# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Bac_DnaA PF00308.18 AAG03391.1 - 7.1e-100 333.3 0.4 1e-99 332.8 0.4 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 AAG03391.1 - 4.6e-32 109.9 0.1 1.2e-31 108.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 AAG03391.1 - 2.6e-21 75.1 0.1 6.6e-21 73.8 0.1 1.8 1 0 0 1 1 1 1 DnaA N-terminal domain IstB_IS21 PF01695.17 AAG03391.1 - 1.6e-08 34.5 0.0 2.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 AAG03391.1 - 3.9e-06 27.3 0.0 1.5e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Kinesin PF00225.23 AAG03391.1 - 0.00015 20.9 0.0 0.00062 18.8 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain AFG1_ATPase PF03969.16 AAG03391.1 - 0.00019 20.4 0.3 0.00057 18.9 0.3 1.8 1 1 0 1 1 1 1 AFG1-like ATPase AAA_14 PF13173.6 AAG03391.1 - 0.0016 18.5 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AAG03391.1 - 0.0028 17.6 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AAG03391.1 - 0.0056 16.9 1.8 0.25 11.6 0.3 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAG03391.1 - 0.037 14.4 0.3 0.15 12.4 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 AAG03391.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.15 AAG03391.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 AAG03391.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 AAG03391.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 AAG03391.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain FAP PF07174.11 AAG03391.1 - 4.9 6.5 19.9 8.1 5.8 19.1 1.7 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) DNA_pol3_beta_2 PF02767.16 AAG03392.1 - 3.7e-48 162.6 0.1 1.8e-39 134.6 0.0 2.7 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 AAG03392.1 - 1.4e-47 160.8 0.1 8.9e-42 142.0 0.0 2.9 3 0 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 AAG03392.1 - 7.9e-44 148.4 0.2 4.6e-41 139.5 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III beta subunit, C-terminal domain HSP20 PF00011.21 AAG03392.1 - 0.0033 17.5 0.3 0.049 13.8 0.0 2.6 3 0 0 3 3 3 1 Hsp20/alpha crystallin family TubC_N PF18563.1 AAG03392.1 - 0.0065 16.4 1.3 1.4 8.9 0.0 4.3 5 0 0 5 5 5 1 TubC N-terminal docking domain SMC_N PF02463.19 AAG03393.1 - 6.8e-33 114.0 0.0 8.2e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG03393.1 - 1.2e-07 32.5 0.0 1.8e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAG03393.1 - 2.3e-06 27.7 0.2 3.4e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAG03393.1 - 0.00018 21.3 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 AAG03393.1 - 0.00051 20.5 3.9 0.079 13.3 3.9 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 AAG03393.1 - 0.00056 18.7 0.0 0.0008 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG03393.1 - 0.00095 18.9 0.0 0.0053 16.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAG03393.1 - 0.016 15.7 0.1 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_27 PF13514.6 AAG03393.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG03393.1 - 0.088 13.1 0.1 0.4 10.9 0.0 2.2 1 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAG03393.1 - 0.2 11.5 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DNA_gyraseB PF00204.25 AAG03394.1 - 3.7e-57 192.6 0.6 6.9e-57 191.7 0.6 1.5 1 0 0 1 1 1 1 DNA gyrase B GyrB_insert PF18053.1 AAG03394.1 - 1.7e-52 177.7 0.0 3.3e-52 176.7 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain DNA_gyraseB_C PF00986.21 AAG03394.1 - 5.4e-31 106.6 0.1 1.2e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AAG03394.1 - 1.2e-22 80.5 0.2 3.1e-22 79.2 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AAG03394.1 - 6.6e-18 64.8 0.0 1.9e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 AAG03394.1 - 7.5e-05 22.6 0.1 0.00017 21.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acyltransferase PF01553.21 AAG03395.1 - 7.5e-23 80.6 0.0 1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Hydrolase_like PF13242.6 AAG03396.1 - 2.6e-12 46.6 0.0 4.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PNK3P PF08645.11 AAG03396.1 - 3.3e-08 33.4 0.0 4.2e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.26 AAG03396.1 - 6.5e-07 29.9 0.0 1.4e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAG03396.1 - 1.3e-06 28.6 0.0 0.00037 20.6 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG03396.1 - 4.2e-05 24.0 0.1 8.3e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAG03396.1 - 0.0018 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase MitoNEET_N PF10660.9 AAG03396.1 - 0.025 14.6 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Cytochrome_CBB3 PF13442.6 AAG03397.1 - 0.0017 18.6 0.0 11 6.4 0.0 3.6 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG03397.1 - 0.02 16.0 0.0 34 5.7 0.0 3.5 3 0 0 3 3 3 0 Cytochrome c tRNA_synt_2f PF02092.17 AAG03398.1 - 1.5e-205 684.2 0.0 1.9e-205 683.9 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 AAG03398.1 - 4.8e-07 30.0 0.5 1.3e-06 28.6 0.5 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_2e PF02091.15 AAG03399.1 - 1.6e-152 506.6 0.0 1.8e-152 506.4 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit Adenine_glyco PF03352.13 AAG03400.1 - 1.3e-70 236.8 0.0 1.6e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Lip_A_acyltrans PF03279.13 AAG03401.1 - 1.3e-44 152.6 0.0 1.5e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase PilZ PF07238.14 AAG03402.1 - 1.6e-09 38.0 0.0 1.7e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 PilZ domain Vut_1 PF02592.15 AAG03403.1 - 2.9e-35 121.8 9.2 2.9e-35 121.8 9.2 2.0 2 0 0 2 2 2 1 Putative vitamin uptake transporter DUF373 PF04123.13 AAG03403.1 - 0.56 9.6 3.5 0.77 9.1 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) TPR_19 PF14559.6 AAG03405.1 - 1.1e-09 38.7 7.0 1.2e-05 25.7 2.8 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAG03405.1 - 2e-08 34.4 5.1 1.1e-05 25.8 0.2 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAG03405.1 - 2.9e-08 33.2 4.3 0.00021 21.1 0.3 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAG03405.1 - 1.7e-06 28.6 5.4 2.4e-06 28.1 5.4 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAG03405.1 - 1e-05 25.5 0.3 0.00072 19.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAG03405.1 - 2.8e-05 23.7 1.7 0.0075 16.0 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAG03405.1 - 5e-05 23.7 3.0 0.011 16.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 AAG03405.1 - 0.00063 20.0 0.1 0.0012 19.1 0.1 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAG03405.1 - 0.001 19.3 2.2 0.24 11.7 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAG03405.1 - 0.0068 16.1 2.1 0.031 14.0 0.2 2.5 1 1 2 3 3 3 1 TPR repeat TPR_4 PF07721.14 AAG03405.1 - 0.0074 16.8 14.5 0.13 12.9 2.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAG03405.1 - 0.0077 16.4 0.1 0.046 13.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAG03405.1 - 0.093 12.8 0.8 0.91 9.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 AAG03405.1 - 0.17 12.1 4.4 0.34 11.1 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAG03405.1 - 0.59 10.1 3.3 8.5 6.4 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TrkA_N PF02254.18 AAG03406.1 - 6.5e-52 174.7 4.0 1.5e-26 93.0 0.1 2.9 3 0 0 3 3 2 2 TrkA-N domain TrkA_C PF02080.21 AAG03406.1 - 1.1e-27 95.7 1.0 1.7e-12 47.0 0.2 3.0 2 0 0 2 2 2 2 TrkA-C domain NAD_binding_7 PF13241.6 AAG03406.1 - 5.1e-11 42.9 0.2 0.00065 20.1 0.1 3.3 2 1 1 3 3 3 2 Putative NAD(P)-binding F420_oxidored PF03807.17 AAG03406.1 - 5e-08 33.4 0.2 0.0053 17.3 0.0 2.9 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAG03406.1 - 2.9e-07 30.8 0.1 0.0026 18.0 0.0 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AAG03406.1 - 4.3e-07 30.1 0.0 0.0064 16.6 0.0 2.7 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AAG03406.1 - 7.8e-07 28.8 0.2 0.00043 20.0 0.1 2.6 2 1 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 AAG03406.1 - 3.8e-05 24.1 0.1 0.42 11.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG03406.1 - 0.00012 21.7 0.0 0.00034 20.2 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 AAG03406.1 - 0.00026 21.2 0.1 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AAG03406.1 - 0.00039 20.4 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 AAG03406.1 - 0.00047 19.5 0.1 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AA_kinase PF00696.28 AAG03406.1 - 0.0011 18.6 0.4 0.0062 16.2 0.2 2.4 2 1 0 2 2 2 1 Amino acid kinase family 3HCDH_N PF02737.18 AAG03406.1 - 0.0012 18.7 0.1 0.043 13.7 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 AAG03406.1 - 0.0049 17.4 0.4 0.33 11.4 0.1 2.7 3 0 0 3 3 2 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 AAG03406.1 - 0.01 15.2 0.4 1 8.6 0.2 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ComX PF05952.12 AAG03406.1 - 0.046 13.7 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Bacillus competence pheromone ComX DUF1188 PF06690.11 AAG03406.1 - 0.074 12.6 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Thi4 PF01946.17 AAG03406.1 - 0.12 11.6 1.4 4.4 6.5 0.0 2.5 3 0 0 3 3 3 0 Thi4 family YflT PF11181.8 AAG03406.1 - 0.16 12.5 0.1 35 5.0 0.0 2.6 1 1 1 2 2 2 0 Heat induced stress protein YflT ThiF PF00899.21 AAG03406.1 - 0.2 11.0 0.6 0.77 9.1 0.5 1.9 2 0 0 2 2 2 0 ThiF family Methyltr_RsmB-F PF01189.17 AAG03407.1 - 5.2e-63 212.3 0.0 7.6e-63 211.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 AAG03407.1 - 1.2e-21 77.3 0.0 2.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 NusB family Methyltransf_25 PF13649.6 AAG03407.1 - 2.6e-06 28.0 0.1 1.5e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAG03407.1 - 6e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAG03407.1 - 6.1e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAG03407.1 - 0.00036 20.7 0.0 0.00052 20.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmF_N PF17125.5 AAG03407.1 - 0.0015 19.0 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_11 PF08241.12 AAG03407.1 - 0.046 14.4 0.1 0.42 11.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 AAG03407.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 AAG03407.1 - 0.054 12.8 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 AAG03407.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 AAG03407.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Formyl_trans_N PF00551.19 AAG03408.1 - 5.8e-47 159.8 0.0 7.3e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AAG03408.1 - 3e-26 91.6 0.0 5.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Pep_deformylase PF01327.21 AAG03409.1 - 5.5e-53 178.8 0.0 6.4e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase LysM PF01476.20 AAG03410.1 - 2.2e-13 50.0 0.0 6e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 LysM domain DNA_processg_A PF02481.15 AAG03411.1 - 1.5e-75 253.1 0.0 1.8e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 AAG03411.1 - 5.2e-10 39.3 6.2 1.7e-09 37.6 6.2 2.0 1 0 0 1 1 1 1 DprA winged helix domain LDcluster4 PF18306.1 AAG03411.1 - 0.017 14.7 1.1 0.044 13.4 1.0 1.7 2 0 0 2 2 2 0 SLOG cluster4 family Sua5_yciO_yrdC PF01300.18 AAG03412.1 - 4.6e-43 146.8 0.0 5.1e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination ADH_zinc_N PF00107.26 AAG03413.1 - 6.4e-24 84.4 0.0 9.8e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAG03413.1 - 3.4e-18 67.0 0.0 5.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG03413.1 - 4e-09 36.3 0.0 9.4e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Coprogen_oxidas PF01218.18 AAG03414.1 - 1.1e-132 441.2 0.0 1.3e-132 441.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Shikimate_dh_N PF08501.11 AAG03415.1 - 2.4e-24 85.4 0.0 5.5e-24 84.2 0.0 1.6 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AAG03415.1 - 4.7e-11 42.3 0.4 9.7e-11 41.3 0.4 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AAG03415.1 - 2.8e-07 30.7 0.0 4.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rotamase_2 PF13145.6 AAG03417.1 - 1.2e-07 32.5 1.0 2.4e-07 31.6 0.1 2.0 2 1 1 3 3 3 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAG03417.1 - 1.8e-05 25.6 0.0 0.00053 20.9 0.0 2.7 2 1 1 3 3 3 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AAG03417.1 - 0.00094 19.7 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF2087 PF09860.9 AAG03417.1 - 0.037 14.2 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) She9_MDM33 PF05546.11 AAG03418.1 - 0.12 12.2 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family Sulfate_transp PF00916.20 AAG03419.1 - 1.3e-71 241.4 10.6 1.8e-71 240.9 10.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 AAG03419.1 - 2.7e-08 34.0 2.6 1.6e-07 31.5 2.6 2.4 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAG03419.1 - 1.3e-07 31.2 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain tRNA_bind_3 PF17176.4 AAG03419.1 - 0.17 12.2 1.8 3.4 8.0 0.2 2.6 2 0 0 2 2 2 0 tRNA-binding domain DUF2583 PF10762.9 AAG03419.1 - 0.27 11.7 1.5 1.1 9.7 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) OpuAC PF04069.12 AAG03420.1 - 9.9e-56 189.2 0.0 1.1e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Sulfatase PF00884.23 AAG03421.1 - 3e-52 177.9 0.0 4e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 AAG03421.1 - 6.5e-25 86.7 4.2 1.8e-24 85.3 4.2 1.8 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 AAG03421.1 - 2.6e-06 27.3 0.0 0.008 15.8 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 AAG03421.1 - 0.00029 21.1 0.0 0.00057 20.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 AAG03421.1 - 0.0015 19.3 0.2 0.01 16.6 0.1 2.3 2 1 1 3 3 3 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 AAG03421.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.17 AAG03421.1 - 0.019 13.6 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) LysR_substrate PF03466.20 AAG03422.1 - 1.5e-37 129.0 7.0 2.1e-37 128.5 7.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03422.1 - 4e-24 84.3 1.4 6.8e-24 83.6 1.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAG03422.1 - 0.00022 20.7 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAG03422.1 - 0.0017 18.2 0.7 0.0039 17.1 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAG03422.1 - 0.0036 17.3 0.2 0.0093 16.0 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAG03422.1 - 0.012 15.4 0.5 0.043 13.6 0.2 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_5 PF01022.20 AAG03422.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_AsnC-type PF13404.6 AAG03422.1 - 0.016 15.0 0.1 0.043 13.7 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG03422.1 - 0.036 14.0 0.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 AAG03422.1 - 0.052 13.7 0.3 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 AAG03422.1 - 0.087 12.8 0.1 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 MarR family LytTR PF04397.15 AAG03422.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 LytTr DNA-binding domain Hpt PF01627.23 AAG03423.1 - 3e-09 37.0 6.3 4.5e-09 36.4 6.3 1.3 1 0 0 1 1 1 1 Hpt domain DUF4332 PF14229.6 AAG03423.1 - 0.0009 19.5 1.8 0.0012 19.1 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) DUF1241 PF06840.11 AAG03423.1 - 0.061 13.0 0.1 0.071 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Response_reg PF00072.24 AAG03424.1 - 7.1e-30 103.5 0.0 1.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG03424.1 - 6e-24 83.4 0.1 9.9e-24 82.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG03424.1 - 0.00038 20.1 0.2 0.00067 19.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG03424.1 - 0.00073 19.0 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG03424.1 - 0.0042 16.8 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AAG03424.1 - 0.022 14.9 0.0 0.067 13.3 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AAG03424.1 - 0.052 13.6 0.1 0.18 11.9 0.0 2.0 2 1 0 2 2 2 0 Winged helix-turn helix HTH_24 PF13412.6 AAG03424.1 - 0.064 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 AAG03424.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAG03424.1 - 0.17 11.3 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Terminase_5 PF06056.12 AAG03424.1 - 0.17 11.8 0.1 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) CaMKII_AD PF08332.10 AAG03424.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Trp_syntA PF00290.20 AAG03425.1 - 6.9e-105 349.6 0.0 7.8e-105 349.4 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PcrB PF01884.17 AAG03425.1 - 6.1e-06 25.9 0.3 2.1e-05 24.1 0.3 1.8 2 0 0 2 2 2 1 PcrB family His_biosynth PF00977.21 AAG03425.1 - 1.8e-05 24.3 0.2 3.8e-05 23.2 0.1 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein PALP PF00291.25 AAG03426.1 - 2.5e-46 158.5 0.3 3.2e-46 158.1 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LysR_substrate PF03466.20 AAG03427.1 - 7.4e-22 77.7 13.7 7.4e-22 77.7 13.7 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03427.1 - 2.6e-18 65.7 2.3 2.6e-18 65.7 0.5 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG03427.1 - 0.0096 15.8 2.6 0.013 15.4 0.2 2.4 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 AAG03427.1 - 0.024 14.2 0.1 0.48 10.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAG03427.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_50 PF18024.1 AAG03427.1 - 0.11 12.1 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 AAG03427.1 - 1.7 8.5 6.5 4.8 7.1 0.0 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain Dodecin PF07311.12 AAG03428.1 - 2.7e-31 107.6 0.4 3e-31 107.5 0.4 1.0 1 0 0 1 1 1 1 Dodecin DUF1161 PF06649.12 AAG03429.1 - 1.9e-24 85.6 1.9 2.2e-24 85.4 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1161) ShlB PF03865.13 AAG03430.1 - 5.8e-98 328.2 10.4 7e-98 327.9 10.4 1.1 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AAG03430.1 - 4.3e-28 97.0 0.1 5.4e-27 93.4 0.1 2.3 2 0 0 2 2 2 1 POTRA domain, ShlB-type POTRA_3 PF17287.2 AAG03430.1 - 3.1e-15 55.4 0.2 1.1e-14 53.6 0.1 2.1 2 0 0 2 2 2 1 POTRA domain POTRA PF07244.15 AAG03430.1 - 0.0073 16.9 0.0 0.055 14.0 0.0 2.3 2 0 0 2 2 2 1 Surface antigen variable number repeat Fil_haemagg PF05594.14 AAG03431.1 - 1.3e-59 198.7 554.6 3e-08 34.1 2.1 43.5 11 5 22 34 34 34 20 Haemagluttinin repeat DUF637 PF04830.13 AAG03431.1 - 5.7e-47 159.7 14.7 5.7e-47 159.7 14.7 4.1 4 0 0 4 4 4 1 Possible hemagglutinin (DUF637) Haemagg_act PF05860.13 AAG03431.1 - 1.8e-34 118.2 4.5 6.6e-34 116.4 4.5 2.1 1 0 0 1 1 1 1 haemagglutination activity domain Fil_haemagg_2 PF13332.6 AAG03431.1 - 8.1e-15 55.4 22.4 1.1e-09 38.6 4.2 13.8 9 4 4 15 15 15 4 Hemagglutinin repeat CdiA_C PF18451.1 AAG03431.1 - 1.8e-10 40.9 0.0 2.5e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 Contact-dependent growth inhibition CdiA C-terminal domain CAP_assoc_N PF14504.6 AAG03432.1 - 0.044 13.5 0.9 0.061 13.1 0.7 1.5 1 1 0 1 1 1 0 CAP-associated N-terminal Ig_2 PF13895.6 AAG03432.1 - 0.14 12.5 0.8 0.2 12.0 0.8 1.2 1 0 0 1 1 1 0 Immunoglobulin domain DUF4010 PF13194.6 AAG03433.1 - 4.2e-61 206.3 15.9 4.2e-61 206.3 15.9 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4010) MgtC PF02308.16 AAG03433.1 - 2.5e-18 66.6 10.1 2.5e-18 66.6 10.1 3.0 3 1 0 3 3 3 1 MgtC family Spore_YhaL PF14147.6 AAG03433.1 - 0.087 12.5 0.8 0.27 11.0 0.8 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL Methyltrans_RNA PF04452.14 AAG03433.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase YopE PF03545.13 AAG03434.1 - 2.3e-34 117.4 2.6 4.7e-34 116.4 2.6 1.6 1 0 0 1 1 1 1 Yersinia virulence determinant (YopE) ADPrib_exo_Tox PF03496.14 AAG03434.1 - 3e-31 108.3 0.0 4.1e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme ART PF01129.18 AAG03434.1 - 2e-05 24.0 0.0 7.6e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase YopE_N PF09020.10 AAG03434.1 - 0.0055 17.0 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 YopE, N terminal ACT PF01842.25 AAG03434.1 - 0.22 11.3 1.3 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 ACT domain CsgG PF03783.14 AAG03435.1 - 1.1e-30 106.5 0.4 1.3e-30 106.3 0.4 1.1 1 0 0 1 1 1 1 Curli production assembly/transport component CsgG TolB_N PF04052.13 AAG03435.1 - 1.9e-06 28.0 0.0 3.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 TolB amino-terminal domain LpoB PF13036.6 AAG03435.1 - 0.00048 20.1 0.6 0.011 15.6 0.6 2.7 1 1 0 1 1 1 1 Peptidoglycan-synthase activator LpoB DUF4810 PF16068.5 AAG03436.1 - 2.9e-32 111.0 1.5 3.5e-32 110.8 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4810) DUF799 PF05643.11 AAG03437.1 - 3.4e-74 248.5 0.4 3.8e-74 248.3 0.4 1.0 1 0 0 1 1 1 1 Putative bacterial lipoprotein (DUF799) DUF4136 PF13590.6 AAG03437.1 - 0.03 14.9 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) FAA_hydrolase PF01557.18 AAG03437.1 - 0.083 12.5 0.8 0.21 11.2 0.8 1.7 1 1 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family HTH_3 PF01381.22 AAG03438.1 - 1.7e-11 44.0 0.0 3.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAG03438.1 - 6.9e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAG03438.1 - 1.7e-07 31.5 0.7 1.7e-07 31.5 0.7 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain MerR PF00376.23 AAG03438.1 - 0.00084 19.1 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein HTH_37 PF13744.6 AAG03438.1 - 0.0041 17.1 1.1 0.0045 16.9 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 AAG03438.1 - 0.005 16.7 0.1 0.0095 15.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAG03438.1 - 0.025 14.1 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AAG03438.1 - 0.029 14.1 1.4 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain MerR_1 PF13411.6 AAG03438.1 - 0.051 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein Sigma70_r4 PF04545.16 AAG03438.1 - 0.054 13.0 2.4 0.078 12.5 0.2 2.3 3 1 1 4 4 4 0 Sigma-70, region 4 MarR PF01047.22 AAG03438.1 - 0.089 12.7 0.1 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 MarR family Phage_CI_repr PF07022.13 AAG03438.1 - 0.12 12.4 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain HTH_50 PF18024.1 AAG03438.1 - 0.14 11.8 1.4 16 5.2 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Asn_synthase PF00733.21 AAG03441.1 - 7.7e-82 275.8 0.6 1.3e-81 275.0 0.1 1.6 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.6 AAG03441.1 - 1.9e-43 147.3 0.0 3.5e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAG03441.1 - 7.2e-38 129.8 0.0 1.2e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF1933 PF09147.10 AAG03441.1 - 0.033 13.8 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) DUF3700 PF12481.8 AAG03441.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein Cupin_2 PF07883.11 AAG03442.1 - 0.00012 21.7 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain T2SSN PF01203.19 AAG03442.1 - 0.044 14.0 0.1 0.054 13.7 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein N Fic PF02661.18 AAG03443.1 - 0.0004 21.2 0.3 0.0013 19.6 0.1 1.8 2 0 0 2 2 2 1 Fic/DOC family PTS_2-RNA PF01885.16 AAG03444.1 - 2.5e-36 125.4 0.0 3.1e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1993 PF09351.10 AAG03445.1 - 6.4e-66 221.4 0.0 7.2e-66 221.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) LysR_substrate PF03466.20 AAG03446.1 - 3.2e-48 163.9 5.6 5.3e-48 163.2 5.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03446.1 - 1.1e-17 63.7 1.2 1.1e-17 63.7 1.2 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_29 PF13551.6 AAG03446.1 - 0.0068 16.4 1.7 0.038 14.0 0.3 2.9 4 0 0 4 4 4 1 Winged helix-turn helix MarR_2 PF12802.7 AAG03446.1 - 0.011 15.6 0.3 0.15 12.0 0.1 2.9 3 0 0 3 3 3 0 MarR family HemN_C PF06969.16 AAG03446.1 - 0.014 15.4 0.1 0.3 11.2 0.0 2.7 2 0 0 2 2 2 0 HemN C-terminal domain HTH_11 PF08279.12 AAG03446.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 AAG03446.1 - 0.016 14.7 0.1 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Phage_NinH PF06322.11 AAG03446.1 - 0.021 14.7 0.1 0.076 12.9 0.0 1.9 2 0 0 2 2 2 0 Phage NinH protein HTH_8 PF02954.19 AAG03446.1 - 0.039 13.7 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 AAG03446.1 - 0.043 14.0 0.7 0.2 11.8 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_45 PF14947.6 AAG03446.1 - 0.043 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_IclR PF09339.10 AAG03446.1 - 0.049 13.4 1.9 0.14 12.0 0.0 2.7 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_3 PF01381.22 AAG03446.1 - 0.066 13.3 0.5 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix Lactamase_B PF00753.27 AAG03447.1 - 1e-12 48.5 0.0 1.4e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PH_8 PF15409.6 AAG03447.1 - 0.2 11.9 0.3 0.46 10.8 0.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain DSBA PF01323.20 AAG03448.1 - 2.6e-06 27.3 0.0 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 DSBA-like thioredoxin domain OsmC PF02566.19 AAG03449.1 - 5.6e-20 71.7 0.1 7.3e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 OsmC-like protein MORN PF02493.20 AAG03449.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 MORN repeat DUF1161 PF06649.12 AAG03450.1 - 7.6e-25 86.9 1.0 9e-25 86.6 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1161) LPAM_1 PF08139.12 AAG03452.1 - 0.0053 17.2 1.9 0.0084 16.5 1.9 1.3 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site Aminopep PF10023.9 AAG03453.1 - 1.1e-133 445.5 0.6 1.3e-133 445.3 0.6 1.0 1 0 0 1 1 1 1 Putative aminopeptidase Peptidase_M1 PF01433.20 AAG03453.1 - 0.015 14.9 0.1 0.033 13.8 0.1 1.5 1 1 0 1 1 1 0 Peptidase family M1 domain HAD_2 PF13419.6 AAG03455.1 - 1.2e-25 90.6 0.0 1.4e-25 90.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG03455.1 - 6.2e-12 45.4 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 AAG03455.1 - 7.1e-12 46.1 0.0 1.9e-10 41.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG03455.1 - 9.7e-12 45.7 0.6 1.3e-11 45.2 0.6 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAG03455.1 - 6.4e-05 22.8 0.0 1.1 9.0 0.0 3.0 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Hexapep PF00132.24 AAG03456.1 - 1.9e-17 62.2 3.9 1.9e-06 27.4 1.2 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAG03456.1 - 7.3e-06 25.6 10.4 0.0014 18.3 4.2 3.9 2 2 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Peptidase_M3 PF01432.20 AAG03457.1 - 4.8e-150 500.8 0.0 6.7e-150 500.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 OrfB_IS605 PF01385.19 AAG03457.1 - 0.19 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Probable transposase Peptidase_M50B PF13398.6 AAG03457.1 - 0.57 9.8 1.9 1.2 8.7 1.9 1.5 1 0 0 1 1 1 0 Peptidase M50B-like DUF2387 PF09526.10 AAG03458.1 - 1.2e-36 124.7 0.4 1.3e-36 124.5 0.4 1.0 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.7 AAG03458.1 - 0.0077 16.2 0.9 0.014 15.3 1.0 1.4 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Radical_SAM PF04055.21 AAG03459.1 - 3.5e-14 53.5 1.6 3.1e-13 50.5 1.6 2.1 1 1 0 1 1 1 1 Radical SAM superfamily DUF1848 PF08902.11 AAG03459.1 - 0.042 13.6 2.5 0.35 10.5 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) Gly-zipper_Omp PF13488.6 AAG03460.1 - 3.5e-07 30.1 15.6 7.2e-07 29.1 15.6 1.6 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 AAG03460.1 - 2e-05 24.3 20.5 4.1e-05 23.2 20.5 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 AAG03460.1 - 4e-05 23.4 19.2 9.3e-05 22.2 19.2 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Tim17 PF02466.19 AAG03460.1 - 0.24 11.8 5.3 1.3 9.5 4.9 2.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 AAG03460.1 - 0.67 10.1 5.5 5 7.3 0.2 2.7 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III DUF745 PF05335.13 AAG03460.1 - 1.1 8.9 8.4 0.14 11.8 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FGE-sulfatase PF03781.16 AAG03461.1 - 2.6e-30 105.9 0.0 4.2e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 SpoIIE PF07228.12 AAG03461.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) MacB_PCD PF12704.7 AAG03462.1 - 5.1e-06 27.0 0.1 9.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 AAG03462.1 - 5.5e-05 23.6 3.5 5.5e-05 23.6 3.5 2.8 3 0 0 3 3 3 1 FtsX-like permease family ABC_tran PF00005.27 AAG03463.1 - 7.5e-25 88.0 0.0 1e-24 87.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG03463.1 - 8.3e-11 42.2 0.0 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG03463.1 - 6.9e-06 25.6 0.0 0.056 12.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG03463.1 - 1.3e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG03463.1 - 2.9e-05 24.5 2.3 7.6e-05 23.2 2.2 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AAG03463.1 - 0.00024 21.7 0.0 0.00036 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAG03463.1 - 0.00048 19.7 0.8 0.0012 18.4 0.8 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAG03463.1 - 0.00062 19.7 0.0 0.00093 19.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AAG03463.1 - 0.00072 19.8 0.2 0.0061 16.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAG03463.1 - 0.0017 18.3 0.0 0.011 15.7 0.0 2.2 3 0 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 AAG03463.1 - 0.0025 17.7 0.0 0.0099 15.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 AAG03463.1 - 0.0028 17.4 0.2 0.19 11.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAG03463.1 - 0.016 15.3 0.1 0.064 13.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAG03463.1 - 0.018 15.3 0.4 0.15 12.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 AAG03463.1 - 0.027 14.8 0.0 0.037 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 AAG03463.1 - 0.045 13.8 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AAG03463.1 - 0.077 13.5 0.0 0.21 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG03463.1 - 0.12 12.0 0.0 1.6 8.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 AAG03463.1 - 0.21 10.3 0.0 7.1 5.3 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 AAG03463.1 - 0.25 11.4 0.0 0.48 10.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pkinase PF00069.25 AAG03464.1 - 2.9e-50 171.1 0.0 4.4e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAG03464.1 - 3.5e-36 124.8 0.0 6.4e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TssR PF17643.1 AAG03464.1 - 3.8e-06 25.2 0.0 3.1e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 Type VI secretion system, TssR VWA PF00092.28 AAG03464.1 - 6.8e-06 26.4 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain APH PF01636.23 AAG03464.1 - 9.6e-06 25.7 2.2 0.094 12.6 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family VWA_2 PF13519.6 AAG03464.1 - 0.00032 21.3 0.1 0.0016 19.1 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Pkinase_fungal PF17667.1 AAG03464.1 - 0.00043 19.2 0.0 0.00067 18.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AAG03464.1 - 0.006 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 AAG03464.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWA_CoxE PF05762.14 AAG03464.1 - 0.1 12.0 0.0 7 6.0 0.0 2.5 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein PP2C_2 PF13672.6 AAG03465.1 - 1e-11 44.9 0.3 1.5e-11 44.3 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 AAG03465.1 - 4.3e-06 26.8 1.0 1.6e-05 24.9 1.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 AAG03465.1 - 3.3e-05 23.6 0.0 8.1e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C TagF_N PF09867.9 AAG03466.1 - 1.2e-47 161.4 0.0 1.7e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 TagF N-terminal domain, Type VI secretion system-associated ImcF-related_N PF14331.6 AAG03467.1 - 1.2e-99 332.9 3.9 1.5e-99 332.5 1.6 2.3 2 0 0 2 2 2 1 ImcF-related N-terminal domain IcmF-related PF06761.12 AAG03467.1 - 2.7e-86 289.9 3.5 2.7e-86 289.9 3.5 2.3 2 0 0 2 2 2 1 Intracellular multiplication and human macrophage-killing IcmF_C PF06744.12 AAG03467.1 - 1.1e-69 234.1 0.2 2.5e-69 233.0 0.2 1.6 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal RHH_1 PF01402.21 AAG03467.1 - 0.011 15.6 0.3 0.24 11.4 0.0 3.3 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family AAA_22 PF13401.6 AAG03467.1 - 0.15 12.4 1.2 1.1 9.5 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 AAG03467.1 - 0.17 12.1 3.5 2.6 8.3 0.1 3.8 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AAG03467.1 - 2.3 8.6 5.5 3.7 7.9 0.2 3.6 3 1 0 3 3 3 0 AAA ATPase domain DotU PF09850.9 AAG03468.1 - 4.4e-69 232.3 2.5 7.5e-69 231.5 2.5 1.4 1 0 0 1 1 1 1 Type VI secretion system protein DotU OmpA PF00691.20 AAG03468.1 - 9.2e-15 54.8 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 OmpA family DUF883 PF05957.13 AAG03468.1 - 0.0043 17.6 3.0 0.1 13.2 0.0 3.6 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF883) T6SS_VasE PF05936.12 AAG03469.1 - 4.3e-160 533.1 0.0 4.9e-160 532.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE T6SS-SciN PF12790.7 AAG03470.1 - 1.1e-40 138.0 0.0 1.4e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 FHA PF00498.26 AAG03471.1 - 3.7e-15 56.0 0.0 5.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 AAG03471.1 - 6.9e-06 26.3 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF2076 PF09849.9 AAG03471.1 - 7.5 6.5 11.4 20 5.1 11.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ImpA_N PF06812.12 AAG03472.1 - 3e-34 117.7 0.2 8e-34 116.3 0.0 1.8 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system Disulph_isomer PF06491.11 AAG03472.1 - 0.078 13.1 0.2 6.5 6.9 0.1 2.2 2 0 0 2 2 2 0 Disulphide isomerase T6SS_VipA PF05591.12 AAG03473.1 - 3.9e-58 195.6 0.2 4.4e-58 195.5 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Herpes_UL69 PF05459.12 AAG03473.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family VipB PF05943.12 AAG03474.1 - 3.6e-190 632.2 0.0 4.2e-190 632.0 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath TssC PF17541.2 AAG03474.1 - 0.28 10.0 1.2 0.5 9.1 1.2 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB T6SS_HCP PF05638.12 AAG03475.1 - 1.3e-43 148.5 0.1 1.5e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImpE PF07024.13 AAG03476.1 - 8.7e-44 148.5 0.1 1.4e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 ImpE protein TPR_19 PF14559.6 AAG03476.1 - 6e-06 26.7 0.8 6e-06 26.7 0.8 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAG03476.1 - 5.5e-05 23.7 0.3 5.5e-05 23.7 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAG03476.1 - 0.00065 20.3 1.4 0.00065 20.3 1.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 AAG03476.1 - 0.0071 16.8 3.1 0.0094 16.4 0.3 2.4 2 1 0 2 2 2 1 Bacterial transcriptional activator domain GPW_gp25 PF04965.14 AAG03477.1 - 9e-22 76.7 0.0 1.7e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Gene 25-like lysozyme T6SS_TssF PF05947.12 AAG03478.1 - 1.2e-239 796.9 0.1 1.3e-239 796.8 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF T6SS_TssG PF06996.11 AAG03479.1 - 1.4e-107 359.4 0.4 1.6e-107 359.2 0.4 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG AAA_2 PF07724.14 AAG03480.1 - 5.7e-39 134.0 0.0 2e-38 132.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAG03480.1 - 1.5e-28 98.8 2.6 3.2e-28 97.7 1.6 2.1 2 0 0 2 2 1 1 AAA lid domain AAA PF00004.29 AAG03480.1 - 1.1e-18 67.9 0.1 2.4e-09 37.7 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AAG03480.1 - 2.7e-13 49.8 0.0 1.5e-12 47.4 0.0 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AAG03480.1 - 3.6e-12 46.5 0.7 5.2e-09 36.2 0.0 3.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAG03480.1 - 2.9e-09 37.5 17.9 5.6e-07 30.1 0.3 5.9 4 2 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 AAG03480.1 - 5.3e-07 29.5 0.1 7.6e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 AAG03480.1 - 5.4e-06 26.0 0.0 0.0095 15.4 0.0 3.9 4 1 0 4 4 4 1 Bacterial TniB protein AAA_22 PF13401.6 AAG03480.1 - 6.2e-06 26.5 3.9 0.035 14.4 0.1 5.1 4 1 0 5 5 4 1 AAA domain AAA_7 PF12775.7 AAG03480.1 - 9.2e-05 22.0 0.0 0.45 10.0 0.2 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 AAG03480.1 - 0.00013 21.4 0.7 0.0017 17.7 0.0 3.0 4 0 0 4 4 4 1 Zeta toxin ATPase_2 PF01637.18 AAG03480.1 - 0.00013 22.0 0.1 0.2 11.5 0.0 3.0 3 0 0 3 3 2 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AAG03480.1 - 0.00015 21.4 8.3 0.019 14.6 0.1 3.7 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 AAG03480.1 - 0.0015 18.3 0.0 2.4 7.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 AAG03480.1 - 0.002 18.1 0.5 0.35 10.8 0.0 3.2 2 1 0 2 2 2 1 NACHT domain ResIII PF04851.15 AAG03480.1 - 0.0025 17.8 0.1 3.4 7.6 0.1 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Clp_N PF02861.20 AAG03480.1 - 0.0025 17.9 0.0 0.079 13.1 0.0 3.0 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component Torsin PF06309.11 AAG03480.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_18 PF13238.6 AAG03480.1 - 0.003 18.1 2.3 0.11 13.1 0.1 3.2 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 AAG03480.1 - 0.0081 16.2 0.0 3.7 7.6 0.0 3.1 2 1 1 3 3 2 1 AAA domain CbiA PF01656.23 AAG03480.1 - 0.012 15.7 0.3 0.091 12.8 0.1 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 AAG03480.1 - 0.013 15.5 0.1 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Hpr_kinase_C PF07475.12 AAG03480.1 - 0.023 14.2 0.9 0.18 11.4 0.1 2.6 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 AAG03480.1 - 0.023 14.4 0.1 7.3 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 AAG03480.1 - 0.043 13.5 0.0 7 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 AAG03480.1 - 0.048 13.3 0.2 0.51 9.9 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 AAG03480.1 - 0.063 13.2 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 AAG03480.1 - 0.085 12.8 0.5 11 5.9 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 AAG03480.1 - 0.14 12.5 2.8 5 7.5 1.0 3.3 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 AAG03480.1 - 0.2 10.8 0.0 23 4.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 AAG03480.1 - 0.24 11.8 0.0 27 5.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 AAG03480.1 - 0.31 11.5 1.4 48 4.4 1.0 3.2 3 0 0 3 3 3 0 AAA domain M PF02370.16 AAG03480.1 - 0.8 10.5 4.0 2.2 9.1 2.5 2.7 2 0 0 2 2 1 0 M protein repeat ABC_tran_CTD PF16326.5 AAG03480.1 - 9.8 6.5 16.7 16 5.9 7.6 3.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain Phage_GPD PF05954.11 AAG03481.1 - 3.6e-104 348.3 0.2 5.1e-104 347.8 0.2 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Phage_base_V PF04717.12 AAG03481.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector Tsi6 PF18660.1 AAG03482.1 - 8e-32 109.1 0.0 8.8e-32 109.0 0.0 1.0 1 0 0 1 1 1 1 Tsi6 Ntox46 PF15538.6 AAG03483.1 - 2.3e-97 323.3 0.5 3.2e-97 322.9 0.5 1.2 1 0 0 1 1 1 1 Bacterial toxin 46 PAAR_motif PF05488.13 AAG03483.1 - 1.2e-12 47.8 5.4 2.7e-12 46.7 0.0 3.2 3 1 0 3 3 3 1 PAAR motif DUF4150 PF13665.6 AAG03483.1 - 0.045 13.9 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) DcrB PF08786.11 AAG03484.1 - 1.8e-34 118.6 0.0 2e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 DcrB Phage_GPD PF05954.11 AAG03485.1 - 1.2e-105 353.2 1.0 2.2e-105 352.3 1.0 1.5 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Gp5_C PF06715.12 AAG03485.1 - 3.4e-27 92.6 47.5 2.7e-05 24.0 4.5 8.7 3 1 8 12 12 12 10 Gp5 C-terminal repeat (3 copies) DUF2345 PF10106.9 AAG03485.1 - 0.0046 16.8 2.5 2.2 8.1 0.4 3.1 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) MspA PF09203.11 AAG03485.1 - 0.61 9.9 7.4 3 7.7 7.4 2.0 1 1 0 1 1 1 0 MspA DUF2345 PF10106.9 AAG03486.1 - 0.073 12.9 0.4 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF2169 PF09937.9 AAG03487.1 - 4e-93 312.1 0.4 4.8e-93 311.8 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2169) ketoacyl-synt PF00109.26 AAG03488.1 - 0.00049 19.7 0.4 0.00094 18.8 0.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AAG03488.1 - 0.0038 17.1 0.1 0.02 14.8 0.1 2.1 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Tox-GHH2 PF15635.6 AAG03489.1 - 3.4e-43 146.7 4.3 3.4e-43 146.7 4.3 1.7 2 0 0 2 2 2 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 DUF4150 PF13665.6 AAG03489.1 - 1.1e-36 125.3 0.4 2.3e-36 124.2 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4150) DUF4423 PF14394.6 AAG03489.1 - 0.12 12.0 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HEAT_2 PF13646.6 AAG03491.1 - 2.9e-14 53.2 16.9 1.8e-07 31.4 0.2 4.2 5 0 0 5 5 5 3 HEAT repeats Pro_CA PF00484.19 AAG03492.1 - 1.5e-50 171.5 0.2 2e-50 171.1 0.2 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Flp_Fap PF04964.14 AAG03492.1 - 0.048 13.5 0.1 0.088 12.6 0.1 1.3 1 0 0 1 1 1 0 Flp/Fap pilin component Sulfate_transp PF00916.20 AAG03493.1 - 5.7e-63 212.9 15.2 7.6e-63 212.5 15.2 1.2 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 AAG03493.1 - 2.1e-07 31.3 5.5 2.1e-07 31.3 5.5 4.6 4 1 0 4 4 4 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 AAG03493.1 - 4.1e-06 27.0 0.1 4.1e-06 27.0 0.1 2.8 3 0 0 3 3 3 1 STAS domain HCO3_cotransp PF00955.21 AAG03493.1 - 1.7 7.4 8.9 0.22 10.3 1.3 2.6 2 1 1 3 3 3 0 HCO3- transporter family COX2 PF00116.20 AAG03495.1 - 6.5e-37 126.1 0.1 1.2e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 AAG03495.1 - 4.4e-13 49.2 2.8 7.8e-13 48.4 2.8 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Cytochrome_CBB3 PF13442.6 AAG03495.1 - 5.4e-11 42.7 0.1 1.3e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG03495.1 - 3.2e-06 28.2 1.7 8.4e-05 23.6 0.7 2.8 2 1 0 2 2 2 1 Cytochrome c Yip1 PF04893.17 AAG03495.1 - 0.0036 17.1 0.4 0.0047 16.7 0.4 1.3 1 0 0 1 1 1 1 Yip1 domain Cytochrom_C1 PF02167.15 AAG03495.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C1 family COX1 PF00115.20 AAG03496.1 - 1.2e-152 508.8 83.9 1.3e-152 508.6 83.9 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Flavi_NS4B PF01349.17 AAG03496.1 - 0.0058 16.0 4.2 0.0058 16.0 4.2 1.8 2 0 0 2 2 2 1 Flavivirus non-structural protein NS4B CtaG_Cox11 PF04442.14 AAG03497.1 - 1.1e-49 168.4 0.0 1.3e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 COX3 PF00510.18 AAG03498.1 - 1.5e-53 182.3 23.0 2.4e-50 171.8 23.0 2.0 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Jagunal PF07086.12 AAG03498.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.6 3 0 0 3 3 3 0 Jagunal, ER re-organisation during oogenesis DUF3487 PF11990.8 AAG03498.1 - 0.4 10.6 0.1 0.4 10.6 0.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3487) DUF2909 PF11137.8 AAG03499.1 - 1.5e-20 72.8 5.9 1.7e-20 72.7 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2909) Phage_holin_3_6 PF07332.11 AAG03499.1 - 0.066 13.3 5.8 0.069 13.2 5.8 1.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SURF1 PF02104.15 AAG03500.1 - 1e-31 110.6 0.6 1.3e-31 110.2 0.6 1.1 1 0 0 1 1 1 1 SURF1 family COX15-CtaA PF02628.15 AAG03502.1 - 1.2e-82 277.6 25.3 1.4e-82 277.4 25.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein UbiA PF01040.18 AAG03503.1 - 3.5e-60 203.4 26.6 4.2e-60 203.2 26.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family SCO1-SenC PF02630.14 AAG03504.1 - 2.6e-43 147.1 0.0 3.2e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AAG03504.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AAG03504.1 - 2.6e-06 27.6 0.0 1.2e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AAG03504.1 - 2.6e-05 24.0 0.0 3.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin Acetyltransf_10 PF13673.7 AAG03505.1 - 8.8e-15 54.8 0.0 1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG03505.1 - 1.7e-09 38.0 0.0 2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG03505.1 - 6.3e-07 29.7 0.1 9.7e-07 29.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAG03505.1 - 0.00013 22.1 0.2 0.00042 20.4 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG03505.1 - 0.00076 19.6 0.1 0.0023 18.0 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase HxlR PF01638.17 AAG03506.1 - 3e-23 81.5 0.0 4.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR_2 PF12802.7 AAG03506.1 - 0.021 14.7 0.3 0.042 13.8 0.3 1.5 1 1 0 1 1 1 0 MarR family PadR PF03551.14 AAG03506.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Zn_ribbon_recom PF13408.6 AAG03506.1 - 0.084 13.4 0.8 0.39 11.3 0.0 2.3 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain Ogr_Delta PF04606.12 AAG03506.1 - 0.18 11.8 1.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger adh_short PF00106.25 AAG03507.1 - 2.1e-34 118.7 0.0 2.5e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG03507.1 - 3.8e-27 95.4 0.0 4.4e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG03507.1 - 1.7e-05 24.8 0.6 4.7e-05 23.4 0.6 1.7 1 1 1 2 2 2 1 KR domain Shikimate_DH PF01488.20 AAG03507.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AAG03507.1 - 0.15 11.9 0.2 0.98 9.3 0.3 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DSBA PF01323.20 AAG03508.1 - 2.5e-44 151.4 0.0 2.8e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AAG03508.1 - 0.034 14.3 0.0 0.045 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_5 PF13743.6 AAG03508.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin SDF PF00375.18 AAG03509.1 - 2.1e-97 326.6 36.7 2.4e-97 326.4 36.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5433 PF17498.2 AAG03509.1 - 1.6 9.0 4.8 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5433) FCD PF07729.12 AAG03510.1 - 1.2e-28 100.0 5.1 2.2e-28 99.2 5.1 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAG03510.1 - 3.5e-17 61.8 2.3 4.5e-17 61.5 0.9 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AAG03510.1 - 0.00099 19.0 0.1 0.0039 17.1 0.0 2.0 2 0 0 2 2 2 1 HTH domain Rrf2 PF02082.20 AAG03510.1 - 0.0062 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator DUF1315 PF07023.12 AAG03510.1 - 0.0087 16.1 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1315) HTH_24 PF13412.6 AAG03510.1 - 0.016 14.7 0.2 0.054 13.1 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAG03510.1 - 0.021 14.8 0.1 0.045 13.7 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 AAG03510.1 - 0.031 14.1 1.9 0.29 11.0 0.2 3.0 2 1 1 3 3 3 0 IclR helix-turn-helix domain HrcA_DNA-bdg PF03444.15 AAG03510.1 - 0.084 12.5 0.1 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_28 PF13518.6 AAG03510.1 - 0.1 12.7 0.2 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain PSII_Pbs31 PF18240.1 AAG03510.1 - 0.18 12.2 0.0 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Photosystem II Psb31 protein FCD PF07729.12 AAG03511.1 - 7.8e-17 61.9 8.6 8.4e-17 61.8 7.4 1.7 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 AAG03511.1 - 8.3e-10 38.2 0.0 2.8e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family PreAtp-grasp PF18604.1 AAG03511.1 - 0.01 15.5 0.2 0.021 14.5 0.2 1.7 1 0 0 1 1 1 0 Pre ATP-grasp domain HTH_41 PF14502.6 AAG03511.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG03511.1 - 0.031 14.3 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAG03511.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 HTH domain Fe_dep_repress PF01325.19 AAG03511.1 - 0.088 13.0 0.0 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_DeoR PF08220.12 AAG03511.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain PadR PF03551.14 AAG03511.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Aegerolysin PF06355.13 AAG03512.1 - 3.3e-44 150.1 0.3 3.7e-44 150.0 0.3 1.0 1 0 0 1 1 1 1 Aegerolysin LysR_substrate PF03466.20 AAG03513.1 - 8.5e-41 139.6 5.5 8.5e-41 139.6 5.5 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03513.1 - 1.2e-20 73.2 1.8 2.9e-20 72.0 1.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG03513.1 - 0.0013 18.5 0.2 0.0057 16.5 0.2 2.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAG03513.1 - 0.0043 16.6 0.1 0.017 14.7 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding P22_Cro PF14549.6 AAG03513.1 - 0.029 14.2 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_30 PF13556.6 AAG03513.1 - 0.045 13.5 0.2 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 AAG03513.1 - 0.053 13.4 0.6 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 AAG03513.1 - 0.1 12.6 1.0 0.24 11.4 0.4 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain ParE_toxin PF05016.15 AAG03514.1 - 4.2e-08 33.7 0.1 5.1e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE RHH_1 PF01402.21 AAG03515.1 - 4.5e-12 45.4 0.4 4.5e-12 45.4 0.4 1.5 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family STAT_int PF02865.17 AAG03515.1 - 0.00021 21.7 0.1 0.00024 21.5 0.1 1.1 1 0 0 1 1 1 1 STAT protein, protein interaction domain RHH_3 PF12651.7 AAG03515.1 - 0.12 12.4 0.1 0.4 10.7 0.0 2.0 2 1 0 2 2 2 0 Ribbon-helix-helix domain LEA_2 PF03168.13 AAG03517.1 - 7.5e-22 77.8 0.0 9.9e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Late embryogenesis abundant protein PhnA PF03831.14 AAG03518.1 - 5.6e-33 112.6 9.5 6.7e-33 112.4 9.5 1.1 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 AAG03518.1 - 1.6e-17 63.2 6.0 2.8e-17 62.4 6.0 1.4 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 AAG03518.1 - 0.003 17.0 0.5 0.003 17.0 0.5 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding zf-RRN7 PF11781.8 AAG03518.1 - 0.0075 15.9 4.6 0.021 14.5 3.9 2.1 2 1 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 AAG03518.1 - 0.054 13.4 2.5 0.78 9.7 2.5 2.5 1 1 0 1 1 1 0 zinc-ribbon domain Prok-RING_1 PF14446.6 AAG03518.1 - 0.055 13.4 0.3 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2318 PF10080.9 AAG03518.1 - 0.083 13.0 0.2 0.12 12.5 0.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) PADR1 PF08063.12 AAG03518.1 - 0.11 12.3 4.0 0.87 9.4 4.0 2.1 1 1 0 1 1 1 0 PADR1 (NUC008) domain TFIIS_C PF01096.18 AAG03518.1 - 0.19 11.6 2.0 6.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) UPF0547 PF10571.9 AAG03518.1 - 0.41 10.8 0.1 0.41 10.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 AAG03518.1 - 1.1 9.4 5.8 12 6.1 1.3 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-NADH-PPase PF09297.11 AAG03518.1 - 2.5 7.8 4.5 16 5.2 0.1 2.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain AA_permease PF00324.21 AAG03519.1 - 2.1e-117 392.7 41.3 2.5e-117 392.4 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG03519.1 - 3.4e-44 151.3 45.4 4e-44 151.1 45.4 1.0 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 AAG03520.1 - 5.2e-140 467.0 0.0 5.9e-140 466.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAG03520.1 - 0.16 11.0 0.0 0.6 9.1 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Cupin_2 PF07883.11 AAG03521.1 - 6.9e-08 32.1 1.9 8.5e-08 31.8 1.5 1.4 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 AAG03521.1 - 0.0098 15.6 0.1 0.013 15.2 0.1 1.3 1 1 0 1 1 1 1 Auxin binding protein Aminotran_3 PF00202.21 AAG03522.1 - 1e-78 264.8 0.0 1.2e-78 264.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAG03522.1 - 0.027 13.8 0.0 0.064 12.5 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase LysR_substrate PF03466.20 AAG03523.1 - 1.9e-25 89.5 1.9 2.8e-25 88.9 1.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03523.1 - 9.4e-17 60.7 0.1 4.1e-16 58.7 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Amidohydro_1 PF01979.20 AAG03524.1 - 2.9e-64 217.6 0.0 3.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG03524.1 - 1.2e-07 31.6 3.8 5.6e-05 22.8 0.1 2.4 1 1 0 2 2 2 2 Amidohydrolase family ABC_tran PF00005.27 AAG03526.1 - 2.1e-42 144.9 0.0 1.6e-33 116.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAG03526.1 - 9.3e-07 28.9 0.1 0.00092 19.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAG03526.1 - 0.0039 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AAG03526.1 - 0.037 13.6 0.0 0.91 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAG03526.1 - 0.042 14.1 0.1 0.21 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAG03526.1 - 0.044 13.7 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AAG03526.1 - 0.047 14.2 0.0 0.072 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAG03526.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 AAG03526.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal AAA_15 PF13175.6 AAG03526.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 AAG03526.1 - 0.22 11.6 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain BPD_transp_2 PF02653.16 AAG03527.1 - 2e-47 161.6 27.2 2e-47 161.6 27.2 1.7 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component LapA_dom PF06305.11 AAG03527.1 - 0.0096 15.7 0.6 0.0096 15.7 0.6 3.8 5 1 1 6 6 6 1 Lipopolysaccharide assembly protein A domain BPD_transp_2 PF02653.16 AAG03528.1 - 4e-38 131.1 46.5 5.1e-38 130.8 46.5 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component AhpC-TSA PF00578.21 AAG03529.1 - 3.3e-30 104.5 0.0 4.3e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG03529.1 - 2.3e-12 46.9 0.0 2.9e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AAG03529.1 - 9.9e-08 31.7 0.1 2.4e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 AAG03529.1 - 0.0083 16.0 0.0 0.016 15.1 0.0 1.6 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA_2 PF13911.6 AAG03529.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme THUMP PF02926.17 AAG03529.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 THUMP domain Pyr_redox_2 PF07992.14 AAG03530.1 - 4.9e-48 163.9 2.1 7.3e-48 163.3 1.7 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG03530.1 - 1.2e-20 74.0 0.4 1.1e-16 61.0 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG03530.1 - 7.8e-15 55.2 7.0 2.5e-12 47.2 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG03530.1 - 5.7e-11 42.1 7.9 0.0011 18.2 4.3 3.5 2 1 0 3 3 3 3 Glucose inhibited division protein A Thioredoxin_3 PF13192.6 AAG03530.1 - 5.7e-09 35.9 0.0 1.9e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin domain FAD_binding_2 PF00890.24 AAG03530.1 - 1.9e-07 30.5 18.4 0.01 15.0 5.7 4.4 2 2 3 5 5 5 2 FAD binding domain HI0933_like PF03486.14 AAG03530.1 - 2.4e-07 29.8 8.0 0.062 12.0 2.0 3.4 3 0 0 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.7 AAG03530.1 - 5.8e-05 22.6 17.6 9.4e-05 21.9 6.0 3.2 2 2 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAG03530.1 - 9.5e-05 21.8 2.7 0.048 12.9 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 AAG03530.1 - 0.0004 20.1 12.7 0.054 13.1 3.6 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAG03530.1 - 0.00058 19.2 3.1 0.0049 16.1 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain Glutaredoxin PF00462.24 AAG03530.1 - 0.0011 19.2 0.3 0.0054 16.9 0.0 2.4 3 0 0 3 3 2 1 Glutaredoxin K_oxygenase PF13434.6 AAG03530.1 - 0.0019 17.4 0.2 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 AAG03530.1 - 0.0064 16.9 3.0 0.79 10.2 0.0 2.7 3 0 0 3 3 2 1 Putative NAD(P)-binding Thi4 PF01946.17 AAG03530.1 - 0.0097 15.2 4.2 0.039 13.2 0.1 2.6 2 1 1 3 3 3 1 Thi4 family FMO-like PF00743.19 AAG03530.1 - 0.017 13.5 0.0 0.027 12.9 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 AAG03530.1 - 0.023 14.9 6.3 0.081 13.2 1.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thioredoxin_4 PF13462.6 AAG03530.1 - 0.2 11.8 0.1 1.4 9.1 0.0 2.1 1 1 0 2 2 2 0 Thioredoxin Trp_halogenase PF04820.14 AAG03530.1 - 1.9 7.2 7.6 9.8 4.9 0.2 2.5 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.6 AAG03530.1 - 5.6 6.9 8.7 9.8 6.2 0.0 3.5 4 0 0 4 4 3 0 FAD-NAD(P)-binding PPK2 PF03976.14 AAG03531.1 - 5e-112 373.0 1.0 6e-112 372.7 1.0 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) MeaB PF03308.16 AAG03531.1 - 0.039 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Toprim_3 PF13362.6 AAG03531.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Toprim domain Amidohydro_1 PF01979.20 AAG03532.1 - 3.3e-60 204.2 0.0 3.9e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG03532.1 - 5.8e-11 42.5 2.7 4e-09 36.5 0.1 2.3 1 1 1 2 2 2 2 Amidohydrolase family IU_nuc_hydro PF01156.19 AAG03533.2 - 1.2e-87 294.3 0.0 1.5e-87 294.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Nuc_deoxyrib_tr PF05014.15 AAG03534.1 - 1.9e-49 167.0 0.0 2.3e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 AAG03534.1 - 0.0086 16.4 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like TAT_signal PF10518.9 AAG03534.1 - 0.039 13.8 2.6 0.13 12.1 2.6 2.0 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Nuc_deoxyrib_tr PF05014.15 AAG03535.1 - 1.7e-48 163.9 0.0 2e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 AAG03535.1 - 0.028 14.7 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Bmp PF02608.14 AAG03536.1 - 1.3e-52 178.7 0.0 2.2e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like DIOX_N PF14226.6 AAG03537.1 - 3.6e-32 111.6 0.0 5.9e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 AAG03537.1 - 4.2e-25 88.2 0.0 6.7e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily A_deaminase PF00962.22 AAG03538.1 - 1.8e-72 244.4 0.0 2.3e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Isochorismatase PF00857.20 AAG03538.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Isochorismatase family Sigma70_r4_2 PF08281.12 AAG03539.1 - 2.7e-16 59.0 0.4 4.8e-16 58.2 0.4 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG03539.1 - 4.9e-15 55.1 0.4 9.3e-15 54.2 0.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG03539.1 - 1.8e-10 40.2 0.3 3.7e-10 39.2 0.3 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 KORA PF16509.5 AAG03539.1 - 0.00064 20.0 0.0 0.0016 18.6 0.0 1.6 2 0 0 2 2 2 1 TrfB plasmid transcriptional repressor Sigma70_ECF PF07638.11 AAG03539.1 - 0.0019 18.1 1.4 0.0026 17.7 1.4 1.4 1 1 0 1 1 1 1 ECF sigma factor HTH_40 PF14493.6 AAG03539.1 - 0.012 16.0 0.1 0.031 14.7 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 AAG03539.1 - 0.028 14.5 3.0 0.065 13.3 0.2 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 AAG03539.1 - 0.037 14.2 2.9 0.042 14.0 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 AAG03539.1 - 0.069 13.0 1.0 0.19 11.5 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Spo0A_C PF08769.11 AAG03539.1 - 0.076 13.1 0.1 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal GerE PF00196.19 AAG03539.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF2774 PF11242.8 AAG03539.1 - 0.17 12.1 0.0 0.66 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) FecR PF04773.13 AAG03540.1 - 1.9e-18 66.9 0.1 3e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG03540.1 - 9.5e-12 44.6 11.1 9.5e-12 44.6 11.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AAG03540.1 - 8.7e-06 25.7 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) GrpB PF04229.14 AAG03540.1 - 0.17 12.1 0.1 0.28 11.4 0.1 1.2 1 0 0 1 1 1 0 GrpB protein TonB_dep_Rec PF00593.24 AAG03541.1 - 9.7e-69 233.4 14.9 1.4e-68 232.9 14.9 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG03541.1 - 2.1e-16 60.4 0.9 4.4e-16 59.4 0.9 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG03541.1 - 1.9e-07 30.7 0.0 1.8e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Secretin and TonB N terminus short domain T3SS_ExsE PF18286.1 AAG03541.1 - 0.061 13.3 0.5 0.79 9.7 0.3 3.0 3 0 0 3 3 3 0 Type III secretion system ExsE LysR_substrate PF03466.20 AAG03542.1 - 1e-32 113.2 8.2 1.3e-32 112.9 8.2 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03542.1 - 1.3e-11 44.3 0.3 5.1e-11 42.4 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family OpuAC PF04069.12 AAG03542.1 - 0.097 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system DUF4954 PF16314.5 AAG03542.1 - 0.26 9.3 0.0 0.35 8.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Dioxygenase_C PF00775.21 AAG03543.1 - 5.8e-57 192.1 0.0 7e-57 191.8 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase PCDO_beta_N PF12391.8 AAG03543.1 - 5.5e-15 54.7 2.0 1.2e-14 53.6 2.0 1.5 1 0 0 1 1 1 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal CarboxypepD_reg PF13620.6 AAG03543.1 - 6.8e-05 23.1 0.0 0.00017 21.8 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 AAG03543.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain Dioxygenase_C PF00775.21 AAG03544.1 - 3.6e-13 49.3 0.0 2.4e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 Dioxygenase IclR PF01614.18 AAG03545.1 - 2.3e-38 131.0 0.1 3.2e-37 127.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AAG03545.1 - 9.8e-15 54.1 0.8 2.3e-14 52.9 0.8 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_9 PF08221.11 AAG03545.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain Rrf2 PF02082.20 AAG03545.1 - 0.002 18.4 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 AAG03545.1 - 0.0071 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 AAG03545.1 - 0.0084 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR_2 PF12802.7 AAG03545.1 - 0.011 15.6 0.9 0.024 14.5 0.2 1.9 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 AAG03545.1 - 0.017 14.7 0.0 0.044 13.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cullin PF00888.22 AAG03545.1 - 0.033 12.8 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Cullin family HTH_5 PF01022.20 AAG03545.1 - 0.043 13.7 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AAG03545.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 HTH domain HlyD_D23 PF16576.5 AAG03546.1 - 9.7e-17 60.9 4.1 1.7e-16 60.1 4.1 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG03546.1 - 4.9e-14 52.9 7.8 5.8e-11 43.0 0.6 3.0 3 1 1 4 4 4 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG03546.1 - 5.5e-07 29.3 5.8 5.5e-07 29.3 5.8 3.0 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG03546.1 - 0.00014 21.6 0.1 0.087 12.7 0.0 3.0 2 0 0 2 2 2 2 Biotin-requiring enzyme OEP PF02321.18 AAG03546.1 - 0.0056 16.5 15.4 0.012 15.4 15.4 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein YqfD PF06898.11 AAG03546.1 - 0.18 10.6 0.2 0.47 9.2 0.1 1.7 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD HlyD_D23 PF16576.5 AAG03547.1 - 3.3e-17 62.4 0.8 5.9e-17 61.6 0.8 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG03547.1 - 5.1e-14 52.9 0.9 3.1e-11 43.9 0.1 2.8 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG03547.1 - 1.2e-08 34.7 12.9 3.2e-05 23.7 0.2 4.0 4 0 0 4 4 4 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG03547.1 - 0.031 14.1 0.0 0.84 9.5 0.0 2.6 2 0 0 2 2 2 0 Biotin-requiring enzyme Borrelia_P83 PF05262.11 AAG03547.1 - 0.056 11.9 1.1 0.079 11.4 1.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ACR_tran PF00873.19 AAG03548.1 - 3.9e-157 524.8 1.5 4.8e-157 524.4 1.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family LysR_substrate PF03466.20 AAG03549.1 - 8.2e-44 149.5 3.4 8.2e-44 149.5 3.4 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03549.1 - 8.3e-19 67.3 3.3 3.7e-18 65.2 3.4 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 AAG03549.1 - 0.076 12.4 0.1 0.076 12.4 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 OprD PF03573.13 AAG03552.1 - 2.4e-152 507.6 6.4 2.7e-152 507.4 6.4 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family HTH_18 PF12833.7 AAG03553.1 - 7.3e-19 67.8 1.4 1.5e-18 66.9 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG03553.1 - 9.2e-11 41.6 0.1 2.8e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG03553.1 - 1.7e-07 31.2 0.0 3.7e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG03553.1 - 0.0022 17.7 0.0 0.005 16.5 0.0 1.6 2 0 0 2 2 2 1 Cupin domain HTH_Crp_2 PF13545.6 AAG03553.1 - 0.0027 17.6 0.4 0.0087 16.0 0.4 1.9 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_31 PF13560.6 AAG03553.1 - 0.034 14.5 1.2 0.21 12.0 1.3 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain PuR_N PF09182.10 AAG03553.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal G_glu_transpept PF01019.21 AAG03554.1 - 7e-159 529.9 0.0 8.1e-159 529.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Channel_Tsx PF03502.13 AAG03555.1 - 5e-18 65.8 10.1 6.6e-18 65.4 10.1 1.2 1 0 0 1 1 1 1 Nucleoside-specific channel-forming protein, Tsx Xan_ur_permease PF00860.20 AAG03556.1 - 3.1e-85 286.2 36.1 4e-85 285.9 36.1 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 AAG03556.1 - 0.0009 19.6 2.2 0.0009 19.6 2.2 4.0 3 2 1 4 4 4 1 Molybdate transporter of MFS superfamily TetR_C_3 PF08362.11 AAG03557.1 - 1.3e-53 180.8 0.0 1.9e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 AAG03557.1 - 2.7e-13 49.5 0.1 6e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 AAG03557.1 - 0.0059 16.7 0.0 0.0082 16.2 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_9 PF14514.6 AAG03557.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UPF0029 PF01205.19 AAG03558.1 - 9.7e-27 93.4 0.0 1.3e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 AAG03558.1 - 1.4e-12 47.3 0.3 2.1e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1949) GGDEF PF00990.21 AAG03559.1 - 2.2e-45 154.3 0.1 4.4e-45 153.3 0.0 1.5 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAG03559.1 - 0.0091 16.2 0.2 0.017 15.3 0.2 1.6 1 0 0 1 1 1 1 GGDEF-like domain DUF1987 PF09345.10 AAG03560.1 - 9.9e-40 135.0 0.0 1.1e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1987) DUF1048 PF06304.11 AAG03560.1 - 0.01 16.3 0.0 4.9 7.7 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1048) RIH_assoc PF08454.11 AAG03560.1 - 0.037 13.9 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 RyR and IP3R Homology associated MCM PF00493.23 AAG03561.1 - 0.032 13.3 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain Monellin PF09200.10 AAG03561.1 - 0.13 12.1 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 Monellin SpoIIE PF07228.12 AAG03562.1 - 8.5e-25 87.8 0.7 1.2e-24 87.3 0.1 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) HAMP PF00672.25 AAG03562.1 - 4.9e-14 52.4 0.4 1.1e-13 51.4 0.4 1.6 1 0 0 1 1 1 1 HAMP domain dCache_1 PF02743.18 AAG03562.1 - 0.00027 20.8 0.1 0.00066 19.6 0.0 1.7 2 0 0 2 2 2 1 Cache domain CheB_methylest PF01339.17 AAG03563.1 - 1.8e-62 210.0 0.0 2.9e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.24 AAG03563.1 - 5.1e-23 81.4 0.0 1.8e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain SelB-wing_2 PF09106.11 AAG03563.1 - 1.2 9.3 4.8 13 6.1 0.3 3.2 3 0 0 3 3 3 0 Elongation factor SelB, winged helix CheD PF03975.13 AAG03564.1 - 1.1e-31 109.2 0.0 1.6e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 CheD chemotactic sensory transduction YdfA_immunity PF12127.8 AAG03564.1 - 0.18 10.8 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial CheR PF01739.18 AAG03565.1 - 5.5e-56 189.1 0.0 7e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAG03565.1 - 6.1e-16 57.9 2.2 1.4e-15 56.7 2.2 1.6 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 AAG03565.1 - 5.1e-05 23.9 0.0 0.0023 18.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG03565.1 - 0.00062 20.5 0.0 0.0091 16.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG03565.1 - 0.018 15.7 0.0 0.15 12.8 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain MCPsignal PF00015.21 AAG03566.1 - 1e-55 188.2 36.2 3.3e-54 183.3 22.8 3.3 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP_N3 PF18575.1 AAG03566.1 - 1.3e-21 75.9 3.4 3.6e-18 64.9 0.1 5.5 6 0 0 6 6 6 1 HAMP N-terminal domain 3 PAS_8 PF13188.7 AAG03566.1 - 1.3e-05 25.1 0.1 5.7e-05 23.0 0.1 2.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAG03566.1 - 0.0001 22.5 0.9 0.0006 20.0 0.2 2.7 2 1 0 2 2 1 1 PAS fold PAS_9 PF13426.7 AAG03566.1 - 0.0063 16.8 0.0 0.035 14.4 0.0 2.4 2 1 0 2 2 2 1 PAS domain PAS_7 PF12860.7 AAG03566.1 - 0.038 14.1 0.1 0.038 14.1 0.1 3.1 3 1 0 3 3 3 0 PAS fold IFT57 PF10498.9 AAG03566.1 - 0.038 13.0 8.9 0.027 13.5 0.8 2.8 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 PAS PF00989.25 AAG03566.1 - 0.041 13.9 0.1 0.19 11.8 0.1 2.2 1 0 0 1 1 1 0 PAS fold HAMP PF00672.25 AAG03566.1 - 0.042 14.2 16.5 0.51 10.8 0.1 7.5 6 3 1 7 7 6 0 HAMP domain MnmE_helical PF12631.7 AAG03566.1 - 0.084 13.0 21.0 0.16 12.1 0.4 3.3 2 1 0 3 3 3 0 MnmE helical domain Tweety PF04906.13 AAG03566.1 - 0.26 9.9 9.7 0.057 12.1 2.0 2.5 2 0 0 2 2 2 0 Tweety BLOC1_2 PF10046.9 AAG03566.1 - 0.28 11.5 16.2 5 7.5 0.6 4.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 AAG03566.1 - 0.7 7.8 9.3 0.19 9.7 1.5 3.3 2 1 1 3 3 3 0 Prominin DUF1664 PF07889.12 AAG03566.1 - 2.2 8.3 18.7 4.6 7.3 2.5 5.2 3 3 2 5 5 5 0 Protein of unknown function (DUF1664) FTA4 PF13093.6 AAG03566.1 - 3.4 7.5 7.5 0.43 10.4 0.2 2.8 3 1 0 3 3 3 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fez1 PF06818.15 AAG03566.1 - 3.5 8.0 15.7 27 5.2 0.1 3.4 2 1 0 2 2 2 0 Fez1 tRNA_bind_2 PF13725.6 AAG03566.1 - 5.3 6.7 9.6 0.53 9.9 1.7 2.5 2 0 0 2 2 2 0 Possible tRNA binding domain Spc7 PF08317.11 AAG03566.1 - 5.6 5.7 15.4 1.1 8.0 2.3 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein Mod_r PF07200.13 AAG03566.1 - 6.8 6.8 11.8 1.8 8.6 1.5 3.6 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CheW PF01584.19 AAG03567.1 - 1.9e-35 121.5 0.5 2.2e-35 121.3 0.5 1.0 1 0 0 1 1 1 1 CheW-like domain CheW PF01584.19 AAG03568.1 - 1.3e-26 92.9 1.1 2.2e-26 92.1 1.1 1.4 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AAG03568.1 - 1e-21 77.0 0.6 1e-21 77.0 0.6 2.3 2 0 0 2 2 2 1 Hpt domain H-kinase_dim PF02895.14 AAG03568.1 - 2.6e-18 66.2 0.7 5.8e-18 65.1 0.7 1.6 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c PF02518.26 AAG03568.1 - 1.7e-16 60.7 0.0 4.2e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAG03568.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 AAG03569.1 - 1.8e-29 102.2 0.0 2e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAG03569.1 - 0.0068 16.8 0.0 0.008 16.5 0.0 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ MCPsignal PF00015.21 AAG03570.1 - 2.5e-28 99.0 9.7 4.3e-28 98.3 7.6 2.1 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 AAG03570.1 - 0.026 14.6 4.9 11 6.1 0.7 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 AAG03570.1 - 0.44 10.9 5.6 4 7.8 1.5 3.5 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 AAG03570.1 - 0.45 10.4 2.5 2.9 7.8 0.0 3.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 HalX PF08663.10 AAG03570.1 - 2.4 8.5 8.0 0.52 10.7 0.5 3.4 3 1 0 3 3 3 0 HalX domain LysR_substrate PF03466.20 AAG03571.1 - 2.4e-38 131.6 0.0 3.2e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03571.1 - 6.6e-19 67.6 1.1 1.1e-18 67.0 1.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG03571.1 - 0.0054 16.6 0.1 0.023 14.5 0.0 2.1 2 0 0 2 2 2 1 MarR family adh_short_C2 PF13561.6 AAG03572.1 - 3e-61 207.0 5.0 3.6e-61 206.7 5.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG03572.1 - 1.3e-52 178.1 1.2 1.8e-52 177.6 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG03572.1 - 9.2e-10 38.7 1.8 1.2e-09 38.3 1.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG03572.1 - 0.00025 20.6 0.2 0.00038 20.0 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AAG03572.1 - 0.0068 16.0 0.7 0.032 13.8 1.4 1.8 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.17 AAG03572.1 - 0.029 14.9 1.4 0.059 14.0 1.4 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GHMP_kinases_C PF08544.13 AAG03572.1 - 0.093 13.1 2.5 0.15 12.5 1.0 2.1 2 0 0 2 2 2 0 GHMP kinases C terminal DUF1776 PF08643.10 AAG03572.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sulfatase PF00884.23 AAG03573.1 - 7.5e-92 308.0 0.0 8.9e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 AAG03573.1 - 0.0016 17.2 0.0 0.0023 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 AAG03573.1 - 0.013 16.3 0.0 0.68 10.7 0.0 2.3 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 AAG03573.1 - 0.038 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF4994 PF16385.5 AAG03573.1 - 0.06 13.3 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function ABC_tran PF00005.27 AAG03574.1 - 1.3e-31 109.9 0.0 1.9e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG03574.1 - 9.2e-07 29.0 1.4 0.0015 18.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 AAG03574.1 - 5.5e-05 22.2 0.3 0.013 14.3 0.0 2.7 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 AAG03574.1 - 0.00025 20.7 0.0 0.076 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAG03574.1 - 0.00032 21.0 0.3 0.0011 19.2 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG03574.1 - 0.0004 20.8 0.8 0.0011 19.4 0.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG03574.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAG03574.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAG03574.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 AAG03574.1 - 0.0054 17.0 0.1 0.029 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 AAG03574.1 - 0.012 15.9 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 AAG03574.1 - 0.02 15.4 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAG03574.1 - 0.026 13.7 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SMC_N PF02463.19 AAG03574.1 - 0.026 13.9 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AAG03574.1 - 0.036 14.2 0.4 0.18 11.9 0.4 2.0 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAG03574.1 - 0.053 13.5 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 AAG03574.1 - 0.062 13.2 0.2 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 AAG03574.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 AAG03574.1 - 0.092 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 AAG03574.1 - 0.099 13.2 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAG03574.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PRK PF00485.18 AAG03574.1 - 0.19 11.4 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.18 AAG03574.1 - 0.22 11.2 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase BPD_transp_1 PF00528.22 AAG03575.1 - 9.5e-37 126.5 39.5 1.8e-19 70.2 12.2 2.6 3 0 0 3 3 3 2 Binding-protein-dependent transport system inner membrane component NMT1 PF09084.11 AAG03576.1 - 1.8e-19 70.5 0.0 2.6e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAG03576.1 - 5.8e-11 42.6 0.0 4.7e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAG03576.1 - 7.8e-08 32.2 0.1 2e-07 30.9 0.1 1.7 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 AAG03576.1 - 1.1e-07 31.6 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAG03576.1 - 0.00014 21.4 0.0 0.00029 20.3 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 YhfZ_C PF14503.6 AAG03576.1 - 0.016 14.7 0.0 0.042 13.4 0.0 1.6 1 1 0 1 1 1 0 YhfZ C-terminal domain TauD PF02668.16 AAG03577.1 - 1.1e-34 120.4 0.0 1.4e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 AAG03577.1 - 1.7e-06 27.4 0.0 2.6e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 CsiD Mem_trans PF03547.18 AAG03578.1 - 9.5e-16 57.2 21.3 1.3e-10 40.2 9.3 2.0 1 1 1 2 2 2 2 Membrane transport protein OprD PF03573.13 AAG03579.1 - 1.7e-140 468.5 2.6 2e-140 468.3 2.6 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family PAP2 PF01569.21 AAG03580.1 - 1.6e-12 47.4 0.0 2.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 PAP2 superfamily LysR_substrate PF03466.20 AAG03581.1 - 7.2e-32 110.4 0.3 8.9e-32 110.1 0.3 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03581.1 - 2.9e-22 78.4 0.4 6.7e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family TonB_dep_Rec PF00593.24 AAG03582.1 - 1.4e-39 137.3 29.5 1.4e-39 137.3 29.5 1.8 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG03582.1 - 4.3e-14 53.0 3.7 6.2e-14 52.5 0.5 2.7 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG03582.1 - 1.5e-05 24.1 0.1 0.00082 18.4 0.0 2.3 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family TauD PF02668.16 AAG03583.1 - 5.4e-54 183.8 2.0 6.3e-54 183.6 2.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cupin_2 PF07883.11 AAG03583.1 - 0.085 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Cupin domain TauD PF02668.16 AAG03584.1 - 4e-55 187.5 0.1 4.7e-55 187.2 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PNTB PF02233.16 AAG03585.1 - 5.1e-191 635.6 23.9 5.8e-191 635.4 23.9 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 AAG03585.1 - 0.00054 19.7 0.2 0.0052 16.5 0.2 2.6 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TonB_C PF03544.14 AAG03586.1 - 2e-24 85.8 0.0 5.4e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAG03586.1 - 9e-05 22.6 0.0 9e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 TonB C terminal MotA_ExbB PF01618.16 AAG03587.1 - 7.5e-36 122.7 0.2 1.1e-35 122.2 0.2 1.3 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family Chlorosome_CsmC PF11098.8 AAG03587.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF937 PF06078.11 AAG03587.1 - 0.61 10.7 6.1 0.14 12.8 2.5 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) ExbD PF02472.16 AAG03588.1 - 3.9e-28 98.2 0.7 4.3e-28 98.1 0.7 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DUF2149 PF09919.9 AAG03588.1 - 0.52 10.6 2.8 0.88 9.9 2.8 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF3079 PF11278.8 AAG03589.1 - 6.7e-34 115.5 3.4 8.8e-34 115.1 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3079) Ser_hydrolase PF06821.13 AAG03590.1 - 6.4e-69 231.2 2.6 7.3e-69 231.0 2.6 1.0 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 AAG03590.1 - 9.3e-08 32.9 7.5 5.2e-06 27.2 2.9 2.8 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG03590.1 - 3.8e-06 26.3 0.0 0.00037 19.9 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG03590.1 - 4.3e-06 26.6 0.0 0.017 14.8 0.0 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold FSH1 PF03959.13 AAG03590.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF1749 PF08538.10 AAG03590.1 - 0.0091 15.1 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_4 PF08386.10 AAG03590.1 - 0.014 15.5 0.1 0.18 12.0 0.0 2.5 1 1 2 3 3 3 0 TAP-like protein Amidase PF01425.21 AAG03591.1 - 2.3e-85 287.3 0.0 6.4e-85 285.8 0.0 1.6 1 1 0 1 1 1 1 Amidase SBP_bac_8 PF13416.6 AAG03592.1 - 3.3e-26 92.8 0.0 3.9e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03592.1 - 2.2e-17 63.3 0.0 3.5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03592.1 - 1.7e-16 61.1 0.2 2.6e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG03592.1 - 4e-11 43.1 0.0 4.9e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAG03592.1 - 0.00027 19.8 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical lipoprotein (MG045 family) BPD_transp_1 PF00528.22 AAG03593.1 - 1.7e-11 44.2 16.2 1.7e-11 44.2 16.2 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component UPF0242 PF06785.11 AAG03593.1 - 0.47 10.5 0.9 0.9 9.6 0.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BPD_transp_1 PF00528.22 AAG03594.1 - 6.8e-15 55.3 16.1 6.8e-15 55.3 16.1 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAG03595.1 - 8.7e-34 117.0 0.0 3.1e-33 115.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter TOBE_2 PF08402.10 AAG03595.1 - 6.6e-16 58.2 0.2 1.7e-15 56.9 0.0 1.8 2 0 0 2 2 1 1 TOBE domain AAA_21 PF13304.6 AAG03595.1 - 9.8e-11 42.0 0.1 1.5e-06 28.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG03595.1 - 4e-05 23.2 0.0 0.0037 16.7 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG03595.1 - 9.8e-05 22.6 0.4 0.001 19.3 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAG03595.1 - 0.00074 20.0 0.2 0.079 13.4 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG03595.1 - 0.002 18.5 0.6 0.012 16.0 0.6 2.1 1 1 0 1 1 1 1 AAA ATPase domain TOBE PF03459.17 AAG03595.1 - 0.0077 16.5 0.1 0.44 10.9 0.0 2.5 2 0 0 2 2 2 1 TOBE domain AAA_23 PF13476.6 AAG03595.1 - 0.013 16.1 0.0 0.028 14.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 AAG03595.1 - 0.015 15.5 0.5 0.32 11.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAG03595.1 - 0.016 14.8 0.1 1.2 8.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAG03595.1 - 0.016 15.1 0.0 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 AAG03595.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 AAG03595.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 AAG03595.1 - 0.043 14.1 0.1 0.99 9.7 0.2 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 AAG03595.1 - 0.076 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain sCache_3_2 PF17203.4 AAG03595.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Single cache domain 3 AAA_5 PF07728.14 AAG03595.1 - 0.12 12.4 0.2 0.5 10.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AAG03595.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AAG03595.1 - 0.18 11.5 0.3 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AAG03595.1 - 0.26 10.4 0.0 0.48 9.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.6 AAG03595.1 - 0.3 10.8 0.0 0.44 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain LysR_substrate PF03466.20 AAG03596.1 - 3.3e-31 108.3 4.4 3.3e-31 108.3 4.4 2.0 2 0 0 2 2 2 2 LysR substrate binding domain HTH_1 PF00126.27 AAG03596.1 - 1.1e-20 73.3 1.2 1.1e-20 73.3 1.2 2.7 4 0 0 4 4 4 1 Bacterial regulatory helix-turn-helix protein, lysR family Mal_decarbox_Al PF16957.5 AAG03597.1 - 1.8e-294 977.2 0.0 2.1e-294 977.0 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter CitG PF01874.16 AAG03598.1 - 1.5e-73 247.9 9.6 1.9e-73 247.5 9.6 1.1 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase ACP PF06857.11 AAG03599.1 - 3.6e-26 91.2 0.0 4.1e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase delta subunit (MdcD) Carboxyl_trans PF01039.22 AAG03600.1 - 9.7e-15 54.2 0.0 1.2e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAG03601.1 - 6.5e-101 336.7 1.7 7.3e-101 336.5 1.7 1.0 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) Carboxyl_trans PF01039.22 AAG03601.1 - 0.0033 16.1 0.1 0.004 15.8 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcG PF10620.9 AAG03602.1 - 3.1e-55 187.1 5.9 3.6e-55 186.9 5.9 1.0 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG NTP_transf_2 PF01909.23 AAG03602.1 - 0.24 11.7 0.0 0.37 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase domain Acyl_transf_1 PF00698.21 AAG03603.1 - 2.7e-28 99.4 0.0 4e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 AAG03603.1 - 0.00029 20.6 1.1 0.054 13.2 0.6 2.6 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FANC_SAP PF18081.1 AAG03603.1 - 4.9 7.4 9.1 3.5 7.9 0.2 4.2 4 0 0 4 4 4 0 Fanconi anemia-associated nuclease SAP domain MadL PF03817.13 AAG03604.1 - 2.5e-50 169.4 11.2 2.8e-50 169.2 11.2 1.0 1 0 0 1 1 1 1 Malonate transporter MadL subunit SNARE_assoc PF09335.11 AAG03604.1 - 0.059 13.9 9.4 1.6 9.2 3.8 2.3 1 1 1 2 2 2 0 SNARE associated Golgi protein FliP PF00813.20 AAG03604.1 - 0.12 12.3 0.3 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 FliP family DUF2207 PF09972.9 AAG03604.1 - 2.6 6.7 8.4 2.5 6.8 3.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MadM PF03818.13 AAG03605.1 - 5.4e-26 90.2 5.1 5.4e-26 90.2 5.1 3.1 3 0 0 3 3 3 1 Malonate/sodium symporter MadM subunit LysR_substrate PF03466.20 AAG03606.1 - 2.2e-35 121.9 0.2 3.2e-35 121.4 0.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03606.1 - 3.6e-13 49.2 0.3 8.2e-13 48.1 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAG03607.1 - 6.7e-43 146.5 0.1 8.5e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03607.1 - 9.9e-20 70.3 0.0 2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Aldedh PF00171.22 AAG03608.1 - 3.5e-168 559.9 0.0 4.1e-168 559.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AAG03608.1 - 0.019 14.4 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) AA_permease_2 PF13520.6 AAG03609.1 - 2.1e-38 132.3 30.1 2.5e-38 132.0 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAG03609.1 - 8.3e-28 97.2 32.8 1.1e-27 96.8 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease Glycophorin_A PF01102.18 AAG03609.1 - 0.11 12.8 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Aminotran_3 PF00202.21 AAG03610.1 - 7.3e-82 275.2 0.0 9e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAG03610.1 - 0.016 14.5 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase SBP_bac_8 PF13416.6 AAG03611.1 - 8.3e-42 143.9 1.0 1.1e-41 143.6 1.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03611.1 - 2.5e-18 66.4 0.4 4.1e-18 65.7 0.4 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03611.1 - 2.7e-09 37.4 7.6 4.9e-09 36.6 7.6 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG03611.1 - 0.0013 18.5 3.7 0.0013 18.5 3.7 1.6 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein DHDPS PF00701.22 AAG03612.1 - 3.7e-55 186.7 0.0 4.2e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldolase_II PF00596.21 AAG03613.1 - 3.8e-38 131.3 0.0 4.7e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HTH_3 PF01381.22 AAG03614.1 - 1.1e-16 60.6 1.1 1.6e-16 60.1 1.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Cupin_2 PF07883.11 AAG03614.1 - 9.4e-14 50.9 0.2 1.4e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 Cupin domain HTH_31 PF13560.6 AAG03614.1 - 2.1e-13 50.4 0.0 3.6e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG03614.1 - 2.6e-11 43.3 0.2 4.1e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAG03614.1 - 1.1e-05 25.8 0.1 2.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_35 PF13693.6 AAG03614.1 - 6.7e-05 22.9 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_25 PF13413.6 AAG03614.1 - 0.00056 19.7 0.1 0.0014 18.4 0.1 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AAG03614.1 - 0.00099 19.0 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain CoA_trans PF01144.23 AAG03615.1 - 1.7e-24 86.4 0.0 2.1e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme A transferase Mal_decarbox_Al PF16957.5 AAG03615.1 - 0.23 9.7 0.0 0.57 8.5 0.0 1.6 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter CoA_trans PF01144.23 AAG03616.1 - 1.5e-48 165.1 0.0 1.7e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase Thiolase_N PF00108.23 AAG03617.1 - 4.1e-79 265.6 0.0 5e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG03617.1 - 3.7e-43 146.1 0.3 7.4e-43 145.1 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG03617.1 - 8.4e-06 25.5 1.0 4.8e-05 23.1 0.4 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Sugar_tr PF00083.24 AAG03618.1 - 7.1e-35 120.7 33.5 3.3e-24 85.6 11.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAG03618.1 - 8.7e-29 100.5 46.3 1.1e-17 64.0 19.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAG03618.1 - 7.8e-07 28.0 33.7 2.9e-06 26.1 15.6 3.7 2 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 AAG03618.1 - 0.00066 18.7 15.7 0.01 14.7 6.9 3.6 1 1 3 4 4 4 3 MFS_1 like family AzlD PF05437.12 AAG03618.1 - 0.0039 17.3 0.5 0.0039 17.3 0.5 4.1 4 2 1 5 5 5 1 Branched-chain amino acid transport protein (AzlD) DUF4231 PF14015.6 AAG03618.1 - 1.4 9.4 5.0 2.8 8.5 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) LacY_symp PF01306.19 AAG03618.1 - 2 7.1 22.0 0.13 11.0 12.1 2.3 1 1 0 2 2 2 0 LacY proton/sugar symporter Lyase_1 PF00206.20 AAG03619.1 - 2.6e-67 227.4 0.0 3.6e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AAG03619.1 - 8.9e-20 71.0 2.1 8.9e-20 71.0 2.1 2.7 4 0 0 4 4 4 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 AAG03619.1 - 0.00073 19.6 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal ASL_C2 PF14698.6 AAG03619.1 - 0.033 15.0 0.2 0.12 13.2 0.2 1.9 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal Abhydrolase_1 PF00561.20 AAG03620.1 - 4.1e-19 69.2 0.3 4.7e-17 62.5 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG03620.1 - 2.3e-13 51.3 7.1 2.8e-13 51.0 7.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG03620.1 - 5.4e-12 45.5 0.1 7.8e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 AAG03620.1 - 0.002 18.2 0.2 0.0088 16.1 0.0 2.1 2 1 0 2 2 2 1 TAP-like protein Ndr PF03096.14 AAG03620.1 - 0.03 13.0 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Ndr family FSH1 PF03959.13 AAG03620.1 - 0.064 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) CMD PF02627.20 AAG03621.1 - 1.9e-24 85.5 0.2 3.3e-24 84.7 0.0 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family LysR_substrate PF03466.20 AAG03622.1 - 8.3e-39 133.1 7.1 1.1e-38 132.8 7.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03622.1 - 1.8e-16 59.9 0.0 4.9e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AAG03622.1 - 0.00048 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAG03622.1 - 0.0018 17.8 0.2 0.0052 16.3 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding UMP1 PF05348.11 AAG03622.1 - 0.034 14.4 0.0 0.095 12.9 0.0 1.8 1 1 0 1 1 1 0 Proteasome maturation factor UMP1 MFS_1 PF07690.16 AAG03624.1 - 3.2e-52 177.6 86.9 2.2e-43 148.5 48.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG03624.1 - 9.3e-26 90.7 29.8 2.3e-24 86.1 5.8 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAG03624.1 - 2.2e-08 33.8 8.7 2.2e-08 33.8 8.7 2.5 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAG03624.1 - 2.5 6.9 26.4 0.063 12.1 5.9 3.0 2 1 0 2 2 2 0 MFS_1 like family IclR PF01614.18 AAG03625.1 - 7.1e-19 67.9 0.0 1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AAG03625.1 - 1.3e-17 63.3 4.6 2.6e-17 62.3 1.6 2.9 3 0 0 3 3 3 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAG03625.1 - 1.2e-08 34.7 0.1 7.8e-07 28.9 0.6 2.8 2 1 0 2 2 2 1 MarR family HTH_24 PF13412.6 AAG03625.1 - 1.4e-07 31.0 0.8 6.3e-07 28.9 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 AAG03625.1 - 2.9e-05 24.5 0.6 7.1e-05 23.2 0.1 1.9 2 0 0 2 2 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AAG03625.1 - 0.00034 20.6 0.6 0.00034 20.6 0.6 2.4 3 0 0 3 3 2 1 Helix-turn-helix domain TrmB PF01978.19 AAG03625.1 - 0.0022 17.9 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAG03625.1 - 0.0029 17.9 0.0 0.0081 16.5 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 AAG03625.1 - 0.0057 16.6 0.0 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 AAG03625.1 - 0.0088 16.0 0.2 0.021 14.7 0.1 1.7 2 0 0 2 2 2 1 HTH domain Fe_dep_repress PF01325.19 AAG03625.1 - 0.0094 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4 PF04545.16 AAG03625.1 - 0.084 12.4 0.0 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 DUF4423 PF14394.6 AAG03625.1 - 0.1 12.3 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) PCI PF01399.27 AAG03625.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 PCI domain HTH_23 PF13384.6 AAG03625.1 - 0.11 12.3 0.8 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain FeoC PF09012.10 AAG03625.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator V_ATPase_prox PF18274.1 AAG03625.1 - 0.18 11.8 2.4 0.82 9.7 0.1 2.8 3 0 0 3 3 2 0 Vacuolar ATPase Subunit I N-terminal proximal lobe Ribosomal_S25 PF03297.15 AAG03625.1 - 0.2 11.9 0.0 4 7.7 0.0 2.1 1 1 1 2 2 2 0 S25 ribosomal protein HTH_Crp_2 PF13545.6 AAG03625.1 - 0.23 11.4 1.7 1.4 8.9 0.1 2.6 3 0 0 3 3 2 0 Crp-like helix-turn-helix domain GFO_IDH_MocA PF01408.22 AAG03626.1 - 1.6e-20 74.1 0.0 3.5e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAG03626.1 - 5.4e-11 42.5 0.0 1.3e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 AAG03626.1 - 0.0033 18.1 0.0 0.0056 17.3 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain DapB_N PF01113.20 AAG03626.1 - 0.23 11.6 0.0 0.51 10.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AP_endonuc_2 PF01261.24 AAG03627.1 - 4.8e-16 58.8 0.5 6.6e-16 58.4 0.5 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF5615 PF18480.1 AAG03627.1 - 0.12 12.1 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) EamA PF00892.20 AAG03628.1 - 1e-23 84.0 33.6 2.8e-15 56.7 13.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family OprD PF03573.13 AAG03629.1 - 5.4e-151 503.1 2.3 6.1e-151 502.9 2.3 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family MFS_1 PF07690.16 AAG03630.1 - 1.7e-51 175.2 42.2 1.7e-51 175.2 42.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.6 AAG03630.1 - 0.0074 16.5 2.0 0.0074 16.5 2.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4381) DUF3742 PF12553.8 AAG03630.1 - 0.61 10.2 8.8 6.6 6.9 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) AP_endonuc_2 PF01261.24 AAG03631.1 - 4.4e-38 130.8 1.4 2.4e-37 128.4 0.4 2.2 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Glyoxalase_5 PF14696.6 AAG03631.1 - 5.5e-37 127.0 0.0 2.2e-36 125.1 0.0 1.9 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.25 AAG03631.1 - 4.2e-10 39.9 0.0 7.1e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG03631.1 - 7e-08 32.7 0.0 0.00013 22.2 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAG03631.1 - 0.02 15.0 0.3 0.19 11.8 0.0 2.6 3 0 0 3 3 3 0 Glyoxalase-like domain TetR_C_29 PF17938.1 AAG03632.1 - 1.6e-46 157.3 0.9 2.5e-46 156.6 0.9 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAG03632.1 - 3.9e-14 52.2 0.4 6.6e-14 51.4 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_21 PF17926.1 AAG03632.1 - 0.0062 16.7 0.1 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 AAG03632.1 - 0.064 13.5 0.1 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 AAG03632.1 - 0.077 12.8 0.6 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain TP6A_N PF04406.14 AAG03632.1 - 0.14 12.2 0.8 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 Type IIB DNA topoisomerase TetR_C_15 PF17918.1 AAG03632.1 - 0.17 12.7 1.3 0.4 11.5 0.0 2.3 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Shikimate_dh_N PF08501.11 AAG03633.1 - 7.5e-22 77.4 0.0 1.8e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AAG03633.1 - 6.7e-05 22.6 1.8 7e-05 22.5 0.3 1.9 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AAG03633.1 - 0.00033 20.7 0.0 0.00064 19.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 AAG03633.1 - 0.0015 18.0 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AAG03633.1 - 0.002 18.4 0.5 0.0061 16.8 0.1 2.0 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 AAG03633.1 - 0.061 12.8 0.1 0.089 12.2 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DHquinase_II PF01220.19 AAG03634.1 - 1.2e-61 206.4 0.0 1.4e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II MFS_1 PF07690.16 AAG03635.1 - 8.5e-55 186.1 44.2 8.5e-55 186.1 44.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG03635.1 - 2e-17 63.2 9.7 2e-17 63.2 9.7 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 AAG03635.1 - 1.5e-10 40.1 17.7 2.4e-10 39.5 17.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 AAG03635.1 - 5e-05 22.0 29.4 0.00064 18.4 5.9 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 AAG03635.1 - 0.00044 19.2 6.0 0.00044 19.2 6.0 2.5 2 1 0 2 2 2 1 MFS_1 like family OATP PF03137.20 AAG03635.1 - 0.0021 16.4 1.8 0.0043 15.4 1.8 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 AAG03635.1 - 0.089 11.4 8.8 0.36 9.4 8.8 2.0 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like FAD_binding_3 PF01494.19 AAG03636.1 - 2.6e-100 336.1 0.0 3e-100 335.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAG03636.1 - 0.00028 21.1 0.1 0.0007 19.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AAG03636.1 - 0.0007 18.9 0.1 0.0015 17.8 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG03636.1 - 0.017 14.4 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 AAG03636.1 - 0.099 11.9 0.1 0.26 10.5 0.1 1.6 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG03636.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein HTH_18 PF12833.7 AAG03637.1 - 8.6e-20 70.8 0.2 8.6e-20 70.8 0.2 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG03637.1 - 2.7e-08 33.7 0.0 8.9e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG03637.1 - 3.3e-08 33.5 0.5 4.6e-08 33.0 0.5 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG03637.1 - 2.9e-05 23.7 0.0 5.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain MarR_2 PF12802.7 AAG03637.1 - 0.0046 16.8 0.0 1.3 9.0 0.0 2.7 1 1 1 2 2 2 1 MarR family TetR_N PF00440.23 AAG03637.1 - 0.0066 16.2 0.0 0.098 12.5 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Cupin_6 PF12852.7 AAG03637.1 - 0.046 13.4 0.7 1.5 8.5 0.7 2.2 1 1 0 1 1 1 0 Cupin Sigma70_r4 PF04545.16 AAG03637.1 - 0.078 12.5 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_1 PF01527.20 AAG03637.1 - 0.089 13.1 0.0 3.4 8.0 0.0 2.5 1 1 1 2 2 2 0 Transposase HTH_24 PF13412.6 AAG03637.1 - 0.1 12.2 0.0 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 AAG03637.1 - 0.12 12.1 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Acetyltransf_7 PF13508.7 AAG03638.1 - 2.8e-15 56.5 0.0 4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG03638.1 - 1.4e-14 54.1 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG03638.1 - 1.9e-12 47.4 0.2 2.8e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AAG03638.1 - 0.0011 18.8 0.1 0.0029 17.6 0.1 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AAG03638.1 - 0.042 14.5 0.0 0.076 13.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG03638.1 - 0.051 13.3 0.2 8.7 6.0 0.0 2.3 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain CBS PF00571.28 AAG03639.1 - 3.2e-24 85.1 0.7 1.4e-11 44.6 0.1 2.1 2 0 0 2 2 2 2 CBS domain SUFU PF05076.13 AAG03640.1 - 2.8e-22 79.5 0.0 3.4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) MarR PF01047.22 AAG03642.1 - 7.3e-11 41.8 0.0 1.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAG03642.1 - 1.8e-10 40.5 0.2 5.3e-10 39.0 0.2 1.8 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAG03642.1 - 5.5e-05 23.6 0.0 9.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TetR_C_31 PF17940.1 AAG03642.1 - 0.0065 16.7 8.8 0.073 13.3 1.5 2.2 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain AbiEi_4 PF13338.6 AAG03642.1 - 0.048 13.8 0.4 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin UbiD PF01977.16 AAG03643.1 - 1.1e-112 376.9 0.0 1.3e-112 376.6 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF1275 PF06912.11 AAG03644.1 - 2.9e-32 112.2 23.2 3.5e-32 111.9 23.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF543 PF04418.12 AAG03644.1 - 5.8 7.0 10.0 0.2 11.7 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF543) DUF4347 PF14252.6 AAG03645.1 - 2.5e-05 24.2 0.1 5.1e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4347) rve PF00665.26 AAG03646.1 - 6.6e-23 81.2 0.0 1.4e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAG03646.1 - 7.1e-22 77.0 0.1 3e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAG03646.1 - 1e-05 25.8 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 DDE domain rve_2 PF13333.6 AAG03646.1 - 6.1e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain CALCOCO1 PF07888.11 AAG03647.1 - 0.014 14.3 0.6 0.015 14.2 0.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sugarporin_N PF11471.8 AAG03647.1 - 0.054 13.4 0.1 0.067 13.2 0.1 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF2875 PF11394.8 AAG03648.1 - 5.1e-44 150.9 0.0 3e-30 105.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2875) Csa1 PF06023.12 AAG03648.1 - 0.0053 16.1 0.7 0.0098 15.3 0.7 1.3 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 DUF3274 PF11678.8 AAG03649.1 - 3.9e-109 364.3 0.0 5.2e-109 363.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3274) Abhydrolase_1 PF00561.20 AAG03649.1 - 0.0058 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 AAG03649.1 - 0.0099 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 AAG03649.1 - 0.025 13.8 0.0 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 AAG03649.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.25 AAG03649.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1648 PF07853.11 AAG03650.1 - 0.0092 15.6 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1648) Phage_GPD PF05954.11 AAG03651.1 - 1.1e-74 251.5 3.4 1.2e-74 251.4 2.3 1.7 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 AAG03651.1 - 7.8e-48 162.2 7.5 7.8e-48 162.2 7.5 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) T6SS_Vgr PF13296.6 AAG03651.1 - 2.5e-34 117.7 0.5 6e-34 116.4 0.5 1.7 1 0 0 1 1 1 1 Putative type VI secretion system Rhs element Vgr T6SS_HCP PF05638.12 AAG03652.1 - 5.6e-37 127.0 0.1 6.4e-37 126.8 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp Aldedh PF00171.22 AAG03654.1 - 4.2e-173 576.1 0.2 4.7e-173 576.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AAG03654.1 - 0.00095 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) TetR_N PF00440.23 AAG03654.1 - 0.056 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Aminotran_3 PF00202.21 AAG03655.1 - 1.1e-137 459.0 0.1 1.2e-137 458.8 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HDOD PF08668.12 AAG03656.1 - 1.2e-39 135.9 0.0 1.6e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Response_reg PF00072.24 AAG03656.1 - 6.4e-13 48.8 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AAG03656.1 - 0.033 14.4 0.2 0.1 12.9 0.2 1.8 1 0 0 1 1 1 0 HD domain GntR PF00392.21 AAG03657.1 - 7.1e-19 67.2 1.1 1.9e-18 65.8 0.3 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 AAG03657.1 - 2.4e-17 63.2 0.0 3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Fe_dep_repress PF01325.19 AAG03657.1 - 0.0018 18.4 0.0 0.0054 16.9 0.0 1.8 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 AAG03657.1 - 0.002 18.1 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG03657.1 - 0.014 15.3 1.3 0.043 13.7 0.2 2.5 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 AAG03657.1 - 0.019 14.9 0.6 0.072 13.1 0.1 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAG03657.1 - 0.028 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 AAG03657.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAG03657.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AAG03657.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 MarR family CMD PF02627.20 AAG03658.1 - 5.3e-25 87.3 1.2 7.4e-24 83.6 0.8 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Cupin_2 PF07883.11 AAG03659.1 - 2.1e-15 56.2 0.1 3.2e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AAG03659.1 - 0.00072 19.2 0.1 0.00099 18.7 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 AAG03659.1 - 0.002 18.0 0.1 0.0024 17.7 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain AraC_binding PF02311.19 AAG03659.1 - 0.0038 17.1 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AAG03659.1 - 0.069 12.8 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ABM PF03992.16 AAG03660.1 - 2.1e-12 47.0 0.0 3.1e-12 46.4 0.0 1.3 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase LysR_substrate PF03466.20 AAG03661.1 - 3.3e-26 91.9 10.3 4.8e-26 91.4 10.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03661.1 - 5.8e-12 45.4 0.1 2.1e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAG03661.1 - 8.2e-07 28.5 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Mga PF08280.11 AAG03661.1 - 7.8e-06 25.8 0.1 2.4e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_5 PF01022.20 AAG03661.1 - 0.0004 20.2 1.3 0.00048 19.9 0.2 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 AAG03661.1 - 0.00091 19.3 0.0 0.0052 16.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AAG03661.1 - 0.0014 18.4 0.8 0.0049 16.7 0.0 2.4 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAG03661.1 - 0.0014 18.4 0.1 0.0038 17.1 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_30 PF13556.6 AAG03661.1 - 0.0022 17.8 0.1 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain Fe_dep_repress PF01325.19 AAG03661.1 - 0.0039 17.3 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 AAG03661.1 - 0.0046 16.9 0.8 0.0088 16.0 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 AAG03661.1 - 0.0074 16.1 0.0 0.048 13.5 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 AAG03661.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAG03661.1 - 0.017 14.6 0.3 0.047 13.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_8 PF02954.19 AAG03661.1 - 0.041 13.7 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_Crp_2 PF13545.6 AAG03661.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_38 PF13936.6 AAG03661.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAG03661.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 AAG03661.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_IS630 PF01710.16 AAG03661.1 - 0.26 11.3 0.0 0.44 10.6 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_micro PF17007.5 AAG03661.1 - 0.32 9.8 0.0 0.45 9.3 0.0 1.1 1 0 0 1 1 1 0 HTH-like MFS_1 PF07690.16 AAG03662.1 - 3.5e-26 92.0 63.1 5.2e-25 88.1 47.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 AAG03662.1 - 0.0035 16.2 0.8 0.0067 15.3 0.8 1.4 1 0 0 1 1 1 1 POT family MFS_1_like PF12832.7 AAG03662.1 - 0.0085 15.0 0.1 0.023 13.6 0.1 1.7 1 1 0 1 1 1 1 MFS_1 like family cNMP_binding PF00027.29 AAG03664.1 - 1.2e-20 73.4 0.0 3.4e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAG03664.1 - 1.6e-17 63.2 3.2 3.5e-17 62.1 3.2 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAG03664.1 - 8.7e-05 22.0 0.3 0.00022 20.7 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAG03664.1 - 0.00017 21.4 4.1 0.0069 16.3 4.1 2.5 1 1 0 1 1 1 1 MarR family MarR PF01047.22 AAG03664.1 - 0.1 12.5 0.3 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 MarR family HTH_11 PF08279.12 AAG03664.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 HTH domain DUF962 PF06127.11 AAG03665.1 - 6.5e-28 96.7 0.0 1.5e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF4956 PF16316.5 AAG03665.1 - 0.64 9.7 3.9 0.42 10.3 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4956) FA_desaturase PF00487.24 AAG03665.1 - 7.4 6.3 16.6 21 4.8 16.4 1.7 1 1 0 1 1 1 0 Fatty acid desaturase Amastin PF07344.11 AAG03665.1 - 8.5 6.2 8.3 21 4.9 8.3 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein Peptidase_M48 PF01435.18 AAG03666.1 - 1.9e-25 89.8 0.1 2.7e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF3349 PF11829.8 AAG03666.1 - 0.042 14.6 0.1 0.21 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Peptidase_M57 PF12388.8 AAG03666.1 - 0.084 12.5 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase TauE PF01925.19 AAG03667.1 - 3e-25 89.2 40.1 3.8e-25 88.9 40.1 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE HTH_20 PF12840.7 AAG03668.1 - 7.9e-08 32.3 0.7 3.5e-07 30.2 0.4 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AAG03668.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAG03668.1 - 0.00012 21.9 3.2 0.0011 18.9 0.1 3.2 4 0 0 4 4 4 1 MarR family HTH_IclR PF09339.10 AAG03668.1 - 0.0015 18.3 0.9 0.0038 17.0 0.1 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain SelB-wing_2 PF09106.11 AAG03668.1 - 0.0053 16.9 0.4 4.5 7.6 0.0 2.8 2 1 0 2 2 2 2 Elongation factor SelB, winged helix HTH_29 PF13551.6 AAG03668.1 - 0.021 14.9 1.0 0.05 13.6 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix PaaX PF07848.12 AAG03668.1 - 0.022 15.0 0.9 0.75 10.1 0.1 3.0 3 0 0 3 3 3 0 PaaX-like protein HTH_Crp_2 PF13545.6 AAG03668.1 - 0.06 13.3 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HemN_C PF06969.16 AAG03668.1 - 0.066 13.3 0.6 21 5.3 0.0 3.3 3 1 0 3 3 3 0 HemN C-terminal domain HTH_24 PF13412.6 AAG03668.1 - 0.089 12.4 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAG03668.1 - 0.1 12.7 1.8 0.32 11.2 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain ABC_tran PF00005.27 AAG03669.1 - 8.4e-38 130.0 0.0 1.3e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_3 PF12857.7 AAG03669.1 - 3.1e-12 46.2 0.2 1.1e-11 44.4 0.1 2.0 1 1 1 2 2 2 1 TOBE-like domain AAA_21 PF13304.6 AAG03669.1 - 3.4e-09 37.0 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG03669.1 - 2.8e-07 30.2 0.0 1.3e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG03669.1 - 5.2e-05 23.8 0.0 8.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAG03669.1 - 0.00013 22.4 0.0 0.001 19.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TOBE_2 PF08402.10 AAG03669.1 - 0.00016 21.8 0.1 0.00058 20.0 0.1 2.0 1 0 0 1 1 1 1 TOBE domain AAA_16 PF13191.6 AAG03669.1 - 0.00024 21.5 0.3 0.00092 19.6 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAG03669.1 - 0.0012 18.8 0.0 0.0061 16.5 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 AAG03669.1 - 0.0015 18.4 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 AAG03669.1 - 0.0029 17.4 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain TOBE PF03459.17 AAG03669.1 - 0.0031 17.8 0.1 0.01 16.1 0.1 1.9 2 0 0 2 2 2 1 TOBE domain NACHT PF05729.12 AAG03669.1 - 0.0041 17.1 0.3 0.027 14.4 0.1 2.2 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 AAG03669.1 - 0.0069 15.8 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 2 KaiC AAA_29 PF13555.6 AAG03669.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 AAG03669.1 - 0.015 15.0 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAG03669.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG03669.1 - 0.018 15.3 0.1 0.15 12.4 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 AAG03669.1 - 0.021 14.4 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAG03669.1 - 0.026 14.4 0.0 0.063 13.2 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AAG03669.1 - 0.031 14.6 0.6 0.11 12.8 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAG03669.1 - 0.035 14.1 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAG03669.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAG03669.1 - 0.048 13.7 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAG03669.1 - 0.065 13.8 0.0 0.18 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 AAG03669.1 - 0.093 12.2 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 AAG03669.1 - 0.099 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAG03669.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 AAG03669.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 AAG03669.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation BPD_transp_1 PF00528.22 AAG03670.1 - 1.9e-17 63.6 7.4 1.9e-17 63.6 7.4 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2273 PF10031.9 AAG03670.1 - 0.12 12.4 0.0 0.12 12.4 0.0 3.4 5 0 0 5 5 5 0 Small integral membrane protein (DUF2273) Keratin_assoc PF09775.9 AAG03670.1 - 0.63 9.7 9.4 0.52 10.0 0.1 2.7 3 0 0 3 3 3 0 Keratinocyte-associated protein 2 BPD_transp_1 PF00528.22 AAG03671.1 - 2.6e-25 89.2 15.3 2.6e-25 89.2 15.3 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component AIRS PF00586.24 AAG03671.1 - 0.081 13.6 0.3 0.68 10.6 0.1 2.4 1 1 1 2 2 2 0 AIR synthase related protein, N-terminal domain SBP_bac_11 PF13531.6 AAG03672.1 - 8.2e-45 153.3 0.5 1e-44 153.0 0.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03672.1 - 1e-14 55.2 6.7 1e-14 55.2 6.7 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03672.1 - 2.7e-07 30.3 0.4 4.1e-07 29.7 0.4 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAG03672.1 - 0.0017 17.6 0.0 0.0035 16.5 0.0 1.6 1 0 0 1 1 1 1 PBP superfamily domain DUF2292 PF10055.9 AAG03673.1 - 1e-17 63.4 1.1 1.3e-17 63.1 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2292) RACo_linker PF17650.1 AAG03673.1 - 0.072 12.9 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 RACo linker region EAL PF00563.20 AAG03674.1 - 3.3e-76 256.0 0.0 6.6e-76 255.0 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG03674.1 - 1.6e-46 158.0 0.2 5.4e-46 156.3 0.1 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAG03674.1 - 4.6e-35 119.8 1.0 1.5e-21 76.5 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAG03674.1 - 3.2e-25 88.3 0.0 1.4e-15 57.3 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAG03674.1 - 4.8e-19 68.5 0.0 2.7e-15 56.5 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAG03674.1 - 2.1e-14 53.7 5.6 2.2e-09 37.5 0.1 4.1 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 AAG03674.1 - 1.2e-12 47.5 0.1 3.2e-08 33.4 0.0 3.7 3 0 0 3 3 3 2 PAS domain DPM3 PF08285.11 AAG03674.1 - 0.0068 16.6 0.5 0.018 15.2 0.2 1.8 2 0 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) 7tm_7 PF08395.12 AAG03674.1 - 0.09 12.0 0.1 0.2 10.8 0.1 1.5 1 0 0 1 1 1 0 7tm Chemosensory receptor FA_desaturase PF00487.24 AAG03675.1 - 9e-13 48.6 20.1 1.2e-12 48.3 18.6 1.9 1 1 1 2 2 2 1 Fatty acid desaturase DDE_Tnp_ISL3 PF01610.17 AAG03675.1 - 9.2e-10 38.6 4.0 2.1e-09 37.4 4.0 1.6 1 0 0 1 1 1 1 Transposase NapE PF06796.11 AAG03675.1 - 1.4 8.5 5.7 3.4 7.3 5.7 1.7 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE SSF PF00474.17 AAG03676.1 - 1.3e-34 119.7 33.2 2e-34 119.2 33.2 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Arginase PF00491.21 AAG03677.1 - 2.2e-86 289.8 0.0 2.8e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 AAG03677.1 - 0.18 12.0 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 UPF0489 domain LysR_substrate PF03466.20 AAG03678.1 - 4e-27 95.0 1.7 5.6e-27 94.5 1.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03678.1 - 1.8e-14 53.4 0.9 4e-14 52.3 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family ESSS PF10183.9 AAG03678.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GGDEF PF00990.21 AAG03679.1 - 1.9e-44 151.2 0.1 3e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAG03679.1 - 1.8e-18 66.6 0.0 3.5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG03679.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAG03679.1 - 0.00021 21.3 0.0 0.00073 19.5 0.0 2.0 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAG03679.1 - 0.00036 20.5 0.5 0.0061 16.6 0.0 2.8 2 1 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AAG03679.1 - 0.00067 19.9 0.3 0.0053 17.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold GGDEF_2 PF17853.1 AAG03679.1 - 0.0049 17.1 0.1 0.015 15.5 0.1 2.0 2 0 0 2 2 2 1 GGDEF-like domain OprD PF03573.13 AAG03680.1 - 7.2e-154 512.6 8.2 8.3e-154 512.4 8.2 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family PAD_porph PF04371.15 AAG03681.1 - 1.5e-129 431.9 0.0 1.7e-129 431.7 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 AAG03681.1 - 0.01 14.9 0.0 0.23 10.5 0.0 2.4 3 0 0 3 3 3 0 Amidinotransferase CN_hydrolase PF00795.22 AAG03682.1 - 4.2e-53 180.3 0.0 4.8e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TetR_N PF00440.23 AAG03683.1 - 3.4e-09 36.4 0.1 1.2e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_22 PF17928.1 AAG03683.1 - 1.5e-06 28.5 1.0 2.4e-06 27.8 1.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 AAG03683.1 - 0.0074 17.0 4.9 0.0074 17.0 4.9 1.9 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain SBP_bac_8 PF13416.6 AAG03684.1 - 2.2e-27 96.6 0.0 2.6e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03684.1 - 5.4e-24 84.9 0.0 7.2e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03684.1 - 1.2e-12 48.4 0.0 2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG03684.1 - 3.9e-09 36.6 0.4 9.8e-09 35.3 0.4 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAG03684.1 - 3.6e-05 22.7 0.0 0.00046 19.1 0.0 1.9 2 0 0 2 2 2 1 Hypothetical lipoprotein (MG045 family) DDE_Tnp_1_assoc PF13808.6 AAG03684.1 - 0.04 14.0 0.0 5.7 7.0 0.0 3.4 3 1 0 3 3 3 0 DDE_Tnp_1-associated DUF535 PF04393.13 AAG03684.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Gln-synt_C PF00120.24 AAG03685.1 - 1.6e-109 366.0 0.0 1.9e-109 365.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 AAG03685.1 - 0.00013 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 AAG03685.1 - 0.00035 20.2 0.0 0.0098 15.6 0.0 2.5 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF1192 PF06698.11 AAG03685.1 - 0.077 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) RRM_3 PF08777.11 AAG03685.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Peptidase_C26 PF07722.13 AAG03686.1 - 6.2e-77 258.2 0.0 7.1e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 AAG03686.1 - 1.2e-12 48.0 0.0 2.2e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Gln-synt_C PF00120.24 AAG03687.1 - 3.4e-111 371.6 0.0 4e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAG03687.1 - 0.098 12.4 0.4 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Aminotran_3 PF00202.21 AAG03688.1 - 2.6e-94 316.2 0.0 3.1e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SBP_bac_8 PF13416.6 AAG03689.1 - 2.4e-33 116.2 2.6 3e-33 115.8 2.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03689.1 - 2.5e-22 79.5 0.7 3.7e-22 78.9 0.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03689.1 - 4.5e-19 69.5 7.4 6.9e-19 68.9 7.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG03689.1 - 4.7e-09 36.3 0.0 1.2e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAG03689.1 - 3.6e-08 32.6 0.3 3.3e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Hypothetical lipoprotein (MG045 family) SBP_bac_8 PF13416.6 AAG03690.1 - 2.3e-35 122.8 3.0 2.7e-35 122.6 3.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03690.1 - 1e-25 90.6 1.0 1.5e-25 90.0 1.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03690.1 - 1.4e-13 51.5 8.4 1.9e-13 51.1 8.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG03690.1 - 8.6e-08 32.2 0.0 2.6e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAG03690.1 - 0.00035 19.4 0.1 0.08 11.7 0.0 2.1 2 0 0 2 2 2 2 Hypothetical lipoprotein (MG045 family) ABC_tran PF00005.27 AAG03691.1 - 6.3e-38 130.4 0.0 1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAG03691.1 - 6.4e-17 61.5 0.0 1.5e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AAG03691.1 - 2.3e-07 30.9 0.1 0.0033 17.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG03691.1 - 0.00012 21.6 0.4 0.0035 16.8 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG03691.1 - 0.001 18.7 0.2 0.0021 17.8 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG03691.1 - 0.0044 16.9 0.2 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AAG03691.1 - 0.0092 16.4 0.1 0.017 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Pox_A32 PF04665.12 AAG03691.1 - 0.013 15.0 0.4 3.1 7.2 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_28 PF13521.6 AAG03691.1 - 0.017 15.4 0.1 0.096 12.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAG03691.1 - 0.042 14.0 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAG03691.1 - 0.044 13.5 0.2 0.14 11.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG03691.1 - 0.062 13.6 0.4 0.2 11.9 0.4 1.9 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAG03691.1 - 0.09 11.6 0.4 0.89 8.3 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class G-alpha PF00503.20 AAG03691.1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 AAG03691.1 - 0.24 11.9 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAG03692.1 - 4.9e-14 52.5 27.5 5.9e-12 45.7 27.5 2.2 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF3382 PF11862.8 AAG03692.1 - 1.6 9.1 6.4 7.3 6.9 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) BPD_transp_1 PF00528.22 AAG03693.1 - 1.1e-15 57.9 11.9 1.1e-15 57.9 11.9 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component YbhQ PF11076.8 AAG03693.1 - 6.7 6.7 8.1 3 7.9 0.1 2.8 3 1 0 3 3 3 0 Putative inner membrane protein YbhQ Penicil_amidase PF01804.18 AAG03694.1 - 3.2e-202 674.2 12.3 3.7e-202 673.9 12.3 1.0 1 0 0 1 1 1 1 Penicillin amidase DUF4148 PF13663.6 AAG03694.1 - 0.063 13.5 0.9 0.18 12.0 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Arabinose_bd PF12625.7 AAG03695.1 - 1.5e-39 136.0 4.7 3.1e-39 135.0 4.7 1.5 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG03695.1 - 1.9e-15 56.9 1.8 1.9e-15 56.9 1.8 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 AAG03695.1 - 0.025 14.6 0.2 19 5.4 0.0 3.2 2 1 1 3 3 3 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 AAG03695.1 - 0.14 12.3 5.0 10 6.4 0.7 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_AraC PF00165.23 AAG03695.1 - 0.14 12.3 0.0 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAG03695.1 - 0.94 9.4 4.1 1.7 8.5 1.2 2.9 3 1 0 3 3 3 0 Homeodomain-like domain Hydrolase_4 PF12146.8 AAG03697.1 - 2.1e-30 105.8 0.0 2.6e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAG03697.1 - 1e-09 39.3 7.6 1e-09 39.3 7.6 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG03697.1 - 6.6e-06 26.0 1.0 0.0017 18.1 0.7 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2059 PF09832.9 AAG03698.1 - 1.7e-09 37.6 0.2 0.0018 18.3 0.0 2.9 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2059) 2OG-FeII_Oxy_3 PF13640.6 AAG03699.1 - 2.1e-19 70.2 0.0 3.5e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 AAG03699.1 - 1.2e-16 61.1 0.0 2.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 AAG03699.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF523 PF04463.12 AAG03701.1 - 8.6e-40 136.0 0.0 9.9e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF523) BPD_transp_1 PF00528.22 AAG03702.1 - 2e-17 63.5 12.4 2e-17 63.5 12.4 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 AAG03703.1 - 2.6e-60 203.6 0.0 3e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG03703.1 - 1.2e-07 31.9 0.0 2.1e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 AAG03703.1 - 0.0035 17.0 0.0 0.028 14.0 0.0 2.2 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF4399 PF14347.6 AAG03704.1 - 1.1e-39 134.6 1.0 1.4e-39 134.3 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4399) PEGA PF08308.11 AAG03704.1 - 0.1 12.5 0.8 0.76 9.7 0.1 2.5 2 1 1 3 3 3 0 PEGA domain 2-Hacid_dh_C PF02826.19 AAG03705.1 - 1.3e-47 161.5 0.0 2e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAG03705.1 - 9.5e-38 128.9 0.0 1.3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 AAG03705.1 - 0.00029 20.5 0.1 0.00097 18.9 0.1 1.9 1 1 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 AAG03705.1 - 0.0089 16.2 0.3 0.034 14.3 0.1 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 AAG03705.1 - 0.039 13.5 0.4 0.09 12.3 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Tox-PLDMTX PF15645.6 AAG03705.1 - 0.2 11.9 0.0 0.72 10.1 0.0 1.9 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold FAD-oxidase_C PF02913.19 AAG03706.1 - 5.7e-66 222.7 0.0 8.9e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAG03706.1 - 1.5e-37 128.5 0.7 2.4e-37 127.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAA_hydrolase PF01557.18 AAG03707.1 - 1.3e-53 181.9 0.0 1.5e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SdiA-regulated PF06977.11 AAG03708.1 - 7.9e-92 307.0 0.0 9.4e-92 306.7 0.0 1.0 1 0 0 1 1 1 1 SdiA-regulated Phytase-like PF13449.6 AAG03708.1 - 8.6e-09 35.7 0.0 1.4e-06 28.5 0.0 2.6 2 1 1 3 3 3 2 Esterase-like activity of phytase NHL PF01436.21 AAG03708.1 - 3.3e-07 30.0 0.0 3.7e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 NHL repeat BOF PF04076.13 AAG03709.1 - 1.1e-35 121.8 0.2 1.2e-35 121.6 0.2 1.0 1 0 0 1 1 1 1 Bacterial OB fold (BOF) protein Hist_deacetyl PF00850.19 AAG03710.1 - 1.8e-61 208.3 0.0 2.2e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain AA_permease PF00324.21 AAG03711.1 - 2.2e-35 122.2 43.1 2.9e-35 121.8 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG03711.1 - 1.2e-34 119.9 45.5 1.6e-34 119.5 45.5 1.1 1 0 0 1 1 1 1 Amino acid permease SBP_bac_8 PF13416.6 AAG03712.1 - 5.4e-29 101.9 0.1 6.4e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03712.1 - 6.3e-19 68.3 0.0 8.7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03712.1 - 2.5e-14 53.9 0.3 4.6e-14 53.1 0.3 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG03712.1 - 5.6e-09 36.1 0.0 0.0014 18.4 0.0 2.3 2 1 0 2 2 2 2 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 AAG03713.1 - 3.1e-16 59.6 20.3 3.1e-16 59.6 20.3 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG03714.1 - 2.1e-18 66.7 15.3 2.1e-18 66.7 15.3 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2721 PF11026.8 AAG03714.1 - 8.7 6.2 10.3 3.1 7.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) ABC_tran PF00005.27 AAG03715.1 - 2.4e-33 115.5 0.0 4.9e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAG03715.1 - 1.7e-16 60.1 1.0 6.2e-16 58.3 0.3 2.2 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AAG03715.1 - 1.1e-08 35.2 0.1 0.0011 18.9 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG03715.1 - 1e-05 25.1 0.1 0.0017 17.9 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG03715.1 - 5.1e-05 23.6 0.9 0.00043 20.6 0.9 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAG03715.1 - 0.0008 19.8 0.5 0.067 13.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG03715.1 - 0.0054 17.1 0.3 0.014 15.7 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain sCache_3_2 PF17203.4 AAG03715.1 - 0.0077 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Single cache domain 3 RsgA_GTPase PF03193.16 AAG03715.1 - 0.0077 16.1 0.0 0.02 14.8 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 AAG03715.1 - 0.013 16.0 0.4 0.021 15.3 0.1 1.4 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 AAG03715.1 - 0.014 15.0 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAG03715.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 AAG03715.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 AAG03715.1 - 0.032 13.7 0.1 0.8 9.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 AAG03715.1 - 0.043 14.1 0.4 0.39 11.0 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_15 PF13175.6 AAG03715.1 - 0.052 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 AAG03715.1 - 0.09 12.5 0.1 4.4 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAG03715.1 - 0.091 12.8 0.1 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AAG03715.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AAG03715.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain ABC_ATPase PF09818.9 AAG03715.1 - 0.17 10.6 0.5 0.41 9.4 0.1 1.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class SdiA-regulated PF06977.11 AAG03716.1 - 8.6e-107 356.0 0.0 1e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 SdiA-regulated Phytase-like PF13449.6 AAG03716.1 - 1e-10 42.1 0.4 5.2e-07 29.9 0.1 2.8 2 1 0 2 2 2 2 Esterase-like activity of phytase Autotransporter PF03797.19 AAG03717.1 - 2.7e-41 141.9 7.9 2.7e-41 141.9 7.9 1.8 2 0 0 2 2 2 1 Autotransporter beta-domain Peptidase_M28 PF04389.17 AAG03717.1 - 6.7e-28 97.7 0.0 1e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 AAG03717.1 - 0.043 13.5 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 AAG03717.1 - 0.062 12.3 0.0 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase DUF1508 PF07411.12 AAG03718.1 - 4.7e-39 132.0 1.2 2.1e-18 65.9 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1508) DIPSY PF11763.8 AAG03718.1 - 0.0083 16.3 0.3 3.6 7.8 0.0 2.2 1 1 1 2 2 2 2 Cell-wall adhesin ligand-binding C-terminal DUF5633 PF18656.1 AAG03718.1 - 0.029 14.2 0.2 6.7 6.7 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5633) Rib_5-P_isom_A PF06026.14 AAG03719.1 - 6.5e-58 195.1 0.0 8.2e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AAG03719.1 - 0.0094 15.9 0.6 0.039 13.9 0.0 2.2 3 0 0 3 3 3 1 DeoR C terminal sensor domain MGS PF02142.22 AAG03719.1 - 0.033 14.4 0.0 0.081 13.1 0.0 1.7 1 1 0 1 1 1 0 MGS-like domain Sugar-bind PF04198.13 AAG03719.1 - 0.038 13.1 0.0 0.081 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative sugar-binding domain PALP PF00291.25 AAG03720.1 - 3.1e-85 286.2 5.0 4.1e-85 285.7 5.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 AAG03720.1 - 8.7e-50 166.4 0.0 2.5e-25 88.0 0.0 2.6 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase DUF3335 PF11814.8 AAG03720.1 - 0.0061 16.0 0.2 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase_C39 like family DUF2269 PF10027.9 AAG03721.1 - 1.7e-44 151.5 12.2 1.9e-44 151.4 12.2 1.0 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) FixQ PF05545.11 AAG03721.1 - 0.0014 18.6 3.5 0.62 10.1 0.3 2.6 2 0 0 2 2 2 2 Cbb3-type cytochrome oxidase component FixQ YrhK PF14145.6 AAG03721.1 - 1 9.3 8.8 0.36 10.7 1.9 2.6 3 0 0 3 3 3 0 YrhK-like protein DUF2189 PF09955.9 AAG03721.1 - 6.2 7.1 13.8 80 3.5 13.8 2.1 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) DoxX_3 PF13781.6 AAG03722.1 - 1.5e-23 83.4 12.6 1.5e-23 83.4 12.6 2.3 2 0 0 2 2 2 1 DoxX-like family Epimerase PF01370.21 AAG03722.1 - 6.9e-10 38.8 0.0 3.5e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAG03722.1 - 1.1e-07 32.0 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAG03722.1 - 0.00021 20.5 0.0 0.00043 19.5 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAG03722.1 - 0.0059 15.8 0.0 3.6 6.7 0.0 3.0 2 1 1 3 3 3 2 Male sterility protein MFS_1 PF07690.16 AAG03723.1 - 2.8e-23 82.4 59.4 5.3e-16 58.5 32.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 AAG03723.1 - 0.00014 21.0 1.3 0.00025 20.2 1.3 1.3 1 0 0 1 1 1 1 Nucleoside H+ symporter HAD PF12710.7 AAG03724.1 - 6.4e-40 137.6 0.5 7.6e-40 137.3 0.5 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG03724.1 - 0.0034 17.7 0.1 0.0095 16.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAG03724.1 - 0.077 12.7 0.0 2.1 8.0 0.0 2.5 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase NUDIX PF00293.28 AAG03725.1 - 7.9e-26 90.6 0.4 9.6e-26 90.4 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AAG03725.1 - 0.11 12.5 0.2 0.14 12.1 0.2 1.4 1 1 0 1 1 1 0 NUDIX domain NUDIX_2 PF13869.6 AAG03725.1 - 0.16 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase PEP-utilizers_C PF02896.18 AAG03726.1 - 1.2e-98 329.9 0.0 1.9e-98 329.2 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 AAG03726.1 - 1e-27 96.6 0.1 2.9e-27 95.1 0.1 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AAG03726.1 - 1.2e-16 60.1 0.2 3.3e-16 58.8 0.2 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain GAF PF01590.26 AAG03726.1 - 5.3e-16 59.5 0.0 3.5e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 AAG03726.1 - 3.7e-15 56.4 0.1 1.5e-14 54.4 0.1 2.1 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AAG03726.1 - 3.5e-13 50.0 0.1 7.9e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 GAF domain Sec8_exocyst PF04048.14 AAG03726.1 - 0.014 15.3 0.1 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain GGDEF PF00990.21 AAG03727.1 - 1.9e-44 151.3 0.0 3.2e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAG03727.1 - 2.5e-24 85.4 0.1 6e-24 84.2 0.1 1.7 1 0 0 1 1 1 1 PAS fold GGDEF_2 PF17853.1 AAG03727.1 - 0.001 19.3 0.1 0.0027 17.9 0.1 1.7 1 0 0 1 1 1 1 GGDEF-like domain PAS_11 PF14598.6 AAG03727.1 - 0.091 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS domain TANGO2 PF05742.12 AAG03728.1 - 8.4e-57 193.1 0.0 9.5e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 TauE PF01925.19 AAG03729.1 - 6.3e-57 192.9 38.0 7.2e-57 192.7 38.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF5444 PF17519.2 AAG03729.1 - 0.22 11.6 0.3 0.46 10.5 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5444) LGT PF01790.18 AAG03730.1 - 1.8e-84 282.8 8.8 2e-84 282.6 8.8 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase Peptidase_A8 PF01252.18 AAG03730.1 - 0.26 11.5 6.2 1.3 9.3 0.1 3.6 1 1 2 4 4 4 0 Signal peptidase (SPase) II Thymidylat_synt PF00303.19 AAG03731.1 - 6.7e-126 418.9 0.0 7.5e-126 418.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Methyltransf_21 PF05050.12 AAG03732.1 - 6.8e-19 68.5 0.0 9e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Sugarporin_N PF11471.8 AAG03732.1 - 1.2 9.1 4.1 2.2 8.3 4.1 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF3482 PF11981.8 AAG03733.1 - 1.6e-109 365.8 13.4 2.2e-109 365.4 13.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3482) MMR_HSR1 PF01926.23 AAG03733.1 - 5.1e-16 58.8 0.0 9.6e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAG03733.1 - 0.0041 16.6 0.0 0.0086 15.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AAG03733.1 - 0.021 14.7 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 AAG03733.1 - 0.031 13.8 0.0 0.65 9.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AAG03733.1 - 0.033 14.2 0.0 0.57 10.2 0.0 2.3 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 AAG03733.1 - 0.047 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 AAG03733.1 - 0.056 13.0 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Ras family AAA_22 PF13401.6 AAG03733.1 - 0.12 12.6 0.4 0.38 11.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain E2R135 PF11570.8 AAG03733.1 - 0.13 12.6 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Roc PF08477.13 AAG03733.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 AAG03733.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DUF2868 PF11067.8 AAG03734.1 - 1.8e-92 310.2 19.2 4e-92 309.1 19.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) GDPD PF03009.17 AAG03736.1 - 1.3e-50 172.5 0.0 1.6e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DHFR_1 PF00186.19 AAG03739.1 - 9.2e-55 184.7 0.0 1e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Metallophos_2 PF12850.7 AAG03740.1 - 2.5e-31 109.1 0.0 2.9e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAG03740.1 - 0.0055 17.2 0.8 0.9 10.0 0.0 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Xan_ur_permease PF00860.20 AAG03741.1 - 2.2e-94 316.3 45.0 2.6e-94 316.1 45.0 1.0 1 0 0 1 1 1 1 Permease family ILVD_EDD PF00920.21 AAG03742.1 - 2.3e-219 729.3 0.7 2.7e-219 729.1 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family Methyltrans_SAM PF10672.9 AAG03743.1 - 5.5e-19 68.4 0.0 8.3e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PUA_3 PF17785.1 AAG03743.1 - 3.3e-13 49.2 0.0 8e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 PUA-like domain Cons_hypoth95 PF03602.15 AAG03743.1 - 9.1e-13 48.2 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 AAG03743.1 - 5.5e-11 42.3 0.0 7.9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 AAG03743.1 - 2e-10 40.7 0.0 2.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 AAG03743.1 - 5e-10 39.4 0.0 1.3e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAG03743.1 - 3.1e-09 36.6 0.0 6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAG03743.1 - 1e-06 29.4 0.8 6.4e-06 26.8 0.2 2.5 2 1 1 3 3 3 1 Methyltransferase domain UPF0020 PF01170.18 AAG03743.1 - 8.1e-06 25.7 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 AAG03743.1 - 8.9e-05 22.0 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 AAG03743.1 - 0.00055 20.5 0.5 0.0047 17.6 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AAG03743.1 - 0.0015 18.2 0.1 0.01 15.5 0.0 2.2 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F TRM PF02005.16 AAG03743.1 - 0.0026 17.0 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase FtsJ PF01728.19 AAG03743.1 - 0.0071 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spermine_synth PF01564.17 AAG03743.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Spermine/spermidine synthase domain ADH_zinc_N PF00107.26 AAG03743.1 - 0.12 12.4 0.3 0.57 10.2 0.3 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DJ-1_PfpI PF01965.24 AAG03744.1 - 4.1e-45 153.5 0.0 4.6e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AAG03744.1 - 0.00011 22.0 0.0 0.0025 17.5 0.0 2.2 1 1 1 2 2 2 1 ThiJ/PfpI family-like GATase_5 PF13507.6 AAG03744.1 - 0.067 12.3 0.0 0.29 10.2 0.0 1.9 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 AAG03744.1 - 0.075 12.9 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family GATase_3 PF07685.14 AAG03744.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4479 PF14794.6 AAG03744.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) GATase PF00117.28 AAG03744.1 - 0.14 12.0 0.0 0.33 10.7 0.0 1.6 1 1 1 2 2 2 0 Glutamine amidotransferase class-I HDOD PF08668.12 AAG03745.1 - 8.3e-55 185.3 0.0 1e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AAG03745.1 - 0.00048 20.3 0.2 0.0016 18.6 0.2 1.8 1 1 0 1 1 1 1 HD domain Fapy_DNA_glyco PF01149.24 AAG03746.1 - 4.2e-33 114.4 0.0 7.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 AAG03746.1 - 2.9e-25 88.1 0.0 4.7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 AAG03746.1 - 4.3e-09 36.1 3.8 8.4e-09 35.1 3.8 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS DZR PF12773.7 AAG03746.1 - 0.076 13.0 0.8 0.13 12.4 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon FbpA PF05833.11 AAG03746.1 - 0.25 10.1 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Auto_anti-p27 PF06677.12 AAG03746.1 - 0.92 9.7 3.6 0.41 10.8 1.0 1.7 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Acyltransferase PF01553.21 AAG03747.1 - 3.2e-10 39.7 0.0 4.2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Sel1 PF08238.12 AAG03749.1 - 9.9e-28 96.0 38.7 9.8e-10 38.8 0.2 7.0 6 1 0 6 6 6 5 Sel1 repeat G_glu_transpept PF01019.21 AAG03750.1 - 1.1e-158 529.2 0.0 1.3e-158 529.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Fer4 PF00037.27 AAG03751.1 - 1.4e-08 34.1 21.2 3.5e-06 26.6 4.7 3.1 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_7 PF12838.7 AAG03751.1 - 4.3e-06 27.2 15.2 4.1e-05 24.1 15.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG03751.1 - 3.5e-05 24.6 12.4 0.007 17.3 5.3 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AAG03751.1 - 5.2e-05 23.1 13.7 0.0047 16.9 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAG03751.1 - 8.1e-05 22.7 13.5 0.00018 21.6 13.7 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG03751.1 - 0.00011 22.2 23.8 0.0027 17.8 13.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain GF_recep_IV PF14843.6 AAG03751.1 - 0.0038 17.0 7.6 0.0043 16.8 7.6 1.2 1 0 0 1 1 1 1 Growth factor receptor domain IV Fer4_4 PF12800.7 AAG03751.1 - 0.015 15.7 2.8 0.015 15.7 2.8 2.8 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAG03751.1 - 0.035 14.2 20.4 0.18 11.9 5.9 2.5 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 AAG03751.1 - 0.038 14.1 20.0 0.33 11.1 20.2 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG03751.1 - 0.071 13.7 4.1 0.071 13.7 4.1 2.