.27 KXZ55477.1 - 1.8e-07 31.3 2.1 4.9e-05 23.4 0.0 2.8 3 1 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 KXZ55477.1 - 0.041 13.4 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily NUDIX PF00293.28 KXZ55479.1 - 3.9e-17 62.5 0.1 5.2e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain FAST_1 PF06743.15 KXZ55480.1 - 3.1e-06 27.0 0.0 1.8 8.6 0.0 5.3 5 1 1 6 6 6 4 FAST kinase-like protein, subdomain 1 Arm PF00514.23 KXZ55481.1 - 4e-08 33.0 7.4 0.014 15.5 0.0 5.1 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXZ55481.1 - 0.0043 17.4 0.5 0.013 15.9 0.5 1.9 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KXZ55481.1 - 0.0048 17.0 1.0 0.022 15.0 0.2 2.5 2 0 0 2 2 2 1 HEAT repeat PaaA_PaaC PF05138.12 KXZ55481.1 - 0.011 15.0 0.0 0.022 13.9 0.0 1.4 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein HEAT_EZ PF13513.6 KXZ55481.1 - 0.031 14.8 0.3 0.031 14.8 0.3 3.0 3 0 0 3 3 3 0 HEAT-like repeat Se-cys_synth_N PF12390.8 KXZ55481.1 - 0.17 12.2 2.6 6.7 7.0 0.1 3.7 3 0 0 3 3 3 0 Selenocysteine synthase N terminal Glyco_hydro_1 PF00232.18 KXZ55482.1 - 3.8e-16 58.6 0.2 4.6e-16 58.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 KXZ55482.1 - 0.0065 15.7 0.0 0.0074 15.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 WHEP-TRS PF00458.20 KXZ55483.1 - 8.1e-08 32.3 3.7 1.5e-07 31.4 3.7 1.4 1 0 0 1 1 1 1 WHEP-TRS domain Ribosomal_60s PF00428.19 KXZ55484.1 - 0.00077 20.0 11.4 0.00077 20.0 11.4 2.9 3 0 0 3 3 3 1 60s Acidic ribosomal protein G-patch PF01585.23 KXZ55485.1 - 2.9e-14 52.7 1.2 5.2e-14 51.9 0.3 2.0 2 0 0 2 2 2 1 G-patch domain Surp PF01805.20 KXZ55485.1 - 1.4e-10 40.9 0.4 4.5e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Surp module G-patch_2 PF12656.7 KXZ55485.1 - 6.8e-05 22.9 0.3 0.00023 21.2 0.3 1.9 1 0 0 1 1 1 1 G-patch domain Ank_2 PF12796.7 KXZ55486.1 - 9e-05 23.0 2.8 1.2 9.8 0.4 4.2 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ55486.1 - 0.12 13.0 5.2 43 4.8 0.0 5.8 6 2 1 7 7 7 0 Ankyrin repeats (many copies) AbiEi_3_N PF17194.4 KXZ55486.1 - 0.15 12.1 0.2 44 4.2 0.0 3.6 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Defensin_4 PF07936.12 KXZ55486.1 - 2.6 8.0 8.8 27 4.7 0.4 4.1 4 0 0 4 4 4 0 Potassium-channel blocking toxin adh_short PF00106.25 KXZ55487.1 - 1e-28 100.1 0.0 3.5e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ55487.1 - 3.8e-20 72.5 0.0 8.8e-17 61.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ55487.1 - 5e-11 42.8 0.1 7.7e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXZ55487.1 - 0.003 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4823 PF16105.5 KXZ55487.1 - 0.022 14.7 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) Pyr_redox_3 PF13738.6 KXZ55487.1 - 0.2 10.9 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPR_2 PF07719.17 KXZ55488.1 - 4.8e-10 38.8 4.8 0.0061 16.6 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ55488.1 - 1.6e-08 34.0 7.3 0.011 15.5 0.9 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ55488.1 - 5.6e-05 22.7 7.4 6.6e-05 22.5 1.7 2.6 2 1 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 KXZ55488.1 - 9.2e-05 22.6 0.1 0.00044 20.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ55488.1 - 0.00029 20.8 8.0 2 8.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ55488.1 - 0.0014 19.1 0.5 0.0014 19.1 0.5 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ55488.1 - 0.003 18.2 0.1 0.003 18.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ55488.1 - 0.0079 16.5 1.6 1.7 9.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ55488.1 - 0.55 11.2 5.8 16 6.7 0.1 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat NAD_binding_8 PF13450.6 KXZ55489.1 - 7e-11 42.2 0.1 6.5e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ55489.1 - 0.00012 21.7 0.1 0.00024 20.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ55489.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXZ55489.1 - 0.032 14.2 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KXZ55489.1 - 0.034 13.4 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KXZ55489.1 - 0.049 12.7 0.2 0.049 12.7 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KXZ55489.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein GARS_N PF02844.15 KXZ55489.1 - 0.1 13.4 0.0 0.26 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain GIDA PF01134.22 KXZ55489.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A mTERF PF02536.14 KXZ55490.1 - 3.9e-09 35.9 0.0 6.9e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 mTERF N_formyltrans_C PF18216.1 KXZ55490.1 - 0.097 12.4 0.0 9 6.1 0.0 2.4 2 0 0 2 2 2 0 N-formyltransferase dimerization C-terminal domain Exostosin PF03016.15 KXZ55491.1 - 3.3e-31 108.6 0.0 4.5e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ55491.1 - 9.1e-07 29.1 34.0 0.0003 21.1 9.3 3.6 3 0 0 3 3 3 2 EGF-like domain ThiS PF02597.20 KXZ55492.1 - 1.5e-19 70.4 0.0 1.7e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 ThiS family AP2 PF00847.20 KXZ55493.1 - 0.0001 22.4 0.0 0.0001 22.4 0.0 2.6 3 0 0 3 3 3 1 AP2 domain Actin PF00022.19 KXZ55494.1 - 7.2e-82 275.2 0.0 4.7e-81 272.5 0.0 1.8 1 1 0 1 1 1 1 Actin Acid_phosphat_B PF03767.14 KXZ55495.1 - 1.5e-19 70.5 0.0 3.1e-06 27.0 0.0 3.2 3 0 0 3 3 3 3 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF2608 PF11019.8 KXZ55495.1 - 0.089 12.3 0.0 14 5.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) DUF3807 PF12720.7 KXZ55495.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Hydrolase_6 PF13344.6 KXZ55495.1 - 0.2 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CCB2_CCB4 PF11152.8 KXZ55496.1 - 1.4e-58 197.5 0.0 1.4e-58 197.5 0.0 1.9 2 0 0 2 2 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 Med15 PF09606.10 KXZ55496.1 - 0.002 16.9 27.5 0.002 16.9 27.5 1.4 2 0 0 2 2 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AIF_C PF14721.6 KXZ55496.1 - 0.0075 16.6 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2561 PF10812.8 KXZ55496.1 - 0.011 15.7 4.6 0.011 15.7 4.6 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2561) CCDC53 PF10152.9 KXZ55496.1 - 0.012 16.0 3.9 0.021 15.2 3.9 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RIC3 PF15361.6 KXZ55496.1 - 0.027 14.9 1.2 0.054 13.9 1.2 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Pex14_N PF04695.13 KXZ55496.1 - 0.036 14.7 11.5 0.073 13.7 11.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 KXZ55496.1 - 0.04 13.9 16.0 0.058 13.4 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 KXZ55496.1 - 0.041 11.0 0.5 0.047 10.8 0.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DDHD PF02862.17 KXZ55496.1 - 0.084 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 KXZ55496.1 - 0.44 10.3 3.6 0.71 9.6 3.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Alpha_GJ PF03229.13 KXZ55496.1 - 0.77 10.3 25.3 1.1 9.8 7.1 2.5 2 0 0 2 2 2 0 Alphavirus glycoprotein J RNA_pol_Rpc4 PF05132.14 KXZ55496.1 - 1.7 9.1 6.8 0.38 11.2 3.1 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 MTBP_C PF14920.6 KXZ55496.1 - 4.2 7.1 7.9 9.3 5.9 7.9 1.5 1 0 0 1 1 1 0 MDM2-binding Rrn6 PF10214.9 KXZ55496.1 - 6.8 5.0 9.1 9.3 4.6 9.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 KXZ55496.1 - 7.1 5.3 10.0 11 4.7 10.0 1.2 1 0 0 1 1 1 0 Presenilin Cdh1_DBD_1 PF18196.1 KXZ55496.1 - 9.6 6.5 6.5 18 5.7 6.5 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 TPT PF03151.16 KXZ55498.1 - 6.1e-19 68.5 23.9 7.3e-19 68.2 23.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXZ55498.1 - 2.6e-07 30.2 25.5 3.9e-07 29.6 25.5 1.2 1 0 0 1 1 1 1 UAA transporter family DUF4094 PF13334.6 KXZ55498.1 - 0.026 14.9 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Pkinase PF00069.25 KXZ55500.1 - 7.5e-47 159.9 0.0 1.3e-46 159.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55500.1 - 9.8e-18 64.4 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ55500.1 - 2e-05 24.6 0.1 2e-05 24.6 0.1 4.1 4 0 0 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXZ55500.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S25 PF03297.15 KXZ55502.1 - 4e-41 139.3 4.6 4.5e-41 139.1 4.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KXZ55502.1 - 0.0017 17.9 0.1 0.0022 17.5 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding FtsK_gamma PF09397.10 KXZ55502.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Ftsk gamma domain MarR_2 PF12802.7 KXZ55502.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 MarR family PCI PF01399.27 KXZ55502.1 - 0.017 15.6 0.0 0.017 15.6 0.0 1.1 1 0 0 1 1 1 0 PCI domain RNA_pol_Rpc34 PF05158.12 KXZ55502.1 - 0.037 13.4 0.0 0.051 12.9 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KXZ55502.1 - 0.15 12.8 0.0 0.19 12.4 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal DUF2169 PF09937.9 KXZ55504.1 - 0.092 12.2 2.4 0.11 11.9 2.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) PGAP1 PF07819.13 KXZ55505.1 - 0.0041 16.9 0.0 0.0067 16.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KXZ55505.1 - 0.13 11.7 1.0 0.2 11.1 0.1 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) BACK PF07707.15 KXZ55506.1 - 3.5e-05 23.9 0.0 7.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF829 PF05705.14 KXZ55507.1 - 9e-27 94.5 0.3 7.6e-20 71.8 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 KXZ55507.1 - 0.0087 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_transf_20 PF00982.21 KXZ55508.1 - 1.7e-141 472.2 0.0 2.1e-141 471.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 MazG-like PF12643.7 KXZ55509.1 - 8.2e-09 35.6 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 KXZ55509.1 - 8.8e-08 32.2 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain STIMATE PF12400.8 KXZ55510.1 - 4.3e-22 79.0 0.0 5.3e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 STIMATE family NRBF2 PF08961.10 KXZ55511.1 - 0.48 10.0 1.1 1 8.9 1.1 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator E3_UFM1_ligase PF09743.9 KXZ55512.1 - 3.7e-86 289.1 0.0 4.7e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 HTH_9 PF08221.11 KXZ55512.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DPBB_1 PF03330.18 KXZ55513.1 - 1.8e-14 53.8 0.3 3.2e-14 52.9 0.3 1.4 1 0 0 1 1 1 1 Lytic transglycolase DPBB_1 PF03330.18 KXZ55514.1 - 4.7e-14 52.4 0.1 7e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Lytic transglycolase WD40 PF00400.32 KXZ55516.1 - 1.6e-14 54.0 5.3 3.6e-05 24.4 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55516.1 - 1.1e-05 25.6 0.1 2.2e-05 24.7 0.1 1.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ55516.1 - 0.14 12.0 0.0 0.46 10.3 0.0 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Mob1_phocein PF03637.17 KXZ55520.1 - 7.1e-75 250.7 0.1 8.7e-75 250.4 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Imm47 PF15573.6 KXZ55520.1 - 0.059 12.9 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 47 Aldedh PF00171.22 KXZ55521.1 - 1.5e-167 557.8 0.1 1.8e-167 557.6 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXZ55521.1 - 0.085 12.3 0.0 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF3611 PF12263.8 KXZ55522.1 - 9.8e-31 107.0 16.6 1.2e-30 106.8 16.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Methyltransf_25 PF13649.6 KXZ55523.1 - 3.7e-12 46.8 1.7 1.3e-11 45.0 0.1 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ55523.1 - 1.4e-09 38.5 0.1 7.2e-09 36.2 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXZ55523.1 - 1.1e-07 31.6 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXZ55523.1 - 7.3e-07 29.1 0.0 2.7e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ55523.1 - 2.9e-06 27.2 0.0 6.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ55523.1 - 4.9e-06 27.2 0.4 3.3e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 KXZ55523.1 - 0.002 17.7 1.6 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 KXZ55523.1 - 0.0031 16.9 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KXZ55523.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KXZ55523.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KXZ55523.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 KXZ55523.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KXZ55523.1 - 0.04 12.8 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) bZIP_2 PF07716.15 KXZ55523.1 - 0.13 12.4 0.9 2.6 8.2 0.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper CAS_CSE1 PF03378.15 KXZ55524.1 - 9.1e-120 400.1 0.0 2e-119 399.0 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KXZ55524.1 - 5.3e-106 354.5 0.0 8.5e-106 353.9 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KXZ55524.1 - 7.3e-14 51.4 0.1 1.2e-12 47.5 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KXZ55524.1 - 0.0068 16.4 0.7 8.6 6.6 0.2 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.12 KXZ55524.1 - 0.064 13.3 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Exportin 1-like protein DUF1839 PF08893.10 KXZ55524.1 - 0.081 12.1 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1839) DUF368 PF04018.13 KXZ55524.1 - 0.096 12.3 0.5 29 4.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF368) SUR7 PF06687.12 KXZ55526.1 - 0.0071 16.0 1.5 0.36 10.4 0.0 2.2 2 0 0 2 2 2 1 SUR7/PalI family YukD PF08817.10 KXZ55526.1 - 0.03 15.0 0.2 0.065 13.9 0.2 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Mito_fiss_reg PF05308.11 KXZ55526.1 - 0.77 9.8 2.9 2 8.4 1.3 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator SMN PF06003.12 KXZ55526.1 - 1.6 8.0 5.6 2.7 7.2 5.6 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ribosomal_L11_N PF03946.14 KXZ55526.1 - 1.7 8.5 3.5 14 5.6 0.5 2.7 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain CRAL_TRIO PF00650.20 KXZ55527.1 - 6.1e-21 74.8 0.0 1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain RRM_1 PF00076.22 KXZ55528.1 - 6e-56 186.2 0.0 2.2e-17 62.6 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.6 KXZ55528.1 - 9.2e-35 118.8 36.4 6.9e-09 35.9 2.1 8.1 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ55528.1 - 1.3e-13 50.3 42.4 2.5e-05 24.0 0.2 10.2 12 0 0 12 12 12 6 Tetratricopeptide repeat RRM_occluded PF16842.5 KXZ55528.1 - 4.9e-05 23.1 0.0 0.92 9.4 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif TPR_2 PF07719.17 KXZ55528.1 - 0.00027 20.8 14.7 3 8.2 0.1 7.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ55528.1 - 0.0064 16.3 3.9 3.9 7.5 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ55528.1 - 0.044 13.8 7.8 17 5.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ55528.1 - 0.045 14.4 0.7 0.045 14.4 0.7 11.9 12 0 0 12 12 12 0 Tetratricopeptide repeat RRM_1 PF00076.22 KXZ55529.1 - 7.9e-14 51.2 0.0 1.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KXZ55529.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 BRCA1-associated protein 2 DUF5320 PF17253.2 KXZ55530.1 - 0.12 13.5 13.8 0.16 13.1 13.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Keratin_2_head PF16208.5 KXZ55530.1 - 2.7 8.1 32.9 3.5 7.7 32.9 1.2 1 0 0 1 1 1 0 Keratin type II head Tetraspanin PF00335.20 KXZ55533.1 - 0.042 13.6 6.1 0.05 13.3 6.1 1.2 1 0 0 1 1 1 0 Tetraspanin family MARVEL PF01284.23 KXZ55533.1 - 0.69 9.9 12.1 1.1 9.3 12.1 1.4 1 1 0 1 1 1 0 Membrane-associating domain OppC_N PF12911.7 KXZ55533.1 - 6.3 6.9 11.5 2.2 8.3 0.2 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Methyltransf_4 PF02390.17 KXZ55534.1 - 3.6e-10 39.6 0.0 4.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase TT_ORF2 PF02957.15 KXZ55534.1 - 0.026 15.5 2.3 0.042 14.8 2.3 1.3 1 0 0 1 1 1 0 TT viral ORF2 LRR_8 PF13855.6 KXZ55535.1 - 7.3e-16 57.7 7.4 2.3e-09 36.9 1.8 2.4 2 0 0 2 2 2 2 Leucine rich repeat ubiquitin PF00240.23 KXZ55535.1 - 1e-10 41.2 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family LRR_4 PF12799.7 KXZ55535.1 - 1.2e-06 28.7 6.3 0.013 15.9 0.2 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXZ55535.1 - 0.005 16.4 0.1 0.25 10.8 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat Ubiquitin_5 PF18037.1 KXZ55535.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD PF11976.8 KXZ55535.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KXZ55535.1 - 0.16 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain EBP50_C PF09007.11 KXZ55535.1 - 0.17 12.9 3.5 0.37 11.8 3.5 1.5 1 0 0 1 1 1 0 EBP50, C-terminal LRR_6 PF13516.6 KXZ55535.1 - 3.9 7.8 5.2 3.2 8.0 0.2 3.4 3 1 1 4 4 4 0 Leucine Rich repeat Aldo_ket_red PF00248.21 KXZ55536.1 - 7.5e-58 196.0 0.0 9.1e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NCBP3 PF10309.9 KXZ55537.1 - 3.2e-18 65.3 0.0 4.9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KXZ55537.1 - 0.0012 18.9 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain Tho1_MOS11_C PF18592.1 KXZ55537.1 - 0.026 14.3 3.7 1.6 8.6 0.3 2.9 2 1 0 2 2 2 0 Tho1/MOS11 C-terminal domain cobW PF02492.19 KXZ55538.1 - 1.6e-55 187.5 0.3 2.1e-55 187.0 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXZ55538.1 - 3.9e-21 74.8 0.0 7.9e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain WW PF00397.26 KXZ55538.1 - 7.3e-09 35.6 1.4 1.4e-08 34.6 1.4 1.5 1 0 0 1 1 1 1 WW domain RsgA_GTPase PF03193.16 KXZ55538.1 - 2.6e-05 24.2 0.3 0.15 12.0 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXZ55538.1 - 0.022 14.3 0.0 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXZ55538.1 - 0.026 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ55538.1 - 0.027 14.8 0.1 0.088 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 KXZ55538.1 - 0.035 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KXZ55538.1 - 0.037 13.5 0.4 5.4 6.4 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KXZ55538.1 - 0.052 14.1 0.2 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RTT107_BRCT_6 PF16771.5 KXZ55538.1 - 0.07 13.3 0.4 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain T2SSE PF00437.20 KXZ55538.1 - 0.076 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KXZ55538.1 - 0.084 13.0 0.4 0.53 10.4 0.4 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXZ55538.1 - 0.087 13.3 0.1 0.16 12.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KXZ55538.1 - 0.12 11.7 0.2 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KXZ55538.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 KXZ55538.1 - 0.6 9.9 2.3 1.5 8.7 0.0 2.4 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_23 PF13476.6 KXZ55538.1 - 0.63 10.5 3.9 0.23 11.9 0.7 1.8 2 0 0 2 2 2 0 AAA domain DUF4521 PF15021.6 KXZ55539.1 - 0.013 15.4 0.8 0.02 14.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Atg14 PF10186.9 KXZ55539.1 - 9.2 5.2 8.4 18 4.3 8.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YGGT PF02325.17 KXZ55540.1 - 2.4e-17 63.1 2.8 3.9e-17 62.4 2.8 1.3 1 0 0 1 1 1 1 YGGT family NAD_binding_2 PF03446.15 KXZ55542.1 - 1.6e-28 99.9 0.2 2.3e-28 99.4 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXZ55542.1 - 5.3e-14 52.5 0.4 1.3e-13 51.3 0.4 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KXZ55542.1 - 3.4e-08 33.0 0.2 5.5e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXZ55542.1 - 4.5e-08 33.6 1.5 1.1e-07 32.3 1.2 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXZ55542.1 - 1.3e-05 25.2 0.4 2.4e-05 24.3 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXZ55542.1 - 1.4e-05 25.2 0.2 2.3e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KXZ55542.1 - 0.00034 20.2 0.3 0.00051 19.6 0.3 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KXZ55542.1 - 0.00069 19.3 0.2 0.0012 18.5 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KXZ55542.1 - 0.002 18.1 0.6 0.0064 16.5 0.8 2.0 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KXZ55542.1 - 0.0096 16.2 0.3 0.019 15.2 0.3 1.5 1 0 0 1 1 1 1 TrkA-N domain Pkinase PF00069.25 KXZ55543.1 - 6.6e-53 179.8 0.0 6e-52 176.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55543.1 - 4.3e-26 91.8 0.0 6.2e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ55543.1 - 2.1e-10 40.4 0.0 3.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ55543.1 - 1.8e-06 28.1 4.3 0.00065 19.7 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ55543.1 - 5.2e-05 22.2 0.0 0.00012 21.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXZ55543.1 - 0.085 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec5 PF15469.6 KXZ55544.1 - 2e-24 86.5 0.0 3.4e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KXZ55544.1 - 5e-07 29.7 0.1 1.3e-05 25.2 0.1 2.6 2 0 0 2 2 2 1 Vps51/Vps67 DUF5540 PF17694.1 KXZ55544.1 - 0.042 14.4 2.3 0.18 12.3 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5540) DUF4851 PF16143.5 KXZ55545.1 - 0.055 12.9 1.8 0.095 12.1 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) TSSC4 PF15264.6 KXZ55547.1 - 0.04 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Mpv17_PMP22 PF04117.12 KXZ55548.1 - 3.2e-11 43.3 1.8 1e-10 41.7 0.6 2.5 1 1 1 2 2 2 1 Mpv17 / PMP22 family TRAM_LAG1_CLN8 PF03798.16 KXZ55548.1 - 8.4e-08 32.2 25.2 8.4e-08 32.2 25.2 2.0 2 1 0 2 2 2 1 TLC domain Pkinase_Tyr PF07714.17 KXZ55549.1 - 6.4e-43 146.9 0.0 4.1e-41 141.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ55549.1 - 1.4e-38 132.8 0.0 2.2e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KXZ55551.1 - 0.13 12.6 0.2 0.37 11.2 0.2 1.8 1 0 0 1 1 1 0 HEAT repeat Amino_oxidase PF01593.24 KXZ55553.1 - 4.5e-12 46.0 0.1 9.8e-11 41.6 0.0 2.6 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ55553.1 - 0.0018 18.5 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HEM4 PF02602.15 KXZ55554.1 - 8.8e-18 64.5 0.0 1.2e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Isochorismatase PF00857.20 KXZ55555.1 - 7.3e-32 110.9 0.1 8.1e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Trypan_glycop PF00913.19 KXZ55556.1 - 0.046 13.0 3.1 0.1 11.8 3.1 1.5 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) GAS PF13851.6 KXZ55556.1 - 0.74 9.1 8.0 1.2 8.4 8.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding cNMP_binding PF00027.29 KXZ55557.1 - 1.6e-16 60.1 0.0 1.6e-14 53.7 0.0 3.1 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain ABC2_membrane_3 PF12698.7 KXZ55558.1 - 4.3e-15 55.7 5.2 5.9e-15 55.2 5.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KXZ55558.1 - 5.3e-15 56.1 0.0 9e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Mpv17_PMP22 PF04117.12 KXZ55559.1 - 6e-15 55.2 1.7 3.3e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Mpv17 / PMP22 family Ribosomal_S13 PF00416.22 KXZ55561.1 - 1.1e-07 32.3 0.4 0.00057 20.3 0.4 2.1 1 1 1 2 2 2 2 Ribosomal protein S13/S18 ADP_ribosyl_GH PF03747.14 KXZ55562.1 - 2e-27 96.7 3.5 3.1e-27 96.0 3.5 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase BRCT PF00533.26 KXZ55564.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXZ55564.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KXZ55564.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DUF1499 PF07386.11 KXZ55565.1 - 4.7e-13 49.7 0.0 5.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Ank_4 PF13637.6 KXZ55566.1 - 1.2e-15 57.7 0.1 5.4e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RRM_1 PF00076.22 KXZ55566.1 - 6.1e-15 54.8 0.8 4.1e-11 42.5 0.1 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 KXZ55566.1 - 3.2e-14 53.3 0.3 5.3e-12 46.2 0.3 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ55566.1 - 8e-11 42.0 1.8 0.00064 20.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55566.1 - 1.5e-10 40.4 0.2 0.022 15.3 0.1 4.0 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.30 KXZ55566.1 - 2.1e-08 34.2 1.4 0.12 12.9 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat STI1 PF17830.1 KXZ55566.1 - 7.6e-05 22.6 7.7 0.00035 20.4 1.2 2.6 2 0 0 2 2 2 1 STI1 domain RRM_5 PF13893.6 KXZ55566.1 - 0.00021 20.9 0.0 0.00057 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KXZ55566.1 - 0.03 14.2 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF4413 PF14372.6 KXZ55566.1 - 0.11 12.8 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) DbpA PF03880.15 KXZ55566.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 DbpA RNA binding domain CAP PF00188.26 KXZ55566.1 - 0.28 12.0 1.5 0.8 10.5 1.5 1.7 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Nup35_RRM_2 PF14605.6 KXZ55566.1 - 0.59 10.2 2.0 1.3 9.1 0.0 2.4 3 0 0 3 3 2 0 Nup53/35/40-type RNA recognition motif RRP36 PF06102.12 KXZ55566.1 - 1.2 9.1 4.1 0.37 10.7 0.9 1.8 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 GidB PF02527.15 KXZ55567.1 - 9.1e-46 155.5 0.0 2.6e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G MTS PF05175.14 KXZ55567.1 - 0.00048 19.7 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXZ55567.1 - 0.0012 19.6 0.0 0.0029 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ55567.1 - 0.0024 18.5 0.0 0.0054 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ55567.1 - 0.0028 17.4 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KXZ55567.1 - 0.07 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase MSP1_C PF07462.11 KXZ55567.1 - 6.6 5.3 4.1 1.1 7.9 0.1 1.6 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus CitMHS PF03600.16 KXZ55568.1 - 1.1e-05 24.9 2.1 1.1e-05 24.9 2.1 1.8 1 1 1 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 KXZ55568.1 - 3.3e-05 23.1 3.9 0.035 13.1 0.8 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXZ55569.1 - 2.2e-22 79.6 6.3 2.2e-22 79.6 6.3 1.5 1 1 0 1 1 1 1 Citrate transporter ADH_zinc_N PF00107.26 KXZ55570.1 - 6.3e-24 84.4 1.7 8.6e-24 84.0 1.7 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXZ55570.1 - 9.7e-18 65.5 1.1 1.5e-17 64.8 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXZ55570.1 - 2.5e-08 33.8 0.2 4.2e-07 29.8 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXZ55570.1 - 0.035 13.6 1.5 0.053 13.0 1.5 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 KXZ55570.1 - 0.16 11.7 1.7 0.41 10.4 1.7 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_1 PF00561.20 KXZ55572.1 - 2.2e-06 27.5 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ55572.1 - 0.016 14.4 0.1 0.79 8.9 0.1 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 AXE1 PF05448.12 KXZ55572.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) FAM176 PF14851.6 KXZ55573.1 - 0.19 11.4 0.1 0.45 10.2 0.1 1.5 1 0 0 1 1 1 0 FAM176 family HTH_9 PF08221.11 KXZ55574.1 - 4.6e-17 61.9 0.2 1e-11 44.7 0.0 3.6 3 1 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KXZ55574.1 - 8.6e-10 38.8 0.0 6.9e-07 29.3 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 HTH_IclR PF09339.10 KXZ55574.1 - 0.00021 21.0 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain MetOD2 PF18548.1 KXZ55574.1 - 0.027 14.6 0.2 0.071 13.2 0.2 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 TRAPPC-Trs85 PF12739.7 KXZ55574.1 - 0.099 11.6 0.2 0.17 10.8 0.2 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Chloroa_b-bind PF00504.21 KXZ55575.1 - 6e-46 156.9 0.0 7.7e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RIBIOP_C PF04950.12 KXZ55576.1 - 2.1e-54 185.0 0.0 2.3e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PEPcase PF00311.17 KXZ55577.1 - 3.9e-08 31.9 0.5 5.8e-08 31.3 0.5 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase FTA4 PF13093.6 KXZ55577.1 - 0.0017 18.3 0.3 0.0018 18.2 0.3 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PEPcase PF00311.17 KXZ55578.1 - 1.5e-110 370.6 0.8 3.3e-70 237.2 0.0 2.0 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase TMEM189_B_dmain PF10520.9 KXZ55581.1 - 7.3e-64 215.0 0.2 1e-63 214.6 0.2 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 KXZ55581.1 - 0.00012 22.4 3.0 0.00018 21.9 2.3 1.5 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily UPF0014 PF03649.13 KXZ55582.1 - 1.7e-56 191.3 25.7 2.5e-54 184.2 25.7 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0014) IF-2B PF01008.17 KXZ55583.1 - 1.7e-68 230.9 0.0 2.2e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family APH PF01636.23 KXZ55583.1 - 3e-21 76.5 0.4 6.4e-21 75.4 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 KXZ55583.1 - 9.9e-05 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Choline_kinase PF01633.20 KXZ55583.1 - 0.055 13.1 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase E2F_TDP PF02319.20 KXZ55584.1 - 0.0065 16.5 0.0 0.078 13.0 0.0 2.1 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Actin PF00022.19 KXZ55585.1 - 4.8e-95 318.6 0.0 1.5e-60 204.9 0.0 3.4 1 1 1 2 2 2 2 Actin BACK PF07707.15 KXZ55586.1 - 3.4e-05 23.9 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch LPAM_1 PF08139.12 KXZ55588.1 - 0.22 12.1 1.0 0.52 10.9 0.2 2.0 1 1 1 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site MFS_1 PF07690.16 KXZ55589.1 - 6.1e-20 71.4 54.0 1.4e-15 57.1 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GBP PF02263.19 KXZ55590.1 - 3.7e-44 150.9 0.0 3.5e-26 92.0 0.0 2.3 1 1 1 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KXZ55590.1 - 1.5e-23 83.6 3.0 4.3e-23 82.2 3.0 1.7 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain SBP_bac_8 PF13416.6 KXZ55590.1 - 1.9e-09 37.7 0.0 6.1e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Guanylate_cyc PF00211.20 KXZ55590.1 - 1.1e-06 28.4 0.0 0.0048 16.5 0.0 2.7 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain SBP_bac_1 PF01547.25 KXZ55590.1 - 1.4e-06 28.5 0.0 4.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein adh_short PF00106.25 KXZ55591.1 - 5.7e-30 104.2 0.7 5.3e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ55591.1 - 4.5e-29 101.7 1.2 6.3e-28 97.9 0.1 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KXZ55591.1 - 3.7e-28 98.1 2.5 4e-27 94.7 0.1 2.8 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXZ55591.1 - 2.5e-21 77.1 0.3 1.2e-20 74.9 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXZ55591.1 - 0.00016 21.5 0.2 0.00042 20.2 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KXZ55591.1 - 0.014 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Nitro_FeMo-Co PF02579.17 KXZ55591.1 - 0.082 13.2 0.4 0.4 11.0 0.4 2.2 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor mTERF PF02536.14 KXZ55592.1 - 0.037 12.9 0.0 0.098 11.6 0.0 1.6 2 0 0 2 2 2 0 mTERF DUF1997 PF09366.10 KXZ55593.1 - 6.1e-25 88.2 0.0 7.7e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) Guanylate_cyc PF00211.20 KXZ55594.1 - 1.4e-23 83.5 0.0 5.4e-11 42.5 0.1 2.8 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SBP_bac_1 PF01547.25 KXZ55594.1 - 2e-07 31.3 0.1 4.9e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KXZ55594.1 - 1.4e-05 25.0 0.0 0.00015 21.6 0.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein DUF1685 PF07939.11 KXZ55594.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) NTPase_1 PF03266.15 KXZ55595.1 - 4.7e-07 29.9 0.4 0.038 13.9 0.0 2.3 2 0 0 2 2 2 2 NTPase AAA PF00004.29 KXZ55595.1 - 2.5e-06 27.9 0.0 5.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXZ55595.1 - 1.6e-05 24.7 2.2 1.6e-05 24.7 2.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXZ55595.1 - 2.7e-05 24.0 0.0 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXZ55595.1 - 0.00025 21.1 0.1 0.00069 19.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ55595.1 - 0.00056 20.2 0.1 0.002 18.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ55595.1 - 0.0006 20.4 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXZ55595.1 - 0.0025 18.2 0.5 0.011 16.1 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain T2SSE PF00437.20 KXZ55595.1 - 0.0056 15.8 1.5 0.011 14.8 1.5 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2325 PF10087.9 KXZ55595.1 - 0.0063 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) AAA_25 PF13481.6 KXZ55595.1 - 0.017 14.7 0.2 0.35 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXZ55595.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 KXZ55595.1 - 0.044 13.9 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) SRP54 PF00448.22 KXZ55595.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KdpD PF02702.17 KXZ55595.1 - 0.056 12.9 1.2 0.18 11.2 0.3 2.0 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain TniB PF05621.11 KXZ55595.1 - 0.058 12.8 0.1 0.48 9.8 0.1 2.3 1 1 0 1 1 1 0 Bacterial TniB protein AAA_19 PF13245.6 KXZ55595.1 - 0.06 13.7 0.1 0.18 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 KXZ55595.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_31 PF13614.6 KXZ55595.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ55595.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.10 KXZ55595.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TrwB_AAD_bind PF10412.9 KXZ55595.1 - 0.19 10.6 0.1 0.41 9.5 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UAA PF08449.11 KXZ55596.1 - 7.6e-54 182.9 14.5 9.4e-54 182.6 14.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXZ55596.1 - 1.2e-07 32.0 29.4 2.2e-05 24.6 13.9 2.6 3 0 0 3 3 3 2 EamA-like transporter family 4HBT PF03061.22 KXZ55597.1 - 1.7e-06 28.3 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DNA_pol3_chi PF04364.13 KXZ55598.1 - 1.9e-05 24.8 0.1 0.42 10.8 0.0 3.0 2 0 0 2 2 2 2 DNA polymerase III chi subunit, HolC Fringe PF02434.16 KXZ55598.1 - 0.00087 18.8 0.6 3.3 7.1 0.0 3.1 3 0 0 3 3 3 2 Fringe-like DUF604 PF04646.12 KXZ55598.1 - 0.0059 16.0 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Zn_Tnp_IS1595 PF12760.7 KXZ55598.1 - 1.8 8.6 7.6 15 5.7 1.0 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Rep_fac-A_3 PF08661.11 KXZ55599.1 - 2.2e-08 34.4 0.1 2.7e-08 34.1 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF3104 PF11302.8 KXZ55599.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Aldose_epim PF01263.20 KXZ55600.1 - 5e-49 167.2 0.0 5.7e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase APS_kinase PF01583.20 KXZ55601.1 - 9.3e-71 236.8 0.0 1.2e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KXZ55601.1 - 5.8e-06 26.5 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KXZ55601.1 - 4.3e-05 23.6 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KXZ55601.1 - 0.00096 18.7 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase KTI12 PF08433.10 KXZ55601.1 - 0.0011 18.4 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 KXZ55601.1 - 0.0027 17.4 0.8 0.0067 16.1 0.4 1.8 1 1 1 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KXZ55601.1 - 0.0039 17.7 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KXZ55601.1 - 0.0039 17.6 0.1 0.0056 17.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXZ55601.1 - 0.0071 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 KXZ55601.1 - 0.0094 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KXZ55601.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXZ55601.1 - 0.011 16.2 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 KXZ55601.1 - 0.025 13.8 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_25 PF13481.6 KXZ55601.1 - 0.027 14.1 0.1 0.041 13.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KXZ55601.1 - 0.034 13.1 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KXZ55601.1 - 0.036 14.0 0.2 0.062 13.2 0.2 1.3 1 0 0 1 1 1 0 NACHT domain SWI2_SNF2 PF18766.1 KXZ55601.1 - 0.039 13.6 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase PRK PF00485.18 KXZ55601.1 - 0.042 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KXZ55601.1 - 0.061 13.7 0.0 0.093 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase LCM PF04072.14 KXZ55602.1 - 2e-19 70.3 0.0 1.7e-17 64.0 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase SBP_bac_8 PF13416.6 KXZ55603.1 - 7.6e-12 45.6 2.0 3.4e-11 43.5 0.0 2.9 3 1 1 4 4 4 1 Bacterial extracellular solute-binding protein Guanylate_cyc PF00211.20 KXZ55603.1 - 1.4e-11 44.3 0.0 1.5e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SBP_bac_1 PF01547.25 KXZ55603.1 - 9.9e-09 35.6 0.7 2.8e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein RhoGAP PF00620.27 KXZ55604.1 - 1.7e-07 31.2 0.0 2.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Fringe PF02434.16 KXZ55605.1 - 5.2e-05 22.8 0.1 0.00012 21.6 0.1 1.5 1 1 0 1 1 1 1 Fringe-like Pkinase_Tyr PF07714.17 KXZ55606.1 - 0.092 12.0 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KXZ55607.1 - 4.7e-14 52.4 0.0 4.2e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55607.1 - 1e-11 44.6 0.0 6.8e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DNA_processg_A PF02481.15 KXZ55608.1 - 0.00081 18.7 0.0 0.00087 18.6 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DUF4469 PF14734.6 KXZ55608.1 - 0.071 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold Adaptin_N PF01602.20 KXZ55609.1 - 5.3e-130 434.5 0.0 6.3e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KXZ55609.1 - 3e-25 88.7 0.5 5.5e-25 87.8 0.5 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KXZ55609.1 - 5.9e-11 42.7 1.2 1.7e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXZ55609.1 - 0.0055 17.1 15.1 0.36 11.2 0.4 4.9 3 1 1 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KXZ55609.1 - 0.018 15.6 0.7 5.8 7.6 0.2 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 KXZ55609.1 - 0.23 11.6 0.2 1.7 8.8 0.2 2.4 1 1 0 1 1 1 0 V-ATPase subunit H MTHFR PF02219.17 KXZ55610.1 - 0.054 12.8 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase Peptidase_S9 PF00326.21 KXZ55612.1 - 3.2e-05 23.5 0.2 0.0012 18.4 0.0 2.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 KXZ55612.1 - 0.00095 18.8 0.0 0.0088 15.6 0.0 2.5 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 KXZ55612.1 - 0.0014 17.3 0.0 0.0054 15.4 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KXZ55612.1 - 0.06 12.9 0.1 0.06 12.9 0.1 3.3 4 0 0 4 4 4 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_7 PF12715.7 KXZ55612.1 - 0.3 10.3 0.0 0.94 8.6 0.0 1.8 1 0 0 1 1 1 0 Abhydrolase family HSP70 PF00012.20 KXZ55613.1 - 6.1e-151 503.6 0.0 1e-150 502.9 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ55613.1 - 6.5e-08 31.8 0.1 1.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PRIMA1 PF16101.5 KXZ55613.1 - 4.8 7.2 7.8 11 6.0 7.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4461 PF14688.6 KXZ55614.1 - 7.8e-50 170.4 0.0 1.1e-49 170.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) AAA PF00004.29 KXZ55616.1 - 1.2e-05 25.8 1.4 3.1e-05 24.4 0.2 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ55616.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXZ55616.1 - 0.035 14.3 0.1 0.07 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXZ55616.1 - 0.05 13.4 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KXZ55616.1 - 0.068 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXZ55616.1 - 0.079 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXZ55616.1 - 0.081 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KXZ55616.1 - 0.11 12.8 2.1 0.14 12.5 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KXZ55616.1 - 0.15 11.6 3.0 0.17 11.5 0.2 2.5 1 1 2 3 3 3 0 AAA domain ATPase PF06745.13 KXZ55616.1 - 0.19 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 KXZ55616.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DEAD PF00270.29 KXZ55618.1 - 5.1e-50 169.7 0.0 1.5e-49 168.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ55618.1 - 4.4e-25 88.2 0.0 9e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ55618.1 - 0.001 19.1 0.0 0.0056 16.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Hydrolase_4 PF12146.8 KXZ55618.1 - 0.11 11.7 2.3 0.69 9.1 2.7 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Methyltrans_SAM PF10672.9 KXZ55619.1 - 3e-16 59.4 0.0 4.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 KXZ55619.1 - 6.2e-14 52.1 0.0 1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PUA_3 PF17785.1 KXZ55619.1 - 3.1e-11 42.9 0.0 6.6e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain Cons_hypoth95 PF03602.15 KXZ55619.1 - 1.9e-10 40.6 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KXZ55619.1 - 2.3e-09 37.8 0.0 5.5e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXZ55619.1 - 5.7e-09 35.8 0.4 9.5e-09 35.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXZ55619.1 - 4.6e-07 29.5 0.0 7.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KXZ55619.1 - 2.8e-06 27.0 0.0 4.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 KXZ55619.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KXZ55619.1 - 0.00013 21.9 0.0 0.0004 20.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ55619.1 - 0.00038 21.0 1.2 0.0015 19.1 0.1 2.6 3 0 0 3 3 2 1 Methyltransferase domain UPF0113 PF03657.13 KXZ55619.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain ADH_zinc_N PF00107.26 KXZ55619.1 - 0.001 19.0 1.9 0.0015 18.5 0.2 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Met_10 PF02475.16 KXZ55619.1 - 0.0024 17.6 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein UPF0020 PF01170.18 KXZ55619.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltr_RsmB-F PF01189.17 KXZ55619.1 - 0.026 14.2 0.1 0.13 11.8 0.1 2.0 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_12 PF08242.12 KXZ55619.1 - 0.052 14.3 0.3 0.17 12.6 0.1 2.0 2 0 0 2 2 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ55619.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family N6_Mtase PF02384.16 KXZ55619.1 - 0.28 10.4 0.0 0.41 9.9 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase HMG_CoA_synt_N PF01154.17 KXZ55620.1 - 3.5e-35 121.4 2.0 6.9e-22 78.1 1.6 2.6 2 1 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KXZ55620.1 - 4.2e-30 105.3 0.0 1.9e-13 50.7 0.0 3.1 3 0 0 3 3 3 3 Hydroxymethylglutaryl-coenzyme A synthase C terminal PsbP PF01789.16 KXZ55621.1 - 2.6e-23 82.9 0.0 3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 PsbP PIN_10 PF18478.1 KXZ55622.1 - 0.11 12.7 1.1 0.44 10.8 0.1 2.5 2 0 0 2 2 2 0 PIN like domain ATG16 PF08614.11 KXZ55623.1 - 0.0024 18.1 3.9 0.0024 18.1 3.9 1.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CCDC85 PF10226.9 KXZ55623.1 - 0.016 14.9 4.5 0.025 14.3 3.9 1.6 1 1 0 1 1 1 0 CCDC85 family SIKE PF05769.11 KXZ55623.1 - 0.023 14.6 6.0 0.18 11.8 0.9 2.2 1 1 1 2 2 2 0 SIKE family APG6_N PF17675.1 KXZ55623.1 - 0.04 14.5 7.6 0.062 13.8 7.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Adaptin_binding PF10199.9 KXZ55623.1 - 0.04 14.5 3.1 0.087 13.4 3.1 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 UPF0242 PF06785.11 KXZ55623.1 - 0.047 13.8 2.9 0.064 13.4 2.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NuiA PF07924.11 KXZ55623.1 - 0.15 12.5 0.9 0.24 11.8 0.9 1.3 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein H-kinase_dim PF02895.14 KXZ55623.1 - 1.3 9.4 4.7 2.5 8.5 4.7 1.4 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF563 PF04577.14 KXZ55624.1 - 5.3e-19 69.2 0.1 7.4e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Trigger_C PF05698.14 KXZ55624.1 - 0.24 11.4 0.0 0.42 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Response_reg PF00072.24 KXZ55625.1 - 4.5e-16 59.0 0.0 8.7e-16 58.1 0.0 1.4 1 1 0 1 1 1 1 Response regulator receiver domain AAA PF00004.29 KXZ55626.1 - 3.3e-48 163.4 0.0 3.1e-36 124.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KXZ55626.1 - 3.8e-21 75.3 0.1 6.6e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 KXZ55626.1 - 3.9e-09 37.1 13.2 1.8e-05 25.2 0.2 4.6 3 1 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.17 KXZ55626.1 - 1.1e-06 28.5 0.0 0.055 13.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 KXZ55626.1 - 4.2e-05 23.8 0.2 0.36 11.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXZ55626.1 - 0.0011 18.9 0.0 0.32 11.0 0.0 2.9 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KXZ55626.1 - 0.0023 17.8 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXZ55626.1 - 0.0054 16.7 0.2 3.1 7.7 0.0 3.6 3 1 0 3 3 3 1 NACHT domain AAA_lid_3 PF17862.1 KXZ55626.1 - 0.0058 16.4 5.4 0.12 12.2 0.2 3.3 3 0 0 3 3 3 1 AAA+ lid domain AAA_29 PF13555.6 KXZ55626.1 - 0.013 15.2 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain CDC48_2 PF02933.17 KXZ55626.1 - 0.017 14.9 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.6 KXZ55626.1 - 0.018 15.4 0.4 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KXZ55626.1 - 0.032 14.0 0.0 8.3 6.1 0.0 3.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Ploopntkinase3 PF18751.1 KXZ55626.1 - 0.038 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 KXZ55626.1 - 0.052 13.3 5.7 0.77 9.4 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KXZ55626.1 - 0.061 13.9 0.0 16 6.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXZ55626.1 - 0.065 13.6 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 KXZ55626.1 - 1.4 8.5 11.1 0.16 11.6 1.0 3.5 3 1 0 3 3 3 0 AAA domain Arm PF00514.23 KXZ55627.1 - 0.0063 16.5 2.1 0.16 12.1 0.0 3.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DLH PF01738.18 KXZ55628.1 - 4.7e-10 39.4 1.8 2.1e-09 37.3 0.2 2.0 1 1 1 2 2 2 2 Dienelactone hydrolase family CH PF00307.31 KXZ55629.1 - 2.7e-22 79.0 0.0 5.1e-08 33.1 0.0 3.6 3 1 0 3 3 3 3 Calponin homology (CH) domain LRR_9 PF14580.6 KXZ55630.1 - 3.4e-52 176.5 1.2 5.1e-52 175.9 1.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KXZ55630.1 - 7.6e-10 38.9 11.6 3.4e-05 24.1 4.8 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ55630.1 - 3.9e-05 23.3 10.0 0.00075 19.2 7.3 3.0 2 1 1 3 3 3 2 Leucine rich repeat Gal11_ABD1 PF18535.1 KXZ55630.1 - 0.072 13.2 0.5 0.18 11.9 0.2 1.7 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) DUF3557 PF12078.8 KXZ55630.1 - 0.1 12.6 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Serpin PF00079.20 KXZ55631.1 - 7.1e-65 219.7 0.0 8e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KXZ55632.1 - 5.8e-77 259.5 0.0 7.2e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KXZ55633.1 - 5e-15 55.7 0.0 5.9e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KXZ55634.1 - 6.5e-41 140.9 0.0 6.1e-39 134.4 0.0 2.0 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) L51_S25_CI-B8 PF05047.16 KXZ55635.1 - 7e-13 48.3 0.0 8.9e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Fcf1 PF04900.12 KXZ55636.1 - 8.6e-40 135.1 4.9 1.1e-39 134.8 4.9 1.1 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KXZ55636.1 - 3.9e-13 49.7 0.0 6.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 PIN like domain DUF1923 PF09083.10 KXZ55636.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) DUF4179 PF13786.6 KXZ55637.1 - 0.73 10.3 6.5 4 8.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Chloroa_b-bind PF00504.21 KXZ55639.1 - 5.1e-10 40.1 3.8 6.4e-05 23.5 0.5 2.0 1 1 1 2 2 2 2 Chlorophyll A-B binding protein BACK PF07707.15 KXZ55640.1 - 3.2e-06 27.2 0.0 8.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch DGC PF08859.11 KXZ55640.1 - 0.013 15.5 0.1 0.031 14.4 0.1 1.6 1 0 0 1 1 1 0 DGC domain BTB PF00651.31 KXZ55640.1 - 0.067 13.4 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain DNA_pol3_delta2 PF13177.6 KXZ55641.1 - 3.4e-09 36.7 0.0 1.2e-07 31.7 0.0 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KXZ55641.1 - 5.9e-06 26.7 0.2 2.5e-05 24.7 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ55641.1 - 0.00018 21.5 0.1 0.0008 19.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rep_fac_C PF08542.11 KXZ55641.1 - 0.00018 21.8 0.1 0.00041 20.7 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 KXZ55641.1 - 0.00076 19.9 0.2 0.01 16.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXZ55641.1 - 0.0011 18.8 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 KXZ55641.1 - 0.0057 16.8 0.0 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KXZ55641.1 - 0.0092 15.4 0.1 0.75 9.1 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KXZ55641.1 - 0.021 15.1 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXZ55641.1 - 0.025 15.1 0.0 0.043 14.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KXZ55641.1 - 0.028 14.9 0.0 0.047 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXZ55641.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KXZ55641.1 - 0.13 12.4 0.3 0.46 10.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain XRN_N PF03159.18 KXZ55642.1 - 2.5e-101 338.2 0.6 3.4e-101 337.7 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KXZ55642.1 - 8.5e-40 137.0 0.2 4.4e-39 134.7 0.0 1.9 2 0 0 2 2 2 1 Xrn1 helical domain Nsp1_C PF05064.13 KXZ55643.1 - 2.1e-19 69.5 0.1 3.6e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KXZ55643.1 - 3.1e-05 24.7 97.8 0.00011 23.0 25.3 4.9 1 1 1 3 3 3 2 Nucleoporin FG repeat region DUF4515 PF14988.6 KXZ55643.1 - 0.19 11.6 0.1 0.3 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) PAPA-1 PF04795.12 KXZ55644.1 - 0.015 16.1 0.1 0.018 15.8 0.1 1.3 1 0 0 1 1 1 0 PAPA-1-like conserved region VPS11_C PF12451.8 KXZ55644.1 - 6.1 7.2 5.1 7.5 6.9 4.5 1.5 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal PWI PF01480.17 KXZ55645.1 - 1.4e-21 76.6 0.1 2.5e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 PWI domain RloB PF13707.6 KXZ55645.1 - 0.032 14.4 5.9 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 RloB-like protein RETICULATA-like PF11891.8 KXZ55646.1 - 2.6e-60 203.3 0.5 3.5e-60 202.9 0.0 1.4 2 0 0 2 2 2 1 Protein RETICULATA-related Guanylate_cyc PF00211.20 KXZ55647.1 - 4.5e-05 23.1 0.0 0.00012 21.8 0.0 1.6 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SBP_bac_8 PF13416.6 KXZ55648.1 - 2.1e-09 37.6 0.0 4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KXZ55648.1 - 5.1e-06 26.7 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein VPS28 PF03997.12 KXZ55649.1 - 3.4e-59 199.7 0.0 4.2e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Stealth_CR4 PF17103.5 KXZ55649.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Glyoxalase_2 PF12681.7 KXZ55650.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Pox_A14 PF05767.12 KXZ55651.1 - 0.0073 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 ABC2_membrane_2 PF12679.7 KXZ55651.1 - 1.2 8.4 5.2 1.6 7.9 5.2 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein EF-hand_7 PF13499.6 KXZ55653.1 - 1.3e-14 54.3 0.1 8.5e-10 39.0 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXZ55653.1 - 4.1e-12 45.0 0.0 3.2e-05 23.5 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KXZ55653.1 - 1.1e-11 43.4 0.7 6.8e-05 22.1 0.0 3.4 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KXZ55653.1 - 4.9e-08 32.7 0.1 1.7e-05 24.6 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ55653.1 - 3.9e-05 22.9 1.9 0.011 15.2 0.0 3.4 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 KXZ55653.1 - 0.062 13.6 0.0 0.29 11.5 0.0 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TonB_C PF03544.14 KXZ55653.1 - 0.064 13.7 0.0 1.2 9.6 0.0 2.6 3 0 0 3 3 3 0 Gram-negative bacterial TonB protein C-terminal Sigma70_r1_1 PF03979.14 KXZ55653.1 - 0.096 12.8 0.1 0.32 11.1 0.1 1.8 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF5580 PF17743.1 KXZ55653.1 - 0.15 10.6 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) WD40 PF00400.32 KXZ55654.1 - 1.3e-09 38.5 0.2 0.7 10.9 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55654.1 - 0.018 15.4 0.0 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_21 PF13506.6 KXZ55655.1 - 0.054 13.0 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 PDEase_I PF00233.19 KXZ55656.1 - 6e-53 180.0 0.0 8.7e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CcmD PF04995.14 KXZ55656.1 - 0.04 14.0 2.6 0.095 12.8 2.6 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Guanylate_cyc PF00211.20 KXZ55658.1 - 2e-66 223.1 0.1 2.7e-45 154.2 0.0 2.1 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Lactamase_B PF00753.27 KXZ55658.1 - 0.08 12.9 1.0 0.84 9.6 0.2 2.6 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily ACBP PF00887.19 KXZ55658.1 - 0.1 12.8 0.0 25 5.2 0.0 2.4 2 0 0 2 2 2 0 Acyl CoA binding protein SepF PF04472.12 KXZ55658.1 - 0.14 12.5 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Cell division protein SepF Pro_Al_protease PF02983.14 KXZ55658.1 - 0.72 10.0 6.2 12 6.0 0.1 3.3 3 0 0 3 3 3 0 Alpha-lytic protease prodomain PSI_8 PF00796.18 KXZ55658.1 - 3.3 7.6 5.1 33 4.4 0.4 2.6 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII Guanylate_cyc PF00211.20 KXZ55659.1 - 9.1e-65 217.7 0.1 4e-44 150.4 0.0 2.3 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain OSCP PF00213.18 KXZ55661.1 - 1.7e-28 99.9 2.0 2.4e-28 99.4 2.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit AcetDehyd-dimer PF09290.11 KXZ55661.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF4145 PF13643.6 KXZ55662.1 - 0.00043 20.4 0.1 0.00095 19.2 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4145) LRR_4 PF12799.7 KXZ55663.1 - 0.24 11.9 4.5 7.9 7.1 0.0 4.3 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF1043 PF06295.12 KXZ55664.1 - 2.7 8.0 6.2 4.9 7.2 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) ADIP PF11559.8 KXZ55664.1 - 3.3 7.8 9.2 6.1 6.9 9.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3700 PF12481.8 KXZ55665.1 - 2.8e-17 62.9 0.0 1.3e-15 57.5 0.0 2.1 2 0 0 2 2 2 2 Aluminium induced protein GATase_7 PF13537.6 KXZ55665.1 - 4.5e-13 49.2 0.0 1.8e-12 47.3 0.0 2.1 1 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXZ55665.1 - 1.1e-08 35.4 0.0 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain PAS_9 PF13426.7 KXZ55666.1 - 5.2e-08 33.1 0.0 3.1e-05 24.1 0.0 3.5 4 0 0 4 4 4 1 PAS domain PAS_4 PF08448.10 KXZ55666.1 - 5.4e-06 26.6 0.0 0.075 13.3 0.0 4.5 4 0 0 4 4 4 2 PAS fold PAS PF00989.25 KXZ55666.1 - 6.9e-06 26.0 0.0 0.023 14.7 0.0 4.8 6 0 0 6 6 6 1 PAS fold DUF1957 PF09210.11 KXZ55666.1 - 0.048 14.1 0.2 0.16 12.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Holin_BhlA PF10960.8 KXZ55666.1 - 0.16 11.9 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 BhlA holin family PAS_9 PF13426.7 KXZ55668.1 - 7.6e-09 35.8 0.0 8.8e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KXZ55668.1 - 6.6e-05 22.9 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KXZ55668.1 - 0.0025 18.0 0.0 0.33 11.2 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KXZ55668.1 - 0.0092 16.2 0.0 6.9 7.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold APG12 PF04110.13 KXZ55668.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 FAST_1 PF06743.15 KXZ55669.1 - 3e-07 30.3 0.6 0.045 13.7 0.2 4.5 5 1 1 6 6 6 3 FAST kinase-like protein, subdomain 1 RNA_pol_Rpb1_5 PF04998.17 KXZ55670.1 - 9.5e-103 343.3 0.0 1.7e-102 342.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KXZ55670.1 - 1.1e-95 320.6 0.0 2e-95 319.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KXZ55670.1 - 1.7e-69 233.3 0.1 4.6e-69 231.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KXZ55670.1 - 2.9e-55 187.1 0.0 6.4e-55 186.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KXZ55670.1 - 4.6e-50 169.6 0.0 1.7e-49 167.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXZ55670.1 - 2.7e-38 130.2 0.6 7.3e-38 128.8 0.3 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 KXZ55670.1 - 1.4e-31 109.3 0.4 3.2e-31 108.1 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 His_Phos_1 PF00300.22 KXZ55671.1 - 0.00048 19.9 0.1 0.00064 19.5 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ETC_C1_NDUFA4 PF04800.12 KXZ55673.1 - 3.2e-26 91.4 0.9 3.9e-26 91.1 0.9 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region EF-hand_7 PF13499.6 KXZ55674.1 - 6.8e-13 48.9 2.1 1.2e-12 48.1 0.2 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ55674.1 - 1.9e-12 45.8 1.3 4.2e-05 22.8 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXZ55674.1 - 4e-09 35.7 0.2 9.7e-05 22.0 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KXZ55674.1 - 1.6e-07 31.1 2.8 0.0001 22.0 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXZ55674.1 - 2.2e-07 30.0 1.4 0.0029 17.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KXZ55674.1 - 0.00022 21.5 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain DUF2630 PF10944.8 KXZ55674.1 - 0.15 12.5 5.8 0.38 11.2 5.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Phosphoprotein PF00922.17 KXZ55675.1 - 0.004 16.8 2.0 0.004 16.8 2.0 2.0 2 0 0 2 2 2 1 Vesiculovirus phosphoprotein LAX PF15681.5 KXZ55675.1 - 0.12 11.2 7.9 0.2 10.5 7.9 1.4 1 0 0 1 1 1 0 Lymphocyte activation family X Mem_trans PF03547.18 KXZ55676.1 - 5.6e-16 57.9 2.3 2.2e-08 32.9 3.6 2.1 1 1 1 2 2 2 2 Membrane transport protein Osw5 PF17062.5 KXZ55676.1 - 0.57 10.3 3.6 3.6 7.8 0.6 2.8 2 0 0 2 2 2 0 Outer spore wall 5 E1-E2_ATPase PF00122.20 KXZ55677.1 - 2.5e-42 144.5 0.7 2.5e-42 144.5 0.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXZ55677.1 - 9.5e-35 119.9 0.4 9.5e-35 119.9 0.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXZ55677.1 - 1.5e-19 71.1 1.1 2e-18 67.5 1.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ55677.1 - 1.7e-17 63.3 0.0 3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXZ55677.1 - 4.6e-06 26.6 0.4 0.00017 21.4 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXZ55677.1 - 3.5e-05 23.4 0.5 0.00019 21.0 0.5 2.2 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 KXZ55677.1 - 0.031 14.7 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ins134_P3_kin PF05770.11 KXZ55678.1 - 8.2e-11 41.8 0.0 6.8e-09 35.5 0.0 2.1 1 1 1 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain SecY PF00344.20 KXZ55679.1 - 1.3e-91 307.1 1.7 1.7e-91 306.7 1.7 1.1 1 0 0 1 1 1 1 SecY translocase UPRTase PF14681.6 KXZ55679.1 - 3.4e-61 206.3 0.0 6.1e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 KXZ55679.1 - 3.6e-47 160.7 0.1 6.1e-47 159.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KXZ55679.1 - 5.1e-06 27.1 0.0 1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXZ55679.1 - 2.3e-05 23.8 0.0 6.9e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin Pribosyltran PF00156.27 KXZ55679.1 - 0.00055 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AAA_33 PF13671.6 KXZ55679.1 - 0.00078 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 KXZ55679.1 - 0.012 15.3 0.4 0.041 13.6 0.4 1.9 1 1 0 1 1 1 0 Dephospho-CoA kinase AAA_17 PF13207.6 KXZ55679.1 - 0.014 15.8 0.1 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 KXZ55679.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 KXZ55679.1 - 0.019 14.7 0.1 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 KXZ55679.1 - 0.038 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein adh_short_C2 PF13561.6 KXZ55681.1 - 4e-40 137.8 0.0 4.6e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ55681.1 - 5.3e-31 107.6 0.1 5.8e-31 107.5 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ55681.1 - 0.0003 20.7 0.0 0.00037 20.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KXZ55681.1 - 0.085 12.0 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Senescence PF06911.12 KXZ55683.1 - 0.0014 19.0 24.0 0.02 15.2 5.8 2.2 1 1 1 2 2 2 2 Senescence-associated protein TMP_2 PF06791.13 KXZ55683.1 - 0.0092 15.7 29.1 0.16 11.6 14.1 2.1 1 1 1 2 2 2 2 Prophage tail length tape measure protein ApoLp-III PF07464.11 KXZ55683.1 - 0.054 13.6 8.1 0.098 12.8 4.1 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 KXZ55683.1 - 0.14 10.1 0.0 0.15 9.9 0.0 1.0 1 0 0 1 1 1 0 Prominin Mitofilin PF09731.9 KXZ55683.1 - 0.19 10.5 20.6 0.21 10.4 20.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tape_meas_lam_C PF09718.10 KXZ55683.1 - 0.28 11.3 21.2 0.25 11.5 2.9 3.4 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.7 KXZ55683.1 - 0.3 11.6 24.5 1.8e+04 -7.2 24.5 3.4 1 1 0 1 1 1 0 YtxH-like protein Apolipoprotein PF01442.18 KXZ55683.1 - 0.48 10.3 19.9 1.3 8.9 19.9 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KXZ55683.1 - 1.8 9.2 35.1 8.2 7.1 8.6 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Phasin_2 PF09361.10 KXZ55683.1 - 3.1 8.1 23.9 1.9 8.8 9.8 2.3 1 1 1 2 2 2 0 Phasin protein BACK PF07707.15 KXZ55684.1 - 4.4e-13 49.2 0.1 1.4e-12 47.6 0.1 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch Ribosomal_S26e PF01283.19 KXZ55685.1 - 7.7e-48 161.4 10.2 8.7e-48 161.2 10.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e IBR PF01485.21 KXZ55686.1 - 1.6e-21 76.3 25.2 6.6e-12 45.5 7.7 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KXZ55686.1 - 0.0015 18.3 5.1 0.0015 18.3 5.1 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ55686.1 - 0.006 16.6 5.3 0.006 16.6 5.3 3.5 3 0 0 3 3 3 1 RING-type zinc-finger DUF349 PF03993.12 KXZ55686.1 - 0.037 14.3 0.8 0.037 14.3 0.8 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) DUF2612 PF11041.8 KXZ55686.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) TED PF08341.11 KXZ55686.1 - 0.46 10.9 2.4 14 6.1 0.2 2.5 1 1 0 2 2 2 0 Thioester domain zf-RING_2 PF13639.6 KXZ55686.1 - 4.3 7.7 37.9 0.76 10.2 11.0 3.8 3 0 0 3 3 3 0 Ring finger domain Occludin_ELL PF07303.13 KXZ55687.1 - 0.0068 17.1 0.1 0.11 13.2 0.1 2.0 2 0 0 2 2 2 1 Occludin homology domain Cytotoxic PF09000.10 KXZ55687.1 - 0.026 14.8 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Cytotoxic Transketolase_N PF00456.21 KXZ55687.1 - 0.039 12.9 0.1 0.051 12.5 0.1 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain SurA_N_3 PF13624.6 KXZ55687.1 - 0.04 13.7 0.8 0.053 13.3 0.8 1.3 1 0 0 1 1 1 0 SurA N-terminal domain ADIP PF11559.8 KXZ55687.1 - 0.076 13.1 1.9 0.11 12.6 1.3 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KXZ55687.1 - 0.14 12.5 4.3 0.2 12.0 4.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LRR_4 PF12799.7 KXZ55688.1 - 0.00012 22.4 0.0 0.37 11.3 0.0 4.1 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ55688.1 - 0.00015 21.4 1.5 0.17 11.7 0.0 4.2 5 0 0 5 5 5 1 Leucine rich repeat Guanylate_cyc PF00211.20 KXZ55689.1 - 8.7e-48 162.4 0.0 1.4e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF846 PF05832.12 KXZ55691.1 - 4.2e-21 75.4 15.4 1.5e-10 41.3 2.6 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF846) DUF2632 PF10943.8 KXZ55691.1 - 0.02 14.5 3.8 0.025 14.1 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) PDR_assoc PF08370.11 KXZ55691.1 - 4.1 7.2 9.3 9.4 6.1 3.5 2.5 1 1 1 2 2 2 0 Plant PDR ABC transporter associated WH2 PF02205.20 KXZ55692.1 - 2.8e-06 27.0 0.0 0.0045 16.8 0.0 2.2 2 0 0 2 2 2 2 WH2 motif Lactamase_B_2 PF12706.7 KXZ55695.1 - 1.8e-14 53.8 0.1 3.5e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain RMMBL PF07521.12 KXZ55695.1 - 4.9e-13 48.8 0.5 6.2e-11 42.1 0.1 2.9 3 0 0 3 3 3 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KXZ55695.1 - 4.4e-08 33.4 0.2 1.2e-07 31.9 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KXZ55695.1 - 0.0021 18.0 0.0 0.085 12.7 0.0 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KXZ55695.1 - 0.034 13.6 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Herpes_U34 PF04541.13 KXZ55695.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 EphA2_TM PF14575.6 KXZ55696.1 - 0.051 14.5 0.7 2.7 9.0 0.5 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KXZ55696.1 - 0.29 11.3 4.9 3.1 8.0 0.2 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator CLP_protease PF00574.23 KXZ55701.1 - 5.8e-51 173.0 0.0 7.8e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease TPP_enzyme_M_2 PF16582.5 KXZ55701.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate Ribosomal_S10 PF00338.22 KXZ55701.1 - 0.065 13.5 0.1 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e Rad9 PF04139.13 KXZ55702.1 - 4.4e-23 82.0 0.0 5.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 NTP_transferase PF00483.23 KXZ55703.1 - 1e-26 94.0 0.0 8.5e-26 91.0 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KXZ55703.1 - 0.015 15.0 5.5 0.059 13.1 0.2 3.1 3 0 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) Flavodoxin_1 PF00258.25 KXZ55705.1 - 1.1e-10 41.9 0.0 1.3e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin PALP PF00291.25 KXZ55706.1 - 8.9e-67 225.6 2.0 8.9e-67 225.6 2.0 4.8 3 1 2 5 5 5 1 Pyridoxal-phosphate dependent enzyme FAD_binding_1 PF00667.20 KXZ55706.1 - 6.1e-42 143.7 0.0 1.5e-41 142.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KXZ55706.1 - 9.8e-16 58.4 1.4 3.8e-15 56.5 0.0 2.7 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain DUF3147 PF11345.8 KXZ55706.1 - 0.065 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) adh_short PF00106.25 KXZ55707.1 - 4.9e-28 97.9 0.3 1.3e-27 96.5 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ55707.1 - 3.3e-17 62.8 0.0 6e-17 62.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ55707.1 - 1.5e-06 28.2 0.2 4e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 KR domain MBOAT_2 PF13813.6 KXZ55709.1 - 1.5e-10 41.2 0.2 0.00032 20.9 0.0 2.3 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family MBOAT PF03062.19 KXZ55709.1 - 0.064 12.6 1.5 3.2 7.0 0.0 2.3 2 1 0 2 2 2 0 MBOAT, membrane-bound O-acyltransferase family Kelch_4 PF13418.6 KXZ55710.1 - 4.8e-16 58.5 0.8 0.00012 22.0 0.1 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KXZ55710.1 - 1e-14 54.4 3.0 7.9e-05 22.8 0.2 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KXZ55710.1 - 1e-14 54.2 0.5 5.5e-05 23.3 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KXZ55710.1 - 2.1e-09 36.9 10.1 0.00012 21.9 0.1 5.6 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KXZ55710.1 - 3e-09 36.7 14.5 0.19 11.8 0.0 5.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KXZ55710.1 - 2.1e-08 33.6 10.2 1.8e-05 24.3 0.1 5.2 5 0 0 5 5 5 2 Kelch motif AAA_6 PF12774.7 KXZ55711.1 - 2.7e-159 529.4 0.0 1.4e-158 527.1 0.0 2.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXZ55711.1 - 2e-132 442.1 0.8 2e-132 442.1 0.8 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KXZ55711.1 - 1.3e-106 356.3 0.0 8.2e-106 353.7 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KXZ55711.1 - 4.6e-93 311.3 0.0 1.2e-92 309.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXZ55711.1 - 3.5e-86 287.9 0.1 1.1e-85 286.3 0.1 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KXZ55711.1 - 8.9e-77 256.7 0.0 4.3e-74 247.9 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KXZ55711.1 - 5.4e-58 195.4 0.0 1.6e-57 193.9 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXZ55711.1 - 1.2e-46 157.7 0.0 4.1e-44 149.5 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KXZ55711.1 - 5.5e-46 157.2 10.5 5.5e-46 157.2 10.5 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KXZ55711.1 - 1.5e-25 89.7 0.0 2.9e-13 50.0 0.0 2.9 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KXZ55711.1 - 1.8e-20 73.3 0.0 6.2e-07 29.5 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KXZ55711.1 - 1.2e-11 44.7 0.1 6.1e-11 42.4 0.1 2.2 1 1 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KXZ55711.1 - 1.7e-06 28.5 0.0 0.19 12.1 0.0 5.2 6 0 0 6 6 6 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXZ55711.1 - 7.5e-05 23.0 0.0 8.4 6.7 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 KXZ55711.1 - 9.1e-05 22.9 2.8 1.9 8.8 0.0 5.6 5 0 0 5 5 4 2 AAA ATPase domain AAA_30 PF13604.6 KXZ55711.1 - 0.00021 21.1 0.8 0.93 9.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.6 KXZ55711.1 - 0.00081 19.7 0.1 0.98 9.7 0.0 3.9 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 KXZ55711.1 - 0.00094 19.5 0.0 1.2 9.6 0.0 3.4 3 0 0 3 3 3 1 RNA helicase T2SSE PF00437.20 KXZ55711.1 - 0.0011 18.1 0.1 0.0073 15.4 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_33 PF13671.6 KXZ55711.1 - 0.0014 18.8 0.1 0.66 10.1 0.0 3.9 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 KXZ55711.1 - 0.0044 16.4 0.9 0.67 9.3 0.0 3.8 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXZ55711.1 - 0.0045 16.7 0.0 0.21 11.3 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 KXZ55711.1 - 0.0073 16.9 0.1 0.12 12.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KXZ55711.1 - 0.13 11.6 4.3 3.8 6.8 0.0 4.3 5 0 0 5 5 5 0 FtsK/SpoIIIE family PEARLI-4 PF05278.12 KXZ55711.1 - 1.7 8.1 5.0 3.9 7.0 5.0 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) SPATA1_C PF15743.5 KXZ55711.1 - 7.8 6.5 7.6 2.1 8.4 2.0 2.7 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Peptidase_S8 PF00082.22 KXZ55712.1 - 3.3e-18 66.0 1.2 3.3e-18 66.0 1.2 3.0 2 1 0 2 2 2 1 Subtilase family 4HBT PF03061.22 KXZ55714.1 - 8.4e-06 26.1 1.5 0.0017 18.6 0.1 2.9 2 1 0 2 2 2 2 Thioesterase superfamily Ribosomal_L32p PF01783.23 KXZ55714.1 - 0.52 10.6 3.7 1.4 9.2 3.7 1.7 1 0 0 1 1 1 0 Ribosomal L32p protein family WLM PF08325.10 KXZ55715.1 - 2e-33 116.1 0.0 4.6e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 WLM domain PUB PF09409.10 KXZ55715.1 - 4.6e-14 52.1 0.0 7.7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 PUB domain SprT-like PF10263.9 KXZ55715.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 SprT-like family SRP54 PF00448.22 KXZ55716.1 - 2e-54 184.2 0.2 7.8e-42 143.1 0.0 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 KXZ55716.1 - 1.1e-34 120.7 12.4 1.8e-33 116.7 12.4 2.0 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 KXZ55716.1 - 6.2e-05 22.1 0.0 0.00015 20.8 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KXZ55716.1 - 0.00016 22.0 0.0 0.00042 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54_N PF02881.19 KXZ55716.1 - 0.00024 21.3 0.0 0.00072 19.7 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KXZ55716.1 - 0.00069 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KXZ55716.1 - 0.0019 17.7 0.3 0.0046 16.4 0.3 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KXZ55716.1 - 0.013 14.7 0.2 0.024 13.8 0.2 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_31 PF13614.6 KXZ55716.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXZ55716.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXZ55716.1 - 0.021 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KXZ55716.1 - 0.021 14.9 0.1 0.064 13.3 0.1 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KXZ55716.1 - 0.021 14.7 0.3 7.2 6.5 0.1 2.4 1 1 0 2 2 2 0 NTPase AAA_23 PF13476.6 KXZ55716.1 - 0.027 15.0 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 KXZ55716.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RsgA_GTPase PF03193.16 KXZ55716.1 - 0.16 11.8 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase VirC1 PF07015.11 KXZ55716.1 - 0.17 11.2 0.0 0.49 9.7 0.0 1.7 1 1 0 1 1 1 0 VirC1 protein FXMRP1_C_core PF12235.8 KXZ55716.1 - 3.2 8.4 5.4 1.3 9.7 2.2 1.9 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal Pkinase_Tyr PF07714.17 KXZ55717.1 - 8.1e-07 28.6 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BPL_LplA_LipB PF03099.19 KXZ55719.1 - 1.1e-08 35.0 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MFS_1 PF07690.16 KXZ55720.1 - 1.9e-50 171.8 42.6 4e-49 167.4 33.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ55720.1 - 4.8e-08 32.3 2.0 4.8e-08 32.3 2.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXZ55720.1 - 3.4e-05 22.3 0.1 0.0016 16.9 0.0 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family RS4NT PF08071.12 KXZ55720.1 - 0.11 12.7 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 RS4NT (NUC023) domain bZIP_1 PF00170.21 KXZ55721.1 - 0.18 11.9 11.5 0.41 10.8 10.6 2.0 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 KXZ55721.1 - 1.4 9.1 8.7 3 8.0 7.5 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 KXZ55721.1 - 5.9 7.5 8.3 0.16 12.5 1.8 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Aldedh PF00171.22 KXZ55722.1 - 1.8e-13 49.9 0.1 2.1e-13 49.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family fn3_PAP PF17808.1 KXZ55722.1 - 0.14 12.2 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase WD40 PF00400.32 KXZ55724.1 - 2.4e-21 75.6 2.6 0.00014 22.6 0.0 8.4 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55724.1 - 1.7e-11 44.2 0.3 0.13 12.6 0.0 5.4 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXZ55724.1 - 0.00064 19.6 0.1 28 4.8 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat YL1 PF05764.13 KXZ55724.1 - 0.049 13.8 18.1 0.091 12.9 10.8 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Ge1_WD40 PF16529.5 KXZ55724.1 - 0.055 12.4 0.0 17 4.2 0.0 3.4 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Astro_capsid_p PF12226.8 KXZ55724.1 - 0.16 11.1 7.6 0.32 10.1 7.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HATPase_c_3 PF13589.6 KXZ55725.1 - 0.00028 20.7 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nop14 PF04147.12 KXZ55725.1 - 4.7 5.3 29.8 6.8 4.8 29.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KXZ55725.1 - 5.7 5.4 28.6 9.1 4.7 28.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 KXZ55725.1 - 6.6 6.1 30.1 11 5.3 30.1 1.2 1 0 0 1 1 1 0 SDA1 SET PF00856.28 KXZ55726.1 - 1.4e-12 48.3 0.0 1.7e-11 44.8 0.0 2.5 2 1 0 2 2 2 1 SET domain NUFIP1 PF10453.9 KXZ55726.1 - 0.081 12.8 1.2 0.15 11.9 1.2 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Orn_Arg_deC_N PF02784.16 KXZ55727.1 - 2.2e-28 99.3 0.0 8e-26 90.9 0.0 3.1 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXZ55727.1 - 1.1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain APH PF01636.23 KXZ55728.1 - 8.5e-41 140.5 0.1 8.5e-41 140.5 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 KXZ55728.1 - 2.2e-30 105.8 4.2 6.6e-30 104.3 4.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXZ55728.1 - 4.4e-15 55.6 0.1 7.9e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXZ55728.1 - 2.6e-07 31.3 9.0 7.9e-07 29.7 3.7 3.5 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXZ55728.1 - 3.6e-07 30.5 9.6 3.6e-07 30.5 9.6 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain RIO1 PF01163.22 KXZ55728.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KXZ55728.1 - 0.25 10.7 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 3-alpha PF03475.14 KXZ55729.1 - 0.022 14.6 1.4 12 5.9 0.0 4.2 3 0 0 3 3 3 0 3-alpha domain Hist_deacetyl PF00850.19 KXZ55731.1 - 6.7e-35 121.0 0.0 1e-34 120.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Hist_deacetyl PF00850.19 KXZ55732.1 - 1.7e-42 146.0 0.7 1.9e-42 145.8 0.7 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Hormone_3 PF00159.18 KXZ55732.1 - 0.024 14.7 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 Pancreatic hormone peptide Filamin PF00630.19 KXZ55733.1 - 8.4e-20 71.5 0.2 1.6e-19 70.6 0.2 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat RRM_1 PF00076.22 KXZ55733.1 - 3.7e-08 33.1 0.0 7.6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Invasin_D3 PF09134.10 KXZ55733.1 - 4.4e-07 30.1 0.1 2e-06 28.0 0.1 2.1 1 0 0 1 1 1 1 Invasin, domain 3 RRM_5 PF13893.6 KXZ55733.1 - 2.2e-05 24.0 0.1 5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YtkA PF13115.6 KXZ55733.1 - 0.013 16.0 0.1 0.013 16.0 0.1 2.2 3 0 0 3 3 3 0 YtkA-like RRM_occluded PF16842.5 KXZ55733.1 - 0.02 14.7 0.1 0.043 13.7 0.1 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif DUF2052 PF09747.9 KXZ55733.1 - 0.32 11.1 0.0 0.32 11.1 0.0 3.3 2 1 1 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DUF4378 PF14309.6 KXZ55734.1 - 7.1e-11 42.8 0.2 1.5e-10 41.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) AAA_7 PF12775.7 KXZ55735.1 - 0.00057 19.4 0.0 0.00078 19.0 0.0 1.3 1 1 0 1 1 1 1 P-loop containing dynein motor region EspB_PE PF18625.1 KXZ55735.1 - 0.092 13.2 6.0 2.1 8.8 6.0 2.8 1 1 0 1 1 1 0 ESX-1 secreted protein B PE domain Borrelia_P83 PF05262.11 KXZ55736.1 - 8 4.8 11.8 13 4.1 11.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein HMG_box PF00505.19 KXZ55737.1 - 3e-26 91.6 7.9 1.5e-15 57.4 1.1 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KXZ55737.1 - 1.9e-15 57.2 11.6 1.1e-08 35.5 2.7 2.7 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.12 KXZ55737.1 - 0.00024 21.0 0.2 0.023 14.6 0.1 2.3 2 0 0 2 2 2 1 CHDNT (NUC034) domain MlaC PF05494.12 KXZ55737.1 - 0.094 12.5 0.4 8.9 6.0 0.0 2.2 2 0 0 2 2 2 0 MlaC protein YABBY PF04690.13 KXZ55737.1 - 3.9 8.0 7.5 1.2 9.7 1.8 2.1 1 1 1 2 2 2 0 YABBY protein RTT107_BRCT_5 PF16770.5 KXZ55738.1 - 0.00092 19.1 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KXZ55738.1 - 0.032 14.6 0.0 0.071 13.5 0.0 1.6 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXZ55738.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 KXZ55739.1 - 1.2e-10 41.2 0.2 1.3e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55739.1 - 8.9e-06 25.2 0.3 9.9e-06 25.0 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase 4HBT_3 PF13622.6 KXZ55739.1 - 0.00076 19.8 0.0 0.00081 19.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.25 KXZ55740.1 - 2.3e-12 46.9 0.0 6.7e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55740.1 - 0.00058 19.2 0.0 0.0019 17.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 KXZ55741.1 - 3.3e-08 34.1 3.2 0.0086 16.9 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 KXZ55741.1 - 0.0008 19.3 0.1 1.8 8.4 0.0 3.1 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 KXZ55741.1 - 0.005 16.2 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ANAPC4_WD40 PF12894.7 KXZ55741.1 - 0.07 13.4 0.0 19 5.6 0.0 3.6 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 KXZ55742.1 - 1.8e-51 172.0 0.2 4e-18 65.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.29 KXZ55743.1 - 7.5e-41 137.8 0.0 1.7e-13 50.2 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXZ55743.1 - 1.1e-09 38.0 0.2 0.026 14.4 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXZ55743.1 - 9.8e-09 34.9 0.2 0.019 14.8 0.0 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KXZ55743.1 - 0.0015 18.5 0.0 0.024 14.6 0.0 2.5 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KXZ55743.1 - 0.042 13.9 1.2 10 6.3 0.0 3.1 3 0 0 3 3 3 0 NusA-like KH domain SLS PF14611.6 KXZ55743.1 - 0.063 13.1 0.2 0.39 10.5 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator NTP_transferase PF00483.23 KXZ55744.1 - 3.9e-52 177.3 0.0 4.9e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KXZ55744.1 - 3.2e-11 43.8 0.0 4.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KXZ55744.1 - 6e-11 41.6 7.5 4.2e-08 32.6 3.4 3.4 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KXZ55744.1 - 0.0016 16.7 0.1 0.0022 16.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KXZ55744.1 - 0.029 14.1 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 KXZ55744.1 - 0.044 13.5 9.3 0.09 12.5 5.2 3.4 2 2 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 KXZ55744.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase NAD_binding_10 PF13460.6 KXZ55745.1 - 7.8e-08 32.4 0.1 1.1e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXZ55745.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein B9-C2 PF07162.11 KXZ55746.1 - 8e-47 159.6 0.0 9.2e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein AAA_lid_4 PF17864.1 KXZ55747.1 - 0.036 13.8 0.9 0.072 12.9 0.0 1.9 2 0 0 2 2 2 0 RuvB AAA lid domain WD40 PF00400.32 KXZ55747.1 - 0.04 14.8 0.9 7.4 7.6 0.0 3.7 3 1 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.25 KXZ55748.1 - 5.4e-48 163.7 0.0 7.5e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55748.1 - 1.5e-25 90.0 0.0 2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ55748.1 - 7.2e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ55748.1 - 0.00026 19.9 0.0 0.00038 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ55748.1 - 0.0051 16.8 0.2 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXZ55748.1 - 0.032 13.8 0.0 0.072 12.7 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KXZ55748.1 - 0.035 13.7 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 KXZ55748.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FKBP_C PF00254.28 KXZ55749.1 - 0.0012 19.1 0.3 0.017 15.4 0.2 2.2 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_transf_18 PF15024.6 KXZ55750.1 - 6.7e-06 25.0 4.5 7.6e-06 24.8 4.5 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 18 Cpn10 PF00166.21 KXZ55751.1 - 4.1e-18 65.2 0.1 5.2e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PCRF PF03462.18 KXZ55752.1 - 3.2e-68 229.4 1.1 3.2e-68 229.4 1.1 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KXZ55752.1 - 4.7e-37 126.5 2.5 4.7e-37 126.5 2.5 2.2 2 0 0 2 2 2 1 RF-1 domain PhyH PF05721.13 KXZ55753.1 - 8.4e-53 179.8 0.0 1e-52 179.5 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Helicase_C PF00271.31 KXZ55754.1 - 2.7e-05 24.5 0.0 6.1e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DTW PF03942.15 KXZ55755.1 - 1e-14 54.7 0.0 4.2e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 DTW domain Kinesin PF00225.23 KXZ55756.1 - 9.9e-111 369.8 0.7 2.2e-110 368.7 0.7 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ55756.1 - 4.1e-24 85.2 0.1 2.1e-23 82.9 0.1 2.3 1 0 0 1 1 1 1 Microtubule binding ELF PF03317.13 KXZ55756.1 - 0.0046 17.0 0.9 0.031 14.3 0.2 2.4 2 0 0 2 2 2 1 ELF protein Baculo_PEP_C PF04513.12 KXZ55756.1 - 0.21 11.6 19.2 3.9 7.5 0.1 4.6 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KXZ55756.1 - 1 9.2 62.4 0.014 15.3 16.1 3.8 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain HMMR_N PF15905.5 KXZ55756.1 - 4.5 6.7 35.3 1.5 8.2 13.7 2.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ApoLp-III PF07464.11 KXZ55756.1 - 8.7 6.4 35.3 0.96 9.5 6.6 4.5 4 1 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF900 PF05990.12 KXZ55758.1 - 8.3e-18 64.7 0.0 7.7e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) EXS PF03124.14 KXZ55758.1 - 0.11 11.8 1.1 0.18 11.1 1.1 1.3 1 0 0 1 1 1 0 EXS family Trypan_PARP PF05887.11 KXZ55759.1 - 0.023 14.7 1.6 0.031 14.3 1.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Aminotran_1_2 PF00155.21 KXZ55760.1 - 1.8e-56 191.9 0.0 2.2e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KXZ55760.1 - 0.037 12.9 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Allinase Aa_trans PF01490.18 KXZ55761.1 - 2.4e-27 95.7 0.1 7.8e-14 51.2 2.7 3.0 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXZ55761.1 - 0.008 15.3 4.1 0.018 14.1 4.1 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family SymE_toxin PF08845.10 KXZ55761.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system Rotamase PF00639.21 KXZ55762.1 - 5.6e-20 72.1 0.0 8.8e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain FHA PF00498.26 KXZ55762.1 - 2.2e-17 63.2 0.2 2.2e-17 63.2 0.2 1.6 2 0 0 2 2 2 1 FHA domain Rotamase_3 PF13616.6 KXZ55762.1 - 3.5e-16 59.8 0.0 5.4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Yop-YscD_cpl PF16697.5 KXZ55762.1 - 8.1e-07 29.3 0.1 1.8e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Glyco_transf_43 PF03360.16 KXZ55762.1 - 0.055 13.3 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 43 PG_binding_1 PF01471.18 KXZ55762.1 - 0.14 12.4 0.1 0.47 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain X8 PF07983.13 KXZ55762.1 - 0.16 12.7 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 X8 domain Acyltransferase PF01553.21 KXZ55764.1 - 6.5e-07 29.0 0.3 3.8e-05 23.3 0.3 2.4 1 1 0 1 1 1 1 Acyltransferase Prefoldin_2 PF01920.20 KXZ55765.1 - 6.9e-17 61.3 4.2 7.8e-17 61.2 4.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit OspD PF03207.13 KXZ55765.1 - 0.032 13.6 0.2 0.036 13.4 0.2 1.1 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) DUF1690 PF07956.11 KXZ55765.1 - 0.064 13.7 1.3 0.081 13.3 1.3 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Prefoldin PF02996.17 KXZ55765.1 - 0.067 13.1 3.0 0.52 10.2 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit SlyX PF04102.12 KXZ55765.1 - 0.081 13.6 2.2 1.4 9.6 0.1 2.1 2 0 0 2 2 2 0 SlyX DUF3958 PF13125.6 KXZ55765.1 - 0.14 12.4 3.4 1.2 9.4 3.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) MerR-DNA-bind PF09278.11 KXZ55765.1 - 0.21 12.1 2.2 3.6 8.2 0.1 2.1 2 0 0 2 2 2 0 MerR, DNA binding ATP-synt_DE PF00401.20 KXZ55765.1 - 0.65 10.3 4.6 0.29 11.4 1.3 1.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Val_tRNA-synt_C PF10458.9 KXZ55765.1 - 0.67 10.3 6.4 1.5 9.1 0.7 2.5 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm ABC_tran_CTD PF16326.5 KXZ55765.1 - 1.1 9.6 6.2 0.57 10.5 0.3 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Spc24 PF08286.11 KXZ55765.1 - 1.1 9.5 5.4 32 4.8 5.4 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 HSCB_C PF07743.13 KXZ55765.1 - 2.6 8.6 6.9 42 4.7 6.9 2.3 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Rad60-SLD PF11976.8 KXZ55767.1 - 4.7e-22 77.6 0.0 6e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXZ55767.1 - 3.2e-11 42.8 0.0 5.2e-11 42.1 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family WD40 PF00400.32 KXZ55768.1 - 1.3e-27 95.4 13.7 7.4e-06 26.6 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55768.1 - 2.8e-05 24.3 0.0 1.2 9.4 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ55768.1 - 0.0089 15.9 0.0 0.096 12.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 KXZ55768.1 - 0.0092 15.1 0.1 0.11 11.5 0.1 2.0 1 1 1 2 2 2 1 VID27 C-terminal WD40-like domain TFIIA PF03153.13 KXZ55768.1 - 4.8 7.1 6.8 11 5.9 6.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KXZ55771.1 - 0.0014 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pirin_C PF05726.13 KXZ55773.1 - 1.4e-21 76.8 0.0 1.8e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.16 KXZ55773.1 - 1.4e-13 50.8 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Pirin PHO4 PF01384.20 KXZ55775.1 - 3.3e-16 59.3 0.8 4.6e-16 58.8 0.8 1.2 1 0 0 1 1 1 1 Phosphate transporter family ABA_GPCR PF12430.8 KXZ55776.1 - 2.7e-15 56.6 5.7 6.2e-13 48.9 0.5 2.9 2 1 1 3 3 3 2 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KXZ55776.1 - 4e-14 52.4 0.1 7.4e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal RPN1_RPN2_N PF17781.1 KXZ55777.1 - 7.2e-113 377.0 0.0 1e-112 376.6 0.0 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KXZ55777.1 - 1.4e-30 105.1 0.1 2.6e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KXZ55777.1 - 2.6e-24 84.4 21.0 2.8e-08 33.8 0.2 8.6 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXZ55777.1 - 1.5e-06 28.5 4.1 0.22 11.9 0.0 4.7 3 1 1 4 4 4 3 HEAT repeats HALZ PF02183.18 KXZ55777.1 - 0.036 14.3 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase PF00069.25 KXZ55778.1 - 1.1e-56 192.2 0.0 1.4e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55778.1 - 5.5e-28 98.0 0.0 7.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ55778.1 - 8.2e-06 24.8 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXZ55778.1 - 8.3e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ55778.1 - 0.0012 18.8 0.1 0.0036 17.3 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ55778.1 - 0.027 13.8 0.4 0.079 12.3 0.0 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXZ55778.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CCT PF06203.14 KXZ55779.1 - 6.8e-15 54.8 6.7 1.1e-14 54.1 6.7 1.3 1 0 0 1 1 1 1 CCT motif bMG10 PF17973.1 KXZ55780.1 - 4e-13 49.7 0.0 4.1e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M PF00207.22 KXZ55780.1 - 1.3e-05 25.0 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin family EF-hand_7 PF13499.6 KXZ55781.1 - 5.1e-07 30.1 0.0 2.2e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXZ55781.1 - 1.5e-05 24.6 0.0 0.0017 18.1 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 KXZ55781.1 - 0.0024 18.7 0.0 0.006 17.4 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KXZ55781.1 - 0.0037 16.7 0.0 0.035 13.7 0.0 2.6 3 0 0 3 3 3 1 EF hand UNC-50 PF05216.13 KXZ55782.1 - 3.2e-47 160.9 15.8 4e-47 160.6 15.8 1.2 1 0 0 1 1 1 1 UNC-50 family Porin_6 PF16939.5 KXZ55782.1 - 0.072 12.2 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Putative porin p450 PF00067.22 KXZ55784.1 - 1.5e-82 277.8 0.0 2e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Palm_thioest PF02089.15 KXZ55785.1 - 2.9e-72 243.4 0.0 3.4e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KXZ55785.1 - 0.047 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KXZ55785.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 KXZ55785.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) SdiA-regulated PF06977.11 KXZ55786.1 - 1e-26 93.7 0.0 4.4e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 SdiA-regulated Phytase-like PF13449.6 KXZ55786.1 - 5.8e-07 29.7 0.0 0.00043 20.3 0.0 3.3 2 2 0 2 2 2 2 Esterase-like activity of phytase bMG10 PF17973.1 KXZ55787.1 - 6.1e-17 62.0 0.0 1.5e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M PF00207.22 KXZ55787.1 - 6.4e-10 38.7 0.1 3e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Alpha-2-macroglobulin family Big_5 PF13205.6 KXZ55787.1 - 4.4e-05 24.1 0.4 1.4 9.7 0.0 4.4 4 0 0 4 4 4 2 Bacterial Ig-like domain EGF_2 PF07974.13 KXZ55787.1 - 0.00023 21.4 11.6 0.00056 20.2 11.6 1.7 1 0 0 1 1 1 1 EGF-like domain A2M_BRD PF07703.14 KXZ55787.1 - 0.0016 18.8 0.0 0.012 16.0 0.0 2.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain hEGF PF12661.7 KXZ55787.1 - 0.22 12.2 8.3 0.51 11.0 8.3 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 KXZ55787.1 - 0.94 9.8 7.9 2.2 8.7 7.9 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 KXZ55787.1 - 1.6 8.8 8.8 3.5 7.8 8.8 1.6 1 0 0 1 1 1 0 Tenascin EGF domain I-EGF_1 PF18372.1 KXZ55787.1 - 2.5 8.3 7.4 5.2 7.2 7.4 1.5 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Laminin_EGF PF00053.24 KXZ55787.1 - 5.2 7.3 11.0 4.7 7.4 9.2 1.8 1 1 1 2 2 2 0 Laminin EGF domain zf-RING_2 PF13639.6 KXZ55788.1 - 1.1e-13 51.3 4.6 1.6e-13 50.7 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXZ55788.1 - 3.3e-11 42.7 2.7 3.3e-11 42.7 2.7 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KXZ55788.1 - 1.4e-09 38.0 2.5 3.3e-09 36.9 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXZ55788.1 - 1.5e-09 37.5 3.4 2.4e-09 36.9 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ55788.1 - 1.3e-08 34.5 2.8 2e-08 34.0 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KXZ55788.1 - 2.1e-08 34.1 0.0 2.1e-08 34.1 0.0 2.6 3 1 0 3 3 1 1 PA domain zf-RING_UBOX PF13445.6 KXZ55788.1 - 1.4e-06 28.2 1.5 2.6e-06 27.4 1.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ55788.1 - 2.2e-06 27.5 4.1 3.3e-06 26.9 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXZ55788.1 - 0.00018 21.3 3.7 0.00026 20.8 3.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ55788.1 - 0.00072 19.4 3.7 0.0012 18.7 3.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXZ55788.1 - 0.0055 16.7 1.6 0.011 15.7 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 KXZ55788.1 - 0.13 12.4 0.7 0.26 11.4 0.7 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 KXZ55788.1 - 0.41 10.3 4.2 1.1 9.0 4.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KXZ55788.1 - 0.87 9.8 4.3 1.9 8.7 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KXZ55788.1 - 1.1 9.2 6.4 1.3 8.9 4.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXZ55788.1 - 1.5 9.1 4.2 3.8 7.7 4.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KXZ55788.1 - 2.1 8.3 4.0 4.3 7.3 4.0 1.5 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KXZ55788.1 - 2.1 8.5 3.7 4.3 7.6 3.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FAD_binding_4 PF01565.23 KXZ55789.1 - 5.4e-22 78.0 0.2 1e-21 77.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXZ55789.1 - 3.9e-08 33.3 0.2 8e-08 32.3 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Arm PF00514.23 KXZ55790.1 - 0.0011 19.0 0.6 0.26 11.4 0.0 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXZ55790.1 - 0.0063 16.9 11.1 0.0084 16.5 0.4 3.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KXZ55790.1 - 0.11 12.8 0.5 0.11 12.8 0.5 3.5 5 0 0 5 5 5 0 HEAT repeat GST_N_2 PF13409.6 KXZ55791.1 - 4.3e-05 23.7 0.1 8.6e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXZ55791.1 - 0.00019 21.8 0.0 0.00039 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXZ55791.1 - 0.00027 21.1 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXZ55791.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ55791.1 - 0.0022 18.0 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 3Beta_HSD PF01073.19 KXZ55793.1 - 1.2e-35 122.9 0.0 2.3e-30 105.6 0.0 2.9 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXZ55793.1 - 1.2e-21 77.3 0.0 7.5e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXZ55793.1 - 5.4e-09 36.2 0.0 5.4e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXZ55793.1 - 5.6e-09 35.5 1.0 4.6e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXZ55793.1 - 2.8e-08 33.2 0.1 1.9e-05 24.0 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KXZ55793.1 - 6.9e-08 32.3 0.0 5.7e-07 29.2 0.0 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXZ55793.1 - 9.1e-05 21.7 0.1 0.00097 18.3 0.1 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXZ55793.1 - 0.00038 20.0 1.3 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXZ55793.1 - 0.037 13.9 4.1 0.44 10.4 4.1 2.3 1 1 0 1 1 1 0 KR domain WD40 PF00400.32 KXZ55794.1 - 3.5e-60 198.5 6.8 6.9e-11 42.5 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat IspD PF01128.19 KXZ55794.1 - 1.9e-56 191.3 0.0 3.1e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ANAPC4_WD40 PF12894.7 KXZ55794.1 - 1.1e-12 48.0 0.0 0.07 13.4 0.0 5.8 2 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NTP_transf_3 PF12804.7 KXZ55794.1 - 3.9e-10 40.3 2.9 4.6e-10 40.1 0.3 2.6 2 1 0 2 2 2 1 MobA-like NTP transferase domain Ge1_WD40 PF16529.5 KXZ55794.1 - 1.7e-07 30.5 0.0 0.029 13.3 0.0 4.6 3 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXZ55794.1 - 0.0001 21.1 0.3 0.0066 15.1 0.0 2.8 3 1 0 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 KXZ55794.1 - 0.032 14.2 0.0 36 4.5 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat UDPGP PF01704.18 KXZ55794.1 - 0.18 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase Fasciclin PF02469.22 KXZ55795.1 - 9.3e-18 64.7 0.6 1.1e-17 64.4 0.6 1.1 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 KXZ55796.1 - 1.4e-16 60.8 0.0 1.8e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain NdhS PF11623.8 KXZ55796.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S Fasciclin PF02469.22 KXZ55797.1 - 3.4e-11 43.4 0.0 4.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain PKcGMP_CC PF16808.5 KXZ55798.1 - 0.028 14.3 0.1 0.028 14.3 0.1 3.7 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Streptin-Immun PF11083.8 KXZ55798.1 - 0.053 13.9 2.1 2.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Lectin_N PF03954.14 KXZ55798.1 - 0.07 12.9 5.7 3.5 7.4 0.4 3.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain SKA1 PF07160.12 KXZ55798.1 - 0.37 10.6 13.3 1 9.1 4.4 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Fib_alpha PF08702.10 KXZ55798.1 - 1.2 9.4 9.4 13 6.0 2.4 3.2 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family FH2 PF02181.23 KXZ55798.1 - 1.4 7.9 8.6 0.2 10.7 1.8 2.5 2 1 0 2 2 2 0 Formin Homology 2 Domain Prefoldin_2 PF01920.20 KXZ55798.1 - 3.8 7.5 19.6 8.6 6.4 3.1 4.7 4 0 0 4 4 4 0 Prefoldin subunit betaPIX_CC PF16523.5 KXZ55798.1 - 5 7.0 9.5 3.2 7.6 0.9 2.9 3 0 0 3 3 3 0 betaPIX coiled coil V_ATPase_I PF01496.19 KXZ55798.1 - 5.8 4.7 13.0 0.38 8.6 5.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PKcGMP_CC PF16808.5 KXZ55799.1 - 0.26 11.2 0.1 0.26 11.2 0.1 4.9 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TSC22 PF01166.18 KXZ55799.1 - 0.68 10.3 6.9 1.8 9.0 0.6 4.6 5 1 1 6 6 6 0 TSC-22/dip/bun family Tropomyosin PF00261.20 KXZ55799.1 - 1.1 8.6 68.0 0.28 10.5 12.8 4.2 3 2 0 4 4 4 0 Tropomyosin TMCO5 PF14992.6 KXZ55799.1 - 1.1 8.8 25.2 0.02 14.5 6.3 4.1 2 1 1 4 4 4 0 TMCO5 family DUF4618 PF15397.6 KXZ55799.1 - 6.4 6.1 36.9 0.088 12.2 0.6 5.2 3 2 2 6 6 6 0 Domain of unknown function (DUF4618) SHE3 PF17078.5 KXZ55799.1 - 8.5 6.0 16.2 0.37 10.5 4.2 3.0 2 2 0 2 2 2 0 SWI5-dependent HO expression protein 3 Glyco_transf_49 PF13896.6 KXZ55800.1 - 1.2e-07 31.4 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Pkinase_Tyr PF07714.17 KXZ55801.1 - 2.7e-52 177.6 0.0 3.6e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ55801.1 - 1.4e-50 172.1 0.0 1.8e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXZ55801.1 - 1.7e-05 24.3 0.0 3e-05 23.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXZ55801.1 - 0.008 16.1 0.2 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ55801.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXZ55801.1 - 0.018 14.0 0.0 0.54 9.2 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXZ55801.1 - 0.068 11.9 0.0 0.12 11.1 0.0 1.3 2 0 0 2 2 2 0 Fungal protein kinase Guanylate_cyc PF00211.20 KXZ55802.1 - 3.5e-44 150.6 0.0 1.3e-43 148.8 0.0 1.9 2 1 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Rubis-subs-bind PF09273.11 KXZ55802.1 - 3.6e-05 24.4 0.2 0.00028 21.6 0.2 2.2 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 KXZ55802.1 - 0.0024 18.3 0.0 0.0053 17.2 0.0 1.6 1 0 0 1 1 1 1 SET domain LRR_4 PF12799.7 KXZ55803.1 - 0.89 10.1 2.5 32 5.1 0.0 3.8 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) TPM_phosphatase PF04536.14 KXZ55804.1 - 3.3e-09 37.0 0.0 5.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 TPM domain zf-C3HC4_2 PF13923.6 KXZ55804.1 - 8.6e-07 28.7 1.4 8.6e-07 28.7 1.4 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ55804.1 - 5.9e-06 26.0 0.2 5.9e-06 26.0 0.2 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXZ55804.1 - 9.7e-06 25.4 0.8 9.7e-06 25.4 0.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXZ55804.1 - 6.4e-05 22.7 4.3 0.00011 22.0 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXZ55804.1 - 0.00013 22.2 0.6 0.00013 22.2 0.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 KXZ55804.1 - 0.00088 19.1 2.1 0.00088 19.1 2.1 3.2 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KXZ55804.1 - 0.0053 17.0 0.2 0.014 15.7 0.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXZ55804.1 - 0.0055 16.7 6.3 0.02 14.9 5.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXZ55804.1 - 0.0081 16.0 0.9 0.0081 16.0 0.9 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 MOLO1 PF17175.4 KXZ55804.1 - 0.021 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 zf-RING_11 PF17123.5 KXZ55804.1 - 0.13 12.0 1.7 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KXZ55804.1 - 8.8 6.6 9.5 0.84 9.8 3.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Adap_comp_sub PF00928.21 KXZ55805.1 - 1.1e-74 251.1 0.0 1.4e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXZ55805.1 - 0.0011 18.9 0.1 0.0022 18.0 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KXZ55805.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Ank_2 PF12796.7 KXZ55806.1 - 6.9e-68 225.3 20.3 5.2e-15 55.8 0.8 6.5 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ55806.1 - 5.1e-47 157.7 15.1 6.6e-08 32.9 0.1 9.4 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ55806.1 - 8.1e-43 143.9 23.2 1.2e-09 38.3 0.3 9.0 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KXZ55806.1 - 6.7e-42 140.2 36.6 9.1e-05 22.7 0.0 13.2 14 0 0 14 14 14 9 Ankyrin repeat Ank_3 PF13606.6 KXZ55806.1 - 7.4e-41 133.5 16.1 0.00018 21.7 0.0 12.5 12 0 0 12 12 12 8 Ankyrin repeat Pkinase PF00069.25 KXZ55808.1 - 6.9e-47 160.0 0.0 9.1e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55808.1 - 1.6e-26 93.2 0.0 2.1e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ55808.1 - 0.0017 18.3 0.1 0.0017 18.3 0.1 2.9 2 2 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXZ55808.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KXZ55808.1 - 0.018 14.4 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ55808.1 - 0.088 12.1 0.0 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like 3-alpha PF03475.14 KXZ55808.1 - 0.18 11.7 0.8 0.48 10.3 0.3 2.0 2 0 0 2 2 2 0 3-alpha domain Serglycin PF04360.12 KXZ55808.1 - 2.8 7.9 3.7 4.9 7.1 3.7 1.3 1 0 0 1 1 1 0 Serglycin Pkinase PF00069.25 KXZ55809.1 - 7.2e-53 179.6 0.0 9.2e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55809.1 - 2.2e-26 92.7 0.0 2.9e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ55809.1 - 0.0012 18.8 0.1 0.0041 17.1 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXZ55809.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KXZ55809.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXZ55809.1 - 0.071 12.4 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like SDA1 PF05285.12 KXZ55810.1 - 8.2 5.7 10.4 13 5.1 10.4 1.2 1 0 0 1 1 1 0 SDA1 SET PF00856.28 KXZ55811.1 - 0.02 15.2 0.0 0.33 11.3 0.0 2.4 1 1 0 1 1 1 0 SET domain DUF563 PF04577.14 KXZ55812.1 - 1.2e-10 42.0 0.0 2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Sulfotransfer_2 PF03567.14 KXZ55813.1 - 0.00035 20.6 0.2 0.001 19.0 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family Cmc1 PF08583.10 KXZ55815.1 - 1.5e-10 41.0 1.0 2.2e-10 40.4 0.9 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like RyR PF02026.16 KXZ55815.1 - 0.05 13.8 1.0 0.076 13.2 1.0 1.2 1 0 0 1 1 1 0 RyR domain DDE_Tnp_1_assoc PF13808.6 KXZ55816.1 - 0.054 13.5 0.9 0.73 9.9 0.1 2.7 3 0 0 3 3 3 0 DDE_Tnp_1-associated FRQ PF09421.10 KXZ55816.1 - 1.2 7.1 8.7 1.8 6.5 8.7 1.2 1 0 0 1 1 1 0 Frequency clock protein Mito_carr PF00153.27 KXZ55817.1 - 1.3e-35 121.2 0.4 9.5e-20 70.3 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Orn_Arg_deC_N PF02784.16 KXZ55818.1 - 1.2e-74 250.8 0.0 1.7e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXZ55818.1 - 2.3e-14 53.4 0.0 3.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KXZ55818.1 - 0.099 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Ala_racemase_N PF01168.20 KXZ55818.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Tfb5 PF06331.12 KXZ55819.1 - 9.1e-11 41.6 0.2 5.4e-09 35.9 0.0 2.0 1 1 1 2 2 2 2 Transcription factor TFIIH complex subunit Tfb5 Acid_phosphat_B PF03767.14 KXZ55819.1 - 0.1 12.2 0.0 0.1 12.2 0.0 1.0 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hexokinase_1 PF00349.21 KXZ55819.1 - 0.17 11.8 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Hexokinase Na_Ca_ex PF01699.24 KXZ55820.1 - 2.2e-29 102.3 21.9 8.5e-15 55.0 6.4 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein LigB PF02900.18 KXZ55822.1 - 4e-08 32.7 0.0 4.3e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Herpes_TAF50 PF03326.13 KXZ55822.1 - 0.18 10.4 2.0 0.25 9.9 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) FAM199X PF15814.5 KXZ55822.1 - 1 8.4 5.6 1.5 7.8 5.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X Pkinase PF00069.25 KXZ55823.1 - 5.1e-42 144.1 0.0 1.2e-41 142.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55823.1 - 1.2e-20 74.0 0.0 7.7e-19 68.0 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ55823.1 - 0.00064 19.1 0.0 0.018 14.4 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ55823.1 - 0.0011 18.9 0.1 0.0011 18.9 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ55823.1 - 0.05 13.0 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ55823.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MnmE_helical PF12631.7 KXZ55825.1 - 1.1e-45 156.4 0.0 1.4e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KXZ55825.1 - 5.3e-38 129.9 0.0 1.4e-37 128.5 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KXZ55825.1 - 1.1e-23 83.5 0.0 1.9e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ55825.1 - 1.8e-09 37.3 0.1 9.1e-09 35.0 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXZ55825.1 - 0.0096 16.0 0.0 0.11 12.6 0.0 2.0 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 KXZ55825.1 - 0.016 15.6 1.0 0.16 12.4 1.0 2.6 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 KXZ55825.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 KXZ55825.1 - 0.04 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AIG1 PF04548.16 KXZ55825.1 - 0.054 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 AIG1 family MCM PF00493.23 KXZ55825.1 - 0.089 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Roc PF08477.13 KXZ55825.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase zf-C3HC4_3 PF13920.6 KXZ55826.1 - 3e-10 39.8 7.4 4.9e-10 39.1 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 KXZ55826.1 - 0.18 11.6 0.3 0.34 10.7 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_2 PF13639.6 KXZ55826.1 - 0.28 11.6 8.5 0.46 10.9 8.5 1.4 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KXZ55826.1 - 0.42 10.5 6.5 0.86 9.5 6.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.14 KXZ55826.1 - 1 9.0 3.6 1.9 8.2 3.6 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_5 PF14634.6 KXZ55826.1 - 5.9 6.9 8.1 9 6.4 8.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain ANAPC8 PF04049.13 KXZ55829.1 - 6.3e-14 52.2 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_19 PF14559.6 KXZ55829.1 - 6.6e-07 29.7 7.7 0.015 15.8 2.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ55829.1 - 0.00012 22.6 18.0 0.0024 18.5 1.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ55829.1 - 0.00028 21.5 13.1 0.12 13.3 0.5 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ55829.1 - 0.00039 20.6 4.9 0.02 15.1 0.1 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KXZ55829.1 - 0.00087 19.2 8.4 1.6 9.0 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ55829.1 - 0.055 14.1 9.9 6.6 7.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ55829.1 - 0.12 12.6 0.8 78 3.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ55829.1 - 0.32 11.1 1.8 16 5.7 0.0 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DEC-1_N PF04625.13 KXZ55829.1 - 1.5 7.8 3.2 2.3 7.2 3.2 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TPR_20 PF14561.6 KXZ55829.1 - 2.1 8.8 4.5 13 6.2 0.0 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ55829.1 - 3.6 7.9 12.0 3.4 8.0 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ55829.1 - 6.1 7.8 19.9 0.69 10.7 2.6 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat Exostosin PF03016.15 KXZ55831.1 - 2.7e-26 92.5 0.0 4.1e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 KXZ55831.1 - 0.022 15.1 31.6 0.055 13.8 14.4 2.8 2 0 0 2 2 2 0 EGF-like domain Exostosin PF03016.15 KXZ55832.1 - 3.4e-20 72.5 0.1 1.6e-18 66.9 0.0 2.1 1 1 1 2 2 2 2 Exostosin family EGF_2 PF07974.13 KXZ55832.1 - 0.0026 18.1 14.1 0.0079 16.5 14.1 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 KXZ55832.1 - 0.068 13.2 9.1 0.16 12.1 9.1 1.6 1 0 0 1 1 1 0 Tenascin EGF domain F-box PF00646.33 KXZ55833.1 - 0.0043 16.9 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain Solute_trans_a PF03619.16 KXZ55834.1 - 6.2e-71 239.0 13.4 8.7e-71 238.5 13.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DEAD PF00270.29 KXZ55835.1 - 5e-17 62.2 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ55835.1 - 1.2e-13 51.4 0.0 6.6e-13 49.0 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HRDC PF00570.23 KXZ55835.1 - 1.9e-05 24.6 1.6 2.5e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 HRDC domain RQC PF09382.10 KXZ55835.1 - 0.00062 19.5 0.2 0.0029 17.4 0.2 2.0 1 1 0 1 1 1 1 RQC domain UPF0184 PF03670.13 KXZ55835.1 - 0.024 15.0 0.6 0.067 13.6 0.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) EMP24_GP25L PF01105.24 KXZ55835.1 - 0.025 14.5 0.2 0.053 13.5 0.2 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD RecQ_Zn_bind PF16124.5 KXZ55835.1 - 0.052 14.3 8.3 0.21 12.4 8.3 2.1 1 0 0 1 1 1 0 RecQ zinc-binding THOC7 PF05615.13 KXZ55835.1 - 1.2 9.4 6.0 2.3 8.5 6.0 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 PRKG1_interact PF15898.5 KXZ55835.1 - 1.9 9.5 5.6 0.88 10.5 1.6 2.3 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain MFS_1 PF07690.16 KXZ55838.1 - 5.6e-41 140.6 30.1 2.9e-30 105.4 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YlmH_RBD PF17774.1 KXZ55839.1 - 7e-13 48.7 0.0 2.7e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 Putative RNA-binding domain in YlmH S4 PF01479.25 KXZ55839.1 - 1.6e-08 34.1 0.0 3.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain DUF1062 PF06353.12 KXZ55839.1 - 0.075 13.9 0.0 0.19 12.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1062) BING4CT PF08149.11 KXZ55840.1 - 1.9e-34 117.3 0.0 7.7e-33 112.1 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain LRR_8 PF13855.6 KXZ55840.1 - 2.2e-26 91.4 17.2 7.3e-05 22.5 0.2 7.8 5 3 0 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KXZ55840.1 - 2.2e-12 46.9 15.2 0.039 14.4 0.3 7.4 4 3 4 8 8 8 6 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 KXZ55840.1 - 1.7e-08 34.6 0.2 1.7e-08 34.6 0.2 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain WD40 PF00400.32 KXZ55840.1 - 1.4e-07 32.1 0.1 4.7e-05 24.1 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXZ55840.1 - 0.0038 16.3 0.0 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 KXZ55840.1 - 0.0071 16.6 0.0 23 5.4 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain LRR_1 PF00560.33 KXZ55840.1 - 0.46 11.2 18.2 99 4.1 0.0 8.8 10 2 1 11 11 11 0 Leucine Rich Repeat Prefoldin_2 PF01920.20 KXZ55841.1 - 7.5e-17 61.2 8.4 9.2e-17 60.9 8.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit ABC_tran_CTD PF16326.5 KXZ55841.1 - 0.0008 19.6 1.4 0.0008 19.6 1.4 1.9 2 0 0 2 2 2 1 ABC transporter C-terminal domain Syntaxin-6_N PF09177.11 KXZ55841.1 - 0.0083 16.7 2.6 0.038 14.5 2.6 2.1 1 1 0 1 1 1 1 Syntaxin 6, N-terminal COG5 PF10392.9 KXZ55841.1 - 0.011 15.9 0.5 0.018 15.2 0.5 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Med4 PF10018.9 KXZ55841.1 - 0.014 15.1 1.5 0.014 15.1 1.5 1.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Cluap1 PF10234.9 KXZ55841.1 - 0.019 14.4 2.9 0.02 14.3 2.9 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 zf-C4H2 PF10146.9 KXZ55841.1 - 0.034 14.5 1.5 0.038 14.3 1.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Vps5 PF09325.10 KXZ55841.1 - 0.039 13.5 3.5 0.043 13.3 3.5 1.0 1 0 0 1 1 1 0 Vps5 C terminal like Lectin_N PF03954.14 KXZ55841.1 - 0.048 13.4 0.4 0.085 12.6 0.4 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Tsc35 PF15079.6 KXZ55841.1 - 0.084 12.4 4.0 0.11 12.0 4.0 1.2 1 0 0 1 1 1 0 Testis-specific protein 35 ATP-grasp_6 PF18419.1 KXZ55841.1 - 0.13 11.9 1.8 0.28 10.8 0.1 2.3 2 1 1 3 3 3 0 ATP-grasp-like domain DUF1664 PF07889.12 KXZ55841.1 - 0.16 12.0 5.0 0.47 10.5 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_23 PF13476.6 KXZ55841.1 - 0.28 11.7 3.3 0.32 11.5 3.3 1.1 1 0 0 1 1 1 0 AAA domain Val_tRNA-synt_C PF10458.9 KXZ55841.1 - 0.28 11.5 4.8 7.9 6.9 0.2 2.7 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm COG2 PF06148.11 KXZ55841.1 - 0.35 11.0 3.5 0.59 10.2 3.5 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 KXZ55841.1 - 0.38 10.9 4.6 0.49 10.6 4.6 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.10 KXZ55841.1 - 0.39 11.0 3.9 12 6.2 3.9 2.2 1 1 0 1 1 1 0 Osmosensory transporter coiled coil DMPK_coil PF08826.10 KXZ55841.1 - 0.71 10.0 7.8 0.2 11.8 4.3 1.8 2 0 0 2 2 2 0 DMPK coiled coil domain like KxDL PF10241.9 KXZ55841.1 - 1.4 9.3 6.4 0.37 11.1 3.4 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein FAM184 PF15665.5 KXZ55842.1 - 1.1e-06 28.6 23.6 1.1e-06 28.6 23.6 8.3 1 1 8 9 9 9 2 Family with sequence similarity 184, A and B Trans_reg_C PF00486.28 KXZ55842.1 - 0.017 15.2 4.9 6.4 6.9 0.1 4.8 4 1 1 5 5 5 0 Transcriptional regulatory protein, C terminal DUF2935 PF11155.8 KXZ55842.1 - 0.11 12.8 8.2 40 4.6 0.0 6.2 2 2 2 4 4 4 0 Domain of unknown function (DUF2935) Syntaxin_2 PF14523.6 KXZ55842.1 - 2.3 8.6 33.0 0.44 11.0 0.9 5.9 5 1 1 6 6 6 0 Syntaxin-like protein SAP PF02037.27 KXZ55842.1 - 3.4 7.5 11.2 0.078 12.8 0.7 3.9 4 0 0 4 4 4 0 SAP domain PLATZ PF04640.14 KXZ55843.1 - 5.3e-22 78.2 0.0 9.7e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 PLATZ transcription factor Paired_CXXCH_1 PF09699.10 KXZ55843.1 - 3.6 7.4 7.0 3.9 7.3 1.5 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) PAP_fibrillin PF04755.12 KXZ55844.1 - 3.2e-08 33.8 0.0 0.00041 20.4 0.1 2.4 1 1 1 2 2 2 2 PAP_fibrillin Oleosin PF01277.17 KXZ55844.1 - 0.022 14.5 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 Oleosin Phage_holin_3_6 PF07332.11 KXZ55844.1 - 0.035 14.2 3.0 0.057 13.5 3.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AF-4 PF05110.13 KXZ55845.1 - 1.1 7.2 15.3 1.4 6.9 15.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ada3 PF10198.9 KXZ55845.1 - 10 6.3 18.1 0.018 15.2 3.2 2.2 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 zf-MYND PF01753.18 KXZ55848.1 - 1.3e-08 34.8 10.3 2.6e-08 33.8 10.3 1.5 1 0 0 1 1 1 1 MYND finger BACK PF07707.15 KXZ55851.1 - 1.6e-08 34.6 0.1 3.3e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ55851.1 - 0.0044 17.2 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KXZ55852.1 - 8.1e-09 35.5 0.1 1.5e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch T6SS_VasJ PF16989.5 KXZ55852.1 - 0.022 14.3 0.2 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ BACK PF07707.15 KXZ55853.1 - 4.2e-09 36.4 0.2 8.8e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KXZ55853.1 - 4.8e-06 26.8 0.0 0.00012 22.3 0.0 2.6 1 1 0 1 1 1 1 BTB/POZ domain AAA_25 PF13481.6 KXZ55854.1 - 5.2e-05 22.9 0.3 0.001 18.7 0.3 2.6 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KXZ55854.1 - 0.00023 20.6 0.0 0.0048 16.3 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AIRC PF00731.20 KXZ55857.1 - 4.6e-65 217.7 2.3 1.2e-64 216.4 2.3 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KXZ55857.1 - 2.6e-59 199.6 0.0 4.4e-59 198.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KXZ55857.1 - 1.8e-18 66.0 0.3 3.4e-18 65.1 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KXZ55857.1 - 7.9e-05 22.3 0.0 0.00024 20.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus NAD_binding_2 PF03446.15 KXZ55857.1 - 0.0011 19.1 0.1 0.0043 17.2 0.1 2.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXZ55857.1 - 0.0013 18.7 0.4 0.0084 16.0 0.3 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.14 KXZ55857.1 - 0.0048 17.0 0.0 0.036 14.1 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.19 KXZ55857.1 - 0.031 13.6 0.0 0.084 12.2 0.0 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAP_fibrillin PF04755.12 KXZ55858.1 - 9.7e-11 42.0 0.1 2e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 PAP_fibrillin CRAL_TRIO PF00650.20 KXZ55859.1 - 6.6e-27 94.2 0.0 1e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KXZ55859.1 - 0.00039 20.6 0.0 0.00057 20.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Exo_endo_phos PF03372.23 KXZ55860.1 - 1.3e-19 70.6 0.7 4e-19 69.1 0.7 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TRAM_LAG1_CLN8 PF03798.16 KXZ55861.1 - 2.1e-24 86.4 11.0 2.7e-24 86.0 11.0 1.1 1 0 0 1 1 1 1 TLC domain DUF4880 PF16220.5 KXZ55861.1 - 3.3 7.7 7.3 0.32 10.9 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Methyltransf_11 PF08241.12 KXZ55862.1 - 5.7e-14 52.5 0.1 2.4e-12 47.3 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ55862.1 - 8.7e-14 51.6 0.0 1.1e-05 25.3 0.1 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ55862.1 - 2e-13 50.9 0.1 4.5e-11 43.3 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ55862.1 - 8.6e-13 48.9 0.0 2.8e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ55862.1 - 2.3e-11 43.8 0.0 3.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ55862.1 - 0.0014 18.0 0.0 0.004 16.5 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXZ55862.1 - 0.015 14.7 0.0 0.03 13.8 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 KXZ55862.1 - 0.023 14.0 0.3 2.1 7.6 0.1 2.1 1 1 1 2 2 2 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KXZ55862.1 - 0.065 13.2 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.6 KXZ55866.1 - 7.6e-24 83.2 2.2 3.9e-08 32.9 0.2 3.6 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KXZ55866.1 - 5.1e-21 74.4 6.8 3.6e-06 27.2 0.4 4.8 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXZ55866.1 - 8.3e-09 34.8 0.7 16 6.5 0.0 7.3 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 KXZ55866.1 - 5.1e-07 29.4 0.0 0.0043 16.6 0.0 2.8 2 1 1 3 3 3 2 Leucine-rich repeat YgbB PF02542.16 KXZ55867.1 - 1.6e-47 161.6 0.0 1.9e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 YgbB family Cys_rich_FGFR PF00839.17 KXZ55868.1 - 1.1e-100 329.7 75.0 5.3e-13 48.9 3.7 12.2 12 0 0 12 12 12 12 Cysteine rich repeat DUF3849 PF12960.7 KXZ55868.1 - 8 6.5 10.5 12 5.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3849) SET PF00856.28 KXZ55869.1 - 6.7e-12 46.1 0.0 4.7e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 SET domain PRP38 PF03371.15 KXZ55870.1 - 2.9e-30 105.4 0.4 3.8e-30 105.0 0.4 1.2 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KXZ55870.1 - 2e-05 25.1 35.4 2e-05 25.1 35.4 5.3 1 1 3 4 4 4 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Bap31_Bap29_C PF18035.1 KXZ55872.1 - 6.4e-07 29.3 8.7 0.003 17.5 5.0 3.6 1 1 1 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 KXZ55872.1 - 0.00014 22.0 2.5 0.1 12.8 0.3 2.8 3 0 0 3 3 3 2 Homeobox associated leucine zipper JIP_LZII PF16471.5 KXZ55872.1 - 0.0018 18.4 0.8 1.1 9.5 0.1 2.3 2 1 1 3 3 3 1 JNK-interacting protein leucine zipper II ZapB PF06005.12 KXZ55872.1 - 0.0026 18.1 3.2 0.14 12.6 0.1 2.7 2 1 1 3 3 3 1 Cell division protein ZapB CENP-F_leu_zip PF10473.9 KXZ55872.1 - 0.0051 16.8 3.0 0.0055 16.7 2.2 1.4 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 KXZ55872.1 - 0.017 15.5 3.7 0.084 13.2 0.6 2.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KASH_CCD PF14662.6 KXZ55872.1 - 0.018 14.8 1.2 1.8 8.4 0.2 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH NRBF2 PF08961.10 KXZ55872.1 - 0.038 13.6 1.7 1.5 8.4 0.2 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Hemerythrin PF01814.23 KXZ55872.1 - 0.042 14.5 1.6 0.049 14.3 1.6 1.1 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain APG6_N PF17675.1 KXZ55872.1 - 0.045 14.3 4.7 0.066 13.7 4.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Filament PF00038.21 KXZ55872.1 - 0.049 13.2 2.7 0.059 13.0 2.7 1.2 1 0 0 1 1 1 0 Intermediate filament protein ADIP PF11559.8 KXZ55872.1 - 0.068 13.3 3.8 0.064 13.3 2.5 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KXZ55872.1 - 0.07 13.2 5.2 0.092 12.8 4.9 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 KXZ55872.1 - 0.086 12.6 8.4 2.3 8.0 0.2 2.8 2 1 1 3 3 3 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 KXZ55872.1 - 0.091 13.0 3.0 0.086 13.1 1.8 1.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Shugoshin_N PF07558.11 KXZ55872.1 - 0.11 12.4 0.0 4.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 KXZ55872.1 - 0.11 13.1 0.8 2.3 8.9 0.0 2.7 1 1 2 3 3 3 0 SlyX GIT_CC PF16559.5 KXZ55872.1 - 0.12 12.2 0.3 22 5.0 0.1 3.2 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Rho_Binding PF08912.11 KXZ55872.1 - 0.14 13.0 2.7 0.16 12.8 1.2 1.8 2 0 0 2 2 2 0 Rho Binding YabA PF06156.13 KXZ55872.1 - 0.17 12.5 0.5 2.2 9.0 0.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF2935 PF11155.8 KXZ55872.1 - 0.28 11.5 0.9 1.4 9.3 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) BRE1 PF08647.11 KXZ55872.1 - 0.29 11.2 5.2 1.1 9.4 5.2 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase FAM76 PF16046.5 KXZ55872.1 - 0.31 10.4 1.2 0.38 10.1 1.2 1.1 1 0 0 1 1 1 0 FAM76 protein PRKG1_interact PF15898.5 KXZ55872.1 - 0.31 12.0 2.5 1.3 10.0 2.5 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain FadA PF09403.10 KXZ55872.1 - 0.43 11.1 4.7 0.72 10.4 4.7 1.5 1 1 0 1 1 1 0 Adhesion protein FadA DUF3450 PF11932.8 KXZ55872.1 - 0.58 9.4 5.4 0.41 9.9 4.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 KXZ55872.1 - 0.66 10.4 8.0 3 8.3 3.3 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-Q PF13094.6 KXZ55872.1 - 1.4 9.1 8.1 4.8 7.4 0.1 2.9 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.19 KXZ55872.1 - 1.5 8.6 8.8 1.8 8.3 8.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.22 KXZ55872.1 - 3.6 7.8 7.9 4.1 7.7 2.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KXZ55872.1 - 4.1 6.7 9.3 12 5.1 9.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SET PF00856.28 KXZ55873.1 - 5.7e-06 26.8 0.1 8.7e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 SET domain SET PF00856.28 KXZ55874.1 - 0.00012 22.5 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 SET domain Arf PF00025.21 KXZ55875.1 - 4.8e-05 22.9 0.1 7.4e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Rubis-subs-bind PF09273.11 KXZ55876.1 - 6.7e-29 101.2 0.0 1.1e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KXZ55876.1 - 1.1e-13 52.0 0.0 2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 SET domain DAO PF01266.24 KXZ55878.1 - 1.1e-05 25.2 0.1 5.2e-05 23.0 0.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXZ55878.1 - 1.3e-05 25.3 1.9 4.6e-05 23.6 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXZ55878.1 - 0.00064 19.1 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KXZ55878.1 - 0.037 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXZ55878.1 - 0.038 13.3 0.2 0.063 12.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXZ55878.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KXZ55878.1 - 0.45 9.7 0.0 0.45 9.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SseC PF04888.12 KXZ55879.1 - 0.32 10.6 8.8 0.36 10.4 8.8 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ABC2_membrane PF01061.24 KXZ55881.1 - 1.1e-25 90.3 21.4 1.1e-25 90.3 21.4 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ55881.1 - 2.1e-19 70.4 0.0 4.4e-19 69.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KXZ55881.1 - 0.0012 18.7 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 KXZ55881.1 - 0.015 15.2 0.5 0.059 13.3 0.5 2.0 1 0 0 1 1 1 0 CDR ABC transporter PDR_assoc PF08370.11 KXZ55881.1 - 0.019 14.7 1.1 0.059 13.1 1.1 1.9 1 0 0 1 1 1 0 Plant PDR ABC transporter associated RsgA_GTPase PF03193.16 KXZ55881.1 - 0.082 12.8 0.3 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXZ55881.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KXZ55881.1 - 0.25 10.4 22.5 0.4 9.7 22.1 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein CPP1-like PF11833.8 KXZ55881.1 - 4.9 6.8 6.5 9.7 5.8 6.5 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NifU PF01106.17 KXZ55882.1 - 6.1e-28 96.8 0.2 8.9e-28 96.2 0.2 1.2 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 KXZ55882.1 - 1.1e-22 79.9 0.0 4.6e-22 77.9 0.0 2.2 2 1 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal Ribosom_S12_S23 PF00164.25 KXZ55883.1 - 1.3e-50 169.8 0.2 1.6e-50 169.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ubiquitin PF00240.23 KXZ55884.1 - 3.4e-05 23.5 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Hydrolase_4 PF12146.8 KXZ55885.1 - 1.5e-50 171.7 0.0 5.8e-50 169.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXZ55885.1 - 5.8e-11 42.3 0.6 3.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXZ55885.1 - 4.9e-07 29.6 1.1 2.8e-06 27.2 1.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXZ55885.1 - 8.4e-07 29.8 0.1 1.2e-06 29.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KXZ55885.1 - 1.6e-06 27.9 0.2 6.5e-06 26.0 0.1 1.8 1 1 1 2 2 2 1 Putative esterase Peptidase_S15 PF02129.18 KXZ55885.1 - 0.00044 19.9 0.0 0.0042 16.7 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KXZ55885.1 - 0.084 12.7 0.1 0.084 12.7 0.1 2.2 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF839 PF05787.13 KXZ55887.1 - 1.4e-44 153.1 4.8 7.5e-26 91.4 0.4 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF839) DUF1727 PF08353.10 KXZ55887.1 - 0.039 13.9 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) CC PF04942.14 KXZ55887.1 - 0.1 12.8 9.8 1 9.6 0.0 2.9 3 0 0 3 3 3 0 CC domain U-box PF04564.15 KXZ55890.1 - 3.6e-12 46.3 0.0 6.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 KXZ55890.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein EF-hand_7 PF13499.6 KXZ55892.1 - 0.011 16.2 0.2 0.018 15.5 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain pair Cullin_binding PF03556.15 KXZ55892.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 Cullin binding CDPS PF16715.5 KXZ55892.1 - 0.17 11.5 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase Glyco_hydro_32N PF00251.20 KXZ55893.1 - 1.9e-58 198.4 1.9 1.7e-44 152.7 0.3 4.1 4 0 0 4 4 4 4 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXZ55893.1 - 9.4e-08 32.2 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal YniB PF14002.6 KXZ55894.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 YniB-like protein LNS2 PF08235.13 KXZ55895.1 - 6.5e-77 258.0 0.0 9.6e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) RIC1 PF07064.13 KXZ55895.1 - 3.2e-45 154.5 0.0 4.7e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KXZ55895.1 - 5.7e-06 26.5 0.0 0.023 15.0 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Lipin_N PF04571.14 KXZ55895.1 - 1.5e-05 24.9 0.1 0.00063 19.7 0.0 2.3 1 1 1 2 2 2 1 lipin, N-terminal conserved region DUF4730 PF15873.5 KXZ55897.1 - 0.9 9.9 0.1 0.9 9.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4730) EF-hand_7 PF13499.6 KXZ55898.1 - 3.3e-13 49.9 0.0 5e-08 33.3 0.0 2.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KXZ55898.1 - 7.3e-11 41.1 0.0 2.1e-06 27.2 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KXZ55898.1 - 1.8e-08 33.3 0.0 5.9e-06 25.5 0.0 3.1 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 KXZ55898.1 - 1e-07 31.1 0.4 2.4e-06 26.8 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KXZ55898.1 - 0.00067 19.4 0.0 0.28 11.1 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KXZ55898.1 - 0.032 14.6 0.0 3.7 7.9 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Uricase PF01014.18 KXZ55900.1 - 1.1e-51 174.4 0.2 6.6e-29 100.8 1.5 2.1 2 0 0 2 2 2 2 Uricase Serine_protease PF18405.1 KXZ55900.1 - 0.034 13.3 0.7 1.6 7.8 0.0 2.1 1 1 1 2 2 2 0 Gammaproteobacterial serine protease F-box PF00646.33 KXZ55901.1 - 0.0035 17.2 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXZ55901.1 - 0.088 12.7 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXZ55902.1 - 0.0021 17.9 0.1 0.0083 16.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXZ55902.1 - 0.007 16.2 0.9 0.019 14.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like Adeno_PIX PF03955.14 KXZ55902.1 - 1.3 9.2 12.7 3.4 7.9 0.2 3.8 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) UvdE PF03851.14 KXZ55903.1 - 4.2e-38 131.2 0.0 5.8e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE UvdE PF03851.14 KXZ55904.1 - 6.6e-17 61.6 0.0 8.9e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Aminotran_1_2 PF00155.21 KXZ55904.1 - 0.14 11.2 0.0 1.2 8.3 0.0 1.9 1 1 0 1 1 1 0 Aminotransferase class I and II PAF-AH_p_II PF03403.13 KXZ55905.1 - 6.8e-42 143.3 0.0 5.7e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXZ55905.1 - 8e-08 31.5 0.0 0.0035 16.3 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXZ55905.1 - 8.1e-06 25.3 0.9 0.055 12.7 0.0 2.6 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXZ55905.1 - 1.6e-05 24.1 1.0 0.038 13.0 0.1 2.6 3 0 0 3 3 3 2 Chlorophyllase Abhydrolase_1 PF00561.20 KXZ55905.1 - 2.9e-05 23.8 0.0 0.0025 17.5 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXZ55905.1 - 0.00011 21.8 0.1 0.0003 20.3 0.1 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXZ55905.1 - 0.00081 19.0 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KXZ55905.1 - 0.051 13.1 1.4 0.062 12.9 0.0 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KXZ55905.1 - 0.19 10.4 0.1 0.59 8.7 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Cation_ATPase_C PF00689.21 KXZ55906.1 - 1.4e-43 148.8 0.9 4.4e-43 147.1 0.9 1.9 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXZ55906.1 - 9.9e-40 136.0 0.3 9.9e-40 136.0 0.3 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXZ55906.1 - 4.1e-20 73.0 0.0 1.2e-19 71.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ55906.1 - 4.8e-14 52.2 0.1 9e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXZ55906.1 - 6.6e-06 26.0 1.4 0.00018 21.3 0.7 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ55906.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Spc7 PF08317.11 KXZ55907.1 - 1.1e-07 31.0 11.4 3.5e-07 29.4 11.4 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein COG2 PF06148.11 KXZ55907.1 - 0.039 14.1 0.4 0.039 14.1 0.4 3.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_TATA_bd PF12325.8 KXZ55907.1 - 5.7 7.2 16.3 1.7 8.9 1.1 3.5 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CorA PF01544.18 KXZ55907.1 - 7 5.9 7.0 12 5.1 7.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ABC_tran_CTD PF16326.5 KXZ55907.1 - 9.6 6.5 18.3 0.093 13.0 1.5 4.2 3 1 0 4 4 4 0 ABC transporter C-terminal domain EF-hand_7 PF13499.6 KXZ55908.1 - 2.3e-21 76.0 0.1 2e-11 44.2 0.2 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KXZ55908.1 - 1.2e-16 58.9 3.8 0.0003 20.1 0.4 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KXZ55908.1 - 1.3e-16 59.1 0.9 9.1e-05 22.1 0.5 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KXZ55908.1 - 9.5e-13 47.0 2.6 3e-05 23.3 0.5 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KXZ55908.1 - 1.1e-10 41.2 1.5 0.0091 15.8 0.0 3.7 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXZ55908.1 - 0.039 14.3 0.0 9.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1499 PF07386.11 KXZ55909.1 - 1.9e-33 115.5 0.0 2.7e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) CCDC71L PF15374.6 KXZ55909.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DEAD PF00270.29 KXZ55910.1 - 3.7e-49 166.9 0.2 5e-49 166.4 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ55910.1 - 1.6e-22 79.9 0.0 3.6e-21 75.6 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KXZ55910.1 - 0.0026 17.2 0.1 0.017 14.5 0.0 1.9 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KXZ55910.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Histone_H2A_C PF16211.5 KXZ55912.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ55912.