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAG03751.1 - 0.078 14.0 20.8 1.3 10.1 5.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AAG03751.1 - 0.8 10.2 15.6 0.28 11.6 3.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain CTP_transf_like PF01467.26 AAG03752.1 - 7.2e-24 84.6 0.0 8.4e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AAG03752.1 - 1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Citrate lyase ligase C-terminal domain ATP-sulfurylase PF01747.17 AAG03752.1 - 0.0019 17.7 0.0 0.72 9.3 0.0 2.1 1 1 0 2 2 2 2 ATP-sulfurylase GMC_oxred_N PF00732.19 AAG03753.1 - 1.1e-49 169.4 0.0 1.8e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AAG03753.1 - 3.9e-22 79.3 0.0 9.3e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 AAG03753.1 - 3.5e-08 32.9 0.2 0.0036 16.4 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 AAG03753.1 - 0.0015 17.9 0.2 0.0026 17.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 AAG03753.1 - 0.002 17.4 0.1 0.0034 16.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG03753.1 - 0.0029 17.8 0.7 0.0074 16.5 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAG03753.1 - 0.0044 16.3 0.9 0.0078 15.5 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAG03753.1 - 0.039 13.3 4.0 0.48 9.7 3.8 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAG03753.1 - 0.051 12.6 0.2 0.083 11.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 AAG03753.1 - 0.064 12.8 0.4 0.21 11.1 0.2 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG03753.1 - 0.093 11.4 0.6 0.16 10.7 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 AAG03753.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1188 PF06690.11 AAG03753.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TAT_signal PF10518.9 AAG03754.1 - 0.046 13.6 4.3 0.16 11.9 4.3 2.0 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Aldedh PF00171.22 AAG03755.1 - 3.7e-88 296.0 0.0 4.3e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L50 PF10501.9 AAG03755.1 - 0.17 12.1 0.0 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 Ribosomal subunit 39S TetR PF13972.6 AAG03756.1 - 2.3e-46 157.1 0.5 3.1e-46 156.7 0.5 1.2 1 0 0 1 1 1 1 Bacterial transcriptional repressor TetR_N PF00440.23 AAG03756.1 - 1.2e-12 47.4 0.3 3.4e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 AAG03756.1 - 0.016 15.2 0.1 3 8.0 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 AAG03756.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain TetR_C_11 PF16859.5 AAG03756.1 - 0.1 12.9 0.9 0.28 11.5 0.7 1.9 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Abhydrolase_1 PF00561.20 AAG03757.1 - 3.6e-18 66.2 0.1 3.8e-17 62.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG03757.1 - 6.9e-13 49.7 8.5 6.9e-13 49.7 8.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG03757.1 - 6e-12 45.4 0.1 3e-10 39.8 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAG03757.1 - 0.032 14.3 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Chor_lyase PF04345.13 AAG03757.1 - 0.058 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Chorismate lyase Cutinase PF01083.22 AAG03757.1 - 0.069 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase Cons_hypoth95 PF03602.15 AAG03759.1 - 3.9e-59 199.3 0.0 4.4e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AAG03759.1 - 5.3e-05 22.8 0.0 7.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAG03759.1 - 9.2e-05 22.3 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.15 AAG03759.1 - 0.0001 22.1 0.0 0.0063 16.2 0.0 2.0 1 1 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 AAG03759.1 - 0.00022 21.9 0.0 0.00031 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NABP PF07990.12 AAG03759.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP UPF0020 PF01170.18 AAG03759.1 - 0.017 14.8 0.0 0.049 13.3 0.0 1.7 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 AAG03759.1 - 0.028 13.7 0.0 0.062 12.6 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.18 AAG03759.1 - 0.12 12.1 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 DNA methylase Methyltransf_24 PF13578.6 AAG03759.1 - 0.13 13.3 0.0 0.23 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AAG03759.1 - 0.2 11.3 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PrmA PF06325.13 AAG03759.1 - 0.21 10.9 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_M16_C PF05193.21 AAG03760.1 - 3.8e-32 111.8 0.0 9.4e-31 107.2 0.0 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AAG03760.1 - 2.7e-05 24.2 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) T2SSM PF04612.12 AAG03760.1 - 0.0099 15.9 0.4 0.04 14.0 0.3 2.0 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M NblA PF04485.12 AAG03760.1 - 0.084 13.3 0.6 19 5.8 0.0 3.2 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA ADSL_C PF10397.9 AAG03760.1 - 0.16 12.5 0.5 0.71 10.5 0.0 2.3 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Peptidase_M16_C PF05193.21 AAG03761.1 - 1.6e-30 106.5 0.0 3.8e-28 98.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AAG03761.1 - 1.4e-20 73.8 0.0 2.1e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SRP54 PF00448.22 AAG03762.1 - 2.5e-77 258.9 2.9 3.7e-77 258.4 2.9 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AAG03762.1 - 7.1e-14 51.8 0.7 1.8e-13 50.5 0.7 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 AAG03762.1 - 9.8e-07 28.2 0.1 1.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 AAG03762.1 - 3.9e-05 23.5 1.4 7.3e-05 22.6 1.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG03762.1 - 6.5e-05 23.2 0.9 0.0002 21.6 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAG03762.1 - 0.00015 21.9 0.1 0.00032 20.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAG03762.1 - 0.00039 20.8 0.6 0.00065 20.1 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_31 PF13614.6 AAG03762.1 - 0.00066 19.6 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 AAG03762.1 - 0.00076 18.5 0.9 0.0024 16.9 0.4 2.1 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 AAG03762.1 - 0.0012 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 AAG03762.1 - 0.0014 19.0 0.1 0.0027 18.1 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG03762.1 - 0.0018 18.7 0.5 0.0018 18.7 0.5 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 AAG03762.1 - 0.002 18.7 0.3 0.0091 16.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 AAG03762.1 - 0.0026 17.8 0.3 0.0059 16.6 0.3 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 AAG03762.1 - 0.0039 17.3 0.8 0.012 15.7 0.8 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.9 AAG03762.1 - 0.005 16.1 0.2 0.0068 15.7 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 AAG03762.1 - 0.0058 16.7 0.0 0.0096 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAG03762.1 - 0.006 17.1 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 AAG03762.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 AAG03762.1 - 0.0072 16.0 0.5 0.048 13.3 0.3 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_19 PF13245.6 AAG03762.1 - 0.036 14.4 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAG03762.1 - 0.084 12.8 1.7 0.35 10.8 0.7 2.2 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 AAG03762.1 - 0.099 12.2 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 1 0 P-loop containing dynein motor region AIG1 PF04548.16 AAG03762.1 - 0.1 11.9 0.5 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Fer4_NifH PF00142.18 AAG03762.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PIF1 PF05970.14 AAG03762.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.18 AAG03762.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 AAG03762.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_3 PF07726.11 AAG03762.1 - 0.14 12.0 0.3 0.42 10.5 0.1 2.1 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 AAG03762.1 - 0.16 11.7 0.4 0.3 10.8 0.4 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 AAG03762.1 - 0.19 11.6 3.8 0.14 12.0 1.2 2.1 3 0 0 3 3 3 0 NTPase ArsA_ATPase PF02374.15 AAG03762.1 - 0.2 10.8 1.5 0.36 10.0 0.8 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase SPESP1 PF15754.5 AAG03762.1 - 0.7 9.0 8.8 3 6.9 8.8 1.9 1 1 1 2 2 2 0 Sperm equatorial segment protein 1 ABC_tran PF00005.27 AAG03763.1 - 9.1e-35 120.1 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG03763.1 - 6.7e-10 39.3 0.5 9.3e-07 28.9 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG03763.1 - 6.4e-06 26.7 0.1 9.3e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG03763.1 - 9.2e-05 22.1 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG03763.1 - 0.00025 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAG03763.1 - 0.0011 19.2 0.3 0.0028 17.9 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAG03763.1 - 0.019 15.1 0.2 0.056 13.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 AAG03763.1 - 0.021 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 AAG03763.1 - 0.052 13.5 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 AAG03763.1 - 0.06 13.8 0.0 0.094 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAG03763.1 - 0.066 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 AAG03763.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 AAG03763.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 AAG03763.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.9 AAG03763.1 - 0.24 10.6 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsX_ECD PF18075.1 AAG03764.1 - 4e-16 59.4 0.1 6.9e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 FtsX extracellular domain POTRA_1 PF08478.10 AAG03764.1 - 0.022 15.1 0.5 0.19 12.1 0.1 2.3 2 0 0 2 2 2 0 POTRA domain, FtsQ-type AsnC_trans_reg PF01037.21 AAG03764.1 - 0.05 13.6 0.0 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain SPO11_like PF03533.14 AAG03764.1 - 1.6 8.9 4.5 0.26 11.4 0.3 2.0 2 0 0 2 2 2 0 SPO11 homologue Sigma70_r2 PF04542.14 AAG03765.1 - 3.9e-16 58.6 0.0 1.2e-15 57.0 0.0 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG03765.1 - 4.4e-16 58.1 2.3 1.1e-15 56.8 0.4 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AAG03765.1 - 6.8e-06 26.0 0.2 6.8e-06 26.0 0.2 1.8 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 UCR_14kD PF02271.16 AAG03765.1 - 0.0075 16.2 0.6 0.12 12.3 0.0 2.9 2 2 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit HTH_25 PF13413.6 AAG03765.1 - 0.011 15.6 0.4 0.1 12.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain IF2_N PF04760.15 AAG03765.1 - 0.032 14.0 0.4 1.3 8.9 0.1 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Sigma70_r3 PF04539.16 AAG03765.1 - 0.051 13.7 1.4 8 6.6 0.2 2.8 2 0 0 2 2 2 0 Sigma-70 region 3 GntR PF00392.21 AAG03765.1 - 0.43 10.3 0.1 0.43 10.3 0.1 2.6 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family Transgly PF00912.22 AAG03767.1 - 4.6e-46 156.5 0.0 5.9e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase DUF2267 PF10025.9 AAG03767.1 - 0.029 14.6 0.1 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF423 PF04241.15 AAG03768.1 - 8.5e-30 102.8 7.1 1.2e-29 102.3 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) FtsX PF02687.21 AAG03768.1 - 6.4 7.3 11.5 0.065 13.7 1.8 2.2 1 1 1 2 2 2 0 FtsX-like permease family ThiS PF02597.20 AAG03769.1 - 3.7e-17 62.7 0.1 4.2e-17 62.6 0.1 1.0 1 0 0 1 1 1 1 ThiS family Ub-RnfH PF03658.14 AAG03769.1 - 0.055 13.9 0.0 0.059 13.8 0.0 1.2 1 0 0 1 1 1 0 RnfH family Ubiquitin ThiG PF05690.14 AAG03770.1 - 1.9e-113 377.9 1.4 2.1e-113 377.7 1.4 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AAG03770.1 - 0.00034 20.2 0.0 0.0033 16.9 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 AAG03770.1 - 0.012 14.7 1.3 0.024 13.7 0.5 1.7 1 1 0 2 2 2 0 FMN-dependent dehydrogenase Hydrolase PF00702.26 AAG03770.1 - 0.015 15.6 0.1 0.027 14.7 0.0 1.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NanE PF04131.14 AAG03770.1 - 0.09 12.0 1.2 0.52 9.5 0.4 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 AAG03770.1 - 0.14 11.1 1.3 0.26 10.3 0.4 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Methyltransf_4 PF02390.17 AAG03771.1 - 3.4e-55 186.2 0.0 4e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 AAG03771.1 - 0.024 15.3 0.0 0.049 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1329 PF07044.11 AAG03772.1 - 5.8e-138 460.1 0.4 6.7e-138 459.9 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) LolA_like PF17131.4 AAG03772.1 - 4.2e-05 23.4 0.0 7.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Outer membrane lipoprotein-sorting protein DUF3392 PF11872.8 AAG03774.1 - 3.9e-41 139.6 4.7 4.3e-41 139.4 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) EBP PF05241.12 AAG03774.1 - 0.003 17.1 1.9 0.0037 16.7 1.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2206 PF09971.9 AAG03774.1 - 0.072 11.8 4.1 0.085 11.6 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) ABC2_membrane_4 PF12730.7 AAG03774.1 - 1.1 9.2 9.0 1.4 8.8 9.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2070 PF09843.9 AAG03774.1 - 3.1 6.0 6.1 3.8 5.7 6.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Radical_SAM PF04055.21 AAG03775.1 - 3.5e-20 73.1 0.0 5.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AAG03775.1 - 6.5e-14 51.7 0.1 3.5e-13 49.4 0.0 2.3 3 0 0 3 3 3 1 HemN C-terminal domain Fer4_12 PF13353.6 AAG03775.1 - 0.036 14.4 0.0 0.054 13.8 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain Ham1p_like PF01725.16 AAG03776.1 - 6.3e-61 205.6 0.0 7.1e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF4426 PF14467.6 AAG03777.1 - 1.2e-40 138.3 0.0 1.3e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4426) MetW PF07021.12 AAG03778.1 - 8.6e-92 306.0 0.0 9.6e-92 305.9 0.0 1.0 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 AAG03778.1 - 1.4e-13 51.3 0.0 2.8e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG03778.1 - 1.8e-11 44.1 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG03778.1 - 1.8e-11 44.6 0.0 3.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG03778.1 - 3.2e-11 43.3 0.0 5.5e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG03778.1 - 4.6e-09 36.9 0.1 8.4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AAG03778.1 - 0.0014 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG03778.1 - 0.036 13.6 0.0 0.056 13.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 AAG03778.1 - 0.037 13.4 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family HU-CCDC81_euk_2 PF18289.1 AAG03778.1 - 0.052 13.7 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 DREV PF05219.12 AAG03778.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 2 0 0 2 2 2 0 DREV methyltransferase Methyltransf_32 PF13679.6 AAG03778.1 - 0.15 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 AAG03778.1 - 0.18 11.2 0.1 0.24 10.8 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Abhydrolase_1 PF00561.20 AAG03779.1 - 3.8e-32 112.0 0.1 5.5e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 AAG03779.1 - 0.0017 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 AAG03779.1 - 0.02 14.2 0.0 0.053 12.8 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 AAG03779.1 - 0.044 13.6 0.9 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Dynamin_N PF00350.23 AAG03780.1 - 2.3e-13 50.6 0.0 2.5e-12 47.2 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 AAG03780.1 - 0.0014 18.7 0.0 0.011 15.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase YGGT PF02325.17 AAG03781.1 - 1e-38 131.6 25.8 1.4e-20 73.5 3.6 2.5 3 0 0 3 3 3 2 YGGT family HXXEE PF13787.6 AAG03781.1 - 0.19 12.6 8.5 0.75 10.6 8.5 2.0 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif DUF1449 PF07290.11 AAG03781.1 - 5.7 6.5 12.9 1.5 8.4 9.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) P5CR_dimer PF14748.6 AAG03782.1 - 7.3e-38 129.0 4.2 7.3e-38 129.0 4.2 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AAG03782.1 - 2.4e-23 82.5 2.6 2.4e-23 82.5 2.6 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAG03782.1 - 8e-08 32.6 0.1 1.7e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AAG03782.1 - 6.1e-05 23.1 1.3 7.6e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OCD_Mu_crystall PF02423.15 AAG03782.1 - 0.00012 21.1 0.8 0.00025 20.1 0.8 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PDH PF02153.17 AAG03782.1 - 0.00013 21.1 0.1 0.00021 20.4 0.1 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase ApbA PF02558.16 AAG03782.1 - 0.00017 21.3 0.7 0.00039 20.1 0.7 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 AAG03782.1 - 0.00023 21.9 0.5 0.0015 19.4 0.2 2.2 3 0 0 3 3 2 1 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_C PF03720.15 AAG03782.1 - 0.0028 18.1 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Shikimate_DH PF01488.20 AAG03782.1 - 0.0037 17.3 0.3 0.0084 16.2 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 AAG03782.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Crp PF00325.20 AAG03782.1 - 0.1 12.2 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family 3HCDH_RFF PF18321.1 AAG03782.1 - 0.45 11.0 7.7 2.7 8.5 0.3 3.9 3 1 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Ala_racemase_N PF01168.20 AAG03783.1 - 3.1e-34 118.6 0.3 3.7e-34 118.3 0.3 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Bac_luciferase PF00296.20 AAG03783.1 - 0.027 13.9 0.7 0.05 13.0 0.7 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase T2SSE PF00437.20 AAG03784.1 - 1.5e-46 158.7 0.3 1.8e-45 155.1 0.1 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 AAG03784.1 - 6.7e-05 23.3 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAG03784.1 - 7.9e-05 23.0 0.0 0.00018 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG03784.1 - 0.00016 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG03784.1 - 0.00045 20.8 0.0 0.00084 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG03784.1 - 0.0044 16.8 0.2 0.023 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AAG03784.1 - 0.0047 17.3 0.4 0.018 15.4 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AAG03784.1 - 0.0058 16.2 0.1 0.014 14.9 0.1 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_27 PF13514.6 AAG03784.1 - 0.0071 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AAG03784.1 - 0.0076 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 AAG03784.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF87 PF01935.17 AAG03784.1 - 0.0082 16.3 0.1 0.023 14.8 0.1 1.5 1 1 0 1 1 1 1 Helicase HerA, central domain DAP3 PF10236.9 AAG03784.1 - 0.0096 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 AAG03784.1 - 0.0099 15.8 0.3 0.15 11.9 0.1 2.3 1 1 1 2 2 2 1 NTPase ABC_tran PF00005.27 AAG03784.1 - 0.013 16.0 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 AAG03784.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 AAG03784.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 AAG03784.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 AAG03784.1 - 0.039 13.9 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AAG03784.1 - 0.043 13.7 0.0 0.64 9.9 0.0 2.6 3 0 0 3 3 3 0 NACHT domain TrwB_AAD_bind PF10412.9 AAG03784.1 - 0.048 12.6 0.0 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 AAG03784.1 - 0.059 13.8 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 AAG03784.1 - 0.062 13.1 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAG03784.1 - 0.067 13.3 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAG03784.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain KTI12 PF08433.10 AAG03784.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 AAG03784.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAG03784.1 - 0.091 13.3 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAG03784.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 AAG03784.1 - 0.095 12.6 0.1 0.23 11.4 0.1 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain TK PF00265.18 AAG03784.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase DUF2075 PF09848.9 AAG03784.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 AAG03785.1 - 1.3e-35 122.8 0.3 1.8e-35 122.3 0.3 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AAG03785.1 - 0.00043 20.8 0.0 0.0011 19.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 AAG03785.1 - 0.0023 17.5 0.0 0.0053 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 AAG03785.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AAG03785.1 - 0.041 13.9 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 AAG03785.1 - 0.042 13.2 0.1 0.077 12.3 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 AAG03785.1 - 0.047 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 AAG03785.1 - 0.052 13.3 0.5 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG03785.1 - 0.056 13.9 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG03785.1 - 0.097 12.9 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain Cation_efflux PF01545.21 AAG03786.1 - 2.6e-45 154.6 16.3 3.3e-45 154.3 16.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAG03786.1 - 0.011 15.9 0.1 0.024 14.8 0.0 1.6 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter SQS_PSY PF00494.19 AAG03786.1 - 0.018 14.5 0.1 0.034 13.6 0.1 1.4 1 0 0 1 1 1 0 Squalene/phytoene synthase Anoctamin PF04547.12 AAG03786.1 - 1.4 7.7 3.5 0.57 9.0 0.6 1.7 1 1 0 1 1 1 0 Calcium-activated chloride channel TM2 PF05154.16 AAG03787.1 - 3.4e-30 104.1 31.9 5.5e-15 55.4 11.3 2.1 2 0 0 2 2 2 2 TM2 domain DUF5353 PF17304.2 AAG03787.1 - 0.023 14.4 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5353) PALP PF00291.25 AAG03788.1 - 5.2e-65 219.8 0.1 7.4e-65 219.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 AAG03788.1 - 1e-15 57.9 0.8 1.1e-09 38.6 0.3 2.9 3 0 0 3 3 3 2 CBS domain GAF PF01590.26 AAG03788.1 - 0.043 14.4 0.0 0.099 13.3 0.0 1.6 1 0 0 1 1 1 0 GAF domain Cys_Met_Meta_PP PF01053.20 AAG03789.1 - 2.3e-149 497.1 0.0 2.6e-149 496.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AAG03789.1 - 0.00034 19.9 0.0 0.00047 19.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAG03789.1 - 0.00051 19.1 0.0 0.00068 18.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Amidohydro_1 PF01979.20 AAG03790.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG03790.1 - 3.7e-08 33.3 1.4 1.4e-07 31.4 0.0 2.5 3 0 0 3 3 3 1 Amidohydrolase family DHOase PF12890.7 AAG03790.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.5 1 1 0 1 1 1 1 Dihydro-orotase-like OTCace_N PF02729.21 AAG03791.1 - 1.6e-41 141.8 0.1 2.4e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AAG03791.1 - 5.6e-24 85.0 0.0 1.1e-23 84.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pribosyltran PF00156.27 AAG03792.1 - 1e-16 60.9 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAG03792.1 - 0.00029 20.3 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AAG03792.1 - 0.0049 16.4 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase Creatininase PF02633.14 AAG03792.1 - 0.08 12.4 0.0 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 Creatinine amidohydrolase RuvX PF03652.15 AAG03793.1 - 1.3e-39 135.7 0.0 1.5e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase FTCD_N PF07837.12 AAG03793.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain DUF179 PF02622.15 AAG03794.1 - 3e-47 160.5 0.0 3.4e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 TonB_C PF03544.14 AAG03795.1 - 9.7e-17 61.2 0.0 3.5e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAG03795.1 - 2.4e-05 24.5 0.0 5.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 TonB C terminal TFIIA PF03153.13 AAG03795.1 - 0.014 15.4 4.6 0.015 15.3 4.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GSH-S_ATP PF02955.16 AAG03796.1 - 1.7e-79 265.3 0.0 2.3e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 AAG03796.1 - 4.1e-44 149.5 0.0 6e-44 149.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 AAG03796.1 - 3.8e-08 33.2 0.0 5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAG03796.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 AAG03796.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain Response_reg PF00072.24 AAG03797.1 - 3e-25 88.5 0.1 3.5e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain EF-hand_13 PF17958.1 AAG03797.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain DUF713 PF05218.14 AAG03797.1 - 0.071 12.8 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) FleQ PF06490.11 AAG03797.1 - 0.2 12.1 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Response_reg PF00072.24 AAG03798.1 - 3.6e-28 98.0 0.2 4.1e-28 97.8 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 AAG03798.1 - 0.0029 17.6 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain FleQ PF06490.11 AAG03798.1 - 0.026 14.9 0.0 0.029 14.8 0.0 1.1 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ CheW PF01584.19 AAG03799.1 - 5.7e-27 94.0 0.0 7.5e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain MCPsignal PF00015.21 AAG03800.1 - 1.1e-43 149.1 26.3 1.1e-43 149.1 26.3 4.8 3 2 2 5 5 5 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PilJ PF13675.6 AAG03800.1 - 1.7e-25 89.3 27.7 2.3e-25 88.8 0.3 5.3 4 1 1 5 5 5 2 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1772 PF08592.11 AAG03800.1 - 0.048 14.0 0.1 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4917 PF16263.5 AAG03800.1 - 0.17 11.2 1.7 1.3 8.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4917) BLOC1_2 PF10046.9 AAG03800.1 - 0.5 10.7 24.0 0.41 11.0 0.3 6.1 4 2 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2894 PF11445.8 AAG03800.1 - 0.94 9.9 10.7 2.2 8.7 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Tnp_22_trimer PF17489.2 AAG03800.1 - 2.3 8.3 4.9 3.4 7.7 0.4 3.1 3 0 0 3 3 3 0 L1 transposable element trimerization domain AIP3 PF03915.13 AAG03800.1 - 9.2 5.2 25.1 0.57 9.2 6.8 2.7 2 1 1 3 3 3 0 Actin interacting protein 3 CheR PF01739.18 AAG03801.1 - 2.3e-59 200.2 0.0 3.1e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAG03801.1 - 3.7e-11 42.6 0.1 6.1e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 AAG03801.1 - 4.1e-05 24.2 0.0 0.0002 22.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG03801.1 - 8.8e-05 23.1 0.0 0.035 14.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG03801.1 - 0.00044 20.8 0.1 0.0067 17.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG03801.1 - 0.00067 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG03801.1 - 0.0036 17.1 0.0 0.23 11.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Hpt PF01627.23 AAG03802.1 - 1.1e-83 275.6 79.5 3.9e-15 55.9 3.7 10.7 9 1 1 10 10 10 8 Hpt domain Response_reg PF00072.24 AAG03802.1 - 5.1e-28 97.5 0.2 1.6e-27 95.9 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain CheW PF01584.19 AAG03802.1 - 3.1e-23 81.9 0.1 9.7e-23 80.3 0.1 1.9 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.26 AAG03802.1 - 2.3e-16 60.3 0.3 5.9e-16 59.0 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAG03802.1 - 3.1e-05 24.3 7.4 0.00086 19.6 7.4 3.5 1 1 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain FliS PF02561.14 AAG03802.1 - 0.0051 17.1 4.5 2.2 8.6 0.1 4.6 5 0 0 5 5 5 2 Flagellar protein FliS CheB_methylest PF01339.17 AAG03803.1 - 1.2e-39 135.7 0.0 1.7e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 CheB methylesterase CheW PF01584.19 AAG03804.1 - 8e-10 38.5 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain AraC_binding PF02311.19 AAG03805.1 - 1.2e-21 77.0 0.0 2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_18 PF12833.7 AAG03805.1 - 5.9e-21 74.5 1.2 1.1e-20 73.7 1.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG03805.1 - 3.5e-16 58.8 0.0 2e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 AAG03805.1 - 4.9e-05 23.1 9.8 0.002 17.8 9.8 2.3 1 1 0 1 1 1 1 AraC-binding-like domain Phage_integrase PF00589.22 AAG03805.1 - 0.061 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family LysE PF01810.18 AAG03806.1 - 1.3e-51 174.8 9.9 1.7e-51 174.4 9.9 1.1 1 0 0 1 1 1 1 LysE type translocator DUF2842 PF11003.8 AAG03806.1 - 0.6 10.4 0.1 0.6 10.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2842) HisKA_7TM PF16927.5 AAG03806.1 - 2.6 8.0 11.6 0.033 14.2 2.8 2.1 2 1 0 2 2 2 0 N-terminal 7TM region of histidine kinase Luciferase_cat PF10285.9 AAG03807.1 - 0.23 10.8 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain EccE PF11203.8 AAG03807.1 - 0.24 11.7 2.8 0.35 11.2 1.6 1.9 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Spo0M PF07070.11 AAG03807.1 - 0.24 10.9 0.0 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 SpoOM protein Methyltrans_RNA PF04452.14 AAG03808.1 - 5e-71 238.6 0.0 5.7e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase Aminotran_3 PF00202.21 AAG03809.1 - 1.5e-121 405.9 0.0 1.7e-121 405.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Amino_oxidase PF01593.24 AAG03810.1 - 2.3e-48 165.6 0.2 2.3e-47 162.3 0.2 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAG03810.1 - 1.1e-11 44.8 0.1 5.2e-11 42.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAG03810.1 - 5.6e-11 42.6 0.8 4.9e-10 39.5 0.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG03810.1 - 2.2e-08 33.6 0.8 3.9e-08 32.8 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAG03810.1 - 1.2e-06 28.1 0.0 0.0003 20.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG03810.1 - 1.8e-06 26.9 1.5 0.0004 19.2 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 AAG03810.1 - 2.1e-06 27.2 3.7 0.0057 16.0 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG03810.1 - 1.3e-05 24.5 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 AAG03810.1 - 5.6e-05 23.6 0.5 0.00098 19.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAG03810.1 - 0.00011 21.4 0.4 0.0046 16.1 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 AAG03810.1 - 0.00016 21.2 0.6 0.00025 20.5 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAG03810.1 - 0.00029 20.2 0.9 0.00036 19.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 AAG03810.1 - 0.0015 18.5 0.3 1.7 8.6 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 AAG03810.1 - 0.0017 17.5 0.4 0.0017 17.5 0.4 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAG03810.1 - 0.0098 15.2 1.1 0.013 14.8 0.4 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AAG03810.1 - 0.08 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 AAG03810.1 - 0.094 12.4 0.1 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ni_hydr_CYTB PF01292.20 AAG03811.1 - 1.2e-31 109.7 11.6 1.4e-31 109.5 11.6 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AAG03811.1 - 0.0013 19.2 3.0 0.0013 19.2 3.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4405) COX15-CtaA PF02628.15 AAG03811.1 - 0.042 12.9 3.7 0.54 9.3 2.6 2.1 1 1 1 2 2 2 0 Cytochrome oxidase assembly protein DUF2759 PF10958.8 AAG03811.1 - 0.9 9.3 0.1 0.9 9.3 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2759) YceI PF04264.13 AAG03812.1 - 1.7e-41 142.2 0.1 2.1e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 YceI-like domain MarR PF01047.22 AAG03813.1 - 4.9e-17 61.6 0.2 9.8e-17 60.6 0.2 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAG03813.1 - 1.6e-08 34.9 0.1 4.6e-08 33.5 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AAG03813.1 - 2.9e-08 33.5 0.4 5.1e-08 32.7 0.4 1.4 1 0 0 1 1 1 1 MarR family HTH_38 PF13936.6 AAG03813.1 - 0.068 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HxlR PF01638.17 AAG03813.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix TrmB PF01978.19 AAG03813.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HlyD_D23 PF16576.5 AAG03814.1 - 8.6e-17 61.1 1.8 5.2e-16 58.5 1.8 2.0 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG03814.1 - 2.1e-12 46.6 0.4 1.4e-08 34.4 0.2 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AAG03814.1 - 1.8e-09 38.2 6.3 7.4e-06 26.6 0.1 3.3 3 1 0 3 3 3 2 HlyD family secretion protein HlyD PF00529.20 AAG03814.1 - 7e-09 35.5 9.3 1.3e-08 34.6 9.2 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS PTS_EIIA_1 PF00358.20 AAG03814.1 - 0.0079 16.0 0.2 0.74 9.6 0.0 3.0 3 0 0 3 3 3 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ACR_tran PF00873.19 AAG03815.1 - 0 1437.4 11.0 0 1437.2 11.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AAG03815.1 - 2.1e-07 30.5 24.8 0.00067 19.1 3.6 3.0 3 0 0 3 3 3 2 Protein export membrane protein Patched PF02460.18 AAG03815.1 - 5.2 5.0 25.8 0.13 10.3 14.9 2.1 2 0 0 2 2 2 0 Patched family OEP PF02321.18 AAG03816.1 - 4.4e-55 186.4 32.7 8.4e-28 97.5 15.6 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein LPAM_1 PF08139.12 AAG03816.1 - 0.00017 21.9 1.6 0.00064 20.1 1.6 2.1 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site CENP-K PF11802.8 AAG03816.1 - 0.054 13.1 0.3 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Centromere-associated protein K DEAD PF00270.29 AAG03817.1 - 4.8e-46 156.7 0.0 4.1e-45 153.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG03817.1 - 1.4e-26 93.0 0.0 3.1e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAG03817.1 - 3.5e-07 30.4 0.0 8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAG03817.1 - 3.4e-06 27.5 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF5008 PF16400.5 AAG03818.1 - 0.05 13.7 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5008) MTHFR PF02219.17 AAG03819.1 - 2e-88 296.5 0.0 2.3e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase HD_4 PF13328.6 AAG03820.1 - 1.6e-10 40.9 0.0 4.6e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 HD domain AdoHcyase PF05221.17 AAG03821.1 - 8.5e-128 425.7 0.0 5.1e-72 242.5 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AAG03821.1 - 3.5e-57 193.0 2.6 1.6e-56 190.8 2.6 2.0 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 AAG03821.1 - 0.0007 20.0 0.1 0.0016 18.8 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding IlvN PF07991.12 AAG03821.1 - 0.0008 19.0 0.1 0.002 17.7 0.1 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 AAG03821.1 - 0.029 13.7 0.8 0.5 9.7 0.7 2.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAG03821.1 - 0.055 13.7 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF2946 PF11162.8 AAG03822.1 - 2.8e-08 34.4 7.0 3.8e-08 34.0 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) TonB_dep_Rec PF00593.24 AAG03823.1 - 1e-53 183.9 32.8 1e-53 183.9 32.8 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG03823.1 - 3e-19 69.6 0.9 5.5e-19 68.7 0.9 1.5 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain PepSY_TM PF03929.16 AAG03824.1 - 7.3e-16 58.7 12.6 1.2e-10 41.5 6.4 2.4 1 1 0 2 2 2 2 PepSY-associated TM region Cytochrom_B561 PF03188.16 AAG03824.1 - 0.021 14.9 3.9 0.075 13.2 0.4 2.5 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 AAG03824.1 - 7.2 6.2 13.3 0.98 9.0 2.4 2.8 3 1 0 3 3 3 0 Prokaryotic cytochrome b561 TetR_C_3 PF08362.11 AAG03825.1 - 1.7e-54 183.7 0.0 2.8e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 AAG03825.1 - 1.7e-14 53.4 0.1 2.4e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Amidohydro_3 PF07969.11 AAG03826.1 - 6.2e-53 180.9 0.4 1.5e-51 176.3 0.4 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AAG03826.1 - 6.9e-14 51.9 0.0 9e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family TatD_DNase PF01026.21 AAG03826.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase RP-C PF03428.13 AAG03826.1 - 0.089 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain Transp_cyt_pur PF02133.15 AAG03827.1 - 7.7e-60 202.9 43.3 9.6e-60 202.6 43.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DHO_dh PF01180.21 AAG03828.1 - 9.8e-28 97.2 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.6 AAG03828.1 - 1.6e-22 79.4 14.2 3.6e-22 78.3 14.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAG03828.1 - 2e-07 31.5 10.0 2e-07 31.5 10.0 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Dus PF01207.17 AAG03828.1 - 2.8e-07 29.9 0.2 1.2e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Fer4_6 PF12837.7 AAG03828.1 - 4.3e-06 26.6 2.9 4.3e-06 26.6 2.9 3.0 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4 PF00037.27 AAG03828.1 - 1.3e-05 24.8 21.8 0.00029 20.5 4.2 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAG03828.1 - 4.5e-05 23.5 14.2 0.0028 17.7 0.9 2.8 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAG03828.1 - 9.6e-05 23.2 10.6 0.0067 17.3 2.2 2.5 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG03828.1 - 0.0012 19.0 11.6 0.0012 19.0 11.6 2.3 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG03828.1 - 0.0021 18.4 2.9 0.0021 18.4 2.9 3.6 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAG03828.1 - 0.0046 17.0 20.0 0.029 14.5 3.0 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain NMO PF03060.15 AAG03828.1 - 0.0088 15.5 2.0 0.061 12.7 2.0 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase Fer4_17 PF13534.6 AAG03828.1 - 0.026 15.0 11.1 0.6 10.7 1.8 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG03828.1 - 0.027 14.9 14.9 0.032 14.7 11.8 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 AAG03828.1 - 0.1 12.8 0.2 0.1 12.8 0.2 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain NanE PF04131.14 AAG03828.1 - 0.32 10.1 1.7 9.7 5.3 0.1 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Fer4_16 PF13484.6 AAG03828.1 - 2.8 9.0 15.3 2.4 9.2 3.1 2.7 1 1 2 3 3 3 0 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 AAG03828.1 - 2.9 8.5 17.4 2.6 8.7 4.3 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_20 PF14691.6 AAG03829.1 - 2.4e-33 114.3 2.9 4e-33 113.6 2.9 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AAG03829.1 - 4e-31 108.3 0.4 6.2e-31 107.7 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG03829.1 - 1.2e-12 47.7 0.0 5e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG03829.1 - 8.7e-11 42.2 0.3 0.00063 20.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG03829.1 - 3.6e-10 39.9 2.0 1.2e-09 38.3 0.2 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAG03829.1 - 1.1e-06 28.5 2.6 2.2e-05 24.2 0.3 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG03829.1 - 6.5e-06 25.5 0.2 0.0001 21.6 0.1 2.5 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 AAG03829.1 - 8.9e-06 24.7 0.3 8.9e-06 24.7 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 AAG03829.1 - 1.5e-05 24.5 0.5 2.4e-05 23.8 0.1 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 AAG03829.1 - 2.2e-05 23.7 0.6 2.2e-05 23.7 0.6 2.8 2 1 2 4 4 4 1 FAD binding domain GIDA PF01134.22 AAG03829.1 - 8e-05 21.9 2.0 0.0036 16.4 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAG03829.1 - 9.9e-05 21.7 0.2 0.00018 20.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 AAG03829.1 - 0.00024 19.7 0.0 0.12 10.8 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like ApbA PF02558.16 AAG03829.1 - 0.0007 19.3 0.3 0.018 14.7 0.1 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 AAG03829.1 - 0.00088 18.7 4.2 0.0013 18.1 0.1 2.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAG03829.1 - 0.003 17.5 0.4 0.0073 16.2 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AAG03829.1 - 0.0031 16.6 0.2 0.0031 16.6 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 AAG03829.1 - 0.0085 16.5 0.1 1 9.8 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding DUF4147 PF13660.6 AAG03829.1 - 0.011 15.4 0.0 0.51 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) F420_oxidored PF03807.17 AAG03829.1 - 0.012 16.2 0.2 1.7 9.3 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 AAG03829.1 - 0.014 14.9 0.0 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 AAG03829.1 - 0.015 15.3 1.0 0.039 13.9 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 AAG03829.1 - 0.017 15.2 0.2 8.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer4_7 PF12838.7 AAG03829.1 - 0.037 14.6 0.4 0.037 14.6 0.4 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain 2-Hacid_dh_C PF02826.19 AAG03829.1 - 0.043 13.2 0.1 0.096 12.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 AAG03829.1 - 0.12 11.5 0.0 8.4 5.4 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 AAG03829.1 - 0.13 12.5 0.2 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Fer4_18 PF13746.6 AAG03829.1 - 0.55 10.4 7.7 0.6 10.3 0.7 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG03829.1 - 0.82 9.8 10.8 1.5 9.0 9.3 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG03829.1 - 1.5 9.1 8.7 0.4 10.9 0.2 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain Amidohydro_1 PF01979.20 AAG03830.1 - 1.6e-28 100.0 0.0 2e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG03830.1 - 3.6e-15 56.4 0.1 1.7e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Transp_cyt_pur PF02133.15 AAG03832.1 - 6.4e-92 308.6 30.6 7.7e-92 308.4 30.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5393 PF17371.2 AAG03832.1 - 0.18 9.9 0.1 0.25 9.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Peptidase_M20 PF01546.28 AAG03833.1 - 7.1e-39 133.6 0.8 9.2e-39 133.3 0.8 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 AAG03833.1 - 1.2e-07 31.6 0.0 5.5e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 AAG03833.1 - 1.1e-05 25.2 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Transposase_20 PF02371.16 AAG03834.1 - 7.2e-25 87.1 0.7 1.9e-24 85.8 0.7 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAG03834.1 - 5.4e-15 55.6 0.2 2.4e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 Transposase Cep57_MT_bd PF06657.13 AAG03834.1 - 0.0024 18.3 0.5 0.0056 17.1 0.1 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 HHH PF00633.23 AAG03834.1 - 0.02 14.7 0.1 0.063 13.2 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lzipper-MIP1 PF14389.6 AAG03834.1 - 0.021 15.1 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_transf_4 PF13439.6 AAG03834.1 - 0.054 13.5 0.4 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HalX PF08663.10 AAG03834.1 - 0.095 13.0 1.6 0.33 11.3 1.6 1.9 1 0 0 1 1 1 0 HalX domain DUF3287 PF11690.8 AAG03834.1 - 0.11 12.2 0.6 0.31 10.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ABC_tran_CTD PF16326.5 AAG03834.1 - 0.12 12.6 1.5 0.25 11.6 1.5 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AAG03834.1 - 0.4 10.8 3.0 0.23 11.5 0.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation CoA_transf_3 PF02515.17 AAG03835.1 - 4e-133 444.1 0.0 4.5e-133 443.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF4010 PF13194.6 AAG03835.1 - 0.0022 17.7 0.1 0.0035 17.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) SAM_4 PF18017.1 AAG03835.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Acyl-CoA_dh_N PF02771.16 AAG03836.1 - 5.8e-35 120.4 0.2 1.3e-34 119.3 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAG03836.1 - 6.4e-28 97.8 0.6 1e-27 97.2 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG03836.1 - 3.6e-22 78.4 0.0 6.7e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG03836.1 - 2e-05 24.9 0.2 4.7e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG03836.1 - 0.015 15.0 0.3 0.28 10.8 0.3 2.2 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal LysR_substrate PF03466.20 AAG03837.1 - 1.1e-40 139.3 1.1 1.4e-40 138.9 1.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03837.1 - 2.4e-20 72.2 1.6 1.2e-19 70.0 2.5 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_50 PF18024.1 AAG03837.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAG03837.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain 4HBT PF03061.22 AAG03838.1 - 5.9e-13 49.0 0.0 8.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily PHO4 PF01384.20 AAG03839.1 - 5.4e-90 301.8 5.7 6.2e-90 301.6 3.6 2.0 2 1 0 2 2 2 1 Phosphate transporter family NfeD PF01957.18 AAG03840.1 - 1.1e-10 41.8 1.2 1.9e-09 37.8 1.2 2.8 3 0 0 3 3 3 1 NfeD-like C-terminal, partner-binding CPP1-like PF11833.8 AAG03840.1 - 2.8 7.5 5.6 13 5.4 5.0 2.2 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Band_7 PF01145.25 AAG03841.1 - 6.3e-34 117.5 5.5 7.7e-34 117.2 5.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AAG03841.1 - 0.0068 16.1 0.6 0.013 15.2 0.6 1.5 1 1 0 1 1 1 1 SPFH domain-Band 7 family FUSC-like PF12805.7 AAG03843.1 - 9.4e-120 399.0 20.0 1.8e-114 381.6 3.3 3.2 2 1 0 2 2 2 2 FUSC-like inner membrane protein yccS FUSC_2 PF13515.6 AAG03843.1 - 1.1e-21 77.3 27.3 1.6e-21 76.7 11.8 2.6 2 1 0 2 2 2 2 Fusaric acid resistance protein-like FUSC PF04632.12 AAG03843.1 - 9.8e-18 64.0 9.0 9.8e-18 64.0 9.0 3.4 3 1 1 4 4 4 1 Fusaric acid resistance protein family ALMT PF11744.8 AAG03843.1 - 0.00016 20.6 0.7 0.00016 20.6 0.7 2.1 2 1 0 2 2 2 1 Aluminium activated malate transporter DEAD PF00270.29 AAG03844.1 - 2.1e-48 164.4 0.0 2.7e-47 160.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG03844.1 - 1.5e-27 96.1 0.0 1.4e-25 89.8 0.2 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DbpA PF03880.15 AAG03844.1 - 4.3e-24 84.3 0.0 8.6e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 AAG03844.1 - 2.4e-07 30.9 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAG03844.1 - 0.0069 16.7 0.0 4.9 7.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain ERCC3_RAD25_C PF16203.5 AAG03844.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 AAG03844.1 - 0.035 13.4 0.0 0.085 12.2 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 AAG03844.1 - 0.07 13.0 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Helicase CSD PF00313.22 AAG03845.1 - 4.5e-29 100.1 1.5 4.9e-29 100.0 1.5 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAG03845.1 - 0.0049 16.5 0.3 0.0056 16.3 0.3 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 AAG03845.1 - 0.0097 15.9 0.3 0.013 15.4 0.3 1.2 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF Zn_protease PF05618.11 AAG03846.1 - 4.4e-49 165.9 0.0 5.6e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease MFS_1 PF07690.16 AAG03847.1 - 2.5e-48 164.8 38.7 2.5e-48 164.8 38.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG03847.1 - 6.6e-06 25.7 6.7 2e-05 24.0 6.7 1.8 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 AAG03847.1 - 1.6e-05 23.5 7.7 1.6e-05 23.5 7.7 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector Sugar_tr PF00083.24 AAG03847.1 - 4.2e-05 22.6 5.0 4.2e-05 22.6 5.0 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 AAG03847.1 - 0.00047 18.8 3.9 0.00047 18.8 3.9 2.5 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 AAG03847.1 - 0.066 11.6 13.4 0.066 11.6 10.4 2.2 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 AAG03847.1 - 0.12 10.7 1.2 2.9 6.1 0.1 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AAA_2 PF07724.14 AAG03848.1 - 1e-57 195.0 1.8 2.9e-54 183.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAG03848.1 - 2.8e-34 117.2 4.4 7e-33 112.7 4.0 3.0 2 1 0 2 2 2 1 AAA lid domain AAA PF00004.29 AAG03848.1 - 2.9e-27 95.7 0.9 1.2e-15 58.1 0.0 3.1 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 AAG03848.1 - 2.3e-25 88.5 2.5 4.8e-15 55.4 0.1 2.8 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 AAG03848.1 - 1.8e-22 79.1 1.4 7.2e-22 77.3 1.4 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AAG03848.1 - 9.8e-19 67.7 0.2 6.1e-11 42.5 0.0 3.2 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AAG03848.1 - 1.3e-12 47.8 0.2 5.7e-08 32.6 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 AAG03848.1 - 6.9e-08 32.1 0.0 5.1e-05 22.8 0.1 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 AAG03848.1 - 8.6e-07 28.6 0.0 0.15 11.5 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAG03848.1 - 1.3e-06 28.3 0.0 0.065 13.0 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 AAG03848.1 - 1.8e-06 28.4 15.3 0.0017 18.7 0.1 5.7 4 2 2 6 6 6 2 AAA ATPase domain AAA_28 PF13521.6 AAG03848.1 - 1.9e-06 28.2 0.6 0.013 15.7 0.0 3.7 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 AAG03848.1 - 2.9e-06 27.6 6.2 0.031 14.6 0.2 5.1 3 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 AAG03848.1 - 3.1e-06 27.7 3.3 0.025 15.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain RuvB_N PF05496.12 AAG03848.1 - 3.7e-06 26.8 3.5 0.19 11.5 0.0 4.6 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 AAG03848.1 - 1.5e-05 25.0 0.0 0.081 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AAG03848.1 - 4.3e-05 23.5 0.1 0.41 10.5 0.0 3.0 2 1 1 3 3 3 2 RsgA GTPase Zeta_toxin PF06414.12 AAG03848.1 - 7.4e-05 22.1 0.0 0.07 12.4 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 AAG03848.1 - 0.00017 21.6 0.0 0.11 12.4 0.0 3.1 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 AAG03848.1 - 0.00018 21.7 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 AAG03848.1 - 0.0002 20.8 0.2 0.4 10.0 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AAG03848.1 - 0.00025 20.9 0.1 0.21 11.4 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAG03848.1 - 0.00026 21.2 0.0 0.49 10.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 AAG03848.1 - 0.00041 19.6 1.5 0.038 13.2 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF815) TsaE PF02367.17 AAG03848.1 - 0.00042 20.3 0.1 1 9.3 0.0 2.8 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 AAG03848.1 - 0.00043 20.6 0.0 2 8.8 0.0 3.0 3 0 0 3 3 3 2 RNA helicase AAA_24 PF13479.6 AAG03848.1 - 0.00053 19.8 0.0 0.38 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 AAG03848.1 - 0.00097 19.7 0.1 0.63 10.6 0.0 3.1 3 0 0 3 3 2 1 ABC transporter AAA_25 PF13481.6 AAG03848.1 - 0.001 18.7 0.1 0.074 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AAG03848.1 - 0.0019 18.1 6.4 2.5 7.9 0.1 4.1 3 2 1 4 4 3 1 ATPase domain predominantly from Archaea ResIII PF04851.15 AAG03848.1 - 0.0025 17.9 0.3 4.5 7.2 0.0 4.1 2 2 2 4 4 4 0 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.6 AAG03848.1 - 0.0032 17.2 0.0 1 9.1 0.0 2.7 3 0 0 3 3 2 1 DNA polymerase III, delta subunit AAA_23 PF13476.6 AAG03848.1 - 0.0049 17.4 9.7 0.99 9.9 0.0 3.9 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 AAG03848.1 - 0.0086 15.3 4.1 1.4 8.0 0.2 3.5 3 1 0 3 3 3 1 TIP49 P-loop domain AAA_29 PF13555.6 AAG03848.1 - 0.012 15.3 0.0 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 AAG03848.1 - 0.014 15.2 0.6 3.6 7.3 0.0 3.7 3 1 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 AAG03848.1 - 0.02 14.0 0.0 5 6.1 0.0 2.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NADH-UOR_E PF16514.5 AAG03848.1 - 0.02 15.2 0.3 13 6.2 0.1 3.0 3 0 0 3 3 2 0 putative NADH-ubiquinone oxidoreductase chain E T2SSE PF00437.20 AAG03848.1 - 0.031 13.3 0.5 0.15 11.1 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF3572 PF12096.8 AAG03848.1 - 0.062 13.5 0.3 2.8 8.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3572) PduV-EutP PF10662.9 AAG03848.1 - 0.07 12.9 0.1 6.1 6.6 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran_CTD PF16326.5 AAG03848.1 - 0.074 13.3 12.6 0.24 11.7 8.8 3.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain AAA_19 PF13245.6 AAG03848.1 - 0.096 13.0 4.2 0.36 11.1 0.3 3.2 3 2 0 3 3 2 0 AAA domain Bac_DnaA_C PF08299.11 AAG03848.1 - 0.12 12.5 0.1 48 4.1 0.0 3.4 3 0 0 3 3 3 0 Bacterial dnaA protein helix-turn-helix YfcL PF08891.11 AAG03848.1 - 0.16 12.4 1.4 1.6 9.2 0.2 3.3 2 1 1 3 3 2 0 YfcL protein NTPase_1 PF03266.15 AAG03848.1 - 0.31 10.9 4.6 6.8 6.6 0.1 3.6 3 1 0 3 3 3 0 NTPase WXG100 PF06013.12 AAG03848.1 - 0.97 9.7 4.9 15 5.9 3.3 3.1 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF2780 PF11075.8 AAG03849.1 - 1.6e-43 148.9 14.1 2e-43 148.6 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) Acyltransferase PF01553.21 AAG03850.1 - 1.5e-15 57.0 0.0 2.1e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Zn_protease PF05618.11 AAG03851.1 - 4.4e-54 182.1 0.0 5.6e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease gag-asp_proteas PF13975.6 AAG03851.1 - 0.047 14.3 0.0 0.082 13.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Response_reg PF00072.24 AAG03852.1 - 2.9e-24 85.4 0.0 4.1e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG03852.1 - 8.3e-21 73.9 0.1 1.5e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HisKA PF00512.25 AAG03853.1 - 1.3e-12 47.6 2.7 1.4e-12 47.5 0.6 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAG03853.1 - 9.5e-11 42.2 0.0 4.3e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAG03853.1 - 1.5e-07 31.7 0.2 1.5e-07 31.7 0.2 2.4 2 0 0 2 2 2 1 HAMP domain dCache_1 PF02743.18 AAG03853.1 - 3.3e-05 23.8 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cache domain sCache_3_2 PF17203.4 AAG03853.1 - 0.00024 21.3 1.3 0.00039 20.6 0.1 2.0 2 0 0 2 2 2 1 Single cache domain 3 GAF_2 PF13185.6 AAG03853.1 - 0.0062 16.8 0.0 0.039 14.3 0.0 2.2 2 0 0 2 2 2 1 GAF domain sCache_like PF16736.5 AAG03853.1 - 0.0066 16.5 0.0 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 Single Cache-like GAF PF01590.26 AAG03853.1 - 0.049 14.3 0.0 0.15 12.7 0.0 1.9 2 0 0 2 2 2 0 GAF domain HWE_HK PF07536.14 AAG03853.1 - 0.095 13.4 0.5 0.36 11.6 0.5 2.0 1 0 0 1 1 1 0 HWE histidine kinase sCache_3_3 PF17202.4 AAG03853.1 - 0.14 12.6 0.1 0.37 11.2 0.0 1.7 2 0 0 2 2 1 0 Single cache domain 3 LapA_dom PF06305.11 AAG03853.1 - 0.54 10.1 5.4 0.079 12.8 0.7 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CreD PF06123.12 AAG03854.1 - 3.7e-166 553.2 0.0 4.2e-166 553.0 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein CreD GST_N_3 PF13417.6 AAG03856.1 - 3e-18 66.0 0.0 5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG03856.1 - 1.2e-11 44.7 0.0 2.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAG03856.1 - 3e-07 30.4 2.4 6.9e-07 29.2 2.4 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAG03856.1 - 1.9e-06 28.1 0.0 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 AAG03856.1 - 0.026 14.9 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 AAG03856.1 - 0.065 14.0 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain SGL PF08450.12 AAG03857.1 - 7.1e-09 35.6 0.2 0.00023 20.8 0.1 4.0 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 AAG03857.1 - 9.8e-06 25.2 1.3 4.4 7.9 0.0 5.5 6 0 0 6 6 6 1 Two component regulator propeller DUF5074 PF16819.5 AAG03857.1 - 2.8e-05 24.1 0.0 0.012 15.6 0.0 3.7 3 2 2 5 5 5 1 Domain of unknown function (DUF5074) Phytase-like PF13449.6 AAG03857.1 - 0.00062 19.8 0.1 3.3 7.6 0.0 3.8 1 1 1 2 2 2 2 Esterase-like activity of phytase NHL PF01436.21 AAG03857.1 - 0.0022 17.9 0.8 12 6.1 0.0 4.4 5 0 0 5 5 5 2 NHL repeat PP2C_2 PF13672.6 AAG03858.1 - 1e-42 146.2 0.2 1.5e-42 145.6 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C TonB_dep_Rec PF00593.24 AAG03859.1 - 1.8e-62 212.8 46.8 2.5e-62 212.3 46.8 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG03859.1 - 4.6e-19 69.0 0.1 1.6e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG03859.1 - 0.0035 17.1 0.0 0.012 15.4 0.0 2.0 1 1 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AAG03860.1 - 1.4e-17 64.1 0.1 3e-17 63.0 0.1 1.6 2 0 0 2 2 2 1 FecR protein DUF4880 PF16220.5 AAG03860.1 - 2.8e-14 52.7 8.0 2.8e-14 52.7 8.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) Sigma70_r4_2 PF08281.12 AAG03861.1 - 1.5e-15 56.6 0.2 2.7e-15 55.8 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG03861.1 - 1.6e-13 50.2 0.3 2.8e-13 49.4 0.3 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG03861.1 - 3.2e-08 32.9 0.0 5.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG03861.1 - 5.9e-05 22.7 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AAG03861.1 - 0.00019 21.4 0.1 0.00028 20.8 0.1 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 AAG03861.1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAG03861.1 - 0.015 15.1 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r3 PF04539.16 AAG03861.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 MerR PF00376.23 AAG03861.1 - 0.033 14.0 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein FaeA PF04703.12 AAG03861.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 FaeA-like protein HTH_Tnp_ISL3 PF13542.6 AAG03861.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AAG03861.1 - 0.064 13.0 1.1 0.66 9.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_31 PF13560.6 AAG03861.1 - 0.11 12.9 6.6 0.33 11.3 0.4 3.0 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 AAG03861.1 - 0.13 12.4 0.3 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 AAG03861.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family GST_N_3 PF13417.6 AAG03862.1 - 3.2e-21 75.5 0.0 1.4e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG03862.1 - 7.2e-16 58.2 0.0 1.3e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAG03862.1 - 3.6e-09 36.8 0.0 8.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 AAG03862.1 - 4.8e-05 24.0 0.0 0.00011 22.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 AAG03862.1 - 6.9e-05 23.0 0.0 0.00044 20.4 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AAG03862.1 - 0.0049 17.2 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 AAG03862.1 - 0.008 16.2 0.9 0.12 12.4 0.1 2.4 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain 4HBT PF03061.22 AAG03863.1 - 3.8e-16 59.2 0.2 5.5e-16 58.7 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAG03863.1 - 0.00037 20.8 0.1 0.00043 20.6 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily TetR_N PF00440.23 AAG03864.1 - 3.2e-11 42.8 0.1 7.5e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 AAG03864.1 - 0.0021 17.9 0.2 0.0033 17.4 0.2 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain MerR-DNA-bind PF09278.11 AAG03864.1 - 0.48 11.0 5.6 58 4.3 0.3 3.2 3 0 0 3 3 3 0 MerR, DNA binding Transp_cyt_pur PF02133.15 AAG03865.1 - 4.3e-78 263.1 36.8 5.2e-78 262.8 36.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LysR_substrate PF03466.20 AAG03866.1 - 6.4e-25 87.8 8.9 6.4e-25 87.8 8.9 2.0 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03866.1 - 2.2e-14 53.1 0.6 6.4e-14 51.7 0.6 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Acetyltransf_1 PF00583.25 AAG03867.1 - 2.9e-19 69.4 0.1 3.5e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG03867.1 - 5.5e-09 36.3 0.0 7.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG03867.1 - 5.7e-08 32.7 0.0 7.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG03867.1 - 0.00016 21.6 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 AAG03867.1 - 0.0025 17.9 1.0 0.0046 17.1 1.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG03867.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AAG03867.1 - 0.041 14.0 0.0 0.053 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 AAG03867.1 - 0.2 11.1 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase LysR_substrate PF03466.20 AAG03868.1 - 5.6e-26 91.2 6.9 9.4e-26 90.5 6.9 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03868.1 - 9.1e-19 67.2 0.9 1.6e-18 66.4 0.9 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Abhydrolase_1 PF00561.20 AAG03869.1 - 3.9e-23 82.4 0.0 7.1e-18 65.2 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG03869.1 - 6.6e-12 46.5 11.3 8.1e-12 46.2 11.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG03869.1 - 5.8e-11 42.1 0.1 8.9e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAG03869.1 - 6.1e-06 25.1 0.0 7.7e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 AAG03869.1 - 0.16 12.1 0.0 0.57 10.3 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein RPA_interact_N PF14766.6 AAG03870.1 - 0.044 13.4 0.8 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Rubredoxin_2 PF18073.1 AAG03870.1 - 0.15 11.8 0.6 0.15 11.8 0.6 2.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain Malate_synthase PF01274.22 AAG03871.1 - 2e-178 594.0 0.1 2.3e-178 593.8 0.1 1.0 1 0 0 1 1 1 1 Malate synthase Acetyltransf_1 PF00583.25 AAG03872.1 - 1.1e-14 54.6 0.0 1.4e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG03872.1 - 3.2e-11 43.3 0.0 5.2e-11 42.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG03872.1 - 6.9e-11 42.4 0.0 1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAG03872.1 - 4.9e-10 39.2 0.0 7.1e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 AAG03872.1 - 1.5e-06 28.1 0.1 3.8e-06 26.8 0.0 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 AAG03872.1 - 5.9e-05 23.8 0.0 7.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG03872.1 - 0.0076 16.4 0.0 0.0088 16.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAG03872.1 - 0.06 13.4 0.0 0.085 12.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AAG03872.1 - 0.065 13.2 0.0 0.098 12.7 0.0 1.4 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 AAG03872.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ACT_6 PF13740.6 AAG03873.1 - 5.6e-18 64.7 1.4 3.7e-11 42.9 0.0 2.5 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 AAG03873.1 - 1.2e-12 48.3 0.0 3e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AAG03873.1 - 3.9e-11 42.5 0.6 5.6e-07 29.2 0.1 3.2 3 1 0 3 3 3 2 ACT domain ACT_7 PF13840.6 AAG03873.1 - 7.4e-05 22.5 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 1 ACT domain DUF4349 PF14257.6 AAG03873.1 - 0.035 13.6 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF493 PF04359.14 AAG03873.1 - 0.097 13.3 0.0 4.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF493) EamA PF00892.20 AAG03874.1 - 2.7e-21 76.2 29.3 3.5e-16 59.6 6.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 AAG03874.1 - 0.08 12.1 0.9 0.12 11.5 0.9 1.3 1 0 0 1 1 1 0 Nucleotide-sugar transporter RseC_MucC PF04246.12 AAG03874.1 - 0.77 9.7 11.4 1.8 8.5 0.5 3.2 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC APH PF01636.23 AAG03875.1 - 1.9e-38 132.8 6.5 2.2e-38 132.6 5.9 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 AAG03875.1 - 0.0061 15.9 0.1 0.044 13.1 0.0 2.0 1 1 1 2 2 2 1 Ecdysteroid kinase TOBE PF03459.17 AAG03876.1 - 1.4e-32 111.7 0.6 3.2e-16 59.4 0.1 2.4 2 0 0 2 2 2 2 TOBE domain HTH_1 PF00126.27 AAG03876.1 - 1e-17 63.8 0.1 2.3e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family TOBE_2 PF08402.10 AAG03876.1 - 9.5e-05 22.5 0.0 0.047 13.9 0.0 2.8 1 1 1 2 2 2 2 TOBE domain HTH_29 PF13551.6 AAG03876.1 - 0.0087 16.1 0.4 0.021 14.8 0.4 1.7 1 0 0 1 1 1 1 Winged helix-turn helix NUMOD1 PF07453.13 AAG03876.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 NUMOD1 domain DUF2279 PF10043.9 AAG03877.1 - 2.2e-06 28.3 0.9 2.8e-06 28.0 0.9 1.1 1 0 0 1 1 1 1 Predicted periplasmic lipoprotein (DUF2279) VanZ PF04892.12 AAG03877.1 - 0.15 12.7 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 VanZ like family Pribosyltran PF00156.27 AAG03878.1 - 1.2e-08 34.6 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AAG03878.1 - 0.16 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase DZR PF12773.7 AAG03878.1 - 0.21 11.6 8.1 0.39 10.8 8.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 AAG03878.1 - 7.1 6.6 8.4 0.88 9.5 3.5 2.1 2 1 1 3 3 3 0 HIT zinc finger DUF3185 PF11381.8 AAG03879.1 - 1.6 8.8 11.4 0.51 10.4 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3185) LysR_substrate PF03466.20 AAG03880.1 - 6.4e-46 156.4 1.2 8e-46 156.0 1.2 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03880.1 - 1.9e-18 66.2 0.5 1.9e-18 66.2 0.5 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LamB_YcsF PF03746.16 AAG03881.1 - 3e-90 302.1 0.0 3.4e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Biotin_lipoyl PF00364.22 AAG03882.1 - 1.4e-14 53.7 0.1 1.5e-14 53.6 0.1 1.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAG03882.1 - 3.6e-05 23.5 1.8 0.00068 19.4 0.2 2.6 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG03882.1 - 0.013 14.8 0.1 0.02 14.1 0.1 1.4 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Peptidase_M23 PF01551.22 AAG03882.1 - 0.019 15.1 0.2 4.5 7.5 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 QRPTase_N PF02749.16 AAG03882.1 - 0.023 14.8 0.2 0.04 14.0 0.2 1.4 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 AAG03882.1 - 0.13 12.1 0.3 0.29 11.0 0.3 1.6 1 1 1 2 2 2 0 Glycine cleavage H-protein CPSase_L_D2 PF02786.17 AAG03883.1 - 2.6e-73 246.0 0.0 4.5e-73 245.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAG03883.1 - 7.2e-42 142.4 0.1 1.5e-41 141.4 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAG03883.1 - 3.5e-39 133.2 0.0 6.8e-39 132.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AAG03883.1 - 3e-09 36.7 0.0 1.3e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAG03883.1 - 9.3e-06 25.3 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAG03883.1 - 0.00049 20.2 0.0 0.00071 19.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 AAG03883.1 - 0.013 15.7 0.2 0.074 13.2 0.0 2.5 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 DUF1771 PF08590.10 AAG03883.1 - 1.5 9.2 5.7 12 6.3 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) CT_C_D PF02682.16 AAG03884.1 - 4.5e-49 166.9 0.0 5.9e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D CT_A_B PF02626.15 AAG03885.1 - 2.4e-87 292.9 0.3 2.7e-87 292.7 0.3 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B Fimbrial PF00419.20 AAG03886.1 - 3.2e-21 76.2 0.0 5.8e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AAG03887.1 - 6.6e-17 62.2 0.1 1.9e-16 60.7 0.1 1.7 2 0 0 2 2 2 1 Fimbrial protein PapD_N PF00345.20 AAG03888.1 - 1e-20 73.9 0.0 1.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAG03888.1 - 5.7e-14 52.2 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain BATS PF06968.13 AAG03889.1 - 2.4e-21 75.6 0.1 8.1e-21 74.0 0.1 1.9 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 AAG03889.1 - 1.5e-14 54.7 0.0 4.5e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 AAG03890.1 - 2.3e-52 178.4 0.0 2.6e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAG03890.1 - 1.3e-05 24.7 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAG03890.1 - 0.024 13.2 0.0 0.048 12.2 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AAG03890.1 - 0.026 13.8 0.0 0.14 11.4 0.0 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.20 AAG03890.1 - 0.065 12.0 0.0 0.15 10.8 0.0 1.5 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Abhydrolase_6 PF12697.7 AAG03891.1 - 1.6e-09 38.7 10.3 2.3e-09 38.2 10.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG03891.1 - 6.6e-07 29.2 0.0 6.2e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG03891.1 - 3.5e-05 23.2 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAG03891.1 - 0.002 18.3 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 AAG03891.1 - 0.0022 17.8 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2019 PF09450.10 AAG03891.1 - 0.13 12.2 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) UPF0227 PF05728.12 AAG03891.1 - 0.18 11.7 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Methyltransf_11 PF08241.12 AAG03892.1 - 2.7e-24 85.6 0.0 4.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG03892.1 - 6.3e-21 74.9 0.1 1.4e-20 73.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG03892.1 - 2e-14 53.6 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG03892.1 - 6.7e-13 48.8 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG03892.1 - 3.1e-12 47.1 0.0 6.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAG03892.1 - 5.8e-11 42.2 0.0 9.1e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 AAG03892.1 - 0.00018 20.2 0.0 0.00022 19.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 AAG03892.1 - 0.00031 20.3 0.0 0.0041 16.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_8 PF05148.15 AAG03892.1 - 0.00073 19.5 0.0 0.0013 18.7 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 AAG03892.1 - 0.0014 18.8 0.0 0.0031 17.6 0.0 1.5 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 AAG03892.1 - 0.028 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 AAG03892.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.3 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 AAG03892.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AAA_26 PF13500.6 AAG03893.1 - 2.6e-36 125.3 0.0 2.9e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAG03893.1 - 3e-11 43.5 0.0 4.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 AAG03893.1 - 0.0067 15.7 1.0 0.02 14.2 0.5 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain Acyl-CoA_dh_C PF12806.7 AAG03895.1 - 2.4e-35 121.4 7.1 2.4e-35 121.4 7.1 1.8 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAG03895.1 - 8.8e-20 71.4 1.5 8.8e-20 71.4 1.5 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG03895.1 - 2.1e-19 69.5 0.1 5.5e-18 65.0 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG03895.1 - 5e-13 49.7 1.2 3e-12 47.2 0.1 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 AAG03895.1 - 3.6e-11 42.9 0.2 7.5e-11 41.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 AAG03895.1 - 0.018 15.3 1.3 0.31 11.3 0.0 2.6 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_C PF12806.7 AAG03896.1 - 1.3e-34 119.1 8.6 2.6e-34 118.0 8.6 1.6 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAG03896.1 - 1.9e-25 89.8 1.9 1.9e-25 89.8 1.9 3.2 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG03896.1 - 3.8e-17 62.3 0.0 8e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG03896.1 - 3.2e-12 47.1 0.1 1.6e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 AAG03896.1 - 6.7e-09 35.6 0.1 1.3e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 AAG03896.1 - 0.0013 19.0 0.4 0.0035 17.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_C PF12806.7 AAG03897.1 - 2.6e-35 121.3 1.3 6.3e-35 120.0 1.3 1.7 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAG03897.1 - 3.3e-22 79.3 1.3 2.7e-21 76.3 1.3 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG03897.1 - 8.4e-17 61.2 0.0 2.3e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_DH_N PF12418.8 AAG03897.1 - 2.4e-12 46.7 0.1 5.2e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_N PF02771.16 AAG03897.1 - 1e-10 42.2 0.7 2.4e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAG03897.1 - 0.11 12.8 0.4 0.29 11.4 0.1 2.0 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Cytochrom_D1 PF02239.16 AAG03898.1 - 2.5e-149 496.8 0.0 3.1e-149 496.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome D1 heme domain Cytochrome_CBB3 PF13442.6 AAG03898.1 - 1.2e-13 51.2 0.1 3.1e-13 49.8 0.1 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG03898.1 - 8.4e-06 26.8 1.9 0.00014 22.9 1.9 2.3 1 1 0 1 1 1 1 Cytochrome c PD40 PF07676.12 AAG03898.1 - 2.6e-05 24.0 2.4 0.003 17.5 0.1 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 AAG03898.1 - 5.8e-05 22.3 0.0 3.8 6.5 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF1513) ANAPC4_WD40 PF12894.7 AAG03898.1 - 9.8e-05 22.6 0.0 0.23 11.8 0.0 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 AAG03898.1 - 0.0033 17.9 5.4 2 9.0 0.0 4.3 4 0 0 4 4 4 1 PQQ-like domain WD40 PF00400.32 AAG03898.1 - 0.022 15.6 0.4 88 4.2 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Lactonase PF10282.9 AAG03898.1 - 0.11 11.8 0.0 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller VID27 PF08553.10 AAG03898.1 - 0.25 10.4 0.0 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain TP_methylase PF00590.20 AAG03899.1 - 5.8e-50 170.2 0.4 6.8e-50 169.9 0.4 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 AAG03899.1 - 0.0022 18.4 0.0 0.0032 17.8 0.0 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Radical_SAM PF04055.21 AAG03900.1 - 1.8e-25 90.2 0.0 2.8e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAG03900.1 - 8.7e-11 42.2 0.0 2.5e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAG03900.1 - 8.2e-09 35.6 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 AAG03900.1 - 0.027 15.0 0.1 0.086 13.4 0.1 1.9 1 1 0 1 1 1 0 Iron-sulfur cluster-binding domain Amidohydro_2 PF04909.14 AAG03900.1 - 0.029 14.1 0.1 0.22 11.3 0.1 2.1 1 1 0 1 1 1 0 Amidohydrolase AsnC_trans_reg2 PF17805.1 AAG03901.1 - 9.9e-22 76.9 0.0 1.7e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 AsnC-like ligand binding domain HTH_24 PF13412.6 AAG03901.1 - 0.087 12.4 0.2 0.22 11.1 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAG03901.1 - 0.12 12.3 1.2 0.33 10.9 1.1 1.9 1 1 0 1 1 1 0 MarR family AsnC_trans_reg2 PF17805.1 AAG03902.1 - 1.2e-18 67.0 0.0 2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AAG03902.1 - 7.6e-06 25.7 1.1 7.6e-06 25.7 1.1 2.4 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain AsnC_trans_reg2 PF17805.1 AAG03903.1 - 2.5e-21 75.6 0.0 3.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AAG03903.1 - 0.04 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain AsnC_trans_reg2 PF17805.1 AAG03904.1 - 1.6e-21 76.2 0.0 1.6e-20 73.1 0.0 1.9 2 0 0 2 2 2 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AAG03904.1 - 2.7e-08 33.5 3.9 2.8e-08 33.5 0.6 2.5 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 AAG03904.1 - 0.014 15.4 0.1 0.062 13.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain AsnC_trans_reg PF01037.21 AAG03904.1 - 0.033 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAG03904.1 - 0.036 13.6 0.9 0.1 12.2 0.0 2.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 AAG03904.1 - 0.066 12.8 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Cytochrom_D1 PF02239.16 AAG03905.1 - 2.7e-147 490.1 0.0 3.1e-147 489.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome D1 heme domain Lactonase PF10282.9 AAG03905.1 - 0.001 18.4 0.0 0.0037 16.6 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller FlaG PF03646.15 AAG03905.1 - 0.075 13.2 0.0 17 5.7 0.0 2.3 2 0 0 2 2 2 0 FlaG protein Cytochrome_CBB3 PF13442.6 AAG03906.1 - 7.6e-10 39.0 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_CBB3 PF13442.6 AAG03907.1 - 1.3e-06 28.6 0.1 1.6e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG03907.1 - 4.1e-06 27.9 0.1 7.5e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c Haem_bd PF14376.6 AAG03907.1 - 0.064 13.2 0.0 1.2 9.1 0.0 2.0 1 1 1 2 2 2 0 Haem-binding domain Cytochrom_D1 PF02239.16 AAG03908.1 - 3.9e-167 555.4 0.6 4.7e-167 555.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome D1 heme domain Cytochrome_CBB3 PF13442.6 AAG03908.1 - 2.1e-11 44.0 0.0 6.6e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG03908.1 - 0.00062 20.9 0.1 0.003 18.7 0.1 2.2 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 AAG03908.1 - 0.036 13.8 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c-550 domain AAA_5 PF07728.14 AAG03909.1 - 1.3e-32 112.7 0.0 1.8e-31 109.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 AAG03909.1 - 1e-30 105.8 0.8 2.2e-30 104.7 0.8 1.6 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Mg_chelatase PF01078.21 AAG03909.1 - 4.2e-07 29.6 0.0 0.0034 16.8 0.0 3.1 1 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AAG03909.1 - 2e-05 24.4 0.0 9.3e-05 22.2 0.0 2.0 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 AAG03909.1 - 3.2e-05 23.8 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 AAG03909.1 - 0.0015 19.0 0.0 0.0029 18.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG03909.1 - 0.0015 18.9 0.1 0.008 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 AAG03909.1 - 0.0016 18.4 0.0 0.005 16.8 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 AAG03909.1 - 0.0018 17.8 0.0 0.0086 15.6 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_6 PF12774.7 AAG03909.1 - 0.013 14.5 0.0 0.077 12.0 0.0 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 AAG03909.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 2 0 0 2 2 1 0 RNA helicase MCM PF00493.23 AAG03909.1 - 0.022 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 AAG03909.1 - 0.029 14.3 0.0 0.25 11.2 0.0 2.4 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 AAG03909.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 AAG03909.1 - 0.041 13.8 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 AAG03909.1 - 0.13 12.4 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 AAG03909.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain COX3 PF00510.18 AAG03910.1 - 1.4e-18 67.7 7.1 1.8e-18 67.3 7.1 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III FAM165 PF14981.6 AAG03910.1 - 0.044 13.6 1.1 0.33 10.8 0.1 2.3 2 0 0 2 2 2 0 FAM165 family TraL PF07178.11 AAG03910.1 - 2.2 8.8 10.9 0.94 10.0 2.8 2.5 3 0 0 3 3 3 0 TraL protein DUF805 PF05656.14 AAG03910.1 - 7.1 7.1 9.4 34 4.9 9.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) COX4_pro PF03626.14 AAG03911.1 - 3.3e-12 46.6 3.9 3.9e-12 46.4 3.9 1.1 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV Cytochrom_C PF00034.21 AAG03912.1 - 2.3e-09 38.3 0.0 3.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG03912.1 - 8.4e-06 26.0 0.0 1.6e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III COX1 PF00115.20 AAG03913.1 - 1.8e-79 267.6 61.2 2.2e-79 267.3 61.2 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I VWA PF00092.28 AAG03914.1 - 3.7e-05 24.0 0.0 5.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 AAG03914.1 - 0.00099 18.6 0.1 0.02 14.3 0.3 2.3 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 AAG03914.1 - 0.001 19.7 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.7 AAG03915.1 - 0.023 14.7 2.4 0.028 14.4 2.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF4131 PF13567.6 AAG03915.1 - 0.067 12.8 0.1 0.067 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Zn_ribbon_2 PF12674.7 AAG03915.1 - 0.081 13.6 0.1 0.081 13.6 0.1 1.7 2 0 0 2 2 2 0 Putative zinc ribbon domain XAF1_C PF18608.1 AAG03915.1 - 0.12 12.0 0.3 0.12 12.0 0.3 1.6 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain DUF2616 PF11077.8 AAG03915.1 - 0.19 11.5 1.9 0.26 11.0 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) cNMP_binding PF00027.29 AAG03916.1 - 4.3e-19 68.4 0.0 7e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAG03916.1 - 1.1e-15 57.4 0.0 2.3e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAG03916.1 - 0.0081 16.5 0.0 0.049 14.0 0.0 2.2 1 1 1 2 2 2 1 Transcriptional regulator LysR_substrate PF03466.20 AAG03917.1 - 2.2e-38 131.7 6.3 2.2e-38 131.7 6.3 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG03917.1 - 2.3e-21 75.5 0.7 2.3e-21 75.5 0.7 2.6 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG03917.1 - 0.015 15.2 0.3 0.075 12.9 0.1 2.2 2 0 0 2 2 2 0 MarR family HTH_30 PF13556.6 AAG03917.1 - 0.09 12.6 0.4 0.29 11.0 0.1 2.1 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 AAG03917.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MOSC PF03473.17 AAG03918.1 - 1.7e-21 76.6 0.0 2.6e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 AAG03918.1 - 1.3e-15 56.9 0.3 3e-15 55.8 0.3 1.6 1 0 0 1 1 1 1 3-alpha domain Aminotran_3 PF00202.21 AAG03919.1 - 3.4e-80 269.7 0.0 5.9e-80 268.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAG03919.1 - 0.00065 19.1 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAG03919.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V GATase PF00117.28 AAG03920.1 - 2.1e-13 50.5 0.0 2.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAG03920.1 - 0.00027 20.8 0.2 0.00046 20.0 0.2 1.4 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 AAG03920.1 - 0.00056 19.6 0.0 0.00078 19.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AAG03920.1 - 0.00085 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF1652 PF07865.11 AAG03921.1 - 0.04 13.7 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) DUF3509 PF12021.8 AAG03921.1 - 0.09 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) PAS_9 PF13426.7 AAG03922.1 - 1.3e-20 73.5 0.0 4.5e-08 33.3 0.0 3.4 3 0 0 3 3 3 3 PAS domain GerE PF00196.19 AAG03922.1 - 4.6e-18 64.5 0.0 9.4e-18 63.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family PAS_8 PF13188.7 AAG03922.1 - 1.4e-16 60.1 0.7 5.7e-07 29.4 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 AAG03922.1 - 1.5e-16 60.6 3.1 1.8e-05 24.9 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS PF00989.25 AAG03922.1 - 5e-16 58.7 0.0 9e-05 22.4 0.0 3.4 3 0 0 3 3 3 3 PAS fold Sigma70_r4_2 PF08281.12 AAG03922.1 - 5.2e-07 29.2 0.0 1.9e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 PAS_3 PF08447.12 AAG03922.1 - 8.5e-05 22.8 0.0 0.41 11.0 0.0 3.6 2 1 0 2 2 2 2 PAS fold HTH_40 PF14493.6 AAG03922.1 - 0.00055 20.3 0.0 0.0017 18.8 0.0 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAG03922.1 - 0.0013 18.2 0.1 0.0058 16.1 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 AAG03922.1 - 0.0043 16.8 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG03922.1 - 0.0062 16.3 0.0 0.022 14.5 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain LexA_DNA_bind PF01726.16 AAG03922.1 - 0.045 13.5 0.0 0.18 11.6 0.0 2.0 1 1 0 1 1 1 0 LexA DNA binding domain HTH_10 PF04967.12 AAG03922.1 - 0.08 12.8 0.4 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_24 PF13412.6 AAG03922.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DAO PF01266.24 AAG03923.1 - 2e-53 182.2 5.0 2.4e-53 182.0 5.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG03923.1 - 8.4e-06 24.7 0.1 0.013 14.2 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 AAG03923.1 - 0.00027 20.1 4.3 0.00042 19.5 4.3 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAG03923.1 - 0.00029 21.0 1.3 0.00064 19.9 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAG03923.1 - 0.00035 19.9 0.5 0.00069 19.0 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 AAG03923.1 - 0.0016 17.8 0.0 0.3 10.3 0.1 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAG03923.1 - 0.0022 18.0 0.5 1.1 9.2 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 AAG03923.1 - 0.01 15.1 0.3 0.02 14.2 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 AAG03923.1 - 0.015 14.5 0.3 0.037 13.3 0.4 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAG03923.1 - 0.032 13.5 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 AAG03923.1 - 0.041 14.4 0.8 0.089 13.4 0.6 1.6 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG03923.1 - 0.092 12.1 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAG03923.1 - 0.12 11.4 0.2 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Cupin_2 PF07883.11 AAG03924.1 - 4.4e-15 55.1 0.0 6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 AAG03924.1 - 8.8e-11 41.7 0.0 1.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAG03924.1 - 4.8e-10 39.6 1.4 5.9e-10 39.3 0.4 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG03924.1 - 5.5e-07 29.5 0.0 8.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AAG03924.1 - 2.3e-05 24.3 0.0 3.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_26 PF13443.6 AAG03924.1 - 0.005 17.2 0.0 0.0084 16.5 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain CENP-C_C PF11699.8 AAG03924.1 - 0.033 14.4 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like HTH_35 PF13693.6 AAG03924.1 - 0.08 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TubC_N PF18563.1 AAG03924.1 - 0.14 12.1 0.2 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 TubC N-terminal docking domain TPM_phosphatase PF04536.14 AAG03925.1 - 4.1e-41 140.1 0.2 5.3e-41 139.7 0.2 1.1 1 0 0 1 1 1 1 TPM domain MOLO1 PF17175.4 AAG03925.1 - 0.07 13.3 0.1 0.32 11.1 0.1 1.9 1 1 0 1 1 1 0 Modulator of levamisole receptor-1 BCL9 PF11502.8 AAG03925.1 - 0.43 10.4 2.4 0.99 9.3 2.4 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein LemA PF04011.12 AAG03926.1 - 4.8e-57 192.0 0.5 5.6e-57 191.8 0.5 1.0 1 0 0 1 1 1 1 LemA family PaRep2b PF07775.11 AAG03926.1 - 0.055 12.0 0.1 0.076 11.5 0.1 1.2 1 0 0 1 1 1 0 PaRep2b protein TPR_6 PF13174.6 AAG03926.1 - 0.095 13.4 1.5 42 5.1 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat PG_binding_1 PF01471.18 AAG03926.1 - 0.25 11.6 3.7 14 6.0 0.0 2.8 2 1 0 2 2 2 0 Putative peptidoglycan binding domain DsbB PF02600.16 AAG03927.1 - 3e-34 118.6 12.2 3.4e-34 118.4 12.2 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB EamA PF00892.20 AAG03928.1 - 3.3e-15 56.5 31.0 5.7e-10 39.5 11.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 AAG03928.1 - 0.019 15.7 16.0 3 8.6 6.8 3.6 3 1 0 3 3 3 0 Small Multidrug Resistance protein MAPEG PF01124.18 AAG03929.1 - 6.6e-22 77.8 7.4 7.5e-22 77.6 7.4 1.0 1 0 0 1 1 1 1 MAPEG family Cytochrom_C_2 PF01322.20 AAG03930.1 - 8.6e-32 110.6 1.9 1.1e-31 110.2 1.9 1.1 1 0 0 1 1 1 1 Cytochrome C' DUF1090 PF06476.12 AAG03931.1 - 1.1e-34 118.8 8.1 1.5e-34 118.4 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1090) ABC_tran_CTD PF16326.5 AAG03931.1 - 0.0011 19.2 9.1 0.38 11.0 0.1 2.2 2 0 0 2 2 2 2 ABC transporter C-terminal domain DUF5446 PF17522.2 AAG03931.1 - 0.23 11.6 4.8 0.14 12.4 1.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5446) Spc7 PF08317.11 AAG03931.1 - 0.46 9.3 11.8 0.69 8.7 9.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein EMC3_TMCO1 PF01956.16 AAG03931.1 - 0.7 9.6 3.2 0.71 9.6 2.5 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Atg14 PF10186.9 AAG03931.1 - 1.9 7.5 7.7 2.3 7.2 7.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V-SNARE PF05008.15 AAG03931.1 - 2.2 8.7 9.2 0.9 10.0 2.4 2.4 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Esterase_phd PF10503.9 AAG03932.1 - 8e-16 58.2 1.4 1.2e-15 57.7 1.4 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.18 AAG03932.1 - 9.4e-08 31.9 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAG03932.1 - 4.3e-06 26.4 0.0 2.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 AAG03932.1 - 5.2e-05 23.0 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 AAG03932.1 - 5.6e-05 23.1 0.5 0.00036 20.4 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG03932.1 - 0.00019 22.1 10.0 0.00019 22.1 10.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 AAG03932.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 AAG03932.1 - 0.003 17.5 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 AAG03932.1 - 0.0049 17.0 0.2 0.012 15.8 0.2 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 AAG03932.1 - 0.014 15.1 0.1 0.039 13.6 0.1 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 AAG03932.1 - 0.031 13.2 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.12 AAG03932.1 - 0.039 12.6 0.1 0.069 11.8 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 AAG03932.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3426 PF11906.8 AAG03932.1 - 0.11 12.7 0.4 0.22 11.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Metallophos_2 PF12850.7 AAG03933.1 - 1.9e-11 44.4 0.4 6.2e-07 29.8 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAG03933.1 - 7.6e-10 39.6 1.7 1.4e-09 38.7 1.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Bowman-Birk_leg PF00228.20 AAG03933.1 - 1.9 9.0 3.4 15 6.1 0.5 2.5 2 0 0 2 2 2 0 Bowman-Birk serine protease inhibitor family Ferric_reduct PF01794.19 AAG03934.1 - 2e-19 69.9 4.0 2e-19 69.9 4.0 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 AAG03934.1 - 2e-08 34.3 0.0 5.5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 AAG03934.1 - 1.2e-06 29.1 0.0 2.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAG03934.1 - 4.9e-05 23.6 0.0 7.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AAG03934.1 - 0.0007 19.7 0.0 0.0081 16.3 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 AAG03934.1 - 0.035 14.6 9.3 0.59 10.7 1.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Cytochrom_B561 PF03188.16 AAG03934.1 - 0.041 14.0 2.1 0.18 11.9 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 S-AdoMet_synt_C PF02773.16 AAG03935.1 - 9.3e-67 223.3 0.0 1.8e-66 222.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AAG03935.1 - 1.8e-43 147.6 0.0 6.8e-43 145.7 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AAG03935.1 - 2.3e-40 137.3 0.5 4.5e-40 136.3 0.5 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Methyltransf_11 PF08241.12 AAG03936.1 - 4.6e-18 65.7 0.0 9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG03936.1 - 7.3e-18 64.9 0.0 1.2e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG03936.1 - 7.5e-18 64.8 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG03936.1 - 2.9e-17 63.2 0.1 7.2e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG03936.1 - 5.5e-14 52.7 0.1 1.6e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain HTH_20 PF12840.7 AAG03936.1 - 6.7e-12 45.3 3.9 1.1e-11 44.5 0.2 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain Ubie_methyltran PF01209.18 AAG03936.1 - 3.8e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HTH_5 PF01022.20 AAG03936.1 - 1.7e-08 34.2 0.1 8e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family CMAS PF02353.20 AAG03936.1 - 1.8e-05 24.2 0.0 2.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 AAG03936.1 - 0.00065 19.1 0.0 0.0009 18.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 AAG03936.1 - 0.00096 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 AAG03936.1 - 0.0011 18.2 0.0 0.0019 17.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 AAG03936.1 - 0.0027 17.5 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 AAG03936.1 - 0.006 16.2 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MarR_2 PF12802.7 AAG03936.1 - 0.013 15.4 0.1 0.013 15.4 0.1 3.0 4 0 0 4 4 4 0 MarR family MetW PF07021.12 AAG03936.1 - 0.019 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HTH_IclR PF09339.10 AAG03936.1 - 0.072 12.9 3.8 0.75 9.6 0.2 3.5 3 0 0 3 3 3 0 IclR helix-turn-helix domain Methyltransf_4 PF02390.17 AAG03936.1 - 0.18 11.2 0.0 0.41 10.1 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase Transketolase_N PF00456.21 AAG03937.1 - 7.6e-166 551.1 0.1 9.7e-166 550.7 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AAG03937.1 - 3.5e-46 157.1 0.0 9.1e-46 155.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAG03937.1 - 3.2e-16 59.3 0.0 9e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AAG03937.1 - 1.6e-07 30.8 0.0 0.0036 16.6 0.1 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AAG03937.1 - 1.1e-05 25.3 3.6 0.00023 21.0 0.6 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AAG03937.1 - 0.00064 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4632 PF15451.6 AAG03938.1 - 0.098 12.7 0.5 0.098 12.7 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4632) AP_endonuc_2 PF01261.24 AAG03939.1 - 8.6e-36 123.3 2.2 1.1e-35 123.0 2.2 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Gp_dh_C PF02800.20 AAG03940.1 - 2.7e-50 170.1 0.0 3.9e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AAG03940.1 - 3.9e-32 110.6 0.0 8.4e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AAG03940.1 - 4.7e-05 24.0 0.0 0.00019 22.1 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAG03940.1 - 0.035 14.9 0.0 0.25 12.2 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PGK PF00162.19 AAG03941.1 - 6.1e-140 466.4 1.4 7e-140 466.3 1.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase MliC PF09864.9 AAG03943.1 - 1e-12 47.8 0.0 1.3e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme F_bP_aldolase PF01116.20 AAG03944.1 - 5.6e-92 308.2 0.0 6.7e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF285 PF03382.14 AAG03944.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 SnoaL_3 PF13474.6 AAG03946.1 - 2.3e-18 66.6 0.0 2.9e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 AAG03946.1 - 1.1e-09 38.8 0.3 1e-07 32.5 0.1 2.2 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 AAG03946.1 - 1.2e-09 38.5 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.10 AAG03946.1 - 0.00025 21.2 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_4 PF13577.6 AAG03946.1 - 0.0012 19.0 0.2 0.002 18.2 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain CCD48 PF15799.5 AAG03946.1 - 0.034 12.5 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Methyltransf_11 PF08241.12 AAG03947.1 - 1.8e-16 60.6 0.1 4.3e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG03947.1 - 9.5e-14 51.9 0.1 1.9e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG03947.1 - 4.4e-06 27.4 0.0 7.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG03947.1 - 3e-05 23.9 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG03947.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAG03947.1 - 0.0029 17.7 0.0 0.0041 17.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_PK PF05891.12 AAG03947.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CoA_transf_3 PF02515.17 AAG03947.1 - 0.053 12.6 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 CoA-transferase family III Methyltransf_33 PF10017.9 AAG03947.1 - 0.072 12.2 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DREV PF05219.12 AAG03947.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 AAG03947.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 AAG03947.1 - 0.13 11.8 0.1 0.5 9.9 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DUF1949 PF09186.11 AAG03947.1 - 0.14 12.0 0.4 5.4 7.0 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1949) Methyltransf_29 PF03141.16 AAG03947.1 - 0.14 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 AAG03947.1 - 0.26 10.6 0.0 0.46 9.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HI0933_like PF03486.14 AAG03948.1 - 3.2e-151 503.7 0.0 3.6e-151 503.5 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AAG03948.1 - 2.2e-14 53.4 0.5 1.3e-09 37.7 0.5 2.6 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 AAG03948.1 - 1.6e-09 37.8 0.7 0.0003 20.5 0.4 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAG03948.1 - 1.8e-09 37.3 0.1 0.00038 19.8 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG03948.1 - 1.9e-07 30.8 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAG03948.1 - 1.2e-06 28.0 0.1 5.7e-06 25.8 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG03948.1 - 1.5e-05 25.2 1.8 1.5e-05 25.2 1.8 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAG03948.1 - 2.1e-05 23.9 0.6 0.00017 20.9 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AAG03948.1 - 4.1e-05 24.1 0.6 0.013 16.0 0.3 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAG03948.1 - 0.00014 21.1 0.5 0.0013 17.9 0.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AAG03948.1 - 0.00037 19.8 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AAG03948.1 - 0.0012 18.1 5.3 0.038 13.1 2.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 AAG03948.1 - 0.0023 17.2 0.1 0.0055 16.0 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 AAG03948.1 - 0.09 12.0 1.6 1.3 8.2 0.0 3.1 3 1 1 4 4 4 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 AAG03948.1 - 0.093 12.7 0.2 0.67 9.9 0.1 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 AAG03948.1 - 0.34 10.8 1.3 0.58 10.0 1.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF45 PF01863.17 AAG03949.1 - 8.5e-13 48.8 0.7 1.2e-12 48.3 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AAG03949.1 - 2.6e-05 24.4 3.2 2.8e-05 24.3 1.7 1.7 1 1 1 2 2 2 1 WLM domain HAD_2 PF13419.6 AAG03951.1 - 4.5e-23 82.2 0.0 5.5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG03951.1 - 5e-12 46.5 0.1 2.9e-10 40.8 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG03951.1 - 4e-07 30.0 0.0 7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAG03951.1 - 1.2e-05 25.8 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAG03951.1 - 0.024 14.7 0.0 0.36 11.0 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF805 PF05656.14 AAG03952.1 - 9.5e-33 112.8 0.3 1.1e-32 112.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF805) 7TMR-DISM_7TM PF07695.11 AAG03952.1 - 0.0035 17.3 0.7 0.0042 17.0 0.7 1.0 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF3792 PF12670.7 AAG03952.1 - 0.0043 17.2 1.2 0.0056 16.8 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) DUF2207 PF09972.9 AAG03952.1 - 0.0051 15.7 0.5 0.0069 15.2 0.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SecE PF00584.20 AAG03952.1 - 0.033 14.1 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF5353 PF17304.2 AAG03952.1 - 0.75 9.6 2.8 2.6 7.8 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5353) TMEM208_SND2 PF05620.11 AAG03952.1 - 0.79 9.5 4.8 0.25 11.1 0.7 1.9 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 AraC_binding PF02311.19 AAG03953.1 - 2.6e-37 127.8 2.8 4e-37 127.2 0.3 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.7 AAG03953.1 - 1e-34 119.9 1.5 1.8e-34 119.1 1.5 1.4 1 0 0 1 1 1 1 Cupin HTH_18 PF12833.7 AAG03953.1 - 7e-22 77.5 4.4 1.3e-21 76.6 2.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG03953.1 - 2.1e-16 59.6 0.1 1.5e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG03953.1 - 1e-07 31.5 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain TetR_N PF00440.23 AAG03953.1 - 0.012 15.4 0.4 0.086 12.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Nop52 PF05997.12 AAG03953.1 - 0.069 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleolar protein,Nop52 GMC_oxred_N PF00732.19 AAG03953.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Cupin_1 PF00190.22 AAG03953.1 - 0.24 11.0 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 Cupin CMD PF02627.20 AAG03954.1 - 1.5e-19 69.8 5.4 1.5e-19 69.8 5.4 1.4 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PG_binding_3 PF09374.10 AAG03954.1 - 0.018 15.3 0.1 0.039 14.2 0.1 1.5 1 1 0 1 1 1 0 Predicted Peptidoglycan domain Wzy_C PF04932.15 AAG03955.1 - 1.1 8.8 8.4 4 7.0 1.4 2.3 2 0 0 2 2 2 0 O-Antigen ligase Pmp3 PF01679.17 AAG03956.1 - 2.4e-22 78.8 9.0 2.6e-22 78.7 9.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SMI1_KNR4 PF09346.10 AAG03959.1 - 4.2e-06 27.2 0.0 1.1e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 AAG03959.1 - 0.0048 17.3 0.0 0.06 13.8 0.0 2.0 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall DUF4375 PF14300.6 AAG03960.1 - 1.4e-26 93.1 0.0 2.1e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4375) IMPa_N_2 PF18650.1 AAG03961.1 - 8.7e-61 204.7 0.1 1.7e-60 203.7 0.1 1.5 1 0 0 1 1 1 1 Immunomodulating metalloprotease N-terminal domain IMPa_helical PF18642.1 AAG03961.1 - 3.9e-28 98.0 0.0 9.1e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Immunomodulating metalloprotease helical domain Peptidase_M60 PF13402.6 AAG03961.1 - 5.2e-08 32.7 0.3 2.3e-07 30.6 0.3 2.0 1 1 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 AAG03961.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases DUF3712 PF12505.8 AAG03961.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) NERD PF08378.11 AAG03962.1 - 2.6e-10 40.7 0.0 3.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Nuclease-related domain DUF4172 PF13776.6 AAG03963.1 - 6.9e-33 112.8 0.2 2.1e-32 111.3 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4172) Fic PF02661.18 AAG03963.1 - 1e-15 58.4 0.0 2.7e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family MarR_2 PF12802.7 AAG03963.1 - 0.00041 20.2 0.6 0.0011 18.8 0.1 2.1 2 0 0 2 2 2 1 MarR family LexA_DNA_bind PF01726.16 AAG03963.1 - 0.0049 16.6 0.1 0.014 15.1 0.1 1.9 1 1 0 1 1 1 1 LexA DNA binding domain MarR PF01047.22 AAG03963.1 - 0.011 15.7 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 AAG03963.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB EAL PF00563.20 AAG03964.1 - 4.7e-77 258.7 0.0 8.4e-77 257.9 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG03964.1 - 3e-54 183.1 0.0 7.2e-54 181.9 0.0 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAG03964.1 - 6.4e-42 142.0 0.0 7.8e-16 58.2 0.0 4.8 5 0 0 5 5 5 4 PAS domain PAS PF00989.25 AAG03964.1 - 4.6e-38 129.7 0.4 7.6e-14 51.7 0.0 4.6 4 1 0 4 4 4 4 PAS fold SBP_bac_3 PF00497.20 AAG03964.1 - 2.8e-36 125.1 0.0 5.3e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PAS_8 PF13188.7 AAG03964.1 - 7.1e-29 99.3 0.0 3e-08 33.5 0.0 5.2 4 0 0 4 4 4 4 PAS domain PAS_4 PF08448.10 AAG03964.1 - 5.2e-25 87.8 3.3 6.4e-07 29.6 0.1 5.5 5 1 0 5 5 5 4 PAS fold PAS_3 PF08447.12 AAG03964.1 - 6.4e-23 80.9 0.4 3.1e-10 40.2 0.0 3.8 3 0 0 3 3 3 3 PAS fold DUF2721 PF11026.8 AAG03964.1 - 0.027 14.3 0.7 0.07 13.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) PAS_7 PF12860.7 AAG03964.1 - 0.028 14.6 0.0 0.33 11.1 0.0 2.9 3 0 0 3 3 3 0 PAS fold Autoind_bind PF03472.15 AAG03964.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Autoinducer binding domain Lig_chan-Glu_bd PF10613.9 AAG03964.1 - 0.14 12.4 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site CcmD PF04995.14 AAG03964.1 - 2.6 8.2 4.7 19 5.5 1.9 3.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Sigma70_ner PF04546.13 AAG03965.1 - 3.6e-65 219.7 0.3 3.6e-65 219.7 0.3 3.1 3 1 0 3 3 3 1 Sigma-70, non-essential region Sigma70_r1_1 PF03979.14 AAG03965.1 - 7.7e-30 102.8 1.2 7.7e-30 102.8 1.2 2.9 2 0 0 2 2 2 1 Sigma-70 factor, region 1.1 Sigma70_r3 PF04539.16 AAG03965.1 - 7.9e-30 102.8 0.9 7.9e-30 102.8 0.9 3.6 4 0 0 4 4 4 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 AAG03965.1 - 8.8e-22 76.7 0.3 1.8e-21 75.6 0.3 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG03965.1 - 2.8e-20 71.6 6.8 1e-18 66.5 0.8 3.4 3 0 0 3 3 3 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AAG03965.1 - 1.1e-13 50.9 2.1 4.8e-13 48.9 1.2 2.6 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 TMPIT PF07851.13 AAG03965.1 - 0.041 13.1 0.5 0.099 11.9 0.5 1.6 1 0 0 1 1 1 0 TMPIT-like protein RRN3 PF05327.11 AAG03965.1 - 0.35 9.4 1.7 0.77 8.2 1.7 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FliL PF03748.14 AAG03965.1 - 2.2 8.9 4.3 14 6.3 0.0 3.7 3 1 0 3 3 3 0 Flagellar basal body-associated protein FliL SlyX PF04102.12 AAG03965.1 - 7.7 7.2 7.9 1.2 9.8 0.6 3.4 4 0 0 4 4 4 0 SlyX Toprim_N PF08275.11 AAG03966.1 - 3.4e-43 146.7 0.0 5.8e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 AAG03966.1 - 5.4e-42 141.6 0.0 1.1e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 AAG03966.1 - 3.3e-23 82.6 7.5 3.3e-23 82.6 7.5 1.9 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding Toprim_4 PF13662.6 AAG03966.1 - 6.6e-18 65.0 0.0 1.2e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAG03966.1 - 1.3e-15 57.6 0.0 3e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 AAG03966.1 - 1.7e-10 41.1 0.0 5.9e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Toprim domain DnaB_bind PF10410.9 AAG03966.1 - 5.4e-09 36.1 0.1 1.8e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 DnaB-helicase binding domain of primase Toprim_3 PF13362.6 AAG03966.1 - 1.9e-07 31.3 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Toprim domain YqeY PF09424.10 AAG03967.1 - 3.6e-49 166.5 4.7 4.1e-49 166.4 4.7 1.0 1 0 0 1 1 1 1 Yqey-like protein Methyltransf_3 PF01596.17 AAG03967.1 - 0.034 13.3 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase Ribosomal_S21 PF01165.20 AAG03968.1 - 1.9e-22 78.7 5.6 1.9e-22 78.7 5.6 2.0 1 1 1 2 2 2 1 Ribosomal protein S21 Peptidase_M22 PF00814.25 AAG03969.1 - 3.5e-101 338.5 0.0 4e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 AAG03969.1 - 1.6e-05 24.7 0.0 0.00089 19.0 0.0 2.1 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus NBD_C PF17042.5 AAG03969.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain BcrAD_BadFG PF01869.20 AAG03969.1 - 0.15 11.5 0.0 0.71 9.3 0.0 1.9 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family G3P_acyltransf PF02660.15 AAG03970.1 - 3.5e-53 180.0 4.8 4e-53 179.8 4.8 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase FolB PF02152.18 AAG03971.1 - 5.2e-32 110.7 0.0 5.8e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase HPPK PF01288.20 AAG03972.1 - 3.1e-22 79.2 0.0 4.2e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PolyA_pol PF01743.20 AAG03973.1 - 1.8e-18 67.2 0.0 4e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AAG03973.1 - 4.6e-13 48.7 0.1 1.1e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 AAG03973.1 - 2.3e-08 34.3 1.4 9.8e-08 32.3 0.1 2.4 2 1 0 2 2 2 1 HD domain DUF4136 PF13590.6 AAG03974.1 - 5.7e-09 36.7 0.0 6.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) SpoVR PF04293.13 AAG03975.1 - 3.7e-177 589.2 2.7 4.3e-177 589.0 2.7 1.0 1 0 0 1 1 1 1 SpoVR like protein MCRS_N PF13325.6 AAG03975.1 - 0.048 13.7 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein DUF444 PF04285.12 AAG03976.1 - 4.8e-180 599.1 0.3 5.4e-180 599.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF444) VWA_2 PF13519.6 AAG03976.1 - 0.046 14.4 0.1 1.8 9.3 0.1 3.1 2 1 0 2 2 2 0 von Willebrand factor type A domain APG6_N PF17675.1 AAG03976.1 - 0.2 12.2 0.4 0.58 10.7 0.0 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region AAA_PrkA PF08298.11 AAG03977.1 - 1.2e-180 600.1 0.0 1.6e-180 599.7 0.0 1.1 1 0 0 1 1 1 1 PrkA AAA domain PrkA PF06798.12 AAG03977.1 - 3.9e-73 246.2 2.0 6.4e-73 245.5 2.0 1.3 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_22 PF13401.6 AAG03977.1 - 0.0074 16.6 0.0 0.048 13.9 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AAG03977.1 - 0.017 15.5 0.0 0.062 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 AAG03977.1 - 0.026 14.5 0.1 0.15 12.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NifW PF03206.14 AAG03977.1 - 0.09 13.3 0.2 0.29 11.7 0.2 1.8 1 0 0 1 1 1 0 Nitrogen fixation protein NifW TIP49 PF06068.13 AAG03977.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA PF00004.29 AAG03977.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rhodanese PF00581.20 AAG03978.1 - 1.3e-16 61.1 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain MMPL PF03176.15 AAG03978.1 - 0.073 12.0 0.1 0.087 11.7 0.1 1.0 1 0 0 1 1 1 0 MMPL family Metallophos PF00149.28 AAG03979.1 - 1e-13 52.3 0.0 1.4e-13 51.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAG03979.1 - 0.00011 22.4 0.0 0.00017 21.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 AAG03979.1 - 0.043 12.1 0.0 0.059 11.7 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase DUF2330 PF10092.9 AAG03979.1 - 0.16 11.0 0.0 1.3 8.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2330) DUF525 PF04379.14 AAG03980.1 - 3.8e-36 123.2 0.0 4.6e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 ApaG domain RrnaAD PF00398.20 AAG03981.1 - 3.1e-64 216.6 0.0 3.5e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 AAG03981.1 - 0.0022 17.9 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AAG03981.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_25 PF13649.6 AAG03981.1 - 0.052 14.3 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RsmJ PF04378.13 AAG03981.1 - 0.15 11.3 0.0 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Methyltransf_28 PF02636.17 AAG03981.1 - 0.21 11.2 0.1 0.47 10.0 0.1 1.6 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PdxA PF04166.12 AAG03982.1 - 2e-109 365.4 0.0 2.3e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Rotamase PF00639.21 AAG03983.1 - 3.2e-49 165.8 0.0 5.4e-27 94.6 0.0 2.6 2 0 0 2 2 2 2 PPIC-type PPIASE domain SurA_N PF09312.11 AAG03983.1 - 4e-46 155.9 5.7 9.9e-46 154.7 5.7 1.7 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase_3 PF13616.6 AAG03983.1 - 7.2e-46 155.5 0.0 1.9e-28 99.3 0.0 2.3 1 1 1 2 2 2 2 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAG03983.1 - 1.6e-20 74.1 0.0 1.7e-10 41.8 0.0 2.8 1 1 2 3 3 3 2 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AAG03983.1 - 1.7e-13 50.7 2.8 1.7e-13 50.7 2.8 2.7 2 1 1 3 3 3 1 SurA N-terminal domain SurA_N_2 PF13623.6 AAG03983.1 - 1.6e-07 31.3 1.2 1.6e-07 31.3 1.2 2.7 2 1 1 3 3 3 1 SurA N-terminal domain Trigger_C PF05698.14 AAG03983.1 - 0.00012 22.1 8.4 0.00014 21.9 0.8 3.5 1 1 2 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus LptD PF04453.14 AAG03984.1 - 1.5e-119 399.7 20.2 3.2e-119 398.6 20.2 1.6 1 0 0 1 1 1 1 LPS transport system D OstA PF03968.14 AAG03984.1 - 3.2e-11 43.4 0.4 6.8e-11 42.4 0.4 1.6 1 0 0 1 1 1 1 OstA-like protein OstA_2 PF13100.6 AAG03984.1 - 0.041 13.5 0.8 0.097 12.3 0.1 2.0 2 0 0 2 2 2 0 OstA-like protein APH PF01636.23 AAG03985.1 - 1.8e-35 123.0 5.1 1.8e-35 123.0 5.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family NTP_transferase PF00483.23 AAG03986.1 - 2.2e-19 70.0 0.0 8e-16 58.4 0.0 2.0 2 0 0 2 2 2 2 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAG03986.1 - 3.2e-12 47.1 0.1 4.6e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAG03986.1 - 0.0049 16.6 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DnaJ PF00226.31 AAG03987.1 - 1.6e-08 34.5 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TerB PF05099.13 AAG03987.1 - 0.0071 16.3 0.4 0.015 15.3 0.4 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TerB DUF1192 PF06698.11 AAG03987.1 - 0.12 12.4 4.2 0.2 11.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF3530 PF12048.8 AAG03988.1 - 1.2e-106 356.7 10.5 1.6e-106 356.3 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Hydrolase_4 PF12146.8 AAG03988.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 AAG03988.1 - 0.0033 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase His_Phos_1 PF00300.22 AAG03988.1 - 0.14 11.8 1.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) GEN1_C PF18380.1 AAG03988.1 - 1.2 10.1 4.9 5.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Med3 PF11593.8 AAG03988.1 - 5.3 6.1 6.8 8.2 5.5 6.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SBP_bac_3 PF00497.20 AAG03989.1 - 8.8e-27 94.0 0.0 1.3e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PAS_3 PF08447.12 AAG03989.1 - 1.6e-21 76.4 1.8 2.8e-15 56.4 0.3 3.0 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AAG03989.1 - 1.3e-14 54.4 4.0 5.7e-11 42.7 0.1 4.2 4 0 0 4 4 4 2 PAS fold HisKA_3 PF07730.13 AAG03989.1 - 5.8e-14 52.4 0.5 5.8e-14 52.4 0.5 3.2 3 0 0 3 3 3 1 Histidine kinase HATPase_c PF02518.26 AAG03989.1 - 2.7e-11 44.0 0.0 6.7e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AAG03989.1 - 3e-11 43.5 0.0 1.7e-07 31.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAG03989.1 - 1.4e-10 41.2 0.0 1.3e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAG03989.1 - 1.2e-06 28.4 0.1 4.7e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAG03989.1 - 2.1e-06 27.7 0.0 6.3e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Phosphonate-bd PF12974.7 AAG03989.1 - 0.006 16.2 0.2 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein AAA_33 PF13671.6 AAG03989.1 - 0.15 12.2 0.5 1.9 8.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain DMPK_coil PF08826.10 AAG03989.1 - 2.7 8.2 7.0 5.3 7.2 2.3 3.4 3 1 0 3 3 3 0 DMPK coiled coil domain like Response_reg PF00072.24 AAG03990.1 - 3.2e-27 94.9 0.0 4.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG03990.1 - 1.1e-19 69.7 0.3 1.8e-19 69.0 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AAG03990.1 - 0.00022 20.7 0.1 0.00053 19.5 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAG03990.1 - 0.0018 17.9 0.1 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Cadherin_2 PF08266.12 AAG03990.1 - 0.016 15.0 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Cadherin-like HTH_40 PF14493.6 AAG03990.1 - 0.018 15.5 0.1 0.035 14.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AAG03990.1 - 0.04 13.9 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AAG03990.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAG03990.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 HTH domain KORA PF16509.5 AAG03990.1 - 0.063 13.6 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_Tnp_ISL3 PF13542.6 AAG03990.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AAG03990.1 - 0.12 12.5 0.6 0.38 10.9 0.0 2.3 3 1 0 3 3 2 0 Helix-turn-helix domain HTH_10 PF04967.12 AAG03990.1 - 0.15 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_29 PF13551.6 AAG03990.1 - 0.16 12.0 0.6 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix SBP_bac_8 PF13416.6 AAG03991.1 - 7.6e-43 147.3 0.4 1e-42 146.9 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03991.1 - 7.2e-11 42.0 1.0 1.7e-10 40.7 1.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03991.1 - 1.3e-06 28.6 4.2 1.8e-06 28.1 4.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ABC_tran PF00005.27 AAG03992.1 - 4.5e-34 117.9 0.0 7.9e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAG03992.1 - 4.5e-17 62.0 0.2 4.5e-17 62.0 0.2 2.6 3 1 1 4 4 4 1 TOBE domain SMC_N PF02463.19 AAG03992.1 - 0.00085 18.8 0.0 0.027 13.9 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain TOBE PF03459.17 AAG03992.1 - 0.0033 17.7 0.0 3 8.2 0.0 3.0 2 0 0 2 2 2 2 TOBE domain DUF1513 PF07433.11 AAG03992.1 - 0.0072 15.4 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) Pox_L5 PF04872.13 AAG03992.1 - 0.0076 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Poxvirus L5 protein family AAA_25 PF13481.6 AAG03992.1 - 0.01 15.4 0.1 0.099 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAG03992.1 - 0.013 15.8 0.3 0.036 14.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAG03992.1 - 0.059 13.1 0.0 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.16 AAG03992.1 - 0.097 12.1 0.2 12 5.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 AAG03992.1 - 0.1 12.9 0.0 0.27 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 AAG03992.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain FeoB_N PF02421.18 AAG03992.1 - 0.13 11.8 0.5 0.36 10.3 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.6 AAG03992.1 - 0.16 11.7 0.1 8.5 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SBP_bac_8 PF13416.6 AAG03993.1 - 2.6e-46 158.7 6.2 3.6e-46 158.2 6.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG03993.1 - 1.7e-14 53.8 1.1 2.9e-14 53.1 1.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG03993.1 - 4.9e-10 39.9 9.4 7e-10 39.4 9.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 AAG03994.1 - 3.6e-10 39.9 22.5 3.6e-10 39.9 22.5 2.4 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG03995.1 - 3.7e-19 69.2 21.7 3.7e-19 69.2 21.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ribul_P_3_epim PF00834.19 AAG03996.1 - 3.6e-89 297.4 0.0 4.2e-89 297.2 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AAG03996.1 - 7.8e-07 29.0 0.0 0.00056 19.7 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 AAG03996.1 - 0.0083 15.6 0.1 0.017 14.6 0.0 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein TMP-TENI PF02581.17 AAG03996.1 - 0.083 12.2 0.0 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase HAD_2 PF13419.6 AAG03997.1 - 6e-36 124.2 0.0 7.3e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG03997.1 - 2.2e-26 93.5 0.0 2.8e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG03997.1 - 1.7e-16 61.2 0.0 2.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG03997.1 - 1.5e-11 44.2 0.0 2.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 AAG03997.1 - 6.3e-06 26.1 0.0 0.13 11.9 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAG03997.1 - 4.5e-05 23.5 0.1 0.00059 19.9 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 AAG03997.1 - 0.015 15.2 0.0 1.2 8.9 0.1 2.9 2 1 0 2 2 2 0 Acid Phosphatase S6PP PF05116.13 AAG03997.1 - 0.015 14.8 0.1 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.12 AAG03997.1 - 0.026 13.9 0.0 11 5.4 0.0 2.9 3 0 0 3 3 3 0 Putative Phosphatase COPI_C PF06957.11 AAG03997.1 - 0.044 12.6 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Acid_phosphat_B PF03767.14 AAG03997.1 - 0.13 11.9 0.0 14 5.2 0.0 2.8 2 1 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Chorismate_bind PF00425.18 AAG03998.1 - 1.9e-97 325.8 0.0 2.8e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AAG03998.1 - 5.9e-35 120.5 0.0 1.3e-32 113.0 0.0 2.8 2 1 1 3 3 3 2 Anthranilate synthase component I, N terminal region PyocinActivator PF11112.8 AAG03999.1 - 3.3e-29 100.8 0.0 3.9e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Pyocin activator protein PrtN HTH_3 PF01381.22 AAG04000.1 - 1.8e-11 43.9 0.1 3.4e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix Peptidase_S24 PF00717.23 AAG04000.1 - 2.5e-11 43.3 0.0 3.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HTH_19 PF12844.7 AAG04000.1 - 3.3e-09 36.6 0.0 2.3e-08 33.9 0.0 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_31 PF13560.6 AAG04000.1 - 1.1e-08 35.3 1.2 5.3e-08 33.1 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 AAG04000.1 - 3.5e-08 33.7 0.1 7.2e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Phage_CI_repr PF07022.13 AAG04000.1 - 0.00096 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain YdaS_antitoxin PF15943.5 AAG04000.1 - 0.0021 17.9 0.1 0.0048 16.7 0.1 1.6 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_37 PF13744.6 AAG04000.1 - 0.0051 16.8 0.6 0.0091 15.9 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_CI_C PF16452.5 AAG04000.1 - 0.0075 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage CI repressor C-terminal domain TetR_N PF00440.23 AAG04000.1 - 0.1 12.4 0.9 1.3 8.9 0.1 2.6 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family HTH_10 PF04967.12 AAG04000.1 - 0.15 11.9 0.1 6.4 6.7 0.1 2.4 2 0 0 2 2 2 0 HTH DNA binding domain HTH_AsnC-type PF13404.6 AAG04000.1 - 0.16 11.8 0.1 13 5.7 0.0 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain zf-dskA_traR PF01258.17 AAG04001.1 - 1e-13 50.9 10.0 1.5e-13 50.5 10.0 1.2 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger HicA_toxin PF07927.12 AAG04002.1 - 0.048 13.7 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, DUF1492 PF07374.11 AAG04002.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Phage_holin_3_5 PF16085.5 AAG04003.1 - 7.7e-63 209.7 7.7 9e-63 209.5 7.7 1.0 1 0 0 1 1 1 1 Bacteriophage holin Hol, superfamily III Phage_holin_3_3 PF16083.5 AAG04003.1 - 2.9e-07 30.5 13.7 3.6e-07 30.2 13.7 1.1 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III LapA_dom PF06305.11 AAG04003.1 - 3.8 7.4 8.5 2.3 8.1 0.3 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Phage_base_V PF04717.12 AAG04005.1 - 5.7e-45 151.8 0.2 1.2e-44 150.8 0.0 1.6 2 0 0 2 2 2 1 Type VI secretion system, phage-baseplate injector GPW_gp25 PF04965.14 AAG04006.1 - 1.7e-15 56.5 0.0 1.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Baseplate_J PF04865.14 AAG04007.1 - 1.8e-23 83.0 0.2 3.3e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Baseplate J-like protein Tail_P2_I PF09684.10 AAG04008.1 - 7.6e-42 142.5 0.0 9.1e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) DUF3751 PF12571.8 AAG04009.1 - 2.8e-47 160.6 0.0 7.9e-47 159.1 0.0 1.7 2 0 0 2 2 2 1 Phage tail-collar fibre protein Phage_tail_APC PF16778.5 AAG04010.1 - 6e-08 32.4 0.8 1.5e-07 31.2 0.4 1.8 2 0 0 2 2 2 1 Phage tail assembly chaperone protein Caudo_TAP PF02413.17 AAG04010.1 - 0.0029 17.8 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Phage_sheath_1 PF04984.14 AAG04011.1 - 2.9e-33 115.1 0.9 3.4e-33 114.9 0.2 1.5 2 0 0 2 2 2 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 AAG04011.1 - 1.6e-21 76.2 0.0 2.9e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 Phage tail sheath C-terminal domain Phage_tube PF04985.14 AAG04012.1 - 7.2e-59 198.2 0.0 8e-59 198.0 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein FII Phage_TAC_7 PF10109.9 AAG04013.1 - 4e-18 65.3 0.1 4.7e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 Allantoicase PF03561.15 AAG04013.1 - 0.2 11.6 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Allantoicase repeat Coiled PF05710.12 AAG04014.1 - 0.1 13.4 2.7 0.3 11.9 2.7 1.8 1 0 0 1 1 1 0 Coiled coil Phage_P2_GpU PF06995.11 AAG04015.1 - 7.6e-40 135.3 0.0 1.2e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Phage P2 GpU HHH PF00633.23 AAG04015.1 - 0.016 15.0 0.0 0.055 13.4 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_3 PF12836.7 AAG04015.1 - 0.04 14.2 0.1 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif TSKS PF15358.6 AAG04015.1 - 0.059 11.7 0.2 0.082 11.3 0.2 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate COG2 PF06148.11 AAG04015.1 - 0.1 12.7 0.0 1.5 8.9 0.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HisKA_3 PF07730.13 AAG04015.1 - 0.16 12.5 2.2 10 6.7 0.0 3.3 2 1 2 4 4 4 0 Histidine kinase Phage_tail_X PF05489.12 AAG04016.1 - 6.6e-26 89.8 0.0 7.5e-26 89.6 0.0 1.0 1 0 0 1 1 1 1 Phage Tail Protein X Phage_GPD PF05954.11 AAG04017.1 - 1.2e-21 77.4 0.0 1.4e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Phage-tail_3 PF13550.6 AAG04017.1 - 0.032 14.1 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative phage tail protein Glyco_hydro_19 PF00182.19 AAG04018.1 - 3e-05 24.0 0.1 0.00032 20.7 0.0 2.1 1 1 1 2 2 2 1 Chitinase class I Phage_TTP_11 PF16460.5 AAG04022.1 - 7.4e-84 278.5 0.1 8.6e-84 278.3 0.1 1.0 1 0 0 1 1 1 1 Phage tail tube, TTP, lambda-like Phage_TTP_12 PF16461.5 AAG04022.1 - 9.2e-05 22.1 0.0 0.0073 16.0 0.0 2.1 2 0 0 2 2 2 2 Lambda phage tail tube protein, TTP Phage_TAC_13 PF16459.5 AAG04023.1 - 1.6e-21 76.6 0.0 1.8e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Phage tail assembly chaperone, TAC TC1 PF15063.6 AAG04023.1 - 0.046 13.6 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 Dioxygenase_N PF04444.14 AAG04024.1 - 0.053 13.4 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Tape_meas_lam_C PF09718.10 AAG04025.1 - 2.8e-54 181.2 17.6 1.7e-24 85.7 6.4 4.2 3 0 0 3 3 3 3 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Lipoprotein_X PF03305.13 AAG04025.1 - 0.074 12.8 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Mycoplasma MG185/MG260 protein FAA_hydrolase_N PF09298.11 AAG04025.1 - 0.096 12.9 1.5 4.4 7.5 0.5 2.5 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal HA PF03457.14 AAG04025.1 - 0.12 12.7 1.3 20 5.6 0.0 3.0 3 0 0 3 3 3 0 Helicase associated domain Phage_min_tail PF05939.13 AAG04026.1 - 7.5e-32 109.9 0.0 8.3e-32 109.8 0.0 1.0 1 0 0 1 1 1 1 Phage minor tail protein Phage_tail_L PF05100.12 AAG04027.1 - 1e-96 322.1 0.0 1.2e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 Phage minor tail protein L NLPC_P60 PF00877.19 AAG04028.1 - 5.9e-20 71.3 0.0 1.2e-19 70.2 0.0 1.5 1 1 0 1 1 1 1 NlpC/P60 family Prok-JAB PF14464.6 AAG04028.1 - 1.2e-18 67.0 3.3 1.9e-18 66.4 3.3 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Lambda_tail_I PF06805.12 AAG04029.1 - 0.00033 20.9 0.0 0.00084 19.6 0.0 1.7 1 0 0 1 1 1 1 Bacteriophage lambda tail assembly protein I Halogen_Hydrol PF10112.9 AAG04029.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SseC PF04888.12 AAG04029.1 - 1.4 8.5 2.9 2.3 7.7 2.9 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Phage-tail_3 PF13550.6 AAG04030.1 - 5.4e-26 91.4 0.1 5.4e-26 91.4 0.1 3.1 3 1 0 3 3 3 1 Putative phage tail protein DUF1983 PF09327.11 AAG04030.1 - 7.5e-24 83.6 3.0 2.7e-23 81.9 3.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1983) Phage_GPD PF05954.11 AAG04030.1 - 0.00059 19.2 0.2 0.00059 19.2 0.2 2.3 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) DUF1664 PF07889.12 AAG04030.1 - 0.05 13.6 1.6 0.097 12.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Transthyretin PF00576.21 AAG04030.1 - 3.7 8.3 4.3 31 5.3 0.1 3.2 3 0 0 3 3 3 0 HIUase/Transthyretin family NAGLU_N PF12971.7 AAG04032.1 - 0.072 12.9 0.1 0.69 9.7 0.0 2.4 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain HHH_3 PF12836.7 AAG04034.1 - 0.066 13.5 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4790 PF16037.5 AAG04034.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) GATase PF00117.28 AAG04038.1 - 1.6e-55 187.9 0.0 1.7e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAG04038.1 - 1.4e-10 41.3 0.4 3e-10 40.2 0.4 1.5 1 1 0 1 1 1 1 Peptidase C26 Glycos_transf_3 PF00591.21 AAG04039.1 - 1e-101 339.8 1.9 1e-101 339.8 1.9 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AAG04039.1 - 4.5e-19 68.0 1.5 4.5e-19 68.0 1.5 2.5 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DUF2521 PF10730.9 AAG04039.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) IGPS PF00218.21 AAG04040.1 - 4.3e-101 337.4 0.1 4.9e-101 337.2 0.1 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase cNMP_binding PF00027.29 AAG04041.1 - 1.5e-22 79.4 0.1 2.6e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAG04041.1 - 5.3e-13 48.7 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAG04041.1 - 1.4e-11 43.8 0.2 3.4e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family TrmB PF01978.19 AAG04041.1 - 0.00061 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AAG04041.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 AAG04041.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 AAG04041.1 - 0.0027 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AAG04041.1 - 0.01 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 AAG04041.1 - 0.022 14.9 0.1 0.093 12.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MltA PF03562.17 AAG04041.1 - 0.037 13.8 0.0 0.087 12.6 0.0 1.6 2 0 0 2 2 2 0 MltA specific insert domain GntR PF00392.21 AAG04041.1 - 0.05 13.3 0.1 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 AAG04041.1 - 0.051 14.1 0.3 4.7 7.8 0.0 3.4 3 0 0 3 3 3 0 Winged helix DNA-binding domain Rrf2 PF02082.20 AAG04041.1 - 0.098 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator SgrR_N PF12793.7 AAG04041.1 - 0.11 12.7 0.0 0.55 10.5 0.0 2.0 1 1 1 2 2 2 0 Sugar transport-related sRNA regulator N-term HTH_24 PF13412.6 AAG04041.1 - 0.12 12.0 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding OsmC PF02566.19 AAG04042.1 - 2.4e-19 69.6 0.0 3e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein AdoMet_dc PF02675.15 AAG04043.1 - 6e-32 110.1 0.0 1.2e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase COQ7 PF03232.13 AAG04044.1 - 2.1e-39 135.0 0.1 2.4e-39 134.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 AAG04044.1 - 1.4e-06 28.8 0.0 2.5e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 AAG04044.1 - 0.00032 20.6 0.2 0.00062 19.7 0.2 1.4 1 1 0 1 1 1 1 Ferritin-like domain HIT PF01230.23 AAG04045.1 - 8.2e-26 90.6 0.2 9.3e-26 90.4 0.2 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AAG04045.1 - 5.2e-24 84.9 0.1 6e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.29 AAG04046.1 - 2e-27 96.2 0.0 5.1e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AAG04046.1 - 1.9e-05 24.3 0.2 6e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 AAG04046.1 - 0.014 14.6 0.0 0.059 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 AAG04046.1 - 0.22 10.8 0.2 0.45 9.8 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin adh_short PF00106.25 AAG04047.1 - 1.1e-46 158.8 0.0 1.3e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG04047.1 - 3.1e-31 108.7 0.0 4e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG04047.1 - 5e-12 46.1 0.1 8.6e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG04047.1 - 0.00019 21.0 0.0 0.0003 20.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 AAG04047.1 - 0.0012 18.9 0.2 0.32 11.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAG04047.1 - 0.0041 17.6 11.0 0.02 15.4 0.1 3.4 2 2 1 3 3 3 1 Glycosyl transferase 4-like domain Eno-Rase_NADH_b PF12242.8 AAG04047.1 - 0.046 13.5 0.1 0.099 12.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2492 PF10678.9 AAG04047.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) Dynactin PF12455.8 AAG04047.1 - 0.061 12.6 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Dynein associated protein Glyco_trans_4_2 PF13477.6 AAG04047.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like ETF PF01012.21 AAG04047.1 - 0.14 12.0 0.1 1.9 8.3 0.1 2.3 2 0 0 2 2 2 0 Electron transfer flavoprotein domain PAC4 PF16093.5 AAG04047.1 - 0.16 12.2 0.2 15 5.9 0.0 2.5 1 1 1 2 2 2 0 Proteasome assembly chaperone 4 NAD_binding_10 PF13460.6 AAG04047.1 - 0.18 11.7 0.2 0.27 11.1 0.2 1.6 1 1 0 1 1 1 0 NAD(P)H-binding DFP PF04127.15 AAG04047.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF805 PF05656.14 AAG04048.1 - 6e-21 74.8 4.7 6e-21 74.8 4.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF805) zf-CHY PF05495.12 AAG04048.1 - 0.029 14.9 0.1 0.046 14.2 0.1 1.2 1 0 0 1 1 1 0 CHY zinc finger CpXC PF14353.6 AAG04048.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 CpXC protein tRNA-synt_1g PF09334.11 AAG04048.1 - 0.4 9.4 0.6 0.58 8.8 0.6 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) TF_Zn_Ribbon PF08271.12 AAG04048.1 - 1.7 8.2 3.9 9.9 5.8 3.9 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AAG04048.1 - 3.4 7.2 7.1 41 3.8 7.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AAG04048.1 - 4.6 7.1 5.6 22 4.9 5.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain NMO PF03060.15 AAG04049.1 - 1.8e-28 99.9 1.6 1.6e-27 96.8 0.6 2.0 1 1 1 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 AAG04049.1 - 5.7e-06 25.6 3.0 5.7e-06 25.6 3.0 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AAG04049.1 - 0.0017 17.5 1.0 0.56 9.2 0.9 2.7 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain UPF0093 PF03653.13 AAG04050.1 - 1.7e-56 190.5 8.2 1.9e-56 190.4 8.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) CopD PF05425.13 AAG04050.1 - 1.3e-06 28.7 5.5 1.3e-06 28.7 5.5 1.6 1 1 1 2 2 2 1 Copper resistance protein D DUF2269 PF10027.9 AAG04050.1 - 0.0002 21.5 10.5 0.00082 19.5 10.5 1.8 1 1 0 1 1 1 1 Predicted integral membrane protein (DUF2269) SirB PF04247.12 AAG04050.1 - 0.9 9.6 13.7 4.6 7.4 13.7 2.1 1 1 0 1 1 1 0 Invasion gene expression up-regulator, SirB Semialdhyde_dh PF01118.24 AAG04051.1 - 2.4e-38 131.3 0.0 4.1e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AAG04051.1 - 4.4e-17 62.8 0.0 6.7e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain F420_oxidored PF03807.17 AAG04051.1 - 0.00057 20.4 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 AAG04051.1 - 0.0013 19.6 0.0 0.0023 18.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 AAG04051.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADIP PF11559.8 AAG04052.1 - 0.001 19.2 1.4 0.0016 18.6 1.4 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding IFT20 PF14931.6 AAG04052.1 - 0.0065 16.6 4.5 0.0065 16.6 2.9 1.7 1 1 1 2 2 2 1 Intraflagellar transport complex B, subunit 20 DUF2968 PF11180.8 AAG04052.1 - 0.067 12.8 6.7 0.1 12.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Atg14 PF10186.9 AAG04052.1 - 0.18 10.9 1.5 0.26 10.3 1.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 POTRA PF07244.15 AAG04052.1 - 0.64 10.6 2.1 5.3 7.7 0.4 2.2 2 0 0 2 2 2 0 Surface antigen variable number repeat SlyX PF04102.12 AAG04052.1 - 5.3 7.7 8.7 14 6.4 0.8 2.8 1 1 1 2 2 2 0 SlyX Bactofilin PF04519.13 AAG04053.1 - 6.5e-25 87.3 2.3 7.8e-25 87.0 2.3 1.1 1 0 0 1 1 1 1 Polymer-forming cytoskeletal Fe-S_biosyn PF01521.20 AAG04054.1 - 2.7e-19 69.4 0.0 3.3e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis AnmK PF03702.14 AAG04055.1 - 1.2e-169 564.2 0.0 1.3e-169 564.1 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Peptidase_M23 PF01551.22 AAG04056.1 - 1.4e-32 111.8 2.8 1.4e-32 111.8 2.8 2.2 2 0 0 2 2 2 1 Peptidase family M23 OapA PF04225.12 AAG04056.1 - 1.6e-12 47.4 0.2 5.4e-11 42.5 0.1 2.7 2 1 0 2 2 2 1 Opacity-associated protein A LysM-like domain tRNA-synt_1b PF00579.25 AAG04057.1 - 7.7e-81 271.6 0.0 9.6e-81 271.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 AAG04057.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AAG04057.1 - 0.027 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 S4 domain HTH_50 PF18024.1 AAG04057.1 - 0.16 11.6 0.0 0.51 10.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DNA_pol3_alpha PF07733.12 AAG04058.1 - 9e-83 277.8 0.0 1.2e-82 277.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AAG04058.1 - 3.8e-58 195.5 0.0 5.9e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain HHH_6 PF14579.6 AAG04058.1 - 5.8e-22 77.7 0.1 1.3e-21 76.6 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif PHP PF02811.19 AAG04058.1 - 2.3e-18 67.0 0.0 4.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 PHP domain tRNA_anti-codon PF01336.25 AAG04058.1 - 3e-05 23.9 0.1 7.2e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Raf1_HTH PF18579.1 AAG04058.1 - 0.069 12.9 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain IMS PF00817.20 AAG04059.1 - 4.2e-06 26.8 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family SulA PF03846.14 AAG04060.1 - 0.00051 20.0 0.2 0.0007 19.5 0.2 1.1 1 0 0 1 1 1 1 Cell division inhibitor SulA RecA PF00154.21 AAG04060.1 - 0.031 13.7 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Amidohydro_2 PF04909.14 AAG04060.1 - 0.052 13.3 0.4 0.083 12.7 0.3 1.3 1 1 0 1 1 1 0 Amidohydrolase Heme_oxygenase PF01126.20 AAG04061.1 - 3.1e-35 121.8 0.1 5e-35 121.1 0.1 1.3 1 1 0 1 1 1 1 Heme oxygenase STN PF07660.14 AAG04063.1 - 2.5e-05 24.0 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain TonB_2 PF13103.6 AAG04063.1 - 3.6e-05 23.9 0.0 0.00011 22.3 0.0 1.7 2 0 0 2 2 2 1 TonB C terminal Sigma70_r4_2 PF08281.12 AAG04064.1 - 3.5e-14 52.2 1.2 1.3e-13 50.4 0.5 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG04064.1 - 7.1e-07 28.7 2.1 1.7e-06 27.4 0.5 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG04064.1 - 0.00012 21.8 0.5 0.00027 20.6 0.5 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 HTH_23 PF13384.6 AAG04064.1 - 0.0009 19.0 3.1 0.0015 18.3 0.9 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AAG04064.1 - 0.0018 18.2 2.3 0.0051 16.7 2.3 1.8 1 1 0 1 1 1 1 ECF sigma factor HTH_Tnp_ISL3 PF13542.6 AAG04064.1 - 0.0059 16.0 0.4 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 AAG04064.1 - 0.015 15.2 1.1 0.043 13.8 0.3 2.2 2 0 0 2 2 2 0 HTH domain HTH_28 PF13518.6 AAG04064.1 - 0.032 14.3 0.6 0.076 13.2 0.6 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 AAG04064.1 - 0.097 12.5 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_38 PF13936.6 AAG04064.1 - 1 9.2 5.3 0.19 11.5 1.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain FecR PF04773.13 AAG04065.1 - 1.9e-14 54.1 0.2 3.4e-14 53.2 0.2 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG04065.1 - 1.9e-11 43.6 3.6 1.9e-11 43.6 3.6 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) N_methyl PF07963.12 AAG04066.1 - 1.4e-10 40.3 1.1 2e-10 39.7 1.1 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSJ PF11612.8 AAG04066.1 - 3.9e-05 23.9 0.1 5.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J N_methyl PF07963.12 AAG04067.1 - 1.9e-10 39.9 0.5 2.8e-10 39.3 0.5 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif GspH PF12019.8 AAG04067.1 - 0.0001 22.7 0.1 0.00014 22.3 0.1 1.1 1 0 0 1 1 1 1 Type II transport protein GspH T2SSC PF11356.8 AAG04068.1 - 1.5e-08 34.6 1.8 6.2e-08 32.6 0.3 1.9 1 1 1 2 2 2 1 Type II secretion system protein C T2SSB PF16537.5 AAG04068.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system protein B T2SSI PF02501.17 AAG04069.1 - 5.9e-19 68.0 0.1 8.9e-19 67.4 0.1 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein I N_methyl PF07963.12 AAG04069.1 - 1e-09 37.6 4.0 1.9e-09 36.7 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSG PF08334.11 AAG04070.1 - 4.2e-40 136.2 0.1 5.1e-40 135.9 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AAG04070.1 - 1.4e-10 40.3 2.5 1.9e-10 39.8 2.5 1.2 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSK PF03934.13 AAG04071.1 - 1.5e-66 224.7 3.4 1.7e-66 224.4 3.4 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_3 PF12836.7 AAG04071.1 - 1.8e-05 24.9 0.0 0.013 15.7 0.0 3.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_6 PF14579.6 AAG04071.1 - 0.076 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif GspL_C PF12693.7 AAG04072.1 - 5.4e-46 156.3 0.7 5.4e-46 156.3 0.7 1.6 2 0 0 2 2 2 1 GspL periplasmic domain DUF3563 PF12086.8 AAG04072.1 - 0.12 12.1 0.8 0.5 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) T2SSM PF04612.12 AAG04073.1 - 4.6e-47 160.1 4.1 5.3e-47 159.8 4.1 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M DciA PF05258.12 AAG04073.1 - 1.1 9.8 3.8 5.2 7.5 0.3 2.7 1 1 2 3 3 3 0 Dna[CI] antecedent, DciA Secretin PF00263.21 AAG04074.1 - 3.1e-49 166.9 0.6 5.4e-49 166.1 0.6 1.4 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAG04074.1 - 1.3e-36 124.9 32.4 3.6e-12 46.5 0.6 4.6 3 1 0 3 3 3 3 Bacterial type II/III secretion system short domain T2SSE PF00437.20 AAG04075.1 - 1.2e-85 286.9 4.5 1.6e-85 286.5 4.5 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AAG04075.1 - 0.00024 21.5 0.3 0.001 19.5 0.0 2.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAG04075.1 - 0.0004 20.7 0.0 0.0013 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AAG04075.1 - 0.00072 19.6 0.1 0.0015 18.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAG04075.1 - 0.00091 19.7 0.1 0.0033 17.8 0.0 2.0 2 1 1 3 3 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AAG04075.1 - 0.0012 18.8 1.6 0.38 10.7 0.2 2.4 1 1 1 2 2 2 2 NTPase AAA_18 PF13238.6 AAG04075.1 - 0.0015 19.0 0.0 0.003 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG04075.1 - 0.0016 18.1 0.1 0.0038 16.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG04075.1 - 0.0038 17.8 0.0 0.0064 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AAG04075.1 - 0.0041 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG04075.1 - 0.0052 16.5 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAG04075.1 - 0.0079 16.5 1.5 0.023 15.0 0.1 2.5 4 0 0 4 4 3 1 AAA domain Rad17 PF03215.15 AAG04075.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 AAG04075.