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ55912.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ55913.1 - 2.5e-21 76.4 5.3 3.5e-21 75.9 5.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ55913.1 - 2.5e-05 24.5 0.1 8.3e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ55913.1 - 0.0019 18.7 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ55913.1 - 0.023 14.4 0.2 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ55913.1 - 0.023 14.7 7.8 0.11 12.5 7.8 1.9 1 1 0 1 1 1 0 YscO-like protein DUF3391 PF11871.8 KXZ55913.1 - 5 7.7 8.6 16 6.0 8.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) CENP-T_C PF15511.6 KXZ55914.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ55914.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ55914.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ55914.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ55914.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ55914.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ55914.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Suf PF05843.14 KXZ55915.1 - 1.1e-31 110.9 0.0 3.2e-26 93.0 0.0 4.5 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KXZ55915.1 - 1.9e-10 41.1 5.2 0.018 15.5 0.2 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ55915.1 - 0.0014 19.2 30.8 3.6 8.7 0.0 8.4 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ55915.1 - 0.0054 17.0 0.0 0.022 15.1 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ55915.1 - 0.018 14.3 0.3 0.018 14.3 0.3 3.2 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ55915.1 - 0.03 14.3 3.4 0.86 9.8 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ55915.1 - 0.068 13.5 7.5 7 7.0 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KXZ55915.1 - 0.12 11.4 0.4 42 3.1 0.0 3.6 4 1 0 4 4 4 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KXZ55915.1 - 0.15 12.8 11.0 18 6.3 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat MTH865 PF07747.11 KXZ55915.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 MTH865-like family WD40 PF00400.32 KXZ55916.1 - 0.81 10.7 7.8 1.7 9.6 0.1 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat NIF PF03031.18 KXZ55917.1 - 2.1e-39 134.8 0.0 4.1e-39 133.9 0.0 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase TPT PF03151.16 KXZ55918.1 - 8.9e-30 104.0 20.9 1e-29 103.8 20.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXZ55918.1 - 6.1e-12 45.4 23.1 7.5e-12 45.1 23.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXZ55918.1 - 1.2e-07 32.0 30.5 0.00058 20.0 8.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family Arb1 PF09692.10 KXZ55919.1 - 0.16 11.1 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Fasciclin PF02469.22 KXZ55921.1 - 2.8e-05 24.4 0.0 4.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Cpn10 PF00166.21 KXZ55922.1 - 1.2e-47 159.9 0.2 1.4e-25 89.2 0.0 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit MS_channel PF00924.18 KXZ55923.1 - 2.8e-13 49.9 0.0 4.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXZ55923.1 - 0.00027 20.3 0.1 0.00045 19.6 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ55923.1 - 0.0032 17.3 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ55923.1 - 0.017 15.6 0.1 0.037 14.5 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KXZ55923.1 - 0.034 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KXZ55923.1 - 0.19 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair RNA_POL_M_15KD PF02150.16 KXZ55924.1 - 3.4e-08 33.2 2.7 3.4e-08 33.2 2.7 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KXZ55924.1 - 7.1e-07 29.0 4.4 7.1e-07 29.0 4.4 2.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) Elf1 PF05129.13 KXZ55924.1 - 0.0074 16.3 4.6 0.016 15.2 0.2 2.3 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 KXZ55924.1 - 0.015 15.3 1.1 0.015 15.3 1.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 KXZ55924.1 - 0.039 13.9 0.1 0.039 13.9 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Fer4_21 PF14697.6 KXZ55924.1 - 0.091 12.9 0.2 0.091 12.9 0.2 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Lar_restr_allev PF14354.6 KXZ55924.1 - 0.18 12.2 6.7 0.6 10.5 1.4 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Anti-TRAP PF15777.5 KXZ55924.1 - 0.37 10.8 3.3 2.6 8.1 0.1 2.6 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DpnI PF06044.12 KXZ55924.1 - 0.92 9.1 5.3 3.4 7.3 0.4 2.1 2 0 0 2 2 2 0 Dam-replacing family Fer4_10 PF13237.6 KXZ55924.1 - 1.3 9.2 10.3 0.86 9.8 1.7 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain zinc_ribbon_10 PF10058.9 KXZ55924.1 - 2.6 7.9 11.7 5.5 6.8 1.5 2.6 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Dof PF02701.15 KXZ55924.1 - 2.8 8.2 9.2 0.67 10.1 2.2 2.5 2 1 0 2 2 2 0 Dof domain, zinc finger Ribosomal_S27e PF01667.17 KXZ55924.1 - 6.5 6.6 9.2 0.29 10.9 2.7 2.1 2 1 0 2 2 2 0 Ribosomal protein S27 zf-ribbon_3 PF13248.6 KXZ55924.1 - 8.2 6.0 12.1 0.9 9.0 0.3 3.7 4 0 0 4 4 4 0 zinc-ribbon domain TBP PF00352.21 KXZ55925.1 - 1.7e-55 184.9 0.2 2.2e-30 104.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KXZ55925.1 - 0.0017 18.4 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) NS3_envE PF02723.14 KXZ55925.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Cnn_1N PF07989.11 KXZ55926.1 - 0.02 15.0 1.1 0.02 15.0 1.1 2.3 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 TPD52 PF04201.15 KXZ55926.1 - 0.14 11.8 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 Tumour protein D52 family DivIC PF04977.15 KXZ55926.1 - 0.28 11.0 18.0 0.1 12.4 2.4 3.3 3 0 0 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 KXZ55926.1 - 5.7 6.2 5.0 25 4.1 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) HALZ PF02183.18 KXZ55926.1 - 6.4 7.1 8.5 1.3 9.3 0.8 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper CENP-T_C PF15511.6 KXZ55927.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ55927.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ55927.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ55927.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ55927.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ55927.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ55927.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ55928.1 - 1.6e-21 77.0 4.6 2.2e-21 76.6 4.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ55928.1 - 2.6e-05 24.4 0.1 8.3e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ55928.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KXZ55928.1 - 0.023 14.3 0.2 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Replication protein C N-terminal domain YscO-like PF16789.5 KXZ55928.1 - 0.028 14.4 8.0 0.14 12.2 8.0 1.9 1 1 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 KXZ55929.1 - 3.1e-19 68.4 2.2 5.7e-19 67.6 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ55929.1 - 6.6e-17 62.1 0.0 8.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ55929.1 - 3.5e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CN_hydrolase PF00795.22 KXZ55930.1 - 1.3e-60 204.9 0.0 1.6e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HSCB_C PF07743.13 KXZ55931.1 - 1.5e-12 47.8 0.6 2.4e-12 47.1 0.6 1.3 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KXZ55931.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain SNARE PF05739.19 KXZ55932.1 - 5e-14 52.0 2.0 5e-14 52.0 2.0 2.4 4 0 0 4 4 4 1 SNARE domain Synaptobrevin PF00957.21 KXZ55932.1 - 0.00059 19.6 3.9 0.00059 19.6 3.9 1.9 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.21 KXZ55932.1 - 0.0038 17.1 1.5 0.0038 17.1 1.5 2.4 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain COG5 PF10392.9 KXZ55932.1 - 0.014 15.6 7.7 0.15 12.3 0.7 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Orf78 PF06024.12 KXZ55932.1 - 0.052 13.8 0.5 0.12 12.7 0.5 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF2209 PF09974.9 KXZ55932.1 - 0.14 12.4 4.3 0.39 11.1 0.8 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) LXG PF04740.12 KXZ55932.1 - 0.15 11.7 6.8 2.7 7.6 2.0 2.4 2 1 0 2 2 2 0 LXG domain of WXG superfamily Syntaxin PF00804.25 KXZ55932.1 - 0.18 11.4 18.2 0.42 10.2 13.2 2.7 2 1 0 2 2 2 0 Syntaxin Prp19 PF08606.11 KXZ55932.1 - 0.35 10.9 2.9 0.44 10.6 0.6 2.5 2 1 1 3 3 3 0 Prp19/Pso4-like DUF2564 PF10819.8 KXZ55932.1 - 1.3 9.5 6.3 3.1 8.2 2.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) EF-G-binding_N PF07299.11 KXZ55932.1 - 1.5 9.4 7.1 1.8 9.2 0.1 2.9 2 1 1 3 3 3 0 Elongation factor G-binding protein, N-terminal T3SS_needle_E PF08988.10 KXZ55932.1 - 3 8.1 6.0 6 7.1 1.5 3.0 2 2 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle MlaD PF02470.20 KXZ55933.1 - 3.6e-10 40.0 0.0 5.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 MlaD protein AMP-binding PF00501.28 KXZ55934.1 - 2.6e-97 326.1 0.0 3e-97 325.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ55934.1 - 0.00011 23.1 0.0 0.00028 21.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_GP20 PF06810.11 KXZ55935.1 - 0.45 10.3 5.3 0.084 12.7 1.1 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 TBCA PF02970.16 KXZ55935.1 - 3 8.2 5.3 11 6.4 0.1 2.7 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF3535 PF12054.8 KXZ55935.1 - 8.6 5.5 7.1 15 4.7 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Ribosomal_S8e PF01201.22 KXZ55936.1 - 1.6e-46 157.9 1.3 2.8e-46 157.1 1.3 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e SOG2 PF10428.9 KXZ55938.1 - 0.64 9.2 1.9 0.83 8.8 1.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CENP-T_C PF15511.6 KXZ55939.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ55939.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ55939.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ55939.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ55939.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ55939.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ55939.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ55940.1 - 4.4e-22 78.8 4.0 5.8e-22 78.4 4.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ55940.1 - 2.7e-05 24.4 0.1 8.3e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXZ55940.1 - 0.0019 18.7 0.0 0.0031 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KXZ55940.1 - 0.014 15.5 4.6 0.028 14.5 4.6 1.6 1 1 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KXZ55940.1 - 0.029 14.0 0.7 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KXZ55941.1 - 3.3e-19 68.3 2.2 5.7e-19 67.6 2.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXZ55941.1 - 1.4e-16 61.0 0.0 1.8e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXZ55941.1 - 6.4e-05 23.2 0.0 9.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SHIPPO-rpt PF07004.12 KXZ55942.1 - 1.6e-14 54.0 44.1 0.0002 22.1 0.5 8.9 8 0 0 8 8 8 6 Sperm-tail PG-rich repeat ARID PF01388.21 KXZ55943.1 - 1.4e-11 44.9 0.0 1.4e-11 44.9 0.0 3.0 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain DNMT1-RFD PF12047.8 KXZ55943.1 - 7e-10 39.1 0.0 1.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain WHIM1 PF15612.6 KXZ55943.1 - 2.7e-07 29.9 0.0 6.5e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Auxin_resp PF06507.13 KXZ55943.1 - 0.011 16.0 0.0 0.088 13.1 0.0 2.4 3 0 0 3 3 3 0 Auxin response factor STI1 PF17830.1 KXZ55944.1 - 4.6e-13 48.9 1.7 4.6e-13 48.9 1.7 4.7 4 1 0 4 4 4 3 STI1 domain RPN13_C PF16550.5 KXZ55944.1 - 3.1e-07 30.5 0.4 7.5e-07 29.3 0.4 1.7 1 0 0 1 1 1 1 UCH-binding domain Com_YlbF PF06133.11 KXZ55944.1 - 3.1 8.5 7.0 99 3.6 4.8 3.2 3 1 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA EamA PF00892.20 KXZ55945.1 - 2.3e-38 131.5 27.3 8.6e-19 68.1 5.6 3.1 2 1 0 2 2 2 2 EamA-like transporter family Amidase_6 PF12671.7 KXZ55946.1 - 0.011 15.9 0.2 0.015 15.4 0.2 1.1 1 0 0 1 1 1 0 Putative amidase domain Pkinase_Tyr PF07714.17 KXZ55947.1 - 7.5e-49 166.3 0.0 5.3e-32 111.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ55947.1 - 2.2e-48 165.0 0.0 6.9e-47 160.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 KXZ55947.1 - 2.1e-09 37.5 0.1 6.2e-07 29.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ55947.1 - 1.7e-08 34.9 0.0 5.2e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ55947.1 - 1e-06 29.1 0.0 2.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ55947.1 - 4.4e-06 26.6 0.0 6.9e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXZ55947.1 - 9.1e-05 22.7 0.0 0.0006 20.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat APH PF01636.23 KXZ55947.1 - 0.03 14.3 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ55947.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase AAA_lid_2 PF17863.1 KXZ55947.1 - 0.16 11.9 0.2 4 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA lid domain DnaJ_C PF01556.18 KXZ55948.1 - 2.2e-36 125.2 0.0 3.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KXZ55948.1 - 2.7e-11 43.6 14.1 4.9e-11 42.8 14.1 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KXZ55948.1 - 7.5e-08 32.4 0.0 1.9e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain Anti-TRAP PF15777.5 KXZ55948.1 - 0.00017 21.5 12.2 0.01 15.8 2.8 3.4 1 1 2 3 3 3 3 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KXZ55948.1 - 0.023 14.7 7.0 0.057 13.4 7.0 1.7 1 0 0 1 1 1 0 zinc-ribbons NRDD PF13597.6 KXZ55948.1 - 0.24 10.1 8.3 0.13 11.0 1.2 2.1 1 1 1 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase DZR PF12773.7 KXZ55948.1 - 1.8 8.7 14.2 0.58 10.2 3.0 2.3 1 1 2 3 3 3 0 Double zinc ribbon zf-IS66 PF13005.7 KXZ55948.1 - 5.7 7.4 8.8 13 6.3 0.2 3.6 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.6 KXZ55948.1 - 8.4 6.9 8.7 10 6.6 0.2 2.8 2 1 1 3 3 3 0 Restriction alleviation protein Lar PRIMA1 PF16101.5 KXZ55949.1 - 0.78 9.8 5.2 1.8 8.6 5.2 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SNF2_N PF00176.23 KXZ55950.1 - 2.3e-74 250.2 0.2 5.2e-74 249.1 0.2 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KXZ55950.1 - 2e-48 163.1 3.2 2e-48 163.1 3.2 2.7 4 0 0 4 4 4 1 SLIDE Helicase_C PF00271.31 KXZ55950.1 - 2.5e-19 69.6 0.0 1.1e-18 67.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HAND PF09110.11 KXZ55950.1 - 3.9e-13 50.1 3.2 3.9e-13 50.1 3.2 3.0 3 1 0 3 3 1 1 HAND ResIII PF04851.15 KXZ55950.1 - 8.5e-11 42.1 3.5 8.7e-11 42.1 0.0 2.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 KXZ55950.1 - 1.6e-08 34.6 0.2 0.00054 20.1 0.1 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.29 KXZ55950.1 - 1.9e-08 34.3 0.0 6.7e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KXZ55950.1 - 0.00016 20.9 0.0 0.00048 19.4 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KXZ55950.1 - 0.0019 17.9 0.0 0.0059 16.3 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DBINO PF13892.6 KXZ55950.1 - 0.0086 16.4 0.4 0.0086 16.4 0.4 3.4 3 1 0 3 3 3 1 DNA-binding domain DUF1086 PF06461.11 KXZ55950.1 - 0.067 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) KH_8 PF17903.1 KXZ55951.1 - 4.5e-31 106.8 0.1 1.9e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KXZ55951.1 - 0.0021 17.8 0.0 0.0083 15.9 0.0 2.1 2 1 0 2 2 2 1 KH domain Hamartin PF04388.12 KXZ55951.1 - 0.076 11.7 0.5 0.11 11.2 0.5 1.1 1 0 0 1 1 1 0 Hamartin protein Borrelia_P83 PF05262.11 KXZ55951.1 - 1.1 7.7 6.1 1.8 7.0 6.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.25 KXZ55952.1 - 5e-72 242.4 0.0 6e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ55952.1 - 3.2e-34 118.4 0.0 5.4e-34 117.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXZ55952.1 - 5.3e-05 22.7 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXZ55952.1 - 0.00059 18.9 0.1 0.00087 18.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXZ55952.1 - 0.0012 18.2 0.1 0.019 14.3 0.0 2.7 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KXZ55952.1 - 0.062 13.2 0.1 0.36 10.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PsbP PF01789.16 KXZ55953.1 - 1.8e-42 145.1 0.1 2.2e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 PsbP PsbQ PF05757.11 KXZ55953.1 - 0.039 13.7 0.5 0.069 12.9 0.5 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) PepSY PF03413.19 KXZ55953.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain LLC1 PF14945.6 KXZ55954.1 - 0.0015 19.1 0.1 0.0029 18.2 0.1 1.4 1 1 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF489 PF04356.12 KXZ55955.1 - 0.0044 17.0 0.9 0.0079 16.2 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF489) HIP1_clath_bdg PF16515.5 KXZ55955.1 - 0.02 15.5 14.3 0.023 15.3 12.5 1.9 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 KXZ55955.1 - 0.15 9.9 1.7 0.19 9.6 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 KXZ55955.1 - 0.16 12.5 17.7 0.036 14.6 14.1 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 KXZ55955.1 - 0.17 10.8 15.7 0.23 10.3 15.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Rogdi_lz PF10259.9 KXZ55955.1 - 0.25 10.7 1.4 0.39 10.1 1.4 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Golgin_A5 PF09787.9 KXZ55955.1 - 0.39 10.1 12.2 0.57 9.6 12.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 JIP_LZII PF16471.5 KXZ55955.1 - 0.4 10.9 3.0 0.92 9.7 2.7 1.8 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Filament PF00038.21 KXZ55955.1 - 0.52 9.9 16.4 1.4 8.4 9.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein AAA_13 PF13166.6 KXZ55955.1 - 0.7 8.5 7.8 0.97 8.0 7.8 1.1 1 0 0 1 1 1 0 AAA domain KLRAQ PF10205.9 KXZ55955.1 - 0.85 9.9 7.4 1.6 9.0 3.7 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Laminin_II PF06009.12 KXZ55955.1 - 0.96 9.5 11.4 1.8 8.6 10.9 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.6 KXZ55955.1 - 1.1 8.6 19.1 1.6 8.0 19.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 KXZ55955.1 - 1.4 9.4 17.9 1.9 8.9 4.0 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.11 KXZ55955.1 - 1.4 9.1 22.2 0.083 13.1 16.7 1.7 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) DUF4763 PF15960.5 KXZ55955.1 - 1.5 8.1 11.8 0.58 9.4 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) FapA PF03961.13 KXZ55955.1 - 1.6 7.3 3.8 2 7.0 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4472 PF14739.6 KXZ55955.1 - 1.9 9.2 14.7 0.33 11.7 7.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Atg14 PF10186.9 KXZ55955.1 - 2.2 7.3 13.1 3.4 6.7 13.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KXZ55955.1 - 2.3 7.5 15.2 3.1 7.1 4.4 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SLX9 PF15341.6 KXZ55955.1 - 4.9 7.6 9.7 1.6 9.1 6.0 1.9 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 ERM PF00769.19 KXZ55955.1 - 5.4 6.7 25.5 24 4.7 25.5 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family PRKG1_interact PF15898.5 KXZ55955.1 - 6.6 7.7 11.4 3.4 8.6 1.8 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Rootletin PF15035.6 KXZ55955.1 - 7.5 6.5 15.5 33 4.4 15.5 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 KXZ55956.1 - 0.077 13.6 2.8 0.082 13.5 1.6 1.6 1 1 1 2 2 2 0 SlyX Enkurin PF13864.6 KXZ55957.1 - 0.002 18.5 0.1 0.0023 18.3 0.1 1.2 1 0 0 1 1 1 1 Calmodulin-binding ORF11CD3 PF10549.9 KXZ55957.1 - 0.073 13.2 0.4 0.14 12.3 0.4 1.6 1 1 0 1 1 1 0 ORF11CD3 domain Thioredoxin PF00085.20 KXZ55958.1 - 4.5e-10 39.5 0.0 6.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXZ55958.1 - 4.6e-05 23.8 0.0 0.00012 22.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXZ55958.1 - 0.0009 19.5 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXZ55958.1 - 0.0067 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KXZ55958.1 - 0.0091 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF3676 PF12429.8 KXZ55958.1 - 0.19 11.5 4.4 0.15 11.9 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3676) Ribonuc_red_sm PF00268.21 KXZ55961.1 - 1.2e-112 376.0 0.0 1.4e-112 375.7 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Haem_oxygenas_2 PF14518.6 KXZ55961.1 - 0.022 14.6 0.2 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Iron-containing redox enzyme EF-hand_7 PF13499.6 KXZ55962.1 - 2.9e-07 30.8 0.4 1.3e-06 28.8 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ55962.1 - 1.5e-06 27.3 0.0 0.0039 16.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXZ55962.1 - 2.2e-05 24.0 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KXZ55962.1 - 0.011 15.5 0.0 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KXZ55962.1 - 0.11 12.1 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 EF hand Myosin_tail_1 PF01576.19 KXZ55964.1 - 0.0043 15.0 3.2 0.005 14.7 3.2 1.0 1 0 0 1 1 1 1 Myosin tail OmpH PF03938.14 KXZ55964.1 - 0.017 15.5 5.1 0.02 15.3 5.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ADIP PF11559.8 KXZ55964.1 - 0.018 15.1 2.8 0.029 14.5 2.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding T2SSK PF03934.13 KXZ55964.1 - 0.02 14.3 0.7 0.024 14.0 0.7 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K CENP-Q PF13094.6 KXZ55964.1 - 0.027 14.7 3.1 0.035 14.3 3.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2408 PF10303.9 KXZ55964.1 - 0.027 15.0 1.0 0.035 14.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) APG6_N PF17675.1 KXZ55964.1 - 0.046 14.3 5.2 0.068 13.7 5.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 KXZ55964.1 - 0.051 13.5 3.5 0.066 13.1 3.5 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain KinB_sensor PF16767.5 KXZ55964.1 - 0.08 13.4 1.3 0.13 12.7 0.8 1.5 1 1 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB ATG16 PF08614.11 KXZ55964.1 - 0.14 12.4 6.7 0.062 13.5 3.8 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KXZ55964.1 - 0.17 12.6 2.8 2 9.1 0.0 2.5 1 1 1 2 2 2 0 SlyX SseC PF04888.12 KXZ55964.1 - 0.19 11.3 4.0 0.42 10.2 4.0 1.6 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4404 PF14357.6 KXZ55964.1 - 2.2 9.0 4.9 15 6.3 4.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Peptidase_M16 PF00675.20 KXZ55965.1 - 1.8e-18 67.0 0.1 2.9e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXZ55965.1 - 2e-14 54.0 0.0 7.4e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Amino_oxidase PF01593.24 KXZ55966.1 - 2.2e-78 264.6 0.0 2.6e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ55966.1 - 7.3e-14 51.8 0.1 1.4e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXZ55966.1 - 2.2e-06 28.1 0.1 0.038 14.5 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXZ55966.1 - 8.4e-06 25.6 0.0 0.024 14.2 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ55966.1 - 1.1e-05 24.8 0.0 0.0017 17.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ55966.1 - 0.00064 18.9 1.3 0.001 18.2 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KXZ55966.1 - 0.0012 18.2 0.5 0.0058 15.9 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain MCRA PF06100.11 KXZ55966.1 - 0.0014 17.5 0.0 0.049 12.4 0.0 2.1 2 0 0 2 2 2 1 MCRA family Trp_halogenase PF04820.14 KXZ55966.1 - 0.0035 16.3 0.2 1.7 7.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 KXZ55966.1 - 0.0076 15.5 0.2 0.013 14.7 0.2 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KXZ55966.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXZ55966.1 - 0.024 13.3 0.5 0.098 11.3 0.9 1.8 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KXZ55966.1 - 0.047 13.0 0.1 0.083 12.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXZ55966.1 - 0.14 11.2 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KXZ55966.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain dCMP_cyt_deam_1 PF00383.23 KXZ55967.1 - 5.1e-10 39.1 0.8 6.9e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXZ55967.1 - 1.2e-06 28.4 0.7 2.1e-06 27.5 0.1 1.7 1 1 1 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXZ55967.1 - 0.1 12.7 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase PDEase_I PF00233.19 KXZ55968.1 - 5.3e-77 258.7 0.1 7.3e-77 258.3 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase EF-hand_8 PF13833.6 KXZ55969.1 - 9.7e-13 47.8 1.2 9e-09 35.1 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXZ55969.1 - 3.3e-11 41.9 0.2 0.00019 20.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXZ55969.1 - 1.1e-10 40.5 0.1 2.6e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXZ55969.1 - 2.2e-10 40.8 0.2 5.4e-10 39.6 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair cNMP_binding PF00027.29 KXZ55969.1 - 5.9e-09 35.9 0.0 0.12 12.5 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain EF-hand_5 PF13202.6 KXZ55969.1 - 6.5e-08 31.7 0.7 9.7e-05 21.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KXZ55969.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Nucleotid_trans PF03407.16 KXZ55971.1 - 0.0055 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Vps36-NZF-N PF16988.5 KXZ55972.1 - 0.012 14.9 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn-ribbon_8 PF09723.10 KXZ55972.1 - 0.041 14.0 0.2 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_3 PF13878.6 KXZ55972.1 - 0.042 13.7 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-ribbon_3 PF13248.6 KXZ55972.1 - 0.043 13.2 1.8 5.4 6.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 KXZ55972.1 - 0.044 13.7 0.6 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KXZ55972.1 - 0.063 13.0 2.8 1.3 8.8 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain TFIIS_C PF01096.18 KXZ55972.1 - 0.068 13.0 0.4 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.6 KXZ55972.1 - 1.7 8.4 4.9 10 6.0 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KXZ55972.1 - 2.7 7.8 5.7 11 5.8 0.2 2.6 3 0 0 3 3 3 0 A2L zinc ribbon domain SpoU_methylase PF00588.19 KXZ55973.1 - 0.041 14.0 0.0 0.047 13.9 0.0 1.1 1 0 0 1 1 1 0 SpoU rRNA Methylase family XdhC_C PF13478.6 KXZ55973.1 - 0.042 14.4 0.1 0.053 14.0 0.1 1.0 1 0 0 1 1 1 0 XdhC Rossmann domain GST_N_3 PF13417.6 KXZ55975.1 - 2.6e-14 53.4 0.0 4.2e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXZ55975.1 - 1.7e-08 34.6 0.0 3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXZ55975.1 - 1.4e-07 31.4 0.8 2.7e-07 30.5 0.8 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXZ55975.1 - 2.4e-07 31.0 0.0 4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXZ55975.1 - 4.7e-07 30.4 0.1 7.5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXZ55975.1 - 1.9e-05 24.8 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXZ55975.1 - 3.5e-05 23.9 0.0 5.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BPL_N PF09825.9 KXZ55976.1 - 1.5e-42 146.0 2.8 1.9e-34 119.4 0.1 3.8 4 1 0 4 4 4 2 Biotin-protein ligase, N terminal DUF812 PF05667.11 KXZ55976.1 - 0.074 11.9 31.3 0.13 11.1 31.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Chloroa_b-bind PF00504.21 KXZ55977.1 - 1.4e-38 132.9 0.2 2e-38 132.5 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Glyco_transf_64 PF09258.10 KXZ55978.1 - 3.5e-54 183.7 0.0 4.3e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain AMNp_N PF10423.9 KXZ55978.1 - 0.19 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus TPR_2 PF07719.17 KXZ55979.1 - 9.7e-06 25.3 0.0 0.049 13.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ55979.1 - 0.0003 21.3 2.4 0.0044 17.6 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF493 PF04359.14 KXZ55980.1 - 3.1e-15 56.5 0.0 4.2e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF493) Peptidase_M20 PF01546.28 KXZ55981.1 - 3.4e-30 105.3 0.0 5.5e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXZ55981.1 - 1.3e-12 47.6 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXZ55981.1 - 0.00071 19.3 0.0 0.00071 19.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 XPC-binding PF09280.11 KXZ55981.1 - 0.032 14.0 0.3 1.7 8.5 0.0 2.6 3 0 0 3 3 3 0 XPC-binding domain Pkinase_Tyr PF07714.17 KXZ55982.1 - 1.4e-05 24.6 0.2 7.5e-05 22.1 0.3 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ55982.1 - 0.0012 18.2 0.0 0.0033 16.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain zf-MYND PF01753.18 KXZ55983.1 - 3.8e-09 36.5 8.3 7.8e-09 35.5 8.3 1.5 1 0 0 1 1 1 1 MYND finger WD40 PF00400.32 KXZ55983.1 - 4.5e-05 24.1 7.0 0.17 12.8 0.2 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat SUIM_assoc PF16619.5 KXZ55983.1 - 0.016 15.3 1.2 0.034 14.2 1.2 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Mcl1_mid PF12341.8 KXZ55983.1 - 0.11 11.8 0.2 0.36 10.1 0.1 1.7 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Homeobox_KN PF05920.11 KXZ55984.1 - 1.6e-15 56.7 0.0 3.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXZ55984.1 - 0.0014 18.4 0.1 0.0033 17.2 0.0 1.7 2 0 0 2 2 2 1 Homeodomain EF-hand_5 PF13202.6 KXZ55985.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 EF hand DUF5345 PF17280.2 KXZ55985.1 - 0.039 13.9 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Glycophorin_A PF01102.18 KXZ55985.1 - 0.057 13.7 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A DUF3270 PF11674.8 KXZ55985.1 - 0.12 12.6 0.2 0.2 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) EF-hand_1 PF00036.32 KXZ55985.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 EF hand Excalibur PF05901.11 KXZ55985.1 - 0.2 12.3 0.0 0.36 11.5 0.0 1.4 1 0 0 1 1 1 0 Excalibur calcium-binding domain Hint PF01079.20 KXZ55986.1 - 6.1e-10 39.0 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 KXZ55986.1 - 0.029 14.7 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Hint domain Pantoate_transf PF02548.15 KXZ55987.1 - 2.4e-107 358.2 0.2 3.4e-107 357.7 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KXZ55987.1 - 0.0065 16.0 0.3 0.0065 16.0 0.3 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase SICA_alpha PF12887.7 KXZ55988.1 - 0.049 13.5 0.7 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 SICA extracellular alpha domain Hemerythrin PF01814.23 KXZ55988.1 - 0.26 11.9 6.9 1.2 9.8 1.0 3.3 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain Cortex-I_coil PF09304.10 KXZ55988.1 - 0.33 11.2 3.4 0.79 10.0 2.5 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil T3SS_needle_F PF09392.10 KXZ55988.1 - 0.44 10.8 2.1 5.1 7.4 0.0 3.7 5 0 0 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF UCH PF00443.29 KXZ55989.1 - 4.3e-16 59.2 0.0 1.1e-15 57.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ55989.1 - 2.6e-07 30.6 0.0 1e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Macoilin PF09726.9 KXZ55989.1 - 0.87 8.1 13.6 1.3 7.5 13.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF4746 PF15928.5 KXZ55989.1 - 2.5 7.4 16.4 4.6 6.6 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 KXZ55989.1 - 3.9 7.2 18.6 8.1 6.2 18.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 KXZ55989.1 - 4 6.3 7.9 6.7 5.5 7.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF760 PF05542.11 KXZ55990.1 - 2.2e-14 53.6 0.0 4.7e-12 46.1 0.0 3.0 2 2 0 2 2 2 1 Protein of unknown function (DUF760) DUF4507 PF14964.6 KXZ55990.1 - 0.16 10.9 0.6 0.85 8.5 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4507) FlxA PF14282.6 KXZ55990.1 - 0.22 11.5 2.3 2 8.5 0.0 2.5 2 0 0 2 2 2 0 FlxA-like protein TPR_19 PF14559.6 KXZ55991.1 - 1.9e-09 37.9 5.8 6.6e-07 29.7 0.5 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ55991.1 - 8.3e-08 31.8 0.3 0.0032 17.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ55991.1 - 1.1e-06 28.2 0.0 0.0017 18.0 0.0 2.2 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.6 KXZ55991.1 - 3e-06 27.8 9.7 0.0031 18.1 0.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ55991.1 - 5e-05 23.8 8.4 0.094 13.6 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ55991.1 - 0.00025 20.7 0.0 2.4 8.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ55991.1 - 0.00041 20.6 2.8 0.012 15.9 0.3 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ55991.1 - 0.0007 19.8 0.1 0.07 13.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KXZ55991.1 - 0.0041 17.6 6.8 0.59 10.6 2.3 2.1 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_8 PF13181.6 KXZ55991.1 - 0.0068 16.5 0.0 12 6.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ55991.1 - 0.023 14.9 0.0 0.22 11.8 0.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXZ55991.1 - 0.034 14.2 0.5 51 4.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ55991.1 - 0.069 13.3 5.4 0.64 10.2 5.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4398 PF14346.6 KXZ55991.1 - 0.1 13.2 4.2 5.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) TPR_4 PF07721.14 KXZ55991.1 - 0.12 13.0 14.9 1.3 9.9 1.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Rubrerythrin PF02915.17 KXZ55992.1 - 9.8e-41 139.4 0.2 2.3e-40 138.1 0.0 1.7 2 0 0 2 2 2 1 Rubrerythrin FA_desaturase_2 PF03405.14 KXZ55992.1 - 0.016 14.1 0.0 4.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DUF4812 PF16071.5 KXZ55992.1 - 0.026 14.3 0.7 0.082 12.7 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) RNA_pol_Rpb5_N PF03871.14 KXZ55992.1 - 0.11 13.1 0.4 0.59 10.8 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain Syndecan PF01034.20 KXZ55992.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Peptidase_C54 PF03416.19 KXZ55993.1 - 2.2e-46 158.5 0.0 3.2e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 WD40 PF00400.32 KXZ55994.1 - 3e-19 69.0 5.6 1.7e-05 25.4 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ55994.1 - 0.00016 21.9 0.1 0.22 11.9 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXZ55994.1 - 0.023 13.4 0.1 0.59 8.7 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 ELYS-bb PF16687.5 KXZ55994.1 - 0.12 10.9 0.1 0.4 9.2 0.0 1.8 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin bZIP_2 PF07716.15 KXZ55995.1 - 0.22 11.6 1.1 0.31 11.2 1.1 1.2 1 0 0 1 1 1 0 Basic region leucine zipper DUF202 PF02656.15 KXZ55996.1 - 0.00023 21.5 0.8 0.0049 17.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Adeno_E3_CR2 PF02439.15 KXZ55996.1 - 0.21 11.4 4.1 0.21 11.3 0.1 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 UQ_con PF00179.26 KXZ55997.1 - 3.5e-24 85.0 0.0 5.3e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KXZ55997.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain Ufd2P_core PF10408.9 KXZ55998.1 - 1.5e-26 93.2 0.0 7.1e-19 67.9 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin elongating factor core SgrR_N PF12793.7 KXZ55998.1 - 0.19 11.9 0.0 0.47 10.7 0.0 1.6 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term UIM PF02809.20 KXZ55998.1 - 0.21 11.6 5.2 0.6 10.2 5.2 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Ribosomal_S28e PF01200.18 KXZ55999.1 - 9.5e-33 112.0 1.2 1e-32 111.9 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e OrfB_Zn_ribbon PF07282.11 KXZ56000.1 - 0.01 15.7 0.4 0.019 14.9 0.4 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-HIT PF04438.16 KXZ56000.1 - 0.014 15.3 0.6 0.014 15.3 0.6 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C2HC5 PF06221.13 KXZ56000.1 - 0.02 14.9 0.7 0.039 13.9 0.7 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Rubredoxin PF00301.20 KXZ56000.1 - 0.021 14.9 14.0 0.46 10.6 10.9 2.8 2 1 0 2 2 2 0 Rubredoxin PDZ PF00595.24 KXZ56000.1 - 0.026 14.9 0.4 0.048 14.0 0.4 1.4 1 0 0 1 1 1 0 PDZ domain Zn-ribbon_8 PF09723.10 KXZ56000.1 - 0.041 14.0 2.6 0.053 13.6 1.6 1.7 2 0 0 2 2 2 0 Zinc ribbon domain PDZ_6 PF17820.1 KXZ56000.1 - 0.095 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 PDZ domain HypA PF01155.19 KXZ56000.1 - 0.19 11.8 0.3 0.33 11.0 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0547 PF10571.9 KXZ56000.1 - 1.7 8.8 4.5 28 4.9 0.9 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 SET PF00856.28 KXZ56001.1 - 0.0013 19.1 0.0 0.0058 17.0 0.0 2.1 1 1 1 2 2 2 1 SET domain Pkinase PF00069.25 KXZ56002.1 - 1.2e-29 103.6 0.0 5e-29 101.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56002.1 - 4.3e-13 49.1 0.0 8e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ56002.1 - 0.014 14.7 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Med27 PF11571.8 KXZ56003.1 - 0.00049 20.4 0.0 0.00098 19.4 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 AAA_lid_2 PF17863.1 KXZ56004.1 - 4.6e-17 61.6 0.8 1.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 AAA lid domain Mg_chelatase PF01078.21 KXZ56004.1 - 6.5e-11 42.0 0.0 1.2e-05 24.8 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 KXZ56004.1 - 7.4e-05 21.9 0.1 0.025 13.7 0.0 2.6 2 1 0 2 2 2 2 MCM P-loop domain AAA_5 PF07728.14 KXZ56004.1 - 0.00032 20.7 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXZ56004.1 - 0.00038 20.2 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 KXZ56004.1 - 0.0016 18.8 2.0 0.003 18.0 0.1 2.5 2 2 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KXZ56004.1 - 0.0065 15.7 0.0 0.017 14.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXZ56004.1 - 0.0073 16.6 0.0 0.054 13.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXZ56004.1 - 0.0075 16.7 0.0 0.1 13.0 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXZ56004.1 - 0.018 14.5 0.0 0.051 13.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KXZ56004.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KXZ56004.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family CPP1-like PF11833.8 KXZ56005.1 - 2.4e-18 66.5 1.3 1.3e-17 64.1 1.3 1.9 1 1 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AAA_2 PF07724.14 KXZ56006.1 - 3.1e-40 138.1 0.0 3.5e-31 108.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 KXZ56006.1 - 6.3e-14 52.5 0.0 9.5e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ56006.1 - 1.6e-07 31.4 0.1 3.9e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXZ56006.1 - 1e-06 29.1 0.0 1.1e-05 25.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXZ56006.1 - 8.6e-06 26.2 1.9 8.6e-06 26.2 1.9 2.7 2 2 0 2 2 2 1 AAA ATPase domain ClpB_D2-small PF10431.9 KXZ56006.1 - 2.8e-05 24.1 2.3 8e-05 22.6 0.2 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_28 PF13521.6 KXZ56006.1 - 0.0001 22.6 3.0 0.00016 22.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 KXZ56006.1 - 0.00013 21.2 0.0 0.0052 15.9 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain AAA_18 PF13238.6 KXZ56006.1 - 0.00015 22.3 0.0 0.00036 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXZ56006.1 - 0.00044 20.3 0.0 0.5 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KXZ56006.1 - 0.00047 19.6 0.0 0.0046 16.4 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KXZ56006.1 - 0.00058 19.6 0.2 0.009 15.8 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KXZ56006.1 - 0.0017 18.9 0.0 0.0036 17.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 KXZ56006.1 - 0.0036 16.6 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 KXZ56006.1 - 0.0053 16.5 0.0 0.067 12.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KXZ56006.1 - 0.006 16.0 0.0 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 KXZ56006.1 - 0.0069 16.6 0.1 0.025 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KXZ56006.1 - 0.016 14.9 0.0 0.21 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KXZ56006.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 KXZ56006.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 KXZ56006.1 - 0.026 14.4 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.13 KXZ56006.1 - 0.027 13.7 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain SKI PF01202.22 KXZ56006.1 - 0.035 14.2 0.2 0.71 10.0 0.1 2.8 2 1 0 2 2 2 0 Shikimate kinase Rad17 PF03215.15 KXZ56006.1 - 0.039 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KXZ56006.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXZ56006.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KXZ56006.1 - 0.069 13.1 0.1 0.55 10.1 0.0 2.5 3 0 0 3 3 3 0 NACHT domain NTPase_1 PF03266.15 KXZ56006.1 - 0.084 12.8 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 KXZ56006.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KXZ56006.1 - 0.13 12.6 0.4 0.33 11.3 0.1 2.1 2 1 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KXZ56006.1 - 0.18 11.7 0.0 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KXZ56006.1 - 0.18 12.2 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CAF1 PF04857.20 KXZ56007.1 - 0.17 11.0 3.3 0.25 10.5 3.3 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease DDHD PF02862.17 KXZ56007.1 - 0.21 11.7 9.1 0.38 10.9 9.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF4471 PF14740.6 KXZ56007.1 - 0.22 10.7 3.2 0.35 10.0 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) GramPos_pilinD1 PF16555.5 KXZ56007.1 - 1.3 9.2 7.7 2.6 8.2 7.7 1.5 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain DUF5427 PF10310.9 KXZ56007.1 - 1.4 7.8 20.8 2.6 6.9 20.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Sec62 PF03839.16 KXZ56007.1 - 2.7 7.4 5.0 4.9 6.6 5.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 EIIBC-GUT_N PF03612.14 KXZ56007.1 - 3 7.6 10.4 6.1 6.5 10.4 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus MAT1 PF06391.13 KXZ56007.1 - 4.8 7.0 18.1 0.15 11.9 11.2 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4776 PF16003.5 KXZ56007.1 - 5.3 5.9 15.8 8 5.3 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Pneumo_att_G PF05539.11 KXZ56007.1 - 6.7 6.2 15.2 12 5.3 15.2 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Presenilin PF01080.17 KXZ56007.1 - 7.8 5.1 18.7 14 4.3 18.7 1.3 1 0 0 1 1 1 0 Presenilin Myosin_tail_1 PF01576.19 KXZ56008.1 - 0.02 12.7 9.7 0.028 12.3 9.3 1.4 1 1 0 1 1 1 0 Myosin tail TipAS PF07739.13 KXZ56008.1 - 0.095 13.3 4.1 0.18 12.3 3.0 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain YabA PF06156.13 KXZ56008.1 - 0.13 12.9 4.6 0.23 12.1 0.1 2.9 2 1 1 3 3 3 0 Initiation control protein YabA Fungal_TACC PF12709.7 KXZ56008.1 - 0.14 12.6 2.6 0.28 11.7 0.3 2.5 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 KXZ56008.1 - 0.25 11.7 4.3 11 6.5 0.0 3.4 4 0 0 4 4 4 0 TSC-22/dip/bun family CREPT PF16566.5 KXZ56008.1 - 0.79 9.9 11.5 1.6 8.9 0.1 2.9 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour TMF_DNA_bd PF12329.8 KXZ56008.1 - 2.3 8.3 12.2 21 5.2 0.5 4.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DnaJ_C PF01556.18 KXZ56009.1 - 5e-36 124.0 0.0 6.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXZ56009.1 - 4e-21 74.9 0.2 7e-21 74.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DENN PF02141.21 KXZ56010.1 - 7e-35 120.7 0.1 1.5e-34 119.6 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KXZ56010.1 - 2.6e-05 24.1 0.2 5.8e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 KXZ56010.1 - 5.8e-05 23.8 0.8 0.00019 22.1 0.2 2.2 2 0 0 2 2 2 1 uDENN domain PPR_2 PF13041.6 KXZ56011.1 - 3.9e-84 276.7 21.5 1.7e-14 53.7 0.1 8.5 2 1 7 9 9 9 8 PPR repeat family PPR PF01535.20 KXZ56011.1 - 3.4e-62 202.5 10.8 2.2e-07 30.7 0.0 9.8 10 0 0 10 10 9 8 PPR repeat PPR_3 PF13812.6 KXZ56011.1 - 3.1e-58 193.7 4.6 9e-15 54.5 1.1 6.2 3 3 2 6 6 6 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXZ56011.1 - 2.7e-55 183.7 6.1 2.8e-09 36.5 0.1 9.9 10 0 0 10 10 10 8 PPR repeat PPR_long PF17177.4 KXZ56011.1 - 1.9e-32 112.3 0.3 2e-15 56.7 0.1 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KXZ56011.1 - 9.3e-13 47.8 3.0 1.1 10.3 0.0 9.4 4 2 5 9 9 9 1 Tetratricopeptide repeat Cyclin_N PF00134.23 KXZ56011.1 - 7e-10 38.7 0.1 2.2e-09 37.1 0.0 2.0 2 0 0 2 2 1 1 Cyclin, N-terminal domain TPR_7 PF13176.6 KXZ56011.1 - 7.2e-08 31.9 5.8 3.5 7.9 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ56011.1 - 8e-07 29.5 2.7 3.5 8.2 0.0 5.7 3 2 4 7 7 7 2 Tetratricopeptide repeat Clathrin PF00637.20 KXZ56011.1 - 1.1e-05 25.4 0.3 0.26 11.2 0.0 4.1 3 2 2 5 5 5 2 Region in Clathrin and VPS Cyclin_C PF02984.19 KXZ56011.1 - 0.00011 22.2 0.1 0.00033 20.7 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain TPR_2 PF07719.17 KXZ56011.1 - 0.00012 21.9 5.4 14 6.1 0.1 7.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ56011.1 - 0.00016 21.8 6.0 22 5.4 0.0 6.5 4 2 0 5 5 5 0 Tetratricopeptide repeat PYRIN PF02758.16 KXZ56011.1 - 0.00034 20.7 1.8 21 5.3 0.0 5.2 4 1 1 5 5 5 0 PAAD/DAPIN/Pyrin domain BTAD PF03704.17 KXZ56011.1 - 0.0006 20.3 9.9 9.1 6.7 0.0 6.3 6 1 0 7 7 7 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 KXZ56011.1 - 0.0018 18.0 3.9 10 6.1 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ56011.1 - 0.0035 17.5 1.7 6.8 7.0 0.2 4.6 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXZ56011.1 - 0.0047 17.6 0.3 40 5.0 0.3 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat ECSIT PF06239.11 KXZ56011.1 - 0.0071 15.5 0.1 15 4.6 0.0 4.3 2 2 3 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_6 PF13174.6 KXZ56011.1 - 0.013 16.0 11.8 16 6.4 0.0 8.1 9 1 1 10 10 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ56011.1 - 0.036 14.0 0.1 62 3.7 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat RPM2 PF08579.11 KXZ56011.1 - 0.053 13.9 0.2 24 5.3 0.1 4.1 1 1 2 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) ChAPs PF09295.10 KXZ56011.1 - 0.074 12.0 0.1 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Cys_rich_FGFR PF00839.17 KXZ56012.1 - 4.5e-102 334.2 74.1 2.5e-12 46.8 0.2 12.2 12 0 0 12 12 12 12 Cysteine rich repeat DUF4045 PF13254.6 KXZ56012.1 - 1.6 8.3 17.0 2.5 7.6 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.12 KXZ56012.1 - 2.6 7.8 14.6 5.1 6.8 14.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.6 KXZ56012.1 - 7.1 6.5 19.4 14 5.6 19.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO LRR_4 PF12799.7 KXZ56013.1 - 1.1e-16 60.7 9.1 4.8e-05 23.6 0.2 5.3 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ56013.1 - 7.5e-10 38.4 15.8 0.013 15.3 1.5 5.2 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 KXZ56013.1 - 0.16 12.7 20.1 5.2 8.0 0.1 7.3 8 1 0 8 8 8 0 Leucine Rich Repeat Ribul_P_3_epim PF00834.19 KXZ56014.1 - 3.9e-86 287.5 0.4 4.6e-86 287.3 0.4 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family NanE PF04131.14 KXZ56014.1 - 0.00011 21.4 0.1 0.00025 20.3 0.1 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase PEP_mutase PF13714.6 KXZ56014.1 - 0.0058 16.1 0.2 1.3 8.4 0.1 2.5 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase PcrB PF01884.17 KXZ56014.1 - 0.016 14.7 2.5 0.87 9.0 0.3 2.2 1 1 1 2 2 2 0 PcrB family His_biosynth PF00977.21 KXZ56014.1 - 0.055 12.9 0.1 0.13 11.7 0.1 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein TMP-TENI PF02581.17 KXZ56014.1 - 0.21 10.9 2.0 0.25 10.7 0.1 2.1 3 0 0 3 3 3 0 Thiamine monophosphate synthase Pkinase PF00069.25 KXZ56015.1 - 2.1e-68 230.6 0.0 2.6e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56015.1 - 6.7e-27 94.4 0.0 8.5e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ56015.1 - 0.00012 21.5 0.0 0.024 14.0 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Choline_kinase PF01633.20 KXZ56015.1 - 0.0011 18.6 0.4 0.0017 18.0 0.4 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KXZ56015.1 - 0.0018 17.7 0.4 0.0027 17.1 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ56015.1 - 0.0038 17.2 0.0 0.012 15.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXZ56015.1 - 0.005 16.5 0.1 0.0088 15.7 0.1 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXZ56015.1 - 0.048 12.4 0.0 0.55 9.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase polyprenyl_synt PF00348.17 KXZ56018.1 - 3.3e-49 167.3 0.4 3.4e-47 160.6 0.4 2.1 1 1 0 1 1 1 1 Polyprenyl synthetase DnaJ PF00226.31 KXZ56019.1 - 0.002 18.2 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain PCIF1_WW PF12237.8 KXZ56019.1 - 0.087 12.4 0.0 11 5.6 0.0 2.5 3 0 0 3 3 3 0 Phosphorylated CTD interacting factor 1 WW domain Endonuc_Holl PF10107.9 KXZ56019.1 - 0.37 10.6 2.2 0.68 9.8 2.2 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Tim44 PF04280.15 KXZ56020.1 - 6.4e-06 26.3 0.2 1.3e-05 25.3 0.0 1.5 2 0 0 2 2 2 1 Tim44-like domain NAD_Gly3P_dh_C PF07479.14 KXZ56021.1 - 5.3e-47 159.7 0.5 1e-46 158.7 0.5 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KXZ56021.1 - 3.3e-41 140.9 0.0 6.4e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KXZ56021.1 - 3e-05 23.7 0.0 5.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KXZ56021.1 - 0.067 13.8 0.1 0.44 11.1 0.0 2.5 2 2 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ndufs5 PF10200.9 KXZ56022.1 - 2.2e-05 24.6 0.3 2.7e-05 24.3 0.3 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UCR_hinge PF02320.16 KXZ56022.1 - 4.2e-05 23.6 3.1 0.1 12.8 0.1 2.1 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.17 KXZ56022.1 - 0.00026 21.2 7.0 0.033 14.4 0.7 2.0 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb DUF3134 PF11332.8 KXZ56022.1 - 0.004 17.4 0.1 0.0053 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3134) COX17 PF05051.13 KXZ56022.1 - 0.0046 17.3 1.3 0.85 10.0 0.1 2.2 2 0 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) rve_3 PF13683.6 KXZ56022.1 - 0.0049 16.6 0.2 0.0095 15.7 0.1 1.5 1 1 0 1 1 1 1 Integrase core domain Mac PF12464.8 KXZ56022.1 - 0.0057 16.9 4.0 0.0089 16.3 4.1 1.4 1 1 0 1 1 1 1 Maltose acetyltransferase UPF0203 PF05254.12 KXZ56022.1 - 0.0081 16.4 5.5 0.012 15.9 5.5 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) MFS_1 PF07690.16 KXZ56025.1 - 1.2e-14 54.0 36.8 1.2e-14 54.0 36.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXZ56025.1 - 1.3e-06 27.6 3.6 1.3e-06 27.6 3.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3638 PF12340.8 KXZ56026.1 - 3e-56 190.3 0.0 4.9e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXZ56026.1 - 4.3e-13 48.4 0.2 9.3e-13 47.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF3584 PF12128.8 KXZ56027.1 - 0.1 10.1 5.7 0.16 9.5 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 KXZ56027.1 - 6 7.4 5.5 25 5.4 2.1 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region FSA_C PF10479.9 KXZ56028.1 - 3.9 5.5 6.9 8.2 4.4 6.6 1.6 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus DNA_pol_A_exo1 PF01612.20 KXZ56029.1 - 2.1e-37 128.5 0.0 3.1e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 KXZ56029.1 - 1.2e-08 34.9 0.0 2.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 HRDC domain B9-C2 PF07162.11 KXZ56030.1 - 3.6e-18 66.3 0.0 3.9e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Guanylate_cyc PF00211.20 KXZ56031.1 - 1.4e-05 24.8 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SBP_bac_1 PF01547.25 KXZ56031.1 - 0.0016 18.5 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KXZ56031.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Fer4_5 PF12801.7 KXZ56033.1 - 7.6e-12 45.0 22.6 4.5e-07 29.7 1.4 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Sigma54_activat PF00158.26 KXZ56033.1 - 1.3e-10 41.2 0.0 3.1e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KXZ56033.1 - 7e-09 35.9 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Fer4 PF00037.27 KXZ56033.1 - 0.0035 17.1 2.0 0.012 15.4 2.0 1.9 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_10 PF13237.6 KXZ56033.1 - 0.018 15.2 0.2 0.018 15.2 0.2 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXZ56033.1 - 0.02 14.9 3.3 0.02 14.9 3.3 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain RuvB_N PF05496.12 KXZ56033.1 - 0.021 14.6 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Fer4_2 PF12797.7 KXZ56033.1 - 0.076 13.1 3.7 0.34 11.1 3.7 2.1 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_9 PF13187.6 KXZ56033.1 - 0.097 12.9 9.1 0.46 10.7 9.1 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KXZ56033.1 - 0.18 12.4 7.8 0.46 11.1 7.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KXZ56033.1 - 0.51 11.0 6.1 0.12 12.9 2.0 2.1 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_21 PF14697.6 KXZ56033.1 - 0.56 10.4 3.1 0.35 11.1 0.8 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXZ56033.1 - 3.2 8.4 9.7 0.38 11.4 3.7 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXZ56033.1 - 3.9 8.0 8.4 6.5 7.3 7.3 1.9 2 0 0 2 2 1 0 4Fe-4S dicluster domain TFA2_Winged_2 PF18121.1 KXZ56034.1 - 2.7e-09 36.6 0.0 6.1e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KXZ56034.1 - 3.8e-05 23.9 0.2 0.00013 22.1 0.1 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain HTH_11 PF08279.12 KXZ56034.1 - 0.07 13.1 0.0 8.7 6.4 0.0 2.8 3 0 0 3 3 3 0 HTH domain Swi3 PF07962.12 KXZ56035.1 - 2.5e-08 33.8 0.1 4e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 WD40 PF00400.32 KXZ56037.1 - 5.2e-102 330.9 24.0 4.2e-09 36.9 0.2 13.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56037.1 - 1.2e-33 115.2 0.6 0.0005 20.3 0.0 10.8 2 2 8 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ56037.1 - 1.2e-16 60.6 5.7 1.3 7.9 0.0 9.8 2 2 8 10 10 10 7 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KXZ56037.1 - 1.6e-06 28.6 0.1 5.2e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXZ56037.1 - 5.1e-05 23.3 0.4 0.011 15.6 0.3 2.4 2 0 0 2 2 2 1 NACHT domain Frtz PF11768.8 KXZ56037.1 - 0.00012 20.5 0.0 0.36 9.1 0.0 3.4 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KXZ56037.1 - 0.0056 16.1 5.5 12 5.2 0.0 5.8 3 2 4 7 7 7 1 Neuroblastoma-amplified sequence, N terminal AAA_30 PF13604.6 KXZ56037.1 - 0.028 14.1 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXZ56037.1 - 0.097 12.4 0.0 0.34 10.7 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain PD40 PF07676.12 KXZ56037.1 - 0.15 12.0 0.0 8.1 6.5 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat AAA_23 PF13476.6 KXZ56037.1 - 0.22 12.0 0.0 0.45 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXZ56037.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DHQ_synthase PF01761.20 KXZ56038.1 - 1.7e-98 329.0 0.0 2e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KXZ56038.1 - 9.9e-11 41.8 0.0 8.2e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KXZ56038.1 - 1.6e-06 27.2 0.0 4.7e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase UPF0061 PF02696.14 KXZ56039.1 - 1.7e-63 215.1 0.0 2.7e-63 214.4 0.0 1.2 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family ATP_transf PF09830.9 KXZ56040.1 - 1.5e-19 69.9 0.0 3.2e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase CAP_N PF01213.19 KXZ56040.1 - 4 6.8 11.5 7.1 6.0 11.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 KXZ56042.1 - 1.8e-38 132.5 0.0 3e-38 131.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56042.1 - 2.2e-18 66.5 0.0 3.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ56042.1 - 0.0037 17.2 0.4 0.01 15.7 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L18 PF17135.4 KXZ56044.1 - 2.3e-94 314.0 2.7 2.6e-94 313.9 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KXZ56044.1 - 5.2e-05 23.9 0.2 0.00041 21.0 0.2 2.2 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Trm112p PF03966.16 KXZ56045.1 - 4.3e-09 36.8 0.0 5.1e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Pkinase_Tyr PF07714.17 KXZ56046.1 - 1.1e-40 139.6 0.0 2.6e-40 138.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ56046.1 - 1.7e-38 132.5 0.0 2.4e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ56046.1 - 0.00018 20.4 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH_6_hur PF04655.14 KXZ56046.1 - 0.0059 16.0 0.6 0.07 12.5 0.2 2.3 2 0 0 2 2 2 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.23 KXZ56046.1 - 0.027 14.4 0.1 0.027 14.4 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cupin_8 PF13621.6 KXZ56047.1 - 2.6e-18 66.6 0.0 2.3e-17 63.6 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXZ56047.1 - 1.1e-09 38.8 0.0 1.6e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 KXZ56047.1 - 0.00078 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DUF1279 PF06916.13 KXZ56048.1 - 1.9e-20 73.2 0.1 3.2e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3995 PF13160.6 KXZ56048.1 - 0.047 14.1 4.9 0.16 12.3 4.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Peptidase_M41 PF01434.18 KXZ56049.1 - 1.1e-68 230.8 0.0 1.8e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXZ56049.1 - 2.8e-45 154.0 0.0 8.4e-45 152.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ56049.1 - 1.4e-16 60.0 1.2 3e-16 58.9 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KXZ56049.1 - 0.00011 22.3 0.1 0.0015 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.15 KXZ56049.1 - 0.00023 21.5 0.0 0.0039 17.5 0.0 2.5 2 0 0 2 2 2 1 FtsH Extracellular AAA_2 PF07724.14 KXZ56049.1 - 0.0012 19.0 0.0 0.0044 17.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KXZ56049.1 - 0.0026 17.0 0.2 0.0052 16.0 0.2 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXZ56049.1 - 0.0028 17.9 0.1 0.055 13.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXZ56049.1 - 0.0036 17.1 0.0 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXZ56049.1 - 0.0096 16.3 5.4 0.041 14.3 0.1 3.6 3 1 1 4 4 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KXZ56049.1 - 0.024 14.3 0.3 0.065 13.0 0.1 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXZ56049.1 - 0.035 13.5 0.2 0.07 12.5 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXZ56049.1 - 0.041 14.1 0.1 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXZ56049.1 - 0.044 13.9 0.6 0.1 12.8 0.2 2.0 2 1 0 2 2 1 0 AAA domain Apocytochr_F_N PF16639.5 KXZ56049.1 - 0.083 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Apocytochrome F, N-terminal AAA_25 PF13481.6 KXZ56049.1 - 0.088 12.4 1.4 1.2 8.6 0.5 2.6 1 1 0 2 2 2 0 AAA domain FAD-SLDH PF12318.8 KXZ56049.1 - 0.12 12.5 1.1 5 7.2 0.0 2.9 3 0 0 3 3 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_17 PF13207.6 KXZ56049.1 - 0.12 12.8 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain GAIN_A PF18619.1 KXZ56049.1 - 0.13 12.5 0.2 6.7 7.0 0.3 2.6 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A AAA_7 PF12775.7 KXZ56049.1 - 0.25 10.9 0.2 0.72 9.3 0.2 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KXZ56049.1 - 0.27 11.8 0.7 0.71 10.4 0.0 2.1 3 0 0 3 3 1 0 AAA domain Amino_oxidase PF01593.24 KXZ56050.1 - 6.2e-56 190.6 0.0 7.2e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXZ56050.1 - 3.9e-14 52.6 0.2 1.1e-13 51.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXZ56050.1 - 3.2e-05 23.7 1.5 0.00016 21.4 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ56050.1 - 0.00026 20.3 0.2 0.00088 18.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXZ56050.1 - 0.00035 20.1 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXZ56050.1 - 0.00043 19.5 1.0 0.0011 18.2 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain MCRA PF06100.11 KXZ56050.1 - 0.00063 18.7 0.0 0.58 8.9 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_binding_3 PF01494.19 KXZ56050.1 - 0.00092 18.5 0.3 0.0014 17.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXZ56050.1 - 0.0014 17.4 0.1 0.0027 16.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXZ56050.1 - 0.024 15.2 0.1 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXZ56050.1 - 0.037 13.3 0.6 0.2 10.9 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXZ56050.1 - 0.084 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXZ56050.1 - 0.14 12.2 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding WW PF00397.26 KXZ56051.1 - 3.3e-11 43.0 1.1 6.4e-11 42.1 1.1 1.5 1 0 0 1 1 1 1 WW domain zf-CCHC PF00098.23 KXZ56051.1 - 8.4e-05 22.5 1.8 0.00012 21.9 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXZ56051.1 - 0.011 15.5 0.4 0.017 14.8 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle APOC4 PF15119.6 KXZ56051.1 - 0.072 13.4 0.2 0.17 12.2 0.2 1.8 1 1 0 1 1 1 0 Apolipoprotein C4 SUZ PF12752.7 KXZ56051.1 - 0.073 13.8 0.0 0.14 12.9 0.1 1.6 2 0 0 2 2 2 0 SUZ domain CLP_protease PF00574.23 KXZ56052.1 - 1.1e-78 263.3 0.1 1.4e-78 263.0 0.1 1.1 1 0 0 1 1 1 1 Clp protease DUF3445 PF11927.8 KXZ56054.1 - 2.7e-55 187.5 0.0 3.5e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MBOAT PF03062.19 KXZ56055.1 - 1.3e-32 113.5 3.7 2.5e-32 112.6 3.6 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SLATT_4 PF18186.1 KXZ56056.1 - 0.011 15.4 0.5 0.011 15.4 0.5 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 SNF2_N PF00176.23 KXZ56057.1 - 2.4e-22 79.1 0.0 6.2e-22 77.8 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KXZ56057.1 - 3e-11 43.0 1.5 0.0002 21.2 0.0 3.1 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 KXZ56057.1 - 5.1e-10 39.6 0.1 2.1e-08 34.5 0.3 3.0 3 0 0 3 3 3 1 PWWP domain DUF3445 PF11927.8 KXZ56058.1 - 5e-29 101.5 0.0 8e-21 74.7 0.0 3.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3445) Ferric_reduct PF01794.19 KXZ56058.1 - 6.1e-17 61.9 8.6 6.1e-17 61.9 8.6 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXZ56058.1 - 1.7e-10 40.9 0.0 3.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXZ56058.1 - 1.8e-07 31.4 0.0 4.8e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Transket_pyr PF02779.24 KXZ56059.1 - 4.2e-69 231.8 0.0 6.8e-69 231.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KXZ56059.1 - 1e-66 224.9 0.1 1.5e-66 224.4 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KXZ56059.1 - 1.1e-46 158.3 0.0 2.1e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KXZ56059.1 - 4.2e-14 51.9 0.1 1.1e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Ribonuc_P_40 PF08584.11 KXZ56059.1 - 0.11 11.8 0.1 8.3 5.6 0.0 2.2 1 1 1 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit 2-oxogl_dehyd_N PF16078.5 KXZ56060.1 - 1.9e-12 46.5 0.1 2.9e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus DUF3552 PF12072.8 KXZ56061.1 - 0.0019 17.7 19.0 0.003 17.0 19.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) FliJ PF02050.16 KXZ56061.1 - 0.0049 17.1 9.8 0.27 11.5 3.0 2.3 1 1 1 2 2 2 2 Flagellar FliJ protein ATP-synt_D PF01813.17 KXZ56061.1 - 0.0086 15.9 3.0 0.0086 15.9 3.0 1.7 2 0 0 2 2 2 1 ATP synthase subunit D OmpH PF03938.14 KXZ56061.1 - 0.18 12.1 13.4 3.2 8.1 8.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FlxA PF14282.6 KXZ56061.1 - 1.6 8.7 10.5 0.38 10.8 6.5 1.9 1 1 1 2 2 2 0 FlxA-like protein Cob_adeno_trans PF01923.18 KXZ56061.1 - 2.5 8.2 5.1 11 6.1 1.2 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spc7 PF08317.11 KXZ56061.1 - 7.3 5.4 18.1 5 5.9 12.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 KXZ56061.1 - 8.6 6.4 25.8 3.1 7.8 0.7 3.2 2 1 0 3 3 3 0 Prefoldin subunit TPP_enzyme_N PF02776.18 KXZ56062.1 - 3.1e-19 69.2 0.1 3.9e-19 68.9 0.1 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain OxoGdeHyase_C PF16870.5 KXZ56063.1 - 1.3e-37 128.9 0.0 1.6e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 KXZ56064.1 - 1.2e-66 223.8 0.0 2.3e-66 222.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KXZ56064.1 - 1.4e-46 157.9 0.0 2.6e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KXZ56064.1 - 9.9e-28 96.9 0.0 3.7e-15 55.6 0.0 2.2 1 1 1 2 2 2 2 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KXZ56064.1 - 1.2e-11 44.0 0.1 2.5e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus dDENN PF03455.19 KXZ56064.1 - 0.019 15.0 0.0 4.2 7.5 0.1 2.9 2 0 0 2 2 2 0 dDENN domain Sel1 PF08238.12 KXZ56069.1 - 0.00038 21.0 2.1 0.00076 20.1 2.1 1.5 1 0 0 1 1 1 1 Sel1 repeat WD40 PF00400.32 KXZ56070.1 - 1.2e-12 48.1 8.1 0.013 16.3 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56070.1 - 8.5e-09 35.6 0.9 0.68 10.3 0.0 5.9 4 3 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KXZ56070.1 - 0.37 10.8 1.7 31 4.7 0.1 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat DUF1263 PF06882.12 KXZ56071.1 - 0.052 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) WD40 PF00400.32 KXZ56072.1 - 0.083 13.8 1.8 5 8.2 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat PIH1_CS PF18201.1 KXZ56073.1 - 1.3e-06 28.8 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain TPP_enzyme_N PF02776.18 KXZ56074.1 - 6.2e-17 61.7 0.3 6.7e-17 61.6 0.3 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Pkinase PF00069.25 KXZ56075.1 - 2.2e-07 30.5 0.0 1.2e-06 28.2 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56075.1 - 0.053 12.8 0.0 0.17 11.1 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ56075.1 - 0.069 11.9 0.1 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase CCDC-167 PF15188.6 KXZ56075.1 - 0.72 10.2 10.5 1.6 9.1 10.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Gp_dh_C PF02800.20 KXZ56078.1 - 3.8e-37 127.3 0.0 1.4e-36 125.5 0.0 1.8 1 1 1 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXZ56078.1 - 4.8e-25 87.8 0.0 9.4e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PGK PF00162.19 KXZ56079.1 - 2.2e-77 260.6 0.0 2.6e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PGK PF00162.19 KXZ56080.1 - 7.6e-38 130.4 0.0 9.2e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase MFS_1 PF07690.16 KXZ56081.1 - 3.8e-06 26.1 42.2 0.021 13.8 29.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3593 PF12159.8 KXZ56084.1 - 1.7e-36 124.1 1.5 1.7e-36 124.1 1.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3593) PhoLip_ATPase_C PF16212.5 KXZ56084.1 - 1e-24 87.7 5.8 1e-24 87.7 5.8 1.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KXZ56084.1 - 9.2e-12 44.9 0.1 4.1e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXZ56084.1 - 1.7e-09 38.3 0.6 1.1e-05 25.8 0.