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAG04075.1 - 0.021 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 AAG04075.1 - 0.035 14.1 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 AAG04075.1 - 0.04 14.4 0.0 0.079 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 AAG04075.1 - 0.044 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_21 PF13304.6 AAG04075.1 - 0.05 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 AAG04075.1 - 0.083 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DEAD PF00270.29 AAG04075.1 - 0.12 12.1 0.1 0.65 9.7 0.0 2.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase cobW PF02492.19 AAG04075.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 AAG04075.1 - 0.23 10.7 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSF PF00482.23 AAG04076.1 - 3.3e-60 201.5 15.7 1.5e-31 108.9 2.3 2.5 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F Prok-E2_C PF14459.6 AAG04076.1 - 0.0056 16.8 0.4 0.98 9.6 0.0 2.7 2 1 1 3 3 3 2 Prokaryotic E2 family C DUF2062 PF09835.9 AAG04076.1 - 0.0095 15.8 0.6 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF1056 PF06341.11 AAG04076.1 - 0.067 13.5 0.5 0.067 13.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) PBP_like_2 PF12849.7 AAG04077.1 - 4e-30 105.5 10.3 6e-30 104.9 10.3 1.1 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AAG04077.1 - 0.0011 18.1 0.0 0.0026 16.9 0.0 1.7 1 1 0 1 1 1 1 PBP superfamily domain PBP_like_2 PF12849.7 AAG04078.1 - 9e-23 81.3 0.9 1.4e-22 80.8 0.9 1.1 1 0 0 1 1 1 1 PBP superfamily domain DUF3739 PF12545.8 AAG04079.1 - 6.1e-39 132.9 3.7 6.1e-39 132.9 3.7 7.5 9 0 0 9 9 9 1 Filamentous haemagglutinin family outer membrane protein Haemagg_act PF05860.13 AAG04079.1 - 6.4e-24 84.2 2.4 6.4e-24 84.2 2.4 2.5 2 0 0 2 2 2 1 haemagglutination activity domain DUF772 PF05598.11 AAG04080.1 - 3.9e-11 42.8 0.1 6.1e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Transposase domain (DUF772) PhdYeFM_antitox PF02604.19 AAG04080.1 - 0.0034 17.1 0.0 0.0091 15.8 0.0 1.7 2 0 0 2 2 2 1 Antitoxin Phd_YefM, type II toxin-antitoxin system ShlB PF03865.13 AAG04081.1 - 1.3e-21 77.4 7.0 2e-21 76.7 7.0 1.4 1 1 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AAG04081.1 - 2.4e-18 65.8 0.5 6.3e-18 64.4 0.3 1.9 2 0 0 2 2 2 1 POTRA domain, ShlB-type POTRA PF07244.15 AAG04081.1 - 0.00018 22.0 0.1 0.52 10.9 0.1 2.6 2 0 0 2 2 2 2 Surface antigen variable number repeat Bac_surface_Ag PF01103.23 AAG04081.1 - 0.00042 19.9 2.8 0.0024 17.4 2.8 2.5 1 1 0 1 1 1 1 Surface antigen MotA_ExbB PF01618.16 AAG04082.1 - 9.7e-28 96.5 1.3 2.1e-27 95.3 1.3 1.6 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF2341 PF10102.9 AAG04082.1 - 1.3e-22 80.1 0.0 2.5e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2341) Laminin_G_3 PF13385.6 AAG04082.1 - 4.3e-15 56.2 0.0 1e-13 51.7 0.0 2.5 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1080 PF06439.11 AAG04082.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.24 AAG04082.1 - 0.023 15.3 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain ExbD PF02472.16 AAG04083.1 - 1e-28 100.1 0.7 1.2e-28 99.9 0.7 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_2 PF13103.6 AAG04084.1 - 2.4e-06 27.7 0.0 2.4e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 TonB C terminal TonB_C PF03544.14 AAG04084.1 - 0.034 14.6 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal Porin_5 PF16930.5 AAG04085.1 - 4.4e-224 744.9 0.1 5e-224 744.7 0.1 1.0 1 0 0 1 1 1 1 Putative porin OMP_b-brl PF13505.6 AAG04085.1 - 0.00075 19.7 13.3 0.016 15.3 1.4 3.7 2 2 1 3 3 3 2 Outer membrane protein beta-barrel domain DUF2680 PF10925.8 AAG04085.1 - 0.074 13.1 0.5 0.16 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) JIP_LZII PF16471.5 AAG04086.1 - 0.002 18.2 1.1 0.002 18.2 1.1 2.1 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 AAG04086.1 - 0.054 12.8 17.5 0.068 12.5 17.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SKA2 PF16740.5 AAG04086.1 - 0.094 12.5 15.7 0.039 13.7 4.8 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Occludin_ELL PF07303.13 AAG04086.1 - 0.14 12.8 13.0 0.041 14.6 2.6 2.8 1 1 1 2 2 2 0 Occludin homology domain GramPos_pilinD1 PF16555.5 AAG04086.1 - 0.29 11.3 5.7 0.62 10.2 5.7 1.7 1 1 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain MbeB_N PF04837.12 AAG04086.1 - 0.32 11.3 6.6 4.5 7.7 2.3 3.1 2 1 0 2 2 2 0 MbeB-like, N-term conserved region DUF948 PF06103.11 AAG04086.1 - 0.46 10.8 6.5 2.7 8.3 2.7 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3138 PF11336.8 AAG04086.1 - 0.46 9.0 12.0 0.53 8.8 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SHE3 PF17078.5 AAG04086.1 - 0.49 10.1 11.5 1.3 8.7 11.7 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 AAG04086.1 - 0.7 7.7 9.4 0.8 7.5 9.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 AAG04086.1 - 0.76 10.3 27.9 1.2 9.7 14.9 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 AAG04086.1 - 0.84 9.4 28.4 1.3 8.7 28.4 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family E2F_CC-MB PF16421.5 AAG04086.1 - 1 9.8 10.4 2 8.8 0.1 3.1 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain FUSC PF04632.12 AAG04086.1 - 1.2 7.6 17.2 1.5 7.2 17.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlaC_arch PF05377.11 AAG04086.1 - 1.4 9.3 3.5 13 6.2 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 AAG04086.1 - 1.9 8.7 18.1 42 4.4 17.9 2.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HAUS-augmin3 PF14932.6 AAG04086.1 - 2.6 7.6 26.2 5.6 6.5 7.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 AAG04086.1 - 2.6 8.7 22.8 1.7 9.3 5.4 3.4 1 1 2 3 3 3 0 SlyX Seryl_tRNA_N PF02403.22 AAG04086.1 - 4.2 7.6 18.0 0.29 11.4 9.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 AAG04086.1 - 5 7.3 19.7 0.77 9.9 12.0 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase IFT20 PF14931.6 AAG04086.1 - 6.2 7.0 18.1 0.79 9.9 9.1 2.6 1 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 YabA PF06156.13 AAG04086.1 - 7.1 7.3 11.7 26 5.5 8.0 2.9 1 1 1 2 2 2 0 Initiation control protein YabA TolA_bind_tri PF16331.5 AAG04086.1 - 7.2 6.8 24.7 0.18 11.9 6.7 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation Spc7 PF08317.11 AAG04086.1 - 7.8 5.3 21.8 46 2.8 21.4 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-Q PF13094.6 AAG04086.1 - 9.7 6.4 23.8 3.5 7.8 17.6 2.2 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit YbjN PF10722.9 AAG04087.1 - 4.4e-17 62.3 0.0 5.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator Rotamase_2 PF13145.6 AAG04088.1 - 4.6e-22 79.1 0.3 4.6e-22 79.1 0.3 2.4 2 1 0 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAG04088.1 - 4.3e-19 69.3 0.2 1.8e-18 67.2 0.0 2.1 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AAG04088.1 - 1.9e-15 57.4 0.0 4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Nitr_red_assoc PF09655.10 AAG04088.1 - 0.035 14.7 0.9 0.084 13.5 0.9 1.6 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) LPAM_2 PF13627.6 AAG04088.1 - 0.055 13.3 1.6 0.13 12.1 1.6 1.7 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Arm-DNA-bind_3 PF13356.6 AAG04088.1 - 0.075 13.4 0.7 0.28 11.6 0.7 2.1 1 0 0 1 1 1 0 Arm DNA-binding domain DUF3558 PF12079.8 AAG04088.1 - 0.11 12.5 0.9 0.18 11.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) DinB_2 PF12867.7 AAG04088.1 - 2.1 8.9 11.3 24 5.5 2.6 3.4 2 1 1 3 3 3 0 DinB superfamily DUF4054 PF13262.6 AAG04089.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) HTH_1 PF00126.27 AAG04090.1 - 5.2e-10 39.1 0.2 1.6e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAG04090.1 - 2.2e-07 30.5 7.8 6e-07 29.0 7.8 1.9 1 1 0 1 1 1 1 LysR substrate binding domain FA_hydroxylase PF04116.13 AAG04091.1 - 2e-21 76.7 6.5 3.8e-21 75.8 6.5 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Sugar_tr PF00083.24 AAG04092.1 - 5.7e-28 98.0 16.7 2e-19 69.8 4.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAG04092.1 - 3.2e-23 82.2 73.4 2.5e-19 69.4 44.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.21 AAG04093.1 - 9.5e-89 298.4 0.0 1.5e-88 297.8 0.0 1.3 1 1 0 1 1 1 1 Amidase 2_5_RNA_ligase2 PF13563.6 AAG04093.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Glycos_transf_2 PF00535.26 AAG04094.1 - 4.2e-34 117.8 0.0 7.4e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAG04094.1 - 1.8e-21 77.1 0.0 2.7e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAG04094.1 - 2e-11 43.9 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAG04094.1 - 1.6e-08 34.9 0.2 6.2e-08 33.1 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAG04094.1 - 0.0019 18.1 0.1 0.0043 17.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAG04094.1 - 0.0045 16.5 0.0 0.0078 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Hexapep PF00132.24 AAG04095.1 - 1e-08 34.6 5.0 2.7e-07 30.0 0.2 3.2 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAG04095.1 - 0.032 14.0 0.7 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase EAL PF00563.20 AAG04096.1 - 2.8e-11 43.4 0.3 3.4e-11 43.1 0.3 1.1 1 0 0 1 1 1 1 EAL domain DUF533 PF04391.12 AAG04096.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) LysR_substrate PF03466.20 AAG04097.1 - 1.1e-41 142.5 5.9 1.1e-41 142.5 5.9 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04097.1 - 3.8e-15 55.6 0.2 7.8e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG04097.1 - 0.022 14.5 0.1 0.058 13.2 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain ABM PF03992.16 AAG04098.1 - 4.3e-16 58.8 0.0 4.9e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Glyoxalase PF00903.25 AAG04099.1 - 3.7e-19 69.2 0.1 4.4e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG04099.1 - 3e-11 43.6 0.1 1.1e-10 41.7 0.1 1.7 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG04099.1 - 5.6e-09 36.7 0.3 7e-09 36.4 0.3 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AAG04099.1 - 0.00035 20.7 0.1 0.0052 16.9 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Acetyltransf_9 PF13527.7 AAG04100.1 - 1.4e-10 41.4 0.0 2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG04100.1 - 1.6e-09 38.0 0.0 2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG04100.1 - 2.2e-08 34.4 0.0 3.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG04100.1 - 0.00013 21.8 0.0 0.0013 18.7 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG04100.1 - 0.072 13.1 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein YjhX_toxin PF09857.9 AAG04101.1 - 2.3e-39 133.2 0.0 2.5e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Putative toxin of bacterial toxin-antitoxin pair TrmB PF01978.19 AAG04101.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2845 PF11006.8 AAG04102.1 - 6.2e-17 61.5 0.0 7.2e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2845) zf-FPG_IleRS PF06827.14 AAG04102.1 - 0.11 12.4 0.0 7 6.6 0.0 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS RVT_1 PF00078.27 AAG04104.1 - 1.4e-17 63.9 0.0 2.2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_21 PF13304.6 AAG04105.1 - 2.3e-18 67.1 0.8 7.3e-10 39.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAG04105.1 - 6.1e-15 55.8 0.3 2.3e-06 27.6 0.9 2.1 1 1 1 2 2 2 2 AAA ATPase domain ABC_tran PF00005.27 AAG04105.1 - 3e-08 34.3 0.2 4.1e-07 30.6 0.2 2.2 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 AAG04105.1 - 2.9e-07 30.8 0.0 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AAG04105.1 - 3.2e-07 31.1 0.1 4.6e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAG04105.1 - 7e-07 28.9 0.6 6.7e-05 22.4 0.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 AAG04105.1 - 0.00014 22.2 0.1 0.03 14.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAG04105.1 - 0.00019 21.1 0.1 0.00043 20.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 AAG04105.1 - 0.00038 20.5 0.3 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AAG04105.1 - 0.0014 18.5 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAG04105.1 - 0.0032 17.6 0.1 0.008 16.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 AAG04105.1 - 0.0045 16.9 0.1 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 AAG04105.1 - 0.0068 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 AAG04105.1 - 0.008 16.6 0.0 0.019 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AAG04105.1 - 0.013 15.4 0.1 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Roc PF08477.13 AAG04105.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 AAG04105.1 - 0.018 15.6 0.0 0.057 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAG04105.1 - 0.02 13.6 0.3 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAG04105.1 - 0.042 13.6 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AAG04105.1 - 0.048 13.6 0.4 0.25 11.2 0.2 2.0 2 0 0 2 2 2 0 NTPase MobB PF03205.14 AAG04105.1 - 0.048 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 AAG04105.1 - 0.054 13.0 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 AAG04105.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 AAG04105.1 - 0.12 12.4 0.1 2 8.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 AAG04105.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin TniB PF05621.11 AAG04105.1 - 0.19 11.1 0.1 17 4.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 AAG04105.1 - 0.27 11.0 0.1 0.72 9.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain PknH_C PF14032.6 AAG04106.1 - 0.043 13.7 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 PknH-like extracellular domain MbtH PF03621.13 AAG04106.1 - 0.084 12.3 0.8 0.13 11.7 0.8 1.3 1 0 0 1 1 1 0 MbtH-like protein DUF5447 PF17525.2 AAG04107.1 - 2.5e-48 162.5 8.7 2.8e-48 162.3 8.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5447) LapA_dom PF06305.11 AAG04111.1 - 0.59 10.0 4.2 0.36 10.7 2.1 1.8 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Phage_Coat_B PF05356.11 AAG04112.1 - 1e-52 176.0 3.3 1.1e-52 175.9 3.3 1.0 1 0 0 1 1 1 1 Phage Coat protein B CoatB PF10389.9 AAG04112.1 - 0.0032 17.3 2.4 0.0032 17.3 2.4 1.6 2 0 0 2 2 2 1 Bacteriophage coat protein B FeoB_associated PF12669.7 AAG04112.1 - 0.021 15.2 1.1 0.035 14.5 1.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2975 PF11188.8 AAG04112.1 - 0.057 13.3 0.8 0.064 13.1 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) TM_helix PF05552.12 AAG04112.1 - 0.072 13.1 0.7 0.12 12.4 0.7 1.4 1 0 0 1 1 1 0 Conserved TM helix Insulin_TMD PF17870.1 AAG04112.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PTP_tm PF18861.1 AAG04112.1 - 0.59 10.1 2.6 2.1 8.3 2.6 1.8 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J CBM_14 PF01607.24 AAG04113.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.9 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain DUF2523 PF10734.9 AAG04114.1 - 2.6e-09 37.5 2.2 4.2e-09 36.8 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2523) Zot PF05707.12 AAG04115.1 - 8.1e-68 227.9 0.0 1e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Dynein_heavy PF03028.15 AAG04116.1 - 0.0035 17.4 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Phage_integrase PF00589.22 AAG04117.1 - 2.7e-21 76.1 4.5 8.9e-11 41.9 2.7 2.7 2 1 1 3 3 3 2 Phage integrase family Arm-DNA-bind_4 PF14657.6 AAG04117.1 - 0.018 14.8 0.7 0.03 14.1 0.7 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain ParE_toxin PF05016.15 AAG04118.1 - 2.2e-11 44.2 0.0 2.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Abhydrolase_1 PF00561.20 AAG04119.1 - 1.1e-10 41.6 0.0 2.7e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG04119.1 - 1.8e-08 35.3 0.1 2.4e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG04119.1 - 5.1e-08 32.5 0.0 1.6e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 RFX_DNA_binding PF02257.15 AAG04119.1 - 0.027 15.1 0.1 0.37 11.4 0.1 2.5 3 0 0 3 3 3 0 RFX DNA-binding domain Abhydrolase_4 PF08386.10 AAG04119.1 - 0.037 14.2 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein CBM_35 PF16990.5 AAG04119.1 - 0.083 13.1 0.1 0.22 11.8 0.1 1.6 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) Esterase PF00756.20 AAG04119.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase YkuD_2 PF13645.6 AAG04120.1 - 9.4e-64 213.9 0.0 1.2e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain YkuD PF03734.14 AAG04120.1 - 0.0017 18.8 0.0 0.0025 18.3 0.0 1.2 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain YkuD PF03734.14 AAG04121.1 - 8.7e-21 74.9 0.0 2.2e-18 67.0 0.0 2.4 2 0 0 2 2 2 2 L,D-transpeptidase catalytic domain PseudoU_synth_2 PF00849.22 AAG04122.1 - 3.4e-13 50.0 0.0 1.2e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAG04122.1 - 6e-09 35.5 0.1 9.8e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 S4 domain Cys_rich_CWC PF14375.6 AAG04123.1 - 7.9e-14 51.8 12.5 1e-13 51.5 12.5 1.1 1 0 0 1 1 1 1 Cysteine-rich CWC DUF4824 PF16106.5 AAG04124.1 - 4.3e-91 304.7 2.7 4.9e-91 304.5 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4824) DUF2157 PF09925.9 AAG04125.1 - 1.7e-15 57.1 14.7 1.7e-15 57.1 14.7 3.7 1 1 2 3 3 3 1 Predicted membrane protein (DUF2157) DUF1145 PF06611.12 AAG04127.1 - 8.2e-14 51.3 5.1 8.2e-14 51.3 5.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1145) LysR_substrate PF03466.20 AAG04128.1 - 6.6e-32 110.6 10.1 6.6e-32 110.6 10.1 1.7 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04128.1 - 4.6e-22 77.7 1.5 1.3e-21 76.3 1.5 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AAG04128.1 - 0.06 13.5 0.1 0.2 11.8 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Alkyl_sulf_dimr PF14863.6 AAG04129.1 - 4.5e-56 189.1 0.5 7.9e-56 188.4 0.5 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 AAG04129.1 - 3.5e-48 164.2 0.0 5.8e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 AAG04129.1 - 7.9e-33 113.4 0.0 1.5e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 AAG04129.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SCP2 PF02036.17 AAG04129.1 - 0.0008 19.9 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family NAD_binding_10 PF13460.6 AAG04130.1 - 5.3e-35 121.0 0.0 6e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAG04130.1 - 6.8e-13 48.7 0.5 9.4e-13 48.3 0.5 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 AAG04130.1 - 2.9e-08 33.5 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG04130.1 - 0.00086 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAG04130.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.16 AAG04130.1 - 0.023 14.3 0.2 0.27 10.9 0.1 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.12 AAG04130.1 - 0.088 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein GDP_Man_Dehyd PF16363.5 AAG04130.1 - 0.096 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 AAG04130.1 - 0.16 12.2 0.1 0.24 11.7 0.1 1.2 1 0 0 1 1 1 0 TrkA-N domain Ion_trans_2 PF07885.16 AAG04131.1 - 2.6e-13 49.7 3.4 5e-13 48.8 3.4 1.5 1 1 0 1 1 1 1 Ion channel BofA PF07441.11 AAG04131.1 - 0.035 14.3 1.1 0.053 13.7 0.7 1.6 1 1 0 1 1 1 0 SigmaK-factor processing regulatory protein BofA Cytochrom_B561 PF03188.16 AAG04131.1 - 0.17 12.0 2.5 0.22 11.7 2.5 1.3 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 Peptidase_A24 PF01478.18 AAG04131.1 - 0.28 11.6 4.0 0.35 11.3 4.0 1.2 1 0 0 1 1 1 0 Type IV leader peptidase family NAD_binding_2 PF03446.15 AAG04132.1 - 1.8e-53 180.9 1.0 2.7e-53 180.3 1.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAG04132.1 - 3.3e-33 114.5 0.7 6.1e-33 113.7 0.7 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AAG04132.1 - 9.8e-06 26.1 0.6 0.00018 22.0 0.4 3.0 3 2 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AAG04132.1 - 0.0044 16.4 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AAG04132.1 - 0.0068 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 AAG04132.1 - 0.02 14.8 0.3 0.02 14.8 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAG04132.1 - 0.035 13.7 0.0 0.27 10.8 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ECH_2 PF16113.5 AAG04133.1 - 3.4e-111 371.9 0.0 3.9e-111 371.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AAG04133.1 - 2.8e-21 76.0 0.0 5.9e-21 74.9 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AAG04134.1 - 6.8e-53 179.6 0.0 8.4e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG04134.1 - 9.6e-28 97.6 0.1 4.4e-23 82.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Acyl-CoA_dh_1 PF00441.24 AAG04135.1 - 9.1e-49 165.5 1.5 1.5e-48 164.8 1.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG04135.1 - 2.5e-30 105.4 0.3 5.5e-30 104.3 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG04135.1 - 9.7e-28 96.2 0.0 2.1e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG04135.1 - 2.6e-22 79.5 0.3 5.7e-22 78.4 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG04135.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Aldedh PF00171.22 AAG04136.1 - 1.3e-137 459.2 0.0 1.4e-137 459.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAG04136.1 - 0.099 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) VanW PF04294.13 AAG04138.1 - 1.5e-33 115.2 0.0 2e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 VanW like protein UDG PF03167.19 AAG04139.1 - 5.1e-25 88.3 0.1 6.6e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily AbrB PF05145.12 AAG04140.1 - 5.9e-84 281.7 31.1 5.9e-84 281.7 31.1 1.3 2 0 0 2 2 2 1 Transition state regulatory protein AbrB SLATT_fungal PF18142.1 AAG04140.1 - 0.05 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain TctA PF01970.16 AAG04141.1 - 4.5e-138 460.4 44.8 4.5e-138 460.4 44.8 1.9 2 0 0 2 2 2 2 Tripartite tricarboxylate transporter TctA family TctB PF07331.11 AAG04142.1 - 1.6e-17 64.0 13.3 1.9e-17 63.8 13.3 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family CrgA PF06781.12 AAG04142.1 - 0.28 11.3 2.7 1.2 9.2 0.1 2.8 2 1 1 3 3 3 0 Cell division protein CrgA TctC PF03401.14 AAG04143.1 - 1.9e-24 86.2 0.0 2.3e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor Phosphonate-bd PF12974.7 AAG04143.1 - 0.0014 18.2 0.1 0.0021 17.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein OprD PF03573.13 AAG04144.1 - 1.6e-168 560.8 1.5 1.8e-168 560.7 1.5 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Porin_4 PF13609.6 AAG04144.1 - 0.00062 19.6 3.7 0.0013 18.5 3.7 1.6 1 1 0 1 1 1 1 Gram-negative porin Response_reg PF00072.24 AAG04145.1 - 4.1e-26 91.4 0.0 6.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG04145.1 - 1.1e-18 67.0 0.0 2.3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal 2CSK_N PF08521.10 AAG04146.1 - 4.1e-41 140.3 1.0 4.1e-41 140.3 1.0 2.5 3 0 0 3 3 3 1 Two-component sensor kinase N-terminal HATPase_c PF02518.26 AAG04146.1 - 1.5e-17 64.1 0.0 2.4e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG04146.1 - 1.8e-13 50.3 3.7 2.5e-13 49.8 1.5 2.5 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAG04146.1 - 1e-05 25.8 8.6 0.0001 22.6 1.2 3.4 3 0 0 3 3 3 2 HAMP domain CopD PF05425.13 AAG04146.1 - 0.8 10.1 8.1 4.1 7.8 1.4 3.3 2 1 1 3 3 3 0 Copper resistance protein D HDOD PF08668.12 AAG04147.1 - 2.3e-47 161.0 0.1 3.1e-47 160.6 0.1 1.2 1 0 0 1 1 1 1 HDOD domain GCV_T PF01571.21 AAG04148.1 - 6e-05 22.5 0.0 0.0007 19.0 0.0 2.1 1 1 1 2 2 2 2 Aminomethyltransferase folate-binding domain Sdh5 PF03937.16 AAG04149.1 - 7.7e-25 86.7 0.7 8.8e-25 86.5 0.7 1.0 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase FAD_binding_2 PF00890.24 AAG04150.1 - 2.8e-107 359.4 0.3 4.1e-107 358.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAG04150.1 - 1.7e-13 50.7 0.0 4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AAG04150.1 - 7.6e-07 28.6 0.2 0.0077 15.5 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAG04150.1 - 9.2e-07 28.7 3.5 1.8e-06 27.8 3.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG04150.1 - 4.6e-05 22.8 0.2 0.0017 17.7 0.1 2.7 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 AAG04150.1 - 0.0013 18.0 0.7 0.053 12.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AAG04150.1 - 0.019 14.0 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 AAG04150.1 - 0.086 11.5 0.1 0.71 8.5 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.6 AAG04150.1 - 0.13 12.5 0.2 0.44 10.8 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sigma70_r4_2 PF08281.12 AAG04151.1 - 1.2e-18 66.5 0.1 3.1e-18 65.2 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG04151.1 - 6.4e-18 64.3 0.9 1.2e-17 63.4 0.9 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG04151.1 - 1.8e-10 40.1 0.1 3.7e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG04151.1 - 1.6e-08 34.7 0.6 2.2e-08 34.2 0.6 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AAG04151.1 - 0.0046 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_16 PF12645.7 AAG04151.1 - 0.014 15.4 0.1 0.035 14.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 AAG04151.1 - 0.02 14.8 0.1 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q Acetyltransf_14 PF03421.16 AAG04151.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase POTRA_TamA_1 PF17243.2 AAG04151.1 - 3.4 7.8 5.6 10 6.3 0.1 3.2 3 1 1 4 4 4 0 POTRA domain TamA domain 1 RseA_N PF03872.13 AAG04152.1 - 1.6e-16 60.6 0.1 3.1e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Anti sigma-E protein RseA, N-terminal domain RseA_C PF03873.13 AAG04152.1 - 1.2e-11 44.6 1.4 1.2e-11 44.6 1.4 1.8 2 0 0 2 2 2 1 Anti sigma-E protein RseA, C-terminal domain gp37_C PF12604.8 AAG04152.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Tail fibre protein gp37 C terminal RskA PF10099.9 AAG04152.1 - 0.39 11.0 11.7 0.6 10.4 11.0 1.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA MucB_RseB PF03888.14 AAG04153.1 - 6.4e-56 188.7 0.0 8.4e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 MucB/RseB N-terminal domain MucB_RseB_C PF17188.4 AAG04153.1 - 7.1e-24 83.9 0.0 1.3e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 MucB/RseB C-terminal domain LolA_like PF17131.4 AAG04153.1 - 0.00019 21.2 0.0 0.00098 18.9 0.0 1.8 2 0 0 2 2 2 1 Outer membrane lipoprotein-sorting protein RseC_MucC PF04246.12 AAG04154.1 - 3.6e-32 111.0 0.0 4.1e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC DUF485 PF04341.12 AAG04154.1 - 0.0079 16.1 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF485 SLATT_1 PF18181.1 AAG04154.1 - 0.011 15.6 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 PGF-CTERM PF18204.1 AAG04154.1 - 0.073 13.1 1.0 0.073 13.1 1.0 2.5 2 0 0 2 2 2 0 PGF-CTERM motif Trypsin_2 PF13365.6 AAG04155.1 - 3.5e-35 122.1 0.1 7.1e-35 121.1 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAG04155.1 - 3.1e-31 107.5 1.9 2.2e-18 66.3 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 AAG04155.1 - 1.3e-19 69.7 3.3 1.1e-09 38.0 0.3 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AAG04155.1 - 1.4e-19 70.2 4.4 2.6e-10 40.5 0.5 2.6 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 AAG04155.1 - 1.7e-14 54.2 0.0 2.8e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 AAG04155.1 - 7.8e-06 25.8 0.6 0.0077 16.2 0.1 2.6 2 0 0 2 2 2 2 Tricorn protease PDZ domain PDZ_1 PF12812.7 AAG04155.1 - 4.1e-05 23.5 0.1 0.00041 20.3 0.0 2.5 2 1 1 3 3 3 1 PDZ-like domain Peptidase_S46 PF10459.9 AAG04155.1 - 5.4e-05 22.1 0.1 0.044 12.4 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S29 PF02907.15 AAG04155.1 - 0.096 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease GTP_EFTU PF00009.27 AAG04156.1 - 1.2e-51 175.1 0.1 1.7e-51 174.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 AAG04156.1 - 3.7e-51 171.8 2.3 6.8e-51 170.9 2.3 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AAG04156.1 - 4.9e-20 71.3 0.0 7.9e-19 67.5 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAG04156.1 - 6.1e-11 42.5 3.6 2.1e-10 40.8 3.6 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 AAG04156.1 - 7.6e-06 25.9 0.0 2.2e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 AAG04156.1 - 2.3e-05 24.0 0.0 5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 AAG04156.1 - 0.00022 21.3 0.1 0.0008 19.5 0.0 2.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase RF3_C PF16658.5 AAG04156.1 - 0.023 14.5 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 AAG04156.1 - 0.038 13.4 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 AAG04156.1 - 0.13 12.1 0.2 0.71 9.8 0.0 2.2 2 1 1 3 3 3 0 RsgA GTPase Peptidase_S24 PF00717.23 AAG04157.1 - 6.2e-22 77.3 0.3 1.1e-21 76.6 0.3 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 AAG04157.1 - 3.1e-07 30.2 0.0 0.0058 16.4 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF4845 PF16137.5 AAG04158.1 - 9e-24 84.2 0.3 1.1e-23 83.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4845) N_methyl PF07963.12 AAG04158.1 - 0.0037 16.8 0.2 0.0051 16.3 0.2 1.2 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Ribonucleas_3_3 PF14622.6 AAG04159.1 - 2.3e-35 121.5 0.0 3e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 AAG04159.1 - 8.5e-22 77.8 0.0 1.6e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 AAG04159.1 - 4.6e-08 33.6 0.0 6.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif MMR_HSR1 PF01926.23 AAG04160.1 - 1.1e-23 83.5 0.1 1.9e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 AAG04160.1 - 5.1e-21 74.3 2.6 1e-20 73.3 2.6 1.6 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 AAG04160.1 - 3e-15 56.1 0.1 4.3e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 AAG04160.1 - 4.3e-11 42.6 0.2 1.1e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 AAG04160.1 - 1.6e-09 38.1 0.2 2.1e-05 24.6 0.1 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 AAG04160.1 - 2.1e-09 37.2 0.5 1.8e-05 24.4 0.2 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AAG04160.1 - 5e-08 33.0 0.9 0.0005 20.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 AAG04160.1 - 6.9e-07 29.0 0.8 0.00016 21.3 0.1 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 AAG04160.1 - 9.6e-05 22.2 0.0 0.0012 18.7 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 AAG04160.1 - 0.00015 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 AAG04160.1 - 0.00021 20.8 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 AAG04160.1 - 0.0007 19.1 0.1 0.0018 17.7 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 AAG04160.1 - 0.0039 17.4 0.1 0.013 15.7 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 AAG04160.1 - 0.0071 16.7 0.4 0.23 11.8 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain Ploopntkinase3 PF18751.1 AAG04160.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 AAG04160.1 - 0.012 16.1 0.2 0.037 14.6 0.1 1.8 1 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 AAG04160.1 - 0.028 14.7 0.4 0.14 12.4 0.4 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAG04160.1 - 0.11 11.9 0.2 1.4 8.2 0.0 2.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 AAG04160.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAG04160.1 - 0.28 11.1 1.7 2.8 7.8 0.0 2.3 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea RecO_C PF02565.15 AAG04161.1 - 6e-23 81.4 2.4 7.6e-23 81.0 2.4 1.1 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 AAG04161.1 - 1.4e-15 57.0 0.0 2.7e-15 56.1 0.0 1.5 2 0 0 2 2 2 1 Recombination protein O N terminal PdxJ PF03740.13 AAG04162.1 - 1.3e-102 341.9 1.5 1.5e-102 341.7 1.5 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ AP_endonuc_2 PF01261.24 AAG04162.1 - 0.013 14.9 2.1 0.38 10.2 2.1 2.9 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_trans_4_4 PF13579.6 AAG04162.1 - 0.033 14.6 1.8 0.033 14.6 1.8 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain TOH_N PF12549.8 AAG04162.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Methyltransf_9 PF08003.11 AAG04163.1 - 7.8e-138 458.7 0.0 8.9e-138 458.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 AAG04163.1 - 6.4e-12 45.6 0.0 1.5e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG04163.1 - 1.1e-08 35.6 0.0 5.4e-08 33.4 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG04163.1 - 1.5e-08 34.6 0.0 4.3e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG04163.1 - 3.3e-08 34.1 0.0 1.1e-07 32.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG04163.1 - 1.2e-05 25.9 0.0 2.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAG04163.1 - 0.063 12.6 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 AAG04163.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 AAG04164.1 - 8.3e-12 45.7 0.0 1.7e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG04164.1 - 1.5e-10 41.6 0.0 3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG04164.1 - 1.1e-08 35.0 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG04164.1 - 1.7e-08 35.1 0.0 3.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG04164.1 - 5.5e-08 32.8 0.0 1.4e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAG04164.1 - 0.0006 19.2 0.0 0.00089 18.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 AAG04164.1 - 0.015 15.4 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase CheR PF01739.18 AAG04164.1 - 0.023 14.2 0.0 3.2 7.2 0.0 2.3 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Rsm22 PF09243.10 AAG04164.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 SBP_bac_3 PF00497.20 AAG04166.1 - 2.8e-05 23.7 0.0 4.7e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 MLD PF11647.8 AAG04166.1 - 0.2 11.9 0.2 0.59 10.4 0.1 1.7 2 0 0 2 2 2 0 Membrane Localization Domain Inhibitor_I42 PF09394.10 AAG04167.1 - 5.7e-22 77.9 0.0 7.2e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Lon_C PF05362.13 AAG04168.1 - 2.3e-79 265.7 0.0 4e-79 264.9 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 AAG04168.1 - 2.1e-25 89.8 0.0 3.9e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 AAG04168.1 - 9.9e-23 81.0 0.0 1.7e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 AAG04168.1 - 8.3e-08 32.1 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 AAG04168.1 - 1.9e-07 31.1 0.0 3.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAG04168.1 - 2e-05 25.1 0.2 0.00023 21.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 AAG04168.1 - 0.00019 20.5 0.0 0.0004 19.4 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 AAG04168.1 - 0.00027 20.7 0.0 0.0016 18.2 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAG04168.1 - 0.0014 18.9 0.1 0.059 13.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AAG04168.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AAG04168.1 - 0.0018 18.8 0.1 0.0077 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 AAG04168.1 - 0.0054 16.0 0.1 0.0099 15.1 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 AAG04168.1 - 0.0082 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) SKI PF01202.22 AAG04168.1 - 0.0093 16.1 0.4 0.047 13.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase IstB_IS21 PF01695.17 AAG04168.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 AAG04168.1 - 0.091 13.2 1.5 0.26 11.7 0.1 2.5 3 1 1 4 4 3 0 AAA domain AAA_14 PF13173.6 AAG04168.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAG04168.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAG04168.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 AAG04168.1 - 0.17 12.4 0.8 0.75 10.3 0.1 2.1 2 0 0 2 2 2 0 ABC transporter HTH_18 PF12833.7 AAG04169.1 - 4.6e-22 78.1 0.1 7.6e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04169.1 - 5.3e-20 71.0 0.0 1.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG04169.1 - 0.01 15.6 0.2 0.022 14.4 0.2 1.6 1 0 0 1 1 1 1 Cupin domain HTH_23 PF13384.6 AAG04169.1 - 0.012 15.4 0.4 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 AAG04169.1 - 0.013 15.3 1.2 4.1 7.3 0.2 2.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TonB_dep_Rec PF00593.24 AAG04170.1 - 4.5e-43 148.8 11.8 6e-43 148.4 11.8 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG04170.1 - 1.2e-20 74.0 0.8 4.7e-20 72.2 0.3 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG04170.1 - 0.18 10.7 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family OMP_b-brl PF13505.6 AAG04170.1 - 0.21 11.7 10.7 13 5.8 3.7 3.9 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain Aldedh PF00171.22 AAG04171.1 - 2.1e-115 385.9 0.3 2.9e-115 385.4 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 AAG04171.1 - 7e-96 321.2 0.0 2.6e-95 319.4 0.0 1.9 2 0 0 2 2 2 1 Proline dehydrogenase Pro_dh-DNA_bdg PF14850.6 AAG04171.1 - 9e-46 155.0 0.6 2.2e-45 153.8 0.2 2.0 2 0 0 2 2 2 1 DNA-binding domain of Proline dehydrogenase PRODH PF18327.1 AAG04171.1 - 0.00085 19.5 0.1 0.00085 19.5 0.1 3.0 3 0 0 3 3 3 1 Proline utilization A proline dehydrogenase N-terminal domain SSF PF00474.17 AAG04172.1 - 6.8e-139 463.2 27.7 1e-138 462.6 27.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family LysR_substrate PF03466.20 AAG04173.1 - 6.2e-27 94.3 1.8 9.7e-27 93.7 1.8 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04173.1 - 2e-19 69.3 0.7 3.7e-19 68.4 0.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Flavodoxin_2 PF02525.17 AAG04174.1 - 6.8e-44 149.9 0.0 7.8e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAG04174.1 - 4.2e-15 55.8 0.0 5.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Multi_Drug_Res PF00893.19 AAG04175.1 - 9.6e-24 83.9 8.4 1.1e-23 83.7 8.4 1.0 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAG04175.1 - 4e-06 27.0 14.0 5.7e-06 26.5 14.0 1.2 1 0 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 AAG04175.1 - 0.00077 19.5 1.0 0.00085 19.3 1.0 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 Sugar_transport PF06800.12 AAG04175.1 - 0.091 12.1 6.8 0.13 11.6 1.7 2.0 1 1 1 2 2 2 0 Sugar transport protein SLATT_6 PF18169.1 AAG04175.1 - 6.6 6.3 5.0 3.4 7.2 2.1 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 AAA_21 PF13304.6 AAG04176.1 - 1.8e-26 93.7 0.1 1.7e-17 64.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAG04176.1 - 7.9e-13 48.9 0.0 2.4e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AAG04176.1 - 2.2e-09 37.1 0.0 6.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG04176.1 - 0.0002 21.9 0.0 0.00029 21.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG04176.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAG04176.1 - 0.0078 16.7 0.0 0.049 14.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 AAG04176.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 AAG04176.1 - 0.023 13.4 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAG04176.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 AAG04176.1 - 0.045 13.0 0.3 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_18 PF13238.6 AAG04176.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Transgly PF00912.22 AAG04177.1 - 4.7e-26 91.3 0.0 9.4e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AAG04177.1 - 2.3e-06 27.0 0.0 0.00019 20.8 0.0 2.5 2 0 0 2 2 2 2 Penicillin binding protein transpeptidase domain AA_permease PF00324.21 AAG04178.1 - 1.8e-117 392.9 49.0 2.2e-117 392.6 49.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG04178.1 - 2.8e-48 164.8 49.6 3.2e-48 164.6 49.6 1.1 1 0 0 1 1 1 1 Amino acid permease TauE PF01925.19 AAG04179.1 - 1.6e-37 129.4 34.5 2.1e-37 129.1 34.5 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE CoA_binding_3 PF13727.6 AAG04179.1 - 0.035 14.1 0.9 0.057 13.4 0.9 1.4 1 0 0 1 1 1 0 CoA-binding domain Peptidase_M48 PF01435.18 AAG04179.1 - 0.058 13.2 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 DUF4516 PF14990.6 AAG04179.1 - 0.91 9.3 3.0 0.97 9.2 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) HTH_18 PF12833.7 AAG04180.1 - 1.7e-19 69.9 1.1 3.7e-19 68.8 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04180.1 - 2.3e-11 43.5 0.1 4.6e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG04180.1 - 1.9e-08 34.3 0.0 3.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG04180.1 - 9.4e-06 25.3 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_23 PF13384.6 AAG04180.1 - 0.0018 18.0 1.4 1.8 8.4 0.0 3.2 3 0 0 3 3 3 2 Homeodomain-like domain DMSP_lyase PF16867.5 AAG04180.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase MmgE_PrpD PF03972.14 AAG04181.1 - 2.5e-151 504.2 0.0 2.8e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PrpF PF04303.13 AAG04182.1 - 2.5e-185 615.7 0.0 2.9e-185 615.6 0.0 1.0 1 0 0 1 1 1 1 PrpF protein Aconitase PF00330.20 AAG04183.1 - 1.5e-149 498.9 0.0 2e-149 498.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AAG04183.1 - 8.4e-30 103.8 0.0 1.4e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Citrate_synt PF00285.21 AAG04184.1 - 6e-120 400.6 0.0 7e-120 400.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PEP_mutase PF13714.6 AAG04185.1 - 9.5e-50 169.3 5.3 1.1e-49 169.1 5.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AAG04185.1 - 8.9e-13 47.6 1.7 1.7e-12 46.6 1.7 1.5 1 1 1 2 2 2 2 Isocitrate lyase family DUF4936 PF16290.5 AAG04185.1 - 0.028 15.1 0.6 0.078 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) MraZ PF02381.18 AAG04185.1 - 0.084 12.9 0.0 0.25 11.4 0.0 1.8 1 1 1 2 2 2 0 MraZ protein, putative antitoxin-like FCD PF07729.12 AAG04186.1 - 4.6e-30 104.6 5.6 7.5e-30 103.9 5.6 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAG04186.1 - 4.4e-16 58.3 0.1 9.5e-16 57.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAG04186.1 - 0.026 14.4 1.5 6.5 6.7 0.1 2.6 2 0 0 2 2 2 0 MarR family Methyltransf_23 PF13489.6 AAG04187.1 - 1.7e-20 73.5 0.0 6.3e-20 71.7 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG04187.1 - 5.1e-16 59.1 0.0 8.8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG04187.1 - 1.8e-15 57.4 0.0 1e-14 55.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG04187.1 - 3.7e-12 46.3 0.0 2e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG04187.1 - 1.5e-10 41.7 0.0 3.1e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAG04187.1 - 3.9e-09 36.2 0.0 8.9e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 AAG04187.1 - 0.00015 20.8 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 AAG04187.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Pox_MCEL PF03291.16 AAG04187.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_8 PF05148.15 AAG04187.1 - 0.24 11.2 0.0 0.32 10.8 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase SNF2_N PF00176.23 AAG04188.1 - 4.7e-64 216.3 0.0 1.2e-63 215.0 0.0 1.4 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AAG04188.1 - 3.4e-17 62.8 0.0 5.8e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAG04188.1 - 1.6e-06 28.2 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3649 PF12365.8 AAG04189.1 - 4.7e-07 29.4 18.4 4.7e-07 29.4 18.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3649) DUF3464 PF11947.8 AAG04189.1 - 0.37 10.5 1.5 0.72 9.6 1.4 1.5 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2530 PF10745.9 AAG04189.1 - 3.5 7.9 9.5 0.86 9.9 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Peptidase_U4 PF03419.13 AAG04189.1 - 4.4 6.5 5.2 5.7 6.1 5.2 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA PepSY_TM PF03929.16 AAG04190.1 - 3.5e-59 200.8 12.6 7e-59 199.9 12.6 1.5 1 0 0 1 1 1 1 PepSY-associated TM region DUF3325 PF11804.8 AAG04191.1 - 7.2e-31 106.3 13.6 8.7e-31 106.1 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3325) P5-ATPase PF12409.8 AAG04191.1 - 0.0096 16.0 3.3 0.022 14.9 3.5 1.6 2 0 0 2 2 2 1 P5-type ATPase cation transporter MHYT PF03707.16 AAG04191.1 - 0.16 12.2 4.4 0.41 10.8 1.7 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat TMEM100 PF16311.5 AAG04191.1 - 1.3 8.6 4.4 3.5 7.2 0.1 2.1 1 1 1 2 2 2 0 Transmembrane protein 100 Glyoxalase PF00903.25 AAG04192.1 - 1.2e-06 28.8 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG04192.1 - 1.6e-05 25.6 0.1 2.6e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAG04192.1 - 0.0058 16.9 0.0 0.0072 16.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AAG04192.1 - 0.083 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain SIR2_2 PF13289.6 AAG04192.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain Aldo_ket_red PF00248.21 AAG04193.1 - 2.2e-54 184.7 0.0 1.2e-52 178.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3509 PF12021.8 AAG04194.1 - 0.00056 19.6 0.0 0.00063 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3509) DUF3991 PF13154.6 AAG04194.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) DoxX_2 PF13564.6 AAG04195.1 - 0.00013 22.1 9.6 0.00013 22.1 9.6 1.8 1 1 1 2 2 2 1 DoxX-like family DoxX PF07681.12 AAG04195.1 - 0.00048 20.7 9.0 0.00048 20.7 9.0 1.9 2 0 0 2 2 2 1 DoxX Amidase_2 PF01510.25 AAG04196.1 - 1.1e-24 87.3 0.0 1.5e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 AAG04196.1 - 0.03 14.5 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain AHSA1 PF08327.11 AAG04197.1 - 1.5e-15 57.5 0.0 1.8e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Nramp PF01566.18 AAG04198.1 - 2.7e-127 424.7 20.6 3.3e-127 424.4 20.6 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein HAD_2 PF13419.6 AAG04199.1 - 4.8e-12 46.3 0.0 8.9e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG04199.1 - 1e-07 32.4 0.0 2.3e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG04199.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like MFS_1 PF07690.16 AAG04200.1 - 4.3e-48 164.0 47.1 4.3e-48 164.0 47.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG04200.1 - 0.22 10.3 29.0 0.0093 14.9 4.0 3.3 2 1 1 3 3 3 0 Sugar (and other) transporter BKACE PF05853.12 AAG04201.1 - 1.1e-09 38.0 0.2 2.8e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 beta-keto acid cleavage enzyme Aminotran_5 PF00266.19 AAG04202.1 - 2e-30 106.0 0.0 2.4e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V YjgF_endoribonc PF14588.6 AAG04203.1 - 4.4e-25 88.5 0.7 5.2e-25 88.3 0.7 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 AAG04203.1 - 3e-18 66.0 0.0 4e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP LysR_substrate PF03466.20 AAG04204.1 - 1.6e-34 119.1 6.5 2.5e-34 118.5 6.5 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04204.1 - 9.4e-18 63.9 0.1 2.7e-17 62.4 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG04204.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF1045 PF06299.12 AAG04204.1 - 0.047 13.7 0.7 0.094 12.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) LysR_substrate PF03466.20 AAG04205.1 - 3.9e-40 137.5 9.1 6.9e-40 136.6 9.1 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04205.1 - 1.7e-19 69.5 4.6 3.5e-19 68.5 3.2 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 AAG04205.1 - 0.015 15.1 1.7 0.039 13.8 0.5 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAG04205.1 - 0.065 12.8 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Glyoxalase PF00903.25 AAG04206.1 - 1.9e-08 34.6 0.3 3.4e-08 33.7 0.3 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG04206.1 - 8.2e-06 26.1 0.2 1.1e-05 25.7 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG04206.1 - 0.0032 18.2 0.6 0.0044 17.8 0.6 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain DUF3335 PF11814.8 AAG04206.1 - 0.12 11.9 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family HNH PF01844.23 AAG04209.1 - 2.6e-06 27.5 0.2 3.9e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease DUF3396 PF11876.8 AAG04210.1 - 3.4e-64 216.1 0.0 4.2e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3396) VRR_NUC PF08774.11 AAG04211.1 - 1.2e-06 28.6 0.1 2.3e-06 27.7 0.1 1.6 1 1 1 2 2 2 1 VRR-NUC domain PAAR_motif PF05488.13 AAG04213.1 - 7.2e-21 74.1 8.9 2.7e-16 59.5 1.5 3.0 1 1 2 3 3 3 3 PAAR motif DUF4150 PF13665.6 AAG04213.1 - 0.006 16.7 0.0 4 7.6 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4150) TM2 PF05154.16 AAG04214.1 - 5.2e-19 68.3 16.3 2.8e-18 66.0 16.3 1.9 1 1 0 1 1 1 1 TM2 domain SBF_like PF13593.6 AAG04214.1 - 0.038 13.3 0.5 0.047 13.0 0.5 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) Adenyl_transf PF04439.12 AAG04215.1 - 0.013 14.6 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Longin PF13774.6 AAG04215.1 - 0.23 11.5 1.7 9.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Regulated-SNARE-like domain TetR_N PF00440.23 AAG04217.1 - 6e-10 38.8 0.2 1.2e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 AAG04217.1 - 0.003 17.6 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Ribosomal_L20 PF00453.18 AAG04217.1 - 0.019 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 HTH_7 PF02796.15 AAG04217.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF3268 PF11672.8 AAG04217.1 - 0.17 12.3 0.1 15 5.9 0.0 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain Abhydrolase_1 PF00561.20 AAG04218.1 - 1.3e-22 80.6 0.0 1.7e-16 60.6 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG04218.1 - 3.4e-18 67.1 1.2 5.1e-18 66.5 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG04218.1 - 2.7e-13 49.7 0.0 6.6e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAG04218.1 - 0.00021 20.1 0.0 0.00028 19.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 AAG04218.1 - 0.0039 16.9 0.8 0.038 13.6 0.0 2.5 3 0 0 3 3 3 1 Putative esterase Thioesterase PF00975.20 AAG04218.1 - 0.029 14.5 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 AAG04218.1 - 0.24 10.9 0.0 1.1 8.7 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Metal_hydrol PF10118.9 AAG04219.1 - 1.1e-88 297.2 0.9 1.2e-88 297.0 0.9 1.0 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase Arabinose_bd PF12625.7 AAG04220.1 - 2.9e-40 138.4 3.7 2.9e-40 138.4 3.7 1.5 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG04220.1 - 5.9e-19 68.1 0.6 5.9e-19 68.1 0.6 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04220.1 - 1.6e-09 37.6 0.1 3.1e-06 27.1 0.0 3.1 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family Lactamase_B PF00753.27 AAG04221.1 - 7e-30 104.5 1.0 8.1e-30 104.3 1.0 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG04221.1 - 0.0037 16.8 0.8 0.011 15.3 0.8 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_5 PF14597.6 AAG04221.1 - 0.0083 15.6 0.0 0.043 13.3 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily OmpA PF00691.20 AAG04222.1 - 9.4e-24 83.6 0.2 1.5e-23 83.0 0.2 1.3 1 0 0 1 1 1 1 OmpA family Gly-zipper_Omp PF13488.6 AAG04222.1 - 1.4e-08 34.6 18.0 3.5e-08 33.3 18.0 1.7 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 AAG04222.1 - 3e-05 23.7 19.7 6.2e-05 22.6 19.7 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF3482 PF11981.8 AAG04222.1 - 0.0023 17.4 9.7 0.0044 16.5 9.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3482) Rick_17kDa_Anti PF05433.15 AAG04222.1 - 0.0047 16.8 21.7 0.0047 16.8 21.7 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain Pilus_CpaD PF09476.10 AAG04222.1 - 0.011 15.5 1.3 0.26 11.0 0.0 2.4 2 1 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) MucB_RseB PF03888.14 AAG04222.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 MucB/RseB N-terminal domain Gly-zipper_OmpA PF13436.6 AAG04222.1 - 0.031 14.1 19.6 0.081 12.7 19.6 1.8 1 0 0 1 1 1 0 Glycine-zipper domain ETRAMP PF09716.10 AAG04222.1 - 0.76 9.9 2.2 4.4 7.4 0.8 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MLTD_N PF06474.12 AAG04222.1 - 1.9 8.7 5.0 6.1 7.1 5.0 1.8 1 0 0 1 1 1 0 MltD lipid attachment motif Acyltransferase PF01553.21 AAG04223.1 - 2e-14 53.4 0.0 2.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 AAG04223.1 - 0.0046 17.0 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus PTA_PTB PF01515.19 AAG04224.1 - 4.7e-118 394.1 0.5 6.8e-118 393.6 0.5 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 AAG04224.1 - 1.2e-37 129.7 0.0 9e-37 126.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DRTGG PF07085.12 AAG04224.1 - 6.4e-32 109.5 0.0 2.6e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 DRTGG domain CbiA PF01656.23 AAG04224.1 - 3.4e-06 27.1 0.0 1.7e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Acetate_kinase PF00871.17 AAG04225.1 - 3.9e-133 443.9 0.0 4.4e-133 443.8 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family ROK PF00480.20 AAG04225.1 - 0.05 13.1 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 ROK family FKBP_C PF00254.28 AAG04226.1 - 5.8e-11 42.6 0.0 9e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GSHPx PF00255.19 AAG04227.1 - 3.5e-38 129.5 0.0 4.2e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AAG04227.1 - 8.8e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG04227.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin TetR_C_13 PF16925.5 AAG04228.1 - 1.6e-18 66.7 0.0 2.7e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAG04228.1 - 4.1e-14 52.1 0.1 8.5e-14 51.1 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AAG04228.1 - 0.00057 20.2 0.9 0.0035 17.6 0.1 2.1 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 AAG04228.1 - 0.094 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Oxidored_FMN PF00724.20 AAG04229.1 - 3.8e-72 243.4 0.0 2.1e-66 224.5 0.0 2.0 1 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DegV PF02645.16 AAG04230.1 - 1.8e-77 260.5 0.0 2e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Glyco_transf_4 PF13439.6 AAG04231.1 - 4e-28 98.5 1.1 8.9e-28 97.4 0.1 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAG04231.1 - 1.9e-23 82.9 0.0 3e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG04231.1 - 5.5e-23 81.9 0.0 9.3e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAG04231.1 - 3.2e-16 60.2 5.0 3.2e-16 60.2 5.0 2.4 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAG04231.1 - 6.4e-08 32.9 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AAG04231.1 - 2e-05 24.6 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 AAG04231.1 - 0.035 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Peripla_BP_6 PF13458.6 AAG04231.1 - 0.097 12.3 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein DRE2_N PF16803.5 AAG04232.1 - 0.12 12.7 0.3 0.17 12.2 0.3 1.3 1 1 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Phosphoesterase PF04185.14 AAG04233.1 - 2.9e-125 418.1 1.6 4e-125 417.7 1.6 1.2 1 0 0 1 1 1 1 Phosphoesterase family DUF756 PF05506.12 AAG04233.1 - 1.8e-34 118.5 3.9 1.8e-17 64.0 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF756) TAT_signal PF10518.9 AAG04233.1 - 0.28 11.1 0.9 0.56 10.1 0.9 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Ceramidase_alk PF04734.13 AAG04234.1 - 6.9e-176 585.8 0.1 9e-175 582.1 0.1 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 AAG04234.1 - 3.7e-48 163.6 0.1 6.9e-48 162.7 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Taeniidae_ag PF05596.11 AAG04234.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Taeniidae antigen EI24 PF07264.11 AAG04235.1 - 3.6e-36 125.0 24.0 4.2e-36 124.9 24.0 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF1129 PF06570.11 AAG04235.1 - 3.1 7.2 15.0 0.29 10.6 4.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) GGDEF PF00990.21 AAG04236.1 - 1.5e-45 154.8 0.0 3.4e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE4 PF05228.13 AAG04236.1 - 2.5e-28 99.0 0.1 5.1e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 CHASE4 domain PAS PF00989.25 AAG04236.1 - 4.8e-16 58.8 0.0 1.2e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAG04236.1 - 7.6e-16 58.3 0.1 3e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAG04236.1 - 8.3e-14 51.7 0.0 1.8e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AAG04236.1 - 1.1e-09 38.5 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold HAMP PF00672.25 AAG04236.1 - 9.5e-08 32.3 0.6 9.5e-08 32.3 0.6 2.5 3 0 0 3 3 3 1 HAMP domain PAS_8 PF13188.7 AAG04236.1 - 7.6e-06 25.8 0.0 0.00014 21.8 0.0 2.8 2 0 0 2 2 2 1 PAS domain GGDEF_2 PF17853.1 AAG04236.1 - 0.06 13.6 0.3 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 GGDEF-like domain PAS_11 PF14598.6 AAG04236.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain AhpC-TSA PF00578.21 AAG04237.1 - 7.6e-34 116.3 0.0 1e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG04237.1 - 1.5e-17 63.7 0.0 1.9e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AAG04237.1 - 7.9e-13 48.0 0.0 1.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Pyr_redox_2 PF07992.14 AAG04238.1 - 2.8e-53 181.1 3.6 3.2e-53 180.9 3.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG04238.1 - 5.6e-24 84.9 0.1 2.5e-20 73.0 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG04238.1 - 2.1e-17 63.4 4.7 9.9e-17 61.3 1.9 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG04238.1 - 5.6e-06 25.7 5.1 0.0026 16.9 0.1 3.4 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 AAG04238.1 - 7.7e-06 24.9 2.0 0.045 12.5 0.2 4.2 4 1 1 5 5 5 2 HI0933-like protein FAD_oxidored PF12831.7 AAG04238.1 - 3.6e-05 23.3 3.4 0.0002 20.8 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG04238.1 - 0.00019 20.6 13.8 0.00069 18.8 0.3 4.1 2 2 3 5 5 5 2 FAD binding domain NAD_binding_8 PF13450.6 AAG04238.1 - 0.001 19.3 0.1 0.0031 17.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 AAG04238.1 - 0.0012 19.2 0.1 0.017 15.6 0.1 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 AAG04238.1 - 0.0012 18.5 7.6 1.3 8.5 0.0 3.8 2 2 2 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 AAG04238.1 - 0.0023 17.2 0.6 0.032 13.5 0.0 2.4 2 1 1 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.21 AAG04238.1 - 0.0027 17.0 0.5 0.4 9.9 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 AAG04238.1 - 0.019 14.1 0.0 0.087 12.0 0.0 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 AAG04238.1 - 0.031 14.3 0.8 1.2 9.2 0.1 2.9 4 0 0 4 4 3 0 Shikimate / quinate 5-dehydrogenase Hema_HEFG PF02710.14 AAG04238.1 - 0.09 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Trp_halogenase PF04820.14 AAG04238.1 - 0.14 11.0 0.8 2.8 6.7 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 AAG04238.1 - 0.16 11.2 4.5 2.6 7.2 0.3 3.2 2 2 1 3 3 3 0 FAD binding domain MAPEG PF01124.18 AAG04239.1 - 2.2e-21 76.1 10.5 2.5e-21 76.0 10.5 1.0 1 0 0 1 1 1 1 MAPEG family PALP PF00291.25 AAG04240.1 - 4.7e-64 216.6 0.9 5.3e-64 216.4 0.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LPMO_10 PF03067.15 AAG04241.1 - 8.7e-45 153.8 0.1 1.4e-44 153.1 0.1 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GbpA_2 PF18416.1 AAG04241.1 - 5.5e-27 94.0 0.5 8.7e-27 93.4 0.5 1.3 1 0 0 1 1 1 1 N-acetylglucosamine binding protein domain 2 YscW PF09619.10 AAG04241.1 - 0.031 14.6 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) DUF4912 PF16258.5 AAG04241.1 - 0.2 11.9 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) Flavodoxin_2 PF02525.17 AAG04242.1 - 3e-32 111.9 0.0 3.4e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAG04242.1 - 8.6e-17 61.3 0.0 1.1e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Lyase_1 PF00206.20 AAG04243.1 - 4.4e-106 354.8 0.0 5.4e-106 354.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AAG04243.1 - 8.5e-27 93.3 0.1 2.1e-26 92.1 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus DUF2804 PF10974.8 AAG04244.1 - 3.2e-76 257.0 0.0 3.6e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) DUF2059 PF09832.9 AAG04245.1 - 1.9e-21 75.9 1.8 5e-21 74.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2059) MRP-S27 PF10037.9 AAG04245.1 - 0.027 13.3 1.0 0.031 13.1 1.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 ATP-synt_G PF04718.15 AAG04245.1 - 0.043 14.6 3.2 0.1 13.4 1.1 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit Poxvirus_B22R_N PF13169.6 AAG04245.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal BolA PF01722.18 AAG04246.1 - 8e-24 83.7 0.2 1e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein UPF0176_N PF17773.1 AAG04247.1 - 3.8e-26 91.3 0.0 6.1e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 AAG04247.1 - 1.9e-07 31.6 0.0 5.9e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Rhodanese_C PF12368.8 AAG04247.1 - 6.3e-06 26.5 0.8 1.3e-05 25.5 0.8 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal zinc_ribbon_9 PF14369.6 AAG04247.1 - 0.0097 16.1 4.9 0.027 14.7 4.9 1.7 1 0 0 1 1 1 1 zinc-ribbon Acylphosphatase PF00708.18 AAG04247.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase Cys_rich_CPXG PF14255.6 AAG04247.1 - 0.084 12.8 0.4 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Cysteine-rich CPXCG DSBA PF01323.20 AAG04248.1 - 1.5e-13 50.9 0.0 1.9e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 AAG04248.1 - 2.3e-06 27.4 0.0 2.8e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 AAG04248.1 - 0.00017 21.8 0.0 0.00023 21.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAG04248.1 - 0.077 13.4 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain ABC_tran PF00005.27 AAG04249.1 - 2.3e-31 109.1 0.0 4.9e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAG04249.1 - 6.7e-29 101.4 2.6 8.5e-29 101.1 2.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAG04249.1 - 0.001 18.5 0.0 0.041 13.3 0.0 1.8 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG04249.1 - 0.0021 18.5 4.7 0.0031 17.9 2.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG04249.1 - 0.0049 16.8 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 AAG04249.1 - 0.024 14.9 0.1 0.087 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAG04249.1 - 0.029 14.1 0.1 0.07 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 AAG04249.1 - 0.037 13.8 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 AAG04249.1 - 0.082 12.5 2.9 0.97 9.0 2.9 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAG04249.1 - 0.1 12.6 0.4 0.8 9.7 0.2 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAG04249.1 - 0.1 12.8 0.3 0.8 10.0 0.3 2.3 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAG04249.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_membrane_3 PF13748.6 AAG04249.1 - 0.19 10.9 2.2 2.9 7.1 0.1 2.7 3 0 0 3 3 3 0 ABC transporter transmembrane region EAL PF00563.20 AAG04250.1 - 4.1e-63 213.1 0.0 8.1e-63 212.1 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG04250.1 - 8.2e-46 155.7 0.1 2.5e-45 154.1 0.0 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AAG04250.1 - 1.9e-11 43.9 0.0 4.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAG04250.1 - 7.2e-08 32.7 0.0 2.6e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG04250.1 - 1.9e-06 28.1 0.0 4.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAG04250.1 - 0.0004 20.3 0.1 0.0064 16.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain GGDEF_2 PF17853.1 AAG04250.1 - 0.0015 18.8 0.5 0.0067 16.7 0.0 2.4 2 0 0 2 2 2 1 GGDEF-like domain LPP PF04728.13 AAG04250.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Haem_oxygenas_2 PF14518.6 AAG04251.1 - 2.1e-14 53.7 1.3 2.7e-14 53.3 1.3 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme TENA_THI-4 PF03070.16 AAG04251.1 - 1.4e-08 34.8 0.7 5.6e-08 32.8 0.2 1.8 2 0 0 2 2 2 1 TENA/THI-4/PQQC family ADH_zinc_N PF00107.26 AAG04252.1 - 8.1e-13 48.5 0.5 1.2e-12 47.9 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG04252.1 - 1.7e-05 24.7 0.0 8.7e-05 22.4 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 AAG04252.1 - 0.024 14.5 1.4 0.034 14.0 1.4 1.2 1 0 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 AAG04252.1 - 0.063 12.6 0.1 0.099 12.0 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAG04252.1 - 0.17 11.1 2.1 0.26 10.6 2.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 AAG04252.1 - 0.21 11.0 0.1 0.29 10.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HTH_18 PF12833.7 AAG04253.1 - 4.6e-21 74.9 0.2 8.8e-21 74.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04253.1 - 6.6e-14 51.6 0.0 1.1e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG04253.1 - 1.8e-07 31.1 0.1 3.7e-07 30.1 0.1 1.6 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG04253.1 - 0.00067 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_23 PF13384.6 AAG04253.1 - 0.044 13.6 0.0 4.1 7.3 0.0 2.6 1 1 1 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 AAG04253.1 - 0.056 13.6 0.0 0.75 10.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Med12 PF09497.10 AAG04253.1 - 0.12 12.7 0.2 0.79 10.1 0.2 2.3 1 1 0 1 1 1 0 Transcription mediator complex subunit Med12 Glyoxalase_5 PF14696.6 AAG04254.1 - 1.1e-53 181.1 0.1 8.8e-52 175.0 0.1 2.1 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.25 AAG04254.1 - 9.7e-18 64.6 0.1 2.2e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG04254.1 - 1.1e-12 48.1 0.0 5.9e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAG04254.1 - 3e-05 24.2 0.0 0.017 15.3 0.0 2.5 3 0 0 3 3 3 2 Glyoxalase-like domain AA_permease PF00324.21 AAG04255.1 - 2.8e-114 382.3 42.8 3.5e-114 382.0 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG04255.1 - 2.6e-41 141.9 44.3 3.3e-41 141.5 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease OSTbeta PF15048.6 AAG04255.1 - 4.1 7.6 4.5 16 5.7 0.2 2.8 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein MliC PF09864.9 AAG04256.1 - 9.5e-22 76.7 0.8 2.1e-21 75.6 0.5 1.6 2 0 0 2 2 2 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme PCC_BT PF18140.1 AAG04256.1 - 0.13 12.6 0.0 0.62 10.4 0.0 1.9 1 1 1 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain RF-1 PF00472.20 AAG04257.1 - 5e-26 90.9 0.9 6.1e-26 90.6 0.9 1.0 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 AAG04257.1 - 0.039 14.4 0.0 0.046 14.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein DUF3499 PF12005.8 AAG04257.1 - 0.085 13.5 0.4 0.12 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Peptidase_S11 PF00768.20 AAG04258.1 - 8e-89 297.2 0.0 9.7e-89 296.9 0.0 1.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AAG04258.1 - 5.7e-12 45.7 0.1 9.5e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 AAG04258.1 - 4.1e-06 26.3 0.4 0.023 13.9 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S13 PF02113.15 AAG04258.1 - 4.3e-05 22.4 0.4 0.046 12.4 0.0 2.1 2 0 0 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Flg_bbr_C PF06429.13 AAG04258.1 - 0.04 14.1 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal Aminotran_1_2 PF00155.21 AAG04259.1 - 1.9e-80 270.8 0.0 2.1e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pterin_4a PF01329.19 AAG04260.1 - 5.7e-28 96.9 0.0 6.8e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Biopterin_H PF00351.21 AAG04261.1 - 1.2e-46 159.3 0.0 1.4e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Sigma54_activat PF00158.26 AAG04262.1 - 1.1e-58 197.7 0.0 1.9e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG04262.1 - 3.8e-18 65.9 0.0 7.4e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_50 PF18024.1 AAG04262.1 - 2e-16 59.3 0.0 7.2e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain ACT PF01842.25 AAG04262.1 - 8.2e-09 35.1 0.0 2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain PAS PF00989.25 AAG04262.1 - 6.7e-07 29.3 0.0 1.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAG04262.1 - 9.6e-07 28.7 0.1 3.4e-06 27.0 0.1 2.0 1 0 0 1 1 1 1 PAS domain ACT_4 PF13291.6 AAG04262.1 - 0.00018 22.0 0.0 0.0008 20.0 0.0 2.1 1 1 0 1 1 1 1 ACT domain AAA_5 PF07728.14 AAG04262.1 - 0.0073 16.3 0.0 0.026 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PAS_4 PF08448.10 AAG04262.1 - 0.0081 16.4 0.1 0.034 14.4 0.0 2.2 2 1 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAG04262.1 - 0.013 15.8 0.0 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 PAS domain HTH_38 PF13936.6 AAG04262.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MLTR_LBD PF17765.1 AAG04262.1 - 0.12 12.5 1.8 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain DUF2790 PF10976.8 AAG04263.1 - 2.7e-34 117.0 0.3 3.1e-34 116.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2790) FUSC PF04632.12 AAG04264.1 - 4.6e-212 706.1 39.7 5.2e-212 706.0 39.7 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAG04264.1 - 1.7e-14 54.0 31.9 1.9e-11 44.2 13.3 2.7 2 1 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AAG04264.1 - 0.00039 20.6 6.8 0.00039 20.6 6.8 2.3 2 1 0 2 2 2 1 Aromatic acid exporter family member 1 ALMT PF11744.8 AAG04264.1 - 0.0025 16.7 5.1 0.0039 16.1 5.1 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter CHASE6_C PF17150.4 AAG04264.1 - 0.005 17.5 0.1 0.017 15.8 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of two-partite extracellular sensor domain HRG PF16954.5 AAG04264.1 - 0.98 9.9 7.2 0.13 12.6 1.1 3.0 2 1 1 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF2390 PF09523.10 AAG04264.1 - 1 9.7 4.9 0.66 10.3 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2390) Na_Pi_cotrans PF02690.15 AAG04264.1 - 2.8 8.0 8.9 0.72 10.0 3.0 2.5 2 0 0 2 2 2 0 Na+/Pi-cotransporter LysR_substrate PF03466.20 AAG04265.1 - 5.8e-38 130.4 0.0 8.7e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04265.1 - 3.1e-20 71.9 4.3 5e-20 71.2 4.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG04265.1 - 0.0057 16.5 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 MarR family DUF503 PF04456.12 AAG04265.1 - 0.18 11.7 0.0 1 9.2 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF503) LysR_substrate PF03466.20 AAG04266.1 - 6.8e-43 146.5 4.0 9.8e-43 145.9 4.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04266.1 - 1.3e-17 63.5 0.6 3.3e-17 62.2 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SBP_bac_11 PF13531.6 AAG04266.1 - 0.016 14.9 0.0 0.047 13.4 0.0 1.9 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein MaoC_dehydrat_N PF13452.6 AAG04267.1 - 5.5e-09 36.2 0.0 1.5e-08 34.9 0.0 1.7 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Acyl-CoA_dh_1 PF00441.24 AAG04268.1 - 6.2e-34 117.4 0.4 8.9e-34 116.9 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG04268.1 - 2e-25 89.7 0.1 4.7e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG04268.1 - 1.5e-21 76.4 0.1 2.7e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG04268.1 - 2.9e-13 50.2 0.8 5.3e-13 49.4 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Phage_attach PF05354.11 AAG04268.1 - 0.072 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Phage Head-Tail Attachment Glyoxalase PF00903.25 AAG04269.1 - 5.4e-10 39.6 0.0 3e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AAG04269.1 - 0.00014 21.7 0.0 0.00041 20.3 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AAG04269.1 - 0.00041 20.5 0.2 0.004 17.3 0.2 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAG04269.1 - 0.00074 19.8 0.0 0.0034 17.6 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG04269.1 - 0.16 12.8 0.0 0.21 12.4 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain MmgE_PrpD PF03972.14 AAG04270.1 - 4.3e-137 457.3 7.3 4.8e-137 457.1 7.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family CoA_transf_3 PF02515.17 AAG04271.1 - 2.4e-111 372.4 0.0 2.7e-111 372.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III RisS_PPD PF16524.5 AAG04271.1 - 0.099 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS HpcH_HpaI PF03328.14 AAG04272.1 - 8.8e-30 103.5 0.3 5.9e-29 100.8 0.3 2.0 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AAG04272.1 - 4e-11 42.7 0.0 4e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DctP PF03480.13 AAG04273.1 - 1.6e-106 355.8 0.2 1.8e-106 355.7 0.2 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Nnf1 PF03980.14 AAG04273.1 - 0.015 15.7 0.1 0.031 14.6 0.1 1.5 1 0 0 1 1 1 0 Nnf1 Metal_resist PF13801.6 AAG04273.1 - 0.083 13.1 5.9 0.36 11.0 0.2 3.0 2 1 1 3 3 3 0 Heavy-metal resistance DctQ PF04290.12 AAG04274.1 - 3.4e-20 72.3 10.7 3.4e-20 72.3 10.7 1.9 1 1 1 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component Abhydrolase_9_N PF15420.6 AAG04274.1 - 0.15 12.1 8.2 0.11 12.5 2.8 2.5 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus KaiB PF07689.12 AAG04274.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 KaiB domain DctM PF06808.12 AAG04275.1 - 2e-123 412.3 54.7 2.3e-123 412.1 54.7 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component FAM176 PF14851.6 AAG04275.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 FAM176 family CitMHS PF03600.16 AAG04275.1 - 7 5.7 66.8 0.86 8.7 31.5 2.3 1 1 1 2 2 2 0 Citrate transporter AMP-binding PF00501.28 AAG04276.1 - 7.9e-93 311.3 0.1 1e-92 311.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG04276.1 - 9.7e-26 90.6 0.1 2e-25 89.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAG04276.1 - 1.3e-22 79.4 0.6 3e-22 78.3 0.6 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus SBP_bac_3 PF00497.20 AAG04277.1 - 2.3e-66 223.4 0.2 2.7e-66 223.3 0.2 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG04277.1 - 4.5e-08 33.3 0.0 1.1e-07 32.0 0.0 1.7 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAG04277.1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.7 1 1 1 2 2 2 1 NMT1/THI5 like BPD_transp_1 PF00528.22 AAG04278.1 - 1.9e-22 79.9 7.3 2.4e-22 79.6 7.3 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF1516 PF07457.11 AAG04278.1 - 0.053 13.7 0.1 0.053 13.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) CM2 PF03021.14 AAG04278.1 - 0.11 12.3 0.9 0.19 11.5 0.3 1.7 2 0 0 2 2 2 0 Influenza C virus M2 protein MitoNEET_N PF10660.9 AAG04278.1 - 0.21 11.6 3.1 4.9 7.3 0.0 3.4 3 1 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus BPD_transp_1 PF00528.22 AAG04279.1 - 1.2e-15 57.8 10.3 1.2e-15 57.7 9.8 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component AstE_AspA PF04952.14 AAG04280.1 - 7.6e-27 94.1 0.0 8.3e-16 57.9 0.0 2.1 1 1 1 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family HlyD_3 PF13437.6 AAG04280.1 - 0.0023 18.6 0.0 0.0062 17.2 0.0 1.7 1 0 0 1 1 1 1 HlyD family secretion protein Peptidase_M14 PF00246.24 AAG04280.1 - 0.048 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase ABC_tran PF00005.27 AAG04281.1 - 3.8e-33 114.9 0.0 5.7e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG04281.1 - 4.4e-12 46.4 0.1 2.5e-06 27.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG04281.1 - 5.7e-07 29.2 0.5 4.1e-06 26.4 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AAG04281.1 - 0.00035 19.4 0.0 0.094 11.3 0.0 2.0 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.6 AAG04281.1 - 0.00068 19.3 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAG04281.1 - 0.0061 16.3 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 AAG04281.1 - 0.011 14.6 0.2 4.1 6.1 0.1 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAG04281.1 - 0.011 16.2 0.2 0.024 15.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 AAG04281.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 AAG04281.1 - 0.017 15.3 0.0 0.063 13.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAG04281.1 - 0.019 15.5 0.1 0.033 14.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAG04281.1 - 0.027 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Mg_chelatase PF01078.21 AAG04281.1 - 0.046 13.1 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AAG04281.1 - 0.053 13.4 0.1 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 AAG04281.1 - 0.055 13.7 0.1 0.083 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAG04281.1 - 0.078 13.3 0.1 0.15 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG04281.1 - 0.13 12.5 0.1 2.2 8.6 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 AAG04281.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain HTH_18 PF12833.7 AAG04282.1 - 4.2e-24 84.6 0.1 9.1e-24 83.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04282.1 - 8.7e-18 63.9 0.1 6.1e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 AAG04282.1 - 0.0009 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_23 PF13384.6 AAG04282.1 - 0.0018 18.0 0.0 0.0063 16.3 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 AAG04282.1 - 0.052 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAG04282.1 - 0.081 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Aminotran_3 PF00202.21 AAG04284.1 - 7e-126 420.1 0.0 8e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAG04284.1 - 1e-06 28.2 0.0 1.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II AstA PF04958.12 AAG04285.1 - 6.6e-127 422.7 0.0 7.4e-127 422.5 0.0 1.0 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit AstA PF04958.12 AAG04286.1 - 1.1e-137 458.2 0.0 1.2e-137 458.0 0.0 1.0 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Aldedh PF00171.22 AAG04287.1 - 9.2e-124 413.4 0.0 1.1e-123 413.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AstB PF04996.12 AAG04288.1 - 5.2e-225 747.2 0.1 5.8e-225 747.0 0.1 1.0 1 0 0 1 1 1 1 Succinylarginine dihydrolase AstE_AspA PF04952.14 AAG04290.1 - 1.1e-76 257.7 0.0 1.3e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.24 AAG04290.1 - 0.012 15.4 0.1 4.6 7.0 0.0 2.3 2 1 1 3 3 3 0 Zinc carboxypeptidase Beta_elim_lyase PF01212.21 AAG04291.1 - 1.3e-94 316.8 0.3 1.7e-94 316.4 0.3 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AAG04291.1 - 7.8e-08 31.9 0.0 9.5e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAG04291.1 - 4e-06 26.4 0.1 0.00046 19.6 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAG04291.1 - 0.13 10.8 0.0 0.24 9.9 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme tRNA-synt_2c PF01411.19 AAG04292.1 - 1.7e-228 759.6 0.0 2.2e-228 759.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 AAG04292.1 - 4.6e-28 98.4 9.0 1.1e-27 97.1 9.0 1.7 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 AAG04292.1 - 1.4e-19 69.9 0.5 4.6e-19 68.2 0.5 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CorA PF01544.18 AAG04292.1 - 0.008 15.5 0.4 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Peptidase_M20 PF01546.28 AAG04292.1 - 0.51 10.0 2.6 1.3 8.6 1.0 2.4 2 1 0 2 2 2 0 Peptidase family M20/M25/M40 HALZ PF02183.18 AAG04292.1 - 5.3 7.4 7.5 1.3 9.3 3.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper AA_kinase PF00696.28 AAG04293.1 - 3.6e-49 167.5 3.0 6.1e-49 166.8 3.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 AAG04293.1 - 1.6e-19 69.4 0.6 1.9e-15 56.4 0.4 2.9 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AAG04293.1 - 3e-18 65.3 2.3 3.1e-10 39.6 0.1 3.2 3 0 0 3 3 3 2 ACT domain DUF3335 PF11814.8 AAG04293.1 - 0.049 13.1 0.6 0.23 10.9 0.0 2.3 3 0 0 3 3 3 0 Peptidase_C39 like family NAD_binding_7 PF13241.6 AAG04293.1 - 0.087 13.3 0.5 3.1 8.3 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding CsrA PF02599.16 AAG04294.1 - 8.7e-27 92.8 1.4 9.8e-27 92.7 1.4 1.0 1 0 0 1 1 1 1 Global regulator protein family S1 PF00575.23 AAG04294.1 - 0.037 14.4 0.9 0.13 12.7 0.7 1.8 1 1 1 2 2 2 0 S1 RNA binding domain Peptidase_S24 PF00717.23 AAG04295.1 - 1e-12 47.8 0.0 1.5e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HTH_3 PF01381.22 AAG04295.1 - 5.4e-11 42.4 0.0 1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAG04295.1 - 2e-09 37.7 0.1 5.7e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG04295.1 - 9.5e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAG04295.1 - 1.1e-05 25.2 0.2 2.9e-05 23.9 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Phage_CI_C PF16452.5 AAG04295.1 - 0.005 17.1 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 Bacteriophage CI repressor C-terminal domain HTH_24 PF13412.6 AAG04295.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_CI_repr PF07022.13 AAG04295.1 - 0.025 14.7 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain YdaS_antitoxin PF15943.5 AAG04295.1 - 0.029 14.2 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR PF00376.23 AAG04296.1 - 0.0025 17.6 0.1 0.0047 16.7 0.1 1.4 1 0 0 1 1 1 1 MerR family regulatory protein HTH_IclR PF09339.10 AAG04296.1 - 0.0061 16.3 0.9 0.013 15.2 0.1 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_28 PF13518.6 AAG04296.1 - 0.015 15.4 1.3 0.021 14.9 0.3 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AAG04296.1 - 0.023 14.6 0.2 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 MarR family MerR_1 PF13411.6 AAG04296.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein Phage_holin_8 PF16931.5 AAG04297.1 - 9e-36 122.6 5.8 1e-35 122.4 5.8 1.0 1 0 0 1 1 1 1 Putative phage holin Phage_holin_3_7 PF05449.11 AAG04298.1 - 1.6e-26 92.1 7.1 1.8e-26 92.0 7.1 1.0 1 0 0 1 1 1 1 Putative 3TM holin, Phage_holin_3 DUF5360 PF17314.2 AAG04298.1 - 0.083 13.0 0.2 0.098 12.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5360) DUF4124 PF13511.6 AAG04301.1 - 3.6e-10 40.0 0.2 7.7e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) SmpA_OmlA PF04355.13 AAG04301.1 - 9.2e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 SmpA / OmlA family MgtE PF01769.16 AAG04302.1 - 1.4e-26 93.3 5.2 1.4e-26 93.3 5.2 1.6 2 0 0 2 2 2 1 Divalent cation transporter MgtE_N PF03448.17 AAG04302.1 - 3.3e-26 91.9 13.2 1.6e-25 89.7 9.4 2.6 2 0 0 2 2 2 1 MgtE intracellular N domain CBS PF00571.28 AAG04302.1 - 1.7e-13 50.8 2.4 9.5e-07 29.2 0.1 3.0 2 0 0 2 2 2 2 CBS domain F-box PF00646.33 AAG04302.1 - 0.047 13.6 0.3 4.9 7.1 0.1 2.4 2 0 0 2 2 2 0 F-box domain 5_3_exonuc PF01367.20 AAG04302.1 - 0.069 13.8 1.3 3.5 8.3 0.1 2.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF3487 PF11990.8 AAG04302.1 - 6.8 6.6 8.5 0.63 9.9 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) HTH_31 PF13560.6 AAG04303.1 - 0.0083 16.4 0.8 0.016 15.6 0.8 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1456 PF07308.13 AAG04304.1 - 9.2e-49 163.7 0.1 6.1e-25 87.3 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) Radical_SAM PF04055.21 AAG04305.1 - 2.7e-27 96.2 0.0 8.1e-27 94.6 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily TRAM_2 PF18693.1 AAG04305.1 - 8.1e-25 86.8 1.3 1.7e-24 85.7 1.3 1.6 1 0 0 1 1 1 1 TRAM domain UPF0004 PF00919.20 AAG04305.1 - 5.7e-21 74.4 0.1 1e-20 73.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AAG04305.1 - 7.1e-06 25.9 0.2 1.7e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 TRAM domain RNase_II_C_S1 PF18614.1 AAG04305.1 - 0.00072 19.5 0.5 0.005 16.8 0.1 2.2 2 0 0 2 2 2 1 RNase II-type exonuclease C-terminal S1 domain S1 PF00575.23 AAG04305.1 - 0.0011 19.2 0.5 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 S1 RNA binding domain CLP1_P PF16575.5 AAG04305.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TOBE PF03459.17 AAG04305.1 - 0.11 12.9 0.0 3.5 8.0 0.0 2.5 2 0 0 2 2 2 0 TOBE domain CSD2 PF17876.1 AAG04305.1 - 0.12 12.5 0.4 1.4 9.2 0.0 2.6 3 0 0 3 3 3 0 Cold shock domain K_trans PF02705.16 AAG04306.1 - 1.3e-205 683.9 19.8 1.5e-205 683.7 19.8 1.0 1 0 0 1 1 1 1 K+ potassium transporter Ni_hydr_CYTB PF01292.20 AAG04307.1 - 6.8e-25 87.7 7.7 7.8e-25 87.5 7.7 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 AAG04307.1 - 0.0024 18.0 1.7 0.066 13.4 1.1 2.3 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 VirJ PF06057.11 AAG04308.1 - 1.5e-81 272.9 0.0 2.2e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Cutinase PF01083.22 AAG04308.1 - 0.00069 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Cutinase Hydrolase_4 PF12146.8 AAG04308.1 - 0.019 14.3 0.0 0.094 12.0 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG04308.1 - 0.085 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 AAG04308.1 - 0.17 11.0 0.0 16 4.5 0.0 2.1 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF2156 PF09924.9 AAG04309.1 - 4.8e-93 311.4 0.1 6.9e-93 310.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) LPG_synthase_TM PF03706.13 AAG04309.1 - 1.2e-15 57.8 47.0 1.2e-15 57.8 47.0 3.7 1 1 3 4 4 4 1 Lysylphosphatidylglycerol synthase TM region Acetyltransf_6 PF13480.7 AAG04309.1 - 0.015 15.5 0.1 0.057 13.6 0.1 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATPase_gene1 PF09527.10 AAG04310.1 - 0.00089 19.4 1.7 0.00089 19.4 1.7 2.9 3 0 0 3 3 3 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter RPA_C PF08784.11 AAG04311.1 - 0.0052 17.4 0.1 0.0086 16.7 0.1 1.3 1 0 0 1 1 1 1 Replication protein A C terminal ParBc PF02195.18 AAG04311.1 - 0.032 14.5 0.0 0.073 13.4 0.0 1.7 1 1 0 1 1 1 0 ParB-like nuclease domain IMS PF00817.20 AAG04312.1 - 9.8e-53 178.2 0.0 1.5e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family DNA_pol_lambd_f PF10391.9 AAG04312.1 - 1e-06 28.4 0.0 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda IMS_HHH PF11798.8 AAG04312.1 - 2.3e-06 27.6 0.0 9.3e-06 25.7 0.0 2.2 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.8 AAG04312.1 - 8.5e-05 23.2 0.0 0.00019 22.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF1805 PF08827.11 AAG04312.1 - 0.028 14.7 0.1 2.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) HHH_5 PF14520.6 AAG04312.1 - 0.056 14.1 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Cdd1 PF11731.8 AAG04312.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus Sulfatase PF00884.23 AAG04313.1 - 2.1e-29 102.9 0.1 3.3e-29 102.3 0.1 1.3 1 1 0 1 1 1 1 Sulfatase DUF3413 PF11893.8 AAG04313.1 - 4.8e-20 71.8 0.1 4.7e-19 68.6 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3413) Phosphodiest PF01663.22 AAG04313.1 - 2.5e-07 30.7 0.0 1.2e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 AAG04313.1 - 5.8e-05 21.9 0.0 8.6e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 AAG04313.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) META PF03724.16 AAG04314.1 - 1.6e-27 95.6 0.0 2.1e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 META domain 2-Hacid_dh_C PF02826.19 AAG04316.1 - 1.8e-60 203.3 0.0 2.5e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAG04316.1 - 2.7e-32 111.2 0.0 3.1e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAG04316.1 - 1.4e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 AAG04316.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_33 PF10017.9 AAG04316.1 - 0.02 14.1 0.3 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent 3HCDH_N PF02737.18 AAG04316.1 - 0.027 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 AAG04316.1 - 0.13 11.9 0.0 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HATPase_c PF02518.26 AAG04317.1 - 1e-29 103.3 0.1 1.8e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAG04317.1 - 1.2e-29 102.7 1.0 1.2e-28 99.5 0.1 2.8 3 0 0 3 3 2 1 Response regulator receiver domain HisKA PF00512.25 AAG04317.1 - 4.4e-23 81.1 5.3 1.2e-21 76.5 0.1 4.5 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF2222 PF09984.9 AAG04317.1 - 1.2e-20 73.9 0.0 2.8e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) Hpt PF01627.23 AAG04317.1 - 5.7e-12 45.7 4.6 5.7e-12 45.7 4.6 3.1 2 0 0 2 2 2 1 Hpt domain HAMP PF00672.25 AAG04317.1 - 7.7e-10 39.0 0.6 3.2e-09 37.0 0.6 2.2 1 0 0 1 1 1 1 HAMP domain sCache_3_2 PF17203.4 AAG04317.1 - 0.0063 16.6 2.5 0.053 13.6 0.3 2.6 2 0 0 2 2 2 1 Single cache domain 3 ApoLp-III PF07464.11 AAG04317.1 - 0.011 15.9 2.7 3 7.9 0.4 3.4 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) HATPase_c_3 PF13589.6 AAG04317.1 - 0.039 13.8 0.8 0.06 13.2 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ThiP_synth PF10120.9 AAG04317.1 - 0.053 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Thiamine-phosphate synthase Syntaxin-6_N PF09177.11 AAG04317.1 - 0.72 10.4 7.0 1.5 9.4 1.6 3.0 3 0 0 3 3 2 0 Syntaxin 6, N-terminal BMFP PF04380.13 AAG04317.1 - 2.6 8.6 7.3 21 5.7 0.8 3.5 3 0 0 3 3 2 0 Membrane fusogenic activity Response_reg PF00072.24 AAG04318.1 - 1.9e-25 89.2 0.0 2.7e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG04318.1 - 2e-18 66.3 0.1 3.2e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HK_sensor PF16750.5 AAG04319.1 - 5.6e-36 123.2 0.2 3.3e-35 120.7 0.0 2.2 2 0 0 2 2 2 1 Sensor domain of 2-component histidine kinase HATPase_c PF02518.26 AAG04319.1 - 2.8e-14 53.6 0.0 5.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAG04319.1 - 1.8e-12 47.4 1.6 1.8e-12 47.4 1.6 2.6 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 AAG04319.1 - 2.4e-09 37.1 2.0 2.4e-09 37.1 2.0 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GNAT_acetyltr_2 PF13718.6 AAG04319.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 TonB_dep_Rec PF00593.24 AAG04320.1 - 5.2e-55 188.2 25.3 5.2e-55 188.2 25.3 1.6 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG04320.1 - 6.6e-30 103.9 0.5 2.2e-29 102.2 0.5 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Laterosporulin PF17861.1 AAG04320.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Laterosporulin defensin-like peptide PALP PF00291.25 AAG04321.1 - 1.8e-68 231.1 0.1 2.8e-68 230.5 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 AAG04321.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF374 PF04028.13 AAG04321.1 - 1 9.0 3.1 25 4.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF374) tRNA_U5-meth_tr PF05958.11 AAG04322.1 - 1.1e-25 90.3 0.0 4.9e-24 85.0 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 AAG04322.1 - 6.2e-10 39.1 0.0 9.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG04322.1 - 3.3e-09 37.3 0.0 9.1e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAG04322.1 - 6e-06 26.0 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AAG04322.1 - 7e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 AAG04322.1 - 0.00029 21.4 0.0 0.0009 19.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG04322.1 - 0.00053 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAG04322.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AAG04322.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 AAG04322.1 - 0.03 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.10 AAG04322.1 - 0.17 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HD_4 PF13328.6 AAG04323.1 - 5.1e-46 156.3 5.1 6.1e-46 156.0 3.2 2.0 2 0 0 2 2 2 1 HD domain RelA_SpoT PF04607.17 AAG04323.1 - 3.5e-38 130.5 0.0 7.8e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 AAG04323.1 - 4e-22 78.0 0.0 1e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AAG04323.1 - 9.4e-20 71.0 0.1 2.8e-19 69.5 0.1 1.9 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AAG04323.1 - 5.7e-05 22.8 0.1 0.00013 21.7 0.1 1.7 1 0 0 1 1 1 1 ACT domain MazG PF03819.17 AAG04324.1 - 2.6e-37 126.8 0.5 4.5e-26 90.8 0.0 2.5 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 AAG04324.1 - 2.2e-10 40.8 0.9 2.3e-05 24.8 0.1 2.6 2 0 0 2 2 2 2 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 AAG04324.1 - 0.0041 17.4 0.0 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 MazG-like family Asp_Arg_Hydrox PF05118.15 AAG04325.1 - 8.2e-47 158.9 0.0 1.2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 AAG04325.1 - 0.058 13.1 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Cupin domain DUF2058 PF09831.9 AAG04326.1 - 1.9e-61 207.2 20.1 2.2e-61 207.0 20.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2058) Spore_coat_CotO PF14153.6 AAG04326.1 - 0.23 11.4 13.3 0.33 10.8 13.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DDRGK PF09756.9 AAG04326.1 - 0.29 10.7 18.6 0.43 10.1 18.6 1.3 1 0 0 1 1 1 0 DDRGK domain DUF4661 PF15576.6 AAG04326.1 - 0.31 10.9 3.4 0.37 10.7 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Membralin PF09746.9 AAG04326.1 - 0.54 9.2 5.1 0.63 9.0 5.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein Gti1_Pac2 PF09729.9 AAG04326.1 - 1.1 9.3 7.1 1.4 9.0 7.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Ndc1_Nup PF09531.10 AAG04326.1 - 1.2 7.8 4.0 1.3 7.6 4.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 AAG04326.1 - 1.3 7.7 8.5 1.4 7.6 8.5 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 AAG04326.1 - 2.1 8.4 4.6 2.5 8.1 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4746 PF15928.5 AAG04326.1 - 2.3 7.6 9.8 3 7.2 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM60A PF15396.6 AAG04326.1 - 5 7.1 11.1 7.1 6.6 11.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 AAG04326.1 - 5.2 6.8 13.4 7.2 6.4 13.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 AAG04326.1 - 6.2 5.5 8.8 7.9 5.2 8.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Wzz PF02706.15 AAG04327.1 - 5.6e-14 52.2 0.4 5.6e-14 52.2 0.4 1.9 2 0 0 2 2 2 1 Chain length determinant protein GNVR PF13807.6 AAG04327.1 - 1.5e-09 37.6 0.3 1.5e-09 37.6 0.3 1.9 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Gp58 PF07902.11 AAG04327.1 - 0.2 9.9 1.2 0.3 9.3 1.2 1.2 1 0 0 1 1 1 0 gp58-like protein DUF1690 PF07956.11 AAG04327.1 - 0.66 10.4 8.7 0.42 11.0 1.0 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) ROF PF07073.12 AAG04328.1 - 3.9e-27 94.2 0.0 4.6e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Modulator of Rho-dependent transcription termination (ROF) DUF2024 PF09630.10 AAG04329.1 - 7e-30 102.7 0.0 7.6e-30 102.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Thioredoxin_3 PF13192.6 AAG04330.1 - 1.8e-07 31.1 0.0 2.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.24 AAG04330.1 - 6.1e-06 26.4 0.0 8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_4 PF13462.6 AAG04330.1 - 0.009 16.2 0.0 0.072 13.3 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin DUF836 PF05768.14 AAG04330.1 - 0.019 15.3 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 AAG04330.1 - 0.044 14.2 0.0 0.055 13.9 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1525 PF07511.11 AAG04330.1 - 0.083 13.0 0.1 0.096 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) TraF PF13728.6 AAG04330.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.0 1 0 0 1 1 1 0 F plasmid transfer operon protein MarR_2 PF12802.7 AAG04331.1 - 2.5e-09 36.9 0.1 5.7e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAG04331.1 - 6.5e-09 36.2 0.0 1.1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AAG04331.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 AAG04331.1 - 2.2e-05 24.2 0.0 4.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 AAG04331.1 - 0.00022 21.3 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 AAG04331.1 - 0.0033 17.2 0.0 0.02 14.7 0.0 2.1 1 1 1 2 2 2 1 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 AAG04331.1 - 0.0063 16.5 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain PadR PF03551.14 AAG04331.1 - 0.019 14.9 0.7 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family AphA_like PF14557.6 AAG04331.1 - 0.047 13.4 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Crp PF00325.20 AAG04331.1 - 0.087 12.5 1.2 0.27 10.9 0.4 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_1 PF00126.27 AAG04331.1 - 0.11 12.5 0.2 0.3 11.1 0.2 1.8 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family TrmB PF01978.19 AAG04331.1 - 0.13 12.2 0.2 0.24 11.3 0.0 1.6 2 0 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AAG04331.1 - 0.16 11.5 0.1 0.4 10.3 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3108 PF11306.8 AAG04332.1 - 1.3e-18 67.8 0.0 1.6e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3108) Formyl_trans_N PF00551.19 AAG04333.1 - 2.5e-66 222.9 0.0 2.9e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase CMD PF02627.20 AAG04333.1 - 0.023 14.8 0.2 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family AIRS_C PF02769.22 AAG04334.1 - 5.1e-39 133.9 0.1 8.3e-39 133.2 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AAG04334.1 - 1.7e-15 57.4 1.2 3.4e-15 56.5 1.2 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF2066 PF09839.9 AAG04335.1 - 2.3e-68 230.1 5.4 3.1e-68 229.7 5.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2066) DUF4253 PF14062.6 AAG04335.1 - 0.04 14.1 0.0 0.12 12.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4253) Bac_DnaA PF00308.18 AAG04336.1 - 9.7e-21 74.6 0.0 9.4e-20 71.4 0.0 1.9 1 1 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.17 AAG04336.1 - 0.0004 20.2 0.1 0.018 14.8 0.0 2.7 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 AAG04336.1 - 0.006 17.0 0.0 0.071 13.5 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 AAG04336.1 - 0.04 13.1 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 AAG04336.1 - 0.044 14.1 1.0 0.23 11.8 1.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAG04336.1 - 0.067 13.5 0.6 1.2 9.4 0.6 2.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAG04336.1 - 0.2 12.1 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF2069 PF09842.9 AAG04337.1 - 3e-31 107.7 11.6 3.6e-31 107.4 11.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2069) DUF2339 PF10101.9 AAG04337.1 - 0.13 10.8 14.9 0.16 10.5 14.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) FMN_red PF03358.15 AAG04338.1 - 1.3e-09 38.0 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 AAG04338.1 - 6.4e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 AAG04338.1 - 0.00023 21.4 0.0 0.0046 17.2 0.0 2.1 1 1 0 2 2 2 1 Flavodoxin domain Flavodoxin_2 PF02525.17 AAG04338.1 - 0.0067 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold ArsC PF03960.15 AAG04339.1 - 3.5e-19 68.6 0.0 4e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AAG04339.1 - 0.013 15.7 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin SAP PF02037.27 AAG04339.1 - 0.049 13.4 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 SAP domain Virul_fac_BrkB PF03631.15 AAG04340.1 - 4.4e-59 200.2 26.7 8.3e-59 199.3 26.1 1.6 2 0 0 2 2 2 1 Virulence factor BrkB AGH PF17558.2 AAG04340.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Androgenic gland hormone AhpC-TSA PF00578.21 AAG04342.1 - 4.1e-18 65.5 0.0 4.9e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG04342.1 - 1.1e-08 35.0 0.0 2.1e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 AAG04342.1 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 AAG04342.1 - 1e-05 25.7 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like SCO1-SenC PF02630.14 AAG04342.1 - 0.0066 16.4 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC GSHPx PF00255.19 AAG04342.1 - 0.084 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase Acylphosphatase PF00708.18 AAG04343.1 - 2.9e-24 85.3 0.1 3.2e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase DUF4880 PF16220.5 AAG04343.1 - 0.03 14.2 2.9 0.044 13.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Arabinose_Iso_C PF11762.8 AAG04343.1 - 0.14 12.0 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain DUF5061 PF16587.5 AAG04344.1 - 0.077 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein H-kinase_dim PF02895.14 AAG04344.1 - 0.14 12.6 0.3 0.28 11.6 0.3 1.7 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain tRNA-synt_2b PF00587.25 AAG04345.1 - 2.5e-52 177.5 0.0 3.4e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 AAG04345.1 - 2.9e-24 85.5 0.1 4.9e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 AAG04345.1 - 3.5e-16 59.1 0.0 6.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain 4HBT PF03061.22 AAG04346.1 - 5.2e-15 55.5 0.0 7.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AAG04346.1 - 0.0034 17.5 0.0 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AAG04346.1 - 0.016 15.5 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily OprD PF03573.13 AAG04347.1 - 6.1e-164 545.7 9.7 7e-164 545.5 9.7 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family HIT PF01230.23 AAG04348.1 - 4.2e-18 65.9 0.0 7.7e-18 65.1 0.0 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 AAG04348.1 - 0.046 14.2 0.0 0.067 13.7 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding SlyX PF04102.12 AAG04349.1 - 4.5e-24 84.8 0.7 5e-24 84.7 0.7 1.0 1 0 0 1 1 1 1 SlyX MscS_porin PF12795.7 AAG04349.1 - 0.00067 19.3 0.6 0.00069 19.2 0.6 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain CSD PF00313.22 AAG04350.1 - 7.1e-24 83.5 0.4 7.6e-24 83.4 0.4 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAG04350.1 - 0.00057 19.5 0.7 0.00082 19.0 0.7 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain Ferritin PF00210.24 AAG04351.1 - 3e-28 98.5 0.0 3.3e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain tRNA-synt_2 PF00152.20 AAG04352.1 - 1.6e-108 362.6 0.0 1.9e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 AAG04352.1 - 7.1e-32 109.5 0.0 1.4e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 AAG04352.1 - 8.5e-17 60.9 0.1 1.9e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AAG04352.1 - 2.5e-05 23.9 0.5 0.015 14.8 0.3 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Transcrip_reg PF01709.20 AAG04353.1 - 5.2e-94 314.2 0.4 5.8e-94 314.0 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator SBP_bac_3 PF00497.20 AAG04353.1 - 0.04 13.3 0.2 0.86 9.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 RuvC PF02075.17 AAG04354.1 - 5.9e-68 227.4 0.6 6.8e-68 227.2 0.6 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC MCR_beta_N PF02783.15 AAG04354.1 - 0.075 12.7 0.2 0.099 12.3 0.2 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain RuvA_N PF01330.21 AAG04355.1 - 2.3e-24 85.3 0.0 5e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 RuvA N terminal domain HHH_5 PF14520.6 AAG04355.1 - 1.2e-18 67.4 1.8 4.8e-18 65.5 0.1 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain RuvA_C PF07499.13 AAG04355.1 - 1.8e-15 57.1 0.4 1.8e-15 57.1 0.4 2.1 2 1 0 2 2 2 1 RuvA, C-terminal domain HHH PF00633.23 AAG04355.1 - 2.1e-08 33.6 0.7 0.0003 20.5 0.0 3.0 3 0 0 3 3 3 2 Helix-hairpin-helix motif Transposase_20 PF02371.16 AAG04355.1 - 0.00022 21.4 0.0 0.006 16.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 AAG04355.1 - 0.00063 19.9 0.1 0.024 15.0 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif HHH_8 PF14716.6 AAG04355.1 - 0.0073 16.7 0.7 0.61 10.5 0.0 3.1 2 1 1 3 3 3 1 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 AAG04355.1 - 0.01 16.4 0.0 0.2 12.3 0.0 2.3 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 AAG04355.1 - 0.03 14.4 0.0 1.3 9.1 0.0 2.7 2 1 1 3 3 2 0 Helix-hairpin-helix motif Cdd1 PF11731.8 AAG04355.1 - 0.035 14.3 0.0 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Pathogenicity locus HHH_3 PF12836.7 AAG04355.1 - 0.035 14.4 0.1 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 AAG04355.1 - 0.14 12.0 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda RuvB_N PF05496.12 AAG04356.1 - 2.9e-81 270.9 0.0 4.1e-81 270.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 AAG04356.1 - 2.1e-33 113.9 0.7 3.6e-33 113.1 0.7 1.4 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 AAG04356.1 - 5.1e-26 90.4 0.0 1.4e-25 89.0 0.0 1.8 2 0 0 2 2 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 AAG04356.1 - 1.6e-18 67.4 0.0 2.9e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAG04356.1 - 3.5e-07 30.3 0.0 0.0045 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AAG04356.1 - 0.00042 20.2 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAG04356.1 - 0.00046 20.5 0.2 0.045 14.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 AAG04356.1 - 0.00058 19.2 0.3 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 AAG04356.1 - 0.00058 19.3 0.5 0.085 12.2 0.0 2.5 1 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AAG04356.1 - 0.00088 19.0 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 AAG04356.1 - 0.0052 17.2 0.4 0.088 13.2 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 AAG04356.1 - 0.0063 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 AAG04356.1 - 0.0064 16.9 0.1 0.02 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 AAG04356.1 - 0.009 15.1 0.0 0.021 13.9 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 AAG04356.1 - 0.019 15.3 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 AAG04356.1 - 0.028 15.0 0.0 0.076 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAG04356.1 - 0.038 14.5 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Resolvase PF00239.21 AAG04356.1 - 0.044 13.9 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Resolvase, N terminal domain AAA_14 PF13173.6 AAG04356.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AAG04356.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 AAG04356.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 AAG04356.1 - 0.062 13.0 1.4 0.29 10.9 0.1 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 AAG04356.1 - 0.079 12.9 0.2 0.3 11.0 0.1 1.9 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.6 AAG04356.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAG04356.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAG04356.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 AAG04356.1 - 0.13 11.4 0.0 0.75 8.9 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 AAG04356.1 - 0.25 11.7 0.5 2.5 8.4 0.1 2.2 1 1 1 2 2 2 0 AAA domain 4HBT PF03061.22 AAG04357.1 - 1.8e-17 63.5 0.0 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAG04357.1 - 6.7e-09 36.3 0.0 8.1e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 AAG04357.1 - 0.00075 18.9 0.0 0.00087 18.7 0.0 1.0 1 0 0 1 1 1 1 Acyl-ACP thioesterase MotA_ExbB PF01618.16 AAG04358.1 - 3.9e-43 146.2 0.1 5.5e-43 145.7 0.1 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family LapA_dom PF06305.11 AAG04358.1 - 0.21 11.4 1.7 0.58 10.0 0.3 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ExbD PF02472.16 AAG04359.1 - 6.6e-30 103.9 0.5 7.7e-30 103.7 0.5 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_2 PF13103.6 AAG04360.1 - 6.7e-12 45.5 0.1 1.9e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 TonB C terminal TonB_C PF03544.14 AAG04360.1 - 4.6e-06 27.0 0.0 4.6e-06 27.0 0.0 3.3 2 2 1 3 3 3 1 Gram-negative bacterial TonB protein C-terminal Mitofilin PF09731.9 AAG04360.1 - 0.00078 18.4 48.7 0.001 18.0 48.7 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF3328 PF11807.8 AAG04360.1 - 0.16 11.7 2.9 0.25 11.1 2.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) TFIIA PF03153.13 AAG04360.1 - 1.3 8.9 34.8 1.9 8.4 34.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit THRAP3_BCLAF1 PF15440.6 AAG04360.1 - 1.4 7.9 30.0 1.9 7.4 30.0 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family GREB1 PF15782.5 AAG04360.1 - 1.8 5.6 22.5 1.9 5.5 22.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PD40 PF07676.12 AAG04361.1 - 9.2e-47 156.1 1.8 2e-13 49.9 0.1 6.2 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat TolB_N PF04052.13 AAG04361.1 - 2.1e-30 105.0 0.0 7.2e-30 103.3 0.0 1.8 2 0 0 2 2 2 1 TolB amino-terminal domain DPPIV_N PF00930.21 AAG04361.1 - 3.7e-07 29.2 0.0 0.027 13.3 0.0 3.1 1 1 3 4 4 4 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 AAG04361.1 - 5.5e-06 26.3 0.0 0.19 11.4 0.0 3.5 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Pectate_lyase22 PF14583.6 AAG04361.1 - 0.0085 14.8 0.0 1.8 7.1 0.0 2.8 1 1 1 3 3 3 1 Oligogalacturonate lyase Peptidase_S9_N PF02897.15 AAG04361.1 - 0.034 13.0 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 AAG04361.1 - 4.2 7.1 4.7 37 4.1 0.5 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature OmpA PF00691.20 AAG04362.1 - 2.3e-25 88.8 0.0 3.3e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 OmpA family TPR_6 PF13174.6 AAG04363.1 - 1.7e-17 62.8 7.0 9.8e-07 29.0 0.0 4.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AAG04363.1 - 1.9e-12 46.9 0.1 0.00013 22.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAG04363.1 - 3.2e-12 46.9 3.2 6.7e-09 36.3 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TolA_bind_tri PF16331.5 AAG04363.1 - 4.9e-12 45.8 9.1 5.4e-12 45.6 7.4 1.8 2 0 0 2 2 2 1 TolA binding protein trimerisation TPR_2 PF07719.17 AAG04363.1 - 3.8e-11 42.2 0.3 0.014 15.5 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat YfiO PF13525.6 AAG04363.1 - 2.1e-10 40.6 1.0 6.7e-10 39.0 1.0 1.8 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_19 PF14559.6 AAG04363.1 - 3.1e-09 37.2 7.0 2.5e-06 27.9 0.3 2.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAG04363.1 - 6.1e-06 26.4 0.8 0.00019 21.7 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 AAG04363.1 - 3.7e-05 23.6 0.2 0.37 11.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 AAG04363.1 - 0.00014 21.7 0.4 0.00014 21.7 0.4 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_18 PF13512.6 AAG04363.1 - 0.0018 18.4 3.1 0.035 14.2 0.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 AAG04363.1 - 0.0033 16.9 1.1 0.0052 16.2 0.0 1.7 2 0 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 AAG04363.1 - 0.012 15.4 1.6 12 5.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Cep57_MT_bd PF06657.13 AAG04363.1 - 0.014 15.8 1.5 0.03 14.8 1.5 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 TPR_17 PF13431.6 AAG04363.1 - 0.038 14.4 2.8 7.5 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat APG6_N PF17675.1 AAG04363.1 - 0.11 13.0 3.7 0.23 12.0 3.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 AAG04363.1 - 0.57 10.0 4.8 1.1 9.1 4.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Fis1_TPR_C PF14853.6 AAG04363.1 - 7.1 6.8 7.7 2.9 8.0 0.2 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Radical_SAM PF04055.21 AAG04364.1 - 2.6e-15 57.2 0.0 3.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAG04364.1 - 1.2e-10 41.6 0.0 1.9e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAG04364.1 - 7.8e-07 29.4 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain PyrI_C PF02748.15 AAG04364.1 - 0.096 12.6 0.2 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain QueC PF06508.13 AAG04365.1 - 2.3e-80 269.0 0.0 2.6e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AAG04365.1 - 2.2e-09 37.5 0.0 2.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 AAG04365.1 - 0.0051 16.0 0.1 0.0074 15.4 0.1 1.2 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 AAG04365.1 - 0.0071 15.2 0.1 0.01 14.7 0.1 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Arginosuc_synth PF00764.19 AAG04365.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 AAG04365.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) rve PF00665.26 AAG04367.1 - 2.4e-32 111.6 0.2 2.4e-32 111.6 0.2 1.5 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAG04367.1 - 7.2e-14 52.2 0.0 1.1e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 DDE domain HTH_21 PF13276.6 AAG04367.1 - 1.8e-13 50.4 0.2 4.2e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 HTH-like domain rve_3 PF13683.6 AAG04367.1 - 6.2e-11 41.9 1.1 3.5e-10 39.5 0.7 2.4 3 0 0 3 3 3 1 Integrase core domain rve_2 PF13333.6 AAG04367.1 - 0.039 14.1 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_1 PF01527.20 AAG04368.1 - 4.6e-21 74.9 0.9 6.2e-21 74.5 0.9 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAG04368.1 - 6.7e-05 22.6 0.5 0.00048 19.8 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 AAG04368.1 - 9.7e-05 22.3 0.2 0.0002 21.3 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 AAG04368.1 - 0.0014 18.7 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain VasL PF12486.8 AAG04368.1 - 0.0083 16.0 0.7 0.012 15.5 0.7 1.2 1 0 0 1 1 1 1 Type VI secretion system, EvfB, or VasL Shugoshin_N PF07558.11 AAG04368.1 - 0.0098 15.7 1.0 0.016 15.1 1.0 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 AAG04368.1 - 0.011 16.1 2.0 0.011 16.1 0.7 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 AAG04368.1 - 0.015 15.5 3.0 0.032 14.5 3.0 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 AAG04368.1 - 0.044 14.1 0.3 0.067 13.5 0.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 AAG04368.1 - 0.087 13.3 3.4 0.2 12.1 3.4 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 AAG04368.1 - 0.13 12.0 4.6 0.27 11.1 4.6 1.6 1 1 0 1 1 1 0 Septum formation initiator M PF02370.16 AAG04368.1 - 0.2 12.3 2.6 1.6 9.5 0.3 2.5 1 1 0 2 2 2 0 M protein repeat FpoO PF10621.9 AAG04370.1 - 0.075 13.4 0.1 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO Thioredoxin_4 PF13462.6 AAG04371.1 - 7.4e-18 65.3 0.0 1e-17 64.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AAG04371.1 - 3.2e-11 43.4 0.1 3.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AAG04371.1 - 4.5e-05 23.9 0.0 7.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AAG04371.1 - 0.0015 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 AAG04371.1 - 0.015 15.2 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin HTH_Tnp_1 PF01527.20 AAG04372.1 - 8e-17 61.3 0.4 1.1e-16 60.8 0.4 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAG04372.1 - 2.6e-06 27.4 0.5 4.7e-06 26.6 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG04372.1 - 3.2e-06 26.8 0.7 8.1e-06 25.5 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAG04372.1 - 8.2e-06 25.1 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 AAG04372.1 - 0.00025 20.6 0.0 0.0028 17.2 0.0 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 AAG04372.1 - 0.0011 19.0 0.0 0.0062 16.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Terminase_5 PF06056.12 AAG04372.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) LZ_Tnp_IS481 PF13011.6 AAG04372.1 - 0.002 18.6 0.0 0.0037 17.8 0.0 1.4 1 1 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_Tnp_1_2 PF13022.6 AAG04372.1 - 0.0039 17.3 0.0 0.0047 17.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_17 PF12728.7 AAG04372.1 - 0.0041 17.3 0.0 0.0091 16.2 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 AAG04372.1 - 0.011 15.5 0.3 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_psq PF05225.16 AAG04372.1 - 0.024 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain RepB PF07506.11 AAG04372.1 - 0.034 14.3 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 RepB plasmid partitioning protein HTH_29 PF13551.6 AAG04372.1 - 0.043 13.8 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.6 AAG04372.1 - 0.044 13.5 0.2 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain GRIM-19 PF06212.12 AAG04372.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 GRIM-19 protein UPF0122 PF04297.14 AAG04372.1 - 0.086 13.1 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_IS630 PF01710.16 AAG04372.1 - 0.087 12.9 0.1 0.1 12.7 0.1 1.2 1 1 0 1 1 1 0 Transposase HTH_22 PF13309.6 AAG04372.1 - 0.093 12.8 0.0 0.25 11.4 0.0 1.8 1 1 0 1 1 1 0 HTH domain AAA_27 PF13514.6 AAG04372.1 - 0.096 12.3 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.6 AAG04372.1 - 0.32 11.5 2.2 0.41 11.1 2.0 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Microcin PF03526.13 AAG04373.1 - 5.4e-28 96.6 0.1 5.4e-28 96.6 0.1 1.7 2 0 0 2 2 2 1 Colicin E1 (microcin) immunity protein Bestrophin PF01062.21 AAG04373.1 - 0.53 9.6 3.2 0.66 9.3 3.2 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Colicin PF01024.19 AAG04374.1 - 2e-88 295.1 6.0 2e-88 295.1 6.0 1.7 2 0 0 2 2 2 1 Colicin pore forming domain TF_AP-2 PF03299.14 AAG04374.1 - 0.0084 16.1 2.2 0.0084 16.1 2.2 2.2 3 0 0 3 3 3 1 Transcription factor AP-2 CdiI_2 PF18593.1 AAG04374.1 - 0.17 12.5 3.7 2.4 8.9 1.4 3.2 2 1 0 2 2 2 0 CdiI immunity protein HTH_Tnp_1 PF01527.20 AAG04375.1 - 1e-22 80.2 0.0 1.3e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAG04375.1 - 0.0001 22.3 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG04375.1 - 0.00095 18.9 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAG04375.1 - 0.0029 17.6 0.1 0.0052 16.8 0.0 1.7 2 1 0 2 2 2 1 Winged helix-turn helix Mga PF05043.13 AAG04375.1 - 0.14 12.8 0.0 12 6.6 0.0 2.1 2 0 0 2 2 2 0 Mga helix-turn-helix domain rve_3 PF13683.6 AAG04376.1 - 4.9e-31 106.3 0.8 1.7e-30 104.6 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 AAG04376.1 - 2.7e-26 92.1 0.0 5.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AAG04376.1 - 4.2e-12 46.0 10.1 9.6e-12 44.9 10.1 1.6 1 0 0 1 1 1 1 HTH-like domain HTH_32 PF13565.6 AAG04376.1 - 0.00026 21.6 2.2 0.00026 21.6 2.2 2.5 2 1 1 3 3 3 1 Homeodomain-like domain rve_2 PF13333.6 AAG04376.1 - 0.0047 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.18 AAG04376.1 - 0.0088 16.3 1.3 0.023 14.9 1.3 1.8 1 0 0 1 1 1 1 Transposase 4HBT PF03061.22 AAG04377.1 - 6.8e-18 64.8 0.0 8.8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAG04377.1 - 2.7e-06 27.9 0.0 3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily CMV_1a_C PF12503.8 AAG04378.1 - 0.0086 16.1 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 2 Cucumber mosaic virus 1a protein C terminal NUDIX PF00293.28 AAG04379.1 - 1.8e-19 70.0 0.0 2.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_N PF12535.8 AAG04379.1 - 1.3e-13 50.4 0.1 2.3e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Hydrolase of X-linked nucleoside diphosphate N terminal Hemolysin_N PF12563.8 AAG04379.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Hemolytic toxin N terminal DUF4871 PF16167.5 AAG04379.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) Hpt PF01627.23 AAG04380.1 - 2e-12 47.2 1.7 3.9e-12 46.3 1.7 1.6 1 1 0 1 1 1 1 Hpt domain Fimbrial PF00419.20 AAG04381.1 - 1.2e-11 45.1 4.2 1.8e-11 44.5 4.2 1.3 1 1 0 1 1 1 1 Fimbrial protein FimA PF16970.5 AAG04381.1 - 0.00042 20.5 3.8 0.00042 20.5 3.8 2.4 1 1 1 2 2 2 1 Type-1 fimbrial protein, A PapD_N PF00345.20 AAG04382.1 - 5.8e-41 139.3 0.1 9.9e-41 138.6 0.1 1.4 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAG04382.1 - 5.7e-18 65.0 0.3 2e-17 63.3 0.3 2.0 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain DNA_processg_A PF02481.15 AAG04382.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A Usher PF00577.20 AAG04383.1 - 2.5e-165 551.5 18.4 3e-165 551.2 18.4 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AAG04383.1 - 1.6e-41 141.7 0.0 3.9e-41 140.5 0.0 1.7 2 0 0 2 2 2 1 PapC N-terminal domain PapC_C PF13953.6 AAG04383.1 - 6.5e-16 57.9 0.0 2.5e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 PapC C-terminal domain Big_6 PF17936.1 AAG04383.1 - 0.04 14.2 0.1 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial Ig domain DNA_binding_1 PF01035.20 AAG04384.1 - 1.5e-31 108.4 0.0 2e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 AAG04384.1 - 1.3e-08 35.6 0.0 2.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain AMP-binding PF00501.28 AAG04385.1 - 1.5e-72 244.5 0.0 2e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG04385.1 - 8.1e-09 36.3 0.0 1.5e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACP_syn_III PF08545.10 AAG04386.1 - 0.0015 18.4 0.1 0.0023 17.7 0.1 1.3 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2017 PF09438.10 AAG04386.1 - 0.098 12.5 0.4 0.63 9.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2017) Peptidase_M22 PF00814.25 AAG04386.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycoprotease family ACP_syn_III_C PF08541.10 AAG04387.1 - 3e-21 75.4 0.0 7.9e-21 74.0 0.0 1.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAG04387.1 - 1.1e-18 66.8 0.7 2.1e-18 66.0 0.7 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.12 AAG04387.1 - 0.018 14.4 0.7 0.11 11.8 0.7 2.0 1 1 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Ketoacyl-synt_C PF02801.22 AAG04387.1 - 0.057 13.4 0.0 4.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III_C PF08541.10 AAG04388.1 - 2.4e-28 98.1 0.0 3.3e-27 94.5 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAG04388.1 - 2.8e-23 81.6 0.5 4.8e-23 80.8 0.5 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AAG04388.1 - 1.2e-05 24.9 0.0 0.0035 16.7 0.0 2.4 2 1 0 2 2 2 2 Thiolase, N-terminal domain Chal_sti_synt_N PF00195.19 AAG04388.1 - 0.0079 15.6 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain SpoVAD PF07451.11 AAG04388.1 - 0.0091 14.7 0.0 0.04 12.6 0.0 1.9 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) HMG_CoA_synt_C PF08540.10 AAG04388.1 - 0.25 10.9 0.0 2.7 7.5 0.0 1.9 1 1 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Lactamase_B PF00753.27 AAG04389.1 - 8.8e-27 94.4 0.1 1.1e-26 94.1 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG04389.1 - 2e-05 24.2 0.1 3.7e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Chorismate_bind PF00425.18 AAG04390.1 - 3.4e-82 275.9 0.0 4.3e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AAG04390.1 - 4.3e-06 27.0 0.0 1.1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region GATase PF00117.28 AAG04391.1 - 1.8e-44 151.8 0.0 2e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAG04391.1 - 5.3e-10 39.4 0.0 2.9e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 LysR_substrate PF03466.20 AAG04392.1 - 4.1e-14 52.4 0.0 6.7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04392.1 - 1.2e-10 41.2 0.0 2.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family NadA PF02445.16 AAG04393.1 - 2.1e-105 352.2 0.0 2.4e-105 352.0 0.0 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein Peptidase_M48 PF01435.18 AAG04394.1 - 3.3e-32 111.9 0.3 5.3e-32 111.2 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M48 TPR_19 PF14559.6 AAG04394.1 - 1e-14 54.8 10.5 6.6e-07 29.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAG04394.1 - 8.7e-06 26.1 18.0 0.018 15.8 0.0 5.5 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAG04394.1 - 0.00047 20.1 1.5 0.64 10.3 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAG04394.1 - 0.00058 20.1 4.5 4.6 7.9 0.4 5.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAG04394.1 - 0.0051 17.4 17.7 0.48 11.1 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAG04394.1 - 0.012 15.8 3.4 4.5 7.6 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAG04394.1 - 0.026 15.1 11.2 0.052 14.2 0.1 5.2 5 1 1 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AAG04394.1 - 0.066 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Peptidase_M43 PF05572.13 AAG04394.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF4157 PF13699.6 AAG04394.1 - 0.67 10.2 0.1 0.67 10.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4157) TusA PF01206.17 AAG04395.1 - 9.9e-22 76.6 0.0 1.1e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Sulfurtransferase TusA AI-2E_transport PF01594.16 AAG04396.1 - 3e-72 243.5 40.3 3.4e-72 243.4 40.3 1.0 1 0 0 1 1 1 1 AI-2E family transporter AhpC-TSA PF00578.21 AAG04397.1 - 3.1e-36 124.0 0.1 3.6e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG04397.1 - 2.5e-16 59.7 0.0 3.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AAG04397.1 - 0.0058 16.7 0.1 0.022 14.9 0.1 1.7 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 AAG04397.1 - 0.012 15.1 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) ACT_6 PF13740.6 AAG04398.1 - 1.5e-15 56.9 0.1 1.5e-14 53.7 0.0 2.1 2 1 0 2 2 2 1 ACT domain DHDPS PF00701.22 AAG04399.1 - 1.5e-109 365.2 0.0 1.7e-109 365.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Lipoprotein_18 PF06804.11 AAG04400.1 - 3.6e-22 78.8 0.0 4.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 NlpB/DapX lipoprotein DUF2076 PF09849.9 AAG04400.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Lactamase_B_2 PF12706.7 AAG04401.1 - 2.6e-23 82.6 0.7 3.3e-23 82.3 0.7 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAG04401.1 - 1e-17 64.8 0.1 1.3e-17 64.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 AAG04401.1 - 5.6e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 AAG04401.1 - 0.0019 17.6 0.1 0.0069 15.8 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain SAICAR_synt PF01259.18 AAG04402.1 - 5.6e-65 219.4 0.0 6.4e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Glycos_transf_2 PF00535.26 AAG04403.1 - 8.8e-25 87.5 0.0 1.3e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAG04403.1 - 1.5e-18 67.5 0.0 2.3e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAG04403.1 - 7e-07 29.0 0.0 2.6e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAG04403.1 - 0.00052 20.5 0.4 0.0012 19.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAG04403.1 - 0.00065 19.7 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 HTH_IclR PF09339.10 AAG04404.1 - 5e-13 48.6 0.1 1.5e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain IclR PF01614.18 AAG04404.1 - 1.4e-10 41.1 0.0 3.5e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Bacterial transcriptional regulator MarR_2 PF12802.7 AAG04404.1 - 2.4e-05 24.1 0.1 7.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_29 PF13551.6 AAG04404.1 - 0.002 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Rrf2 PF02082.20 AAG04404.1 - 0.0041 17.4 0.1 0.053 13.9 0.0 2.4 3 0 0 3 3 3 1 Transcriptional regulator HTH_AsnC-type PF13404.6 AAG04404.1 - 0.033 14.0 0.7 0.096 12.5 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_47 PF16221.5 AAG04404.1 - 0.035 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 winged helix-turn-helix HTH_27 PF13463.6 AAG04404.1 - 0.037 14.5 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.22 AAG04404.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 AAG04404.1 - 0.073 12.9 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_5 PF01022.20 AAG04404.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAG04404.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Thiolase_C PF02803.18 AAG04405.1 - 3.4e-10 39.6 0.3 4e-07 29.7 0.2 2.6 2 0 0 2 2 2 2 Thiolase, C-terminal domain Thiolase_N PF00108.23 AAG04405.1 - 0.00089 18.7 1.9 2.3 7.5 0.0 3.3 3 0 0 3 3 3 3 Thiolase, N-terminal domain Attacin_N PF03768.15 AAG04405.1 - 0.021 14.9 1.0 1.2 9.3 0.3 2.7 2 0 0 2 2 2 0 Attacin, N-terminal region ATP-grasp_5 PF13549.6 AAG04406.1 - 1.4e-61 207.8 0.0 2.5e-61 206.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AAG04406.1 - 7.4e-41 139.2 0.2 7.4e-41 139.2 0.2 2.4 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAG04406.1 - 1.6e-24 86.6 0.1 6.4e-24 84.7 0.1 2.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 AAG04406.1 - 3.2e-11 43.8 0.0 8.4e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain CPSase_L_D2 PF02786.17 AAG04406.1 - 0.0049 16.4 0.1 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF1995 PF09353.10 AAG04406.1 - 0.15 12.1 0.2 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1995) MaoC_dehydratas PF01575.19 AAG04407.1 - 2.3e-26 91.8 0.0 3.4e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAG04407.1 - 1.3e-10 41.5 0.0 6.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MFS_1 PF07690.16 AAG04408.1 - 7.1e-53 179.8 66.6 1.6e-42 145.7 43.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG04408.1 - 2.7e-28 99.0 35.0 7.3e-27 94.3 35.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 AAG04408.1 - 7.2e-06 25.1 12.1 7.2e-06 25.1 12.1 2.6 2 1 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 AAG04408.1 - 1.4e-05 24.6 9.5 1.4e-05 24.6 9.5 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AAG04408.1 - 5.6e-05 21.6 10.1 0.0052 15.1 0.5 3.3 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Acyl-CoA_dh_1 PF00441.24 AAG04409.1 - 9.9e-28 97.2 6.6 1.9e-27 96.3 6.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 AAG04409.1 - 4.5e-08 33.4 5.7 4.5e-08 33.4 5.7 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG04409.1 - 9.1e-08 32.8 0.2 2.9e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain ECH_1 PF00378.20 AAG04410.1 - 2.4e-50 171.2 0.0 2.6e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG04410.1 - 1.3e-22 80.7 0.8 8.8e-22 78.0 0.4 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Acyl-CoA_dh_M PF02770.19 AAG04411.1 - 1.7e-21 76.2 0.0 2.6e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG04411.1 - 4.9e-20 72.3 0.0 1.4e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAG04411.1 - 1.7e-17 64.0 0.0 3.1e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short_C2 PF13561.6 AAG04412.1 - 3.3e-42 144.6 0.8 5.4e-42 144.0 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG04412.1 - 4.9e-40 137.1 0.9 8.7e-40 136.3 0.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG04412.1 - 2e-19 70.2 0.7 3.7e-19 69.3 0.7 1.4 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 AAG04412.1 - 0.087 12.9 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MccV PF17508.2 AAG04412.1 - 0.4 11.3 5.2 0.13 12.8 2.0 1.8 2 0 0 2 2 2 0 Microcin V bacteriocin Ldh_1_N PF00056.23 AAG04412.1 - 0.56 10.3 2.3 2.7 8.1 2.3 2.1 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NMO PF03060.15 AAG04413.1 - 3.6e-54 184.4 3.7 4.8e-53 180.7 3.7 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 AAG04413.1 - 4e-12 45.8 0.1 2.6e-05 23.4 0.1 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AAG04413.1 - 2.8e-07 29.9 3.1 2.4e-06 26.8 1.7 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 AAG04413.1 - 3.1e-05 23.3 0.6 7.3e-05 22.1 0.6 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase OprD PF03573.13 AAG04414.1 - 3.4e-157 523.5 1.7 3.9e-157 523.3 1.7 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Porin_4 PF13609.6 AAG04414.1 - 0.0042 16.9 1.2 0.0082 15.9 1.2 1.5 1 0 0 1 1 1 1 Gram-negative porin GreA_GreB PF01272.19 AAG04415.1 - 9.2e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 1 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term VirE_N PF08800.10 AAG04415.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.6 1 1 1 2 2 2 0 VirE N-terminal domain Aldedh PF00171.22 AAG04416.1 - 9e-127 423.4 0.0 1.1e-126 423.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.24 AAG04417.1 - 1.5e-50 172.8 8.7 1.7e-50 172.6 8.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAG04417.1 - 2e-06 27.3 1.8 0.0001 21.7 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 AAG04417.1 - 0.00026 20.2 10.0 0.0016 17.6 10.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAG04417.1 - 0.00029 20.2 0.1 0.08 12.2 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG04417.1 - 0.00043 19.1 0.1 0.0013 17.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 AAG04417.1 - 0.00098 18.4 0.4 0.002 17.4 0.4 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 AAG04417.1 - 0.0011 19.2 2.6 0.0027 17.9 0.6 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 AAG04417.1 - 0.0016 17.8 0.4 0.013 14.9 0.3 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 AAG04417.1 - 0.0018 17.6 0.2 0.0028 16.9 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG04417.1 - 0.0023 17.3 1.2 0.0033 16.8 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAG04417.1 - 0.012 14.9 0.2 0.02 14.2 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AAG04417.1 - 0.048 12.7 0.8 0.073 12.1 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AAG04417.1 - 0.059 13.4 2.0 0.13 12.2 0.3 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 AAG04417.1 - 0.11 13.0 0.2 0.27 11.8 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAG04417.1 - 0.15 11.1 0.4 0.24 10.4 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2384 PF09722.10 AAG04418.1 - 1.6e-14 53.6 0.1 2.5e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) Phage_CII PF05269.11 AAG04418.1 - 0.0013 18.9 0.1 0.0016 18.6 0.1 1.5 1 1 0 1 1 1 1 Bacteriophage CII protein HTH_3 PF01381.22 AAG04418.1 - 0.0095 16.0 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix DUF1323 PF07037.11 AAG04418.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 Putative transcription regulator (DUF1323) P22_Cro PF14549.6 AAG04418.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_19 PF12844.7 AAG04418.1 - 0.16 12.0 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RES PF08808.11 AAG04419.1 - 2.7e-25 89.1 1.0 3.9e-25 88.6 1.0 1.2 1 0 0 1 1 1 1 RES domain RmuC PF02646.16 AAG04420.1 - 2.8e-107 358.2 4.3 2.8e-107 358.2 4.3 2.5 2 1 1 3 3 3 1 RmuC family Matrilin_ccoil PF10393.9 AAG04420.1 - 0.017 15.0 3.0 1.3 9.0 0.1 3.3 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF5344 PF17279.2 AAG04420.1 - 0.06 13.9 3.1 17 6.1 0.0 4.4 4 1 1 5 5 5 0 Family of unknown function (DUF5344) PE PF00934.20 AAG04420.1 - 0.19 12.0 3.7 1.6 9.1 0.1 3.5 3 0 0 3 3 3 0 PE family Atg14 PF10186.9 AAG04420.1 - 1.5 7.9 23.0 1.8 7.6 0.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 AAG04420.1 - 3.3 6.5 8.4 2 7.2 6.4 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein Penicil_amidase PF01804.18 AAG04421.1 - 1.1e-197 659.2 7.6 1.2e-197 659.0 7.6 1.0 1 0 0 1 1 1 1 Penicillin amidase GST_C_2 PF13410.6 AAG04421.1 - 0.11 12.5 0.7 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAG04422.1 - 9.8e-14 51.5 0.0 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAG04422.1 - 1.3e-11 44.8 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG04422.1 - 4.5e-11 42.8 0.0 7.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AAG04422.1 - 1.9e-10 40.9 0.0 5e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAG04422.1 - 4.6e-07 29.8 1.1 1.8e-06 27.9 1.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG04422.1 - 5.1e-07 29.8 0.0 8.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Helicase_C_3 PF13625.6 AAG04422.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SEC-C PF02810.15 AAG04423.1 - 1.4e-11 44.0 5.8 2.9e-11 43.1 5.8 1.6 1 0 0 1 1 1 1 SEC-C motif Zip PF02535.22 AAG04423.1 - 1.5 7.9 3.7 1.3 8.1 3.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 AAG04423.1 - 2.2 7.6 11.9 2.1 7.7 11.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LEA_2 PF03168.13 AAG04424.1 - 7.3e-22 77.8 0.0 9.6e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Late embryogenesis abundant protein Ribosomal_L12 PF00542.19 AAG04425.1 - 0.19 12.1 1.0 0.82 10.1 0.1 2.4 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain UPF0126 PF03458.13 AAG04426.1 - 7.3e-44 147.6 17.3 2.3e-22 78.6 3.2 2.1 2 0 0 2 2 2 2 UPF0126 domain ICMT PF04140.14 AAG04426.1 - 0.067 13.6 0.2 0.2 12.1 0.2 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family UPF0225 PF17775.1 AAG04428.1 - 5.8e-25 88.0 0.0 6.8e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 AAG04428.1 - 1.3e-11 44.2 25.2 4.5e-07 29.7 11.5 2.3 2 0 0 2 2 2 2 SEC-C motif Glyco_trans_4_4 PF13579.6 AAG04429.1 - 0.13 12.6 3.4 0.3 11.5 3.3 1.6 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain OmpA PF00691.20 AAG04430.1 - 4.7e-24 84.6 0.3 6.2e-24 84.2 0.3 1.1 1 0 0 1 1 1 1 OmpA family Gly-zipper_Omp PF13488.6 AAG04430.1 - 0.011 15.8 16.1 0.021 14.8 16.1 1.5 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 AAG04430.1 - 0.013 15.3 14.3 0.025 14.3 14.3 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Pilus_CpaD PF09476.10 AAG04430.1 - 0.019 14.7 0.1 0.033 13.9 0.0 1.4 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Gly-zipper_OmpA PF13436.6 AAG04430.1 - 0.051 13.4 13.0 0.11 12.2 13.0 1.5 1 0 0 1 1 1 0 Glycine-zipper domain Rick_17kDa_Anti PF05433.15 AAG04430.1 - 1.3 8.9 16.1 2.6 8.0 16.1 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1145 PF06611.12 AAG04431.1 - 5.1e-19 68.0 8.6 5.1e-19 68.0 8.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1145) CopD PF05425.13 AAG04433.1 - 3.5e-19 69.1 9.0 3.5e-19 69.1 9.0 2.0 1 1 1 2 2 2 1 Copper resistance protein D DUF2269 PF10027.9 AAG04433.1 - 5.3e-06 26.5 13.7 6.7e-06 26.2 13.7 1.1 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) UPF0093 PF03653.13 AAG04433.1 - 2.2 8.5 8.4 4.4 7.5 8.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0093) Tetraspanin PF00335.20 AAG04433.1 - 3.4 7.3 14.8 0.034 13.9 7.2 1.5 2 0 0 2 2 2 0 Tetraspanin family Helicase_C_2 PF13307.6 AAG04434.1 - 1.2e-34 119.9 0.0 2.2e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 AAG04434.1 - 4.5e-06 26.5 0.0 4.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AAG04434.1 - 0.0001 22.4 0.0 0.0027 17.7 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 AAG04434.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 DEAD_2 Helicase_C PF00271.31 AAG04434.1 - 0.047 14.0 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain AAA_30 PF13604.6 AAG04434.1 - 0.14 11.9 1.0 0.28 10.9 1.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAG04434.1 - 0.17 11.3 0.2 0.35 10.3 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein Glyco_hydro_42 PF02449.15 AAG04435.1 - 0.0049 16.2 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Beta-lactamase PF00144.24 AAG04436.1 - 3.1e-79 266.6 4.4 3.9e-79 266.3 4.4 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 AAG04436.1 - 0.053 13.1 0.1 0.91 9.1 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase enzyme family OmpA PF00691.20 AAG04437.1 - 5.5e-14 52.3 0.0 1.5e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 OmpA family Putative_PNPOx PF01243.20 AAG04438.1 - 1.5e-29 102.0 0.0 2.2e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 AAG04438.1 - 2.5e-19 69.1 5.5 6e-19 67.8 5.5 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 AAG04438.1 - 1.4e-08 35.2 0.0 2.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Diacid_rec PF05651.13 AAG04439.1 - 1.5e-49 167.1 0.0 2e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Putative sugar diacid recognition HTH_30 PF13556.6 AAG04439.1 - 1.2e-17 63.4 4.1 1.4e-17 63.2 2.2 2.1 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 AAG04439.1 - 2.4e-08 34.2 8.5 4.5e-08 33.4 3.2 2.8 1 1 1 2 2 2 2 GGDEF-like domain HTH_8 PF02954.19 AAG04439.1 - 2.3e-05 24.1 0.0 6.