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXZ56084.1 - 0.052 13.3 0.1 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 KXZ56084.1 - 0.15 11.4 1.1 0.26 10.7 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) mRNA_cap_enzyme PF01331.19 KXZ56085.1 - 1.2e-41 142.7 0.0 2.3e-28 99.4 0.0 2.2 1 1 1 2 2 2 2 mRNA capping enzyme, catalytic domain H2TH PF06831.14 KXZ56085.1 - 8.8e-24 83.3 0.0 2e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain SAP PF02037.27 KXZ56085.1 - 2e-13 49.7 10.8 4.6e-08 32.6 2.1 2.5 2 0 0 2 2 2 2 SAP domain mRNA_cap_C PF03919.15 KXZ56085.1 - 5.9e-13 49.4 0.0 1.2e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 KXZ56085.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Fapy_DNA_glyco PF01149.24 KXZ56085.1 - 0.013 16.1 0.0 0.037 14.7 0.0 1.7 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase N-terminal domain Y_phosphatase PF00102.27 KXZ56085.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXZ56085.1 - 0.12 12.4 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family ASF1_hist_chap PF04729.13 KXZ56087.1 - 1.1e-62 210.5 0.1 1.3e-62 210.3 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone TPR_19 PF14559.6 KXZ56089.1 - 1.8e-05 25.1 2.8 1.8e-05 25.1 2.8 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ56089.1 - 0.0028 17.4 0.1 0.0028 17.4 0.1 5.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ56089.1 - 0.0036 17.6 2.8 0.0036 17.6 2.8 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ56089.1 - 0.0036 17.1 3.0 0.0036 17.1 3.0 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ56089.1 - 0.0048 17.6 1.4 0.0048 17.6 1.4 10.6 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ56089.1 - 0.01 15.8 0.0 0.01 15.8 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ56089.1 - 0.019 15.0 0.3 0.019 15.0 0.3 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ56089.1 - 0.048 13.9 0.6 3.1 8.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HisKA PF00512.25 KXZ56089.1 - 0.38 10.8 2.2 1.5 8.9 0.1 2.9 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Diphthamide_syn PF01866.17 KXZ56090.1 - 2.8e-34 119.0 0.0 3.5e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Inositol_P PF00459.25 KXZ56091.1 - 1.8e-49 168.7 0.1 2.2e-49 168.4 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 KXZ56091.1 - 0.0074 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain EMP70 PF02990.16 KXZ56091.1 - 0.038 12.6 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Rab5ip PF07019.12 KXZ56092.1 - 2.2e-16 60.2 6.3 2.9e-16 59.8 6.3 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) eIF2A PF08662.11 KXZ56093.1 - 7.2e-31 107.6 0.0 9.4e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A SnoaL_3 PF13474.6 KXZ56093.1 - 1.5e-23 83.3 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXZ56093.1 - 1.4e-07 31.9 0.1 2.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KXZ56093.1 - 2.2e-05 25.0 0.8 4.5e-05 24.0 0.8 1.5 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 KXZ56093.1 - 0.012 15.8 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain DUF2905 PF11146.8 KXZ56093.1 - 0.05 13.8 0.1 0.17 12.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) VID27 PF08553.10 KXZ56093.1 - 0.11 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Pkinase_Tyr PF07714.17 KXZ56095.1 - 9.9e-12 44.7 0.0 1.5e-07 31.0 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ56095.1 - 5e-10 39.2 0.0 1.5e-07 31.1 0.0 2.8 2 1 0 3 3 3 2 Protein kinase domain X PF00739.19 KXZ56095.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Trans-activation protein X CENP-F_leu_zip PF10473.9 KXZ56096.1 - 0.64 10.0 35.5 0.42 10.6 8.3 4.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps54_N PF10475.9 KXZ56096.1 - 2 7.6 4.9 1.2 8.4 1.0 2.3 2 1 1 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex ATG16 PF08614.11 KXZ56096.1 - 4.1 7.6 77.9 0.12 12.6 20.7 4.7 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Lectin_N PF03954.14 KXZ56096.1 - 6.3 6.5 10.0 7.4 6.3 0.2 3.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain TPR_2 PF07719.17 KXZ56097.1 - 0.00061 19.7 3.1 0.0032 17.5 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ56097.1 - 0.00077 19.2 0.3 0.0063 16.3 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ56097.1 - 0.015 15.5 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Abhydrolase_1 PF00561.20 KXZ56098.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_11 PF08241.12 KXZ56099.1 - 8.4e-05 23.1 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ56099.1 - 0.00015 22.4 0.0 0.0004 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SIS PF01380.22 KXZ56100.1 - 7.9e-45 151.9 1.5 1.1e-29 102.9 0.1 3.2 3 0 0 3 3 3 3 SIS domain GATase_6 PF13522.6 KXZ56100.1 - 4.7e-15 56.0 0.0 1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXZ56100.1 - 4.5e-10 39.5 0.0 9.3e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXZ56100.1 - 5.9e-05 22.1 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF2529 PF10740.9 KXZ56100.1 - 0.03 14.0 0.0 0.94 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) SIS_2 PF13580.6 KXZ56100.1 - 0.13 12.3 0.0 8.1 6.5 0.0 2.9 3 0 0 3 3 3 0 SIS domain PWI PF01480.17 KXZ56101.1 - 1.1e-12 48.1 0.0 2.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KXZ56101.1 - 5.4e-11 42.2 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPCR_chapero_1 PF11904.8 KXZ56104.1 - 8.1e-19 68.2 0.0 1.1e-18 67.8 0.0 1.3 1 1 0 1 1 1 1 GPCR-chaperone PI31_Prot_N PF11566.8 KXZ56104.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal Ribosomal_S19 PF00203.21 KXZ56106.1 - 1.9e-29 101.4 0.0 2.8e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SRR1 PF07985.12 KXZ56107.1 - 0.00058 19.8 0.5 0.91 9.6 0.4 2.6 2 0 0 2 2 2 2 SRR1 DUF4407 PF14362.6 KXZ56107.1 - 0.0022 17.4 1.6 0.0035 16.8 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Med15 PF09606.10 KXZ56107.1 - 0.0024 16.7 25.7 0.0024 16.7 25.7 1.7 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal CCDC53 PF10152.9 KXZ56107.1 - 0.016 15.6 1.7 0.029 14.8 1.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 KXZ56107.1 - 0.37 9.5 0.4 0.47 9.2 0.4 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 KXZ56107.1 - 0.51 11.0 13.9 0.58 10.8 13.0 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 KXZ56107.1 - 0.56 10.1 13.4 0.77 9.7 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HABP4_PAI-RBP1 PF04774.15 KXZ56107.1 - 1.1 10.1 5.4 2 9.3 5.4 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Kei1 PF08552.11 KXZ56107.1 - 1.7 8.5 4.2 2.6 7.9 4.2 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Spt20 PF12090.8 KXZ56107.1 - 8.7 5.9 17.6 12 5.4 17.6 1.1 1 0 0 1 1 1 0 Spt20 family adh_short PF00106.25 KXZ56108.1 - 2.9e-16 59.5 0.1 7.3e-08 32.1 2.2 3.1 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ56108.1 - 1.4e-09 37.8 0.1 0.0011 18.5 1.7 2.8 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ56108.1 - 3.2e-05 23.9 0.1 0.00018 21.5 0.1 2.0 1 1 0 1 1 1 1 KR domain YjeF_N PF03853.15 KXZ56108.1 - 0.014 15.3 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus PRIMA1 PF16101.5 KXZ56108.1 - 1.5 8.9 5.5 5.7 7.0 2.3 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 adh_short PF00106.25 KXZ56109.1 - 1.7e-15 57.0 0.0 2.5e-08 33.6 0.5 3.4 3 0 0 3 3 3 2 short chain dehydrogenase Homeobox_KN PF05920.11 KXZ56109.1 - 1e-13 50.9 1.0 2.6e-13 49.7 1.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain adh_short_C2 PF13561.6 KXZ56109.1 - 2e-08 34.1 0.0 0.00085 18.9 0.8 3.3 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ56109.1 - 1.9e-05 24.6 0.0 0.00018 21.5 0.0 2.3 2 0 0 2 2 2 1 KR domain Homeodomain PF00046.29 KXZ56109.1 - 0.00036 20.3 2.1 0.0022 17.8 0.4 2.5 2 0 0 2 2 2 1 Homeodomain KNOX2 PF03791.13 KXZ56109.1 - 0.0018 17.8 0.1 0.0037 16.7 0.1 1.5 1 0 0 1 1 1 1 KNOX2 domain Dscam_C PF12355.8 KXZ56109.1 - 0.7 10.9 4.0 2.5 9.1 3.3 2.2 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal DSPc PF00782.20 KXZ56110.1 - 1.9e-31 108.6 0.0 2.7e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Act-Frag_cataly PF09192.10 KXZ56110.1 - 3e-13 49.8 0.0 4.3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic Init_tRNA_PT PF04179.12 KXZ56110.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KXZ56110.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RVT_1 PF00078.27 KXZ56111.1 - 4.5e-37 127.7 0.0 6.4e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) A2M PF00207.22 KXZ56112.1 - 8e-08 32.0 0.0 2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Big_1 PF02369.16 KXZ56112.1 - 0.0025 17.8 15.0 0.15 12.1 0.9 4.3 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 1) MG4 PF17789.1 KXZ56112.1 - 0.027 14.6 0.1 1.9 8.7 0.0 3.6 4 0 0 4 4 4 0 Macroglobulin domain MG4 A2M_BRD PF07703.14 KXZ56112.1 - 0.15 12.5 0.4 0.72 10.2 0.2 2.4 2 0 0 2 2 2 0 Alpha-2-macroglobulin bait region domain TIC20 PF16166.5 KXZ56113.1 - 7.6e-24 84.5 7.6 8.4e-24 84.3 7.6 1.0 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like PGM_PMM_I PF02878.16 KXZ56114.1 - 2.6e-17 62.8 0.2 1.9e-07 30.8 0.1 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KXZ56114.1 - 6.4e-09 35.9 0.1 1.8e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KXZ56114.1 - 0.00088 19.5 0.0 0.002 18.3 0.0 1.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF1859 PF08948.10 KXZ56114.1 - 0.028 14.3 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) PGM_PMM_II PF02879.16 KXZ56114.1 - 0.034 14.8 1.2 0.71 10.5 0.6 3.5 2 2 1 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Transmemb_17 PF09799.9 KXZ56115.1 - 2.6e-30 105.1 10.7 3.7e-30 104.7 10.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein NicO PF03824.16 KXZ56115.1 - 0.054 12.8 5.7 0.027 13.8 3.8 1.4 1 1 0 1 1 1 0 High-affinity nickel-transport protein DNA_pol_phi PF04931.13 KXZ56116.1 - 3.1 5.8 3.7 4 5.4 3.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi FAST_1 PF06743.15 KXZ56119.1 - 0.016 15.2 0.3 2 8.4 0.1 2.8 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 TFIIA PF03153.13 KXZ56119.1 - 4.4 7.2 7.2 6.3 6.7 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAD_2 PF13419.6 KXZ56120.1 - 8.6e-27 94.4 0.0 1.1e-26 94.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ56120.1 - 4.3e-15 56.6 0.7 2.3e-14 54.2 0.7 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ56120.1 - 2.3e-06 28.1 0.1 3.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ56120.1 - 0.00073 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 KXZ56120.1 - 0.042 13.6 0.0 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase GDI PF00996.18 KXZ56121.1 - 1.8e-18 66.3 0.0 4.6e-09 35.3 0.0 2.8 3 0 0 3 3 3 2 GDP dissociation inhibitor DUF3591 PF12157.8 KXZ56124.1 - 9.5e-58 195.9 0.0 1.5e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KXZ56124.1 - 5.1e-08 32.9 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.11 KXZ56124.1 - 1.5e-05 25.1 1.8 1.5e-05 25.1 1.8 2.2 1 1 1 2 2 2 1 TATA box-binding protein binding zf-CW PF07496.15 KXZ56124.1 - 0.0011 18.9 2.0 0.0025 17.8 2.0 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger Peptidase_S41 PF03572.18 KXZ56125.1 - 2.5e-11 43.4 0.0 5.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 KXZ56125.1 - 4.7e-08 32.8 0.1 1.4e-07 31.3 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXZ56125.1 - 5.5e-08 33.0 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KXZ56125.1 - 2.5e-05 24.6 0.1 5.3e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KXZ56125.1 - 0.00056 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain Pkinase PF00069.25 KXZ56126.1 - 5.2e-16 58.8 0.0 3.1e-10 39.9 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56126.1 - 1e-15 57.7 0.0 4.5e-11 42.5 0.0 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase Ank_3 PF13606.6 KXZ56128.1 - 0.0035 17.7 0.8 7.2 7.5 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat SBP PF03110.14 KXZ56128.1 - 0.008 16.5 0.1 0.028 14.7 0.2 1.9 2 0 0 2 2 2 1 SBP domain Ank_4 PF13637.6 KXZ56128.1 - 0.036 14.6 0.0 2.2 9.0 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KXZ56128.1 - 0.15 12.6 0.7 30 5.3 0.2 2.9 2 0 0 2 2 2 0 Ankyrin repeat MscS_TM PF12794.7 KXZ56129.1 - 0.11 11.3 3.2 0.13 11.1 3.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nup84_Nup100 PF04121.13 KXZ56131.1 - 3.6e-44 151.0 0.0 4.8e-42 144.0 0.0 2.4 3 0 0 3 3 3 2 Nuclear pore protein 84 / 107 REV1_C PF16727.5 KXZ56131.1 - 0.062 13.7 0.2 0.28 11.6 0.0 2.2 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain WD40 PF00400.32 KXZ56132.1 - 1.2e-05 25.9 0.2 0.72 10.8 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Nbas_N PF15492.6 KXZ56132.1 - 0.041 13.2 0.0 0.095 12.0 0.0 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RNase_T PF00929.24 KXZ56133.1 - 2.8e-34 119.1 0.1 3.4e-34 118.8 0.1 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KXZ56133.1 - 2.2e-06 27.7 0.1 3.1e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like NAM-associated PF14303.6 KXZ56133.1 - 0.054 14.2 0.0 0.086 13.6 0.0 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Chloroa_b-bind PF00504.21 KXZ56134.1 - 1.3e-47 162.3 0.0 1.7e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Nucleoporin_FG2 PF15967.5 KXZ56134.1 - 0.2 10.2 0.1 0.26 9.8 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region WGG PF10273.9 KXZ56135.1 - 2.4e-22 79.4 0.5 2.4e-22 79.4 0.5 1.5 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 DUF4611 PF15387.6 KXZ56135.1 - 1.9e-06 28.0 0.8 3.2e-06 27.3 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) Cys_Met_Meta_PP PF01053.20 KXZ56136.1 - 9.2e-60 202.2 0.0 1.3e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXZ56136.1 - 1.8e-07 30.7 0.0 3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXZ56136.1 - 0.0032 16.5 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF5473 PF17567.2 KXZ56136.1 - 0.041 14.2 0.3 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5473) Met_gamma_lyase PF06838.11 KXZ56136.1 - 0.071 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase Asn_synthase PF00733.21 KXZ56138.1 - 1.2e-11 44.9 0.0 2.6e-11 43.8 0.0 1.3 1 1 0 1 1 1 1 Asparagine synthase zinc_ribbon_2 PF13240.6 KXZ56138.1 - 1.4e-05 24.6 3.6 3.2e-05 23.5 3.6 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KXZ56138.1 - 0.00022 21.2 0.1 0.00044 20.2 0.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KXZ56138.1 - 0.048 13.6 0.5 0.12 12.4 0.3 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 KXZ56138.1 - 0.087 12.3 3.9 0.21 11.0 3.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 KXZ56138.1 - 0.17 11.4 1.1 0.35 10.4 1.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger Prenylcys_lyase PF07156.14 KXZ56140.1 - 5.3e-54 183.7 0.0 1e-29 103.8 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase NDK PF00334.19 KXZ56141.1 - 2.1e-52 176.7 0.0 2.6e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NUDIX PF00293.28 KXZ56143.1 - 3.4e-22 78.9 0.0 8.5e-22 77.6 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain PEP-utilizers_C PF02896.18 KXZ56144.1 - 1.1e-93 313.5 0.1 1.6e-93 313.1 0.1 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 KXZ56144.1 - 3.4e-57 194.2 0.0 9.2e-43 146.8 0.0 3.1 1 1 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 KXZ56144.1 - 1.1e-26 92.3 1.7 2.9e-26 91.0 0.2 2.4 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain DDE_3 PF13358.6 KXZ56146.1 - 2.7e-27 95.3 0.0 3.7e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Defensin_propep PF00879.18 KXZ56147.1 - 0.013 15.7 0.4 0.025 14.8 0.4 1.6 1 0 0 1 1 1 0 Defensin propeptide CENP-F_leu_zip PF10473.9 KXZ56147.1 - 0.018 15.1 0.5 0.02 14.9 0.5 1.0 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin PF00804.25 KXZ56147.1 - 0.054 13.2 0.5 0.056 13.1 0.5 1.0 1 0 0 1 1 1 0 Syntaxin DUF5344 PF17279.2 KXZ56147.1 - 0.08 13.5 0.1 0.093 13.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5344) YdfA_immunity PF12127.8 KXZ56147.1 - 0.87 8.6 4.8 0.94 8.5 4.8 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial LRR_6 PF13516.6 KXZ56149.1 - 4.2e-17 60.7 21.2 0.00048 20.0 0.1 9.1 10 0 0 10 10 10 5 Leucine Rich repeat DUF4476 PF14771.6 KXZ56149.1 - 2.3e-13 50.3 0.0 3.8e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4476) LRR_1 PF00560.33 KXZ56149.1 - 0.43 11.3 12.6 21 6.2 0.0 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat Cyclin_C PF02984.19 KXZ56150.1 - 0.028 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain PAP_fibrillin PF04755.12 KXZ56152.1 - 0.0004 20.4 0.1 0.0004 20.4 0.1 3.3 3 1 0 3 3 3 1 PAP_fibrillin DUF4407 PF14362.6 KXZ56152.1 - 0.011 15.1 19.7 0.019 14.3 19.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coprogen_oxidas PF01218.18 KXZ56152.1 - 0.1 11.3 0.8 0.15 10.8 0.8 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase Noggin PF05806.12 KXZ56152.1 - 1 9.2 4.8 1.2 9.0 3.0 2.0 2 0 0 2 2 2 0 Noggin TFIIA PF03153.13 KXZ56152.1 - 4.9 7.0 13.3 7 6.5 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Atg14 PF10186.9 KXZ56152.1 - 6.7 5.7 16.6 11 5.0 16.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaF PF07309.11 KXZ56154.1 - 0.021 14.8 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Flagellar protein FlaF WD40 PF00400.32 KXZ56155.1 - 4.2e-14 52.7 4.2 9e-06 26.3 0.4 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56155.1 - 1.7e-06 28.2 0.0 0.39 11.0 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain LRR_8 PF13855.6 KXZ56156.1 - 3.5e-12 45.9 7.3 1.3e-08 34.5 0.5 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KXZ56156.1 - 2.9e-10 40.2 1.2 0.0066 16.8 0.0 3.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Patatin PF01734.22 KXZ56156.1 - 1.2e-06 28.8 2.6 1.2e-06 28.8 2.6 4.3 4 1 0 4 4 4 1 Patatin-like phospholipase LRR_6 PF13516.6 KXZ56156.1 - 0.39 10.9 1.7 44 4.5 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KXZ56156.1 - 0.58 10.9 4.5 63 4.7 0.2 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat Gly_transf_sug PF04488.15 KXZ56157.1 - 8.1e-10 39.2 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 KXZ56157.1 - 5.6e-05 23.3 0.0 0.00011 22.4 0.0 1.6 1 1 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Caps_synth PF05704.12 KXZ56157.1 - 0.00081 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Pkinase_Tyr PF07714.17 KXZ56159.1 - 1.8e-33 116.0 0.0 8.1e-16 58.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KXZ56159.1 - 3.9e-30 105.1 0.0 1.2e-15 57.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KXZ56159.1 - 0.00094 18.6 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ56159.1 - 0.011 15.7 0.3 0.18 11.7 0.0 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Herpes_gE PF02480.16 KXZ56159.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E HARE-HTH PF05066.13 KXZ56160.1 - 0.02 15.3 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Cyclin_C PF02984.19 KXZ56161.1 - 0.091 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 KXZ56162.1 - 1.9e-18 67.1 0.0 2.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ56162.1 - 8.4e-08 32.6 0.0 1.3e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop PF01798.18 KXZ56164.1 - 2.6e-72 243.0 0.0 3.7e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KXZ56164.1 - 5.1e-41 140.4 1.9 1e-40 139.4 1.9 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain CR6_interact PF10147.9 KXZ56164.1 - 0.23 11.2 3.1 2.8 7.6 1.1 2.3 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Pkinase_Tyr PF07714.17 KXZ56165.1 - 1.3e-19 70.5 0.0 1e-16 61.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56165.1 - 4.3e-17 62.3 0.0 4e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KXZ56165.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMA PF00403.26 KXZ56166.1 - 8.4e-11 42.2 0.1 1.2e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 KXZ56166.1 - 0.0011 19.3 0.2 0.0018 18.6 0.2 1.4 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain E1-E2_ATPase PF00122.20 KXZ56167.1 - 4.4e-47 159.9 2.4 1.1e-45 155.4 0.3 2.4 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KXZ56167.1 - 1.4e-33 117.0 12.3 3.3e-33 115.7 12.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXZ56167.1 - 5.5e-06 26.3 1.3 0.00019 21.3 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXZ56167.1 - 0.00058 20.3 1.1 0.0012 19.2 1.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CwsA PF10814.8 KXZ56168.1 - 0.058 13.6 4.7 0.074 13.2 4.7 1.2 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Cyclin_C PF02984.19 KXZ56170.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain HTH_9 PF08221.11 KXZ56170.1 - 0.23 11.6 0.0 0.62 10.2 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Romo1 PF10247.9 KXZ56171.1 - 0.059 13.7 3.7 0.45 10.9 0.3 2.9 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Rax2 PF12768.7 KXZ56171.1 - 0.16 11.4 0.3 0.24 10.8 0.3 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.20 KXZ56171.1 - 2 8.4 3.5 4.3 7.3 3.5 1.5 1 0 0 1 1 1 0 Syndecan domain PfkB PF00294.24 KXZ56172.1 - 1.4e-58 198.6 1.5 1.7e-58 198.3 1.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXZ56172.1 - 2.8e-10 40.0 0.3 5.7e-10 39.0 0.1 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 KXZ56172.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate kinase DUF5608 PF18356.1 KXZ56172.1 - 0.062 13.3 0.1 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5608) Porin_3 PF01459.22 KXZ56173.1 - 2.3e-59 201.1 0.0 2.6e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin MDM10 PF12519.8 KXZ56173.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ank_2 PF12796.7 KXZ56174.1 - 8.8e-14 51.9 0.5 0.0004 20.9 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ56174.1 - 1.4e-12 47.9 4.3 0.055 14.1 0.0 7.5 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56174.1 - 0.0004 20.6 0.5 73 4.4 0.0 6.5 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 KXZ56174.1 - 0.00095 19.4 8.6 8.4 6.9 0.0 7.5 6 3 3 9 9 9 1 Ankyrin repeats (many copies) F-box PF00646.33 KXZ56174.1 - 0.088 12.7 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 F-box domain DUF1843 PF08898.10 KXZ56174.1 - 0.29 11.6 4.8 36 4.9 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Proteasome PF00227.26 KXZ56175.1 - 1.8e-47 161.3 0.3 2.3e-47 160.9 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KXZ56175.1 - 0.02 14.3 0.6 0.085 12.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome beta subunits C terminal DA1-like PF12315.8 KXZ56176.1 - 1.3e-42 145.5 0.3 3.9e-40 137.5 0.3 2.6 1 1 0 1 1 1 1 Protein DA1 LIM PF00412.22 KXZ56176.1 - 4.9e-07 29.9 12.3 6.1e-07 29.6 0.9 3.4 1 1 2 3 3 3 2 LIM domain Kinesin PF00225.23 KXZ56177.1 - 5e-77 259.1 0.0 7.8e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ56177.1 - 4.9e-16 59.0 0.0 1.1e-12 48.2 0.0 2.3 2 0 0 2 2 2 2 Microtubule binding VGPC1_C PF16799.5 KXZ56177.1 - 0.37 10.8 0.9 0.74 9.8 0.9 1.5 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF4586 PF15239.6 KXZ56178.1 - 4e-05 24.0 1.7 7e-05 23.2 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) DUF4541 PF15074.6 KXZ56178.1 - 0.042 14.4 1.7 0.79 10.4 1.7 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4541) DUF2040 PF09745.9 KXZ56178.1 - 0.33 11.0 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Ku PF02735.16 KXZ56179.1 - 2.5e-25 89.4 0.0 6.8e-25 88.0 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KXZ56179.1 - 5.1e-20 71.8 0.0 8.4e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KXZ56179.1 - 0.0044 16.8 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SRCR PF00530.18 KXZ56180.1 - 4.5e-07 30.3 0.0 6.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SYS1 PF09801.9 KXZ56181.1 - 6.4e-40 136.6 7.2 7.6e-40 136.4 7.2 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Tweety PF04906.13 KXZ56181.1 - 0.29 9.8 3.2 0.48 9.0 3.2 1.3 1 0 0 1 1 1 0 Tweety Spc7 PF08317.11 KXZ56182.1 - 0.74 8.6 21.0 0.28 10.0 1.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 KXZ56182.1 - 9.5 5.6 24.4 5.8 6.3 4.0 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Pyrophosphatase PF00719.19 KXZ56183.1 - 4.2e-46 156.7 0.5 5.6e-46 156.3 0.5 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase TFIIA_gamma_C PF02751.14 KXZ56184.1 - 1e-09 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KXZ56184.1 - 1e-07 31.9 0.1 1.4e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF4497 PF14924.6 KXZ56185.1 - 1.2e-10 41.9 0.0 2.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4497) PBP1_TM PF14812.6 KXZ56185.1 - 1.9 8.9 21.7 1.7 9.0 2.6 5.3 4 1 1 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_1 PF00036.32 KXZ56187.1 - 9.8e-05 21.6 0.1 0.00031 20.1 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXZ56187.1 - 0.00022 20.6 0.1 0.00066 19.1 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ56187.1 - 0.0071 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXZ56187.1 - 0.06 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair RicinB_lectin_2 PF14200.6 KXZ56188.1 - 6.1e-24 84.6 0.2 7.9e-15 55.4 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like VOMI PF03762.17 KXZ56188.1 - 1.1e-12 48.4 1.6 1.5e-08 35.0 0.3 3.0 1 1 1 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) Ricin_B_lectin PF00652.22 KXZ56188.1 - 4.2e-12 46.4 0.2 4.1e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KXZ56188.1 - 0.0055 16.3 0.1 0.22 11.1 0.0 2.2 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain LysM PF01476.20 KXZ56189.1 - 8.6e-12 44.9 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 LysM domain RicinB_lectin_2 PF14200.6 KXZ56189.1 - 2.9e-09 37.5 1.8 1.9e-07 31.7 0.1 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KXZ56189.1 - 5.8e-08 33.0 1.5 1.3e-05 25.4 0.0 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain DNA_pol_E_B PF04042.16 KXZ56190.1 - 1.8e-36 125.5 0.0 3.2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B tRNA_bind PF01588.20 KXZ56191.1 - 4.8e-25 87.5 0.1 8e-25 86.8 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain FAP PF07174.11 KXZ56191.1 - 2.8 7.3 24.0 4.6 6.6 24.0 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF1712 PF08217.11 KXZ56192.1 - 0.0025 16.4 0.0 0.013 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Flavin_Reduct PF01613.18 KXZ56193.1 - 5e-20 72.1 0.5 6.9e-20 71.7 0.5 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 KXZ56193.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.12 KXZ56193.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF447) EamA PF00892.20 KXZ56194.1 - 0.00011 22.3 8.7 0.00011 22.3 8.7 1.6 1 1 1 2 2 2 1 EamA-like transporter family TPT PF03151.16 KXZ56194.1 - 0.0015 17.9 5.0 0.0018 17.7 5.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXZ56194.1 - 0.045 12.9 2.2 0.058 12.6 2.2 1.2 1 0 0 1 1 1 0 UAA transporter family NicO PF03824.16 KXZ56194.1 - 3.2 7.0 9.2 1.6 8.0 4.8 2.1 1 1 1 2 2 2 0 High-affinity nickel-transport protein PAP2 PF01569.21 KXZ56195.1 - 2e-05 24.4 10.0 2e-05 24.4 10.0 3.1 1 1 0 2 2 2 1 PAP2 superfamily BDV_G PF06208.11 KXZ56195.1 - 0.042 13.0 1.1 0.059 12.5 1.1 1.1 1 0 0 1 1 1 0 Borna disease virus G protein FlaC_arch PF05377.11 KXZ56196.1 - 0.013 15.8 2.0 2.6 8.5 0.1 4.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 KXZ56196.1 - 0.017 15.2 0.7 0.18 12.0 0.3 2.8 2 0 0 2 2 2 0 bZIP transcription factor HOOK PF05622.12 KXZ56196.1 - 0.023 12.9 1.2 0.15 10.2 0.1 2.2 2 0 0 2 2 2 0 HOOK protein Snapin_Pallidin PF14712.6 KXZ56196.1 - 0.034 14.6 8.3 0.3 11.5 0.0 3.9 4 0 0 4 4 4 0 Snapin/Pallidin HMMR_N PF15905.5 KXZ56196.1 - 0.039 13.4 0.1 1.5 8.2 0.1 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Myc-LZ PF02344.15 KXZ56196.1 - 0.04 14.0 1.1 0.099 12.8 1.1 1.7 1 0 0 1 1 1 0 Myc leucine zipper domain GAS PF13851.6 KXZ56196.1 - 0.054 12.8 1.5 0.068 12.5 0.1 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 KXZ56196.1 - 0.056 12.9 5.4 0.077 12.5 0.1 2.9 3 0 0 3 3 3 0 Golgin subfamily A member 5 Phage_GP20 PF06810.11 KXZ56196.1 - 0.088 12.6 1.0 0.23 11.3 0.1 2.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 KXZ56196.1 - 0.18 12.3 13.8 18 5.9 0.5 5.9 4 2 3 7 7 7 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KXZ56196.1 - 0.22 11.8 8.4 31 5.0 0.1 4.8 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1515 PF07439.11 KXZ56196.1 - 0.37 10.8 5.8 6.5 6.8 0.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) HALZ PF02183.18 KXZ56196.1 - 0.45 10.8 1.6 22 5.4 0.2 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Filament PF00038.21 KXZ56196.1 - 0.74 9.3 5.8 0.16 11.5 0.9 2.2 2 1 0 2 2 2 0 Intermediate filament protein FlxA PF14282.6 KXZ56196.1 - 1 9.4 5.3 3.5 7.7 0.1 3.3 4 0 0 4 4 3 0 FlxA-like protein MPS2 PF17060.5 KXZ56196.1 - 1 8.5 2.0 21 4.3 0.2 2.9 2 1 2 4 4 4 0 Monopolar spindle protein 2 HAUS-augmin3 PF14932.6 KXZ56196.1 - 1.1 8.8 7.6 0.15 11.6 0.2 2.7 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Fez1 PF06818.15 KXZ56196.1 - 1.8 9.0 7.7 3.2 8.2 1.0 2.9 2 1 1 3 3 3 0 Fez1 Lzipper-MIP1 PF14389.6 KXZ56196.1 - 3.4 8.0 7.5 1.3 9.4 0.9 3.3 4 0 0 4 4 3 0 Leucine-zipper of ternary complex factor MIP1 Baculo_PEP_C PF04513.12 KXZ56196.1 - 3.6 7.6 11.3 9.3 6.3 0.1 3.7 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 KXZ56196.1 - 3.8 7.3 10.3 0.67 9.8 0.1 4.3 5 1 1 6 6 5 0 Spindle and kinetochore-associated protein 2 bZIP_2 PF07716.15 KXZ56196.1 - 4.5 7.4 6.4 3.4 7.8 1.9 3.2 3 0 0 3 3 3 0 Basic region leucine zipper FliJ PF02050.16 KXZ56196.1 - 5.3 7.3 14.2 3.1 8.0 0.1 4.3 3 2 2 5 5 5 0 Flagellar FliJ protein Dynamitin PF04912.14 KXZ56196.1 - 6.7 5.9 13.8 0.43 9.8 0.8 2.6 2 1 0 2 2 2 0 Dynamitin APG6_N PF17675.1 KXZ56196.1 - 8.2 7.0 8.0 1.9 9.1 0.0 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KXZ56196.1 - 8.8 6.6 11.8 0.33 11.2 0.3 3.6 3 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding JmjC PF02373.22 KXZ56197.1 - 3.9e-09 36.9 0.1 2e-07 31.4 0.1 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KXZ56197.1 - 3.5e-07 30.2 0.0 7.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Cupin-like domain APH PF01636.23 KXZ56197.1 - 1.4e-05 25.1 0.6 0.12 12.3 0.0 3.3 3 1 0 3 3 3 2 Phosphotransferase enzyme family DUF4719 PF15843.5 KXZ56198.1 - 1.9 8.6 8.4 0.42 10.7 5.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4719) Glycos_transf_1 PF00534.20 KXZ56199.1 - 8.6e-10 38.4 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ56199.1 - 3.9e-09 37.0 0.0 6.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Formyl_trans_N PF00551.19 KXZ56199.1 - 0.2 11.3 0.1 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Formyl transferase ATG16 PF08614.11 KXZ56200.1 - 0.00036 20.8 12.0 0.00036 20.8 12.0 8.5 3 3 5 8 8 8 3 Autophagy protein 16 (ATG16) Filament PF00038.21 KXZ56200.1 - 0.0011 18.7 32.7 0.0011 18.7 32.7 7.8 3 3 4 7 7 7 4 Intermediate filament protein KELK PF15796.5 KXZ56200.1 - 0.0021 18.4 2.3 0.0021 18.4 2.3 10.4 7 4 4 11 11 11 4 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_TATA_bd PF12325.8 KXZ56200.1 - 0.015 15.5 1.4 0.015 15.5 1.4 10.9 3 3 7 12 12 12 0 TATA element modulatory factor 1 TATA binding EamA PF00892.20 KXZ56201.1 - 0.012 15.8 3.0 0.02 15.1 3.0 1.4 1 0 0 1 1 1 0 EamA-like transporter family GvpL_GvpF PF06386.11 KXZ56202.1 - 0.0011 18.9 1.2 0.0011 18.9 1.2 3.6 3 1 1 4 4 4 1 Gas vesicle synthesis protein GvpL/GvpF WD40 PF00400.32 KXZ56203.1 - 4.9e-11 43.0 0.1 0.014 16.2 0.0 3.6 2 1 1 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56203.1 - 8.6e-05 22.8 0.0 2.3 8.6 0.0 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXZ56203.1 - 0.11 12.5 0.4 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KXZ56203.1 - 1.5 8.6 5.1 28 4.5 0.0 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KXZ56204.1 - 9.4e-07 29.4 0.0 1 10.3 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat PQQ_2 PF13360.6 KXZ56204.1 - 0.0029 17.2 0.0 0.0077 15.8 0.0 1.7 1 1 1 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KXZ56204.1 - 0.017 15.4 0.0 0.12 12.7 0.0 2.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Yip1 PF04893.17 KXZ56205.1 - 9.1e-10 38.5 19.6 1.3e-09 38.0 19.6 1.2 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 KXZ56205.1 - 0.26 10.8 2.8 0.43 10.0 2.8 1.2 1 0 0 1 1 1 0 YIF1 Vps5 PF09325.10 KXZ56206.1 - 1.5e-10 41.0 9.6 7.6e-10 38.7 9.6 1.8 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXZ56206.1 - 2.5e-09 37.1 1.6 3.8e-09 36.5 0.1 2.1 3 0 0 3 3 3 1 PX domain Uso1_p115_C PF04871.13 KXZ56206.1 - 1.7 9.0 9.3 0.068 13.5 2.7 2.0 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Phasin_2 PF09361.10 KXZ56206.1 - 5.3 7.4 7.4 4.5 7.6 0.6 3.0 3 1 0 3 3 3 0 Phasin protein Ribosomal_L38e PF01781.18 KXZ56207.1 - 2.2e-35 120.6 1.6 2.4e-35 120.5 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2384 PF09722.10 KXZ56208.1 - 0.096 12.7 0.6 3.9 7.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) zf-CCCH_2 PF14608.6 KXZ56209.1 - 0.17 12.4 1.8 0.33 11.5 1.8 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger BAF1_ABF1 PF04684.13 KXZ56209.1 - 3.8 6.4 10.8 7.1 5.6 10.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SPX PF03105.19 KXZ56210.1 - 8.2e-15 55.6 0.0 8.2e-15 55.6 0.0 4.2 2 2 1 3 3 3 2 SPX domain Rrn6 PF10214.9 KXZ56210.1 - 6.4 5.1 7.9 9.3 4.6 7.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AAA PF00004.29 KXZ56212.1 - 3e-13 50.4 0.0 7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AP3D1 PF06375.11 KXZ56212.1 - 0.00016 22.0 22.3 0.00086 19.6 8.8 3.0 3 0 0 3 3 3 2 AP-3 complex subunit delta-1 IQ PF00612.27 KXZ56212.1 - 0.00051 19.6 6.9 0.004 16.8 3.6 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 KXZ56212.1 - 0.17 12.2 0.0 40 4.5 0.0 3.1 1 1 1 2 2 2 0 AAA domain DUF2293 PF10056.9 KXZ56212.1 - 0.29 11.4 2.9 0.47 10.7 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) ORC_WH_C PF18137.1 KXZ56212.1 - 0.37 10.9 6.4 5.1 7.2 0.8 2.7 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal GEN1_C PF18380.1 KXZ56212.1 - 0.59 11.1 5.7 14 6.7 0.5 2.8 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain SNF2_N PF00176.23 KXZ56213.1 - 3.9e-62 210.0 0.0 1.1e-61 208.5 0.0 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ56213.1 - 4.6e-16 59.2 0.0 5.3e-14 52.5 0.0 3.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ56213.1 - 4.6e-08 33.3 0.0 1.4e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXZ56213.1 - 3e-05 23.9 0.0 0.00012 21.9 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.6 KXZ56213.1 - 0.041 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXZ56213.1 - 0.065 13.5 0.1 0.81 10.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain FliH PF02108.16 KXZ56214.1 - 0.042 13.9 1.2 0.079 13.0 1.2 1.4 1 0 0 1 1 1 0 Flagellar assembly protein FliH Mpp10 PF04006.12 KXZ56214.1 - 3.1 6.1 20.5 5.5 5.3 20.5 1.3 1 0 0 1 1 1 0 Mpp10 protein zf-MYND PF01753.18 KXZ56215.1 - 1.7 8.8 7.2 0.073 13.2 0.8 2.0 2 0 0 2 2 2 0 MYND finger zf-MYND PF01753.18 KXZ56216.1 - 5.6e-09 36.0 13.0 1.2e-08 34.9 13.0 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXZ56216.1 - 0.52 10.6 8.3 1.1 9.6 8.3 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Hydantoinase_B PF02538.14 KXZ56217.1 - 1e-207 690.7 0.4 1e-207 690.7 0.4 1.7 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXZ56217.1 - 1.7e-92 309.8 2.9 3e-61 207.3 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXZ56217.1 - 1.9e-72 242.7 0.0 1.9e-38 131.9 0.0 3.5 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase N-terminal region ABC_membrane PF00664.23 KXZ56223.1 - 4.5e-06 26.5 2.5 6.2e-06 26.1 2.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF846 PF05832.12 KXZ56223.1 - 1.4 9.0 6.0 0.7 9.9 0.5 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) ABC_membrane PF00664.23 KXZ56224.1 - 1.8e-25 90.1 0.6 2.3e-25 89.8 0.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Oleosin PF01277.17 KXZ56224.1 - 4.5 7.1 9.2 11 5.8 4.0 2.4 2 0 0 2 2 2 0 Oleosin Pkinase PF00069.25 KXZ56225.1 - 3.5e-31 108.5 0.0 4.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56225.1 - 1.2e-27 96.9 0.0 1.5e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXZ56225.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family FGGY_N PF00370.21 KXZ56226.1 - 3.2e-30 105.5 0.0 4.4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KXZ56226.1 - 4.2e-26 91.9 0.1 8.8e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GAF PF01590.26 KXZ56226.1 - 0.00016 22.3 0.1 0.0029 18.3 0.1 2.7 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KXZ56226.1 - 0.0055 17.0 0.1 0.024 14.9 0.1 2.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KXZ56226.1 - 0.028 14.8 0.1 0.028 14.8 0.1 2.7 4 0 0 4 4 4 0 GAF domain DEAD PF00270.29 KXZ56228.1 - 1.8e-24 86.5 0.0 3.3e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ56228.1 - 2.3e-22 79.5 0.0 9.4e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ56228.1 - 0.00022 21.3 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ABC1 PF03109.16 KXZ56229.1 - 1.5e-24 86.5 0.0 2.1e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.17 KXZ56229.1 - 0.14 11.4 0.0 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KXZ56231.1 - 8.4e-54 182.6 0.0 2.8e-50 171.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56231.1 - 1.5e-48 165.5 0.0 5.5e-48 163.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain CBS PF00571.28 KXZ56231.1 - 2.1e-11 44.1 0.0 2.7e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 CBS domain FAM199X PF15814.5 KXZ56231.1 - 0.065 12.3 2.3 0.1 11.6 2.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Haspin_kinase PF12330.8 KXZ56231.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain KH_6 PF15985.5 KXZ56233.1 - 6.3e-15 55.3 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 KH domain SpoVIF PF14069.6 KXZ56233.1 - 0.19 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Stage VI sporulation protein F DUF4644 PF15486.6 KXZ56234.1 - 0.011 15.6 1.1 0.014 15.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) DUF4519 PF15012.6 KXZ56235.1 - 2e-06 27.8 0.1 2.5e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) Trp_oprn_chp PF09534.10 KXZ56235.1 - 0.00077 19.3 0.0 0.00085 19.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TRIQK PF15168.6 KXZ56235.1 - 0.0096 15.8 0.1 0.0096 15.8 0.1 1.4 2 0 0 2 2 2 1 Triple QxxK/R motif-containing protein family DUF2157 PF09925.9 KXZ56235.1 - 0.022 14.5 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF3040 PF11239.8 KXZ56235.1 - 0.037 14.3 0.1 0.053 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2207 PF09972.9 KXZ56235.1 - 0.055 12.2 0.0 0.055 12.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2408 PF10303.9 KXZ56236.1 - 0.1 13.2 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ABC_tran_CTD PF16326.5 KXZ56236.1 - 0.19 12.0 4.9 0.28 11.5 1.8 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain CCDC53 PF10152.9 KXZ56236.1 - 0.33 11.3 2.5 0.44 10.9 2.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DnaJ_C PF01556.18 KXZ56237.1 - 4.5e-35 120.9 0.0 6.5e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXZ56237.1 - 1.4e-17 63.6 2.1 2.4e-17 62.8 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain Kelch_4 PF13418.6 KXZ56238.1 - 1.4e-22 79.4 7.7 4.4e-07 29.8 0.2 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KXZ56238.1 - 6.6e-20 70.9 24.1 3.5e-09 36.7 0.5 5.4 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KXZ56238.1 - 2.4e-18 65.7 2.5 2.5e-05 24.1 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KXZ56238.1 - 3.3e-18 65.0 6.0 3.3e-06 26.6 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KXZ56238.1 - 1.4e-12 47.1 4.3 0.00033 20.5 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KXZ56238.1 - 1.3e-10 41.1 4.8 0.002 18.3 0.1 4.7 2 1 3 5 5 5 2 Kelch motif PACT_coil_coil PF10495.9 KXZ56238.1 - 0.025 15.2 13.9 0.056 14.0 1.7 2.9 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein BBP1_C PF15272.6 KXZ56238.1 - 0.11 12.3 9.1 0.052 13.4 2.6 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Pox_A_type_inc PF04508.12 KXZ56238.1 - 7.7 6.5 6.4 3.5 7.6 0.5 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF2045 PF09741.9 KXZ56240.1 - 5.1e-23 81.7 0.0 7.1e-21 74.7 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2045) DUF4232 PF14016.6 KXZ56240.1 - 1.3 9.2 6.3 1.6 8.9 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4232) Laminin_G_3 PF13385.6 KXZ56241.1 - 6e-44 149.8 10.9 9.2e-18 64.8 0.2 7.0 4 3 0 4 4 4 4 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 KXZ56241.1 - 7.5e-39 133.4 0.0 1.4e-12 47.7 0.0 5.1 3 2 0 3 3 3 3 Pentaxin family Laminin_G_2 PF02210.24 KXZ56241.1 - 2.1e-11 44.5 0.0 0.023 15.3 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 KXZ56241.1 - 0.056 13.7 0.0 19 5.5 0.0 3.5 4 0 0 4 4 4 0 Laminin G domain CEND1 PF15677.5 KXZ56241.1 - 0.1 13.1 2.7 0.24 12.0 2.7 1.6 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Sec2p PF06428.11 KXZ56242.1 - 0.0051 16.8 3.7 0.059 13.3 1.0 2.1 1 1 1 2 2 2 2 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 KXZ56242.1 - 0.03 13.2 1.0 0.08 11.8 1.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DnaJ PF00226.31 KXZ56243.1 - 8.6e-18 64.2 0.1 2e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 KXZ56243.1 - 3.1e-15 56.4 2.8 3.1e-15 56.4 2.8 2.4 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KXZ56243.1 - 3e-06 27.9 5.2 3e-06 27.9 5.2 3.1 3 1 0 3 3 3 1 4Fe-4S single cluster domain Fer4 PF00037.27 KXZ56243.1 - 0.072 12.9 1.2 0.072 12.9 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Chloroa_b-bind PF00504.21 KXZ56244.1 - 2.4e-10 41.2 3.0 2.8e-07 31.2 0.3 2.1 1 1 1 2 2 2 2 Chlorophyll A-B binding protein FAE1_CUT1_RppA PF08392.12 KXZ56245.1 - 3.4e-79 266.2 0.0 1e-78 264.6 0.0 1.6 1 1 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_N PF00195.19 KXZ56245.1 - 9.7e-08 31.7 0.1 1.4e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 KXZ56245.1 - 1.6e-07 31.4 0.0 3.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 KXZ56245.1 - 2.2e-07 30.9 0.1 1.1e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KXZ56245.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF5487 PF17589.2 KXZ56245.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5487) TRAPP PF04051.16 KXZ56245.1 - 0.14 11.9 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component PCMT PF01135.19 KXZ56245.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAST_1 PF06743.15 KXZ56246.1 - 0.00016 21.5 2.5 8.4 6.4 0.0 6.0 8 1 0 8 8 8 2 FAST kinase-like protein, subdomain 1 SnoaL_2 PF12680.7 KXZ56247.1 - 0.001 19.7 0.0 0.0014 19.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain TAT_signal PF10518.9 KXZ56247.1 - 0.016 15.0 0.0 0.016 15.0 0.0 2.8 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Asn_synthase PF00733.21 KXZ56248.1 - 2.4e-12 47.2 0.9 8.8e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXZ56248.1 - 0.003 17.4 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain LBR_tudor PF09465.10 KXZ56248.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF2783 PF10932.8 KXZ56248.1 - 0.096 12.4 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) PhyH PF05721.13 KXZ56249.1 - 3.9e-12 46.9 0.3 8.6e-11 42.5 0.3 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_1 PF00232.18 KXZ56250.1 - 9e-58 195.8 0.0 5.1e-57 193.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 KXZ56250.1 - 4.4e-08 32.9 0.0 5.1e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RNase_H2-Ydr279 PF09468.10 KXZ56251.1 - 8.4e-08 32.6 0.0 2e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KXZ56251.1 - 0.00016 21.8 0.0 0.95 9.8 0.0 2.4 2 0 0 2 2 2 2 Ydr279p protein triple barrel domain Glutaredoxin PF00462.24 KXZ56252.1 - 6e-19 68.0 0.0 8.9e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 KXZ56252.1 - 0.0048 17.0 0.0 0.0076 16.4 0.0 1.4 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 KXZ56252.1 - 0.088 13.2 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Guanylate_cyc PF00211.20 KXZ56253.1 - 3.9e-60 202.6 0.0 5.5e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KXZ56253.1 - 2.3e-44 151.5 0.0 1.4e-27 96.6 0.1 2.2 1 1 1 2 2 2 2 Heme NO binding associated HNOB PF07700.15 KXZ56253.1 - 1.1e-07 31.9 0.0 1.8e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding SET PF00856.28 KXZ56254.1 - 0.0017 18.8 0.0 0.0035 17.8 0.0 1.6 1 0 0 1 1 1 1 SET domain Kelch_1 PF01344.25 KXZ56255.1 - 0.066 12.8 0.4 35 4.1 0.0 3.2 3 0 0 3 3 3 0 Kelch motif bPH_2 PF03703.14 KXZ56256.1 - 3.6e-08 33.5 0.1 5.1e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial PH domain bPH_3 PF14470.6 KXZ56256.1 - 0.0069 16.7 0.0 0.0094 16.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain PhoD PF09423.10 KXZ56257.1 - 2.3e-11 43.3 0.0 3.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase bZIP_1 PF00170.21 KXZ56258.1 - 4.2e-08 33.2 7.3 4.2e-08 33.2 7.3 2.7 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KXZ56258.1 - 0.01 15.9 22.6 0.038 14.1 11.8 4.0 2 1 2 4 4 4 0 Basic region leucine zipper ADP_PFK_GK PF04587.15 KXZ56258.1 - 0.098 11.2 5.5 0.13 10.8 5.5 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region IDEAL PF08858.10 KXZ56258.1 - 1.1 9.0 5.1 0.22 11.3 1.4 1.8 2 0 0 2 2 2 0 IDEAL domain Endonuc_Holl PF10107.9 KXZ56258.1 - 3.2 7.6 9.1 0.32 10.8 0.1 2.1 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF16 PF01519.16 KXZ56258.1 - 4.8 7.7 12.0 30 5.2 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF5320 PF17253.2 KXZ56258.1 - 6.2 8.0 12.9 0.44 11.7 5.0 2.5 1 1 2 3 3 3 0 Family of unknown function (DUF5320) Cyclin_N PF00134.23 KXZ56259.1 - 2.4e-13 49.9 0.1 1.6e-11 44.1 0.3 2.5 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KXZ56259.1 - 0.00084 19.3 0.1 0.55 10.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KXZ56259.1 - 0.004 17.2 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain MutL_C PF08676.11 KXZ56259.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 MutL C terminal dimerisation domain DUF3806 PF12713.7 KXZ56259.1 - 0.036 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) Peptidase_U49 PF10463.9 KXZ56259.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase U49 ADH_N PF08240.12 KXZ56260.1 - 8.1e-27 93.3 0.3 8.1e-27 93.3 0.3 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXZ56260.1 - 1.1e-09 38.4 1.1 9.7e-05 22.4 0.1 3.2 2 1 1 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXZ56260.1 - 0.00031 20.6 0.0 0.00088 19.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KXZ56260.1 - 0.00085 20.4 0.0 0.0032 18.5 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXZ56260.1 - 0.0045 16.5 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KXZ56260.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KXZ56260.1 - 0.049 13.9 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXZ56260.1 - 0.06 12.0 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KXZ56260.1 - 0.15 11.6 1.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KXZ56260.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 KXZ56261.1 - 0.00045 20.2 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KXZ56261.1 - 0.084 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Ribosomal_L19 PF01245.20 KXZ56262.1 - 1.8e-16 60.0 0.0 2.5e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 PHO4 PF01384.20 KXZ56263.1 - 4.1e-82 275.9 22.4 8e-82 275.0 22.4 1.4 1 0 0 1 1 1 1 Phosphate transporter family SET PF00856.28 KXZ56264.1 - 7.4e-17 62.2 0.0 7.4e-17 62.2 0.0 4.0 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KXZ56264.1 - 6.7e-11 42.0 5.4 2e-10 40.6 5.4 1.7 1 0 0 1 1 1 1 AWS domain PWWP PF00855.17 KXZ56264.1 - 0.046 14.1 0.4 0.12 12.8 0.4 1.7 1 0 0 1 1 1 0 PWWP domain LBR_tudor PF09465.10 KXZ56264.1 - 0.079 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Helicase_C_2 PF13307.6 KXZ56265.1 - 3.2e-45 154.3 0.0 1.3e-44 152.4 0.0 1.8 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXZ56265.1 - 5.9e-20 71.6 0.0 8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 MoaE PF02391.17 KXZ56266.1 - 5.4e-17 62.1 0.0 1.8e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 MoaE protein DUF2113 PF09886.9 KXZ56266.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) Epimerase PF01370.21 KXZ56267.1 - 1.8e-17 63.7 0.0 3.1e-17 62.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ56267.1 - 5.2e-12 45.3 0.0 6.6e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXZ56267.1 - 1.1e-11 45.0 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXZ56267.1 - 1.8e-07 30.6 0.0 3.4e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXZ56267.1 - 1.3e-06 28.1 0.0 1.8e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXZ56267.1 - 1.8e-05 24.4 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KXZ56267.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXZ56267.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Nramp PF01566.18 KXZ56268.1 - 6.2e-120 400.4 17.8 7.9e-120 400.1 17.8 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein PQQ_2 PF13360.6 KXZ56269.1 - 0.00032 20.4 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain DUF463 PF04317.12 KXZ56272.1 - 0.05 12.5 0.7 5.8 5.7 0.0 2.1 1 1 1 2 2 2 0 YcjX-like family, DUF463 RIF5_SNase_2 PF18189.1 KXZ56272.1 - 0.35 10.7 1.8 8.8 6.1 0.2 2.3 1 1 1 2 2 2 0 TbRIF5 SNase domain 2 PQQ_2 PF13360.6 KXZ56273.1 - 1.2e-09 38.2 0.0 5.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KXZ56273.1 - 0.0098 15.8 0.0 32 4.7 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat Pkinase_Tyr PF07714.17 KXZ56274.1 - 9.7e-32 110.3 0.0 4.9e-30 104.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ56274.1 - 9.4e-31 107.1 0.0 3.5e-30 105.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KXZ56274.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KXZ56274.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.6 4 0 0 4 4 4 0 Phosphotransferase enzyme family Aminotran_5 PF00266.19 KXZ56275.1 - 7.1e-54 183.2 1.0 2.4e-52 178.1 1.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-V Sde2_N_Ubi PF13019.6 KXZ56277.1 - 1.3e-17 64.1 7.4 2.4e-17 63.2 7.1 1.5 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain ubiquitin PF00240.23 KXZ56277.1 - 1.4e-15 56.8 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXZ56277.1 - 0.0063 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RNA_pol_Rpb2_1 PF04563.15 KXZ56278.1 - 1.1e-31 110.0 0.0 2.1e-31 109.0 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KXZ56278.1 - 1.2e-27 95.9 0.0 2.5e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KXZ56278.1 - 4.6e-13 49.2 0.0 7.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 SMN PF06003.12 KXZ56279.1 - 7.1e-09 35.3 0.0 7.1e-09 35.3 0.0 1.8 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KXZ56279.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Tudor domain Tudor_2 PF18104.1 KXZ56279.1 - 0.17 11.6 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain IQ PF00612.27 KXZ56281.1 - 0.00026 20.5 10.2 0.0036 17.0 2.2 3.6 4 0 0 4 4 4 2 IQ calmodulin-binding motif Lactamase_B_2 PF12706.7 KXZ56282.1 - 0.0018 17.9 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aha1_N PF09229.11 KXZ56283.1 - 1.2e-22 80.6 0.0 1.8e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal PseudoU_synth_2 PF00849.22 KXZ56284.1 - 5e-16 59.2 0.0 3.2e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KXZ56284.1 - 0.0028 17.3 0.5 0.0058 16.3 0.5 1.6 1 0 0 1 1 1 1 S4 domain DUF3119 PF11317.8 KXZ56286.1 - 4.7e-47 159.4 0.0 5.8e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) T2SSC PF11356.8 KXZ56286.1 - 0.0038 17.1 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Type II secretion system protein C Rad60-SLD PF11976.8 KXZ56286.1 - 0.2 11.5 0.1 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like La PF05383.17 KXZ56287.1 - 2.6e-22 78.6 0.0 5.4e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXZ56287.1 - 0.024 14.4 0.2 11 5.9 0.1 2.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpvB PF03534.13 KXZ56287.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein 4HBT PF03061.22 KXZ56288.1 - 3.5e-12 46.5 2.2 3.5e-12 46.5 2.2 1.6 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 KXZ56288.1 - 4.2e-06 26.9 0.5 7.3e-06 26.2 0.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KXZ56288.1 - 0.00063 20.1 3.7 0.00094 19.5 3.7 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.25 KXZ56289.1 - 7.7e-40 136.9 0.0 1.1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56289.1 - 1e-23 83.9 0.0 1.4e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ56289.1 - 0.00031 20.2 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXZ56289.1 - 0.015 14.7 2.5 0.054 12.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PEN-2 PF10251.9 KXZ56290.1 - 9.5e-14 51.6 0.8 1.3e-13 51.2 0.8 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF2569 PF10754.9 KXZ56290.1 - 0.013 15.9 0.1 0.018 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) EMC3_TMCO1 PF01956.16 KXZ56290.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MCU PF04678.13 KXZ56290.1 - 0.34 11.0 1.0 1.9 8.6 1.0 2.0 1 1 0 1 1 1 0 Mitochondrial calcium uniporter E2F_TDP PF02319.20 KXZ56291.1 - 5e-24 84.1 0.5 1e-23 83.2 0.5 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 KXZ56291.1 - 2.7e-19 69.5 0.4 2.7e-19 69.5 0.4 2.5 4 0 0 4 4 4 1 Transcription factor DP CI-B14_5a PF07347.12 KXZ56291.1 - 0.16 11.9 2.6 0.52 10.2 1.0 2.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) NAD_kinase PF01513.21 KXZ56292.1 - 1.8e-56 191.5 0.0 4.5e-56 190.2 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase TPALS PF18178.1 KXZ56292.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Lipase_3 PF01764.25 KXZ56293.1 - 2e-10 40.7 0.0 3.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Methyltransf_8 PF05148.15 KXZ56294.1 - 3.7e-62 210.0 0.0 4.6e-57 193.4 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase AhpC-TSA PF00578.21 KXZ56294.1 - 1.3e-38 131.7 0.0 2.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ56294.1 - 5.2e-14 52.2 0.0 9.7e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXZ56294.1 - 2.9e-11 43.0 0.3 6.9e-11 41.8 0.3 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Fes1 PF08609.10 KXZ56294.1 - 6.1e-08 33.4 0.4 6.1e-08 33.4 0.4 3.6 4 0 0 4 4 4 1 Nucleotide exchange factor Fes1 Methyltransf_11 PF08241.12 KXZ56294.1 - 9.4e-07 29.4 0.0 2.3e-05 24.9 0.0 3.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ56294.1 - 0.011 16.5 0.1 0.24 12.1 0.0 2.8 1 1 1 2 2 2 0 Methyltransferase domain DUF2046 PF09755.9 KXZ56296.1 - 0.0019 17.5 18.6 0.019 14.2 3.7 3.3 2 1 1 3 3 3 2 Uncharacterized conserved protein H4 (DUF2046) Fez1 PF06818.15 KXZ56296.1 - 0.0056 17.1 26.9 0.84 10.0 4.2 3.1 1 1 2 3 3 3 3 Fez1 JIP_LZII PF16471.5 KXZ56296.1 - 0.023 14.8 5.4 0.071 13.3 0.8 3.5 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF4709 PF15821.5 KXZ56296.1 - 0.086 13.1 0.6 0.086 13.1 0.6 3.2 4 1 0 4 4 3 0 Domain of unknown function (DUF4709) DUF4407 PF14362.6 KXZ56296.1 - 0.12 11.7 41.5 1.3 8.3 18.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 KXZ56296.1 - 0.16 12.3 2.6 20 5.6 0.1 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family CCDC144C PF14915.6 KXZ56296.1 - 0.24 10.5 27.9 1.2 8.2 2.3 3.3 1 1 1 3 3 3 0 CCDC144C protein coiled-coil region DUF724 PF05266.14 KXZ56296.1 - 0.89 9.4 22.0 0.9 9.3 5.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 KXZ56296.1 - 1.9 5.9 36.0 2.8 5.3 36.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) hDGE_amylase PF14701.6 KXZ56296.1 - 2.2 7.2 5.8 1 8.4 3.4 1.5 1 1 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain PRKG1_interact PF15898.5 KXZ56296.1 - 2.5 9.1 27.1 0.41 11.6 5.9 3.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Troponin PF00992.20 KXZ56296.1 - 2.6 8.4 17.0 3.2 8.0 7.8 3.1 1 1 1 2 2 2 0 Troponin Jnk-SapK_ap_N PF09744.9 KXZ56296.1 - 2.8 8.1 30.3 0.39 10.9 10.4 3.1 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.12 KXZ56296.1 - 3.1 8.3 12.2 8.9 6.9 1.2 4.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4472 PF14739.6 KXZ56296.1 - 3.2 8.5 26.3 0.51 11.1 6.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) DUF1664 PF07889.12 KXZ56296.1 - 3.4 7.7 20.3 3.6 7.6 2.3 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) ApoO PF09769.9 KXZ56296.1 - 5.7 6.9 9.4 25 4.9 0.3 3.4 2 1 0 2 2 2 0 Apolipoprotein O GAS PF13851.6 KXZ56296.1 - 8.2 5.7 27.5 0.24 10.7 8.2 2.9 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KXZ56296.1 - 9.2 5.7 37.9 1.3 8.5 8.0 4.5 3 2 1 4 4 4 0 Intermediate filament protein DUF3381 PF11861.8 KXZ56297.1 - 0.05 13.4 9.8 0.093 12.5 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) eIF3_subunit PF08597.10 KXZ56297.1 - 0.083 12.8 11.1 0.12 12.2 10.6 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit ATP-synt_DE PF00401.20 KXZ56298.1 - 0.011 15.9 1.2 0.017 15.3 1.2 1.2 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ACPS PF01648.20 KXZ56299.1 - 2e-09 37.6 0.1 1.2e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily NIF PF03031.18 KXZ56300.1 - 6.4e-21 74.8 0.0 1.2e-11 44.7 0.0 2.4 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase NIF PF03031.18 KXZ56301.1 - 3.1e-35 121.2 0.0 4.1e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KXZ56301.1 - 0.00044 20.7 0.6 0.051 14.0 0.0 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXZ56301.1 - 0.0022 18.3 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_3 PF13640.6 KXZ56302.1 - 6.8e-10 39.7 0.0 1.2e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 KXZ56303.1 - 8.3e-06 26.3 2.3 0.0068 17.0 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ56303.1 - 0.0035 17.9 6.4 1.2 9.8 0.1 5.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ56303.1 - 0.059 13.7 0.1 0.53 10.7 0.1 2.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF2670 PF10875.8 KXZ56304.1 - 0.041 14.0 0.2 0.099 12.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2670) Kinesin PF00225.23 KXZ56305.1 - 1.8e-56 191.5 0.0 4.5e-32 111.3 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KXZ56305.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding bZIP_2 PF07716.15 KXZ56305.1 - 0.097 12.8 0.2 0.097 12.8 0.2 4.3 4 0 0 4 4 4 0 Basic region leucine zipper SlyX PF04102.12 KXZ56305.1 - 0.12 13.0 0.1 0.12 13.0 0.1 5.6 7 0 0 7 7 7 0 SlyX bZIP_1 PF00170.21 KXZ56305.1 - 0.83 9.8 0.0 0.83 9.8 0.0 3.4 4 0 0 4 4 4 0 bZIP transcription factor bVLRF1 PF18826.1 KXZ56307.1 - 3.9e-43 146.9 0.2 3.9e-43 146.9 0.2 2.0 2 1 1 3 3 3 1 bacteroidetes VLRF1 release factor Ank_4 PF13637.6 KXZ56307.1 - 7.8e-05 23.2 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ56307.1 - 0.00035 21.1 0.0 0.00094 19.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ56307.1 - 0.003 17.9 0.0 0.0065 16.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXZ56307.1 - 0.033 14.7 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 KXZ56307.1 - 0.037 14.6 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Glutaredoxin PF00462.24 KXZ56308.1 - 2.4e-16 59.7 0.0 3.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF656 PF04920.12 KXZ56308.1 - 0.033 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF656) DAGK_cat PF00781.24 KXZ56309.1 - 3.1e-19 68.8 0.0 5.8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 KXZ56309.1 - 6.2e-19 68.9 0.1 1.4e-11 45.0 0.0 3.1 1 1 2 3 3 3 2 Diacylglycerol kinase accessory domain DUF3419 PF11899.8 KXZ56310.1 - 1.8e-121 406.0 0.0 2.4e-121 405.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KXZ56310.1 - 8e-12 45.3 0.0 6.2e-11 42.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXZ56310.1 - 2.4e-09 37.8 0.2 5.8e-08 33.3 0.0 2.9 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ56310.1 - 5.4e-08 33.4 0.0 1.9e-06 28.4 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXZ56310.1 - 4.5e-07 30.5 0.1 3.5e-06 27.7 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXZ56310.1 - 4.6e-07 29.4 0.0 1.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXZ56310.1 - 1.3e-05 25.0 0.0 5.8e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXZ56310.1 - 2.4e-05 24.2 0.0 0.0016 18.2 0.0 2.8 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cullin PF00888.22 KXZ56311.1 - 5.9e-209 695.7 8.1 2.7e-164 548.2 9.3 2.1 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 KXZ56311.1 - 9.3e-27 92.9 1.9 1.8e-26 92.0 0.8 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 KXZ56311.1 - 0.0016 18.8 0.1 0.021 15.2 0.0 2.9 2 0 0 2 2 2 1 Penicillinase repressor HTH_IclR PF09339.10 KXZ56311.1 - 0.0089 15.8 0.0 0.093 12.6 0.0 2.7 3 0 0 3 3 3 1 IclR helix-turn-helix domain TrmB PF01978.19 KXZ56311.1 - 0.023 14.6 0.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Enkurin PF13864.6 KXZ56311.1 - 0.3 11.6 8.7 4.1 7.9 0.1 3.9 4 0 0 4 4 4 0 Calmodulin-binding Nucleoporin_N PF08801.11 KXZ56312.1 - 0.0087 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Snf7 PF03357.21 KXZ56316.1 - 6e-07 29.2 6.4 6e-07 29.2 6.4 1.7 1 1 1 2 2 2 1 Snf7 CDC73_N PF16050.5 KXZ56316.1 - 0.069 12.5 1.0 0.077 12.3 1.0 1.0 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal DUF4400 PF14348.6 KXZ56316.1 - 0.13 11.7 0.1 0.15 11.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Tctex-1 PF03645.13 KXZ56316.1 - 0.17 12.1 0.1 0.2 11.9 0.1 1.2 1 0 0 1 1 1 0 Tctex-1 family Snf7 PF03357.21 KXZ56318.1 - 1.1e-19 70.7 10.7 1.3e-19 70.5 10.7 1.0 1 0 0 1 1 1 1 Snf7 DUF494 PF04361.13 KXZ56318.1 - 0.005 16.8 1.2 0.0059 16.5 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF494) PspA_IM30 PF04012.12 KXZ56318.1 - 0.026 14.1 9.2 0.03 13.9 9.2 1.1 1 0 0 1 1 1 0 PspA/IM30 family YlqD PF11068.8 KXZ56318.1 - 0.029 14.7 5.6 0.038 14.3 5.5 1.4 1 1 0 1 1 1 0 YlqD protein HTH_26 PF13443.6 KXZ56318.1 - 0.062 13.7 0.2 0.14 12.6 0.2 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain YqaH PF17448.2 KXZ56318.1 - 0.096 13.0 1.0 2 8.8 0.2 2.5 1 1 2 3 3 3 0 Uncharacterized YqaH-like Seryl_tRNA_N PF02403.22 KXZ56318.1 - 0.1 12.8 7.8 0.088 13.0 5.9 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RVT_N PF13655.6 KXZ56318.1 - 0.11 12.8 4.5 0.12 12.6 1.1 2.5 1 1 1 2 2 2 0 N-terminal domain of reverse transcriptase Atg14 PF10186.9 KXZ56318.1 - 2 7.4 6.2 2 7.4 6.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 K_channel_TID PF07941.11 KXZ56319.1 - 0.011 16.2 3.8 0.011 16.2 3.8 4.0 5 0 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain DUF4604 PF15377.6 KXZ56319.1 - 0.032 14.7 1.2 0.035 14.5 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Peptidase_M11 PF05548.11 KXZ56320.1 - 1.6e-07 30.8 0.1 1.7e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 DUF3954 PF13128.6 KXZ56320.1 - 0.086 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) Peptidase_M11 PF05548.11 KXZ56321.1 - 0.0016 17.7 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 2-Hacid_dh_C PF02826.19 KXZ56322.1 - 2.9e-54 183.1 0.0 4e-53 179.4 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXZ56322.1 - 5.2e-32 110.3 0.0 6.1e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 KXZ56322.1 - 1.9e-06 27.3 1.6 1.5e-05 24.4 1.6 2.1 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KXZ56322.1 - 0.0006 19.9 0.1 0.0013 18.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KXZ56322.1 - 0.001 19.3 0.1 0.0035 17.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding_2 PF13380.6 KXZ56322.1 - 0.007 16.9 0.1 0.014 15.9 0.1 1.4 1 0 0 1 1 1 1 CoA binding domain Pyr_redox_2 PF07992.14 KXZ56322.1 - 0.0074 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KXZ56322.1 - 0.01 15.4 0.0 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 KXZ56322.1 - 0.024 15.2 0.3 0.079 13.5 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_C PF02775.21 KXZ56322.1 - 0.044 13.6 1.7 6.8 6.5 0.1 2.8 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_zinc_N PF00107.26 KXZ56322.1 - 0.058 13.4 0.0 7.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase XdhC_C PF13478.6 KXZ56322.1 - 0.096 13.2 0.0 1.2 9.6 0.0 2.2 1 1 1 2 2 2 0 XdhC Rossmann domain ThiF PF00899.21 KXZ56322.1 - 0.66 9.3 2.3 1.8 7.9 2.3 1.7 1 0 0 1 1 1 0 ThiF family Semialdhyde_dh PF01118.24 KXZ56322.1 - 1.2 9.6 5.2 9.9 6.6 0.1 2.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Clat_adaptor_s PF01217.20 KXZ56323.1 - 1.4e-54 183.9 1.5 1.5e-54 183.8 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain p450 PF00067.22 KXZ56324.1 - 5.2e-06 25.5 0.0 1.6e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 bMG6 PF17962.1 KXZ56324.1 - 0.06 13.5 0.0 0.94 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 KHA PF11834.8 KXZ56325.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Gluconate_2-dh3 PF13618.6 KXZ56325.1 - 0.13 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 CAP_N PF01213.19 KXZ56327.1 - 6.4 6.2 7.2 14 5.1 7.