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family GntP_permease PF02447.16 AAG04440.1 - 3.2e-96 322.7 39.5 3.6e-96 322.6 39.5 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 AAG04440.1 - 8.2e-13 48.2 42.9 1.5e-07 30.9 22.3 2.1 1 1 0 2 2 2 2 Citrate transporter CHD5 PF04420.14 AAG04440.1 - 0.068 13.0 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 CHD5-like protein Gly_kinase PF02595.15 AAG04441.1 - 6.9e-149 495.8 6.2 7.7e-149 495.6 6.2 1.0 1 0 0 1 1 1 1 Glycerate kinase family Rick_17kDa_Anti PF05433.15 AAG04442.1 - 1.5e-07 31.2 27.7 2.5e-07 30.4 27.7 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AAG04442.1 - 3.6e-05 23.4 21.8 7.6e-05 22.4 21.8 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAG04442.1 - 0.00038 20.4 27.7 0.00067 19.6 27.7 1.4 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 AAG04442.1 - 0.033 13.9 4.3 0.041 13.6 4.3 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein MLTD_N PF06474.12 AAG04442.1 - 0.29 11.3 1.9 0.66 10.2 1.9 1.6 1 0 0 1 1 1 0 MltD lipid attachment motif DUF3482 PF11981.8 AAG04442.1 - 1 8.7 7.5 1.4 8.3 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Bacteriocin_IIc PF10439.9 AAG04442.1 - 3.2 7.9 19.6 0.62 10.2 16.1 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Proton_antipo_M PF00361.20 AAG04443.1 - 2.1e-64 217.6 24.3 2.1e-64 217.6 24.3 2.8 3 1 0 3 3 3 1 Proton-conducting membrane transporter MnhB PF04039.13 AAG04443.1 - 2.9e-37 127.7 13.0 2.9e-37 127.7 13.0 8.5 3 2 6 10 10 10 1 Domain related to MnhB subunit of Na+/H+ antiporter DUF4040 PF13244.6 AAG04443.1 - 1.3e-17 63.7 13.9 1.3e-17 63.7 13.9 5.5 6 0 0 6 6 6 1 Domain of unknown function (DUF4040) Proton_antipo_N PF00662.20 AAG04443.1 - 2.4e-11 43.5 0.1 2.4e-11 43.5 0.1 4.2 5 0 0 5 5 5 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Saf_2TM PF18303.1 AAG04443.1 - 0.078 12.6 0.7 0.66 9.5 0.7 2.7 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF3789 PF12664.7 AAG04443.1 - 0.29 10.9 5.0 2.1 8.2 5.0 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Oxidored_q2 PF00420.24 AAG04444.1 - 7.5e-26 89.8 0.9 8.6e-26 89.6 0.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Tail_VII PF17091.5 AAG04444.1 - 0.51 10.3 2.8 0.64 9.9 0.6 2.1 2 0 0 2 2 2 0 Inovirus G7P protein Proton_antipo_M PF00361.20 AAG04445.1 - 4.3e-41 141.0 20.4 9.6e-41 139.9 20.4 1.6 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAG04445.1 - 0.067 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus MNHE PF01899.16 AAG04446.1 - 2.1e-43 147.6 2.5 2.4e-43 147.4 2.5 1.0 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit MrpF_PhaF PF04066.13 AAG04447.1 - 1.2e-21 76.8 6.3 1.2e-21 76.8 6.3 2.0 2 0 0 2 2 2 2 Multiple resistance and pH regulation protein F (MrpF / PhaF) PhaG_MnhG_YufB PF03334.14 AAG04448.1 - 2.4e-27 95.0 7.1 2.8e-27 94.7 7.1 1.1 1 0 0 1 1 1 1 Na+/H+ antiporter subunit Gram_pos_anchor PF00746.21 AAG04448.1 - 2.3 8.2 6.4 19 5.3 3.3 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif EamA PF00892.20 AAG04449.1 - 1.8e-52 177.2 36.1 1.6e-26 93.1 12.8 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AAG04449.1 - 4.1e-07 29.6 3.1 0.0025 17.2 0.8 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 AAG04449.1 - 0.052 12.7 0.1 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Nucleotide-sugar transporter PALP PF00291.25 AAG04450.1 - 4.2e-43 147.8 0.0 5.4e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF374 PF04028.13 AAG04450.1 - 0.13 11.8 0.4 0.25 10.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Acetyltransf_1 PF00583.25 AAG04451.1 - 1.6e-17 63.8 0.0 2.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG04451.1 - 1e-09 38.4 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAG04451.1 - 6.6e-08 33.3 0.0 8.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG04451.1 - 1.5e-07 31.7 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG04451.1 - 6.3e-06 25.9 0.2 9.2e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG04451.1 - 0.00046 20.1 0.0 0.00097 19.1 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 AAG04451.1 - 0.00089 19.3 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAG04451.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAG04451.1 - 0.006 16.8 2.5 0.17 12.1 2.5 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF488 PF04343.13 AAG04454.1 - 8.7e-30 103.8 0.2 1.1e-29 103.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF488 adh_short_C2 PF13561.6 AAG04455.1 - 3.8e-13 49.5 0.0 4.7e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG04455.1 - 1.1e-06 28.2 0.1 7.9e-06 25.5 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 AAG04455.1 - 0.0019 17.3 0.0 0.0067 15.6 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 AAG04455.1 - 0.057 12.7 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 AAG04455.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 KR domain LysR_substrate PF03466.20 AAG04456.1 - 2.9e-39 134.6 6.3 2.9e-39 134.6 6.3 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04456.1 - 2.1e-18 66.0 1.2 2.1e-18 66.0 1.2 2.4 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG04456.1 - 0.016 15.0 0.2 0.044 13.6 0.2 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAG04456.1 - 0.094 12.1 0.5 0.59 9.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HATPase_c_3 PF13589.6 AAG04457.1 - 7.6e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.18 AAG04457.1 - 2.8e-08 33.1 0.0 6.4e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 AAG04457.1 - 0.00021 21.8 0.0 0.00043 20.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ImpA_N PF06812.12 AAG04457.1 - 0.1 12.7 0.1 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system Dpy-30 PF05186.13 AAG04457.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Dpy-30 motif TPR_20 PF14561.6 AAG04458.1 - 0.00026 21.3 1.9 0.00026 21.3 1.9 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat VWA_3 PF13768.6 AAG04458.1 - 0.1 12.5 2.2 2 8.4 0.7 2.8 3 0 0 3 3 3 0 von Willebrand factor type A domain TPR_19 PF14559.6 AAG04458.1 - 0.11 13.0 0.2 0.11 13.0 0.2 6.4 6 2 2 8 8 8 0 Tetratricopeptide repeat ABC_tran PF00005.27 AAG04459.1 - 2.4e-34 118.8 0.0 3.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG04459.1 - 7.5e-12 45.7 2.7 1.5e-06 28.3 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAG04459.1 - 0.00011 22.2 0.1 0.00054 19.9 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AAG04459.1 - 0.00014 21.5 0.1 0.0003 20.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAG04459.1 - 0.0029 17.4 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain BCA_ABC_TP_C PF12399.8 AAG04459.1 - 0.0032 17.3 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 AAG04459.1 - 0.0034 16.8 0.2 0.7 9.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAG04459.1 - 0.0059 16.2 0.0 0.02 14.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AAG04459.1 - 0.0074 15.1 0.2 3.1 6.5 0.2 2.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 AAG04459.1 - 0.0087 16.6 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG04459.1 - 0.011 16.1 0.5 0.023 15.1 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAG04459.1 - 0.011 15.8 0.1 0.036 14.1 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AAG04459.1 - 0.021 15.0 0.3 0.079 13.1 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAG04459.1 - 0.031 13.0 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG04459.1 - 0.043 14.1 0.5 0.25 11.6 0.5 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG04459.1 - 0.053 13.8 0.1 0.4 10.9 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 AAG04459.1 - 0.085 12.9 0.0 1.9 8.6 0.0 2.0 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 AAG04459.1 - 0.093 12.4 0.1 0.27 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAG04459.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 AAG04459.1 - 0.17 11.6 0.2 1.7 8.4 0.0 2.3 2 1 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 AAG04460.1 - 3.3e-34 118.3 0.0 5.8e-34 117.5 0.0 1.4 2 0 0 2 2 2 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAG04460.1 - 1.1e-10 41.1 0.1 2e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAG04460.1 - 4.7e-06 26.6 0.3 0.0024 17.8 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAG04460.1 - 0.00016 22.2 0.0 0.00019 22.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAG04460.1 - 0.0033 16.9 0.3 0.25 10.7 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 AAG04460.1 - 0.0063 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 AAG04460.1 - 0.012 15.8 0.5 0.26 11.5 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAG04460.1 - 0.013 15.2 0.1 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 AAG04460.1 - 0.019 14.7 0.1 0.073 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 AAG04460.1 - 0.028 14.0 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_15 PF13175.6 AAG04460.1 - 0.029 14.1 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 AAG04460.1 - 0.034 14.3 0.1 0.053 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAG04460.1 - 0.037 13.6 0.3 3 7.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAG04460.1 - 0.048 14.0 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AAG04460.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 AAG04460.1 - 0.097 12.3 0.4 0.23 11.0 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain BPD_transp_2 PF02653.16 AAG04461.1 - 1.2e-51 175.5 36.5 1.2e-51 175.5 36.5 2.3 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3382 PF11862.8 AAG04461.1 - 6.6e-20 71.2 7.1 6.6e-20 71.2 7.1 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3382) BPD_transp_2 PF02653.16 AAG04462.1 - 2.3e-54 184.3 40.6 2.8e-54 184.1 40.6 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF3413 PF11893.8 AAG04462.1 - 0.0044 16.2 0.5 0.0044 16.2 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3413) Peripla_BP_6 PF13458.6 AAG04463.1 - 3.5e-67 227.5 6.4 4.2e-67 227.2 6.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAG04463.1 - 7.8e-33 114.0 0.0 9.3e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAG04463.1 - 5.3e-28 98.1 0.0 6.3e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Fe-ADH PF00465.19 AAG04463.1 - 0.033 13.0 0.0 0.089 11.6 0.0 1.7 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase ZnuA PF01297.17 AAG04463.1 - 0.058 12.8 0.0 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic LppC PF04348.13 AAG04463.1 - 0.11 11.3 0.3 0.24 10.2 0.2 1.5 2 0 0 2 2 2 0 LppC putative lipoprotein DUF4179 PF13786.6 AAG04463.1 - 0.38 11.3 0.0 0.38 11.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) DUF2288 PF10052.9 AAG04464.1 - 3.7e-31 107.0 0.1 4.2e-31 106.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2288) DUF5064 PF16703.5 AAG04465.1 - 2.1e-52 176.5 0.3 2.4e-52 176.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5064) Flg_bb_rod PF00460.20 AAG04466.1 - 3.8e-09 36.3 0.3 9e-09 35.1 0.3 1.7 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAG04467.1 - 2e-14 53.5 7.5 5e-14 52.2 7.5 2.0 1 1 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAG04467.1 - 5.5e-10 39.0 3.1 1.7e-09 37.4 3.1 1.8 1 0 0 1 1 1 1 Flagella basal body rod protein FlgD PF03963.14 AAG04468.1 - 3.8e-25 88.0 1.2 7.1e-25 87.1 1.2 1.4 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region FlgD_ig PF13860.6 AAG04468.1 - 1.2e-22 79.5 0.5 4.1e-22 77.8 0.3 2.0 1 1 1 2 2 2 1 FlgD Ig-like domain FLgD_tudor PF13861.6 AAG04468.1 - 1.3e-17 63.8 1.9 1.3e-17 63.8 1.9 2.3 3 1 0 3 3 3 1 FlgD Tudor-like domain CHU_C PF13585.6 AAG04468.1 - 0.022 14.8 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family DUF2271 PF10029.9 AAG04468.1 - 0.089 12.4 0.7 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) VWA_N PF08399.11 AAG04468.1 - 0.098 13.1 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 VWA N-terminal FlaE PF07559.14 AAG04469.1 - 2.6e-27 95.8 2.2 2.6e-27 95.8 2.2 2.2 2 0 0 2 2 2 1 Flagellar basal body protein FlaE Flg_bbr_C PF06429.13 AAG04469.1 - 3.3e-19 68.8 2.5 9e-19 67.4 0.1 2.7 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAG04469.1 - 9.2e-08 31.9 2.5 2.9e-07 30.3 2.5 2.0 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAG04470.1 - 1.9e-18 66.4 0.4 4.5e-18 65.1 0.2 1.8 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAG04470.1 - 2.1e-06 27.5 1.5 5.5e-06 26.2 1.5 1.8 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAG04471.1 - 1.3e-26 92.5 2.2 4.2e-26 90.9 2.2 1.9 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAG04471.1 - 6.2e-11 42.0 1.7 1e-10 41.3 0.2 2.3 2 0 0 2 2 2 1 Flagella basal body rod protein FlgH PF02107.16 AAG04472.1 - 3.2e-61 205.8 0.2 3.7e-61 205.6 0.2 1.0 1 0 0 1 1 1 1 Flagellar L-ring protein FlgI PF02119.16 AAG04473.1 - 4.4e-146 486.2 3.5 5e-146 486.0 3.5 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein SepF PF04472.12 AAG04473.1 - 0.072 13.4 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 Cell division protein SepF gerPA PF10676.9 AAG04473.1 - 0.13 12.6 4.7 0.58 10.4 0.8 2.7 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF Glucosaminidase PF01832.20 AAG04474.1 - 8.4e-23 80.7 0.4 2.5e-22 79.1 0.3 1.8 2 0 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Rod-binding PF10135.9 AAG04474.1 - 4.1e-17 62.5 1.9 1.9e-16 60.3 1.9 2.3 1 0 0 1 1 1 1 Rod binding protein SLT_2 PF13406.6 AAG04474.1 - 0.0034 16.6 0.4 0.072 12.3 0.0 2.3 2 0 0 2 2 2 1 Transglycosylase SLT domain Bud13 PF09736.9 AAG04474.1 - 0.059 13.8 0.4 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Flg_bbr_C PF06429.13 AAG04475.1 - 2.3e-10 40.5 2.4 4e-10 39.7 0.4 2.6 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Baculo_PEP_C PF04513.12 AAG04475.1 - 0.00091 19.3 8.8 0.00091 19.3 8.8 2.5 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 AAG04475.1 - 0.0078 14.9 1.0 0.012 14.3 1.0 1.2 1 0 0 1 1 1 1 AAA domain MbeD_MobD PF04899.12 AAG04475.1 - 0.016 15.3 1.4 0.054 13.6 0.4 2.4 1 1 1 2 2 2 0 MbeD/MobD like DUF4693 PF15764.5 AAG04475.1 - 0.035 13.7 0.3 0.066 12.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) LXG PF04740.12 AAG04475.1 - 0.074 12.8 4.5 0.31 10.7 0.0 2.6 2 1 1 3 3 3 0 LXG domain of WXG superfamily F_actin_bind PF08919.10 AAG04475.1 - 0.088 12.9 1.9 0.2 11.8 0.6 2.3 2 0 0 2 2 2 0 F-actin binding Prominin PF05478.11 AAG04475.1 - 0.1 10.5 2.8 0.16 9.9 2.8 1.2 1 0 0 1 1 1 0 Prominin CCDC144C PF14915.6 AAG04475.1 - 0.19 10.8 2.3 0.28 10.3 2.3 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Fib_alpha PF08702.10 AAG04475.1 - 0.35 11.0 1.5 0.68 10.1 0.5 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 AAG04475.1 - 3.5 8.0 4.8 1.1 9.7 1.2 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 AAG04475.1 - 6.4 6.0 11.8 0.8 9.0 4.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Flagellin_N PF00669.20 AAG04476.1 - 7.4e-21 74.7 7.1 7.4e-21 74.7 7.1 2.3 3 1 0 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AAG04476.1 - 2e-06 28.0 1.5 2e-06 28.0 1.5 2.2 2 1 0 2 2 2 1 Bacterial flagellin C-terminal helical region Methyltransf_31 PF13847.6 AAG04477.1 - 1.1e-18 67.5 0.0 1.6e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG04477.1 - 6.7e-15 55.6 0.0 1.5e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG04477.1 - 5.1e-14 52.8 0.0 8.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG04477.1 - 1.6e-12 47.6 0.0 2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG04477.1 - 2.9e-08 34.2 0.0 8.2e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 AAG04477.1 - 1.7e-07 30.9 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 AAG04477.1 - 5.1e-05 22.9 0.0 0.00013 21.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_20 PF12147.8 AAG04477.1 - 0.00013 21.3 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 AAG04477.1 - 0.00019 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 AAG04477.1 - 0.0024 17.9 0.0 0.005 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAG04477.1 - 0.0035 16.7 0.0 0.0068 15.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 AAG04477.1 - 0.0045 16.5 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.11 AAG04477.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 AAG04477.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 AAG04477.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 AAG04477.1 - 0.031 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) TehB PF03848.14 AAG04477.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB HAD PF12710.7 AAG04478.1 - 1.9e-16 61.0 0.0 2.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG04478.1 - 5.3e-08 33.4 0.0 0.00034 21.0 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAG04478.1 - 1e-05 25.4 0.1 0.00047 20.0 0.0 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase NTP_transf_3 PF12804.7 AAG04479.1 - 8.5e-15 55.5 0.1 1.1e-14 55.1 0.1 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAG04479.1 - 9.3e-08 32.1 0.0 1.9e-07 31.0 0.0 1.5 1 1 1 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyphos_transf PF04464.14 AAG04480.1 - 3.4e-13 49.3 0.0 5.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Glycos_transf_2 PF00535.26 AAG04480.1 - 2.5e-08 33.9 0.0 9.9e-06 25.5 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAG04480.1 - 0.00057 19.8 0.0 0.0029 17.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 AAG04480.1 - 0.0023 17.4 0.0 0.0068 15.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Flagellin_N PF00669.20 AAG04481.1 - 7.3e-41 139.5 19.7 7.3e-41 139.5 19.7 4.3 2 1 3 5 5 5 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AAG04481.1 - 2.8e-26 91.7 7.0 2.8e-26 91.7 7.0 3.5 4 0 0 4 4 4 1 Bacterial flagellin C-terminal helical region Flagellin_IN PF07196.13 AAG04481.1 - 2.6e-09 37.1 19.7 5.2e-09 36.2 9.6 5.1 5 0 0 5 5 5 2 Flagellin hook IN motif Halo_GVPC PF05465.13 AAG04481.1 - 0.085 13.1 3.6 0.31 11.3 0.2 2.6 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat FlaG PF03646.15 AAG04482.1 - 3.3e-23 81.8 0.0 3.8e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 FlaG protein FlgD_ig PF13860.6 AAG04482.1 - 0.095 12.6 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 FlgD Ig-like domain FliD_C PF07195.12 AAG04483.1 - 2.5e-60 203.9 10.1 2.5e-60 203.9 10.1 2.4 3 1 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus FliD_N PF02465.18 AAG04483.1 - 1.1e-16 61.3 11.8 1.1e-16 61.3 11.8 3.7 4 0 0 4 4 4 1 Flagellar hook-associated protein 2 N-terminus Flagellin_IN PF07196.13 AAG04483.1 - 3.8e-09 36.6 6.0 3.8e-09 36.6 6.0 3.3 3 0 0 3 3 3 1 Flagellin hook IN motif MscS_porin PF12795.7 AAG04483.1 - 0.021 14.4 2.0 0.021 14.4 2.0 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 AAG04483.1 - 0.027 14.7 1.5 0.027 14.7 1.5 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 AAG04483.1 - 0.034 14.3 3.7 0.04 14.1 1.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 AAG04483.1 - 0.046 13.7 0.4 0.046 13.7 0.4 2.4 3 0 0 3 3 3 0 Prefoldin subunit Syntaxin-6_N PF09177.11 AAG04483.1 - 0.048 14.2 2.0 0.71 10.5 0.2 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.12 AAG04483.1 - 0.16 12.6 1.9 0.29 11.8 0.7 2.1 2 0 0 2 2 2 0 SlyX DUF1664 PF07889.12 AAG04483.1 - 0.16 12.0 6.5 0.041 13.9 1.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FliS PF02561.14 AAG04484.1 - 2.5e-36 124.4 0.0 2.8e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Flagellar protein FliS FliT PF05400.13 AAG04485.1 - 1.6e-08 35.2 3.4 2.5e-08 34.6 3.4 1.3 1 0 0 1 1 1 1 Flagellar protein FliT Sigma54_activat PF00158.26 AAG04486.1 - 2.6e-76 255.0 0.0 4.1e-76 254.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain FleQ PF06490.11 AAG04486.1 - 1.7e-30 105.6 0.1 5.4e-30 104.0 0.0 1.9 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ Sigma54_activ_2 PF14532.6 AAG04486.1 - 9.7e-23 80.8 0.0 3.4e-22 79.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG04486.1 - 6.4e-13 48.3 1.3 1.8e-12 46.8 1.3 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAG04486.1 - 2e-07 31.1 0.0 5.7e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAG04486.1 - 2.8e-06 27.8 0.3 3.7e-05 24.2 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain HTH_50 PF18024.1 AAG04486.1 - 2.2e-05 24.0 0.2 7.5e-05 22.3 0.2 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain AAA_7 PF12775.7 AAG04486.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 AAG04486.1 - 0.0074 16.7 0.0 0.058 13.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAG04486.1 - 0.009 15.4 0.1 2.8 7.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAG04486.1 - 0.021 15.1 0.0 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 AAG04486.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_30 PF13556.6 AAG04486.1 - 0.11 12.4 0.2 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RPA_interact_N PF14766.6 AAG04486.1 - 0.63 9.7 3.0 3 7.5 1.4 2.6 2 0 0 2 2 2 0 Replication protein A interacting N-terminal HATPase_c PF02518.26 AAG04487.1 - 2.8e-22 79.3 0.0 5.1e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG04487.1 - 1.3e-11 44.4 0.5 1.3e-11 44.4 0.5 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAG04487.1 - 1.2e-07 31.6 0.0 3.7e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAG04487.1 - 2.2e-05 24.7 0.3 0.00011 22.5 0.0 2.3 2 1 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AAG04487.1 - 4.9e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAG04487.1 - 7.2e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAG04487.1 - 0.00036 20.5 0.0 0.00082 19.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AAG04487.1 - 0.0021 18.0 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HalX PF08663.10 AAG04487.1 - 0.4 11.0 7.0 14 6.0 1.0 3.8 4 1 0 4 4 3 0 HalX domain Interferon PF00143.19 AAG04487.1 - 0.83 9.8 3.4 1.2 9.3 0.7 2.0 2 0 0 2 2 2 0 Interferon alpha/beta domain MbeD_MobD PF04899.12 AAG04487.1 - 4.4 7.5 11.2 1.8 8.8 1.5 3.6 3 1 0 3 3 3 0 MbeD/MobD like Med21 PF11221.8 AAG04487.1 - 7.2 6.9 8.6 0.73 10.1 2.8 2.1 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Sigma54_activat PF00158.26 AAG04488.1 - 2.6e-67 225.7 0.0 3.8e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAG04488.1 - 1.4e-25 89.6 0.0 2.7e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAG04488.1 - 3.1e-18 66.2 0.0 1e-17 64.6 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG04488.1 - 3.2e-13 49.2 1.1 1.1e-12 47.5 1.1 2.1 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAG04488.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAG04488.1 - 1.3e-05 24.4 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 AAG04488.1 - 0.00012 22.6 0.1 0.00027 21.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAG04488.1 - 0.00014 22.3 0.0 0.00022 21.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 AAG04488.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain FleQ PF06490.11 AAG04488.1 - 0.00073 19.9 0.0 0.002 18.4 0.0 1.7 2 0 0 2 2 1 1 Flagellar regulatory protein FleQ Mg_chelatase PF01078.21 AAG04488.1 - 0.0011 18.4 0.1 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AAG04488.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MerR PF00376.23 AAG04488.1 - 0.0019 17.9 0.8 0.0043 16.8 0.0 2.0 2 0 0 2 2 1 1 MerR family regulatory protein HTH_28 PF13518.6 AAG04488.1 - 0.0025 17.9 0.1 0.0074 16.4 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG04488.1 - 0.0057 16.4 0.3 0.015 15.1 0.3 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_20 PF12840.7 AAG04488.1 - 0.011 15.8 2.9 0.013 15.6 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_24 PF13412.6 AAG04488.1 - 0.015 14.8 1.1 0.15 11.7 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding ATPase PF06745.13 AAG04488.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC Sigma70_r4_2 PF08281.12 AAG04488.1 - 0.022 14.4 0.2 0.19 11.5 0.1 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 AAA_2 PF07724.14 AAG04488.1 - 0.027 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_11 PF08279.12 AAG04488.1 - 0.048 13.6 1.0 0.09 12.7 0.1 1.9 2 0 0 2 2 2 0 HTH domain HTH_1 PF00126.27 AAG04488.1 - 0.055 13.4 0.0 0.53 10.3 0.1 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_17 PF12728.7 AAG04488.1 - 0.077 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Mga PF08280.11 AAG04488.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_7 PF12775.7 AAG04488.1 - 0.15 11.6 0.0 0.45 10.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region FliE PF02049.18 AAG04489.1 - 8.3e-32 109.2 9.1 1e-31 108.9 9.1 1.2 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE DUF86 PF01934.17 AAG04489.1 - 0.0084 16.0 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF86 Rep_4 PF05797.11 AAG04489.1 - 0.057 12.5 0.4 0.067 12.3 0.4 1.0 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) FtsK_gamma PF09397.10 AAG04489.1 - 0.28 11.0 2.9 1.4 8.8 0.1 2.6 3 0 0 3 3 3 0 Ftsk gamma domain YscJ_FliF PF01514.17 AAG04490.1 - 3.8e-71 238.8 0.1 9.8e-71 237.4 0.0 1.7 2 0 0 2 2 2 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 AAG04490.1 - 4e-48 163.6 0.7 4e-48 163.6 0.7 2.2 2 0 0 2 2 2 1 Flagellar M-ring protein C-terminal DUF2209 PF09974.9 AAG04490.1 - 0.094 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) FliG_N PF14842.6 AAG04491.1 - 1.4e-44 150.9 6.0 1.5e-33 115.5 0.2 3.4 2 1 1 3 3 3 3 FliG N-terminal domain FliG_C PF01706.16 AAG04491.1 - 7e-44 148.4 9.5 6.3e-41 138.9 2.2 2.7 3 0 0 3 3 3 2 FliG C-terminal domain FliG_M PF14841.6 AAG04491.1 - 9.9e-31 105.8 3.4 5.5e-24 84.2 0.2 4.1 5 0 0 5 5 5 2 FliG middle domain MgtE_N PF03448.17 AAG04491.1 - 3.7e-09 37.1 8.5 0.0037 17.8 0.1 4.3 3 1 0 3 3 3 3 MgtE intracellular N domain ACCA PF03255.14 AAG04491.1 - 0.043 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FliH PF02108.16 AAG04492.1 - 3.6e-34 117.6 2.9 6e-34 116.9 2.9 1.3 1 0 0 1 1 1 1 Flagellar assembly protein FliH Yae1_N PF09811.9 AAG04492.1 - 0.014 15.1 0.5 0.022 14.4 0.5 1.3 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF4376 PF14301.6 AAG04492.1 - 0.023 15.1 0.7 0.085 13.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) PP2C_C PF07830.13 AAG04492.1 - 0.089 13.3 1.3 3.6 8.1 0.0 2.9 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain ATP-synt_ab PF00006.25 AAG04493.1 - 6.1e-74 248.3 0.0 7.8e-74 247.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AAG04493.1 - 8.1e-25 86.5 0.0 1.3e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 AAG04493.1 - 0.0047 17.4 0.1 0.014 15.9 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain CBP_BcsO PF17037.5 AAG04493.1 - 0.011 15.9 0.0 0.77 9.9 0.0 2.3 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsO ABC_tran PF00005.27 AAG04493.1 - 0.085 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FliJ PF02050.16 AAG04494.1 - 1.2e-36 125.6 23.7 1.4e-36 125.4 23.7 1.0 1 0 0 1 1 1 1 Flagellar FliJ protein YscO-like PF16789.5 AAG04494.1 - 0.00069 19.7 13.9 0.067 13.2 13.9 2.0 1 1 0 1 1 1 1 YscO-like protein DUF2408 PF10303.9 AAG04494.1 - 0.012 16.1 0.7 0.012 16.1 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Bcr-Abl_Oligo PF09036.10 AAG04494.1 - 0.017 15.1 0.1 0.017 15.1 0.1 2.0 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain YscO PF07321.12 AAG04494.1 - 0.44 10.5 23.2 0.77 9.7 4.8 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO CBF_beta PF02312.17 AAG04494.1 - 2.5 7.7 8.5 1.5 8.5 3.0 2.4 2 1 1 3 3 3 0 Core binding factor beta subunit Exonuc_VII_L PF02601.15 AAG04494.1 - 5.6 6.4 11.0 6.6 6.2 11.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit POTRA_TamA_1 PF17243.2 AAG04494.1 - 9.9 6.3 8.7 29 4.8 0.0 2.8 3 0 0 3 3 3 0 POTRA domain TamA domain 1 Gcw_chp PF09694.10 AAG04495.1 - 3.9e-14 53.2 0.1 7.4e-14 52.3 0.1 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (Gcw_chp) GGDEF PF00990.21 AAG04496.1 - 1.2e-46 158.4 0.0 1.7e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAG04496.1 - 0.0012 19.1 0.1 0.0024 18.1 0.1 1.6 1 0 0 1 1 1 1 GGDEF-like domain DUF202 PF02656.15 AAG04496.1 - 0.045 14.2 7.6 1.1 9.7 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Acyl_transf_3 PF01757.22 AAG04496.1 - 0.36 9.8 10.3 0.32 10.0 9.3 1.4 1 1 0 1 1 1 0 Acyltransferase family Zip PF02535.22 AAG04496.1 - 0.44 9.7 2.8 0.68 9.1 2.1 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter MFS_1 PF07690.16 AAG04497.1 - 8.3e-31 107.2 45.5 1.2e-30 106.7 45.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG04497.1 - 1.2e-07 31.0 5.0 1.2e-07 31.0 5.0 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 AAG04497.1 - 0.00019 20.2 1.2 0.00019 20.2 1.2 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein HTH_18 PF12833.7 AAG04498.1 - 1.6e-21 76.3 1.2 1.6e-21 76.3 1.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain AraC_binding PF02311.19 AAG04498.1 - 1.6e-18 66.9 0.1 2.9e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_AraC PF00165.23 AAG04498.1 - 1.6e-09 37.6 0.0 0.00096 19.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG04498.1 - 5e-05 22.9 0.0 8.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain S4 PF01479.25 AAG04499.1 - 4.7e-07 29.4 0.0 9.2e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.22 AAG04499.1 - 0.041 14.0 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 RNA pseudouridylate synthase DUF3335 PF11814.8 AAG04500.1 - 0.006 16.1 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase_C39 like family GSDH PF07995.11 AAG04501.1 - 1.2e-137 458.7 0.0 1.3e-137 458.5 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase ABC_membrane PF00664.23 AAG04502.1 - 8.8e-51 173.2 10.2 1.1e-50 172.8 10.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAG04502.1 - 5.2e-32 111.2 0.0 1e-31 110.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAG04502.1 - 2e-06 27.4 0.0 0.00052 19.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAG04502.1 - 3.4e-05 23.8 0.1 0.00074 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAG04502.1 - 7.7e-05 22.4 0.0 0.00021 21.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG04502.1 - 0.0024 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAG04502.1 - 0.0026 18.2 2.6 0.0057 17.1 0.9 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAG04502.1 - 0.0054 17.0 0.0 0.031 14.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAG04502.1 - 0.025 14.1 0.0 0.085 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAG04502.1 - 0.1 12.8 0.2 0.93 9.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 AAG04502.1 - 0.11 11.2 0.1 0.28 9.9 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 AAG04502.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAG04502.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arteri_Gl PF00951.18 AAG04502.1 - 2.9 7.7 5.8 0.56 10.0 1.2 2.2 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein LprI PF07007.12 AAG04503.1 - 0.00032 21.3 4.1 0.00069 20.2 3.1 1.8 1 1 1 2 2 2 2 Lysozyme inhibitor LprI Sulfatase PF00884.23 AAG04504.1 - 1.1e-36 126.9 0.0 1.5e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 AAG04504.1 - 9.5e-05 21.6 0.0 0.00021 20.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 AAG04504.1 - 0.0056 16.3 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 AAG04504.1 - 0.23 10.0 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) S1_2 PF13509.6 AAG04505.1 - 1.1e-34 118.3 0.0 2.5e-22 78.7 0.0 2.8 3 0 0 3 3 3 2 S1 domain CvfB_WH PF17783.1 AAG04505.1 - 2.3e-22 78.5 0.0 3.8e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 CvfB-like winged helix domain GntR PF00392.21 AAG04505.1 - 0.0055 16.3 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 Bacterial regulatory proteins, gntR family DUF863 PF05904.11 AAG04506.1 - 0.34 9.3 0.1 0.44 8.9 0.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) MgtE PF01769.16 AAG04507.1 - 0.00012 22.4 0.2 0.00017 21.9 0.2 1.1 1 0 0 1 1 1 1 Divalent cation transporter DUF4131 PF13567.6 AAG04507.1 - 0.066 12.9 0.5 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) OmpA PF00691.20 AAG04508.1 - 1.8e-20 73.1 0.1 2.5e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 OmpA family Pilus_CpaD PF09476.10 AAG04508.1 - 9.1e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) GGDEF PF00990.21 AAG04509.1 - 4.5e-47 159.8 0.1 8.5e-47 158.9 0.1 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE8 PF17152.4 AAG04509.1 - 5e-34 116.6 0.4 1.2e-33 115.3 0.4 1.7 1 0 0 1 1 1 1 Periplasmic sensor domain HAMP PF00672.25 AAG04509.1 - 1.3e-09 38.3 0.2 5.5e-09 36.3 0.2 2.2 1 0 0 1 1 1 1 HAMP domain DUF4872 PF16169.5 AAG04509.1 - 0.077 12.7 0.0 0.25 11.1 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4872) HxlR PF01638.17 AAG04509.1 - 0.13 12.1 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 HxlR-like helix-turn-helix DUF4154 PF13689.6 AAG04510.1 - 5.2e-32 111.0 0.0 6.1e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 YfiR/HmsC-like fn3_6 PF17766.1 AAG04510.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Fibronectin type-III domain Pep_deformylase PF01327.21 AAG04511.1 - 1.8e-34 118.6 0.0 2.1e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase DUF2025 PF09634.10 AAG04512.1 - 3.4e-59 197.3 0.1 3.8e-59 197.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2025) HD_assoc PF13286.6 AAG04513.1 - 4.9e-09 36.6 0.6 0.00099 19.6 0.2 3.1 2 1 1 3 3 3 2 Phosphohydrolase-associated domain HD PF01966.22 AAG04513.1 - 3.2e-08 33.8 0.0 9.1e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 HD domain SIR2 PF02146.17 AAG04514.1 - 1.1e-50 172.0 0.0 1.3e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 AAG04514.1 - 2.1e-06 27.5 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Tricorn_PDZ PF14685.6 AAG04514.1 - 0.043 13.8 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain zf-RRN7 PF11781.8 AAG04514.1 - 6.2 6.6 6.0 25 4.7 1.2 2.5 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4234 PF14018.6 AAG04515.1 - 7.1e-07 29.3 3.6 4.6e-05 23.5 3.6 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4234) Oxidored_q3 PF00499.20 AAG04515.1 - 0.00031 20.5 0.2 0.00056 19.6 0.2 1.4 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF3854 PF12965.7 AAG04515.1 - 0.19 11.7 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Aldo_ket_red PF00248.21 AAG04516.1 - 1.1e-73 248.1 0.0 1.2e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LysR_substrate PF03466.20 AAG04517.1 - 8.6e-44 149.4 1.5 1.2e-43 148.9 1.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04517.1 - 6.6e-18 64.4 0.3 1.1e-17 63.7 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Glyoxalase PF00903.25 AAG04518.1 - 1.1e-13 51.5 0.0 1.4e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG04518.1 - 3.4e-07 31.0 0.1 4.5e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AAG04518.1 - 0.0033 17.6 0.2 0.18 11.9 0.0 2.1 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAG04518.1 - 0.0041 17.4 0.1 0.49 10.7 0.1 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AAG04518.1 - 0.031 14.2 0.0 6.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain Glycos_transf_2 PF00535.26 AAG04519.1 - 6e-07 29.4 0.0 8.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAG04519.1 - 7e-06 26.1 0.0 9.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAG04519.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family group 2 MFS_1 PF07690.16 AAG04520.1 - 2e-46 158.6 69.1 3.1e-37 128.3 40.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG04520.1 - 2.5e-06 26.7 13.9 5.5e-06 25.5 8.7 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAG04520.1 - 0.00026 20.0 20.3 0.00075 18.5 9.6 2.1 1 1 1 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 AAG04520.1 - 0.00036 19.9 32.9 0.00099 18.5 32.6 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 AAG04520.1 - 0.022 13.7 0.5 0.05 12.5 0.5 1.6 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM GGDEF_2 PF17853.1 AAG04522.1 - 0.06 13.6 1.1 0.11 12.8 1.2 1.6 1 1 0 1 1 1 0 GGDEF-like domain DUF393 PF04134.12 AAG04523.1 - 2.1e-20 74.1 2.7 2.8e-20 73.8 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DJ-1_PfpI PF01965.24 AAG04524.1 - 3.9e-08 33.3 0.0 3.8e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 DJ-1/PfpI family ThiJ_like PF17124.5 AAG04524.1 - 0.0035 17.0 0.0 0.024 14.3 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like Tricorn_C1 PF14684.6 AAG04524.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain Autoind_bind PF03472.15 AAG04525.1 - 6.5e-25 87.4 0.3 1.2e-24 86.4 0.0 1.6 2 0 0 2 2 2 1 Autoinducer binding domain GerE PF00196.19 AAG04525.1 - 9.4e-18 63.5 0.5 1.4e-17 63.0 0.5 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG04525.1 - 1.4e-08 34.3 1.1 3.9e-08 32.8 1.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG04525.1 - 3e-05 23.4 1.7 3e-05 23.4 1.7 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_10 PF04967.12 AAG04525.1 - 0.0044 16.8 0.4 0.019 14.7 0.1 2.1 2 0 0 2 2 2 1 HTH DNA binding domain HTH_23 PF13384.6 AAG04525.1 - 0.016 15.0 0.9 0.053 13.3 0.9 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_ECF PF07638.11 AAG04525.1 - 0.017 15.0 0.5 0.028 14.3 0.5 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_28 PF13518.6 AAG04525.1 - 0.018 15.1 2.2 0.044 13.9 2.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AAG04525.1 - 0.097 12.5 0.3 0.27 11.0 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ADH_zinc_N_2 PF13602.6 AAG04526.1 - 1.9e-26 93.7 0.4 4.2e-26 92.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AAG04526.1 - 2.2e-23 82.6 0.8 9e-23 80.7 0.8 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG04526.1 - 6.4e-10 38.9 0.0 2.3e-09 37.1 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain LysR_substrate PF03466.20 AAG04527.1 - 2.1e-36 125.3 6.2 3.7e-36 124.5 6.2 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04527.1 - 1.2e-15 57.2 0.7 2.6e-15 56.1 0.7 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG04527.1 - 0.02 14.7 0.3 0.066 13.0 0.3 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG04527.1 - 0.037 13.9 0.6 0.037 13.9 0.6 2.5 3 0 0 3 3 3 0 MarR family HTH_Tnp_ISL3 PF13542.6 AAG04527.1 - 0.12 11.8 0.2 0.12 11.8 0.2 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 CAP PF00188.26 AAG04528.1 - 3.8e-22 79.4 0.1 4.4e-20 72.8 0.1 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Cupin_2 PF07883.11 AAG04529.1 - 4.8e-23 80.7 0.2 1e-12 47.6 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 AAG04529.1 - 6.2e-12 45.0 0.1 2.4e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 AAG04529.1 - 9.7e-08 32.0 0.2 0.018 15.0 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 AAG04529.1 - 1.2e-06 28.6 0.0 3.8e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_1 PF00190.22 AAG04529.1 - 0.00049 19.7 0.1 1.3 8.7 0.0 2.6 2 1 0 2 2 2 2 Cupin EutQ PF06249.12 AAG04529.1 - 0.077 12.7 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ LysR_substrate PF03466.20 AAG04530.1 - 3.8e-29 101.6 3.3 6.1e-29 100.9 3.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04530.1 - 3.6e-19 68.4 1.9 4.1e-19 68.3 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG04530.1 - 0.00049 19.9 0.3 0.0011 18.7 0.3 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AAG04530.1 - 0.0016 18.5 0.2 0.006 16.6 0.2 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG04530.1 - 0.02 14.8 0.8 0.062 13.2 0.2 2.1 2 0 0 2 2 2 0 MarR family HTH_50 PF18024.1 AAG04530.1 - 0.04 13.5 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain UTRA PF07702.13 AAG04531.1 - 2.7e-37 127.7 0.1 3.6e-37 127.4 0.1 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAG04531.1 - 3.6e-19 68.2 0.5 6.4e-19 67.4 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAG04531.1 - 0.00038 20.4 0.2 0.0011 18.9 0.3 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 AAG04531.1 - 0.085 12.8 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 AAG04531.1 - 0.11 12.4 0.0 0.7 9.8 0.0 2.0 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HAD PF12710.7 AAG04532.1 - 4.1e-36 125.2 2.1 4.8e-36 124.9 2.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1707 PF08044.11 AAG04532.1 - 0.021 14.9 3.3 0.03 14.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) MFS_1 PF07690.16 AAG04533.1 - 1.2e-48 165.9 68.7 2.8e-42 144.9 39.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG04533.1 - 0.0049 16.2 11.2 0.0049 16.2 11.2 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Nuc_H_symport PF03825.16 AAG04533.1 - 0.17 10.9 23.4 0.019 14.0 4.5 3.5 2 2 1 3 3 3 0 Nucleoside H+ symporter LysR_substrate PF03466.20 AAG04534.1 - 4.2e-34 117.8 5.0 5.3e-34 117.4 5.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04534.1 - 1.3e-19 69.9 0.0 3.5e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AAG04534.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 AAG04534.1 - 0.076 13.2 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain Fe-ADH PF00465.19 AAG04535.1 - 1.4e-109 366.3 0.0 1.6e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AAG04535.1 - 8.9e-17 61.6 0.0 1.2e-08 35.0 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase AA_permease_2 PF13520.6 AAG04536.1 - 6.8e-41 140.5 37.7 8.7e-41 140.1 37.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAG04536.1 - 8.8e-22 77.3 31.0 1.8e-21 76.3 31.0 1.5 1 1 0 1 1 1 1 Amino acid permease Exotox-A_bind PF09101.10 AAG04537.1 - 1.7e-121 404.5 0.0 2.2e-121 404.2 0.0 1.1 1 0 0 1 1 1 1 Exotoxin A binding Exotox-A_cataly PF09009.10 AAG04537.1 - 7.7e-77 256.8 0.0 1.5e-76 255.9 0.0 1.5 1 0 0 1 1 1 1 Exotoxin A catalytic Exotox-A_target PF09102.10 AAG04537.1 - 1.3e-70 236.0 2.5 1.3e-70 236.0 2.5 1.7 2 0 0 2 2 2 1 Exotoxin A, targeting DUF2195 PF09961.9 AAG04538.1 - 3.1e-37 127.1 0.1 3.5e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2195) Pyocin_S PF06958.12 AAG04539.1 - 1.1e-35 123.1 5.2 2.4e-35 122.1 5.2 1.6 1 0 0 1 1 1 1 S-type Pyocin Cloacin PF03515.14 AAG04539.1 - 0.0027 17.5 6.0 0.005 16.6 6.0 1.4 1 0 0 1 1 1 1 Colicin-like bacteriocin tRNase domain DASH_Spc34 PF08657.10 AAG04539.1 - 4.2 7.1 11.0 3.7 7.3 9.0 1.9 1 1 1 2 2 2 0 DASH complex subunit Spc34 Fib_alpha PF08702.10 AAG04539.1 - 4.7 7.4 11.6 1.3 9.3 2.4 3.1 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Colicin_Pyocin PF01320.18 AAG04540.1 - 9.3e-37 125.0 1.0 1e-36 124.9 1.0 1.0 1 0 0 1 1 1 1 Colicin immunity protein / pyocin immunity protein VitD-bind_III PF09164.10 AAG04540.1 - 0.11 12.5 2.1 0.22 11.5 2.1 1.5 1 1 0 1 1 1 0 Vitamin D binding protein, domain III Bro-N PF02498.17 AAG04542.1 - 1.6e-05 25.5 0.0 7.1e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 BRO family, N-terminal domain Y1_Tnp PF01797.16 AAG04543.1 - 2.2e-07 31.0 0.1 2.6e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Transposase IS200 like Ribonuc_red_sm PF00268.21 AAG04544.1 - 9.4e-87 291.0 0.3 1.2e-86 290.7 0.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PPP5 PF08321.12 AAG04544.1 - 0.057 13.7 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 PPP5 TPR repeat region Ribonuc_red_lgC PF02867.15 AAG04545.1 - 1.8e-182 607.6 0.0 2.2e-182 607.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 AAG04545.1 - 2e-29 102.0 1.2 2.8e-18 66.3 0.3 3.2 3 0 0 3 3 3 2 ATP cone domain Ribonuc_red_lgN PF00317.21 AAG04545.1 - 2.6e-22 78.6 0.1 6.8e-22 77.3 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Trans_reg_C PF00486.28 AAG04546.1 - 8.3e-25 86.7 0.2 1.9e-24 85.5 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAG04546.1 - 2.7e-23 82.2 0.0 4.4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain DUF2786 PF10979.8 AAG04546.1 - 0.26 11.2 1.9 0.31 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) HATPase_c PF02518.26 AAG04547.1 - 1.3e-22 80.4 0.0 3.1e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAG04547.1 - 4.3e-13 49.4 4.0 6.7e-13 48.8 2.1 2.3 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AAG04547.1 - 3.5e-11 43.0 2.0 4.5e-11 42.6 0.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAG04547.1 - 0.00014 21.8 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAG04547.1 - 0.0025 17.7 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CSD PF00313.22 AAG04548.1 - 1.3e-27 95.4 0.9 1.4e-27 95.3 0.9 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAG04548.1 - 0.0076 15.9 0.1 0.008 15.8 0.1 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain Methyltransf_25 PF13649.6 AAG04550.1 - 5.2e-11 43.1 0.0 2.1e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG04550.1 - 4.7e-10 40.0 0.0 1.8e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG04550.1 - 6e-07 29.4 0.0 1e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG04550.1 - 7.8e-07 29.1 0.1 1.5e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG04550.1 - 9.4e-06 26.3 0.0 2.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AAG04550.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG04550.1 - 0.00072 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 AAG04550.1 - 0.064 13.2 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 AAG04550.1 - 0.064 12.8 0.0 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Peptidase_M20 PF01546.28 AAG04551.1 - 3.9e-41 141.0 0.1 4.7e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAG04551.1 - 5.8e-28 97.0 0.2 1.4e-27 95.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain BNR_2 PF13088.6 AAG04551.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain Glyco_tranf_2_3 PF13641.6 AAG04552.1 - 9.3e-32 110.7 0.1 2.3e-31 109.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AAG04552.1 - 1.7e-28 99.6 0.1 4.5e-28 98.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAG04552.1 - 1.3e-23 84.0 0.6 1.3e-23 84.0 0.6 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAG04552.1 - 1.2e-09 37.9 0.0 2.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 AAG04552.1 - 6.7e-06 25.0 0.0 0.044 12.4 0.0 3.1 3 0 0 3 3 3 2 Chitin synthase Glyco_hydro_17 PF00332.18 AAG04552.1 - 0.00036 20.2 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Cellulose_synt PF03552.14 AAG04552.1 - 0.00042 19.0 0.1 0.00063 18.4 0.1 1.2 1 0 0 1 1 1 1 Cellulose synthase PMP22_Claudin PF00822.20 AAG04552.1 - 0.12 12.3 1.2 0.24 11.2 0.7 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family ThiF PF00899.21 AAG04553.1 - 4.3e-42 144.2 0.2 5.1e-42 143.9 0.2 1.1 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.18 AAG04553.1 - 0.0046 16.9 0.4 0.0068 16.3 0.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AAG04553.1 - 0.005 17.1 3.5 0.038 14.2 3.5 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 AAG04553.1 - 0.0094 15.2 0.3 0.011 14.9 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 AAG04553.1 - 0.011 16.1 6.6 0.026 14.9 3.2 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding 4PPT_N PF17837.1 AAG04554.1 - 2e-22 79.1 1.5 3.3e-22 78.4 1.5 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 AAG04554.1 - 1.9e-09 37.6 0.0 3.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily QH-AmDH_gamma PF08992.11 AAG04554.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit DLH PF01738.18 AAG04555.1 - 6e-46 156.7 0.1 6.9e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAG04555.1 - 4.7e-09 36.0 0.1 0.00024 20.6 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 AAG04555.1 - 2e-06 27.9 0.2 0.0028 17.6 0.0 2.7 2 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AAG04555.1 - 5.9e-06 25.7 2.1 0.0055 16.0 0.1 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 AAG04555.1 - 7.4e-05 22.7 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 AAG04555.1 - 7.5e-05 22.5 0.0 0.021 14.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Propep_M14 PF02244.16 AAG04555.1 - 0.02 15.3 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Alginate_lyase2 PF08787.11 AAG04556.1 - 5.7e-52 176.9 0.0 6.4e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Lipoxygenase PF00305.19 AAG04558.1 - 1.4e-59 202.2 0.0 3.2e-59 201.0 0.0 1.4 1 1 0 1 1 1 1 Lipoxygenase TerC PF03741.16 AAG04559.1 - 4.6e-44 150.3 11.0 4.6e-44 150.3 11.0 1.4 2 0 0 2 2 2 1 Integral membrane protein TerC family MarC PF01914.17 AAG04559.1 - 0.0034 16.8 0.7 0.0034 16.8 0.7 2.3 1 1 2 3 3 3 1 MarC family integral membrane protein DUF1700 PF08006.11 AAG04559.1 - 5.3 6.5 10.7 20 4.7 7.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) SLT_2 PF13406.6 AAG04560.1 - 5.4e-104 347.5 0.0 6.8e-104 347.2 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain PG_binding_1 PF01471.18 AAG04560.1 - 4.9e-11 42.7 1.2 6.6e-11 42.3 0.2 1.8 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 AAG04560.1 - 0.0029 17.8 0.5 0.029 14.6 0.1 2.3 1 1 1 2 2 2 1 Predicted Peptidoglycan domain PepSY_2 PF13670.6 AAG04560.1 - 0.019 15.0 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain FG-GAP PF01839.23 AAG04560.1 - 0.021 14.9 0.4 0.054 13.6 0.4 1.7 1 0 0 1 1 1 0 FG-GAP repeat Cytochrom_NNT PF03264.14 AAG04561.1 - 2.3e-76 255.4 3.7 2.6e-76 255.2 3.7 1.0 1 0 0 1 1 1 1 NapC/NirT cytochrome c family, N-terminal region Cytochrom_c3_2 PF14537.6 AAG04561.1 - 1.4e-06 28.7 11.1 0.0042 17.5 1.4 2.3 2 0 0 2 2 2 2 Cytochrome c3 Paired_CXXCH_1 PF09699.10 AAG04561.1 - 2e-06 27.4 8.0 0.015 15.0 1.3 3.6 3 1 0 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AAG04561.1 - 8.2e-06 25.7 16.4 0.001 19.0 4.6 3.0 1 1 2 3 3 3 3 Cytochrome c7 and related cytochrome c Cytochrom_CIII PF02085.16 AAG04561.1 - 5.6e-05 23.4 11.5 0.018 15.3 2.6 2.4 2 1 0 2 2 2 2 Class III cytochrome C family zf-C2HE PF16278.5 AAG04561.1 - 0.018 15.5 3.1 4 7.9 0.5 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Neuropep_like PF15161.6 AAG04561.1 - 0.095 12.4 0.7 0.095 12.4 0.7 3.3 3 1 1 4 4 4 0 Neuropeptide-like Cytochrome_P460 PF16694.5 AAG04561.1 - 0.27 11.6 16.2 4.3 7.7 0.3 4.0 2 2 2 4 4 4 0 Cytochrome P460 DHC PF09626.10 AAG04561.1 - 0.36 11.7 0.3 0.36 11.7 0.3 3.6 1 1 1 3 3 3 0 Dihaem cytochrome c zinc_ribbon_9 PF14369.6 AAG04561.1 - 0.85 9.9 10.7 5.8 7.3 0.1 4.0 3 1 1 4 4 4 0 zinc-ribbon HNH PF01844.23 AAG04561.1 - 2.2 8.6 14.8 6.9 6.9 0.2 4.1 4 0 0 4 4 4 0 HNH endonuclease zf-dskA_traR PF01258.17 AAG04561.1 - 3.3 7.7 7.5 8.3 6.4 0.0 3.7 4 1 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger NapB PF03892.14 AAG04562.1 - 3e-46 156.5 0.3 3.7e-46 156.3 0.3 1.1 1 0 0 1 1 1 1 Nitrate reductase cytochrome c-type subunit (NapB) Paired_CXXCH_1 PF09699.10 AAG04562.1 - 0.00047 19.8 0.7 0.0019 17.9 0.8 1.9 1 1 0 1 1 1 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AAG04562.1 - 0.0013 18.7 0.2 0.002 18.1 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c Cytochrom_NNT PF03264.14 AAG04562.1 - 0.0057 16.4 2.8 0.027 14.2 3.0 1.8 1 1 1 2 2 2 2 NapC/NirT cytochrome c family, N-terminal region Cytochrom_c3_2 PF14537.6 AAG04562.1 - 0.013 15.9 1.0 0.04 14.4 1.0 1.7 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_P460 PF16694.5 AAG04562.1 - 0.032 14.6 0.2 7.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome P460 DUF3365 PF11845.8 AAG04562.1 - 0.037 14.3 0.9 1.9 8.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) Cytochrome_C554 PF13435.6 AAG04562.1 - 0.051 14.5 0.8 12 6.9 0.1 2.2 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Cytochrom_CIII PF02085.16 AAG04562.1 - 0.096 13.0 1.1 0.23 11.8 1.2 1.5 1 1 0 1 1 1 0 Class III cytochrome C family DZR PF12773.7 AAG04562.1 - 0.15 12.1 1.7 0.44 10.6 1.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon TraW_N PF12477.8 AAG04562.1 - 1.3 9.1 5.4 2.1 8.4 5.4 1.4 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Molybdopterin PF00384.22 AAG04563.1 - 1.4e-86 291.1 0.0 1.8e-86 290.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAG04563.1 - 2.6e-25 88.6 0.1 1e-24 86.7 0.0 2.1 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAG04563.1 - 9.7e-15 54.3 0.8 2.3e-14 53.1 0.8 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain NapD PF03927.13 AAG04564.1 - 1.3e-25 89.3 0.0 1.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 NapD protein Fer4_7 PF12838.7 AAG04565.1 - 2.6e-16 59.9 19.2 5.2e-09 36.6 4.5 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG04565.1 - 3.1e-14 52.9 22.3 2.5e-07 30.7 5.9 2.6 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAG04565.1 - 5e-11 41.9 33.7 2.9e-05 23.7 1.3 4.2 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_10 PF13237.6 AAG04565.1 - 1.6e-10 40.9 22.1 3e-05 24.1 8.0 3.2 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG04565.1 - 1.8e-10 41.1 15.9 0.013 16.0 1.1 4.1 4 0 0 4 4 4 4 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG04565.1 - 1.4e-09 38.7 21.0 0.0027 18.6 1.8 4.1 4 0 0 4 4 4 4 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAG04565.1 - 1.9e-09 37.5 19.4 6.3e-06 26.2 5.4 3.2 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG04565.1 - 3.2e-09 37.2 17.9 0.018 15.6 0.2 4.1 4 0 0 4 4 4 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG04565.1 - 7e-08 32.4 32.8 0.014 15.9 1.9 4.2 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_2 PF12797.7 AAG04565.1 - 1.1e-07 31.5 33.9 0.00029 20.7 2.3 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_6 PF12837.7 AAG04565.1 - 8.3e-07 28.8 37.7 0.00049 20.1 2.7 4.2 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_3 PF12798.7 AAG04565.1 - 0.077 14.0 44.6 0.14 13.2 7.3 4.4 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_15 PF13459.6 AAG04565.1 - 0.13 13.1 0.7 0.13 13.1 0.7 3.8 3 1 1 4 4 4 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 AAG04565.1 - 1.1 10.2 25.6 0.54 11.1 1.0 3.9 4 0 0 4 4 4 0 4Fe-4S dicluster domain NapE PF06796.11 AAG04566.1 - 1.4e-24 85.4 0.3 1.5e-24 85.3 0.3 1.0 1 0 0 1 1 1 1 Periplasmic nitrate reductase protein NapE Apq12 PF12716.7 AAG04566.1 - 0.032 14.2 2.1 0.039 13.9 2.1 1.1 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis OMP_b-brl PF13505.6 AAG04567.1 - 1e-09 38.8 8.1 1.5e-09 38.2 8.1 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Response_reg PF00072.24 AAG04568.1 - 1.4e-26 92.9 0.0 2.7e-26 91.9 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG04568.1 - 3.9e-24 84.5 0.1 9.6e-24 83.3 0.1 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HTH_11 PF08279.12 AAG04568.1 - 0.19 11.7 0.4 17 5.5 0.0 2.7 3 0 0 3 3 3 0 HTH domain HATPase_c PF02518.26 AAG04569.1 - 1e-08 35.7 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG04569.1 - 1.4e-05 25.0 4.2 2.9e-05 24.0 0.0 3.3 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAG04569.1 - 0.0012 18.7 0.0 12 5.9 0.0 3.2 3 0 0 3 3 3 2 GHKL domain PhoQ_Sensor PF08918.10 AAG04569.1 - 0.0041 17.0 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 PhoQ Sensor CorA PF01544.18 AAG04569.1 - 0.02 14.2 0.2 0.038 13.3 0.2 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein HATPase_c_2 PF13581.6 AAG04569.1 - 0.026 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain EAL PF00563.20 AAG04570.1 - 1.1e-64 218.3 0.1 9.4e-64 215.2 0.0 2.1 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AAG04570.1 - 4.4e-43 146.8 0.1 9.1e-43 145.8 0.1 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAG04570.1 - 2.2e-35 120.8 0.0 1.5e-16 60.5 0.1 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 AAG04570.1 - 3e-22 78.8 1.1 7.7e-10 38.8 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AAG04570.1 - 3.3e-22 78.7 0.1 4.3e-10 39.8 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 AAG04570.1 - 3.1e-20 72.5 12.2 1.2e-11 44.8 0.1 5.1 6 0 0 6 6 6 3 PAS fold MASE1 PF05231.14 AAG04570.1 - 1.8e-17 63.5 38.7 2.6e-17 62.9 38.7 1.2 1 0 0 1 1 1 1 MASE1 PAS_8 PF13188.7 AAG04570.1 - 1.1e-12 47.6 0.3 1.3e-05 25.1 0.1 3.1 2 0 0 2 2 2 2 PAS domain PAS_6 PF08348.11 AAG04570.1 - 0.0071 16.2 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 YheO-like PAS domain GGDEF_2 PF17853.1 AAG04570.1 - 0.34 11.2 5.2 2 8.7 0.4 4.1 3 2 0 3 3 3 0 GGDEF-like domain Arabinose_bd PF12625.7 AAG04571.1 - 4.4e-48 163.9 5.2 4.4e-48 163.9 5.2 1.5 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG04571.1 - 1.5e-19 70.0 1.0 8.1e-19 67.7 0.4 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04571.1 - 4.8e-17 61.6 0.0 5.2e-11 42.4 0.0 2.8 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r4_2 PF08281.12 AAG04571.1 - 3.2e-05 23.5 0.2 0.35 10.6 0.0 3.5 5 0 0 5 5 5 2 Sigma-70, region 4 HTH_23 PF13384.6 AAG04571.1 - 3.2e-05 23.6 0.0 0.22 11.3 0.0 2.9 1 1 1 2 2 2 2 Homeodomain-like domain HTH_IclR PF09339.10 AAG04571.1 - 0.0011 18.7 0.5 1.7 8.5 0.0 3.5 3 0 0 3 3 3 1 IclR helix-turn-helix domain SurA_N PF09312.11 AAG04571.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 SurA N-terminal domain HTH_24 PF13412.6 AAG04571.1 - 0.0017 17.9 0.0 0.89 9.2 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAG04571.1 - 0.0035 17.2 0.3 1.8 8.5 0.0 3.0 2 1 0 2 2 2 1 MarR family HTH_28 PF13518.6 AAG04571.1 - 0.0087 16.2 0.4 0.42 10.8 0.2 3.2 2 1 1 3 3 3 1 Helix-turn-helix domain TetR_N PF00440.23 AAG04571.1 - 0.017 14.9 0.0 0.3 10.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 AAG04571.1 - 0.018 14.5 0.0 8.4 5.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AAG04571.1 - 0.025 14.3 5.2 2.5 7.9 0.0 3.5 4 0 0 4 4 3 0 Helix-turn-helix domain HTH_10 PF04967.12 AAG04571.1 - 0.028 14.2 0.0 9.3 6.2 0.0 2.9 2 0 0 2 2 2 0 HTH DNA binding domain HTH_5 PF01022.20 AAG04571.1 - 0.047 13.5 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAG04571.1 - 0.063 13.4 0.7 2.4 8.3 0.2 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 AAG04571.1 - 0.068 13.6 0.0 53 4.4 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AAG04571.1 - 0.071 13.0 1.1 5.7 6.9 0.0 3.0 3 0 0 3 3 2 0 AsnC-type helix-turn-helix domain HTH_22 PF13309.6 AAG04571.1 - 0.078 13.1 0.0 18 5.5 0.0 2.4 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 AAG04571.1 - 0.08 12.8 1.2 1.8 8.4 0.6 3.3 3 1 1 4 4 3 0 PucR C-terminal helix-turn-helix domain HTH_17 PF12728.7 AAG04571.1 - 0.084 13.1 0.0 8.2 6.7 0.0 3.3 4 0 0 4 4 3 0 Helix-turn-helix domain HTH_8 PF02954.19 AAG04571.1 - 0.1 12.4 0.2 2.1 8.2 0.0 2.9 4 0 0 4 4 3 0 Bacterial regulatory protein, Fis family HTH_DeoR PF08220.12 AAG04571.1 - 0.11 12.3 0.1 12 5.7 0.0 2.7 2 1 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAG04571.1 - 0.12 12.4 0.1 21 5.1 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_32 PF13565.6 AAG04571.1 - 0.54 10.9 4.1 4.9 7.8 0.9 2.8 2 1 0 2 2 2 0 Homeodomain-like domain SDF PF00375.18 AAG04572.1 - 1.4e-113 379.9 35.7 1.5e-113 379.7 35.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family LysR_substrate PF03466.20 AAG04573.1 - 8.9e-34 116.7 11.8 1.6e-33 115.8 11.8 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04573.1 - 4.1e-18 65.1 2.4 1.2e-17 63.6 2.4 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family P22_Cro PF14549.6 AAG04573.1 - 0.0097 15.7 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro HTH_30 PF13556.6 AAG04573.1 - 0.023 14.5 0.2 0.048 13.5 0.2 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG04573.1 - 0.052 13.4 0.3 0.16 11.9 0.3 1.8 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 AAG04573.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family GST_N PF02798.20 AAG04574.1 - 5.2e-17 62.0 0.0 8.8e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAG04574.1 - 3.1e-15 56.3 0.0 5.7e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG04574.1 - 3.7e-14 52.8 0.0 6.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG04574.1 - 7.6e-12 45.3 0.0 1.5e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAG04574.1 - 2.8e-08 33.6 0.5 4.6e-08 33.0 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG04574.1 - 5.9e-06 26.4 0.0 9.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AAG04574.1 - 0.027 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bac_luciferase PF00296.20 AAG04575.1 - 1.4e-37 129.8 3.6 2e-37 129.3 3.6 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Acyl-CoA_dh_1 PF00441.24 AAG04576.1 - 3.9e-40 137.5 1.1 5.8e-40 136.9 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG04576.1 - 1.5e-30 106.2 0.3 1.2e-29 103.3 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG04576.1 - 2.3e-24 85.4 0.0 4.3e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG04576.1 - 5.7e-15 55.8 0.2 9.2e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CoA_transf_3 PF02515.17 AAG04577.1 - 6.3e-101 338.1 0.0 7.1e-101 338.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SprT-like PF10263.9 AAG04578.1 - 4.3e-18 65.2 0.0 5.8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 AAG04578.1 - 2.4e-10 40.1 7.0 5.9e-10 38.9 7.0 1.7 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Cu-oxidase_2 PF07731.14 AAG04578.1 - 0.095 12.4 0.3 0.11 12.2 0.3 1.3 1 1 0 1 1 1 0 Multicopper oxidase Peptidase_M1 PF01433.20 AAG04578.1 - 0.2 11.2 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain DUF1282 PF06930.12 AAG04579.1 - 2.4e-54 183.7 11.7 2.9e-54 183.4 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Yip1 PF04893.17 AAG04579.1 - 1.6e-33 115.8 13.8 1.6e-33 115.8 13.8 1.7 1 1 0 1 1 1 1 Yip1 domain DUF5373 PF17343.2 AAG04579.1 - 0.33 10.8 7.9 4.7 7.0 4.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5373) Jiraiya PF15038.6 AAG04579.1 - 2.9 7.3 11.1 0.059 12.8 3.5 1.9 2 1 0 2 2 2 0 Jiraiya DNAJ_related PF12339.8 AAG04580.1 - 4e-43 146.7 1.4 5.5e-43 146.3 1.4 1.2 1 0 0 1 1 1 1 DNA-J related protein DnaJ PF00226.31 AAG04580.1 - 7.6e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ATP_bind_3 PF01171.20 AAG04581.1 - 5.1e-14 52.4 0.0 7.6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Adenine_glyco PF03352.13 AAG04582.1 - 2.7e-18 66.4 0.0 4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Methyladenine glycosylase AA_permease_2 PF13520.6 AAG04583.1 - 3.4e-61 207.4 39.9 3.4e-61 207.4 39.9 1.4 1 1 1 2 2 2 1 Amino acid permease Amidinotransf PF02274.17 AAG04584.1 - 3.2e-18 65.9 0.0 3e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 Amidinotransferase AP_endonuc_2 PF01261.24 AAG04584.1 - 0.097 12.1 0.0 8 5.8 0.0 2.8 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel Sigma54_activat PF00158.26 AAG04585.1 - 1.8e-59 200.2 0.0 3e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG04585.1 - 4.3e-17 62.5 0.0 1.3e-16 60.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain PAS_4 PF08448.10 AAG04585.1 - 1.7e-16 60.4 0.1 4.1e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 PAS fold HTH_8 PF02954.19 AAG04585.1 - 3.7e-10 39.4 3.9 8.5e-10 38.3 3.9 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAG04585.1 - 1.6e-08 34.6 0.0 3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG04585.1 - 6.1e-05 22.5 0.1 0.01 15.2 0.1 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAG04585.1 - 0.00012 22.5 0.0 0.00027 21.4 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HTH_50 PF18024.1 AAG04585.1 - 0.00067 19.2 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain PAS PF00989.25 AAG04585.1 - 0.00088 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold HTH_30 PF13556.6 AAG04585.1 - 0.0022 17.7 0.9 0.014 15.1 0.6 2.3 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain SIR2 PF02146.17 AAG04586.1 - 3e-37 128.3 0.0 3.8e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family HAD PF12710.7 AAG04586.1 - 0.056 13.8 0.1 1 9.8 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-RRN7 PF11781.8 AAG04586.1 - 0.76 9.5 3.1 12 5.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 NLPC_P60 PF00877.19 AAG04587.1 - 7.6e-30 103.0 0.0 1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 AAG04587.1 - 4.2e-05 23.7 0.0 0.05 13.7 0.0 2.2 2 0 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF1175 PF06672.11 AAG04587.1 - 0.002 17.9 0.0 0.06 13.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1175) LRAT PF04970.13 AAG04587.1 - 0.0037 17.6 0.0 0.009 16.3 0.0 1.6 2 0 0 2 2 2 1 Lecithin retinol acyltransferase Amidase_5 PF05382.13 AAG04587.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase NLPC_P60 PF00877.19 AAG04588.1 - 6.2e-30 103.3 0.0 7.6e-30 103.0 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 AAG04588.1 - 0.00041 20.5 0.0 0.2 11.7 0.0 2.3 1 1 1 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF1175 PF06672.11 AAG04588.1 - 0.014 15.1 0.0 0.84 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) LRAT PF04970.13 AAG04588.1 - 0.026 14.8 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Methyltransf_3 PF01596.17 AAG04589.1 - 1.2e-62 210.9 0.0 1.3e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 AAG04589.1 - 4e-17 63.2 0.0 5.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAG04589.1 - 0.00067 19.5 0.0 0.00093 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LysR_substrate PF03466.20 AAG04590.1 - 4.3e-49 166.7 0.8 4.3e-49 166.7 0.8 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04590.1 - 1.1e-19 70.1 0.1 3.4e-19 68.6 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF746 PF05344.11 AAG04590.1 - 0.03 14.1 0.1 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) RDM PF11002.8 AAG04590.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 RFPL defining motif (RDM) HTH_30 PF13556.6 AAG04590.1 - 0.068 13.0 0.3 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG04590.1 - 0.33 10.9 1.9 0.65 9.9 0.1 2.4 3 0 0 3 3 3 0 MarR family Isochorismatase PF00857.20 AAG04591.1 - 2.4e-22 79.9 0.0 5.4e-22 78.8 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family ATP-synt_G PF04718.15 AAG04591.1 - 0.0075 17.1 0.0 11 6.9 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial ATP synthase g subunit OsmC PF02566.19 AAG04592.1 - 1.9e-20 73.2 0.0 2.3e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein FMN_red PF03358.15 AAG04593.1 - 2.9e-39 134.3 0.0 3.7e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AAG04593.1 - 6.2e-07 29.3 0.0 8.7e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Pirin PF02678.16 AAG04594.1 - 1.2e-30 105.6 0.2 1.9e-30 105.0 0.2 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 AAG04594.1 - 1.4e-23 83.2 0.0 3.6e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Pirin C-terminal cupin domain DUF1857 PF08982.11 AAG04595.1 - 1.3e-24 86.7 0.0 1.7e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Na_H_Exchanger PF00999.21 AAG04596.1 - 3.1e-70 236.9 41.1 4.2e-70 236.5 41.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AAG04596.1 - 3.7e-25 88.5 0.0 8.7e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAG04596.1 - 0.024 14.0 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CTP_transf_like PF01467.26 AAG04596.1 - 0.047 13.9 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase-like LpxB PF02684.15 AAG04596.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase NAD_binding_7 PF13241.6 AAG04596.1 - 0.081 13.4 0.0 0.78 10.2 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 AAG04597.1 - 2.7e-09 36.0 0.0 1.1e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 AAG04597.1 - 5.2e-09 35.8 0.0 6e-08 32.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAG04597.1 - 1.1e-08 34.7 0.0 0.017 14.4 0.0 3.9 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG04597.1 - 2.5e-08 34.0 0.0 3.2e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 AAG04597.1 - 1.5e-07 30.9 0.0 5.1e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AAG04597.1 - 1.4e-06 27.8 0.2 2.5e-05 23.7 0.0 2.4 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 AAG04597.1 - 2e-05 24.4 2.3 0.00051 19.7 0.4 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAG04597.1 - 2e-05 25.0 0.8 0.029 14.9 0.0 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 AAG04597.1 - 0.00012 22.2 0.0 0.056 13.5 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 AAG04597.1 - 0.0015 19.0 0.2 0.016 15.6 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 AAG04597.1 - 0.0039 17.2 1.0 0.43 10.6 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 AAG04597.1 - 0.013 14.6 0.8 0.032 13.3 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 AAG04597.1 - 0.014 14.7 0.8 0.044 13.1 0.4 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 AAG04597.1 - 0.031 13.4 0.4 1.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AAG04597.1 - 0.037 13.1 0.2 3.2 6.7 0.1 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein MCRA PF06100.11 AAG04597.1 - 0.069 11.9 0.1 0.14 11.0 0.0 1.4 2 0 0 2 2 2 0 MCRA family FAD_binding_3 PF01494.19 AAG04597.1 - 0.18 11.0 0.4 0.87 8.8 0.2 2.2 3 0 0 3 3 3 0 FAD binding domain SNARE_assoc PF09335.11 AAG04598.1 - 2.1e-14 54.0 7.7 4.4e-14 53.0 5.7 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein Rhodanese PF00581.20 AAG04598.1 - 6.8e-09 36.2 0.0 1.1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain MLANA PF14991.6 AAG04598.1 - 0.052 13.8 0.2 0.098 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein melan-A Pirin PF02678.16 AAG04599.1 - 1.9e-37 127.6 0.2 2.6e-37 127.1 0.2 1.2 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 AAG04599.1 - 5.5e-22 77.7 0.1 1.1e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 AAG04599.1 - 1.6e-05 24.5 0.5 6.1e-05 22.6 0.2 2.2 2 1 1 3 3 3 1 Cupin domain Pirin_C PF05726.13 AAG04599.1 - 0.0022 18.3 0.1 0.037 14.4 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Abhydrolase_6 PF12697.7 AAG04600.1 - 8.5e-09 36.3 9.3 1.2e-08 35.8 9.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG04600.1 - 3.4e-06 26.9 0.0 0.00024 20.8 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG04600.1 - 5.3e-05 22.6 0.1 0.0077 15.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 AAG04600.1 - 0.00039 20.3 0.3 0.00059 19.7 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 AAG04600.1 - 0.001 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 AAG04600.1 - 0.0033 17.6 0.2 0.0047 17.1 0.2 1.4 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 AAG04600.1 - 0.004 17.1 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 AAG04600.1 - 0.017 14.7 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 AAG04600.1 - 0.035 13.8 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 AAG04600.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 AAG04600.1 - 0.051 13.4 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.13 AAG04600.1 - 0.084 12.7 0.0 0.64 9.9 0.1 2.0 2 0 0 2 2 2 0 Serine hydrolase DUF2920 PF11144.8 AAG04600.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) MFS_1 PF07690.16 AAG04601.1 - 5.4e-33 114.4 41.5 3.4e-31 108.5 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAG04601.1 - 1.7e-08 33.7 11.6 0.00015 20.8 0.0 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 AAG04601.1 - 2.2e-06 26.5 20.7 0.0015 17.2 1.4 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 AAG04601.1 - 6.2e-06 24.9 12.2 7.6e-06 24.6 1.4 2.5 2 1 1 3 3 3 3 Transmembrane secretion effector Sugar_tr PF00083.24 AAG04601.1 - 0.00042 19.3 4.5 0.00042 19.3 4.5 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 AAG04601.1 - 0.32 9.2 3.3 0.63 8.3 1.2 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TauD PF02668.16 AAG04602.1 - 6.8e-17 62.1 0.3 9.3e-17 61.7 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 AAG04602.1 - 3e-06 26.6 0.0 5.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 CsiD Asn_synthase PF00733.21 AAG04603.1 - 1.7e-45 156.2 0.4 2.2e-45 155.9 0.4 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAG04603.1 - 2.1e-14 53.5 0.0 2.2e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAG04603.1 - 2.7e-11 43.8 0.0 5.5e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 Glutamine amidotransferase domain AMP-binding PF00501.28 AAG04604.1 - 3.7e-49 167.5 0.0 2e-48 165.1 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG04604.1 - 0.023 15.7 0.0 0.045 14.7 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF4652 PF15525.6 AAG04604.1 - 0.038 13.8 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Methyltransf_25 PF13649.6 AAG04605.1 - 1.3e-13 51.5 0.0 3.1e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG04605.1 - 3.8e-12 46.7 0.0 8.3e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG04605.1 - 3.1e-10 40.1 0.0 4.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG04605.1 - 6.3e-09 35.8 0.0 9.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG04605.1 - 4e-08 33.9 0.0 8.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AAG04605.1 - 5.9e-06 26.0 0.0 8.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 AAG04605.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AdoMet_MTase PF07757.13 AAG04605.1 - 0.13 12.6 0.0 11 6.4 0.0 2.3 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 AAG04605.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB HMGL-like PF00682.19 AAG04606.1 - 6.6e-59 199.6 1.6 8.1e-59 199.3 1.6 1.1 1 0 0 1 1 1 1 HMGL-like DUF442 PF04273.13 AAG04606.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) PdxJ PF03740.13 AAG04606.1 - 0.069 12.3 0.2 0.97 8.5 0.0 2.2 1 1 1 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ Radical_SAM PF04055.21 AAG04606.1 - 0.11 12.9 0.1 0.3 11.4 0.1 1.9 1 1 0 1 1 1 0 Radical SAM superfamily HEPN_SAV2148 PF18725.1 AAG04606.1 - 0.5 9.7 6.4 5.5 6.3 0.7 2.3 1 1 1 2 2 2 0 SAV2148-like HEPN PhyH PF05721.13 AAG04607.1 - 6.9e-31 108.1 0.2 1e-30 107.6 0.2 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 AAG04607.1 - 0.006 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Sulphotransf PF09037.10 AAG04607.1 - 0.065 12.8 0.3 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 Stf0 sulphotransferase Cupin_2 PF07883.11 AAG04607.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Thioesterase PF00975.20 AAG04608.1 - 4.7e-09 36.7 0.1 8.3e-09 35.9 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AAG04608.1 - 1.4e-08 35.7 4.2 1.6e-08 35.4 4.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG04608.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Condensation PF00668.20 AAG04609.1 - 0.0089 14.7 0.0 0.045 12.4 0.0 1.9 1 1 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 AAG04610.1 - 2.4e-62 210.9 0.0 6.6e-62 209.5 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 AAG04610.1 - 5.6e-06 26.6 0.3 2.3e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAG04610.1 - 0.019 15.9 0.0 0.089 13.8 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain MltA PF03562.17 AAG04611.1 - 5.6e-76 255.2 0.0 7e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 MltA specific insert domain 3D PF06725.11 AAG04611.1 - 6.6e-24 83.9 0.0 1.3e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 3D domain AsmA_2 PF13502.6 AAG04611.1 - 0.056 13.0 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region LysR_substrate PF03466.20 AAG04612.1 - 1.8e-34 118.9 13.2 3e-34 118.2 13.2 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04612.1 - 1.6e-14 53.6 0.0 4e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AAG04612.1 - 0.0045 16.8 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 AAG04612.1 - 0.0077 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Flavodoxin_2 PF02525.17 AAG04613.1 - 4.3e-57 193.0 0.0 5.2e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAG04613.1 - 1.5e-11 44.3 0.0 3.9e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AAG04614.1 - 9.2e-44 149.5 0.0 1.1e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAG04614.1 - 1.7e-15 57.1 0.0 3.6e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase TetR_N PF00440.23 AAG04615.1 - 8.2e-13 47.9 0.5 2.1e-12 46.6 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 AAG04615.1 - 0.025 14.4 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain APH PF01636.23 AAG04616.1 - 5.5e-26 92.0 6.9 8.3e-26 91.4 6.9 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MCPVI PF02993.14 AAG04617.1 - 0.0011 18.9 2.9 0.0013 18.6 2.9 1.1 1 0 0 1 1 1 1 Minor capsid protein VI HTH_18 PF12833.7 AAG04618.1 - 1.5e-19 70.0 0.2 2.7e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04618.1 - 2.7e-08 33.7 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG04618.1 - 0.00067 19.6 0.1 0.0021 17.9 0.1 1.9 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG04618.1 - 0.002 17.8 0.2 0.0032 17.1 0.2 1.3 1 0 0 1 1 1 1 Cupin domain HTH_23 PF13384.6 AAG04618.1 - 0.08 12.8 3.9 5 7.1 0.2 2.6 2 1 0 2 2 2 0 Homeodomain-like domain DUF1656 PF07869.12 AAG04619.1 - 3.2e-11 43.1 9.7 3.9e-11 42.8 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) Biotin_lipoyl_2 PF13533.6 AAG04620.1 - 1e-19 70.1 0.1 2e-14 53.1 0.0 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG04620.1 - 8e-17 61.2 0.1 1.4e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG04620.1 - 1.2e-11 45.2 0.1 1.1e-08 35.8 0.0 2.6 2 1 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AAG04620.1 - 9.6e-07 28.6 0.0 5.6e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG04620.1 - 0.0019 18.0 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme OEP PF02321.18 AAG04620.1 - 5 6.9 12.5 60 3.4 12.3 2.4 2 1 0 2 2 2 0 Outer membrane efflux protein FUSC PF04632.12 AAG04621.1 - 5.4e-142 474.6 62.0 6.1e-142 474.4 62.0 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAG04621.1 - 1.3e-07 31.8 17.1 1.3e-07 31.8 17.1 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AAG04621.1 - 0.0016 18.6 9.7 0.0038 17.4 8.9 2.1 1 1 0 1 1 1 1 Aromatic acid exporter family member 1 DUF2790 PF10976.8 AAG04622.1 - 2.9e-25 88.1 0.0 3.4e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2790) Thioredoxin_9 PF14595.6 AAG04623.1 - 3.3e-24 85.1 0.0 4e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 AAG04623.1 - 0.14 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like HTH_18 PF12833.7 AAG04624.1 - 1.7e-25 89.0 1.1 3.8e-25 88.0 1.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04624.1 - 3.3e-19 68.5 0.0 1.4e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG04624.1 - 4.6e-10 39.5 0.2 1.3e-09 38.1 0.1 1.9 1 1 1 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG04624.1 - 1.8e-08 34.0 0.3 3.1e-08 33.2 0.3 1.3 1 0 0 1 1 1 1 Cupin domain HTH_23 PF13384.6 AAG04624.1 - 8.8e-06 25.4 0.4 0.00017 21.3 0.0 2.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_8 PF02954.19 AAG04624.1 - 0.00013 21.7 2.4 0.00015 21.5 0.1 2.3 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family HTH_1 PF00126.27 AAG04624.1 - 0.0023 17.8 0.8 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AAG04624.1 - 0.0023 18.0 0.8 0.2 11.8 0.1 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 AAG04624.1 - 0.012 16.0 10.1 0.016 15.6 6.2 2.8 2 1 1 3 3 2 0 Helix-turn-helix domain HTH_38 PF13936.6 AAG04624.1 - 0.018 14.8 0.1 0.76 9.6 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAG04624.1 - 0.018 14.4 0.1 0.1 12.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 AAG04624.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix MerR PF00376.23 AAG04624.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein MarR_2 PF12802.7 AAG04624.1 - 0.05 13.5 1.1 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 MarR family HTH_29 PF13551.6 AAG04624.1 - 0.062 13.3 0.2 0.64 10.1 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn helix AbiEi_4 PF13338.6 AAG04624.1 - 0.47 10.7 2.7 7.5 6.8 0.1 3.1 3 1 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin MFS_1 PF07690.16 AAG04625.1 - 3.5e-43 147.9 41.4 5.2e-43 147.3 41.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 AAG04625.1 - 2.4e-06 26.2 15.8 4.3e-06 25.5 15.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 AAG04625.1 - 1.6e-05 23.5 11.8 1.6e-05 23.5 11.8 2.5 1 1 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 AAG04625.1 - 0.0035 16.3 5.7 0.0035 16.3 5.7 2.1 2 0 0 2 2 2 1 MFS_1 like family SatD PF16264.5 AAG04625.1 - 0.22 11.1 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 SatD family (SatD) HlyD_3 PF13437.6 AAG04626.1 - 1.6e-15 57.7 0.7 7e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAG04626.1 - 3.6e-15 55.8 9.3 4.1e-12 45.8 9.3 2.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG04626.1 - 5.6e-11 42.1 1.3 5.6e-11 42.1 1.3 3.4 4 0 0 4 4 4 1 Biotin-lipoyl like HlyD PF00529.20 AAG04626.1 - 1.7e-05 24.6 0.2 2.2e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG04626.1 - 0.00045 20.0 0.0 0.0028 17.4 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Fez1 PF06818.15 AAG04626.1 - 8.7 6.7 18.8 21 5.5 18.7 1.6 1 1 0 1 1 1 0 Fez1 DUF3584 PF12128.8 AAG04626.1 - 9.1 3.6 27.7 14 3.0 27.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OEP PF02321.18 AAG04627.1 - 1.5e-37 129.3 32.2 4.6e-22 78.7 12.0 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein Hydrolase_4 PF12146.8 AAG04628.1 - 1.2e-12 47.7 0.7 1.1e-09 37.9 0.4 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAG04628.1 - 5.1e-11 43.6 18.7 6.9e-11 43.2 18.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG04628.1 - 2.1e-07 30.8 0.1 7.5e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAG04628.1 - 0.014 14.8 0.3 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family ECH_1 PF00378.20 AAG04629.1 - 5e-34 117.7 0.0 5.7e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG04629.1 - 4.7e-14 52.6 0.3 1.4e-10 41.2 0.1 2.6 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MliC PF09864.9 AAG04629.1 - 0.09 12.7 0.0 0.64 10.0 0.0 2.2 1 1 1 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme TetR_N PF00440.23 AAG04630.1 - 4.2e-13 48.9 0.0 1.3e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 AAG04630.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Peptidase_S8 PF00082.22 AAG04631.1 - 2.7e-21 76.1 0.0 3.8e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Subtilase family PAS_4 PF08448.10 AAG04632.1 - 4.5e-22 78.4 1.1 1.5e-11 44.5 0.1 3.0 2 1 0 2 2 2 2 PAS fold Response_reg PF00072.24 AAG04632.1 - 3.5e-17 62.6 0.0 7.8e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAG04632.1 - 1.8e-16 60.7 0.1 8.5e-16 58.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAG04632.1 - 2e-11 43.9 0.0 3.9e-08 33.3 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAG04632.1 - 2.3e-10 40.6 0.0 2.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 AAG04632.1 - 8e-09 35.4 0.7 8e-09 35.4 0.7 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 AAG04632.1 - 1.1e-08 35.3 0.0 2.7e-06 27.6 0.0 2.7 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAG04632.1 - 2.1e-07 30.8 0.0 1.3e-06 28.3 0.0 2.4 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.6 AAG04632.1 - 1.4e-05 25.4 2.5 4.2e-05 23.9 1.3 2.3 2 0 0 2 2 2 1 GAF domain FleQ PF06490.11 AAG04632.1 - 0.00063 20.1 0.3 0.0035 17.7 0.0 2.2 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ PAS_7 PF12860.7 AAG04632.1 - 0.0057 16.8 0.0 0.088 13.0 0.0 2.8 2 1 0 2 2 2 1 PAS fold PAS_10 PF13596.6 AAG04632.1 - 0.028 15.0 0.0 14 6.3 0.0 2.8 2 1 0 2 2 2 0 PAS domain DAPG_hydrolase PF18089.1 AAG04632.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain QslA_E PF18226.1 AAG04633.1 - 2e-32 110.9 0.3 2.6e-32 110.6 0.3 1.1 1 0 0 1 1 1 1 LasR-specific antiactivator QslA chain E Baculo_PEP_C PF04513.12 AAG04634.1 - 0.075 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 AAG04635.1 - 1.2e-28 100.3 0.0 1.9e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAG04635.1 - 1.4e-12 47.9 3.2 2.2e-12 47.2 3.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAG04635.1 - 1.6e-06 27.7 0.0 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAG04635.1 - 0.00023 20.8 0.1 0.64 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 AAG04635.1 - 0.00029 20.8 0.0 0.63 9.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG04635.1 - 0.0012 19.3 2.0 0.0016 18.8 0.5 2.1 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AAG04635.1 - 0.014 14.8 0.1 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAG04635.1 - 0.091 12.9 0.1 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAG04635.1 - 0.095 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 AAG04635.1 - 0.12 12.8 0.0 0.71 10.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HlyD PF00529.20 AAG04636.1 - 8.4e-21 73.6 0.1 2.1e-20 72.4 0.0 1.6 2 0 0 2 2 2 1 HlyD membrane-fusion protein of T1SS HlyD_3 PF13437.6 AAG04636.1 - 3.5e-16 59.8 0.1 2.5e-11 44.2 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG04636.1 - 1.3e-09 37.8 1.0 8.4e-07 28.7 0.0 3.5 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG04636.1 - 1.4e-09 37.5 1.5 5.4e-05 22.5 0.1 2.7 2 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AAG04636.1 - 3.7e-06 26.7 0.1 0.0048 16.7 0.0 3.0 3 0 0 3 3 3 2 Biotin-requiring enzyme MscS_porin PF12795.7 AAG04636.1 - 0.0031 17.1 9.9 0.0031 17.1 9.9 2.5 1 1 0 2 2 2 1 Mechanosensitive ion channel porin domain Spc7 PF08317.11 AAG04636.1 - 0.017 14.0 8.0 0.026 13.4 8.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HR1 PF02185.16 AAG04636.1 - 0.039 14.1 14.3 0.73 10.0 2.4 3.7 1 1 1 3 3 3 0 Hr1 repeat DUF3592 PF12158.8 AAG04636.1 - 0.058 13.5 0.1 1.5 8.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) Laminin_II PF06009.12 AAG04636.1 - 0.38 10.8 2.9 1.5 8.8 1.0 2.3 1 1 1 2 2 2 0 Laminin Domain II Muted PF14942.6 AAG04636.1 - 1.1 9.6 9.1 8.8 6.7 2.6 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4407 PF14362.6 AAG04636.1 - 2.4 7.4 17.9 3.2 7.0 13.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4349 PF14257.6 AAG04636.1 - 3 7.3 10.1 9 5.7 0.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) Macoilin PF09726.9 AAG04636.1 - 5.2 5.5 10.5 6.7 5.1 10.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF4200 PF13863.6 AAG04636.1 - 5.2 7.5 9.5 9.4 6.7 6.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 AAG04636.1 - 7.4 5.6 13.2 12 4.9 3.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 OEP PF02321.18 AAG04637.1 - 2.3e-57 193.9 32.2 2.7e-32 112.1 7.1 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein Corona_NSP4_C PF16348.5 AAG04637.1 - 0.028 15.2 0.5 0.1 13.4 0.1 2.1 2 0 0 2 2 2 0 Coronavirus nonstructural protein 4 C-terminus Peptidase_M10_C PF08548.11 AAG04638.1 - 3.5e-82 275.0 7.2 3.5e-82 275.0 7.2 2.2 2 1 0 2 2 2 1 Peptidase M10 serralysin C terminal HemolysinCabind PF00353.19 AAG04638.1 - 1.7e-15 56.6 26.8 8.5e-10 38.4 9.3 4.2 3 1 1 4 4 4 2 RTX calcium-binding nonapeptide repeat (4 copies) Peptidase_M10 PF00413.24 AAG04638.1 - 7.8e-06 25.8 1.1 0.00035 20.5 0.4 3.2 2 1 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 AAG04638.1 - 9e-06 25.5 0.1 1.8e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AAG04638.1 - 6.2e-05 23.2 0.1 0.00014 22.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 AAG04638.1 - 0.00012 22.6 0.1 0.00028 21.4 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 AAG04638.1 - 0.00052 20.0 0.1 0.00094 19.1 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.6 AAG04638.1 - 0.00088 19.2 0.2 0.0019 18.2 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 AAG04638.1 - 0.011 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 AAG04638.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 AAG04638.1 - 0.1 12.6 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M54 Astacin PF01400.24 AAG04638.1 - 0.1 12.2 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Inh PF02974.14 AAG04639.1 - 6.2e-22 77.5 0.0 7.2e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Protease inhibitor Inh MCPsignal PF00015.21 AAG04640.1 - 1e-42 145.9 35.1 4.7e-42 143.7 20.9 3.1 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAG04640.1 - 4.6e-21 75.2 0.0 4.6e-21 75.2 0.0 3.2 3 1 2 5 5 5 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAG04640.1 - 1.5e-06 28.4 12.5 2.1e-05 24.8 0.1 4.7 3 1 1 4 4 4 2 HAMP domain Sec34 PF04136.15 AAG04640.1 - 1.6 8.6 4.3 14 5.6 0.1 3.2 3 0 0 3 3 3 0 Sec34-like family Ldh_2 PF02615.14 AAG04641.1 - 4.1e-101 338.5 0.2 4.6e-101 338.3 0.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Aldedh PF00171.22 AAG04642.1 - 2.7e-47 161.3 0.0 4.4e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mating_N PF12731.7 AAG04642.1 - 0.084 13.0 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Mating-type protein beta 1 LAL_C2 PF18603.1 AAG04642.1 - 0.24 11.6 4.5 4.2 7.6 0.0 3.6 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 DHDPS PF00701.22 AAG04643.1 - 4.4e-59 199.6 0.0 5.1e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CbiX PF01903.17 AAG04643.1 - 0.17 12.2 0.1 0.51 10.7 0.0 1.8 2 0 0 2 2 2 0 CbiX Pro_racemase PF05544.11 AAG04644.1 - 5.8e-140 466.0 0.0 6.6e-140 465.8 0.0 1.0 1 0 0 1 1 1 1 Proline racemase ABC_tran PF00005.27 AAG04645.1 - 6.7e-34 117.4 0.0 8.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG04645.1 - 1.6e-06 28.2 0.3 0.019 14.8 0.3 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG04645.1 - 1.2e-05 24.8 0.2 5.1e-05 22.8 0.2 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG04645.1 - 0.00021 21.0 0.2 0.00044 19.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAG04645.1 - 0.0026 16.7 0.4 0.49 9.1 0.2 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 AAG04645.1 - 0.015 15.8 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG04645.1 - 0.017 15.4 0.5 0.29 11.4 0.5 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AAG04645.1 - 0.037 13.9 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF416 PF04222.12 AAG04645.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) AAA_19 PF13245.6 AAG04645.1 - 0.15 12.3 0.3 0.24 11.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG04645.1 - 0.16 12.2 1.1 1.1 9.5 1.1 2.1 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAG04646.1 - 1.3e-16 60.9 11.5 1.3e-16 60.9 11.5 1.6 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG04647.1 - 1.3e-12 47.8 17.3 1.6e-12 47.6 16.8 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF521 PF04412.13 AAG04648.1 - 1.8e-147 491.3 0.0 2.1e-147 491.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 AAG04648.1 - 1.3e-29 101.8 0.0 2.6e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase X swivel domain Aconitase PF00330.20 AAG04648.1 - 0.0048 15.9 0.0 0.0072 15.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) SBP_bac_3 PF00497.20 AAG04649.1 - 3.2e-48 164.1 0.0 3.9e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAG04649.1 - 2.8e-06 27.4 0.0 2.3e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAG04649.1 - 0.0028 17.3 0.2 0.0074 15.9 0.3 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Lig_chan-Glu_bd PF10613.9 AAG04649.1 - 0.04 14.1 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site Albumin_I PF08027.11 AAG04649.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Albumin I chain b HTH_18 PF12833.7 AAG04650.1 - 8e-24 83.7 0.2 1.4e-23 82.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04650.1 - 1.6e-20 72.7 0.0 7.2e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family PAS_4 PF08448.10 AAG04650.1 - 1.6e-19 70.1 0.1 3.7e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG04650.1 - 5.8e-07 29.7 0.0 1.8e-06 28.2 0.0 1.7 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 AAG04650.1 - 0.022 14.7 0.0 0.069 13.2 0.0 1.9 2 1 0 2 2 2 0 PAS fold PAS_8 PF13188.7 AAG04650.1 - 0.035 14.1 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain MFS_1 PF07690.16 AAG04651.1 - 4.5e-46 157.4 55.3 4.4e-44 150.9 55.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG04651.1 - 2.3e-09 36.7 8.8 2.3e-09 36.7 8.8 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 AAG04651.1 - 0.0017 17.3 9.7 0.0017 17.3 9.7 2.3 2 1 0 2 2 2 1 MFS_1 like family TRI12 PF06609.13 AAG04651.1 - 0.0029 16.1 2.3 0.0051 15.3 2.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 AAG04651.1 - 0.67 8.2 7.5 0.3 9.3 0.2 2.5 1 1 2 3 3 2 0 Organic Anion Transporter Polypeptide (OATP) family MLTR_LBD PF17765.1 AAG04652.1 - 1.5e-35 122.8 1.2 2.1e-35 122.3 1.2 1.2 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 AAG04652.1 - 8.5e-15 54.9 10.9 1.3e-14 54.3 9.2 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 AAG04652.1 - 0.04 13.8 0.3 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LysR_substrate PF03466.20 AAG04653.1 - 5.3e-22 78.2 7.1 8.4e-22 77.6 7.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04653.1 - 1.1e-17 63.8 0.8 2.2e-17 62.8 0.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAG04653.1 - 0.012 15.1 0.1 0.041 13.5 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAG04653.1 - 0.19 11.6 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family EamA PF00892.20 AAG04654.1 - 1.6e-24 86.6 29.8 6e-14 52.4 9.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family Pyr_redox_2 PF07992.14 AAG04655.1 - 6.4e-20 71.6 0.0 1.3e-19 70.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG04655.1 - 4.6e-09 36.1 0.5 4.6e-09 36.1 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG04655.1 - 2.6e-07 30.1 0.1 2.6e-07 30.1 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 AAG04655.1 - 4.7e-07 29.2 2.6 0.00035 19.8 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAG04655.1 - 8.2e-06 26.0 0.6 2.9e-05 24.2 0.5 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAG04655.1 - 1.5e-05 23.9 0.2 2.6e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 AAG04655.1 - 2.3e-05 24.4 0.2 0.0015 18.5 0.2 2.4 1 1 1 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 AAG04655.1 - 3.6e-05 23.1 0.1 6.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 AAG04655.1 - 0.0013 18.4 6.8 0.002 17.8 4.9 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase XdhC_C PF13478.6 AAG04655.1 - 0.0017 18.8 0.0 0.3 11.6 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain FAD_binding_3 PF01494.19 AAG04655.1 - 0.0049 16.1 0.2 0.0076 15.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAG04655.1 - 0.01 15.1 0.9 0.01 15.1 0.9 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAG04655.1 - 0.023 14.0 0.1 0.023 14.0 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 AAG04655.1 - 0.026 13.6 0.8 0.052 12.6 0.8 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 AAG04655.1 - 0.17 12.3 0.0 8.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 AAG04656.1 - 1.1e-56 193.0 8.3 1.2e-56 192.8 8.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG04656.1 - 1.3e-08 34.9 0.2 1.5e-07 31.5 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAG04656.1 - 2.9e-08 33.2 2.3 3.7e-08 32.9 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AAG04656.1 - 0.00033 20.0 0.2 0.00051 19.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 AAG04656.1 - 0.00038 19.8 0.6 0.00092 18.5 0.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG04656.1 - 0.00039 19.8 1.8 0.00058 19.2 1.8 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAG04656.1 - 0.001 18.5 0.8 0.0013 18.1 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAG04656.1 - 0.0013 18.7 0.5 0.0019 18.1 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AAG04656.1 - 0.0021 17.7 0.4 0.0037 16.9 0.4 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 AAG04656.1 - 0.0021 17.2 0.6 0.0041 16.2 0.6 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 AAG04656.1 - 0.0096 14.7 1.0 0.033 12.9 1.5 1.6 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 AAG04656.1 - 0.019 14.3 1.1 0.019 14.3 1.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AAG04656.1 - 0.02 15.4 0.5 0.038 14.5 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 AAG04656.1 - 0.022 14.7 0.2 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_9 PF13454.6 AAG04656.1 - 0.023 14.7 0.8 12 5.9 0.0 2.8 2 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 AAG04656.1 - 0.026 13.8 0.3 0.036 13.3 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG04656.1 - 0.03 13.9 0.1 0.043 13.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 AAG04656.1 - 0.03 13.7 0.4 0.049 13.0 0.4 1.3 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 AAG04656.1 - 0.044 12.8 0.3 0.085 11.9 0.3 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Epimerase PF01370.21 AAG04656.1 - 0.045 13.2 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 AAG04656.1 - 0.054 13.8 0.3 0.092 13.0 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 AAG04656.1 - 0.099 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 AAG04656.1 - 0.15 12.3 0.9 0.28 11.4 0.9 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain XdhC_C PF13478.6 AAG04656.1 - 0.25 11.9 2.0 0.23 12.0 0.5 1.8 2 1 0 2 2 1 0 XdhC Rossmann domain Pro_racemase PF05544.11 AAG04657.1 - 2.3e-111 372.0 0.0 2.6e-111 371.8 0.0 1.0 1 0 0 1 1 1 1 Proline racemase DAP_epimerase PF01678.19 AAG04657.1 - 0.0019 18.4 0.1 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Diaminopimelate epimerase PhzC-PhzF PF02567.16 AAG04657.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein FCD PF07729.12 AAG04658.1 - 3.9e-29 101.6 5.0 6.5e-29 100.9 5.0 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAG04658.1 - 8.5e-17 60.6 0.9 7e-16 57.6 0.1 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AAG04658.1 - 2.6e-05 23.7 0.0 6.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 AAG04658.1 - 3.2e-05 24.0 0.0 0.00031 20.9 0.0 2.3 3 0 0 3 3 2 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 AAG04658.1 - 0.0013 18.6 0.1 0.0039 17.0 0.0 1.9 2 0 0 2 2 1 1 MarR family MarR PF01047.22 AAG04658.1 - 0.002 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAG04658.1 - 0.0026 17.7 0.0 0.0063 16.5 0.0 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_27 PF13463.6 AAG04658.1 - 0.0045 17.5 0.0 0.009 16.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_10 PF04967.12 AAG04658.1 - 0.005 16.6 0.0 0.022 14.5 0.0 2.1 1 1 1 2 2 2 1 HTH DNA binding domain HTH_11 PF08279.12 AAG04658.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 HTH domain FaeA PF04703.12 AAG04658.1 - 0.028 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 FaeA-like protein HTH_DeoR PF08220.12 AAG04658.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TrmB PF01978.19 AAG04658.1 - 0.039 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAG04658.1 - 0.046 14.1 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_28 PF13518.6 AAG04658.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AAG04658.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix TFIIE_alpha PF02002.17 AAG04658.1 - 0.13 12.1 0.1 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit Phage_rep_O PF04492.13 AAG04658.1 - 0.14 12.7 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage replication protein O HTH_36 PF13730.6 AAG04658.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FUSC PF04632.12 AAG04659.1 - 1.5e-188 628.4 50.9 1.9e-188 628.1 50.9 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAG04659.1 - 3.3e-13 49.9 13.4 3.3e-13 49.9 13.4 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 AAG04659.1 - 2.2e-05 23.5 4.1 3.7e-05 22.8 4.1 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter ArAE_1 PF06081.11 AAG04659.1 - 0.0018 18.4 11.8 0.059 13.5 6.0 2.5 2 0 0 2 2 2 2 Aromatic acid exporter family member 1 Erythro_esteras PF05139.14 AAG04659.1 - 0.0063 16.4 1.5 0.12 12.2 0.3 2.4 2 1 0 2 2 2 1 Erythromycin esterase HisKA PF00512.25 AAG04659.1 - 0.19 11.8 1.8 6.4 6.9 0.1 2.7 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TonB_dep_Rec PF00593.24 AAG04660.1 - 5.9e-48 164.9 40.2 7.6e-48 164.5 40.2 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG04660.1 - 4.5e-30 104.4 1.4 9e-30 103.4 0.4 2.1 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG04660.1 - 0.00031 19.8 0.0 0.001 18.2 0.0 1.8 2 1 0 2 2 2 1 Outer membrane protein beta-barrel family CobA_CobO_BtuR PF02572.15 AAG04661.1 - 6.7e-59 199.0 0.4 6.7e-59 199.0 0.4 1.3 2 0 0 2 2 2 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Co_AT_N PF12557.8 AAG04661.1 - 7.2e-10 38.5 5.1 1.6e-09 37.5 5.1 1.6 1 0 0 1 1 1 1 Cob(I)alamin adenosyltransferase N terminal GATase_3 PF07685.14 AAG04662.1 - 6.1e-31 107.5 0.0 8.1e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AAG04662.1 - 3.3e-13 49.8 0.0 6.3e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AAG04662.1 - 1.1e-07 31.9 0.0 0.0078 16.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain MobB PF03205.14 AAG04662.1 - 0.12 12.2 0.0 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SNO PF01174.19 AAG04662.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family AAA_30 PF13604.6 AAG04662.1 - 0.15 11.8 0.4 0.36 10.5 0.4 1.7 1 1 0 1 1 1 0 AAA domain MdcE PF06833.11 AAG04662.1 - 0.51 9.8 4.1 2.2 7.7 0.9 2.9 3 1 1 4 4 4 0 Malonate decarboxylase gamma subunit (MdcE) Nitroreductase PF00881.24 AAG04663.1 - 2.2e-26 92.9 0.0 2.7e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAG04663.1 - 0.21 11.1 0.1 2 7.9 0.0 2.2 2 1 0 2 2 2 0 Putative TM nitroreductase CobD_Cbib PF03186.13 AAG04664.1 - 3.1e-95 318.5 1.3 3.1e-95 318.5 1.3 1.5 2 0 0 2 2 2 1 CobD/Cbib protein AmpE PF17113.5 AAG04664.1 - 9.6e-07 28.4 0.5 1.8e-06 27.5 0.5 1.4 1 0 0 1 1 1 1 Regulatory signalling modulator protein AmpE Aminotran_1_2 PF00155.21 AAG04665.1 - 9e-31 107.3 0.0 1.2e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ala_racemase_N PF01168.20 AAG04665.1 - 0.049 13.3 0.1 0.095 12.3 0.1 1.5 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain GATase_3 PF07685.14 AAG04666.1 - 5.9e-59 199.0 0.0 1.2e-58 198.0 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AAG04666.1 - 1.4e-23 83.3 0.0 2.6e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AAG04666.1 - 2.4e-21 76.5 0.0 5.8e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG04666.1 - 0.039 14.4 0.4 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.14 AAG04666.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.16 AAG04667.1 - 3.6e-59 199.1 0.0 4.1e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_16 PF13191.6 AAG04667.1 - 0.01 16.2 1.6 0.023 15.1 1.6 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 AAG04667.1 - 0.011 16.0 0.1 0.028 14.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAG04667.1 - 0.13 12.6 0.1 0.36 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain DBI_PRT PF02277.17 AAG04668.1 - 4.1e-130 433.8 14.7 4.5e-130 433.7 14.7 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase MAAL_C PF07476.11 AAG04668.1 - 0.22 10.6 5.0 0.12 11.5 0.6 2.4 2 1 1 3 3 3 0 Methylaspartate ammonia-lyase C-terminus His_Phos_1 PF00300.22 AAG04669.1 - 6.7e-43 146.6 3.2 7.5e-43 146.5 3.2 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CobS PF02654.15 AAG04670.1 - 6.7e-52 176.7 17.5 7.6e-52 176.5 17.5 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase Phage_holin_5_1 PF06946.11 AAG04670.1 - 0.71 10.3 3.4 0.38 11.1 0.4 2.1 2 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 MFS_1 PF07690.16 AAG04671.1 - 4.6e-48 163.9 44.7 4.6e-48 163.9 44.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 AAG04671.1 - 0.62 9.7 12.6 0.33 10.6 0.2 3.3 3 2 0 3 3 3 0 Cation transporting ATPase, C-terminus OATP PF03137.20 AAG04671.1 - 9.5 4.4 7.7 0.27 9.5 0.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TetR_C_28 PF17937.1 AAG04672.1 - 1.3e-15 57.6 4.3 1.3e-15 57.6 4.3 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAG04672.1 - 7.2e-11 41.7 0.2 1.4e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Acyl-CoA_dh_C PF12806.7 AAG04673.1 - 1.7e-22 79.9 1.8 3.6e-22 78.8 1.8 1.6 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 AAG04673.1 - 1.1e-19 70.4 0.0 2.5e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 AAG04673.1 - 4.1e-19 69.3 6.2 6.5e-19 68.6 2.7 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG04673.1 - 1.2e-15 58.1 0.1 2.8e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 AAG04673.1 - 2.9e-08 33.6 0.3 7.3e-08 32.3 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 AAG04673.1 - 0.01 16.1 0.8 0.023 15.0 0.2 2.1 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain MarR_2 PF12802.7 AAG04674.1 - 1e-10 41.3 1.2 1e-10 41.3 1.2 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAG04674.1 - 1.7e-10 41.2 0.3 3.2e-09 37.1 0.2 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.22 AAG04674.1 - 1.6e-09 37.5 0.1 3e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAG04674.1 - 8.2e-07 28.7 1.2 8.2e-07 28.7 1.2 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AAG04674.1 - 1.1e-06 28.6 2.3 1.1e-06 28.6 2.3 2.3 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_5 PF01022.20 AAG04674.1 - 6.2e-05 22.8 0.5 0.00065 19.5 0.4 2.2 1 1 1 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAG04674.1 - 0.00012 21.5 0.5 0.00024 20.6 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 AAG04674.1 - 0.00084 18.9 0.1 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAG04674.1 - 0.0017 18.3 0.7 0.0017 18.3 0.7 2.0 2 2 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AAG04674.1 - 0.003 17.7 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_36 PF13730.6 AAG04674.1 - 0.0045 16.9 0.0 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AAG04674.1 - 0.01 15.8 0.3 0.027 14.5 0.3 1.8 1 1 0 1 1 1 0 Winged helix-turn helix LexA_DNA_bind PF01726.16 AAG04674.1 - 0.029 14.2 0.1 0.078 12.8 0.1 1.8 1 1 0 1 1 1 0 LexA DNA binding domain TrmB PF01978.19 AAG04674.1 - 0.046 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AAG04674.1 - 0.049 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 HTH domain MFS_1 PF07690.16 AAG04675.1 - 6.7e-32 110.8 59.4 1.8e-28 99.5 47.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG04675.1 - 2.3e-06 27.1 17.8 2.3e-06 27.1 17.8 2.0 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AAG04675.1 - 1.1 7.4 10.0 0.79 7.9 0.2 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pam17 PF08566.10 AAG04675.1 - 9.1 6.1 6.0 2.1 8.2 1.2 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 GSHPx PF00255.19 AAG04676.1 - 1.3e-22 79.4 0.0 1.8e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AAG04676.1 - 7.2e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG04676.1 - 0.006 16.3 0.0 0.025 14.3 0.0 1.9 1 1 0 1 1 1 1 Redoxin Toluene_X PF03349.16 AAG04677.1 - 4e-135 450.7 11.0 4.6e-135 450.5 11.0 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) DUF2490 PF10677.9 AAG04677.1 - 0.00019 21.5 3.1 2.6 7.9 0.3 3.7 2 1 0 3 3 3 3 Protein of unknown function (DUF2490) OmpA_membrane PF01389.17 AAG04677.1 - 0.00027 20.7 0.9 0.052 13.3 0.1 3.2 2 1 1 3 3 3 1 OmpA-like transmembrane domain OMP_b-brl_2 PF13568.6 AAG04677.1 - 0.015 15.4 3.4 2.4 8.2 0.1 4.1 3 2 3 6 6 6 0 Outer membrane protein beta-barrel domain YadA_anchor PF03895.15 AAG04677.1 - 0.4 10.8 3.9 3.7 7.7 0.0 4.2 3 2 1 4 4 4 0 YadA-like membrane anchor domain VasL PF12486.8 AAG04678.1 - 0.088 12.7 0.3 1.9 8.3 0.1 2.0 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL TetR_N PF00440.23 AAG04679.1 - 1.8e-18 66.0 0.3 4.3e-18 64.8 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Abhydrolase_6 PF12697.7 AAG04680.1 - 2.9e-10 41.1 13.4 4e-10 40.7 13.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG04680.1 - 1.2e-05 24.7 0.1 1.5e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG04680.1 - 0.0011 18.7 0.4 0.0035 17.0 0.3 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Rhodanese PF00581.20 AAG04681.1 - 7.2e-30 103.7 0.0 9.3e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Str_synth PF03088.16 AAG04682.1 - 1.1e-31 108.8 0.0 2.4e-30 104.5 0.0 2.4 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 AAG04682.1 - 2.1e-23 83.2 0.0 1.9e-21 76.8 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AAG04682.1 - 8.4e-06 25.6 0.1 3.8 7.7 0.0 4.7 5 0 0 5 5 5 2 NHL repeat PQQ_3 PF13570.6 AAG04682.1 - 0.0059 17.1 1.4 0.18 12.4 0.2 3.1 3 0 0 3 3 3 1 PQQ-like domain RHS_repeat PF05593.14 AAG04682.1 - 0.016 15.7 3.8 14 6.3 0.4 4.7 3 1 1 4 4 4 0 RHS Repeat PQQ PF01011.21 AAG04682.1 - 0.021 14.7 0.0 0.15 12.0 0.0 2.4 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.6 AAG04682.1 - 0.049 13.2 0.0 0.21 11.2 0.0 2.0 2 1 0 2 2 2 0 PQQ-like domain DNA_pol_A_exo1 PF01612.20 AAG04683.1 - 1.5e-38 132.3 0.0 2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 AAG04683.1 - 7.7e-20 70.7 8.6 3.2e-17 62.2 0.7 2.8 3 0 0 3 3 3 2 HRDC domain Ribosomal_L27_C PF18471.1 AAG04683.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain YcgL PF05166.13 AAG04684.1 - 1.9e-32 111.4 0.1 7.1e-32 109.6 0.1 1.7 2 0 0 2 2 2 1 YcgL domain AHJR-like PF18743.1 AAG04684.1 - 0.054 13.1 0.1 0.075 12.6 0.1 1.2 1 0 0 1 1 1 0 REase_AHJR-like DAHP_snth_FXD PF18152.1 AAG04684.1 - 0.088 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain 2-Hacid_dh_C PF02826.19 AAG04685.1 - 2e-42 144.6 0.0 2.4e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AAG04685.1 - 0.00016 21.3 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 AAG04685.1 - 0.00035 21.0 0.0 0.00096 19.6 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 AAG04685.1 - 0.00041 20.6 0.0 0.00066 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 AAG04685.1 - 0.0049 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 AAG04685.1 - 0.07 13.4 0.4 4.3 7.6 0.4 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AAG04685.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 AAG04685.1 - 0.072 12.4 0.7 0.13 11.6 0.2 1.6 2 0 0 2 2 2 0 ThiF family ApbA PF02558.16 AAG04685.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 AAG04685.1 - 0.1 13.2 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 AAG04685.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Cation_efflux PF01545.21 AAG04686.1 - 1.5e-41 142.3 8.1 1.8e-41 142.1 8.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1656 PF07869.12 AAG04686.1 - 0.48 10.5 0.1 0.48 10.5 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1656) DUF2721 PF11026.8 AAG04686.1 - 1.9 8.4 9.0 0.25 11.2 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Trns_repr_metal PF02583.17 AAG04687.1 - 4.6e-22 78.2 3.5 5.2e-22 78.0 3.5 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor CxxCxxCC PF03692.15 AAG04688.1 - 7.5e-10 39.4 6.6 1.6e-09 38.3 6.6 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Sigma70_r4_2 PF08281.12 AAG04689.1 - 3.5e-16 58.6 0.1 5.6e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG04689.1 - 4.4e-15 55.2 1.3 7.4e-15 54.5 1.3 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG04689.1 - 4.9e-11 42.0 0.0 7.9e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG04689.1 - 1.4e-09 38.1 0.4 1.6e-09 37.9 0.4 1.1 1 0 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 AAG04689.1 - 0.0016 17.9 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AAG04689.1 - 0.0019 18.0 0.0 0.015 15.1 0.0 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_31 PF13560.6 AAG04689.1 - 0.004 17.5 3.5 0.045 14.1 0.1 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 AAG04689.1 - 0.061 13.5 0.5 0.28 11.4 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_3 PF01381.22 AAG04689.1 - 0.086 12.9 0.1 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix GerE PF00196.19 AAG04689.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_40 PF14493.6 AAG04689.1 - 0.12 12.9 0.0 0.38 11.2 0.0 1.9 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.7 AAG04689.1 - 0.18 11.8 0.0 27 4.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain FecR PF04773.13 AAG04690.1 - 3.6e-19 69.2 0.7 6.2e-19 68.4 0.7 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG04690.1 - 9e-12 44.7 6.5 9e-12 44.7 6.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AAG04690.1 - 0.0006 19.8 0.0 0.0009 19.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) TonB_dep_Rec PF00593.24 AAG04691.1 - 1.3e-42 147.3 21.1 2.1e-42 146.6 21.1 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG04691.1 - 5.5e-19 68.7 0.2 1.3e-18 67.6 0.2 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG04691.1 - 4.1e-08 32.9 0.0 9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain Peptidase_M7 PF02031.16 AAG04691.1 - 0.031 14.4 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_S24 PF00717.23 AAG04692.1 - 9.9e-19 67.1 0.0 1.4e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 AAG04692.1 - 8.1e-15 54.8 0.0 1.8e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S9_N PF02897.15 AAG04693.1 - 6.7e-79 265.6 0.0 8.6e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 AAG04693.1 - 2e-69 233.3 0.0 3.2e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAG04693.1 - 0.003 16.9 0.0 0.0067 15.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 AAG04693.1 - 0.024 14.2 0.0 0.76 9.3 0.0 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 AAG04693.1 - 0.036 13.7 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase SLAC1 PF03595.17 AAG04694.1 - 0.002 17.4 0.6 0.0026 17.1 0.6 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel TMEM100 PF16311.5 AAG04694.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 HIT PF01230.23 AAG04695.1 - 2.2e-21 76.4 0.1 2.9e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AAG04695.1 - 7.6e-15 55.4 0.0 1e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 AAG04695.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 AAG04695.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain GATase_4 PF13230.6 AAG04696.1 - 6.8e-107 356.4 0.0 7.5e-107 356.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 AAG04696.1 - 6.9e-05 23.1 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF2937 PF11157.8 AAG04697.1 - 1.6e-62 210.0 0.4 1.9e-62 209.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) LysR_substrate PF03466.20 AAG04698.1 - 1.8e-38 132.0 8.6 2.6e-38 131.5 8.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04698.1 - 3.3e-23 81.4 0.9 3.3e-23 81.4 0.9 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR PF01047.22 AAG04698.1 - 0.022 14.7 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 MarR family PBP_like PF12727.7 AAG04698.1 - 0.033 13.3 0.0 0.064 12.4 0.0 1.5 2 0 0 2 2 2 0 PBP superfamily domain HTH_20 PF12840.7 AAG04698.1 - 0.04 14.0 4.3 2.5 8.2 0.0 4.0 2 1 2 4 4 4 0 Helix-turn-helix domain MarR_2 PF12802.7 AAG04698.1 - 0.23 11.4 3.6 0.27 11.2 0.1 3.0 4 0 0 4 4 4 0 MarR family Aminotran_5 PF00266.19 AAG04699.1 - 7.4e-20 71.2 0.0 1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAG04699.1 - 3.7e-06 26.3 0.0 4.9e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAG04699.1 - 0.083 12.1 0.5 0.26 10.5 0.0 1.9 2 1 1 3 3 3 0 Beta-eliminating lyase Hydrolase PF00702.26 AAG04700.1 - 4.3e-07 30.4 0.0 7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAG04700.1 - 1e-06 28.9 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG04700.1 - 0.00026 21.4 0.1 0.00048 20.6 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LysR_substrate PF03466.20 AAG04701.1 - 4.6e-45 153.6 12.4 6.6e-45 153.0 11.0 1.7 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04701.1 - 4.9e-18 64.8 0.7 1.1e-17 63.7 0.7 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG04701.1 - 0.0058 16.4 0.1 0.017 14.9 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain BTAD PF03704.17 AAG04701.1 - 0.2 12.1 9.0 1 9.8 0.3 2.5 2 1 0 2 2 2 0 Bacterial transcriptional activator domain MFS_1 PF07690.16 AAG04702.1 - 3.9e-39 134.6 51.6 3.9e-39 134.6 51.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily PgaD PF13994.6 AAG04702.1 - 0.36 10.9 1.9 0.39 10.8 0.6 1.7 1 1 0 1 1 1 0 PgaD-like protein DUF2070 PF09843.9 AAG04702.1 - 5.6 5.1 9.3 9.9 4.3 9.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4440 PF14534.6 AAG04703.1 - 1.6e-06 28.4 0.2 1.9e-06 28.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AAG04703.1 - 0.0042 17.7 0.4 0.0055 17.3 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain TetR_N PF00440.23 AAG04704.1 - 6e-17 61.2 0.7 9.8e-17 60.5 0.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AAG04704.1 - 4.8e-06 26.8 0.5 0.00011 22.5 0.0 2.5 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 AAG04704.1 - 0.035 14.8 1.5 0.035 14.8 1.5 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MADF_DNA_bdg PF10545.9 AAG04704.1 - 0.085 13.2 0.1 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MFS_1 PF07690.16 AAG04705.1 - 7e-52 176.5 51.9 7e-52 176.5 51.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG04705.1 - 6.5e-05 22.0 4.3 6.5e-05 22.0 4.3 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.19 AAG04705.1 - 0.0028 16.5 1.6 0.038 12.8 0.0 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter COX_ARM PF06481.14 AAG04706.1 - 6.5e-16 58.0 0.0 1.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 COX Aromatic Rich Motif COX2 PF00116.20 AAG04706.1 - 7.4e-08 32.3 0.1 4.7e-07 29.7 0.0 2.0 1 1 1 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain Sulf_transp PF04143.14 AAG04706.1 - 0.009 15.6 0.4 0.012 15.2 0.4 1.2 1 0 0 1 1 1 1 Sulphur transport DUF4079 PF13301.6 AAG04706.1 - 0.0091 16.2 0.8 0.022 14.9 0.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) TspO_MBR PF03073.15 AAG04706.1 - 0.018 15.1 3.9 0.018 15.1 3.9 2.2 2 0 0 2 2 2 0 TspO/MBR family AmoC PF04896.12 AAG04706.1 - 0.018 14.3 0.4 0.029 13.7 0.4 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C COX2_TM PF02790.15 AAG04706.1 - 5 7.3 9.3 0.095 12.9 2.2 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain COX1 PF00115.20 AAG04707.1 - 2.7e-135 451.6 66.2 2.7e-135 451.6 66.2 2.6 3 0 0 3 3 3 2 Cytochrome C and Quinol oxidase polypeptide I COX3 PF00510.18 AAG04708.1 - 4.8e-17 62.7 16.6 9.4e-17 61.7 16.6 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III COX4_pro PF03626.14 AAG04709.1 - 2.9e-17 62.9 13.9 3.9e-17 62.4 13.9 1.2 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV PhoLip_ATPase_C PF16212.5 AAG04709.1 - 0.047 13.4 9.4 0.052 13.3 9.4 1.0 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal EcsB PF05975.12 AAG04709.1 - 0.19 10.5 10.6 0.23 10.3 10.6 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB AC_N PF16214.5 AAG04709.1 - 0.65 9.1 6.3 0.75 8.9 6.3 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region ABC2_membrane_2 PF12679.7 AAG04709.1 - 3.1 7.0 13.8 0.76 9.0 10.1 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein UbiA PF01040.18 AAG04710.1 - 2.1e-57 194.3 26.6 2.6e-57 194.0 26.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TonB_dep_Rec PF00593.24 AAG04711.1 - 5.4e-62 211.2 25.5 8.1e-62 210.6 25.5 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG04711.1 - 4.5e-19 69.0 4.6 1e-18 67.9 4.6 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG04711.1 - 8.4e-05 21.7 0.0 0.00067 18.8 0.0 2.2 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family OMP_b-brl PF13505.6 AAG04711.1 - 0.77 9.9 12.3 0.79 9.8 0.4 4.2 5 0 0 5 5 5 0 Outer membrane protein beta-barrel domain DUF883 PF05957.13 AAG04712.1 - 4.7e-25 88.0 1.2 6.1e-25 87.6 1.0 1.2 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Peptidase_U40 PF10464.9 AAG04712.1 - 0.012 15.3 0.2 0.018 14.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase U40 CarboxypepD_reg PF13620.6 AAG04713.1 - 0.00011 22.4 0.4 0.00025 21.3 0.4 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 AAG04713.1 - 0.00011 22.4 0.1 0.0002 21.6 0.1 1.6 1 1 0 1 1 1 1 Prealbumin-like fold domain SdrD_B PF17210.3 AAG04713.1 - 0.0015 18.7 0.1 0.0031 17.7 0.1 1.6 1 0 0 1 1 1 1 SdrD B-like domain CarbopepD_reg_2 PF13715.6 AAG04713.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 0 CarboxypepD_reg-like domain SnoaL_3 PF13474.6 AAG04714.1 - 7.4e-10 39.1 0.1 9.9e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAG04714.1 - 8.5e-10 39.0 0.1 1e-09 38.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AAG04714.1 - 2.3e-07 31.4 0.9 2.7e-07 31.1 0.9 1.1 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 AAG04714.1 - 0.00033 21.2 0.0 0.00042 20.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 AAG04714.1 - 0.00056 20.0 0.8 0.00087 19.4 0.8 1.3 1 1 0 1 1 1 1 SnoaL-like domain PALP PF00291.25 AAG04715.1 - 9.9e-82 274.6 3.9 1.3e-81 274.3 3.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 AAG04715.1 - 6e-52 173.4 0.0 2.9e-25 87.8 0.0 2.6 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Glyco_transf_4 PF13439.6 AAG04715.1 - 0.0045 17.0 0.8 0.77 9.7 0.1 2.5 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Endonuclease_NS PF01223.23 AAG04716.1 - 3.1e-51 174.4 0.0 4.5e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Trypsin_2 PF13365.6 AAG04716.1 - 5.8e-20 72.7 0.2 2.1e-17 64.4 0.0 2.3 2 0 0 2 2 2 2 Trypsin-like peptidase domain Endonuclea_NS_2 PF13930.6 AAG04716.1 - 0.0034 17.5 0.0 0.0097 16.0 0.0 1.8 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Peptidase_S46 PF10459.9 AAG04716.1 - 0.0096 14.6 0.1 0.019 13.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase S46 Trypsin PF00089.26 AAG04716.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.7 1 1 0 1 1 1 0 Trypsin LysR_substrate PF03466.20 AAG04717.1 - 3.4e-36 124.6 9.0 4.9e-36 124.1 9.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04717.1 - 3.6e-20 71.7 4.5 3.7e-20 71.6 2.4 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AAG04717.1 - 0.0026 17.8 0.1 0.029 14.5 0.0 2.6 1 1 1 2 2 2 1 Helix-turn-helix domain SMC_ScpB PF04079.16 AAG04717.1 - 0.0044 16.6 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB P22_Cro PF14549.6 AAG04717.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro MarR_2 PF12802.7 AAG04717.1 - 0.017 15.0 0.3 0.068 13.1 0.1 2.1 2 0 0 2 2 2 0 MarR family Cro PF09048.10 AAG04717.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Cro Haem_degrading PF03928.14 AAG04718.1 - 1.6e-29 102.4 1.4 1.8e-29 102.2 1.4 1.0 1 0 0 1 1 1 1 Haem-degrading adh_short PF00106.25 AAG04719.1 - 6.5e-39 133.4 0.0 8.5e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG04719.1 - 6.9e-23 81.4 0.0 8.3e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG04719.1 - 2.2e-08 34.2 0.1 4.7e-08 33.1 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG04719.1 - 4.9e-07 29.4 0.0 1.3e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAG04719.1 - 1.8e-06 27.6 0.0 2.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Redoxin PF08534.10 AAG04719.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.7 2 0 0 2 2 2 0 Redoxin NAD_binding_10 PF13460.6 AAG04719.1 - 0.025 14.5 1.2 0.031 14.2 1.2 1.4 1 1 0 1 1 1 0 NAD(P)H-binding MccV PF17508.2 AAG04719.1 - 0.13 12.8 0.2 0.27 11.8 0.2 1.5 1 0 0 1 1 1 0 Microcin V bacteriocin TerC PF03741.16 AAG04720.1 - 9.1e-47 159.1 12.8 1.4e-46 158.5 12.8 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family CorC_HlyC PF03471.17 AAG04720.1 - 1.1e-18 66.9 0.2 2.5e-18 65.8 0.2 1.6 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AAG04720.1 - 5.9e-13 49.0 2.7 1.1e-07 32.1 0.0 3.2 4 0 0 4 4 4 2 CBS domain CitMHS PF03600.16 AAG04720.1 - 0.0017 17.6 8.1 0.0028 16.9 8.1 1.4 1 0 0 1 1 1 1 Citrate transporter DUF751 PF05421.11 AAG04720.1 - 7 7.5 8.5 36 5.2 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF751) Oxidored_FMN PF00724.20 AAG04723.1 - 6.5e-89 298.6 0.0 7.5e-89 298.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sigma54_activat PF00158.26 AAG04724.1 - 1.7e-66 223.0 0.0 2.6e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG04724.1 - 1.2e-24 87.0 0.0 4.8e-24 85.0 0.0 2.0 2 1 0 2 2 2 1 Sigma-54 interaction domain Response_reg PF00072.24 AAG04724.1 - 4.8e-22 78.2 0.0 9.8e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AAG04724.1 - 6.6e-09 35.4 0.3 2.3e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 AAG04724.1 - 1.2e-06 28.0 0.0 3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Mg_chelatase PF01078.21 AAG04724.1 - 5.9e-06 25.8 0.1 0.079 12.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AAG04724.1 - 1.7e-05 25.2 0.6 6.7e-05 23.3 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 AAG04724.1 - 3.4e-05 23.8 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AAG04724.1 - 0.00017 21.8 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 AAG04724.1 - 0.0024 18.3 0.0 0.0063 17.0 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TadZ_N PF16968.5 AAG04724.1 - 0.0057 16.4 0.3 0.018 14.7 0.1 1.9 2 0 0 2 2 2 1 Pilus assembly protein TadZ N-terminal AAA_3 PF07726.11 AAG04724.1 - 0.039 13.8 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2791 PF10923.8 AAG04724.1 - 0.048 12.5 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) MCM PF00493.23 AAG04724.1 - 0.084 12.0 0.0 0.4 9.8 0.0 1.9 1 1 0 1 1 1 0 MCM P-loop domain AAA_32 PF13654.6 AAG04724.1 - 0.17 10.7 0.1 1.1 8.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain dCache_1 PF02743.18 AAG04725.1 - 1.7e-20 73.9 0.0 7.6e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Cache domain HATPase_c PF02518.26 AAG04725.1 - 9.8e-20 71.1 0.0 2.4e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG04725.1 - 2.8e-06 27.3 0.4 2.8e-06 27.3 0.4 3.2 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain sCache_3_2 PF17203.4 AAG04725.1 - 0.00088 19.4 0.0 0.028 14.5 0.0 2.7 2 0 0 2 2 2 1 Single cache domain 3 HATPase_c_5 PF14501.6 AAG04725.1 - 0.0031 17.4 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAG04725.1 - 0.043 13.8 0.1 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain COG5 PF10392.9 AAG04725.1 - 0.11 12.7 0.5 0.23 11.6 0.5 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 HATPase_c_3 PF13589.6 AAG04725.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Asparaginase PF00710.20 AAG04726.1 - 3.1e-54 183.4 0.5 4.9e-54 182.8 0.5 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AAG04726.1 - 5.3e-21 75.0 3.4 6.8e-20 71.4 0.0 3.1 3 1 0 3 3 3 1 Glutaminase/Asparaginase C-terminal domain Glu_synthase PF01645.17 AAG04726.1 - 0.032 13.4 0.2 0.083 12.0 0.0 1.7 2 0 0 2 2 2 0 Conserved region in glutamate synthase G_glu_transpept PF01019.21 AAG04727.1 - 2.9e-175 583.9 0.1 3.3e-175 583.7 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ABC_tran PF00005.27 AAG04728.1 - 1.2e-34 119.7 0.0 1.7e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG04728.1 - 1.1e-08 35.3 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG04728.1 - 9.9e-08 31.7 0.1 1.5e-06 27.8 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 AAG04728.1 - 8.8e-05 22.5 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 AAG04728.1 - 0.00024 20.8 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG04728.1 - 0.00027 20.9 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAG04728.1 - 0.00032 21.0 0.2 0.0012 19.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG04728.1 - 0.00039 20.8 0.1 0.00074 19.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAG04728.1 - 0.0014 18.8 0.3 0.0018 18.5 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAG04728.1 - 0.0023 18.5 0.0 0.0041 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAG04728.1 - 0.0072 16.1 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AAG04728.1 - 0.01 15.2 0.3 0.14 11.5 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 AAG04728.1 - 0.011 15.9 0.2 0.42 10.9 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 AAG04728.1 - 0.012 14.5 0.2 2.7 6.7 0.1 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class ATPase_2 PF01637.18 AAG04728.1 - 0.018 14.9 0.0 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AAG04728.1 - 0.019 15.5 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAG04728.1 - 0.021 13.5 0.0 1 7.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 AAG04728.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAG04728.1 - 0.031 14.7 0.5 0.51 10.8 0.5 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAG04728.1 - 0.051 13.3 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 AAG04728.1 - 0.061 12.2 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RNA12 PF10443.9 AAG04728.1 - 0.067 11.9 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein AAA_25 PF13481.6 AAG04728.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAG04728.1 - 0.088 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 AAG04728.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 AAG04728.1 - 0.11 12.9 0.1 0.45 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 AAG04728.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 AAG04728.1 - 0.12 12.6 0.2 1.3 9.2 0.1 2.4 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 AAG04728.1 - 0.17 12.2 0.5 0.26 11.6 0.4 1.6 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAG04729.1 - 2.1e-20 73.2 12.6 2.1e-20 73.2 12.6 1.6 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG04730.1 - 6.8e-25 87.9 8.3 6.8e-25 87.9 8.3 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SPC25 PF06703.11 AAG04730.1 - 0.15 11.8 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SBP_bac_3 PF00497.20 AAG04731.1 - 5.4e-51 173.2 0.2 7.8e-51 172.7 0.2 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAG04731.1 - 0.00022 21.3 0.3 0.0005 20.1 0.3 1.6 1 1 0 1 1 1 1 NMT1/THI5 like TDH PF03347.13 AAG04731.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Lig_chan-Glu_bd PF10613.9 AAG04731.1 - 0.044 14.0 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Phage_TAC_9 PF10876.8 AAG04732.1 - 0.2 11.8 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC adh_short_C2 PF13561.6 AAG04733.1 - 5.3e-42 144.0 3.2 2.1e-41 142.0 3.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG04733.1 - 1e-37 129.5 0.3 1.5e-37 128.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG04733.1 - 0.00026 21.0 0.6 0.00079 19.4 0.3 1.8 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 AAG04733.1 - 0.031 14.2 0.8 0.34 10.8 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 AAG04733.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RLAN PF14401.6 AAG04734.1 - 1.8e-44 151.0 0.0 2.9e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain RimK PF08443.11 AAG04734.1 - 5.8e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAG04734.1 - 9.7e-06 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AAG04734.1 - 0.0097 16.0 0.0 0.066 13.3 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAG04734.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain R2K_2 PF18299.1 AAG04734.1 - 0.025 14.5 0.2 0.067 13.1 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 ATP-grasp PF02222.22 AAG04734.1 - 0.028 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 AAG04734.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp OKR_DC_1_C PF03711.15 AAG04735.1 - 4.1e-34 117.7 0.0 1.9e-33 115.5 0.0 2.0 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1 PF01276.20 AAG04735.1 - 7.9e-16 57.8 0.0 1.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_N PF03709.15 AAG04735.1 - 1.7e-08 34.7 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain GerE PF00196.19 AAG04736.1 - 1.7e-12 46.7 0.0 2.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family PAS_4 PF08448.10 AAG04736.1 - 1.7e-06 28.2 0.0 7.6e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 PAS fold Sigma70_r4_2 PF08281.12 AAG04736.1 - 0.00015 21.4 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG04736.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.16 AAG04736.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 YCII PF03795.14 AAG04738.1 - 8e-31 106.3 0.0 8.9e-31 106.2 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF899 PF05988.12 AAG04739.1 - 1.3e-96 322.3 0.1 1.5e-96 322.0 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.21 AAG04739.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AAG04739.1 - 0.025 14.9 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF3134 PF11332.8 AAG04739.1 - 0.11 12.8 2.0 15 6.0 0.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3134) Sigma70_r2 PF04542.14 AAG04740.1 - 2.6e-10 39.9 1.0 6.6e-10 38.6 1.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAG04740.1 - 6.7e-08 32.1 0.2 3.2e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 TPR_2 PF07719.17 AAG04740.1 - 0.00039 20.3 6.4 0.0017 18.3 2.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAG04740.1 - 0.0015 18.4 1.2 0.0015 18.4 1.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Sigma70_r4 PF04545.16 AAG04740.1 - 0.0033 16.9 0.1 0.15 11.6 0.1 2.9 2 0 0 2 2 2 1 Sigma-70, region 4 TPR_12 PF13424.6 AAG04740.1 - 0.006 16.9 11.2 0.015 15.6 1.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 AAG04740.1 - 0.0074 16.0 0.2 0.026 14.2 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 AAG04740.1 - 0.0078 16.3 0.2 0.2 11.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAG04740.1 - 0.015 15.1 0.8 0.42 10.5 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAG04740.1 - 0.016 16.0 3.4 0.016 16.0 3.4 6.5 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAG04740.1 - 1.1 9.3 9.4 0.9 9.5 2.9 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 AAG04741.1 - 5.6e-27 94.6 67.3 2.7e-22 79.2 47.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG04741.1 - 0.0038 16.1 11.0 0.0038 16.1 11.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter 3-dmu-9_3-mt PF06983.13 AAG04742.1 - 1.1e-10 42.1 0.0 1.8e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 AAG04742.1 - 9.3e-08 32.3 0.0 1e-07 32.2 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YCII PF03795.14 AAG04743.1 - 2.2e-31 108.1 0.1 3.2e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 YCII-related domain ThiS PF02597.20 AAG04744.1 - 1.1e-06 29.2 0.0 1.3e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 ThiS family Sortilin-Vps10 PF15902.5 AAG04745.1 - 2.3e-07 30.0 0.0 3e-05 23.0 0.0 2.8 1 1 2 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 AAG04745.1 - 0.00029 20.4 18.6 1.7 8.9 0.0 5.8 5 0 0 5 5 5 4 BNR/Asp-box repeat BNR_6 PF15899.5 AAG04745.1 - 0.01 15.8 4.8 0.032 14.3 0.2 3.6 4 0 0 4 4 4 0 BNR-Asp box repeat tRNA_edit PF04073.15 AAG04746.1 - 7.2e-26 90.7 0.5 8.4e-26 90.5 0.5 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain 3-dmu-9_3-mt PF06983.13 AAG04747.1 - 1.5e-32 112.5 0.0 1.7e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase HTH_3 PF01381.22 AAG04748.1 - 4.9e-13 48.9 0.0 8.7e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAG04748.1 - 1.1e-10 41.7 1.5 2.9e-10 40.4 1.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 AAG04748.1 - 9.7e-08 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_19 PF12844.7 AAG04748.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAG04748.1 - 2.7e-05 24.5 0.0 5.4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain AraC_binding_2 PF14525.6 AAG04748.1 - 0.00035 20.3 2.2 0.0008 19.1 0.1 2.1 1 1 1 2 2 2 1 AraC-binding-like domain HTH_25 PF13413.6 AAG04748.1 - 0.0014 18.5 0.1 0.012 15.4 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain AraC_binding PF02311.19 AAG04748.1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain ParBc PF02195.18 AAG04748.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 ParB-like nuclease domain HTH_37 PF13744.6 AAG04748.1 - 0.13 12.3 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain EamA PF00892.20 AAG04749.1 - 2e-22 79.8 36.0 1.6e-17 63.9 10.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 AAG04749.1 - 0.043 13.0 0.0 0.096 11.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-sugar transporter TPT PF03151.16 AAG04749.1 - 0.8 9.0 4.4 0.6 9.4 0.5 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family MatE PF01554.18 AAG04750.1 - 4.2e-70 234.6 24.2 4e-35 120.8 3.1 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 AAG04750.1 - 1.9e-07 31.2 10.6 1.9e-07 31.2 10.6 4.1 2 2 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Sigma70_r4_2 PF08281.12 AAG04752.1 - 4.3e-15 55.1 0.0 1.8e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG04752.1 - 1.7e-08 33.8 0.0 3.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG04752.1 - 0.0014 18.4 2.1 0.0019 17.9 1.0 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 HTH_24 PF13412.6 AAG04752.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 AAG04752.1 - 0.017 14.9 0.0 0.058 13.2 0.0 1.9 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_ISL3 PF13542.6 AAG04752.1 - 0.021 14.2 0.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_ECF PF07638.11 AAG04752.1 - 0.037 13.9 0.9 0.11 12.3 0.9 1.7 1 1 0 1 1 1 0 ECF sigma factor HTH_23 PF13384.6 AAG04752.1 - 0.04 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain GerE PF00196.19 AAG04752.1 - 0.051 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF1492 PF07374.11 AAG04752.1 - 0.095 12.9 0.0 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) KORA PF16509.5 AAG04752.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor FecR PF04773.13 AAG04753.1 - 5.8e-19 68.5 0.2 9.3e-19 67.9 0.2 1.3 1 0 0 1 1 1 1 FecR protein DUF4974 PF16344.5 AAG04753.1 - 0.0006 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) TonB_dep_Rec PF00593.24 AAG04754.1 - 7.1e-43 148.2 28.2 7.1e-43 148.2 28.2 1.7 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG04754.1 - 1.2e-18 67.6 1.2 3.3e-18 66.2 1.2 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG04754.1 - 1.5e-08 34.1 0.1 5.1e-08 32.3 0.1 1.8 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family STN PF07660.14 AAG04754.1 - 1e-07 31.6 0.1 1.1e-06 28.3 0.0 2.9 2 1 1 3 3 3 1 Secretin and TonB N terminus short domain Fic PF02661.18 AAG04755.1 - 1.3e-09 38.9 0.0 3.2e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family PhzC-PhzF PF02567.16 AAG04756.1 - 7.4e-50 170.0 0.0 9.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF1326 PF07040.11 AAG04756.1 - 0.17 11.9 0.0 0.82 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) DUF772 PF05598.11 AAG04757.1 - 4.1e-18 65.2 0.1 9e-18 64.1 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AAG04757.1 - 2.3e-15 56.9 0.0 4.7e-15 55.8 0.0 1.5 1 1 1 2 2 2 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AAG04757.1 - 5.8e-15 55.6 1.8 1.3e-14 54.5 0.2 2.2 2 0 0 2 2 2 1 Transposase DDE domain Dynamitin PF04912.14 AAG04757.1 - 0.012 15.0 2.8 1.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Dynamitin DUF501 PF04417.12 AAG04757.1 - 0.083 12.7 0.8 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Spectrin PF00435.21 AAG04758.1 - 0.055 14.0 0.3 6.