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Epimerase PF01370.21 KXZ56329.1 - 1.7e-14 53.9 0.0 2.8e-14 53.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ56329.1 - 1.5e-07 30.7 0.0 4.4e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXZ56329.1 - 4.8e-06 26.6 0.1 0.00029 20.8 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXZ56329.1 - 1.2e-05 24.6 0.0 0.097 11.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXZ56329.1 - 0.003 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXZ56329.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXZ56329.1 - 0.22 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 KXZ56330.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase_Tyr PF07714.17 KXZ56331.1 - 5.3e-36 124.2 0.0 4.9e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ56331.1 - 4e-33 114.9 0.0 2.5e-29 102.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Lipase_3 PF01764.25 KXZ56332.1 - 4.8e-17 62.1 0.0 9.3e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KXZ56332.1 - 0.0012 19.1 0.3 0.0027 17.9 0.3 1.6 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KXZ56332.1 - 0.0046 16.7 0.1 0.0073 16.0 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KXZ56332.1 - 0.013 15.4 0.1 0.013 15.4 0.1 2.1 3 0 0 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXZ56332.1 - 0.016 14.5 1.0 0.029 13.6 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 CobN-Mg_chel PF02514.16 KXZ56333.1 - 0 1159.1 0.0 0 1158.8 0.0 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 KXZ56333.1 - 2.1e-44 151.5 0.4 3.7e-44 150.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) DUF1295 PF06966.12 KXZ56334.1 - 2.5e-42 145.0 6.9 3.8e-42 144.4 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXZ56334.1 - 0.0022 18.4 0.2 0.008 16.6 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXZ56334.1 - 0.048 14.1 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Phospholipid methyltransferase Iso_dh PF00180.20 KXZ56335.1 - 1.2e-123 412.7 0.0 1.4e-123 412.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PCNA_C PF02747.15 KXZ56336.1 - 8.4e-05 22.7 0.0 0.00016 21.8 0.0 1.4 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Pertactin PF03212.14 KXZ56336.1 - 0.097 12.6 0.3 0.8 9.7 0.0 2.5 3 1 0 3 3 3 0 Pertactin DNA_ligase_A_M PF01068.21 KXZ56337.1 - 9e-63 211.6 0.1 1.5e-62 210.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXZ56337.1 - 5.2e-43 147.4 0.0 1.1e-42 146.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXZ56337.1 - 9.3e-22 77.5 0.0 2.9e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXZ56337.1 - 4.6e-06 27.0 0.1 7.7e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KXZ56337.1 - 0.00071 19.4 0.0 0.076 12.8 0.0 2.9 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain GCFC PF07842.12 KXZ56338.1 - 2.7e-76 256.8 0.0 4.1e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 KXZ56338.1 - 6.4e-22 77.9 11.1 1.4e-21 76.8 11.1 1.5 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal G-patch PF01585.23 KXZ56338.1 - 3e-15 55.8 2.9 3e-15 55.8 2.9 2.5 2 1 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXZ56338.1 - 4.5e-05 23.4 1.9 4.5e-05 23.4 1.9 3.3 3 0 0 3 3 3 1 G-patch domain SWIRM-assoc_1 PF16495.5 KXZ56338.1 - 3 7.9 15.9 0.036 14.0 1.4 2.8 3 0 0 3 3 3 0 SWIRM-associated region 1 DUF2849 PF11011.8 KXZ56338.1 - 8 7.2 10.3 4.7 7.9 1.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) p450 PF00067.22 KXZ56339.1 - 8e-57 193.0 0.0 2.3e-40 138.7 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 Ribosomal_L24e PF01246.20 KXZ56340.1 - 5.1e-34 116.3 4.4 5.1e-34 116.3 4.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 KXZ56340.1 - 0.03 14.3 2.8 0.082 12.9 2.3 2.0 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FUSC PF04632.12 KXZ56340.1 - 0.74 8.3 1.4 0.95 7.9 1.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2175 PF09943.9 KXZ56340.1 - 1.3 9.3 9.0 0.43 10.9 1.4 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) SUIM_assoc PF16619.5 KXZ56340.1 - 1.3 9.1 9.4 0.17 12.0 4.9 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SBP PF03110.14 KXZ56344.1 - 9.9e-24 83.5 4.1 2e-23 82.5 4.1 1.5 1 0 0 1 1 1 1 SBP domain RNA_pol_Rpb1_1 PF04997.12 KXZ56345.1 - 6.8e-78 262.1 0.7 3.2e-40 138.4 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KXZ56345.1 - 1.5e-06 28.5 0.0 3.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 DUF4407 PF14362.6 KXZ56347.1 - 0.0028 17.0 9.6 0.0039 16.6 9.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF2052 PF09747.9 KXZ56347.1 - 0.26 11.4 18.1 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CPSF100_C PF13299.6 KXZ56347.1 - 0.49 10.5 7.9 0.29 11.3 4.2 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CENP_C_N PF15622.6 KXZ56347.1 - 0.65 9.4 6.2 0.98 8.8 6.2 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal SAPS PF04499.15 KXZ56347.1 - 0.72 8.6 1.9 0.96 8.2 1.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2828 PF11443.8 KXZ56347.1 - 2.6 6.0 9.4 4.2 5.3 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3987 PF13148.6 KXZ56347.1 - 5.4 5.9 16.2 12 4.8 16.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4604 PF15377.6 KXZ56347.1 - 5.5 7.4 28.0 2.9 8.3 14.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) His_Phos_1 PF00300.22 KXZ56348.1 - 8.6e-20 71.2 0.2 4.3e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF4071 PF13281.6 KXZ56348.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) PP2C PF00481.21 KXZ56350.1 - 2.1e-32 112.8 0.0 2.4e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Ank_2 PF12796.7 KXZ56351.1 - 3.4e-13 50.0 0.0 1.9e-07 31.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ56351.1 - 3.8e-11 43.3 0.1 1.9e-06 28.3 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ56351.1 - 1.7e-10 41.0 0.2 8.1e-05 22.8 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ56351.1 - 2.1e-08 34.2 1.8 0.00025 21.3 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXZ56351.1 - 5.5e-07 29.4 0.2 0.043 14.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Y_phosphatase3 PF13350.6 KXZ56352.1 - 1.8e-36 126.3 0.0 1.4e-27 97.2 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family SOG2 PF10428.9 KXZ56352.1 - 0.8 8.8 4.6 1 8.5 4.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apolipoprotein PF01442.18 KXZ56353.1 - 1e-05 25.5 16.1 1.3e-05 25.2 16.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1451 PF07295.11 KXZ56353.1 - 0.015 15.3 14.1 0.039 14.0 3.8 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF1664 PF07889.12 KXZ56353.1 - 0.15 12.1 2.5 0.24 11.5 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PIN_8 PF18476.1 KXZ56353.1 - 0.24 11.3 3.1 0.32 10.8 3.1 1.3 1 0 0 1 1 1 0 PIN like domain DUF842 PF05811.13 KXZ56353.1 - 0.3 10.8 6.4 0.44 10.2 6.4 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Phage_min_cap2 PF06152.11 KXZ56353.1 - 0.35 9.7 10.4 0.48 9.3 10.4 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 AAA_13 PF13166.6 KXZ56353.1 - 0.46 9.1 5.8 0.6 8.7 5.8 1.2 1 0 0 1 1 1 0 AAA domain Mitofilin PF09731.9 KXZ56353.1 - 0.49 9.2 21.2 0.53 9.1 21.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Baculo_PEP_C PF04513.12 KXZ56353.1 - 0.58 10.2 5.0 1.3 9.0 5.0 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3527 PF12043.8 KXZ56353.1 - 0.58 9.7 3.4 0.68 9.4 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Mis12 PF05859.12 KXZ56353.1 - 0.92 9.6 5.4 3.9 7.5 5.0 2.1 1 1 0 1 1 1 0 Mis12 protein DBINO PF13892.6 KXZ56353.1 - 1 9.7 9.4 1.2 9.5 9.4 1.1 1 0 0 1 1 1 0 DNA-binding domain BshC PF10079.9 KXZ56353.1 - 1.1 7.9 8.8 1.3 7.7 8.8 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC VSG_B PF13206.6 KXZ56353.1 - 1.2 8.3 21.8 1.4 8.1 21.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Sec23_helical PF04815.15 KXZ56353.1 - 1.5 8.7 5.2 5.1 7.0 5.2 1.9 1 1 0 1 1 1 0 Sec23/Sec24 helical domain DUF1993 PF09351.10 KXZ56353.1 - 2.2 8.4 11.8 2.6 8.2 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) FdhE PF04216.12 KXZ56353.1 - 3 7.7 19.7 3.6 7.4 19.7 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF4686 PF15742.5 KXZ56353.1 - 3.2 6.8 9.9 3.8 6.5 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF2150 PF09920.9 KXZ56353.1 - 4 7.4 14.1 4.9 7.1 14.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Lant_dehydr_C PF14028.6 KXZ56353.1 - 4.2 6.8 18.9 42 3.5 18.9 1.9 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term MAT1 PF06391.13 KXZ56353.1 - 4.8 7.0 6.2 6.8 6.5 6.2 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF1216 PF06746.11 KXZ56353.1 - 5.6 7.0 11.2 10 6.1 11.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1216) UPF0160 PF03690.13 KXZ56353.1 - 8.3 5.9 8.8 14 5.2 8.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0160) DUF3486 PF11985.8 KXZ56353.1 - 8.8 6.7 28.5 11 6.3 28.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) DUF4638 PF15472.6 KXZ56354.1 - 1.4 8.6 7.1 1.8 8.2 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Y_phosphatase3 PF13350.6 KXZ56355.1 - 1.3e-20 74.3 0.1 1.2e-16 61.5 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family TT_ORF2 PF02957.15 KXZ56356.1 - 0.071 14.0 0.6 0.19 12.7 0.6 1.7 1 0 0 1 1 1 0 TT viral ORF2 Sedlin_N PF04628.13 KXZ56357.1 - 8.3e-28 97.1 0.0 1e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXZ56357.1 - 9.5e-08 32.1 0.0 1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Nup35_RRM PF05172.13 KXZ56357.1 - 0.022 14.7 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TPP_enzyme_C PF02775.21 KXZ56358.1 - 8.8e-19 67.8 0.0 1.5e-18 67.1 0.0 1.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXZ56358.1 - 0.017 14.3 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Romo1 PF10247.9 KXZ56358.1 - 0.15 12.4 0.1 7.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 TPP_enzyme_N PF02776.18 KXZ56359.1 - 3.2e-31 108.3 0.1 4.3e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXZ56359.1 - 5.5e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXZ56360.1 - 4.5e-18 65.5 0.0 6.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXZ56360.1 - 0.084 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Romo1 PF10247.9 KXZ56360.1 - 0.15 12.5 0.0 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 HR1 PF02185.16 KXZ56361.1 - 0.046 13.9 2.2 2.3 8.4 0.2 2.1 1 1 1 2 2 2 0 Hr1 repeat BST2 PF16716.5 KXZ56361.1 - 0.062 13.9 2.4 0.084 13.5 2.4 1.1 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 SOGA PF11365.8 KXZ56361.1 - 0.067 14.3 0.9 0.094 13.9 0.9 1.2 1 0 0 1 1 1 0 Protein SOGA SlyX PF04102.12 KXZ56361.1 - 0.19 12.4 5.2 6.1 7.5 1.3 2.1 1 1 1 2 2 2 0 SlyX FlxA PF14282.6 KXZ56361.1 - 0.97 9.5 8.4 8.6 6.4 8.6 1.9 1 1 0 1 1 1 0 FlxA-like protein COX16 PF14138.6 KXZ56362.1 - 8.8e-09 35.8 0.0 1.2e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Glutenin_hmw PF03157.13 KXZ56363.1 - 0.0019 16.7 18.1 0.0026 16.3 18.1 1.1 1 0 0 1 1 1 1 High molecular weight glutenin subunit TFIIA PF03153.13 KXZ56363.1 - 0.0024 17.9 14.6 0.0027 17.8 14.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAN_4 PF14295.6 KXZ56363.1 - 0.0089 15.9 3.7 0.83 9.6 1.3 2.4 2 0 0 2 2 2 2 PAN domain Ndc1_Nup PF09531.10 KXZ56363.1 - 0.61 8.7 9.2 0.71 8.5 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 KXZ56363.1 - 0.99 8.0 6.4 1.1 7.8 6.4 1.1 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 KXZ56363.1 - 1 8.7 22.2 1.4 8.2 22.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.9 KXZ56363.1 - 7 5.4 24.4 9 5.0 24.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PIN_3 PF13470.6 KXZ56365.1 - 2.7 8.8 7.8 5.9 7.7 6.5 2.2 1 1 0 1 1 1 0 PIN domain ParE_toxin PF05016.15 KXZ56365.1 - 4.4 8.0 6.8 3.6 8.3 0.6 2.8 2 1 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE PSI_8 PF00796.18 KXZ56369.1 - 1.2e-11 44.2 6.6 2.6e-11 43.1 6.6 1.6 1 0 0 1 1 1 1 Photosystem I reaction centre subunit VIII Asparaginase_II PF06089.12 KXZ56369.1 - 0.25 10.3 4.3 0.32 10.0 4.3 1.1 1 0 0 1 1 1 0 L-asparaginase II SET PF00856.28 KXZ56370.1 - 2.5e-14 54.0 0.0 5.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXZ56370.1 - 0.00016 22.4 0.0 0.00054 20.7 0.0 1.9 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Pkinase PF00069.25 KXZ56373.1 - 8.7e-57 192.5 0.0 1.3e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56373.1 - 5e-45 153.8 0.0 7.9e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ56373.1 - 0.00066 18.6 0.0 0.0018 17.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXZ56373.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KinB_sensor PF16767.5 KXZ56373.1 - 0.016 15.6 0.1 0.048 14.1 0.1 1.8 1 1 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB ABC1 PF03109.16 KXZ56373.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC1 family GTP_EFTU PF00009.27 KXZ56374.1 - 3.3e-52 176.9 0.0 5.2e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KXZ56374.1 - 2.6e-49 165.8 0.1 4.6e-49 165.0 0.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KXZ56374.1 - 7.2e-22 77.2 0.1 2.4e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus RRM_1 PF00076.22 KXZ56374.1 - 2.6e-18 65.6 0.2 3.2e-17 62.1 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU_D2 PF03144.25 KXZ56374.1 - 6.2e-09 36.1 0.7 1.3e-08 35.1 0.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXZ56374.1 - 5e-06 26.6 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KXZ56374.1 - 1.8e-05 24.7 0.0 9e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KXZ56374.1 - 9.6e-05 22.2 0.0 0.00036 20.4 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 KXZ56374.1 - 0.0024 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KXZ56374.1 - 0.075 12.5 0.0 0.22 10.9 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit E1-E2_ATPase PF00122.20 KXZ56375.1 - 3.7e-45 153.7 1.6 3.1e-43 147.4 0.9 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KXZ56375.1 - 1.2e-18 68.2 0.3 3.3e-17 63.5 0.3 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXZ56375.1 - 5.6e-07 29.2 0.0 1.8e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXZ56375.1 - 0.0004 20.2 0.2 0.0044 16.8 0.1 2.6 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXZ56375.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) PDDEXK_6 PF04720.12 KXZ56376.1 - 2.4e-15 57.1 0.0 4.6e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 PDDEXK-like family of unknown function CDO_I PF05995.12 KXZ56377.1 - 0.0011 18.3 0.1 0.28 10.5 0.0 2.6 1 1 0 2 2 2 2 Cysteine dioxygenase type I Ribosomal_60s PF00428.19 KXZ56377.1 - 0.04 14.5 3.4 0.053 14.1 0.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein TctB PF07331.11 KXZ56378.1 - 0.0076 16.5 2.0 0.012 15.9 2.0 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Kinesin PF00225.23 KXZ56379.1 - 2.4e-80 270.0 0.0 2.4e-80 270.0 0.0 3.6 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ56379.1 - 1.9e-09 37.6 0.0 6.5e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Tropomyosin_1 PF12718.7 KXZ56379.1 - 0.0065 16.6 23.4 0.0065 16.6 23.4 8.0 1 1 4 7 7 7 2 Tropomyosin like ZapB PF06005.12 KXZ56379.1 - 0.0072 16.7 4.7 0.0072 16.7 4.7 13.4 3 3 6 9 9 9 1 Cell division protein ZapB LSM PF01423.22 KXZ56380.1 - 4.9e-20 71.0 0.0 5.9e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KXZ56380.1 - 0.016 15.3 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain SM-ATX PF14438.6 KXZ56380.1 - 0.13 12.4 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain ABC_tran PF00005.27 KXZ56381.1 - 2.1e-22 80.1 0.0 4.4e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXZ56381.1 - 7.4e-08 32.6 0.0 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ56381.1 - 2.1e-06 27.3 0.1 0.004 16.6 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 KXZ56381.1 - 0.00063 20.2 0.3 0.0055 17.1 0.3 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXZ56381.1 - 0.0074 16.2 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KXZ56381.1 - 0.0077 16.5 0.0 0.014 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXZ56381.1 - 0.021 15.0 0.0 0.029 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXZ56381.1 - 0.024 14.4 0.3 0.055 13.2 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXZ56381.1 - 0.028 14.9 0.1 0.028 14.9 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXZ56381.1 - 0.031 14.0 0.0 0.49 10.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 KXZ56381.1 - 0.053 13.8 0.6 2.8 8.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXZ56381.1 - 0.075 12.7 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KXZ56381.1 - 0.081 12.6 0.1 0.27 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXZ56381.1 - 0.095 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXZ56381.1 - 0.13 11.6 1.1 0.61 9.4 0.3 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXZ56381.1 - 0.14 12.1 1.4 0.61 10.1 0.3 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXZ56381.1 - 0.16 12.0 0.0 2.4 8.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Pyrophosphatase PF00719.19 KXZ56383.1 - 2.4e-32 112.0 0.0 3.6e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pkinase PF00069.25 KXZ56384.1 - 1.2e-61 208.4 0.0 1.6e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56384.1 - 3.3e-28 98.7 0.0 4.8e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 KXZ56384.1 - 5.9e-12 44.3 21.0 0.00045 19.8 2.2 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif Kinase-like PF14531.6 KXZ56384.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KXZ56384.1 - 0.21 10.5 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain SHR3_chaperone PF08229.11 KXZ56385.1 - 0.12 11.3 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Abhydrolase_2 PF02230.16 KXZ56386.1 - 3.7e-49 167.5 0.0 4.3e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KXZ56386.1 - 3.2e-10 39.9 0.0 4.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXZ56386.1 - 2.1e-07 30.6 0.2 1.2e-05 24.9 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 KXZ56386.1 - 2.2e-07 30.8 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KXZ56386.1 - 1.6e-05 24.3 0.1 0.01 15.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ56386.1 - 0.0013 19.4 0.0 0.0014 19.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXZ56386.1 - 0.0018 18.1 0.1 0.093 12.6 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Cutinase PF01083.22 KXZ56386.1 - 0.0053 16.7 0.0 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.7 KXZ56386.1 - 0.0082 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXZ56386.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KXZ56386.1 - 0.035 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KXZ56386.1 - 0.061 13.0 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KXZ56386.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.3 1 1 0 1 1 1 0 Putative esterase DnaJ PF00226.31 KXZ56387.1 - 0.0012 19.0 0.1 0.002 18.2 0.1 1.7 1 1 0 1 1 1 1 DnaJ domain KIP1 PF07765.12 KXZ56387.1 - 0.011 15.8 0.3 5 7.3 0.1 2.1 2 0 0 2 2 2 0 KIP1-like protein MDMPI_N PF11716.8 KXZ56387.1 - 1.5 9.5 14.3 9.7 6.9 13.5 2.0 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain TMEM223 PF14640.6 KXZ56389.1 - 3.7e-05 24.0 0.0 9.1e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Transmembrane protein 223 Glyco_hydro_127 PF07944.12 KXZ56391.1 - 5.3e-77 259.5 0.0 3.2e-47 161.2 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 AbfB PF05270.13 KXZ56391.1 - 0.061 13.3 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B (ABFB) domain Glyco_hydro_127 PF07944.12 KXZ56392.1 - 9.1e-80 268.6 0.0 2.8e-55 187.8 0.2 2.4 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 AbfB PF05270.13 KXZ56392.1 - 8.6e-06 25.8 0.0 0.00011 22.2 0.0 2.6 2 1 1 3 3 3 2 Alpha-L-arabinofuranosidase B (ABFB) domain ShK PF01549.24 KXZ56392.1 - 0.13 12.8 6.2 0.23 12.0 6.2 1.4 1 0 0 1 1 1 0 ShK domain-like DEAD PF00270.29 KXZ56394.1 - 5.8e-15 55.5 0.0 9.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ56394.1 - 3.3e-07 30.6 0.0 6.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ56394.1 - 1.4e-06 28.4 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DJ-1_PfpI PF01965.24 KXZ56395.1 - 1.1e-12 48.0 0.0 8.3e-12 45.2 0.0 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXZ56395.1 - 4.3e-06 26.6 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like DUF3506 PF12014.8 KXZ56396.1 - 2.1e-18 66.7 0.0 4.4e-17 62.4 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) UVR PF02151.19 KXZ56396.1 - 0.14 11.9 8.2 0.21 11.4 0.8 2.6 2 0 0 2 2 2 0 UvrB/uvrC motif PAN_4 PF14295.6 KXZ56397.1 - 2e-05 24.4 10.6 0.00011 22.0 3.3 3.2 4 0 0 4 4 4 2 PAN domain PAN_1 PF00024.26 KXZ56397.1 - 0.00025 20.9 1.6 0.087 12.8 0.1 2.6 2 0 0 2 2 2 2 PAN domain Pkinase PF00069.25 KXZ56401.1 - 9.1e-70 235.0 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56401.1 - 6.3e-43 146.9 0.0 3e-42 144.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ56401.1 - 4.5e-05 22.9 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ56401.1 - 7.6e-05 22.7 0.1 0.00029 20.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ56401.1 - 0.0018 17.3 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KXZ56401.1 - 0.0021 17.7 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KXZ56401.1 - 0.013 14.3 0.0 0.035 12.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KXZ56401.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_3_Rpc31 PF11705.8 KXZ56402.1 - 0.046 14.0 8.8 1.5 9.0 1.2 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF5450 PF17529.2 KXZ56402.1 - 0.73 9.9 2.2 1.4 9.0 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5450) DUF4527 PF15030.6 KXZ56402.1 - 3.6 6.9 4.5 20 4.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) RNA_pol_3_Rpc31 PF11705.8 KXZ56403.1 - 0.25 11.6 1.2 0.33 11.2 1.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DPBB_1 PF03330.18 KXZ56404.1 - 1.4e-22 79.7 11.8 4.2e-09 36.6 0.0 4.6 3 2 2 5 5 5 4 Lytic transglycolase Lycopene_cycl PF05834.12 KXZ56404.1 - 0.2 10.6 0.0 25 3.8 0.0 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein DUF2556 PF10831.8 KXZ56404.1 - 0.7 9.9 7.8 98 3.0 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2556) Utp12 PF04003.12 KXZ56405.1 - 1.1e-05 25.7 0.0 3.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family ApbA_C PF08546.11 KXZ56408.1 - 9.3e-31 106.6 3.2 4.8e-30 104.3 3.2 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXZ56408.1 - 6.9e-19 68.0 0.1 3.4e-17 62.5 0.0 2.8 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KXZ56408.1 - 0.0078 16.2 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.6 KXZ56408.1 - 0.0099 16.1 0.0 0.04 14.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 KXZ56408.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXZ56408.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PG_binding_3 PF09374.10 KXZ56408.1 - 0.055 13.7 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 Predicted Peptidoglycan domain CDT1 PF08839.11 KXZ56409.1 - 5e-11 43.2 0.0 9.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 KXZ56409.1 - 9.9e-06 25.9 0.4 9.9e-06 25.9 0.4 2.2 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain DUF2993 PF11209.8 KXZ56410.1 - 2.7e-08 34.3 4.8 2.7e-08 34.3 4.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2993) zf-NF-X1 PF01422.17 KXZ56411.1 - 1.6e-06 28.0 63.2 7.2e-06 26.0 15.7 15.6 15 2 1 16 16 16 8 NF-X1 type zinc finger HU-CCDC81_euk_2 PF18289.1 KXZ56412.1 - 4.6e-13 49.1 0.0 1e-12 48.0 0.0 1.6 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 KXZ56412.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Ninjurin PF04923.12 KXZ56413.1 - 0.013 15.5 0.0 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 Ninjurin tRNA_anti-like PF12869.7 KXZ56413.1 - 0.15 11.7 0.2 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 tRNA_anti-like OAD_gamma PF04277.13 KXZ56413.1 - 0.2 12.3 4.0 0.81 10.3 0.2 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TctB PF07331.11 KXZ56413.1 - 0.31 11.3 11.6 5.1 7.4 11.9 2.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family ATG27 PF09451.10 KXZ56413.1 - 0.6 9.9 4.3 7.8 6.3 1.9 2.2 2 0 0 2 2 2 0 Autophagy-related protein 27 DUF3844 PF12955.7 KXZ56413.1 - 1.7 8.8 4.5 1.7 8.8 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3844) BT1 PF03092.16 KXZ56414.1 - 1.3e-60 205.1 14.3 5.3e-34 117.3 6.2 2.1 2 0 0 2 2 2 2 BT1 family HEAT_2 PF13646.6 KXZ56414.1 - 2.1e-09 37.7 25.2 0.0012 19.1 0.1 6.3 4 3 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KXZ56414.1 - 0.00019 21.4 31.0 0.63 10.5 0.1 10.3 10 0 0 10 10 10 2 HEAT repeat Cnd1 PF12717.7 KXZ56414.1 - 0.014 15.5 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXZ56414.1 - 0.088 13.4 0.0 19 6.0 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 KXZ56414.1 - 0.18 11.3 0.3 12 5.3 0.0 2.6 3 0 0 3 3 3 0 Tti2 family Dopey_N PF04118.14 KXZ56414.1 - 0.2 10.7 0.0 0.48 9.5 0.0 1.6 1 1 0 1 1 1 0 Dopey, N-terminal HEAT_EZ PF13513.6 KXZ56414.1 - 7.6 7.2 43.0 0.29 11.7 0.6 8.2 5 2 1 7 7 7 0 HEAT-like repeat GST_C_4 PF14834.6 KXZ56415.1 - 0.15 12.5 0.2 0.28 11.6 0.2 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2207 PF09972.9 KXZ56415.1 - 0.29 9.8 0.3 0.41 9.4 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 KXZ56415.1 - 0.55 10.1 2.0 1.2 9.1 2.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4834 PF16118.5 KXZ56415.1 - 2.9 8.9 3.6 14 6.7 3.6 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ABC_tran PF00005.27 KXZ56416.1 - 2.3e-21 76.8 0.0 3.4e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXZ56416.1 - 2.2e-13 50.2 10.4 3.4e-13 49.5 10.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 KXZ56416.1 - 3.1e-06 27.2 0.0 0.05 13.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ56416.1 - 0.0022 17.7 0.1 0.0055 16.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ56416.1 - 0.0049 17.3 0.4 0.017 15.5 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXZ56416.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF1184 PF06683.11 KXZ56416.1 - 0.039 13.4 0.2 0.073 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) SMC_N PF02463.19 KXZ56416.1 - 0.19 11.1 0.0 3.9 6.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KXZ56416.1 - 0.21 12.2 0.0 0.38 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KXZ56416.1 - 1.8 7.6 10.0 0.031 13.4 2.8 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein adh_short PF00106.25 KXZ56417.1 - 4.3e-18 65.5 0.0 1.4e-14 54.0 0.2 3.0 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXZ56417.1 - 1.8e-09 37.5 0.0 1.9e-07 30.9 0.0 2.7 1 1 2 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXZ56417.1 - 4.3e-09 36.5 0.4 7e-09 35.8 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXZ56417.1 - 0.0032 16.9 0.1 0.023 14.1 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KXZ56417.1 - 0.02 15.3 0.3 0.032 14.7 0.3 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXZ56417.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SBP_bac_8 PF13416.6 KXZ56419.1 - 1.1e-08 35.3 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Guanylate_cyc PF00211.20 KXZ56419.1 - 6.5e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SBP_bac_1 PF01547.25 KXZ56419.1 - 3.5e-05 23.9 0.1 6.3e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein RRM_1 PF00076.22 KXZ56420.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KXZ56421.1 - 2.4e-17 62.5 0.4 4.3e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MdcG PF10620.9 KXZ56421.1 - 0.0016 18.3 0.1 0.0034 17.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG ABC_membrane PF00664.23 KXZ56422.1 - 1e-05 25.4 0.7 1.3e-05 25.0 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXZ56422.1 - 0.061 13.8 0.0 0.75 10.3 0.0 2.1 1 1 0 1 1 1 0 ABC transporter A_deaminase PF00962.22 KXZ56423.1 - 1.8e-32 113.0 0.0 5.4e-32 111.4 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase MR_MLE_C PF13378.6 KXZ56423.1 - 0.26 10.8 2.8 1.9 8.0 2.0 2.2 1 1 1 2 2 2 0 Enolase C-terminal domain-like Arm PF00514.23 KXZ56425.1 - 1.3e-07 31.4 26.8 6.6e-06 26.0 0.3 7.3 7 1 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXZ56425.1 - 0.25 11.7 4.0 4.4 7.8 0.3 4.1 3 0 0 3 3 3 0 HEAT repeat PC4 PF02229.16 KXZ56426.1 - 4.6e-70 231.1 0.0 3.4e-18 65.0 0.0 4.2 4 0 0 4 4 4 4 Transcriptional Coactivator p15 (PC4) DEK_C PF08766.11 KXZ56426.1 - 1.8e-07 30.9 0.0 3.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain mTERF PF02536.14 KXZ56427.1 - 2.7e-08 33.1 0.0 1.8e-07 30.4 0.0 2.3 2 1 0 2 2 2 1 mTERF PALP PF00291.25 KXZ56428.1 - 1.1e-45 156.3 0.2 1.2e-45 156.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NleF_casp_inhib PF16809.5 KXZ56430.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 NleF caspase inhibitor DUF4795 PF16043.5 KXZ56431.1 - 0.00016 21.4 14.3 1.3 8.5 5.0 6.2 6 1 0 6 6 6 1 Domain of unknown function (DUF4795) SlyX PF04102.12 KXZ56431.1 - 0.0009 19.8 34.2 3.7 8.2 0.1 10.2 8 2 2 10 10 10 1 SlyX Sugarporin_N PF11471.8 KXZ56431.1 - 0.0029 17.5 22.2 0.11 12.4 1.5 3.9 2 1 1 3 3 3 2 Maltoporin periplasmic N-terminal extension NPR1_like_C PF12313.8 KXZ56431.1 - 0.021 14.3 0.5 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal Dynactin_p22 PF07426.11 KXZ56431.1 - 0.042 13.7 1.0 4.3 7.2 0.0 3.4 3 0 0 3 3 3 0 Dynactin subunit p22 Trimer_CC PF08954.11 KXZ56431.1 - 0.14 11.7 2.2 18 4.9 0.4 3.9 3 1 0 3 3 3 0 Trimerisation motif TSC22 PF01166.18 KXZ56431.1 - 0.2 12.0 6.4 23 5.4 0.3 5.1 6 0 0 6 6 6 0 TSC-22/dip/bun family Adaptin_binding PF10199.9 KXZ56431.1 - 0.23 12.1 10.7 77 3.9 0.5 4.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Baculo_PEP_C PF04513.12 KXZ56431.1 - 0.27 11.3 16.4 44 4.1 1.9 6.9 6 1 1 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 KXZ56431.1 - 0.41 10.8 8.0 21 5.3 0.0 6.8 7 1 2 9 9 9 0 Protein of unknown function (DUF2730) GIT_CC PF16559.5 KXZ56431.1 - 0.58 10.1 4.0 9.8 6.1 1.1 4.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor HSBP1 PF06825.12 KXZ56431.1 - 0.73 9.7 6.4 2.4 8.1 0.0 4.2 5 0 0 5 5 4 0 Heat shock factor binding protein 1 Tropomyosin_1 PF12718.7 KXZ56431.1 - 0.81 9.8 11.0 2.6 8.2 7.8 3.3 4 0 0 4 4 3 0 Tropomyosin like SPATA1_C PF15743.5 KXZ56431.1 - 1.3 9.1 4.3 7.4 6.6 2.0 3.3 4 1 1 5 5 3 0 Spermatogenesis-associated C-terminus CorA PF01544.18 KXZ56431.1 - 1.3 8.3 8.1 4 6.7 2.5 2.9 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein GAS PF13851.6 KXZ56431.1 - 1.7 8.0 9.7 14 5.0 7.3 3.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin PF00804.25 KXZ56431.1 - 2.5 7.8 5.3 1.1 8.9 1.2 2.6 2 0 0 2 2 2 0 Syntaxin Leu_zip PF15294.6 KXZ56431.1 - 2.9 7.4 10.2 0.59 9.6 4.6 2.6 2 1 0 3 3 3 0 Leucine zipper Cnn_1N PF07989.11 KXZ56431.1 - 3.4 7.9 6.1 3.2 8.0 1.4 3.5 3 0 0 3 3 2 0 Centrosomin N-terminal motif 1 Snapin_Pallidin PF14712.6 KXZ56431.1 - 4.4 7.8 10.4 61 4.1 2.7 5.1 5 0 0 5 5 5 0 Snapin/Pallidin SOGA PF11365.8 KXZ56431.1 - 6.4 8.0 8.8 40 5.4 0.0 4.6 5 1 0 5 5 4 0 Protein SOGA Csm1_N PF18504.1 KXZ56432.1 - 0.0037 17.6 1.4 0.015 15.6 0.3 2.2 2 0 0 2 2 2 1 Csm1 N-terminal domain LPG_synthase_TM PF03706.13 KXZ56432.1 - 0.02 14.5 0.1 0.02 14.5 0.1 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Leu_zip PF15294.6 KXZ56432.1 - 0.021 14.4 0.8 0.039 13.5 0.0 1.8 2 0 0 2 2 2 0 Leucine zipper CytochromB561_N PF09786.9 KXZ56432.1 - 0.043 12.8 0.0 0.14 11.1 0.0 1.6 1 1 0 2 2 2 0 Cytochrome B561, N terminal ATS3 PF06232.11 KXZ56432.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Embryo-specific protein 3, (ATS3) RskA PF10099.9 KXZ56432.1 - 0.097 13.0 11.3 9.9 6.4 12.0 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA NRBF2 PF08961.10 KXZ56432.1 - 0.11 12.1 1.2 0.19 11.3 0.7 1.6 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF2207 PF09972.9 KXZ56432.1 - 0.14 10.8 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC_tran_CTD PF16326.5 KXZ56432.1 - 0.42 10.9 4.9 0.67 10.3 1.9 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4179 PF13786.6 KXZ56432.1 - 2 8.9 3.9 20 5.8 0.2 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) APG6_N PF17675.1 KXZ56432.1 - 6.5 7.3 8.4 1.1 9.8 1.5 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region AAA_5 PF07728.14 KXZ56433.1 - 2.8e-45 153.7 0.0 7.6e-21 74.6 0.0 4.5 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_5 PF17865.1 KXZ56433.1 - 5.7e-29 100.3 0.0 1e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_7 PF12775.7 KXZ56433.1 - 1.7e-13 50.5 0.1 3.8e-05 23.3 0.1 3.4 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_3 PF07726.11 KXZ56433.1 - 8.4e-13 48.3 0.1 2.3e-06 27.5 0.0 4.6 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 KXZ56433.1 - 5.7e-12 45.8 0.0 1.3e-10 41.4 0.1 2.6 2 0 0 2 2 2 1 Midasin AAA lid domain AAA PF00004.29 KXZ56433.1 - 7.1e-12 45.9 0.1 0.016 15.6 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KXZ56433.1 - 8.4e-11 41.4 0.0 0.06 12.3 0.1 4.2 4 0 0 4 4 4 3 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 KXZ56433.1 - 8.5e-10 39.3 14.1 0.0039 17.6 0.0 4.8 4 1 0 4 4 3 3 AAA ATPase domain TsaE PF02367.17 KXZ56433.1 - 1.6e-09 37.8 1.8 0.12 12.3 0.1 3.4 3 0 0 3 3 3 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXZ56433.1 - 2.8e-09 37.3 0.3 0.0062 16.7 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 KXZ56433.1 - 3.2e-09 37.2 0.0 0.0096 16.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KXZ56433.1 - 1.4e-07 31.4 0.1 0.015 15.0 0.0 4.1 4 0 0 4 4 4 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KXZ56433.1 - 8e-07 28.6 4.0 0.16 11.3 0.1 5.2 5 1 0 5 5 5 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KXZ56433.1 - 8.3e-07 28.5 0.1 0.0028 16.9 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.6 KXZ56433.1 - 8.5e-07 28.6 0.2 0.015 15.0 0.1 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KXZ56433.1 - 9.8e-07 29.2 1.7 0.33 11.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 KXZ56433.1 - 1.9e-06 28.5 0.0 0.022 15.3 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 KXZ56433.1 - 2.1e-06 28.3 0.0 0.025 15.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KXZ56433.1 - 9e-06 24.9 0.2 0.11 11.6 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_25 PF13481.6 KXZ56433.1 - 1.7e-05 24.5 1.1 0.83 9.2 0.1 3.6 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KXZ56433.1 - 5.7e-05 23.1 0.7 0.73 9.7 0.0 4.0 4 0 0 4 4 4 1 NACHT domain AAA_14 PF13173.6 KXZ56433.1 - 6e-05 23.1 0.0 2.6 8.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 KXZ56433.1 - 0.0001 22.6 0.0 6.3 7.2 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.6 KXZ56433.1 - 0.00012 22.4 2.6 0.61 10.4 0.0 3.5 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 KXZ56433.1 - 0.00016 21.6 0.1 0.85 9.5 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase SRP54 PF00448.22 KXZ56433.1 - 0.00033 20.3 0.7 0.25 11.0 0.1 3.3 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_11 PF13086.6 KXZ56433.1 - 0.00045 20.1 0.1 1.6 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain Dynein_heavy PF03028.15 KXZ56433.1 - 0.00055 20.0 0.0 1.1 9.3 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Sigma54_activ_2 PF14532.6 KXZ56433.1 - 0.00066 19.8 0.2 0.35 11.0 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXZ56433.1 - 0.00095 18.9 0.2 8.7 6.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 KXZ56433.1 - 0.0012 18.5 1.2 0.62 9.6 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 KXZ56433.1 - 0.0012 18.6 0.4 11 5.7 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KXZ56433.1 - 0.0016 18.2 0.0 2 8.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KXZ56433.1 - 0.002 18.3 0.2 2.5 8.3 0.2 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KXZ56433.1 - 0.0036 17.0 12.4 0.067 12.9 0.0 4.1 4 1 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 KXZ56433.1 - 0.0085 16.2 0.1 8.3 6.5 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase Rad17 PF03215.15 KXZ56433.1 - 0.0094 15.9 0.1 4.1 7.3 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain PduV-EutP PF10662.9 KXZ56433.1 - 0.011 15.5 0.2 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 KXZ56433.1 - 0.035 14.0 0.0 0.33 10.8 0.0 2.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein SRPRB PF09439.10 KXZ56433.1 - 0.036 13.5 0.1 20 4.6 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 KXZ56433.1 - 0.043 14.3 0.2 6.8 7.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 KXZ56433.1 - 0.043 13.8 0.4 2.9 7.9 0.1 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 KXZ56433.1 - 0.05 12.8 0.1 20 4.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) TniB PF05621.11 KXZ56433.1 - 0.052 12.9 0.0 21 4.4 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein NTPase_1 PF03266.15 KXZ56433.1 - 0.06 13.3 0.8 12 5.8 0.1 2.6 3 0 0 3 3 2 0 NTPase DEAD PF00270.29 KXZ56433.1 - 0.075 12.8 0.0 8.8 6.1 0.1 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase dNK PF01712.19 KXZ56433.1 - 0.089 12.6 0.1 14 5.4 0.0 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase IPT PF01745.16 KXZ56433.1 - 0.11 11.9 0.1 16 4.8 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase ATPase_2 PF01637.18 KXZ56433.1 - 0.16 11.9 0.0 43 3.9 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea MobB PF03205.14 KXZ56433.1 - 0.18 11.7 0.7 20 5.1 0.1 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.16 KXZ56433.1 - 0.22 11.0 0.5 3.3 7.1 0.1 2.7 3 0 0 3 3 3 0 PhoH-like protein DLIC PF05783.11 KXZ56433.1 - 0.24 10.2 0.0 0.24 10.2 0.0 2.8 4 0 0 4 4 3 0 Dynein light intermediate chain (DLIC) UvrD-helicase PF00580.21 KXZ56433.1 - 0.27 10.7 0.2 20 4.6 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Bac_DnaA PF00308.18 KXZ56433.1 - 0.3 10.9 0.2 11 5.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein TRM PF02005.16 KXZ56434.1 - 6.3e-08 32.2 0.0 7.3e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF2067 PF09840.9 KXZ56434.1 - 0.0092 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) ADK PF00406.22 KXZ56435.1 - 5.8e-11 42.7 0.1 2.6e-10 40.6 0.1 2.2 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXZ56435.1 - 1e-06 29.2 0.0 3.4e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXZ56435.1 - 0.032 14.8 0.0 0.09 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXZ56435.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain TRM PF02005.16 KXZ56436.1 - 9e-23 81.0 0.0 1.1e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Bacillus_HBL PF05791.11 KXZ56437.1 - 0.01 15.7 0.6 0.01 15.7 0.6 4.8 4 1 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) Guanylate_cyc PF00211.20 KXZ56438.1 - 2.9e-16 59.6 0.0 2.2e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KXZ56440.1 - 7.6e-19 68.0 0.0 2e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CcmD PF04995.14 KXZ56440.1 - 0.089 12.9 2.4 0.25 11.5 2.4 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) LapA_dom PF06305.11 KXZ56440.1 - 0.47 10.3 1.8 1 9.2 1.8 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Guanylate_cyc PF00211.20 KXZ56441.1 - 2e-16 60.2 0.0 5.6e-08 32.6 0.0 3.2 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain PAH PF02671.21 KXZ56441.1 - 0.099 12.8 0.0 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Paired amphipathic helix repeat CcmD PF04995.14 KXZ56441.1 - 0.15 12.2 2.4 0.51 10.5 2.4 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) WSC PF01822.19 KXZ56442.1 - 1.1e-09 38.4 0.4 2e-09 37.5 0.4 1.4 1 0 0 1 1 1 1 WSC domain DEC-1_N PF04625.13 KXZ56443.1 - 0.39 9.7 5.6 0.59 9.1 5.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF3294 PF07957.11 KXZ56444.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) IBD PF10416.9 KXZ56444.1 - 0.043 13.8 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD Chlam_PMP PF02415.17 KXZ56446.1 - 2 9.0 21.2 0.64 10.6 1.2 4.7 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Y_phosphatase PF00102.27 KXZ56447.1 - 3.1e-10 40.0 0.1 4.8e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KXZ56447.1 - 2.5e-06 27.3 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KXZ56447.1 - 0.0037 17.0 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KXZ56447.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PAS PF00989.25 KXZ56448.1 - 1.3e-10 41.3 0.0 0.00012 22.1 0.0 3.8 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.10 KXZ56448.1 - 2.1e-10 40.8 0.0 0.051 13.8 0.0 4.7 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 KXZ56448.1 - 1.4e-09 38.2 0.0 3.2e-05 24.1 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 KXZ56448.1 - 0.03 14.3 0.0 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 PAS domain DLH PF01738.18 KXZ56450.1 - 8.8e-32 110.4 0.0 1.5e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family SET PF00856.28 KXZ56450.1 - 3.9e-09 37.1 0.0 1e-08 35.8 0.0 1.7 1 1 0 1 1 1 1 SET domain Abhydrolase_1 PF00561.20 KXZ56450.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TPR_5 PF12688.7 KXZ56450.1 - 0.098 12.9 0.6 0.2 11.9 0.6 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat Peptidase_S9 PF00326.21 KXZ56450.1 - 0.12 11.9 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 KXZ56450.1 - 0.18 11.7 0.3 2.3 8.1 0.1 2.5 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FAST_1 PF06743.15 KXZ56452.1 - 0.0052 16.7 0.2 24 5.0 0.1 5.0 5 1 1 6 6 6 2 FAST kinase-like protein, subdomain 1 Pkinase_Tyr PF07714.17 KXZ56453.1 - 3.4e-17 62.6 0.0 7.7e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56453.1 - 4.6e-15 55.7 0.0 1.9e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase PF00069.25 KXZ56454.1 - 7.2e-64 215.7 0.0 1.2e-63 214.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56454.1 - 5.4e-31 107.8 0.0 1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXZ56454.1 - 0.0011 18.0 0.1 0.0011 18.0 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXZ56454.1 - 0.039 13.3 0.3 0.092 12.1 0.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GrpB PF04229.14 KXZ56454.1 - 0.091 13.0 1.6 0.11 12.7 0.2 1.8 2 0 0 2 2 2 0 GrpB protein TFIIA PF03153.13 KXZ56454.1 - 2 8.3 21.1 3.6 7.5 21.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit S1 PF00575.23 KXZ56455.1 - 2.7e-31 107.7 3.8 1.5e-09 38.0 0.1 8.3 8 1 0 8 8 8 5 S1 RNA binding domain Suf PF05843.14 KXZ56455.1 - 1.7e-07 31.6 3.1 7.1e-07 29.5 0.0 3.1 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KXZ56455.1 - 1e-06 29.1 4.8 0.02 15.4 0.1 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ56455.1 - 0.0015 19.2 30.3 0.3 12.0 0.6 8.1 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 KXZ56455.1 - 0.015 14.6 6.9 0.085 12.0 4.2 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat CusF_Ec PF11604.8 KXZ56455.1 - 0.048 13.6 0.0 25 4.9 0.0 3.8 3 0 0 3 3 3 0 Copper binding periplasmic protein CusF TPR_6 PF13174.6 KXZ56455.1 - 0.16 12.7 0.1 0.16 12.7 0.1 6.2 7 1 0 7 7 7 0 Tetratricopeptide repeat TylF PF05711.11 KXZ56456.1 - 4.9e-51 173.5 0.0 6e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 KXZ56456.1 - 4.2e-06 27.7 0.0 6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TraE PF05309.11 KXZ56457.1 - 0.19 11.1 1.5 1 8.7 0.1 2.7 2 0 0 2 2 2 0 TraE protein FIST_C PF10442.9 KXZ56458.1 - 9.2e-21 74.2 0.3 2.2e-20 72.9 0.2 1.7 2 0 0 2 2 2 1 FIST C domain FIST PF08495.10 KXZ56458.1 - 2.5e-16 60.2 0.7 2.5e-16 60.2 0.7 2.0 2 1 0 2 2 2 1 FIST N domain Tctex-1 PF03645.13 KXZ56459.1 - 3.5e-26 91.4 0.5 4e-26 91.2 0.5 1.0 1 0 0 1 1 1 1 Tctex-1 family FtsJ PF01728.19 KXZ56460.1 - 2.8e-18 66.6 0.0 3.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 KXZ56460.1 - 4.2e-08 32.8 0.0 1.1e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 S4 domain Methyltransf_11 PF08241.12 KXZ56460.1 - 0.0035 18.0 0.0 0.0074 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Glycos_transf_3 PF00591.21 KXZ56461.1 - 1.8e-88 296.4 1.3 2.4e-88 296.0 1.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KXZ56461.1 - 1.6e-16 59.9 1.3 3.4e-16 58.8 1.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain ProRS-C_1 PF09180.11 KXZ56462.1 - 1.9e-26 92.0 0.4 5.7e-26 90.5 0.4 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KXZ56462.1 - 2.7e-18 65.9 0.0 5e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXZ56462.1 - 2.9e-18 66.5 0.0 4.7e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Cas3_C PF18395.1 KXZ56462.1 - 0.19 12.2 0.5 1.7 9.2 0.0 2.6 3 0 0 3 3 3 0 Cas3 C-terminal domain TT_ORF2 PF02957.15 KXZ56462.1 - 1.1 10.1 4.2 2.6 9.0 4.2 1.5 1 0 0 1 1 1 0 TT viral ORF2 XPG_N PF00752.17 KXZ56464.1 - 6.5e-30 103.6 0.0 1.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KXZ56464.1 - 1.4e-19 70.2 0.0 3.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region GIDA PF01134.22 KXZ56465.1 - 7.1e-154 512.6 0.0 8.8e-154 512.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KXZ56465.1 - 4.4e-68 229.6 0.0 6.1e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KXZ56465.1 - 4.8e-08 32.8 0.5 8.6e-08 31.9 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXZ56465.1 - 9.2e-07 28.4 0.9 1.6e-05 24.3 0.9 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXZ56465.1 - 1.2e-05 24.7 0.0 0.042 13.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXZ56465.1 - 4.8e-05 22.6 5.0 0.00021 20.5 1.6 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXZ56465.1 - 0.00064 19.4 11.6 0.012 15.2 0.2 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXZ56465.1 - 0.002 18.6 0.0 0.006 17.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXZ56465.1 - 0.0045 16.4 0.5 0.02 14.3 0.1 2.1 3 0 0 3 3 3 1 ThiF family HI0933_like PF03486.14 KXZ56465.1 - 0.0076 15.0 0.4 0.037 12.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KXZ56465.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KXZ56465.1 - 0.032 13.1 0.6 0.48 9.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase SLD5_C PF16922.5 KXZ56466.1 - 0.013 15.6 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus SLAIN PF15301.6 KXZ56466.1 - 0.027 13.8 0.2 0.048 12.9 0.2 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family Pkinase PF00069.25 KXZ56467.1 - 3.1e-61 207.1 0.0 4.5e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56467.1 - 2.2e-33 115.7 0.0 3.6e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KXZ56467.1 - 5.2e-11 42.5 0.2 0.00024 21.1 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KXZ56467.1 - 1.9e-07 30.7 0.0 4.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXZ56467.1 - 0.00017 21.3 0.1 0.00032 20.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 KXZ56467.1 - 0.0058 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KXZ56467.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ56467.1 - 0.02 14.8 0.0 0.096 12.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXZ56467.1 - 0.025 14.2 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PhyH PF05721.13 KXZ56468.1 - 4.7e-07 30.3 3.1 1.1e-06 29.1 0.0 2.8 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) TFIIA PF03153.13 KXZ56468.1 - 0.015 15.3 27.2 0.02 14.9 27.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ORC6 PF05460.13 KXZ56468.1 - 0.028 13.7 2.1 0.14 11.4 2.1 2.0 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Macoilin PF09726.9 KXZ56468.1 - 0.18 10.3 1.2 0.25 9.9 1.2 1.1 1 0 0 1 1 1 0 Macoilin family Phytochelatin PF05023.14 KXZ56469.1 - 1.7e-81 272.5 0.0 2.3e-80 268.8 0.0 2.1 1 1 0 1 1 1 1 Phytochelatin synthase DCA16 PF15349.6 KXZ56469.1 - 0.043 13.4 0.1 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 Peptidase_C39_2 PF13529.6 KXZ56469.1 - 0.084 13.4 0.0 0.29 11.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase_C39 like family Ribosomal_S16 PF00886.19 KXZ56470.1 - 1.9e-05 24.6 0.2 0.0002 21.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S16 TatD_DNase PF01026.21 KXZ56471.1 - 1.3e-36 126.3 0.0 1.9e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase DHHC PF01529.20 KXZ56471.1 - 1.7e-29 102.6 3.4 1.7e-29 102.6 3.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Amidohydro_2 PF04909.14 KXZ56471.1 - 4.8e-05 23.3 0.0 9.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase TPD PF14811.6 KXZ56472.1 - 3e-44 150.2 0.0 5.1e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif Glycos_transf_2 PF00535.26 KXZ56472.1 - 0.1 12.4 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Methyltrans_Mon PF14314.6 KXZ56472.1 - 0.29 9.1 0.0 0.42 8.6 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase Pkinase PF00069.25 KXZ56473.1 - 2.1e-14 53.6 0.0 2.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56473.1 - 4e-14 52.5 0.0 5.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3-RhoG_link PF16609.5 KXZ56473.1 - 0.046 13.5 0.1 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region DUF3292 PF11696.8 KXZ56473.1 - 0.23 9.8 1.1 0.3 9.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Transglut_core PF01841.19 KXZ56475.1 - 9.1e-13 48.6 0.2 1.5e-12 48.0 0.2 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core2 PF13369.6 KXZ56475.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily HALZ PF02183.18 KXZ56476.1 - 0.016 15.4 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 KXZ56476.1 - 0.3 11.3 0.0 0.45 10.7 0.0 1.1 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II UQ_con PF00179.26 KXZ56478.1 - 1e-39 135.4 0.0 1.4e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_4 PF13637.6 KXZ56480.1 - 8.6e-05 23.0 0.1 0.011 16.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ56480.1 - 0.0014 19.1 0.1 0.12 13.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ56480.1 - 0.024 15.0 1.4 0.39 11.1 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56480.1 - 0.073 13.7 0.7 21 6.1 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat ARID PF01388.21 KXZ56481.1 - 2.9e-13 50.3 0.0 4.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KXZ56481.1 - 8.8e-07 28.7 2.9 2.2e-06 27.5 2.9 1.7 1 0 0 1 1 1 1 PHD-finger HEM4 PF02602.15 KXZ56481.1 - 0.00061 19.2 0.1 0.0069 15.8 0.1 2.2 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD PHD_Oberon PF07227.11 KXZ56481.1 - 0.0028 17.6 1.9 0.0061 16.4 1.9 1.5 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein zf-HC5HC2H_2 PF13832.6 KXZ56481.1 - 0.15 12.2 0.9 0.28 11.3 0.9 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXZ56481.1 - 0.36 11.1 1.4 0.71 10.2 1.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 KXZ56481.1 - 3.8 7.5 7.7 0.31 11.0 1.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Pkinase_Tyr PF07714.17 KXZ56483.1 - 3.9e-27 95.1 0.0 1.7e-22 80.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56483.1 - 1.8e-26 93.1 0.0 3.6e-26 92.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ56483.1 - 0.002 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KXZ56484.1 - 1.6e-26 93.2 0.0 2.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56484.1 - 1.7e-26 93.1 0.0 5.8e-22 78.2 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ56484.1 - 0.0025 16.6 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXZ56486.1 - 7.7e-26 90.9 0.0 4e-20 72.2 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56486.1 - 2.8e-25 89.2 0.0 8.3e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ56486.1 - 0.0019 17.0 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXZ56486.1 - 0.03 14.2 0.1 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXZ56488.1 - 1.5e-30 106.4 0.0 3.7e-30 105.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56488.1 - 3.1e-30 105.3 0.0 2e-24 86.3 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ56488.1 - 0.0014 17.5 0.0 0.0026 16.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Phage-tail_3 PF13550.6 KXZ56488.1 - 0.0085 15.9 0.6 0.032 14.1 0.1 2.3 3 0 0 3 3 3 1 Putative phage tail protein APH PF01636.23 KXZ56488.1 - 0.099 12.5 5.2 0.36 10.7 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXZ56490.1 - 2.2e-29 102.5 0.0 7.5e-24 84.4 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56490.1 - 2.7e-28 99.1 0.0 6.7e-28 97.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KXZ56490.1 - 0.0072 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ank_4 PF13637.6 KXZ56491.1 - 0.0029 18.1 0.0 0.78 10.4 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56491.1 - 0.029 14.9 0.1 52 4.9 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat Pkinase PF00069.25 KXZ56493.1 - 1.8e-29 102.9 0.0 4e-29 101.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56493.1 - 2.2e-28 99.3 0.0 3.3e-23 82.3 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ56493.1 - 3.4e-05 22.8 0.0 5.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ56493.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TOM20_plant PF06552.12 KXZ56494.1 - 2e-19 70.1 0.0 2.3e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 KXZ56494.1 - 5.7e-06 25.9 0.0 1.7e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 KXZ56494.1 - 0.00013 22.4 0.5 0.019 15.5 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ56494.1 - 0.017 15.9 6.5 1.3 10.0 0.1 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ56494.1 - 0.034 14.3 5.2 3.7 7.9 0.1 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KXZ56494.1 - 0.15 12.1 0.7 11 6.1 0.1 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit TPR_10 PF13374.6 KXZ56494.1 - 4.3 7.3 8.9 4.8 7.2 2.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC1 PF03109.16 KXZ56495.1 - 0.00036 20.7 0.0 0.011 15.9 0.0 2.3 1 1 1 2 2 2 2 ABC1 family PAS_9 PF13426.7 KXZ56496.1 - 2.4e-10 40.6 0.0 5.5e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KXZ56496.1 - 4.7e-07 29.8 0.0 0.00029 20.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KXZ56496.1 - 9.6e-06 25.8 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KXZ56496.1 - 0.0062 16.5 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 1 PAS domain Ank PF00023.30 KXZ56497.1 - 0.00017 21.9 0.1 0.00017 21.9 0.1 4.0 5 1 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 KXZ56497.1 - 0.00089 19.5 0.1 0.023 15.2 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KXZ56497.1 - 0.0056 17.2 0.0 0.024 15.2 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ56497.1 - 0.16 12.4 1.1 2.4 8.6 0.1 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) SNF2_N PF00176.23 KXZ56498.1 - 2.1e-41 141.8 0.0 1.7e-40 138.8 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXZ56498.1 - 7e-15 55.3 0.0 1.4e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ56498.1 - 3e-08 33.8 0.0 5.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 KXZ56498.1 - 0.11 10.6 4.3 0.15 10.2 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2075 PF09848.9 KXZ56498.1 - 0.2 10.8 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_pol_3_Rpc31 PF11705.8 KXZ56498.1 - 0.22 11.7 5.9 0.42 10.8 5.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 KXZ56498.1 - 0.32 9.3 2.9 0.47 8.7 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Phasin_2 PF09361.10 KXZ56498.1 - 6 7.2 8.5 0.43 10.9 2.8 2.0 2 0 0 2 2 2 0 Phasin protein TFIIA PF03153.13 KXZ56498.1 - 6.5 6.6 7.5 1.8 8.5 1.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Uma2 PF05685.12 KXZ56499.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative restriction endonuclease RIO1 PF01163.22 KXZ56501.1 - 6.6e-47 159.5 0.0 1.2e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KXZ56501.1 - 1.1e-32 112.1 0.7 2.5e-32 110.9 0.4 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KXZ56501.1 - 3.3e-08 33.7 0.4 0.0018 18.2 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXZ56501.1 - 1.2e-07 31.3 0.2 0.004 16.5 0.0 2.7 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXZ56501.1 - 0.0019 17.6 0.2 0.098 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KXZ56501.1 - 0.02 14.2 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like PIP49_C PF12260.8 KXZ56501.1 - 0.099 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 NESP55 PF06390.12 KXZ56501.1 - 2.9 7.4 11.2 2.6 7.6 10.1 1.4 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) NUC153 PF08159.12 KXZ56503.1 - 2.5e-12 46.4 2.0 4.8e-12 45.5 2.0 1.5 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 KXZ56503.1 - 8.6e-05 22.8 0.0 0.00076 19.7 0.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXZ56503.1 - 0.59 11.1 2.9 1.5e+02 3.5 0.1 4.9 6 1 1 7 7 7 0 WD domain, G-beta repeat Hist_deacetyl PF00850.19 KXZ56504.1 - 3.6e-86 289.4 0.0 5.2e-86 288.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DUF4201 PF13870.6 KXZ56505.1 - 8.8e-45 152.6 27.4 8.8e-45 152.6 27.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) HrpB7 PF09486.10 KXZ56505.1 - 0.0061 17.0 2.6 0.0061 17.0 2.6 5.1 3 2 1 5 5 5 1 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 KXZ56505.1 - 0.016 15.5 46.4 0.022 15.0 16.9 4.1 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) KIP1 PF07765.12 KXZ56505.1 - 0.17 12.1 3.9 0.3 11.2 0.0 3.4 2 1 1 3 3 3 0 KIP1-like protein DUF3584 PF12128.8 KXZ56505.1 - 0.25 8.8 44.1 0.13 9.8 16.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 KXZ56505.1 - 0.56 10.7 61.7 0.65 10.5 14.6 4.9 1 1 3 4 4 4 0 Apg6 coiled-coil region FAM183 PF14886.6 KXZ56505.1 - 2.4 8.9 5.5 0.56 10.9 1.2 2.2 2 0 0 2 2 2 0 FAM183A and FAM183B related DUF334 PF03904.13 KXZ56505.1 - 5.5 6.5 15.7 0.34 10.4 9.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Hydrolase_4 PF12146.8 KXZ56506.1 - 1.4e-12 47.4 0.6 6.5e-09 35.4 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXZ56506.1 - 2.7e-09 38.0 0.2 1.3e-06 29.2 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 KXZ56506.1 - 1.5e-07 31.2 0.0 4.6e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXZ56506.1 - 1.9e-07 31.0 0.0 1.4e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXZ56506.1 - 2.1e-06 27.6 0.2 7.4e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXZ56506.1 - 6.3e-06 25.8 0.1 1.2e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXZ56506.1 - 7.6e-05 22.7 0.3 0.00022 21.1 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KXZ56506.1 - 8.7e-05 21.3 0.7 0.58 8.8 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KXZ56506.1 - 0.00018 21.5 0.1 0.071 13.0 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KXZ56506.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXZ56506.1 - 0.025 14.4 0.0 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KXZ56506.1 - 0.04 13.5 0.0 0.068 12.7 0.0 1.5 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 KXZ56506.1 - 0.11 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KXZ56506.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) 2OG-FeII_Oxy_3 PF13640.6 KXZ56507.1 - 2e-20 73.5 0.1 2.9e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2652 PF10851.8 KXZ56507.1 - 0.091 12.9 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) RAMP4 PF06624.12 KXZ56508.1 - 7.7e-21 73.9 0.8 8.4e-21 73.8 0.8 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1206 PF06724.11 KXZ56508.1 - 0.081 13.0 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Pkinase PF00069.25 KXZ56509.1 - 3.1e-34 118.5 0.0 8.4e-34 117.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56509.1 - 1.1e-32 113.4 0.0 6.1e-32 110.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KXZ56509.1 - 2.3e-22 79.0 3.5 7.5e-07 29.6 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ56509.1 - 2.3e-20 73.0 0.0 3.3e-09 37.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ56509.1 - 1.6e-19 69.7 0.4 5.5e-07 29.7 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56509.1 - 2.1e-16 58.3 0.3 7.4e-05 22.9 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KXZ56509.1 - 5.8e-13 48.6 2.4 0.00067 20.0 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat APH PF01636.23 KXZ56509.1 - 0.00069 19.6 0.7 0.00069 19.6 0.7 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Senescence_reg PF04520.13 KXZ56509.1 - 0.35 11.7 2.7 15 6.4 0.0 2.3 2 0 0 2 2 2 0 Senescence regulator Rrn6 PF10214.9 KXZ56509.1 - 4.1 5.8 5.2 5.8 5.3 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Katanin_con80 PF13925.6 KXZ56510.1 - 7.3e-33 113.9 0.0 1.2e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 KXZ56510.1 - 1.5e-30 104.7 10.1 1.5e-10 41.4 1.7 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56510.1 - 1.1e-14 54.5 0.1 0.0013 18.9 0.0 4.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXZ56510.1 - 2.8e-05 24.1 0.0 0.00088 19.2 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXZ56510.1 - 3.6e-05 22.9 0.0 0.0052 15.8 0.0 2.6 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXZ56510.1 - 0.028 13.1 0.1 0.52 8.9 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KXZ56510.1 - 0.037 12.6 0.1 3.9 5.9 0.0 2.1 1 1 0 2 2 2 0 Cytochrome D1 heme domain Lactonase PF10282.9 KXZ56510.1 - 0.077 12.2 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Nucleoporin_N PF08801.11 KXZ56510.1 - 0.1 11.3 0.1 0.95 8.1 0.1 1.9 1 1 1 2 2 2 0 Nup133 N terminal like tRNA-synt_2 PF00152.20 KXZ56511.1 - 6.8e-81 271.8 0.0 8.5e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXZ56511.1 - 8.8e-12 44.9 0.0 1.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXZ56511.1 - 6e-08 32.5 0.0 0.0047 16.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ank_2 PF12796.7 KXZ56512.1 - 3.7e-43 146.0 1.6 4e-07 30.5 0.0 6.5 5 1 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ56512.1 - 3.5e-36 123.1 9.4 1.4e-06 28.7 0.1 6.8 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ56512.1 - 9.2e-30 102.3 21.1 4.4e-06 26.9 0.1 9.5 5 4 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56512.1 - 2.4e-27 92.0 14.4 0.00091 19.5 0.0 10.5 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 KXZ56512.1 - 1.1e-24 85.7 21.3 0.0094 16.4 0.0 10.0 9 0 0 9 9 9 8 Ankyrin repeat Cation_efflux PF01545.21 KXZ56512.1 - 1.3e-23 83.7 6.8 2.2e-23 83.0 6.8 1.3 1 0 0 1 1 1 1 Cation efflux family Pkinase_Tyr PF07714.17 KXZ56512.1 - 2.9e-20 72.7 0.0 2.3e-09 37.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56512.1 - 7.4e-16 58.3 0.0 1.1e-07 31.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain ZT_dimer PF16916.5 KXZ56512.1 - 8.7e-07 29.0 1.8 2.3e-06 27.6 1.8 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Ank_2 PF12796.7 KXZ56513.1 - 4.7e-20 72.0 6.0 2.3e-09 37.7 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ56513.1 - 1.4e-12 47.9 2.4 9.6e-08 32.4 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ56513.1 - 3.8e-12 46.2 7.3 3.9e-06 27.0 0.3 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56513.1 - 1.2e-11 43.7 2.6 0.0092 16.4 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KXZ56513.1 - 2.7e-09 37.0 11.6 0.069 13.6 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Pkinase_Tyr PF07714.17 KXZ56514.1 - 2.6e-42 144.9 0.0 4e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ56514.1 - 2.4e-41 141.8 0.0 3.9e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KXZ56514.1 - 5.4e-15 55.7 0.0 2.5e-09 37.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ56514.1 - 2.1e-12 47.3 0.0 4.6e-08 33.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXZ56514.1 - 3.9e-12 46.1 0.1 1.3e-05 25.4 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56514.1 - 1e-11 43.9 0.3 0.00016 21.8 0.0 5.0 5 0 0 5 5 4 2 Ankyrin repeat Ank PF00023.30 KXZ56514.1 - 1.8e-11 43.9 1.7 0.0003 21.1 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Kinase-like PF14531.6 KXZ56514.1 - 0.0091 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXZ56514.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4946 PF16304.5 KXZ56514.1 - 0.018 14.8 0.1 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4946) Lectin_N PF03954.14 KXZ56514.1 - 0.15 11.8 0.7 0.44 10.3 0.7 1.8 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain APH PF01636.23 KXZ56514.1 - 0.16 11.9 0.0 0.16 11.9 0.0 4.2 2 1 1 3 3 2 0 Phosphotransferase enzyme family GAS PF13851.6 KXZ56514.1 - 2.8 7.2 30.0 0.33 10.3 6.2 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KXZ56514.1 - 10 5.4 26.0 79 2.4 25.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) His_Phos_2 PF00328.22 KXZ56516.1 - 7e-89 298.8 0.0 1.8e-45 155.9 0.0 3.3 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KXZ56516.1 - 2.7e-33 114.0 0.0 5.4e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KXZ56516.1 - 0.0032 17.1 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain FBPase PF00316.20 KXZ56517.1 - 7.2e-49 165.8 0.0 1.4e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Pkinase_Tyr PF07714.17 KXZ56518.1 - 1.6e-31 109.5 0.0 2.3e-24 86.1 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56518.1 - 3.2e-28 98.8 0.0 1.1e-18 67.