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Spectrin repeat DUF4209 PF13910.6 AAG04759.1 - 0.0014 18.8 0.2 0.0033 17.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4209) AAA_lid_9 PF17871.1 AAG04759.1 - 0.086 12.8 0.1 0.29 11.1 0.1 1.9 1 0 0 1 1 1 0 AAA lid domain TPR_8 PF13181.6 AAG04759.1 - 0.21 11.9 0.8 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2290 PF10053.9 AAG04760.1 - 5.1e-14 52.2 0.2 7.6e-14 51.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2290) UvrD_C_2 PF13538.6 AAG04761.1 - 3.3e-09 36.4 0.2 3.3e-09 36.4 0.2 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 AAG04761.1 - 6.4e-05 22.6 0.0 0.0091 15.5 0.0 2.5 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAG04761.1 - 0.00014 22.2 0.0 0.00051 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 AAG04761.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AAG04761.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD_C PF13361.6 AAG04761.1 - 0.13 11.7 0.1 0.89 8.9 0.0 2.2 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain tRNA-synt_His PF13393.6 AAG04761.1 - 0.14 11.4 0.2 0.24 10.6 0.2 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase ketoacyl-synt PF00109.26 AAG04762.1 - 7.4e-60 202.6 2.4 7.4e-60 202.6 2.4 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAG04762.1 - 2.7e-32 111.3 4.2 2.7e-32 111.3 4.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AAG04762.1 - 5.2e-05 22.7 3.2 0.00011 21.7 0.3 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 AAG04762.1 - 0.022 14.6 1.4 0.74 9.7 0.9 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PBP_like PF12727.7 AAG04762.1 - 0.071 12.2 2.2 0.34 10.0 0.1 2.3 2 0 0 2 2 2 0 PBP superfamily domain HxlR PF01638.17 AAG04763.1 - 6.2e-19 67.6 0.0 9.7e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 AAG04763.1 - 0.00046 20.2 0.3 0.0021 18.0 0.0 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG04763.1 - 0.00089 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAG04763.1 - 0.0049 16.8 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_15 PF12324.8 AAG04763.1 - 0.0099 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of alkylmercury lyase TrmB PF01978.19 AAG04763.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AAG04763.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 AAG04763.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC 2-Hacid_dh_C PF02826.19 AAG04764.1 - 2.3e-35 121.6 0.0 4.2e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3410 PF11890.8 AAG04764.1 - 1.1e-22 79.6 0.0 2.1e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3410) 2-Hacid_dh PF00389.30 AAG04764.1 - 7.3e-15 54.8 0.0 8.8e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 AAG04764.1 - 2.2e-05 25.0 0.0 4.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain TrkA_N PF02254.18 AAG04764.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AceK PF06315.11 AAG04765.1 - 9.9e-241 800.1 0.0 1.1e-240 799.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) DnaB PF00772.21 AAG04765.1 - 0.17 12.0 0.0 0.56 10.3 0.0 1.9 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Acetyltransf_1 PF00583.25 AAG04766.1 - 2.2e-15 56.9 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAG04766.1 - 4.1e-14 53.4 0.0 4.9e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG04766.1 - 7.6e-11 42.3 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG04766.1 - 1.8e-10 40.8 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG04766.1 - 2.4e-10 40.8 0.0 3e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG04766.1 - 0.00029 20.5 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG04766.1 - 0.012 15.5 0.0 0.025 14.6 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein PocR PF10114.9 AAG04766.1 - 0.2 11.4 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR bPH_3 PF14470.6 AAG04767.1 - 0.0035 17.7 0.0 0.0044 17.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial PH domain bPH_6 PF10756.9 AAG04767.1 - 0.11 12.6 0.4 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial PH domain adh_short PF00106.25 AAG04768.1 - 2.9e-46 157.4 0.0 4e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG04768.1 - 9.7e-37 126.8 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG04768.1 - 3.4e-07 30.3 0.0 6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAG04768.1 - 0.00042 20.2 0.8 0.00062 19.7 0.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAG04768.1 - 0.00087 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG04768.1 - 0.021 14.0 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain LDcluster4 PF18306.1 AAG04768.1 - 0.082 12.5 0.2 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 SLOG cluster4 family AraC_N PF06719.13 AAG04769.1 - 2.5e-39 134.3 0.1 3.7e-39 133.7 0.1 1.3 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 AAG04769.1 - 2.3e-19 69.4 1.5 5.2e-19 68.3 1.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04769.1 - 1.2e-15 57.1 0.2 4.1e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 AAG04769.1 - 0.088 12.6 0.2 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family L27_1 PF09058.10 AAG04769.1 - 0.11 12.4 0.2 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 L27_1 T2SSC PF11356.8 AAG04770.1 - 0.0082 16.0 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Type II secretion system protein C Secretin PF00263.21 AAG04771.1 - 1.8e-44 151.4 0.3 2.9e-44 150.7 0.3 1.3 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAG04771.1 - 2.5e-20 72.6 18.3 7e-10 39.2 4.8 5.7 5 1 0 5 5 5 3 Bacterial type II/III secretion system short domain Ribosomal_S9 PF00380.19 AAG04772.1 - 0.098 13.2 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S9/S16 GDP_Man_Dehyd PF16363.5 AAG04773.1 - 6.8e-54 183.5 0.0 8e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAG04773.1 - 2.3e-49 168.0 0.0 2.9e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAG04773.1 - 1.8e-16 60.0 0.0 2.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAG04773.1 - 2.2e-15 56.6 0.0 3e-14 52.8 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AAG04773.1 - 4.3e-11 42.5 0.0 6.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAG04773.1 - 1.8e-10 40.4 0.1 1.6e-08 34.0 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 AAG04773.1 - 9.6e-08 32.1 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 AAG04773.1 - 6.2e-07 29.1 0.1 1.4e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG04773.1 - 8.1e-07 29.1 0.1 1.3e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 AAG04773.1 - 1.5e-05 24.7 0.1 0.00021 21.0 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family PCMT PF01135.19 AAG04773.1 - 0.019 14.7 1.4 0.72 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) adh_short_C2 PF13561.6 AAG04773.1 - 0.19 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glycos_transf_1 PF00534.20 AAG04774.1 - 4.7e-28 97.9 0.0 6.8e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG04774.1 - 2e-26 93.0 0.0 3.2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAG04774.1 - 0.00017 21.9 0.0 0.00031 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG04774.1 - 0.034 14.2 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Wzt_C PF14524.6 AAG04775.1 - 1.7e-19 70.3 0.0 2.9e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Wzt C-terminal domain ABC_tran PF00005.27 AAG04775.1 - 5.5e-19 69.0 0.0 1e-18 68.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 AAG04775.1 - 0.0023 18.2 0.3 0.012 15.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAG04775.1 - 0.0027 17.6 4.4 0.0038 17.1 0.4 2.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 AAG04775.1 - 0.008 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG04775.1 - 0.016 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 AAG04775.1 - 0.017 14.6 0.6 0.032 13.7 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAG04775.1 - 0.039 13.7 0.1 0.19 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAG04775.1 - 0.093 13.3 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAG04775.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 AAG04775.1 - 0.2 12.2 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG04775.1 - 0.22 11.2 0.0 0.31 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Sulfotransfer_3 PF13469.6 AAG04776.1 - 2.4e-17 64.1 0.3 2.7e-16 60.6 0.1 2.9 4 1 0 4 4 4 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 AAG04776.1 - 0.023 14.2 0.0 0.26 10.8 0.0 2.5 2 1 0 2 2 2 0 Sulfotransferase domain Glycos_transf_2 PF00535.26 AAG04777.1 - 1.3e-05 25.1 0.1 2.3e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AAG04777.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 VanY PF02557.17 AAG04777.1 - 0.059 13.2 0.2 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Glyco_trans_1_4 PF13692.6 AAG04778.1 - 8.1e-15 55.4 0.0 1.6e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAG04778.1 - 2.6e-13 49.9 0.0 5.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAG04778.1 - 6.9e-10 39.2 0.0 1.5e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Remorin_N PF03766.13 AAG04778.1 - 0.042 13.9 0.2 0.075 13.1 0.2 1.3 1 0 0 1 1 1 0 Remorin, N-terminal region BioY PF02632.14 AAG04778.1 - 0.23 11.5 0.1 0.41 10.7 0.1 1.3 1 0 0 1 1 1 0 BioY family Glycos_transf_2 PF00535.26 AAG04779.1 - 4.9e-28 98.1 0.0 7.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AAG04779.1 - 1.4e-13 50.9 0.0 3.7e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AAG04779.1 - 7.4e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAG04779.1 - 0.0017 18.9 0.0 0.0072 16.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAG04779.1 - 0.0048 16.8 1.1 0.017 15.0 1.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_1 PF00534.20 AAG04780.1 - 8.2e-28 97.1 0.0 1.1e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG04780.1 - 9.2e-25 87.6 0.1 2e-24 86.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG04780.1 - 4.8e-07 29.9 0.7 1.4e-06 28.4 0.5 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAG04780.1 - 2.5e-06 27.8 1.8 4.7e-06 26.9 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAG04780.1 - 1.6e-05 25.4 6.0 1.6e-05 25.4 6.0 3.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Sulfotransfer_3 PF13469.6 AAG04781.1 - 0.00016 22.1 1.8 0.53 10.6 0.1 3.0 3 0 0 3 3 3 2 Sulfotransferase family Tropomyosin_1 PF12718.7 AAG04781.1 - 0.0036 17.4 0.9 0.0067 16.6 0.9 1.4 1 0 0 1 1 1 1 Tropomyosin like GAS PF13851.6 AAG04781.1 - 0.053 12.9 0.6 0.095 12.0 0.6 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sulfotransfer_4 PF17784.1 AAG04781.1 - 0.14 12.0 0.1 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase domain APS_kinase PF01583.20 AAG04782.1 - 9.9e-67 223.7 0.0 1.2e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AAG04782.1 - 5.4e-08 33.1 0.0 7.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AAG04782.1 - 1e-06 28.2 0.0 1.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 AAG04782.1 - 1.7e-05 25.4 0.0 2.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAG04782.1 - 0.00016 22.2 0.1 0.00029 21.4 0.1 1.4 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 AAG04782.1 - 0.00052 19.8 0.0 0.00063 19.5 0.0 1.1 1 0 0 1 1 1 1 SWI2/SNF2 ATPase KTI12 PF08433.10 AAG04782.1 - 0.00061 19.3 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 AAG04782.1 - 0.001 19.5 0.0 0.0013 19.2 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG04782.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AAG04782.1 - 0.0083 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAG04782.1 - 0.0089 16.1 0.0 0.015 15.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 AAG04782.1 - 0.0093 16.5 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SRP54 PF00448.22 AAG04782.1 - 0.0095 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 AAG04782.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 AAG04782.1 - 0.016 15.0 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 AAG04782.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_22 PF13401.6 AAG04782.1 - 0.023 15.0 0.0 0.042 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAG04782.1 - 0.03 14.2 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase IstB_IS21 PF01695.17 AAG04782.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 AAG04782.1 - 0.05 12.8 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 AAG04782.1 - 0.058 13.1 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ResIII PF04851.15 AAG04782.1 - 0.072 13.1 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 AAG04782.1 - 0.075 12.6 0.5 0.2 11.2 0.3 1.6 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 AAG04782.1 - 0.076 12.2 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit CPT PF07931.12 AAG04782.1 - 0.085 12.7 0.5 0.34 10.7 0.5 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ArsA_ATPase PF02374.15 AAG04782.1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase RNA_helicase PF00910.22 AAG04782.1 - 0.15 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 AAG04782.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 AAG04782.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HATPase_c PF02518.26 AAG04785.1 - 6.8e-19 68.4 0.0 1.3e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG04785.1 - 5.6e-11 42.3 2.3 2.3e-10 40.4 0.7 2.7 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAG04785.1 - 1.8e-07 31.3 0.0 3.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DUF1003 PF06210.11 AAG04785.1 - 0.18 11.9 0.3 0.48 10.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DUF2070 PF09843.9 AAG04785.1 - 2.8 6.1 6.2 3.9 5.7 6.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Response_reg PF00072.24 AAG04786.1 - 3.7e-19 69.0 0.0 5.3e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG04786.1 - 3e-18 65.1 0.0 1.5e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AAG04786.1 - 1.4e-05 24.7 0.1 6.2e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AAG04786.1 - 0.00016 21.3 0.3 0.0004 20.0 0.2 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG04786.1 - 0.00018 20.9 0.6 0.00055 19.4 0.6 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AAG04786.1 - 0.0019 17.9 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2089 PF09862.9 AAG04786.1 - 0.023 14.7 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_20 PF12840.7 AAG04786.1 - 0.035 14.2 2.2 0.042 13.9 0.1 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_7 PF02796.15 AAG04786.1 - 0.072 13.2 0.0 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF742 PF05331.11 AAG04786.1 - 0.073 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_28 PF13518.6 AAG04786.1 - 0.096 12.8 0.0 0.31 11.2 0.0 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain Glyco_hydro_3_C PF01915.22 AAG04786.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain HTH_1 PF00126.27 AAG04788.1 - 2.4e-21 75.4 0.9 4.6e-21 74.5 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAG04788.1 - 1.2e-17 64.0 7.6 1.2e-17 64.0 7.6 2.0 2 0 0 2 2 2 1 LysR substrate binding domain HTH_5 PF01022.20 AAG04788.1 - 0.028 14.3 0.3 0.084 12.8 0.3 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Carboxyl_trans PF01039.22 AAG04789.1 - 1.9e-71 241.2 0.0 2.6e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 AAG04789.1 - 6.8e-58 195.6 0.0 1.4e-57 194.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAG04789.1 - 6.3e-42 142.6 0.0 4.5e-39 133.4 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAG04789.1 - 7.6e-30 103.2 0.0 9.6e-29 99.7 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AAG04789.1 - 3e-12 46.2 0.0 5.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAG04789.1 - 0.00021 21.0 0.0 0.00095 18.9 0.0 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 AAG04789.1 - 0.00024 20.7 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_D23 PF16576.5 AAG04789.1 - 0.004 16.4 0.0 0.45 9.7 0.0 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ECH_1 PF00378.20 AAG04789.1 - 0.011 15.0 1.6 0.021 14.2 1.6 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase HlyD_3 PF13437.6 AAG04789.1 - 0.022 15.5 0.0 7.4 7.3 0.0 2.8 2 0 0 2 2 2 0 HlyD family secretion protein ATP-grasp_3 PF02655.14 AAG04789.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain SnoaL PF07366.12 AAG04790.1 - 1.2e-38 131.7 0.0 1.4e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 AAG04790.1 - 3.2e-15 56.6 0.1 4e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAG04790.1 - 0.093 13.1 0.0 0.24 11.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) Methyltransf_24 PF13578.6 AAG04791.1 - 1.1e-15 58.5 0.0 1.7e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 AAG04791.1 - 5.2e-11 42.1 0.0 8e-11 41.5 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 AAG04791.1 - 5.1e-05 23.1 0.0 6.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG04791.1 - 0.00013 22.6 0.0 0.00024 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AAG04791.1 - 0.063 12.9 0.0 1.3 8.7 0.0 2.5 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 AAG04791.1 - 0.11 13.2 0.0 0.18 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TetR_C_18 PF17923.1 AAG04792.1 - 5.3e-51 171.9 3.0 5.3e-51 171.9 3.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAG04792.1 - 2.4e-15 56.1 0.3 4.5e-15 55.2 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 AAG04792.1 - 9.9e-13 48.8 6.2 9.9e-13 48.8 6.2 2.1 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_30 PF17939.1 AAG04792.1 - 0.018 15.3 3.3 0.11 12.7 0.5 2.9 1 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PRA-PH PF01503.17 AAG04792.1 - 0.055 13.9 0.4 1.9 9.0 0.4 2.3 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase UvrD-helicase PF00580.21 AAG04794.1 - 5.4e-26 91.8 0.0 8.9e-25 87.9 0.0 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAG04794.1 - 8.4e-19 68.3 0.0 9.6e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 AAG04794.1 - 7.5e-11 41.7 0.1 1.5e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 AAG04794.1 - 1.8e-09 37.5 0.0 0.00014 21.4 0.0 2.1 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain NTP_transf_2 PF01909.23 AAG04795.1 - 1.3e-05 25.4 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAG04795.1 - 1.5e-05 24.9 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Methyltrans_SAM PF10672.9 AAG04796.1 - 4.8e-171 567.4 0.0 5.5e-171 567.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AAG04796.1 - 6.4e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AAG04796.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 AAG04796.1 - 0.16 12.7 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MS_channel PF00924.18 AAG04797.1 - 1.3e-42 145.7 0.7 4.6e-42 143.9 0.7 2.0 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF3772 PF12607.8 AAG04797.1 - 1e-18 66.8 5.3 1e-18 66.8 5.3 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3772) Hist_deacetyl PF00850.19 AAG04798.1 - 3.3e-64 217.3 0.0 4e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain SBP_bac_8 PF13416.6 AAG04799.1 - 2e-31 109.9 0.0 2.4e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG04799.1 - 1.6e-19 70.3 0.9 3e-19 69.4 0.3 1.7 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG04799.1 - 1.4e-16 61.4 1.2 2.3e-16 60.7 1.2 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG04799.1 - 3.2e-07 30.3 0.1 4e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAG04799.1 - 0.0097 14.7 0.0 2.3 6.9 0.0 2.3 2 0 0 2 2 2 2 Hypothetical lipoprotein (MG045 family) Abhydrolase_6 PF12697.7 AAG04799.1 - 0.031 14.9 0.6 0.079 13.5 0.2 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family EamA PF00892.20 AAG04800.1 - 9.3e-37 126.3 39.0 4.3e-21 75.5 17.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 AAG04800.1 - 3.4 7.7 7.2 14 5.7 0.7 3.2 3 0 0 3 3 3 0 Putative transmembrane family 234 MFS_4 PF06779.14 AAG04801.1 - 2.1e-127 425.4 36.4 2.4e-127 425.2 36.4 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 AAG04801.1 - 3.1e-12 46.1 48.4 4e-07 29.3 20.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily LysR_substrate PF03466.20 AAG04802.1 - 3.6e-44 150.6 1.1 3.6e-44 150.6 1.1 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04802.1 - 8.1e-20 70.5 1.5 1.7e-19 69.5 1.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG04802.1 - 1e-05 25.3 0.1 1.8e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AAG04802.1 - 0.0093 16.0 0.8 0.025 14.6 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain SBP_bac_11 PF13531.6 AAG04802.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Lactamase_B PF00753.27 AAG04804.1 - 2.9e-21 76.4 2.8 3.7e-21 76.1 2.8 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG04804.1 - 0.00034 20.2 0.3 0.00048 19.7 0.3 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FAD-oxidase_C PF02913.19 AAG04805.1 - 1.6e-55 188.5 0.0 3e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAG04805.1 - 1.9e-33 115.1 2.2 3.3e-33 114.4 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_5 PF00941.21 AAG04805.1 - 0.023 14.5 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase TPP_enzyme_N PF02776.18 AAG04806.1 - 2.4e-56 190.0 0.6 1.3e-54 184.4 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAG04806.1 - 4.4e-34 117.5 0.0 1.4e-33 115.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG04806.1 - 8.5e-29 100.0 0.1 1.5e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 AAG04806.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SSF PF00474.17 AAG04807.1 - 4.3e-42 144.4 33.2 7.2e-42 143.7 33.2 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Transp_cyt_pur PF02133.15 AAG04808.1 - 1.2e-46 159.5 33.6 1.4e-46 159.2 33.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SnoaL_3 PF13474.6 AAG04809.1 - 2.8e-16 59.9 0.2 3.6e-16 59.5 0.2 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 AAG04809.1 - 9e-08 32.7 0.3 1.2e-07 32.4 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAG04809.1 - 1.2e-05 25.7 0.6 1.4e-05 25.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 AAG04809.1 - 0.0011 19.0 0.1 0.0015 18.7 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AAG04809.1 - 0.0034 17.5 0.0 0.0043 17.2 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Lysyl_oxidase PF01186.17 AAG04809.1 - 0.045 13.4 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Lysyl oxidase Arginase PF00491.21 AAG04810.1 - 8.4e-89 297.8 0.0 1e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 AAG04810.1 - 0.076 13.2 0.5 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 UPF0489 domain LysR_substrate PF03466.20 AAG04811.1 - 1.8e-37 128.8 2.2 2.6e-37 128.2 2.2 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04811.1 - 1.4e-16 60.2 0.4 3.6e-16 58.9 0.4 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MCPsignal PF00015.21 AAG04812.1 - 4.2e-41 140.6 18.9 4.6e-41 140.5 16.6 2.1 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AAG04812.1 - 2.6e-31 107.7 0.3 1.7e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAG04812.1 - 7.1e-30 103.3 0.0 2.5e-15 56.6 0.0 2.7 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 AAG04812.1 - 3.1e-28 98.2 1.9 2.5e-13 50.2 0.1 2.9 4 0 0 4 4 3 2 PAS fold PAS PF00989.25 AAG04812.1 - 5.7e-22 77.8 0.0 4.8e-13 49.1 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AAG04812.1 - 1.4e-10 40.9 0.7 1.7e-05 24.7 0.1 3.5 3 0 0 3 3 3 2 PAS domain SfsA_N PF17746.1 AAG04812.1 - 0.0074 16.4 0.0 0.66 10.2 0.0 2.6 2 0 0 2 2 2 1 SfsA N-terminal OB domain DUF5434 PF17502.2 AAG04812.1 - 0.031 14.3 1.6 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5434) Dak2 PF02734.17 AAG04812.1 - 0.065 13.1 2.2 0.08 12.8 1.2 1.7 1 1 0 1 1 1 0 DAK2 domain PAS_7 PF12860.7 AAG04812.1 - 0.076 13.2 0.7 3.6 7.8 0.0 3.5 3 1 1 4 4 4 0 PAS fold NPV_P10 PF05531.12 AAG04812.1 - 1.2 9.7 4.9 11 6.5 1.1 2.9 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 AAG04812.1 - 1.4 8.9 10.4 0.63 10.1 1.5 2.5 3 0 0 3 3 3 0 Laminin Domain II Syntaxin_2 PF14523.6 AAG04812.1 - 6.4 7.2 7.1 4.1 7.8 2.7 2.9 3 1 0 3 3 3 0 Syntaxin-like protein DUF1664 PF07889.12 AAG04812.1 - 7.4 6.6 6.8 21 5.1 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAG04812.1 - 9.9 6.5 10.7 5 7.5 0.7 3.7 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DTW PF03942.15 AAG04813.1 - 1.1e-48 165.6 0.0 1.2e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 DTW domain Mago-bind PF09282.10 AAG04813.1 - 0.034 14.0 1.6 0.037 13.9 0.2 1.8 2 0 0 2 2 2 0 Mago binding ABC_tran PF00005.27 AAG04814.1 - 6.7e-36 123.8 0.0 2.8e-16 60.3 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 AAG04814.1 - 7.1e-20 72.0 1.5 1.2e-06 28.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG04814.1 - 4.9e-15 55.6 0.0 6.7e-06 25.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG04814.1 - 3e-07 30.8 2.8 0.0016 18.7 0.0 3.4 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 AAG04814.1 - 8.7e-07 29.0 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 AAG04814.1 - 1.8e-06 28.4 22.2 8.9e-06 26.2 1.8 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAG04814.1 - 7.2e-06 25.7 0.1 0.0077 16.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAG04814.1 - 9.4e-06 25.7 0.0 0.046 13.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 AAG04814.1 - 2.2e-05 25.1 0.7 0.02 15.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 AAG04814.1 - 3.2e-05 24.3 0.2 0.78 10.2 0.0 3.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AAG04814.1 - 0.00017 22.1 0.6 1.1 9.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 AAG04814.1 - 0.00029 20.8 1.1 0.79 9.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 AAG04814.1 - 0.00038 20.3 0.0 0.18 11.5 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 AAG04814.1 - 0.00046 20.1 0.5 0.27 11.1 0.0 3.1 3 0 0 3 3 3 1 NACHT domain DUF87 PF01935.17 AAG04814.1 - 0.00055 20.1 0.1 0.43 10.6 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 AAG04814.1 - 0.0018 18.0 1.1 0.29 10.8 0.0 3.1 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 AAG04814.1 - 0.0025 18.2 0.1 2.6 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 AAG04814.1 - 0.0097 15.3 0.9 1.3 8.4 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAG04814.1 - 0.02 15.1 0.0 0.02 15.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 AAG04814.1 - 0.038 14.2 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 AAG04814.1 - 0.046 12.9 0.0 9.4 5.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 AAG04814.1 - 0.062 12.8 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 AAG04814.1 - 0.073 12.8 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 AAG04814.1 - 0.12 12.4 0.4 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 AAG04814.1 - 0.13 12.5 0.0 0.13 12.5 0.0 4.0 3 2 1 4 4 4 0 AAA domain AAA_25 PF13481.6 AAG04814.1 - 0.25 10.9 6.7 3.1 7.3 1.0 3.5 3 1 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 AAG04814.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase DUF3584 PF12128.8 AAG04814.1 - 1.6 6.2 17.8 1.4 6.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 AAG04814.1 - 1.9 7.1 5.9 3.4 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran_Xtn PF12848.7 AAG04814.1 - 6.2 6.9 16.1 0.17 12.0 9.4 1.9 2 1 0 2 2 1 0 ABC transporter DUF4088 PF13317.6 AAG04815.1 - 0.016 14.8 0.3 0.026 14.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Acetyltransf_10 PF13673.7 AAG04817.1 - 2.8e-16 59.6 0.0 3.2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG04817.1 - 1e-12 48.3 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG04817.1 - 4.8e-09 36.5 0.0 8.3e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 AAG04817.1 - 0.0026 17.5 0.1 0.011 15.5 0.1 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 AAG04817.1 - 0.0081 16.1 0.1 0.031 14.3 0.1 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAG04817.1 - 0.013 15.6 0.1 0.034 14.2 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AAG04817.1 - 0.036 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 AAG04817.1 - 0.058 14.1 0.0 0.092 13.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG04817.1 - 0.087 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase E1-E2_ATPase PF00122.20 AAG04818.1 - 3.8e-53 179.7 4.1 3.8e-52 176.4 0.4 2.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AAG04818.1 - 5e-45 153.4 2.5 5e-45 153.4 2.5 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AAG04818.1 - 3.6e-22 79.7 5.1 3.2e-21 76.6 5.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AAG04818.1 - 5.9e-20 71.2 0.0 1.1e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 AAG04818.1 - 2.4e-16 59.2 0.0 7.3e-16 57.6 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 AAG04818.1 - 1.1e-07 31.9 1.4 4.6e-07 29.8 1.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG04818.1 - 0.0001 22.8 0.4 0.00034 21.1 0.4 2.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FA_desaturase PF00487.24 AAG04818.1 - 4.1 7.2 12.9 9.4 6.0 1.1 3.4 3 0 0 3 3 3 0 Fatty acid desaturase Autoind_bind PF03472.15 AAG04819.1 - 6.4e-37 126.3 0.1 8.8e-37 125.9 0.1 1.1 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AAG04819.1 - 3.2e-22 77.8 0.1 6e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG04819.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.6 AAG04820.1 - 0.08 13.3 0.0 0.1 13.0 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain Autoind_synth PF00765.17 AAG04821.1 - 8.9e-31 106.8 0.0 1e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Autoinducer synthase Acetyltransf_5 PF13444.6 AAG04821.1 - 1.7e-05 25.4 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EAL PF00563.20 AAG04822.1 - 2.4e-46 158.2 0.2 5.8e-46 156.9 0.2 1.7 2 0 0 2 2 2 1 EAL domain LapD_MoxY_N PF16448.5 AAG04822.1 - 4.2e-41 139.7 0.0 8.3e-41 138.8 0.0 1.5 1 0 0 1 1 1 1 LapD/MoxY periplasmic domain GGDEF PF00990.21 AAG04822.1 - 2.4e-27 95.7 0.1 6.3e-27 94.3 0.0 1.7 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain HAMP PF00672.25 AAG04822.1 - 4e-07 30.3 1.7 4e-07 30.3 1.7 2.7 3 0 0 3 3 3 1 HAMP domain LAL_C2 PF18603.1 AAG04822.1 - 0.12 12.6 0.4 11 6.3 0.1 2.7 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Peptidase_C93 PF06035.11 AAG04823.1 - 1.3e-17 64.1 0.0 1.9e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial transglutaminase-like cysteine proteinase BTLCP Transglut_core PF01841.19 AAG04823.1 - 0.003 18.0 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily HlyD_D23 PF16576.5 AAG04824.1 - 8.1e-18 64.4 4.6 1.1e-17 63.9 4.6 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG04824.1 - 5.3e-15 56.0 1.9 1.1e-08 35.7 0.0 2.7 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG04824.1 - 4.1e-13 48.9 8.8 2.4e-11 43.3 3.8 3.3 2 1 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG04824.1 - 8e-05 22.4 0.2 0.013 15.3 0.1 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme OEP PF02321.18 AAG04824.1 - 0.0036 17.1 15.3 0.0067 16.2 15.3 1.4 1 0 0 1 1 1 1 Outer membrane efflux protein Peptidase_M23 PF01551.22 AAG04824.1 - 0.0084 16.3 0.1 0.29 11.4 0.0 2.6 2 0 0 2 2 2 1 Peptidase family M23 PTS_EIIA_1 PF00358.20 AAG04824.1 - 0.033 14.0 0.1 0.2 11.4 0.0 2.1 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF1206 PF06724.11 AAG04824.1 - 0.042 13.9 7.8 0.12 12.5 7.8 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF5580 PF17743.1 AAG04824.1 - 0.088 11.3 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) ACR_tran PF00873.19 AAG04825.1 - 9.9e-296 983.6 17.6 1.1e-295 983.4 17.6 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG04825.1 - 3.7e-09 36.0 33.4 6.2e-09 35.2 16.4 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAG04825.1 - 1.2e-05 24.7 18.4 1.2e-05 24.7 18.4 2.3 2 0 0 2 2 2 2 Protein export membrane protein Man-6-P_recep PF02157.15 AAG04825.1 - 0.23 10.5 0.3 0.63 9.1 0.3 1.7 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Response_reg PF00072.24 AAG04826.1 - 6.3e-26 90.7 0.0 9.2e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG04826.1 - 1.5e-23 82.7 0.0 3.1e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AAG04827.1 - 4e-16 59.5 0.0 8.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG04827.1 - 5.1e-15 55.3 1.2 5.1e-15 55.3 1.2 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAG04827.1 - 1.5e-08 34.9 2.2 1.2e-07 32.0 0.2 3.2 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.6 AAG04827.1 - 0.0028 17.5 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAG04827.1 - 0.012 15.5 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF454 PF04304.13 AAG04828.1 - 4.6e-41 139.4 2.6 5.5e-41 139.2 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF454) CPP1-like PF11833.8 AAG04828.1 - 0.19 11.4 0.4 0.68 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF308 PF03729.13 AAG04828.1 - 1.8 9.0 9.2 0.49 10.8 4.1 2.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) UPF0149 PF03695.13 AAG04829.1 - 6.3e-32 111.2 4.1 7.1e-32 111.1 4.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) Flg_hook PF02120.16 AAG04830.1 - 1.1e-22 79.7 1.0 1.1e-22 79.7 1.0 2.1 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK FliL PF03748.14 AAG04831.1 - 2.1e-23 82.8 0.3 2.1e-23 82.8 0.3 1.4 2 0 0 2 2 2 1 Flagellar basal body-associated protein FliL FliM PF02154.15 AAG04832.1 - 3.4e-75 252.2 0.2 4.6e-75 251.7 0.2 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 AAG04832.1 - 7.8e-17 61.1 0.3 1.5e-16 60.1 0.3 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliMN_C PF01052.20 AAG04833.1 - 5.2e-25 87.3 1.5 6.7e-25 86.9 1.5 1.2 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliO PF04347.13 AAG04834.1 - 7.2e-20 71.1 0.1 1.1e-19 70.4 0.1 1.3 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO FliP PF00813.20 AAG04835.1 - 2.6e-79 265.5 19.9 3.4e-79 265.2 19.9 1.1 1 0 0 1 1 1 1 FliP family Bac_export_3 PF01313.19 AAG04836.1 - 3e-29 100.7 9.3 3.6e-29 100.5 9.3 1.1 1 0 0 1 1 1 1 Bacterial export proteins, family 3 XK-related PF09815.9 AAG04836.1 - 0.005 16.0 1.4 0.0054 15.8 1.4 1.0 1 0 0 1 1 1 1 XK-related protein DUF3754 PF12576.8 AAG04836.1 - 0.024 14.6 0.7 0.032 14.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) TLV_coat PF00429.19 AAG04836.1 - 0.84 8.2 2.7 0.79 8.3 2.7 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Bac_export_2 PF01312.19 AAG04836.1 - 2 7.6 6.3 7.6 5.6 2.1 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family Bac_export_1 PF01311.20 AAG04837.1 - 1.1e-67 227.9 33.9 1.3e-67 227.8 33.9 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_2 PF01312.19 AAG04838.1 - 4.6e-126 420.5 1.8 5.2e-126 420.3 1.8 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Zip PF02535.22 AAG04838.1 - 0.011 15.0 0.2 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter BatA PF07584.11 AAG04838.1 - 0.046 14.1 5.7 0.19 12.1 5.7 2.1 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal TatC PF00902.18 AAG04838.1 - 0.063 13.1 0.8 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) TPM_phosphatase PF04536.14 AAG04839.1 - 6.6e-38 129.7 0.0 8.6e-38 129.3 0.0 1.2 1 0 0 1 1 1 1 TPM domain MOLO1 PF17175.4 AAG04839.1 - 0.016 15.3 0.0 0.061 13.4 0.0 1.8 1 1 0 1 1 1 0 Modulator of levamisole receptor-1 Ca_hom_mod PF14798.6 AAG04839.1 - 0.25 10.4 2.0 0.47 9.5 2.0 1.4 1 0 0 1 1 1 0 Calcium homeostasis modulator TPM_phosphatase PF04536.14 AAG04840.1 - 1.4e-37 128.7 0.1 2e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 TPM domain DUF5325 PF17259.2 AAG04840.1 - 0.15 11.9 1.2 0.64 9.9 1.2 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5325) FHIPEP PF00771.20 AAG04841.1 - 2.1e-267 888.9 9.5 2.5e-267 888.7 9.5 1.0 1 0 0 1 1 1 1 FHIPEP family Phage_holin_2_4 PF16082.5 AAG04841.1 - 0.18 11.5 2.2 2.3 8.0 0.1 3.0 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like SRP54 PF00448.22 AAG04842.1 - 3.6e-40 137.7 0.0 5.1e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 AAG04842.1 - 0.00016 22.0 0.0 0.00069 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG04842.1 - 0.00037 20.3 1.0 0.002 17.9 0.9 2.4 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AAG04842.1 - 0.0017 18.9 0.1 0.0049 17.4 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 AAG04842.1 - 0.0064 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAG04842.1 - 0.012 15.2 1.9 0.012 15.2 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAG04842.1 - 0.016 15.5 0.3 0.14 12.4 0.3 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAG04842.1 - 0.017 15.5 0.5 0.017 15.5 0.5 2.2 2 1 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 AAG04842.1 - 0.019 15.0 0.1 0.15 12.1 0.1 2.1 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 AAG04842.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 AAG04842.1 - 0.062 13.4 0.5 0.87 9.6 0.5 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 AAG04842.1 - 0.065 12.6 0.1 0.065 12.6 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.15 AAG04842.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AAG04842.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 AAG04842.1 - 0.13 12.3 0.0 0.48 10.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Terminase_6 PF03237.15 AAG04842.1 - 0.19 11.4 0.1 0.41 10.3 0.1 1.5 1 0 0 1 1 1 0 Terminase-like family AAA_24 PF13479.6 AAG04842.1 - 0.19 11.4 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAG04842.1 - 0.2 12.1 0.2 0.56 10.6 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAG04842.1 - 0.24 11.3 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 AAG04842.1 - 0.39 10.9 2.9 0.29 11.3 0.2 2.3 3 1 0 3 3 2 0 AAA domain ParA PF10609.9 AAG04843.1 - 4.9e-25 88.4 0.5 7.9e-25 87.7 0.5 1.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AAG04843.1 - 1.2e-19 70.7 0.0 2e-19 69.9 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAG04843.1 - 2.6e-15 56.8 0.0 3.9e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 AAG04843.1 - 2.7e-12 46.7 0.1 8.5e-12 45.1 0.1 1.8 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AAG04843.1 - 3.1e-07 30.1 1.8 1.1e-06 28.3 1.8 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AAG04843.1 - 5.4e-07 29.1 2.2 1.7e-06 27.4 0.3 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 AAG04843.1 - 3.3e-06 26.6 0.6 8.7e-06 25.2 0.6 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 AAG04843.1 - 0.00031 20.6 0.7 0.089 12.6 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 AAG04843.1 - 0.0019 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain VirC1 PF07015.11 AAG04843.1 - 0.012 15.0 0.4 0.038 13.3 0.2 1.8 2 0 0 2 2 2 0 VirC1 protein AAA_25 PF13481.6 AAG04843.1 - 0.031 13.9 1.7 0.096 12.3 1.2 2.2 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 AAG04843.1 - 0.048 13.4 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FTHFS PF01268.19 AAG04843.1 - 0.086 11.0 0.1 0.12 10.6 0.1 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase APS_kinase PF01583.20 AAG04843.1 - 0.15 11.9 0.6 0.41 10.5 0.1 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma70_r2 PF04542.14 AAG04844.1 - 7.5e-21 73.7 0.1 8.7e-20 70.3 0.0 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG04844.1 - 9.6e-20 69.9 1.3 1.2e-18 66.4 0.5 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 AAG04844.1 - 7.3e-11 42.0 1.7 1.1e-09 38.3 0.0 2.7 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 AAG04844.1 - 9e-10 38.1 0.4 1.9e-09 37.1 0.4 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG04844.1 - 6.9e-05 22.5 0.6 0.0004 20.1 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain UPF0122 PF04297.14 AAG04844.1 - 0.0023 18.1 0.0 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_30 PF13556.6 AAG04844.1 - 0.0023 17.7 0.1 0.028 14.2 0.1 2.3 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG04844.1 - 0.019 14.8 2.4 0.22 11.4 0.1 2.7 3 0 0 3 3 3 0 MarR family HTH_38 PF13936.6 AAG04844.1 - 0.023 14.4 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AAG04844.1 - 0.031 14.1 0.3 0.098 12.5 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain GerE PF00196.19 AAG04844.1 - 0.037 13.6 0.0 0.093 12.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAG04845.1 - 3e-31 107.9 0.1 3.4e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Glycos_transf_1 PF00534.20 AAG04845.1 - 0.063 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 CheZ PF04344.13 AAG04846.1 - 3.1e-75 252.5 4.8 3.2e-75 252.5 4.1 1.3 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ Mer2 PF09074.10 AAG04846.1 - 0.0015 18.4 1.0 0.32 10.8 0.6 2.9 1 1 2 3 3 3 2 Mer2 ApoLp-III PF07464.11 AAG04846.1 - 0.0044 17.1 2.3 9.5 6.3 0.0 3.7 1 1 0 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Rsd_AlgQ PF04353.13 AAG04846.1 - 0.0049 16.8 0.2 0.011 15.7 0.2 1.6 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ OmpH PF03938.14 AAG04846.1 - 0.014 15.7 2.7 0.37 11.1 0.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) phage_tail_N PF08400.10 AAG04846.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Ran-binding PF05508.11 AAG04846.1 - 0.018 14.0 1.7 0.13 11.3 0.1 2.2 1 1 1 2 2 2 0 RanGTP-binding protein Apolipoprotein PF01442.18 AAG04846.1 - 0.022 14.7 8.3 0.052 13.4 6.5 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ArnB_C PF18677.1 AAG04846.1 - 0.05 13.7 2.0 6.5 6.9 0.2 3.3 2 1 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain Sec20 PF03908.13 AAG04846.1 - 0.32 10.9 1.8 3 7.8 0.1 2.8 3 0 0 3 3 3 0 Sec20 CorA PF01544.18 AAG04846.1 - 0.73 9.1 4.4 0.93 8.7 0.9 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CheW PF01584.19 AAG04847.1 - 1.4e-24 86.3 0.4 2.4e-24 85.5 0.4 1.4 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AAG04847.1 - 4.7e-18 65.2 3.5 8.9e-18 64.3 0.6 2.9 2 0 0 2 2 2 1 Hpt domain HATPase_c PF02518.26 AAG04847.1 - 1.7e-16 60.7 0.1 4.1e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAG04847.1 - 1.4e-14 54.2 2.3 5.6e-14 52.3 2.3 2.1 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain SHOCT PF09851.9 AAG04847.1 - 9.8e-06 25.1 8.8 2.2 8.1 0.1 4.6 4 0 0 4 4 4 4 Short C-terminal domain HATPase_c_3 PF13589.6 AAG04847.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ORF_12_N PF18042.1 AAG04847.1 - 0.21 12.0 3.8 0.4 11.1 0.5 3.2 3 1 1 4 4 4 0 ORF 12 gene product N-terminal Snf7 PF03357.21 AAG04847.1 - 2 8.0 11.0 2.8 7.5 0.9 4.2 3 1 2 5 5 5 0 Snf7 CheB_methylest PF01339.17 AAG04848.1 - 1.3e-57 194.2 0.0 4.3e-57 192.5 0.0 1.8 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AAG04848.1 - 3.9e-21 75.3 0.0 7.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain AlaDh_PNT_C PF01262.21 AAG04848.1 - 0.043 13.1 0.2 0.076 12.3 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XPC-binding PF09280.11 AAG04848.1 - 0.062 13.0 0.1 0.52 10.1 0.1 2.1 2 0 0 2 2 2 0 XPC-binding domain MotA_ExbB PF01618.16 AAG04849.1 - 4.8e-29 100.7 0.1 4.8e-29 100.7 0.1 2.3 2 1 0 2 2 2 1 MotA/TolQ/ExbB proton channel family DUF3784 PF12650.7 AAG04849.1 - 2.2 8.6 5.2 0.78 10.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) MotB_plug PF13677.6 AAG04850.1 - 2.4e-22 78.3 0.1 7.9e-22 76.6 0.0 1.8 2 0 0 2 2 2 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AAG04850.1 - 2.2e-17 63.2 0.0 4.8e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 OmpA family AAA_31 PF13614.6 AAG04851.1 - 1e-41 142.8 0.0 1.3e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAG04851.1 - 4.5e-21 75.2 0.0 5.6e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAG04851.1 - 1.7e-09 37.5 0.1 2.2e-07 30.6 0.1 2.4 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAG04851.1 - 3.8e-09 36.2 0.0 4.5e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 ATPase MipZ ArsA_ATPase PF02374.15 AAG04851.1 - 1.6e-08 34.1 0.9 3.9e-08 32.9 0.1 1.9 2 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AAG04851.1 - 1.5e-05 24.6 0.1 7.1e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 AAG04851.1 - 0.00011 21.5 0.0 0.00036 19.9 0.0 1.8 2 0 0 2 2 2 1 VirC1 protein Fer4_NifH PF00142.18 AAG04851.1 - 0.00021 20.9 0.0 0.001 18.6 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 AAG04851.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 AAG04851.1 - 0.029 13.4 0.1 0.05 12.6 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 AAG04851.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CheW PF01584.19 AAG04852.1 - 1.2e-13 50.9 0.0 2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 CheW-like domain SRP68 PF16969.5 AAG04852.1 - 0.14 11.1 0.4 0.19 10.7 0.4 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 CheW PF01584.19 AAG04853.1 - 6.9e-40 135.9 0.9 7.7e-40 135.7 0.9 1.0 1 0 0 1 1 1 1 CheW-like domain Biotin_lipoyl PF00364.22 AAG04853.1 - 0.099 12.5 2.5 4.3 7.2 0.1 2.3 1 1 1 2 2 2 0 Biotin-requiring enzyme DUF2802 PF10975.8 AAG04854.1 - 4.6e-23 81.1 0.6 4.6e-23 81.1 0.6 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2802) HemX PF04375.14 AAG04854.1 - 0.0041 16.5 4.2 0.0044 16.3 4.2 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Nup54 PF13874.6 AAG04854.1 - 0.0052 16.9 2.0 0.0081 16.3 2.0 1.3 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 MAD PF05557.13 AAG04854.1 - 0.013 13.9 0.4 0.017 13.5 0.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein MscS_porin PF12795.7 AAG04854.1 - 0.016 14.8 5.6 0.026 14.1 5.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Ada3 PF10198.9 AAG04854.1 - 0.026 14.7 2.4 0.038 14.1 2.4 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 GspL_C PF12693.7 AAG04854.1 - 0.04 13.8 5.4 0.049 13.5 5.4 1.2 1 0 0 1 1 1 0 GspL periplasmic domain Jnk-SapK_ap_N PF09744.9 AAG04854.1 - 0.048 13.9 2.8 0.058 13.6 2.8 1.2 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 AAG04854.1 - 0.06 12.2 0.3 0.077 11.9 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.14 AAG04854.1 - 0.07 13.5 2.7 0.12 12.7 2.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 AAG04854.1 - 0.074 13.7 4.8 0.61 10.7 1.9 2.3 1 1 1 2 2 2 0 SlyX GIT_CC PF16559.5 AAG04854.1 - 0.1 12.5 1.1 3.6 7.5 0.1 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RskA PF10099.9 AAG04854.1 - 1.1 9.5 5.8 0.27 11.5 2.4 1.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4404 PF14357.6 AAG04854.1 - 1.6 9.5 5.5 1.1 10.0 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) LapA_dom PF06305.11 AAG04854.1 - 5.7 6.8 11.4 1e+02 2.8 11.4 2.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FlgM PF04316.13 AAG04854.1 - 6.1 7.3 7.3 19 5.7 2.7 2.8 2 1 1 3 3 3 0 Anti-sigma-28 factor, FlgM GST_C PF00043.25 AAG04855.1 - 1.5e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAG04855.1 - 5.5e-09 35.9 2.7 6.3e-09 35.7 1.4 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AAG04855.1 - 5.4e-07 29.9 0.0 9.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG04855.1 - 2.4e-06 27.7 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AAG04855.1 - 2.1e-05 24.6 0.0 3.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAG04855.1 - 8.8e-05 22.8 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 AAG04855.1 - 0.019 14.7 0.0 0.063 13.1 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WYL PF13280.6 AAG04856.1 - 5.9e-33 114.3 0.7 7.8e-33 113.9 0.7 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 AAG04856.1 - 4.7e-16 58.5 0.4 1e-15 57.4 0.4 1.6 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 AAG04856.1 - 3.1e-06 27.4 1.3 6.1e-06 26.5 0.1 2.1 2 1 0 2 2 2 1 Transcriptional regulator HTH_DeoR PF08220.12 AAG04856.1 - 5.9e-05 22.7 0.2 0.00013 21.7 0.2 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 AAG04856.1 - 7.3e-05 22.3 0.5 0.00017 21.1 0.5 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AAG04856.1 - 0.00033 20.6 0.5 0.00094 19.2 0.5 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_IclR PF09339.10 AAG04856.1 - 0.00033 20.4 1.4 0.00033 20.4 1.4 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 AAG04856.1 - 0.0086 15.9 1.3 0.0086 15.9 1.3 2.8 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_39 PF14090.6 AAG04856.1 - 0.017 14.8 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AAG04856.1 - 0.03 14.2 0.1 0.069 13.1 0.1 1.6 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 AAG04856.1 - 0.05 13.4 1.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain TFIIE_alpha PF02002.17 AAG04856.1 - 0.067 13.1 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit HrcA_DNA-bdg PF03444.15 AAG04856.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_36 PF13730.6 AAG04856.1 - 0.2 11.7 0.0 0.47 10.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 AAG04856.1 - 1.6 8.9 8.5 0.089 12.9 1.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain Cu-oxidase_4 PF02578.15 AAG04858.1 - 5.1e-46 157.1 0.2 6.3e-46 156.8 0.2 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Raf1_HTH PF18579.1 AAG04858.1 - 0.098 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain adh_short_C2 PF13561.6 AAG04859.1 - 4.3e-61 206.4 3.6 4.9e-61 206.3 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG04859.1 - 2.3e-46 157.7 1.9 2.7e-46 157.5 1.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG04859.1 - 1e-11 45.1 0.6 1.4e-11 44.6 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG04859.1 - 7.4e-06 25.6 0.3 1.1e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 AAG04859.1 - 0.00033 21.6 2.9 0.98 10.5 1.6 2.3 2 0 0 2 2 2 2 LytR cell envelope-related transcriptional attenuator NAD_binding_10 PF13460.6 AAG04859.1 - 0.0016 18.3 2.7 0.0026 17.7 2.7 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAG04859.1 - 0.039 13.5 1.6 0.063 12.8 1.6 1.3 1 0 0 1 1 1 0 NmrA-like family Acetyltransf_3 PF13302.7 AAG04861.1 - 2.2e-35 122.4 0.0 2.6e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG04861.1 - 2.8e-07 30.8 0.0 3.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAG04861.1 - 3.3e-06 26.9 0.1 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG04861.1 - 2.4e-05 24.5 0.0 2.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Bac_export_2 PF01312.19 AAG04862.1 - 1.8e-16 60.3 1.9 2.2e-16 60.0 1.9 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Flg_hook PF02120.16 AAG04863.1 - 1.2e-19 69.9 1.4 4.5e-19 68.1 0.0 2.6 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK Trans_reg_C PF00486.28 AAG04863.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal ABC_tran PF00005.27 AAG04864.1 - 3.4e-29 102.1 0.0 4.3e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG04864.1 - 1.7e-07 31.4 0.1 6.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG04864.1 - 7.6e-06 25.5 0.0 0.052 13.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG04864.1 - 0.00038 20.9 0.2 0.00056 20.3 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG04864.1 - 0.0028 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AAG04864.1 - 0.0076 15.9 0.1 0.76 9.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF3584 PF12128.8 AAG04864.1 - 0.012 13.2 0.0 0.016 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_15 PF13175.6 AAG04864.1 - 0.027 14.2 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AAG04864.1 - 0.038 13.7 0.0 0.075 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAG04864.1 - 0.04 14.4 0.0 0.053 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAG04864.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 AAG04864.1 - 0.12 12.9 0.0 1.1 9.9 0.0 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 AAG04864.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 AAG04864.1 - 0.14 12.4 0.1 0.26 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAG04864.1 - 0.28 11.4 0.8 0.52 10.5 0.1 2.1 3 1 0 3 3 3 0 AAA domain CcmB PF03379.13 AAG04865.1 - 2.8e-83 278.7 29.6 3.3e-83 278.4 29.6 1.0 1 0 0 1 1 1 1 CcmB protein ABC2_membrane PF01061.24 AAG04865.1 - 1.8e-06 27.5 10.4 2.8e-06 26.9 10.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAG04865.1 - 0.79 8.8 18.6 0.19 10.8 14.0 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein Cytochrom_C_asm PF01578.20 AAG04866.1 - 6.7e-26 91.4 22.8 6.7e-26 91.4 22.8 1.8 2 0 0 2 2 2 1 Cytochrome C assembly protein Ycf70 PF17382.2 AAG04866.1 - 0.041 14.3 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized Ycf70-like CcmD PF04995.14 AAG04867.1 - 1.4e-17 63.4 0.9 1.7e-17 63.2 0.9 1.1 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF347 PF03988.12 AAG04867.1 - 0.034 14.3 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) CcmE PF03100.15 AAG04868.1 - 2.2e-47 160.3 0.0 2.6e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 CcmE LapA_dom PF06305.11 AAG04868.1 - 0.034 14.0 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GNVR PF13807.6 AAG04868.1 - 0.094 12.6 0.6 0.17 11.8 0.6 1.3 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase CcmF_C PF16327.5 AAG04869.1 - 8e-128 426.2 8.0 8e-128 426.2 8.0 1.8 2 0 0 2 2 2 1 Cytochrome c-type biogenesis protein CcmF C-terminal Cytochrom_C_asm PF01578.20 AAG04869.1 - 7.8e-56 189.2 21.6 7.8e-56 189.2 21.6 2.7 2 1 0 2 2 2 1 Cytochrome C assembly protein ResB PF05140.14 AAG04869.1 - 0.074 11.8 1.8 4.2 6.0 0.4 2.5 1 1 0 2 2 2 0 ResB-like family Redoxin PF08534.10 AAG04870.1 - 1.1e-20 73.9 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAG04870.1 - 5.8e-17 61.8 0.0 7.4e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 AAG04870.1 - 3.6e-05 24.2 0.0 7.4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AAG04870.1 - 0.0002 21.6 0.0 0.00032 21.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AAG04870.1 - 0.00029 20.8 0.0 0.0016 18.4 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin zf-TFIIB PF13453.6 AAG04870.1 - 0.012 15.0 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger Thioredoxin_7 PF13899.6 AAG04870.1 - 0.014 15.5 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like zf-C2H2_9 PF16293.5 AAG04870.1 - 0.052 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) CcmH PF03918.14 AAG04871.1 - 8.2e-57 190.5 0.0 9.8e-57 190.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein DUF3565 PF12088.8 AAG04871.1 - 0.0054 16.7 0.8 2.6 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3565) PEP-CTERM PF07589.11 AAG04871.1 - 0.49 10.6 11.5 0.44 10.7 3.0 2.2 2 0 0 2 2 2 0 PEP-CTERM motif TPR_2 PF07719.17 AAG04872.1 - 8.4e-09 34.9 0.5 0.0011 18.9 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAG04872.1 - 1.6e-06 28.7 20.6 0.00011 22.8 3.7 5.2 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 AAG04872.1 - 4e-05 24.0 12.2 0.013 16.0 0.7 4.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AAG04872.1 - 6.3e-05 22.6 0.0 0.054 13.3 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 AAG04872.1 - 9.3e-05 22.5 3.8 0.0024 18.0 2.5 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAG04872.1 - 0.0022 17.9 0.1 3 8.1 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAG04872.1 - 0.0022 18.6 1.6 0.0022 18.6 1.6 5.7 4 3 2 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAG04872.1 - 0.0033 17.7 4.0 1.9 8.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAG04872.1 - 0.024 15.0 0.3 9.5 6.9 0.0 3.8 3 1 0 3 3 2 0 Tetratricopeptide repeat Paf67 PF10255.9 AAG04872.1 - 0.076 12.0 0.0 8.6 5.2 0.0 2.1 1 1 1 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_8 PF13181.6 AAG04872.1 - 0.096 12.9 1.0 0.35 11.2 0.0 2.5 4 0 0 4 4 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAG04872.1 - 0.99 9.4 9.8 1.1 9.2 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat GerE PF00196.19 AAG04873.1 - 2.7e-15 55.7 0.0 4e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 AAG04873.1 - 0.0031 17.3 0.4 0.0074 16.0 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AAG04873.1 - 0.0046 17.0 0.2 0.012 15.7 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 AAG04873.1 - 0.0094 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4_2 PF08281.12 AAG04873.1 - 0.076 12.7 0.4 0.16 11.7 0.4 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 AAG04873.1 - 0.11 12.4 0.2 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain AA_permease_2 PF13520.6 AAG04874.1 - 4.3e-36 124.6 38.0 5.3e-36 124.4 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAG04874.1 - 7.5e-15 54.5 34.4 1e-14 54.0 34.4 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_S58 PF03576.14 AAG04875.1 - 2.8e-109 365.2 0.3 3.2e-109 365.1 0.3 1.0 1 0 0 1 1 1 1 Peptidase family S58 FGGY_N PF00370.21 AAG04876.1 - 2e-48 165.1 0.0 2.9e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AAG04876.1 - 6e-31 107.7 0.1 1.1e-30 106.8 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pyr_redox_2 PF07992.14 AAG04877.1 - 1.9e-18 66.8 0.0 2.4e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG04877.1 - 3.4e-13 49.5 6.3 4.3e-07 29.4 2.0 2.3 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 AAG04877.1 - 4.1e-10 39.8 4.1 2.2e-05 24.2 1.1 3.2 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG04877.1 - 1.5e-08 34.7 0.3 4.4e-06 26.8 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AAG04877.1 - 4.8e-08 32.6 0.0 1.9e-05 24.1 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG04877.1 - 8.6e-08 31.8 1.8 2.2e-07 30.5 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AAG04877.1 - 3e-07 29.5 0.8 0.0017 17.1 1.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 AAG04877.1 - 2.4e-06 27.2 0.3 4.2e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG04877.1 - 6.6e-05 22.3 0.3 0.00011 21.6 0.3 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 AAG04877.1 - 0.0017 18.4 1.4 0.4 10.7 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 AAG04877.1 - 0.0019 18.7 0.0 0.5 11.0 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAG04877.1 - 0.0072 15.7 2.3 0.014 14.7 1.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 AAG04877.1 - 0.031 13.3 2.2 0.055 12.5 0.8 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 AAG04877.1 - 0.069 12.2 0.5 0.1 11.7 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 AAG04877.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 AAG04877.1 - 0.27 10.0 0.2 0.49 9.2 0.2 1.4 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 AAG04878.1 - 2.3e-36 126.1 1.7 2.7e-36 125.9 1.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer2_BFD PF04324.15 AAG04878.1 - 2.6e-09 37.3 0.5 6.7e-09 36.0 0.5 1.7 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain DeoRC PF00455.22 AAG04879.1 - 1.9e-47 161.2 0.1 2.5e-47 160.8 0.1 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AAG04879.1 - 1.2e-17 63.3 0.2 2.7e-17 62.2 0.2 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAG04879.1 - 6.9e-09 35.5 1.7 1.3e-08 34.7 1.7 1.4 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 AAG04879.1 - 4.6e-07 29.6 0.8 8e-07 28.8 0.8 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAG04879.1 - 6.2e-07 29.4 2.5 1.4e-06 28.3 2.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 AAG04879.1 - 2.2e-05 24.3 1.0 4.7e-05 23.2 0.4 1.9 2 0 0 2 2 1 1 MarR family HTH_24 PF13412.6 AAG04879.1 - 2.7e-05 23.6 2.8 7.6e-05 22.2 1.4 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAG04879.1 - 0.00014 21.7 1.0 0.00038 20.3 0.2 2.1 2 0 0 2 2 2 1 MarR family FeoC PF09012.10 AAG04879.1 - 0.00023 21.2 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_Crp_2 PF13545.6 AAG04879.1 - 0.00037 20.4 0.7 0.00098 19.1 0.7 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 AAG04879.1 - 0.00062 19.4 1.4 0.0017 17.9 1.4 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AAG04879.1 - 0.00065 20.0 0.1 0.0019 18.5 0.1 1.8 1 0 0 1 1 1 1 Transcriptional regulator HTH_AsnC-type PF13404.6 AAG04879.1 - 0.0011 18.8 5.2 0.0012 18.6 3.1 2.3 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 AAG04879.1 - 0.0011 18.7 1.2 0.003 17.3 1.2 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Mga PF08280.11 AAG04879.1 - 0.0016 18.5 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_15 PF12324.8 AAG04879.1 - 0.0032 17.4 0.1 0.0068 16.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of alkylmercury lyase Put_DNA-bind_N PF06971.13 AAG04879.1 - 0.005 16.8 0.5 0.014 15.4 0.5 1.8 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus HTH_12 PF08461.10 AAG04879.1 - 0.02 14.8 0.1 0.05 13.6 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HemN_C PF06969.16 AAG04879.1 - 0.023 14.7 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 HemN C-terminal domain HTH_IclR PF09339.10 AAG04879.1 - 0.027 14.3 3.8 0.059 13.2 1.7 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain TFIIE_alpha PF02002.17 AAG04879.1 - 0.057 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit TrmB PF01978.19 AAG04879.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 AAG04879.1 - 0.065 13.4 0.4 0.21 11.8 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 AAG04879.1 - 0.084 13.5 3.4 0.23 12.1 3.4 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_31 PF13560.6 AAG04879.1 - 0.13 12.6 2.7 0.18 12.2 1.0 2.1 2 0 0 2 2 1 0 Helix-turn-helix domain DUF977 PF06163.11 AAG04879.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Sigma70_r4 PF04545.16 AAG04879.1 - 0.15 11.6 3.4 0.35 10.4 3.4 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 NADHdeh_related PF10125.9 AAG04879.1 - 0.2 11.0 0.5 3.6 6.9 0.1 2.1 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein HTH_38 PF13936.6 AAG04879.1 - 1.7 8.5 6.9 0.21 11.4 2.0 2.1 2 0 0 2 2 1 0 Helix-turn-helix domain EutH PF04346.12 AAG04880.1 - 9.3e-114 380.3 27.7 1.1e-113 380.1 27.7 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH LapA_dom PF06305.11 AAG04880.1 - 0.16 11.8 0.4 29 4.6 0.0 3.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF1937 PF09152.10 AAG04881.1 - 9e-49 165.1 0.1 1e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1937) SBP_bac_11 PF13531.6 AAG04882.1 - 5.3e-41 140.9 0.2 6.2e-41 140.6 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG04882.1 - 1.2e-09 38.0 0.2 1.8e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAG04882.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain DUF4139 PF13598.6 AAG04883.1 - 5.3e-65 219.0 0.0 7.5e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 AAG04883.1 - 9.1e-24 83.8 9.3 9.6e-23 80.5 3.0 2.8 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) Top6b_C PF18000.1 AAG04883.1 - 0.0068 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Type 2 DNA topoisomerase 6 subunit B C-terminal domain V_ATPase_I PF01496.19 AAG04883.1 - 0.03 12.3 0.5 0.039 11.9 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 AAG04883.1 - 0.055 12.8 6.9 0.091 12.1 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 AAG04883.1 - 0.076 13.5 8.6 0.31 11.6 8.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 AAG04883.1 - 0.13 12.8 2.7 0.28 11.7 0.4 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.11 AAG04883.1 - 0.26 11.9 14.1 0.52 10.9 5.5 2.7 2 0 0 2 2 2 0 MerR, DNA binding Spc24 PF08286.11 AAG04883.1 - 1.4 9.2 5.1 3 8.1 1.3 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 P120R PF08062.11 AAG04883.1 - 2 8.9 4.6 2.2 8.8 2.1 2.5 2 0 0 2 2 2 0 P120R (NUC006) repeat Ion_trans PF00520.31 AAG04885.1 - 1.1e-28 100.1 7.6 1.3e-28 99.9 7.6 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 AAG04885.1 - 2.4e-13 49.9 9.4 2.4e-13 49.9 9.4 2.4 2 1 0 2 2 2 1 Ion channel PKD_channel PF08016.12 AAG04885.1 - 0.045 12.4 4.1 0.035 12.8 2.9 1.4 1 1 0 1 1 1 0 Polycystin cation channel NOB1_Zn_bind PF08772.11 AAG04885.1 - 0.085 13.0 2.1 0.15 12.2 2.1 1.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like HlyIII PF03006.20 AAG04885.1 - 0.8 9.4 6.5 0.74 9.5 5.3 1.6 1 1 0 1 1 1 0 Haemolysin-III related DUF21 PF01595.20 AAG04885.1 - 1 9.0 7.8 0.24 11.1 2.4 2.3 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain UT PF03253.14 AAG04886.1 - 2.9e-50 171.0 26.1 3.8e-50 170.7 26.1 1.1 1 0 0 1 1 1 1 Urea transporter Peptidase_U4 PF03419.13 AAG04886.1 - 5.5 6.2 9.0 1.9 7.7 1.6 2.3 1 1 0 2 2 2 0 Sporulation factor SpoIIGA PK PF00224.21 AAG04887.1 - 5.4e-111 370.8 0.0 7e-111 370.5 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AAG04887.1 - 7.9e-28 97.0 0.7 2.2e-27 95.6 0.1 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 AAG04887.1 - 0.0072 15.4 0.6 0.37 9.7 0.0 2.5 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glyco_hydro_3_C PF01915.22 AAG04887.1 - 0.11 12.4 0.0 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain DUF4147 PF13660.6 AAG04888.1 - 2.5e-79 266.1 0.2 3.4e-79 265.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 AAG04888.1 - 1.3e-35 121.8 0.7 3.5e-35 120.5 0.6 1.8 2 0 0 2 2 2 1 MOFRL family NBD_C PF17042.5 AAG04888.1 - 0.0086 16.6 0.8 1 9.9 0.1 2.4 2 0 0 2 2 2 2 Nucleotide-binding C-terminal domain NAD_binding_2 PF03446.15 AAG04889.1 - 4.5e-50 169.9 0.5 7.6e-50 169.2 0.5 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAG04889.1 - 3.2e-36 124.2 0.5 5e-36 123.6 0.5 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AAG04889.1 - 2.3e-10 40.9 0.2 8.2e-09 35.9 0.1 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 AAG04889.1 - 3e-06 26.9 0.0 5.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 AAG04889.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 AAG04889.1 - 0.00032 20.5 0.1 0.00065 19.6 0.1 1.6 1 0 0 1 1 1 1 Rossmann-like domain 3HCDH_N PF02737.18 AAG04889.1 - 0.033 14.1 0.1 0.075 12.9 0.1 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAG04889.1 - 0.11 13.3 0.0 0.25 12.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AP_endonuc_2 PF01261.24 AAG04890.1 - 3.2e-34 118.2 0.5 4.1e-34 117.9 0.5 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TPP_enzyme_N PF02776.18 AAG04891.1 - 6e-54 182.2 0.8 2.5e-51 173.7 0.3 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG04891.1 - 2e-37 128.0 0.1 8.2e-37 126.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AAG04891.1 - 9.3e-35 119.7 0.1 3.7e-33 114.5 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2786 PF10979.8 AAG04891.1 - 0.012 15.5 1.6 0.015 15.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) CO_dh PF02552.16 AAG04891.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Haem_degrading PF03928.14 AAG04892.1 - 6.5e-27 94.0 0.7 7.3e-27 93.8 0.7 1.0 1 0 0 1 1 1 1 Haem-degrading TruB_C PF09142.11 AAG04892.1 - 0.0019 17.9 3.1 0.01 15.6 0.6 2.5 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal TetR_C_3 PF08362.11 AAG04893.1 - 7.8e-62 207.4 0.0 9.7e-62 207.1 0.0 1.1 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 AAG04893.1 - 6.2e-17 61.1 0.1 1.4e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 AAG04893.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain TetR_C_29 PF17938.1 AAG04893.1 - 0.066 13.3 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 AAG04893.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain Mob_synth_C PF06463.13 AAG04894.1 - 1.5e-38 131.7 0.0 3.5e-38 130.4 0.0 1.6 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AAG04894.1 - 1.6e-30 106.7 0.0 2.2e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAG04894.1 - 7.4e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAG04894.1 - 4.4e-05 23.6 0.0 9.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain LMWPc PF01451.21 AAG04895.1 - 2.2e-05 24.9 0.1 0.002 18.5 0.0 2.1 1 1 1 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase Xan_ur_permease PF00860.20 AAG04896.1 - 9e-100 334.1 44.7 1.1e-99 333.8 44.7 1.1 1 0 0 1 1 1 1 Permease family PAAR_motif PF05488.13 AAG04897.1 - 3e-21 75.3 2.9 3.5e-21 75.2 2.9 1.0 1 0 0 1 1 1 1 PAAR motif Zn-C2H2_12 PF18112.1 AAG04897.1 - 0.17 12.4 0.2 0.27 11.7 0.2 1.2 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Tli4_C PF18426.1 AAG04898.1 - 5.5e-42 143.8 0.0 8.9e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Tle cognate immunity protein 4 C-terminal domain Tli4_N PF18443.1 AAG04898.1 - 1.1e-09 38.8 0.0 1.6e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Tle cognate immunity protein 4 N-terminal domain PGAP1 PF07819.13 AAG04899.1 - 4.9e-06 26.4 0.0 0.0001 22.1 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 AAG04899.1 - 0.0037 17.9 1.4 0.014 16.0 1.3 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG04899.1 - 0.042 13.1 0.1 0.088 12.1 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Phage_GPD PF05954.11 AAG04900.1 - 3e-74 250.0 2.5 3e-74 250.0 2.5 1.5 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 AAG04900.1 - 5.4e-49 165.9 6.9 6.1e-49 165.8 6.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) T6SS_Vgr PF13296.6 AAG04900.1 - 2.7e-34 117.6 0.5 6.5e-34 116.3 0.5 1.7 1 0 0 1 1 1 1 Putative type VI secretion system Rhs element Vgr DUF4774 PF15999.5 AAG04900.1 - 5.9 6.8 7.5 0.62 9.9 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4774) T6SS_HCP PF05638.12 AAG04901.1 - 5.6e-37 127.0 0.1 6.4e-37 126.8 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp Urate_ox_N PF06181.11 AAG04902.1 - 1.8e-128 428.1 10.8 2.2e-128 427.8 10.8 1.1 1 0 0 1 1 1 1 Urate oxidase N-terminal Cytochrome-c551 PF10643.9 AAG04902.1 - 0.0034 17.0 2.9 0.013 15.1 2.9 2.0 1 1 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 DUF1129 PF06570.11 AAG04902.1 - 0.012 15.1 0.4 0.012 15.1 0.4 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) Haem_bd PF14376.6 AAG04902.1 - 0.028 14.3 0.1 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Haem-binding domain Ureidogly_lyase PF04115.12 AAG04903.1 - 2.7e-53 180.5 0.0 3.1e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Allantoicase PF03561.15 AAG04904.1 - 7.4e-97 321.1 0.0 4.9e-48 162.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat OHCU_decarbox PF09349.10 AAG04905.1 - 1.1e-45 155.9 1.5 1.2e-45 155.7 1.5 1.0 1 0 0 1 1 1 1 OHCU decarboxylase AnfG_VnfG PF03139.15 AAG04905.1 - 0.014 15.5 0.0 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit Polysacc_deac_1 PF01522.21 AAG04906.1 - 1.8e-17 63.4 0.0 3.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Ribosomal_L5 PF00281.19 AAG04906.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L5 DUF2334 PF10096.9 AAG04906.1 - 0.021 14.5 0.0 0.044 13.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Transthyretin PF00576.21 AAG04907.1 - 1.7e-35 122.0 0.0 1.9e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 AAG04907.1 - 0.055 13.7 0.0 0.088 13.1 0.0 1.4 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Xan_ur_permease PF00860.20 AAG04908.1 - 1.9e-50 171.7 45.4 2.5e-50 171.3 45.4 1.2 1 0 0 1 1 1 1 Permease family FCD PF07729.12 AAG04909.1 - 5.7e-23 81.7 4.9 5.7e-23 81.7 4.9 1.9 2 1 0 2 2 2 1 FCD domain GntR PF00392.21 AAG04909.1 - 1.7e-17 62.8 3.7 4.6e-17 61.4 0.3 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AAG04909.1 - 0.00061 19.7 1.0 0.0044 16.9 0.1 2.4 2 1 1 3 3 3 1 HTH domain HTH_Crp_2 PF13545.6 AAG04909.1 - 0.0013 18.6 0.9 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 AAG04909.1 - 0.0027 17.4 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Reductase_C PF14759.6 AAG04909.1 - 0.03 14.9 0.2 0.066 13.8 0.2 1.6 1 0 0 1 1 1 0 Reductase C-terminal Amidohydro_1 PF01979.20 AAG04910.1 - 5.4e-69 233.1 0.0 6.2e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG04910.1 - 6.1e-11 42.5 0.5 1.7e-06 27.8 0.0 2.8 1 1 1 2 2 2 2 Amidohydrolase family XdhC_C PF13478.6 AAG04911.1 - 6.9e-38 130.0 0.0 1.2e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AAG04911.1 - 1.1e-18 67.1 0.1 4.2e-18 65.3 0.2 2.0 2 0 0 2 2 2 1 XdhC and CoxI family TrkA_N PF02254.18 AAG04911.1 - 0.028 14.7 0.0 0.085 13.1 0.0 1.8 2 1 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAG04911.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAG04911.1 - 0.2 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ald_Xan_dh_C2 PF02738.18 AAG04912.1 - 1.3e-210 700.5 1.3 1.7e-210 700.2 1.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAG04912.1 - 2.7e-22 79.2 0.1 5.9e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain DHHA1 PF02272.19 AAG04912.1 - 0.27 11.6 1.2 2.3 8.6 0.0 2.8 3 0 0 3 3 3 0 DHHA1 domain FAD_binding_5 PF00941.21 AAG04913.1 - 8.8e-51 172.0 0.0 1.7e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAG04913.1 - 1.8e-30 105.2 2.2 3.6e-30 104.2 2.2 1.5 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 AAG04913.1 - 2.1e-30 104.6 0.4 4.6e-30 103.5 0.4 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAG04913.1 - 4e-07 29.9 4.4 6.4e-06 26.0 0.3 2.6 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAG04913.1 - 0.3 11.1 2.6 0.53 10.3 0.2 2.7 2 1 1 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain FA_desaturase PF00487.24 AAG04914.1 - 1.3e-26 94.0 20.0 1.3e-26 94.0 20.0 3.0 3 0 0 3 3 3 1 Fatty acid desaturase Glucos_trans_II PF14264.6 AAG04914.1 - 0.073 12.4 0.1 0.073 12.4 0.1 2.1 2 0 0 2 2 2 0 Glucosyl transferase GtrII GntR PF00392.21 AAG04915.1 - 7.3e-13 48.0 4.2 1.5e-12 47.0 4.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AAG04915.1 - 2e-09 37.9 2.6 2e-09 37.9 2.6 1.7 2 0 0 2 2 2 1 FCD domain HOIP-UBA PF16678.5 AAG04915.1 - 0.025 14.6 0.4 0.054 13.5 0.1 1.7 2 0 0 2 2 2 0 HOIP UBA domain pair Fe_dep_repress PF01325.19 AAG04915.1 - 0.035 14.3 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain SMC_N PF02463.19 AAG04916.1 - 3.2e-68 229.5 0.0 5.1e-68 228.8 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG04916.1 - 1.7e-17 64.6 0.3 1.7e-17 64.6 0.3 6.2 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.6 AAG04916.1 - 2.9e-16 60.2 0.8 2.6e-08 34.1 0.2 3.2 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAG04916.1 - 6.3e-13 49.2 0.0 5.3e-09 36.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AAG04916.1 - 2.5e-05 23.9 0.0 5.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 AAG04916.1 - 2.8e-05 24.4 0.0 0.00044 20.5 0.0 2.6 1 1 0 1 1 1 1 SMC proteins Flexible Hinge Domain ZipA_C PF04354.13 AAG04917.1 - 2.9e-49 166.2 0.1 5.1e-49 165.4 0.1 1.4 1 0 0 1 1 1 1 ZipA, C-terminal FtsZ-binding domain DNA_ligase_aden PF01653.18 AAG04918.1 - 3.7e-125 417.2 0.0 5.7e-125 416.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 AAG04918.1 - 1.1e-35 121.3 2.1 3.3e-35 119.8 1.9 1.9 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 AAG04918.1 - 2.2e-33 114.1 0.4 3.3e-21 75.1 0.0 3.6 4 0 0 4 4 4 2 Helix-hairpin-helix motif DNA_ligase_ZBD PF03119.16 AAG04918.1 - 5.6e-14 51.9 1.3 1.4e-13 50.6 1.3 1.8 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain BRCT PF00533.26 AAG04918.1 - 5.4e-12 45.9 0.0 9.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 AAG04918.1 - 1e-09 38.8 0.4 0.085 13.5 0.0 4.3 4 0 0 4 4 4 3 Helix-hairpin-helix domain HHH PF00633.23 AAG04918.1 - 0.0043 16.9 1.0 12 5.9 0.0 4.3 4 0 0 4 4 4 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AAG04918.1 - 0.0059 17.2 0.0 1.9 9.1 0.0 2.6 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold PTCB-BRCT PF12738.7 AAG04918.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain DUF2116 PF09889.9 AAG04918.1 - 0.53 10.3 1.4 0.65 10.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SBP_bac_3 PF00497.20 AAG04920.1 - 3.3e-11 43.1 0.0 7e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DNA_pol3_delta2 PF13177.6 AAG04921.1 - 1.8e-44 151.4 0.0 2.6e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 AAG04921.1 - 7.6e-34 116.7 0.3 2.3e-33 115.1 0.3 1.8 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III DNA_pol3_tau_5 PF12170.8 AAG04921.1 - 3.3e-16 59.6 0.0 5.6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III tau subunit V interacting with alpha AAA PF00004.29 AAG04921.1 - 8.5e-11 42.4 0.0 2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAG04921.1 - 2.5e-07 30.6 0.0 5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AAG04921.1 - 4.9e-06 26.6 0.1 4.9e-05 23.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 AAG04921.1 - 8.5e-05 22.6 0.1 0.41 10.6 0.0 2.2 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.6 AAG04921.1 - 0.00014 22.4 0.0 0.00036 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG04921.1 - 0.0002 21.6 0.1 0.0011 19.3 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 AAG04921.1 - 0.00033 21.1 3.2 0.0015 18.9 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 AAG04921.1 - 0.00046 20.0 0.0 0.0016 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AAG04921.1 - 0.0007 19.6 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 AAG04921.1 - 0.0015 17.8 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_24 PF13479.6 AAG04921.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAG04921.1 - 0.0093 16.3 0.1 0.13 12.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF3646 PF12362.8 AAG04921.1 - 0.013 15.8 0.3 0.013 15.8 0.3 2.1 3 0 0 3 3 1 0 DNA polymerase III gamma and tau subunits C terminal TsaE PF02367.17 AAG04921.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 AAG04921.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Rad17 PF03215.15 AAG04921.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 AAG04921.1 - 0.029 13.9 0.0 0.32 10.5 0.0 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 AAG04921.1 - 0.041 13.3 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein SKI PF01202.22 AAG04921.1 - 0.051 13.7 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 1 0 Shikimate kinase AAA_assoc_2 PF16193.5 AAG04921.1 - 0.084 13.2 0.7 3.2 8.1 0.0 2.7 1 1 1 2 2 2 0 AAA C-terminal domain Herpes_Helicase PF02689.14 AAG04921.1 - 0.11 10.4 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Helicase Mg_chelatase PF01078.21 AAG04921.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-CXXC PF02008.20 AAG04921.1 - 0.16 12.1 3.0 0.27 11.3 3.0 1.2 1 0 0 1 1 1 0 CXXC zinc finger domain RsgA_GTPase PF03193.16 AAG04921.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase YbaB_DNA_bd PF02575.16 AAG04922.1 - 9.5e-35 118.7 12.0 1.1e-34 118.5 12.0 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Hemocyanin_C PF03723.14 AAG04922.1 - 0.036 13.4 0.2 0.052 12.9 0.0 1.3 2 0 0 2 2 2 0 Hemocyanin, ig-like domain Rnk_N PF14760.6 AAG04922.1 - 0.043 14.3 1.4 6.8 7.3 0.2 2.2 2 0 0 2 2 2 0 Rnk N-terminus Hexokinase_1 PF00349.21 AAG04922.1 - 0.11 12.4 0.7 0.39 10.6 0.7 1.8 1 1 0 1 1 1 0 Hexokinase DUF2294 PF10057.9 AAG04922.1 - 0.18 11.9 2.0 0.8 9.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF3947 PF13135.6 AAG04922.1 - 9 6.6 7.7 3.4 7.9 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Toprim_4 PF13662.6 AAG04923.1 - 1.5e-24 86.2 0.0 2.9e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 AAG04923.1 - 1.3e-16 59.8 0.4 2.6e-16 58.9 0.4 1.5 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 AAG04923.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAG04923.1 - 0.049 14.1 0.0 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Toprim-like HHH_5 PF14520.6 AAG04923.1 - 0.11 13.2 0.0 0.34 11.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Acyl-CoA_dh_1 PF00441.24 AAG04924.1 - 1.9e-46 158.0 5.9 3e-46 157.3 5.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG04924.1 - 3.9e-27 95.2 1.4 8.8e-27 94.0 0.1 2.3 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG04924.1 - 2.8e-24 85.1 0.1 5.1e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG04924.1 - 3.4e-15 56.5 1.8 5.7e-15 55.8 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3543 PF12063.8 AAG04924.1 - 0.043 13.2 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) UPF0167 PF03691.14 AAG04925.1 - 1.8e-61 207.0 0.1 2e-61 206.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0167) Zn-ribbon_8 PF09723.10 AAG04925.1 - 0.77 9.9 7.9 7.3 6.8 0.3 3.1 3 0 0 3 3 3 0 Zinc ribbon domain adh_short PF00106.25 AAG04926.1 - 2.1e-51 174.1 1.9 2.7e-51 173.8 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG04926.1 - 7.7e-38 130.4 2.3 1e-37 129.9 2.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG04926.1 - 1.1e-13 51.5 1.4 1.9e-13 50.7 1.4 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 AAG04926.1 - 0.021 15.5 0.1 0.052 14.2 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AAG04926.1 - 0.026 14.1 0.5 0.29 10.6 0.2 2.2 2 0 0 2 2 2 0 Methyltransferase small domain PE PF00934.20 AAG04926.1 - 0.13 12.6 3.4 0.38 11.1 3.4 1.8 1 0 0 1 1 1 0 PE family FMO-like PF00743.19 AAG04927.1 - 3.1e-15 55.6 0.0 1.8e-12 46.5 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 AAG04927.1 - 3.4e-12 46.2 0.0 1.4e-11 44.2 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAG04927.1 - 1.7e-11 43.9 0.0 2.3e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG04927.1 - 6.7e-11 42.3 0.0 6.7e-11 42.3 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 AAG04927.1 - 1.6e-10 40.7 0.2 2e-07 30.5 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 AAG04927.1 - 0.00012 21.8 0.0 0.00043 20.0 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AAG04927.1 - 0.00087 19.3 1.1 0.028 14.4 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 AAG04927.1 - 0.011 14.9 0.2 0.032 13.3 0.2 1.7 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 AAG04927.1 - 0.029 14.9 0.0 1.4 9.5 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG04927.1 - 0.036 12.8 0.0 2.6 6.6 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein TetR_N PF00440.23 AAG04928.1 - 3.1e-07 30.1 0.0 9.2e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1 PF01527.20 AAG04928.1 - 0.018 15.4 0.3 0.055 13.8 0.0 2.0 2 0 0 2 2 2 0 Transposase HTH_AraC PF00165.23 AAG04928.1 - 0.074 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Multi_Drug_Res PF00893.19 AAG04929.1 - 1.3e-26 93.1 5.9 1.6e-26 92.8 5.9 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAG04929.1 - 8.7e-05 22.7 9.5 0.00011 22.3 9.5 1.3 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 AAG04929.1 - 0.00038 20.5 0.0 0.00057 19.9 0.0 1.3 1 1 0 1 1 1 1 Putative transmembrane family 234 UPF0060 PF02694.15 AAG04929.1 - 0.14 12.4 7.4 0.078 13.2 5.3 1.5 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Multi_Drug_Res PF00893.19 AAG04930.1 - 1.8e-23 83.0 10.3 2.5e-23 82.5 10.3 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAG04930.1 - 0.00043 20.5 12.5 0.00082 19.5 12.4 1.6 1 1 0 1 1 1 1 EamA-like transporter family UPF0060 PF02694.15 AAG04930.1 - 1.2 9.4 10.0 1.4 9.2 10.0 1.1 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family Metal_hydrol PF10118.9 AAG04931.1 - 4.7e-91 304.9 0.8 5.4e-91 304.7 0.8 1.0 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase Pribosyltran PF00156.27 AAG04932.1 - 1.2e-12 47.7 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAG04932.1 - 0.018 14.5 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Crp PF00325.20 AAG04933.1 - 1.9e-17 62.6 0.0 4.1e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family cNMP_binding PF00027.29 AAG04933.1 - 7.4e-17 61.2 0.0 1.4e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAG04933.1 - 1.5e-16 60.1 0.1 3.8e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AAG04933.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 AAG04933.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.8 1 1 1 2 2 2 0 Homeodomain-like domain FapA PF03961.13 AAG04934.1 - 0.0018 17.0 0.8 0.0019 16.9 0.8 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 AAG04934.1 - 0.0019 18.4 4.8 0.0019 18.4 4.8 2.0 2 0 0 2 2 2 1 ABC transporter C-terminal domain ApoLp-III PF07464.11 AAG04934.1 - 0.0033 17.5 0.9 0.006 16.7 0.9 1.5 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) TBCC_N PF16752.5 AAG04934.1 - 0.0062 17.0 1.4 0.0083 16.6 1.4 1.4 1 1 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Syntaxin_2 PF14523.6 AAG04934.1 - 0.0069 16.7 0.3 0.0087 16.4 0.3 1.2 1 0 0 1 1 1 1 Syntaxin-like protein GHL13 PF14883.6 AAG04934.1 - 0.018 14.1 0.4 0.022 13.8 0.4 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 DUF4795 PF16043.5 AAG04934.1 - 0.018 14.6 3.9 0.022 14.4 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF713 PF05218.14 AAG04934.1 - 0.02 14.7 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Spc7 PF08317.11 AAG04934.1 - 0.026 13.4 4.4 0.031 13.2 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2203 PF09969.9 AAG04934.1 - 0.028 15.1 1.6 0.028 15.1 1.6 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YkyA PF10368.9 AAG04934.1 - 0.029 14.0 3.7 0.035 13.8 3.7 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF5398 PF17376.2 AAG04934.1 - 0.062 13.9 3.3 0.1 13.2 1.6 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5398) ING PF12998.7 AAG04934.1 - 0.078 13.6 1.4 0.13 12.8 1.4 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding LUC7 PF03194.15 AAG04934.1 - 0.093 12.4 1.6 0.13 11.9 1.6 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Latarcin PF10279.9 AAG04934.1 - 0.11 12.9 1.0 0.18 12.3 1.0 1.3 1 0 0 1 1 1 0 Latarcin precursor Seryl_tRNA_N PF02403.22 AAG04934.1 - 0.12 12.6 6.1 0.041 14.1 3.5 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 AAG04934.1 - 0.16 12.3 8.5 0.11 12.9 7.0 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) 5_nucleotid PF05761.14 AAG04934.1 - 0.22 10.4 0.5 0.26 10.1 0.5 1.1 1 0 0 1 1 1 0 5' nucleotidase family AAA_23 PF13476.6 AAG04934.1 - 0.22 12.0 1.0 0.26 11.8 1.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.6 AAG04934.1 - 0.23 11.9 8.1 32 5.0 8.1 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.12 AAG04934.1 - 0.26 11.7 6.5 2.8 8.4 4.7 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 AAG04934.1 - 0.29 10.3 0.5 0.33 10.2 0.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein T3SS_needle_F PF09392.10 AAG04934.1 - 0.35 11.1 6.1 1.7 8.9 0.3 2.8 2 1 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Nas2_N PF18265.1 AAG04934.1 - 0.36 10.8 3.2 5 7.1 0.4 2.2 1 1 1 2 2 2 0 Nas2 N_terminal domain BST2 PF16716.5 AAG04934.1 - 0.38 11.4 6.6 0.44 11.2 0.3 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 COMP PF11598.8 AAG04934.1 - 0.6 10.6 5.5 14 6.3 1.7 2.4 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein FUSC PF04632.12 AAG04934.1 - 0.62 8.5 6.7 0.77 8.2 6.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GARP PF16731.5 AAG04934.1 - 0.93 9.1 14.0 0.33 10.6 5.9 2.1 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF4407 PF14362.6 AAG04934.1 - 1.4 8.2 8.7 2.4 7.4 8.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PKcGMP_CC PF16808.5 AAG04934.1 - 3.3 7.7 10.7 24 4.9 0.0 3.0 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Radical_SAM PF04055.21 AAG04935.1 - 1.9e-18 67.4 0.0 3.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AAG04935.1 - 3e-12 46.4 2.1 5.4e-12 45.6 0.1 2.4 3 0 0 3 3 3 1 HemN C-terminal domain DsbD_2 PF13386.6 AAG04936.1 - 1.2e-55 188.6 25.8 1.3e-55 188.4 25.8 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD PF02683.15 AAG04936.1 - 7e-06 26.1 15.7 1.8e-05 24.7 8.9 2.4 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region Wzy_C_2 PF11846.8 AAG04936.1 - 7.8 6.4 6.6 0.85 9.5 0.5 2.2 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal FixS PF03597.15 AAG04937.1 - 9.2e-22 76.5 4.0 1.2e-21 76.1 4.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase maturation protein cbb3-type DUF4448 PF14610.6 AAG04937.1 - 0.39 10.5 3.2 0.51 10.1 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Promethin PF16015.5 AAG04937.1 - 0.41 10.6 3.3 0.5 10.3 3.3 1.1 1 0 0 1 1 1 0 Promethin E1-E2_ATPase PF00122.20 AAG04938.1 - 2.7e-48 163.9 0.0 5.1e-48 163.0 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAG04938.1 - 4.9e-33 115.2 0.0 9.6e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATPase-cat_bd PF12156.8 AAG04938.1 - 3.7e-28 98.1 0.0 5.8e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase HMA PF00403.26 AAG04938.1 - 5.2e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AAG04938.1 - 2.1e-08 34.2 0.0 3.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG04938.1 - 1.9e-06 28.4 0.1 6.7e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CcmB PF03379.13 AAG04938.1 - 0.26 10.8 8.0 0.06 12.8 4.0 1.9 2 0 0 2 2 2 0 CcmB protein FixH PF05751.11 AAG04939.1 - 2.1e-39 134.9 0.0 2.4e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 FixH SCIMP PF15050.6 AAG04939.1 - 0.051 14.0 0.1 0.073 13.5 0.1 1.3 1 0 0 1 1 1 0 SCIMP protein P_proprotein PF01483.20 AAG04939.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain Innexin PF00876.18 AAG04939.1 - 0.18 11.0 0.1 0.24 10.6 0.1 1.1 1 0 0 1 1 1 0 Innexin Fer4_18 PF13746.6 AAG04940.1 - 6.9e-46 155.1 7.1 1.3e-45 154.3 7.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain FixG_C PF11614.8 AAG04940.1 - 7.6e-27 93.9 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fer4_7 PF12838.7 AAG04940.1 - 4.8e-09 36.7 9.4 2.4e-05 24.9 1.2 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG04940.1 - 2.1e-08 34.6 10.4 0.0001 22.8 1.1 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG04940.1 - 4.2e-08 33.2 8.9 3.4e-05 23.9 0.9 3.1 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG04940.1 - 3.6e-07 30.5 8.8 5.3e-05 23.6 0.9 2.6 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG04940.1 - 6.4e-06 27.0 5.9 0.0012 19.7 0.8 2.8 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_5 PF12801.7 AAG04940.1 - 1.1e-05 25.2 11.1 1.1e-05 25.2 11.1 4.2 6 0 0 6 6 5 1 4Fe-4S binding domain Fer4_10 PF13237.6 AAG04940.1 - 1.4e-05 25.1 10.6 0.001 19.1 1.5 2.8 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAG04940.1 - 0.0013 18.8 14.5 0.2 11.8 5.5 3.2 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAG04940.1 - 0.0044 16.8 4.1 0.0044 16.8 4.1 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_13 PF13370.6 AAG04940.1 - 0.018 15.6 11.4 0.27 11.8 1.6 2.8 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_2 PF12797.7 AAG04940.1 - 2 8.7 21.9 0.16 12.2 3.3 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 AAG04940.1 - 2 9.2 11.2 3.8 8.3 2.0 2.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 AAG04940.1 - 5.2 8.2 27.1 0.25 12.3 4.8 3.7 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAG04940.1 - 6.1 7.1 26.3 0.093 12.8 5.6 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Cytochrome_CBB3 PF13442.6 AAG04941.1 - 2.8e-27 94.8 3.6 6e-14 52.1 0.1 2.6 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III FixP_N PF14715.6 AAG04941.1 - 1.9e-23 81.9 2.1 5.3e-23 80.5 2.1 1.8 1 0 0 1 1 1 1 N-terminal domain of cytochrome oxidase-cbb3, FixP Cytochrom_C PF00034.21 AAG04941.1 - 2.8e-16 60.4 4.9 2e-07 32.1 1.1 4.2 3 2 0 3 3 3 2 Cytochrome c Cytochrom_C550 PF14495.6 AAG04941.1 - 6.4e-06 25.9 0.8 0.26 11.0 0.1 3.6 3 1 1 4 4 4 2 Cytochrome c-550 domain PsaA_PsaB PF00223.19 AAG04941.1 - 0.014 13.6 0.0 0.023 12.9 0.0 1.2 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Paired_CXXCH_1 PF09699.10 AAG04941.1 - 0.033 13.9 0.4 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) PSCyt1 PF07635.11 AAG04941.1 - 0.082 13.5 0.1 15 6.2 0.0 2.7 2 0 0 2 2 2 0 Planctomycete cytochrome C Cytochrome_C7 PF14522.6 AAG04941.1 - 0.11 12.5 0.0 6.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c FixO PF02433.15 AAG04942.1 - 1.1e-86 289.8 0.0 2.6e-83 278.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome C oxidase, mono-heme subunit/FixO Cytochrom_C PF00034.21 AAG04942.1 - 6.6e-05 24.0 0.0 0.00018 22.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome c EPSP_synthase PF00275.20 AAG04942.1 - 0.065 11.9 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF2860 PF11059.8 AAG04942.1 - 0.25 10.5 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2860) COX1 PF00115.20 AAG04943.1 - 3.1e-115 385.5 62.7 4.2e-115 385.0 62.7 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrome_CBB3 PF13442.6 AAG04944.1 - 1.2e-26 92.8 1.4 2e-12 47.3 0.1 2.3 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III FixP_N PF14715.6 AAG04944.1 - 2.6e-23 81.5 2.7 2.6e-23 81.5 2.7 1.7 2 0 0 2 2 2 1 N-terminal domain of cytochrome oxidase-cbb3, FixP Cytochrom_C PF00034.21 AAG04944.1 - 7.2e-17 62.3 1.2 2.4e-07 31.8 0.4 4.0 2 2 0 2 2 2 2 Cytochrome c Cytochrom_C550 PF14495.6 AAG04944.1 - 0.00016 21.4 0.4 0.18 11.5 0.1 2.9 2 1 0 2 2 2 2 Cytochrome c-550 domain Cytochrome_C7 PF14522.6 AAG04944.1 - 0.07 13.1 0.0 7.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c PSCyt1 PF07635.11 AAG04944.1 - 0.86 10.2 3.1 17 6.1 0.1 2.9 3 1 0 3 3 3 0 Planctomycete cytochrome C FixO PF02433.15 AAG04945.1 - 4.2e-88 294.4 0.0 5.5e-84 281.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome C oxidase, mono-heme subunit/FixO Cytochrom_C PF00034.21 AAG04945.1 - 6.8e-06 27.1 0.0 1.8e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome c COX1 PF00115.20 AAG04946.1 - 5.4e-116 388.0 59.8 6.6e-116 387.7 59.8 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Hydrolase_4 PF12146.8 AAG04947.1 - 1.8e-07 30.7 0.0 0.00033 20.0 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAG04947.1 - 7.7e-07 29.9 4.8 1.8e-05 25.4 0.1 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF2048 PF09752.9 AAG04947.1 - 0.0094 15.1 0.4 0.02 14.0 0.2 1.6 1 1 1 2 2 2 1 Abhydrolase domain containing 18 DLH PF01738.18 AAG04947.1 - 0.011 15.3 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 AAG04947.1 - 0.023 14.6 0.1 0.35 10.7 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 AAG04947.1 - 0.077 12.6 0.0 0.27 10.8 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 AAG04947.1 - 0.22 11.3 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_4 PF07993.12 AAG04948.1 - 2.3e-25 89.2 0.0 3e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 AAG04948.1 - 2.6e-13 50.0 0.0 3.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAG04948.1 - 1.5e-06 27.9 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAG04948.1 - 0.00052 19.1 0.0 0.0014 17.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAG04948.1 - 0.00065 19.6 0.1 0.016 15.1 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAG04948.1 - 0.008 15.8 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 AAG04948.1 - 0.041 13.8 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 AAG04948.1 - 0.22 10.6 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MCPsignal PF00015.21 AAG04950.1 - 1.5e-48 164.8 35.4 6.4e-47 159.6 23.3 2.4 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AAG04950.1 - 1e-15 57.8 0.0 2.2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG04950.1 - 1.9e-10 40.9 0.0 6e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAG04950.1 - 5.5e-09 36.0 0.0 1.7e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAG04950.1 - 0.0012 19.1 0.9 0.0054 17.0 0.0 2.5 3 0 0 3 3 2 1 PAS fold LMBR1 PF04791.16 AAG04950.1 - 0.015 14.3 5.1 0.64 8.9 0.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF2530 PF10745.9 AAG04950.1 - 0.063 13.5 0.9 0.18 12.1 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) PAS_8 PF13188.7 AAG04950.1 - 0.076 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain DUF948 PF06103.11 AAG04950.1 - 0.36 11.1 24.1 0.75 10.1 1.9 4.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 AAG04950.1 - 1 9.8 16.8 0.44 10.9 1.1 4.2 2 2 0 3 3 3 0 Syntaxin-like protein Tweety PF04906.13 AAG04950.1 - 2.1 6.9 8.9 1 8.0 3.6 2.2 2 0 0 2 2 2 0 Tweety ISG65-75 PF11727.8 AAG04950.1 - 3.7 6.7 22.3 0.57 9.4 5.5 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein ATG_C PF09333.11 AAG04950.1 - 4 7.9 7.8 1.9 8.9 0.2 3.3 2 2 0 2 2 2 0 Autophagy-related protein C terminal domain CENP-F_leu_zip PF10473.9 AAG04950.1 - 5.8 6.9 12.3 1.5 8.9 1.7 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 AAG04950.1 - 6.5 6.9 16.0 9.3 6.4 3.8 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GIDA_assoc PF13932.6 AAG04950.1 - 8 6.6 10.6 4.8 7.3 1.9 2.3 2 0 0 2 2 2 0 GidA associated domain Aconitase PF00330.20 AAG04951.1 - 6.2e-184 612.3 0.0 8.3e-184 611.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AAG04951.1 - 1.5e-48 164.4 0.0 2.9e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RlmM_FDX PF18125.1 AAG04952.1 - 2.8e-23 82.2 0.0 6.7e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 RlmM ferredoxin-like domain FtsJ PF01728.19 AAG04952.1 - 1.2e-08 35.2 0.0 2.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase TusA PF01206.17 AAG04953.1 - 3.4e-24 84.4 0.0 3.8e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AAG04953.1 - 0.024 14.5 0.1 0.045 13.6 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) DAO PF01266.24 AAG04954.1 - 4.4e-51 174.5 5.0 5.2e-51 174.3 5.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAG04954.1 - 4.6e-08 32.8 1.0 1.5e-07 31.1 1.6 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG04954.1 - 3e-06 27.3 0.8 8.7e-06 25.9 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG04954.1 - 5.7e-06 25.8 0.1 9.6e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG04954.1 - 0.00047 19.5 1.0 0.001 18.4 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AAG04954.1 - 0.00047 19.5 0.6 0.00082 18.7 0.6 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 AAG04954.1 - 0.00062 18.9 0.9 0.0011 18.2 0.9 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AAG04954.1 - 0.00094 18.4 5.6 0.0015 17.7 5.5 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAG04954.1 - 0.0011 19.5 1.1 0.0027 18.2 1.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG04954.1 - 0.0084 14.9 0.5 0.013 14.2 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 AAG04954.1 - 0.014 15.4 0.2 0.029 14.4 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 AAG04954.1 - 0.014 14.6 0.3 0.12 11.5 0.5 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG04954.1 - 0.033 13.8 0.4 0.05 13.2 0.4 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AAG04954.1 - 0.13 12.2 0.9 0.21 11.5 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AAG04954.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Gln-synt_C PF00120.24 AAG04955.1 - 4.5e-107 358.0 0.0 5.2e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 AAG04955.1 - 0.053 13.3 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain DAO PF01266.24 AAG04956.1 - 1.4e-50 172.8 0.7 1.7e-50 172.6 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG04956.1 - 8.6e-06 25.9 0.3 2.5e-05 24.4 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAG04956.1 - 0.00014 21.2 0.5 0.00038 19.8 0.7 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 AAG04956.1 - 0.0024 17.2 0.1 0.0041 16.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG04956.1 - 0.0026 17.1 0.5 0.0045 16.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 AAG04956.1 - 0.012 14.5 0.2 0.028 13.3 0.2 1.7 1 1 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 AAG04956.1 - 0.019 14.0 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 AAG04956.1 - 0.048 13.2 0.2 0.072 12.7 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 AAG04956.1 - 0.38 9.8 4.9 0.38 9.8 1.1 2.0 2 0 0 2 2 2 0 FAD binding domain Ribonuc_L-PSP PF01042.21 AAG04957.1 - 1.9e-21 76.3 0.0 2.1e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 AAG04958.1 - 8.7e-41 140.0 49.5 2.8e-31 108.7 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5400 PF17379.2 AAG04958.1 - 1 9.9 5.5 1.6 9.3 0.9 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5400) LysR_substrate PF03466.20 AAG04959.1 - 5e-37 127.3 5.6 6.7e-37 126.9 5.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG04959.1 - 1.6e-21 76.0 0.5 5e-21 74.4 0.4 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAG04959.1 - 0.0039 16.3 0.0 0.0076 15.4 0.0 1.4 1 1 0 1 1 1 1 PBP superfamily domain MarR_2 PF12802.7 AAG04959.1 - 0.019 14.8 0.4 0.081 12.8 0.1 2.2 2 0 0 2 2 2 0 MarR family PBP_like_2 PF12849.7 AAG04959.1 - 0.046 13.4 0.0 5 6.7 0.0 2.1 2 0 0 2 2 2 0 PBP superfamily domain HTH_24 PF13412.6 AAG04959.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding NAD_kinase PF01513.21 AAG04961.1 - 5e-68 229.4 0.0 5.5e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AAG04961.1 - 5.9e-05 22.7 0.6 0.00015 21.4 0.2 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF1287 PF06940.11 AAG04962.1 - 7.1e-66 220.9 0.0 8.1e-66 220.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1287) Ppnp PF06865.11 AAG04963.1 - 4.1e-37 126.5 0.1 4.5e-37 126.3 0.1 1.0 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase Cupin_3 PF05899.12 AAG04963.1 - 0.0088 15.7 0.0 0.014 15.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 AAG04963.1 - 0.044 14.0 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_2 PF07883.11 AAG04963.1 - 0.065 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Cupin domain Beta-prism_lec PF16458.5 AAG04963.1 - 0.093 12.7 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Beta-prism lectin RNase_T PF00929.24 AAG04964.1 - 5.4e-19 69.3 0.0 2.4e-18 67.2 0.0 1.8 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAG04964.1 - 1.7e-08 34.6 0.2 3.9e-08 33.4 0.2 1.6 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like NAD_binding_2 PF03446.15 AAG04965.1 - 1.9e-44 151.6 0.0 2.8e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAG04965.1 - 1.1e-34 119.3 0.4 1.6e-34 118.7 0.4 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AAG04965.1 - 3.7e-07 30.7 0.0 7.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AAG04965.1 - 0.00023 21.2 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AAG04965.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAG04965.1 - 0.0034 17.3 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AAG04965.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 AAG04965.1 - 0.066 13.7 0.1 0.94 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 AAG04965.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DMT_6 PF04342.12 AAG04966.1 - 9.6e-47 157.5 5.5 1.1e-46 157.4 5.5 1.0 1 0 0 1 1 1 1 Putative member of DMT superfamily (DUF486) DUF1772 PF08592.11 AAG04966.1 - 0.81 10.0 8.0 0.089 13.1 1.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) START PF01852.19 AAG04968.1 - 4.4e-15 55.7 0.0 5.3e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 START domain Polyketide_cyc2 PF10604.9 AAG04968.1 - 3.3e-05 24.2 1.5 0.00011 22.5 0.9 2.0 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AAG04968.1 - 0.00019 21.7 0.0 0.00027 21.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Citrate_synt PF00285.21 AAG04969.1 - 5.6e-134 446.8 0.0 6.6e-134 446.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sdh_cyt PF01127.22 AAG04970.1 - 3.4e-32 111.0 1.5 3.9e-32 110.8 1.5 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AAG04970.1 - 0.0017 18.5 2.2 0.0023 18.0 2.2 1.3 1 0 0 1 1 1 1 Fumarate reductase subunit D Sdh_cyt PF01127.22 AAG04971.1 - 2.7e-07 30.7 15.7 9.7e-07 28.8 14.3 1.9 1 1 1 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_C PF02300.17 AAG04971.1 - 0.032 14.3 5.9 0.043 13.9 5.9 1.4 1 1 0 1 1 1 0 Fumarate reductase subunit C TcA_TcB_BD PF18276.1 AAG04971.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain CybS PF05328.12 AAG04971.1 - 0.12 12.1 2.7 0.43 10.3 2.7 1.9 1 1 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit PIG-P PF08510.12 AAG04971.1 - 2.9 7.8 7.4 1.2 9.0 5.3 1.5 1 1 0 1 1 1 0 PIG-P FAD_binding_2 PF00890.24 AAG04972.1 - 3.8e-118 395.2 10.5 4.7e-118 394.9 10.5 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAG04972.1 - 5e-41 139.7 0.3 7.7e-41 139.1 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AAG04972.1 - 7.4e-07 28.7 5.8 2.4e-05 23.7 5.8 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAG04972.1 - 2e-05 24.3 7.1 0.0011 18.6 6.4 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 AAG04972.1 - 0.00026 20.2 6.5 0.0018 17.4 3.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAG04972.1 - 0.0063 15.8 0.7 0.013 14.8 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAG04972.1 - 0.012 14.3 1.6 0.012 14.3 1.6 2.7 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 AAG04972.1 - 0.061 12.6 3.5 0.36 10.0 0.1 2.8 3 0 0 3 3 3 0 Thi4 family FAD_oxidored PF12831.7 AAG04972.1 - 0.41 9.9 6.9 0.41 9.9 4.4 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAG04972.1 - 0.44 9.8 1.9 0.41 9.8 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer2_3 PF13085.6 AAG04973.1 - 1.3e-30 105.6 0.0 2.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 AAG04973.1 - 3.7e-09 37.0 2.1 7.2e-09 36.1 2.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG04973.1 - 1.6e-08 34.8 15.4 2e-07 31.3 4.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG04973.1 - 3.4e-07 30.3 2.2 6.8e-07 29.3 2.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG04973.1 - 0.0011 19.1 3.1 0.0011 19.1 3.1 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAG04973.1 - 0.0014 19.2 8.3 0.011 16.3 8.6 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG04973.1 - 0.0063 17.4 2.3 3.6 8.6 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 AAG04973.1 - 0.017 15.3 3.5 1 9.6 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAG04973.1 - 0.09 12.9 5.4 2.1 8.5 1.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG04973.1 - 0.13 12.8 7.7 4.1 8.2 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 AAG04973.1 - 0.24 11.3 14.5 0.21 11.5 0.7 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAG04973.1 - 2.1 8.5 12.0 0.23 11.6 0.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Transket_pyr PF02779.24 AAG04974.1 - 5.9e-66 221.5 0.0 1e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 AAG04974.1 - 1.2e-55 188.6 0.1 1.9e-55 187.9 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 AAG04974.1 - 3.6e-55 185.8 0.0 6.6e-55 185.0 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 AAG04974.1 - 1.2e-17 63.2 0.1 2.4e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PFOR_II PF17147.4 AAG04974.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II 2-oxoacid_dh PF00198.23 AAG04975.1 - 2.1e-79 266.2 0.0 2.6e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAG04975.1 - 1.6e-20 72.7 5.3 3.5e-19 68.4 0.7 2.9 2 1 1 3 3 3 2 Biotin-requiring enzyme E3_binding PF02817.17 AAG04975.1 - 2.4e-16 59.8 0.7 7.8e-16 58.1 0.7 2.0 1 0 0 1 1 1 1 e3 binding domain GCV_H PF01597.19 AAG04975.1 - 0.034 14.0 2.1 1.6 8.6 0.2 2.6 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF4813 PF16072.5 AAG04975.1 - 0.039 13.6 23.7 0.044 13.5 22.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Pyr_redox_2 PF07992.14 AAG04976.1 - 3.8e-70 236.4 8.0 3.8e-70 236.4 8.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAG04976.1 - 1.2e-39 135.0 0.7 3.9e-39 133.3 0.7 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAG04976.1 - 3.5e-20 72.3 7.7 3.3e-18 66.0 0.7 3.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG04976.1 - 2.1e-13 50.2 3.5 5.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG04976.1 - 3.4e-10 39.6 6.7 3.5e-09 36.2 2.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AAG04976.1 - 2.4e-08 33.5 9.1 2.7e-07 30.1 0.7 3.3 3 0 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.19 AAG04976.1 - 3.5e-06 26.5 7.1 0.0092 15.3 0.7 2.7 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 AAG04976.1 - 4.3e-06 25.7 11.6 3.3e-05 22.8 0.4 3.7 3 1 1 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.7 AAG04976.1 - 5e-06 26.1 5.0 9.4e-06 25.2 2.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG04976.1 - 1.6e-05 24.3 3.2 1.7e-05 24.2 0.6 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 AAG04976.1 - 2.4e-05 24.5 3.1 0.096 12.9 0.6 3.0 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 AAG04976.1 - 4.5e-05 23.4 0.4 4.5e-05 23.4 0.4 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAG04976.1 - 0.00062 19.1 12.5 0.0025 17.1 0.6 3.2 3 2 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AAG04976.1 - 0.011 15.1 4.1 0.069 12.5 0.1 3.2 3 1 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 AAG04976.1 - 0.017 14.7 18.1 0.98 8.9 0.4 4.3 3 1 1 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAG04976.1 - 0.047 12.7 3.0 0.5 9.4 0.4 2.7 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 AAG04976.1 - 0.21 10.8 1.8 0.31 10.3 0.1 2.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG04976.1 - 0.38 10.3 5.9 0.31 10.6 0.3 2.8 3 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-grasp_2 PF08442.10 AAG04977.1 - 2.8e-83 278.4 0.0 4.2e-83 277.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 AAG04977.1 - 1.5e-24 86.5 3.4 1.5e-24 86.5 3.4 1.5 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 AAG04977.1 - 2.2e-13 50.2 0.3 4.8e-13 49.1 0.0 1.7 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 AAG04977.1 - 8.5e-06 25.7 0.1 2.4e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 AAG04977.1 - 0.0034 17.0 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 AAG04978.1 - 8.4e-32 109.7 0.5 8.4e-32 109.7 0.5 2.1 3 1 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 AAG04978.1 - 4.2e-22 78.6 0.4 6.5e-22 78.0 0.4 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AAG04978.1 - 1.5e-11 44.2 0.1 2.7e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAG04978.1 - 0.0023 18.4 0.0 0.0072 16.8 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain Branch_AA_trans PF05525.13 AAG04979.1 - 5.6e-161 536.2 32.3 6.4e-161 536.0 32.4 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein DUF599 PF04654.12 AAG04980.1 - 7.8e-62 208.4 10.6 9e-62 208.2 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 FAP PF07174.11 AAG04981.1 - 0.63 9.4 19.4 0.63 9.4 19.4 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CCDC53 PF10152.9 AAG04981.1 - 2 8.8 8.0 2.2 8.7 8.0 1.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex 4HBT PF03061.22 AAG04982.1 - 2e-10 40.9 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT PF03061.22 AAG04983.1 - 4.3e-13 49.4 0.0 6.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAG04983.1 - 3.2e-09 37.4 0.0 3.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily BPL_C PF02237.17 AAG04984.1 - 0.00056 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain HSP90 PF00183.18 AAG04985.1 - 1.2e-135 453.4 0.0 1.4e-132 443.3 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 AAG04985.1 - 4.3e-13 49.7 0.1 7.6e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAG04985.1 - 1.1e-11 44.7 0.1 1.9e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DLH PF01738.18 AAG04986.1 - 2.3e-41 141.7 0.0 2.7e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAG04986.1 - 8.3e-05 22.1 0.1 0.0045 16.5 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAG04986.1 - 0.049 12.9 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_transf_4 PF13439.6 AAG04986.1 - 0.051 13.6 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Pantoate_transf PF02548.15 AAG04987.1 - 1.6e-99 332.5 0.0 1.8e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase DHDPS PF00701.22 AAG04987.1 - 0.19 10.4 0.0 0.47 9.1 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family HTH_18 PF12833.7 AAG04988.1 - 1.2e-21 76.8 1.3 2.1e-21 76.0 1.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG04988.1 - 3.5e-13 49.3 0.0 2.7e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG04988.1 - 2.9e-07 30.4 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG04988.1 - 0.00018 21.2 0.1 0.00036 20.2 0.0 1.5 2 0 0 2 2 2 1 Cupin domain HTH_23 PF13384.6 AAG04988.1 - 0.03 14.1 0.3 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_30 PF13556.6 AAG04988.1 - 0.07 12.9 0.6 2.4 8.0 0.0 2.9 2 1 1 3 3 3 0 PucR C-terminal helix-turn-helix domain Cytochrome_CBB3 PF13442.6 AAG04989.1 - 4.7e-22 78.1 2.7 5.4e-09 36.3 0.0 3.7 3 1 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG04989.1 - 2e-17 64.1 0.0 1.5e-05 26.0 0.0 3.6 3 0 0 3 3 3 3 Cytochrome c Cytochrom_C550 PF14495.6 AAG04989.1 - 4.7e-05 23.1 0.0 1.9 8.2 0.0 3.7 4 0 0 4 4 4 3 Cytochrome c-550 domain Paired_CXXCH_1 PF09699.10 AAG04989.1 - 0.0014 18.3 5.9 4.1 7.2 0.3 3.4 3 0 0 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AAG04989.1 - 0.0049 16.8 0.1 9.8 6.3 0.0 3.2 3 0 0 3 3 3 1 Cytochrome c7 and related cytochrome c CCP_MauG PF03150.14 AAG04989.1 - 0.077 13.6 0.1 6.9 7.3 0.0 2.9 3 0 0 3 3 3 0 Di-haem cytochrome c peroxidase Ald_Xan_dh_C2 PF02738.18 AAG04990.1 - 6.8e-69 232.8 0.0 5.7e-28 97.7 0.0 3.2 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAG04990.1 - 0.00079 19.8 0.2 0.26 11.7 0.0 3.0 2 1 1 3 3 3 2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain TAT_signal PF10518.9 AAG04990.1 - 0.039 13.8 0.1 0.12 12.2 0.1 2.0 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence SUKH-3 PF14433.6 AAG04990.1 - 0.099 13.1 0.0 13 6.2 0.0 2.5 2 0 0 2 2 2 0 SUKH-3 immunity protein Fer2_2 PF01799.20 AAG04991.1 - 5e-28 96.9 0.2 5e-28 96.9 0.2 1.7 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAG04991.1 - 3e-06 27.1 0.1 3e-06 27.1 0.1 2.3 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAG04991.1 - 0.00089 19.2 3.7 0.0021 18.1 2.8 2.0 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAG04991.1 - 0.012 15.6 1.7 0.062 13.4 1.7 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AAG04991.1 - 9.3 6.2 12.5 0.15 11.9 4.4 2.2 3 0 0 3 3 3 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B MarR PF01047.22 AAG04992.1 - 1.2e-13 50.8 0.1 4.3e-13 49.0 0.0 1.9 3 0 0 3 3 3 1 MarR family MarR_2 PF12802.7 AAG04992.1 - 2.9e-12 46.3 0.6 4.9e-12 45.6 0.1 1.6 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAG04992.1 - 9.3e-09 35.7 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AAG04992.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SBP_bac_3 PF00497.20 AAG04993.1 - 1.6e-07 31.0 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Amidohydro_2 PF04909.14 AAG04994.1 - 3.6e-12 46.7 7.4 7.2e-12 45.7 7.4 1.5 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 AAG04994.1 - 0.0024 17.3 0.0 0.0044 16.4 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase DUF3859 PF12975.7 AAG04995.1 - 3.6e-45 153.2 0.1 4.1e-45 153.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3859) MG2 PF01835.19 AAG04995.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 MG2 domain HxlR PF01638.17 AAG04996.1 - 2.1e-19 69.1 0.0 3e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_45 PF14947.6 AAG04996.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DUF5397 PF17375.2 AAG04996.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5397) MCPsignal PF00015.21 AAG04997.1 - 1.1e-44 152.3 23.2 1.1e-44 152.3 23.2 3.0 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAG04997.1 - 1.6e-23 83.2 1.3 1.6e-23 83.2 1.3 3.5 4 1 0 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAG04997.1 - 2.2e-10 40.7 16.4 2.6e-08 34.1 0.4 5.1 5 1 0 5 5 5 2 HAMP domain TarH PF02203.15 AAG04997.1 - 1.9e-06 27.9 6.9 1.9e-06 27.9 6.9 3.8 3 1 0 4 4 4 1 Tar ligand binding domain homologue ANTH PF07651.16 AAG04997.1 - 0.00099 18.2 0.9 0.0057 15.7 0.3 2.2 2 0 0 2 2 2 1 ANTH domain PDGLE PF13190.6 AAG04997.1 - 0.033 14.1 2.4 0.044 13.7 0.1 2.4 2 0 0 2 2 2 0 PDGLE domain Ribonuclease_3 PF00636.26 AAG04997.1 - 0.045 14.4 0.2 0.36 11.5 0.1 2.5 3 0 0 3 3 3 0 Ribonuclease III domain IFT57 PF10498.9 AAG04997.1 - 1.4 7.8 16.5 0.026 13.5 4.0 2.8 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Dehydrin PF00257.19 AAG04997.1 - 6.4 7.3 6.2 1.6 9.3 2.2 1.9 2 0 0 2 2 2 0 Dehydrin ketoacyl-synt PF00109.26 AAG04998.1 - 5.4e-47 160.5 1.4 7.6e-47 160.0 1.4 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAG04998.1 - 3.9e-31 107.5 1.0 2.2e-29 101.9 0.3 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AAG04998.1 - 0.002 17.5 3.6 0.0035 16.7 1.2 2.3 2 1 1 3 3 3 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AAG04998.1 - 0.0099 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension FabA PF07977.13 AAG04999.1 - 1.2e-52 177.2 0.0 1.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain HATPase_c PF02518.26 AAG05000.1 - 1.9e-29 102.4 0.0 3.8e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAG05000.1 - 5.6e-28 97.4 0.1 1.8e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AAG05000.1 - 1.8e-19 69.5 4.8 2.6e-19 69.0 0.4 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF2222 PF09984.9 AAG05000.1 - 9.3e-10 38.6 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) HAMP PF00672.25 AAG05000.1 - 1.1e-09 38.6 0.1 2.7e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 HAMP domain GRIP PF01465.20 AAG05000.1 - 0.00014 21.7 1.0 0.035 14.0 0.1 3.0 3 0 0 3 3 3 1 GRIP domain YscO PF07321.12 AAG05000.1 - 0.0019 18.2 0.2 0.0058 16.6 0.2 1.8 1 0 0 1 1 1 1 Type III secretion protein YscO HATPase_c_3 PF13589.6 AAG05000.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GlutR_N PF05201.15 AAG05000.1 - 0.077 12.8 0.3 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, N-terminal domain HATPase_c_5 PF14501.6 AAG05000.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 GHKL domain Cyclophil_like2 PF18050.1 AAG05000.1 - 0.14 12.1 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Cyclophilin-like family ABC_sub_bind PF04392.12 AAG05001.1 - 0.0028 17.0 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter substrate binding protein TonB_dep_Rec PF00593.24 AAG05002.1 - 2.1e-26 93.9 12.8 2.1e-26 93.9 12.8 1.7 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG05002.1 - 5.5e-21 75.2 0.1 6e-20 71.8 0.1 2.3 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain NAD_Gly3P_dh_N PF01210.23 AAG05003.1 - 1.2e-51 174.7 0.0 1.9e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 AAG05003.1 - 4.9e-47 159.8 1.3 6.8e-47 159.3 0.6 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 AAG05003.1 - 1.8e-10 41.3 0.0 1e-09 38.8 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AAG05003.1 - 4.4e-07 29.7 0.0 7.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AAG05003.1 - 0.0003 21.0 0.0 0.0027 17.9 0.0 2.3 1 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AAG05003.1 - 0.0016 18.4 0.0 0.0041 17.0 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 AAG05003.1 - 0.0043 17.0 0.1 0.013 15.4 0.0 1.7 1 1 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AAG05003.1 - 0.006 16.8 0.0 0.36 11.1 0.0 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 AAG05003.1 - 0.013 15.7 0.0 0.096 13.0 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Semialdhyde_dh PF01118.24 AAG05003.1 - 0.082 13.3 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ring_hydroxyl_A PF00848.19 AAG05003.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) DUF4389 PF14333.6 AAG05004.1 - 1.5e-29 101.7 0.9 1.8e-29 101.5 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4389) KleE PF17394.2 AAG05004.1 - 0.65 10.2 3.1 0.52 10.6 2.0 1.4 1 1 0 1 1 1 0 Uncharacterized KleE stable inheritance protein His_Phos_1 PF00300.22 AAG05005.1 - 3.8e-16 59.4 0.8 3.5e-14 53.0 0.7 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AMP-binding PF00501.28 AAG05006.1 - 7.1e-91 304.9 0.0 8.4e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG05006.1 - 0.023 15.6 0.1 0.05 14.6 0.1 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain 4HBT PF03061.22 AAG05007.1 - 5.1e-14 52.4 0.3 6.7e-14 52.0 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAG05007.1 - 0.1 12.8 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily AraC_binding PF02311.19 AAG05008.1 - 2.1e-27 95.7 2.4 4e-27 94.8 2.4 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_18 PF12833.7 AAG05008.1 - 6.5e-23 80.8 0.6 1.4e-22 79.7 0.6 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05008.1 - 8.6e-12 44.8 0.0 1.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG05008.1 - 7.9e-05 22.3 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain HTH_Tnp_ISL3 PF13542.6 AAG05008.1 - 0.0017 17.7 1.3 0.25 10.8 0.0 3.2 2 1 1 3 3 3 2 Helix-turn-helix domain of transposase family ISL3 AraC_binding_2 PF14525.6 AAG05008.1 - 0.0022 17.7 5.0 0.0022 17.7 5.0 1.5 2 0 0 2 2 2 1 AraC-binding-like domain Sigma70_r3 PF04539.16 AAG05008.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 LysE PF01810.18 AAG05009.1 - 4e-35 121.0 10.1 5e-35 120.7 10.1 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAG05009.1 - 2 8.1 8.5 0.13 11.9 1.0 2.2 2 1 0 2 2 2 0 Integral membrane protein TerC family Abhydrolase_6 PF12697.7 AAG05010.1 - 1.1e-12 49.0 10.9 1.3e-12 48.8 10.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG05010.1 - 2.7e-05 23.6 0.0 0.00033 20.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAG05010.1 - 7.7e-05 22.9 0.0 0.00015 22.0 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 AAG05010.1 - 0.0079 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 AAG05010.1 - 0.011 15.4 0.0 0.08 12.6 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 AAG05010.1 - 0.036 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 AAG05010.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 AAG05011.1 - 2.2e-16 60.3 0.0 1.1e-15 57.9 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG05011.1 - 7.3e-13 49.6 9.8 8.7e-13 49.4 9.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG05011.1 - 9e-11 41.5 0.4 1.5e-10 40.8 0.4 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAG05011.1 - 0.00019 21.6 0.2 0.00024 21.3 0.2 1.4 1 1 0 1 1 1 1 Thioesterase domain GST_N PF02798.20 AAG05012.1 - 5.2e-17 62.0 0.0 7.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG05012.1 - 2.3e-13 50.2 0.0 3.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAG05012.1 - 4.5e-13 49.4 0.0 7.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG05012.1 - 1.4e-08 34.8 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG05012.1 - 0.0004 20.5 0.0 0.0008 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAG05012.1 - 0.003 17.6 0.2 0.0054 16.7 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4892 PF16234.5 AAG05013.1 - 6.4e-98 325.6 0.1 8.1e-98 325.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4892) AI-2E_transport PF01594.16 AAG05014.1 - 6.7e-40 137.2 22.6 7.8e-40 137.0 22.6 1.0 1 0 0 1 1 1 1 AI-2E family transporter MFS_1 PF07690.16 AAG05015.1 - 5.2e-20 71.7 42.8 5.2e-20 71.7 42.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FCD PF07729.12 AAG05016.1 - 1.5e-28 99.7 10.8 2.6e-28 98.9 10.8 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAG05016.1 - 2.1e-18 65.7 0.7 5e-18 64.5 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 AAG05016.1 - 0.0017 18.4 0.9 0.012 15.7 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.7 AAG05016.1 - 0.0026 17.9 0.0 0.0098 16.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 AAG05016.1 - 0.0034 17.3 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_Crp_2 PF13545.6 AAG05016.1 - 0.0059 16.5 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAG05016.1 - 0.0086 15.6 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAG05016.1 - 0.0094 15.7 0.9 0.074 12.9 0.1 2.6 3 0 0 3 3 3 1 IclR helix-turn-helix domain Sigma70_r3 PF04539.16 AAG05016.1 - 0.012 15.7 0.0 0.045 13.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 TrmB PF01978.19 AAG05016.1 - 0.016 15.1 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 AAG05016.1 - 0.023 14.4 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_8 PF02954.19 AAG05016.1 - 0.028 14.2 0.0 0.084 12.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family MarR_2 PF12802.7 AAG05016.1 - 0.22 11.4 4.2 1.3 9.0 0.0 3.5 4 1 1 5 5 5 0 MarR family 3HCDH PF00725.22 AAG05017.1 - 2e-57 191.8 0.0 1e-31 109.4 0.0 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 AAG05017.1 - 2.9e-57 193.4 0.0 4.8e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAG05017.1 - 7.9e-05 22.9 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_RFF PF18321.1 AAG05017.1 - 0.0011 19.3 0.4 0.014 15.9 0.2 3.0 3 0 0 3 3 3 1 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain NAD_Gly3P_dh_N PF01210.23 AAG05017.1 - 0.0031 17.5 0.2 0.0074 16.3 0.1 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 AAG05017.1 - 0.0041 17.6 0.2 0.015 15.8 0.1 2.1 2 0 0 2 2 2 1 XdhC Rossmann domain F420_oxidored PF03807.17 AAG05017.1 - 0.0065 17.0 0.3 0.017 15.7 0.3 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AAG05017.1 - 0.008 15.8 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 AAG05017.1 - 0.016 14.6 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AAG05017.1 - 0.044 14.0 0.2 0.18 12.1 0.2 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DFP PF04127.15 AAG05017.1 - 0.046 13.5 0.1 0.073 12.9 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein AlaDh_PNT_C PF01262.21 AAG05017.1 - 0.088 12.1 0.4 0.16 11.2 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_9 PF01075.17 AAG05017.1 - 0.19 11.0 0.1 0.31 10.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Acetyltransf_6 PF13480.7 AAG05017.1 - 1 9.5 5.7 0.78 9.9 0.1 3.3 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain ECH_1 PF00378.20 AAG05018.1 - 1.4e-72 244.0 0.0 1.6e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG05018.1 - 7.3e-36 124.3 0.2 4.8e-33 115.1 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase KicB PF03882.14 AAG05018.1 - 0.085 13.1 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 MukF winged-helix domain Hydrolase PF00702.26 AAG05018.1 - 0.1 12.9 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HTH_IclR PF09339.10 AAG05019.1 - 1.3e-16 60.1 0.7 3.2e-16 58.9 0.7 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain IclR PF01614.18 AAG05019.1 - 7.9e-11 41.9 0.0 1.5e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial transcriptional regulator MarR PF01047.22 AAG05019.1 - 0.0015 18.4 0.0 0.0086 16.0 0.0 2.3 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AAG05019.1 - 0.0032 17.3 0.0 0.011 15.5 0.0 2.0 1 1 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAG05019.1 - 0.0038 16.8 0.0 0.0074 15.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 AAG05019.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG05019.1 - 0.073 13.1 0.2 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAG05019.1 - 0.089 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_3 PF01381.22 AAG05019.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix Acyl-CoA_dh_1 PF00441.24 AAG05020.1 - 1.1e-49 168.5 4.3 2.1e-49 167.6 4.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05020.1 - 2.2e-30 104.7 0.0 4.5e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG05020.1 - 2.5e-30 105.4 0.0 5.6e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAG05020.1 - 4.8e-25 88.4 2.4 8.7e-25 87.5 2.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Potass_KdpF PF09604.10 AAG05021.1 - 1.4e-08 34.5 2.8 1.6e-08 34.3 2.8 1.1 1 0 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) KdpA PF03814.15 AAG05022.1 - 7.1e-245 813.4 19.8 8.5e-245 813.1 19.8 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit Ecm33 PF12454.8 AAG05022.1 - 0.12 12.5 0.2 0.29 11.3 0.2 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein DUF4131 PF13567.6 AAG05022.1 - 2.7 7.6 24.8 0.067 12.9 0.8 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Hydrolase PF00702.26 AAG05023.1 - 2.8e-32 112.7 0.2 5.9e-32 111.7 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 AAG05023.1 - 5.4e-32 110.8 1.6 5.4e-32 110.8 1.6 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.7 AAG05023.1 - 3.6e-07 30.8 0.7 3.7e-06 27.5 0.1 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAG05023.1 - 0.00031 20.6 1.3 0.0024 17.6 0.9 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF872 PF05915.12 AAG05023.1 - 0.68 10.1 2.5 2 8.6 2.5 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) KdpC PF02669.15 AAG05024.1 - 2e-61 207.0 0.0 2.3e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain KdpD PF02702.17 AAG05025.1 - 6.2e-91 303.5 0.1 9.6e-91 302.9 0.1 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 AAG05025.1 - 1.3e-26 92.5 10.5 2.5e-26 91.6 10.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 AAG05025.1 - 7.6e-23 81.2 0.0 1.9e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG05025.1 - 5.4e-14 52.0 1.1 5.4e-14 52.0 1.1 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Usp PF00582.26 AAG05025.1 - 3.1e-12 47.2 6.1 4.7e-11 43.4 2.0 3.9 3 1 0 3 3 3 1 Universal stress protein family HATPase_c_2 PF13581.6 AAG05025.1 - 0.0007 19.6 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAG05025.1 - 0.036 13.9 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 AAG05025.1 - 0.043 14.2 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 GAF domain GAF_2 PF13185.6 AAG05025.1 - 4.5 7.6 10.2 0.67 10.2 0.1 3.9 4 1 0 4 4 4 0 GAF domain Response_reg PF00072.24 AAG05026.1 - 8.2e-25 87.2 0.0 1.5e-24 86.3 0.0 1.4 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG05026.1 - 2.3e-22 78.8 0.0 4.7e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Glutaminase PF04960.15 AAG05027.1 - 4.3e-111 370.7 0.0 4.9e-111 370.5 0.0 1.0 1 0 0 1 1 1 1 Glutaminase DUF4893 PF16233.5 AAG05028.1 - 7.9e-22 77.6 0.0 9.5e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4893) Patatin PF01734.22 AAG05029.1 - 5.3e-18 65.9 4.8 4e-16 59.8 4.8 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase AIRS_C PF02769.22 AAG05031.1 - 4.9e-33 114.5 0.1 7.1e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AAG05031.1 - 9.3e-20 71.1 0.7 1.9e-19 70.1 0.7 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AAA_18 PF13238.6 AAG05032.1 - 0.0039 17.7 0.0 0.0099 16.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AAG05032.1 - 0.0085 15.4 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 AAG05032.1 - 0.0099 16.3 0.3 0.051 14.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Rhodanese PF00581.20 AAG05032.1 - 0.013 16.0 0.1 0.081 13.4 0.0 2.3 2 1 0 2 2 2 0 Rhodanese-like domain AAA_22 PF13401.6 AAG05032.1 - 0.098 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavin_Reduct PF01613.18 AAG05033.1 - 3.6e-18 66.1 0.9 4.6e-18 65.7 0.9 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF5086 PF16985.5 AAG05034.1 - 3.1e-61 205.1 0.1 3.5e-61 204.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5086) MCPsignal PF00015.21 AAG05035.1 - 5.3e-47 159.8 38.5 7.9e-45 152.7 26.9 3.6 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAG05035.1 - 1.4e-12 47.8 23.8 3.5e-12 46.5 2.3 5.6 5 0 0 5 5 5 2 HAMP domain HBM PF16591.5 AAG05035.1 - 5.3e-05 22.8 2.5 5.3e-05 22.8 2.5 4.6 2 2 0 4 4 4 1 Helical bimodular sensor domain DUF3450 PF11932.8 AAG05035.1 - 0.001 18.5 14.6 0.001 18.5 14.6 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF3450) Elf4 PF07011.11 AAG05035.1 - 0.11 12.4 2.1 2 8.4 2.0 2.8 1 1 1 2 2 2 0 Early Flowering 4 domain PG_binding_1 PF01471.18 AAG05035.1 - 0.14 12.3 3.4 0.44 10.8 0.4 3.1 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Sigma70_ner PF04546.13 AAG05035.1 - 0.16 11.9 6.9 5.2 6.9 1.6 3.0 2 0 0 2 2 2 0 Sigma-70, non-essential region PhaP_Bmeg PF09602.10 AAG05035.1 - 0.21 11.5 4.1 2.9 7.8 0.1 2.9 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Imm1 PF14430.6 AAG05035.1 - 0.38 11.4 2.9 8.8 7.0 0.0 3.5 3 1 0 3 3 3 0 Immunity protein Imm1 DUF2408 PF10303.9 AAG05035.1 - 0.42 11.2 6.7 1.3 9.6 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2408) BLOC1_2 PF10046.9 AAG05035.1 - 0.49 10.7 12.8 2.2 8.6 0.1 4.5 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KELK PF15796.5 AAG05035.1 - 1 9.8 4.7 3.3 8.2 1.1 3.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SLS PF14611.6 AAG05035.1 - 1.6 8.5 6.5 1.5 8.6 0.0 2.9 2 1 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator TPPK_C PF12555.8 AAG05035.1 - 1.8 8.6 11.9 0.61 10.2 2.8 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal AAA_13 PF13166.6 AAG05035.1 - 2.4 6.7 15.2 2.7 6.5 8.7 2.3 1 1 1 2 2 2 0 AAA domain DUF948 PF06103.11 AAG05035.1 - 3.9 7.8 30.8 0.14 12.4 2.9 5.4 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) FH2 PF02181.23 AAG05035.1 - 5.8 5.9 7.0 2.7 7.0 0.1 2.5 2 1 0 2 2 2 0 Formin Homology 2 Domain DUF1664 PF07889.12 AAG05035.1 - 6.8 6.8 16.7 17 5.5 0.1 4.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) GCN5L1 PF06320.13 AAG05035.1 - 7.1 6.8 15.9 0.76 9.9 6.4 3.8 3 2 1 4 4 4 0 GCN5-like protein 1 (GCN5L1) Sulfate_transp PF00916.20 AAG05036.1 - 2.8e-93 312.7 17.5 3.9e-93 312.2 17.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 AAG05036.1 - 3.1e-18 65.5 0.0 5.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AAG05036.1 - 0.00037 20.8 0.5 0.00037 20.8 0.5 2.6 2 0 0 2 2 2 1 STAS domain ADH_N_2 PF16884.5 AAG05037.1 - 1e-38 131.5 0.0 2.1e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 AAG05037.1 - 4.3e-20 72.0 0.4 8.5e-20 71.1 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAG05037.1 - 1.1e-12 49.2 0.0 2.6e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.16 AAG05037.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein adh_short_C2 PF13561.6 AAG05038.1 - 6.9e-72 241.8 8.7 8.1e-72 241.5 8.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG05038.1 - 2.4e-58 196.8 4.8 2.9e-58 196.6 4.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG05038.1 - 4.3e-11 43.0 3.8 5.8e-11 42.6 3.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG05038.1 - 0.0013 18.3 2.3 0.008 15.7 2.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAG05038.1 - 0.088 11.8 0.3 0.36 9.8 0.3 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SBF PF01758.16 AAG05039.1 - 2.4e-33 115.5 16.4 3.7e-33 114.8 16.4 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 AAG05039.1 - 4.7e-17 62.3 23.4 6.5e-17 61.8 23.4 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) AbrB PF05145.12 AAG05039.1 - 0.32 9.9 31.6 0.27 10.1 11.3 3.4 1 1 1 3 3 3 0 Transition state regulatory protein AbrB DUF21 PF01595.20 AAG05039.1 - 6 6.5 11.4 1.2 8.8 6.8 2.1 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain BenE PF03594.13 AAG05040.1 - 4.5e-168 558.9 36.9 5.2e-168 558.7 36.9 1.0 1 0 0 1 1 1 1 Benzoate membrane transport protein DUF4282 PF14110.6 AAG05041.1 - 0.031 15.0 0.5 0.031 15.0 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) NADH5_C PF06455.11 AAG05041.1 - 0.39 10.3 7.0 2.6 7.6 0.9 2.2 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus MarR_2 PF12802.7 AAG05042.1 - 3.7e-11 42.7 0.1 8.7e-11 41.5 0.1 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAG05042.1 - 3.7e-05 23.6 0.0 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAG05042.1 - 0.00042 19.8 0.0 0.00085 18.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 AAG05042.1 - 0.00058 20.3 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AAG05042.1 - 0.039 14.0 0.5 0.11 12.5 0.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain Aminotran_1_2 PF00155.21 AAG05043.1 - 2.7e-30 105.8 0.0 3.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AAG05043.1 - 1.3e-11 44.0 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase HEAT_2 PF13646.6 AAG05043.1 - 0.043 14.2 0.1 1.1 9.7 0.0 2.8 2 1 0 2 2 2 0 HEAT repeats GST_N PF02798.20 AAG05044.1 - 9.2e-17 61.2 0.0 2.8e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAG05044.1 - 6.7e-16 58.5 0.0 1.7e-14 54.0 0.0 2.5 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG05044.1 - 1.2e-11 44.6 0.0 1.7e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AAG05044.1 - 1.5e-11 44.4 0.0 3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAG05044.1 - 5.3e-11 42.4 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG05044.1 - 2.9e-08 33.8 0.0 4.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AAG05044.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAG05044.1 - 0.019 15.7 0.0 0.056 14.2 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain T6SS_VasJ PF16989.5 AAG05045.1 - 3.6e-78 262.6 15.3 7.9e-78 261.4 15.3 1.6 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 AAG05045.1 - 8.1e-30 103.4 0.7 8.1e-30 103.4 0.7 2.4 3 0 0 3 3 3 1 ImpA, N-terminal, type VI secretion system RACo_linker PF17650.1 AAG05045.1 - 0.032 14.1 0.8 1.1 9.2 0.1 2.8 2 0 0 2 2 2 0 RACo linker region T6SS_VipA PF05591.12 AAG05046.1 - 8.4e-53 178.3 0.0 9.4e-53 178.2 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 VipB PF05943.12 AAG05047.1 - 1.7e-182 606.9 0.0 2e-182 606.7 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath GPW_gp25 PF04965.14 AAG05048.1 - 1.1e-15 57.2 0.0 1.3e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme T6SS_TssF PF05947.12 AAG05049.1 - 1.7e-111 373.7 0.0 1.9e-111 373.5 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF T6SS_TssG PF06996.11 AAG05050.1 - 9.4e-89 297.6 2.9 1.2e-88 297.3 2.9 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG HalOD2 PF18547.1 AAG05050.1 - 0.14 12.1 0.1 0.38 10.7 0.3 1.7 2 0 0 2 2 2 0 Halobacterial output domain 2 AAA_2 PF07724.14 AAG05051.1 - 1.4e-43 149.0 0.0 5.3e-42 143.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAG05051.1 - 4.2e-29 100.5 1.7 8.3e-29 99.6 0.1 2.2 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 AAG05051.1 - 1.1e-19 71.2 0.0 1e-09 38.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAG05051.1 - 2.2e-13 50.4 0.1 2.9e-09 37.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 AAG05051.1 - 4.7e-11 42.6 4.7 6.3e-10 39.0 0.5 3.1 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 AAG05051.1 - 7.4e-09 36.0 0.7 0.047 14.0 0.1 5.1 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.6 AAG05051.1 - 1.7e-07 31.8 31.7 0.00021 21.7 0.0 7.3 6 2 1 7 7 6 2 AAA ATPase domain Clp_N PF02861.20 AAG05051.1 - 1.3e-05 25.2 4.2 0.00031 20.8 1.0 3.3 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component TniB PF05621.11 AAG05051.1 - 1.5e-05 24.5 0.0 0.24 10.8 0.0 3.4 2 1 1 3 3 3 2 Bacterial TniB protein Sigma54_activat PF00158.26 AAG05051.1 - 1.8e-05 24.5 0.2 0.0029 17.3 0.0 2.8 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 AAG05051.1 - 6.1e-05 22.6 0.0 0.41 10.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 AAG05051.1 - 6.1e-05 23.0 0.1 0.027 14.4 0.0 3.3 2 1 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 AAG05051.1 - 0.00066 19.5 0.0 0.83 9.4 0.0 3.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 AAG05051.1 - 0.00069 19.4 1.3 0.092 12.5 0.1 3.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAG05051.1 - 0.00083 19.3 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 AAG05051.1 - 0.0019 18.7 2.8 1.7 9.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 AAG05051.1 - 0.0045 16.7 0.1 0.97 9.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.15 AAG05051.1 - 0.0061 16.6 0.0 2.6 8.0 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AAG05051.1 - 0.0068 16.4 0.0 6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 AAG05051.1 - 0.013 14.7 0.3 8.9 5.4 0.0 3.0 2 1 1 3 3 3 0 TIP49 P-loop domain RNA_helicase PF00910.22 AAG05051.1 - 0.015 15.7 0.0 9.9 6.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase SRP54 PF00448.22 AAG05051.1 - 0.015 14.9 0.1 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 AAG05051.1 - 0.021 15.2 0.9 12 6.2 0.0 3.5 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 AAG05051.1 - 0.022 14.8 0.4 4.1 7.5 0.1 3.3 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Hpr_kinase_C PF07475.12 AAG05051.1 - 0.025 14.1 0.3 0.096 12.2 0.0 2.0 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_25 PF13481.6 AAG05051.1 - 0.028 14.0 8.6 0.85 9.2 0.1 4.1 3 2 1 4 4 4 0 AAA domain AAA_24 PF13479.6 AAG05051.1 - 0.035 13.8 0.0 2 8.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAG05051.1 - 0.043 14.4 5.6 0.88 10.1 0.0 3.5 4 0 0 4 4 2 0 AAA domain Roc PF08477.13 AAG05051.1 - 0.056 13.7 0.0 6.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 AAG05051.1 - 0.07 12.5 0.4 2 7.7 0.1 2.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 AAG05051.1 - 0.1 13.1 1.2 21 5.6 0.0 3.6 4 0 0 4 4 3 0 ABC transporter TsaE PF02367.17 AAG05051.1 - 0.12 12.4 0.0 8.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAG05051.1 - 0.19 11.9 4.4 8 6.6 0.0 3.9 3 1 1 4 4 4 0 AAA domain ATPase_2 PF01637.18 AAG05051.1 - 0.2 11.5 0.1 6.9 6.5 0.0 3.0 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea Spc7 PF08317.11 AAG05051.1 - 8.5 5.2 8.2 17 4.2 8.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Sigma54_activat PF00158.26 AAG05052.1 - 1e-69 233.6 0.0 1.7e-69 232.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG05052.1 - 6.1e-22 78.2 0.0 1.9e-21 76.6 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG05052.1 - 6.7e-14 51.4 1.4 6.7e-14 51.4 1.4 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAG05052.1 - 2.8e-07 30.6 0.0 5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) GAF_2 PF13185.6 AAG05052.1 - 2.1e-05 24.9 0.1 0.00013 22.3 0.0 2.3 2 1 1 3 3 3 1 GAF domain HTH_30 PF13556.6 AAG05052.1 - 0.00041 20.1 0.1 0.0012 18.6 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA_16 PF13191.6 AAG05052.1 - 0.0079 16.6 0.2 0.026 14.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain HTH_50 PF18024.1 AAG05052.1 - 0.01 15.4 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_2 PF07724.14 AAG05052.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_1 PF00126.27 AAG05052.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Mg_chelatase PF01078.21 AAG05052.1 - 0.032 13.6 0.0 6.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAG05052.1 - 0.041 14.3 0.0 0.075 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AAG05052.1 - 0.061 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 AAG05052.1 - 0.31 10.2 0.0 0.45 9.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain FHA PF00498.26 AAG05054.1 - 4e-13 49.5 0.0 8.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain T6SS-SciN PF12790.7 AAG05055.1 - 3.6e-40 136.4 0.0 4.3e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 AAG05056.1 - 7.2e-142 473.0 0.6 8.1e-142 472.9 0.6 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 AAG05057.1 - 1.6e-66 223.9 0.2 2.1e-66 223.6 0.2 1.1 1 0 0 1 1 1 1 Type VI secretion system protein DotU ImcF-related_N PF14331.6 AAG05058.1 - 4.3e-78 262.2 2.6 8.5e-78 261.3 2.6 1.5 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF-related PF06761.12 AAG05058.1 - 7.8e-70 235.8 4.9 7.8e-70 235.8 4.9 2.9 4 0 0 4 4 4 1 Intracellular multiplication and human macrophage-killing IcmF_C PF06744.12 AAG05058.1 - 7.1e-57 192.3 0.0 1.3e-56 191.4 0.0 1.5 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal AAA_29 PF13555.6 AAG05058.1 - 0.034 13.9 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRC-1 PF08832.10 AAG05058.1 - 0.071 14.2 0.0 0.14 13.2 0.0 1.4 1 0 0 1 1 1 0 Steroid receptor coactivator DUF4131 PF13567.6 AAG05058.1 - 0.082 12.6 3.5 0.17 11.5 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AAA_21 PF13304.6 AAG05058.1 - 0.14 11.9 0.4 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSF PF00482.23 AAG05058.1 - 0.69 9.9 3.1 2.2 8.3 0.3 3.5 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F AAA_16 PF13191.6 AAG05058.1 - 4.6 7.6 11.5 0.27 11.6 0.2 3.5 3 1 0 3 3 3 0 AAA ATPase domain PP2C_2 PF13672.6 AAG05059.1 - 3e-15 56.4 0.4 4.2e-15 56.0 0.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AAG05059.1 - 2e-11 44.0 0.0 8.3e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 AAG05059.1 - 1.5e-09 38.0 0.3 1e-08 35.3 0.3 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.25 AAG05060.1 - 3.1e-38 131.7 0.0 3.9e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAG05060.1 - 2.8e-25 89.1 0.0 3.2e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AAG05060.1 - 0.00018 21.5 6.5 0.004 17.1 0.0 3.1 1 1 2 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 AAG05060.1 - 0.0039 16.8 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH_6_hur PF04655.14 AAG05060.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Kdo PF06293.14 AAG05060.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyoxalase PF00903.25 AAG05061.1 - 1.4e-08 35.0 0.0 1.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG05061.1 - 0.00011 22.4 0.0 0.014 15.7 0.0 2.1 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG05061.1 - 0.021 15.6 0.0 0.034 14.9 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain Hemerythrin PF01814.23 AAG05062.1 - 1.4e-13 51.6 3.6 1.7e-13 51.3 3.6 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF3843 PF12954.7 AAG05062.1 - 0.014 14.4 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) DUF3050 PF11251.8 AAG05062.1 - 0.018 14.7 0.1 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) GTP_cyclohydroI PF01227.22 AAG05063.1 - 1.7e-76 255.7 0.6 1.9e-76 255.5 0.6 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I Smr PF01713.21 AAG05064.1 - 1.2e-21 76.9 0.1 1.8e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 Smr domain NdhM PF10664.9 AAG05064.1 - 0.084 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Neurensin PF14927.6 AAG05065.1 - 0.0078 15.9 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 1 Neurensin Acyl_transf_3 PF01757.22 AAG05065.1 - 0.012 14.7 1.5 0.016 14.3 1.5 1.2 1 0 0 1 1 1 0 Acyltransferase family RskA PF10099.9 AAG05065.1 - 0.029 14.7 0.3 0.03 14.6 0.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2207 PF09972.9 AAG05065.1 - 0.067 11.9 0.1 0.075 11.8 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Zip PF02535.22 AAG05065.1 - 0.11 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4381 PF14316.6 AAG05065.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) DUF998 PF06197.13 AAG05065.1 - 0.62 9.6 12.3 3.4 7.2 5.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF3040 PF11239.8 AAG05065.1 - 9.5 6.6 10.6 1.2e+02 3.0 9.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Isochorismatase PF00857.20 AAG05066.1 - 4e-35 121.5 0.0 4.8e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF2325 PF10087.9 AAG05066.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) MTS PF05175.14 AAG05067.1 - 7.3e-19 67.9 0.0 1e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 AAG05067.1 - 9.2e-10 38.5 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG05067.1 - 1.2e-09 38.8 0.0 1.3e-07 32.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAG05067.1 - 1.4e-05 24.9 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 AAG05067.1 - 1.8e-05 24.6 0.0 6.2e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAG05067.1 - 2e-05 24.2 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 AAG05067.1 - 2.7e-05 24.1 0.0 5.8e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 AAG05067.1 - 5.6e-05 23.7 2.0 6.1e-05 23.5 0.1 2.1 2 0 0 2 2 1 1 PrmC N-terminal domain Methyltransf_16 PF10294.9 AAG05067.1 - 6.6e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 AAG05067.1 - 0.00092 19.8 0.2 0.0056 17.3 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 AAG05067.1 - 0.0016 18.2 0.0 0.0051 16.5 0.0 1.9 2 1 1 3 3 3 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 AAG05067.1 - 0.0041 16.7 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 AAG05067.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 AAG05067.1 - 0.011 15.1 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 AAG05067.1 - 0.02 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein TrmK PF04816.12 AAG05067.1 - 0.037 13.6 0.0 0.075 12.6 0.0 1.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_12 PF08242.12 AAG05067.1 - 0.055 14.2 0.0 0.25 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DivIC PF04977.15 AAG05068.1 - 0.18 11.6 1.6 0.31 10.8 1.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Hydrolase_4 PF12146.8 AAG05069.1 - 1.4e-14 53.9 0.0 4.1e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAG05069.1 - 2.6e-10 41.3 3.1 4.1e-10 40.7 3.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG05069.1 - 2.2e-07 30.8 0.0 0.0033 17.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 AAG05069.1 - 0.005 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Glyco_transf_4 PF13439.6 AAG05069.1 - 0.039 14.0 0.1 0.08 12.9 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Peptidase_S9 PF00326.21 AAG05069.1 - 0.15 11.5 0.0 6 6.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 AAG05069.1 - 0.18 11.6 0.0 0.56 10.0 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chorismate_synt PF01264.21 AAG05070.1 - 2.4e-139 463.6 0.0 2.7e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Nfu_N PF08712.11 AAG05070.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal MFS_1_like PF12832.7 AAG05071.1 - 2e-84 283.7 21.6 2.7e-84 283.3 21.6 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 AAG05071.1 - 3.6e-21 75.5 49.1 6.1e-13 48.4 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 AAG05071.1 - 4.9e-18 65.3 15.7 6.7e-18 64.9 15.7 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 AAG05071.1 - 0.0001 21.2 5.9 0.0001 21.2 5.9 2.5 2 1 0 2 2 2 2 LacY proton/sugar symporter Aldolase_II PF00596.21 AAG05072.1 - 1.3e-37 129.5 0.0 1.5e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PQQ_2 PF13360.6 AAG05072.1 - 0.049 13.2 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain ARD PF03079.14 AAG05073.1 - 8e-36 123.6 0.0 9.1e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 AAG05073.1 - 0.00023 20.8 1.0 0.00049 19.8 1.0 1.5 1 0 0 1 1 1 1 Cupin domain Hydrolase PF00702.26 AAG05074.1 - 4.7e-05 23.8 0.1 8.7e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAG05074.1 - 0.0082 16.2 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AlkA_N PF06029.11 AAG05075.1 - 6e-32 110.3 0.1 1.1e-31 109.5 0.1 1.5 1 0 0 1 1 1 1 AlkA N-terminal domain HhH-GPD PF00730.25 AAG05075.1 - 3.3e-08 33.9 0.0 5.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAG05075.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 AAG05075.1 - 0.046 14.3 0.0 0.32 11.6 0.0 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix domain Spermine_synth PF01564.17 AAG05076.1 - 2.5e-63 212.9 0.0 3.6e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 AAG05076.1 - 3.9e-15 55.5 0.2 7.3e-15 54.6 0.2 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 AAG05076.1 - 1.3e-05 25.8 0.0 5.7e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG05076.1 - 6.5e-05 23.5 0.0 0.00021 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG05076.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 AAG05076.1 - 0.043 14.6 0.0 0.12 13.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PP-binding_2 PF14573.6 AAG05076.1 - 0.075 13.3 0.3 1.6 9.0 0.2 2.5 2 0 0 2 2 2 0 Acyl-carrier Methyltransf_30 PF05430.11 AAG05076.1 - 0.078 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Str_synth PF03088.16 AAG05077.1 - 8.3e-06 25.8 0.0 0.00012 22.1 0.0 2.6 2 1 1 3 3 3 1 Strictosidine synthase SGL PF08450.12 AAG05077.1 - 0.0012 18.4 0.0 0.12 11.9 0.0 2.5 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 AAG05077.1 - 0.065 13.5 0.0 5.9 7.5 0.0 2.9 2 0 0 2 2 2 0 Two component regulator propeller Sulfatase PF00884.23 AAG05078.1 - 1.7e-45 155.8 0.1 2.3e-45 155.4 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AAG05078.1 - 0.0002 21.1 0.0 0.00076 19.2 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase FA_desaturase PF00487.24 AAG05078.1 - 0.19 11.6 6.2 0.086 12.7 3.5 1.8 1 1 1 2 2 2 0 Fatty acid desaturase DUF229 PF02995.17 AAG05078.1 - 0.24 10.0 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF3413 PF11893.8 AAG05078.1 - 6.3 5.9 11.7 0.084 12.0 3.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Bac_export_2 PF01312.19 AAG05079.1 - 2e-110 369.1 0.2 2.2e-110 368.9 0.2 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Bac_export_1 PF01311.20 AAG05080.1 - 1.7e-51 175.0 27.2 2e-51 174.8 27.2 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_3 PF01313.19 AAG05081.1 - 5.3e-26 90.4 7.4 6.4e-26 90.1 7.4 1.2 1 0 0 1 1 1 1 Bacterial export proteins, family 3 DUF502 PF04367.13 AAG05081.1 - 0.049 13.5 1.0 0.099 12.5 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF502) TM_helix PF05552.12 AAG05081.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.1 2 0 0 2 2 2 0 Conserved TM helix FliP PF00813.20 AAG05082.1 - 1.9e-68 230.1 5.6 2.3e-68 229.9 5.6 1.0 1 0 0 1 1 1 1 FliP family UNC-93 PF05978.16 AAG05082.1 - 0.14 11.9 0.1 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 OppC_N PF12911.7 AAG05082.1 - 0.37 10.8 0.0 0.37 10.8 0.0 3.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C FliMN_C PF01052.20 AAG05083.1 - 1.5e-21 76.2 0.0 7.2e-17 61.2 0.1 2.3 2 0 0 2 2 2 2 Type III flagellar switch regulator (C-ring) FliN C-term Flg_hook PF02120.16 AAG05084.1 - 1.8e-09 37.4 5.3 3.3e-09 36.5 5.3 1.4 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK YscO PF07321.12 AAG05085.1 - 5.5e-46 156.2 36.2 6.2e-46 156.1 36.2 1.0 1 0 0 1 1 1 1 Type III secretion protein YscO ATP-synt_ab PF00006.25 AAG05086.1 - 2.5e-78 262.6 0.0 3.3e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AAG05086.1 - 3.2e-25 87.8 0.5 5.4e-25 87.1 0.5 1.4 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 AAG05086.1 - 1.1e-10 41.8 0.1 2.3e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF87 PF01935.17 AAG05086.1 - 0.024 14.7 0.5 0.058 13.5 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 AAG05086.1 - 0.059 13.9 0.2 0.15 12.5 0.1 1.7 2 0 0 2 2 2 0 ABC transporter HrpJ PF07201.11 AAG05087.1 - 2.9e-38 131.8 10.9 3.1e-38 131.7 8.8 1.8 2 0 0 2 2 2 1 HrpJ-like domain HWE_HK PF07536.14 AAG05087.1 - 0.059 14.1 3.0 0.062 14.0 0.3 2.3 2 1 0 2 2 2 0 HWE histidine kinase Drf_FH3 PF06367.16 AAG05087.1 - 0.096 12.3 0.1 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Diaphanous FH3 Domain DinB_2 PF12867.7 AAG05087.1 - 1.8 9.1 5.1 1.8 9.1 0.2 2.8 1 1 1 2 2 2 0 DinB superfamily TyeA PF09059.10 AAG05088.1 - 2.6e-32 110.7 0.5 2.9e-32 110.6 0.5 1.0 1 0 0 1 1 1 1 TyeA CesT PF05932.13 AAG05089.1 - 7.6e-05 22.8 0.8 9.6e-05 22.5 0.8 1.1 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family Type_III_YscX PF09474.10 AAG05090.1 - 4.5e-54 181.9 0.6 5e-54 181.7 0.6 1.0 1 0 0 1 1 1 1 Type III secretion system YscX (type_III_YscX) TPR_14 PF13428.6 AAG05091.1 - 3.9e-08 33.5 14.9 0.00019 22.0 0.8 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AAG05091.1 - 2.6e-06 27.8 6.3 0.0013 19.2 0.9 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAG05091.1 - 5.2e-05 23.8 1.1 5.2e-05 23.8 1.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAG05091.1 - 0.00076 19.4 4.0 0.19 12.0 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAG05091.1 - 0.0025 17.9 0.2 0.12 12.6 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 AAG05091.1 - 0.0071 15.6 1.8 0.0085 15.3 1.8 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAG05091.1 - 0.024 15.2 2.2 0.024 15.2 2.2 3.8 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAG05091.1 - 0.054 13.9 0.4 0.99 9.9 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAG05091.1 - 0.057 13.7 8.0 0.91 9.9 2.2 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAG05091.1 - 0.063 13.9 3.7 0.22 12.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAG05091.1 - 0.26 11.2 8.2 14 5.7 0.1 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAG05091.1 - 0.33 11.1 5.2 0.4 10.8 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat FHIPEP PF00771.20 AAG05092.1 - 1.2e-238 794.0 5.7 1.3e-238 793.8 5.7 1.0 1 0 0 1 1 1 1 FHIPEP family DUF3626 PF12294.8 AAG05092.1 - 0.039 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) LcrR PF09621.10 AAG05093.1 - 7.2e-71 236.0 0.1 8e-71 235.9 0.1 1.0 1 0 0 1 1 1 1 Type III secretion system regulator (LcrR) LcrG PF07216.12 AAG05094.1 - 8.6e-42 141.0 2.4 9.7e-42 140.8 2.4 1.0 1 0 0 1 1 1 1 LcrG protein PAP_PilO PF06864.12 AAG05094.1 - 0.13 11.1 0.1 0.14 11.0 0.1 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) LcrV PF04792.12 AAG05095.1 - 2.7e-68 230.6 0.0 3.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 V antigen (LcrV) protein NanE PF04131.14 AAG05095.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.4 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TilS PF09179.11 AAG05095.1 - 0.021 15.3 1.2 0.021 15.3 1.2 1.9 2 0 0 2 2 2 0 TilS substrate binding domain TPR_12 PF13424.6 AAG05096.1 - 0.00016 21.9 14.3 0.014 15.6 2.6 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAG05096.1 - 0.0002 21.2 12.7 0.0098 15.9 0.9 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAG05096.1 - 0.00032 21.3 14.5 0.0055 17.3 3.9 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 AAG05096.1 - 0.00064 19.6 3.1 0.00064 19.6 3.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AAG05096.1 - 0.0023 18.1 5.2 0.071 13.3 2.5 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 AAG05096.1 - 0.005 17.3 10.1 0.29 11.7 0.6 3.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAG05096.1 - 0.0095 15.7 11.7 0.035 13.9 0.7 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAG05096.1 - 0.022 15.4 15.7 0.26 12.0 0.3 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 AAG05096.1 - 0.059 13.1 2.0 2.2 8.0 0.0 3.1 2 1 1 3 3 3 0 TPR repeat TPR_7 PF13176.6 AAG05096.1 - 0.1 12.6 5.0 5.2 7.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 AAG05096.1 - 0.27 11.4 0.2 0.27 11.4 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAG05096.1 - 0.56 10.2 6.1 3.9 7.5 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAG05096.1 - 4.8 8.3 12.7 2.1 9.4 0.2 3.8 3 2 1 4 4 3 0 Tetratricopeptide repeat SseC PF04888.12 AAG05097.1 - 1.2e-58 199.2 35.4 1.2e-58 199.2 35.4 1.5 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family DUF4225 PF13988.6 AAG05097.1 - 0.00039 20.0 2.9 0.00075 19.1 2.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4225) DUF4064 PF13273.6 AAG05097.1 - 0.011 16.1 2.8 0.011 16.1 2.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) DUF4199 PF13858.6 AAG05097.1 - 0.034 14.5 0.8 0.034 14.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2207 PF09972.9 AAG05097.1 - 0.054 12.2 0.2 0.079 11.7 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TolA_bind_tri PF16331.5 AAG05097.1 - 0.072 13.2 9.1 0.25 11.4 0.6 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation Ribosomal_L21p PF00829.21 AAG05097.1 - 0.082 13.2 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein zf-ZPR1 PF03367.13 AAG05097.1 - 0.088 12.7 2.3 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 ZPR1 zinc-finger domain CENP-H PF05837.12 AAG05097.1 - 0.12 12.7 8.7 5 7.6 3.8 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Myotub-related PF06602.14 AAG05097.1 - 0.13 11.2 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain V_ATPase_I PF01496.19 AAG05097.1 - 0.15 10.0 0.7 2.7 5.8 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.24 AAG05097.1 - 0.2 11.6 3.7 0.86 9.5 0.5 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD KxDL PF10241.9 AAG05097.1 - 0.52 10.6 0.1 0.52 10.6 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF5362 PF17319.2 AAG05097.1 - 1.6 8.6 9.9 0.18 11.7 4.4 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5362) Val_tRNA-synt_C PF10458.9 AAG05097.1 - 1.8 8.9 10.1 2 8.7 0.1 3.2 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm MCU PF04678.13 AAG05097.1 - 2.3 8.3 5.4 1.6 8.8 1.5 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter GrpE PF01025.19 AAG05097.1 - 4.3 7.0 10.2 6.3 6.4 0.3 2.3 2 0 0 2 2 2 0 GrpE YopD PF05844.12 AAG05098.1 - 2.9e-154 512.4 17.8 3.3e-154 512.2 17.8 1.0 1 0 0 1 1 1 1 YopD protein CesT PF05932.13 AAG05099.1 - 1.8e-24 86.1 2.7 2.1e-24 85.9 2.7 1.0 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family T3SS_ExsE PF18286.1 AAG05100.1 - 1.1e-29 102.1 1.8 1.4e-29 101.8 1.8 1.2 1 0 0 1 1 1 1 Type III secretion system ExsE UTP15_C PF09384.10 AAG05100.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 UTP15 C terminal Peptidase_S8_N PF16361.5 AAG05100.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 N-terminal of Subtilase family YscW PF09619.10 AAG05101.1 - 5.8e-12 45.9 0.0 6.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) HTH_18 PF12833.7 AAG05102.1 - 2.1e-23 82.4 0.2 4.7e-23 81.2 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05102.1 - 2.2e-21 75.4 0.2 1.4e-10 41.0 0.2 2.8 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family EutQ PF06249.12 AAG05102.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ ExsD PF16806.5 AAG05103.1 - 3.6e-101 338.1 4.7 4.1e-101 337.9 4.7 1.0 1 0 0 1 1 1 1 Antiactivator protein ExsD CesT PF05932.13 AAG05104.1 - 1.3e-28 99.5 1.0 1.5e-28 99.3 1.0 1.0 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family YbjN PF10722.9 AAG05104.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.2 1 1 0 1 1 1 1 Putative bacterial sensory transduction regulator Secretin PF00263.21 AAG05105.1 - 6.9e-41 139.7 0.1 1.2e-40 138.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAG05105.1 - 6.2e-21 74.6 1.0 1.1e-14 54.5 0.1 2.8 3 0 0 3 3 3 2 Bacterial type II/III secretion system short domain DUF4974 PF16344.5 AAG05105.1 - 0.0092 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) Yop-YscD_ppl PF16693.5 AAG05106.1 - 6.3e-95 317.4 0.5 7.7e-95 317.1 0.5 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, periplasmic domain Yop-YscD_cpl PF16697.5 AAG05106.1 - 3e-20 72.3 0.0 6.6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain T2SSB PF16537.5 AAG05106.1 - 0.002 17.7 0.1 0.018 14.6 0.0 2.4 2 0 0 2 2 2 1 Type II secretion system protein B T3SS_needle_E PF08988.10 AAG05107.1 - 1.2e-22 79.9 3.0 1.3e-22 79.7 3.0 1.0 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle DUF2894 PF11445.8 AAG05107.1 - 0.069 13.6 0.4 0.069 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Surfac_D-trimer PF09006.11 AAG05107.1 - 0.98 9.4 3.3 17 5.4 0.4 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation T3SS_needle_F PF09392.10 AAG05108.1 - 2.7e-26 91.6 2.0 3.1e-26 91.4 2.0 1.0 1 0 0 1 1 1 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Type_III_YscG PF09477.10 AAG05109.1 - 7.9e-57 190.3 0.5 8.8e-57 190.2 0.5 1.0 1 0 0 1 1 1 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_2 PF07719.17 AAG05109.1 - 0.48 10.7 3.0 2.7 8.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat T3SS_needle_reg PF09025.10 AAG05110.1 - 4.6e-22 78.6 0.0 5.2e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 YopR, type III needle-polymerisation regulator T3SS_basalb_I PF17001.5 AAG05111.1 - 1.6e-27 95.9 1.0 2e-27 95.6 1.0 1.1 1 0 0 1 1 1 1 Type III secretion basal body protein I, YscI, HrpB, PscI SHNi-TPR PF10516.9 AAG05111.1 - 0.02 14.4 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 SHNi-TPR YscJ_FliF PF01514.17 AAG05112.1 - 1.5e-26 93.3 0.0 2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family YscK PF06578.12 AAG05113.1 - 2.2e-92 308.3 4.0 2.4e-92 308.2 4.0 1.0 1 0 0 1 1 1 1 YOP proteins translocation protein K (YscK) SpdB PF05122.13 AAG05113.1 - 0.19 11.9 0.6 0.34 11.1 0.6 1.3 1 0 0 1 1 1 0 Mobile element transfer protein FliH PF02108.16 AAG05114.1 - 1.3e-17 64.1 1.2 2.1e-17 63.4 1.2 1.3 1 0 0 1 1 1 1 Flagellar assembly protein FliH NolV PF06635.12 AAG05114.1 - 3.4e-10 39.7 7.0 4.2e-10 39.4 7.0 1.1 1 0 0 1 1 1 1 Nodulation protein NolV HrpE PF06188.12 AAG05114.1 - 0.00044 20.2 7.1 0.00052 19.9 7.1 1.1 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E DUF1623 PF07785.11 AAG05114.1 - 0.0099 16.0 0.2 0.017 15.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1623) Glyco_hydro_3 PF00933.21 AAG05115.1 - 7.6e-83 278.5 0.0 1.1e-82 278.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 AAG05115.1 - 5.7e-61 206.0 0.0 8.6e-61 205.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 AAG05115.1 - 3.8e-22 78.2 0.0 7.8e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PHP PF02811.19 AAG05115.1 - 0.003 17.9 0.0 0.0049 17.2 0.0 1.3 1 0 0 1 1 1 1 PHP domain EAL PF00563.20 AAG05116.1 - 4.2e-72 242.5 0.1 9e-72 241.4 0.1 1.6 1 0 0 1 1 1 1 EAL domain MHYT PF03707.16 AAG05116.1 - 1.5e-54 182.0 38.3 3e-21 75.3 1.9 4.7 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat GGDEF PF00990.21 AAG05116.1 - 1.9e-51 174.0 0.5 2.8e-51 173.4 0.5 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAG05116.1 - 0.00084 19.6 3.9 0.0024 18.1 2.3 2.7 2 1 0 2 2 2 1 GGDEF-like domain Peptidase_U4 PF03419.13 AAG05116.1 - 1.1 8.5 16.9 0.014 14.7 8.5 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA RraB PF06877.11 AAG05117.1 - 6.6e-21 75.0 0.0 7.4e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Regulator of ribonuclease activity B GATase PF00117.28 AAG05118.1 - 1.1e-16 61.2 0.0 1.4e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAG05118.1 - 0.00013 21.8 0.1 0.00026 20.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase C26 Abhydrolase_6 PF12697.7 AAG05118.1 - 0.17 12.5 9.7 0.27 11.8 9.7 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family GATase_3 PF07685.14 AAG05118.1 - 0.26 10.8 0.0 0.34 10.5 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CP_ATPgrasp_2 PF14403.6 AAG05119.1 - 1.8e-165 550.4 0.0 2.1e-165 550.2 0.0 1.0 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AAG05119.1 - 7.2e-154 511.7 0.2 1e-153 511.3 0.1 1.3 2 0 0 2 2 2 1 A circularly permuted ATPgrasp SPOR PF05036.13 AAG05119.1 - 0.052 13.9 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation related domain ATPgrasp_YheCD PF14398.6 AAG05119.1 - 0.12 11.6 0.0 2.5 7.3 0.0 2.6 2 1 1 3 3 3 0 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 AAG05119.1 - 0.16 11.2 0.0 1.6 7.9 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Alpha-E PF04168.12 AAG05120.1 - 3.6e-93 312.6 6.4 4e-93 312.4 6.4 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. Transglut_core PF01841.19 AAG05121.1 - 1.3e-21 77.1 0.5 1.3e-21 77.1 0.5 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Bact_transglu_N PF08379.10 AAG05121.1 - 5.3e-20 72.1 0.8 8.7e-20 71.4 0.8 1.4 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core3 PF13471.6 AAG05121.1 - 0.00091 19.1 0.6 0.0018 18.2 0.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Proteasome PF00227.26 AAG05122.1 - 4.1e-09 36.2 0.0 5.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit rpo132 PF12415.8 AAG05122.1 - 0.15 11.3 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase Cytochrom_C PF00034.21 AAG05123.1 - 3.7e-10 40.8 0.0 6.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG05123.1 - 5.1e-10 39.5 0.0 1.4e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Mem_trans PF03547.18 AAG05124.1 - 3.1e-24 85.1 17.7 2.6e-14 52.4 9.1 2.0 1 1 1 2 2 2 2 Membrane transport protein Thiolase_N PF00108.23 AAG05125.1 - 3.1e-49 167.7 0.3 1.7e-46 158.7 0.0 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG05125.1 - 8.3e-48 161.1 1.1 2.8e-47 159.4 0.8 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG05125.1 - 0.00017 21.3 1.1 0.00043 20.0 0.1 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 AAG05125.1 - 0.0017 18.5 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAG05125.1 - 0.024 14.5 0.4 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Dodecin PF07311.12 AAG05125.1 - 0.12 12.6 0.1 0.55 10.5 0.1 2.1 1 1 1 2 2 2 0 Dodecin 3HCDH_N PF02737.18 AAG05126.1 - 1.9e-60 203.8 1.1 2.1e-59 200.4 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 AAG05126.1 - 6.7e-32 110.8 0.1 1.4e-31 109.7 0.1 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 AAG05126.1 - 1.8e-22 79.7 0.6 3.3e-19 69.3 0.0 3.5 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 AAG05126.1 - 2.3e-17 63.5 0.1 4e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 AAG05126.1 - 0.0038 17.4 0.3 0.02 15.1 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAG05126.1 - 0.014 14.8 0.1 0.037 13.4 0.1 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAG05126.1 - 0.058 12.7 2.2 0.15 11.3 0.9 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 AAG05126.1 - 0.17 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 AAG05126.1 - 0.76 10.4 5.2 0.21 12.2 1.5 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent LysR_substrate PF03466.20 AAG05127.1 - 2.5e-32 111.9 2.0 4.1e-32 111.3 2.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05127.1 - 6e-21 74.2 2.2 1.2e-20 73.1 2.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG05127.1 - 0.006 16.4 0.8 0.017 14.9 0.8 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HxlR PF01638.17 AAG05127.1 - 0.021 14.6 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 HxlR-like helix-turn-helix HTH_20 PF12840.7 AAG05127.1 - 0.028 14.5 0.7 0.064 13.3 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG05127.1 - 0.08 12.9 0.2 0.21 11.6 0.2 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Aldo_ket_red PF00248.21 AAG05128.1 - 7.2e-71 238.8 0.0 8.5e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SGL PF08450.12 AAG05129.1 - 4.5e-05 23.1 0.0 0.054 13.1 0.0 2.8 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AAG05129.1 - 0.0057 16.6 6.0 46 4.3 0.0 4.9 5 0 0 5 5 5 3 NHL repeat GST_N_3 PF13417.6 AAG05130.1 - 2e-12 47.3 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 AAG05130.1 - 1.4e-10 41.2 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 AAG05130.1 - 2.9e-09 37.1 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PAS_3 PF08447.12 AAG05130.1 - 0.064 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold GATase PF00117.28 AAG05131.1 - 3.2e-10 40.1 0.0 4.4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAG05131.1 - 0.094 12.5 0.2 0.26 11.0 0.2 1.8 1 1 0 1 1 1 0 Peptidase C26 Macro PF01661.21 AAG05135.1 - 2.8e-06 27.3 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Macro domain DUF3459 PF11941.8 AAG05135.1 - 0.024 15.0 0.1 0.039 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) GBP PF02263.19 AAG05135.1 - 0.17 11.1 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Sugarporin_N PF11471.8 AAG05136.1 - 0.03 14.3 1.9 0.039 13.9 1.9 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ECH_1 PF00378.20 AAG05137.1 - 2.1e-32 112.4 0.5 2.3e-32 112.3 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG05137.1 - 1.3e-09 38.0 0.2 1.6e-09 37.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Acetyltransf_CG PF14542.6 AAG05138.1 - 1.8e-22 79.3 0.1 2.7e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 AAG05138.1 - 6.7e-05 22.8 0.0 9.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG05138.1 - 0.00061 20.0 0.0 0.00079 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 AAG05138.1 - 0.082 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase DAHP_synth_1 PF00793.20 AAG05139.1 - 1.5e-93 312.7 0.0 1.8e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family HyaE PF07449.11 AAG05140.1 - 0.0031 17.4 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 AAG05140.1 - 0.0082 16.1 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAG05140.1 - 0.038 14.4 0.0 3.8 8.0 0.0 2.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1223 PF06764.11 AAG05140.1 - 0.079 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) ApbA PF02558.16 AAG05141.1 - 2.7e-38 131.0 0.0 3.7e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 AAG05141.1 - 5.1e-25 88.1 0.0 8.4e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal UDPG_MGDP_dh_N PF03721.14 AAG05141.1 - 0.0086 15.7 0.2 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AAG05141.1 - 0.086 12.7 0.1 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAG05141.1 - 0.16 12.6 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Usp PF00582.26 AAG05142.1 - 3.8e-26 92.3 0.3 4.5e-26 92.0 0.3 1.1 1 0 0 1 1 1 1 Universal stress protein family LysR_substrate PF03466.20 AAG05143.1 - 7.7e-39 133.2 0.0 1e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05143.1 - 4e-16 58.7 0.0 7.6e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG05143.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain PAPS_reduct PF01507.19 AAG05145.1 - 1.4e-47 162.0 0.0 1.7e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HHH_9 PF17674.1 AAG05145.1 - 0.077 13.9 0.0 0.15 13.0 0.0 1.4 1 0 0 1 1 1 0 HHH domain Cytochrom_D1 PF02239.16 AAG05145.1 - 0.22 10.0 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain HAD PF12710.7 AAG05146.1 - 6.3e-10 39.8 0.0 9.2e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG05146.1 - 1.8e-07 31.7 0.0 2.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 AAG05146.1 - 0.0074 15.7 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase_3 PF08282.12 AAG05146.1 - 0.0095 15.7 0.0 0.023 14.5 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CEP209_CC5 PF16574.5 AAG05146.1 - 0.21 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 Chorismate_bind PF00425.18 AAG05147.1 - 5.1e-99 331.0 0.0 6.3e-99 330.7 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AAG05147.1 - 2.5e-16 60.2 0.0 6.6e-15 55.6 0.0 2.6 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region HTH_32 PF13565.6 AAG05147.1 - 0.012 16.2 0.2 1.8 9.3 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain GerE PF00196.19 AAG05148.1 - 2.2e-17 62.3 0.1 4e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_MalT PF17874.1 AAG05148.1 - 1.1e-14 54.5 24.1 3e-13 49.9 22.6 2.6 2 0 0 2 2 2 1 MalT-like TPR region Sigma70_r4_2 PF08281.12 AAG05148.1 - 5.4e-07 29.2 0.6 3e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG05148.1 - 2.8e-06 26.8 0.1 1.2e-05 24.7 0.1 2.2 1 0 0 1 1 1 1 Sigma-70, region 4 AAA_16 PF13191.6 AAG05148.1 - 7.6e-06 26.4 0.1 7.6e-06 26.4 0.1 3.7 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 AAG05148.1 - 8.9e-05 22.8 0.6 0.00042 20.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain HTH_24 PF13412.6 AAG05148.1 - 0.022 14.3 0.1 0.2 11.2 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 AAG05148.1 - 0.024 15.1 0.4 0.76 10.3 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain NACHT PF05729.12 AAG05148.1 - 0.03 14.2 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TPR_12 PF13424.6 AAG05148.1 - 4.1 7.7 12.4 12 6.3 0.1 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat GerE PF00196.19 AAG05149.1 - 2.5e-18 65.4 0.1 5.7e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_MalT PF17874.1 AAG05149.1 - 2e-13 50.4 16.0 3.8e-13 49.5 16.0 1.4 1 0 0 1 1 1 1 MalT-like TPR region AAA_16 PF13191.6 AAG05149.1 - 4.4e-10 40.2 0.4 4.4e-10 40.2 0.4 3.8 4 1 0 4 4 4 1 AAA ATPase domain Sigma70_r4_2 PF08281.12 AAG05149.1 - 0.0001 21.9 0.5 0.00088 18.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 AAG05149.1 - 0.00019 20.9 0.1 0.00043 19.8 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AAG05149.1 - 0.00035 20.3 0.1 0.0013 18.5 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG05149.1 - 0.00054 19.7 0.1 0.0021 17.8 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain AAA_22 PF13401.6 AAG05149.1 - 0.0067 16.7 0.0 0.029 14.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAG05149.1 - 0.02 14.5 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain HTH_40 PF14493.6 AAG05149.1 - 0.023 15.2 0.1 0.087 13.3 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3150 PF11348.8 AAG05149.1 - 0.023 13.9 0.1 0.044 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) MeaB PF03308.16 AAG05149.1 - 0.068 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PAP_central PF04928.17 AAG05149.1 - 0.13 11.2 0.0 0.63 9.0 0.0 1.9 2 0 0 2 2 2 0 Poly(A) polymerase central domain TPR_4 PF07721.14 AAG05149.1 - 0.31 11.8 0.0 0.31 11.8 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAG05149.1 - 0.34 11.2 2.8 6.1 7.3 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAG05149.1 - 0.56 10.4 8.3 2.7 8.2 0.1 4.4 4 0 0 4 4 2 0 Tetratricopeptide repeat HTH_20 PF12840.7 AAG05149.1 - 3.4 7.8 6.7 2.4 8.3 0.1 3.3 3 0 0 3 3 2 0 Helix-turn-helix domain TPR_19 PF14559.6 AAG05149.1 - 4.4 7.9 16.4 1.9 9.1 0.2 6.2 6 1 0 7 7 7 0 Tetratricopeptide repeat Peptidase_C39 PF03412.15 AAG05151.1 - 1.2e-20 73.7 0.0 2.7e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase C39 family Peptidase_C39_2 PF13529.6 AAG05151.1 - 0.047 14.2 0.3 0.46 11.0 0.3 2.1 1 1 0 1 1 1 0 Peptidase_C39 like family DUF3335 PF11814.8 AAG05151.1 - 0.21 11.0 0.0 21 4.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase_C39 like family DUF4370 PF14290.6 AAG05152.1 - 0.11 12.4 0.5 0.19 11.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) Toluene_X PF03349.16 AAG05153.1 - 3.9e-151 503.5 0.3 4.4e-151 503.3 0.3 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) Porin_4 PF13609.6 AAG05153.1 - 7.9e-06 25.8 1.2 0.00021 21.2 0.1 2.4 2 1 0 2 2 2 1 Gram-negative porin OMP_b-brl PF13505.6 AAG05153.1 - 0.00011 22.4 8.9 0.041 14.0 0.9 3.6 2 1 1 3 3 3 2 Outer membrane protein beta-barrel domain DUF2490 PF10677.9 AAG05153.1 - 0.0061 16.5 4.9 3.5 7.5 1.9 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF2490) YjbH PF06082.11 AAG05153.1 - 0.017 14.0 0.5 2.1 7.1 0.1 2.2 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH YadA_anchor PF03895.15 AAG05153.1 - 0.037 14.1 0.7 3.3 7.9 0.1 4.0 4 1 0 4 4 4 0 YadA-like membrane anchor domain SARAF PF06682.12 AAG05153.1 - 0.3 10.7 0.9 0.42 10.2 0.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MalM PF07148.12 AAG05154.1 - 1.6e-28 99.1 0.0 2.7e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Maltose operon periplasmic protein precursor (MalM) DUF4124 PF13511.6 AAG05154.1 - 1.5e-10 41.3 4.1 1.4e-05 25.3 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4124) DUF2551 PF10826.8 AAG05154.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) ATPgrasp_ST PF14397.6 AAG05155.1 - 3e-103 345.0 0.0 3.5e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 AAG05155.1 - 1.9e-09 37.2 0.0 0.0003 20.1 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.11 AAG05155.1 - 3.4e-09 36.6 0.0 5.9e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AAG05155.1 - 8.5e-09 35.7 0.0 0.0035 17.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain GSH-S_ATP PF02955.16 AAG05155.1 - 5.4e-07 29.2 0.1 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic glutathione synthetase, ATP-grasp domain TTL PF03133.15 AAG05155.1 - 0.00076 18.7 0.0 0.061 12.4 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family 7TM_transglut PF14402.6 AAG05156.1 - 8.1e-95 317.0 17.8 1.3e-94 316.3 17.8 1.3 1 0 0 1 1 1 1 7 transmembrane helices usually fused to an inactive transglutaminase Transglut_i_TM PF14400.6 AAG05156.1 - 5.1e-47 159.9 0.0 7.4e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Inactive transglutaminase fused to 7 transmembrane helices DUF4418 PF14387.6 AAG05156.1 - 5.3 7.3 10.5 5.4 7.2 3.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4418) Zn_protease PF05618.11 AAG05157.1 - 2.7e-51 173.1 0.0 3.1e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease gag-asp_proteas PF13975.6 AAG05157.1 - 0.046 14.3 0.0 0.14 12.7 0.0 1.8 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Kinase-PPPase PF03618.14 AAG05158.1 - 4.3e-77 259.3 0.0 4.8e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase AAA_14 PF13173.6 AAG05158.1 - 0.052 13.6 0.1 5.6 7.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain PPDK_N PF01326.19 AAG05159.1 - 3.4e-120 401.2 0.1 4.8e-120 400.7 0.1 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 AAG05159.1 - 2.5e-63 213.9 0.0 1.3e-62 211.6 0.0 1.9 2 0 0 2 2 2 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 AAG05159.1 - 2.9e-26 91.0 0.5 6.5e-26 89.9 0.5 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Abhydrolase_6 PF12697.7 AAG05160.1 - 8.1e-14 52.8 13.4 1.1e-13 52.4 13.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG05160.1 - 1.7e-11 44.3 0.4 9.9e-10 38.5 0.9 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG05160.1 - 2.3e-11 43.5 0.0 1.5e-09 37.5 0.2 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 RraA-like PF03737.15 AAG05161.1 - 3.1e-46 157.2 0.8 3.5e-46 157.1 0.8 1.0 1 0 0 1 1 1 1 Aldolase/RraA CorA PF01544.18 AAG05162.1 - 1.8e-56 191.7 0.0 2e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2721 PF11026.8 AAG05162.1 - 0.077 12.9 0.4 4.1 7.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CK2S PF15011.6 AAG05162.1 - 0.18 11.6 2.0 0.57 10.0 0.3 2.1 1 1 1 2 2 2 0 Casein Kinase 2 substrate FUSC PF04632.12 AAG05162.1 - 0.76 8.2 4.5 0.1 11.1 0.8 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family Plasmid_RAQPRD PF09686.10 AAG05162.1 - 2.9 8.2 5.8 1.9 8.7 1.7 2.6 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TM_helix PF05552.12 AAG05164.1 - 5.4e-20 71.1 12.0 7.7e-13 48.2 4.8 4.3 5 0 0 5 5 5 2 Conserved TM helix MS_channel PF00924.18 AAG05164.1 - 7.9e-09 35.4 5.0 7.9e-09 35.4 5.0 2.7 3 0 0 3 3 3 1 Mechanosensitive ion channel FtsX PF02687.21 AAG05164.1 - 8.3 7.0 23.1 9.5 6.8 4.5 3.1 2 1 0 2 2 2 0 FtsX-like permease family Sigma70_r2 PF04542.14 AAG05165.1 - 1.5e-19 69.5 0.1 1.5e-19 69.5 0.1 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG05165.1 - 3.7e-12 45.5 0.1 6.8e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAG05165.1 - 7.3e-09 35.2 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG05165.1 - 0.0035 17.3 1.2 0.0068 16.3 1.2 1.4 1 1 0 1 1 1 1 ECF sigma factor OprF PF05736.11 AAG05166.1 - 1.6e-97 324.6 7.4 2.4e-97 324.0 7.4 1.2 1 0 0 1 1 1 1 OprF membrane domain OmpA PF00691.20 AAG05166.1 - 1.7e-24 86.0 0.4 3.4e-24 85.0 0.2 1.6 2 0 0 2 2 2 1 OmpA family OMP_b-brl PF13505.6 AAG05166.1 - 1.3e-11 44.9 11.6 1.3e-11 44.9 11.6 1.6 2 0 0 2 2 2 1 Outer membrane protein beta-barrel domain OmpW PF03922.14 AAG05166.1 - 0.0024 17.8 0.6 0.0049 16.8 0.6 1.6 1 0 0 1 1 1 1 OmpW family TSP_3 PF02412.18 AAG05166.1 - 0.31 10.8 12.6 0.1 12.3 9.5 1.8 2 0 0 2 2 2 0 Thrombospondin type 3 repeat TP_methylase PF00590.20 AAG05167.1 - 4.9e-47 160.6 0.2 5.6e-47 160.4 0.2 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Molybdopterin PF00384.22 AAG05168.1 - 8.3e-84 282.0 0.0 9.9e-84 281.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAG05168.1 - 2.4e-27 95.2 0.0 4.1e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAG05168.1 - 9.1e-18 64.0 1.4 9.1e-18 64.0 1.4 2.2 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_BFD PF04324.15 AAG05168.1 - 2.4e-09 37.4 0.8 6.1e-09 36.1 0.8 1.8 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 AAG05169.1 - 3.2e-15 55.9 0.0 3.7e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 AAG05169.1 - 3.3e-14 52.6 0.0 7.7e-14 51.4 0.0 1.5 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.14 AAG05170.1 - 3.6e-58 197.1 0.3 8.7e-58 195.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AAG05170.1 - 1.7e-31 108.4 7.3 3.9e-15 55.9 0.0 3.5 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 AAG05170.1 - 3.1e-27 95.0 0.1 5.3e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 AAG05170.1 - 5.2e-23 81.4 3.4 8.5e-21 74.3 0.1 4.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 AAG05170.1 - 1.7e-16 59.9 0.0 5.9e-16 58.2 0.1 1.9 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain NIR_SIR_ferr PF03460.17 AAG05170.1 - 6.8e-15 54.7 0.0 1.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.6 AAG05170.1 - 9.7e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAG05170.1 - 4.7e-06 26.4 1.8 0.2 11.2 0.0 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AAG05170.1 - 0.00015 21.8 1.5 3 7.8 0.0 4.1 3 1 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 AAG05170.1 - 0.00044 19.7 0.1 0.07 12.4 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 AAG05170.1 - 0.00064 20.1 0.0 0.0075 16.7 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 AAG05170.1 - 0.0016 17.2 0.0 2.8 6.5 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 AAG05170.1 - 0.0018 17.6 0.3 0.017 14.4 0.1 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 AAG05170.1 - 0.0043 16.0 0.8 0.05 12.5 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 AAG05170.1 - 0.0083 15.3 1.8 0.04 13.0 0.2 2.6 2 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAG05170.1 - 0.011 15.9 0.1 0.15 12.3 0.2 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 AAG05170.1 - 0.021 14.7 0.3 0.047 13.6 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 AAG05170.1 - 0.03 13.4 3.3 0.036 13.1 0.5 2.3 2 1 1 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 AAG05170.1 - 0.038 13.2 1.4 0.12 11.5 0.9 2.0 1 1 1 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 AAG05170.1 - 0.15 11.3 1.2 6.4 6.0 0.2 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pkinase PF00069.25 AAG05171.1 - 3.7e-26 92.1 0.0 4.9e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAG05171.1 - 8.3e-16 58.0 0.0 1.4e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PP2C_2 PF13672.6 AAG05171.1 - 3e-07 30.3 0.9 5.4e-07 29.5 0.9 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AAG05171.1 - 2.2e-05 24.2 0.0 0.055 13.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 AAG05171.1 - 0.00018 21.5 0.1 0.0003 20.8 0.1 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Kinase-like PF14531.6 AAG05171.1 - 0.12 11.7 0.0 0.5 9.6 0.0 1.9 3 0 0 3 3 3 0 Kinase-like MFS_1 PF07690.16 AAG05172.1 - 3.5e-38 131.4 50.3 3.5e-38 131.4 50.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAG05172.1 - 6.7e-06 24.9 30.7 8.2e-05 21.3 14.0 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 AAG05172.1 - 5.4 5.7 17.4 3.6 6.3 6.1 2.3 2 0 0 2 2 2 0 LacY proton/sugar symporter Alginate_lyase2 PF08787.11 AAG05173.1 - 4.7e-61 206.7 0.4 5.2e-61 206.5 0.4 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.6 AAG05173.1 - 0.0017 18.2 2.0 0.045 13.6 2.0 2.2 1 1 0 1 1 1 1 Polysaccharide lyase ANTAR PF03861.14 AAG05174.1 - 4.4e-16 58.4 7.9 8.4e-16 57.6 7.9 1.5 1 0 0 1 1 1 1 ANTAR domain Response_reg PF00072.24 AAG05174.1 - 3.1e-09 37.0 0.0 5.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain NMT1_2 PF13379.6 AAG05175.1 - 3.1e-90 302.3 0.1 3.7e-90 302.0 0.1 1.1 1 0 0 1 1 1 1 NMT1-like family GHMP_kinases_N PF00288.26 AAG05175.1 - 0.0015 18.8 0.5 0.34 11.2 0.2 2.7 2 0 0 2 2 2 2 GHMP kinases N terminal domain NMT1 PF09084.11 AAG05175.1 - 0.033 14.1 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 NMT1/THI5 like Aconitase_2_N PF06434.13 AAG05176.1 - 1.3e-96 322.1 0.0 2.1e-96 321.5 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 AAG05176.1 - 2.1e-67 226.0 0.2 3.6e-67 225.2 0.2 1.4 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 AAG05176.1 - 2.5e-42 145.4 0.0 1.8e-40 139.3 0.0 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) PI-TkoII_IV PF18714.1 AAG05176.1 - 0.034 13.6 0.0 5.1 6.6 0.0 2.3 1 1 0 2 2 2 0 DNA polymerase II intein Domain IV Ketoacyl-synt_C PF02801.22 AAG05176.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain DUF1289 PF06945.13 AAG05177.1 - 2e-15 56.3 0.2 3.8e-15 55.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Usp PF00582.26 AAG05178.1 - 8.5e-22 78.2 0.3 1.1e-13 51.8 0.2 3.0 2 1 1 3 3 3 3 Universal stress protein family UPF0180 PF03698.13 AAG05178.1 - 0.13 12.4 0.1 0.37 11.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) MiaE PF06175.11 AAG05179.1 - 3.2e-88 295.4 6.7 2.3e-69 233.7 1.3 2.0 1 1 1 2 2 2 2 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) MiaE_2 PF13794.6 AAG05179.1 - 0.00052 19.8 0.1 0.0034 17.1 0.0 1.9 1 1 0 2 2 2 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Rubrerythrin PF02915.17 AAG05179.1 - 0.014 15.8 0.1 0.037 14.4 0.1 1.6 1 1 1 2 2 2 0 Rubrerythrin Ald_deCOase PF11266.8 AAG05179.1 - 0.046 13.4 0.1 0.058 13.1 0.1 1.2 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase DUF1281 PF06924.11 AAG05179.1 - 0.075 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF3231 PF11553.8 AAG05179.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) Band_7 PF01145.25 AAG05180.1 - 1.3e-38 132.8 1.1 1.3e-38 132.8 1.1 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Metallophos PF00149.28 AAG05181.1 - 6.8e-09 36.5 0.0 1.1e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAG05181.1 - 1.1e-08 35.4 0.4 2.3e-07 31.2 0.4 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DnaJ-X PF14308.6 AAG05181.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 X-domain of DnaJ-containing Pro_isomerase PF00160.21 AAG05182.1 - 5.1e-46 156.8 0.9 5.7e-46 156.7 0.9 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_1c PF00749.21 AAG05183.1 - 3.6e-109 364.5 0.0 4.4e-109 364.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AAG05183.1 - 4.8e-58 195.9 0.0 7.5e-58 195.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 AAG05184.1 - 1.9e-133 444.5 0.0 2.3e-133 444.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 AAG05184.1 - 2.6e-23 82.2 1.0 8.7e-23 80.6 1.0 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 AAG05184.1 - 7e-14 51.4 0.1 9.8e-07 27.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 AAG05184.1 - 1e-07 31.3 0.0 3.5e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 AAG05184.1 - 4.3e-07 28.6 0.0 2.4e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DUF4037 PF13228.6 AAG05184.1 - 0.08 13.7 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) THF_DHG_CYH_C PF02882.19 AAG05185.1 - 2.7e-67 225.1 0.1 3.8e-67 224.6 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AAG05185.1 - 7.7e-40 135.8 0.0 1.1e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 AAG05185.1 - 0.038 12.9 0.2 0.057 12.3 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Beta-lactamase PF00144.24 AAG05186.1 - 2.9e-60 204.3 0.3 4.4e-60 203.7 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 AAG05186.1 - 0.019 14.6 0.0 0.094 12.3 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase enzyme family HATPase_c PF02518.26 AAG05187.1 - 9.9e-22 77.6 0.0 2.5e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAG05187.1 - 1.9e-09 37.8 0.3 6e-09 36.1 0.3 1.9 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 AAG05187.1 - 7.2e-09 35.6 2.0 7.2e-09 35.6 2.0 2.4 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAG05187.1 - 1.3e-06 28.2 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4381 PF14316.6 AAG05187.1 - 7.7e-06 26.2 0.7 0.00049 20.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) HATPase_c_2 PF13581.6 AAG05187.1 - 5e-05 23.2 0.3 0.00026 21.0 0.1 2.2 1 1 2 3 3 3 1 Histidine kinase-like ATPase domain DUF4088 PF13317.6 AAG05187.1 - 0.048 13.2 0.5 0.084 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4088) Baculo_PEP_C PF04513.12 AAG05187.1 - 0.085 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2937 PF11157.8 AAG05187.1 - 0.72 9.6 2.7 0.51 10.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Response_reg PF00072.24 AAG05188.1 - 2.3e-24 85.7 0.0 3.3e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG05188.1 - 2.9e-24 84.9 0.2 6.1e-24 83.9 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal OKR_DC_1_N PF03709.15 AAG05188.1 - 0.04 14.2 0.0 0.078 13.3 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Trigger_N PF05697.13 AAG05189.1 - 1.5e-42 145.3 1.1 1.5e-42 145.3 1.1 3.5 2 1 1 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 AAG05189.1 - 3.2e-37 128.0 19.5 3.3e-36 124.7 8.6 2.9 3 0 0 3 3 3 2 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 AAG05189.1 - 7e-13 48.7 0.0 2e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SurA_N_3 PF13624.6 AAG05189.1 - 0.00033 20.5 2.2 0.00033 20.5 2.2 2.9 3 1 1 4 4 4 1 SurA N-terminal domain DUF4434 PF14488.6 AAG05189.1 - 0.13 12.2 0.1 0.34 10.9 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Vps39_2 PF10367.9 AAG05189.1 - 4.6 7.7 6.5 0.68 10.4 0.6 2.6 3 1 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 CLP_protease PF00574.23 AAG05190.1 - 1.9e-88 295.1 0.0 2.3e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease Plectin PF00681.20 AAG05190.1 - 0.069 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Plectin repeat AAA_2 PF07724.14 AAG05191.1 - 3.9e-50 170.3 0.0 6.8e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 AAG05191.1 - 1.5e-20 72.7 4.2 4.4e-20 71.3 4.2 1.9 1 0 0 1 1 1 1 ClpX C4-type zinc finger ClpB_D2-small PF10431.9 AAG05191.1 - 2.4e-16 59.5 0.3 2.4e-16 59.5 0.3 2.7 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AAG05191.1 - 9.1e-16 58.5 0.1 7.8e-15 55.5 0.0 2.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAG05191.1 - 4.9e-07 29.8 0.1 1.7e-05 24.9 0.1 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG05191.1 - 1e-06 28.3 0.5 8e-05 22.1 0.6 2.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAG05191.1 - 7.2e-06 25.8 0.1 2e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 AAG05191.1 - 7.6e-06 25.2 0.1 1.3e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 AAG05191.1 - 1.2e-05 25.6 0.3 9.2e-05 22.7 0.1 2.5 2 1 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 AAG05191.1 - 0.00054 19.7 0.0 0.098 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 AAG05191.1 - 0.002 18.1 0.1 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAG05191.1 - 0.0022 17.8 0.1 0.0037 17.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAG05191.1 - 0.0023 18.5 0.1 0.028 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 AAG05191.1 - 0.0038 16.3 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 AAG05191.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG05191.1 - 0.0058 17.0 0.0 0.015 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 AAG05191.1 - 0.0069 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 AAG05191.1 - 0.007 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 AAG05191.1 - 0.0074 15.5 0.1 0.02 14.1 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain DEAD PF00270.29 AAG05191.1 - 0.011 15.5 2.0 0.1 12.3 2.0 2.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 AAG05191.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 AAG05191.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 AAG05191.1 - 0.023 15.2 0.0 0.078 13.5 0.0 2.0 2 0 0 2 2 1 0 ABC transporter NACHT PF05729.12 AAG05191.1 - 0.039 13.9 0.1 0.26 11.2 0.0 2.3 3 0 0 3 3 2 0 NACHT domain SMC_N PF02463.19 AAG05191.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG05191.1 - 0.068 13.7 0.3 0.12 12.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAG05191.1 - 0.072 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 AAG05191.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 AAG05191.1 - 0.079 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 AAG05191.1 - 0.091 12.1 3.4 5.8 6.2 0.1 2.8 2 1 1 3 3 3 0 KaiC ResIII PF04851.15 AAG05191.1 - 0.094 12.7 0.3 0.38 10.7 0.1 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_15 PF13175.6 AAG05191.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 AAG05191.1 - 0.12 12.6 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain HBS1_N PF08938.10 AAG05191.1 - 0.14 12.5 0.5 25 5.3 0.0 2.9 3 0 0 3 3 2 0 HBS1 N-terminus RNA_helicase PF00910.22 AAG05191.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_8 PF12780.7 AAG05191.1 - 0.17 11.2 0.0 0.62 9.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 Lon_C PF05362.13 AAG05192.1 - 6.6e-98 326.3 1.7 1.2e-97 325.5 1.7 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 AAG05192.1 - 4.7e-42 144.2 0.1 1.2e-41 142.9 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 AAG05192.1 - 2.2e-19 70.2 0.0 1e-18 68.1 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAG05192.1 - 4.8e-10 39.6 0.0 1.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 AAG05192.1 - 2e-07 30.8 0.1 6.3e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 AAG05192.1 - 1e-06 27.9 0.0 2.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 AAG05192.1 - 9.3e-06 26.1 0.1 0.00015 22.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 AAG05192.1 - 7.5e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 AAG05192.1 - 0.00068 19.4 0.5 0.0023 17.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 AAG05192.1 - 0.001 19.6 1.5 1.4 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAG05192.1 - 0.0027 18.0 0.0 0.028 14.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain SKA2 PF16740.5 AAG05192.1 - 0.0036 17.1 3.7 0.022 14.5 3.2 2.5 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 NACHT PF05729.12 AAG05192.1 - 0.0038 17.2 0.0 0.074 13.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 AAG05192.1 - 0.0085 16.0 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 AAG05192.1 - 0.0089 16.6 0.9 0.021 15.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 AAG05192.1 - 0.0099 15.7 0.0 0.038 13.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAG05192.1 - 0.011 15.8 0.1 0.036 14.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 AAG05192.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AAG05192.1 - 0.019 15.1 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 AAG05192.1 - 0.021 15.3 1.3 0.23 12.0 0.0 2.9 2 1 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 AAG05192.1 - 0.026 14.6 0.4 0.71 10.0 0.0 3.1 2 1 1 3 3 3 0 50S ribosome-binding GTPase ECH_2 PF16113.5 AAG05192.1 - 0.027 14.0 0.4 0.13 11.7 1.2 1.8 2 0 0 2 2 1 0 Enoyl-CoA hydratase/isomerase NB-ARC PF00931.22 AAG05192.1 - 0.03 13.5 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain CENP-R PF06729.12 AAG05192.1 - 0.031 14.2 0.0 0.094 12.6 0.0 1.8 1 0 0 1 1 1 0 Kinetochore component, CENP-R RNA_helicase PF00910.22 AAG05192.1 - 0.038 14.4 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 AAG05192.1 - 0.05 13.8 0.1 0.44 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAG05192.1 - 0.051 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 AAG05192.1 - 0.065 13.0 3.1 0.49 10.2 3.2 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 TsaE PF02367.17 AAG05192.1 - 0.086 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AAG05192.1 - 0.094 12.3 0.4 0.76 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAG05192.1 - 0.1 12.9 0.1 0.4 11.0 0.1 2.0 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 AAG05192.1 - 1.1 9.7 5.0 0.81 10.2 0.1 3.2 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Bac_DNA_binding PF00216.21 AAG05193.1 - 3e-33 113.9 0.1 3.3e-33 113.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAG05193.1 - 2.9e-06 27.4 0.0 3e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAG05193.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AAG05193.1 - 0.021 15.0 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AAG05193.1 - 0.034 14.3 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_1 PF18174.1 AAG05193.1 - 0.14 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 SurA_N_3 PF13624.6 AAG05194.1 - 2.7e-44 150.8 6.7 2.7e-44 150.8 6.7 3.4 3 2 1 5 5 5 1 SurA N-terminal domain SurA_N_2 PF13623.6 AAG05194.1 - 9.1e-33 113.2 1.6 9.1e-33 113.2 1.6 3.4 4 0 0 4 4 4 1 SurA N-terminal domain Rotamase_3 PF13616.6 AAG05194.1 - 1.9e-28 99.4 0.0 1.9e-28 99.4 0.0 2.9 3 0 0 3 3 3 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAG05194.1 - 1e-27 96.9 6.8 1.3e-27 96.5 0.0 3.6 4 0 0 4 4 4 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAG05194.1 - 6.8e-25 88.2 22.8 5.3e-15 56.3 1.6 4.7 2 1 2 4 4 4 4 PPIC-type PPIASE domain SurA_N PF09312.11 AAG05194.1 - 0.0009 19.3 1.5 0.0009 19.3 1.5 2.5 3 0 0 3 3 3 1 SurA N-terminal domain Spc29 PF17082.5 AAG05194.1 - 0.0071 16.2 0.3 0.018 14.9 0.3 1.7 1 0 0 1 1 1 1 Spindle Pole Component 29 PIN_8 PF18476.1 AAG05194.1 - 0.015 15.2 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 PIN like domain SPATA1_C PF15743.5 AAG05194.1 - 8.4 6.4 9.8 22 5.1 0.9 3.1 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus adh_short_C2 PF13561.6 AAG05195.1 - 1.1e-83 280.4 0.2 1.3e-83 280.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG05195.1 - 9.9e-18 64.3 0.0 1.2e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase ABC_tran PF00005.27 AAG05196.1 - 1.2e-61 207.2 0.0 2.4e-29 102.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AAG05196.1 - 5.3e-15 55.5 0.0 1e-07 31.6 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAG05196.1 - 6.1e-14 52.5 5.5 5.2e-06 26.5 0.0 4.0 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AAG05196.1 - 2.1e-13 50.6 0.1 3.8e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_29 PF13555.6 AAG05196.1 - 1.5e-08 34.2 0.2 0.0014 18.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG05196.1 - 4e-07 30.6 4.1 0.0044 17.4 0.2 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AAG05196.1 - 2.8e-06 27.7 6.3 0.03 14.6 0.8 3.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AAG05196.1 - 9.9e-05 22.0 0.1 1.5 8.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 AAG05196.1 - 0.00015 21.7 0.4 0.61 10.0 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 AAG05196.1 - 0.00038 20.0 0.1 0.17 11.4 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region NACHT PF05729.12 AAG05196.1 - 0.00048 20.1 0.2 0.86 9.5 0.0 2.8 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.17 AAG05196.1 - 0.00055 20.1 1.8 0.31 11.1 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain TniB PF05621.11 AAG05196.1 - 0.0006 19.3 0.7 1.7 8.0 0.1 4.0 4 0 0 4 4 4 1 Bacterial TniB protein ATP-synt_ab PF00006.25 AAG05196.1 - 0.00087 19.0 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 AAG05196.1 - 0.0009 19.7 0.0 4 7.9 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 AAG05196.1 - 0.0014 18.9 0.0 0.39 11.0 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 AAG05196.1 - 0.0016 17.7 0.3 0.85 8.8 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain AAA_5 PF07728.14 AAG05196.1 - 0.002 18.1 0.7 0.83 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 AAG05196.1 - 0.0029 17.0 1.4 0.74 9.1 0.1 3.0 3 0 0 3 3 3 1 KaiC AAA_33 PF13671.6 AAG05196.1 - 0.0031 17.7 0.6 0.88 9.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 AAG05196.1 - 0.0033 17.3 0.2 0.4 10.5 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AIG1 PF04548.16 AAG05196.1 - 0.0063 15.9 0.9 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Mg_chelatase PF01078.21 AAG05196.1 - 0.0074 15.7 0.0 0.69 9.2 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_ATPase PF09818.9 AAG05196.1 - 0.0076 15.1 0.0 15 4.2 0.0 3.5 3 1 0 3 3 3 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 AAG05196.1 - 0.011 15.4 2.2 3.2 7.4 0.0 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 AAG05196.1 - 0.012 15.3 1.4 0.99 9.1 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 AAG05196.1 - 0.015 14.7 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 AAG05196.1 - 0.023 15.2 0.0 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAG05196.1 - 0.025 14.3 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAG05196.1 - 0.027 14.8 0.2 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 AAG05196.1 - 0.029 14.3 0.1 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 AAG05196.1 - 0.046 13.8 0.9 14 5.8 0.1 3.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 AAG05196.1 - 0.059 12.6 0.1 4.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 AAG05196.1 - 0.065 13.0 1.2 2 8.1 0.2 2.9 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 AAG05196.1 - 0.11 12.6 0.1 4.4 7.4 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 AAG05196.1 - 0.14 11.9 0.1 7.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 AAG05196.1 - 0.14 12.7 0.3 7.9 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.12 AAG05196.1 - 0.18 11.3 2.8 4.5 6.7 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A32 protein PPV_E1_C PF00519.17 AAG05196.1 - 0.18 10.6 0.0 4.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase GvpD PF07088.11 AAG05196.1 - 0.21 10.2 0.0 2 6.9 0.0 2.1 2 0 0 2 2 2 0 GvpD gas vesicle protein MobB PF03205.14 AAG05196.1 - 0.22 11.4 0.6 2.6 7.9 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B BPD_transp_1 PF00528.22 AAG05197.1 - 9.7e-28 97.2 12.9 9.7e-28 97.2 12.9 1.6 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAG05197.1 - 3.3e-06 27.0 0.3 3.3e-06 27.0 0.3 3.8 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C ABC2_membrane_4 PF12730.7 AAG05197.1 - 1.1 9.2 11.0 0.088 12.8 3.5 2.7 4 0 0 4 4 4 0 ABC-2 family transporter protein BPD_transp_1 PF00528.22 AAG05198.1 - 2.5e-36 125.1 14.1 2.5e-36 125.1 14.1 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF5439 PF17507.2 AAG05198.1 - 0.16 12.2 0.3 0.39 11.0 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5439) SBP_bac_5 PF00496.22 AAG05199.1 - 2.5e-79 267.0 0.6 3.1e-79 266.7 0.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_5 PF00496.22 AAG05200.1 - 1.5e-68 231.5 0.1 2.8e-68 230.6 0.0 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle LysM PF01476.20 AAG05201.1 - 4.7e-42 141.8 0.5 9.9e-14 51.1 0.5 4.5 4 0 0 4 4 4 3 LysM domain SLT PF01464.20 AAG05201.1 - 1.7e-25 88.9 0.0 4.6e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Transglycosylase SLT domain MLTD_N PF06474.12 AAG05201.1 - 3.8e-16 58.9 0.3 1.2e-15 57.3 0.3 2.0 1 0 0 1 1 1 1 MltD lipid attachment motif OapA PF04225.12 AAG05201.1 - 5.3e-07 29.7 0.4 0.00073 19.6 0.1 3.2 3 0 0 3 3 3 2 Opacity-associated protein A LysM-like domain HAGH_C PF16123.5 AAG05202.1 - 2.5e-26 92.0 0.5 3.7e-26 91.4 0.5 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 AAG05202.1 - 4.4e-16 59.5 7.2 1.6e-15 57.6 7.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG05202.1 - 0.0095 15.5 2.1 0.018 14.5 1.7 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_5 PF14597.6 AAG05202.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Methyltransf_11 PF08241.12 AAG05203.1 - 2.2e-06 28.2 0.0 3.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG05203.1 - 0.0078 16.1 0.0 0.016 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG05203.1 - 0.18 12.5 0.0 0.3 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RNase_H PF00075.24 AAG05204.1 - 2.1e-52 177.1 0.0 2.5e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 AAG05204.1 - 0.007 16.2 0.1 0.022 14.6 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_T PF00929.24 AAG05205.1 - 6.4e-39 134.1 0.0 7.7e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAG05205.1 - 3.4e-07 30.4 0.0 5.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like RNase_H_2 PF13482.6 AAG05205.1 - 0.0011 19.0 0.0 0.017 15.1 0.0 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 AAG05205.1 - 0.1 12.3 0.1 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease SnoaL_2 PF12680.7 AAG05206.1 - 4.7e-17 62.5 4.0 5.3e-17 62.3 4.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAG05206.1 - 8.6e-06 26.1 1.3 1.1e-05 25.8 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 AAG05206.1 - 2.8e-05 23.9 0.1 3.5e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase LEH PF07858.12 AAG05206.1 - 0.0069 16.5 0.6 0.0082 16.2 0.6 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain WI12 PF07107.11 AAG05206.1 - 0.03 14.5 0.1 0.048 13.8 0.1 1.5 1 1 0 1 1 1 0 Wound-induced protein WI12 OKR_DC_1 PF01276.20 AAG05207.1 - 2.8e-160 533.6 0.0 4.1e-160 533.1 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 AAG05207.1 - 3.8e-49 166.4 0.0 7.3e-49 165.4 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_N PF03709.15 AAG05207.1 - 3.1e-24 85.4 0.0 6e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Beta_elim_lyase PF01212.21 AAG05207.1 - 1.3e-05 24.6 0.0 0.0058 16.0 0.0 2.8 3 1 0 3 3 3 2 Beta-eliminating lyase Colicin-DNase PF12639.7 AAG05207.1 - 0.2 12.5 0.8 0.35 11.7 0.0 1.8 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin AA_permease_2 PF13520.6 AAG05208.1 - 2.1e-55 188.3 31.5 1.1e-54 185.9 30.8 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAG05208.1 - 1e-30 106.8 22.5 1.4e-30 106.3 22.5 1.1 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 AAG05208.1 - 0.034 13.2 14.4 0.0042 16.2 9.9 1.7 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family Aa_trans PF01490.18 AAG05208.1 - 1.3 7.6 20.5 1.7 7.3 0.1 3.0 2 1 1 3 3 3 0 Transmembrane amino acid transporter protein NhaB PF06450.12 AAG05209.1 - 7.1e-228 757.6 19.7 7.9e-228 757.5 19.7 1.0 1 0 0 1 1 1 1 Bacterial Na+/H+ antiporter B (NhaB) CitMHS PF03600.16 AAG05209.1 - 1.3e-11 44.3 35.2 8.4e-05 21.9 24.9 3.1 1 1 1 2 2 2 2 Citrate transporter DUF2274 PF10038.9 AAG05209.1 - 0.084 13.3 0.2 0.22 12.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) DUF5313 PF17240.2 AAG05209.1 - 0.24 11.9 0.0 0.24 11.9 0.0 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5313) ECH_1 PF00378.20 AAG05210.1 - 3.2e-46 157.7 0.2 4.3e-46 157.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG05210.1 - 2.3e-27 96.4 0.3 2.3e-25 89.8 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase NUDIX PF00293.28 AAG05212.1 - 1.6e-22 80.0 0.0 3.2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 AAG05212.1 - 5.1e-12 46.3 0.1 1.1e-11 45.3 0.1 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 AAG05212.1 - 5.7e-12 45.1 7.6 1.4e-11 43.8 7.6 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 AAG05212.1 - 0.00017 21.5 1.2 0.00036 20.5 1.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon DUF1451 PF07295.11 AAG05212.1 - 0.0012 18.9 2.7 0.0013 18.8 1.5 1.6 2 0 0 2 2 2 1 Zinc-ribbon containing domain OrfB_Zn_ribbon PF07282.11 AAG05212.1 - 0.0061 16.5 2.0 0.012 15.6 2.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HypA PF01155.19 AAG05212.1 - 0.016 15.2 0.2 0.033 14.2 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 AAG05212.1 - 0.056 13.1 1.9 0.12 12.1 1.9 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.6 AAG05212.1 - 0.068 12.6 2.5 3.9 7.0 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAG05212.1 - 0.083 13.0 1.7 0.18 12.0 1.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_4 PF15227.6 AAG05212.1 - 0.11 12.6 1.2 0.23 11.6 1.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc_ribbon_2 PF13240.6 AAG05212.1 - 0.16 11.7 6.4 0.79 9.5 0.6 2.6 3 0 0 3 3 3 0 zinc-ribbon domain GFA PF04828.14 AAG05212.1 - 0.21 11.9 1.7 1.1 9.6 1.7 2.0 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_3 PF13920.6 AAG05212.1 - 0.41 10.5 2.7 0.73 9.7 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AAG05212.1 - 0.62 10.0 2.6 1.2 9.1 2.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF35_N PF12172.8 AAG05212.1 - 1.5 8.8 5.0 1.2 9.0 0.8 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Nudix_N_2 PF14803.6 AAG05212.1 - 1.8 8.5 5.8 10 6.1 5.8 2.2 1 1 0 1 1 1 0 Nudix N-terminal TauE PF01925.19 AAG05213.1 - 2e-40 138.9 31.1 2.4e-40 138.7 31.1 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Phage_holin_3_6 PF07332.11 AAG05214.1 - 3.2 7.8 12.1 0.71 9.9 8.2 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III LysR_substrate PF03466.20 AAG05215.1 - 1.3e-41 142.2 11.8 1.3e-41 142.2 11.8 1.7 2 1 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05215.1 - 1.7e-20 72.7 3.0 7.2e-20 70.7 1.8 2.5 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAG05215.1 - 0.018 14.6 0.0 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding NUDIX PF00293.28 AAG05215.1 - 0.075 13.1 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 NUDIX domain adh_short_C2 PF13561.6 AAG05216.1 - 6.4e-56 189.5 0.4 7.9e-56 189.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG05216.1 - 3e-47 160.6 0.0 3.8e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG05216.1 - 5e-09 36.3 0.6 7e-09 35.8 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG05216.1 - 3.9e-05 23.2 0.5 5.6e-05 22.7 0.0 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAG05216.1 - 0.00022 21.2 0.9 0.00032 20.6 0.9 1.5 1 1 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 AAG05216.1 - 0.00076 19.7 0.2 0.002 18.4 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Glyco_trans_4_4 PF13579.6 AAG05216.1 - 0.011 16.1 4.6 0.032 14.7 0.9 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain YjeF_N PF03853.15 AAG05216.1 - 0.014 15.3 2.7 0.14 12.1 0.1 2.7 2 1 0 2 2 2 0 YjeF-related protein N-terminus DFP PF04127.15 AAG05216.1 - 0.027 14.3 0.4 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.8 AAG05216.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 AAG05216.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LpxK PF02606.14 AAG05216.1 - 0.19 10.8 0.4 4.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase adh_short_C2 PF13561.6 AAG05217.1 - 1.4e-65 221.1 2.7 1.6e-65 220.9 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG05217.1 - 1.1e-51 175.1 2.9 1.3e-51 174.8 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG05217.1 - 2.2e-08 34.2 0.6 3.3e-08 33.7 0.6 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 AAG05217.1 - 0.0015 17.9 0.1 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 AAG05217.1 - 0.0053 16.3 0.1 0.082 12.3 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family APH PF01636.23 AAG05218.1 - 5.4e-50 170.6 0.2 7.8e-50 170.0 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAG05218.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase SCP2 PF02036.17 AAG05219.1 - 1.5e-21 76.7 0.1 1.7e-21 76.6 0.1 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 AAG05219.1 - 7.2e-08 32.7 0.1 8.9e-08 32.5 0.1 1.0 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Antig_Caf1 PF09255.10 AAG05219.1 - 0.075 13.1 0.1 0.095 12.8 0.1 1.1 1 0 0 1 1 1 0 Caf1 Capsule antigen His_Phos_1 PF00300.22 AAG05220.1 - 3e-25 89.1 0.6 1.1e-22 80.7 0.6 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4420 PF14390.6 AAG05220.1 - 0.014 14.7 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) Peptidase_S49_N PF08496.10 AAG05221.1 - 4.8e-54 182.6 1.4 8.1e-54 181.8 1.4 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Peptidase_S49 PF01343.18 AAG05221.1 - 2.3e-44 151.0 0.0 3.5e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 SDH_sah PF01972.16 AAG05221.1 - 0.00041 19.4 0.0 0.00055 19.0 0.0 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase DivIC PF04977.15 AAG05221.1 - 0.18 11.6 1.9 0.81 9.5 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator ADH_zinc_N PF00107.26 AAG05222.1 - 1.8e-10 40.9 0.7 2.8e-10 40.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG05222.1 - 8.2e-08 32.1 0.0 9.9e-06 25.4 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 AAG05222.1 - 0.0011 18.5 0.4 0.0016 17.9 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAG05222.1 - 0.0046 16.5 0.1 0.0075 15.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_N_2 PF16884.5 AAG05222.1 - 0.016 15.1 0.3 0.13 12.2 0.1 2.5 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase NmrA PF05368.13 AAG05222.1 - 0.15 11.6 0.2 0.21 11.1 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 AAG05222.1 - 0.17 11.2 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF4442 PF14539.6 AAG05224.1 - 6.7e-52 175.1 0.1 7.5e-52 174.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) PqqA PF08042.11 AAG05224.1 - 0.35 11.0 2.9 16 5.7 0.1 2.8 2 1 0 2 2 2 0 PqqA family TetR_N PF00440.23 AAG05225.1 - 2.7e-15 55.9 0.0 6.5e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AAG05225.1 - 0.028 14.7 0.2 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_10 PF16295.5 AAG05225.1 - 0.096 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF934 PF06073.12 AAG05226.1 - 4e-46 155.3 0.0 4.9e-46 155.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF934) RecC_C PF17946.1 AAG05226.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.4 1 1 0 1 1 1 0 RecC C-terminal domain NIR_SIR PF01077.22 AAG05227.1 - 7.4e-54 181.6 0.0 7.7e-41 139.2 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAG05227.1 - 2.2e-35 120.3 0.0 2.9e-17 62.3 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Radical_SAM PF04055.21 AAG05228.1 - 7.9e-12 45.9 0.0 1e-10 42.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 AAG05228.1 - 0.00054 20.1 0.0 0.0013 18.8 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain DUF1883 PF08980.10 AAG05229.1 - 2.4e-32 110.7 0.0 3e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1883) tRNA_edit PF04073.15 AAG05230.1 - 4.1e-26 91.5 0.0 5.2e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF469 PF04320.14 AAG05231.1 - 2.6e-32 111.7 0.0 3e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Protein with unknown function (DUF469) Met_synt_B12 PF02965.17 AAG05232.1 - 8.7e-125 415.7 0.0 1.4e-124 415.0 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 AAG05232.1 - 4.1e-79 266.2 0.0 9.6e-79 264.9 0.0 1.7 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 AAG05232.1 - 1.5e-56 191.9 1.1 4.5e-56 190.3 0.3 2.3 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 AAG05232.1 - 7.1e-25 87.2 0.1 2.8e-24 85.4 0.1 2.2 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 AAG05232.1 - 3.5e-20 72.3 0.3 2e-19 69.8 0.3 2.5 1 0 0 1 1 1 1 B12 binding domain OKR_DC_1_N PF03709.15 AAG05232.1 - 0.035 14.4 0.2 9.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain CHAP PF05257.16 AAG05233.1 - 0.0004 20.9 1.3 0.0008 19.9 0.1 1.8 1 1 0 2 2 2 1 CHAP domain NLPC_P60 PF00877.19 AAG05233.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.5 1 1 1 2 2 2 1 NlpC/P60 family CTI PF06934.11 AAG05235.1 - 1.8e-288 958.9 0.0 2.1e-288 958.7 0.0 1.0 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) Cytochrom_C PF00034.21 AAG05235.1 - 0.65 11.2 2.5 22 6.3 2.5 2.6 1 1 0 1 1 1 0 Cytochrome c NifU PF01106.17 AAG05236.1 - 1.3e-21 76.5 0.2 2.6e-21 75.6 0.2 1.5 1 0 0 1 1 1 1 NifU-like domain Fe-S_biosyn PF01521.20 AAG05236.1 - 1.5e-10 41.2 0.0 5.1e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis MFS_1 PF07690.16 AAG05237.1 - 8.2e-22 77.6 50.9 2.3e-12 46.5 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAG05237.1 - 1.1e-05 24.3 6.3 1.1e-05 24.3 6.3 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 AAG05237.1 - 0.82 8.4 20.0 1.2 7.9 6.4 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter Mem_trans PF03547.18 AAG05237.1 - 4.4 5.6 6.7 6.1 5.1 0.2 2.4 2 0 0 2 2 2 0 Membrane transport protein DUF1272 PF06906.11 AAG05238.1 - 9.8e-29 99.2 11.1 1.3e-28 98.9 11.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) NRDD PF13597.6 AAG05238.1 - 1 8.0 3.2 1.3 7.7 3.2 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase zf-RING_4 PF14570.6 AAG05238.1 - 1.3 8.8 13.5 2.2 8.2 13.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HTH_18 PF12833.7 AAG05239.1 - 2.5e-22 78.9 0.3 3.9e-22 78.3 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AAG05239.1 - 3.1e-21 75.9 0.0 4.4e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 AAG05239.1 - 4.1e-15 55.4 0.0 4e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAG05239.1 - 0.014 15.2 0.0 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_3 PF01381.22 AAG05239.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 AAG05239.1 - 0.068 12.6 0.0 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 GGDEF PF00990.21 AAG05240.1 - 2.2e-41 141.3 0.0 3.2e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Chlam_vir PF05475.11 AAG05240.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Pgp3 C-terminal domain DUF2062 PF09835.9 AAG05240.1 - 0.16 11.8 5.8 0.11 12.4 3.7 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) YibE_F PF07907.11 AAG05240.1 - 6.8 6.1 9.8 4 6.9 4.1 2.1 2 0 0 2 2 2 0 YibE/F-like protein LysR_substrate PF03466.20 AAG05242.1 - 1.6e-22 79.9 1.1 7.4e-22 77.7 1.1 2.0 1 1 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05242.1 - 1.2e-19 70.0 1.9 1.2e-19 70.0 1.9 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 AAG05242.1 - 0.0038 17.0 0.1 0.0097 15.7 0.1 1.8 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_30 PF13556.6 AAG05242.1 - 0.022 14.6 0.4 0.05 13.4 0.4 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG05242.1 - 0.045 13.7 0.2 0.14 12.0 0.2 1.9 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AAG05242.1 - 0.049 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 AAG05242.1 - 0.14 11.8 0.2 0.3 10.7 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HPP PF04982.13 AAG05243.1 - 5.5e-30 104.1 11.0 5.5e-30 104.1 11.0 1.9 1 1 1 2 2 2 1 HPP family CBS PF00571.28 AAG05243.1 - 2.9e-26 91.7 0.0 2.1e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain COX1 PF00115.20 AAG05245.1 - 2.2e-112 376.1 62.9 2.7e-112 375.8 62.9 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF808 PF05661.12 AAG05246.1 - 4.7e-118 393.7 15.2 5.6e-118 393.4 15.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF808) PsbX PF06596.11 AAG05246.1 - 0.0007 19.5 3.8 0.0007 19.5 3.8 2.9 3 0 0 3 3 3 1 Photosystem II reaction centre X protein (PsbX) PRA1 PF03208.19 AAG05246.1 - 8.5 6.0 8.0 2.5 7.7 1.7 2.4 2 1 0 2 2 2 0 PRA1 family protein APH_6_hur PF04655.14 AAG05247.1 - 1e-103 346.1 1.4 1.2e-103 345.9 1.4 1.0 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.23 AAG05247.1 - 0.0017 18.4 4.1 0.0017 18.4 4.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 AAG05247.1 - 0.0055 15.9 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Type_III_YscX PF09474.10 AAG05247.1 - 0.011 16.0 0.0 0.042 14.2 0.0 1.9 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) LysR_substrate PF03466.20 AAG05248.1 - 1.4e-45 155.2 3.9 2.2e-45 154.6 3.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05248.1 - 1.9e-20 72.5 1.4 1.9e-20 72.5 1.4 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 AAG05248.1 - 0.022 14.2 0.1 0.054 12.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Crp PF00325.20 AAG05248.1 - 0.034 13.8 0.1 0.36 10.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 AAG05248.1 - 0.045 13.7 1.0 0.086 12.7 0.1 1.9 2 0 0 2 2 2 0 MarR family HTH_30 PF13556.6 AAG05248.1 - 0.065 13.0 1.6 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAG05248.1 - 0.079 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AAG05248.1 - 0.082 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 MarR family MerR_2 PF13591.6 AAG05248.1 - 0.11 12.4 1.8 0.5 10.2 0.1 2.5 2 0 0 2 2 2 0 MerR HTH family regulatory protein HTH_IclR PF09339.10 AAG05248.1 - 0.2 11.5 0.2 0.2 11.5 0.2 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain LCM PF04072.14 AAG05249.1 - 5.4e-20 72.1 0.0 8.4e-19 68.2 0.0 2.3 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase ABC_tran PF00005.27 AAG05250.1 - 5.1e-32 111.3 0.0 7.5e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 AAG05250.1 - 1e-18 67.3 0.6 8.4e-18 64.4 0.1 2.4 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AAG05250.1 - 1.2e-06 28.6 0.1 0.0089 15.9 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAG05250.1 - 0.00014 22.4 0.0 0.00023 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG05250.1 - 0.0021 18.4 0.1 0.0045 17.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG05250.1 - 0.0028 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG05250.1 - 0.0044 17.4 0.7 0.0098 16.3 0.7 1.9 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAG05250.1 - 0.0082 15.6 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAG05250.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 AAG05250.1 - 0.037 13.7 0.0 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG05250.1 - 0.1 12.8 0.0 3.1 8.1 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit BPD_transp_1 PF00528.22 AAG05251.1 - 3e-18 66.2 10.3 4.1e-18 65.8 10.3 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_11 PF13531.6 AAG05252.1 - 7e-45 153.6 5.6 8.1e-45 153.3 5.6 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG05252.1 - 1.2e-13 51.7 7.2 1.2e-08 35.3 2.6 2.0 1 1 1 2 2 2 2 Bacterial extracellular solute-binding protein TetR_C_3 PF08362.11 AAG05253.1 - 5.4e-51 172.3 0.0 7.2e-51 171.9 0.0 1.2 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 AAG05253.1 - 1.1e-14 53.9 0.3 2.2e-14 53.0 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family MerR_1 PF13411.6 AAG05253.1 - 0.054 13.6 0.1 13 6.0 0.0 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein TetR_C_24 PF17932.1 AAG05253.1 - 0.071 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MerR PF00376.23 AAG05253.1 - 0.078 12.8 0.2 9.9 6.0 0.0 2.8 2 0 0 2 2 2 0 MerR family regulatory protein LacI PF00356.21 AAG05253.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family VRR_NUC PF08774.11 AAG05254.1 - 2.3e-33 114.5 0.0 5.1e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain FANC_SAP PF18081.1 AAG05254.1 - 1.5e-13 50.6 7.1 1.5e-13 50.6 7.1 2.5 2 0 0 2 2 2 1 Fanconi anemia-associated nuclease SAP domain Helicase_C_2 PF13307.6 AAG05255.1 - 7e-32 110.9 0.0 1.1e-31 110.3 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 AAG05255.1 - 2.2e-11 43.7 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 AAG05255.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Helical and beta-bridge domain DEAD PF00270.29 AAG05255.1 - 0.00035 20.4 0.0 0.065 13.0 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase T2SSC PF11356.8 AAG05256.1 - 1.1e-12 48.0 0.0 1.8e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Type II secretion system protein C DUF1180 PF06679.12 AAG05256.1 - 0.16 12.4 1.6 0.2 12.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Secretin PF00263.21 AAG05257.1 - 2e-52 177.3 1.0 3.2e-52 176.6 1.0 1.3 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAG05257.1 - 6.5e-36 122.6 8.8 8e-14 51.8 0.1 3.6 3 0 0 3 3 3 3 Bacterial type II/III secretion system short domain PP-binding PF00550.25 AAG05258.1 - 2.5e-14 53.4 0.3 2.8e-14 53.2 0.3 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ribosomal_L12_N PF16320.5 AAG05258.1 - 0.0019 17.8 2.4 0.0025 17.5 1.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF1493 PF07377.12 AAG05258.1 - 0.015 15.8 0.2 0.017 15.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.9 AAG05258.1 - 0.083 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S Peptidase_M23 PF01551.22 AAG05260.1 - 1.3e-11 44.5 0.1 2.7e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M23 EcsC PF12787.7 AAG05261.1 - 2.7e-40 138.6 1.1 1.4e-39 136.3 1.1 1.8 1 1 0 1 1 1 1 EcsC protein family DUF2333 PF10095.9 AAG05261.1 - 0.036 13.1 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) CorA PF01544.18 AAG05262.1 - 2.1e-50 171.7 0.1 2.4e-50 171.5 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Big_6 PF17936.1 AAG05263.1 - 0 1212.4 355.1 2.8e-20 72.4 5.6 27.5 28 1 0 28 28 28 24 Bacterial Ig domain bMG3 PF11974.8 AAG05263.1 - 1.2e-48 163.4 73.5 0.017 15.1 0.2 20.4 21 0 0 21 21 21 18 Bacterial alpha-2-macroglobulin MG3 domain SdrD_B PF17210.3 AAG05263.1 - 7.3e-20 71.3 71.6 1 9.6 0.2 18.9 11 3 5 19 19 19 10 SdrD B-like domain Peptidase_Mx1 PF15890.5 AAG05263.1 - 8.2e-08 32.0 10.5 38 3.6 0.0 13.2 18 0 0 18 18 18 0 Putative zinc-binding metallo-peptidase Big_10 PF17964.1 AAG05263.1 - 5.7e-07 29.7 70.0 1.5 8.7 0.6 16.9 3 2 15 18 18 18 8 Bacterial Ig domain BRK PF07533.16 AAG05263.1 - 3.3e-05 23.4 7.4 84 2.9 0.0 9.9 11 0 0 11 11 11 0 BRK domain FG-GAP PF01839.23 AAG05263.1 - 0.00018 21.6 0.8 0.00018 21.6 0.8 6.1 5 0 0 5 5 5 3 FG-GAP repeat PUA_3 PF17785.1 AAG05263.1 - 0.00073 19.3 37.1 72 3.3 0.0 17.1 20 1 1 21 21 21 0 PUA-like domain AOC_like PF18678.1 AAG05263.1 - 0.0012 18.5 23.2 18 4.9 0.1 11.3 8 3 6 14 14 14 0 Allene oxide cyclase barrel like domain CarboxypepD_reg PF13620.6 AAG05263.1 - 0.17 12.1 237.9 1 9.6 1.5 27.3 16 5 10 27 27 27 0 Carboxypeptidase regulatory-like domain OEP PF02321.18 AAG05264.1 - 3.6e-40 137.8 18.0 2.8e-22 79.4 1.0 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein ABC_tran PF00005.27 AAG05265.1 - 2.6e-30 105.7 0.0 4.8e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAG05265.1 - 1.9e-18 67.1 5.5 2.6e-18 66.7 5.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 AAG05265.1 - 3.8e-08 33.5 0.1 0.00057 19.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG05265.1 - 2.1e-06 27.3 0.0 0.00021 20.8 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG05265.1 - 0.011 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoR PF11808.8 AAG05265.1 - 0.04 14.3 0.3 0.16 12.4 0.3 2.1 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR AAA_28 PF13521.6 AAG05265.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAG05265.1 - 0.074 13.4 2.0 0.089 13.2 0.3 2.0 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 AAG05265.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AAG05265.1 - 0.19 12.2 0.0 0.3 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain HlyD_3 PF13437.6 AAG05266.1 - 3.3e-19 69.5 3.3 6.2e-17 62.2 0.2 3.2 3 1 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAG05266.1 - 2.5e-08 33.4 0.9 3.1e-06 26.6 0.9 2.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG05266.1 - 5.2e-08 32.6 0.8 3.1e-06 26.9 0.1 3.2 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG05266.1 - 3.5e-06 26.7 0.4 0.013 15.3 0.1 3.3 3 0 0 3 3 3 2 Biotin-requiring enzyme HlyD PF00529.20 AAG05266.1 - 7.7e-06 25.7 0.1 1.2e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Atg14 PF10186.9 AAG05266.1 - 6 5.9 6.2 8.6 5.3 6.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HD_3 PF13023.6 AAG05267.1 - 9.1e-41 139.5 0.0 1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 AAG05267.1 - 2.4e-13 50.2 0.0 3.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AAG05267.1 - 0.00023 21.4 1.8 0.00052 20.2 1.8 1.6 1 1 0 1 1 1 1 HD domain HTH_31 PF13560.6 AAG05268.1 - 2.7e-08 34.1 9.6 2.7e-08 34.1 9.6 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAG05268.1 - 1.1e-06 28.5 0.5 2.8e-06 27.3 0.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 AAG05268.1 - 0.0024 17.6 1.7 0.0073 16.1 1.5 2.1 1 1 0 1 1 1 1 Homeodomain-like domain YdaS_antitoxin PF15943.5 AAG05268.1 - 0.0047 16.8 0.5 0.025 14.5 0.1 2.1 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PAS_4 PF08448.10 AAG05268.1 - 0.005 17.1 0.1 0.014 15.7 0.0 1.7 1 1 1 2 2 2 1 PAS fold HTH_28 PF13518.6 AAG05268.1 - 0.019 15.1 0.3 0.064 13.4 0.3 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 AAG05268.1 - 0.043 13.6 0.2 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease Cro PF09048.10 AAG05268.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Cro HTH_37 PF13744.6 AAG05268.1 - 0.083 12.9 0.1 0.25 11.3 0.0 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain Phage_CII PF05269.11 AAG05268.1 - 0.089 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CII protein HTH_Tnp_1_2 PF13022.6 AAG05268.1 - 0.19 11.9 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Ald_Xan_dh_C2 PF02738.18 AAG05269.1 - 5.5e-68 229.8 4.9 1.6e-30 106.1 0.0 3.1 2 1 0 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAG05269.1 - 0.0055 17.0 0.0 0.14 12.5 0.0 2.6 1 1 1 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain TAT_signal PF10518.9 AAG05269.1 - 0.0089 15.8 0.5 0.0089 15.8 0.5 3.1 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer2_2 PF01799.20 AAG05270.1 - 2.2e-26 91.7 0.4 2.2e-26 91.7 0.4 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAG05270.1 - 8.8e-09 35.2 0.2 8.8e-09 35.2 0.2 1.8 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAG05270.1 - 0.00023 21.1 0.1 0.00035 20.5 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAG05270.1 - 0.0058 16.7 2.5 0.015 15.4 2.0 2.1 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Multi_Drug_Res PF00893.19 AAG05271.1 - 5.3e-29 100.7 8.3 6.9e-29 100.4 8.3 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAG05271.1 - 0.024 14.8 17.4 0.037 14.2 17.4 1.3 1 1 0 1 1 1 0 EamA-like transporter family Oxidored_q4 PF00507.19 AAG05272.1 - 1.1e-29 102.5 0.1 1.5e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF3687 PF12459.8 AAG05272.1 - 0.082 12.4 0.2 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein COX7C PF02935.16 AAG05272.1 - 2.2 8.6 5.2 0.58 10.5 1.1 2.1 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIIc HTH_3 PF01381.22 AAG05273.1 - 9.2e-13 48.0 0.4 1.6e-12 47.3 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAG05273.1 - 8.9e-12 45.2 4.5 8.9e-12 45.2 4.5 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG05273.1 - 4.5e-10 39.4 0.0 6.7e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAG05273.1 - 0.00014 22.2 0.1 0.00021 21.7 0.1 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AAG05273.1 - 0.00027 20.7 0.8 0.00044 20.1 0.8 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAG05273.1 - 0.00034 20.5 0.1 0.00062 19.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAG05273.1 - 0.00042 19.8 0.2 0.00079 18.9 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 AAG05273.1 - 0.002 18.0 0.6 0.0056 16.6 0.2 2.0 2 0 0 2 2 2 1 MarR family Rab_bind PF16704.5 AAG05273.1 - 0.032 14.2 0.4 0.055 13.5 0.4 1.3 1 0 0 1 1 1 0 Rab binding domain HTH_6 PF01418.17 AAG05273.1 - 0.039 13.9 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_24 PF13412.6 AAG05273.1 - 0.074 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAG05273.1 - 0.16 11.8 1.4 0.21 11.4 0.3 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain TetR_N PF00440.23 AAG05273.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Acetyltransf_1 PF00583.25 AAG05274.1 - 8.2e-12 45.4 0.0 9.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG05274.1 - 3.2e-11 43.3 0.0 4.5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG05274.1 - 8.4e-09 35.7 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG05274.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAG05274.1 - 0.0027 17.8 0.0 0.056 13.5 0.0 2.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain RHH_1 PF01402.21 AAG05274.1 - 0.0066 16.4 4.7 0.27 11.2 0.1 2.8 2 1 0 2 2 2 2 Ribbon-helix-helix protein, copG family PanZ PF12568.8 AAG05274.1 - 0.0083 15.9 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ DNA_pol_B PF00136.21 AAG05275.1 - 5.9e-40 137.3 0.0 3.7e-39 134.7 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AAG05275.1 - 7.2e-13 48.4 0.0 2.5e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 AAG05275.1 - 9e-05 21.5 0.0 0.015 14.2 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral P63C PF10546.9 AAG05275.1 - 0.17 12.5 0.2 0.36 11.4 0.2 1.5 1 0 0 1 1 1 0 P63C domain Phospholip_A2_3 PF09056.11 AAG05276.1 - 0.14 12.8 2.4 0.34 11.6 2.4 1.5 1 1 0 1 1 1 0 Prokaryotic phospholipase A2 Abhydrolase_6 PF12697.7 AAG05277.1 - 2.6e-05 25.0 0.6 4.5e-05 24.2 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Defensin_propep PF00879.18 AAG05277.1 - 0.039 14.2 0.1 0.085 13.1 0.1 1.6 1 0 0 1 1 1 0 Defensin propeptide Lipase_3 PF01764.25 AAG05277.1 - 0.045 13.6 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) GST_N_3 PF13417.6 AAG05279.1 - 1.9e-15 57.0 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG05279.1 - 4.1e-12 46.2 0.0 6.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAG05279.1 - 1.1e-11 44.9 0.0 1.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG05279.1 - 4.2e-06 26.9 0.0 6.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAG05279.1 - 0.00027 20.9 0.1 0.00098 19.1 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG05279.1 - 0.002 18.3 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF402 PF04167.13 AAG05281.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF402) Penicil_amidase PF01804.18 AAG05282.1 - 8.5e-198 659.5 4.4 1.1e-197 659.2 4.4 1.0 1 0 0 1 1 1 1 Penicillin amidase 2OG-FeII_Oxy_3 PF13640.6 AAG05283.1 - 2.6e-10 41.0 0.0 4.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 AAG05283.1 - 0.0017 18.8 0.1 0.0054 17.2 0.1 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Arg_Hydrox PF05118.15 AAG05283.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase 2OG-FeII_Oxy_4 PF13661.6 AAG05283.1 - 0.033 14.9 0.0 0.066 13.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1235 PF06822.12 AAG05283.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1235) Thioesterase PF00975.20 AAG05283.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain FA_desaturase PF00487.24 AAG05284.1 - 1.2e-07 31.8 25.7 1.2e-07 31.8 25.7 2.7 1 1 1 2 2 2 1 Fatty acid desaturase PDR_CDR PF06422.12 AAG05284.1 - 0.42 10.6 2.1 0.96 9.4 0.1 2.3 2 0 0 2 2 2 0 CDR ABC transporter Ribosomal_L29 PF00831.23 AAG05285.1 - 0.065 13.2 0.1 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L29 protein FA_hydroxylase PF04116.13 AAG05286.1 - 1.6e-28 99.7 14.0 1.6e-28 99.7 14.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Autoind_bind PF03472.15 AAG05287.1 - 2.8e-36 124.2 0.0 3.7e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AAG05287.1 - 5.2e-16 57.9 0.5 7.8e-16 57.4 0.5 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AAG05287.1 - 0.003 17.0 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAG05287.1 - 0.0031 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 PHZA_PHZB PF03284.13 AAG05288.1 - 9.7e-89 294.9 0.6 1.2e-88 294.6 0.6 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B SnoaL_2 PF12680.7 AAG05288.1 - 5.9e-08 33.3 0.0 8.8e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAG05288.1 - 0.00026 20.8 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PHZA_PHZB PF03284.13 AAG05289.1 - 7.5e-91 301.7 0.5 9e-91 301.5 0.5 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B SnoaL_2 PF12680.7 AAG05289.1 - 1.5e-05 25.5 0.0 2.3e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAG05289.1 - 0.002 17.9 0.0 0.0057 16.5 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Adeno_GP19K PF04881.13 AAG05289.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus GP19K DAHP_synth_2 PF01474.16 AAG05290.1 - 2.7e-127 424.9 0.0 6.4e-78 262.2 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family Isochorismatase PF00857.20 AAG05291.1 - 3.2e-35 121.9 0.0 3.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Chorismate_bind PF00425.18 AAG05292.1 - 4.4e-47 160.8 0.0 5.9e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 AAG05292.1 - 1.2e-25 90.4 0.0 1.7e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PhzC-PhzF PF02567.16 AAG05293.1 - 2.8e-85 286.2 0.0 3.2e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HIT PF01230.23 AAG05294.1 - 0.19 12.5 0.0 0.45 11.3 0.0 1.6 1 1 0 1 1 1 0 HIT domain PAF-AH_p_II PF03403.13 AAG05295.1 - 2.4e-07 29.6 0.0 6.3e-06 24.9 0.0 2.3 2 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 AAG05295.1 - 0.0011 18.0 0.0 0.0061 15.5 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 AAG05295.1 - 0.016 14.5 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acyl_transf_3 PF01757.22 AAG05295.1 - 0.35 9.9 6.6 0.61 9.1 6.6 1.3 1 0 0 1 1 1 0 Acyltransferase family MFS_1 PF07690.16 AAG05296.1 - 2e-35 122.4 55.1 8.4e-22 77.6 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM PF03929.16 AAG05297.1 - 8.7e-55 186.4 3.7 1e-54 186.2 3.7 1.0 1 0 0 1 1 1 1 PepSY-associated TM region DUF1129 PF06570.11 AAG05297.1 - 0.048 13.1 1.5 0.098 12.1 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Adeno_E3B PF03376.14 AAG05297.1 - 0.17 12.1 0.8 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E3B protein Cytochrom_B561 PF03188.16 AAG05297.1 - 4.6 7.4 6.4 7.6 6.7 0.9 2.6 3 1 0 3 3 3 0 Eukaryotic cytochrome b561 TonB_dep_Rec PF00593.24 AAG05298.1 - 1.1e-41 144.3 17.2 1.7e-41 143.6 16.1 1.8 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG05298.1 - 5.8e-17 62.2 0.1 2.1e-16 60.4 0.1 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG05298.1 - 1.8e-07 30.9 0.0 3.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AAG05299.1 - 3.1e-20 72.6 0.1 4.9e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG05299.1 - 7e-15 54.6 12.9 7e-15 54.6 12.9 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) Sigma70_r4_2 PF08281.12 AAG05300.1 - 3e-17 62.0 1.0 2.6e-16 59.0 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG05300.1 - 5.6e-15 54.9 1.2 9.7e-15 54.1 1.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG05300.1 - 2e-09 36.8 0.1 5.6e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG05300.1 - 0.00013 21.7 0.1 0.00042 20.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AAG05300.1 - 0.00036 20.5 0.1 0.00055 19.9 0.1 1.5 1 1 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 AAG05300.1 - 0.0022 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GerE PF00196.19 AAG05300.1 - 0.0067 15.9 0.0 0.064 12.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_31 PF13560.6 AAG05300.1 - 0.0096 16.2 4.4 0.18 12.2 4.4 2.6 1 1 0 1 1 1 1 Helix-turn-helix domain TnsD PF15978.5 AAG05300.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_11 PF08279.12 AAG05300.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain DUF2599 PF10783.9 AAG05302.1 - 6.5e-28 97.2 0.5 1.5e-27 96.1 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2599) PucR PF07905.11 AAG05303.1 - 1.7e-31 108.9 0.0 3.6e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 AAG05303.1 - 1.4e-19 69.6 1.0 1.4e-19 69.6 1.0 2.6 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 AAG05303.1 - 0.0029 17.5 0.2 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PreAtp-grasp PF18604.1 AAG05303.1 - 0.11 12.1 0.2 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Pre ATP-grasp domain GGDEF_2 PF17853.1 AAG05303.1 - 0.47 10.7 13.5 0.93 9.8 5.0 3.8 2 1 0 3 3 3 0 GGDEF-like domain Trp_Tyr_perm PF03222.13 AAG05304.1 - 2.6e-35 122.2 23.0 5.7e-35 121.1 23.0 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 AAG05304.1 - 2.8e-11 42.8 15.8 4.6e-11 42.1 15.8 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cupin_3 PF05899.12 AAG05305.1 - 1.3e-26 92.1 0.3 1.7e-26 91.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AAG05305.1 - 2.3e-06 27.2 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AAG05305.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Cupin DAO PF01266.24 AAG05306.1 - 8.6e-54 183.4 4.9 1e-53 183.2 4.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG05306.1 - 2.1e-05 23.9 0.3 4.1e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 AAG05306.1 - 0.00011 21.6 0.1 0.0054 16.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG05306.1 - 0.00031 20.9 0.1 0.00079 19.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAG05306.1 - 0.0029 16.4 0.8 0.17 10.6 0.1 2.6 2 1 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 AAG05306.1 - 0.012 15.0 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG05306.1 - 0.012 14.7 6.2 0.063 12.4 6.2 1.9 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 AAG05306.1 - 0.061 13.9 0.0 0.28 11.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAG05306.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 AAG05306.1 - 0.1 12.6 2.3 2.6 8.0 0.2 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 AAG05306.1 - 0.17 10.7 0.2 0.32 9.8 0.2 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Mqo PF06039.15 AAG05306.1 - 0.22 10.0 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Radical_SAM PF04055.21 AAG05307.1 - 6.9e-14 52.6 0.0 1.8e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAG05307.1 - 8e-09 35.9 0.0 1.3e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain NRDD PF13597.6 AAG05308.1 - 3.2e-168 561.0 0.0 4.1e-168 560.7 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase ATP-cone PF03477.16 AAG05308.1 - 1.1e-20 74.0 0.0 4.7e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain Methyltransf_25 PF13649.6 AAG05309.1 - 7.7e-10 39.4 0.1 3.4e-09 37.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_19 PF04672.12 AAG05309.1 - 7.1e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_12 PF08242.12 AAG05309.1 - 5.5e-06 27.1 0.0 1.1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG05309.1 - 8.2e-06 25.5 0.0 3.2e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAG05309.1 - 1.4e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG05309.1 - 2.6e-05 24.8 0.0 0.00019 22.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 AAG05309.1 - 8.1e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_23 PF13489.6 AAG05309.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAG05309.1 - 0.012 15.7 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 AAG05309.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TonB_dep_Rec PF00593.24 AAG05310.1 - 2.2e-61 209.2 10.4 2.8e-61 208.8 10.4 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG05310.1 - 1.5e-26 93.1 0.1 3.7e-26 91.8 0.1 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG05310.1 - 1.1e-08 34.5 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family CobN-Mg_chel PF02514.16 AAG05311.1 - 1.4e-288 960.2 0.0 1.6e-288 960.0 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase MotA_ExbB PF01618.16 AAG05312.1 - 7.8e-07 28.9 0.0 9.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF2149 PF09919.9 AAG05313.1 - 2.8e-26 91.6 0.1 3.2e-26 91.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2149) YcaO_C PF18381.1 AAG05314.1 - 4e-73 244.9 0.5 5.9e-73 244.4 0.5 1.2 1 0 0 1 1 1 1 YcaO cyclodehydratase C-terminal domain YcaO PF02624.16 AAG05314.1 - 6e-71 239.4 0.0 9.8e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding Meth_synt_2 PF01717.18 AAG05315.1 - 7.2e-159 528.3 0.0 7.2e-154 511.9 0.0 2.8 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 AAG05315.1 - 9e-127 422.9 0.0 4.2e-118 394.4 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Acetyltransf_3 PF13302.7 AAG05316.1 - 5.1e-18 66.1 0.0 6.2e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG05316.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AAG05316.1 - 3.4e-06 27.3 0.0 3.5e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG05316.1 - 1.2e-05 25.1 0.0 1.7e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF5594 PF18057.1 AAG05316.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5594) FR47 PF08445.10 AAG05316.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein MCPsignal PF00015.21 AAG05318.1 - 6e-33 114.1 18.0 6e-33 114.1 18.0 2.8 1 1 2 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.7 AAG05318.1 - 1.2e-29 102.6 0.0 2.2e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAG05318.1 - 2.6e-28 98.4 0.1 8.5e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AAG05318.1 - 2.9e-25 88.4 0.0 6.9e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAG05318.1 - 1e-18 67.4 0.0 2.8e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAG05318.1 - 3.9e-08 33.1 0.0 0.00035 20.5 0.0 2.7 2 0 0 2 2 2 2 PAS domain Cache_3-Cache_2 PF17201.4 AAG05318.1 - 0.0089 15.3 2.2 3.6 6.8 0.0 3.1 3 1 0 3 3 3 2 Cache 3/Cache 2 fusion domain sCache_3_3 PF17202.4 AAG05318.1 - 0.02 15.3 0.0 6.3 7.3 0.0 2.8 2 0 0 2 2 2 0 Single cache domain 3 Csm1_N PF18504.1 AAG05318.1 - 0.099 13.0 3.5 0.29 11.5 0.8 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain YcgR PF07317.12 AAG05318.1 - 0.51 10.2 3.6 15 5.5 0.1 3.1 3 1 0 3 3 3 0 Flagellar regulator YcgR DUF1664 PF07889.12 AAG05318.1 - 0.63 10.1 6.4 6.2 6.9 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 AAG05318.1 - 4.2 7.8 9.7 0.65 10.4 1.6 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 AAG05318.1 - 4.6 7.4 7.5 6 7.0 1.2 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Fer2_2 PF01799.20 AAG05319.1 - 5.8e-32 109.5 0.5 5.8e-32 109.5 0.5 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAG05319.1 - 3.7e-07 30.0 0.1 3.7e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAG05319.1 - 0.00019 21.4 0.1 0.00034 20.6 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_5 PF00941.21 AAG05320.1 - 3.8e-50 169.9 0.0 5.3e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAG05320.1 - 7.6e-15 54.9 0.2 1.4e-14 54.1 0.2 1.5 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C2 PF02738.18 AAG05321.1 - 5e-109 365.2 0.3 6.3e-109 364.9 0.3 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAG05321.1 - 2e-17 63.5 0.0 1.6e-16 60.6 0.0 2.4 3 0 0 3 3 3 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain DUF4354 PF14263.6 AAG05322.1 - 1.8e-48 163.5 0.0 2e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4354) DUF4352 PF11611.8 AAG05322.1 - 0.058 13.7 0.0 0.072 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) UvrD_C_2 PF13538.6 AAG05323.1 - 1.6e-06 27.8 0.3 0.001 18.8 0.3 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 AAG05323.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain RE_AccI PF09545.10 AAG05323.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 AccI restriction endonuclease HTH_Tnp_1 PF01527.20 AAG05325.1 - 9.3e-20 70.7 0.6 1.3e-19 70.3 0.6 1.2 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAG05325.1 - 0.00084 19.4 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG05325.1 - 0.00091 18.9 0.4 0.0071 16.1 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MAD PF05557.13 AAG05325.1 - 0.0026 16.2 0.6 0.0031 16.0 0.6 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein M PF02370.16 AAG05325.1 - 0.0038 17.6 2.4 1.6 9.5 0.3 2.5 1 1 0 2 2 2 2 M protein repeat TSC22 PF01166.18 AAG05325.1 - 0.0075 16.6 1.4 0.011 16.1 0.7 1.6 2 0 0 2 2 2 1 TSC-22/dip/bun family Shugoshin_N PF07558.11 AAG05325.1 - 0.0081 16.0 1.0 0.016 15.1 1.0 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region VasL PF12486.8 AAG05325.1 - 0.0081 16.0 0.4 0.011 15.5 0.4 1.2 1 0 0 1 1 1 1 Type VI secretion system, EvfB, or VasL HTH_29 PF13551.6 AAG05325.1 - 0.012 15.6 0.2 0.025 14.6 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix BLOC1_2 PF10046.9 AAG05325.1 - 0.029 14.7 0.3 0.043 14.1 0.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 AAG05325.1 - 0.032 14.5 3.0 0.032 14.5 3.0 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain COG2 PF06148.11 AAG05325.1 - 0.095 12.8 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.15 AAG05325.1 - 0.16 11.8 4.6 0.34 10.7 4.6 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.6 AAG05325.1 - 0.18 12.3 3.7 0.41 11.1 3.7 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.15 AAG05325.1 - 0.33 11.1 5.8 0.43 10.7 3.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper rve PF00665.26 AAG05326.1 - 6.4e-33 113.5 0.3 1.2e-32 112.5 0.3 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAG05326.1 - 3e-14 53.4 0.1 4.6e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 DDE domain HTH_21 PF13276.6 AAG05326.1 - 7.1e-14 51.7 0.2 1.8e-13 50.4 0.2 1.7 1 0 0 1 1 1 1 HTH-like domain rve_3 PF13683.6 AAG05326.1 - 1.7e-11 43.7 1.0 1e-10 41.2 0.6 2.4 3 0 0 3 3 3 1 Integrase core domain rve_2 PF13333.6 AAG05326.1 - 0.039 14.1 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain HTH_33 PF13592.6 AAG05326.1 - 0.082 12.6 0.8 0.27 10.9 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn helix AAA_15 PF13175.6 AAG05327.1 - 3.9e-30 105.8 0.0 5.4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAG05327.1 - 2e-06 27.8 0.8 6.3e-06 26.2 0.8 1.9 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system HTH_18 PF12833.7 AAG05327.1 - 0.048 13.9 0.4 0.3 11.4 0.4 2.4 1 1 0 1 1 1 0 Helix-turn-helix domain Catalase PF00199.19 AAG05328.1 - 5.6e-12 45.5 0.1 2e-11 43.6 0.1 1.9 1 1 0 1 1 1 1 Catalase Cytochrome_CBB3 PF13442.6 AAG05329.1 - 2e-09 37.7 0.4 0.0036 17.6 0.1 3.6 3 0 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG05329.1 - 1.3e-08 35.8 0.0 0.0018 19.4 0.1 4.0 3 1 0 3 3 3 1 Cytochrome c DUF1924 PF09086.11 AAG05329.1 - 0.013 15.9 0.0 0.44 10.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) DUF2756 PF10956.8 AAG05329.1 - 0.014 15.9 0.1 0.029 14.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Cytochrom_C550 PF14495.6 AAG05329.1 - 0.023 14.4 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c-550 domain Haem_bd PF14376.6 AAG05329.1 - 0.16 11.9 0.0 9.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Haem-binding domain Nsp2a_N PF17896.1 AAG05330.1 - 0.086 12.0 0.0 0.097 11.8 0.0 1.0 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain DUF3335 PF11814.8 AAG05331.1 - 1.3e-91 305.6 0.0 1.8e-91 305.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase_C39 like family Acetyltransf_1 PF00583.25 AAG05331.1 - 1.1e-16 61.1 0.1 2.1e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG05331.1 - 4.1e-12 46.1 0.0 6.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG05331.1 - 1.8e-10 41.1 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C39_2 PF13529.6 AAG05331.1 - 6.5e-05 23.5 0.0 0.29 11.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family FR47 PF08445.10 AAG05331.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AAG05331.1 - 0.00056 20.6 0.0 0.0014 19.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C70 PF12385.8 AAG05331.1 - 0.0011 19.0 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 Acetyltransf_CG PF14542.6 AAG05331.1 - 0.0037 17.4 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AAG05331.1 - 0.0057 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG05331.1 - 0.033 13.9 0.0 0.096 12.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_C39 PF03412.15 AAG05331.1 - 0.065 13.0 0.0 18 5.2 0.0 2.6 2 1 0 2 2 2 0 Peptidase C39 family Acetyltransf_9 PF13527.7 AAG05331.1 - 0.085 12.9 0.0 0.4 10.8 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RLAN PF14401.6 AAG05332.1 - 6.1e-49 165.5 0.0 9.4e-49 164.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain RimK PF08443.11 AAG05332.1 - 1.9e-09 37.4 0.0 1.2e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAG05332.1 - 2.8e-06 27.0 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AAG05332.1 - 9.9e-06 25.7 0.0 3.9e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AAG05332.1 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAG05332.1 - 0.0053 16.4 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AAG05332.1 - 0.0055 16.0 0.0 0.03 13.6 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp R2K_2 PF18299.1 AAG05332.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Sigma54_activat PF00158.26 AAG05333.1 - 3.9e-71 238.2 0.0 5.1e-71 237.8 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG05333.1 - 3.4e-23 82.3 0.0 7.4e-23 81.2 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG05333.1 - 4.2e-08 32.8 0.0 3.3e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAG05333.1 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_23 PF13384.6 AAG05333.1 - 3.2e-05 23.6 0.1 0.00017 21.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 AAG05333.1 - 0.00019 21.4 0.4 0.00068 19.6 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.7 AAG05333.1 - 0.0004 20.5 0.1 0.0037 17.4 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain AAA PF00004.29 AAG05333.1 - 0.0017 18.8 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG05333.1 - 0.002 18.6 0.3 0.0049 17.3 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain HTH_28 PF13518.6 AAG05333.1 - 0.0049 17.0 0.0 0.024 14.7 0.0 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_3 PF07726.11 AAG05333.1 - 0.0051 16.7 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAG05333.1 - 0.0086 15.5 0.1 0.44 9.9 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI HTH_1 PF00126.27 AAG05333.1 - 0.046 13.7 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family AAA_7 PF12775.7 AAG05333.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 AAG05333.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 KaiC HTH_22 PF13309.6 AAG05333.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_7 PF02796.15 AAG05333.1 - 0.16 12.1 0.0 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase AAA_2 PF07724.14 AAG05333.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Peripla_BP_4 PF13407.6 AAG05334.1 - 1.1e-55 189.0 10.2 1.3e-55 188.8 10.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAG05334.1 - 9.6e-27 94.1 1.5 1.1e-26 93.9 1.5 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAG05334.1 - 1.6e-11 44.9 0.1 3.2e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Mannitol_dh PF01232.23 AAG05334.1 - 0.058 13.5 0.1 0.16 12.1 0.1 1.9 1 1 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain ABC_tran PF00005.27 AAG05335.1 - 1.6e-45 155.0 0.0 3e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAG05335.1 - 1.5e-05 25.0 0.4 0.1 12.4 0.3 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAG05335.1 - 0.00075 19.2 0.1 0.026 14.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAG05335.1 - 0.0064 16.2 3.7 0.88 9.2 1.3 3.7 3 1 0 3 3 3 1 AAA domain TsaE PF02367.17 AAG05335.1 - 0.011 15.7 0.4 0.87 9.6 0.2 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 AAG05335.1 - 0.013 16.0 0.2 0.049 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAG05335.1 - 0.057 13.8 6.4 2.4 8.5 0.5 3.1 2 2 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 AAG05335.1 - 0.15 12.4 1.6 1.6 9.0 0.1 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 AAG05335.1 - 0.19 11.6 2.0 5.3 6.9 0.1 2.8 3 0 0 3 3 3 0 NTPase AAA_25 PF13481.6 AAG05335.1 - 0.19 11.2 1.9 5.4 6.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 AAG05335.1 - 0.39 9.3 0.3 0.57 8.8 0.3 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAG05335.1 - 0.51 9.9 1.3 7.7 6.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain BPD_transp_2 PF02653.16 AAG05336.1 - 1.1e-47 162.5 40.1 1.1e-47 162.5 40.1 1.5 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component FeoB_associated PF12669.7 AAG05336.1 - 0.48 10.9 0.1 0.48 10.9 0.1 3.7 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein Peripla_BP_3 PF13377.6 AAG05337.1 - 6e-43 147.0 0.1 4.7e-42 144.1 0.1 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAG05337.1 - 4.9e-37 127.9 0.0 6.6e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AAG05337.1 - 6.9e-17 61.0 0.9 1.5e-16 59.9 0.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AAG05337.1 - 2e-15 57.0 0.0 3.2e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 AAG05337.1 - 0.044 13.9 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix PfkB PF00294.24 AAG05338.1 - 1e-74 251.6 1.2 1.2e-74 251.4 1.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AAG05338.1 - 2e-10 40.5 0.0 4.1e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Glyco_trans_1_4 PF13692.6 AAG05338.1 - 0.073 13.5 0.5 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Phenol_MetA_deg PF13557.6 AAG05339.1 - 5.7e-09 36.3 10.7 4.1e-06 26.9 2.1 3.3 1 1 1 2 2 2 2 Putative MetA-pathway of phenol degradation Autotransporter PF03797.19 AAG05339.1 - 9.8e-05 22.1 8.7 0.046 13.4 0.0 3.3 3 1 0 3 3 3 3 Autotransporter beta-domain Phage_Nu1 PF07471.12 AAG05339.1 - 0.013 15.3 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 CCD48 PF15799.5 AAG05339.1 - 0.043 12.1 0.8 0.057 11.7 0.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 SlyX PF04102.12 AAG05339.1 - 1.8 9.3 6.3 2.9 8.6 6.3 1.3 1 0 0 1 1 1 0 SlyX Peptidase_C39 PF03412.15 AAG05341.1 - 3.5e-21 75.4 0.0 6.8e-21 74.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase C39 family DUF3335 PF11814.8 AAG05341.1 - 0.0054 16.2 0.0 0.52 9.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Beta_helix_2 PF18835.1 AAG05342.1 - 0.012 15.4 3.5 0.049 13.4 3.5 2.1 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase LytR_cpsA_psr PF03816.14 AAG05342.1 - 0.17 12.0 4.3 0.5 10.5 1.1 2.3 1 1 1 2 2 2 0 Cell envelope-related transcriptional attenuator domain Tic110 PF16940.5 AAG05342.1 - 0.79 8.1 6.6 1.1 7.6 6.6 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter AAA_28 PF13521.6 AAG05345.1 - 8.8e-31 107.3 0.1 1e-30 107.1 0.1 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAG05345.1 - 9.8e-05 22.9 0.0 0.00015 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG05345.1 - 0.0019 18.6 0.4 0.0079 16.6 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 AAG05345.1 - 0.015 15.1 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 AAG05345.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAG05345.1 - 0.029 14.7 0.0 0.048 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain CobU PF02283.16 AAG05345.1 - 0.05 13.2 0.4 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_14 PF13173.6 AAG05345.1 - 0.052 13.6 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAG05345.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 AAG05345.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 dNK PF01712.19 AAG05345.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase NMN_transporter PF04973.12 AAG05346.1 - 1.2e-55 188.2 18.2 1.3e-55 188.0 18.2 1.0 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter BacA PF02673.18 AAG05347.1 - 3.9e-85 285.6 11.9 4.5e-85 285.4 11.9 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA TerC PF03741.16 AAG05347.1 - 0.24 11.0 6.7 4.3 7.0 6.5 2.3 1 1 0 1 1 1 0 Integral membrane protein TerC family DUF1294 PF06961.13 AAG05348.1 - 4.6e-24 84.4 1.7 6.9e-24 83.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) CSD PF00313.22 AAG05348.1 - 2.6e-09 36.8 0.0 4.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain S1-like PF14444.6 AAG05348.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 S1-like LysR_substrate PF03466.20 AAG05349.1 - 3.3e-40 137.7 8.0 5.2e-40 137.1 8.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05349.1 - 5.9e-18 64.6 0.2 1.5e-17 63.3 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Flavodoxin_2 PF02525.17 AAG05350.1 - 6.7e-47 159.8 0.0 7.5e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAG05350.1 - 1.6e-13 50.7 0.1 2.1e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DZR PF12773.7 AAG05351.1 - 0.042 13.9 3.4 0.061 13.4 3.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon CENP-W PF15510.6 AAG05351.1 - 0.13 12.5 0.4 0.24 11.6 0.4 1.4 1 0 0 1 1 1 0 CENP-W protein ABC_tran PF00005.27 AAG05352.1 - 1e-41 142.6 0.0 1.4e-20 74.2 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AAG05352.1 - 1e-22 79.9 1.6 4.4e-21 74.7 0.6 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAG05352.1 - 5.4e-17 62.6 5.8 0.00077 19.4 0.0 4.6 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAG05352.1 - 2.9e-06 26.9 0.1 0.079 12.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG05352.1 - 3.9e-06 27.3 0.0 0.0017 18.7 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_15 PF13175.6 AAG05352.1 - 5.1e-06 26.5 0.6 0.049 13.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 AAG05352.1 - 1.6e-05 24.0 0.4 0.0063 15.5 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 AAG05352.1 - 2.3e-05 24.2 0.1 0.056 13.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 AAG05352.1 - 2.6e-05 23.8 7.1 3.1 7.2 0.4 4.6 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG05352.1 - 3.6e-05 24.4 9.1 0.011 16.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 AAG05352.1 - 4.2e-05 23.5 0.2 0.048 13.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 AAG05352.1 - 4.3e-05 23.8 0.2 0.28 11.5 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 AAG05352.1 - 5.4e-05 23.5 0.0 0.22 11.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 AAG05352.1 - 5.6e-05 23.5 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 AAG05352.1 - 7.1e-05 22.8 0.2 0.039 13.9 0.0 2.6 3 0 0 3 3 2 1 RsgA GTPase AAA_14 PF13173.6 AAG05352.1 - 0.00011 22.2 0.0 0.47 10.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 AAG05352.1 - 0.00017 22.0 0.0 0.47 10.9 0.0 3.0 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAG05352.1 - 0.00056 20.0 0.0 0.52 10.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 AAG05352.1 - 0.00064 19.9 0.0 0.87 9.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 AAG05352.1 - 0.001 19.1 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 AAG05352.1 - 0.0011 19.5 0.0 1.6 9.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 AAG05352.1 - 0.014 15.0 0.1 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 AAG05352.1 - 0.021 14.8 0.1 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 AAG05352.1 - 0.023 14.4 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 AAG05352.1 - 0.028 14.3 0.2 1.7 8.5 0.0 2.5 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 AAG05352.1 - 0.03 13.8 0.1 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region BRE1 PF08647.11 AAG05352.1 - 0.031 14.3 3.8 0.059 13.4 3.8 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase AAA_30 PF13604.6 AAG05352.1 - 0.033 13.9 0.0 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAG05352.1 - 0.043 13.4 0.2 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 AAG05352.1 - 0.048 13.5 0.6 3.5 7.4 0.0 2.8 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 AAG05352.1 - 0.05 13.5 1.1 1.5 8.7 0.1 3.2 3 0 0 3 3 3 0 NTPase DUF87 PF01935.17 AAG05352.1 - 0.059 13.5 0.2 31 4.6 0.0 3.4 4 0 0 4 4 4 0 Helicase HerA, central domain NB-ARC PF00931.22 AAG05352.1 - 0.07 12.3 0.6 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_27 PF13514.6 AAG05352.1 - 0.094 12.3 0.1 22 4.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 AAG05352.1 - 0.1 12.0 0.1 5.7 6.3 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAG05352.1 - 0.12 12.1 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AAG05352.1 - 0.13 12.3 0.4 18 5.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 AAG05352.1 - 0.13 12.0 0.1 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 AAG05352.1 - 0.14 12.0 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 AAG05352.1 - 0.15 12.3 0.1 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3584 PF12128.8 AAG05352.1 - 0.69 7.3 6.7 0.34 8.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) CHMI PF02962.15 AAG05354.1 - 2.5e-16 60.1 0.0 2.7e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 5-carboxymethyl-2-hydroxymuconate isomerase CSTF_C PF14304.6 AAG05355.1 - 0.01 15.4 0.2 0.023 14.3 0.2 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal DUF1488 PF07369.11 AAG05356.1 - 0.12 12.4 2.4 0.17 11.9 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1488) Inhibitor_I78 PF11720.8 AAG05357.1 - 8.9e-17 60.9 0.1 1.3e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family DUF3558 PF12079.8 AAG05357.1 - 0.025 14.6 3.1 0.029 14.4 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) LPAM_1 PF08139.12 AAG05357.1 - 0.084 13.4 1.8 0.14 12.7 1.8 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site MLTD_N PF06474.12 AAG05357.1 - 0.15 12.2 1.9 0.34 11.1 1.9 1.6 1 0 0 1 1 1 0 MltD lipid attachment motif MLTD_N PF06474.12 AAG05358.1 - 0.25 11.5 2.4 0.55 10.4 2.4 1.6 1 0 0 1 1 1 0 MltD lipid attachment motif Branch_AA_trans PF05525.13 AAG05359.1 - 6.2e-157 522.9 30.9 7.1e-157 522.7 30.9 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein Sulfatase PF00884.23 AAG05360.1 - 7.4e-53 179.9 0.0 8.9e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase EptA_B_N PF08019.12 AAG05360.1 - 3.8e-52 176.2 3.6 3.8e-52 176.2 3.6 1.4 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB Peptidase_M16 PF00675.20 AAG05361.1 - 7.2e-29 100.7 0.0 1.3e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AAG05361.1 - 5.3e-14 52.7 0.0 3.3e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Porin_4 PF13609.6 AAG05362.1 - 2.3e-24 86.7 20.5 2.9e-24 86.4 20.5 1.1 1 0 0 1 1 1 1 Gram-negative porin FIST PF08495.10 AAG05363.1 - 1.9e-34 119.2 1.2 4.3e-34 118.0 1.2 1.6 1 0 0 1 1 1 1 FIST N domain FIST_C PF10442.9 AAG05363.1 - 1.3e-14 54.3 1.0 9.8e-12 45.0 0.1 2.5 2 0 0 2 2 2 2 FIST C domain PAS_4 PF08448.10 AAG05364.1 - 9e-36 122.5 5.7 4.4e-26 91.3 0.2 4.8 3 2 0 3 3 3 3 PAS fold PAS_7 PF12860.7 AAG05364.1 - 2.6e-28 98.5 4.0 6.2e-14 52.2 0.1 5.8 3 3 1 4 4 4 2 PAS fold HATPase_c PF02518.26 AAG05364.1 - 9.4e-21 74.4 0.0 2.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG05364.1 - 1.3e-11 44.3 2.8 1.3e-10 41.2 0.3 4.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAG05364.1 - 5.7e-11 42.6 0.0 1.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 AAG05364.1 - 2.3e-07 30.6 0.1 0.015 15.3 0.0 3.4 2 0 0 2 2 2 2 PAS domain PAS_10 PF13596.6 AAG05364.1 - 2.7e-05 24.7 0.0 0.001 19.6 0.0 3.3 4 0 0 4 4 4 1 PAS domain PAS PF00989.25 AAG05364.1 - 3e-05 24.0 2.9 1.8 8.6 0.0 4.5 5 1 0 5 5 5 2 PAS fold PAS_9 PF13426.7 AAG05364.1 - 0.00014 22.1 0.0 0.035 14.3 0.0 3.6 3 0 0 3 3 3 1 PAS domain HATPase_c_2 PF13581.6 AAG05364.1 - 0.1 12.6 0.0 0.42 10.6 0.0 2.0 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Striatin PF08232.12 AAG05364.1 - 0.12 13.0 0.3 0.12 13.0 0.3 2.5 2 0 0 2 2 2 0 Striatin family CAP59_mtransfer PF11735.8 AAG05364.1 - 0.24 11.0 1.6 1.3 8.7 1.7 1.9 2 0 0 2 2 2 0 Cryptococcal mannosyltransferase 1 Filament PF00038.21 AAG05364.1 - 0.28 10.7 11.2 0.027 14.1 3.4 2.3 2 0 0 2 2 2 0 Intermediate filament protein Osmo_CC PF08946.10 AAG05364.1 - 0.53 10.6 5.4 0.41 10.9 0.6 2.9 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Exonuc_VII_L PF02601.15 AAG05364.1 - 3.4 7.1 11.0 3.8 7.0 3.6 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit HAUS-augmin3 PF14932.6 AAG05364.1 - 9.6 5.7 15.3 0.22 11.0 4.5 2.6 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 EamA PF00892.20 AAG05365.1 - 5.2e-24 85.0 32.0 5.6e-14 52.5 13.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family Response_reg PF00072.24 AAG05366.1 - 2.8e-29 101.5 0.1 4.7e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG05366.1 - 5.5e-21 73.9 1.7 8.8e-21 73.2 1.7 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG05366.1 - 6.9e-05 22.4 0.3 0.00013 21.6 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 TadZ_N PF16968.5 AAG05366.1 - 0.0088 15.7 0.1 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Pilus assembly protein TadZ N-terminal Sigma70_r4 PF04545.16 AAG05366.1 - 0.017 14.6 0.4 0.035 13.6 0.4 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.6 AAG05366.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_7 PF02796.15 AAG05366.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_10 PF04967.12 AAG05366.1 - 0.36 10.6 2.2 0.36 10.6 0.2 2.1 2 0 0 2 2 2 0 HTH DNA binding domain HisKA_3 PF07730.13 AAG05367.1 - 1e-08 35.6 0.0 3e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 AAG05367.1 - 2.1e-07 31.5 0.0 4.1e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAG05367.1 - 0.00016 21.6 0.0 0.00048 20.1 0.0 1.7 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain Response_reg PF00072.24 AAG05368.1 - 4.2e-27 94.5 0.0 6.6e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG05368.1 - 9.1e-15 54.0 0.2 1.3e-14 53.4 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 AAG05368.1 - 4.4e-06 26.4 0.0 9.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAG05368.1 - 1e-05 25.1 0.2 2.4e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG05368.1 - 2.9e-05 23.7 0.1 0.00012 21.8 0.1 2.1 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AAG05368.1 - 0.00052 19.5 0.7 0.0014 18.1 0.7 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_1 PF00126.27 AAG05368.1 - 0.00055 19.8 2.6 0.00055 19.8 1.1 1.8 2 0 0 2 2 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AAG05368.1 - 0.001 19.2 1.9 0.003 17.6 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_10 PF04967.12 AAG05368.1 - 0.0012 18.6 0.4 0.0062 16.3 0.1 2.4 2 0 0 2 2 2 1 HTH DNA binding domain HTH_20 PF12840.7 AAG05368.1 - 0.0012 18.8 0.1 0.0042 17.1 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAG05368.1 - 0.0017 17.7 0.2 0.0049 16.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 AAG05368.1 - 0.002 18.0 0.1 0.0059 16.5 0.1 1.8 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AAG05368.1 - 0.0021 17.6 0.1 0.0052 16.3 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 AAG05368.1 - 0.0029 18.0 0.0 0.006 17.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain LacI PF00356.21 AAG05368.1 - 0.0055 16.5 0.4 0.011 15.5 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family DUF746 PF05344.11 AAG05368.1 - 0.0079 16.0 0.1 0.16 11.9 0.1 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF746) Sigma70_ECF PF07638.11 AAG05368.1 - 0.01 15.7 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 ECF sigma factor MarR_2 PF12802.7 AAG05368.1 - 0.01 15.7 2.9 0.033 14.1 0.6 2.9 2 1 1 3 3 3 0 MarR family HTH_5 PF01022.20 AAG05368.1 - 0.016 15.0 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_3 PF01381.22 AAG05368.1 - 0.09 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix Phage_terminase PF10668.9 AAG05368.1 - 0.093 12.8 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 1 0 Phage terminase small subunit Trp_repressor PF01371.19 AAG05368.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein Flu_NP PF00506.18 AAG05368.1 - 0.19 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein TnsD PF15978.5 AAG05368.1 - 0.25 10.3 0.0 0.35 9.8 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Pentapeptide PF00805.22 AAG05369.1 - 2.4e-41 138.9 19.9 3e-11 42.7 2.2 4.5 3 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AAG05369.1 - 2.4e-17 62.9 0.0 1e-07 32.0 0.0 3.0 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AAG05369.1 - 3e-14 52.9 0.0 0.023 14.8 0.0 5.1 3 2 1 4 4 4 4 Pentapeptide repeats (9 copies) DNA_ligase_OB PF03120.16 AAG05369.1 - 0.041 13.8 0.0 15 5.6 0.0 3.4 2 2 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain PQQ PF01011.21 AAG05370.1 - 1.8e-32 109.7 16.1 1.3e-10 40.6 0.0 9.0 10 0 0 10 10 10 7 PQQ enzyme repeat PQQ_2 PF13360.6 AAG05370.1 - 3.4e-26 92.3 5.5 1.2e-16 61.1 0.5 3.2 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 AAG05370.1 - 1.3e-20 73.3 24.0 4.1e-07 30.3 0.2 8.1 8 1 0 8 8 8 5 PQQ-like domain Cytochrome_CBB3 PF13442.6 AAG05371.1 - 6.4e-14 52.0 0.0 9.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG05371.1 - 4.3e-06 27.8 0.0 9.6e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome c Aldedh PF00171.22 AAG05372.1 - 1.6e-163 544.5 0.0 1.8e-163 544.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PqqA PF08042.11 AAG05373.1 - 3.6e-11 42.6 0.0 3.9e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 PqqA family Lactamase_B_2 PF12706.7 AAG05374.1 - 2.8e-48 164.1 0.0 3.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TENA_THI-4 PF03070.16 AAG05375.1 - 1.3e-70 237.5 0.3 1.5e-70 237.3 0.3 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PqqD PF05402.12 AAG05376.1 - 1e-15 57.7 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) Radical_SAM PF04055.21 AAG05377.1 - 1e-22 81.3 0.0 1.5e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 AAG05377.1 - 5.7e-08 33.2 0.1 1.2e-07 32.1 0.1 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 AAG05377.1 - 1.6e-06 28.5 0.0 2.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAG05377.1 - 3.8e-06 27.0 0.0 7.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain AP_endonuc_2 PF01261.24 AAG05377.1 - 0.0015 18.0 0.4 0.01 15.3 0.4 2.0 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Peptidase_S9 PF00326.21 AAG05378.1 - 8.2e-37 126.7 0.0 1.1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAG05378.1 - 1.1e-09 38.0 0.0 0.00015 21.1 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 AAG05378.1 - 1.2e-07 31.5 0.0 2.9e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 AAG05378.1 - 4e-05 23.6 2.4 0.00014 21.8 1.1 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 AAG05378.1 - 0.0022 17.5 0.2 0.25 10.8 0.1 2.6 2 0 0 2 2 2 1 Esterase PHB depolymerase COesterase PF00135.28 AAG05378.1 - 0.021 13.7 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_1 PF00561.20 AAG05378.1 - 0.097 12.3 0.0 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 AAG05378.1 - 0.28 9.8 0.2 10 4.7 0.1 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Fe-ADH PF00465.19 AAG05379.1 - 4.8e-115 384.2 0.0 5.5e-115 384.