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain cobW PF02492.19 KXZ56519.1 - 1.4e-39 135.5 0.0 2.1e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Methyltrans_RNA PF04452.14 KXZ56519.1 - 7.5e-19 68.0 0.0 1e-15 57.7 0.0 2.2 2 0 0 2 2 2 2 RNA methyltransferase CobW_C PF07683.14 KXZ56519.1 - 2e-09 37.3 0.1 6.6e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KXZ56519.1 - 0.00028 20.5 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain TsaE PF02367.17 KXZ56519.1 - 0.0069 16.4 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KXZ56519.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KXZ56519.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXZ56519.1 - 0.082 13.3 0.1 0.25 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KXZ56519.1 - 0.089 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KXZ56519.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KXZ56519.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KXZ56519.1 - 0.14 12.7 0.1 0.25 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXZ56519.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Exo_endo_phos PF03372.23 KXZ56520.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SRP-alpha_N PF04086.13 KXZ56521.1 - 10 6.0 20.0 2.6 7.9 10.2 2.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Glucodextran_B PF09136.10 KXZ56522.1 - 0.016 15.6 0.3 0.03 14.7 0.3 1.5 1 0 0 1 1 1 0 Glucodextranase, domain B ABC2_membrane PF01061.24 KXZ56523.1 - 3.1e-43 147.7 43.5 1.3e-34 119.5 22.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXZ56523.1 - 7.8e-16 58.8 0.0 1.2e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PDR_assoc PF08370.11 KXZ56523.1 - 2.1e-10 40.2 0.2 2.1e-10 40.2 0.2 3.9 3 1 1 4 4 4 1 Plant PDR ABC transporter associated AAA_21 PF13304.6 KXZ56523.1 - 2.1e-05 24.5 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXZ56523.1 - 0.00057 19.1 27.1 0.05 12.7 4.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KXZ56523.1 - 0.0032 17.4 0.3 0.0057 16.6 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KXZ56523.1 - 0.0041 16.8 1.0 0.012 15.3 1.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXZ56523.1 - 0.11 12.9 0.2 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 KXZ56523.1 - 0.21 11.0 0.2 17 4.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXZ56523.1 - 0.35 11.3 0.4 0.62 10.5 0.4 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXZ56523.1 - 0.44 10.2 2.5 1.2 8.8 2.5 1.8 1 1 0 1 1 1 0 AAA domain SR-25 PF10500.9 KXZ56524.1 - 0.0016 18.1 23.6 0.0016 18.1 23.6 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Glypican PF01153.19 KXZ56524.1 - 1.4 7.7 7.0 2.6 6.8 7.0 1.4 1 0 0 1 1 1 0 Glypican DUF3807 PF12720.7 KXZ56524.1 - 1.5 9.1 27.7 2.5 8.3 13.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SAP PF02037.27 KXZ56525.1 - 1.9e-13 49.8 0.9 3.4e-13 49.0 0.9 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KXZ56525.1 - 0.022 14.5 2.4 0.022 14.5 2.4 4.2 2 1 2 4 4 4 0 Tho1/MOS11 C-terminal domain TPR_1 PF00515.28 KXZ56527.1 - 8.5e-13 47.5 4.2 0.0009 19.0 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ56527.1 - 2e-10 39.9 7.8 0.0016 18.4 0.3 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ56527.1 - 6.3e-07 29.6 5.2 7.2e-06 26.2 0.7 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ56527.1 - 4.8e-05 23.2 2.5 0.00076 19.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ56527.1 - 0.00012 21.6 4.7 0.13 11.9 0.4 2.6 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 KXZ56527.1 - 0.0036 18.0 4.2 0.0036 18.0 4.2 4.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ56527.1 - 0.011 15.7 5.9 2.4 8.4 1.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 KXZ56527.1 - 0.022 14.5 2.2 0.037 13.7 2.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 KXZ56527.1 - 0.16 12.4 2.0 15 6.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ56527.1 - 0.72 10.4 15.3 0.76 10.3 2.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ56527.1 - 0.76 9.9 4.1 15 5.8 0.2 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat baeRF_family3 PF18845.1 KXZ56527.1 - 1.1 9.5 5.5 0.55 10.5 1.1 2.7 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 TPR_9 PF13371.6 KXZ56527.1 - 4.4 7.5 12.3 0.38 10.9 1.5 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ56527.1 - 6.8 6.7 7.7 5.5 7.0 1.6 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat vATP-synt_AC39 PF01992.16 KXZ56528.1 - 4.7e-109 364.9 3.8 5.3e-109 364.8 3.8 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DNA_pol_B_thumb PF14791.6 KXZ56529.1 - 6.4e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KXZ56529.1 - 5.7e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KXZ56529.1 - 8.2e-05 22.9 0.1 0.00023 21.4 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 KXZ56529.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm PAP_fibrillin PF04755.12 KXZ56530.1 - 9.7e-47 159.5 0.1 7.4e-15 55.4 0.1 4.3 3 2 0 3 3 3 3 PAP_fibrillin ApbE PF02424.15 KXZ56530.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 ApbE family Pkinase_Tyr PF07714.17 KXZ56531.1 - 1.4e-44 152.3 0.0 3.4e-39 134.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXZ56531.1 - 2.3e-38 132.1 0.0 3.5e-32 111.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KXZ56531.1 - 0.00046 19.1 0.0 0.00067 18.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXZ56531.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXZ56531.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3813 PF12758.7 KXZ56532.1 - 0.019 15.3 0.2 0.039 14.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) DUF3164 PF11363.8 KXZ56532.1 - 0.028 14.0 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) PRMT5 PF05185.16 KXZ56533.1 - 8.9e-66 221.0 0.0 1.3e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KXZ56533.1 - 7.7e-51 172.5 0.0 1.1e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 KXZ56533.1 - 1.2e-26 93.5 0.0 1.7e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Methyltransf_25 PF13649.6 KXZ56533.1 - 0.0001 22.9 0.0 0.0002 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ56533.1 - 0.013 16.1 0.0 0.028 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KXZ56533.1 - 0.029 14.1 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF4726 PF15855.5 KXZ56534.1 - 0.64 10.3 6.2 0.15 12.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Prok-JAB PF14464.6 KXZ56536.1 - 1.3e-10 41.1 0.1 3.1e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 KXZ56536.1 - 5e-10 39.4 0.0 8.1e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.31 KXZ56536.1 - 5.1e-10 39.4 0.1 1.1e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXZ56536.1 - 0.00074 19.7 0.2 0.0013 19.0 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXZ56536.1 - 0.037 13.9 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like DAP3 PF10236.9 KXZ56537.1 - 6.6e-16 58.4 0.0 1.2e-14 54.2 0.0 2.3 2 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KXZ56537.1 - 0.0045 17.4 8.1 0.02 15.2 8.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXZ56537.1 - 0.016 14.9 0.2 0.032 14.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXZ56537.1 - 0.034 14.4 0.1 0.067 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KXZ56537.1 - 0.036 14.0 0.2 0.62 10.0 0.1 2.3 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.9 KXZ56537.1 - 0.069 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Peptidase_M17_N PF02789.17 KXZ56537.1 - 0.36 10.7 5.3 0.4 10.5 1.7 2.5 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DnaB_bind PF10410.9 KXZ56537.1 - 0.78 10.0 4.5 17 5.7 0.1 2.4 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Mur_ligase_C PF02875.21 KXZ56538.1 - 0.00048 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain CDO_I PF05995.12 KXZ56539.1 - 1.1e-21 76.9 0.2 2.9e-17 62.5 0.2 2.5 2 1 0 2 2 2 2 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXZ56539.1 - 0.0041 16.6 0.0 0.014 14.9 0.0 1.8 1 1 1 2 2 2 1 PCO_ADO Pro_isomerase PF00160.21 KXZ56541.1 - 1.1e-07 32.2 0.0 4.6e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADH_zinc_N_2 PF13602.6 KXZ56542.1 - 5.2e-23 82.6 0.1 1e-22 81.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXZ56542.1 - 6.5e-13 48.8 0.2 1.6e-12 47.6 0.2 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXZ56542.1 - 0.0011 18.9 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXZ56542.1 - 0.21 11.0 2.3 0.17 11.3 0.5 1.8 2 0 0 2 2 2 0 short chain dehydrogenase zf-HC5HC2H PF13771.6 KXZ56543.1 - 6.4e-12 45.6 6.7 2.8e-11 43.5 6.3 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KXZ56543.1 - 1.2e-08 35.1 5.8 1.2e-08 35.1 5.8 2.0 1 1 1 2 2 2 1 PHD-zinc-finger like domain Homeodomain PF00046.29 KXZ56544.1 - 1e-06 28.5 0.1 1e-06 28.5 0.1 2.3 2 0 0 2 2 2 1 Homeodomain Caldesmon PF02029.15 KXZ56544.1 - 0.55 8.9 32.8 0.85 8.3 32.8 1.4 1 0 0 1 1 1 0 Caldesmon SMC_hinge PF06470.13 KXZ56545.1 - 1.4 9.3 5.1 1.1 9.6 1.3 2.0 1 1 1 2 2 2 0 SMC proteins Flexible Hinge Domain WSD PF15613.6 KXZ56546.1 - 3.8e-14 53.0 0.0 3.1e-13 50.0 0.0 2.1 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Cyclin_N PF00134.23 KXZ56547.1 - 4.1e-16 58.9 1.8 2.6e-15 56.3 1.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain START PF01852.19 KXZ56547.1 - 1.3e-05 24.7 0.6 2.9e-05 23.6 0.6 1.6 1 0 0 1 1 1 1 START domain Cyclin_C_2 PF16899.5 KXZ56547.1 - 0.051 14.0 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 Cyclin C-terminal domain TFIIB PF00382.19 KXZ56547.1 - 0.25 11.4 0.8 0.71 10.0 0.8 1.8 1 0 0 1 1 1 0 Transcription factor TFIIB repeat SAM_1 PF00536.30 KXZ56548.1 - 2.5e-12 47.0 0.0 5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXZ56548.1 - 1.8e-10 40.8 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KXZ56548.1 - 0.015 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF445 PF04286.12 KXZ56549.1 - 0.056 13.3 0.4 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Lipase_3 PF01764.25 KXZ56550.1 - 1.2e-11 44.7 0.0 3.5e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) POTRA PF07244.15 KXZ56551.1 - 7.1e-07 29.7 0.2 0.041 14.5 0.1 3.3 2 1 1 3 3 3 2 Surface antigen variable number repeat POTRA_2 PF08479.11 KXZ56551.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type DUF2683 PF10884.8 KXZ56551.1 - 0.3 11.4 1.1 1 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) GRP PF07172.11 KXZ56551.1 - 1 10.1 16.7 2.2 9.0 16.7 1.5 1 0 0 1 1 1 0 Glycine rich protein family SQS_PSY PF00494.19 KXZ56552.1 - 3e-41 141.7 0.5 4.5e-41 141.1 0.1 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase Adaptin_binding PF10199.9 KXZ56553.1 - 2.3e-09 37.9 7.0 2.8e-09 37.6 7.0 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 SUIM_assoc PF16619.5 KXZ56553.1 - 0.00053 20.0 1.5 0.00088 19.3 1.5 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 AAA_16 PF13191.6 KXZ56553.1 - 0.0012 19.2 4.9 0.0043 17.4 4.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXZ56553.1 - 0.029 14.4 0.4 0.051 13.7 0.3 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase WDCP PF15390.6 KXZ56553.1 - 0.16 10.4 0.7 0.17 10.2 0.7 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3381 PF11861.8 KXZ56553.1 - 1.7 8.4 8.8 2.2 8.0 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) LCE PF14672.6 KXZ56556.1 - 9.7 6.9 9.2 22 5.8 0.1 3.4 4 0 0 4 4 4 0 Late cornified envelope Fasciclin PF02469.22 KXZ56559.1 - 1.5e-30 106.1 0.0 1.4e-15 57.6 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain PGI PF00342.19 KXZ56560.1 - 4.7e-207 688.4 0.0 5.3e-207 688.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF5513 PF17632.2 KXZ56561.1 - 0.044 14.2 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5513) TspO_MBR PF03073.15 KXZ56562.1 - 4.7e-29 101.2 19.0 5.8e-29 100.9 19.0 1.0 1 0 0 1 1 1 1 TspO/MBR family DNase-RNase PF02577.14 KXZ56564.1 - 1.5e-15 57.0 0.0 2.2e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Bifunctional nuclease VHL PF01847.16 KXZ56564.1 - 1.7e-10 40.6 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 VHL beta domain Aldo_ket_red PF00248.21 KXZ56565.1 - 9.9e-45 153.0 0.0 2e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 Aldo/keto reductase family Kelch_4 PF13418.6 KXZ56566.1 - 1.4e-26 92.2 5.1 3.6e-11 42.9 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KXZ56566.1 - 1.2e-21 76.1 6.2 2.6e-07 30.1 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KXZ56566.1 - 3.7e-20 71.5 0.2 4.4e-06 26.8 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KXZ56566.1 - 1.1e-16 60.4 2.4 2.5e-06 27.3 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KXZ56566.1 - 2e-13 50.2 20.0 3.6e-07 30.3 0.2 6.8 7 1 1 8 8 8 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KXZ56566.1 - 5.8e-13 48.3 3.1 0.012 15.5 0.0 4.7 4 0 0 4 4 4 4 Kelch motif LRR_4 PF12799.7 KXZ56567.1 - 7.5e-12 45.3 0.2 0.018 15.4 0.0 5.7 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ56567.1 - 4.8e-11 42.2 6.5 0.0019 17.9 0.0 5.1 5 0 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 KXZ56567.1 - 2.4e-05 24.3 4.0 22 6.1 0.0 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KXZ56567.1 - 0.009 16.0 1.6 52 4.3 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat PALP PF00291.25 KXZ56568.1 - 4.4e-30 105.1 2.9 5.6e-30 104.8 2.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_5 PF00266.19 KXZ56568.1 - 0.023 13.7 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Actin PF00022.19 KXZ56569.1 - 5.9e-114 380.8 0.0 7.4e-113 377.2 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXZ56569.1 - 0.026 13.4 0.0 3.1 6.5 0.0 2.4 2 1 0 2 2 2 0 MreB/Mbl protein PDDEXK_6 PF04720.12 KXZ56570.1 - 1.2e-10 41.8 0.0 2.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 PDDEXK-like family of unknown function TgMIC1 PF11476.8 KXZ56571.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 RecO_N_2 PF13114.6 KXZ56571.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 RecO N terminal LepA_C PF06421.12 KXZ56572.1 - 6.6e-42 142.0 0.2 7.6e-42 141.8 0.2 1.0 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus MukE PF04288.13 KXZ56572.1 - 0.091 11.7 0.3 0.11 11.4 0.3 1.2 1 0 0 1 1 1 0 MukE-like family Kinesin PF00225.23 KXZ56573.1 - 6.2e-60 202.9 2.4 8e-60 202.5 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ56573.1 - 1.4e-09 38.0 0.0 3.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Phos_pyr_kin PF08543.12 KXZ56574.1 - 1.4e-15 57.4 0.0 2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXZ56574.1 - 1.9e-07 30.7 0.1 5.4e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase FIST PF08495.10 KXZ56575.1 - 9.4e-15 55.0 0.5 6.2e-14 52.4 0.1 2.2 2 0 0 2 2 2 1 FIST N domain FIST_C PF10442.9 KXZ56575.1 - 0.1 12.6 0.3 18 5.3 0.1 2.4 2 0 0 2 2 2 0 FIST C domain S100PBPR PF15427.6 KXZ56575.1 - 0.35 10.1 0.2 0.51 9.6 0.2 1.1 1 0 0 1 1 1 0 S100P-binding protein zf-C3HC4_3 PF13920.6 KXZ56576.1 - 9.6e-17 60.6 12.2 1.7e-16 59.8 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXZ56576.1 - 4.8e-07 29.5 13.1 9e-07 28.7 13.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ56576.1 - 2.6e-06 27.7 14.7 2.6e-06 27.7 14.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXZ56576.1 - 0.002 18.1 13.8 0.004 17.1 13.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Kazal_1 PF00050.21 KXZ56576.1 - 0.041 13.9 5.3 0.96 9.5 0.1 2.7 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain zf-C3HC4_2 PF13923.6 KXZ56576.1 - 0.086 12.7 15.7 0.18 11.7 15.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXZ56576.1 - 0.69 9.7 10.8 1.3 8.9 10.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ank_4 PF13637.6 KXZ56577.1 - 1.2e-21 76.8 1.3 3.1e-08 34.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ56577.1 - 5.5e-20 71.7 1.2 4.2e-19 68.9 0.5 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXZ56577.1 - 2.5e-19 69.1 4.1 2.3e-09 37.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXZ56577.1 - 1.4e-14 53.7 0.9 5.9e-06 26.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat STI1 PF17830.1 KXZ56577.1 - 1.2e-12 47.6 17.7 4e-08 33.1 0.1 4.4 2 1 1 3 3 3 2 STI1 domain Ank_3 PF13606.6 KXZ56577.1 - 5.8e-12 44.7 0.1 0.00052 20.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat GerD PF17898.1 KXZ56577.1 - 0.00015 21.7 7.3 0.017 15.1 1.8 2.7 3 0 0 3 3 3 2 Spore germination GerD central core domain XPC-binding PF09280.11 KXZ56577.1 - 0.19 11.5 1.8 12 5.7 0.0 3.3 3 0 0 3 3 3 0 XPC-binding domain Hist_deacetyl PF00850.19 KXZ56578.1 - 3e-65 220.7 0.2 2.7e-59 201.2 0.2 2.7 2 1 0 2 2 2 2 Histone deacetylase domain Roughex PF06020.11 KXZ56578.1 - 0.5 9.4 1.6 1 8.4 1.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Rieske PF00355.26 KXZ56579.1 - 4.8e-16 58.5 0.0 9.2e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ56579.1 - 2.1e-06 27.8 0.0 9e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Pheophorbide a oxygenase Rieske PF00355.26 KXZ56580.1 - 2.7e-34 117.0 0.0 1.1e-15 57.3 0.0 2.5 2 0 0 2 2 2 2 Rieske [2Fe-2S] domain PaO PF08417.12 KXZ56580.1 - 1.5e-14 53.9 0.0 1.9e-06 27.9 0.0 3.3 2 2 0 2 2 2 2 Pheophorbide a oxygenase CD20 PF04103.15 KXZ56580.1 - 0.016 15.3 0.2 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 CD20-like family NADH-G_4Fe-4S_3 PF10588.9 KXZ56580.1 - 0.17 11.4 1.4 17 5.0 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Lambda_CIII PF02061.16 KXZ56580.1 - 0.36 10.9 7.5 8.3 6.6 0.0 3.8 3 0 0 3 3 3 0 Lambda Phage CIII RecR PF02132.15 KXZ56580.1 - 3.1 7.4 4.5 34 4.1 0.4 2.5 2 0 0 2 2 2 0 RecR protein TPR_1 PF00515.28 KXZ56581.1 - 1.7e-13 49.7 4.6 1.5e-07 30.9 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ56581.1 - 7.4e-12 44.4 15.5 1.9e-08 33.8 0.6 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ56581.1 - 9e-12 45.4 12.6 9e-12 45.4 12.6 3.1 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ56581.1 - 6.4e-10 38.5 5.7 1.5e-09 37.4 1.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 KXZ56581.1 - 9e-08 32.2 9.8 9e-08 32.2 9.8 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ56581.1 - 3e-06 27.0 0.8 0.0038 17.3 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ56581.1 - 6.6e-06 26.5 16.2 0.00014 22.4 0.8 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ56581.1 - 8.7e-05 22.3 3.5 0.0079 16.2 0.2 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ56581.1 - 0.0001 22.4 2.3 0.0015 18.8 0.1 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ56581.1 - 0.00025 21.1 1.7 0.0088 16.1 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KXZ56581.1 - 0.00029 21.1 13.2 0.0076 16.5 1.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 KXZ56581.1 - 0.0004 20.4 1.0 0.0004 20.4 1.0 2.7 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KXZ56581.1 - 0.00065 20.2 7.3 0.00065 20.2 7.3 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ56581.1 - 0.048 13.9 1.5 0.048 13.9 1.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXZ56581.1 - 0.086 12.7 10.8 0.14 12.0 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ56581.1 - 0.29 11.9 3.8 0.94 10.3 0.1 3.3 4 1 0 4 4 3 0 Tetratricopeptide repeat UIM PF02809.20 KXZ56581.1 - 7.4 6.7 6.5 40 4.4 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif DUF3522 PF12036.8 KXZ56582.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Ceramidase PF05875.12 KXZ56582.1 - 0.021 14.2 1.1 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Ceramidase ubiquitin PF00240.23 KXZ56583.1 - 0.0012 18.5 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family PNISR PF15996.5 KXZ56583.1 - 0.0054 17.0 9.4 0.017 15.4 9.4 1.8 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR SDA1 PF05285.12 KXZ56583.1 - 1.2 8.5 9.9 2.9 7.2 9.9 1.5 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KXZ56583.1 - 1.2 8.4 5.6 2.1 7.6 5.6 1.3 1 0 0 1 1 1 0 NOA36 protein Spt20 PF12090.8 KXZ56583.1 - 6 6.4 11.4 0.21 11.2 2.6 2.5 2 0 0 2 2 2 0 Spt20 family PPP4R2 PF09184.11 KXZ56583.1 - 6.1 6.4 6.8 9.6 5.7 6.8 1.2 1 0 0 1 1 1 0 PPP4R2 zf-MYND PF01753.18 KXZ56585.1 - 7.2e-07 29.2 9.4 1.7e-06 28.0 9.4 1.7 1 0 0 1 1 1 1 MYND finger DKCLD PF08068.12 KXZ56588.1 - 5.1e-32 109.7 0.1 6.4e-31 106.2 0.2 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KXZ56588.1 - 7.1e-22 77.3 0.4 1.5e-21 76.3 0.4 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KXZ56588.1 - 2.8e-21 76.4 0.3 1.8e-18 67.3 0.3 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KXZ56588.1 - 1.5e-20 72.9 2.0 4.7e-20 71.3 2.0 1.9 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KXZ56588.1 - 0.032 14.5 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain DUF913 PF06025.12 KXZ56588.1 - 1.8 7.5 6.2 3.6 6.5 6.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 KXZ56588.1 - 7.6 5.2 10.5 10 4.7 10.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RILP PF11461.8 KXZ56589.1 - 0.0067 16.6 3.2 0.027 14.7 2.2 2.7 1 1 0 1 1 1 1 Rab interacting lysosomal protein DUF4140 PF13600.6 KXZ56589.1 - 0.0087 16.5 1.7 0.0087 16.5 1.7 8.2 4 2 2 6 6 6 1 N-terminal domain of unknown function (DUF4140) DUF5595 PF18077.1 KXZ56589.1 - 0.98 9.5 4.7 73 3.6 0.2 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5595) BicD PF09730.9 KXZ56589.1 - 4.6 5.6 45.3 0.25 9.7 2.7 4.1 3 1 1 4 4 4 0 Microtubule-associated protein Bicaudal-D Tubulin PF00091.25 KXZ56590.1 - 2e-65 220.7 0.0 2.6e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXZ56590.1 - 1.9e-23 83.0 0.0 2.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXZ56590.1 - 0.028 14.7 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain DUF3371 PF11851.8 KXZ56590.1 - 0.042 14.9 0.1 0.079 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Tubulin_3 PF14881.6 KXZ56590.1 - 0.051 13.3 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KXZ56590.1 - 0.091 11.9 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin like MMR_HSR1 PF01926.23 KXZ56592.1 - 4.8e-25 87.9 0.0 3.1e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 KXZ56592.1 - 4.9e-18 65.2 0.0 1.1e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 KXZ56592.1 - 5.1e-11 42.5 0.0 0.00031 20.4 0.1 3.5 3 0 0 3 3 3 3 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXZ56592.1 - 4.8e-07 29.4 0.0 9.4e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KXZ56592.1 - 2.3e-06 27.2 0.0 3.4e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family AIG1 PF04548.16 KXZ56592.1 - 4e-05 23.0 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KXZ56592.1 - 7.4e-05 22.9 0.0 0.008 16.3 0.0 3.1 2 1 1 3 3 3 1 Dynamin family MeaB PF03308.16 KXZ56592.1 - 0.00042 19.4 0.4 0.13 11.3 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KXZ56592.1 - 0.0014 18.6 0.2 2.3 8.1 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 KXZ56592.1 - 0.097 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 KXZ56592.1 - 0.14 12.4 0.0 17 5.6 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Mito_carr PF00153.27 KXZ56593.1 - 9.3e-38 128.1 13.3 2.8e-18 65.6 0.1 3.9 4 1 0 4 4 4 3 Mitochondrial carrier protein DUF3489 PF11994.8 KXZ56593.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) N_Asn_amidohyd PF14736.6 KXZ56594.1 - 3e-15 56.1 0.0 2.5e-06 26.8 0.0 2.6 3 0 0 3 3 3 2 Protein N-terminal asparagine amidohydrolase SeqA_N PF17206.3 KXZ56594.1 - 0.1 11.9 1.3 0.21 10.9 0.2 2.0 2 0 0 2 2 2 0 SeqA protein N-terminal domain DUF3172 PF11371.8 KXZ56596.1 - 1.5e-54 183.5 0.1 1.7e-54 183.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) PALP PF00291.25 KXZ56597.1 - 1.4e-52 178.9 4.0 2e-52 178.4 3.7 1.3 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme zf-CCCH PF00642.24 KXZ56598.1 - 1.8e-18 65.9 15.8 2.2e-09 37.0 3.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXZ56598.1 - 2.9e-13 49.3 10.6 5.2e-07 29.3 1.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXZ56598.1 - 1e-11 44.4 15.0 1.8e-06 27.8 3.4 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 KXZ56598.1 - 0.00041 20.7 5.9 0.2 12.2 0.4 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KXZ56598.1 - 0.068 13.9 10.0 0.27 11.9 1.9 2.4 1 1 1 2 2 2 0 Torus domain TPR_2 PF07719.17 KXZ56599.1 - 2.8e-06 27.0 5.2 8.3e-05 22.4 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ56599.1 - 3.9e-06 27.0 7.2 3.9e-06 27.0 7.2 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 KXZ56599.1 - 1.2e-05 25.0 10.4 2.5e-05 24.0 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXZ56599.1 - 1.8e-05 24.5 8.1 3.5e-05 23.6 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXZ56599.1 - 0.00031 20.6 4.9 0.0007 19.4 4.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TPR_1 PF00515.28 KXZ56599.1 - 0.00067 19.4 0.2 0.0039 16.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ56599.1 - 0.0062 16.4 1.1 0.0062 16.4 1.1 3.2 3 1 0 3 3 2 1 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KXZ56599.1 - 0.0064 16.3 7.0 0.012 15.4 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.6 KXZ56599.1 - 0.0084 16.3 0.7 0.065 13.5 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ56599.1 - 0.0089 15.7 0.5 0.035 13.8 0.5 2.1 1 0 0 1 1 1 1 TPR repeat zf-RING_UBOX PF13445.6 KXZ56599.1 - 0.02 14.9 7.8 0.043 13.9 7.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KXZ56599.1 - 0.045 13.7 9.9 0.094 12.7 9.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXZ56599.1 - 0.047 13.9 6.8 0.11 12.7 6.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXZ56599.1 - 0.072 13.2 3.9 0.14 12.3 3.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 TPR_21 PF09976.9 KXZ56599.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KXZ56599.1 - 0.12 13.1 0.2 0.12 13.1 0.2 6.3 6 0 0 6 6 3 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.14 KXZ56599.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C3H2C3 PF17122.5 KXZ56599.1 - 0.15 12.2 6.8 0.31 11.1 6.8 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 KXZ56599.1 - 0.63 10.4 10.3 1.6 9.1 10.3 1.7 1 0 0 1 1 1 0 Ring finger domain TPR_7 PF13176.6 KXZ56599.1 - 1.9 8.7 7.6 9.1 6.6 0.9 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 KXZ56599.1 - 2.1 8.3 7.6 5.3 7.0 7.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_14 PF13428.6 KXZ56599.1 - 3.1 8.9 19.8 0.55 11.2 1.8 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ56599.1 - 6.3 7.7 8.6 16 6.4 0.6 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CorA PF01544.18 KXZ56600.1 - 0.0059 16.0 4.2 0.008 15.5 4.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Band_7 PF01145.25 KXZ56600.1 - 0.017 15.1 2.2 0.017 15.1 2.2 2.7 3 1 0 3 3 2 0 SPFH domain / Band 7 family TolA_bind_tri PF16331.5 KXZ56600.1 - 0.031 14.3 6.4 0.031 14.3 6.4 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 KXZ56600.1 - 0.053 13.6 28.3 0.26 11.3 20.5 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1319 PF07028.11 KXZ56600.1 - 0.082 13.1 0.2 0.082 13.1 0.2 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF1319) CHDCT2 PF08074.11 KXZ56600.1 - 0.084 13.0 7.7 1.4 9.1 4.9 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain YabA PF06156.13 KXZ56600.1 - 0.1 13.2 14.4 0.34 11.6 0.6 2.9 2 1 1 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 KXZ56600.1 - 0.13 11.1 22.9 0.031 13.2 16.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Glyco_hydro_4 PF02056.16 KXZ56600.1 - 0.16 11.5 1.1 0.21 11.1 1.1 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Fib_alpha PF08702.10 KXZ56600.1 - 0.21 11.8 11.1 0.031 14.5 5.9 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KXZ56600.1 - 0.45 10.6 9.9 3.7 7.6 8.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 KXZ56600.1 - 0.48 10.2 13.5 0.063 13.1 7.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 KXZ56600.1 - 0.58 10.2 20.3 1.5 8.8 0.7 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.13 KXZ56600.1 - 0.64 10.2 14.5 5.3 7.2 0.3 3.6 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.11 KXZ56600.1 - 0.67 10.1 26.4 0.056 13.7 18.8 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 KXZ56600.1 - 0.74 8.8 17.4 0.073 12.1 11.4 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3573 PF12097.8 KXZ56600.1 - 0.86 8.4 2.8 0.76 8.5 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) LMBR1 PF04791.16 KXZ56600.1 - 1 8.2 3.3 1.1 8.1 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF812 PF05667.11 KXZ56600.1 - 1.4 7.7 17.1 2.8 6.7 17.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) T3SSipB PF16535.5 KXZ56600.1 - 1.9 8.9 26.3 0.26 11.8 22.1 1.7 2 0 0 2 2 1 0 Type III cell invasion protein SipB TMF_TATA_bd PF12325.8 KXZ56600.1 - 2.1 8.6 22.8 1.2 9.3 2.6 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Rotamase PF00639.21 KXZ56600.1 - 3.5 8.7 15.6 3.6 8.6 5.5 3.3 1 1 2 3 3 3 0 PPIC-type PPIASE domain ADIP PF11559.8 KXZ56600.1 - 3.6 7.6 27.1 1.2 9.2 17.4 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding XRN_M PF17846.1 KXZ56600.1 - 3.6 6.4 6.5 4.8 6.0 6.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain FliJ PF02050.16 KXZ56600.1 - 4.9 7.4 30.3 3.3 7.9 22.6 2.7 2 1 0 2 2 2 0 Flagellar FliJ protein FAM76 PF16046.5 KXZ56600.1 - 4.9 6.4 11.6 6.6 6.0 11.6 1.5 1 1 0 1 1 1 0 FAM76 protein PRCC PF10253.9 KXZ56600.1 - 6 7.6 14.8 10 6.8 14.8 1.4 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4407 PF14362.6 KXZ56600.1 - 7.6 5.8 24.9 14 4.9 24.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 KXZ56600.1 - 7.9 6.6 16.1 1.9 8.6 2.7 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.22 KXZ56600.1 - 8.1 6.7 17.1 8.4 6.7 7.7 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Methyltransf_25 PF13649.6 KXZ56601.1 - 1e-11 45.4 0.1 5.4e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXZ56601.1 - 2.4e-10 40.3 0.0 3.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXZ56601.1 - 7.9e-10 39.3 0.0 3e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXZ56601.1 - 1.7e-07 31.2 0.0 2.6e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXZ56601.1 - 5.8e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXZ56601.1 - 9.7e-06 24.7 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KXZ56601.1 - 3.1e-05 24.6 0.0 7.4e-05 23.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 KXZ56601.1 - 3.5e-05 23.4 0.1 5.4e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KXZ56601.1 - 3.8e-05 23.7 0.1 6.5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXZ56601.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KXZ56601.1 - 0.0048 16.7 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KXZ56601.1 - 0.0049 17.9 0.0 0.01 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KXZ56601.1 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KXZ56601.1 - 0.011 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KXZ56601.1 - 0.028 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.14 KXZ56601.1 - 0.029 13.8 0.9 0.36 10.2 0.2 2.4 1 1 0 2 2 2 0 Tellurite resistance protein TehB RrnaAD PF00398.20 KXZ56601.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AOX PF01786.17 KXZ56602.1 - 1.3e-25 90.2 0.7 1.9e-25 89.7 0.7 1.2 1 0 0 1 1 1 1 Alternative oxidase CTD_bind PF04818.13 KXZ56603.1 - 4.7e-05 24.1 0.0 7.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Filament PF00038.21 KXZ56604.1 - 0.001 18.7 6.2 0.001 18.7 6.2 3.2 2 1 1 3 3 3 1 Intermediate filament protein DUF4686 PF15742.5 KXZ56604.1 - 0.018 14.2 18.1 0.28 10.3 3.7 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4686) DUF4407 PF14362.6 KXZ56604.1 - 0.021 14.2 22.1 0.086 12.2 14.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 KXZ56604.1 - 0.035 14.4 12.0 0.52 10.7 0.1 4.6 5 0 0 5 5 5 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 KXZ56604.1 - 0.048 13.7 19.8 0.064 13.3 2.3 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 KXZ56604.1 - 0.054 14.1 18.1 0.082 13.5 0.0 5.3 6 0 0 6 6 6 0 SlyX bZIP_1 PF00170.21 KXZ56604.1 - 0.085 13.0 0.2 0.085 13.0 0.2 4.5 5 1 1 6 6 6 0 bZIP transcription factor Herpes_BLRF2 PF05812.12 KXZ56604.1 - 0.1 12.7 5.2 0.35 11.0 1.5 3.4 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein FPP PF05911.11 KXZ56604.1 - 0.11 10.6 13.4 0.054 11.7 2.8 2.4 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 KXZ56604.1 - 0.14 12.4 31.0 0.039 14.2 7.6 3.5 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) YabA PF06156.13 KXZ56604.1 - 0.16 12.6 9.7 1.9 9.2 1.1 3.5 3 1 0 3 3 3 0 Initiation control protein YabA BLOC1_2 PF10046.9 KXZ56604.1 - 0.16 12.3 14.2 2.1 8.7 0.6 4.4 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KXZ56604.1 - 0.16 12.1 7.4 8.3 6.6 0.8 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family PI3K_P85_iSH2 PF16454.5 KXZ56604.1 - 0.31 10.6 10.3 0.2 11.3 1.9 2.9 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HIP1_clath_bdg PF16515.5 KXZ56604.1 - 0.61 10.7 18.3 0.21 12.2 4.1 3.4 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 KXZ56604.1 - 0.62 10.2 19.8 0.68 10.0 2.6 3.9 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 KXZ56604.1 - 0.65 10.0 8.5 7.9 6.5 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF5401 PF17380.2 KXZ56604.1 - 1 7.3 13.6 0.043 11.9 7.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5401) PRKG1_interact PF15898.5 KXZ56604.1 - 1.3 10.0 16.6 10 7.1 4.2 3.6 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain Rootletin PF15035.6 KXZ56604.1 - 1.4 8.9 17.7 3.5 7.6 8.4 3.1 3 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Sipho_Gp157 PF05565.11 KXZ56604.1 - 1.8 8.6 16.3 0.2 11.6 7.0 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 SOGA PF11365.8 KXZ56604.1 - 2.2 9.5 16.1 0.61 11.3 0.9 3.8 3 2 1 4 4 4 0 Protein SOGA DUF4140 PF13600.6 KXZ56604.1 - 2.3 8.7 26.3 0.21 12.1 1.2 5.0 2 1 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) FIN1 PF17300.2 KXZ56604.1 - 3.3 7.1 6.3 10 5.5 0.2 2.3 2 0 0 2 2 2 0 Filaments in between nuclei protein-1 Not3 PF04065.15 KXZ56604.1 - 4.1 6.8 11.0 3.1 7.2 4.5 2.7 2 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF3138 PF11336.8 KXZ56604.1 - 4.3 5.8 14.7 1.2 7.7 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3138) Nsp1_C PF05064.13 KXZ56604.1 - 5.4 6.9 10.3 0.58 10.0 0.5 3.3 3 1 0 3 3 3 0 Nsp1-like C-terminal region FlaC_arch PF05377.11 KXZ56604.1 - 5.5 7.5 9.9 1.5 9.2 0.3 3.8 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) EzrA PF06160.12 KXZ56604.1 - 6.2 4.9 12.4 0.1 10.8 1.4 2.7 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA CPP1-like PF11833.8 KXZ56605.1 - 3.7e-06 26.7 3.4 2.8e-05 23.9 0.2 2.3 2 1 0 2 2 2 2 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DnaJ PF00226.31 KXZ56605.1 - 0.0036 17.4 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3042 PF11240.8 KXZ56605.1 - 0.32 11.0 2.2 0.81 9.8 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3042) FMN_dh PF01070.18 KXZ56607.1 - 2.6e-115 385.2 0.2 3.6e-115 384.7 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KXZ56607.1 - 1.7e-06 27.7 2.0 2.7e-06 27.0 2.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXZ56607.1 - 2.9e-06 26.6 0.2 6.5e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXZ56607.1 - 0.0003 20.0 0.3 0.0021 17.3 0.4 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase ThiG PF05690.14 KXZ56607.1 - 0.00084 18.7 0.5 0.0028 17.0 0.5 1.8 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KXZ56607.1 - 0.018 14.5 0.1 0.047 13.2 0.1 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 KXZ56607.1 - 0.038 13.2 0.1 0.094 11.9 0.0 1.6 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase SecY PF00344.20 KXZ56608.1 - 2.5e-74 250.3 12.5 3.3e-74 249.9 12.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KXZ56608.1 - 1.3e-17 63.3 0.1 1.3e-17 63.3 0.1 2.0 2 0 0 2 2 2 1 Plug domain of Sec61p Steroid_dh PF02544.16 KXZ56608.1 - 0.052 13.5 0.4 0.16 12.0 0.1 2.0 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Guanylate_cyc PF00211.20 KXZ56609.1 - 6.6e-53 179.1 0.0 1.1e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Radical_SAM PF04055.21 KXZ56611.1 - 4.5e-22 79.2 0.0 1.1e-21 78.0 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily HemN_C PF06969.16 KXZ56611.1 - 7.2e-05 22.8 0.1 0.00037 20.5 0.0 2.2 2 0 0 2 2 2 1 HemN C-terminal domain DUF2437 PF10370.9 KXZ56611.1 - 0.066 14.1 0.8 2.3 9.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) TMEM65 PF10507.9 KXZ56612.1 - 3.5e-38 129.9 0.6 9.3e-38 128.5 0.3 1.7 2 0 0 2 2 2 1 Transmembrane protein 65 EF-hand_6 PF13405.6 KXZ56612.1 - 0.073 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Sec7_N PF12783.7 KXZ56613.1 - 5.2e-21 75.2 0.0 1e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXZ56613.1 - 0.019 14.8 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) SPX PF03105.19 KXZ56613.1 - 0.39 10.6 1.9 34 4.2 0.0 3.0 3 1 0 3 3 3 0 SPX domain WD40 PF00400.32 KXZ56614.1 - 6.1e-10 39.5 0.8 0.028 15.3 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56614.1 - 1.3e-05 25.3 0.0 0.0048 17.2 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXZ56614.1 - 0.00033 19.7 0.1 0.072 12.0 0.0 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXZ56614.1 - 0.0083 16.0 0.0 4 7.5 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Pep_deformylase PF01327.21 KXZ56615.1 - 2.4e-22 79.2 0.0 3.4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Tfb4 PF03850.14 KXZ56616.1 - 1.2e-61 208.7 0.1 9.2e-61 205.7 0.1 1.9 1 1 0 1 1 1 1 Transcription factor Tfb4 PEPcase PF00311.17 KXZ56618.1 - 8.5e-42 143.2 0.0 9.4e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase adh_short_C2 PF13561.6 KXZ56619.1 - 2.7e-58 197.3 4.5 3e-58 197.1 4.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ56619.1 - 2.9e-49 167.2 4.4 3.6e-49 166.9 4.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ56619.1 - 5.8e-14 52.4 0.7 7.9e-14 52.0 0.7 1.1 1 0 0 1 1 1 1 KR domain WD40 PF00400.32 KXZ56621.1 - 6.4e-33 112.2 29.2 1.6e-05 25.6 0.1 12.4 12 2 0 12 12 12 7 WD domain, G-beta repeat Nup160 PF11715.8 KXZ56621.1 - 8.4e-10 37.9 1.3 0.019 13.6 0.1 4.6 5 0 0 5 5 5 3 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 KXZ56621.1 - 1e-09 38.7 0.1 4.2e-09 36.7 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KXZ56621.1 - 1.6e-08 33.5 0.1 0.00056 19.3 0.1 2.8 2 0 0 2 2 2 2 EF hand ANAPC4_WD40 PF12894.7 KXZ56621.1 - 2.2e-08 34.3 7.3 0.0057 16.9 0.0 6.9 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_6 PF13405.6 KXZ56621.1 - 1e-07 31.3 0.3 0.022 14.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KXZ56621.1 - 1.9e-05 24.4 0.3 4.8e-05 23.1 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXZ56621.1 - 4.1e-05 22.9 4.6 6.9e-05 22.2 0.1 2.8 3 0 0 3 3 3 1 EF hand Nucleoporin_N PF08801.11 KXZ56621.1 - 5.1e-05 22.2 0.0 1.4 7.6 0.0 3.7 4 0 0 4 4 4 3 Nup133 N terminal like SHIPPO-rpt PF07004.12 KXZ56623.1 - 1.6e-09 38.2 21.1 0.96 10.5 0.0 6.6 6 1 0 6 6 6 6 Sperm-tail PG-rich repeat DUF21 PF01595.20 KXZ56624.1 - 1.8e-34 118.9 0.1 2.3e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXZ56625.1 - 1.2e-05 25.7 1.4 0.14 12.6 0.1 3.3 3 0 0 3 3 3 3 CBS domain NAD_binding_4 PF07993.12 KXZ56626.1 - 6.4e-43 146.8 0.0 8.6e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXZ56626.1 - 5.4e-07 29.3 0.0 5.4e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXZ56626.1 - 0.0072 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KXZ56626.1 - 0.13 12.7 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXZ56627.1 - 4.7e-39 134.1 0.0 6.7e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXZ56627.1 - 4.3e-05 23.1 0.0 0.00012 21.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXZ56627.1 - 0.095 13.1 0.1 0.28 11.6 0.1 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SurE PF01975.17 KXZ56628.1 - 4.3e-35 121.3 0.2 4.3e-35 121.3 0.2 1.5 2 0 0 2 2 2 1 Survival protein SurE Ribosomal_L11_N PF03946.14 KXZ56629.1 - 2e-30 104.4 0.6 3.7e-30 103.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXZ56629.1 - 1.9e-24 85.9 2.7 1.9e-24 85.9 2.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Glyco_hydro_1 PF00232.18 KXZ56630.1 - 6.4e-61 206.1 1.3 3.2e-60 203.9 1.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 KXZ56630.1 - 3.4e-07 29.7 0.0 0.00092 18.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.24 KXZ56630.1 - 0.079 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Glyco_hydro_1 PF00232.18 KXZ56631.1 - 2.3e-62 210.9 5.4 9e-62 208.9 5.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 KXZ56631.1 - 2.2e-05 23.8 0.0 0.093 11.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 DUF563 PF04577.14 KXZ56632.1 - 6.9e-09 36.2 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DNTTIP1_dimer PF18192.1 KXZ56632.1 - 0.17 12.2 0.1 0.33 11.3 0.1 1.4 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain Rhodanese PF00581.20 KXZ56633.1 - 2.1e-15 57.1 0.0 3.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain S4 PF01479.25 KXZ56634.1 - 2.9e-13 49.3 0.0 7.4e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KXZ56634.1 - 3.5e-10 40.6 0.8 5.9e-10 39.9 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TTRAP PF14203.6 KXZ56634.1 - 0.0054 16.7 1.5 0.013 15.4 1.5 1.8 1 1 0 1 1 1 1 Putative tranposon-transfer assisting protein Glyco_hydro_16 PF00722.21 KXZ56635.1 - 5.7e-11 42.2 0.0 1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 KXZ56635.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) Chloroa_b-bind PF00504.21 KXZ56637.1 - 0.00021 21.9 7.2 0.0038 17.8 0.8 2.4 2 0 0 2 2 2 2 Chlorophyll A-B binding protein TPR_16 PF13432.6 KXZ56637.1 - 0.017 15.7 2.2 0.017 15.7 2.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PLA2_B PF01735.18 KXZ56638.1 - 1.5e-05 23.7 7.8 2.8e-05 22.7 7.5 1.6 2 0 0 2 2 2 1 Lysophospholipase catalytic domain Phage_GP20 PF06810.11 KXZ56639.1 - 0.047 13.5 0.7 14 5.5 0.0 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 PRKG1_interact PF15898.5 KXZ56639.1 - 0.062 14.2 1.0 0.062 14.2 1.0 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 KXZ56639.1 - 0.54 10.7 12.3 2.1 8.8 0.3 4.3 4 0 0 4 4 4 0 Cell division protein ZapB JIP_LZII PF16471.5 KXZ56639.1 - 0.84 9.8 8.5 8.8 6.6 0.6 3.9 4 1 0 4 4 4 0 JNK-interacting protein leucine zipper II NRBF2 PF08961.10 KXZ56639.1 - 1.4 8.5 6.6 0.94 9.0 1.4 2.6 3 0 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator PikAIV_N PF18605.1 KXZ56639.1 - 2.5 7.7 7.4 3.5 7.3 4.2 2.9 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain AHSP PF09236.10 KXZ56640.1 - 0.0061 17.0 0.5 0.0088 16.5 0.5 1.3 1 0 0 1 1 1 1 Alpha-haemoglobin stabilising protein Vps51 PF08700.11 KXZ56640.1 - 0.0072 16.4 1.6 0.011 15.8 1.6 1.5 1 1 0 1 1 1 1 Vps51/Vps67 Bap31_Bap29_C PF18035.1 KXZ56640.1 - 0.017 15.1 2.9 0.42 10.6 0.2 2.4 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4201 PF13870.6 KXZ56640.1 - 0.036 13.8 4.3 0.038 13.7 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 KXZ56640.1 - 0.077 11.9 5.3 0.092 11.6 5.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc42p PF11544.8 KXZ56640.1 - 0.16 12.0 3.0 1.3 9.1 0.2 2.1 1 1 1 2 2 2 0 Spindle pole body component Spc42p DUF3584 PF12128.8 KXZ56640.1 - 0.23 9.0 9.2 0.24 8.9 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Csm1_N PF18504.1 KXZ56640.1 - 0.3 11.5 5.7 1.3 9.4 0.0 2.3 2 1 0 2 2 2 0 Csm1 N-terminal domain OmpH PF03938.14 KXZ56640.1 - 1.4 9.3 9.9 1.6 9.1 9.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 KXZ56640.1 - 2.2 8.6 15.0 2.3 8.5 6.9 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4611 PF15387.6 KXZ56641.1 - 0.034 14.4 5.5 0.049 13.8 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF4473 PF14747.6 KXZ56641.1 - 0.039 14.5 0.0 0.071 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Cwf_Cwc_15 PF04889.12 KXZ56641.1 - 0.13 11.9 8.8 0.17 11.6 8.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 KXZ56641.1 - 0.41 10.2 6.9 1 8.9 7.3 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 KXZ56641.1 - 0.47 10.3 5.8 0.63 9.9 5.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 KXZ56641.1 - 1.2 8.4 8.1 1.4 8.2 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 KXZ56641.1 - 1.3 8.1 11.5 1.4 8.0 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Dicty_REP PF05086.12 KXZ56641.1 - 1.8 6.4 3.9 2.2 6.1 3.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3755 PF12579.8 KXZ56642.1 - 3.6e-08 32.9 0.6 3.6e-08 32.9 0.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3755) WD40 PF00400.32 KXZ56644.1 - 0.0004 21.1 1.6 0.16 12.9 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56644.1 - 0.00099 19.4 0.0 7.2 7.0 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S8 PF00082.22 KXZ56645.1 - 6.5e-27 94.6 0.0 1.4e-26 93.5 0.0 1.4 1 1 0 1 1 1 1 Subtilase family PA PF02225.22 KXZ56645.1 - 3.8e-05 23.6 0.1 0.00018 21.5 0.1 2.2 1 0 0 1 1 1 1 PA domain Copine PF07002.16 KXZ56647.1 - 2.1e-62 210.4 0.0 2.8e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 KXZ56647.1 - 1.7e-13 50.7 0.0 1.9e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KXZ56647.1 - 0.00039 20.6 0.0 0.00061 20.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2052 PF09747.9 KXZ56648.1 - 7.4e-33 114.3 22.3 4.6e-32 111.8 22.3 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Sporozoite_P67 PF05642.11 KXZ56648.1 - 0.058 11.5 0.7 0.081 11.0 0.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FlgM PF04316.13 KXZ56648.1 - 0.091 13.1 1.0 0.23 11.9 0.4 1.9 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM FAM176 PF14851.6 KXZ56648.1 - 0.26 10.9 3.7 0.61 9.7 3.7 1.6 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KXZ56648.1 - 5 7.6 11.1 0.99 9.8 6.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AOX PF01786.17 KXZ56650.1 - 8.6e-76 254.3 0.6 9.8e-76 254.1 0.6 1.0 1 0 0 1 1 1 1 Alternative oxidase SpoU_methylase PF00588.19 KXZ56653.1 - 5.3e-26 91.5 0.1 8.5e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF563 PF04577.14 KXZ56654.1 - 3e-10 40.6 0.0 4.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TatD_DNase PF01026.21 KXZ56655.1 - 1.1e-49 169.1 0.0 1.3e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase tRNA-synt_1e PF01406.19 KXZ56656.1 - 1.1e-118 396.1 0.4 2.7e-118 394.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KXZ56656.1 - 1.8e-05 23.7 0.3 0.0028 16.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KXZ56656.1 - 3.5e-05 24.2 0.1 3.5e-05 24.2 0.1 2.9 3 0 0 3 3 3 1 DALR domain tRNA-synt_1c PF00749.21 KXZ56656.1 - 0.0027 16.7 0.0 0.0057 15.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 KXZ56656.1 - 0.0039 16.2 0.0 0.4 9.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 KXZ56656.1 - 0.11 10.7 0.0 1.2 7.3 0.0 2.4 3 1 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) DUF4253 PF14062.6 KXZ56656.1 - 0.15 12.2 0.5 3.4 7.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) SAM_2 PF07647.17 KXZ56657.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) JmjC PF02373.22 KXZ56658.1 - 2.7e-40 137.3 0.1 4.1e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KXZ56658.1 - 3.1e-18 65.4 1.6 5.5e-18 64.6 1.6 1.4 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KXZ56658.1 - 3.9e-09 36.7 0.1 1e-08 35.4 0.1 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger Pkinase PF00069.25 KXZ56659.1 - 4.8e-63 213.0 0.0 5.5e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56659.1 - 4.9e-32 111.2 0.0 8.1e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ56659.1 - 7.9e-07 28.7 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ56659.1 - 3.4e-06 27.2 0.0 9.1e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXZ56659.1 - 2.3e-05 23.5 0.0 3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXZ56659.1 - 0.002 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXZ56659.1 - 0.009 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXZ56659.1 - 0.023 13.5 0.1 0.11 11.2 0.0 1.8 1 1 1 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KXZ56659.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 KXZ56659.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF2379 PF09543.10 KXZ56660.1 - 0.1 12.8 0.8 0.39 10.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) CCDC74_C PF14917.6 KXZ56660.1 - 0.12 12.9 0.1 0.18 12.3 0.1 1.2 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal GDP_Man_Dehyd PF16363.5 KXZ56661.1 - 1.2e-57 195.8 0.0 3.6e-57 194.2 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXZ56661.1 - 6.3e-49 166.6 0.0 8e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXZ56661.1 - 3.4e-12 46.0 0.0 4.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXZ56661.1 - 9e-12 44.7 0.0 4.7e-08 32.5 0.0 2.6 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXZ56661.1 - 9.1e-09 34.8 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXZ56661.1 - 1.8e-08 33.9 0.0 0.00011 21.4 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 KXZ56661.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KXZ56661.1 - 0.052 13.4 0.0 0.095 12.6 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 KXZ56661.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 KR domain ABC2_membrane PF01061.24 KXZ56662.1 - 2.2e-49 167.8 13.1 2.2e-49 167.8 13.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXZ56662.1 - 2.3e-19 70.3 0.0 3.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXZ56662.1 - 1.7e-08 34.0 10.9 2.6e-08 33.4 10.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KXZ56662.1 - 6e-05 22.5 2.9 0.00013 21.3 2.9 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXZ56662.1 - 0.0014 18.5 0.2 0.69 9.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXZ56662.1 - 0.053 13.4 0.2 0.092 12.6 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase RRM_1 PF00076.22 KXZ56663.1 - 4e-40 135.5 0.1 1.7e-13 50.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ56663.1 - 1.7e-06 28.1 0.0 1.3 9.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif AID PF18767.1 KXZ56663.1 - 0.0096 15.9 0.0 4.8 7.3 0.0 2.6 3 0 0 3 3 3 2 Activation induced deaminase RRM_5 PF13893.6 KXZ56663.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_8 PF13450.6 KXZ56664.1 - 8.4e-09 35.5 0.1 1.9e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXZ56664.1 - 1.7e-08 33.3 0.0 8.4e-08 31.1 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXZ56664.1 - 6.7e-07 28.8 0.2 9.9e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ56664.1 - 4.8e-05 23.8 0.3 9.2e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXZ56664.1 - 0.00012 21.6 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXZ56664.1 - 0.00019 21.1 3.1 0.00064 19.4 3.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXZ56664.1 - 0.0002 20.7 0.0 0.046 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXZ56664.1 - 0.00058 19.2 0.1 0.00085 18.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXZ56664.1 - 0.0009 18.6 1.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KXZ56664.1 - 0.0029 17.6 0.1 0.0065 16.5 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXZ56664.1 - 0.0033 16.8 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KXZ56664.1 - 0.0064 15.3 0.3 0.016 14.0 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KXZ56664.1 - 0.012 14.7 0.2 0.023 13.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KXZ56664.1 - 0.022 14.6 0.4 0.044 13.7 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ASFV_J13L PF05568.11 KXZ56664.1 - 0.042 13.6 0.7 0.057 13.2 0.7 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein IlvN PF07991.12 KXZ56664.1 - 0.047 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 KXZ56664.1 - 0.12 12.4 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 KXZ56664.1 - 0.15 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CHZ PF09649.10 KXZ56665.1 - 0.16 11.5 0.9 0.41 10.2 0.9 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ DUF4864 PF16156.5 KXZ56666.1 - 7.5e-10 39.4 0.0 1.2e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4864) FMO-like PF00743.19 KXZ56667.1 - 7.6e-09 34.5 0.0 8.8e-09 34.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXZ56667.1 - 0.0076 15.5 0.0 0.0081 15.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXZ56667.1 - 0.096 12.7 0.1 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXZ56668.1 - 0.007 16.6 0.1 0.017 15.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ASFV_J13L PF05568.11 KXZ56668.1 - 0.0093 15.7 0.2 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 African swine fever virus J13L protein FMO-like PF00743.19 KXZ56669.1 - 0.004 15.6 0.0 0.0051 15.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like ACCA PF03255.14 KXZ56669.1 - 0.2 11.5 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fasciclin PF02469.22 KXZ56670.1 - 1.7e-11 44.4 0.0 2.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Sel1 PF08238.12 KXZ56671.1 - 1.1e-07 32.3 1.3 0.008 16.8 0.0 4.3 4 0 0 4 4 4 2 Sel1 repeat TCP PF03634.13 KXZ56671.1 - 0.037 14.6 0.0 0.059 13.9 0.0 1.2 1 0 0 1 1 1 0 TCP family transcription factor zf-C3HC4_3 PF13920.6 KXZ56672.1 - 1.5e-11 44.0 9.8 2.2e-11 43.4 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GIDE PF12483.8 KXZ56672.1 - 1.1e-09 37.8 1.2 7.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 E3 Ubiquitin ligase Prok-RING_4 PF14447.6 KXZ56672.1 - 0.00024 20.9 11.2 0.00043 20.1 11.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXZ56672.1 - 0.023 15.0 11.6 0.04 14.3 11.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ56672.1 - 3.1 7.7 12.6 5.6 6.9 12.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 KXZ56673.1 - 1.5e-55 188.4 0.0 2.7e-55 187.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56673.1 - 7e-31 107.4 0.0 1.3e-30 106.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ56673.1 - 9.4e-08 31.7 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXZ56673.1 - 0.00016 21.7 0.0 0.65 9.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ56673.1 - 0.001 18.0 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Mo25 PF08569.11 KXZ56674.1 - 1.6e-118 395.8 4.6 1.9e-118 395.6 4.6 1.0 1 0 0 1 1 1 1 Mo25-like DUF2951 PF11166.8 KXZ56674.1 - 0.02 15.1 0.4 1.3 9.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) HEAT PF02985.22 KXZ56674.1 - 0.035 14.4 0.1 1.1 9.7 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat MOR2-PAG1_C PF14225.6 KXZ56674.1 - 0.041 13.7 3.3 0.27 11.1 3.1 2.1 1 1 1 2 2 2 0 Cell morphogenesis C-terminal V-ATPase_H_N PF03224.14 KXZ56674.1 - 0.05 12.9 3.1 0.051 12.9 1.5 1.8 2 0 0 2 2 2 0 V-ATPase subunit H HEAT_2 PF13646.6 KXZ56674.1 - 0.23 11.9 2.2 3.2 8.2 0.0 3.3 2 2 0 2 2 2 0 HEAT repeats RPAP1_C PF08620.10 KXZ56676.1 - 5.6e-11 42.4 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KXZ56676.1 - 6.1e-08 32.3 0.2 1.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 RPAP1-like, N-terminal HEAT PF02985.22 KXZ56676.1 - 1.3 9.4 5.2 3.2 8.2 0.5 2.8 2 0 0 2 2 2 0 HEAT repeat PCMT PF01135.19 KXZ56677.1 - 8.7e-25 87.7 0.0 1.5e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Hydrolase_6 PF13344.6 KXZ56678.1 - 5.9e-35 119.4 0.0 1e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ56678.1 - 1.1e-17 63.9 0.0 3.1e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXZ56678.1 - 5.4e-11 43.2 0.0 4.3e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXZ56678.1 - 2.4e-08 34.2 0.3 0.00017 21.7 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KXZ56678.1 - 0.0008 19.1 0.0 0.0022 17.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase DUF2608 PF11019.8 KXZ56678.1 - 0.0092 15.5 0.0 0.018 14.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) 5_nucleotid PF05761.14 KXZ56678.1 - 0.042 12.7 0.0 0.65 8.8 0.0 2.1 2 0 0 2 2 2 0 5' nucleotidase family Acid_phosphat_B PF03767.14 KXZ56678.1 - 0.05 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) NuA4 PF09340.10 KXZ56678.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Kinesin PF00225.23 KXZ56679.1 - 1.8e-55 188.2 0.0 1.4e-54 185.3 0.0 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXZ56679.1 - 2.5e-05 24.3 0.0 5.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding FlaC_arch PF05377.11 KXZ56679.1 - 0.0033 17.8 5.4 29 5.2 0.1 5.8 5 0 0 5 5 5 1 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 KXZ56679.1 - 0.27 11.1 6.0 0.04 13.8 0.6 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cpn60_TCP1 PF00118.24 KXZ56680.1 - 1.1e-151 505.9 4.1 1.2e-151 505.7 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PucR PF07905.11 KXZ56680.1 - 0.0064 16.8 0.1 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 Purine catabolism regulatory protein-like family DUF4598 PF15370.6 KXZ56681.1 - 7.4e-09 36.1 3.0 9.5e-09 35.7 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) DNA_pol_phi PF04931.13 KXZ56681.1 - 7 4.6 6.9 7.5 4.5 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KXZ56681.1 - 8.6 4.4 6.9 8.2 4.5 6.9 1.0 1 0 0 1 1 1 0 Nop14-like family Aa_trans PF01490.18 KXZ56682.1 - 4.6e-56 190.3 23.0 5.6e-56 190.0 23.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3087 PF11286.8 KXZ56682.1 - 0.0043 16.5 0.4 0.0043 16.5 0.4 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3087) CorA PF01544.18 KXZ56683.1 - 5.2e-10 39.1 4.2 6.4e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SfLAP PF11139.8 KXZ56683.1 - 0.0044 16.5 1.0 0.0079 15.7 0.5 1.6 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein DUF2207 PF09972.9 KXZ56683.1 - 0.078 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA_23 PF13476.6 KXZ56683.1 - 0.2 12.2 7.4 5.6 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NPV_P10 PF05531.12 KXZ56683.1 - 0.35 11.4 1.9 0.5 10.9 0.3 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 KXZ56683.1 - 1 9.2 3.9 5.1 7.0 0.1 2.6 3 0 0 3 3 3 0 Sec34-like family Ovate PF04844.13 KXZ56683.1 - 2.1 8.4 7.5 0.15 12.1 1.3 2.2 2 0 0 2 2 2 0 Transcriptional repressor, ovate DUF2721 PF11026.8 KXZ56683.1 - 7.3 6.5 11.0 1.6 8.6 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) FUSC PF04632.12 KXZ56683.1 - 8.1 4.8 14.4 0.38 9.2 2.9 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Pre-PUA PF17832.1 KXZ56684.1 - 5.3e-16 59.1 0.1 9.2e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KXZ56684.1 - 6e-15 55.0 0.2 2e-14 53.3 0.3 1.7 2 0 0 2 2 2 1 PUA domain Methyltr_RsmB-F PF01189.17 KXZ56685.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CLP1_P PF16575.5 KXZ56686.1 - 9.6e-31 107.0 0.0 1.4e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KXZ56686.1 - 6.7e-05 23.3 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KXZ56686.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXZ56686.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 KXZ56686.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase TPT PF03151.16 KXZ56687.1 - 2.5e-16 59.9 4.0 2.7e-16 59.8 4.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ56687.1 - 3.3e-06 27.3 15.1 0.001 19.2 4.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPPK_C PF12555.8 KXZ56687.1 - 0.19 11.8 0.4 0.19 11.8 0.4 3.2 3 2 1 4 4 4 0 Thiamine pyrophosphokinase C terminal Hist_deacetyl PF00850.19 KXZ56688.1 - 3.8e-63 213.8 0.0 4.9e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PTPLA PF04387.14 KXZ56690.1 - 6.3e-62 208.2 4.1 7.5e-62 207.9 4.1 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Bromodomain PF00439.25 KXZ56692.1 - 3.5e-21 75.1 0.0 6.7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 KXZ56692.1 - 4.1e-06 26.9 0.0 8.5e-05 22.7 0.0 2.7 4 0 0 4 4 4 1 Bromodomain extra-terminal - transcription regulation HsbA PF12296.8 KXZ56692.1 - 0.15 12.5 0.2 0.15 12.5 0.2 1.9 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF1846 PF08903.11 KXZ56692.1 - 0.3 9.6 0.7 0.4 9.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Pkinase PF00069.25 KXZ56693.1 - 5.1e-47 160.4 0.0 7.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56693.1 - 2.2e-46 158.3 0.0 4.1e-46 157.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KXZ56693.1 - 8.4e-15 54.6 0.1 3.8e-09 36.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56693.1 - 2.1e-11 43.0 0.0 0.00026 21.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXZ56693.1 - 8e-11 42.4 0.0 5.2e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ56693.1 - 5.9e-09 36.0 0.0 0.00012 22.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXZ56693.1 - 1.3e-07 32.0 0.0 3.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Arm_2 PF04826.13 KXZ56694.1 - 0.0018 17.8 0.0 0.095 12.1 0.0 2.4 2 0 0 2 2 2 2 Armadillo-like Arm PF00514.23 KXZ56694.1 - 0.012 15.6 1.4 0.38 10.9 0.1 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF815 PF05673.13 KXZ56696.1 - 1.5e-16 60.3 0.0 6.4e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_16 PF13191.6 KXZ56696.1 - 6.6e-05 23.4 0.4 0.00019 21.9 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KXZ56696.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXZ56696.1 - 0.059 13.6 0.0 0.18 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXZ56696.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA12 PF10443.9 KXZ56696.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein TIR_2 PF13676.6 KXZ56698.1 - 1.4e-15 58.0 0.0 2.8e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain SAM_2 PF07647.17 KXZ56698.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Arm PF00514.23 KXZ56698.1 - 0.006 16.6 0.5 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat SAM_1 PF00536.30 KXZ56698.1 - 0.016 15.6 0.0 0.85 10.1 0.0 2.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DEAD PF00270.29 KXZ56699.1 - 1.4e-48 165.0 0.0 2.1e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ56699.1 - 4.3e-32 110.8 0.0 3.3e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXZ56699.1 - 5.4e-05 23.3 0.0 9.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXZ56699.1 - 0.22 10.7 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3082 PF11282.8 KXZ56700.1 - 6.3e-25 87.2 4.7 6.3e-25 87.2 4.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3082) DUF4774 PF15999.5 KXZ56700.1 - 0.042 13.7 0.6 0.11 12.4 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) Glyco_transf_6 PF03414.13 KXZ56700.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 2OG-FeII_Oxy_4 PF13661.6 KXZ56701.1 - 0.00044 20.8 0.0 0.00086 19.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_C41 PF05417.11 KXZ56701.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease STI1 PF17830.1 KXZ56702.1 - 5.3e-09 35.9 0.3 9.6e-09 35.0 0.3 1.5 1 0 0 1 1 1 1 STI1 domain GatB_Yqey PF02637.18 KXZ56702.1 - 0.069 13.0 0.2 0.089 12.7 0.2 1.1 1 0 0 1 1 1 0 GatB domain DUF4821 PF16092.5 KXZ56703.1 - 9.3e-35 120.5 0.0 7.1e-27 94.7 0.0 3.7 3 1 0 3 3 3 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 KXZ56703.1 - 5.3e-05 22.6 0.0 0.0011 18.3 0.0 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXZ56703.1 - 0.01 15.1 0.1 0.048 12.9 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Mod_r PF07200.13 KXZ56704.1 - 0.0059 16.7 15.9 0.0059 16.7 15.9 7.9 2 2 5 7 7 7 2 Modifier of rudimentary (Mod(r)) protein DegQ PF08181.11 KXZ56704.1 - 0.58 10.3 7.9 0.68 10.1 1.3 3.1 2 0 0 2 2 2 0 DegQ (SacQ) family APC_N_CC PF16689.5 KXZ56704.1 - 2.8 8.1 29.9 7.3 6.7 0.2 8.0 8 0 0 8 8 8 0 Coiled-coil N-terminus of APC, dimerisation domain CEP209_CC5 PF16574.5 KXZ56705.1 - 3.6e-06 27.2 8.5 3.6e-06 27.2 8.5 10.7 7 2 4 11 11 11 1 Coiled-coil region of centrosome protein CE290 SOGA PF11365.8 KXZ56705.1 - 0.00086 20.4 96.5 0.024 15.8 0.2 12.1 7 3 3 12 12 12 6 Protein SOGA MAD PF05557.13 KXZ56705.1 - 0.0019 16.6 0.7 0.0019 16.6 0.7 7.3 5 3 0 6 6 6 1 Mitotic checkpoint protein GAS PF13851.6 KXZ56705.1 - 0.007 15.7 5.4 0.007 15.7 5.4 10.3 7 3 4 12 12 12 3 Growth-arrest specific micro-tubule binding Takusan PF04822.13 KXZ56705.1 - 0.0071 16.2 2.1 0.0071 16.2 2.1 6.6 5 1 0 6 6 6 2 Takusan CENP-F_leu_zip PF10473.9 KXZ56705.1 - 0.01 15.9 11.1 0.01 15.9 11.1 11.6 7 4 2 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KXZ56705.1 - 0.12 12.8 0.1 0.12 12.8 0.1 8.6 4 3 4 8 8 8 0 Fez1 Parvo_NS1 PF01057.17 KXZ56705.1 - 0.18 10.9 2.1 4.6 6.3 0.0 3.1 4 0 0 4 4 4 0 Parvovirus non-structural protein NS1 UPF0242 PF06785.11 KXZ56705.1 - 0.2 11.8 0.1 0.2 11.8 0.1 9.8 4 4 4 8 8 8 0 Uncharacterised protein family (UPF0242) N-terminus SNO PF01174.19 KXZ56706.1 - 5.2e-34 117.7 0.0 6.9e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family UQ_con PF00179.26 KXZ56706.1 - 3.1e-13 49.6 1.6 1.9e-12 47.0 1.1 2.1 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme GATase_3 PF07685.14 KXZ56706.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain His_Phos_1 PF00300.22 KXZ56707.1 - 4.5e-36 124.4 0.9 1.3e-28 100.1 0.7 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 KXZ56708.1 - 6.3e-59 199.9 0.0 3.7e-45 154.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Pkinase_Tyr PF07714.17 KXZ56709.1 - 1.2e-49 168.9 0.0 1.5e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXZ56709.1 - 3.5e-48 164.3 0.0 4.8e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXZ56709.1 - 1.6e-07 30.9 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXZ56709.1 - 0.00075 18.5 0.0 0.002 17.2 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KXZ56709.1 - 0.0028 17.6 0.1 0.0048 16.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXZ56709.1 - 0.029 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ADIP PF11559.8 KXZ56710.1 - 0.0024 17.9 15.8 0.48 10.5 2.3 3.2 3 0 0 3 3 3 2 Afadin- and alpha -actinin-Binding HALZ PF02183.18 KXZ56710.1 - 0.0034 17.6 5.7 0.0034 17.6 5.7 3.5 3 1 1 4 4 3 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 KXZ56710.1 - 0.0053 16.8 17.8 3.1 7.9 8.6 3.4 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein AIP3 PF03915.13 KXZ56710.1 - 0.011 14.9 5.8 0.043 12.9 5.8 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 DUF5320 PF17253.2 KXZ56710.1 - 0.021 15.9 3.0 0.4 11.8 0.0 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5320) DUF3540 PF12059.8 KXZ56710.1 - 0.022 14.6 2.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) ApoLp-III PF07464.11 KXZ56710.1 - 0.023 14.8 6.2 2 8.5 0.4 3.1 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Cep57_MT_bd PF06657.13 KXZ56710.1 - 0.025 15.0 0.8 0.025 15.0 0.8 3.1 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 KASH_CCD PF14662.6 KXZ56710.1 - 0.034 14.0 17.9 1.1 9.1 0.4 3.3 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 KXZ56710.1 - 0.045 13.3 9.5 0.59 9.7 0.1 3.1 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Rootletin PF15035.6 KXZ56710.1 - 0.062 13.3 20.5 0.44 10.6 6.4 3.2 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion THOC7 PF05615.13 KXZ56710.1 - 0.077 13.3 12.0 0.28 11.5 1.4 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 SOGA PF11365.8 KXZ56710.1 - 0.081 14.1 18.1 0.63 11.2 7.6 3.1 3 0 0 3 3 3 0 Protein SOGA DNA_photolyase PF00875.18 KXZ56710.1 - 0.098 12.7 1.5 0.98 9.4 0.3 2.4 2 0 0 2 2 2 0 DNA photolyase Dynamitin PF04912.14 KXZ56710.1 - 0.12 11.6 14.6 0.077 12.3 1.9 2.9 2 1 1 3 3 3 0 Dynamitin Paralemmin PF03285.15 KXZ56710.1 - 0.23 11.0 8.5 0.13 11.8 0.2 2.4 3 0 0 3 3 3 0 Paralemmin ApoO PF09769.9 KXZ56710.1 - 0.31 11.0 5.3 0.43 10.5 0.4 2.7 3 0 0 3 3 3 0 Apolipoprotein O SlyX PF04102.12 KXZ56710.1 - 0.35 11.5 13.2 0.41 11.3 1.3 3.6 3 1 0 3 3 3 0 SlyX RmuC PF02646.16 KXZ56710.1 - 0.41 9.7 11.7 2.3 7.3 0.1 3.1 3 0 0 3 3 3 0 RmuC family WD40_alt PF14077.6 KXZ56710.1 - 0.47 10.4 0.1 0.47 10.4 0.1 2.9 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF4407 PF14362.6 KXZ56710.1 - 0.61 9.4 6.9 3.1 7.1 6.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 KXZ56710.1 - 0.63 10.6 6.4 36 5.0 0.0 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Csm1_N PF18504.1 KXZ56710.1 - 0.77 10.1 19.6 0.42 11.0 0.5 4.4 3 2 1 4 4 4 0 Csm1 N-terminal domain YabA PF06156.13 KXZ56710.1 - 0.99 10.1 10.6 7.9 7.2 0.2 3.2 3 0 0 3 3 3 0 Initiation control protein YabA bZIP_1 PF00170.21 KXZ56710.1 - 1 9.5 21.7 0.99 9.5 0.6 4.1 3 1 0 3 3 3 0 bZIP transcription factor Prominin PF05478.11 KXZ56710.1 - 1.1 7.2 4.8 0.51 8.2 0.4 2.0 2 0 0 2 2 2 0 Prominin Ax_dynein_light PF10211.9 KXZ56710.1 - 1.1 9.2 17.0 3.4 7.6 0.4 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain Lebercilin PF15619.6 KXZ56710.1 - 1.1 8.8 24.4 0.041 13.5 2.1 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DivIVA PF05103.13 KXZ56710.1 - 1.3 9.2 12.3 2.6 8.1 0.1 3.6 3 1 0 3 3 3 0 DivIVA protein Spc7 PF08317.11 KXZ56710.1 - 1.7 7.5 15.1 1.5 7.7 0.1 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein Trimer_CC PF08954.11 KXZ56710.1 - 1.9 8.1 10.1 6 6.5 0.2 3.5 3 0 0 3 3 3 0 Trimerisation motif CLZ PF16526.5 KXZ56710.1 - 2.5 8.5 19.2 0.4 11.1 1.0 4.1 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMPIT PF07851.13 KXZ56710.1 - 3.8 6.7 6.9 9.4 5.4 0.7 2.6 3 0 0 3 3 3 0 TMPIT-like protein Prefoldin_2 PF01920.20 KXZ56710.1 - 4.3 7.3 17.9 3 7.8 1.3 3.7 3 1 1 4 4 4 0 Prefoldin subunit DUF1664 PF07889.12 KXZ56710.1 - 4.4 7.4 8.8 3.1 7.8 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 KXZ56710.1 - 5.1 7.3 19.6 1.7 8.9 0.2 3.7 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 TMCO5 PF14992.6 KXZ56710.1 - 6.7 6.2 12.2 9.2 5.7 2.6 2.9 3 0 0 3 3 3 0 TMCO5 family JIP_LZII PF16471.5 KXZ56710.1 - 6.7 7.0 16.8 0.7 10.1 0.3 3.5 3 1 0 3 3 2 0 JNK-interacting protein leucine zipper II UPF0242 PF06785.11 KXZ56710.1 - 6.8 6.7 14.6 3.3 7.8 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 KXZ56710.1 - 6.9 7.1 16.5 13 6.2 0.5 3.1 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 KXZ56710.1 - 7.4 7.0 19.3 35 4.8 0.2 3.5 3 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc24 PF08286.11 KXZ56710.1 - 8.1 6.7 14.2 5.8 7.2 0.4 3.4 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Tup_N PF08581.10 KXZ56710.1 - 8.3 6.8 12.9 0.67 10.3 0.3 3.6 3 1 0 3 3 3 0 Tup N-terminal COG5 PF10392.9 KXZ56710.1 - 8.8 6.5 12.9 3 8.0 3.7 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Jnk-SapK_ap_N PF09744.9 KXZ56710.1 - 9.9 6.4 26.2 1.1 9.5 9.1 3.0 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 FH2 PF02181.23 KXZ56711.1 - 1.7e-12 47.2 1.0 1.8e-08 33.9 0.1 2.0 1 1 1 2 2 2 2 Formin Homology 2 Domain Helicase_C PF00271.31 KXZ56712.1 - 1.3e-17 64.2 0.1 2.4e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ56712.1 - 2.6e-08 33.8 0.0 1.8e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4042 PF13251.6 KXZ56713.1 - 2.6e-32 112.0 6.8 2.9e-31 108.6 0.2 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF4042) HEAT PF02985.22 KXZ56713.1 - 0.0046 17.1 23.2 0.048 13.9 0.4 6.4 6 0 0 6 6 6 2 HEAT repeat IFRD PF05004.13 KXZ56713.1 - 0.075 12.1 0.6 1 8.4 0.0 2.9 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KXZ56713.1 - 0.67 10.4 20.4 0.14 12.6 0.6 5.5 5 2 0 5 5 5 0 HEAT repeats DUF2019 PF09450.10 KXZ56713.1 - 2.1 8.4 9.0 1 9.4 0.0 3.7 5 0 0 5 5 5 0 Domain of unknown function (DUF2019) HEAT_EZ PF13513.6 KXZ56713.1 - 4.1 8.0 32.6 2.5 8.7 3.1 7.1 7 1 1 8 8 8 0 HEAT-like repeat SBP56 PF05694.11 KXZ56714.1 - 2.7e-164 547.3 0.0 2.2e-144 481.7 0.0 2.0 1 1 1 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KXZ56714.1 - 0.0025 17.1 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller LVIVD PF08309.11 KXZ56714.1 - 0.13 11.6 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 LVIVD repeat LEA_5 PF00477.17 KXZ56715.1 - 3.6e-07 30.6 6.6 3.9e-07 30.5 6.6 1.2 1 0 0 1 1 1 1 Small hydrophilic plant seed protein LTD PF00932.19 KXZ56716.1 - 3.2e-11 43.6 0.0 5.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Lamin Tail Domain Fasciclin PF02469.22 KXZ56716.1 - 2.3e-07 31.1 0.0 1.9e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Fasciclin domain FKS1_dom1 PF14288.6 KXZ56720.1 - 0.0002 21.7 0.5 0.00029 21.2 0.5 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DEC-1_N PF04625.13 KXZ56720.1 - 1.3 8.0 4.5 1.6 7.7 4.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AAA PF00004.29 KXZ56721.1 - 2.8e-38 131.3 0.0 4.1e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXZ56721.1 - 1.1e-11 44.4 0.0 5e-11 42.2 0.0 2.3 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KXZ56721.1 - 2.5e-11 43.4 0.0 8.8e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KXZ56721.1 - 7.3e-05 22.6 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXZ56721.1 - 0.00027 21.2 0.3 0.021 15.1 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXZ56721.1 - 0.00028 20.9 0.0 0.0012 18.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXZ56721.1 - 0.00041 20.9 0.1 0.0032 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KXZ56721.1 - 0.0013 18.9 0.1 0.0057 16.8 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXZ56721.1 - 0.002 18.3 0.1 0.0058 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXZ56721.1 - 0.0028 17.1 0.1 0.0064 15.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXZ56721.1 - 0.0029 18.0 0.3 0.0084 16.5 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KXZ56721.1 - 0.0036 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KXZ56721.1 - 0.0044 16.8 0.0 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 KXZ56721.1 - 0.0058 15.9 0.2 0.019 14.2 0.1 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 KXZ56721.1 - 0.0099 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXZ56721.1 - 0.014 15.0 2.3 0.21 11.1 0.3 2.9 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 KXZ56721.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXZ56721.1 - 0.02 14.3 0.4 2.7 7.3 0.1 2.3 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 KXZ56721.1 - 0.029 13.9 0.1 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KXZ56721.1 - 0.044 13.2 0.1 6.3 6.1 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 KXZ56721.1 - 0.059 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KXZ56721.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KXZ56721.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GHMP_kinases_N PF00288.26 KXZ56722.1 - 1.8e-14 53.7 6.4 3.1e-14 53.0 0.9 2.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXZ56722.1 - 8e-08 32.5 0.4 2.3e-07 31.1 0.4 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KXZ56722.1 - 1.1e-06 28.0 0.0 4.4e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Glyco_transf_5 PF08323.11 KXZ56723.1 - 6e-65 219.3 0.1 8.3e-65 218.9 0.1 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXZ56723.1 - 8.1e-18 64.5 0.0 1.4e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXZ56723.1 - 2.8e-13 50.5 0.0 5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXZ56723.1 - 3.9e-05 23.7 0.7 0.0056 16.7 0.1 2.5 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KXZ56723.1 - 0.0026 18.2 0.6 0.009 16.5 0.1 2.1 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Metallophos PF00149.28 KXZ56724.1 - 3.7e-10 40.7 0.0 6.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nop14 PF04147.12 KXZ56724.1 - 0.00087 17.6 19.9 0.0012 17.2 19.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 KXZ56724.1 - 0.084 12.3 24.2 0.14 11.5 24.2 1.3 1 0 0 1 1 1 0 SDA1 GREB1 PF15782.5 KXZ56724.1 - 0.085 10.0 3.5 0.22 8.6 4.1 1.3 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer PID_2 PF14719.6 KXZ56724.1 - 0.21 11.4 2.3 0.37 10.6 2.3 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Nop53 PF07767.11 KXZ56724.1 - 0.22 10.9 19.1 0.39 10.0 19.1 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SpoIIIAH PF12685.7 KXZ56724.1 - 8.1 6.2 13.3 12 5.6 13.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein zf-rbx1 PF12678.7 KXZ56725.1 - 1.4e-05 25.2 0.2 2.4e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXZ56725.1 - 0.00065 20.0 1.3 0.013 15.9 0.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KXZ56725.1 - 0.02 14.7 4.7 0.037 13.8 0.8 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 KXZ56725.1 - 0.032 14.2 0.3 0.073 13.1 0.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KXZ56725.1 - 0.045 13.6 0.1 0.089 12.7 0.1 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXZ56725.1 - 0.6 10.2 2.8 1.6 8.9 2.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CitMHS PF03600.16 KXZ56725.1 - 3.7 6.7 6.9 5.6 6.1 6.9 1.3 1 0 0 1 1 1 0 Citrate transporter TPH PF13868.6 KXZ56726.1 - 1.3e-16 60.1 114.8 1.3e-16 60.1 114.8 2.7 2 1 0 2 2 2 1 Trichohyalin-plectin-homology domain GDA1_CD39 PF01150.17 KXZ56727.1 - 1.2e-56 192.3 0.0 5e-48 163.8 0.0 2.1 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family rRNA_processing PF08524.11 KXZ56727.1 - 5.9e-07 29.6 19.6 1.4e-06 28.4 19.6 1.6 1 1 0 1 1 1 1 rRNA processing TPT PF03151.16 KXZ56728.1 - 1.5e-07 31.1 5.2 3.5e-07 29.9 5.7 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXZ56728.1 - 7.3e-07 29.4 4.9 6.3e-06 26.4 0.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXZ56728.1 - 0.00016 21.0 3.2 0.00019 20.8 3.2 1.1 1 0 0 1 1 1 1 UAA transporter family Peptidase_C14 PF00656.22 KXZ56729.1 - 2.1e-52 178.5 0.0 2.7e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KXZ56729.1 - 0.00012 22.0 0.0 0.00045 20.2 0.0 1.8 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain CYSTM PF12734.7 KXZ56729.1 - 0.061 13.6 1.1 0.73 10.2 0.0 3.1 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Peptidase_C13 PF01650.18 KXZ56729.1 - 0.091 12.3 0.0 1.2 8.7 0.0 2.2 1 1 1 2 2 2 0 Peptidase C13 family Rad51 PF08423.11 KXZ56730.1 - 3.3e-22 79.0 0.1 4.1e-20 72.1 0.1 2.3 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 KXZ56730.1 - 6.4e-09 35.5 0.2 4.8e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KXZ56730.1 - 9.3e-09 35.1 2.9 9.7e-08 31.8 2.9 2.1 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 KXZ56730.1 - 2.6e-08 33.7 0.1 1.7e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KXZ56730.1 - 9.8e-06 25.1 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain CobU PF02283.16 KXZ56730.1 - 0.0002 21.0 0.2 0.0075 15.8 0.0 2.2 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_22 PF13401.6 KXZ56730.1 - 0.017 15.4 1.2 0.078 13.3 1.2 2.0 1 1 0 1 1 1 0 AAA domain Chorismate_bind PF00425.18 KXZ56730.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 chorismate binding enzyme ELP6 PF09807.9 KXZ56730.1 - 0.12 11.8 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Elongation complex protein 6 RWP-RK PF02042.15 KXZ56731.1 - 2.6e-21 75.3 0.1 4.3e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain Seadorna_VP6 PF07407.11 KXZ56731.1 - 0.074 12.0 0.5 0.11 11.5 0.5 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF1995 PF09353.10 KXZ56733.1 - 2.1e-47 161.7 0.0 2.7e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF4101 PF13355.6 KXZ56736.1 - 1.6e-21 76.9 0.0 2.3e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4101) Ribosomal_60s PF00428.19 KXZ56736.1 - 0.73 10.5 8.4 0.17 12.5 0.6 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pkinase PF00069.25 KXZ56737.1 - 3.6e-54 183.9 0.0 5.3e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56737.1 - 8.2e-28 97.4 0.0 1.5e-27 96.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXZ56737.1 - 2.8e-07 30.2 0.0 4.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXZ56737.1 - 0.00086 18.2 0.1 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXZ56737.1 - 0.018 15.0 1.4 0.059 13.3 0.7 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KXZ56737.1 - 0.025 13.9 1.0 0.084 12.2 0.8 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUDIX PF00293.28 KXZ56738.1 - 1.3e-11 44.6 0.3 1.4e-11 44.5 0.3 1.0 1 0 0 1 1 1 1 NUDIX domain RRM_1 PF00076.22 KXZ56739.1 - 3.9e-22 77.8 0.0 1.3e-09 37.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCRE PF17780.1 KXZ56739.1 - 1.3e-17 63.5 12.4 2.1e-17 62.9 12.4 1.3 1 0 0 1 1 1 1 OCRE domain zf-RanBP PF00641.18 KXZ56739.1 - 1.7e-05 24.1 2.0 2.6e-05 23.4 2.0 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Acetyltransf_3 PF13302.7 KXZ56741.1 - 3.5e-24 86.0 0.0 3.9e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXZ56741.1 - 9.7e-05 22.1 0.6 0.087 12.5 0.3 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXZ56741.1 - 0.0012 19.1 0.1 0.0016 18.6 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family HIRAN PF08797.11 KXZ56742.1 - 1.2e-07 31.5 0.0 2.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Profilin PF00235.19 KXZ56743.1 - 1.3e-31 109.5 0.0 1.4e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Profilin ATP-synt_C PF00137.21 KXZ56744.1 - 0.06 13.7 1.0 0.06 13.7 1.0 2.4 2 0 0 2 2 2 0 ATP synthase subunit C Toxin_25 PF08095.11 KXZ56745.1 - 0.54 10.3 1.9 0.62 10.1 0.1 2.0 2 0 0 2 2 2 0 Hefutoxin family Fer2 PF00111.27 KXZ56746.1 - 5.7e-13 48.6 0.2 1e-12 47.8 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NEMP PF10225.9 KXZ56747.1 - 4e-11 43.1 4.4 4.9e-11 42.8 4.4 1.1 1 0 0 1 1 1 1 NEMP family 2C_adapt PF08793.10 KXZ56747.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 2-cysteine adaptor domain FtsX PF02687.21 KXZ56747.1 - 2.4 8.7 7.4 0.15 12.6 0.5 2.2 2 1 0 2 2 2 0 FtsX-like permease family FAST_1 PF06743.15 KXZ56748.1 - 1.4e-07 31.4 0.1 0.71 9.9 0.1 5.3 5 1 1 6 6 6 4 FAST kinase-like protein, subdomain 1 CDC45 PF02724.14 KXZ56749.1 - 0.95 7.7 3.4 1 7.6 3.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Bindin PF02084.15 KXZ56750.1 - 0.011 16.0 5.2 0.015 15.6 5.2 1.2 1 0 0 1 1 1 0 Bindin UVR PF02151.19 KXZ56750.1 - 0.03 14.1 2.0 0.03 14.1 2.0 2.4 2 0 0 2 2 2 0 UvrB/uvrC motif DUF4602 PF15375.6 KXZ56751.1 - 6.5e-09 36.2 18.5 6.5e-09 36.2 18.5 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) GDPD PF03009.17 KXZ56753.1 - 1.5e-37 129.8 0.0 2.7e-37 128.9 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Isy1 PF06246.12 KXZ56754.1 - 5.9e-90 301.3 5.5 6.9e-90 301.1 5.5 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Helicase_C PF00271.31 KXZ56756.1 - 1.2e-15 57.8 0.0 2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXZ56756.1 - 0.006 15.8 0.0 0.0094 15.2 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SlyX PF04102.12 KXZ56756.1 - 4.1 8.1 5.3 8.8 7.0 0.1 2.6 2 0 0 2 2 2 0 SlyX SNF2_N PF00176.23 KXZ56757.1 - 2.1e-41 141.8 0.0 5.5e-37 127.3 0.0 2.3 2 1 0 2 2 2 2 SNF2 family N-terminal domain CBM_20 PF00686.19 KXZ56757.1 - 2.2e-09 37.1 0.0 3.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain ResIII PF04851.15 KXZ56757.1 - 8.2e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KXZ56757.1 - 0.00015 20.8 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 CH_2 PF06294.11 KXZ56759.1 - 1.2e-16 60.6 0.0 3e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 KXZ56759.1 - 7.7e-07 29.3 0.0 0.0054 16.9 0.0 3.6 3 0 0 3 3 3 1 Adenylate kinase EF-hand_1 PF00036.32 KXZ56759.1 - 0.012 15.1 0.0 0.038 13.5 0.0 1.9 1 0 0 1 1 1 0 EF hand Hydin_ADK PF17213.3 KXZ56759.1 - 0.044 14.1 0.0 0.044 14.1 0.0 5.3 5 1 0 5 5 5 0 Hydin Adenylate kinase-like domain RNR_Alpha PF17975.1 KXZ56759.1 - 3 8.4 4.8 7 7.2 3.5 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain AAA_17 PF13207.6 KXZ56759.1 - 4 7.9 10.4 36 4.8 0.0 4.8 4 1 0 4 4 4 0 AAA domain Tim17 PF02466.19 KXZ56760.1 - 6.7e-11 42.5 1.8 1.1e-10 41.8 1.8 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HCO3_cotransp PF00955.21 KXZ56760.1 - 0.16 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 HCO3- transporter family HA2 PF04408.23 KXZ56762.1 - 1e-24 86.9 0.0 2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXZ56762.1 - 3e-20 72.4 0.0 8.3e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXZ56762.1 - 5e-11 42.9 0.0 9.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXZ56762.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 KXZ56762.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain EMC3_TMCO1 PF01956.16 KXZ56763.1 - 2.6e-15 56.6 0.1 3.7e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Sensor PF13796.6 KXZ56763.1 - 0.00068 19.7 3.2 0.00086 19.4 3.2 1.1 1 0 0 1 1 1 1 Putative sensor CHD5 PF04420.14 KXZ56763.1 - 0.96 9.3 3.7 0.77 9.6 1.9 1.8 1 1 1 2 2 2 0 CHD5-like protein Aminotran_3 PF00202.21 KXZ56764.1 - 4e-87 292.5 0.0 5.1e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ParA PF10609.9 KXZ56765.1 - 7.3e-63 212.3 0.2 1.2e-55 188.7 0.0 2.1 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 KXZ56765.1 - 0.0022 17.9 0.3 0.0042 17.0 0.1 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KXZ56765.1 - 0.0028 17.7 0.1 0.0087 16.1 0.1 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MDMPI_N PF11716.8 KXZ56765.1 - 0.053 14.2 0.8 0.18 12.5 0.1 1.9 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Rxt3 PF08642.10 KXZ56766.1 - 2e-11 44.8 0.6 9.7e-10 39.3 0.1 2.3 1 1 1 2 2 2 2 Histone deacetylation protein Rxt3 Acyltransferase PF01553.21 KXZ56767.1 - 1.2e-15 57.3 0.0 1.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CCT PF06203.14 KXZ56768.1 - 0.00026 21.0 0.9 0.00047 20.1 0.9 1.4 1 0 0 1 1 1 1 CCT motif Phospholip_B PF04916.13 KXZ56769.1 - 1.3e-94 317.7 0.0 1.1e-69 235.5 0.0 3.0 2 1 1 3 3 3 3 Phospholipase B YfcL PF08891.11 KXZ56769.1 - 0.016 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 YfcL protein SIMPL PF04402.14 KXZ56769.1 - 0.093 13.2 0.2 0.093 13.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF541) Copper-bind PF00127.20 KXZ56770.1 - 2.3e-34 117.8 0.0 2.9e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 KXZ56770.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Cupredoxin-like domain Pyr_redox_2 PF07992.14 KXZ56771.1 - 3.3e-15 56.1 0.0 5.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXZ56771.1 - 0.38 11.3 2.2 16 6.2 0.4 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SRP_TPR_like PF17004.5 KXZ56772.1 - 6.8e-10 39.0 0.0 2.7e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Putative TPR-like repeat TPR_2 PF07719.17 KXZ56772.1 - 5.3e-06 26.1 17.4 0.19 11.9 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ56772.1 - 8.7e-05 22.7 0.8 8.7e-05 22.7 0.8 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXZ56772.1 - 0.00038 20.6 0.0 0.00038 20.6 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ56772.1 - 0.00052 20.6 22.4 0.14 13.0 0.0 6.6 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ56772.1 - 0.0022 18.5 23.9 0.0033 17.9 0.6 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ56772.1 - 0.01 16.0 7.4 17 5.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ56772.1 - 0.014 15.2 7.0 0.67 9.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ56772.1 - 0.029 14.6 18.8 6.4 7.1 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ56772.1 - 0.049 14.3 31.4 1.7 9.4 0.0 6.3 3 2 4 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ56772.1 - 0.076 12.9 11.8 0.47 10.4 1.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ56772.1 - 0.24 11.5 3.4 0.42 10.7 0.0 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KXZ56772.1 - 1.6 9.5 13.0 1.2 9.9 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat THF_DHG_CYH_C PF02882.19 KXZ56773.1 - 1.3e-66 222.8 0.2 2.3e-66 222.0 0.2 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KXZ56773.1 - 1.6e-23 83.2 1.1 2.6e-21 76.1 0.0 2.3 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KXZ56773.1 - 0.024 13.6 0.2 0.041 12.8 0.2 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family THOC7 PF05615.13 KXZ56775.1 - 3.4e-22 79.2 8.6 3.4e-22 79.2 8.6 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 Atg14 PF10186.9 KXZ56775.1 - 0.0093 15.1 5.2 0.014 14.5 5.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 COMPASS-Shg1 PF05205.12 KXZ56775.1 - 0.13 13.0 4.0 3.1 8.6 0.1 2.2 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 E1_UFD PF09358.10 KXZ56775.1 - 0.15 12.8 0.1 0.31 11.8 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin fold domain HIP1_clath_bdg PF16515.5 KXZ56775.1 - 0.58 10.8 10.8 0.19 12.4 5.5 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 KXZ56775.1 - 1.7 8.7 13.7 0.4 10.8 8.0 2.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4355 PF14265.6 KXZ56775.1 - 1.7 8.9 13.6 2.8 8.2 8.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF4407 PF14362.6 KXZ56775.1 - 1.7 7.9 11.5 2.5 7.4 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KXZ56775.1 - 9.8 6.5 19.7 2.2 8.6 12.1 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4611 PF15387.6 KXZ56776.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) mTERF PF02536.14 KXZ56777.1 - 2e-26 92.7 0.0 5.8e-26 91.2 0.0 1.9 1 1 0 1 1 1 1 mTERF DUF1497 PF07384.11 KXZ56777.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) His_Phos_1 PF00300.22 KXZ56778.1 - 2.3e-27 96.0 0.0 3.4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SlyX PF04102.12 KXZ56778.1 - 0.0082 16.7 0.8 0.0082 16.7 0.8 2.1 3 0 0 3 3 3 1 SlyX DUF4407 PF14362.6 KXZ56778.1 - 0.07 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 KXZ56778.1 - 0.09 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Guanylate_cyc PF00211.20 KXZ56779.1 - 0.055 13.1 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain AMP-binding PF00501.28 KXZ56780.1 - 9e-40 136.5 0.0 1.4e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXZ56780.1 - 3.2e-08 34.4 0.4 7.4e-08 33.3 0.4 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_5 PF13202.6 KXZ56781.1 - 0.0019 17.6 0.1 0.0033 16.9 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXZ56781.1 - 0.0034 16.8 0.1 0.0062 16.0 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXZ56781.1 - 0.0042 16.9 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain Myelin_PLP PF01275.19 KXZ56783.1 - 0.26 11.1 17.7 1.6 8.6 11.7 2.3 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) DUF5423 PF17461.2 KXZ56783.1 - 1.1 8.1 3.3 2.2 7.0 3.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Pkinase PF00069.25 KXZ56784.1 - 1.2e-29 103.5 0.0 1.8e-26 93.1 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56784.1 - 7.4e-12 45.1 0.0 5.7e-10 38.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXZ56784.1 - 0.093 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_77 PF02446.17 KXZ56785.1 - 3.5e-145 484.5 0.0 5.1e-145 483.9 0.0 1.2 1 0 0 1 1 1 1 4-alpha-glucanotransferase DUF1619 PF07773.11 KXZ56785.1 - 1e-39 137.4 1.4 4.6e-38 131.9 1.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) Chorismate_bind PF00425.18 KXZ56786.1 - 7.4e-34 117.5 0.0 1.2e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KXZ56786.1 - 9.1e-24 84.3 0.0 6.2e-15 55.5 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KXZ56786.1 - 3.7e-12 46.6 0.0 1.2e-08 35.3 0.0 2.3 2 0 0 2 2 2 2 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KXZ56786.1 - 0.0014 18.5 0.8 0.018 14.8 0.8 2.1 1 1 0 1 1 1 1 Peptidase C26 Chorismate_bind PF00425.18 KXZ56787.1 - 3.7e-41 141.4 1.1 1.1e-39 136.6 1.1 2.0 1 1 0 1 1 1 1 chorismate binding enzyme DUF1206 PF06724.11 KXZ56788.1 - 0.038 14.1 0.5 0.038 14.1 0.5 3.4 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1206) Pam16 PF03656.13 KXZ56788.1 - 0.57 10.2 2.8 1.6 8.8 0.2 2.5 2 0 0 2 2 2 0 Pam16 Sulfotransfer_2 PF03567.14 KXZ56789.1 - 0.012 15.5 0.1 0.098 12.5 0.1 2.0 1 1 0 1 1 1 0 Sulfotransferase family Ank_3 PF13606.6 KXZ56790.1 - 0.0034 17.8 0.2 0.12 13.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXZ56790.1 - 0.04 14.4 0.3 17 6.0 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KXZ56790.1 - 0.11 13.1 0.0 0.32 11.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Dynein_light PF01221.18 KXZ56792.1 - 4.3e-42 142.3 1.0 4.7e-42 142.2 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Carboxyl_trans PF01039.22 KXZ56793.1 - 8.5e-134 446.9 0.2 1.4e-132 442.9 0.2 2.0 1 1 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KXZ56793.1 - 1.7e-05 24.4 0.5 0.0062 16.1 0.1 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) NAD_binding_10 PF13460.6 KXZ56794.1 - 2.3e-21 76.5 0.0 4.5e-21 75.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXZ56794.1 - 0.0022 17.6 0.0 0.0099 15.5 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family EPSP_synthase PF00275.20 KXZ56795.1 - 4.9e-130 434.0 0.0 5.7e-130 433.8 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Ribosomal_L17 PF01196.19 KXZ56796.1 - 2e-27 95.9 0.4 2.4e-27 95.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Sec23_trunk PF04811.15 KXZ56797.1 - 1.1e-66 224.8 0.0 1.6e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KXZ56797.1 - 4.1e-22 78.7 0.0 9.9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KXZ56797.1 - 7.7e-21 73.9 0.0 1.4e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KXZ56797.1 - 1.4e-15 57.0 5.8 3.7e-15 55.7 5.8 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXZ56797.1 - 2e-13 50.1 0.0 5.6e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Glyco_trans_4_4 PF13579.6 KXZ56797.1 - 0.0095 16.4 0.3 0.045 14.2 0.1 2.3 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Vps36-NZF-N PF16988.5 KXZ56797.1 - 0.053 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc_ribbon_10 PF10058.9 KXZ56797.1 - 0.25 11.1 5.0 0.04 13.7 0.9 1.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Sin3a_C PF16879.5 KXZ56798.1 - 5.1e-42 144.6 0.0 5e-40 138.0 0.0 2.9 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KXZ56798.1 - 3.9e-37 126.1 5.8 5.6e-14 52.0 0.1 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KXZ56798.1 - 4.5e-32 110.0 0.1 1.1e-31 108.8 0.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor p450 PF00067.22 KXZ56799.1 - 1.1e-35 123.4 0.0 3.9e-22 78.6 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Sin3a_C PF16879.5 KXZ56800.1 - 1.6e-50 172.4 0.0 5e-49 167.5 0.0 3.1 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KXZ56800.1 - 6.6e-41 138.2 11.1 5.7e-16 58.4 1.7 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KXZ56800.1 - 1.2e-31 108.6 0.0 3e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Med28 PF11594.8 KXZ56800.1 - 0.059 13.4 0.6 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 Mediator complex subunit 28 DUF1722 PF08349.11 KXZ56800.1 - 0.28 11.5 3.3 7.1 6.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) DUF1160 PF06648.11 KXZ56800.1 - 0.8 9.7 4.2 10 6.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1160) SelP_N PF04592.14 KXZ56800.1 - 1.4 8.3 8.3 1.4 8.3 5.6 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Meth_synt_2 PF01717.18 KXZ56801.1 - 3.9e-149 496.3 0.0 1.6e-147 491.0 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXZ56801.1 - 1.1e-74 251.8 0.0 5.9e-67 226.4 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KXZ56801.1 - 0.071 12.9 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 Short C-terminal domain PDZ_1 PF12812.7 KXZ56802.1 - 1.6e-25 88.9 0.0 8.3e-17 61.0 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain PDZ_6 PF17820.1 KXZ56802.1 - 1.4e-18 66.5 0.1 8.3e-08 32.0 0.3 4.6 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.6 KXZ56802.1 - 1.2e-16 62.0 7.0 1.9e-10 41.8 0.1 4.3 2 2 1 3 3 3 2 Trypsin-like peptidase domain PDZ PF00595.24 KXZ56802.1 - 1.1e-12 48.1 0.0 3.1e-05 24.2 0.0 3.7 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KXZ56802.1 - 1.3e-11 44.7 0.0 0.0018 18.6 0.0 4.7 5 0 0 5 5 5 2 PDZ domain Peptidase_S46 PF10459.9 KXZ56802.1 - 0.0011 17.7 0.0 0.0097 14.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase S46 Tricorn_PDZ PF14685.6 KXZ56802.1 - 0.0048 16.8 0.0 8.9 6.4 0.0 3.6 4 0 0 4 4 4 1 Tricorn protease PDZ domain Trypsin PF00089.26 KXZ56802.1 - 0.0056 16.5 0.4 1.4 8.6 0.0 2.6 2 1 1 3 3 3 2 Trypsin Peptidase_S32 PF05579.13 KXZ56802.1 - 0.067 12.4 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.16 KXZ56802.1 - 0.083 12.4 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) 5_nucleotid_C PF02872.18 KXZ56803.1 - 3.5e-40 137.8 0.0 1.4e-39 135.8 0.0 1.9 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXZ56803.1 - 0.00012 22.7 0.1 0.00024 21.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_1 PF00667.20 KXZ56804.1 - 1.2e-25 90.4 0.0 3.2e-25 89.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXZ56804.1 - 6.2e-23 81.6 0.0 1.2e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXZ56804.1 - 1.3e-17 64.4 0.0 2.7e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXZ56804.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain NAD_binding_5 PF07994.12 KXZ56805.1 - 8.7e-143 475.5 0.0 1e-142 475.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KXZ56805.1 - 3.8e-48 162.3 0.0 6.5e-48 161.5 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase BLUF PF04940.12 KXZ56805.1 - 0.024 14.7 0.1 0.046 13.9 0.1 1.4 1 0 0 1 1 1 0 Sensors of blue-light using FAD Arm PF00514.23 KXZ56806.1 - 9.9e-09 35.0 0.2 0.00032 20.6 0.0 4.0 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat WD40 PF00400.32 KXZ56807.1 - 0.0089 16.9 1.7 1.2 10.1 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat CENP-T_C PF15511.6 KXZ56808.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ56808.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ56808.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ56808.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ56808.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ56808.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ56808.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KXZ56809.1 - 2.7e-29 102.2 0.0 3.7e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXZ56809.1 - 0.024 14.7 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ56809.1 - 0.048 14.0 0.0 0.07 13.5 0.0 1.2 1 0 0 1 1 1 0 CENP-S protein DUF746 PF05344.11 KXZ56809.1 - 0.062 13.1 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) LCM PF04072.14 KXZ56810.1 - 3.8e-31 108.5 0.0 9.8e-22 77.8 0.0 2.2 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase DNA_pol_B_exo1 PF03104.19 KXZ56812.1 - 3.3e-42 144.8 0.0 4.4e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Lzipper-MIP1 PF14389.6 KXZ56812.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF1744 PF08490.12 KXZ56813.1 - 2.5e-83 279.9 0.0 1.4e-41 142.4 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 KXZ56813.1 - 3e-14 52.6 0.0 7.9e-07 28.1 0.0 3.2 3 0 0 3 3 3 3 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXZ56813.1 - 3.4e-12 46.2 0.0 4.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 KXZ56813.1 - 0.0048 16.9 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 RNase_H superfamily PRIMA1 PF16101.5 KXZ56813.1 - 1.5 8.9 3.9 4.5 7.3 3.9 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Histone PF00125.24 KXZ56815.1 - 5.5e-48 162.6 0.1 6.3e-48 162.5 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXZ56815.1 - 0.00011 22.5 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXZ56815.1 - 0.00034 20.7 0.1 0.00045 20.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXZ56815.1 - 0.0042 17.3 0.1 0.0059 16.9 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXZ56815.1 - 0.008 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KXZ56816.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ56816.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ56816.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ56816.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ56816.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ56816.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ56816.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UDG PF03167.19 KXZ56817.1 - 3.9e-09 36.7 0.0 7.1e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Serglycin PF04360.12 KXZ56818.1 - 0.02 14.8 3.5 0.033 14.2 3.5 1.2 1 0 0 1 1 1 0 Serglycin p450 PF00067.22 KXZ56821.1 - 3.4e-46 157.9 0.0 3.2e-31 108.6 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 CENP-T_C PF15511.6 KXZ56822.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ56822.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ56822.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ56822.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ56822.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ56822.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ56822.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Pkinase PF00069.25 KXZ56823.1 - 1.9e-28 99.6 0.0 1e-18 67.6 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56823.1 - 1.2e-27 96.8 0.0 4e-21 75.5 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ56823.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXZ56823.1 - 0.15 12.0 2.9 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family CENP-T_C PF15511.6 KXZ56824.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXZ56824.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KXZ56824.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXZ56824.1 - 0.0014 18.9 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXZ56824.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KXZ56824.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXZ56824.1 - 0.022 14.8 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated RcbX PF02341.15 KXZ56825.1 - 5.8e-05 23.3 0.3 0.057 13.7 0.2 2.1 1 1 1 2 2 2 2 RbcX protein Sbi-IV PF11621.8 KXZ56825.1 - 0.026 14.9 0.1 0.039 14.3 0.1 1.2 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI PsbQ PF05757.11 KXZ56826.1 - 0.83 9.3 3.6 1.1 9.0 3.6 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) EamA PF00892.20 KXZ56827.1 - 1.7e-06 28.2 11.6 1.7e-06 28.2 11.6 3.4 3 0 0 3 3 3 2 EamA-like transporter family Ssl1 PF04056.14 KXZ56829.1 - 2.5e-68 229.7 0.0 3.2e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KXZ56829.1 - 9.4e-07 29.5 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXZ56829.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain Tfb4 PF03850.14 KXZ56829.1 - 0.28 10.6 0.5 1.5 8.3 0.0 1.9 2 0 0 2 2 2 0 Transcription factor Tfb4 2OG-FeII_Oxy_3 PF13640.6 KXZ56830.1 - 7.7e-15 55.6 0.0 1.2e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ56830.1 - 1.6e-08 35.0 0.0 2.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KXZ56831.1 - 5.7e-38 130.8 0.1 1.6e-23 83.2 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 2OG-FeII_Oxy_3 PF13640.6 KXZ56832.1 - 6.4e-16 59.0 0.0 9.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXZ56832.1 - 7.7e-09 36.0 0.0 1.2e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1_like PF12832.7 KXZ56834.1 - 2.4e-29 102.4 0.0 4.7e-29 101.4 0.0 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KXZ56834.1 - 9.7e-15 54.3 11.7 1.9e-14 53.4 11.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 KXZ56834.1 - 0.00037 19.4 1.5 0.00053 18.9 1.5 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 KXZ56834.1 - 0.00039 19.5 1.5 0.00039 19.5 1.5 1.4 2 0 0 2 2 2 1 Nucleoside H+ symporter SNF2_N PF00176.23 KXZ56835.1 - 1.6e-61 208.0 0.0 3.1e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain MFS_1_like PF12832.7 KXZ56835.1 - 2.7e-23 82.5 1.7 4.1e-23 81.9 1.7 1.1 1 0 0 1 1 1 1 MFS_1 like family Helicase_C PF00271.31 KXZ56835.1 - 7.5e-19 68.1 0.0 1.7e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KXZ56835.1 - 4.3e-18 64.9 0.0 1.6e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KXZ56835.1 - 4.2e-09 36.6 0.0 9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 KXZ56835.1 - 3e-05 24.1 0.1 0.0058 16.8 0.0 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4208 PF13907.6 KXZ56835.1 - 3.3e-05 24.2 0.0 0.00012 22.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 KXZ56835.1 - 0.00062 19.0 0.0 0.002 17.4 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Nuc_H_symport PF03825.16 KXZ56835.1 - 0.00065 18.8 0.0 0.00091 18.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter SLIDE PF09111.10 KXZ56835.1 - 0.0024 17.9 0.3 0.013 15.5 0.0 2.3 3 0 0 3 3 3 1 SLIDE SWI2_SNF2 PF18766.1 KXZ56835.1 - 0.019 14.7 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase MFS_1 PF07690.16 KXZ56835.1 - 0.16 10.9 4.0 0.29 10.0 4.0 1.4 1 0 0 1 1 1 0 Major Facilitator Superfamily CPSF100_C PF13299.6 KXZ56835.1 - 0.65 10.2 4.0 2 8.6 4.0 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal VSG_B PF13206.6 KXZ56835.1 - 2.1 7.5 9.1 2.8 7.1 7.8 1.8 2 0 0 2 2 2 0 Trypanosomal VSG domain PI3K_1B_p101 PF10486.9 KXZ56835.1 - 5.7 4.6 4.8 9 3.9 4.8 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UFD1 PF03152.14 KXZ56836.1 - 1.6e-26 92.8 0.0 4.4e-26 91.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 KXZ56836.1 - 2.1e-09 37.4 0.0 4.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF3306 PF11748.8 KXZ56836.1 - 6.4 7.7 13.6 2 9.3 10.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) F-box-like_2 PF13013.6 KXZ56839.1 - 0.12 12.4 0.6 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 F-box-like domain Helicase_C PF00271.31 KXZ56841.1 - 4.9e-21 75.2 0.0 1.6e-19 70.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXZ56841.1 - 3.9e-10 40.3 4.5 1.5e-09 38.5 4.5 2.1 1 1 0 1 1 1 1 RecQ zinc-binding Radical_SAM PF04055.21 KXZ56841.1 - 0.11 12.8 0.1 5.2 7.4 0.1 2.7 3 0 0 3 3 3 0 Radical SAM superfamily p450 PF00067.22 KXZ56842.1 - 1.8e-34 119.3 0.1 2e-21 76.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Kinesin PF00225.23 KXZ56844.1 - 1.5e-31 109.6 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain V-SNARE_C PF12352.8 KXZ56845.1 - 0.00095 19.4 1.8 0.00095 19.4 1.8 2.1 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF4200 PF13863.6 KXZ56845.1 - 0.0025 18.2 5.1 0.0025 18.2 5.1 2.3 1 1 0 2 2 2 1 Domain of unknown function (DUF4200) Sec8_exocyst PF04048.14 KXZ56845.1 - 0.0025 17.7 1.7 0.013 15.4 0.4 2.3 1 1 1 2 2 2 1 Sec8 exocyst complex component specific domain Atg14 PF10186.9 KXZ56845.1 - 0.0032 16.6 5.1 0.0046 16.1 5.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 KXZ56845.1 - 0.014 14.4 5.6 0.018 14.1 4.5 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KXZ56845.1 - 0.035 14.2 4.9 0.25 11.4 0.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 KXZ56845.1 - 0.042 14.1 6.0 0.22 11.8 0.2 2.9 1 1 1 3 3 3 0 Tup N-terminal Spc7 PF08317.11 KXZ56845.1 - 0.062 12.2 15.0 0.15 10.9 14.1 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.20 KXZ56845.1 - 0.065 12.6 21.6 0.091 12.1 21.6 1.1 1 0 0 1 1 1 0 Tropomyosin DUF4407 PF14362.6 KXZ56845.1 - 0.068 12.5 14.3 0.12 11.7 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MscS_porin PF12795.7 KXZ56845.1 - 0.079 12.5 28.0 0.3 10.6 17.1 2.6 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Cast PF10174.9 KXZ56845.1 - 0.19 9.9 15.1 1.8 6.7 15.1 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF4201 PF13870.6 KXZ56845.1 - 0.22 11.2 8.8 0.8 9.4 8.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TBCA PF02970.16 KXZ56845.1 - 0.27 11.6 8.5 30 5.1 6.9 3.0 1 1 1 2 2 2 0 Tubulin binding cofactor A UPF0449 PF15136.6 KXZ56845.1 - 0.27 11.7 6.1 0.72 10.4 5.0 2.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 AAA_13 PF13166.6 KXZ56845.1 - 0.27 9.8 8.4 0.47 9.0 8.4 1.3 1 1 0 1 1 1 0 AAA domain COG2 PF06148.11 KXZ56845.1 - 0.33 11.1 10.2 0.85 9.7 2.0 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapD PF07072.11 KXZ56845.1 - 0.33 10.7 6.9 1.8 8.3 0.7 2.2 2 0 0 2 2 2 0 Cell division protein Fib_alpha PF08702.10 KXZ56845.1 - 0.45 10.7 1.4 0.83 9.8 0.2 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KXZ56845.1 - 0.46 10.0 11.7 0.73 9.4 11.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MukF_M PF17192.4 KXZ56845.1 - 0.46 10.2 5.2 0.79 9.5 5.2 1.4 1 0 0 1 1 1 0 MukF middle domain Snapin_Pallidin PF14712.6 KXZ56845.1 - 0.54 10.7 6.9 0.7 10.4 0.8 2.5 1 1 1 2 2 2 0 Snapin/Pallidin Prominin PF05478.11 KXZ56845.1 - 0.58 8.0 1.0 0.82 7.5 1.0 1.3 1 0 0 1 1 1 0 Prominin HemX PF04375.14 KXZ56845.1 - 0.64 9.3 20.7 0.4 9.9 6.4 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2203 PF09969.9 KXZ56845.1 - 0.67 10.7 9.8 6.2 7.6 4.1 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 KXZ56845.1 - 0.99 9.7 2.8 3.7 7.9 0.2 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KXZ56845.1 - 1 9.9 23.9 1.9 9.0 14.2 2.7 1 1 2 3 3 3 0 Apg6 coiled-coil region ATG16 PF08614.11 KXZ56845.1 - 1 9.6 24.2 4.1 7.6 24.2 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 KXZ56845.1 - 1.1 9.6 4.3 2.8 8.3 1.3 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 PF09787.9 KXZ56845.1 - 1.2 8.5 12.5 2.6 7.4 12.6 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF3450 PF11932.8 KXZ56845.1 - 1.4 8.1 16.4 3.8 6.7 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 KXZ56845.1 - 1.6 9.3 8.2 10 6.8 8.1 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fmp27_WPPW PF10359.9 KXZ56845.1 - 1.9 7.3 6.6 2.9 6.7 6.5 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RmuC PF02646.16 KXZ56845.1 - 2.1 7.4 8.2 0.53 9.4 2.3 2.2 1 1 0 2 2 2 0 RmuC family OmpH PF03938.14 KXZ56845.1 - 2.1 8.7 15.9 6.6e+02 0.6 15.9 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ERM PF00769.19 KXZ56845.1 - 2.2 8.0 27.2 18 5.0 27.0 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Baculo_PEP_C PF04513.12 KXZ56845.1 - 2.2 8.3 5.9 4.1 7.5 2.8 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 KXZ56845.1 - 2.5 8.4 13.3 0.73 10.1 4.5 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2205 PF10224.9 KXZ56845.1 - 2.5 8.1 6.3 0.75 9.8 1.7 2.3 2 0 0 2 2 2 0 Short coiled-coil protein Flagellin_C PF00700.21 KXZ56845.1 - 2.8 8.4 9.9 4.8 7.6 1.2 3.0 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region HIP1_clath_bdg PF16515.5 KXZ56845.1 - 3.1 8.4 17.3 2.3 8.9 3.4 2.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 JIP_LZII PF16471.5 KXZ56845.1 - 4.3 7.6 8.8 1.9 8.7 3.2 2.7 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II ADIP PF11559.8 KXZ56845.1 - 4.3 7.4 17.8 8.6 6.4 4.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 KXZ56845.1 - 4.5 6.4 4.9 1.4 8.1 1.2 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 KXZ56845.1 - 4.8 7.0 10.0 1.4 8.7 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3053 PF11254.8 KXZ56845.1 - 5 6.6 7.8 0.58 9.7 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Prefoldin_2 PF01920.20 KXZ56845.1 - 5.4 7.0 7.1 19 5.2 1.8 3.0 1 1 1 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 KXZ56845.1 - 6.7 6.8 25.8 1.7 8.7 15.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HEAT_2 PF13646.6 KXZ56846.1 - 0.0003 21.1 8.7 0.067 13.6 0.1 5.6 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KXZ56846.1 - 0.0066 16.9 0.7 0.0066 16.9 0.7 5.0 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 KXZ56846.1 - 0.037 14.3 0.0 0.037 14.3 0.0 5.4 7 0 0 7 7 7 0 HEAT repeat MCM PF00493.23 KXZ56847.1 - 2.5e-101 337.5 0.2 4.1e-101 336.7 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXZ56847.1 - 1.5e-35 121.8 0.7 3.4e-35 120.7 0.1 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KXZ56847.1 - 1.5e-23 83.0 3.6 3.9e-23 81.7 3.6 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXZ56847.1 - 2.9e-14 53.5 0.0 8.6e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXZ56847.1 - 3.8e-08 33.0 0.0 6.5e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM6_C PF18263.1 KXZ56847.1 - 9.8e-08 32.2 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain AAA_3 PF07726.11 KXZ56847.1 - 0.00015 21.7 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXZ56847.1 - 0.00061 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXZ56847.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Topoisom_I_N PF02919.15 KXZ56848.1 - 3.1e-92 307.9 4.7 3.1e-92 307.9 4.7 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KXZ56848.1 - 2.1e-77 259.5 9.1 2.1e-77 259.5 9.1 1.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KXZ56848.1 - 7.8e-34 115.4 0.3 7.8e-34 115.4 0.3 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain Phage_Gp17 PF17549.2 KXZ56848.1 - 0.021 14.8 1.0 0.052 13.6 0.3 2.0 2 0 0 2 2 2 0 Gene Product 17 TMPIT PF07851.13 KXZ56848.1 - 0.15 11.2 7.3 0.31 10.3 7.3 1.5 1 0 0 1 1 1 0 TMPIT-like protein His_binding PF02098.16 KXZ56848.1 - 0.21 11.6 2.4 0.34 10.9 0.8 2.2 2 0 0 2 2 2 0 Tick histamine binding protein Med9 PF07544.13 KXZ56848.1 - 0.28 11.3 5.9 0.93 9.6 5.9 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PRKG1_interact PF15898.5 KXZ56848.1 - 0.98 10.4 13.1 0.63 11.0 7.6 3.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain LCD1 PF09798.9 KXZ56848.1 - 1.4 7.4 11.2 0.09 11.3 5.3 1.9 2 0 0 2 2 2 0 DNA damage checkpoint protein Atg14 PF10186.9 KXZ56848.1 - 6.9 5.7 9.9 1.7 7.7 6.3 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.32 KXZ56849.1 - 1.1e-51 171.6 19.2 2.7e-06 28.0 0.2 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat U-box PF04564.15 KXZ56849.1 - 1.4e-11 44.4 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 U-box domain PQQ_3 PF13570.6 KXZ56849.1 - 9.6e-11 41.8 9.8 0.24 12.0 0.1 7.1 7 0 0 7 7 7 2 PQQ-like domain Nup160 PF11715.8 KXZ56849.1 - 1.5e-10 40.3 17.1 0.061 12.0 0.2 6.9 1 1 6 7 7 7 5 Nucleoporin Nup120/160 WD40_like PF17005.5 KXZ56849.1 - 1.3e-06 28.0 0.0 0.08 12.2 0.0 3.3 1 1 0 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 KXZ56849.1 - 0.00012 22.1 0.1 6.4 6.9 0.0 4.9 1 1 6 7 7 7 1 Ciliary BBSome complex subunit 2, middle region zf-rbx1 PF12678.7 KXZ56849.1 - 0.00012 22.3 0.0 0.00037 20.7 0.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain TMEM191C PF15194.6 KXZ56849.1 - 0.00049 20.3 0.3 12 6.2 0.0 4.8 2 2 2 5 5 5 0 TMEM191C family zf-RING_2 PF13639.6 KXZ56849.1 - 0.0057 17.0 1.3 0.016 15.5 0.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXZ56849.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXZ56849.1 - 0.027 14.5 0.0 0.088 12.9 0.0 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Nucleoporin_N PF08801.11 KXZ56849.1 - 0.035 12.9 0.4 0.51 9.0 0.0 2.8 1 1 1 3 3 3 0 Nup133 N terminal like DUF5634_N PF18672.1 KXZ56849.1 - 0.046 13.5 0.2 0.46 10.2 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5634) zf-Nse PF11789.8 KXZ56849.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit AsnC_trans_reg PF01037.21 KXZ56849.1 - 0.31 11.0 4.1 85 3.2 0.0 5.1 5 2 1 7 7 7 0 Lrp/AsnC ligand binding domain Ge1_WD40 PF16529.5 KXZ56849.1 - 0.47 9.4 6.7 4.3 6.2 0.1 3.7 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RIB43A PF05914.12 KXZ56850.1 - 1.4e-88 297.2 48.5 1.7e-88 296.9 48.5 1.0 1 0 0 1 1 1 1 RIB43A TPH PF13868.6 KXZ56850.1 - 3.4 6.1 70.4 1.5 7.3 20.4 3.1 3 0 0 3 3 3 0 Trichohyalin-plectin-homology domain Cpn10 PF00166.21 KXZ56851.1 - 6.5e-28 96.6 0.0 7.1e-28 96.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Vault_2 PF17794.1 KXZ56851.1 - 0.027 14.9 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Major Vault Protein repeat domain Transferase PF02458.15 KXZ56853.1 - 4.3e-08 32.2 0.0 0.00031 19.5 0.0 2.2 2 0 0 2 2 2 2 Transferase family p450 PF00067.22 KXZ56853.1 - 0.058 12.1 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 EF-hand_1 PF00036.32 KXZ56854.1 - 4.1e-19 66.6 8.7 2.1e-08 33.1 0.0 4.0 3 1 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KXZ56854.1 - 3.5e-16 59.4 3.2 1.6e-12 47.7 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXZ56854.1 - 3.1e-15 55.8 9.8 3.1e-10 39.8 2.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXZ56854.1 - 1.1e-12 46.8 3.3 2.2e-08 33.3 1.3 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KXZ56854.1 - 1.8e-10 39.8 2.7 1.4e-05 24.4 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KXZ56854.1 - 0.0044 17.3 0.1 0.22 11.9 0.0 2.1 1 1 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXZ56854.1 - 0.0089 16.3 0.6 0.06 13.7 0.1 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXZ56854.1 - 0.019 14.9 1.7 3.8 7.5 0.1 2.2 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.12 KXZ56854.1 - 0.057 12.0 0.1 0.062 11.9 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PRP38 PF03371.15 KXZ56855.1 - 2.8e-53 180.4 0.0 3.5e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family zf-CHCC PF10276.9 KXZ56856.1 - 0.00084 19.3 0.5 0.002 18.2 0.5 1.6 2 0 0 2 2 2 1 Zinc-finger domain EF-hand_1 PF00036.32 KXZ56857.1 - 1.2e-40 134.0 16.1 2.4e-10 39.2 0.3 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KXZ56857.1 - 7.6e-35 119.2 2.8 1.6e-18 66.9 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXZ56857.1 - 2.4e-31 107.3 11.0 7.6e-17 60.9 0.4 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KXZ56857.1 - 8.6e-31 103.2 9.5 1.8e-09 36.7 0.1 5.0 4 2 2 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 KXZ56857.1 - 1.8e-26 90.4 8.5 1.4e-06 27.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXZ56857.1 - 5.6e-15 55.4 0.1 2.5e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXZ56857.1 - 5.6e-09 35.9 0.9 0.00037 20.4 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXZ56857.1 - 1.8e-08 34.7 0.0 0.0011 19.2 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KXZ56857.1 - 4.4e-06 26.6 0.0 0.17 12.0 0.0 2.7 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 KXZ56857.1 - 8.8e-05 23.3 0.0 0.0091 16.9 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KXZ56857.1 - 0.00012 22.1 1.2 0.37 11.0 0.2 3.1 2 2 2 4 4 4 2 Dockerin type I domain DUF3349 PF11829.8 KXZ56857.1 - 0.00013 22.7 0.5 0.9 10.4 0.0 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) Caleosin PF05042.13 KXZ56857.1 - 0.00029 20.8 1.1 0.42 10.5 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 KXZ56857.1 - 0.0004 20.4 0.8 0.7 9.8 0.1 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF1103 PF06513.11 KXZ56857.1 - 0.0018 18.0 3.9 0.0021 17.7 3.9 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF5580 PF17743.1 KXZ56857.1 - 0.0094 14.5 0.0 0.01 14.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) dCache_2 PF08269.11 KXZ56857.1 - 0.011 14.9 0.1 0.76 8.9 0.0 2.1 1 1 0 2 2 2 0 Cache domain RNA_pol_Rpb4 PF03874.16 KXZ56857.1 - 0.014 15.8 0.5 2 8.7 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb4 Gly_acyl_tr_N PF06021.11 KXZ56857.1 - 0.041 14.0 0.0 0.085 13.0 0.0 1.5 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase MotA_activ PF09114.10 KXZ56857.1 - 0.044 13.9 0.1 0.81 9.9 0.0 2.3 2 1 0 2 2 2 0 Transcription factor MotA, activation domain SurA_N_2 PF13623.6 KXZ56857.1 - 0.061 13.2 0.6 3.1 7.7 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Phage_TAC_12 PF12363.8 KXZ56857.1 - 0.069 13.6 1.7 0.27 11.6 0.2 2.4 2 1 1 3 3 3 0 Phage tail assembly chaperone protein, TAC Peptidase_M24 PF00557.24 KXZ56857.1 - 0.072 12.8 0.1 0.97 9.1 0.0 2.2 2 0 0 2 2 2 0 Metallopeptidase family M24 Poly_export PF02563.16 KXZ56857.1 - 0.072 13.3 0.1 1.2 9.4 0.0 2.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein PLAT PF01477.23 KXZ56858.1 - 0 1013.6 48.7 1.7e-20 73.7 0.1 20.3 17 3 3 20 20 20 20 PLAT/LH2 domain ATS3 PF06232.11 KXZ56858.1 - 4.7e-40 136.4 0.0 0.0059 16.5 0.0 14.0 15 0 0 15 15 15 10 Embryo-specific protein 3, (ATS3) HELP PF03451.14 KXZ56858.1 - 1.4e-18 66.5 0.0 3.7e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KXZ56858.1 - 5.1e-17 61.9 22.4 0.0011 19.7 0.3 10.7 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56858.1 - 2.9e-11 43.5 0.2 0.00016 21.9 0.0 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Phage_tube PF04985.14 KXZ56858.1 - 0.0017 18.1 2.1 29 4.3 0.0 7.0 9 0 0 9 9 9 0 Phage tail tube protein FII Ge1_WD40 PF16529.5 KXZ56858.1 - 0.006 15.6 0.0 0.041 12.8 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WW PF00397.26 KXZ56858.1 - 0.053 13.6 4.8 0.11 12.6 0.4 3.6 3 0 0 3 3 3 0 WW domain NAC PF01849.18 KXZ56858.1 - 0.074 13.0 0.6 7.3 6.6 0.1 3.3 2 0 0 2 2 2 0 NAC domain WD40 PF00400.32 KXZ56859.1 - 7.5e-12 45.6 4.1 0.014 16.3 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ56859.1 - 0.059 13.7 0.1 1.3 9.4 0.0 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXZ56859.1 - 0.19 11.0 0.0 5 6.4 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain CENP-F_leu_zip PF10473.9 KXZ56860.1 - 2.3e-05 24.5 24.6 0.00037 20.5 10.8 3.2 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 KXZ56860.1 - 7.8e-05 22.6 14.4 7.8e-05 22.6 14.4 2.8 1 1 1 3 3 3 1 Ezrin/radixin/moesin family APG6_N PF17675.1 KXZ56860.1 - 0.00025 21.6 35.2 0.022 15.3 4.8 3.2 1 1 2 3 3 3 2 Apg6 coiled-coil region KASH_CCD PF14662.6 KXZ56860.1 - 0.00064 19.6 18.6 0.051 13.4 10.9 3.3 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH HIP1_clath_bdg PF16515.5 KXZ56860.1 - 0.0015 19.1 24.7 0.0073 16.9 1.5 4.2 3 1 1 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 TRAF_BIRC3_bd PF16673.5 KXZ56860.1 - 0.0081 15.9 7.9 0.44 10.4 0.4 2.8 2 1 0 2 2 2 2 TNF receptor-associated factor BIRC3 binding domain Laminin_II PF06009.12 KXZ56860.1 - 0.016 15.3 12.9 0.23 11.4 0.7 3.9 2 1 2 4 4 4 0 Laminin Domain II LXG PF04740.12 KXZ56860.1 - 0.034 13.9 1.1 0.072 12.8 1.1 1.6 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF1664 PF07889.12 KXZ56860.1 - 0.059 13.4 8.9 0.033 14.2 2.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CCDC144C PF14915.6 KXZ56860.1 - 0.089 11.9 18.4 0.21 10.7 0.8 2.7 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region DUF4472 PF14739.6 KXZ56860.1 - 0.14 12.9 18.8 0.38 11.5 7.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) CENP-K PF11802.8 KXZ56860.1 - 0.16 11.5 8.8 0.034 13.7 3.2 2.2 1 1 1 2 2 2 0 Centromere-associated protein K FapA PF03961.13 KXZ56860.1 - 0.18 10.4 8.6 0.85 8.2 3.2 2.3 1 1 0 2 2 2 0 Flagellar Assembly Protein A Prominin PF05478.11 KXZ56860.1 - 0.2 9.6 4.8 0.23 9.4 2.1 1.6 1 1 1 2 2 2 0 Prominin Spc7 PF08317.11 KXZ56860.1 - 0.21 10.4 24.8 4.5 6.1 7.2 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KXZ56860.1 - 0.26 10.6 18.6 0.1 11.9 10.4 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KXZ56860.1 - 0.26 10.6 21.6 6.8 5.9 21.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KXZ56860.1 - 0.29 11.2 12.0 0.067 13.2 2.4 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 KXZ56860.1 - 0.3 10.8 16.8 0.068 12.9 7.3 2.7 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Fez1 PF06818.15 KXZ56860.1 - 0.47 10.9 23.4 1.2 9.5 15.5 2.3 1 1 0 2 2 2 0 Fez1 CEP63 PF17045.5 KXZ56860.1 - 0.49 10.2 20.4 1.1 9.0 19.7 2.0 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Seryl_tRNA_N PF02403.22 KXZ56860.1 - 0.51 10.6 19.2 0.17 12.1 2.3 3.7 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 KXZ56860.1 - 0.52 10.4 17.1 1.1 9.4 1.0 3.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Tweety PF04906.13 KXZ56860.1 - 0.56 8.8 2.7 0.84 8.2 1.6 1.6 1 1 1 2 2 2 0 Tweety Nsp1_C PF05064.13 KXZ56860.1 - 0.57 10.0 5.3 0.23 11.3 1.3 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region HAP1_N PF04849.13 KXZ56860.1 - 0.64 9.2 24.2 0.069 12.3 8.4 2.7 1 1 0 2 2 2 0 HAP1 N-terminal conserved region YabA PF06156.13 KXZ56860.1 - 0.66 10.6 14.5 0.43 11.2 1.7 4.0 1 1 2 3 3 3 0 Initiation control protein YabA DUF3584 PF12128.8 KXZ56860.1 - 0.69 7.4 29.4 0.012 13.2 14.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CLZ PF16526.5 KXZ56860.1 - 0.7 10.3 22.2 0.22 11.9 2.4 4.7 2 1 3 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EzrA PF06160.12 KXZ56860.1 - 0.73 7.9 10.9 0.092 10.9 4.6 2.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Taxilin PF09728.9 KXZ56860.1 - 0.82 8.8 13.3 0.035 13.3 2.9 2.5 2 1 0 2 2 2 0 Myosin-like coiled-coil protein Cluap1 PF10234.9 KXZ56860.1 - 0.91 8.9 20.3 0.07 12.5 6.2 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF3450 PF11932.8 KXZ56860.1 - 0.94 8.7 24.8 0.1 11.9 6.6 3.6 2 1 1 4 4 4 0 Protein of unknown function (DUF3450) CR6_interact PF10147.9 KXZ56860.1 - 1 9.0 10.4 0.069 12.9 4.8 1.8 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TMPIT PF07851.13 KXZ56860.1 - 1.1 8.5 5.6 3.5 6.8 2.4 2.1 1 1 1 2 2 2 0 TMPIT-like protein Rab5-bind PF09311.11 KXZ56860.1 - 1.1 8.6 23.4 0.95 8.8 7.1 3.2 1 1 1 2 2 2 0 Rabaptin-like protein DUF724 PF05266.14 KXZ56860.1 - 1.1 9.0 15.9 0.45 10.3 1.5 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF724) Filament PF00038.21 KXZ56860.1 - 1.1 8.7 21.2 0.11 12.1 7.5 2.7 1 1 1 2 2 2 0 Intermediate filament protein AAA_13 PF13166.6 KXZ56860.1 - 1.2 7.6 13.0 0.99 8.0 6.1 2.0 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.11 KXZ56860.1 - 1.3 9.2 36.6 22 5.2 24.6 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 KXZ56860.1 - 1.7 9.6 19.1 19 6.2 0.6 4.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain PI3K_P85_iSH2 PF16454.5 KXZ56860.1 - 2.1 7.9 17.8 2.9 7.5 6.1 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Gp58 PF07902.11 KXZ56860.1 - 2.4 6.3 8.0 10 4.3 6.9 1.9 1 1 1 2 2 2 0 gp58-like protein DLP_helical PF18709.1 KXZ56860.1 - 2.5 7.2 10.4 2.2 7.4 2.6 2.8 1 1 2 3 3 3 0 Dynamin-like helical domain Bcr-Abl_Oligo PF09036.10 KXZ56860.1 - 2.6 8.1 7.8 2.5 8.1 0.5 3.5 3 1 0 4 4 3 0 Bcr-Abl oncoprotein oligomerisation domain ADIP PF11559.8 KXZ56860.1 - 2.8 8.0 27.4 0.39 10.8 9.9 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.8 KXZ56860.1 - 2.8 7.5 29.3 0.058 13.0 7.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) UPF0242 PF06785.11 KXZ56860.1 - 3 7.9 17.8 42 4.2 11.7 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 KXZ56860.1 - 3.1 8.3 5.5 10 6.6 0.2 3.7 3 2 2 5 5 4 0 Flagella accessory protein C (FlaC) IFP_35_N PF07334.13 KXZ56860.1 - 3.2 7.9 6.3 6.5 6.9 1.4 3.1 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus CALCOCO1 PF07888.11 KXZ56860.1 - 3.9 6.2 30.0 82 1.9 30.0 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4618 PF15397.6 KXZ56860.1 - 4.2 6.7 12.4 6.2 6.2 4.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) COG5 PF10392.9 KXZ56860.1 - 4.6 7.4 10.8 0.72 10.0 4.5 2.6 2 1 1 3 3 3 0 Golgi transport complex subunit 5 FAM76 PF16046.5 KXZ56860.1 - 5.3 6.3 12.4 0.42 9.9 0.3 2.4 1 1 0 2 2 2 0 FAM76 protein Sec34 PF04136.15 KXZ56860.1 - 5.4 6.9 10.9 2.6 7.9 0.5 2.9 2 1 1 3 3 3 0 Sec34-like family TMF_TATA_bd PF12325.8 KXZ56860.1 - 5.6 7.2 29.5 1.2 9.3 10.0 3.9 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CorA PF01544.18 KXZ56860.1 - 5.7 6.2 14.8 1.2 8.4 1.4 2.3 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.20 KXZ56860.1 - 6.2 6.8 18.6 2.7 8.0 3.9 4.4 2 2 2 4 4 4 0 Prefoldin subunit Cep57_MT_bd PF06657.13 KXZ56860.1 - 8.1 7.0 21.6 0.15 12.6 1.5 5.0 2 2 4 6 6 6 0 Centrosome microtubule-binding domain of Cep57 FmiP_Thoc5 PF09766.9 KXZ56860.1 - 9 5.5 17.8 2.1 7.5 9.3 3.1 2 1 0 2 2 2 0 Fms-interacting protein/Thoc5 YlqD PF11068.8 KXZ56860.1 - 9.9 6.6 18.1 0.89 9.9 4.4 3.1 1 1 2 3 3 3 0 YlqD protein Sipho_Gp157 PF05565.11 KXZ56860.1 - 9.9 6.2 13.2 0.79 9.7 3.3 2.9 1 1 2 3 3 3 0 Siphovirus Gp157 Tom37 PF10568.9 KXZ56862.1 - 1.5e-25 89.9 0.1 2.6e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KXZ56862.1 - 6.2e-17 62.2 0.0 1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXZ56862.1 - 2.6e-07 30.3 0.0 6e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXZ56862.1 - 7.8e-07 29.0 0.2 2.9e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXZ56862.1 - 0.0062 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NTP_transf_9 PF04248.12 KXZ56863.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) PK PF00224.21 KXZ56864.1 - 4.7e-76 255.9 0.0 6.9e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXZ56864.1 - 1.6e-16 60.6 0.0 4.4e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain zf-CW PF07496.15 KXZ56864.1 - 5.1e-07 29.6 5.9 8.8e-07 28.9 5.9 1.3 1 0 0 1 1 1 1 CW-type Zinc Finger DPBB_1 PF03330.18 KXZ56865.1 - 2.5e-09 37.3 0.1 4.2e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase Herpes_capsid PF06112.11 KXZ56865.1 - 0.39 10.8 4.1 0.57 10.2 4.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DPBB_1 PF03330.18 KXZ56866.1 - 4.5e-09 36.5 0.1 7.1e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Lytic transglycolase MCC-bdg_PDZ PF10506.9 KXZ56867.1 - 0.2 11.7 7.8 0.086 12.9 2.8 3.1 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome RWP-RK PF02042.15 KXZ56868.1 - 2.9e-21 75.2 0.1 3.5e-20 71.7 0.2 2.5 2 0 0 2 2 2 1 RWP-RK domain HTH_17 PF12728.7 KXZ56868.1 - 0.16 12.2 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1980 PF09323.10 KXZ56868.1 - 2.4 8.0 10.6 7.5 6.4 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Fungal_trans_2 PF11951.8 KXZ56868.1 - 9.4 4.9 15.1 2.9 6.6 5.6 2.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain Ank_2 PF12796.7 KXZ56869.1 - 7.1e-127 414.3 35.5 1.6e-15 57.4 0.0 8.4 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 KXZ56869.1 - 6.5e-68 222.4 52.8 1.3e-05 25.4 0.1 16.7 17 0 0 17 17 17 14 Ankyrin repeat Ank_5 PF13857.6 KXZ56869.1 - 2.6e-64 212.5 30.4 2.1e-08 34.3 0.1 11.7 6 4 6 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56869.1 - 4.1e-64 204.9 19.9 0.00082 19.7 0.0 16.7 17 0 0 17 17 17 15 Ankyrin repeat Ank_4 PF13637.6 KXZ56869.1 - 2.6e-63 209.6 17.4 3.4e-10 40.2 0.0 12.2 4 3 12 16 16 16 14 Ankyrin repeats (many copies) Nitro_FeMo-Co PF02579.17 KXZ56869.1 - 0.063 13.6 0.1 0.063 13.6 0.1 3.5 5 0 0 5 5 5 0 Dinitrogenase iron-molybdenum cofactor FAD_binding_4 PF01565.23 KXZ56870.1 - 3.1e-13 49.7 0.1 6.7e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXZ56870.1 - 2.7e-05 24.1 0.0 5.7e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase GRASP55_65 PF04495.14 KXZ56870.1 - 0.0041 17.4 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain MatE PF01554.18 KXZ56871.1 - 2.5e-10 40.2 25.9 7e-07 29.0 0.8 3.0 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KXZ56871.1 - 0.0043 17.1 14.8 0.0043 17.1 14.8 3.9 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain TB2_DP1_HVA22 PF03134.19 KXZ56872.1 - 9.2e-16 57.5 1.0 1.6e-15 56.8 1.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Cupin_8 PF13621.6 KXZ56873.1 - 9.4e-19 68.1 0.0 1.9e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Cupin-like domain JmjC PF02373.22 KXZ56873.1 - 2e-13 50.7 0.1 1e-12 48.5 0.1 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase EKLF_TAD1 PF16832.5 KXZ56873.1 - 0.028 14.3 0.1 0.11 12.4 0.1 2.1 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 TIP120 PF08623.10 KXZ56874.1 - 4.5e-54 182.7 0.1 6.9e-53 178.9 0.0 3.0 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KXZ56874.1 - 0.0083 16.5 42.6 0.011 16.1 0.9 8.9 5 3 5 10 10 10 5 HEAT repeats Cnd1 PF12717.7 KXZ56874.1 - 0.013 15.6 0.0 7.7 6.5 0.0 4.2 6 0 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KXZ56874.1 - 0.054 12.7 0.0 18 4.4 0.0 3.