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AAG05379.1 - 9.6e-17 61.5 0.2 5.6e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase HATPase_c PF02518.26 AAG05380.1 - 1.7e-19 70.4 0.0 2.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAG05380.1 - 6.4e-12 45.6 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAG05380.1 - 1.2e-05 25.2 2.6 1.2e-05 25.2 2.6 2.9 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAG05380.1 - 1.5e-05 25.2 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAG05380.1 - 3.3e-05 23.8 0.2 0.00023 21.1 0.1 2.6 2 0 0 2 2 2 1 PAS domain HATPase_c_2 PF13581.6 AAG05380.1 - 0.0071 16.3 0.2 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain NPFF PF15085.6 AAG05380.1 - 0.0082 16.5 0.3 0.0082 16.5 0.3 3.0 2 1 1 3 3 3 1 Neuropeptide FF GAS PF13851.6 AAG05380.1 - 0.022 14.1 5.8 0.92 8.8 2.4 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PAS PF00989.25 AAG05380.1 - 0.075 13.0 0.8 0.56 10.2 0.0 2.7 1 1 1 2 2 2 0 PAS fold Herpes_UL6 PF01763.16 AAG05380.1 - 0.11 11.0 0.3 0.15 10.5 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like OmpH PF03938.14 AAG05380.1 - 0.11 12.8 2.0 0.22 11.8 2.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rho_Binding PF08912.11 AAG05380.1 - 0.13 13.1 2.4 0.17 12.7 1.3 1.8 1 1 0 1 1 1 0 Rho Binding DCB PF16213.5 AAG05380.1 - 0.17 11.5 0.4 0.3 10.7 0.4 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 TMCO5 PF14992.6 AAG05380.1 - 0.2 11.2 3.2 0.29 10.7 3.2 1.2 1 0 0 1 1 1 0 TMCO5 family Mce4_CUP1 PF11887.8 AAG05380.1 - 0.22 11.0 0.9 0.38 10.2 0.9 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative MctB PF11382.8 AAG05380.1 - 0.44 10.2 4.1 0.32 10.6 2.1 1.7 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB PKcGMP_CC PF16808.5 AAG05380.1 - 2.1 8.3 5.6 5.4 7.0 5.6 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4355 PF14265.6 AAG05380.1 - 2.7 8.2 7.3 1.3 9.3 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF4140 PF13600.6 AAG05380.1 - 4 7.9 7.7 8.8 6.8 4.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MFS_1 PF07690.16 AAG05381.1 - 2.7e-22 79.2 70.0 1.3e-10 40.7 32.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAG05381.1 - 0.00097 18.1 18.4 0.11 11.3 0.6 2.2 2 0 0 2 2 2 2 MFS_1 like family Glycolipid_bind PF06475.11 AAG05382.1 - 4.6e-55 185.9 0.0 5.2e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Putative glycolipid-binding YjbR PF04237.13 AAG05383.1 - 1.4e-13 51.2 0.0 1.7e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 YjbR Rotamase PF00639.21 AAG05384.1 - 2.5e-19 70.0 0.0 3.4e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AAG05384.1 - 1.1e-16 61.4 0.0 1.5e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAG05384.1 - 4.9e-06 27.4 0.0 6.1e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF3591 PF12157.8 AAG05384.1 - 0.084 11.5 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) AMP-binding PF00501.28 AAG05385.1 - 2.1e-43 148.5 0.0 2.7e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 AAG05385.1 - 1e-11 44.5 0.1 1.9e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 AAG05385.1 - 7e-05 23.7 0.2 0.00023 22.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain EpuA PF11772.8 AAG05385.1 - 0.082 12.6 0.2 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta LysR_substrate PF03466.20 AAG05386.1 - 3.5e-42 144.1 5.1 6e-42 143.4 5.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05386.1 - 9.2e-22 76.8 1.2 9.2e-22 76.8 1.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG05386.1 - 0.075 12.9 0.8 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 MarR family PBP_like PF12727.7 AAG05386.1 - 0.087 11.9 0.0 0.62 9.1 0.0 2.0 2 0 0 2 2 2 0 PBP superfamily domain HTH_AsnC-type PF13404.6 AAG05386.1 - 0.11 12.3 0.9 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain CoA_trans PF01144.23 AAG05387.1 - 5.7e-78 261.2 0.2 6.3e-78 261.1 0.2 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 AAG05388.1 - 1.7e-41 142.0 0.4 2e-41 141.8 0.4 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 AAG05388.1 - 6.5e-06 26.2 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Thiolase_N PF00108.23 AAG05389.1 - 1.9e-106 355.2 0.6 2.5e-106 354.8 0.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG05389.1 - 6.7e-52 174.3 0.9 4.3e-51 171.7 0.5 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG05389.1 - 9.2e-06 25.4 0.6 9.2e-06 25.4 0.6 2.6 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AAG05389.1 - 0.13 12.1 3.5 1.3 9.0 0.2 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DSBA PF01323.20 AAG05389.1 - 0.21 11.3 2.3 0.4 10.4 0.1 2.4 3 0 0 3 3 3 0 DSBA-like thioredoxin domain SCFA_trans PF02667.14 AAG05390.1 - 4.9e-83 279.6 20.7 6e-83 279.3 20.7 1.0 1 0 0 1 1 1 1 Short chain fatty acid transporter DcuC PF03606.15 AAG05390.1 - 3.1e-05 22.6 2.1 3.1e-05 22.6 2.1 2.5 3 0 0 3 3 3 2 C4-dicarboxylate anaerobic carrier adh_short PF00106.25 AAG05391.1 - 1.4e-54 184.5 0.0 1.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG05391.1 - 7.6e-53 179.5 0.1 1.1e-52 178.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG05391.1 - 2.1e-09 37.6 0.4 3.2e-09 37.0 0.4 1.3 1 0 0 1 1 1 1 KR domain Flagellar_rod PF05149.12 AAG05391.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein HTH_15 PF12324.8 AAG05392.1 - 0.072 13.1 0.7 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase DUF5056 PF16479.5 AAG05392.1 - 0.62 10.3 2.2 5.4 7.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) Myco_arth_vir_N PF09610.10 AAG05392.1 - 7.3 6.8 9.7 0.71 10.0 0.2 3.6 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Sigma54_activat PF00158.26 AAG05393.1 - 2.6e-63 212.7 0.0 5.4e-63 211.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG05393.1 - 3.4e-21 75.8 0.0 9.3e-21 74.4 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG05393.1 - 1.3e-12 47.3 0.5 4.4e-12 45.6 0.5 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family PAS_4 PF08448.10 AAG05393.1 - 2.9e-08 33.9 0.0 5e-07 30.0 0.0 2.7 1 1 0 1 1 1 1 PAS fold AAA_5 PF07728.14 AAG05393.1 - 6.4e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG05393.1 - 4.7e-06 26.1 1.2 4.3e-05 23.0 1.2 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI PAS_8 PF13188.7 AAG05393.1 - 9.6e-06 25.5 0.3 6.4e-05 22.9 0.0 2.5 3 0 0 3 3 3 1 PAS domain AAA PF00004.29 AAG05393.1 - 0.00023 21.6 0.0 0.00097 19.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PAS PF00989.25 AAG05393.1 - 0.00045 20.2 0.0 0.0047 16.9 0.0 2.3 1 1 0 1 1 1 1 PAS fold PAS_7 PF12860.7 AAG05393.1 - 0.0019 18.4 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG05393.1 - 0.011 15.9 0.0 0.039 14.2 0.0 2.0 1 1 0 1 1 1 0 PAS domain IstB_IS21 PF01695.17 AAG05393.1 - 0.025 14.3 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein HTH_29 PF13551.6 AAG05393.1 - 0.039 14.0 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix AAA_2 PF07724.14 AAG05393.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_30 PF13556.6 AAG05393.1 - 0.07 12.9 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain dCache_1 PF02743.18 AAG05393.1 - 0.087 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Cache domain HTH_17 PF12728.7 AAG05393.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SLATT_1 PF18181.1 AAG05393.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 HTH_50 PF18024.1 AAG05393.1 - 0.11 12.1 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_7 PF12775.7 AAG05393.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_7 PF02796.15 AAG05393.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase AAA_19 PF13245.6 AAG05393.1 - 0.17 12.2 0.1 29 5.0 0.1 2.4 1 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 AAG05394.1 - 6.1e-61 206.3 70.8 5.5e-49 167.0 43.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG05394.1 - 9.8e-19 67.5 11.5 9.8e-19 67.5 11.5 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAG05394.1 - 5.9e-08 32.4 7.8 5.9e-08 32.4 7.8 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 AAG05394.1 - 1.1e-07 30.8 23.4 0.00027 19.6 6.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_5 PF05631.14 AAG05394.1 - 0.00054 19.0 0.3 0.00054 19.0 0.3 1.6 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 AAG05394.1 - 0.078 11.8 27.2 0.025 13.5 5.9 2.4 2 0 0 2 2 2 0 MFS_1 like family GST_N_3 PF13417.6 AAG05395.1 - 9.7e-18 64.4 0.1 1.5e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAG05395.1 - 1.5e-15 57.3 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG05395.1 - 1.1e-14 54.4 0.0 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAG05395.1 - 8.6e-07 28.9 0.4 1.8e-06 27.9 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAG05395.1 - 4e-05 23.7 0.0 7.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG05395.1 - 0.0078 16.4 0.0 0.022 15.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AAG05395.1 - 0.024 15.0 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 AAG05395.1 - 0.16 12.8 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain HTH_28 PF13518.6 AAG05395.1 - 1.4 9.1 4.3 7.8 6.7 0.2 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain FAA_hydrolase PF01557.18 AAG05396.1 - 4.5e-58 196.5 0.0 5.8e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 AAG05396.1 - 5.5e-23 81.2 0.0 8.8e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 AAG05397.1 - 5.1e-213 707.5 0.0 5.7e-213 707.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase IclR PF01614.18 AAG05398.1 - 1.4e-16 60.5 0.0 2.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AAG05398.1 - 1e-13 50.8 0.2 2.8e-13 49.4 0.2 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AAG05398.1 - 5.6e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAG05398.1 - 0.00012 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AAG05398.1 - 0.0016 18.3 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 AAG05398.1 - 0.035 13.9 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 AAG05398.1 - 0.042 13.8 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_45 PF14947.6 AAG05398.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix HMGL-like PF00682.19 AAG05399.1 - 3.5e-53 180.8 0.0 4e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 HMGL-like CPSase_L_D2 PF02786.17 AAG05400.1 - 3.2e-79 265.3 0.0 4.7e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAG05400.1 - 1.9e-42 144.2 0.2 1.9e-41 141.0 0.1 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAG05400.1 - 1.8e-37 127.7 0.0 3.5e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AAG05400.1 - 1.3e-18 66.5 0.1 3.2e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 AAG05400.1 - 9.5e-13 48.1 0.0 2e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAG05400.1 - 1.7e-09 37.5 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 AAG05400.1 - 2.4e-09 36.9 0.0 0.002 17.9 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AAG05400.1 - 2.1e-05 25.2 0.1 0.07 13.8 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 AAG05400.1 - 0.00025 21.1 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 AAG05400.1 - 0.0006 19.1 0.0 0.66 9.2 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GARS_A PF01071.19 AAG05400.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 AAG05400.1 - 0.012 14.9 0.0 0.75 9.0 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 AAG05400.1 - 0.037 13.6 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain LAL_C2 PF18603.1 AAG05400.1 - 0.04 14.1 1.1 0.28 11.4 0.0 3.1 3 1 1 4 4 3 0 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 AAG05400.1 - 0.062 13.0 0.6 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ECH_1 PF00378.20 AAG05401.1 - 1.8e-53 181.4 0.0 2.2e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG05401.1 - 4.8e-30 105.2 0.0 1.7e-26 93.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 AAG05402.1 - 5e-157 523.5 0.1 6.3e-157 523.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAG05402.1 - 9.7e-05 22.0 2.3 0.024 14.1 0.1 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.24 AAG05403.1 - 2.6e-41 141.3 0.4 4.1e-41 140.7 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG05403.1 - 5.7e-38 130.1 0.1 1.2e-37 129.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05403.1 - 2.9e-28 97.9 0.0 6.9e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG05403.1 - 2.4e-14 53.8 0.1 4e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG05403.1 - 0.015 15.0 0.1 0.062 13.0 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 AAG05403.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Staphylococcal AgrD protein MerR_1 PF13411.6 AAG05404.1 - 2.2e-16 59.7 0.2 4.5e-16 58.7 0.2 1.5 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AAG05404.1 - 3.5e-15 56.3 2.2 7.2e-15 55.3 2.2 1.5 1 0 0 1 1 1 1 MerR, DNA binding MerR PF00376.23 AAG05404.1 - 6.5e-11 41.8 0.6 1e-10 41.2 0.6 1.3 1 0 0 1 1 1 1 MerR family regulatory protein Lge1 PF11488.8 AAG05404.1 - 0.018 15.2 1.0 0.028 14.6 1.0 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 SdiA-regulated PF06977.11 AAG05405.1 - 7.9e-96 320.1 0.0 9.3e-96 319.8 0.0 1.0 1 0 0 1 1 1 1 SdiA-regulated Phytase-like PF13449.6 AAG05405.1 - 1.7e-12 47.9 0.4 2.4e-07 31.0 0.1 2.6 2 1 0 2 2 2 2 Esterase-like activity of phytase Nkap_C PF06047.11 AAG05405.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain ACR_tran PF00873.19 AAG05406.1 - 0 1200.3 6.0 0 1200.1 6.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG05406.1 - 5.3e-13 48.6 33.2 1.3e-10 40.7 11.4 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAG05406.1 - 0.00014 21.4 26.3 0.0014 18.1 2.1 2.5 2 0 0 2 2 2 2 Protein export membrane protein DUF4321 PF14209.6 AAG05406.1 - 0.22 11.4 9.0 0.22 11.4 3.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4321) Patched PF02460.18 AAG05406.1 - 8.5 4.3 12.0 12 3.8 12.0 1.2 1 0 0 1 1 1 0 Patched family HlyD PF00529.20 AAG05407.1 - 3.6e-12 46.0 0.5 4.7e-12 45.6 0.5 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_D23 PF16576.5 AAG05407.1 - 4.1e-11 42.5 0.2 1.6e-10 40.6 0.2 1.9 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG05407.1 - 5e-10 39.1 3.3 2.2e-08 33.8 0.0 3.6 4 0 0 4 4 4 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAG05407.1 - 6.7e-08 33.2 2.7 0.0017 19.1 0.0 3.6 4 1 0 4 4 4 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AAG05407.1 - 0.01 15.7 0.0 0.13 12.1 0.0 2.6 3 0 0 3 3 3 1 Biotin-requiring enzyme DUF1204 PF06721.11 AAG05407.1 - 0.054 13.0 1.1 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) HD_2 PF12917.7 AAG05407.1 - 0.074 12.8 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme OEP PF02321.18 AAG05407.1 - 0.081 12.7 9.8 0.14 12.0 9.8 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein TetR_N PF00440.23 AAG05408.1 - 4.6e-14 51.9 0.5 9e-14 51.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_2 PF08361.11 AAG05408.1 - 7.8e-09 35.7 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 MAATS-type transcriptional repressor, C-terminal region TetR_C_11 PF16859.5 AAG05408.1 - 0.0035 17.6 2.6 0.0052 17.1 1.3 2.0 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAG05408.1 - 0.0071 16.6 0.4 0.012 15.8 0.4 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_17 PF17922.1 AAG05408.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3203 PF11462.8 AAG05409.1 - 5.5e-35 119.4 0.8 6.1e-35 119.3 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3203) YabP PF07873.11 AAG05409.1 - 0.12 12.1 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 YabP family UDPG_MGDP_dh_N PF03721.14 AAG05410.1 - 6.1e-61 205.3 0.0 8.4e-61 204.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAG05410.1 - 1.1e-37 128.1 0.1 2.5e-37 126.9 0.0 1.6 2 0 0 2 2 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAG05410.1 - 1.1e-30 106.1 0.0 7.3e-29 100.3 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 AAG05410.1 - 3.4e-06 26.8 0.0 0.00019 21.1 0.0 2.3 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 AAG05410.1 - 0.00015 22.2 0.0 0.00037 21.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAG05410.1 - 0.00031 20.1 0.0 0.0006 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 AAG05410.1 - 0.00034 21.1 0.1 0.046 14.3 0.0 3.5 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 AAG05410.1 - 0.0005 20.1 0.0 0.0021 18.1 0.0 2.0 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 AAG05410.1 - 0.00063 19.7 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAG05410.1 - 0.0013 18.9 0.0 0.0051 17.0 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 AAG05410.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 AAG05410.1 - 0.011 16.0 0.2 0.055 13.7 0.2 2.4 1 1 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 AAG05410.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AAG05410.1 - 0.029 14.6 0.0 0.091 13.0 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAG05410.1 - 0.036 13.7 6.6 0.05 13.2 0.1 2.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase NTP_transferase PF00483.23 AAG05411.1 - 3.4e-31 108.7 0.0 4.3e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAG05411.1 - 7e-07 29.7 0.0 1.5e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Glyoxalase PF00903.25 AAG05412.1 - 3.4e-09 37.0 0.0 4.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG05412.1 - 0.00011 23.0 0.0 0.00015 22.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAG05412.1 - 0.0068 16.7 0.0 0.0091 16.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pyr_redox_2 PF07992.14 AAG05413.1 - 1.6e-68 231.1 0.0 2.2e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAG05413.1 - 1.2e-35 122.0 0.3 2.1e-35 121.3 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAG05413.1 - 4.7e-20 71.9 8.0 1.7e-18 66.9 0.0 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG05413.1 - 3.8e-16 59.2 0.0 1.4e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AAG05413.1 - 1.9e-06 27.2 0.0 0.00016 21.0 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 AAG05413.1 - 4.6e-06 26.1 0.5 0.017 14.4 0.6 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AAG05413.1 - 7.9e-06 24.8 0.3 0.11 11.1 0.0 3.4 4 0 0 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.7 AAG05413.1 - 2.8e-05 23.7 0.3 2.8e-05 23.7 0.3 1.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG05413.1 - 0.0016 17.6 2.6 0.12 11.4 2.2 2.4 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 AAG05413.1 - 0.0023 17.1 6.1 0.0086 15.2 2.6 3.0 2 2 1 3 3 3 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 AAG05413.1 - 0.0047 16.3 0.0 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase XdhC_C PF13478.6 AAG05413.1 - 0.012 16.2 0.0 6.8 7.2 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 AAG05413.1 - 0.013 15.9 0.0 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 AAG05413.1 - 0.013 14.9 0.5 2.7 7.3 0.4 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAG05413.1 - 0.016 15.1 0.3 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AAG05413.1 - 0.1 12.8 7.1 0.095 12.9 1.6 3.3 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AAG05413.1 - 0.15 11.1 0.2 0.96 8.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAG05413.1 - 0.27 11.2 3.0 0.32 11.0 0.0 2.6 3 0 0 3 3 2 0 FAD-NAD(P)-binding DAO PF01266.24 AAG05413.1 - 4.7 6.7 12.9 3.3 7.2 0.1 3.4 1 1 2 4 4 4 0 FAD dependent oxidoreductase SBF_like PF13593.6 AAG05414.1 - 4.5e-103 344.8 23.8 5.1e-103 344.7 23.8 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 AAG05414.1 - 3.3e-16 59.5 8.5 3.3e-16 59.5 8.5 2.5 1 1 1 2 2 2 1 Sodium Bile acid symporter family ACT_5 PF13710.6 AAG05415.1 - 0.058 13.2 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 ACT domain AsnC_trans_reg PF01037.21 AAG05416.1 - 3.8e-21 74.8 0.0 5.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAG05416.1 - 4.7e-19 67.7 0.5 7.1e-19 67.1 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAG05416.1 - 1.2e-16 60.2 0.5 3e-16 59.0 0.5 1.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 AAG05416.1 - 1.9e-06 27.7 0.5 4.3e-06 26.6 0.5 1.6 2 0 0 2 2 1 1 HTH domain HTH_Crp_2 PF13545.6 AAG05416.1 - 5.3e-06 26.3 0.3 9.8e-06 25.5 0.3 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAG05416.1 - 3.9e-05 23.4 0.1 6.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAG05416.1 - 4.6e-05 23.2 1.2 0.00047 20.0 0.5 2.2 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 AAG05416.1 - 0.00039 20.2 0.1 0.00082 19.1 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AAG05416.1 - 0.00046 20.2 0.0 0.00075 19.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AAG05416.1 - 0.00069 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.12 AAG05416.1 - 0.00088 18.9 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_1 PF00126.27 AAG05416.1 - 0.0012 18.7 0.1 0.0021 18.0 0.1 1.5 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_DeoR PF08220.12 AAG05416.1 - 0.0012 18.5 0.1 0.0024 17.6 0.1 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 AAG05416.1 - 0.0019 18.0 0.1 0.003 17.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 AAG05416.1 - 0.0019 18.5 0.1 0.0038 17.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_23 PF13384.6 AAG05416.1 - 0.0056 16.4 0.3 0.0098 15.7 0.3 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_39 PF14090.6 AAG05416.1 - 0.01 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FaeA PF04703.12 AAG05416.1 - 0.013 15.9 0.0 0.031 14.6 0.0 1.6 2 0 0 2 2 1 0 FaeA-like protein HTH_Mga PF08280.11 AAG05416.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Fe_dep_repress PF01325.19 AAG05416.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Replic_Relax PF13814.6 AAG05416.1 - 0.031 14.3 0.1 0.042 13.9 0.1 1.3 1 0 0 1 1 1 0 Replication-relaxation LexA_DNA_bind PF01726.16 AAG05416.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 LexA DNA binding domain GntR PF00392.21 AAG05416.1 - 0.074 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_29 PF13551.6 AAG05416.1 - 0.076 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 AAG05416.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF603 PF04645.12 AAG05416.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Phage_rep_O PF04492.13 AAG05416.1 - 0.15 12.7 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication protein O HTH_38 PF13936.6 AAG05416.1 - 0.16 11.7 1.6 0.89 9.4 0.5 2.5 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_43 PF09904.9 AAG05417.1 - 8.8e-40 134.6 0.0 9.8e-40 134.4 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix HTH_20 PF12840.7 AAG05417.1 - 0.0033 17.4 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AAG05417.1 - 0.004 17.0 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 AAG05417.1 - 0.0042 16.8 0.1 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 AAG05417.1 - 0.053 13.6 0.1 0.095 12.7 0.0 1.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_IclR PF09339.10 AAG05417.1 - 0.057 13.2 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR_2 PF12802.7 AAG05417.1 - 0.075 12.9 0.4 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 MarR family HTH_9 PF08221.11 AAG05417.1 - 0.19 11.8 0.0 0.31 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DNA_RNApol_7kD PF03604.13 AAG05418.1 - 0.023 14.4 4.7 0.18 11.5 1.4 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 AAG05418.1 - 0.056 13.5 1.3 0.16 12.0 0.8 1.9 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 AAG05418.1 - 0.075 13.2 0.7 0.1 12.8 0.7 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 AAG05418.1 - 0.52 9.8 3.3 0.5 9.8 1.4 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DUF1127 PF06568.11 AAG05419.1 - 2.6e-07 30.2 8.1 2.6e-07 30.2 8.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1127) Aminotran_1_2 PF00155.21 AAG05420.1 - 1e-36 126.9 0.0 1.2e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAG05420.1 - 1.2e-14 53.7 0.1 3.8e-14 52.1 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AAG05420.1 - 0.00017 21.2 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Aminotran_MocR PF12897.7 AAG05420.1 - 0.21 10.3 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase FAD_binding_9 PF08021.11 AAG05421.1 - 7e-40 136.0 0.0 1.1e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 AAG05421.1 - 6.3e-38 129.9 0.5 1.3e-37 128.9 0.5 1.5 1 0 0 1 1 1 1 Siderophore-interacting protein Methyltransf_25 PF13649.6 AAG05422.1 - 6e-13 49.3 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG05422.1 - 6.7e-10 39.5 0.0 9.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG05422.1 - 2.1e-09 38.0 0.0 3.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG05422.1 - 4.5e-07 29.8 0.0 5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG05422.1 - 1.9e-05 24.5 0.0 4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAG05422.1 - 4e-05 23.0 0.0 4.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain FmrO PF07091.11 AAG05422.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.19 AAG05422.1 - 0.007 16.1 0.0 0.0099 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 AAG05422.1 - 0.0074 15.6 0.0 0.0092 15.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 AAG05422.1 - 0.0075 15.8 0.0 0.0087 15.7 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 AAG05422.1 - 0.013 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TPMT PF05724.11 AAG05422.1 - 0.018 14.7 0.1 0.053 13.2 0.1 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 AAG05422.1 - 0.063 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 AAG05422.1 - 0.068 12.7 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_10 PF05971.12 AAG05422.1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase TPP_enzyme_N PF02776.18 AAG05423.1 - 6e-57 192.0 1.0 1e-54 184.7 0.1 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAG05423.1 - 1.7e-43 148.0 0.1 3.7e-42 143.7 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG05423.1 - 7.5e-30 103.4 0.0 1.4e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Methyltransf_12 PF08242.12 AAG05424.1 - 7.5e-05 23.4 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG05424.1 - 0.00012 22.6 0.1 0.00018 22.1 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG05424.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 AAG05424.1 - 0.14 11.2 0.0 1.7 7.6 0.0 1.9 1 1 1 2 2 2 0 DREV methyltransferase Methyltransf_31 PF13847.6 AAG05424.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AzlD PF05437.12 AAG05426.1 - 7.8e-23 80.5 4.0 8.6e-23 80.4 4.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein (AzlD) AzlC PF03591.14 AAG05427.1 - 3.7e-36 124.6 7.3 3.7e-36 124.6 7.3 1.9 2 0 0 2 2 2 1 AzlC protein Gln-synt_C PF00120.24 AAG05428.1 - 4.2e-107 358.1 0.0 4.8e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 AAG05428.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 AAG05428.1 - 0.00096 18.8 0.0 0.026 14.2 0.0 2.5 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF1192 PF06698.11 AAG05428.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AA_permease PF00324.21 AAG05429.1 - 3.1e-38 131.6 37.9 3.9e-38 131.3 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG05429.1 - 4e-30 105.0 40.7 4.9e-30 104.7 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease SDF PF00375.18 AAG05430.1 - 2.1e-62 211.4 37.0 2.6e-62 211.1 37.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family PseudoU_synth_2 PF00849.22 AAG05431.1 - 6.1e-22 78.4 0.0 7.8e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3857 PF12969.7 AAG05432.1 - 2.3e-26 92.9 0.0 3.9e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3857) Transglut_core PF01841.19 AAG05432.1 - 5.6e-07 30.0 0.1 1.2e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AAG05432.1 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like domain YidD PF01809.18 AAG05433.1 - 1.7e-31 107.9 0.6 2.4e-31 107.4 0.6 1.2 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor AraC_N PF06719.13 AAG05435.1 - 6.3e-51 171.9 0.1 1.2e-50 171.0 0.1 1.5 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 AAG05435.1 - 5.3e-20 71.5 0.7 1.2e-19 70.3 0.3 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05435.1 - 6e-13 48.5 0.1 8.7e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_24 PF13412.6 AAG05435.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding BsuBI_PstI_RE_N PF17728.1 AAG05435.1 - 0.17 11.8 0.0 0.68 9.8 0.0 1.8 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease HTH domain ABM PF03992.16 AAG05436.1 - 2.4e-13 50.0 0.2 5.7e-13 48.8 0.1 1.6 1 1 1 2 2 2 1 Antibiotic biosynthesis monooxygenase PhoD PF09423.10 AAG05437.1 - 1.1e-05 24.6 0.5 0.00068 18.8 0.5 2.6 1 1 0 1 1 1 1 PhoD-like phosphatase Glyco_trans_2_3 PF13632.6 AAG05437.1 - 0.046 13.6 0.5 0.046 13.6 0.5 2.1 3 0 0 3 3 3 0 Glycosyl transferase family group 2 Sigma70_r2 PF04542.14 AAG05438.1 - 1.7e-13 50.1 0.1 3.8e-13 49.0 0.1 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAG05438.1 - 5.2e-12 45.2 0.8 1.4e-11 43.9 0.1 2.2 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG05438.1 - 2.2e-06 27.1 0.0 1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG05438.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.3 1 1 0 1 1 1 0 ECF sigma factor FecR PF04773.13 AAG05439.1 - 1.6e-21 76.7 0.2 2.7e-21 76.0 0.2 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG05439.1 - 1.9e-12 46.9 8.9 4.5e-12 45.7 8.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) Cyanate_lyase PF02560.14 AAG05440.1 - 9.1e-32 108.7 0.0 1.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 AAG05440.1 - 0.034 14.5 1.3 0.056 13.8 1.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 AAG05440.1 - 0.056 13.5 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix OAM_dimer PF16554.5 AAG05440.1 - 0.15 12.6 0.0 0.93 10.0 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Pro_CA PF00484.19 AAG05441.1 - 1.5e-51 174.8 0.2 1.7e-51 174.6 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase LysR_substrate PF03466.20 AAG05442.1 - 1.1e-43 149.0 11.5 2.1e-43 148.1 11.5 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05442.1 - 2.7e-25 88.1 2.0 2.7e-25 88.1 2.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG05442.1 - 8.8e-06 25.4 1.3 8.8e-06 25.4 1.3 2.3 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAG05442.1 - 0.0057 16.7 0.1 0.0057 16.7 0.1 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AAG05442.1 - 0.0071 16.2 0.2 0.019 14.8 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAG05442.1 - 0.023 14.6 0.8 0.023 14.6 0.8 3.5 4 0 0 4 4 4 0 MarR family HTH_23 PF13384.6 AAG05442.1 - 0.05 13.4 0.2 0.21 11.4 0.2 2.1 1 0 0 1 1 1 0 Homeodomain-like domain HTH_20 PF12840.7 AAG05442.1 - 0.066 13.3 1.2 0.066 13.3 1.2 3.2 3 1 0 3 3 3 0 Helix-turn-helix domain MarR PF01047.22 AAG05442.1 - 0.078 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AAG05442.1 - 0.097 12.3 0.0 0.35 10.5 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 AAG05443.1 - 1e-54 185.8 49.3 1.8e-53 181.7 46.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAG05443.1 - 1.7e-05 23.8 3.9 1.7e-05 23.8 3.9 2.2 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 AAG05443.1 - 0.3 9.3 8.0 0.043 12.1 0.4 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4231 PF14015.6 AAG05443.1 - 5 7.7 11.0 42 4.7 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) LysR_substrate PF03466.20 AAG05444.1 - 4.8e-34 117.5 5.0 8.4e-34 116.8 5.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05444.1 - 1.2e-20 73.2 2.9 3.4e-20 71.8 2.9 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family TonB_dep_Rec PF00593.24 AAG05445.1 - 2.3e-44 153.1 54.1 2.3e-44 153.1 54.1 2.5 1 1 2 3 3 3 1 TonB dependent receptor Plug PF07715.15 AAG05445.1 - 8.8e-23 80.9 1.7 8.8e-23 80.9 1.7 1.8 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain SBP_bac_5 PF00496.22 AAG05446.1 - 1.2e-70 238.4 0.0 2.3e-70 237.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 AAG05447.1 - 3.8e-34 118.0 9.8 6.6e-34 117.3 9.8 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component E1-E2_ATPase PF00122.20 AAG05447.1 - 5.2 6.6 6.1 34 3.9 3.0 2.3 2 0 0 2 2 2 0 E1-E2 ATPase BPD_transp_1 PF00528.22 AAG05448.1 - 3e-25 89.0 12.1 3e-25 89.0 12.1 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAG05448.1 - 0.0048 16.8 0.2 0.0048 16.8 0.2 3.5 4 1 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 AAG05449.1 - 9.9e-57 191.3 0.0 9.6e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAG05449.1 - 8.2e-15 55.4 3.6 4.1e-05 23.5 0.1 3.9 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG05449.1 - 5e-14 52.3 0.0 1.4e-05 24.7 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain oligo_HPY PF08352.12 AAG05449.1 - 5.7e-14 52.4 0.1 1.9e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 AAG05449.1 - 8.8e-09 36.0 10.4 3.8e-05 24.1 2.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AAG05449.1 - 3.6e-08 33.8 5.3 0.0023 18.2 0.6 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AAG05449.1 - 4.8e-08 32.6 0.2 0.003 17.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 AAG05449.1 - 7.8e-05 22.9 0.0 0.21 11.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AAG05449.1 - 0.00013 21.4 1.4 0.28 10.5 0.1 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AAG05449.1 - 0.00017 21.5 0.2 0.66 9.9 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 AAG05449.1 - 0.00036 20.2 3.9 1.5 8.4 0.1 4.1 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.12 AAG05449.1 - 0.00039 19.8 0.1 0.028 13.7 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 AAG05449.1 - 0.00042 19.9 0.0 0.63 9.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 AAG05449.1 - 0.0005 20.6 2.1 3.4 8.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.17 AAG05449.1 - 0.00056 20.1 1.0 0.42 10.7 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_5 PF07728.14 AAG05449.1 - 0.00076 19.5 3.7 0.57 10.2 0.2 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) TniB PF05621.11 AAG05449.1 - 0.0017 17.8 0.7 1.2 8.5 0.1 3.8 4 0 0 4 4 4 1 Bacterial TniB protein Sigma54_activat PF00158.26 AAG05449.1 - 0.0024 17.6 1.1 4.9 6.8 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2813 PF11398.8 AAG05449.1 - 0.0028 17.0 0.8 0.04 13.2 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) APS_kinase PF01583.20 AAG05449.1 - 0.0052 16.7 0.4 3.9 7.4 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase IstB_IS21 PF01695.17 AAG05449.1 - 0.0081 15.9 2.5 1.2 8.8 0.0 3.3 4 0 0 4 4 3 1 IstB-like ATP binding protein SbcCD_C PF13558.6 AAG05449.1 - 0.0088 16.3 0.2 5.4 7.3 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 AAG05449.1 - 0.012 15.5 3.0 2.6 7.9 0.1 3.1 3 0 0 3 3 2 0 NACHT domain MMR_HSR1 PF01926.23 AAG05449.1 - 0.013 15.5 0.3 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 AAG05449.1 - 0.02 14.6 0.0 8.6 6.0 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.6 AAG05449.1 - 0.023 15.2 0.0 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAG05449.1 - 0.025 15.0 0.2 7.3 7.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 AAG05449.1 - 0.062 12.7 0.4 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 AAG05449.1 - 0.064 13.7 0.0 23 5.4 0.0 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 AAG05449.1 - 0.066 12.8 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3987 PF13148.6 AAG05449.1 - 0.086 11.8 0.2 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 AAG05449.1 - 0.097 12.4 0.0 15 5.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 AAG05449.1 - 0.12 12.3 0.3 3.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 AAG05449.1 - 0.12 12.1 0.1 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.9 AAG05449.1 - 0.12 11.1 0.2 19 3.9 0.0 3.0 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AIG1 PF04548.16 AAG05449.1 - 0.13 11.6 0.9 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 AIG1 family TrwB_AAD_bind PF10412.9 AAG05449.1 - 0.17 10.8 0.3 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 AAG05449.1 - 0.17 12.1 0.3 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad51 PF08423.11 AAG05449.1 - 0.2 10.9 0.1 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Rad51 DUF815 PF05673.13 AAG05449.1 - 0.22 10.7 0.6 13 4.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase PF06745.13 AAG05449.1 - 0.23 10.8 0.1 7.2 5.9 0.0 2.2 2 0 0 2 2 2 0 KaiC Hpr_kinase_C PF07475.12 AAG05449.1 - 0.24 10.9 0.8 6.5 6.2 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Pox_A32 PF04665.12 AAG05449.1 - 0.29 10.6 0.7 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Aminotran_5 PF00266.19 AAG05450.1 - 1.1e-72 245.0 0.0 1.3e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAG05450.1 - 9.5e-06 24.4 0.0 1.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAG05450.1 - 0.004 16.5 0.1 0.0059 16.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_4 PF13439.6 AAG05450.1 - 0.054 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF2235 PF09994.9 AAG05451.1 - 2.2e-75 253.7 0.0 2.6e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CopB PF05275.11 AAG05452.1 - 7.8e-93 309.8 0.5 9.3e-93 309.6 0.5 1.1 1 0 0 1 1 1 1 Copper resistance protein B precursor (CopB) Autotransporter PF03797.19 AAG05452.1 - 0.00045 20.0 0.0 0.0093 15.6 0.0 2.3 1 1 0 1 1 1 1 Autotransporter beta-domain Cu-oxidase_3 PF07732.15 AAG05453.1 - 1.1e-48 164.1 0.0 3e-40 136.9 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 AAG05453.1 - 5.7e-34 117.5 0.0 6.3e-32 110.9 0.0 3.5 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AAG05453.1 - 4.1e-30 104.3 0.7 1.9e-25 89.2 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase TAT_signal PF10518.9 AAG05453.1 - 0.00086 19.1 2.2 0.0022 17.7 2.2 1.8 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence DUF218 PF02698.17 AAG05454.1 - 1.5e-14 54.1 0.0 1.8e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain HAD_2 PF13419.6 AAG05455.1 - 7.3e-22 78.3 0.0 8.6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG05455.1 - 4.4e-14 53.3 0.0 6.9e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG05455.1 - 2.2e-06 27.6 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like MFS_1_like PF12832.7 AAG05456.1 - 3.8e-39 134.7 11.1 1.5e-38 132.7 11.1 1.7 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 AAG05456.1 - 8.5e-24 84.1 50.8 3.7e-17 62.3 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 AAG05456.1 - 1.1e-11 44.4 7.7 3.8e-11 42.6 7.7 1.8 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 AAG05456.1 - 1.4e-05 24.0 11.4 0.0011 17.8 6.7 2.4 2 1 0 2 2 2 2 LacY proton/sugar symporter Carbam_trans_C PF16861.5 AAG05457.1 - 2.1e-53 180.4 0.0 3.1e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 AAG05457.1 - 7.5e-51 173.8 0.0 9.8e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Peptidase_M22 PF00814.25 AAG05457.1 - 6e-09 36.0 0.0 9.3e-05 22.3 0.0 2.8 3 0 0 3 3 3 2 Glycoprotease family Sua5_yciO_yrdC PF01300.18 AAG05457.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Telomere recombination TonB_dep_Rec PF00593.24 AAG05458.1 - 7.3e-54 184.4 36.3 7.3e-54 184.4 36.3 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG05458.1 - 1e-24 87.2 3.0 2.1e-24 86.1 3.0 1.5 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG05458.1 - 2.3e-05 23.6 0.0 4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family GTP_EFTU PF00009.27 AAG05459.1 - 1.9e-62 210.3 0.0 2.8e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AAG05459.1 - 1.8e-44 150.4 0.1 3.4e-44 149.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AAG05459.1 - 2.7e-35 120.3 0.1 5.8e-35 119.2 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AAG05459.1 - 8.1e-31 105.9 0.1 3.1e-30 104.1 0.1 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAG05459.1 - 3.8e-17 62.4 0.8 8.9e-17 61.2 0.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AAG05459.1 - 2e-06 27.7 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 AAG05459.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EAL PF00563.20 AAG05460.1 - 9.1e-67 225.0 0.0 1.8e-66 224.1 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG05460.1 - 6.2e-49 165.8 0.0 1.4e-48 164.7 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE4 PF05228.13 AAG05460.1 - 3.6e-19 69.3 0.2 7.9e-19 68.2 0.2 1.6 1 0 0 1 1 1 1 CHASE4 domain PAS_4 PF08448.10 AAG05460.1 - 0.00019 21.6 0.1 0.0031 17.8 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAG05460.1 - 0.001 19.0 0.0 0.0034 17.4 0.0 2.0 1 0 0 1 1 1 1 PAS fold DUF2244 PF10003.9 AAG05460.1 - 0.073 12.7 1.9 0.74 9.5 0.2 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Transp_cyt_pur PF02133.15 AAG05461.1 - 5.2e-54 183.7 36.4 6.3e-54 183.4 36.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CN_hydrolase PF00795.22 AAG05462.1 - 8.1e-44 149.9 0.0 9.1e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Bacillus_HBL PF05791.11 AAG05463.1 - 0.0049 16.7 8.2 0.0049 16.7 8.2 2.3 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 AAG05463.1 - 0.67 8.8 41.8 0.58 9.0 22.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 AAG05463.1 - 0.75 9.3 30.7 9.5 5.7 30.7 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 AAG05463.1 - 1.1 8.5 24.0 2.4 7.4 24.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 AAG05463.1 - 2.1 8.2 23.1 2.9 7.8 23.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3837 PF12939.7 AAG05463.1 - 2.3 8.6 6.5 11 6.4 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) RSS_P20 PF11757.8 AAG05463.1 - 6.2 7.3 9.8 8 7.0 1.2 2.9 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain LMBR1 PF04791.16 AAG05463.1 - 7.3 5.4 13.5 10 4.9 13.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LysR_substrate PF03466.20 AAG05464.1 - 4.4e-23 81.7 1.8 5.4e-23 81.5 1.8 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05464.1 - 2.6e-21 75.3 0.0 1.5e-20 72.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG05464.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 MarR family Cytochrome_CBB3 PF13442.6 AAG05465.1 - 5.2e-07 29.9 0.2 0.0034 17.7 0.0 3.4 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG05465.1 - 1.3e-05 26.2 0.1 0.088 14.0 0.0 3.3 3 0 0 3 3 3 2 Cytochrome c Paired_CXXCH_1 PF09699.10 AAG05465.1 - 0.03 14.1 0.7 9.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_C PF00034.21 AAG05466.1 - 4.1e-07 31.1 0.0 0.0029 18.7 0.1 3.5 3 0 0 3 3 3 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG05466.1 - 1.5e-06 28.5 0.0 0.00062 20.0 0.1 3.0 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C1 PF02167.15 AAG05466.1 - 0.013 15.2 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C1 family Cytochrom_C550 PF14495.6 AAG05466.1 - 0.024 14.3 0.1 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain AA_permease PF00324.21 AAG05467.1 - 1.4e-88 297.6 48.7 1.7e-88 297.3 48.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG05467.1 - 2.8e-34 118.7 50.7 3.4e-34 118.4 50.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4006 PF13179.6 AAG05467.1 - 0.45 10.4 0.0 0.45 10.4 0.0 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF4006) Aminotran_5 PF00266.19 AAG05468.1 - 2.9e-16 59.4 0.0 4.5e-16 58.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAG05468.1 - 0.00068 18.3 0.0 0.00093 17.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAG05468.1 - 0.0036 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AAA_30 PF13604.6 AAG05468.1 - 0.063 13.0 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cyclase PF04199.13 AAG05469.1 - 7.3e-18 65.1 0.0 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase AsnC_trans_reg PF01037.21 AAG05470.1 - 2.6e-22 78.6 0.1 3.7e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAG05470.1 - 3.2e-19 68.2 1.0 5.6e-19 67.4 1.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAG05470.1 - 3.6e-17 61.9 3.4 7.3e-17 60.9 3.4 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 AAG05470.1 - 5.4e-07 29.6 0.2 1.5e-06 28.1 0.3 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 AAG05470.1 - 2.7e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 AAG05470.1 - 7.7e-05 22.5 0.4 0.00016 21.5 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 AAG05470.1 - 8.2e-05 22.3 0.2 0.00018 21.2 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAG05470.1 - 0.00022 21.1 0.2 0.00044 20.1 0.2 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAG05470.1 - 0.00029 20.7 0.2 0.00087 19.2 0.2 1.8 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAG05470.1 - 0.00064 19.6 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_CodY PF08222.11 AAG05470.1 - 0.011 15.3 0.3 0.031 13.8 0.1 1.9 2 0 0 2 2 2 0 CodY helix-turn-helix domain Rrf2 PF02082.20 AAG05470.1 - 0.018 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_28 PF13518.6 AAG05470.1 - 0.025 14.7 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Rieske PF00355.26 AAG05471.1 - 7.2e-19 67.5 0.1 1.2e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 AAG05471.1 - 2.5e-17 63.5 0.0 7e-17 62.1 0.0 1.7 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Aromatic_hydrox PF11723.8 AAG05471.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase GATase PF00117.28 AAG05471.1 - 0.18 11.6 0.0 1.3 8.8 0.1 2.3 3 0 0 3 3 3 0 Glutamine amidotransferase class-I Asn_synthase PF00733.21 AAG05472.1 - 7.9e-96 321.8 0.1 9.9e-96 321.5 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAG05472.1 - 2.1e-45 153.6 0.0 3.8e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAG05472.1 - 7.7e-40 136.2 0.0 1.9e-39 134.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 AAG05472.1 - 0.066 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Ring_hydroxyl_B PF00866.18 AAG05473.1 - 3.6e-39 134.1 0.2 4.2e-39 133.9 0.2 1.0 1 0 0 1 1 1 1 Ring hydroxylating beta subunit Abhydrolase_1 PF00561.20 AAG05474.1 - 4.4e-20 72.4 0.0 5.2e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG05474.1 - 1.8e-13 51.6 14.7 2.3e-13 51.3 14.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG05474.1 - 7.5e-05 22.1 0.0 9.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 F-box_5 PF18511.1 AAG05474.1 - 0.16 11.5 0.7 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 F-box Ndr PF03096.14 AAG05474.1 - 0.17 10.5 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family Chlorophyllase PF07224.11 AAG05474.1 - 0.23 10.4 0.0 0.37 9.8 0.0 1.3 1 1 0 1 1 1 0 Chlorophyllase Methyltransf_25 PF13649.6 AAG05476.1 - 6.8e-14 52.4 0.0 1.3e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG05476.1 - 2.1e-12 47.5 0.0 3.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG05476.1 - 1.2e-08 34.9 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG05476.1 - 3.7e-08 33.3 0.0 4.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG05476.1 - 1e-06 29.4 0.0 1.5e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAG05476.1 - 0.00058 19.2 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 AAG05476.1 - 0.00078 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TonB_dep_Rec PF00593.24 AAG05477.1 - 9e-46 157.7 35.7 9e-46 157.7 35.7 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG05477.1 - 1.2e-23 83.7 1.2 3.8e-23 82.1 1.2 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG05477.1 - 6e-09 35.6 0.0 1.6e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain Bac_luciferase PF00296.20 AAG05478.1 - 3e-50 171.5 15.3 4e-50 171.0 15.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 AAG05479.1 - 3.5e-39 134.7 36.7 3.5e-39 134.7 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 AAG05480.1 - 1.2e-34 119.9 64.8 1.6e-23 83.2 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG05480.1 - 4e-09 36.3 38.1 4e-09 36.3 38.1 1.6 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AAG05480.1 - 2.1 6.5 9.2 0.099 10.9 0.4 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sigma70_r4 PF04545.16 AAG05481.1 - 2.9e-13 49.1 0.0 5.3e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG05481.1 - 1.2e-11 44.3 0.1 2.4e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAG05481.1 - 2.1e-11 43.3 0.0 3.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 AAG05481.1 - 0.0089 15.6 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 AAG05481.1 - 0.041 13.8 0.0 0.058 13.3 0.0 1.3 1 1 0 1 1 1 0 ECF sigma factor HTH_23 PF13384.6 AAG05481.1 - 0.092 12.6 0.0 0.32 10.9 0.0 2.0 1 1 0 1 1 1 0 Homeodomain-like domain DUF4880 PF16220.5 AAG05482.1 - 1.1e-12 47.7 2.3 2.4e-12 46.5 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) FecR PF04773.13 AAG05482.1 - 3.5e-12 46.8 0.0 5.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 FecR protein PPE PF00823.19 AAG05482.1 - 0.027 14.6 0.1 0.064 13.4 0.1 1.6 1 0 0 1 1 1 0 PPE family Arabinose_bd PF12625.7 AAG05484.1 - 1.9e-44 152.0 4.3 1.9e-44 152.0 4.3 2.0 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG05484.1 - 3.1e-17 62.6 0.8 6.6e-17 61.6 0.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05484.1 - 2.7e-10 40.1 0.0 4.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family FhuF PF06276.12 AAG05484.1 - 0.052 13.9 0.2 0.16 12.4 0.1 1.9 1 1 0 1 1 1 0 Ferric iron reductase FhuF-like transporter HTH_11 PF08279.12 AAG05484.1 - 0.1 12.6 0.5 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 HTH domain SurA_N PF09312.11 AAG05484.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain FMO-like PF00743.19 AAG05485.1 - 3.9e-21 75.1 0.0 9.2e-20 70.6 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 AAG05485.1 - 2.2e-19 69.8 0.0 9.6e-19 67.7 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAG05485.1 - 1.4e-17 63.9 0.0 7.5e-15 54.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AAG05485.1 - 2.5e-12 46.6 0.6 4.7e-10 39.1 0.0 3.1 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AAG05485.1 - 4.4e-12 46.0 0.1 5e-11 42.7 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAG05485.1 - 1.3e-06 28.5 1.1 0.0013 18.7 0.3 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 AAG05485.1 - 2.2e-06 27.5 4.1 0.004 16.8 1.2 3.0 1 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG05485.1 - 2e-05 23.9 0.3 0.00015 21.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AAG05485.1 - 2.5e-05 23.5 0.2 0.37 9.8 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 AAG05485.1 - 0.0001 21.7 0.3 0.0027 17.0 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AAG05485.1 - 0.00029 19.7 0.1 0.42 9.3 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 AAG05485.1 - 0.00043 19.7 0.3 0.58 9.4 0.0 2.4 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 AAG05485.1 - 0.031 13.4 0.1 0.19 10.8 0.1 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.27 AAG05485.1 - 0.05 14.2 0.8 1.1 9.9 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 AAG05486.1 - 6.5e-59 199.3 0.5 8.4e-59 199.0 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 AAG05486.1 - 3.1e-07 29.6 0.0 1.6e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase Thioesterase PF00975.20 AAG05486.1 - 3e-05 24.3 0.1 4.6e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 AAG05486.1 - 5.6e-05 22.5 0.0 0.071 12.4 0.0 2.7 1 1 2 3 3 3 2 Serine aminopeptidase, S33 UPF0227 PF05728.12 AAG05486.1 - 0.05 13.5 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) adh_short PF00106.25 AAG05487.1 - 7.8e-43 146.2 0.0 9.6e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG05487.1 - 1.2e-35 123.1 0.0 1.5e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG05487.1 - 1e-08 35.3 0.1 2.8e-08 33.9 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG05487.1 - 0.0011 18.5 0.0 0.0029 17.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Aminotran_1_2 PF00155.21 AAG05488.1 - 1.6e-24 86.8 0.0 2.2e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAG05488.1 - 1.3e-15 56.8 0.6 6.7e-15 54.5 0.2 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family DegT_DnrJ_EryC1 PF01041.17 AAG05488.1 - 1.1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HTH_24 PF13412.6 AAG05488.1 - 0.00014 21.4 0.0 0.00033 20.2 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAG05488.1 - 0.00016 21.6 1.6 0.0003 20.7 0.1 2.4 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAG05488.1 - 0.0021 17.9 0.4 0.026 14.4 0.1 2.8 2 0 0 2 2 2 1 MarR family Cys_Met_Meta_PP PF01053.20 AAG05488.1 - 0.0049 15.5 0.0 0.0072 14.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAG05488.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V MarR PF01047.22 AAG05488.1 - 0.017 15.1 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 AAG05488.1 - 0.024 14.8 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Aminotran_3 PF00202.21 AAG05488.1 - 0.059 12.0 0.1 0.21 10.2 0.1 1.7 1 1 0 1 1 1 0 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAG05488.1 - 0.17 11.1 0.1 0.31 10.3 0.1 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.7 AAG05488.1 - 0.18 10.5 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase HTH_IclR PF09339.10 AAG05488.1 - 0.64 9.9 3.8 0.65 9.8 0.1 2.9 3 0 0 3 3 2 0 IclR helix-turn-helix domain EamA PF00892.20 AAG05489.1 - 5.7e-41 139.9 50.3 1.7e-24 86.6 20.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 AAG05489.1 - 2.5e-05 23.7 6.7 2.5e-05 23.7 6.7 1.8 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport Prok-JAB PF14464.6 AAG05490.1 - 6.5e-18 64.6 0.0 8e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 AAG05490.1 - 0.022 14.7 0.1 0.22 11.5 0.1 2.0 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GTPase_binding PF09027.10 AAG05490.1 - 0.085 12.9 0.4 0.8 9.7 0.0 2.2 2 1 0 2 2 2 0 GTPase binding ThiF PF00899.21 AAG05491.1 - 4e-68 229.4 0.0 1.5e-67 227.5 0.0 1.7 2 0 0 2 2 2 1 ThiF family Rhodanese PF00581.20 AAG05491.1 - 2.3e-12 47.4 0.0 4.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 AAG05491.1 - 0.00092 19.3 0.1 0.12 12.5 0.0 2.6 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 AAG05491.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 AAG05491.1 - 0.15 12.5 0.0 4.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AAG05491.1 - 0.17 12.2 0.5 1.4 9.2 0.6 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PALP PF00291.25 AAG05492.1 - 2.4e-64 217.6 0.0 2.7e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hexapep PF00132.24 AAG05493.1 - 4.4e-16 57.9 7.9 3.5e-09 36.0 0.4 3.0 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAG05493.1 - 0.00014 21.5 11.8 0.0068 16.1 0.3 3.5 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase tRNA_SAD PF07973.14 AAG05494.1 - 2.8e-11 43.3 0.2 4.5e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 AAG05494.1 - 8e-09 34.5 0.0 9.4e-09 34.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DUF326 PF03860.16 AAG05495.1 - 5.5e-05 23.0 0.2 5.5e-05 23.0 0.2 4.4 4 0 0 4 4 4 3 Domain of Unknown Function (DUF326) TetR_C_15 PF17918.1 AAG05495.1 - 0.0073 17.0 6.7 0.28 12.0 0.5 2.6 1 1 2 3 3 3 2 Tetracyclin repressor-like, C-terminal domain MNNL PF07657.13 AAG05495.1 - 2.7 8.1 13.8 1.2 9.2 2.2 2.3 2 0 0 2 2 2 0 N terminus of Notch ligand TPP_enzyme_N PF02776.18 AAG05496.1 - 1.3e-46 158.3 1.4 1.3e-46 158.3 1.4 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAG05496.1 - 1.3e-28 99.7 0.3 5.9e-27 94.3 0.0 3.0 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG05496.1 - 1.8e-28 99.0 0.1 9e-28 96.7 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AAG05496.1 - 0.00014 21.7 0.4 0.00024 21.0 0.4 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF4142 PF13628.6 AAG05497.1 - 1.2e-21 77.4 6.5 1.7e-21 76.9 6.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) DUF1887 PF09002.11 AAG05497.1 - 0.0089 14.8 0.3 0.011 14.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) DUF305 PF03713.13 AAG05497.1 - 0.033 14.3 2.1 0.27 11.3 2.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF305) Defensin_propep PF00879.18 AAG05497.1 - 0.56 10.5 6.8 1.5 9.1 6.8 1.8 1 0 0 1 1 1 0 Defensin propeptide CT_A_B PF02626.15 AAG05498.1 - 3.3e-77 259.7 0.3 3.9e-77 259.4 0.3 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 AAG05499.1 - 4.7e-60 202.8 0.0 5.3e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D LamB_YcsF PF03746.16 AAG05500.1 - 9e-97 323.4 0.0 1e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family OprD PF03573.13 AAG05501.1 - 1.2e-145 485.5 1.1 1.3e-145 485.4 1.1 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Porin_4 PF13609.6 AAG05501.1 - 0.0078 16.0 9.3 0.011 15.5 6.2 2.5 1 1 1 2 2 2 1 Gram-negative porin TGF_beta_GS PF08515.12 AAG05501.1 - 0.5 9.9 5.2 3.1 7.4 0.1 2.6 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif MFS_1 PF07690.16 AAG05502.1 - 3.3e-39 134.8 51.3 6.5e-31 107.5 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG05502.1 - 6.8e-27 94.4 23.4 3e-19 69.2 6.7 2.6 1 1 1 3 3 3 3 Sugar (and other) transporter LysR_substrate PF03466.20 AAG05503.1 - 7.2e-36 123.5 2.6 1.1e-35 122.9 2.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05503.1 - 1.3e-17 63.5 0.1 2.7e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF1445 PF07286.12 AAG05504.1 - 3.4e-59 198.9 0.0 4.5e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MSA-2c PF12238.8 AAG05505.1 - 0.15 12.1 2.3 0.21 11.5 2.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DNA_binding_1 PF01035.20 AAG05506.1 - 4e-32 110.2 1.0 4e-32 110.2 1.0 2.5 2 1 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.16 AAG05506.1 - 3.9e-30 103.7 2.5 9e-30 102.5 2.5 1.7 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 AAG05506.1 - 4.9e-20 71.6 1.8 4.9e-20 71.6 1.8 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05506.1 - 6.2e-12 45.3 0.0 2.8e-09 36.9 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Methyltransf_1N PF02870.15 AAG05506.1 - 0.0052 17.6 0.0 0.0099 16.7 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain ADH_zinc_N PF00107.26 AAG05507.1 - 1.8e-26 92.6 0.0 2.6e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG05507.1 - 4.3e-21 74.9 0.1 4.4e-20 71.6 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AAG05507.1 - 6.7e-11 43.4 0.0 1e-10 42.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 AAG05507.1 - 0.13 12.9 0.0 0.35 11.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain SnoaL_2 PF12680.7 AAG05508.1 - 4.9e-09 36.7 0.1 7.1e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAG05508.1 - 0.0031 17.3 0.1 0.023 14.5 0.1 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase LysR_substrate PF03466.20 AAG05509.1 - 6.2e-29 100.9 8.0 6.2e-29 100.9 8.0 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05509.1 - 1.4e-18 66.6 2.1 2.9e-18 65.6 2.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Polyketide_cyc2 PF10604.9 AAG05510.1 - 3e-23 82.7 0.3 4.6e-23 82.1 0.3 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FA_hydroxylase PF04116.13 AAG05510.1 - 9.8e-11 42.1 12.4 1.8e-10 41.3 12.4 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily LysR_substrate PF03466.20 AAG05511.1 - 8e-43 146.2 5.5 1.1e-42 145.8 5.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05511.1 - 8.4e-18 64.1 2.0 1.5e-17 63.3 0.6 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAG05511.1 - 4.3e-05 23.5 1.6 0.00037 20.5 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG05511.1 - 0.0028 17.5 0.3 0.0088 15.9 0.3 1.8 1 0 0 1 1 1 1 MarR family HTH_AsnC-type PF13404.6 AAG05511.1 - 0.0041 16.9 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 AAG05511.1 - 0.0065 16.6 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAG05511.1 - 0.022 14.6 0.7 0.099 12.5 0.1 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AAG05511.1 - 0.041 13.4 0.1 0.094 12.3 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AAG05511.1 - 0.065 12.8 0.2 0.065 12.8 0.2 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_30 PF13556.6 AAG05511.1 - 0.076 12.8 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF2802 PF10975.8 AAG05511.1 - 0.12 12.6 0.3 0.31 11.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Sigma70_r4_2 PF08281.12 AAG05511.1 - 0.12 12.0 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AAG05511.1 - 0.13 12.2 1.4 0.94 9.5 0.7 2.4 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain GMC_oxred_N PF00732.19 AAG05512.1 - 9.8e-62 209.0 0.0 1.3e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AAG05512.1 - 1.3e-37 129.6 0.0 2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 AAG05512.1 - 6e-07 29.4 0.2 5.3e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG05512.1 - 3.3e-06 26.5 0.7 0.0013 17.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 AAG05512.1 - 9.5e-05 21.6 0.0 0.038 13.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAG05512.1 - 0.00025 21.2 2.2 0.00059 20.0 0.7 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAG05512.1 - 0.00044 19.6 0.2 0.00078 18.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAG05512.1 - 0.00047 19.5 0.0 0.66 9.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAG05512.1 - 0.00063 18.9 0.2 0.0016 17.6 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AAG05512.1 - 0.0013 18.1 0.1 0.0086 15.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAG05512.1 - 0.0031 16.9 0.6 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 AAG05512.1 - 0.0041 15.9 0.1 0.031 13.0 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 AAG05512.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Aldedh PF00171.22 AAG05513.1 - 4.5e-141 470.5 0.0 5.3e-141 470.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AAG05513.1 - 0.00036 20.0 0.0 0.71 9.3 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1487) ParBc PF02195.18 AAG05514.1 - 8e-13 48.5 0.1 1.5e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain DUF3440 PF11922.8 AAG05515.1 - 1.3e-29 103.2 0.0 1.9e-25 89.6 0.0 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF3440) PAPS_reduct PF01507.19 AAG05515.1 - 4.7e-16 59.3 0.0 1.2e-14 54.7 0.0 2.4 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 AAG05515.1 - 0.093 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PP-loop family FimA PF16970.5 AAG05516.1 - 0.00019 21.6 5.9 0.00019 21.6 5.9 2.1 2 1 0 2 2 2 1 Type-1 fimbrial protein, A DUF2574 PF10836.8 AAG05516.1 - 0.88 9.5 6.7 0.82 9.6 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2574) PapD_N PF00345.20 AAG05517.1 - 2.9e-41 140.3 0.0 4.3e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAG05517.1 - 5.9e-13 49.0 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain Usher PF00577.20 AAG05518.1 - 3.4e-144 481.7 10.6 8.2e-143 477.2 10.6 2.0 1 1 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AAG05518.1 - 2.3e-40 137.9 0.0 4e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AAG05518.1 - 4.5e-21 74.4 0.1 1.1e-20 73.2 0.1 1.7 1 0 0 1 1 1 1 PapC C-terminal domain Fimbrial PF00419.20 AAG05519.1 - 5.9e-29 101.3 0.0 1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 Fimbrial protein PapD_N PF00345.20 AAG05520.1 - 4.9e-37 126.6 0.0 7.3e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAG05520.1 - 1.9e-12 47.4 0.0 5.9e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain NAPRTase_C PF17956.1 AAG05520.1 - 0.067 13.6 0.0 0.2 12.1 0.0 1.7 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain EAL PF00563.20 AAG05521.1 - 1.6e-40 139.1 0.0 1.9e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 EAL domain DUF4142 PF13628.6 AAG05522.1 - 1.4e-40 138.8 12.3 1.7e-40 138.5 12.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) DUF2383 PF09537.10 AAG05522.1 - 4e-05 23.9 1.5 0.013 15.9 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2383) DUF305 PF03713.13 AAG05522.1 - 0.00021 21.5 3.1 0.0075 16.4 2.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF305) Na_H_Exchanger PF00999.21 AAG05523.1 - 5.4e-33 114.3 27.0 2.4e-26 92.5 18.1 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Response_reg PF00072.24 AAG05525.1 - 5.1e-05 23.4 0.0 9.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Response regulator receiver domain LigD_N PF13298.6 AAG05526.1 - 3.2e-39 133.4 0.0 5.5e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) DNA_ligase_A_C PF04679.15 AAG05526.1 - 2.8e-24 85.6 0.1 1.2e-23 83.6 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.21 AAG05526.1 - 1.2e-22 80.5 0.0 1.9e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_primase_S PF01896.19 AAG05526.1 - 0.0086 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit Metallothio_Pro PF02069.16 AAG05528.1 - 3.9e-13 49.4 20.6 5e-13 49.1 20.6 1.2 1 0 0 1 1 1 1 Prokaryotic metallothionein CinA PF02464.17 AAG05529.1 - 6.7e-36 123.2 0.0 8.5e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein ACR_tran PF00873.19 AAG05529.1 - 0.16 9.6 0.0 0.2 9.3 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family adh_short_C2 PF13561.6 AAG05530.1 - 3.6e-67 226.3 0.0 4.5e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG05530.1 - 4.2e-54 183.0 0.0 5e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG05530.1 - 4.5e-12 46.2 0.0 5.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AAG05530.1 - 0.0025 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AAG05530.1 - 0.0031 17.0 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AAG05530.1 - 0.0073 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 AAG05530.1 - 0.096 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2513 PF10711.9 AAG05531.1 - 2.2e-17 63.3 0.0 2.6e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Hypothetical protein (DUF2513) Phosphorylase PF00343.20 AAG05532.1 - 6e-296 983.4 0.0 6.9e-296 983.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase KGG PF10685.9 AAG05534.1 - 1.2e-17 63.5 15.4 1.2e-09 38.1 3.3 2.6 3 0 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif Catalase PF00199.19 AAG05535.1 - 7.4e-181 601.4 0.0 9.3e-181 601.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AAG05535.1 - 1.8e-20 72.9 0.4 3.4e-20 72.0 0.4 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 AAG05535.1 - 9.5e-20 70.8 0.0 1.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 AAG05535.1 - 4e-12 46.2 0.0 6.2e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family MgtC PF02308.16 AAG05536.1 - 2.9e-35 121.3 15.1 3.3e-35 121.1 15.1 1.0 1 0 0 1 1 1 1 MgtC family Rnf-Nqr PF02508.14 AAG05536.1 - 0.57 10.1 4.8 1 9.3 4.8 1.6 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein CPBP PF02517.16 AAG05536.1 - 0.97 9.8 3.8 2.8 8.4 0.0 2.4 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease DUF2157 PF09925.9 AAG05536.1 - 1.1 9.0 12.2 2.7 7.8 0.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Ku PF02735.16 AAG05538.1 - 2.4e-35 122.1 0.0 3e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain DUF3416 PF11896.8 AAG05539.1 - 1.6e-46 158.9 0.1 2.6e-46 158.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Alpha-amylase PF00128.24 AAG05539.1 - 2.3e-06 27.4 0.0 4.5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL6 PF14871.6 AAG05539.1 - 0.028 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Alpha-amylase PF00128.24 AAG05540.1 - 1.6e-69 235.0 0.0 3.4e-69 234.0 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 AAG05540.1 - 1.3e-27 95.7 0.0 2.6e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Mak_N_cap PF18085.1 AAG05540.1 - 2.3e-05 25.3 0.0 0.0002 22.4 0.0 2.7 2 0 0 2 2 2 1 Maltokinase N-terminal cap domain Apolipoprotein PF01442.18 AAG05540.1 - 0.0089 15.9 0.5 0.021 14.7 0.5 1.6 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CBM_48 PF02922.18 AAG05541.1 - 3.2e-27 94.7 0.0 1.2e-22 80.1 0.0 2.6 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 AAG05541.1 - 2e-21 76.3 0.0 3.5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 AAG05541.1 - 3e-12 46.7 0.0 7.1e-09 35.7 0.0 2.2 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 AAG05541.1 - 0.013 13.7 0.0 0.019 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 AMPK1_CBM PF16561.5 AAG05541.1 - 0.16 12.2 0.7 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase T2SSL PF05134.13 AAG05541.1 - 0.18 11.1 0.1 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein L LPG_synthase_TM PF03706.13 AAG05542.1 - 3.5e-13 49.8 40.0 6.2e-13 48.9 40.0 1.4 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region PLDc_2 PF13091.6 AAG05543.1 - 2.1e-41 140.9 0.0 1.1e-24 86.8 0.0 2.4 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 AAG05543.1 - 1.7e-11 43.8 0.3 0.00013 22.0 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 AAG05543.1 - 7.2e-06 25.4 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB PP_kinase_C PF13090.6 AAG05543.1 - 0.037 13.5 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Polyphosphate kinase C-terminal domain 2 Exo_endo_phos PF03372.23 AAG05544.1 - 3.5e-11 43.1 1.0 5.6e-11 42.4 1.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF72 PF01904.18 AAG05545.1 - 5e-67 226.2 0.4 5.8e-67 226.0 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 ADH_N PF08240.12 AAG05546.1 - 2.4e-26 91.8 0.4 4.9e-26 90.7 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAG05546.1 - 1.7e-14 53.9 0.0 4.7e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAG05546.1 - 9.2e-05 21.8 0.1 0.00015 21.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 AAG05546.1 - 0.00041 20.2 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.18 AAG05546.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAG05546.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBS PF00571.28 AAG05547.1 - 2.3e-21 76.0 0.9 1.3e-10 41.6 0.2 2.1 2 0 0 2 2 2 2 CBS domain CBM_48 PF02922.18 AAG05548.1 - 3.9e-21 75.2 0.0 5.1e-20 71.6 0.0 2.2 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 AAG05548.1 - 4.5e-13 49.5 0.0 2.3e-08 34.0 0.0 3.0 2 1 1 3 3 3 2 Alpha amylase, catalytic domain DUF3459 PF11941.8 AAG05548.1 - 0.063 13.6 1.9 5.2 7.5 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3459) DUF2934 PF11154.8 AAG05549.1 - 1.2e-14 53.7 7.6 2.1e-14 52.9 7.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2934) Nucleo_P87 PF07267.11 AAG05549.1 - 0.0052 15.7 2.7 0.0055 15.6 2.7 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 Alpha-amylase PF00128.24 AAG05550.1 - 4.9e-19 69.1 0.0 4.6e-15 56.0 0.0 2.9 3 0 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_hydro_77 PF02446.17 AAG05551.1 - 1e-107 360.9 0.0 1.3e-107 360.6 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase DUF3459 PF11941.8 AAG05552.1 - 1.8e-16 60.2 0.7 5.1e-16 58.8 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase PF00128.24 AAG05552.1 - 6.8e-15 55.5 0.0 2.2e-08 34.0 0.0 3.1 2 1 1 3 3 3 3 Alpha amylase, catalytic domain CBM_48 PF02922.18 AAG05552.1 - 7e-08 32.7 0.0 2.4e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Aminotran_1_2 PF00155.21 AAG05552.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II GHL5 PF14872.6 AAG05552.1 - 0.26 9.3 0.0 1.7 6.6 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycoside hydrolase 5 Glyco_transf_5 PF08323.11 AAG05553.1 - 1.5e-65 221.3 0.0 2.3e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AAG05553.1 - 4e-15 55.8 0.0 6.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG05553.1 - 2.7e-11 44.0 0.0 4.4e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAG05553.1 - 4.9e-08 33.6 0.9 1.2e-07 32.3 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAG05553.1 - 1e-05 25.6 0.5 6.4e-05 23.0 0.5 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF3509 PF12021.8 AAG05554.1 - 2.9e-14 52.6 0.3 7e-14 51.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) DUF3182 PF11379.8 AAG05555.1 - 1.2e-141 471.8 0.4 1.3e-141 471.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3182) Peptidase_S9 PF00326.21 AAG05556.1 - 2e-12 47.1 0.1 1.9e-11 43.8 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AAG05556.1 - 1.7e-10 41.9 5.1 3.2e-10 41.0 5.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG05556.1 - 9.8e-10 38.1 1.3 9.3e-09 34.9 0.2 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG05556.1 - 2.3e-07 30.7 0.8 1.7e-06 27.9 0.2 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold UPF0227 PF05728.12 AAG05556.1 - 2.5e-06 27.6 0.0 4.9e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) AXE1 PF05448.12 AAG05556.1 - 6.3e-06 25.1 0.1 0.021 13.5 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 AAG05556.1 - 9.6e-05 22.1 0.1 0.0041 16.8 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 AAG05556.1 - 0.00038 20.4 0.0 0.00079 19.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 AAG05556.1 - 0.0013 18.3 0.1 0.0071 15.9 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2920 PF11144.8 AAG05556.1 - 0.0049 16.1 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_4 PF08386.10 AAG05556.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein PAF-AH_p_II PF03403.13 AAG05556.1 - 0.12 10.8 0.0 2.4 6.6 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 AAG05556.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2383 PF09537.10 AAG05557.1 - 3.5e-40 136.8 0.2 4.7e-40 136.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) Ferritin PF00210.24 AAG05557.1 - 0.015 15.2 0.1 0.035 14.1 0.1 1.8 1 1 1 2 2 2 0 Ferritin-like domain Coat_F PF07875.12 AAG05557.1 - 0.017 15.4 0.3 0.079 13.2 0.0 1.9 2 0 0 2 2 2 0 Coat F domain DUF892 PF05974.12 AAG05557.1 - 0.017 15.1 0.2 0.035 14.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF892) PLDc_N PF13396.6 AAG05558.1 - 5.6e-10 39.0 3.7 5.6e-10 39.0 3.7 1.4 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal FixS PF03597.15 AAG05558.1 - 6.5 6.6 11.9 0.74 9.6 1.1 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Hemerythrin PF01814.23 AAG05559.1 - 1.7e-17 64.3 8.4 1.7e-17 64.3 8.4 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Peptidase_M42 PF05343.14 AAG05560.1 - 7e-39 133.6 0.0 8.5e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 AAG05560.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2892 PF11127.8 AAG05561.1 - 7.3e-08 32.3 0.1 9.5e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) TolA_bind_tri PF16331.5 AAG05561.1 - 0.02 15.0 5.3 0.028 14.5 5.3 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation SlyX PF04102.12 AAG05561.1 - 0.059 14.0 3.4 0.083 13.5 3.4 1.2 1 0 0 1 1 1 0 SlyX DUF5320 PF17253.2 AAG05561.1 - 0.13 13.4 0.5 0.2 12.8 0.5 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5320) FixQ PF05545.11 AAG05563.1 - 0.2 11.6 3.3 2.4 8.2 0.4 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ CbtB PF09489.10 AAG05563.1 - 0.98 9.6 9.2 4.5 7.5 1.1 2.6 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtB) NAD_binding_10 PF13460.6 AAG05564.1 - 8.8e-06 25.7 0.0 3.7e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding PAS_9 PF13426.7 AAG05565.1 - 8.3e-29 99.9 0.0 1.9e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAG05565.1 - 2.1e-24 85.7 0.0 3.5e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAG05565.1 - 1.8e-20 73.2 3.7 7.2e-11 42.3 0.1 2.9 3 0 0 3 3 3 2 PAS fold HATPase_c PF02518.26 AAG05565.1 - 2e-18 66.9 0.0 5.6e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAG05565.1 - 1.9e-15 56.9 0.2 6.5e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold Response_reg PF00072.24 AAG05565.1 - 6.2e-14 52.1 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAG05565.1 - 1.3e-09 37.9 2.3 6.5e-09 35.7 0.2 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 AAG05565.1 - 0.00028 21.4 0.0 0.21 12.2 0.0 2.3 2 0 0 2 2 2 2 PAS domain MEKHLA PF08670.11 AAG05565.1 - 0.00064 19.6 0.5 0.37 10.7 0.1 2.8 3 0 0 3 3 2 2 MEKHLA domain PAS_8 PF13188.7 AAG05565.1 - 0.014 15.4 0.0 1.9 8.6 0.0 3.2 3 0 0 3 3 3 0 PAS domain HPTransfase PF10090.9 AAG05565.1 - 0.041 13.7 0.1 0.3 10.9 0.0 2.5 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 AAG05565.1 - 0.096 12.5 0.0 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAG05565.1 - 0.11 12.4 0.0 4.3 7.3 0.0 2.3 2 0 0 2 2 2 0 GHKL domain Rbx_binding PF18113.1 AAG05565.1 - 0.13 12.1 0.1 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain DUF1282 PF06930.12 AAG05566.1 - 1.8e-18 66.9 6.3 2.2e-18 66.6 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Yip1 PF04893.17 AAG05566.1 - 2.6e-17 63.1 18.7 3.3e-17 62.7 18.7 1.2 1 0 0 1 1 1 1 Yip1 domain 7TMR-DISM_7TM PF07695.11 AAG05566.1 - 0.0056 16.6 2.2 0.0056 16.6 2.2 2.5 1 1 1 2 2 2 1 7TM diverse intracellular signalling MTS PF05175.14 AAG05567.1 - 3.5e-16 59.2 0.0 8.3e-16 58.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAG05567.1 - 3.3e-13 49.7 0.0 4.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG05567.1 - 1.4e-09 38.6 0.0 4.4e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG05567.1 - 9.5e-08 32.7 0.0 2.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAG05567.1 - 7e-06 25.6 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 AAG05567.1 - 1.5e-05 24.8 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 AAG05567.1 - 5.1e-05 23.8 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 AAG05567.1 - 0.00098 18.5 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_4 PF02390.17 AAG05567.1 - 0.002 17.6 0.0 0.0046 16.4 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Met_10 PF02475.16 AAG05567.1 - 0.045 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.10 AAG05567.1 - 0.064 12.8 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GidB PF02527.15 AAG05567.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Haem_oxygenas_2 PF14518.6 AAG05568.1 - 2.8e-33 115.2 0.5 5.8e-33 114.1 0.5 1.6 1 0 0 1 1 1 1 Iron-containing redox enzyme GCS2 PF04107.13 AAG05569.1 - 1.2e-88 297.3 0.2 1.2e-88 297.3 0.2 1.7 2 0 0 2 2 2 1 Glutamate-cysteine ligase family 2(GCS2) DUF2061 PF09834.9 AAG05571.1 - 1.3e-23 83.3 1.0 1.5e-23 83.0 1.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2061) Promethin PF16015.5 AAG05571.1 - 0.087 12.7 2.4 0.11 12.4 2.4 1.1 1 0 0 1 1 1 0 Promethin DUF892 PF05974.12 AAG05572.1 - 1.8e-50 171.0 6.5 2.1e-50 170.9 6.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF892) Rubrerythrin PF02915.17 AAG05572.1 - 8e-05 23.1 0.4 0.00012 22.5 0.4 1.3 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 AAG05572.1 - 0.0016 18.4 5.5 0.035 14.0 4.8 2.2 1 1 0 1 1 1 1 Ferritin-like domain Vir_act_alpha_C PF10400.9 AAG05572.1 - 0.31 11.7 7.2 8.7 7.1 0.0 2.9 2 1 1 3 3 3 0 Virulence activator alpha C-term Mn_catalase PF05067.12 AAG05573.1 - 4.5e-115 383.5 0.0 5e-115 383.3 0.0 1.0 1 0 0 1 1 1 1 Manganese containing catalase Rubrerythrin PF02915.17 AAG05573.1 - 0.053 13.9 0.0 7.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Rubrerythrin Iron_permease PF04120.12 AAG05575.1 - 8e-51 171.1 0.0 9.1e-51 171.0 0.0 1.0 1 0 0 1 1 1 1 Low affinity iron permease SLATT_4 PF18186.1 AAG05575.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 ADH_N PF08240.12 AAG05576.1 - 2.9e-29 101.1 0.0 7.2e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAG05576.1 - 1.2e-11 44.7 3.3 8.1e-10 38.8 0.1 2.7 2 1 1 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 AAG05576.1 - 9.4e-08 31.9 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 AAG05576.1 - 0.00065 19.1 0.4 0.0011 18.4 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AAG05576.1 - 0.011 15.0 0.5 0.18 11.0 0.5 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 AAG05576.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AAG05576.1 - 0.023 15.7 0.6 0.15 13.2 0.6 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 AAG05576.1 - 0.037 14.6 0.1 0.93 10.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG05576.1 - 0.048 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ATPgrasp_N PF18130.1 AAG05576.1 - 0.083 13.5 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp N-terminal domain HI0933_like PF03486.14 AAG05576.1 - 0.09 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 AAG05576.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CLP_protease PF00574.23 AAG05577.1 - 6.9e-15 55.4 0.0 7.7e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Clp protease KGG PF10685.9 AAG05578.1 - 1.8e-37 126.5 54.7 4.4e-11 42.7 5.0 5.7 6 0 0 6 6 6 5 Stress-induced bacterial acidophilic repeat motif LEA_5 PF00477.17 AAG05578.1 - 0.0021 18.5 8.0 0.0021 18.5 8.0 2.2 1 1 1 2 2 2 2 Small hydrophilic plant seed protein Anthrax_toxA PF03497.16 AAG05579.1 - 3.7e-68 229.1 0.0 4.9e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Anthrax toxin LF subunit CBS PF00571.28 AAG05580.1 - 1.6e-20 73.3 1.1 3.1e-12 46.7 0.2 2.1 2 0 0 2 2 2 2 CBS domain DUF1150 PF06620.11 AAG05580.1 - 0.0047 17.0 0.2 0.11 12.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1150) Fer2_4 PF13510.6 AAG05581.1 - 2.9e-22 78.5 1.8 3.4e-22 78.3 1.8 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAG05581.1 - 0.00011 22.2 0.1 0.00013 21.9 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AAG05581.1 - 0.00013 21.8 5.2 0.00048 20.0 5.2 1.8 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AAG05581.1 - 0.085 12.7 6.5 0.14 12.0 6.5 1.3 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Pyr_redox_2 PF07992.14 AAG05582.1 - 3.1e-22 79.2 0.0 1.8e-21 76.7 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AAG05582.1 - 8.3e-12 45.3 3.6 8.3e-12 45.3 3.6 1.9 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NAD_binding_8 PF13450.6 AAG05582.1 - 3.6e-09 36.7 0.2 1.2e-08 35.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AAG05582.1 - 3.3e-07 29.7 1.9 0.00017 20.8 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAG05582.1 - 2.9e-06 26.9 0.5 9.4e-06 25.2 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase SO_alpha_A3 PF17806.1 AAG05582.1 - 1.5e-05 25.3 0.0 6.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Sarcosine oxidase A3 domain FAD_binding_2 PF00890.24 AAG05582.1 - 1.7e-05 24.1 0.4 3.1e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAG05582.1 - 2.2e-05 24.2 1.4 0.0001 22.0 1.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG05582.1 - 0.00025 19.9 0.1 0.00064 18.5 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 AAG05582.1 - 0.00098 18.5 0.4 0.00098 18.5 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AAG05582.1 - 0.0028 18.2 0.0 0.89 10.2 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG05582.1 - 0.0068 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 AAG05582.1 - 0.023 14.0 1.2 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AAG05582.1 - 0.032 13.5 0.4 0.054 12.7 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAG05582.1 - 0.11 11.5 2.1 6.8 5.6 0.4 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAG05582.1 - 0.29 11.1 3.3 0.15 12.0 0.3 2.0 3 0 0 3 3 2 0 FAD-NAD(P)-binding DAO PF01266.24 AAG05583.1 - 2.7e-67 227.9 1.7 3.2e-67 227.6 1.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG05583.1 - 9.5e-08 31.5 7.9 1.5e-05 24.3 3.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 AAG05583.1 - 8.6e-07 28.5 0.2 0.0093 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG05583.1 - 2.4e-05 24.8 0.0 0.11 13.1 0.1 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG05583.1 - 0.00018 20.8 0.5 0.00067 19.0 0.4 1.8 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 AAG05583.1 - 0.00025 20.5 0.4 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG05583.1 - 0.0005 18.9 0.2 0.15 10.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 AAG05583.1 - 0.0015 18.8 0.5 0.0032 17.6 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 AAG05583.1 - 0.0015 17.9 0.1 0.53 9.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_3 PF13738.6 AAG05583.1 - 0.014 14.7 0.0 1.4 8.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AAG05583.1 - 0.029 13.2 0.2 3.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 AAG05583.1 - 0.056 13.4 1.4 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AAG05583.1 - 0.1 12.9 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TetR_N PF00440.23 AAG05584.1 - 4.4e-13 48.8 0.0 6.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 AAG05584.1 - 1.2e-10 41.4 0.0 1.8e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAG05584.1 - 0.0031 17.7 0.1 0.0047 17.1 0.1 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal DUF2755 PF10954.8 AAG05584.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) ADH_N_2 PF16884.5 AAG05585.1 - 9.8e-44 147.7 0.0 1.7e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 AAG05585.1 - 1.3e-17 63.9 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAG05585.1 - 1.5e-11 45.4 0.0 2.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ABM PF03992.16 AAG05586.1 - 3.7e-20 71.8 0.2 4.9e-20 71.4 0.2 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NAD_binding_2 PF03446.15 AAG05587.1 - 4.5e-34 117.9 0.5 6.6e-34 117.4 0.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAG05587.1 - 1.9e-18 66.8 0.0 3.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 AAG05587.1 - 4e-05 23.0 0.1 5.7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAG05587.1 - 0.00017 22.1 0.3 0.00039 20.9 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AAG05587.1 - 0.0002 21.0 0.4 0.00034 20.3 0.4 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAG05587.1 - 0.00064 19.7 0.3 0.0012 18.7 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAG05587.1 - 0.01 15.9 0.2 0.021 14.8 0.2 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 AAG05587.1 - 0.012 15.7 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_trans_4_4 PF13579.6 AAG05587.1 - 0.014 15.9 1.0 0.024 15.1 1.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain adh_short PF00106.25 AAG05587.1 - 0.019 14.4 0.0 0.16 11.4 0.1 2.0 2 0 0 2 2 2 0 short chain dehydrogenase GST_C_6 PF17171.4 AAG05587.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sacchrp_dh_NADP PF03435.18 AAG05587.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.6 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 AAG05587.1 - 0.2 12.1 0.3 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding EAL PF00563.20 AAG05588.1 - 2.5e-55 187.6 0.0 3.6e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 EAL domain CSS-motif PF12792.7 AAG05588.1 - 3.7e-35 121.3 0.0 7.8e-35 120.3 0.0 1.5 2 0 0 2 2 2 1 CSS motif domain associated with EAL DUF1911 PF08929.10 AAG05589.1 - 2.2e-23 83.1 0.0 3.5e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1911) BPD_transp_1 PF00528.22 AAG05590.1 - 2.5e-22 79.5 17.2 2.5e-22 79.5 17.2 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG05591.1 - 1.6e-13 50.8 6.4 1.6e-13 50.8 6.4 1.5 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 AAG05591.1 - 0.35 11.4 6.8 0.61 10.6 0.8 2.4 2 0 0 2 2 2 0 FtsX-like permease family SBP_bac_3 PF00497.20 AAG05592.1 - 6.9e-60 202.3 0.0 7.9e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG05592.1 - 6.8e-08 32.7 0.0 1.3e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site LysR_substrate PF03466.20 AAG05594.1 - 1.1e-39 136.0 1.5 1.4e-39 135.6 1.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05594.1 - 2.8e-17 62.4 0.4 2.8e-17 62.4 0.4 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family TctA PF01970.16 AAG05595.1 - 2.3e-135 451.5 38.8 2.3e-135 451.5 38.8 1.5 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctA family TctB PF07331.11 AAG05596.1 - 1.3e-16 61.1 13.5 1.6e-16 60.8 13.5 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family TctC PF03401.14 AAG05597.1 - 4.6e-12 45.6 0.0 5.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor MFS_1 PF07690.16 AAG05598.1 - 3.2e-49 167.7 45.6 3.2e-49 167.7 45.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2561 PF10812.8 AAG05598.1 - 0.016 15.2 0.3 0.042 13.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) OATP PF03137.20 AAG05598.1 - 0.17 10.2 10.2 0.55 8.5 0.4 3.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Amidohydro_2 PF04909.14 AAG05599.1 - 1.7e-39 136.3 11.1 2e-39 136.1 11.1 1.0 1 0 0 1 1 1 1 Amidohydrolase PdxA PF04166.12 AAG05600.1 - 7.7e-82 274.9 0.0 9.2e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA OprD PF03573.13 AAG05601.1 - 1.7e-156 521.2 1.2 2e-156 521.0 1.2 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Porin_4 PF13609.6 AAG05601.1 - 0.0096 15.7 6.3 0.015 15.0 5.5 1.7 1 1 0 1 1 1 1 Gram-negative porin MFS_1 PF07690.16 AAG05602.1 - 2.1e-42 145.3 38.9 3.1e-42 144.8 38.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MR_MLE_C PF13378.6 AAG05603.1 - 3.5e-55 187.0 0.0 5.1e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 AAG05603.1 - 8.8e-21 74.3 0.0 1.4e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF2437 PF10370.9 AAG05604.1 - 0.034 15.0 2.9 0.11 13.4 1.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2437) Aldedh PF00171.22 AAG05605.1 - 1e-46 159.4 0.1 1.9e-46 158.6 0.1 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_S15 PF02129.18 AAG05606.1 - 1.5e-09 37.9 0.9 2.4e-09 37.2 0.3 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 AAG05606.1 - 6.1e-06 25.9 0.0 4.7e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 AAG05606.1 - 8.6e-06 24.6 0.1 4e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 AAG05606.1 - 2.7e-05 23.9 0.0 0.0005 19.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAG05606.1 - 5.5e-05 22.8 0.1 0.0044 16.5 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family RMMBL PF07521.12 AAG05606.1 - 0.00015 21.6 0.1 0.00043 20.1 0.0 1.7 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain BAAT_C PF08840.11 AAG05606.1 - 0.00058 19.8 0.0 0.00093 19.2 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AAG05606.1 - 0.0011 18.2 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 MFS_1 PF07690.16 AAG05607.1 - 1.5e-30 106.3 90.0 8.9e-26 90.6 55.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG05607.1 - 0.0021 17.0 2.3 0.0021 17.0 2.3 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter LysR_substrate PF03466.20 AAG05608.1 - 3.8e-40 137.5 0.5 1.8e-39 135.3 0.1 1.8 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05608.1 - 7.3e-21 73.9 3.5 1.2e-20 73.2 3.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Cro PF09048.10 AAG05608.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Cro HTH_29 PF13551.6 AAG05609.1 - 3.8e-10 39.6 6.4 1.1e-09 38.1 1.1 2.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 AAG05609.1 - 1.1e-09 38.8 0.3 1.1e-09 38.8 0.3 3.4 4 1 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 AAG05609.1 - 2.9e-08 33.7 2.1 8.7e-08 32.2 2.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG05609.1 - 7e-07 28.9 0.6 1.9e-06 27.5 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 AAG05609.1 - 0.011 16.3 0.6 0.033 14.7 0.6 1.9 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 rve_3 PF13683.6 AAG05609.1 - 0.039 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 AAG05609.1 - 0.093 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DUF3218 PF11508.8 AAG05610.1 - 5.9e-152 503.1 0.0 6.6e-152 502.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3218) Pesticin PF16754.5 AAG05611.1 - 6.7e-18 65.1 0.0 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial toxin homologue of phage lysozyme, C-term MVL PF12151.8 AAG05612.1 - 0.063 13.1 1.3 0.11 12.4 1.3 1.3 1 0 0 1 1 1 0 Mannan-binding protein SLATT_5 PF18160.1 AAG05612.1 - 0.085 12.2 0.2 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HTH_18 PF12833.7 AAG05615.1 - 3.7e-15 55.9 0.5 6.2e-15 55.2 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Arabinose_bd PF12625.7 AAG05615.1 - 4.3e-10 40.0 0.0 1.2e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_AraC PF00165.23 AAG05615.1 - 0.00073 19.6 0.0 0.0024 17.9 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAG05615.1 - 0.027 14.3 0.6 5.2 7.0 0.0 2.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAG05615.1 - 0.13 11.7 0.0 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AAG05615.1 - 0.14 12.0 0.3 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Beta-lactamase PF00144.24 AAG05616.1 - 2.3e-24 86.3 0.1 7.6e-24 84.6 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase MOSC PF03473.17 AAG05617.1 - 1.3e-25 89.9 0.0 1.8e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 AAG05617.1 - 6.6e-13 48.3 3.1 1.2e-12 47.5 3.1 1.5 1 0 0 1 1 1 1 3-alpha domain SLT PF01464.20 AAG05618.1 - 0.069 12.8 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain Bac_transf PF02397.16 AAG05619.1 - 8e-68 227.7 0.0 1.4e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AAG05619.1 - 5.4e-28 98.2 0.5 1.1e-27 97.1 0.5 1.6 1 0 0 1 1 1 1 CoA-binding domain PglD_N PF17836.1 AAG05619.1 - 0.022 15.4 0.0 0.039 14.6 0.0 1.4 1 0 0 1 1 1 0 PglD N-terminal domain MannoseP_isomer PF01050.18 AAG05620.1 - 7.9e-64 214.1 0.1 1.2e-63 213.5 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 AAG05620.1 - 1.9e-59 201.2 0.0 3.1e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Cupin_2 PF07883.11 AAG05620.1 - 2.6e-07 30.3 0.1 5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Cupin domain NTP_transf_3 PF12804.7 AAG05620.1 - 5.2e-06 26.9 6.6 6.9e-06 26.5 1.1 2.8 2 1 0 3 3 3 1 MobA-like NTP transferase domain Glyco_tranf_2_3 PF13641.6 AAG05621.1 - 9.7e-14 51.8 0.0 1.1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AAG05621.1 - 7.7e-12 45.3 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAG05621.1 - 2.5e-05 24.3 0.1 3.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 PALP PF00291.25 AAG05621.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_tranf_2_2 PF10111.9 AAG05621.1 - 0.015 14.8 0.0 3 7.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 WYL PF13280.6 AAG05621.1 - 0.073 13.1 0.2 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 WYL domain Poly_export PF02563.16 AAG05622.1 - 3.2e-14 52.9 0.0 6.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AAG05622.1 - 3.8e-05 23.5 0.2 8e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 SLBB domain GNVR PF13807.6 AAG05623.1 - 6.4e-07 29.2 0.0 1.8e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase Wzz PF02706.15 AAG05623.1 - 0.0051 17.1 0.2 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 Chain length determinant protein V_ATPase_I PF01496.19 AAG05623.1 - 0.079 10.9 1.4 0.13 10.1 1.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.11 AAG05623.1 - 0.2 11.4 7.9 0.057 13.2 2.9 2.4 2 1 0 3 3 3 0 Phage minor structural protein GP20 KLRAQ PF10205.9 AAG05623.1 - 0.56 10.5 10.2 0.47 10.7 2.5 2.9 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein PilO PF04350.13 AAG05623.1 - 4.4 7.5 8.6 2.2 8.4 2.3 2.6 3 0 0 3 3 3 0 Pilus assembly protein, PilO Glycos_transf_1 PF00534.20 AAG05624.1 - 6.6e-15 55.1 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG05624.1 - 1.5e-10 41.6 0.0 2.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAG05624.1 - 0.00023 21.5 0.1 0.0016 18.8 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG05624.1 - 0.0027 17.7 0.2 0.017 15.1 0.0 2.4 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Cellulase PF00150.18 AAG05625.1 - 7.5e-06 25.6 0.0 1.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_39 PF01229.17 AAG05625.1 - 0.00023 19.9 0.1 0.00034 19.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_42 PF02449.15 AAG05625.1 - 0.0023 17.4 0.1 0.018 14.4 0.0 2.0 1 1 1 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 AAG05625.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_trans_4_4 PF13579.6 AAG05626.1 - 5.7e-25 88.6 19.3 9e-25 88.0 10.5 2.3 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AAG05626.1 - 1.2e-20 74.3 0.0 2.7e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG05626.1 - 1.4e-18 67.4 1.5 3e-18 66.4 0.7 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAG05626.1 - 9.6e-12 45.1 0.0 3.6e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAG05626.1 - 2.8e-07 30.2 0.0 3.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG05627.1 - 1.6e-10 41.5 0.0 3.2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAG05627.1 - 2e-10 40.5 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG05627.1 - 7e-10 39.2 0.2 1.6e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAG05627.1 - 5.3e-08 33.5 2.9 5.3e-08 33.5 2.9 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Wzy_C PF04932.15 AAG05628.1 - 0.0003 20.4 4.2 0.0003 20.4 4.2 4.8 3 2 1 4 4 4 1 O-Antigen ligase MurJ PF03023.14 AAG05629.1 - 1.1e-41 142.9 15.9 1.5e-41 142.5 15.9 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_3 PF13440.6 AAG05629.1 - 7.7e-06 25.3 0.5 1.7e-05 24.2 0.5 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein MatE PF01554.18 AAG05629.1 - 2.4e-05 24.1 13.4 0.021 14.5 2.1 2.8 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 AAG05629.1 - 0.00013 22.0 16.1 0.00013 22.0 16.1 4.4 4 3 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Acyl_transf_3 PF01757.22 AAG05630.1 - 4.1e-26 91.8 35.6 4.8e-26 91.6 35.6 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF5455 PF17537.2 AAG05630.1 - 0.41 11.1 8.8 0.19 12.1 1.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5455) FAD_binding_2 PF00890.24 AAG05631.1 - 7.6e-116 387.6 1.2 8.6e-116 387.4 1.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAG05631.1 - 1.9e-17 63.9 1.2 3.3e-17 63.1 1.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAG05631.1 - 2.5e-11 43.6 0.2 3.6e-11 43.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG05631.1 - 5e-07 29.9 0.9 2e-06 27.9 0.9 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG05631.1 - 2.2e-06 27.1 0.1 8.7e-05 21.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG05631.1 - 4e-06 25.8 0.3 4e-06 25.8 0.3 2.5 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 AAG05631.1 - 1.1e-05 24.8 1.2 0.00011 21.5 0.7 2.4 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 AAG05631.1 - 0.00048 19.5 0.3 0.0007 18.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAG05631.1 - 0.0014 17.8 1.2 0.011 14.9 2.6 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAG05631.1 - 0.024 13.9 0.6 0.036 13.4 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AAG05631.1 - 0.031 13.5 0.1 0.048 12.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG05631.1 - 0.15 12.6 0.6 0.62 10.7 0.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HTH_35 PF13693.6 AAG05631.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MCRA PF06100.11 AAG05631.1 - 0.25 10.1 0.2 0.35 9.6 0.2 1.1 1 0 0 1 1 1 0 MCRA family Amino_oxidase PF01593.24 AAG05631.1 - 0.26 10.5 2.1 2.1 7.5 0.2 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 AAG05631.1 - 0.52 9.3 6.9 0.072 12.1 2.5 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Topoisom_I PF01028.20 AAG05632.1 - 3.1e-28 98.6 0.0 3.9e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core AsnC_trans_reg PF01037.21 AAG05634.1 - 8.6e-23 80.1 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAG05634.1 - 1.2e-18 66.4 0.4 1.7e-18 65.9 0.4 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAG05634.1 - 9.1e-16 57.4 5.0 1.3e-15 56.9 5.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 AAG05634.1 - 0.00057 19.6 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 AAG05634.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAG05634.1 - 0.016 15.7 0.1 0.026 15.0 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_20 PF12840.7 AAG05634.1 - 0.026 14.6 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 AAG05634.1 - 0.043 13.7 0.2 0.077 12.9 0.2 1.4 1 0 0 1 1 1 0 MarR family Sun2_CC2 PF18580.1 AAG05634.1 - 0.076 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 E1_dh PF00676.20 AAG05635.1 - 9.9e-100 333.3 0.0 1.2e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoDH_E1alpha_N PF12573.8 AAG05635.1 - 6.7e-21 73.8 2.1 1.1e-20 73.1 2.1 1.4 1 0 0 1 1 1 1 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal TPP_enzyme_C PF02775.21 AAG05635.1 - 0.014 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3390 PF11870.8 AAG05635.1 - 0.049 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Transket_pyr PF02779.24 AAG05636.1 - 6.1e-44 149.8 0.0 8.8e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAG05636.1 - 1.4e-35 121.9 0.0 2.6e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain 2-oxoacid_dh PF00198.23 AAG05637.1 - 8.1e-79 264.3 0.0 1e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAG05637.1 - 4.3e-19 68.1 1.8 7.1e-19 67.4 1.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 AAG05637.1 - 7.9e-12 45.3 0.0 2.2e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AAG05637.1 - 0.018 14.9 1.5 0.29 11.0 0.2 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.6 AAG05637.1 - 0.025 14.5 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 AAG05637.1 - 0.078 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.6 AAG05637.1 - 0.11 13.2 1.4 10 6.9 0.2 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Pyr_redox_2 PF07992.14 AAG05638.1 - 5.2e-68 229.4 1.0 6.7e-68 229.1 1.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAG05638.1 - 3.6e-30 104.5 0.1 6.8e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAG05638.1 - 1.1e-17 64.4 3.7 3.4e-17 62.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG05638.1 - 6.4e-07 28.8 7.2 2e-05 23.9 3.6 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAG05638.1 - 4.6e-05 23.0 1.9 4.6e-05 23.0 1.9 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAG05638.1 - 0.00046 19.6 7.4 0.42 9.8 0.4 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG05638.1 - 0.00053 20.2 9.9 0.027 14.7 0.2 3.2 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAG05638.1 - 0.00064 18.5 5.7 0.33 9.6 1.3 4.0 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.24 AAG05638.1 - 0.0079 15.3 13.5 0.065 12.3 3.6 3.5 3 1 1 4 4 4 2 FAD binding domain DAO PF01266.24 AAG05638.1 - 0.0086 15.7 23.6 0.36 10.4 0.1 4.3 2 2 2 4 4 4 3 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG05638.1 - 0.019 14.5 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 AAG05638.1 - 0.028 13.7 11.0 0.38 10.0 2.5 2.7 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 AAG05638.1 - 0.31 10.3 3.5 1 8.6 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HTH_26 PF13443.6 AAG05639.1 - 0.053 14.0 0.0 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Na_Ala_symp PF01235.17 AAG05640.1 - 6.5e-146 486.6 22.4 7.8e-146 486.4 22.4 1.0 1 0 0 1 1 1 1 Sodium:alanine symporter family Asparaginase PF00710.20 AAG05641.1 - 2.7e-46 157.6 0.0 3.5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AAG05641.1 - 2.2e-23 82.7 0.0 5.5e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain DIT1_PvcA PF05141.12 AAG05642.1 - 4.7e-78 262.4 0.0 5.9e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 AAG05643.1 - 5.8e-39 134.5 2.2 7.1e-39 134.2 2.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 AAG05643.1 - 0.035 13.2 0.0 0.092 11.8 0.0 1.6 2 0 0 2 2 2 0 CsiD HpaB_N PF11794.8 AAG05644.1 - 7.8e-89 298.0 0.0 1e-88 297.6 0.0 1.1 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 AAG05644.1 - 7.1e-55 185.2 0.1 1.2e-54 184.5 0.1 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Cytochrome_CBB3 PF13442.6 AAG05645.1 - 2.7e-15 56.4 0.3 3.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG05645.1 - 2.4e-14 54.2 0.7 6e-06 27.3 0.0 3.1 2 2 0 2 2 2 2 Cytochrome c Paired_CXXCH_1 PF09699.10 AAG05645.1 - 0.0014 18.4 0.1 0.62 9.9 0.0 2.3 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) CCP_MauG PF03150.14 AAG05645.1 - 0.012 16.3 0.0 0.63 10.7 0.0 2.1 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Cytochrome_C7 PF14522.6 AAG05645.1 - 0.04 13.9 0.0 8.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF1924 PF09086.11 AAG05645.1 - 0.05 14.0 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Cytochrom_C550 PF14495.6 AAG05645.1 - 0.094 12.4 0.0 3.8 7.2 0.0 2.6 3 0 0 3 3 3 0 Cytochrome c-550 domain PSCyt1 PF07635.11 AAG05645.1 - 0.45 11.2 3.1 3.3 8.4 0.0 2.7 2 1 0 2 2 2 0 Planctomycete cytochrome C LysR_substrate PF03466.20 AAG05646.1 - 3.5e-50 170.3 4.2 3.5e-50 170.3 4.2 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05646.1 - 5e-21 74.4 2.3 5e-21 74.4 2.3 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAG05646.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAG05646.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 AAG05646.1 - 0.048 13.5 0.6 0.11 12.3 0.6 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAG05646.1 - 0.091 12.9 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_50 PF18024.1 AAG05646.1 - 0.13 11.9 0.4 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Peripla_BP_3 PF13377.6 AAG05647.1 - 3e-22 79.7 0.3 2.1e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAG05647.1 - 6.7e-22 78.2 0.0 1.1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AAG05647.1 - 1.3e-13 50.5 0.2 1.2e-12 47.4 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 AAG05647.1 - 0.00019 21.7 0.5 0.00086 19.6 0.5 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 AAG05647.1 - 0.0005 19.8 0.1 0.0021 17.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_3 PF01381.22 AAG05647.1 - 0.0048 16.9 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_IclR PF09339.10 AAG05647.1 - 0.0053 16.5 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain Peripla_BP_4 PF13407.6 AAG05647.1 - 0.0088 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain MarR_2 PF12802.7 AAG05647.1 - 0.054 13.4 0.3 0.33 10.9 0.0 2.5 3 0 0 3 3 3 0 MarR family HTH_24 PF13412.6 AAG05647.1 - 0.068 12.7 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 AAG05647.1 - 0.13 12.3 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family AP_endonuc_2 PF01261.24 AAG05648.1 - 2.6e-07 30.3 0.0 5.9e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel PfkB PF00294.24 AAG05649.1 - 6.3e-59 199.7 0.0 7e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MFS_1 PF07690.16 AAG05650.1 - 3.9e-68 229.9 61.5 3.7e-56 190.6 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG05650.1 - 1e-05 25.0 23.1 0.00098 18.5 23.1 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB 2-Hacid_dh_C PF02826.19 AAG05651.1 - 7.2e-63 211.2 0.0 9.2e-63 210.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAG05651.1 - 6.4e-28 97.1 0.0 7.4e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAG05651.1 - 2.7e-05 24.4 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 AAG05651.1 - 0.017 15.0 0.1 0.038 13.8 0.1 1.6 1 0 0 1 1 1 0 Rossmann-like domain F420_oxidored PF03807.17 AAG05651.1 - 0.063 13.9 0.0 0.18 12.4 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gluconate_2-dh3 PF13618.6 AAG05652.1 - 7.5e-37 126.6 0.0 1.2e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 GMC_oxred_C PF05199.13 AAG05653.1 - 7.5e-27 94.6 0.0 1.7e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 AAG05653.1 - 3.9e-10 39.6 0.0 8.7e-09 35.2 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.19 AAG05653.1 - 0.0086 15.4 0.0 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAG05653.1 - 0.084 12.1 0.0 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cytochrom_C PF00034.21 AAG05654.1 - 2e-25 89.7 0.0 1.2e-09 39.1 0.0 3.5 3 1 0 3 3 3 3 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG05654.1 - 9.6e-22 77.1 0.7 9.2e-11 41.9 0.0 3.8 3 1 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 AAG05654.1 - 1.1e-05 25.0 1.4 2.1 8.1 0.1 3.3 3 0 0 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) DHOR PF06537.11 AAG05654.1 - 0.018 13.7 0.1 0.77 8.3 0.0 3.0 4 0 0 4 4 4 0 Di-haem oxidoreductase, putative peroxidase Cytochrom_C550 PF14495.6 AAG05654.1 - 0.097 12.4 0.1 2.7 7.7 0.0 2.8 1 1 1 2 2 2 0 Cytochrome c-550 domain PSCyt1 PF07635.11 AAG05654.1 - 0.14 12.7 1.2 14 6.3 0.0 4.1 3 1 1 4 4 4 0 Planctomycete cytochrome C LysR_substrate PF03466.20 AAG05655.1 - 2.1e-28 99.1 7.1 3.3e-28 98.5 7.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05655.1 - 1.4e-10 41.0 1.0 2.9e-10 39.9 1.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_29 PF13551.6 AAG05655.1 - 1.3e-05 25.1 0.5 3.1e-05 23.9 0.5 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AAG05655.1 - 0.00011 22.3 0.1 0.00032 20.7 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG05655.1 - 0.00056 19.6 0.1 0.0017 18.1 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAG05655.1 - 0.0016 17.8 0.2 0.0041 16.5 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DUF3458_C PF17432.2 AAG05655.1 - 0.02 14.3 1.1 0.026 13.9 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats HTH_30 PF13556.6 AAG05655.1 - 0.066 13.0 0.6 0.19 11.5 0.1 2.1 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain MarR PF01047.22 AAG05655.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 AAG05655.1 - 0.27 11.0 1.2 0.91 9.3 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain GATase PF00117.28 AAG05656.1 - 5.1e-10 39.4 0.0 7.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ABM PF03992.16 AAG05656.1 - 2.4e-07 30.8 0.2 5.1e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Peptidase_C26 PF07722.13 AAG05656.1 - 3.3e-06 27.0 0.0 5.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 DUF4188 PF13826.6 AAG05656.1 - 0.0012 19.2 0.1 0.0019 18.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) MFS_1 PF07690.16 AAG05657.1 - 1.4e-17 63.7 56.8 1.4e-08 34.1 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TetR_N PF00440.23 AAG05658.1 - 7.6e-17 60.8 0.9 1.9e-16 59.6 0.9 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Acetyltransf_10 PF13673.7 AAG05659.1 - 1.3e-12 47.8 0.0 1.7e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG05659.1 - 2.8e-12 46.9 0.0 3.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG05659.1 - 1.1e-11 44.9 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG05659.1 - 0.00018 21.7 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG05659.1 - 0.0017 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAG05659.1 - 0.014 15.5 0.0 0.096 12.8 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAG05659.1 - 0.021 15.0 2.9 0.037 14.2 2.9 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG05659.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Transpeptidase PF00905.22 AAG05660.1 - 4.8e-81 272.3 0.0 6e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AAG05660.1 - 1.1e-13 51.9 0.0 4.4e-12 46.7 0.0 2.2 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MerR-DNA-bind PF09278.11 AAG05661.1 - 5.6e-16 58.8 0.8 8.6e-16 58.2 0.8 1.3 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 AAG05661.1 - 2.3e-15 56.4 0.0 3.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAG05661.1 - 6e-13 48.3 0.0 2.3e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 MerR family regulatory protein HTH_IclR PF09339.10 AAG05661.1 - 0.00021 21.0 0.1 0.31 10.9 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_31 PF13560.6 AAG05661.1 - 0.0022 18.3 4.7 0.094 13.1 0.6 2.5 1 1 1 2 2 2 2 Helix-turn-helix domain TetR_N PF00440.23 AAG05661.1 - 0.018 14.8 0.8 0.05 13.4 0.1 2.0 2 1 0 2 2 2 0 Bacterial regulatory proteins, tetR family MarR PF01047.22 AAG05661.1 - 0.018 15.0 0.0 1.7 8.6 0.0 3.1 2 1 0 2 2 2 0 MarR family HipA_C PF07804.12 AAG05661.1 - 0.047 13.4 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 HipA-like C-terminal domain DNA_meth_N PF18284.1 AAG05661.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 DNA methylase N-terminal domain HTH_3 PF01381.22 AAG05661.1 - 0.13 12.3 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix ABM PF03992.16 AAG05662.1 - 6.9e-06 26.1 0.1 9.6e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ADH_N PF08240.12 AAG05663.1 - 1.4e-26 92.5 0.8 2.4e-26 91.7 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAG05663.1 - 8.3e-21 74.3 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAG05663.1 - 3.5e-06 28.1 0.0 6.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAG05663.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AAG05663.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAG05663.1 - 0.0089 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 AAG05663.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AraC_N PF06719.13 AAG05664.1 - 1e-43 148.5 0.0 1.4e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 AAG05664.1 - 8.9e-20 70.8 1.6 1.2e-19 70.3 0.3 2.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05664.1 - 1.9e-15 56.5 0.7 8.1e-09 35.4 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 AAG05664.1 - 0.054 13.3 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_5 PF01022.20 AAG05665.1 - 2.6e-13 49.6 0.6 3.8e-13 49.1 0.6 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAG05665.1 - 5.5e-07 29.5 0.6 9e-07 28.9 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain ArsB PF02040.15 AAG05666.1 - 2e-149 498.5 25.4 2.4e-149 498.3 25.4 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 AAG05666.1 - 5.1e-27 94.9 40.9 5.1e-27 94.9 40.9 1.7 1 1 1 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 AAG05666.1 - 0.0058 15.7 30.6 0.11 11.5 5.1 2.4 1 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region LMWPc PF01451.21 AAG05667.1 - 6.6e-30 104.4 0.0 7.8e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Gluconate_2-dh3 PF13618.6 AAG05667.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 FMN_red PF03358.15 AAG05668.1 - 6e-27 94.3 0.0 8.1e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase HTH_18 PF12833.7 AAG05669.1 - 1.1e-19 70.5 0.2 1.1e-19 70.5 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05669.1 - 9.1e-12 44.8 0.0 0.00016 21.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family CENP-B_N PF04218.13 AAG05669.1 - 0.0015 18.2 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 AAG05669.1 - 0.0032 16.8 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 AAG05669.1 - 0.011 15.7 0.1 3.7 7.7 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn helix HTH_23 PF13384.6 AAG05669.1 - 0.058 13.2 0.1 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Peptidase_M48 PF01435.18 AAG05671.1 - 9.7e-12 45.1 0.9 2.5e-11 43.7 0.9 1.6 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AAG05671.1 - 0.0096 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M48 PF01435.18 AAG05674.1 - 4.1e-13 49.6 1.2 7.7e-13 48.7 0.2 2.0 2 0 0 2 2 2 1 Peptidase family M48 SURF1 PF02104.15 AAG05674.1 - 0.013 15.8 0.4 0.025 14.8 0.4 1.5 1 0 0 1 1 1 0 SURF1 family PAP_PilO PF06864.12 AAG05674.1 - 0.028 13.3 0.2 0.055 12.3 0.2 1.4 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Tetraspanin PF00335.20 AAG05674.1 - 0.35 10.6 1.7 0.61 9.8 1.7 1.4 1 0 0 1 1 1 0 Tetraspanin family GspL_C PF12693.7 AAG05674.1 - 5.1 6.9 9.4 0.13 12.1 2.7 1.8 2 0 0 2 2 2 0 GspL periplasmic domain UcrQ PF02939.16 AAG05675.1 - 0.0045 16.9 0.0 0.71 9.9 0.0 2.5 3 0 0 3 3 3 2 UcrQ family Phage_holin_3_6 PF07332.11 AAG05675.1 - 0.21 11.6 3.8 0.34 11.0 3.8 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TonB_dep_Rec PF00593.24 AAG05677.1 - 4.9e-47 161.9 18.2 7.1e-47 161.4 18.2 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG05677.1 - 3.8e-18 66.0 0.8 8.9e-18 64.8 0.8 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG05677.1 - 8.4e-08 31.6 0.0 2.4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family PQQ PF01011.21 AAG05678.1 - 7.3e-36 120.4 2.8 8.6e-06 25.4 0.0 7.7 7 0 0 7 7 7 7 PQQ enzyme repeat PQQ_2 PF13360.6 AAG05678.1 - 9.6e-19 67.9 1.5 2.8e-09 36.9 0.0 4.7 2 1 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AAG05678.1 - 3.1e-10 40.2 18.7 1.8 9.2 0.0 7.8 9 0 0 9 9 9 5 PQQ-like domain OprB PF04966.12 AAG05679.1 - 3.5e-119 398.6 8.7 4e-119 398.4 8.7 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family DUF971 PF06155.12 AAG05680.1 - 5.3e-22 78.2 0.0 6.1e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF971) HEAT_2 PF13646.6 AAG05681.1 - 9.2e-67 221.5 83.2 1.2e-14 54.5 6.8 4.9 1 1 5 6 6 6 6 HEAT repeats HEAT PF02985.22 AAG05681.1 - 3.6e-28 95.2 27.7 0.00018 21.5 0.1 10.2 10 0 0 10 10 10 8 HEAT repeat HEAT_PBS PF03130.16 AAG05681.1 - 3e-17 61.5 79.0 0.00017 21.9 0.2 10.7 10 1 1 11 11 11 8 PBS lyase HEAT-like repeat Cnd1 PF12717.7 AAG05681.1 - 2.4e-11 44.0 0.2 2.7 8.0 0.0 6.6 3 3 1 6 6 6 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 AAG05681.1 - 9.9e-09 35.5 48.7 0.0063 17.0 1.0 9.3 6 4 4 10 10 10 6 HEAT-like repeat Arm PF00514.23 AAG05681.1 - 9.2e-06 25.5 20.5 0.34 11.0 0.1 7.2 8 1 0 8 8 8 3 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 AAG05681.1 - 0.012 15.2 2.0 2.8 7.5 0.0 4.6 4 2 1 5 5 5 0 CLASP N terminal DUF1641 PF07849.11 AAG05681.1 - 0.021 14.7 4.3 4.7 7.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1641) TAF6_C PF07571.13 AAG05681.1 - 0.2 12.0 1.1 8.6 6.8 0.0 3.0 2 1 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain DUF2019 PF09450.10 AAG05681.1 - 0.96 9.4 6.4 0.58 10.1 0.4 3.2 2 2 3 5 5 5 0 Domain of unknown function (DUF2019) ABC_tran PF00005.27 AAG05682.1 - 2.1e-31 109.3 0.0 2.8e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAG05682.1 - 1.1e-05 25.9 0.0 1.7e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG05682.1 - 0.0002 21.3 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 AAG05682.1 - 0.00023 21.4 0.0 0.0055 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAG05682.1 - 0.00049 19.8 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AAG05682.1 - 0.00065 20.1 0.0 0.0018 18.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 AAG05682.1 - 0.0007 19.5 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 AAG05682.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 AAG05682.1 - 0.0096 15.9 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAG05682.1 - 0.012 15.5 0.2 0.063 13.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 AAG05682.1 - 0.022 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAG05682.1 - 0.027 14.9 0.0 0.041 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAG05682.1 - 0.029 14.9 0.0 0.044 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG05682.1 - 0.036 14.3 0.1 0.069 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG05682.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 AAG05682.1 - 0.05 14.0 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase SMC_N PF02463.19 AAG05682.1 - 0.073 12.5 0.0 0.99 8.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AAG05682.1 - 0.082 13.0 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AAG05682.1 - 0.083 13.1 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAG05682.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAG05682.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein BPD_transp_1 PF00528.22 AAG05683.1 - 5.6e-18 65.3 12.0 5.6e-18 65.3 12.0 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component NMT1_2 PF13379.6 AAG05684.1 - 9.9e-15 54.9 0.0 1.5e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAG05684.1 - 1.6e-06 28.2 0.0 4.5e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAG05684.1 - 0.00016 21.4 0.1 0.00031 20.4 0.1 1.5 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NosL PF05573.12 AAG05684.1 - 0.004 17.5 0.1 0.015 15.6 0.1 1.9 1 1 0 1 1 1 1 NosL VitK2_biosynth PF02621.14 AAG05684.1 - 0.0084 15.7 0.0 0.069 12.7 0.0 2.2 1 1 0 2 2 2 1 Menaquinone biosynthesis SBP_bac_3 PF00497.20 AAG05684.1 - 0.02 14.3 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 AAG05684.1 - 0.11 12.0 0.2 0.64 9.5 0.0 2.2 2 1 1 3 3 3 0 Substrate binding domain of ABC-type glycine betaine transport system Fer4_7 PF12838.7 AAG05685.1 - 5.8e-10 39.6 23.7 8.7e-08 32.6 13.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG05685.1 - 1.4e-08 34.8 9.1 2e-08 34.3 9.1 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG05685.1 - 4.4e-08 32.9 15.2 2.6e-06 27.2 3.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 AAG05685.1 - 2.8e-07 30.1 19.2 0.00085 19.0 2.8 3.2 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAG05685.1 - 1.1e-06 28.7 23.1 5.7e-05 23.2 11.5 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG05685.1 - 2.2e-05 24.5 12.9 0.00013 22.0 13.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG05685.1 - 6e-05 23.9 8.5 0.021 15.8 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AAG05685.1 - 0.00037 20.4 13.1 0.00044 20.2 3.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 AAG05685.1 - 0.019 15.4 1.6 0.019 15.4 1.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AAG05685.1 - 0.036 14.6 12.6 0.34 11.5 2.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAG05685.1 - 0.14 13.1 15.9 0.66 11.1 4.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AAG05685.1 - 0.9 10.0 14.2 0.46 11.0 2.9 2.2 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAG05685.1 - 1.1 9.8 15.2 75 4.0 15.2 2.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AAG05685.1 - 1.4 9.2 10.7 5 7.4 3.6 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain FAD_binding_2 PF00890.24 AAG05686.1 - 5.1e-37 128.0 2.9 7.1e-37 127.5 2.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAG05686.1 - 1.9e-13 50.5 0.2 4.7e-13 49.2 0.1 1.7 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AAG05686.1 - 2e-08 33.8 0.5 0.00048 19.5 0.3 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG05686.1 - 4.4e-06 25.6 0.1 1e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 AAG05686.1 - 4.7e-05 22.9 2.2 0.00012 21.5 0.5 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 AAG05686.1 - 0.00017 21.3 0.6 0.0011 18.7 0.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 AAG05686.1 - 0.0005 19.0 0.1 0.00091 18.2 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 AAG05686.1 - 0.00099 18.3 4.8 0.042 12.9 0.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 AAG05686.1 - 0.01 15.1 0.1 0.033 13.4 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 AAG05686.1 - 0.068 12.2 0.8 0.12 11.4 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAG05686.1 - 0.086 13.1 0.1 0.28 11.5 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AAG05686.1 - 0.17 11.2 0.3 0.34 10.2 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UTRA PF07702.13 AAG05687.1 - 6.7e-37 126.5 0.2 8.6e-37 126.1 0.2 1.1 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAG05687.1 - 5.4e-20 70.8 0.0 1.6e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 AAG05687.1 - 0.00019 21.1 0.0 0.00047 19.8 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAG05687.1 - 0.00071 19.5 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AAG05687.1 - 0.0049 16.8 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAG05687.1 - 0.052 13.1 0.2 0.27 10.8 0.0 2.2 2 1 1 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 AAG05687.1 - 0.072 13.6 0.1 29 5.2 0.0 3.6 4 0 0 4 4 4 0 Winged helix DNA-binding domain Sigma70_r3 PF04539.16 AAG05687.1 - 0.073 13.2 0.1 8.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-70 region 3 Fe_dep_repress PF01325.19 AAG05687.1 - 0.075 13.2 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 AAG05687.1 - 0.078 13.3 0.0 0.2 12.0 0.0 1.6 2 0 0 2 2 1 0 Transcriptional regulator TrmB PF01978.19 AAG05687.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Crp PF00325.20 AAG05687.1 - 0.12 12.0 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Glyco_hydro_18 PF00704.28 AAG05688.1 - 8.2e-28 98.0 0.4 2.7e-27 96.3 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 fn3 PF00041.21 AAG05688.1 - 8.4e-06 26.0 0.1 4.2e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 Fibronectin type III domain fn3_2 PF16893.5 AAG05688.1 - 0.023 14.8 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain MoeA_C PF03454.15 AAG05688.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) tRNA_edit PF04073.15 AAG05689.1 - 5.1e-21 75.0 0.1 6.6e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain AMP-binding PF00501.28 AAG05690.1 - 1.7e-78 264.1 0.0 2.4e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AAG05690.1 - 2.8e-55 187.8 0.0 1.1e-52 179.3 0.0 2.2 2 0 0 2 2 2 2 Condensation domain Thioesterase PF00975.20 AAG05690.1 - 4.8e-33 115.2 0.0 8.5e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 AAG05690.1 - 7.2e-22 77.5 0.1 2.1e-13 50.4 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_21 PF05050.12 AAG05690.1 - 1.2e-13 51.4 0.0 2.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain AMP-binding_C PF13193.6 AAG05690.1 - 3.7e-10 40.6 0.6 0.0026 18.7 0.0 3.5 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain V_cholerae_RfbT PF05575.11 AAG05690.1 - 0.005 16.2 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Abhydrolase_1 PF00561.20 AAG05690.1 - 0.058 13.0 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold TauD PF02668.16 AAG05691.1 - 1.5e-49 169.2 1.3 1.9e-49 168.9 1.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HAD_SAK_2 PF18143.1 AAG05691.1 - 0.0016 18.8 0.1 0.003 17.9 0.1 1.4 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins DUF2334 PF10096.9 AAG05691.1 - 0.02 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) TauD PF02668.16 AAG05692.1 - 1.1e-49 169.6 0.8 1.6e-49 169.1 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AMP-binding PF00501.28 AAG05693.1 - 8.7e-88 294.7 0.0 1.8e-87 293.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AAG05693.1 - 8.5e-34 117.0 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 AAG05693.1 - 2e-09 38.3 0.0 7.1e-09 36.5 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AAG05693.1 - 1.2e-06 28.8 0.0 3.6e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site LysE PF01810.18 AAG05694.1 - 1.5e-17 63.7 9.7 2.1e-17 63.2 9.7 1.2 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAG05694.1 - 0.028 14.1 4.6 1.3 8.7 4.6 2.6 1 1 1 2 2 2 0 Integral membrane protein TerC family DUF3392 PF11872.8 AAG05694.1 - 0.044 14.0 1.2 0.044 14.0 1.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) BPD_transp_1 PF00528.22 AAG05695.1 - 1.6e-12 47.5 19.2 1.3e-11 44.6 16.5 2.0 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAG05696.1 - 8.2e-32 110.6 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG05696.1 - 1.1e-07 31.9 0.1 0.0064 16.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AAG05696.1 - 8.9e-06 26.2 0.5 0.00014 22.3 0.5 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAG05696.1 - 1.2e-05 25.0 0.0 2.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG05696.1 - 8.8e-05 22.8 0.0 0.0002 21.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAG05696.1 - 0.0002 21.6 0.1 0.0029 17.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAG05696.1 - 0.00026 20.5 0.0 0.41 10.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG05696.1 - 0.00029 21.3 0.0 0.00046 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG05696.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase DUF815 PF05673.13 AAG05696.1 - 0.0083 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 AAG05696.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_ATPase PF09818.9 AAG05696.1 - 0.014 14.2 0.0 0.37 9.6 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 AAG05696.1 - 0.018 15.0 0.5 0.058 13.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 AAG05696.1 - 0.025 15.1 0.0 0.037 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAG05696.1 - 0.028 14.3 0.1 0.17 11.8 0.0 2.3 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 AAG05696.1 - 0.058 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 AAG05696.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 AAG05696.1 - 0.097 12.0 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.9 AAG05696.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_33 PF13671.6 AAG05696.1 - 0.12 12.5 1.4 0.31 11.2 0.4 2.3 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 AAG05696.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 AAG05696.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.4 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 AAG05696.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 AAG05696.1 - 0.2 11.9 0.4 1 9.6 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NMT1_2 PF13379.6 AAG05697.1 - 5.7e-24 85.2 0.1 7.8e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 NMT1-like family Lipoprotein_9 PF03180.14 AAG05697.1 - 3.6e-05 23.0 0.0 0.005 16.0 0.0 2.1 2 0 0 2 2 2 2 NLPA lipoprotein NMT1 PF09084.11 AAG05697.1 - 4.8e-05 23.4 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like dDENN PF03455.19 AAG05697.1 - 0.03 14.3 0.2 0.06 13.4 0.2 1.5 1 0 0 1 1 1 0 dDENN domain OpuAC PF04069.12 AAG05697.1 - 0.057 13.0 1.5 0.56 9.7 1.5 2.1 1 1 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Phage_TAC_10 PF10963.8 AAG05697.1 - 0.17 12.1 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone TauD PF02668.16 AAG05698.1 - 4.2e-66 223.5 1.0 4.9e-66 223.3 1.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_9 PF10081.9 AAG05698.1 - 0.018 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family HTH_3 PF01381.22 AAG05700.1 - 1.8e-12 47.1 0.1 2.8e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Cupin_2 PF07883.11 AAG05700.1 - 6.4e-11 41.8 0.0 1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain HTH_31 PF13560.6 AAG05700.1 - 2.8e-10 40.4 0.2 2.8e-10 40.4 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG05700.1 - 5.8e-10 39.0 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AAG05700.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_26 PF13443.6 AAG05700.1 - 0.0011 19.3 0.1 0.0021 18.5 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain CENP-C_C PF11699.8 AAG05700.1 - 0.0027 17.9 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 Mif2/CENP-C like HTH_25 PF13413.6 AAG05700.1 - 0.0098 15.7 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 AAG05700.1 - 0.02 14.7 0.1 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family MFS_1 PF07690.16 AAG05702.1 - 2.1e-37 128.9 90.2 2.2e-33 115.6 52.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG05702.1 - 2.9e-07 29.7 7.7 2.9e-07 29.7 7.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAG05702.1 - 4.5e-07 29.1 4.9 4.5e-07 29.1 4.9 2.2 1 1 1 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 AAG05702.1 - 0.0054 16.1 40.7 0.0088 15.4 40.7 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB FeoB_C PF07664.12 AAG05702.1 - 0.78 9.5 5.6 2 8.2 0.0 4.2 4 1 0 4 4 4 0 Ferrous iron transport protein B C terminus Beta-lactamase PF00144.24 AAG05703.1 - 6.2e-72 242.6 1.0 7.6e-72 242.3 1.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 AAG05703.1 - 0.063 12.9 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase enzyme family LysR_substrate PF03466.20 AAG05704.1 - 1.8e-45 154.9 2.9 2.4e-45 154.5 2.9 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05704.1 - 1.2e-18 66.8 1.8 2.6e-18 65.7 1.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 AAG05704.1 - 7.3e-05 22.5 0.7 0.011 15.5 0.6 2.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_30 PF13556.6 AAG05704.1 - 0.004 16.9 0.1 0.01 15.6 0.1 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AAG05704.1 - 0.013 15.0 0.3 0.3 10.7 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DAO PF01266.24 AAG05705.1 - 4.4e-38 131.8 0.3 5.1e-38 131.6 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG05705.1 - 4.5e-06 26.1 0.3 7e-06 25.4 0.3 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 AAG05705.1 - 0.00012 21.3 0.9 0.00018 20.8 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAG05705.1 - 0.00012 21.4 0.2 0.00017 20.9 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG05705.1 - 0.00014 21.2 0.1 0.0029 16.9 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG05705.1 - 0.0016 18.6 1.9 0.0016 18.6 1.9 2.3 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAG05705.1 - 0.0022 17.3 0.7 0.0032 16.8 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAG05705.1 - 0.0026 17.2 1.5 0.0037 16.7 1.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAG05705.1 - 0.0073 16.8 1.0 0.034 14.7 1.6 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG05705.1 - 0.048 12.7 1.2 0.068 12.3 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 AAG05705.1 - 0.23 10.1 0.5 0.39 9.3 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 AAG05705.1 - 0.24 11.4 1.1 0.43 10.6 1.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 AAG05705.1 - 0.31 9.8 1.6 0.54 9.1 1.6 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Cupin_3 PF05899.12 AAG05706.1 - 1.3e-17 63.3 1.4 2.9e-17 62.1 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AAG05706.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Transposase_20 PF02371.16 AAG05707.1 - 7.2e-25 87.1 0.7 1.9e-24 85.8 0.7 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAG05707.1 - 5.4e-15 55.6 0.2 2.4e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 Transposase Cep57_MT_bd PF06657.13 AAG05707.1 - 0.0024 18.3 0.5 0.0056 17.1 0.1 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 HHH PF00633.23 AAG05707.1 - 0.02 14.7 0.1 0.063 13.2 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lzipper-MIP1 PF14389.6 AAG05707.1 - 0.021 15.1 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_transf_4 PF13439.6 AAG05707.1 - 0.054 13.5 0.4 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HalX PF08663.10 AAG05707.1 - 0.095 13.0 1.6 0.33 11.3 1.6 1.9 1 0 0 1 1 1 0 HalX domain DUF3287 PF11690.8 AAG05707.1 - 0.11 12.2 0.6 0.31 10.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ABC_tran_CTD PF16326.5 AAG05707.1 - 0.12 12.6 1.5 0.25 11.6 1.5 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AAG05707.1 - 0.4 10.8 3.0 0.23 11.5 0.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation Peripla_BP_3 PF13377.6 AAG05708.1 - 4.6e-30 105.1 0.5 2.3e-29 102.9 0.1 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAG05708.1 - 5e-19 68.8 0.0 6.8e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AAG05708.1 - 1.3e-13 50.5 0.6 2.5e-13 49.6 0.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AAG05708.1 - 3.2e-13 49.8 0.0 2.8e-12 46.8 0.0 2.3 2 1 0 2 2 2 1 Periplasmic binding protein domain HTH_3 PF01381.22 AAG05708.1 - 0.09 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix AAA_33 PF13671.6 AAG05709.1 - 1.9e-10 41.1 0.0 2.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 AAG05709.1 - 3.2e-06 27.3 0.0 3.9e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 AAG05709.1 - 0.00014 22.4 0.0 0.00055 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AAG05709.1 - 0.00027 20.7 0.0 0.00035 20.4 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 AAG05709.1 - 0.0011 19.4 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 AAG05709.1 - 0.013 15.4 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 AAG05709.1 - 0.036 13.8 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 AAG05709.1 - 0.062 13.8 0.0 0.069 13.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter dNK PF01712.19 AAG05709.1 - 0.13 12.1 0.0 6.6 6.5 0.0 2.1 1 1 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activ_2 PF14532.6 AAG05709.1 - 0.13 12.3 0.1 0.56 10.3 0.1 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA PF00004.29 AAG05709.1 - 0.17 12.3 0.0 0.26 11.7 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AAG05709.1 - 0.2 11.9 0.4 1.4 9.1 0.2 2.2 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAG05709.1 - 0.24 11.8 0.0 0.34 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 AAG05709.1 - 0.26 11.0 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GntP_permease PF02447.16 AAG05710.1 - 2.9e-184 612.9 39.3 3.3e-184 612.7 39.3 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 AAG05710.1 - 3.8e-22 78.8 41.3 3.8e-22 78.8 41.3 1.5 1 1 0 1 1 1 1 Citrate transporter Na_H_antiport_2 PF13726.6 AAG05710.1 - 7.3e-05 22.8 4.3 7.3e-05 22.8 4.3 3.6 3 1 0 3 3 3 2 Na+-H+ antiporter family Aldedh PF00171.22 AAG05711.1 - 3.1e-94 316.1 0.0 4.1e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Acyl-CoA_dh_2 PF08028.11 AAG05712.1 - 5.9e-16 59.0 13.2 5.9e-16 59.0 13.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05712.1 - 1.5e-08 34.7 0.0 2.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG05712.1 - 4.7e-06 27.2 2.0 5.2e-06 27.1 0.2 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAG05712.1 - 0.0053 17.0 7.2 0.012 15.8 7.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG05712.1 - 0.018 14.7 0.0 0.054 13.2 0.0 1.7 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal ArdA PF07275.11 AAG05712.1 - 0.093 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Antirestriction protein (ArdA) T2SSF PF00482.23 AAG05712.1 - 0.28 11.2 1.7 0.87 9.5 0.4 2.5 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Acyl-CoA_dh_2 PF08028.11 AAG05713.1 - 4.4e-22 78.8 11.1 4.4e-22 78.8 11.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG05713.1 - 2.5e-10 41.0 1.0 1.2e-09 38.8 0.0 2.4 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05713.1 - 1.1e-09 38.4 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 AAG05713.1 - 4.9e-09 36.6 5.4 8.9e-09 35.7 5.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG05713.1 - 0.0048 16.6 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Bac_luciferase PF00296.20 AAG05714.1 - 5.6e-53 180.4 2.2 7.3e-53 180.0 2.