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KXZ56874.1 - 0.067 13.5 32.1 0.46 10.9 0.2 10.4 10 1 0 10 10 10 0 HEAT repeat HEAT_EZ PF13513.6 KXZ56874.1 - 0.072 13.6 0.2 0.072 13.6 0.2 11.8 12 3 3 15 15 15 0 HEAT-like repeat DUF4033 PF13225.6 KXZ56875.1 - 2.2e-32 110.9 0.4 2.9e-32 110.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) DPBB_1 PF03330.18 KXZ56876.1 - 3e-09 37.0 0.0 5.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Lytic transglycolase Adeno_E3_14_5 PF04834.12 KXZ56876.1 - 0.095 13.3 0.1 0.57 10.8 0.1 2.1 2 0 0 2 2 2 0 Early E3 14.5 kDa protein RRM_1 PF00076.22 KXZ56877.1 - 6.3e-51 170.1 0.0 3.1e-15 55.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXZ56877.1 - 3.2e-09 36.8 0.2 0.0074 16.4 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 KXZ56877.1 - 1.5e-08 34.3 0.0 0.00023 20.7 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXZ56877.1 - 3.5e-07 30.0 0.0 0.0025 17.6 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXZ56877.1 - 0.027 14.5 0.0 8.4 6.5 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF4280 PF14107.6 KXZ56877.1 - 0.075 13.8 0.0 18 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4280) RETICULATA-like PF11891.8 KXZ56878.1 - 1.5e-63 213.8 0.0 1.9e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein RETICULATA-related FoP_duplication PF13865.6 KXZ56878.1 - 7.4 7.2 7.7 13 6.4 7.7 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Guanylate_cyc PF00211.20 KXZ56879.1 - 1.9e-07 30.9 0.1 0.00073 19.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SBP_bac_1 PF01547.25 KXZ56879.1 - 0.00011 22.2 0.7 0.00023 21.2 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein Phenol_monoox PF04663.12 KXZ56879.1 - 0.23 11.7 0.5 0.95 9.6 0.3 2.2 2 0 0 2 2 2 0 Phenol hydroxylase conserved region WD40 PF00400.32 KXZ56881.1 - 1.8e-07 31.7 18.7 0.26 12.2 0.0 9.2 11 0 0 11 11 11 3 WD domain, G-beta repeat HELP PF03451.14 KXZ56881.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 HELP motif ANAPC4_WD40 PF12894.7 KXZ56881.1 - 0.035 14.4 0.0 1.6 9.0 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXZ56881.1 - 0.036 14.6 6.2 2.2 8.9 0.0 5.2 5 0 0 5 5 5 0 PQQ-like domain Biotin_lipoyl PF00364.22 KXZ56882.1 - 8.8e-13 47.9 5.4 1.2e-12 47.4 5.4 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 KXZ56882.1 - 0.00055 19.8 0.5 0.0011 18.8 0.5 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 KXZ56882.1 - 0.0043 16.8 4.0 0.012 15.5 0.5 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXZ56882.1 - 0.072 13.8 5.0 0.16 12.7 1.1 2.4 2 1 0 2 2 2 0 HlyD family secretion protein RnfC_N PF13375.6 KXZ56882.1 - 0.37 10.8 4.2 1.4 8.9 0.5 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Retinal PF15449.6 KXZ56882.1 - 1.1 6.9 7.6 1.2 6.8 7.6 1.0 1 0 0 1 1 1 0 Retinal protein BACK PF07707.15 KXZ56883.1 - 0.00054 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Hydrolase PF00702.26 KXZ56885.1 - 7.2e-15 55.8 0.0 1.4e-11 45.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXZ56885.1 - 6.5e-14 52.4 0.0 9.8e-12 45.3 0.0 2.1 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXZ56885.1 - 2.7e-10 40.2 0.0 4.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXZ56885.1 - 3.2e-07 31.0 0.1 0.00051 20.5 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXZ56885.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KXZ56885.1 - 0.0018 17.9 0.0 0.047 13.3 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_3 PF08282.12 KXZ56885.1 - 0.055 13.2 0.0 6.1 6.5 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXZ56885.1 - 0.16 11.4 0.0 0.46 10.0 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase TauE PF01925.19 KXZ56886.1 - 1.4e-06 28.2 7.1 1.9e-06 27.7 7.1 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Thioredoxin PF00085.20 KXZ56887.1 - 8.2e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KXZ56887.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosducin Kelch_1 PF01344.25 KXZ56888.1 - 8.2e-39 130.9 11.3 5.8e-12 45.0 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KXZ56888.1 - 4.2e-22 77.6 5.2 3.6e-05 23.9 0.1 6.8 5 2 2 7 7 7 5 Kelch motif Kelch_5 PF13854.6 KXZ56888.1 - 7.2e-22 76.9 9.0 9.9e-06 25.4 0.1 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KXZ56888.1 - 8.6e-21 73.7 5.7 0.00035 20.5 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KXZ56888.1 - 5.1e-15 54.8 4.1 0.021 14.8 0.0 6.6 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 KXZ56888.1 - 6.1e-13 48.7 9.0 0.033 14.5 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain tRNA_bind_2 PF13725.6 KXZ56890.1 - 2.8e-34 118.9 0.0 3.5e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 KXZ56891.1 - 1.6e-30 104.9 0.0 2.5e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) FAST_1 PF06743.15 KXZ56892.1 - 0.00066 19.6 0.0 0.17 11.8 0.0 4.0 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 1 TetR_C_15 PF17918.1 KXZ56892.1 - 0.24 12.2 0.1 0.24 12.2 0.1 5.9 7 0 0 7 7 7 0 Tetracyclin repressor-like, C-terminal domain TK PF00265.18 KXZ56894.1 - 7.3e-50 169.3 0.0 8.5e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_22 PF13401.6 KXZ56894.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXZ56894.1 - 0.021 14.6 1.3 0.036 13.8 1.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXZ56894.1 - 0.037 14.1 0.0 0.16 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF1963 PF09234.10 KXZ56895.1 - 1.8e-10 41.7 0.0 3.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) Cupin_8 PF13621.6 KXZ56896.1 - 1.5e-46 159.2 0.0 1.9e-22 80.2 0.0 3.2 2 1 0 2 2 2 2 Cupin-like domain AAA_23 PF13476.6 KXZ56897.1 - 6.6e-29 101.8 0.1 8.2e-27 95.0 0.0 2.6 2 1 1 3 3 3 1 AAA domain SMC_N PF02463.19 KXZ56897.1 - 5.1e-07 29.4 0.2 1.1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXZ56897.1 - 7.8e-05 22.6 0.1 0.00012 21.9 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KXZ56897.1 - 0.00031 20.7 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KXZ56897.1 - 0.0012 19.4 0.0 0.0042 17.6 0.0 2.0 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 KXZ56897.1 - 0.0039 16.5 0.1 0.17 11.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_13 PF13166.6 KXZ56897.1 - 0.021 13.5 0.0 0.021 13.5 0.0 3.0 3 1 1 4 4 4 0 AAA domain AAA_29 PF13555.6 KXZ56897.1 - 0.025 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain XS PF03468.14 KXZ56897.1 - 0.035 14.4 0.0 0.084 13.2 0.0 1.7 1 0 0 1 1 1 0 XS domain AAA_22 PF13401.6 KXZ56897.1 - 0.098 12.9 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXZ56897.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Yuri_gagarin PF15934.5 KXZ56897.1 - 0.17 11.7 3.1 0.36 10.6 2.5 1.8 1 1 0 1 1 1 0 Yuri gagarin cobW PF02492.19 KXZ56897.1 - 0.17 11.5 0.2 0.38 10.3 0.2 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NPV_P10 PF05531.12 KXZ56897.1 - 0.2 12.1 0.0 1 9.9 0.0 2.2 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KXZ56897.1 - 0.26 11.6 5.9 0.18 12.1 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) AAA_16 PF13191.6 KXZ56897.1 - 0.38 11.1 0.0 0.38 11.1 0.0 4.0 2 1 0 2 2 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KXZ56897.1 - 2.7 7.3 8.1 32 3.8 0.0 3.5 3 1 1 4 4 4 0 FtsK/SpoIIIE family Fez1 PF06818.15 KXZ56897.1 - 8.3 6.8 20.5 2.1 8.8 10.5 2.6 2 1 0 2 2 2 0 Fez1 DUF2477 PF10631.9 KXZ56898.1 - 0.019 15.6 0.3 0.046 14.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) CBM_20 PF00686.19 KXZ56901.1 - 8.5e-29 99.3 0.0 1.2e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Starch binding domain CENP-F_leu_zip PF10473.9 KXZ56901.1 - 0.0016 18.4 8.4 0.034 14.2 3.7 2.3 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KXZ56901.1 - 0.032 13.1 8.4 0.029 13.3 1.7 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein EzrA PF06160.12 KXZ56901.1 - 0.046 11.9 2.4 0.054 11.7 0.2 1.8 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 KXZ56901.1 - 0.092 12.1 10.9 0.19 11.1 10.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KXZ56901.1 - 0.093 13.3 11.9 1.7 9.1 1.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF812 PF05667.11 KXZ56901.1 - 0.11 11.4 6.4 0.29 10.0 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 KXZ56901.1 - 0.12 12.8 0.1 23 5.5 0.0 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 KXZ56901.1 - 0.38 10.8 3.7 1.7 8.7 0.2 2.5 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 KXZ56901.1 - 0.48 10.5 16.2 3 7.9 5.0 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.6 KXZ56901.1 - 0.89 9.7 14.8 4.6 7.4 3.4 2.6 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit BRE1 PF08647.11 KXZ56901.1 - 1.2 9.2 5.3 2.9 8.0 0.5 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF5339 PF17274.2 KXZ56901.1 - 1.3 10.0 4.4 2.5 9.0 0.5 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5339) DUF4140 PF13600.6 KXZ56901.1 - 1.4 9.4 9.8 3.8 8.0 0.3 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) CC2-LZ PF16516.5 KXZ56901.1 - 1.7 9.1 6.5 3.8 7.9 0.2 2.9 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator THOC7 PF05615.13 KXZ56901.1 - 1.8 8.9 14.4 0.15 12.3 5.1 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 TMF_TATA_bd PF12325.8 KXZ56901.1 - 1.9 8.7 11.3 5.8 7.2 3.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KXZ56901.1 - 2.4 8.5 11.9 1.5 9.3 2.1 2.2 1 1 1 2 2 2 0 Fez1 Bap31_Bap29_C PF18035.1 KXZ56901.1 - 2.5 8.1 5.4 0.43 10.6 0.2 2.4 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4404 PF14357.6 KXZ56901.1 - 4.5 8.0 7.1 2.3 8.9 0.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) ATG16 PF08614.11 KXZ56901.1 - 6 7.0 15.5 40 4.3 14.7 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Ank_2 PF12796.7 KXZ56902.1 - 2.4e-10 40.9 5.6 0.009 16.6 0.3 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXZ56902.1 - 3.6e-08 33.8 7.7 0.013 16.1 1.2 5.3 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXZ56902.1 - 8.3e-06 25.8 8.2 2.3 9.1 0.1 6.1 6 1 1 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KXZ56902.1 - 0.00066 19.9 12.2 0.87 10.0 0.2 5.4 4 2 2 6 6 6 2 Ankyrin repeats (many copies) GST_N_5 PF18485.1 KXZ56902.1 - 0.087 13.2 1.9 0.18 12.2 0.3 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Ank PF00023.30 KXZ56902.1 - 0.62 10.6 6.8 34 5.1 0.1 4.2 3 1 1 4 4 4 0 Ankyrin repeat RimM PF01782.18 KXZ56903.1 - 1.1e-15 57.5 0.1 3.7e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 RimM N-terminal domain PRC PF05239.16 KXZ56903.1 - 2.5e-08 33.9 0.0 5.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 PRC-barrel domain DUF4746 PF15928.5 KXZ56903.1 - 0.024 14.1 3.7 0.035 13.6 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ribosomal_L35Ae PF01247.18 KXZ56903.1 - 0.074 13.2 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L35Ae DUF4372 PF14294.6 KXZ56903.1 - 0.18 12.0 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) Myc_N PF01056.18 KXZ56903.1 - 0.2 11.5 0.9 0.29 11.0 0.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 KXZ56903.1 - 4 5.4 9.2 5.5 5.0 9.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi ANAPC4_WD40 PF12894.7 KXZ56904.1 - 0.00012 22.4 1.9 4.9 7.5 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UCH PF00443.29 KXZ56905.1 - 7.5e-40 137.0 0.0 1.6e-39 136.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXZ56905.1 - 5.5e-19 68.9 0.0 1.2e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase adh_short_C2 PF13561.6 KXZ56906.1 - 1.4e-62 211.4 0.1 1.7e-62 211.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXZ56906.1 - 5.5e-54 182.6 0.0 6.9e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXZ56906.1 - 2.2e-09 37.5 0.0 3.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXZ56906.1 - 0.0094 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXZ56906.1 - 0.028 13.9 0.1 0.33 10.4 0.1 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KXZ56906.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.15 KXZ56906.1 - 0.16 11.8 0.8 0.52 10.1 0.4 2.0 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein LRR_4 PF12799.7 KXZ56907.1 - 1.8e-11 44.1 3.7 0.00034 20.9 0.2 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXZ56907.1 - 2.6e-06 27.0 0.0 3.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KXZ56907.1 - 3.1e-05 23.6 5.8 0.0054 16.5 1.0 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KXZ56907.1 - 0.065 13.3 3.0 0.72 10.1 0.3 2.9 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 KXZ56907.1 - 6.1 7.8 6.6 23 6.0 0.2 3.8 4 1 0 4 4 4 0 Leucine Rich Repeat LON_substr_bdg PF02190.16 KXZ56908.1 - 9.3e-08 32.2 0.0 0.0001 22.3 0.0 2.1 2 0 0 2 2 2 2 ATP-dependent protease La (LON) substrate-binding domain DUF5631 PF18645.1 KXZ56908.1 - 0.055 13.9 1.0 0.18 12.2 1.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5631) Mito_fiss_reg PF05308.11 KXZ56908.1 - 1.4 8.9 4.5 2.8 8.0 4.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.25 KXZ56909.1 - 1.1e-26 93.8 0.0 1.7e-19 70.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56909.1 - 1.2e-24 87.1 0.0 3e-20 72.6 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXZ56909.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF4287 PF14117.6 KXZ56909.1 - 0.14 12.3 0.6 0.33 11.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Thymidylate_kin PF02223.17 KXZ56910.1 - 1.4e-50 171.6 0.0 1.5e-24 86.7 0.0 2.0 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.6 KXZ56910.1 - 8.8e-06 26.1 0.2 0.0081 16.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain ECH_1 PF00378.20 KXZ56911.1 - 3.4e-41 141.2 0.0 4.3e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXZ56911.1 - 3.2e-15 56.5 0.0 3.9e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PhoD PF09423.10 KXZ56912.1 - 1.1e-06 27.9 0.4 4.9e-06 25.8 0.2 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Ras PF00071.22 KXZ56914.1 - 4e-51 172.8 0.0 4.8e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ56914.1 - 2.7e-30 105.1 0.0 4.7e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ56914.1 - 2.5e-10 40.1 0.0 3.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KXZ56914.1 - 0.00011 22.5 0.1 0.00066 20.0 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KXZ56914.1 - 0.00081 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KXZ56914.1 - 0.03 13.5 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 KXZ56914.1 - 0.051 13.3 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXZ56914.1 - 0.063 13.2 0.0 13 5.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 KXZ56914.1 - 0.084 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein TsaE PF02367.17 KXZ56914.1 - 0.099 12.7 0.0 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KXZ56914.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KXZ56914.1 - 0.17 11.2 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 KaiC DUF4520 PF15016.6 KXZ56915.1 - 3.5e-18 65.5 0.0 5.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) DUF4524 PF15025.6 KXZ56916.1 - 2.1e-33 115.1 0.0 3.3e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4524) Thioredoxin_7 PF13899.6 KXZ56917.1 - 7.7e-13 48.4 0.0 1.8e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KXZ56917.1 - 1.3e-11 44.1 0.6 2.4e-11 43.2 0.6 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXZ56917.1 - 5.2e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 KXZ56917.1 - 0.00033 20.4 2.8 0.0013 18.5 2.8 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif dsrm PF00035.26 KXZ56918.1 - 1.6e-07 31.9 0.0 9.9e-06 26.2 0.0 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 KXZ56918.1 - 0.00042 20.4 0.1 0.0015 18.7 0.1 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain dsRBD2 PF17842.1 KXZ56918.1 - 0.23 11.6 0.0 0.53 10.5 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Pkinase PF00069.25 KXZ56920.1 - 1.2e-33 116.6 0.0 2.8e-31 108.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56920.1 - 2.3e-31 109.0 0.0 3.4e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXZ56920.1 - 0.0028 17.6 0.1 0.0051 16.8 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC_tran PF00005.27 KXZ56921.1 - 1.3e-24 87.3 0.0 4.2e-24 85.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 KXZ56921.1 - 5.7e-11 42.1 0.4 8.7e-11 41.5 0.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXZ56921.1 - 5.9e-10 39.4 0.0 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXZ56921.1 - 0.037 13.8 0.1 0.096 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KXZ56921.1 - 0.074 13.3 0.0 0.86 9.9 0.0 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane PF01061.24 KXZ56921.1 - 0.12 11.8 1.6 0.25 10.7 0.6 1.9 2 0 0 2 2 2 0 ABC-2 type transporter SMC_N PF02463.19 KXZ56921.1 - 0.15 11.5 0.0 16 4.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 KXZ56922.1 - 3.5e-13 50.2 0.3 2.8e-11 44.1 0.3 2.2 1 1 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXZ56922.1 - 2.4e-08 33.5 3.8 3.5e-08 33.0 3.8 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXZ56922.1 - 0.00012 22.0 0.2 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXZ56922.1 - 0.11 11.9 0.0 0.93 8.9 0.0 1.8 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain HD PF01966.22 KXZ56927.1 - 1.3e-07 31.8 0.2 4e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 HD domain RabGAP-TBC PF00566.18 KXZ56929.1 - 2.2e-11 43.8 0.0 1.3e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_31 PF01055.26 KXZ56930.1 - 3.4e-136 454.9 0.8 4.2e-136 454.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXZ56930.1 - 3.8e-22 78.4 1.4 1.9e-20 73.0 0.1 3.3 2 1 1 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 KXZ56930.1 - 8.2e-06 26.0 0.0 2.3e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NtCtMGAM_N PF16863.5 KXZ56930.1 - 8.5e-05 22.7 0.1 0.00025 21.2 0.1 1.8 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase RabGAP-TBC PF00566.18 KXZ56931.1 - 1.8e-30 106.2 0.0 8.9e-29 100.7 0.0 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Med14 PF08638.11 KXZ56932.1 - 8.9e-28 97.0 0.0 1.5e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 tRNA-synt_2b PF00587.25 KXZ56933.1 - 1.2e-35 123.1 0.0 7e-35 120.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXZ56933.1 - 1.7e-27 95.8 4.5 3.5e-27 94.7 4.5 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 KXZ56933.1 - 0.0032 17.7 3.9 0.0056 16.9 3.9 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 KXZ56933.1 - 0.0047 17.1 2.9 0.0047 17.1 2.9 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Lipoprotein_7 PF01540.16 KXZ56933.1 - 0.02 14.2 1.6 0.03 13.6 1.6 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Com_YlbF PF06133.11 KXZ56933.1 - 0.079 13.6 3.0 0.19 12.4 3.0 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA SecA_DEAD PF07517.14 KXZ56933.1 - 0.094 12.0 0.2 0.23 10.7 0.1 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain Phage_GP20 PF06810.11 KXZ56933.1 - 0.098 12.5 4.8 0.17 11.6 4.8 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4407 PF14362.6 KXZ56933.1 - 0.17 11.2 0.8 0.26 10.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MutS_IV PF05190.18 KXZ56933.1 - 0.28 11.5 1.8 0.42 11.0 0.4 1.9 2 0 0 2 2 2 0 MutS family domain IV NUDIX PF00293.28 KXZ56934.1 - 1.7e-38 131.6 0.0 7.1e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain T2SSM_b PF10741.9 KXZ56934.1 - 0.041 13.7 0.2 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF3747 PF12565.8 KXZ56934.1 - 0.1 12.0 0.0 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3747) Zip PF02535.22 KXZ56935.1 - 2.6e-24 86.1 3.7 4e-24 85.4 3.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Tubulin PF00091.25 KXZ56936.1 - 2.6e-50 171.4 0.0 4.7e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 KXZ56936.1 - 0.082 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain JmjN PF02375.17 KXZ56936.1 - 0.1 12.6 0.1 0.39 10.7 0.0 2.0 3 0 0 3 3 3 0 jmjN domain Tubulin_2 PF13809.6 KXZ56936.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Mpv17_PMP22 PF04117.12 KXZ56936.1 - 0.17 12.1 0.0 0.48 10.7 0.0 1.7 2 0 0 2 2 2 0 Mpv17 / PMP22 family Glyco_hydro_99 PF16317.5 KXZ56938.1 - 5.5e-98 328.3 0.0 6.6e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 KXZ56938.1 - 0.0021 17.6 0.0 0.032 13.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase WbsX SNF2_N PF00176.23 KXZ56939.1 - 3.2e-52 177.4 0.0 5.4e-52 176.6 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KXZ56939.1 - 2.6e-11 43.8 0.0 4.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXZ56939.1 - 6.8e-05 22.7 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.9 KXZ56939.1 - 0.0075 16.6 0.3 0.015 15.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Methyltransf_24 PF13578.6 KXZ56939.1 - 0.16 13.0 0.0 0.4 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Helicase_C PF00271.31 KXZ56940.1 - 8.3e-07 29.3 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF962 PF06127.11 KXZ56941.1 - 2.1e-29 101.4 0.1 2.5e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) MMR_HSR1 PF01926.23 KXZ56942.1 - 6.1e-07 29.5 0.0 1.7e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXZ56942.1 - 0.042 13.8 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 KXZ56942.1 - 0.067 12.7 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXZ56942.1 - 0.16 12.0 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Dynamin family AAA_15 PF13175.6 KXZ56942.1 - 0.37 10.5 0.0 0.52 10.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain N2227 PF07942.12 KXZ56943.1 - 4.7e-71 239.2 0.0 1.2e-69 234.5 0.0 2.1 1 1 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KXZ56943.1 - 0.047 14.3 0.0 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain NAPRTase PF04095.16 KXZ56944.1 - 1.1e-36 126.6 0.0 1.4e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family kleA_kleC PF17383.2 KXZ56944.1 - 0.14 12.5 0.0 0.6 10.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DEAD PF00270.29 KXZ56945.1 - 9.9e-35 119.9 0.0 8.4e-34 116.8 0.0 2.1 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ56945.1 - 2.6e-23 82.5 0.0 4.8e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 KXZ56945.1 - 9.2e-22 77.4 0.0 1.6e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 SPRY domain PAP_fibrillin PF04755.12 KXZ56946.1 - 4.5e-24 85.5 0.0 8.1e-24 84.7 0.0 1.4 1 1 0 1 1 1 1 PAP_fibrillin PsbQ PF05757.11 KXZ56946.1 - 0.088 12.5 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) PAP_fibrillin PF04755.12 KXZ56947.1 - 6.5e-41 140.5 0.0 1e-38 133.3 0.0 2.1 1 1 0 1 1 1 1 PAP_fibrillin Rhomboid PF01694.22 KXZ56948.1 - 3.7e-26 91.9 4.7 3.7e-26 91.9 4.7 1.9 2 0 0 2 2 2 1 Rhomboid family DEAD PF00270.29 KXZ56949.1 - 1.4e-39 135.7 0.0 2.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ56949.1 - 2.2e-22 79.5 0.0 3.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXZ56949.1 - 4.6e-16 58.8 0.1 9.1e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXZ56949.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXZ56949.1 - 0.03 14.6 0.2 0.11 12.7 0.2 2.0 2 1 0 2 2 2 0 AAA domain Snf7 PF03357.21 KXZ56950.1 - 7e-12 45.3 15.3 8.8e-12 45.0 15.3 1.2 1 0 0 1 1 1 1 Snf7 IML1 PF12257.8 KXZ56950.1 - 0.0043 16.2 1.6 0.0053 15.9 1.6 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Ist1 PF03398.14 KXZ56950.1 - 0.029 14.3 8.2 0.041 13.8 8.2 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 KXZ56950.1 - 0.049 13.3 0.3 0.082 12.5 0.3 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase EIIBC-GUT_N PF03612.14 KXZ56951.1 - 0.035 13.9 2.2 0.046 13.5 2.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Suf PF05843.14 KXZ56951.1 - 0.097 12.6 8.7 0.1 12.6 8.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 KXZ56951.1 - 0.68 9.9 28.7 0.74 9.7 28.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 KXZ56951.1 - 1.2 10.1 8.8 2 9.5 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 KXZ56951.1 - 1.7 9.3 18.5 2.2 8.9 18.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 KXZ56951.1 - 2.8 6.6 7.7 3.1 6.5 7.7 1.1 1 0 0 1 1 1 0 Presenilin ABC2_membrane_2 PF12679.7 KXZ56951.1 - 3.4 6.9 5.1 4.7 6.4 5.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein T2SSC PF11356.8 KXZ56951.1 - 4 7.3 9.6 6.4 6.7 9.6 1.3 1 0 0 1 1 1 0 Type II secretion system protein C Spt20 PF12090.8 KXZ56951.1 - 5.2 6.6 32.8 6.9 6.2 32.8 1.2 1 0 0 1 1 1 0 Spt20 family Rubredoxin PF00301.20 KXZ56953.1 - 1.3e-16 60.4 6.1 1.8e-16 59.8 6.1 1.3 1 0 0 1 1 1 1 Rubredoxin TF_Zn_Ribbon PF08271.12 KXZ56953.1 - 0.0078 15.7 2.0 2.8 7.5 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KXZ56953.1 - 0.017 14.5 4.3 0.76 9.3 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_2 PF13696.6 KXZ56953.1 - 0.045 13.6 0.6 0.099 12.5 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle HypA PF01155.19 KXZ56953.1 - 0.056 13.5 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KXZ56953.1 - 0.062 13.3 0.1 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.6 KXZ56953.1 - 4 7.6 5.5 1.6 8.9 0.1 2.4 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 PAP_fibrillin PF04755.12 KXZ56954.1 - 5.2e-42 144.0 0.0 5.9e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 PAP_fibrillin Ras PF00071.22 KXZ56955.1 - 8.4e-63 210.8 0.6 9.9e-63 210.6 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXZ56955.1 - 6.9e-36 123.1 0.1 1.1e-35 122.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXZ56955.1 - 4.5e-13 49.0 0.1 6.1e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXZ56955.1 - 2.8e-07 30.6 0.1 5.6e-07 29.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXZ56955.1 - 1e-05 25.2 0.2 3.9e-05 23.3 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXZ56955.1 - 2.9e-05 24.0 0.3 0.019 14.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase DLIC PF05783.11 KXZ56955.1 - 0.0015 17.5 0.1 0.43 9.4 0.0 2.1 1 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 KXZ56955.1 - 0.0028 17.9 0.1 0.057 13.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KXZ56955.1 - 0.0031 16.9 0.1 0.0044 16.4 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KXZ56955.1 - 0.0085 15.6 0.1 0.022 14.3 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KXZ56955.1 - 0.012 16.0 0.1 0.021 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KXZ56955.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KXZ56955.1 - 0.015 14.7 0.1 0.028 13.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KXZ56955.1 - 0.018 15.6 0.1 0.027 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KXZ56955.1 - 0.019 15.0 0.2 0.06 13.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KXZ56955.1 - 0.028 14.1 0.2 0.11 12.3 0.0 2.0 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KXZ56955.1 - 0.054 13.4 0.0 1.7 8.5 0.0 2.2 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 MCM PF00493.23 KXZ56955.1 - 0.067 12.3 0.0 0.24 10.5 0.0 1.8 1 1 0 2 2 2 0 MCM P-loop domain TniB PF05621.11 KXZ56955.1 - 0.089 12.2 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 KXZ56955.1 - 0.11 12.4 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXZ56955.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FAD-SLDH PF12318.8 KXZ56955.1 - 0.17 11.9 0.1 0.35 10.9 0.0 1.5 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase MMADHC PF10229.9 KXZ56956.1 - 2.5e-18 66.8 0.0 2.8e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein MMS1_N PF10433.9 KXZ56957.1 - 0.015 14.0 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXZ56957.1 - 0.29 10.4 0.0 0.44 9.8 0.0 1.2 1 0 0 1 1 1 0 CPSF A subunit region GRAM PF02893.20 KXZ56958.1 - 0.058 13.3 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 GRAM domain DUF647 PF04884.14 KXZ56959.1 - 1.6e-56 191.6 1.6 2.4e-56 191.1 1.6 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TPR_2 PF07719.17 KXZ56962.1 - 4.7e-11 41.9 2.6 0.00018 21.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ56962.1 - 3.9e-08 32.8 1.0 0.0086 15.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ56962.1 - 4.9e-08 33.4 1.2 1.3e-06 28.8 0.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ56962.1 - 2.3e-06 27.6 0.3 0.84 10.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXZ56962.1 - 4.1e-06 27.0 0.5 4.1e-06 27.0 0.5 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ56962.1 - 6.2e-05 22.7 10.7 0.16 12.1 0.1 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ56962.1 - 0.0021 18.7 1.6 0.0021 18.7 1.6 4.2 4 2 1 5 5 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ56962.1 - 0.0021 18.1 0.1 0.28 11.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXZ56962.1 - 0.0035 17.5 2.7 0.0064 16.7 0.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXZ56962.1 - 0.005 16.7 16.5 0.0091 15.8 0.1 4.8 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ56962.1 - 0.0058 16.3 0.1 0.069 12.8 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 KXZ56962.1 - 0.019 15.8 23.9 0.026 15.3 0.1 5.3 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXZ56962.1 - 0.067 13.8 0.2 0.067 13.8 0.2 4.9 6 0 0 6 6 2 0 Tetratricopeptide repeat ChAPs PF09295.10 KXZ56962.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) D5_N PF08706.11 KXZ56962.1 - 0.15 12.4 3.7 0.27 11.5 3.7 1.4 1 0 0 1 1 1 0 D5 N terminal like TPR_6 PF13174.6 KXZ56962.1 - 1.5 9.7 6.5 2.3 9.0 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat U79_P34 PF03064.16 KXZ56962.1 - 1.9 7.8 8.9 3.4 6.9 8.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF953 PF06110.11 KXZ56963.1 - 1.9e-14 53.3 0.0 4.4e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 KXZ56963.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF179 PF02622.15 KXZ56964.1 - 2e-30 105.9 0.0 2.6e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 HAT_KAT11 PF08214.11 KXZ56965.1 - 1e-28 100.7 0.0 2.2e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Histone acetylation protein zf-TAZ PF02135.16 KXZ56965.1 - 3.3e-24 85.1 51.7 1.1e-13 51.5 16.9 3.8 3 0 0 3 3 3 2 TAZ zinc finger PHD PF00628.29 KXZ56965.1 - 1.1e-05 25.2 4.2 1.1e-05 25.2 4.2 5.2 3 2 0 3 3 3 1 PHD-finger ZZ PF00569.17 KXZ56965.1 - 7.4e-05 22.5 5.5 7.4e-05 22.5 5.5 3.6 4 0 0 4 4 4 1 Zinc finger, ZZ type Baculo_ME53 PF06061.11 KXZ56965.1 - 0.0041 16.4 0.1 0.0097 15.2 0.1 1.6 1 0 0 1 1 1 1 Baculoviridae ME53 CPP1-like PF11833.8 KXZ56966.1 - 1.3e-24 87.0 0.3 1.5e-24 86.8 0.3 1.1 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SpoIIM PF01944.17 KXZ56966.1 - 0.033 14.2 0.9 0.033 14.2 0.9 1.6 2 0 0 2 2 2 0 Stage II sporulation protein M eIF2A PF08662.11 KXZ56967.1 - 4.2e-60 203.0 0.4 5.6e-55 186.2 0.2 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KXZ56967.1 - 2.8e-07 30.7 0.0 0.11 12.8 0.0 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KXZ56967.1 - 0.00049 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHAD PF05235.14 KXZ56967.1 - 0.013 15.5 0.3 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 CHAD domain IKI3 PF04762.12 KXZ56967.1 - 0.024 12.6 0.6 1.6 6.7 0.1 2.9 2 1 1 3 3 3 0 IKI3 family WD40 PF00400.32 KXZ56967.1 - 0.07 14.0 0.0 2.3e+02 2.9 0.0 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat Pkinase PF00069.25 KXZ56968.1 - 6.1e-49 166.7 0.0 8.7e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ56968.1 - 4.4e-25 88.4 0.0 6.4e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KXZ56968.1 - 9.3e-12 45.0 0.0 7.2e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KXZ56968.1 - 0.007 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PP2C PF00481.21 KXZ56969.1 - 3.7e-22 79.2 0.1 3.4e-10 40.0 0.0 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C TPR_1 PF00515.28 KXZ56970.1 - 4.3e-61 200.4 33.9 7.8e-10 38.2 0.1 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ56970.1 - 1.3e-47 156.1 34.6 4.6e-08 32.6 0.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 KXZ56970.1 - 7.7e-34 115.1 25.7 3.2e-06 26.7 0.1 8.6 4 2 4 8 8 8 7 TPR repeat TPR_8 PF13181.6 KXZ56970.1 - 2.4e-32 108.4 32.3 4.8e-05 23.2 0.1 9.8 10 0 0 10 10 9 7 Tetratricopeptide repeat STI1 PF17830.1 KXZ56970.1 - 1.6e-28 98.4 3.2 4.8e-14 52.0 0.3 2.5 2 0 0 2 2 2 2 STI1 domain TPR_12 PF13424.6 KXZ56970.1 - 3.6e-25 88.0 26.1 3.6e-07 30.4 0.6 7.7 5 3 1 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXZ56970.1 - 1e-22 80.5 28.4 7.7e-06 26.5 0.1 7.4 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXZ56970.1 - 1.5e-22 78.3 17.1 0.00033 21.2 0.0 8.9 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ56970.1 - 7.1e-17 60.1 13.9 0.00075 19.4 0.1 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXZ56970.1 - 2.2e-15 55.9 17.8 0.1 13.0 0.3 8.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXZ56970.1 - 3.7e-15 56.2 22.1 0.0023 18.4 0.0 7.2 4 3 4 8 8 7 6 Tetratricopeptide repeat TPR_9 PF13371.6 KXZ56970.1 - 1e-13 51.2 4.5 0.00062 19.9 0.3 6.0 3 3 3 6 6 6 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ56970.1 - 6.6e-10 38.9 11.5 0.086 12.9 0.1 6.3 6 0 0 6 6 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KXZ56970.1 - 1.5e-09 37.4 23.3 0.045 13.6 0.2 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ56970.1 - 3.6e-07 30.4 18.4 2.6 8.9 0.0 8.8 9 0 0 9 9 8 1 Tetratricopeptide repeat MIT PF04212.18 KXZ56970.1 - 0.0016 18.4 30.3 1.4 9.1 0.1 7.0 7 2 0 7 7 7 3 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 KXZ56970.1 - 0.0031 17.6 15.2 1.5 8.9 0.1 5.1 3 3 0 4 4 4 2 Domain of Unknown Function (DUF3856) BTAD PF03704.17 KXZ56970.1 - 0.0055 17.1 19.2 0.074 13.5 1.9 4.8 2 2 2 4 4 4 2 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KXZ56970.1 - 0.0065 16.7 18.0 0.61 10.3 2.0 5.5 3 3 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3584 PF12128.8 KXZ56970.1 - 0.037 11.5 8.3 0.071 10.6 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SHNi-TPR PF10516.9 KXZ56970.1 - 0.055 12.9 14.4 8.1 6.0 0.0 5.9 6 0 0 6 6 6 0 SHNi-TPR TPR_21 PF09976.9 KXZ56970.1 - 0.11 12.2 25.1 1.6 8.4 0.7 4.6 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 KXZ56970.1 - 0.13 12.3 0.0 0.13 12.3 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat AlkA_N PF06029.11 KXZ56970.1 - 0.13 12.5 0.5 2.9 8.2 0.0 2.9 3 0 0 3 3 2 0 AlkA N-terminal domain PI-PLC-X PF00388.19 KXZ56970.1 - 0.16 11.5 0.0 0.51 9.9 0.0 1.8 2 0 0 2 2 1 0 Phosphatidylinositol-specific phospholipase C, X domain TOM20_plant PF06552.12 KXZ56970.1 - 0.5 10.1 9.6 1.6 8.5 0.1 4.1 5 0 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_4 PF07721.14 KXZ56970.1 - 0.56 11.0 0.1 0.56 11.0 0.1 4.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXZ56970.1 - 2.6 8.4 9.6 2.8 8.3 0.1 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat Nbs1_C PF08599.10 KXZ56971.1 - 2.8 8.1 6.0 33 4.7 6.0 2.3 1 1 0 1 1 1 0 DNA damage repair protein Nbs1 Pro_isomerase PF00160.21 KXZ56972.1 - 2e-23 83.4 0.0 3.2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-Tim10_DDP PF02953.15 KXZ56973.1 - 3.5e-21 74.6 0.8 4.1e-21 74.4 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MIEAP PF16026.5 KXZ56973.1 - 0.0004 20.6 0.2 0.00048 20.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondria-eating protein Peptidase_C26 PF07722.13 KXZ56974.1 - 3.5e-15 56.4 0.0 1e-14 54.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KXZ56974.1 - 2.2e-07 30.9 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DEAD PF00270.29 KXZ56975.1 - 1.8e-19 70.2 0.0 3.2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KXZ56975.1 - 4.2e-17 62.7 0.0 4.2e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KXZ56975.1 - 1.2e-11 44.9 0.0 2.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ubiquitin PF00240.23 KXZ56975.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CDT1 PF08839.11 KXZ56975.1 - 0.14 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 DNA replication factor CDT1 like ResIII PF04851.15 KXZ56975.1 - 0.22 11.5 0.0 0.36 10.8 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FAST_1 PF06743.15 KXZ56977.1 - 6.1e-05 22.9 0.0 0.98 9.4 0.0 4.3 3 1 1 4 4 4 2 FAST kinase-like protein, subdomain 1 AAA_11 PF13086.6 KXZ56978.1 - 1.4e-53 182.4 0.0 2.5e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KXZ56978.1 - 3.1e-42 144.5 0.0 9.7e-21 74.3 0.0 3.3 2 1 1 3 3 3 3 AAA domain AAA_30 PF13604.6 KXZ56978.1 - 6.8e-09 35.7 3.8 0.0032 17.2 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXZ56978.1 - 1.2e-06 28.9 0.3 0.00065 20.1 0.3 3.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXZ56978.1 - 0.00012 21.9 0.0 0.027 14.2 0.0 2.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXZ56978.1 - 0.0017 18.0 0.3 0.033 13.7 0.0 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 KXZ56978.1 - 0.052 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1771 PF08590.10 KXZ56979.1 - 1.2 9.6 4.9 1 9.8 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) NTP_transferase PF00483.23 KXZ56980.1 - 5.2e-64 216.2 0.0 7.8e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase RNase_PH PF01138.21 KXZ56980.1 - 4.2e-13 49.9 0.0 1e-12 48.7 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NTP_transf_3 PF12804.7 KXZ56980.1 - 0.0018 18.7 0.4 0.0048 17.3 0.0 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain RNase_PH_C PF03725.15 KXZ56980.1 - 0.0022 18.0 0.7 0.0051 16.8 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Hexapep PF00132.24 KXZ56980.1 - 0.18 11.6 11.8 1.2 9.0 5.6 3.3 2 1 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXZ56980.1 - 6.2 6.7 14.9 2.1 8.1 0.4 4.6 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase LRR_6 PF13516.6 KXZ56981.1 - 2.3e-16 58.4 34.3 0.033 14.2 0.1 15.1 18 0 0 18 18 18 7 Leucine Rich repeat LRR_4 PF12799.7 KXZ56981.1 - 4.3e-10 39.7 8.2 1 9.9 0.0 8.2 7 3 2 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXZ56981.1 - 2e-08 33.8 14.3 0.042 13.6 1.3 7.3 7 1 0 7 7 7 4 Leucine rich repeat F-box-like PF12937.7 KXZ56981.1 - 0.00065 19.5 0.3 0.0031 17.4 0.3 2.2 1 0 0 1 1 1 1 F-box-like DUF525 PF04379.14 KXZ56982.1 - 1.1e-33 115.3 0.0 1.6e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 ApaG domain UVR PF02151.19 KXZ56982.1 - 0.00018 21.1 20.0 0.017 14.9 7.7 2.2 2 0 0 2 2 2 2 UvrB/uvrC motif DUF4145 PF13643.6 KXZ56982.1 - 0.072 13.2 0.6 0.15 12.2 0.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4145) Glyco_transf_34 PF05637.12 KXZ56983.1 - 2e-16 60.4 0.0 4.3e-08 33.2 0.0 2.0 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KXZ56983.1 - 0.048 13.2 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 KXZ56983.1 - 0.066 13.2 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Ribosomal_S3_C PF00189.20 KXZ56984.1 - 5.9e-24 84.4 0.5 2.1e-23 82.7 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KXZ56984.1 - 3.8e-12 45.8 0.1 7e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 KH domain Rib_5-P_isom_A PF06026.14 KXZ56985.1 - 7.4e-62 208.0 0.0 9.8e-62 207.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KXZ56985.1 - 0.0016 18.4 0.2 0.0074 16.2 0.2 2.1 1 1 0 1 1 1 1 DeoR C terminal sensor domain DUF2862 PF11061.8 KXZ56985.1 - 0.023 14.6 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) DUF4461 PF14688.6 KXZ56986.1 - 2.7e-08 34.0 0.5 5.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4461) Dynein_light PF01221.18 KXZ56987.1 - 2.7e-25 88.5 1.0 3.2e-25 88.2 1.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DHHA1 PF02272.19 KXZ56987.1 - 0.015 15.7 0.0 0.018 15.4 0.0 1.1 1 0 0 1 1 1 0 DHHA1 domain DHOase PF12890.7 KXZ56987.1 - 0.024 14.6 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 Dihydro-orotase-like Dynactin PF12455.8 KXZ56987.1 - 0.096 11.9 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Dynein associated protein HR_lesion PF05514.11 KXZ56988.1 - 0.082 13.1 0.1 0.094 12.9 0.1 1.1 1 0 0 1 1 1 0 HR-like lesion-inducing EF-hand_6 PF13405.6 KXZ56989.1 - 7.9e-17 59.7 1.2 0.0004 20.1 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 KXZ56989.1 - 4.3e-16 57.2 0.8 0.00014 21.1 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXZ56989.1 - 6.2e-15 55.4 2.5 4.7e-07 30.2 0.3 3.4 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KXZ56989.1 - 2.1e-09 36.5 0.3 0.072 12.6 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KXZ56989.1 - 5.6e-09 35.7 3.1 0.00072 19.4 0.1 4.2 3 1 1 4 4 4 3 EF-hand domain pair DUF842 PF05811.13 KXZ56991.1 - 0.018 14.8 3.1 0.073 12.8 0.3 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) LTXXQ PF07813.12 KXZ56991.1 - 0.028 15.2 1.3 1.4 9.7 0.0 3.0 2 2 1 3 3 3 0 LTXXQ motif family protein DivIC PF04977.15 KXZ56991.1 - 0.049 13.4 0.4 0.096 12.5 0.4 1.5 1 0 0 1 1 1 0 Septum formation initiator CNRIP1 PF15043.6 KXZ56992.1 - 4.1e-07 29.7 0.0 0.0037 16.8 0.0 2.2 2 0 0 2 2 2 2 CB1 cannabinoid receptor-interacting protein 1 Ank_4 PF13637.6 KXZ56993.1 - 1.8e-06 28.3 0.2 0.36 11.5 0.4 4.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ56993.1 - 5.2e-06 27.0 0.0 0.01 16.4 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Serglycin PF04360.12 KXZ56993.1 - 0.0017 18.3 0.6 0.0026 17.7 0.6 1.2 1 0 0 1 1 1 1 Serglycin Ank_3 PF13606.6 KXZ56993.1 - 0.0049 17.3 0.1 71 4.5 0.0 5.3 5 1 1 6 6 6 0 Ankyrin repeat Beta-lactamase PF00144.24 KXZ56994.1 - 7.7e-25 87.8 3.2 3.2e-24 85.8 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase SIS PF01380.22 KXZ56995.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 SIS domain RNA_pol_Rpc34 PF05158.12 KXZ56996.1 - 4.2e-77 259.8 0.2 3.6e-56 191.0 0.0 2.3 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit FrhB_FdhB_C PF04432.13 KXZ56996.1 - 0.03 14.2 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus zf-ZPR1 PF03367.13 KXZ56996.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain LT-IIB PF06453.11 KXZ56996.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) TPR_12 PF13424.6 KXZ56998.1 - 6.8e-05 23.1 0.2 6.8e-05 23.1 0.2 3.6 3 3 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXZ56998.1 - 0.0014 18.4 1.6 0.026 14.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXZ56998.1 - 0.0056 16.6 1.3 0.02 14.9 0.0 2.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXZ56998.1 - 0.1 12.8 9.6 0.75 10.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXZ56998.1 - 2.5 8.1 0.0 2.5 8.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXZ56998.1 - 2.7 8.4 6.7 5.1 7.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2065 PF09838.9 KXZ56999.1 - 0.033 14.2 0.7 0.075 13.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Arm PF00514.23 KXZ57002.1 - 0.0076 16.3 0.8 0.0076 16.3 0.8 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Mito_fiss_reg PF05308.11 KXZ57003.1 - 2.5 8.1 6.9 5.2 7.1 6.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CTP_transf_1 PF01148.20 KXZ57004.1 - 2.7e-66 224.1 10.4 3.3e-66 223.8 10.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family OPA3 PF07047.12 KXZ57005.1 - 5.1e-24 84.4 1.4 5.1e-24 84.4 1.4 1.8 2 1 0 2 2 2 1 Optic atrophy 3 protein (OPA3) HOOK PF05622.12 KXZ57005.1 - 0.0015 16.8 4.6 0.0017 16.6 4.6 1.0 1 0 0 1 1 1 1 HOOK protein DUF2076 PF09849.9 KXZ57005.1 - 0.023 14.8 2.9 0.087 12.9 3.6 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) PIN_8 PF18476.1 KXZ57005.1 - 0.11 12.3 2.5 0.15 11.9 2.5 1.2 1 0 0 1 1 1 0 PIN like domain zf-CpG_bind_C PF12269.8 KXZ57005.1 - 0.67 9.7 6.2 1 9.1 6.2 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain HXXSHH PF07586.11 KXZ57005.1 - 1 8.9 5.8 1.7 8.2 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) 2OG-FeII_Oxy_4 PF13661.6 KXZ57006.1 - 2e-13 50.8 0.0 7.7e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXZ57006.1 - 2.2e-10 41.3 0.0 3.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 KXZ57007.1 - 7.8e-46 156.0 0.0 1.3e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXZ57007.1 - 3.6e-24 85.2 0.0 1.5e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXZ57007.1 - 1.1e-19 70.4 0.2 1.9e-19 69.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXZ57007.1 - 0.00031 20.8 0.0 0.0006 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 KXZ57007.1 - 0.017 14.6 22.9 0.034 13.6 22.9 1.4 1 0 0 1 1 1 0 SDA1 Telomere_reg-2 PF10193.9 KXZ57008.1 - 1.4e-05 25.5 0.0 8.9e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein PP2C PF00481.21 KXZ57009.1 - 1.6e-29 103.3 0.8 1e-18 68.0 0.3 4.8 3 1 0 3 3 3 2 Protein phosphatase 2C TMF_TATA_bd PF12325.8 KXZ57009.1 - 1.3e-20 73.7 10.3 1.3e-20 73.7 10.3 6.3 3 2 5 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXZ57009.1 - 1.2e-09 38.0 11.9 1.2e-09 38.0 11.9 8.2 7 2 0 8 8 8 2 TATA element modulatory factor 1 DNA binding LIP PF03583.14 KXZ57009.1 - 0.027 13.8 0.8 0.052 12.9 0.8 1.4 1 0 0 1 1 1 0 Secretory lipase Spc7 PF08317.11 KXZ57009.1 - 0.2 10.5 70.4 0.15 10.9 4.8 5.5 2 2 2 5 5 5 0 Spc7 kinetochore protein DUF5082 PF16888.5 KXZ57009.1 - 0.8 10.0 29.3 1.3 9.3 1.5 6.0 3 2 2 5 5 5 0 Domain of unknown function (DUF5082) Scaffolding_pro PF11418.8 KXZ57009.1 - 5.3 7.7 6.8 0.69 10.5 1.2 2.4 3 0 0 3 3 3 0 Phi29 scaffolding protein Cmyb_C PF09316.10 KXZ57009.1 - 7 6.3 6.8 1.7 8.3 1.5 2.5 3 0 0 3 3 3 0 C-myb, C-terminal GAS PF13851.6 KXZ57009.1 - 9.3 5.5 62.7 0.22 10.9 8.6 5.2 2 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.16 KXZ57010.1 - 5e-51 173.7 38.5 5e-51 173.7 38.5 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXZ57010.1 - 2.6e-10 40.1 34.5 2.1e-07 30.6 11.2 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KXZ57010.1 - 9.3e-10 37.9 5.5 9.3e-10 37.9 5.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1180 PF06679.12 KXZ57010.1 - 0.9 9.9 9.5 0.048 14.1 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) BACK PF07707.15 KXZ57011.1 - 0.00023 21.2 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch FabA PF07977.13 KXZ57012.1 - 5.1e-33 113.6 0.0 6.2e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain 4HBT PF03061.22 KXZ57012.1 - 0.0016 18.8 0.1 0.014 15.8 0.0 2.2 1 1 1 2 2 2 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 KXZ57012.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain 60KD_IMP PF02096.20 KXZ57013.1 - 0.0042 17.0 0.1 2.1 8.3 0.0 2.2 2 0 0 2 2 2 2 60Kd inner membrane protein TPR_2 PF07719.17 KXZ57013.1 - 0.033 14.3 0.2 0.11 12.6 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXZ57013.1 - 0.045 14.4 0.1 0.18 12.5 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXZ57013.1 - 0.058 13.5 0.3 0.16 12.1 0.3 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF4988 PF16378.5 KXZ57014.1 - 0.071 12.8 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function START PF01852.19 KXZ57015.1 - 5.3e-09 35.8 0.0 8.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 START domain DUF4242 PF14026.6 KXZ57015.1 - 0.16 12.2 0.6 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) PP2C PF00481.21 KXZ57016.1 - 1.3e-18 67.6 0.0 1.5e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXZ57016.1 - 0.016 15.1 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Peptidase_C78 PF07910.13 KXZ57017.1 - 2.1e-45 154.8 0.0 3.1e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KXZ57017.1 - 0.077 12.4 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase family C54 DUF3067 PF11267.8 KXZ57019.1 - 4.6e-12 46.4 0.0 8.1e-09 36.0 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3067) DIL PF01843.19 KXZ57020.1 - 1.8e-16 60.3 0.0 7.9e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 DIL domain DUF3292 PF11696.8 KXZ57020.1 - 4.4 5.6 5.8 9.8 4.4 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) GSHPx PF00255.19 KXZ57021.1 - 2.6e-43 146.0 0.1 3.4e-43 145.6 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXZ57021.1 - 1.9e-06 27.8 0.0 7.6e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXZ57021.1 - 0.00059 19.6 0.1 0.0019 17.9 0.1 1.8 1 1 0 1 1 1 1 Redoxin PAP_fibrillin PF04755.12 KXZ57022.1 - 8.4e-19 68.3 0.1 2.4e-18 66.8 0.1 1.7 1 1 0 1 1 1 1 PAP_fibrillin Ndc1_Nup PF09531.10 KXZ57024.1 - 7.2e-13 48.1 0.0 5.1e-06 25.5 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin protein Ndc1-Nup Pmp3 PF01679.17 KXZ57025.1 - 2.1e-17 63.0 8.0 2.5e-17 62.8 8.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF872 PF05915.12 KXZ57025.1 - 0.034 14.3 2.8 0.037 14.2 2.8 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Sugar_tr PF00083.24 KXZ57026.1 - 5.1e-100 335.5 12.2 6.4e-100 335.1 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXZ57026.1 - 2.1e-19 69.7 42.2 3.8e-18 65.5 35.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin_N PF00134.23 KXZ57028.1 - 4.2e-47 159.0 2.4 1.3e-46 157.5 0.3 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXZ57028.1 - 1.1e-32 112.6 2.3 2.7e-32 111.3 0.3 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Ribosomal_L4 PF00573.22 KXZ57029.1 - 1.5e-40 138.9 0.2 2.5e-40 138.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KXZ57029.1 - 1.7e-27 95.2 2.8 4.9e-27 93.8 0.7 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain RRN3 PF05327.11 KXZ57030.1 - 1.1e-100 337.8 0.0 2.4e-99 333.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 BTAD PF03704.17 KXZ57030.1 - 4.2 7.8 6.3 25 5.3 0.3 4.3 5 1 1 6 6 6 0 Bacterial transcriptional activator domain SpoIIIAH PF12685.7 KXZ57030.1 - 4.2 7.1 6.0 33 4.2 2.7 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF2760 PF10816.8 KXZ57032.1 - 0.13 12.1 0.1 8.9 6.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2760) Guanylate_cyc PF00211.20 KXZ57034.1 - 3.5e-15 56.1 0.0 4.2e-06 26.5 0.0 3.7 3 1 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain Ribosomal_L1 PF00687.21 KXZ57035.1 - 1.3e-57 194.9 0.3 1.6e-57 194.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Rib_5-P_isom_A PF06026.14 KXZ57035.1 - 8.6e-06 25.5 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Methyltransf_4 PF02390.17 KXZ57036.1 - 1.1e-50 171.4 0.0 1.5e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KXZ57036.1 - 9.9e-06 26.2 0.0 0.0018 19.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ57036.1 - 8.5e-05 23.1 0.0 0.56 10.9 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 KXZ57036.1 - 0.029 13.7 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KXZ57036.1 - 0.089 13.5 0.0 0.77 10.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 KXZ57036.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 KXZ57036.1 - 0.11 12.1 0.0 0.47 10.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain tRNA_edit PF04073.15 KXZ57037.1 - 9.9e-19 67.6 0.3 9.1e-18 64.5 0.1 2.4 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain DUF3682 PF12446.8 KXZ57037.1 - 5.2 7.6 12.7 8.6 6.9 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) HSP70 PF00012.20 KXZ57040.1 - 9.8e-263 872.8 11.3 1.1e-262 872.6 11.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXZ57040.1 - 5.3e-18 64.9 4.1 2e-16 59.7 0.1 2.7 2 1 1 3 3 3 2 MreB/Mbl protein StbA PF06406.11 KXZ57040.1 - 0.00056 19.2 0.1 0.037 13.3 0.0 2.5 1 1 0 2 2 2 1 StbA protein FtsA PF14450.6 KXZ57040.1 - 0.0038 17.6 4.4 0.1 13.0 0.0 3.7 4 1 0 4 4 4 1 Cell division protein FtsA DP PF08781.10 KXZ57040.1 - 0.1 12.5 3.8 0.76 9.7 0.0 2.5 2 0 0 2 2 2 0 Transcription factor DP DUF3138 PF11336.8 KXZ57040.1 - 0.3 9.7 4.9 0.11 11.1 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF3347 PF11827.8 KXZ57040.1 - 1.2 9.3 7.7 3.1 8.0 7.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) V-ATPase_C PF03223.15 KXZ57041.1 - 4.8e-112 375.0 0.3 5.5e-112 374.8 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C GlnE PF03710.15 KXZ57041.1 - 0.064 12.7 0.4 0.13 11.7 0.3 1.5 1 1 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase ERM PF00769.19 KXZ57041.1 - 0.064 13.1 3.4 0.19 11.5 3.4 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Hc1 PF07432.13 KXZ57041.1 - 0.11 12.9 0.3 0.26 11.6 0.1 1.7 2 0 0 2 2 2 0 Histone H1-like protein Hc1 CENP-F_leu_zip PF10473.9 KXZ57041.1 - 0.11 12.5 2.2 1.9 8.5 0.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 KXZ57041.1 - 0.14 12.2 1.8 1.8 8.6 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit HSCB_C PF07743.13 KXZ57041.1 - 0.18 12.3 2.8 0.64 10.5 0.0 3.0 4 0 0 4 4 4 0 HSCB C-terminal oligomerisation domain ADIP PF11559.8 KXZ57041.1 - 0.64 10.1 3.6 0.82 9.8 0.5 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FliD_N PF02465.18 KXZ57041.1 - 2.3 9.0 6.2 2.4 8.9 0.3 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Malic_M PF03949.15 KXZ57043.1 - 2.2e-62 210.7 0.0 2.8e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXZ57043.1 - 4.7e-62 209.0 0.0 6.6e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain HetR_C PF18460.1 KXZ57043.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Q_salvage PF10343.9 KXZ57043.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Aconitase_C PF00694.19 KXZ57044.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.7 2 0 0 2 2 2 0 Aconitase C-terminal domain S-AdoMet_synt_C PF02773.16 KXZ57046.1 - 5.3e-62 207.9 0.0 9.4e-62 207.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KXZ57046.1 - 1.5e-47 160.8 0.0 3.2e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KXZ57046.1 - 1.8e-43 147.2 0.6 4.1e-43 146.1 0.6 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Spermine_synth PF01564.17 KXZ57047.1 - 2.4e-26 92.3 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 KXZ57047.1 - 2.6e-06 28.0 0.0 5.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXZ57047.1 - 0.00016 22.2 0.0 0.00042 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXZ57047.1 - 0.025 13.9 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KXZ57047.1 - 0.039 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain NT5C PF06941.12 KXZ57047.1 - 0.042 13.7 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Methyltransf_12 PF08242.12 KXZ57047.1 - 0.042 14.6 0.0 0.076 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KXZ57047.1 - 0.057 13.3 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DUF43 PF01861.16 KXZ57047.1 - 0.063 12.5 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain eIF-5_eIF-2B PF01873.17 KXZ57048.1 - 6.4e-39 132.5 0.9 1.4e-38 131.3 0.9 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KXZ57048.1 - 2.4e-15 56.4 0.7 2.4e-15 56.4 0.7 2.9 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon TFIIF_alpha PF05793.12 KXZ57048.1 - 0.00079 18.1 34.4 0.00079 18.1 34.4 1.8 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LAP1C PF05609.12 KXZ57048.1 - 0.48 9.5 16.6 0.69 8.9 16.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SURF2 PF05477.11 KXZ57048.1 - 3.4 7.3 25.6 7.7 6.1 25.6 1.6 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Med19 PF10278.9 KXZ57048.1 - 3.8 7.4 30.4 0.16 11.9 20.5 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Ndc1_Nup PF09531.10 KXZ57048.1 - 8.9 4.9 5.6 12 4.5 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RT_RNaseH PF17917.1 KXZ57050.1 - 3.3e-30 104.5 0.0 6.8e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KXZ57050.1 - 8.7e-26 89.9 0.0 1.8e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KXZ57050.1 - 7.4e-16 58.4 0.0 1.8e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KXZ57050.1 - 1.1e-14 54.5 0.0 2.3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KXZ57050.1 - 2.9e-14 52.9 0.1 6.2e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KXZ57050.1 - 0.032 14.4 0.1 0.085 13.1 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger GRP PF07172.11 KXZ57050.1 - 0.17 12.6 11.1 0.51 11.1 11.1 1.7 1 0 0 1 1 1 0 Glycine rich protein family SpoIIE PF07228.12 KXZ57051.1 - 2e-13 50.7 0.1 2.8e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXZ57051.1 - 3.5e-10 39.9 0.3 0.00078 19.1 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXZ57051.1 - 1.2e-07 31.6 1.3 1.8e-07 31.0 1.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Dimer_Tnp_hAT PF05699.14 KXZ57052.1 - 0.00027 20.7 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2397 PF09660.10 KXZ57052.1 - 0.35 9.7 7.6 0.62 8.9 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) DUF4371 PF14291.6 KXZ57053.1 - 4.2e-09 36.4 0.5 4.2e-09 36.4 0.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KXZ57053.1 - 0.00028 20.8 0.1 0.00053 19.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cullin_binding PF03556.15 KXZ57053.1 - 0.054 13.9 0.5 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Cullin binding Retrotrans_gag PF03732.17 KXZ57053.1 - 0.069 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Dimer_Tnp_hAT PF05699.14 KXZ57054.1 - 0.00027 20.7 0.0 0.00065 19.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Phage_integrase PF00589.22 KXZ57055.1 - 0.0014 18.5 0.4 0.0029 17.4 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family RVT_1 PF00078.27 KXZ57056.1 - 9.6e-10 38.3 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 KXZ57056.1 - 4.5e-06 26.3 0.1 8.3e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RVT_3 PF13456.6 KXZ57056.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like RNase_H PF00075.24 KXZ57056.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 RNase H DUF4371 PF14291.6 KXZ57058.1 - 2.9e-09 36.9 1.9 3e-09 36.9 0.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 KXZ57058.1 - 0.00019 21.4 0.1 0.00034 20.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Retrotrans_gag PF03732.17 KXZ57058.1 - 0.063 13.6 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Cullin_binding PF03556.15 KXZ57058.1 - 0.1 13.1 0.6 0.73 10.3 0.0 2.1 2 0 0 2 2 2 0 Cullin binding WD40 PF00400.32 KXZ57059.1 - 1.5e-30 104.7 10.8 2.9e-05 24.7 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXZ57059.1 - 3.2e-06 27.4 0.0 0.55 10.6 0.0 3.8 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1_Xtn PF16897.5 KXZ57060.1 - 7e-38 128.9 0.2 1.6e-37 127.7 0.1 1.6 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KXZ57060.1 - 7.9e-26 89.9 0.1 1.3e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KXZ57060.1 - 6.3e-19 68.2 0.0 1.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXZ57060.1 - 6.3e-09 35.6 0.1 2.7e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KXZ57060.1 - 0.0052 15.8 0.5 0.018 14.1 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KXZ57060.1 - 0.0053 16.8 0.1 1.7 8.7 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KXZ57060.1 - 0.045 13.3 0.7 7.2 6.1 0.0 3.6 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain zf-FPG_IleRS PF06827.14 KXZ57060.1 - 0.066 13.1 0.2 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Na_sulph_symp PF00939.19 KXZ57061.1 - 2.4e-26 92.8 32.5 3.4e-26 92.3 32.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXZ57061.1 - 5e-25 88.3 62.3 8.6e-23 81.0 32.4 2.1 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 KXZ57061.1 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 SPX domain RVT_1 PF00078.27 KXZ57062.1 - 9.8e-13 48.1 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4035 PF13227.6 KXZ57062.1 - 0.25 11.1 1.6 0.42 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) RVT_1 PF00078.27 KXZ57070.1 - 6.4e-24 84.7 0.0 8.3e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 KXZ57073.1 - 0.027 15.1 0.0 0.11 13.1 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease CCDC53 PF10152.9 KXZ57073.1 - 0.2 12.1 21.6 0.79 10.1 3.1 4.2 4 0 0 4 4 4 0 Subunit CCDC53 of WASH complex GTP_EFTU PF00009.27 KXZ57075.1 - 5.1e-29 101.2 0.0 8.8e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXZ57075.1 - 1.4e-07 31.5 0.0 2.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXZ57075.1 - 0.00012 21.6 0.2 0.00043 19.8 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 KXZ57075.1 - 0.00026 21.3 0.1 0.0013 19.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 cobW PF02492.19 KXZ57075.1 - 0.0027 17.3 0.4 0.036 13.7 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KXZ57075.1 - 0.003 17.5 0.2 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KXZ57075.1 - 0.13 12.0 0.4 22 4.7 0.1 2.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.21 KXZ57075.1 - 0.15 11.5 0.0 0.43 10.0 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Peptidase_M48 PF01435.18 KXZ57076.1 - 2.5e-05 24.1 0.5 0.034 13.9 0.1 2.1 2 0 0 2 2 2 2 Peptidase family M48 Peptidase_M78 PF06114.13 KXZ57076.1 - 0.042 13.8 2.3 3.6 7.5 0.1 2.5 2 1 1 3 3 3 0 IrrE N-terminal-like domain Ribosomal_L37ae PF01780.19 KXZ57078.1 - 6.2e-40 135.2 8.5 6.9e-40 135.0 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.10 KXZ57078.1 - 0.033 13.9 2.0 0.18 11.5 0.2 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain NOB1_Zn_bind PF08772.11 KXZ57078.1 - 0.046 13.9 3.3 0.24 11.6 3.2 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Prok-RING_2 PF14445.6 KXZ57078.1 - 0.059 13.5 0.7 0.1 12.8 0.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Rpr2 PF04032.16 KXZ57078.1 - 0.17 12.2 1.9 1.4 9.3 0.1 2.2 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain MRNIP PF15749.5 KXZ57078.1 - 0.77 10.5 4.4 5.5 7.7 1.8 2.1 1 1 1 2 2 2 0 MRN-interacting protein Pkinase PF00069.25 KXZ57079.1 - 8.2e-70 235.2 0.0 1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXZ57079.1 - 3.5e-42 144.5 0.0 4.5e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.7 KXZ57079.1 - 5e-07 29.9 0.0 1.6e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 PAS domain Kinase-like PF14531.6 KXZ57079.1 - 8.4e-06 25.3 0.0 3.2e-05 23.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KXZ57079.1 - 0.00076 19.5 0.4 0.0029 17.6 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXZ57079.1 - 0.002 17.5 0.1 0.0031 16.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXZ57079.1 - 0.0021 17.0 0.0 0.0031 16.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain PAS_4 PF08448.10 KXZ57079.1 - 0.0025 18.0 0.0 0.0062 16.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KXZ57079.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 KXZ57079.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_3 PF08447.12 KXZ57079.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold ATP-synt_C PF00137.21 KXZ57080.1 - 4.9e-35 119.7 39.8 8.1e-21 74.1 15.7 2.3 2 0 0 2 2 2 2 ATP synthase subunit C 14-3-3 PF00244.20 KXZ57081.1 - 4.5e-94 314.1 8.4 5.1e-94 313.9 8.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3560 PF12083.8 KXZ57081.1 - 0.016 15.3 1.8 0.95 9.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3560) WND PF07861.11 KXZ57081.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 WisP family N-Terminal Region UPF0160 PF03690.13 KXZ57081.1 - 0.06 13.0 0.4 0.098 12.3 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) SpoIIE PF07228.12 KXZ57082.1 - 0.00069 19.6 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Adeno_PIX PF03955.14 KXZ57082.1 - 0.089 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) KRTAP PF11759.8 KXZ57085.1 - 0.00066 20.2 73.4 1.8e+04 -27.2 73.4 3.5 1 1 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 KXZ57085.1 - 3.4 7.8 84.6 1.8e+04 -29.3 84.6 3.1 1 1 0 1 1 1 0 Keratin type II head Ank_4 PF13637.6 KXZ57086.1 - 1.9e-15 57.0 0.9 5.4e-08 33.2 0.0 4.8 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXZ57086.1 - 3.9e-14 53.0 0.2 2e-10 41.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXZ57086.1 - 5.1e-12 44.9 0.0 0.0004 20.6 0.0 5.3 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXZ57086.1 - 3e-11 43.3 0.5 6.7e-06 26.3 0.0 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXZ57086.1 - 1.3e-09 38.1 4.2 2.7e-05 24.4 0.1 4.7 6 0 0 6 6 6 2 Ankyrin repeat RB_A PF01858.17 KXZ57087.1 - 3.4e-43 147.8 0.1 1.3e-42 145.9 0.0 2.1 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KXZ57087.1 - 1.6e-37 128.5 1.2 4.5e-37 127.0 1.2 1.8 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KXZ57087.1 - 9.2e-08 31.7 0.2 5.4e-07 29.3 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3452) RWP-RK PF02042.15 KXZ57088.1 - 1.1e-22 79.7 0.0 1.8e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_17 PF12728.7 KXZ57088.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 KXZ57088.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_Tnp_ISL3 PF13542.6 KXZ57088.1 - 0.19 11.2 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Arm PF00514.23 KXZ57089.1 - 5.8e-11 42.0 15.3 1.1e-05 25.3 0.2 8.8 7 1 0 8 8 8 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 KXZ57089.1 - 0.0045 17.0 0.1 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) WAPL PF07814.13 KXZ57089.1 - 0.015 14.1 0.3 0.067 12.0 0.0 2.1 3 0 0 3 3 3 0 Wings apart-like protein regulation of heterochromatin HEAT_EZ PF13513.6 KXZ57089.1 - 5.8 7.5 12.8 19 5.9 0.6 5.1 5 0 0 5 5 5 0 HEAT-like repeat # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Gonium_pectorale-ASM158458v1/GCA_001584585.1_ASM158458v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Gonium_pectorale-ASM158458v1/GCA_001584585.1_ASM158458v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Gonium_pectorale-ASM158458v1/GCA_001584585.1_ASM158458v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Gonium_pectorale-ASM158458v1/GCA_001584585.1_ASM158458v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 06:33:30 2019 # [ok]