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase BPD_transp_1 PF00528.22 AAG05715.1 - 3.4e-21 75.8 12.1 3.4e-21 75.8 12.1 1.9 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component NMT1_2 PF13379.6 AAG05716.1 - 2.5e-44 151.9 0.8 4.4e-44 151.1 0.8 1.4 1 1 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAG05716.1 - 1.7e-05 24.9 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like TAT_signal PF10518.9 AAG05716.1 - 0.0011 18.8 0.5 0.0011 18.8 0.5 2.2 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence ABC_tran PF00005.27 AAG05717.1 - 1e-29 103.8 0.0 1.6e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAG05717.1 - 6.9e-06 26.5 4.3 1e-05 26.0 2.6 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AAG05717.1 - 9.5e-06 25.6 0.1 0.03 14.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAG05717.1 - 0.00013 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 AAG05717.1 - 0.0084 15.9 0.8 0.2 11.3 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 AAG05717.1 - 0.013 15.7 0.6 0.15 12.4 0.4 2.5 2 1 0 2 2 1 0 AAA domain AAA_29 PF13555.6 AAG05717.1 - 0.02 14.6 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 AAG05717.1 - 0.034 14.4 0.1 0.075 13.3 0.1 1.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 AAG05717.1 - 0.04 14.0 0.1 0.085 12.9 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AAG05717.1 - 0.049 13.8 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAG05717.1 - 0.052 13.8 0.5 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 AAG05717.1 - 0.055 13.9 0.1 0.68 10.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAG05717.1 - 0.067 13.1 0.2 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 AAG05717.1 - 0.15 11.4 0.1 15 5.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 AAG05717.1 - 0.16 12.0 0.5 1.7 8.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AAG05717.1 - 0.17 11.8 0.0 1 9.2 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Acyl-CoA_dh_N PF02771.16 AAG05718.1 - 2.2e-07 31.5 0.0 6.2e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05718.1 - 0.15 12.2 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain CMD PF02627.20 AAG05719.1 - 1.3e-10 41.2 2.3 4.1e-10 39.6 0.5 2.2 1 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family Cupin_6 PF12852.7 AAG05720.1 - 1e-30 106.8 3.7 2.1e-30 105.8 3.7 1.4 1 0 0 1 1 1 1 Cupin HTH_18 PF12833.7 AAG05720.1 - 1.5e-21 76.4 2.3 2.8e-21 75.6 2.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05720.1 - 2.9e-13 49.5 0.0 1.1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG05720.1 - 0.00011 22.1 0.5 0.00039 20.3 0.1 2.1 1 1 0 2 2 2 1 AraC-like ligand binding domain HTH_IclR PF09339.10 AAG05720.1 - 0.00067 19.4 0.4 0.0088 15.8 0.0 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 AAG05720.1 - 0.0039 17.0 0.6 0.53 10.2 0.0 2.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain RHH_1 PF01402.21 AAG05720.1 - 0.031 14.2 0.0 0.094 12.7 0.0 1.9 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family MarR_2 PF12802.7 AAG05720.1 - 0.05 13.5 0.7 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 MarR family TetR_N PF00440.23 AAG05720.1 - 0.081 12.7 4.4 3 7.7 0.0 3.4 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family HTH_11 PF08279.12 AAG05720.1 - 0.094 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 AAG05720.1 - 0.15 12.2 2.0 0.37 10.9 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_31 PF13560.6 AAG05720.1 - 1.8 9.0 9.2 4.7 7.6 0.1 3.6 4 0 0 4 4 4 0 Helix-turn-helix domain Sulfatase PF00884.23 AAG05721.1 - 5.1e-58 196.9 0.0 7.2e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AAG05721.1 - 1.2e-11 44.8 0.0 6.1e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 AAG05721.1 - 4.3e-06 26.9 0.0 8.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 AAG05721.1 - 0.00094 17.9 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 AAG05721.1 - 0.0029 16.8 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) LysR_substrate PF03466.20 AAG05722.1 - 1.8e-28 99.3 2.3 2.5e-28 98.9 2.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05722.1 - 2.5e-17 62.6 1.2 5.5e-17 61.5 1.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family TonB_dep_Rec PF00593.24 AAG05723.1 - 3.7e-34 119.4 38.5 3.7e-34 119.4 38.5 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG05723.1 - 3.7e-15 56.4 0.7 3.7e-15 56.4 0.7 2.9 4 0 0 4 4 4 1 TonB-dependent Receptor Plug Domain Arylsulfotrans PF05935.11 AAG05724.1 - 3.6e-23 82.1 0.0 1.4e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 AAG05724.1 - 6.6e-19 68.4 0.0 1.1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 AAG05724.1 - 5.1 7.2 0.0 5.1 7.2 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat HTH_18 PF12833.7 AAG05725.1 - 2.4e-22 79.0 0.6 7.2e-22 77.5 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05725.1 - 2.7e-16 59.2 0.3 2e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Crp_2 PF13545.6 AAG05725.1 - 2.5e-05 24.2 0.0 9.4e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain AraC_binding PF02311.19 AAG05725.1 - 0.00074 19.4 0.4 0.0016 18.3 0.4 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain MarR_2 PF12802.7 AAG05725.1 - 0.0013 18.6 0.0 0.0058 16.5 0.0 2.2 2 1 0 2 2 2 1 MarR family HTH_31 PF13560.6 AAG05725.1 - 0.002 18.4 0.0 0.0095 16.3 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG05725.1 - 0.022 14.5 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 AAG05725.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix SBP_bac_1 PF01547.25 AAG05726.1 - 2.6e-47 162.3 4.4 3.7e-47 161.8 4.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAG05726.1 - 1.5e-24 87.3 2.9 2.3e-24 86.7 2.9 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 AAG05727.1 - 7.1e-17 61.7 21.2 7.1e-17 61.7 21.2 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG05728.1 - 5.9e-16 58.7 11.2 5.9e-16 58.7 11.2 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAG05729.1 - 2.9e-32 112.1 0.0 4.2e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAG05729.1 - 1.5e-11 44.3 0.0 4.9e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AAG05729.1 - 4.6e-08 33.2 0.3 0.0016 18.3 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 AAG05729.1 - 1.8e-07 31.8 0.1 1.5e-06 28.9 0.0 2.7 2 0 0 2 2 2 1 MalK OB fold domain TOBE PF03459.17 AAG05729.1 - 6.1e-06 26.4 0.0 0.00079 19.7 0.0 3.1 2 1 0 2 2 2 1 TOBE domain AAA_16 PF13191.6 AAG05729.1 - 0.00014 22.3 0.2 0.0003 21.2 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG05729.1 - 0.00021 21.2 0.1 0.0005 20.0 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase CysA_C_terminal PF17850.1 AAG05729.1 - 0.0019 18.7 0.5 0.025 15.2 0.0 3.0 4 0 0 4 4 2 1 CysA C-terminal regulatory domain SMC_N PF02463.19 AAG05729.1 - 0.0028 17.1 0.0 0.08 12.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG05729.1 - 0.003 18.1 0.0 0.0042 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAG05729.1 - 0.0052 16.7 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AAG05729.1 - 0.0066 16.7 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG05729.1 - 0.0068 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AAG05729.1 - 0.0096 16.4 0.1 0.027 14.9 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAG05729.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAG05729.1 - 0.014 15.5 0.3 0.036 14.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG05729.1 - 0.034 13.9 0.1 0.073 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 AAG05729.1 - 0.047 13.9 0.4 0.1 12.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAG05729.1 - 0.049 13.7 0.0 0.082 13.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 AAG05729.1 - 0.1 12.6 0.5 0.26 11.3 0.1 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAG05729.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 AAG05729.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 AAG05729.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 AAG05729.1 - 0.14 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 AAG05729.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 AAG05729.1 - 0.16 11.5 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mannitol_dh_C PF08125.13 AAG05730.1 - 3.4e-76 256.0 0.0 4.6e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 AAG05730.1 - 5.3e-47 159.8 0.0 7.5e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain FGGY_N PF00370.21 AAG05731.1 - 2.3e-62 210.7 0.0 3e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AAG05731.1 - 4.9e-32 111.3 0.6 4.9e-32 111.3 0.6 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Pentapeptide PF00805.22 AAG05731.1 - 0.068 12.8 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) HSP70 PF00012.20 AAG05731.1 - 0.12 10.6 0.0 0.9 7.6 0.0 1.9 1 1 1 2 2 2 0 Hsp70 protein PfkB PF00294.24 AAG05732.1 - 2e-28 99.6 0.0 2.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Diphthami_syn_2 PF01902.17 AAG05732.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Diphthamide synthase Pyr_redox_2 PF07992.14 AAG05733.1 - 4.2e-11 42.6 0.0 6e-08 32.3 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAG05733.1 - 9.9e-05 21.5 0.0 0.0011 18.1 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAG05733.1 - 0.00011 22.2 0.0 0.01 15.9 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 AAG05733.1 - 0.0071 16.0 0.1 0.0094 15.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG05733.1 - 0.036 13.3 0.2 0.062 12.5 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 AAG05733.1 - 0.1 12.8 0.2 0.34 11.2 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAG05733.1 - 0.21 10.3 0.1 0.31 9.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Acyl-CoA_dh_2 PF08028.11 AAG05734.1 - 2.4e-21 76.4 9.3 2.4e-21 76.4 9.3 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05734.1 - 3.2e-10 40.1 0.0 8.1e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG05734.1 - 2.2e-09 38.0 2.6 3.3e-08 34.2 0.0 3.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAG05734.1 - 8.6e-07 29.3 4.7 1.8e-06 28.3 4.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG05734.1 - 0.0016 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_2 PF08028.11 AAG05735.1 - 3.3e-20 72.7 6.2 3.3e-20 72.7 6.2 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 AAG05735.1 - 3.5e-11 43.5 2.5 3.5e-11 43.5 2.5 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG05735.1 - 6e-11 43.0 0.1 1.8e-10 41.5 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05735.1 - 6.7e-08 32.6 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Bac_luciferase PF00296.20 AAG05736.1 - 4.5e-60 203.7 6.3 7.3e-60 203.0 6.3 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase Helicase_RecD PF05127.14 AAG05736.1 - 0.055 13.3 0.0 0.29 10.9 0.0 2.1 1 1 1 2 2 2 0 Helicase Lipoprotein_9 PF03180.14 AAG05737.1 - 8.5e-75 250.9 0.0 9.5e-75 250.7 0.0 1.0 1 0 0 1 1 1 1 NLPA lipoprotein PepSY_2 PF13670.6 AAG05737.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ABC_tran PF00005.27 AAG05738.1 - 1.2e-35 123.0 0.0 1.8e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter NIL PF09383.10 AAG05738.1 - 5e-12 45.5 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 AAG05738.1 - 1.3e-06 28.4 0.1 0.01 15.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG05738.1 - 4.9e-05 22.9 0.1 0.00035 20.1 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG05738.1 - 6.1e-05 23.3 0.1 0.00028 21.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG05738.1 - 0.00056 20.3 2.3 0.0013 19.1 1.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 AAG05738.1 - 0.0016 17.9 0.1 0.15 11.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 AAG05738.1 - 0.0051 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAG05738.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAG05738.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 AAG05738.1 - 0.033 14.4 0.2 0.25 11.6 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 AAG05738.1 - 0.063 13.0 0.1 0.58 9.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAG05738.1 - 0.12 11.1 0.1 15 4.2 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 AAG05738.1 - 0.12 12.8 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAG05739.1 - 1.2e-24 87.0 10.6 1.2e-24 87.0 10.6 1.7 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component GDPD PF03009.17 AAG05740.1 - 3.7e-35 121.9 0.0 1.1e-34 120.3 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Form-deh_trans PF09163.11 AAG05740.1 - 2.3 8.0 7.6 0.3 10.9 0.9 2.4 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane AFG1_ATPase PF03969.16 AAG05741.1 - 6.1e-99 331.3 0.6 4.6e-82 275.8 0.0 2.8 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 AAG05741.1 - 0.0071 16.7 0.2 0.026 14.9 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 AAG05741.1 - 0.022 14.2 0.0 0.058 12.8 0.0 1.7 1 1 1 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 AAG05741.1 - 0.029 14.3 0.0 0.07 13.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 AAG05741.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 AAG05741.1 - 0.053 13.9 0.0 0.15 12.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 AAG05741.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 AAG05741.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 AAG05741.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 AAG05741.1 - 0.17 11.9 0.0 0.91 9.5 0.0 2.3 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AAG05742.1 - 2.5e-69 232.3 0.0 3.7e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG05742.1 - 6.7e-21 74.9 0.0 1.5e-20 73.7 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAG05742.1 - 3.8e-07 30.2 0.0 7.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_8 PF02954.19 AAG05742.1 - 0.0002 21.0 0.1 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_16 PF13191.6 AAG05742.1 - 0.00029 21.2 1.5 0.003 18.0 1.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AAG05742.1 - 0.00097 18.6 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAG05742.1 - 0.0015 18.9 0.0 0.0038 17.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAG05742.1 - 0.033 14.3 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 AAG05742.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_30 PF13556.6 AAG05742.1 - 0.84 9.5 3.5 0.33 10.8 0.4 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Acyl-CoA_dh_2 PF08028.11 AAG05743.1 - 1.4e-16 61.0 2.3 1.4e-16 61.0 2.3 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG05743.1 - 4e-12 46.8 0.5 8e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAG05743.1 - 4.3e-10 40.0 2.0 1.1e-09 38.7 2.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05743.1 - 1.4e-06 28.4 0.0 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Bac_luciferase PF00296.20 AAG05744.1 - 6.3e-94 314.9 6.9 7.3e-94 314.7 6.9 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase FMN_red PF03358.15 AAG05745.1 - 8.6e-30 103.5 0.0 1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AAG05745.1 - 1.5e-08 34.6 0.0 2.7e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Sigma54_activat PF00158.26 AAG05747.1 - 2.5e-68 229.0 0.0 4.6e-68 228.2 0.0 1.4 2 0 0 2 2 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG05747.1 - 8.5e-21 74.5 0.0 2.5e-20 73.0 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAG05747.1 - 7.4e-09 35.7 0.0 2.8e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG05747.1 - 0.00023 20.6 0.0 0.08 12.3 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAG05747.1 - 0.00069 20.1 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 AAG05747.1 - 0.00088 19.0 0.1 0.0031 17.3 0.1 1.9 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_8 PF02954.19 AAG05747.1 - 0.0057 16.4 0.0 0.021 14.6 0.0 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_16 PF13191.6 AAG05747.1 - 0.0073 16.7 1.1 0.017 15.5 1.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 AAG05747.1 - 0.0097 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) FixP_N PF14715.6 AAG05747.1 - 0.082 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF2089 PF09862.9 AAG05747.1 - 0.12 12.4 0.0 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2089) AAA_3 PF07726.11 AAG05747.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UBA_6 PF18039.1 AAG05747.1 - 0.17 11.8 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain Sigma70_r4 PF04545.16 AAG05747.1 - 0.49 9.9 2.7 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 ImpA_N PF06812.12 AAG05748.1 - 1.7e-36 124.9 1.8 1.7e-36 124.9 1.8 2.2 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system ANTH PF07651.16 AAG05748.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 ANTH domain TPR_6 PF13174.6 AAG05748.1 - 0.16 12.7 2.5 0.91 10.3 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat ImcF-related_N PF14331.6 AAG05749.1 - 4e-50 170.6 4.1 4e-50 170.6 4.1 2.1 2 0 0 2 2 2 1 ImcF-related N-terminal domain IcmF_C PF06744.12 AAG05749.1 - 0.006 16.2 3.5 0.27 10.8 3.5 2.6 1 1 0 1 1 1 1 Type VI secretion protein IcmF C-terminal HMG_box PF00505.19 AAG05749.1 - 0.11 12.9 0.1 0.59 10.6 0.0 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box DotU PF09850.9 AAG05750.1 - 4.4e-30 105.0 2.4 5.6e-30 104.6 2.4 1.2 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_VasE PF05936.12 AAG05751.1 - 3e-34 118.5 0.0 3.7e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE LPAM_1 PF08139.12 AAG05752.1 - 0.036 14.6 1.0 0.082 13.4 1.0 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site T6SS_VipA PF05591.12 AAG05753.1 - 3.5e-54 182.8 1.7 4.2e-54 182.6 1.7 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 VipB PF05943.12 AAG05754.1 - 1.8e-192 639.8 0.0 2.1e-192 639.5 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath TssC PF17541.2 AAG05754.1 - 0.037 12.8 0.7 0.082 11.7 0.7 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB CRR7 PF12095.8 AAG05754.1 - 0.046 14.2 0.0 11 6.5 0.0 2.8 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 T6SS_HCP PF05638.12 AAG05755.1 - 4.1e-29 101.6 0.0 5.4e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp GPW_gp25 PF04965.14 AAG05756.1 - 2.6e-17 62.3 0.2 3.3e-17 62.0 0.2 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme T6SS_TssF PF05947.12 AAG05757.1 - 1.7e-192 641.2 0.1 1.9e-192 641.1 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF T6SS_TssG PF06996.11 AAG05758.1 - 1.1e-73 248.1 6.6 1.3e-73 247.9 6.6 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG AAA_2 PF07724.14 AAG05759.1 - 5e-37 127.6 0.0 2.9e-36 125.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAG05759.1 - 5.4e-30 103.4 0.1 1.9e-29 101.7 0.1 2.0 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AAG05759.1 - 1.6e-20 73.9 0.1 2.9e-10 40.7 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAG05759.1 - 1.3e-14 54.3 0.1 4.4e-10 39.7 0.0 3.0 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 AAG05759.1 - 9.5e-12 44.9 7.1 2.3e-10 40.4 0.3 3.4 3 0 0 3 3 2 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 AAG05759.1 - 2.1e-08 34.8 10.8 6.4e-05 23.4 0.1 5.7 5 1 0 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 AAG05759.1 - 9e-08 32.5 0.4 0.29 11.4 0.0 5.6 3 1 1 5 5 5 2 AAA domain ClpB_D2-small PF10431.9 AAG05759.1 - 7.1e-06 26.0 0.1 1.8e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 AAG05759.1 - 1.8e-05 24.5 0.1 0.00072 19.3 0.0 3.1 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_25 PF13481.6 AAG05759.1 - 2.3e-05 24.1 1.9 0.019 14.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 AAG05759.1 - 8.6e-05 22.1 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 AAG05759.1 - 0.00029 20.2 0.0 0.051 12.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 AAG05759.1 - 0.00045 20.3 0.0 0.45 10.5 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 AAG05759.1 - 0.00056 19.1 0.0 0.0019 17.3 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 AAG05759.1 - 0.00082 19.9 0.1 2.8 8.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 AAG05759.1 - 0.0011 19.0 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAG05759.1 - 0.0011 18.7 0.1 1.8 8.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 AAG05759.1 - 0.0022 17.9 0.0 0.22 11.4 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 AAG05759.1 - 0.005 17.4 0.1 0.13 12.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 AAG05759.1 - 0.0066 16.8 0.0 3.6 8.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TniB PF05621.11 AAG05759.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.7 2 1 0 2 2 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 AAG05759.1 - 0.014 14.8 0.4 0.56 9.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 AAG05759.1 - 0.016 15.5 3.1 0.19 11.9 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.6 AAG05759.1 - 0.022 14.5 0.3 3.3 7.4 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 AAG05759.1 - 0.042 14.0 0.5 3.2 7.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 AAG05759.1 - 0.052 13.9 0.2 2.7 8.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 AAG05759.1 - 0.057 13.0 0.0 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 AAG05759.1 - 0.11 12.4 0.1 25 4.7 0.0 3.2 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea TsaE PF02367.17 AAG05759.1 - 0.13 12.2 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 AAG05759.1 - 0.14 11.3 0.0 2.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 AAG05759.1 - 0.19 11.4 0.3 19 5.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Ribosomal_L29 PF00831.23 AAG05759.1 - 0.96 9.5 6.6 3.2 7.8 0.6 3.7 4 0 0 4 4 4 0 Ribosomal L29 protein DUF4140 PF13600.6 AAG05759.1 - 1.8 9.1 8.4 7.2 7.1 0.2 3.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GreA_GreB_N PF03449.15 AAG05759.1 - 7.1 6.9 12.8 0.54 10.4 5.3 2.6 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF1192 PF06698.11 AAG05759.1 - 8.3 6.5 11.5 0.46 10.6 0.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4625 PF15418.6 AAG05760.1 - 0.05 13.8 0.0 0.072 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Peptidase_C80 PF11713.8 AAG05760.1 - 0.076 13.3 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase C80 family Phage_GPD PF05954.11 AAG05761.1 - 1.6e-85 287.1 0.3 2.7e-85 286.3 0.3 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Gp5_C PF06715.12 AAG05761.1 - 1.2e-13 50.1 18.1 1.2e-06 28.2 0.1 4.9 4 0 0 4 4 4 3 Gp5 C-terminal repeat (3 copies) Cupin_3 PF05899.12 AAG05761.1 - 0.078 12.7 0.4 15 5.4 0.2 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF861) DUF3540 PF12059.8 AAG05761.1 - 0.093 12.6 1.7 0.12 12.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) DUF2345 PF10106.9 AAG05761.1 - 0.14 12.0 10.1 3.4 7.5 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) MORN_2 PF07661.13 AAG05762.1 - 6.8e-16 56.5 0.0 0.0024 17.9 0.0 5.0 4 1 0 4 4 4 4 MORN repeat variant MORN PF02493.20 AAG05762.1 - 0.38 10.7 8.3 26 5.0 0.0 5.2 5 1 1 6 6 6 0 MORN repeat DUF4280 PF14107.6 AAG05763.1 - 2.4e-27 95.9 0.0 2.7e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4280) GerE PF00196.19 AAG05764.1 - 1.9e-17 62.5 0.0 3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAG05764.1 - 2.8e-13 50.0 0.0 4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AAG05764.1 - 1.9e-08 33.9 0.1 4.3e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG05764.1 - 8.6e-06 25.2 0.1 2.4e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 AAG05764.1 - 0.0027 17.5 0.1 3.6 7.5 0.1 2.9 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain DUF742 PF05331.11 AAG05764.1 - 0.0027 17.5 0.2 0.0056 16.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_23 PF13384.6 AAG05764.1 - 0.0031 17.3 1.8 0.013 15.3 0.0 2.8 3 1 1 4 4 4 1 Homeodomain-like domain HTH_20 PF12840.7 AAG05764.1 - 0.0043 17.1 0.5 0.0043 17.1 0.5 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.6 AAG05764.1 - 0.016 14.8 0.1 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LexA_DNA_bind PF01726.16 AAG05764.1 - 0.037 13.8 0.1 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 LexA DNA binding domain HTH_38 PF13936.6 AAG05764.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AAG05764.1 - 0.077 13.1 2.5 0.24 11.6 0.0 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain SBP_bac_6 PF13343.6 AAG05765.1 - 2.1e-10 40.5 0.0 3.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG05765.1 - 0.00015 21.6 0.9 0.00029 20.7 0.9 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG05765.1 - 0.0028 17.7 3.4 0.007 16.4 2.7 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAG05765.1 - 0.011 15.5 0.5 0.52 10.1 0.5 2.2 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF3046 PF11248.8 AAG05765.1 - 0.033 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) Ald_Xan_dh_C2 PF02738.18 AAG05766.1 - 7.7e-65 219.4 0.0 8.7e-29 100.4 0.0 3.1 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase TAT_signal PF10518.9 AAG05766.1 - 0.0016 18.2 0.2 0.0016 18.2 0.2 2.3 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Ald_Xan_dh_C PF01315.22 AAG05766.1 - 0.046 14.1 0.1 0.18 12.2 0.0 1.9 1 1 1 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 AAG05767.1 - 4.1e-25 87.6 0.5 4.1e-25 87.6 0.5 1.5 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAG05767.1 - 6e-07 29.3 0.1 6e-07 29.3 0.1 1.9 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAG05767.1 - 2e-06 27.8 0.1 3.3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AAG05767.1 - 0.0011 18.7 4.2 0.0011 18.7 4.2 2.0 3 0 0 3 3 3 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Fer2_4 PF13510.6 AAG05767.1 - 0.0044 17.0 0.5 0.014 15.4 0.5 2.0 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Gly_rich_SFCGS PF14272.6 AAG05767.1 - 0.0045 17.0 0.9 0.012 15.7 0.1 1.8 1 1 1 2 2 2 1 Glycine-rich SFCGS DUF1654 PF07867.11 AAG05769.1 - 6.8e-31 105.8 0.1 7.5e-31 105.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1654) FMN_dh PF01070.18 AAG05770.1 - 5e-136 453.3 0.1 5.7e-136 453.1 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AAG05770.1 - 6.7e-05 22.1 0.2 0.00022 20.4 0.1 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 AAG05770.1 - 7.6e-05 22.3 1.3 7.6e-05 22.3 1.3 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.17 AAG05770.1 - 0.00071 18.8 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 AAG05770.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein BtpA PF03437.15 AAG05770.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 BtpA family LysR_substrate PF03466.20 AAG05771.1 - 3.8e-23 82.0 11.7 6.3e-23 81.2 11.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05771.1 - 1.3e-15 57.1 2.9 3.6e-15 55.7 2.9 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family RIX1 PF08167.12 AAG05771.1 - 0.02 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Penicillinase_R PF03965.16 AAG05772.1 - 0.0074 16.6 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor FUR PF01475.19 AAG05772.1 - 0.069 13.3 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Ferric uptake regulator family Penicil_amidase PF01804.18 AAG05773.1 - 1.7e-142 476.8 5.4 1.9e-142 476.6 5.4 1.0 1 0 0 1 1 1 1 Penicillin amidase K_oxygenase PF13434.6 AAG05774.1 - 2.4e-121 405.1 0.0 2.8e-121 404.8 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 AAG05774.1 - 3.2e-08 33.7 1.0 1.4e-05 25.2 0.0 3.1 2 1 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 AAG05774.1 - 5.3e-06 25.9 0.0 0.00089 18.6 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAG05774.1 - 2.5e-05 23.6 0.0 0.0012 18.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sigma70_r4_2 PF08281.12 AAG05775.1 - 7.8e-16 57.5 0.4 2.6e-15 55.8 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG05775.1 - 8.1e-10 38.3 1.8 1.4e-09 37.6 1.8 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG05775.1 - 4.1e-08 32.6 1.4 5e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG05775.1 - 1.7e-06 28.1 2.1 2.2e-06 27.7 2.1 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AAG05775.1 - 0.00021 21.0 0.0 0.00063 19.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain GerE PF00196.19 AAG05775.1 - 0.00037 20.0 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 AAG05775.1 - 0.0036 16.8 0.0 0.0098 15.4 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAG05775.1 - 0.0037 17.2 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 HTH domain PCI PF01399.27 AAG05775.1 - 0.0044 17.5 0.0 0.0088 16.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain Erythro-docking PF09277.11 AAG05775.1 - 0.032 14.1 2.4 0.037 13.9 0.1 2.3 2 1 1 3 3 3 0 Erythronolide synthase, docking HTH_40 PF14493.6 AAG05775.1 - 0.032 14.7 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 AAG05775.1 - 0.035 14.0 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_38 PF13936.6 AAG05775.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 AAG05775.1 - 0.075 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain FecR PF04773.13 AAG05776.1 - 8.6e-21 74.4 0.3 1.3e-20 73.8 0.3 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG05776.1 - 5.6e-14 51.8 8.6 5.6e-14 51.8 8.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) TIG PF01833.24 AAG05776.1 - 0.14 12.2 0.2 0.26 11.4 0.2 1.4 1 0 0 1 1 1 0 IPT/TIG domain HlyD_D23 PF16576.5 AAG05777.1 - 1.5e-21 76.6 9.7 7.6e-20 71.1 8.6 2.5 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG05777.1 - 3e-16 60.0 3.9 2e-12 47.8 0.1 2.9 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG05777.1 - 3.5e-10 39.5 6.0 2e-07 30.7 0.5 3.7 3 0 0 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG05777.1 - 1.1e-06 28.4 0.1 0.0013 18.5 0.1 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme OEP PF02321.18 AAG05777.1 - 6.8e-05 22.7 13.7 0.00011 22.1 13.7 1.4 1 0 0 1 1 1 1 Outer membrane efflux protein RnfC_N PF13375.6 AAG05777.1 - 0.00012 22.0 0.1 0.78 9.7 0.0 2.5 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 AAG05777.1 - 0.004 17.3 0.1 0.55 10.5 0.0 2.7 2 0 0 2 2 2 1 Peptidase family M23 PTS_EIIA_1 PF00358.20 AAG05777.1 - 0.0045 16.7 0.0 0.25 11.1 0.0 2.5 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Cofilin_ADF PF00241.20 AAG05777.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Atg14 PF10186.9 AAG05777.1 - 0.38 9.8 3.1 0.53 9.3 3.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIA PF03153.13 AAG05777.1 - 1.3 8.9 8.1 2 8.3 8.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dppa2_A PF14049.6 AAG05777.1 - 2.4 8.4 5.6 0.47 10.6 1.8 1.8 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates DUF4407 PF14362.6 AAG05777.1 - 3.4 6.9 12.2 1.1 8.5 9.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 AAG05777.1 - 5.2 7.6 9.2 9.4 6.7 0.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.6 AAG05777.1 - 6.5 6.8 20.0 2.4 8.2 11.8 2.4 1 1 1 2 2 2 0 FlxA-like protein MacB_PCD PF12704.7 AAG05778.1 - 9.2e-38 130.6 2.3 9.2e-38 130.6 2.3 2.1 2 0 0 2 2 1 1 MacB-like periplasmic core domain ABC_tran PF00005.27 AAG05778.1 - 1.3e-31 109.9 0.0 2.4e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FtsX PF02687.21 AAG05778.1 - 1.5e-09 38.2 3.4 1.5e-09 38.2 3.4 2.9 3 0 0 3 3 3 1 FtsX-like permease family SMC_N PF02463.19 AAG05778.1 - 1.2e-05 24.9 0.1 0.044 13.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG05778.1 - 0.00042 20.0 0.1 0.001 18.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 AAG05778.1 - 0.00081 18.6 2.4 0.00093 18.4 0.5 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 AAG05778.1 - 0.0048 16.8 0.9 0.031 14.1 0.1 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG05778.1 - 0.006 17.0 2.3 0.037 14.4 0.4 2.6 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 AAG05778.1 - 0.013 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAG05778.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AAG05778.1 - 0.086 13.0 0.4 0.89 9.7 0.3 2.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAG05778.1 - 0.087 12.5 4.3 1.6 8.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 AAG05778.1 - 0.1 12.8 0.1 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAG05778.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain HRG PF16954.5 AAG05778.1 - 0.13 12.7 0.2 0.6 10.6 0.2 2.1 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene AAA_23 PF13476.6 AAG05778.1 - 0.2 12.1 0.2 0.37 11.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAG05778.1 - 0.28 11.3 0.7 0.58 10.2 0.7 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DUF4064 PF13273.6 AAG05778.1 - 1.2 9.5 16.4 19 5.6 11.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) OEP PF02321.18 AAG05779.1 - 4.2e-54 183.2 38.8 3.5e-27 95.4 14.7 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein DUF5344 PF17279.2 AAG05779.1 - 0.11 13.1 0.1 0.8 10.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5344) FliJ PF02050.16 AAG05779.1 - 3.4 7.9 17.0 1.6 9.0 7.6 3.6 3 0 0 3 3 3 0 Flagellar FliJ protein TAT_signal PF10518.9 AAG05780.1 - 0.006 16.4 0.8 0.013 15.3 0.8 1.5 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Peptidase_M19 PF01244.21 AAG05781.1 - 5.4e-106 354.4 0.0 9e-106 353.6 0.0 1.3 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Aminotran_5 PF00266.19 AAG05782.1 - 2.6e-30 105.6 0.0 3.8e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAG05782.1 - 0.0037 15.8 0.0 0.0047 15.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FGE-sulfatase PF03781.16 AAG05783.1 - 2.6e-68 230.4 1.0 3e-68 230.2 1.0 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Formyl_trans_N PF00551.19 AAG05784.1 - 2.2e-06 27.5 0.0 1.2e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Formyl transferase ABC_tran PF00005.27 AAG05785.1 - 3.5e-28 98.8 0.0 6e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAG05785.1 - 2.3e-11 43.9 1.1 2.3e-11 43.9 1.1 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 AAG05785.1 - 9.3e-10 38.8 0.1 0.00033 20.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG05785.1 - 8e-08 32.0 0.1 0.00046 19.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG05785.1 - 9.7e-06 26.1 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAG05785.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAG05785.1 - 0.0015 19.1 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 AAG05785.1 - 0.0015 18.4 0.2 0.31 11.0 0.1 2.8 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 AAG05785.1 - 0.0039 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AAG05785.1 - 0.015 15.3 0.5 0.072 13.0 0.0 2.2 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AAG05785.1 - 0.018 15.0 0.1 0.075 13.0 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 AAG05785.1 - 0.026 14.6 0.0 0.16 12.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 AAG05785.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAG05785.1 - 0.033 13.0 0.2 6 5.5 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AAG05785.1 - 0.035 14.0 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 AAG05785.1 - 0.035 14.1 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 AAG05785.1 - 0.07 12.3 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 AAG05785.1 - 0.1 13.2 0.1 0.63 10.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAG05785.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 AAG05785.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DLIC PF05783.11 AAG05785.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Rad17 PF03215.15 AAG05785.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TonB_dep_Rec PF00593.24 AAG05786.1 - 7.4e-45 154.7 53.6 1.2e-44 154.0 37.5 2.4 1 1 1 2 2 2 2 TonB dependent receptor Plug PF07715.15 AAG05786.1 - 3.3e-17 63.0 1.5 6.8e-17 62.0 1.5 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG05786.1 - 5.2e-08 32.6 1.0 1.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Secretin and TonB N terminus short domain Condensation PF00668.20 AAG05787.1 - 2.6e-219 728.5 0.0 1.2e-108 363.7 0.0 2.2 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 AAG05787.1 - 1.4e-206 686.1 0.0 3.4e-102 342.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Thioesterase PF00975.20 AAG05787.1 - 1.7e-60 205.0 0.7 5.8e-60 203.3 0.1 2.3 3 0 0 3 3 3 1 Thioesterase domain AMP-binding_C PF13193.6 AAG05787.1 - 9e-28 97.1 0.6 5.2e-12 46.6 0.0 3.8 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AAG05787.1 - 1.2e-26 92.9 8.2 1.3e-12 47.8 0.1 5.5 6 0 0 6 6 6 2 Phosphopantetheine attachment site HALZ PF02183.18 AAG05787.1 - 0.0018 18.5 0.4 3.5 7.9 0.1 2.8 2 0 0 2 2 2 2 Homeobox associated leucine zipper DUF2974 PF11187.8 AAG05787.1 - 0.0035 16.9 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 AAG05787.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 AAG05787.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1192 PF06698.11 AAG05787.1 - 9.3 6.4 9.4 42 4.3 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) Condensation PF00668.20 AAG05788.2 - 1.4e-219 729.4 0.4 2.2e-109 366.2 0.1 2.1 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 AAG05788.2 - 1e-176 587.7 0.0 5.8e-88 295.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 AAG05788.2 - 7.7e-32 109.5 1.8 1.1e-13 51.4 0.0 4.5 4 0 0 4 4 4 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAG05788.2 - 2.1e-27 95.9 1.1 1.8e-15 57.6 0.5 3.7 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Condensation PF00668.20 AAG05790.1 - 0 1801.3 0.0 3.1e-108 362.4 0.0 6.1 6 0 0 6 6 6 6 Condensation domain AMP-binding PF00501.28 AAG05790.1 - 0 1263.0 0.0 6.8e-102 341.2 0.0 4.4 4 0 0 4 4 4 4 AMP-binding enzyme AMP-binding_C PF13193.6 AAG05790.1 - 1.2e-60 202.4 0.4 1.7e-14 54.5 0.4 5.3 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AAG05790.1 - 1.5e-59 198.2 9.6 1e-14 54.6 0.1 6.4 6 0 0 6 6 6 4 Phosphopantetheine attachment site AATase PF07247.12 AAG05790.1 - 4.8e-06 25.4 0.0 0.18 10.3 0.0 3.8 5 0 0 5 5 5 2 Alcohol acetyltransferase POTRA_1 PF08478.10 AAG05790.1 - 0.0043 17.3 0.9 34 4.8 0.0 4.4 4 0 0 4 4 4 0 POTRA domain, FtsQ-type HTH_AsnC-type PF13404.6 AAG05790.1 - 0.012 15.4 0.7 0.073 12.9 0.7 2.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain PepSY_TM PF03929.16 AAG05791.1 - 2.6e-60 204.5 8.2 3.2e-60 204.2 8.2 1.1 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AAG05791.1 - 0.00021 21.8 0.0 0.001 19.6 0.0 2.1 3 0 0 3 3 3 1 Peptidase propeptide and YPEB domain DUF4405 PF14358.6 AAG05791.1 - 0.0029 18.1 1.9 0.0029 18.1 1.9 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 AAG05791.1 - 0.0029 17.2 10.2 0.28 10.7 0.0 3.5 2 1 1 3 3 3 2 Prokaryotic cytochrome b561 ZnuA PF01297.17 AAG05795.1 - 1.3e-53 182.0 0.0 1.5e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DUF3090 PF11290.8 AAG05795.1 - 0.057 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) ABC_tran PF00005.27 AAG05796.1 - 9e-22 78.1 0.0 1.3e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAG05796.1 - 4.2e-05 23.1 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAG05796.1 - 0.0011 18.8 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAG05796.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG05796.1 - 0.019 14.8 0.2 0.035 14.0 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 AAG05796.1 - 0.02 14.5 0.1 0.06 12.9 0.1 1.8 1 1 1 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAG05796.1 - 0.034 14.4 0.1 2 8.7 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 AAG05796.1 - 0.043 13.0 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 AAG05796.1 - 0.087 13.1 0.0 0.28 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 AAG05796.1 - 0.22 10.4 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain ABC-3 PF00950.17 AAG05797.1 - 2.5e-51 174.7 29.9 2.9e-51 174.5 29.9 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AAG05797.1 - 2.7e-08 33.2 31.5 2.7e-08 33.2 31.5 1.4 1 1 0 1 1 1 1 FecCD transport family CBP_BcsG PF11658.8 AAG05797.1 - 0.098 11.0 8.6 0.13 10.6 8.6 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF2407_C PF13373.6 AAG05797.1 - 0.76 9.9 3.7 1.4 9.1 0.3 2.5 2 0 0 2 2 2 0 DUF2407 C-terminal domain ZnuA PF01297.17 AAG05798.1 - 3.5e-13 49.6 0.0 5.5e-13 48.9 0.0 1.2 1 1 0 1 1 1 1 Zinc-uptake complex component A periplasmic DNA_photolyase PF00875.18 AAG05798.1 - 0.1 12.6 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 DNA photolyase Thioesterase PF00975.20 AAG05799.1 - 2.8e-39 135.6 0.0 3.4e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AAG05799.1 - 6e-09 36.8 2.9 8.8e-09 36.3 2.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG05799.1 - 0.012 14.8 0.0 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG05799.1 - 0.051 13.2 0.0 0.92 9.1 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold HisKA_3 PF07730.13 AAG05799.1 - 0.072 13.6 0.1 0.22 12.1 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase MbtH PF03621.13 AAG05800.1 - 5.4e-25 86.6 0.1 6.7e-25 86.3 0.1 1.1 1 0 0 1 1 1 1 MbtH-like protein Aminotran_3 PF00202.21 AAG05801.1 - 2.3e-88 296.6 0.0 2.8e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAG05801.1 - 0.0047 16.2 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II GSDH PF07995.11 AAG05802.1 - 6.7e-16 58.5 0.1 6.4e-14 52.0 0.0 3.2 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 AAG05802.1 - 0.15 12.1 1.5 12 6.1 0.1 3.1 3 0 0 3 3 3 0 NHL repeat Trehalase PF01204.18 AAG05804.1 - 4.5e-171 570.1 0.0 6.7e-171 569.6 0.0 1.2 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 AAG05804.1 - 0.017 14.0 0.0 0.12 11.3 0.0 2.0 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase LysR_substrate PF03466.20 AAG05805.1 - 2e-38 131.8 5.2 2.8e-38 131.4 5.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05805.1 - 5.1e-15 55.2 0.7 1.1e-14 54.1 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Pirin PF02678.16 AAG05806.1 - 1.9e-34 117.9 0.2 2.7e-34 117.4 0.2 1.2 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 AAG05806.1 - 1.9e-30 105.3 0.0 8.1e-30 103.2 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 AAG05806.1 - 0.00081 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Isochorismatase PF00857.20 AAG05807.1 - 5.4e-21 75.5 1.1 7e-21 75.2 0.3 1.6 2 0 0 2 2 2 1 Isochorismatase family Gaa1 PF04114.14 AAG05807.1 - 0.043 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component OprD PF03573.13 AAG05808.1 - 9.7e-137 456.2 0.6 1.1e-136 456.0 0.6 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Phenol_MetA_deg PF13557.6 AAG05809.1 - 9e-60 202.6 3.5 1e-59 202.4 3.5 1.0 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation Bro-N PF02498.17 AAG05811.1 - 1.2e-08 35.5 0.0 2.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 BRO family, N-terminal domain Condensation PF00668.20 AAG05812.1 - 0 1261.9 0.0 9.9e-105 350.8 0.0 4.1 4 0 0 4 4 4 4 Condensation domain AMP-binding PF00501.28 AAG05812.1 - 0 1233.8 0.0 2.8e-102 342.5 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.25 AAG05812.1 - 2.4e-60 200.8 0.4 9.3e-14 51.5 0.0 5.2 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAG05812.1 - 4.6e-38 130.0 1.9 2.6e-13 50.7 0.0 5.2 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Thump_like PF18096.1 AAG05812.1 - 0.098 12.6 0.0 1.9 8.5 0.0 3.3 2 0 0 2 2 2 0 THUMP domain-like Thioesterase PF00975.20 AAG05813.1 - 3e-53 181.3 0.0 3.6e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AAG05813.1 - 6.1e-06 27.0 9.0 8e-06 26.6 9.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG05813.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 AAG05813.1 - 0.023 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sigma70_r2 PF04542.14 AAG05814.1 - 1.1e-13 50.7 0.2 2e-13 49.9 0.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAG05814.1 - 9.4e-13 47.6 0.0 1.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG05814.1 - 1.5e-06 27.6 0.0 3.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 AAG05814.1 - 0.003 17.1 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 AAG05814.1 - 0.0063 16.4 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AAG05814.1 - 0.018 14.8 0.0 0.058 13.2 0.0 1.9 1 1 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAG05814.1 - 0.031 13.7 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AAG05814.1 - 0.037 13.8 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain KORA PF16509.5 AAG05814.1 - 0.04 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_3 PF01381.22 AAG05814.1 - 0.041 14.0 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix MarR_2 PF12802.7 AAG05814.1 - 0.061 13.2 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 MarR family RWP-RK PF02042.15 AAG05814.1 - 0.085 12.8 0.0 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 RWP-RK domain HTH_10 PF04967.12 AAG05814.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Phage_terminase PF10668.9 AAG05814.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit GerE PF00196.19 AAG05814.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family PPK2 PF03976.14 AAG05816.1 - 1e-116 388.3 0.8 1.3e-116 388.0 0.8 1.1 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) HSCB_C PF07743.13 AAG05816.1 - 0.075 13.5 1.4 0.73 10.4 0.1 2.7 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain SeqA PF03925.13 AAG05816.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 SeqA protein C-terminal domain HlyD_3 PF13437.6 AAG05818.1 - 2.1e-16 60.6 0.1 8.8e-11 42.5 0.0 3.2 2 2 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG05818.1 - 1.1e-15 57.2 9.8 2.7e-12 46.3 0.0 3.5 5 1 0 5 5 5 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG05818.1 - 8e-15 54.6 1.7 1.2e-13 50.8 1.7 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AAG05818.1 - 0.00049 19.9 0.0 0.76 9.6 0.0 2.7 3 0 0 3 3 3 2 Biotin-requiring enzyme HlyD PF00529.20 AAG05818.1 - 0.0024 17.7 0.2 0.0042 16.9 0.2 1.4 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS YfdX PF10938.8 AAG05818.1 - 0.063 13.2 6.2 2.7 7.9 0.9 2.4 1 1 0 2 2 2 0 YfdX protein FUSC PF04632.12 AAG05819.1 - 1.3e-154 516.3 64.8 1.6e-154 516.0 64.8 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAG05819.1 - 3.3e-15 56.3 13.2 3.3e-15 56.3 13.2 3.5 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AAG05819.1 - 0.0012 19.0 8.8 0.0012 19.0 8.8 3.5 2 2 0 2 2 2 1 Aromatic acid exporter family member 1 HTH_IclR PF09339.10 AAG05819.1 - 0.02 14.7 0.2 0.074 12.9 0.2 2.1 1 0 0 1 1 1 0 IclR helix-turn-helix domain ALMT PF11744.8 AAG05819.1 - 0.02 13.7 8.8 0.031 13.1 8.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LysR_substrate PF03466.20 AAG05820.1 - 9e-48 162.4 0.6 1.3e-47 161.9 0.2 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05820.1 - 2e-18 66.1 0.6 4.3e-18 65.0 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF4946 PF16304.5 AAG05822.1 - 6.3e-70 233.8 1.4 8.1e-70 233.4 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4946) E1-E2_ATPase PF00122.20 AAG05823.1 - 7.4e-49 165.7 0.2 7.4e-49 165.7 0.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 AAG05823.1 - 2.7e-28 99.7 1.4 5.1e-28 98.8 1.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Band_7 PF01145.25 AAG05825.1 - 3.4e-21 76.1 0.3 5.2e-21 75.5 0.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF3552 PF12072.8 AAG05825.1 - 0.025 14.0 2.6 0.045 13.2 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DivIVA PF05103.13 AAG05825.1 - 0.11 12.6 4.1 0.18 11.9 4.1 1.2 1 0 0 1 1 1 0 DivIVA protein Band_7 PF01145.25 AAG05826.1 - 1.7e-29 103.1 1.4 1.7e-29 103.1 1.4 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF5134 PF17197.4 AAG05826.1 - 0.0037 17.2 0.3 0.007 16.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5134) BCAS2 PF05700.11 AAG05826.1 - 0.023 14.4 1.4 0.041 13.6 1.4 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Taq-exonuc PF09281.10 AAG05826.1 - 0.28 11.2 4.5 0.26 11.3 2.3 2.0 2 0 0 2 2 2 0 Taq polymerase, exonuclease DivIVA PF05103.13 AAG05826.1 - 0.74 9.9 7.0 0.55 10.3 5.3 1.6 2 0 0 2 2 2 0 DivIVA protein Band_7 PF01145.25 AAG05827.1 - 5.5e-38 130.7 0.0 5.5e-38 130.7 0.0 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family Polysacc_deac_1 PF01522.21 AAG05828.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide deacetylase Myb_DNA-bind_6 PF13921.6 AAG05829.1 - 0.054 13.7 0.6 0.8 10.0 0.2 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain GCV_T PF01571.21 AAG05830.1 - 3.5e-90 301.9 0.0 4.2e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AAG05830.1 - 4.8e-18 64.8 0.2 1.2e-17 63.6 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 AAG05830.1 - 0.0047 17.1 0.0 0.42 10.7 0.0 2.4 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family DUF3659 PF12396.8 AAG05830.1 - 0.12 12.3 0.0 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) SDH_alpha PF03313.15 AAG05831.1 - 8.3e-106 353.4 6.1 1.1e-105 353.1 6.1 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 AAG05831.1 - 4.2e-58 196.1 0.0 7.2e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain SHMT PF00464.19 AAG05832.1 - 3.6e-180 598.8 0.1 4.1e-180 598.6 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AAG05832.1 - 9.4e-06 25.0 0.0 1.2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAG05832.1 - 6.9e-05 21.5 0.0 0.00013 20.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AAG05832.1 - 0.00014 21.2 0.1 0.0004 19.8 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAG05832.1 - 0.001 18.4 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 AAG05833.1 - 9.7e-194 644.1 0.0 6.8e-181 601.8 0.0 2.8 2 1 1 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 AAG05833.1 - 1.6e-05 24.3 0.1 3.6e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAG05833.1 - 2.4e-05 23.5 0.0 0.0019 17.3 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V GCV_H PF01597.19 AAG05834.1 - 5.7e-37 126.3 0.0 6.3e-37 126.2 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein LysR_substrate PF03466.20 AAG05835.1 - 2.2e-46 157.8 5.7 2.9e-46 157.5 5.7 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05835.1 - 4.3e-20 71.4 4.0 4.3e-20 71.4 4.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Amidohydro_3 PF07969.11 AAG05836.1 - 5.2e-75 253.7 6.8 8e-75 253.1 6.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AAG05836.1 - 9.8e-15 54.7 0.0 8.1e-11 41.8 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family Sigma54_activat PF00158.26 AAG05837.1 - 2.1e-64 216.3 0.0 3.1e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG05837.1 - 6.4e-21 74.9 0.0 2.1e-20 73.3 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_50 PF18024.1 AAG05837.1 - 9e-21 73.2 0.2 1.8e-20 72.3 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Mg_chelatase PF01078.21 AAG05837.1 - 2.4e-05 23.8 0.1 0.004 16.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI PAS_8 PF13188.7 AAG05837.1 - 9.5e-05 22.3 0.1 0.00034 20.6 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAG05837.1 - 0.00017 21.6 0.0 0.00062 19.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold AAA_5 PF07728.14 AAG05837.1 - 0.00018 21.5 0.0 0.00045 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAG05837.1 - 0.027 14.9 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ACT PF01842.25 AAG05837.1 - 0.036 13.8 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 ACT domain AAA_2 PF07724.14 AAG05837.1 - 0.046 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Esterase PF00756.20 AAG05839.1 - 6e-27 94.9 0.0 8.2e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AAG05839.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 AAG05839.1 - 0.02 14.5 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3327 PF11806.8 AAG05840.1 - 1.6e-19 70.8 1.8 3.1e-19 69.9 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3327) DUF903 PF06004.12 AAG05841.1 - 7.1e-19 67.4 0.2 8.1e-19 67.3 0.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) Methyltransf_25 PF13649.6 AAG05842.1 - 1e-10 42.1 0.0 1.8e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG05842.1 - 1.2e-10 41.4 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG05842.1 - 1.3e-09 38.6 0.0 2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG05842.1 - 8.9e-07 29.6 0.0 1.5e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 AAG05842.1 - 0.0054 16.4 0.0 0.017 14.8 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 AAG05842.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 AAG05842.1 - 0.075 12.4 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 AAG05842.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Acetyltransf_1 PF00583.25 AAG05843.1 - 2.5e-12 47.0 0.0 5.3e-12 46.0 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG05843.1 - 7.3e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG05843.1 - 0.00047 20.5 0.0 0.00093 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG05843.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 AAG05843.1 - 0.044 13.9 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RHS_repeat PF05593.14 AAG05845.1 - 1.4e-11 44.7 41.3 4.7e-08 33.4 5.2 7.2 5 2 2 7 7 7 4 RHS Repeat RHS_repeat PF05593.14 AAG05846.1 - 2.3e-54 181.3 55.3 2.7e-11 43.7 3.1 10.3 5 4 7 12 12 12 10 RHS Repeat Strep_pep PF14404.6 AAG05846.1 - 2.4 8.5 6.9 20 5.5 0.2 4.7 6 0 0 6 6 6 0 Ribosomally synthesized peptide in Streptomyces species PT-VENN PF04829.13 AAG05848.1 - 0.00069 19.6 0.1 0.00098 19.2 0.1 1.2 1 0 0 1 1 1 1 Pre-toxin domain with VENN motif Pentapeptide PF00805.22 AAG05849.1 - 7.6e-20 70.2 22.2 3.5e-07 29.7 1.2 4.0 1 1 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 AAG05849.1 - 1.6e-14 53.8 0.4 3.2e-05 24.0 0.1 3.6 2 2 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 AAG05849.1 - 4.5e-13 49.2 0.0 7.9e-07 29.2 0.0 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Fil_haemagg PF05594.14 AAG05850.1 - 7.7e-165 535.8 943.6 1.3e-07 32.1 2.0 71.8 17 10 42 60 60 60 43 Haemagluttinin repeat Haemagg_act PF05860.13 AAG05850.1 - 1.5e-33 115.3 7.5 2.5e-33 114.5 4.8 3.1 2 0 0 2 2 2 1 haemagglutination activity domain Fil_haemagg_2 PF13332.6 AAG05850.1 - 2.6e-16 60.2 9.9 6.2e-11 42.7 4.2 19.9 18 2 2 21 21 21 3 Hemagglutinin repeat EndoU_bacteria PF14436.6 AAG05850.1 - 7.6e-16 58.6 3.5 4.9e-15 56.0 3.5 2.3 1 1 0 1 1 1 1 Bacterial EndoU nuclease ANTAR PF03861.14 AAG05850.1 - 0.029 14.2 1.2 13 5.7 0.0 3.8 3 0 0 3 3 3 0 ANTAR domain ShlB PF03865.13 AAG05851.1 - 6.8e-98 328.0 10.0 8.4e-98 327.7 10.0 1.1 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AAG05851.1 - 4e-28 97.1 0.1 5.5e-27 93.4 0.1 2.4 2 0 0 2 2 2 1 POTRA domain, ShlB-type POTRA_3 PF17287.2 AAG05851.1 - 1.2e-15 56.6 0.1 4e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 POTRA domain POTRA PF07244.15 AAG05851.1 - 0.0093 16.5 0.0 0.055 14.0 0.0 2.2 2 0 0 2 2 2 1 Surface antigen variable number repeat PepSY_TM PF03929.16 AAG05853.1 - 1.4e-56 192.3 9.8 1.6e-56 192.1 9.8 1.0 1 0 0 1 1 1 1 PepSY-associated TM region TonB_dep_Rec PF00593.24 AAG05854.1 - 2.6e-70 238.6 28.6 2.6e-70 238.6 28.6 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG05854.1 - 2.6e-21 76.2 1.8 3.4e-21 75.8 0.3 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG05854.1 - 0.00011 21.9 0.0 0.00033 20.4 0.0 1.9 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain DUF560 PF04575.13 AAG05854.1 - 0.018 14.5 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF560) TrbC_Ftype PF09673.10 AAG05854.1 - 0.038 14.1 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein FecR PF04773.13 AAG05855.1 - 2.4e-18 66.6 0.1 4.1e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG05855.1 - 9.7e-14 51.0 13.9 9.7e-14 51.0 13.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) Hairy_orange PF07527.13 AAG05855.1 - 0.14 12.3 0.1 0.72 10.1 0.1 2.2 2 0 0 2 2 2 0 Hairy Orange Sigma70_r2 PF04542.14 AAG05856.1 - 3.8e-15 55.4 0.5 8.5e-15 54.3 0.5 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAG05856.1 - 9.8e-15 54.0 2.3 4.4e-14 51.9 0.4 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG05856.1 - 5.3e-07 29.7 0.2 7.2e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AAG05856.1 - 8.2e-07 28.5 0.1 2.9e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG05856.1 - 3.3e-05 23.6 0.8 0.00014 21.6 0.1 2.5 2 1 1 3 3 2 1 Homeodomain-like domain HTH_38 PF13936.6 AAG05856.1 - 0.004 16.9 0.2 0.023 14.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 AAG05856.1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AAG05856.1 - 0.0051 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AAG05856.1 - 0.0051 16.8 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix GerE PF00196.19 AAG05856.1 - 0.0088 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_Tnp_ISL3 PF13542.6 AAG05856.1 - 0.022 14.2 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.6 AAG05856.1 - 0.024 14.6 0.1 0.084 12.9 0.1 1.9 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 AAG05856.1 - 0.039 14.1 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 AAG05856.1 - 0.055 13.5 0.1 0.34 11.0 0.0 2.3 3 0 0 3 3 2 0 Helix-turn-helix DUF134 PF02001.16 AAG05856.1 - 0.069 13.7 0.0 0.13 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF134 PYRIN PF02758.16 AAG05856.1 - 0.11 12.7 0.1 0.28 11.4 0.1 1.8 1 1 0 1 1 1 0 PAAD/DAPIN/Pyrin domain TetR_N PF00440.23 AAG05856.1 - 0.13 12.1 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family MarR_2 PF12802.7 AAG05856.1 - 0.13 12.1 1.3 0.4 10.6 0.1 2.5 3 1 0 3 3 3 0 MarR family HTH_31 PF13560.6 AAG05856.1 - 0.15 12.4 3.8 0.67 10.3 1.1 3.0 1 1 1 2 2 2 0 Helix-turn-helix domain LysR_substrate PF03466.20 AAG05857.1 - 1.9e-38 132.0 4.7 3e-38 131.3 4.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05857.1 - 5.4e-19 67.9 0.0 1.2e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Cupin_2 PF07883.11 AAG05858.1 - 6.4e-31 105.9 0.0 1.4e-24 85.6 0.2 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 AAG05858.1 - 4.5e-06 26.3 0.2 0.031 14.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 AAG05858.1 - 5.6e-06 26.3 0.0 0.0067 16.3 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain ARD PF03079.14 AAG05858.1 - 0.028 14.6 0.0 0.098 12.8 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family FAA_hydrolase PF01557.18 AAG05859.1 - 5e-52 176.7 0.0 5.8e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 AAG05860.1 - 4.1e-51 174.0 69.1 1.7e-40 139.1 35.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG05860.1 - 1.9e-19 69.8 0.9 1.9e-19 69.8 0.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAG05860.1 - 4.5e-07 29.5 10.3 4.5e-07 29.5 10.3 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 AAG05860.1 - 0.86 7.8 13.6 0.061 11.5 3.0 2.8 3 0 0 3 3 3 0 BT1 family GST_N_3 PF13417.6 AAG05861.1 - 9e-14 51.6 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAG05861.1 - 3.4e-12 46.5 0.0 7.2e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG05861.1 - 4e-12 46.2 0.0 6.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAG05861.1 - 0.016 15.2 0.1 0.039 14.0 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF599 PF04654.12 AAG05861.1 - 0.037 13.5 0.1 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF599 Phenol_MetA_deg PF13557.6 AAG05862.1 - 1.8e-56 191.8 0.3 2.2e-56 191.5 0.3 1.1 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation p450 PF00067.22 AAG05863.1 - 7.1e-21 74.5 0.0 5.6e-14 51.7 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 Thioredoxin_2 PF13098.6 AAG05864.1 - 3.7e-16 59.5 0.0 6.2e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 AAG05864.1 - 2.8e-08 34.1 0.0 1.5e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin DsbC_N PF10411.9 AAG05864.1 - 0.00046 19.6 0.0 0.0015 18.0 0.0 1.8 2 0 0 2 2 2 1 Disulfide bond isomerase protein N-terminus DSBA PF01323.20 AAG05864.1 - 0.00091 19.1 1.3 0.21 11.3 0.2 2.4 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Sigma70_ner PF04546.13 AAG05864.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region AhpC-TSA PF00578.21 AAG05865.1 - 4.8e-15 55.6 0.0 6.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG05865.1 - 2.9e-14 53.0 0.0 4.9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 AAG05865.1 - 1.9e-05 24.6 0.0 5.7e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin LGT PF01790.18 AAG05865.1 - 2e-05 24.0 1.9 2.7e-05 23.5 1.9 1.2 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase Thioredoxin_8 PF13905.6 AAG05865.1 - 3.1e-05 24.2 0.0 4.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAG05865.1 - 0.00016 22.1 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 AAG05865.1 - 0.00023 20.9 0.0 0.00079 19.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 AAG05865.1 - 0.0034 17.5 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 AAG05865.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) SCO1-SenC PF02630.14 AAG05865.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC DsbC PF11412.8 AAG05866.1 - 7.5e-31 106.7 0.0 1.2e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredoxin_7 PF13899.6 AAG05866.1 - 8.6e-13 48.3 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.15 AAG05866.1 - 1.5e-10 41.4 15.5 2.4e-10 40.6 15.5 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AAG05866.1 - 4.1e-07 30.2 29.8 4.1e-07 30.2 29.8 2.9 2 1 1 3 3 3 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin PF00085.20 AAG05866.1 - 1.6e-05 24.8 0.0 2.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAG05866.1 - 6.3e-05 23.4 0.0 0.00017 22.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AAG05866.1 - 0.025 14.9 0.0 5.9 7.3 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin-like Thioredox_DsbH PF03190.15 AAG05866.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Response_reg PF00072.24 AAG05867.1 - 9.4e-25 87.0 0.1 1.2e-24 86.6 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG05867.1 - 4.4e-21 74.8 0.1 7.4e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HTH_11 PF08279.12 AAG05867.1 - 0.01 15.7 1.7 0.43 10.6 0.1 2.9 4 0 0 4 4 4 0 HTH domain OKR_DC_1_N PF03709.15 AAG05867.1 - 0.021 15.1 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain HATPase_c PF02518.26 AAG05868.1 - 3.3e-15 56.5 0.0 6.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2CSK_N PF08521.10 AAG05868.1 - 1.1e-09 38.5 1.4 2.5e-09 37.4 0.6 2.0 2 0 0 2 2 2 1 Two-component sensor kinase N-terminal HisKA PF00512.25 AAG05868.1 - 1.1e-09 38.2 2.5 1.1e-09 38.2 2.5 2.6 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAG05868.1 - 6.1e-06 26.2 0.4 2.1e-05 24.5 0.0 2.1 3 0 0 3 3 3 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAG05868.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 GHKL domain Cytochrome_CBB3 PF13442.6 AAG05869.1 - 8.4e-14 51.7 0.8 6.3e-11 42.4 0.2 2.5 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG05869.1 - 2.8e-11 44.4 1.0 1.1e-07 32.9 0.2 2.6 2 1 0 2 2 2 2 Cytochrome c Cytochrome_C7 PF14522.6 AAG05869.1 - 0.092 12.8 0.1 8.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_C1 PF02167.15 AAG05869.1 - 0.13 11.9 0.2 0.24 11.1 0.2 1.5 1 1 0 1 1 1 0 Cytochrome C1 family Cytochrom_C PF00034.21 AAG05870.1 - 4.3e-14 53.4 0.3 1.1e-05 26.5 0.0 2.8 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG05870.1 - 4.7e-13 49.3 0.5 3.5e-06 27.2 0.3 2.4 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III DUF1924 PF09086.11 AAG05870.1 - 0.00094 19.5 0.1 0.037 14.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1924) Paired_CXXCH_1 PF09699.10 AAG05870.1 - 0.0017 18.0 0.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AAG05870.1 - 0.072 13.1 0.0 12 6.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF3365 PF11845.8 AAG05870.1 - 0.073 13.4 0.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) PSCyt3 PF07627.11 AAG05870.1 - 0.1 12.9 0.0 4.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) PSCyt1 PF07635.11 AAG05870.1 - 0.13 12.9 1.4 18 6.0 0.0 2.7 2 0 0 2 2 2 0 Planctomycete cytochrome C Bac_luciferase PF00296.20 AAG05871.1 - 4.2e-39 134.8 1.2 6.7e-39 134.1 1.2 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_tranf_2_4 PF13704.6 AAG05871.1 - 0.15 12.5 0.2 0.38 11.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 TetR_N PF00440.23 AAG05872.1 - 8.1e-07 28.7 0.1 3.8e-06 26.6 0.2 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAG05872.1 - 1.8e-05 24.9 1.5 1.8e-05 24.9 1.5 1.8 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_11 PF16859.5 AAG05872.1 - 0.0057 17.0 1.6 0.015 15.6 1.5 2.0 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain ABATE PF07336.11 AAG05872.1 - 0.81 10.4 9.8 0.72 10.5 6.4 2.4 1 1 1 2 2 2 0 Putative stress-induced transcription regulator HTH_18 PF12833.7 AAG05876.1 - 5.4e-23 81.1 1.0 1.5e-22 79.7 0.4 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05876.1 - 3.6e-13 49.2 0.1 3.8e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG05876.1 - 2.7e-07 30.6 0.3 6.8e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG05876.1 - 0.016 14.9 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Cupin domain TilS PF09179.11 AAG05876.1 - 1.2 9.7 7.5 1.1 9.7 1.8 2.8 1 1 1 2 2 2 0 TilS substrate binding domain AraC_binding PF02311.19 AAG05877.1 - 1.6e-27 96.1 1.3 1.6e-27 96.1 1.3 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain HTH_18 PF12833.7 AAG05877.1 - 1.7e-19 69.8 1.3 1.7e-19 69.8 1.3 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05877.1 - 3.6e-07 30.1 0.0 0.00034 20.6 0.0 2.6 2 1 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG05878.1 - 4e-13 48.9 0.8 8.3e-13 47.8 0.5 1.6 1 1 1 2 2 2 1 Cupin domain Cupin_3 PF05899.12 AAG05878.1 - 0.00041 20.0 0.1 0.0006 19.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 AAG05878.1 - 0.00048 20.1 0.1 0.0019 18.1 0.1 1.8 1 1 1 2 2 2 1 AraC-like ligand binding domain Cupin_7 PF12973.7 AAG05878.1 - 0.00053 19.8 0.0 0.00079 19.3 0.0 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_1 PF00190.22 AAG05878.1 - 0.00084 19.0 0.0 0.0013 18.3 0.0 1.3 1 1 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 AAG05878.1 - 0.0022 17.9 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 AAG05878.1 - 0.0068 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like HgmA PF04209.13 AAG05878.1 - 0.012 14.4 0.0 0.015 14.0 0.0 1.2 1 1 0 1 1 1 0 homogentisate 1,2-dioxygenase cNMP_binding PF00027.29 AAG05878.1 - 0.045 13.8 0.0 0.18 11.9 0.0 1.9 1 1 1 2 2 2 0 Cyclic nucleotide-binding domain Cupin_6 PF12852.7 AAG05878.1 - 0.069 12.9 0.1 0.081 12.6 0.1 1.1 1 0 0 1 1 1 0 Cupin ADH_zinc_N_2 PF13602.6 AAG05879.1 - 1.4e-17 65.0 0.0 2.3e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AAG05879.1 - 5.3e-17 62.0 0.0 1.1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG05879.1 - 4.5e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 AAG05879.1 - 0.12 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 AAG05879.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain LysR_substrate PF03466.20 AAG05880.1 - 1.2e-19 70.5 0.7 1.2e-19 70.5 0.7 1.8 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05880.1 - 4.4e-08 33.0 0.1 8.1e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Biotin_lipoyl_2 PF13533.6 AAG05881.1 - 1.7e-18 66.2 0.4 5.6e-13 48.5 0.0 2.9 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG05881.1 - 9.1e-17 61.0 0.3 7e-16 58.1 0.3 2.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG05881.1 - 7.3e-09 36.3 0.4 0.00027 21.6 0.0 2.9 2 1 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AAG05881.1 - 3.5e-06 26.8 0.0 1.3e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG05881.1 - 0.001 18.9 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme RsmF_methylt_CI PF17126.5 AAG05881.1 - 0.036 14.1 0.1 0.14 12.2 0.0 2.0 1 1 1 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain ACR_tran PF00873.19 AAG05882.1 - 0 1323.3 10.0 0 1323.1 10.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG05882.1 - 1.7e-15 56.8 28.1 9.8e-10 37.9 12.4 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAG05882.1 - 5.7e-05 22.6 13.3 5.7e-05 22.6 13.3 2.5 2 0 0 2 2 2 2 Protein export membrane protein MASE5 PF17178.4 AAG05882.1 - 0.0097 15.8 2.6 0.0097 15.8 2.6 2.6 2 0 0 2 2 2 1 Membrane-associated sensor OEP PF02321.18 AAG05883.1 - 1.5e-44 152.0 30.3 3.1e-23 82.5 14.5 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein DUF3584 PF12128.8 AAG05883.1 - 1.1 6.7 18.0 0.011 13.4 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DinB PF05163.12 AAG05884.1 - 1.5e-41 142.1 0.0 1.7e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.7 AAG05884.1 - 1.1e-06 29.2 1.0 1.6e-06 28.7 0.7 1.3 1 1 0 1 1 1 1 DinB superfamily LysR_substrate PF03466.20 AAG05885.1 - 3.2e-30 105.1 4.8 4.1e-30 104.7 4.8 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05885.1 - 1.9e-21 75.8 0.3 4.9e-21 74.5 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG05885.1 - 0.0038 17.0 0.2 0.0038 17.0 0.2 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 AAG05885.1 - 1.3 8.9 4.2 5 7.1 0.2 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Ank_4 PF13637.6 AAG05886.1 - 8.4e-27 93.2 0.3 2.6e-08 34.2 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 AAG05886.1 - 2.8e-22 79.1 0.2 2e-12 47.5 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AAG05886.1 - 5.5e-17 61.6 2.6 4.1e-06 27.0 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 AAG05886.1 - 1.6e-15 55.6 0.5 0.0021 18.4 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 AAG05886.1 - 4.2e-14 52.2 5.7 0.0035 17.7 0.1 5.7 6 0 0 6 6 6 3 Ankyrin repeat GDPD_2 PF13653.6 AAG05886.1 - 0.19 12.2 0.0 20 5.8 0.0 3.2 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family MafB19-deam PF14437.6 AAG05887.1 - 1.2e-21 76.9 0.0 1.4e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AAG05887.1 - 9.2e-21 73.6 0.0 1.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 AAG05887.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 AAG05887.1 - 0.23 11.5 1.2 1.9 8.6 0.4 2.0 1 1 1 2 2 2 0 Bd3614-like deaminase MFS_1 PF07690.16 AAG05888.1 - 1.6e-27 96.3 41.7 1.6e-27 96.3 41.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG05888.1 - 7e-08 32.1 30.5 7.9e-07 28.7 17.9 2.1 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB Folate_carrier PF01770.18 AAG05888.1 - 0.048 12.4 0.2 0.075 11.7 0.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF1206 PF06724.11 AAG05889.1 - 0.31 11.2 6.4 2.3 8.4 6.4 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1206) TrbC PF04956.13 AAG05889.1 - 0.67 10.2 5.8 0.81 9.9 5.8 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family LRR_8 PF13855.6 AAG05890.1 - 1.6e-16 59.8 0.0 1.8e-05 24.4 0.0 3.6 3 0 0 3 3 3 3 Leucine rich repeat Pkinase_Tyr PF07714.17 AAG05890.1 - 3.5e-12 46.2 0.0 7.6e-11 41.8 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase LRR_4 PF12799.7 AAG05890.1 - 8.1e-12 45.2 0.1 2.3e-06 27.8 0.3 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 AAG05890.1 - 1.2e-07 31.3 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 AAG05890.1 - 2.4e-06 27.1 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AAG05890.1 - 3e-05 24.0 2.2 3e-05 24.0 2.2 2.9 2 2 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 AAG05890.1 - 0.00059 19.2 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_9 PF14580.6 AAG05890.1 - 0.0018 17.8 0.1 0.22 11.0 0.0 2.6 1 1 2 3 3 3 3 Leucine-rich repeat RsmF_methylt_CI PF17126.5 AAG05890.1 - 0.068 13.2 0.0 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain LRR_1 PF00560.33 AAG05890.1 - 0.58 10.9 3.5 6.1 7.8 0.3 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat SMI1_KNR4 PF09346.10 AAG05891.1 - 0.012 16.0 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Ank_4 PF13637.6 AAG05891.1 - 0.013 16.1 0.1 0.13 12.9 0.1 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF2185 PF09951.9 AAG05892.1 - 2.1e-31 107.6 0.0 3.5e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) DUF2314 PF10077.9 AAG05892.1 - 8.7e-07 29.1 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) OprD PF03573.13 AAG05893.1 - 6.7e-147 489.6 8.2 7.6e-147 489.5 8.2 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family TraY PF05509.11 AAG05894.1 - 0.0091 16.0 0.5 0.019 15.0 0.5 1.5 1 0 0 1 1 1 1 TraY domain Conotoxin PF02950.17 AAG05894.1 - 0.042 14.9 0.6 0.075 14.0 0.6 1.5 1 1 0 1 1 1 0 Conotoxin Peptidase_S49_N PF08496.10 AAG05894.1 - 0.055 13.5 1.2 0.061 13.4 1.2 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DivIC PF04977.15 AAG05894.1 - 0.056 13.2 2.9 0.064 13.0 2.9 1.1 1 0 0 1 1 1 0 Septum formation initiator PepSY_2 PF13670.6 AAG05894.1 - 0.18 11.8 4.7 0.38 10.8 4.7 1.6 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain TraW_N PF12477.8 AAG05894.1 - 0.6 10.1 3.5 0.88 9.6 3.5 1.2 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Dioxygenase_C PF00775.21 AAG05895.1 - 2.2e-67 226.0 0.0 3.2e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 AAG05895.1 - 1.5e-24 85.6 0.1 2.4e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 AAG05895.1 - 2.4e-06 27.7 0.0 9.7e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 AAG05895.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) MIase PF02426.16 AAG05896.1 - 9.8e-38 128.2 0.1 1.1e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Muconolactone delta-isomerase MR_MLE_C PF13378.6 AAG05897.1 - 1e-44 152.8 2.8 1.5e-44 152.2 2.8 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 AAG05897.1 - 6.9e-36 123.0 0.0 1.3e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 AAG05897.1 - 0.049 12.8 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus LysR_substrate PF03466.20 AAG05898.1 - 1.5e-35 122.5 5.3 2.1e-35 122.0 5.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05898.1 - 5.7e-24 83.8 2.4 1.2e-23 82.8 2.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG05898.1 - 0.011 15.6 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AAG05898.1 - 0.066 12.8 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AraC_binding_2 PF14525.6 AAG05899.1 - 1.7e-36 125.5 0.4 2.4e-36 125.0 0.4 1.2 1 0 0 1 1 1 1 AraC-binding-like domain HTH_18 PF12833.7 AAG05899.1 - 2.6e-23 82.1 2.2 3.6e-23 81.6 0.8 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05899.1 - 2.6e-08 33.8 0.1 0.00047 20.2 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Rieske PF00355.26 AAG05900.1 - 8.6e-23 80.1 0.1 1.5e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 AAG05900.1 - 9.4e-10 38.8 0.1 1.5e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Ring_hydroxyl_B PF00866.18 AAG05901.1 - 2.9e-48 163.6 0.0 3.4e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Ring hydroxylating beta subunit SnoaL_4 PF13577.6 AAG05901.1 - 2.5e-05 24.4 0.1 3.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain CaM-KIIN PF15170.6 AAG05901.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor SnoaL_2 PF12680.7 AAG05901.1 - 0.12 13.0 0.7 0.52 11.0 0.7 2.0 1 1 0 1 1 1 0 SnoaL-like domain FAD_binding_6 PF00970.24 AAG05902.1 - 1.5e-21 76.6 0.0 2.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AAG05902.1 - 2.5e-20 73.2 0.0 3.7e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AAG05902.1 - 6.4e-16 58.1 0.2 1.1e-15 57.4 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AAG05902.1 - 0.044 13.9 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain SIP PF04954.13 AAG05902.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting protein adh_short_C2 PF13561.6 AAG05903.1 - 1.2e-48 165.7 0.0 2e-48 165.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG05903.1 - 1.4e-47 161.7 0.0 1.8e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG05903.1 - 0.016 15.1 0.3 0.034 14.0 0.3 1.7 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 AAG05903.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_1 PF00175.21 AAG05904.1 - 1.4e-22 80.4 0.0 2.2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAG05904.1 - 8.5e-17 61.3 0.0 1.5e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 AAG05904.1 - 2.5e-15 56.2 0.6 4.8e-15 55.3 0.6 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AAG05904.1 - 0.017 15.3 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Fer2_4 PF13510.6 AAG05904.1 - 0.023 14.7 1.3 0.13 12.3 1.3 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ring_hydroxyl_B PF00866.18 AAG05905.1 - 3.1e-48 163.5 0.3 3.5e-48 163.3 0.3 1.0 1 0 0 1 1 1 1 Ring hydroxylating beta subunit SnoaL_4 PF13577.6 AAG05905.1 - 2.3e-05 24.5 0.2 2.7e-05 24.3 0.2 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 AAG05905.1 - 0.013 16.1 0.2 0.023 15.4 0.2 1.5 1 0 0 1 1 1 0 SnoaL-like domain Rieske PF00355.26 AAG05906.1 - 1.2e-20 73.2 0.1 2.1e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 AAG05906.1 - 2.8e-18 66.7 0.1 4.5e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) HTH_18 PF12833.7 AAG05907.1 - 9.7e-26 89.9 1.8 2.2e-25 88.7 1.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding_2 PF14525.6 AAG05907.1 - 1.2e-25 90.2 2.9 1.2e-25 90.2 2.9 2.2 2 0 0 2 2 2 1 AraC-binding-like domain AraC_binding PF02311.19 AAG05907.1 - 4.6e-22 78.4 0.2 8.5e-22 77.5 0.2 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_AraC PF00165.23 AAG05907.1 - 8.1e-13 48.1 0.1 1.8e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family SeqA_N PF17206.3 AAG05907.1 - 0.73 9.2 2.4 12 5.3 0.1 2.3 2 0 0 2 2 2 0 SeqA protein N-terminal domain ACR_tran PF00873.19 AAG05908.1 - 0 1173.9 9.8 0 1173.7 9.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family HlyD_D23 PF16576.5 AAG05909.1 - 8.4e-42 142.8 0.1 2.1e-41 141.5 0.1 1.7 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG05909.1 - 9.5e-21 74.5 0.2 2.1e-17 63.7 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG05909.1 - 0.00015 21.5 0.0 0.00015 21.5 0.0 3.2 4 0 0 4 4 4 1 Biotin-lipoyl like OEP PF02321.18 AAG05909.1 - 0.011 15.6 7.0 0.022 14.6 7.0 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein HlyD PF00529.20 AAG05909.1 - 1.9 8.4 16.2 6.3e+02 0.3 16.2 2.4 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS OEP PF02321.18 AAG05910.1 - 4.5e-53 179.9 31.0 5e-27 94.9 7.7 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein Smac_DIABLO PF09057.10 AAG05910.1 - 2.2 7.6 8.0 0.68 9.2 3.8 2.2 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases Response_reg PF00072.24 AAG05911.1 - 1.5e-26 92.8 0.0 2.3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG05911.1 - 1.3e-25 89.3 0.0 2.9e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AAG05912.1 - 1.1e-23 83.9 0.0 2e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAG05912.1 - 8.9e-13 48.4 0.5 4e-12 46.3 0.1 2.4 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AAG05912.1 - 1.2e-07 31.6 4.0 1.6e-07 31.2 0.7 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAG05912.1 - 1.9e-05 24.6 0.1 4.9e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain TPR_5 PF12688.7 AAG05912.1 - 0.0098 16.1 1.8 0.018 15.3 0.3 2.2 2 0 0 2 2 2 1 Tetratrico peptide repeat Spore_III_AB PF09548.10 AAG05912.1 - 0.048 13.8 0.1 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) HPTransfase PF10090.9 AAG05912.1 - 0.056 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain LapA_dom PF06305.11 AAG05912.1 - 0.14 12.0 2.0 0.39 10.6 2.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FlaC_arch PF05377.11 AAG05912.1 - 0.2 12.0 0.6 1.4 9.4 0.0 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) OEP PF02321.18 AAG05913.1 - 3.2e-59 199.9 21.1 1.9e-30 106.1 1.8 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein DASH_Spc19 PF08287.11 AAG05913.1 - 0.016 15.1 2.9 0.037 13.9 0.3 2.5 2 1 0 2 2 2 0 Spc19 Pro_Al_protease PF02983.14 AAG05913.1 - 0.065 13.3 0.4 0.065 13.3 0.4 2.8 2 0 0 2 2 2 0 Alpha-lytic protease prodomain CtIP_N PF10482.9 AAG05913.1 - 0.17 11.9 3.8 1.3 9.1 1.8 2.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Sec8_exocyst PF04048.14 AAG05913.1 - 0.19 11.6 3.6 0.22 11.4 0.4 2.7 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain AAA_13 PF13166.6 AAG05913.1 - 0.32 9.6 1.3 0.5 9.0 1.3 1.2 1 0 0 1 1 1 0 AAA domain Tektin PF03148.14 AAG05913.1 - 1 8.0 9.3 0.052 12.3 0.6 2.6 3 0 0 3 3 3 0 Tektin family TPR_12 PF13424.6 AAG05913.1 - 2.3 8.6 9.3 0.17 12.2 0.8 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat ACR_tran PF00873.19 AAG05914.1 - 0 1087.1 6.2 0 1086.9 6.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG05914.1 - 3.6e-15 55.7 14.9 3.6e-10 39.3 6.0 2.3 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAG05914.1 - 3.5e-09 36.3 18.9 9e-06 25.2 8.4 2.4 2 0 0 2 2 2 2 Protein export membrane protein DUF3094 PF11293.8 AAG05914.1 - 0.074 12.8 0.1 0.074 12.8 0.1 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3094) ACR_tran PF00873.19 AAG05915.1 - 0 1120.2 19.5 0 1120.0 19.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG05915.1 - 7.6e-09 34.9 9.1 7.6e-09 34.9 9.1 2.9 3 0 0 3 3 3 1 MMPL family SecD_SecF PF02355.16 AAG05915.1 - 1.7e-06 27.5 26.9 0.00016 21.1 12.4 2.8 3 0 0 3 3 3 2 Protein export membrane protein Man-6-P_recep PF02157.15 AAG05915.1 - 0.28 10.2 0.4 0.54 9.3 0.4 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Patched PF02460.18 AAG05915.1 - 5.6 4.9 22.9 0.04 12.0 10.6 2.1 2 0 0 2 2 2 0 Patched family Biotin_lipoyl_2 PF13533.6 AAG05916.1 - 6.8e-15 54.6 0.2 6.8e-15 54.6 0.2 2.9 4 0 0 4 4 4 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG05916.1 - 1.9e-14 53.4 2.7 2.6e-14 53.0 2.7 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG05916.1 - 1.8e-10 41.5 6.8 7e-09 36.3 0.7 3.0 3 2 0 3 3 3 2 HlyD family secretion protein TPR_21 PF09976.9 AAG05916.1 - 0.00032 20.5 5.5 0.014 15.1 1.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain PTS_EIIA_1 PF00358.20 AAG05916.1 - 0.0046 16.7 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 VWA_3_C PF18571.1 AAG05916.1 - 0.015 15.2 1.1 0.06 13.2 0.1 2.5 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Biotin_lipoyl PF00364.22 AAG05916.1 - 0.027 14.3 3.6 0.052 13.4 0.1 2.8 3 0 0 3 3 3 0 Biotin-requiring enzyme Csm1_N PF18504.1 AAG05916.1 - 0.21 11.9 1.8 0.62 10.4 1.8 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain HrpB7 PF09486.10 AAG05916.1 - 0.57 10.6 6.2 0.77 10.1 1.0 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) FliJ PF02050.16 AAG05916.1 - 1.3 9.3 7.0 2.2 8.5 7.0 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4349 PF14257.6 AAG05916.1 - 6.8 6.1 14.7 0.8 9.1 2.4 3.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4349) PmbA_TldD PF01523.16 AAG05917.1 - 7.2e-44 150.7 0.0 1.3e-43 149.9 0.0 1.3 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 AAG05918.1 - 1.2e-28 100.8 0.0 1.7e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Aminotran_1_2 PF00155.21 AAG05919.1 - 4.3e-38 131.4 0.0 5.2e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAG05919.1 - 6.3e-07 28.7 0.0 9e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 AAG05919.1 - 0.00097 18.1 0.0 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 Allinase Redoxin PF08534.10 AAG05920.1 - 6.1e-28 97.4 0.0 7.2e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAG05920.1 - 5.4e-15 55.4 0.0 6.5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Na_Ala_symp PF01235.17 AAG05921.1 - 1.5e-141 472.3 28.0 1.9e-141 472.0 28.0 1.0 1 0 0 1 1 1 1 Sodium:alanine symporter family LysR_substrate PF03466.20 AAG05922.1 - 1.8e-44 151.6 5.7 1.8e-44 151.6 5.7 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05922.1 - 2e-15 56.5 2.1 4.2e-15 55.4 2.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF3301 PF11743.8 AAG05922.1 - 0.12 12.1 0.6 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Aldo_ket_red PF00248.21 AAG05923.1 - 2e-81 273.4 0.0 2.5e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CTP_transf_1 PF01148.20 AAG05924.1 - 8e-70 235.6 16.7 1.1e-69 235.2 16.7 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2633 PF11119.8 AAG05924.1 - 0.21 11.5 0.2 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Acyltransferase PF01553.21 AAG05925.1 - 1.6e-15 56.9 0.0 2.1e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase DUF1127 PF06568.11 AAG05926.1 - 0.019 14.7 0.4 0.019 14.7 0.4 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1127) DSPc PF00782.20 AAG05927.1 - 1.3e-08 34.7 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAP2_3 PF14378.6 AAG05927.1 - 3.7e-05 23.5 10.3 3.7e-05 23.5 10.3 2.7 3 2 0 3 3 3 1 PAP2 superfamily PAP2 PF01569.21 AAG05927.1 - 0.0055 16.5 8.4 0.0055 16.5 8.4 2.9 2 2 0 2 2 2 1 PAP2 superfamily Y_phosphatase PF00102.27 AAG05927.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PAP2_C PF14360.6 AAG05927.1 - 0.072 13.6 3.3 0.22 12.1 3.3 1.8 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Methyltransf_20 PF12147.8 AAG05928.1 - 1.8e-157 523.3 0.0 2.3e-157 522.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Hydrolase_4 PF12146.8 AAG05928.1 - 1.7e-65 220.7 0.3 3.1e-65 219.8 0.3 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG05928.1 - 3.1e-07 30.3 0.1 1.3e-06 28.3 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG05928.1 - 7.3e-05 23.5 14.1 0.0012 19.5 14.1 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AAG05928.1 - 0.039 13.8 0.9 0.071 13.0 0.4 1.6 2 0 0 2 2 2 0 Serine hydrolase Methyltransf_25 PF13649.6 AAG05928.1 - 0.065 13.9 0.0 0.18 12.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AAG05928.1 - 0.098 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CDP-OH_P_transf PF01066.21 AAG05929.1 - 1.2e-09 38.8 1.1 1.2e-09 38.8 1.1 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TamB PF04357.13 AAG05930.1 - 4.1e-63 213.9 7.6 1.3e-58 199.1 0.6 4.9 4 1 0 4 4 4 3 TamB, inner membrane protein subunit of TAM complex DUF748 PF05359.11 AAG05930.1 - 1e-05 25.7 3.8 0.079 13.1 0.0 6.0 4 2 1 6 6 6 2 Domain of Unknown Function (DUF748) AsmA_2 PF13502.6 AAG05930.1 - 0.0019 17.7 24.4 0.82 9.1 5.9 7.1 5 2 2 8 8 8 5 AsmA-like C-terminal region Bac_surface_Ag PF01103.23 AAG05931.1 - 1.9e-32 113.1 0.4 3.3e-32 112.3 0.4 1.4 1 1 0 1 1 1 1 Surface antigen POTRA_TamA_1 PF17243.2 AAG05931.1 - 2.4e-19 69.2 0.9 1.3e-18 66.8 0.1 2.4 2 0 0 2 2 2 1 POTRA domain TamA domain 1 POTRA PF07244.15 AAG05931.1 - 4.3e-18 65.7 0.1 7.8e-09 36.0 0.0 3.3 3 0 0 3 3 3 3 Surface antigen variable number repeat CENP-Q PF13094.6 AAG05931.1 - 0.11 12.7 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Acetyltransf_7 PF13508.7 AAG05932.1 - 5.1e-09 36.4 0.0 9.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG05932.1 - 3e-08 33.6 0.0 7.1e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG05932.1 - 3.9e-08 33.5 0.0 6.1e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AAG05932.1 - 2.7e-05 24.3 0.1 0.015 15.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAG05932.1 - 0.0014 18.8 2.0 0.64 10.2 0.3 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG05932.1 - 0.0018 18.2 0.0 0.0044 17.0 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 AAG05932.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Harakiri PF15196.6 AAG05932.1 - 0.017 15.6 0.4 0.035 14.6 0.4 1.6 1 0 0 1 1 1 0 Activator of apoptosis harakiri Exo_endo_phos PF03372.23 AAG05933.1 - 5e-18 65.5 0.0 8.3e-18 64.8 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyoxalase PF00903.25 AAG05934.1 - 2.5e-13 50.3 0.0 3.4e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG05934.1 - 8.7e-05 22.8 0.0 0.00017 21.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG05934.1 - 0.00099 19.9 0.1 0.0019 19.0 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AAG05934.1 - 0.0088 16.0 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AAG05934.1 - 0.013 15.6 0.1 0.024 14.7 0.1 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain LysR_substrate PF03466.20 AAG05935.1 - 5e-48 163.2 8.4 5e-48 163.2 8.4 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05935.1 - 6.8e-20 70.8 1.8 1.2e-19 70.0 1.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG05935.1 - 0.004 17.0 0.6 0.079 12.9 0.1 2.7 2 0 0 2 2 2 1 MarR family PBP_like_2 PF12849.7 AAG05936.1 - 1.8e-25 90.2 0.0 3.3e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AAG05936.1 - 5.8e-17 61.4 0.0 1.7e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 PBP superfamily domain OmpA PF00691.20 AAG05936.1 - 2.2e-09 37.5 0.0 4.8e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 OmpA family SBP_bac_11 PF13531.6 AAG05936.1 - 1.6e-05 24.7 0.8 3e-05 23.9 0.6 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein Dynein_attach_N PF15867.5 AAG05936.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Dynein attachment factor N-terminus TerC PF03741.16 AAG05937.1 - 1.1e-60 204.4 8.5 1.1e-60 204.4 8.5 1.7 2 0 0 2 2 2 1 Integral membrane protein TerC family TauE PF01925.19 AAG05937.1 - 0.092 12.4 26.2 0.22 11.1 17.8 3.1 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF639 PF04842.12 AAG05937.1 - 0.11 11.9 2.0 5.7 6.3 1.3 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) DUF4191 PF13829.6 AAG05937.1 - 1.2 8.5 9.9 1 8.7 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) CcmD PF04995.14 AAG05937.1 - 3.6 7.8 0.0 3.6 7.8 0.0 3.9 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) Acyl-CoA_dh_1 PF00441.24 AAG05938.1 - 1.5e-32 112.9 1.7 2.1e-32 112.4 1.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05938.1 - 4.1e-20 71.8 0.0 6.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG05938.1 - 3.6e-18 66.3 0.3 6.9e-18 65.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAG05938.1 - 2.3e-09 37.6 0.7 2.3e-09 37.6 0.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG05938.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal LysR_substrate PF03466.20 AAG05939.1 - 6.2e-32 110.7 1.3 7.9e-32 110.3 1.3 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05939.1 - 2.7e-16 59.2 0.0 7.4e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Acyl-CoA_dh_1 PF00441.24 AAG05940.1 - 1.6e-51 174.4 5.3 2.8e-51 173.7 5.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG05940.1 - 1.6e-37 128.6 1.5 2e-37 128.3 0.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAG05940.1 - 8.6e-30 103.8 4.8 1.5e-29 103.0 4.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05940.1 - 6.5e-28 96.8 0.0 3.3e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 AAG05940.1 - 0.0082 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF743 PF05332.11 AAG05940.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF743) Thiolase_N PF00108.23 AAG05941.1 - 1.8e-86 289.7 0.5 2.5e-86 289.2 0.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG05941.1 - 5.9e-41 139.0 0.5 5.9e-41 139.0 0.5 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG05941.1 - 0.023 14.3 12.4 0.026 14.1 1.3 3.9 2 2 2 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AAG05941.1 - 0.036 13.9 0.5 16 5.4 0.1 3.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 AAG05942.1 - 2.7e-49 167.3 2.6 3.2e-49 167.0 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG05942.1 - 9.2e-44 149.7 1.9 1.2e-43 149.4 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG05942.1 - 4.1e-11 43.1 4.8 8e-11 42.2 4.8 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG05942.1 - 0.0066 15.9 0.5 0.013 15.0 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 AAG05943.1 - 2.6e-75 253.6 0.0 7.2e-75 252.2 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG05943.1 - 1.9e-24 86.4 0.6 1.3e-23 83.7 0.2 2.4 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Arabinose_bd PF12625.7 AAG05944.1 - 3.6e-45 154.4 1.6 5.7e-45 153.7 1.6 1.3 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG05944.1 - 2.5e-15 56.5 0.4 5.7e-15 55.3 0.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG05944.1 - 5.2e-09 36.0 0.1 2.8e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family SurA_N PF09312.11 AAG05944.1 - 0.0016 18.5 0.0 0.0079 16.3 0.0 1.9 2 0 0 2 2 2 1 SurA N-terminal domain AMP-binding PF00501.28 AAG05945.1 - 6.6e-104 347.8 0.0 7.9e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG05945.1 - 6.4e-18 65.5 0.0 1.7e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MgtC PF02308.16 AAG05946.1 - 7e-33 113.6 14.3 1e-32 113.1 14.3 1.2 1 0 0 1 1 1 1 MgtC family DUF4946 PF16304.5 AAG05947.1 - 6e-65 217.6 0.1 7.1e-65 217.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4946) DUF4351 PF14261.6 AAG05948.1 - 0.0098 15.9 1.6 1.5 9.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4351) PAXX PF15384.6 AAG05948.1 - 0.13 12.0 0.3 0.15 11.7 0.3 1.1 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 MCPsignal PF00015.21 AAG05949.1 - 9.4e-46 155.8 31.5 8.7e-45 152.6 24.9 2.9 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAG05949.1 - 6.6e-10 39.2 0.4 6.6e-10 39.2 0.4 4.9 5 2 1 6 6 6 1 HAMP domain Fib_alpha PF08702.10 AAG05949.1 - 0.0052 17.0 10.6 0.5 10.6 3.7 3.4 3 0 0 3 3 3 2 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 AAG05949.1 - 0.019 15.0 14.2 0.54 10.3 2.2 3.5 2 1 1 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.9 AAG05949.1 - 0.086 13.1 7.5 14 6.0 1.4 4.0 2 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 AAG05949.1 - 0.15 12.1 12.7 0.62 10.1 2.1 3.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Focal_AT PF03623.13 AAG05949.1 - 0.18 11.8 2.1 7.1 6.6 0.0 3.4 3 1 0 3 3 3 0 Focal adhesion targeting region Mce4_CUP1 PF11887.8 AAG05949.1 - 0.39 10.1 9.5 0.22 10.9 3.1 2.7 2 2 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative YabA PF06156.13 AAG05949.1 - 0.96 10.1 7.7 8.5 7.1 0.7 4.2 5 0 0 5 5 5 0 Initiation control protein YabA AIP3 PF03915.13 AAG05949.1 - 3.2 6.8 18.6 0.15 11.2 5.9 2.8 2 1 1 3 3 3 0 Actin interacting protein 3 AAA_13 PF13166.6 AAG05949.1 - 4.1 5.9 11.2 0.49 9.0 3.6 2.1 1 1 1 2 2 2 0 AAA domain Syntaxin_2 PF14523.6 AAG05949.1 - 5 7.6 11.4 2 8.8 1.5 4.1 2 1 1 4 4 3 0 Syntaxin-like protein DUF745 PF05335.13 AAG05949.1 - 8.5 6.1 31.3 5.8 6.6 19.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF745) RcnB PF11776.8 AAG05950.1 - 1.7e-06 28.0 0.1 3.4e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Nickel/cobalt transporter regulator Sulfate_transp PF00916.20 AAG05951.1 - 8.6e-56 189.3 26.0 7.7e-29 100.6 1.6 2.5 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 AAG05951.1 - 1.1e-06 28.3 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 AAG05951.1 - 0.00032 21.1 6.8 0.00032 21.1 6.8 4.0 3 1 0 4 4 4 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 AAG05951.1 - 0.013 15.9 2.3 0.036 14.4 2.3 1.8 1 0 0 1 1 1 0 STAS domain Methyltransf_25 PF13649.6 AAG05952.1 - 1.2e-10 41.9 0.0 2.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG05952.1 - 6.9e-09 36.2 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG05952.1 - 1.7e-08 34.4 0.0 2.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG05952.1 - 1.5e-07 31.4 0.0 4.1e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG05952.1 - 3.5e-07 30.9 0.0 1e-06 29.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAG05952.1 - 0.0006 19.4 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF1641 PF07849.11 AAG05953.1 - 2.6e-09 36.8 0.9 2.6e-09 36.8 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1641) Pyr_redox_2 PF07992.14 AAG05954.1 - 4.5e-10 39.2 0.0 1.3e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG05954.1 - 0.19 12.3 0.0 1.8 9.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EAL PF00563.20 AAG05955.1 - 1.4e-69 234.2 0.0 2.2e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 EAL domain GAF PF01590.26 AAG05955.1 - 5.8e-08 33.4 0.0 1.2e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain GGDEF PF00990.21 AAG05955.1 - 2.4e-06 27.4 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Anophelin PF10731.9 AAG05956.1 - 0.38 10.6 0.2 0.38 10.6 0.2 1.9 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito ATP_synt_H PF05493.13 AAG05956.1 - 8.8 6.9 8.7 1.7 9.2 4.5 2.0 1 1 1 2 2 2 0 ATP synthase subunit H PA-IL PF07828.12 AAG05958.1 - 1.3e-71 238.3 2.6 1.4e-71 238.1 2.6 1.0 1 0 0 1 1 1 1 PA-IL-like protein HATPase_c PF02518.26 AAG05959.1 - 1.3e-23 83.6 0.0 2.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG05959.1 - 1.2e-10 41.3 1.7 1.3e-09 37.9 1.7 2.5 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain COG5 PF10392.9 AAG05959.1 - 0.016 15.4 1.4 0.57 10.4 1.4 2.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 HATPase_c_3 PF13589.6 AAG05959.1 - 0.033 14.0 0.0 0.086 12.7 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rsd_AlgQ PF04353.13 AAG05959.1 - 0.12 12.3 2.2 0.59 10.1 0.1 2.6 2 1 2 4 4 4 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Laminin_II PF06009.12 AAG05959.1 - 0.13 12.3 1.0 0.3 11.1 0.9 1.7 1 1 0 1 1 1 0 Laminin Domain II SPATA1_C PF15743.5 AAG05959.1 - 0.13 12.3 6.5 0.073 13.1 1.3 2.5 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus Baculo_PEP_C PF04513.12 AAG05959.1 - 0.17 11.9 0.5 0.43 10.6 0.2 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HATPase_c_2 PF13581.6 AAG05959.1 - 0.2 11.6 1.1 0.66 9.9 0.0 2.4 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain DUF1840 PF08895.11 AAG05959.1 - 0.2 12.0 1.2 7.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) CorA PF01544.18 AAG05959.1 - 0.27 10.5 5.6 0.41 9.9 1.7 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein COG2 PF06148.11 AAG05959.1 - 3 7.9 4.6 3.4 7.8 1.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_TATA_bd PF12325.8 AAG05959.1 - 5.3 7.3 9.8 3.4 7.9 6.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Response_reg PF00072.24 AAG05960.1 - 1.9e-25 89.2 0.2 4e-25 88.2 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain HD_5 PF13487.6 AAG05960.1 - 2.2e-17 63.1 0.3 2.2e-17 63.1 0.3 2.2 3 0 0 3 3 3 1 HD domain HD PF01966.22 AAG05960.1 - 1.7e-05 25.0 0.0 4.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 HD domain NBP1 PF08537.10 AAG05960.1 - 0.52 9.7 5.0 0.78 9.1 5.0 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 TBD PF12845.7 AAG05960.1 - 3.4 7.6 5.8 3.5 7.6 2.9 2.3 1 1 1 2 2 2 0 TBD domain MCPsignal PF00015.21 AAG05961.1 - 3.1e-47 160.6 23.7 3.1e-47 160.6 23.7 3.3 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAG05961.1 - 3.5e-13 49.7 0.9 3.5e-13 49.7 0.9 5.0 5 1 0 5 5 5 1 HAMP domain 4HB_MCP_1 PF12729.7 AAG05961.1 - 0.00082 19.0 5.0 0.2 11.2 0.0 4.3 5 0 0 5 5 5 1 Four helix bundle sensory module for signal transduction DUF948 PF06103.11 AAG05961.1 - 0.0015 18.8 17.9 3.6 7.9 1.9 6.0 2 1 2 5 5 5 2 Bacterial protein of unknown function (DUF948) Nup88 PF10168.9 AAG05961.1 - 0.037 11.9 10.9 0.1 10.4 0.9 2.2 2 0 0 2 2 2 0 Nuclear pore component AIP3 PF03915.13 AAG05961.1 - 0.039 13.1 9.0 0.069 12.2 9.0 1.4 1 0 0 1 1 1 0 Actin interacting protein 3 KIP1 PF07765.12 AAG05961.1 - 0.041 14.0 3.6 0.096 12.8 0.2 3.2 3 1 0 3 3 3 0 KIP1-like protein ESM4 PF15952.5 AAG05961.1 - 0.4 11.1 5.9 0.075 13.5 1.4 2.1 2 0 0 2 2 2 0 Enhancer of split M4 family FAD-SLDH PF12318.8 AAG05961.1 - 0.77 9.8 0.0 0.77 9.8 0.0 3.3 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase RasGAP_C PF03836.15 AAG05961.1 - 1 9.5 5.8 80 3.4 0.5 4.6 4 2 1 5 5 5 0 RasGAP C-terminus Laminin_II PF06009.12 AAG05961.1 - 2.9 7.9 32.5 0.19 11.7 3.3 5.6 4 2 2 6 6 6 0 Laminin Domain II SlyX PF04102.12 AAG05961.1 - 4.8 7.9 12.2 2.8 8.6 2.1 4.3 3 0 0 3 3 3 0 SlyX CorA PF01544.18 AAG05961.1 - 6 6.1 12.5 6.7 5.9 2.3 3.0 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein APG17 PF04108.12 AAG05961.1 - 6.3 5.8 19.3 2.8 7.0 5.3 3.1 1 1 0 2 2 2 0 Autophagy protein Apg17 TMPIT PF07851.13 AAG05961.1 - 8 5.6 10.9 3.5 6.8 1.5 2.6 2 1 0 2 2 2 0 TMPIT-like protein FA_desaturase PF00487.24 AAG05962.1 - 1.4e-27 97.2 22.5 1.4e-27 97.2 22.5 2.5 1 1 1 3 3 3 1 Fatty acid desaturase TctB PF07331.11 AAG05962.1 - 0.017 15.4 15.3 0.36 11.1 0.2 2.7 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family PIG-Y PF15159.6 AAG05962.1 - 2.2 9.2 13.9 2 9.4 2.1 3.6 2 1 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Nitroreductase PF00881.24 AAG05963.1 - 1.8e-20 73.7 0.2 2e-20 73.5 0.2 1.0 1 0 0 1 1 1 1 Nitroreductase family EamA PF00892.20 AAG05964.1 - 1.1e-26 93.6 36.5 1.3e-17 64.3 15.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 AAG05964.1 - 3.2 8.5 14.8 0.29 11.8 1.5 3.4 2 1 1 3 3 3 0 Small Multidrug Resistance protein AsnC_trans_reg PF01037.21 AAG05965.1 - 6.2e-16 58.1 0.1 1.2e-15 57.3 0.0 1.5 2 0 0 2 2 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAG05965.1 - 4.3e-14 51.8 0.6 9.6e-14 50.7 0.3 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAG05965.1 - 3.2e-13 49.3 2.5 3.9e-13 49.0 1.4 1.7 2 0 0 2 2 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAG05965.1 - 5.7e-05 22.9 0.5 0.00028 20.7 0.2 2.0 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 AAG05965.1 - 9.2e-05 22.2 0.3 0.00019 21.1 0.3 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 AAG05965.1 - 0.00011 22.1 0.0 0.00032 20.6 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAG05965.1 - 0.00072 19.6 0.2 0.0016 18.5 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG05965.1 - 0.00085 19.3 0.1 0.0022 18.0 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HemN_C PF06969.16 AAG05965.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 HemN C-terminal domain GntR PF00392.21 AAG05965.1 - 0.0029 17.2 0.3 0.0052 16.4 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 AAG05965.1 - 0.0082 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DprA_WH PF17782.1 AAG05965.1 - 0.024 14.7 0.2 0.052 13.7 0.2 1.5 1 0 0 1 1 1 0 DprA winged helix domain HTH_10 PF04967.12 AAG05965.1 - 0.037 13.8 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_5 PF01022.20 AAG05965.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 AAG05965.1 - 0.064 13.8 0.1 0.17 12.4 0.1 1.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 AAG05965.1 - 0.079 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HTH_47 PF16221.5 AAG05965.1 - 0.08 12.5 0.2 0.15 11.6 0.1 1.6 2 0 0 2 2 1 0 winged helix-turn-helix HTH_26 PF13443.6 AAG05965.1 - 0.087 13.3 0.1 0.22 12.0 0.1 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Fe_dep_repress PF01325.19 AAG05965.1 - 0.09 13.0 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HxlR PF01638.17 AAG05965.1 - 0.094 12.6 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 HxlR-like helix-turn-helix M11L PF11099.8 AAG05965.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.6 2 0 0 2 2 2 0 Apoptosis regulator M11L like HTH_9 PF08221.11 AAG05965.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_36 PF13730.6 AAG05965.1 - 0.19 11.7 0.1 0.94 9.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Acetyltransf_1 PF00583.25 AAG05966.1 - 9.4e-17 61.3 0.0 1.2e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAG05966.1 - 4.9e-14 53.2 0.0 5.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG05966.1 - 3.7e-09 36.6 0.0 4.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG05966.1 - 7.3e-08 32.7 0.0 1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG05966.1 - 1.7e-06 27.8 0.5 2.2e-05 24.2 0.5 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG05966.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AAG05966.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AAG05966.1 - 0.026 14.7 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Trp_dioxygenase PF03301.13 AAG05967.1 - 5.6e-69 233.1 1.4 3.1e-42 145.2 0.2 2.5 1 1 1 2 2 2 2 Tryptophan 2,3-dioxygenase TPR_14 PF13428.6 AAG05967.1 - 3.7 8.6 8.6 3.3 8.8 0.2 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Flavodoxin_2 PF02525.17 AAG05968.1 - 3.6e-35 121.5 0.0 4.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold ProQ PF04352.13 AAG05970.1 - 5.1e-32 110.0 0.5 5.1e-32 110.0 0.5 1.6 2 0 0 2 2 2 1 ProQ/FINO family SBP_bac_3 PF00497.20 AAG05971.1 - 6.9e-37 127.0 0.0 2.3e-18 66.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Response_reg PF00072.24 AAG05971.1 - 2.4e-26 92.1 0.0 1.2e-25 89.9 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 AAG05971.1 - 2.1e-24 86.2 0.0 3.8e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG05971.1 - 2.1e-11 43.7 0.2 5.4e-11 42.4 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CDP-OH_P_transf PF01066.21 AAG05972.1 - 7.9e-18 65.0 1.5 7.9e-18 65.0 1.5 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UvrC_HhH_N PF08459.11 AAG05973.1 - 2.9e-53 179.9 0.0 5.6e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal HHH_5 PF14520.6 AAG05973.1 - 1.3e-12 48.1 0.0 3.6e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 AAG05973.1 - 2.3e-10 39.8 0.1 5.4e-05 22.8 0.1 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix motif GIY-YIG PF01541.24 AAG05973.1 - 7.2e-10 39.0 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain HHH_2 PF12826.7 AAG05973.1 - 1.7e-07 31.2 0.0 4.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif UVR PF02151.19 AAG05973.1 - 2.4e-06 27.1 1.0 7.2e-06 25.6 1.0 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_3 PF12836.7 AAG05973.1 - 0.00015 22.0 0.3 0.048 13.9 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AAG05973.1 - 0.014 15.9 0.1 0.055 14.1 0.0 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Lzipper-MIP1 PF14389.6 AAG05973.1 - 0.099 12.9 0.3 0.67 10.3 0.3 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Response_reg PF00072.24 AAG05974.1 - 1.7e-28 99.0 0.1 2.5e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG05974.1 - 5.1e-15 54.8 0.2 1.4e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Homeodomain PF00046.29 AAG05974.1 - 0.098 12.5 0.1 3.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Homeodomain PELOTA_1 PF15608.6 AAG05974.1 - 0.1 12.5 0.2 0.63 10.0 0.1 2.1 2 0 0 2 2 2 0 PELOTA RNA binding domain DUF4152 PF13680.6 AAG05974.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4152) B12-binding PF02310.19 AAG05974.1 - 0.12 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain Sigma70_r4_2 PF08281.12 AAG05974.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 FAD_binding_3 PF01494.19 AAG05975.1 - 9.2e-22 77.7 0.2 2.5e-21 76.3 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAG05975.1 - 9.2e-05 21.7 0.0 0.00022 20.4 0.0 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AAG05975.1 - 0.0018 17.6 0.1 0.19 10.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG05975.1 - 0.0026 18.0 0.1 0.0073 16.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAG05975.1 - 0.022 13.9 0.2 0.041 13.0 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 AAG05975.1 - 0.025 14.1 0.2 0.025 14.1 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAG05975.1 - 0.029 14.9 0.0 0.077 13.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG05975.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 AAG05975.1 - 0.14 11.2 0.0 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase HTH_18 PF12833.7 AAG05976.1 - 1.4e-18 66.9 2.2 2.6e-18 66.1 2.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Arabinose_bd PF12625.7 AAG05976.1 - 2.5e-15 57.0 0.2 2.5e-15 57.0 0.2 1.8 2 1 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_AraC PF00165.23 AAG05976.1 - 5.6e-07 29.5 0.0 3.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 AAG05976.1 - 0.0021 18.1 5.1 0.01 15.9 0.4 3.0 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_DeoR PF08220.12 AAG05976.1 - 0.042 13.6 1.1 2.1 8.2 0.5 2.6 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 AAG05976.1 - 0.058 13.2 6.8 1.7 8.6 0.4 3.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_8 PF02954.19 AAG05976.1 - 0.069 12.9 0.5 0.41 10.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_Tnp_ISL3 PF13542.6 AAG05976.1 - 0.072 12.5 0.1 0.22 11.0 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 GntR PF00392.21 AAG05976.1 - 0.23 11.2 3.0 19 5.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family MFS_1 PF07690.16 AAG05977.1 - 1.6e-38 132.5 50.8 1.6e-38 132.5 50.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TonB_dep_Rec PF00593.24 AAG05978.1 - 1.2e-42 147.4 29.8 1.8e-42 146.8 29.8 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG05978.1 - 6.7e-23 81.3 1.4 1.1e-22 80.6 0.4 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG05978.1 - 7.3e-08 32.1 0.0 2.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain GerE PF00196.19 AAG05979.1 - 5.8e-19 67.4 0.1 8.3e-19 66.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG05979.1 - 1.9e-06 27.4 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG05979.1 - 0.0022 17.5 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG05979.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 ECF sigma factor HTH_23 PF13384.6 AAG05979.1 - 0.018 14.8 0.1 0.044 13.6 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Trp_repressor PF01371.19 AAG05979.1 - 0.082 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein SBP_bac_8 PF13416.6 AAG05980.1 - 2.5e-26 93.1 0.0 3.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG05980.1 - 3.4e-19 69.2 0.0 5.7e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG05980.1 - 2.3e-13 50.8 0.0 9.4e-13 48.8 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG05980.1 - 4e-07 30.0 0.0 7.9e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein NMT1 PF09084.11 AAG05982.1 - 1.9e-15 57.4 0.0 2.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAG05982.1 - 6e-14 52.3 0.0 1.3e-13 51.2 0.0 1.5 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAG05982.1 - 3.4e-08 33.2 0.0 7.9e-08 32.0 0.0 1.6 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 AAG05982.1 - 1e-07 31.8 0.1 4.6e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 AAG05982.1 - 7e-05 22.4 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAG05982.1 - 0.00052 19.7 1.4 0.0012 18.5 1.4 1.7 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein ScsC_N PF18312.1 AAG05982.1 - 0.026 14.3 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain FaeA PF04703.12 AAG05982.1 - 0.26 11.7 1.5 8.1 6.9 0.6 2.6 2 0 0 2 2 2 0 FaeA-like protein NMT1 PF09084.11 AAG05983.1 - 6e-11 42.7 0.0 7.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAG05983.1 - 9.5e-11 41.9 0.3 1.5e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAG05983.1 - 5.1e-09 36.1 0.4 6.8e-09 35.7 0.4 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAG05983.1 - 3.2e-08 33.3 0.0 2.9e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AAG05983.1 - 6.2e-06 25.8 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAG05984.1 - 3.3e-18 66.4 0.0 5.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAG05984.1 - 2.1e-09 37.5 0.0 3.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAG05984.1 - 2e-07 30.9 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 AAG05984.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAG05984.1 - 0.00068 19.1 0.0 0.017 14.5 0.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 AAG05984.1 - 0.042 13.4 0.0 0.087 12.4 0.0 1.5 1 1 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Acyl-CoA_dh_2 PF08028.11 AAG05985.1 - 3.2e-10 40.4 0.0 3.9e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG05985.1 - 1.7e-09 37.7 0.0 4.6e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 AAG05985.1 - 2.8e-06 27.6 0.0 6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG05985.1 - 0.00011 22.8 0.0 0.00025 21.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Bac_luciferase PF00296.20 AAG05986.1 - 9.4e-77 258.5 8.5 1.3e-76 258.1 8.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NMT1 PF09084.11 AAG05987.1 - 5e-17 62.6 0.0 9.2e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAG05987.1 - 9.8e-15 54.9 0.1 1.4e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAG05987.1 - 4.3e-09 36.3 0.0 2e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein OpuAC PF04069.12 AAG05987.1 - 6.1e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 AAG05987.1 - 5.9e-05 22.6 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Bac_luciferase PF00296.20 AAG05988.1 - 4e-75 253.1 14.1 4.5e-75 253.0 14.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pan_kinase PF03309.14 AAG05988.1 - 0.094 12.5 0.1 0.26 11.1 0.1 1.7 2 0 0 2 2 2 0 Type III pantothenate kinase DUF1320 PF07030.12 AAG05988.1 - 0.11 12.6 0.4 1.1 9.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1320) LysR_substrate PF03466.20 AAG05989.1 - 2.4e-36 125.1 7.5 3.4e-36 124.6 7.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG05989.1 - 2.5e-18 65.7 0.6 6.3e-18 64.5 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG05989.1 - 0.0047 16.8 0.2 0.017 15.0 0.2 1.9 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAG05989.1 - 0.0064 16.0 0.3 0.016 14.8 0.3 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 AAG05989.1 - 0.0081 15.9 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_AsnC-type PF13404.6 AAG05989.1 - 0.0095 15.7 0.2 0.039 13.8 0.2 2.1 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 AAG05989.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_50 PF18024.1 AAG05989.1 - 0.064 12.9 0.2 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 AAG05989.1 - 0.1 12.4 1.8 0.19 11.5 0.3 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR PF01047.22 AAG05989.1 - 0.16 11.9 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 MarR family CDO_I PF05995.12 AAG05990.1 - 4.9e-08 32.5 0.0 6.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 AAG05990.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.4 2 0 0 2 2 2 0 PCO_ADO Rhodanese PF00581.20 AAG05991.1 - 2.9e-43 146.7 0.0 4.6e-09 36.7 0.0 4.2 4 0 0 4 4 4 4 Rhodanese-like domain Bax1-I PF01027.20 AAG05992.1 - 2.8e-44 151.4 35.3 3.2e-44 151.3 35.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CcmD PF04995.14 AAG05992.1 - 0.27 11.4 0.2 0.27 11.4 0.2 2.9 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) DrsE PF02635.15 AAG05993.1 - 3.9e-24 85.3 0.0 4.3e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DMRL_synthase PF00885.19 AAG05993.1 - 0.035 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase DrsE PF02635.15 AAG05994.1 - 2e-20 73.3 0.0 2.2e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DsrH PF04077.12 AAG05995.1 - 1.3e-23 82.9 0.0 1.5e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 DsrH like protein DsrC PF04358.13 AAG05996.1 - 7.2e-36 123.0 0.0 8e-36 122.8 0.0 1.0 1 0 0 1 1 1 1 DsrC like protein RP-C PF03428.13 AAG05996.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain Glycos_trans_3N PF02885.17 AAG05997.1 - 9.1e-18 63.9 0.9 3e-17 62.2 0.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.21 AAG05997.1 - 1.9e-05 24.4 0.0 3.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain GST_N_2 PF13409.6 AAG05998.1 - 4.8e-22 78.0 0.0 1.4e-21 76.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAG05998.1 - 4.1e-14 52.3 0.5 1.3e-13 50.7 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAG05998.1 - 1.1e-10 41.6 0.0 2.2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG05998.1 - 2.6e-05 24.3 0.0 5.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AAG05998.1 - 0.00096 19.5 0.0 0.01 16.2 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 AAG05998.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TP_methylase PF00590.20 AAG05999.1 - 1.9e-55 188.1 1.1 1.2e-54 185.5 0.2 2.1 1 1 1 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 AAG05999.1 - 1.6e-28 99.2 0.0 5.5e-28 97.4 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 AAG05999.1 - 1.6e-22 78.9 2.9 5.6e-22 77.2 2.9 2.0 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region Sirohm_synth_M PF14824.6 AAG05999.1 - 8.7e-08 31.5 0.1 2.2e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Radical_SAM PF04055.21 AAG05999.1 - 0.075 13.4 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 Radical SAM superfamily tRNA-synt_2b PF00587.25 AAG06000.1 - 3.3e-36 124.9 0.0 4.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AAG06000.1 - 7.1e-31 106.6 0.6 1.1e-30 106.1 0.6 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FmiP_Thoc5 PF09766.9 AAG06000.1 - 0.042 13.1 1.4 0.06 12.6 1.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 BLOC1_2 PF10046.9 AAG06000.1 - 0.12 12.7 0.2 0.31 11.4 0.2 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MgsA_C PF12002.8 AAG06001.1 - 8.1e-68 227.6 0.0 1.3e-67 226.9 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 AAG06001.1 - 8.2e-22 77.3 0.0 2.6e-20 72.5 0.0 2.6 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 AAG06001.1 - 1.4e-15 57.9 0.0 2.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAG06001.1 - 5.1e-15 55.6 0.0 8.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AAG06001.1 - 6.3e-07 29.5 0.0 3.4e-06 27.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAG06001.1 - 8.9e-07 29.4 1.1 0.00089 19.7 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 AAG06001.1 - 1e-05 25.0 0.1 0.0028 17.0 0.1 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAG06001.1 - 1.8e-05 24.9 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG06001.1 - 2.3e-05 24.7 0.6 0.02 15.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain Sigma54_activat PF00158.26 AAG06001.1 - 0.00011 22.0 0.0 0.062 13.0 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.14 AAG06001.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 AAG06001.1 - 0.00063 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAG06001.1 - 0.00092 19.8 0.0 0.0089 16.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAG06001.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 AAG06001.1 - 0.0012 18.6 0.0 0.018 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAG06001.1 - 0.0012 18.8 0.0 0.67 9.8 0.0 2.6 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 AAG06001.1 - 0.0013 19.1 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase ResIII PF04851.15 AAG06001.1 - 0.0024 17.9 0.1 0.19 11.7 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 AAG06001.1 - 0.0038 17.1 0.0 0.0074 16.2 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase AAA_3 PF07726.11 AAG06001.1 - 0.0064 16.4 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AAG06001.1 - 0.0092 16.5 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DNA_pol3_delta2 PF13177.6 AAG06001.1 - 0.01 15.6 0.0 4.4 7.0 0.0 2.2 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_28 PF13521.6 AAG06001.1 - 0.013 15.7 0.0 0.038 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAG06001.1 - 0.023 15.1 0.1 6 7.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 AAG06001.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 AAG06001.1 - 0.028 14.5 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 AAG06001.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 AAG06001.1 - 0.14 12.5 0.0 0.46 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 AAG06001.1 - 0.19 11.2 0.1 7.9 5.8 0.0 2.7 1 1 2 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 AAG06001.1 - 0.19 11.3 0.0 0.6 9.6 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 AAG06001.1 - 0.24 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain LolA PF03548.15 AAG06002.1 - 6e-57 191.9 0.9 6.9e-57 191.7 0.9 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA DUF2092 PF09865.9 AAG06002.1 - 0.0019 17.6 0.0 0.082 12.2 0.0 2.2 2 0 0 2 2 2 1 Predicted periplasmic protein (DUF2092) LolA_like PF17131.4 AAG06002.1 - 0.082 12.6 0.4 7 6.4 0.0 2.2 1 1 0 2 2 2 0 Outer membrane lipoprotein-sorting protein BBS2_N PF14781.6 AAG06002.1 - 0.082 12.8 0.0 2 8.4 0.0 2.4 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal FtsK_SpoIIIE PF01580.18 AAG06003.1 - 1.1e-63 214.9 0.1 3.9e-63 213.1 0.1 1.9 1 1 0 1 1 1 1 FtsK/SpoIIIE family FtsK_4TM PF13491.6 AAG06003.1 - 1.6e-39 135.4 15.6 2.4e-39 134.8 15.6 1.2 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE FtsK_alpha PF17854.1 AAG06003.1 - 3.5e-32 110.6 0.2 6.8e-32 109.6 0.2 1.5 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 AAG06003.1 - 1e-26 92.5 0.1 1.9e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Ftsk gamma domain AAA_10 PF12846.7 AAG06003.1 - 3.9e-06 26.0 0.0 0.0019 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.17 AAG06003.1 - 7.7e-05 22.9 0.7 0.00037 20.7 0.2 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 AAG06003.1 - 0.0048 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein FliT PF05400.13 AAG06003.1 - 0.025 15.4 5.5 0.05 14.4 3.4 2.5 2 0 0 2 2 2 0 Flagellar protein FliT TrwB_AAD_bind PF10412.9 AAG06003.1 - 0.026 13.4 0.1 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Cupin_4 PF08007.12 AAG06003.1 - 0.14 11.6 0.3 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein AAA_22 PF13401.6 AAG06003.1 - 0.18 12.1 0.0 20 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain CCDC50_N PF15295.6 AAG06003.1 - 0.24 11.6 1.5 0.43 10.8 1.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus MFS_MOT1 PF16983.5 AAG06003.1 - 3.3 8.1 6.2 1.2 9.5 2.9 1.9 2 0 0 2 2 1 0 Molybdate transporter of MFS superfamily Pyr_redox_2 PF07992.14 AAG06004.1 - 4.8e-49 167.2 1.2 5.5e-49 167.0 1.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG06004.1 - 1.4e-19 70.4 1.5 1.3e-18 67.3 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG06004.1 - 6.8e-18 65.0 0.1 3e-14 53.0 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG06004.1 - 1.9e-05 23.9 7.0 0.0014 17.8 0.2 3.6 1 1 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 AAG06004.1 - 9.7e-05 21.9 0.2 0.0018 17.7 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG06004.1 - 0.00012 20.9 0.9 0.46 9.1 0.1 3.6 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 AAG06004.1 - 0.00013 22.1 0.1 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AAG06004.1 - 0.00018 20.7 3.8 0.085 11.9 0.1 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A Thi4 PF01946.17 AAG06004.1 - 0.0016 17.7 0.1 0.012 14.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 AAG06004.1 - 0.0093 15.6 3.3 12 5.3 0.4 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAG06004.1 - 0.012 16.0 0.0 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Hema_HEFG PF02710.14 AAG06004.1 - 0.027 14.7 0.3 0.047 13.9 0.3 1.3 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein K_oxygenase PF13434.6 AAG06004.1 - 0.076 12.1 0.0 0.41 9.7 0.0 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Leu_Phe_trans PF03588.14 AAG06005.1 - 1e-75 252.9 0.0 1.2e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Pertussis_S2S3 PF02918.15 AAG06005.1 - 0.039 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain ATE_C PF04377.15 AAG06006.1 - 1.1e-40 139.4 0.2 1.7e-40 138.7 0.2 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 AAG06006.1 - 4.2e-19 68.7 0.1 7.6e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 AAG06006.1 - 2.2e-06 27.9 0.3 3.2e-06 27.3 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain eIF-1a PF01176.19 AAG06007.1 - 1.5e-27 95.2 0.1 1.6e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 AAG06007.1 - 2e-05 24.2 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 RsgA N-terminal domain S1 PF00575.23 AAG06007.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain RNase_II_C_S1 PF18614.1 AAG06007.1 - 0.033 14.1 0.1 0.19 11.7 0.1 2.1 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain OB_aCoA_assoc PF01796.17 AAG06007.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated CSD2 PF17876.1 AAG06007.1 - 0.13 12.5 0.0 4.4 7.5 0.0 2.5 1 1 2 3 3 3 0 Cold shock domain AAA_2 PF07724.14 AAG06008.1 - 4.4e-52 176.7 0.1 2.4e-49 167.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAG06008.1 - 1.7e-28 98.6 1.3 4.9e-28 97.1 1.3 1.8 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AAG06008.1 - 4.4e-27 95.1 0.0 6.2e-12 46.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AAG06008.1 - 2.8e-26 91.4 0.3 2.9e-25 88.1 0.1 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AAG06008.1 - 7.6e-20 71.3 0.1 1.4e-14 54.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 AAG06008.1 - 3.2e-16 59.2 3.5 7.8e-16 57.9 1.1 2.9 3 0 0 3 3 2 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 AAG06008.1 - 1.8e-15 57.7 6.2 2.8e-07 31.1 0.2 5.7 5 1 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 AAG06008.1 - 2e-11 44.3 1.6 0.00036 20.8 0.1 4.8 3 3 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 AAG06008.1 - 6.4e-11 42.2 0.1 1e-06 28.5 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 AAG06008.1 - 3.3e-08 33.4 2.6 0.0044 16.8 0.1 4.3 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 AAG06008.1 - 8.7e-08 31.8 0.0 0.00026 20.4 0.0 3.6 2 2 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 AAG06008.1 - 4.9e-07 30.3 0.2 0.0056 17.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 AAG06008.1 - 8.4e-07 28.6 0.1 1.1 8.6 0.0 3.5 2 1 1 3 3 3 3 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 AAG06008.1 - 1e-06 28.8 0.0 0.053 13.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 AAG06008.1 - 1.2e-06 28.2 0.0 0.037 13.5 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 AAG06008.1 - 1.3e-06 28.4 0.0 0.076 13.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAG06008.1 - 5.4e-06 26.6 0.1 0.0015 18.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 AAG06008.1 - 7.6e-06 25.8 0.1 0.00021 21.1 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AAG06008.1 - 7.7e-06 25.8 0.0 0.085 12.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 AAG06008.1 - 2.5e-05 23.7 0.0 0.08 12.1 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_6 PF12774.7 AAG06008.1 - 2.6e-05 23.4 0.0 0.00011 21.3 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region ResIII PF04851.15 AAG06008.1 - 8e-05 22.7 0.0 0.67 9.9 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit NACHT PF05729.12 AAG06008.1 - 9.3e-05 22.4 0.0 0.035 14.0 0.0 2.9 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 AAG06008.1 - 0.00012 22.4 0.0 0.36 11.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 AAG06008.1 - 0.00014 21.3 0.0 0.076 12.3 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 AAG06008.1 - 0.00036 20.5 0.0 0.49 10.3 0.0 3.6 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 AAG06008.1 - 0.0012 18.8 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase DNA_pol3_delta2 PF13177.6 AAG06008.1 - 0.0014 18.5 0.0 0.55 10.0 0.0 3.5 4 0 0 4 4 3 1 DNA polymerase III, delta subunit Torsin PF06309.11 AAG06008.1 - 0.0041 17.2 0.0 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Torsin Rad17 PF03215.15 AAG06008.1 - 0.0048 16.8 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 AAG06008.1 - 0.0076 15.5 0.0 0.51 9.5 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 AAG06008.1 - 0.0087 15.7 0.4 2.1 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.12 AAG06008.1 - 0.016 14.8 0.1 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IPT PF01745.16 AAG06008.1 - 0.016 14.6 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase SRP54 PF00448.22 AAG06008.1 - 0.016 14.8 0.8 7.6 6.1 0.1 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 AAG06008.1 - 0.017 15.4 0.4 1.1 9.5 0.0 3.4 4 0 0 4 4 2 0 AAA domain SKI PF01202.22 AAG06008.1 - 0.02 15.0 0.3 0.16 12.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_24 PF13479.6 AAG06008.1 - 0.032 13.9 0.0 14 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 AAG06008.1 - 0.044 13.5 1.2 3.1 7.5 0.0 3.4 3 1 0 4 4 3 0 AAA domain Cytidylate_kin2 PF13189.6 AAG06008.1 - 0.058 13.5 0.1 2.7 8.1 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase-like family T2SSE PF00437.20 AAG06008.1 - 0.061 12.4 0.0 3.5 6.6 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein DUF815 PF05673.13 AAG06008.1 - 0.073 12.2 0.2 2.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 AAG06008.1 - 0.081 12.8 0.2 12 5.7 0.0 3.5 4 0 0 4 4 3 0 NTPase AAA_29 PF13555.6 AAG06008.1 - 0.084 12.6 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 AAG06008.1 - 0.086 13.1 0.0 3.8 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase dNK PF01712.19 AAG06008.1 - 0.13 12.1 0.0 0.84 9.4 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase FliG_N PF14842.6 AAG06008.1 - 1.4 9.5 3.8 8.7 6.9 0.0 3.8 4 0 0 4 4 3 0 FliG N-terminal domain ClpS PF02617.17 AAG06009.1 - 3.4e-31 106.9 0.4 3.7e-31 106.7 0.4 1.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CSD PF00313.22 AAG06010.1 - 4.1e-27 93.8 0.0 5e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAG06010.1 - 0.043 13.5 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease B OB domain Iso_dh PF00180.20 AAG06011.1 - 8.6e-118 393.4 0.0 1e-117 393.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase G-patch_2 PF12656.7 AAG06011.1 - 0.0054 16.8 1.4 6.4 6.9 0.0 4.1 4 0 0 4 4 4 2 G-patch domain tRNA_synt_1c_R1 PF04558.15 AAG06011.1 - 0.13 12.2 0.5 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 IDH PF03971.14 AAG06012.1 - 0 1285.6 0.1 0 1285.4 0.1 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase NUDIX PF00293.28 AAG06013.1 - 1.2e-16 60.9 0.6 1.4e-16 60.7 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain EnY2 PF10163.9 AAG06013.1 - 0.16 12.3 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcription factor e(y)2 tRNA_Me_trans PF03054.16 AAG06014.1 - 1.6e-136 454.8 0.0 1.8e-136 454.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 AAG06014.1 - 7e-06 25.3 0.0 2.3e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 AAG06014.1 - 7.5e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 AAG06014.1 - 0.0061 16.1 0.0 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AAG06014.1 - 0.0078 16.0 0.0 0.022 14.5 0.0 1.9 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 AAG06014.1 - 0.023 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase DUF489 PF04356.12 AAG06015.1 - 6.8e-71 238.3 1.2 7.7e-71 238.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) Ald_deCOase PF11266.8 AAG06015.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase EamA PF00892.20 AAG06016.1 - 1.9e-30 105.8 29.1 9.1e-20 71.2 7.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family SDH_alpha PF03313.15 AAG06016.1 - 0.04 13.6 0.5 0.04 13.6 0.5 1.5 2 0 0 2 2 2 0 Serine dehydratase alpha chain Lyase_1 PF00206.20 AAG06017.1 - 4.4e-66 223.4 0.0 6.2e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 AAG06017.1 - 8.7e-51 170.9 0.1 2.9e-50 169.2 0.0 1.9 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal Cupin_4 PF08007.12 AAG06018.1 - 1.7e-106 356.3 0.1 2e-106 356.1 0.1 1.1 1 0 0 1 1 1 1 Cupin superfamily protein AraC_binding PF02311.19 AAG06018.1 - 0.00019 21.3 0.2 0.00049 20.0 0.2 1.7 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 AAG06018.1 - 0.00091 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Asp_Arg_Hydrox PF05118.15 AAG06018.1 - 0.045 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase Cupin_8 PF13621.6 AAG06018.1 - 0.069 12.8 0.3 0.56 9.9 0.5 2.3 2 1 0 2 2 2 0 Cupin-like domain Cupin_2 PF07883.11 AAG06018.1 - 0.089 12.5 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Acetyltransf_10 PF13673.7 AAG06019.1 - 5e-23 81.4 0.0 5.4e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG06019.1 - 1.5e-13 51.0 0.2 1.8e-13 50.8 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG06019.1 - 2.3e-12 47.2 0.1 3.3e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAG06019.1 - 3.5e-06 27.1 0.1 1e-05 25.6 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 AAG06019.1 - 0.00072 20.2 0.0 0.0069 17.1 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG06019.1 - 0.0063 16.4 0.1 0.0099 15.8 0.1 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AAG06019.1 - 0.056 13.6 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Secretin_N PF03958.17 AAG06021.1 - 3.4e-10 40.2 0.2 3.4e-10 40.2 0.2 2.0 2 1 0 2 2 2 1 Bacterial type II/III secretion system short domain Secretin PF00263.21 AAG06021.1 - 1.5e-07 31.3 1.4 1.5e-07 31.3 1.4 1.8 2 0 0 2 2 2 1 Bacterial type II and III secretion system protein ICL PF00463.21 AAG06022.1 - 6.8e-47 160.1 2.0 3.5e-20 72.0 0.1 3.1 3 0 0 3 3 3 3 Isocitrate lyase family PEP_mutase PF13714.6 AAG06022.1 - 2.9e-12 46.6 0.4 5.7e-12 45.6 0.4 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF839 PF05787.13 AAG06023.1 - 4.6e-196 653.0 0.0 5.3e-196 652.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) TAT_signal PF10518.9 AAG06023.1 - 0.042 13.7 7.0 0.091 12.6 7.0 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF4442 PF14539.6 AAG06024.1 - 5.6e-33 113.9 0.0 6.7e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Oxidored_q4 PF00507.19 AAG06025.1 - 8.7e-34 115.6 0.6 1.1e-33 115.3 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K_trans PF02705.16 AAG06025.1 - 0.025 13.1 0.3 0.031 12.8 0.3 1.1 1 0 0 1 1 1 0 K+ potassium transporter Oxidored_q6 PF01058.22 AAG06026.1 - 7.2e-22 77.6 0.1 1.2e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_49kDa PF00346.19 AAG06027.1 - 6.4e-107 356.7 0.0 8.5e-107 356.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Complex1_30kDa PF00329.19 AAG06027.1 - 1e-41 142.4 0.1 2.5e-41 141.1 0.1 1.7 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 2Fe-2S_thioredx PF01257.19 AAG06028.1 - 8.5e-50 168.4 0.0 9.7e-50 168.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Complex1_51K PF01512.17 AAG06029.1 - 1e-51 174.8 0.0 1.4e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AAG06029.1 - 1.6e-24 85.7 0.0 2.9e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AAG06029.1 - 5.4e-05 23.0 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 SLBB domain NADH-G_4Fe-4S_3 PF10588.9 AAG06030.1 - 4.8e-15 54.8 0.7 1.1e-14 53.7 0.7 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Molybdop_Fe4S4 PF04879.16 AAG06030.1 - 1.4e-12 47.4 0.3 3.8e-12 46.0 0.3 1.8 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Molybdopterin PF00384.22 AAG06030.1 - 1.9e-12 46.9 0.0 1.2e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 AAG06030.1 - 1e-10 41.5 0.1 3e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AAG06030.1 - 4.4e-10 39.4 1.8 5.9e-10 39.0 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molydop_binding PF01568.21 AAG06030.1 - 0.11 12.5 0.0 0.49 10.5 0.0 2.1 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Fer4_6 PF12837.7 AAG06030.1 - 1.1 9.4 8.4 0.18 11.9 0.7 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain NADHdh PF00146.21 AAG06031.1 - 9.7e-115 383.0 18.2 1.1e-114 382.7 18.2 1.0 1 0 0 1 1 1 1 NADH dehydrogenase DUF2976 PF11190.8 AAG06031.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) Fer4 PF00037.27 AAG06032.1 - 2.1e-14 52.6 16.6 7.1e-09 35.1 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAG06032.1 - 8.6e-12 45.5 10.6 1.4e-11 44.8 10.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAG06032.1 - 3.6e-10 39.8 8.3 5.4e-05 23.2 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG06032.1 - 5.9e-10 39.9 6.1 0.00016 22.5 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AAG06032.1 - 1.2e-09 38.1 18.6 1.7e-06 28.0 11.7 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG06032.1 - 1.8e-08 34.7 1.6 0.0021 18.5 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG06032.1 - 1.1e-07 31.9 10.4 4.6e-07 29.9 10.9 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG06032.1 - 1.5e-06 28.6 5.1 0.0093 16.5 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAG06032.1 - 4.4e-06 26.5 12.4 0.011 15.8 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAG06032.1 - 3e-05 23.9 16.9 0.0047 16.9 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAG06032.1 - 0.0011 19.3 13.4 0.07 13.7 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAG06032.1 - 0.0057 16.8 4.7 0.57 10.4 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAG06032.1 - 0.0081 16.7 10.5 0.61 10.7 1.7 2.7 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AAG06032.1 - 0.0089 16.9 3.6 0.0089 16.9 3.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain ETF_QO PF05187.13 AAG06032.1 - 0.12 12.5 5.3 0.31 11.2 2.3 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 AAG06032.1 - 0.94 10.4 14.6 3.3 8.6 2.4 2.2 1 1 0 2 2 2 0 4Fe-4S dicluster domain Oxidored_q3 PF00499.20 AAG06033.1 - 5.8e-33 113.6 16.4 7.1e-33 113.3 16.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PalH PF08733.10 AAG06033.1 - 0.25 10.3 2.0 0.35 9.8 0.2 2.0 1 1 1 2 2 2 0 PalH/RIM21 ABC2_membrane_3 PF12698.7 AAG06033.1 - 8.6 5.4 13.1 11 5.0 13.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Cadherin_C_2 PF16492.5 AAG06033.1 - 9.6 7.0 8.9 0.84 10.4 2.2 2.6 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Oxidored_q2 PF00420.24 AAG06034.1 - 4e-22 77.8 5.5 4.7e-22 77.6 5.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NAD4L PF06235.11 AAG06034.1 - 0.015 15.3 4.3 0.046 13.7 4.3 1.8 1 1 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) Proton_antipo_M PF00361.20 AAG06035.1 - 1.2e-90 303.7 18.9 1.2e-90 303.7 18.9 2.4 3 0 0 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAG06035.1 - 4.4e-22 77.9 3.0 4.4e-22 77.9 3.0 2.5 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_M PF00361.20 AAG06036.1 - 1.8e-72 244.0 25.0 3.1e-72 243.2 25.0 1.4 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_M PF00361.20 AAG06037.1 - 7.2e-81 271.6 25.0 1.8e-80 270.3 25.0 1.7 1 0 0 1 1 1 1 Proton-conducting membrane transporter Methyltransf_11 PF08241.12 AAG06038.1 - 1.5e-16 60.8 0.0 2.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG06038.1 - 7.2e-13 49.1 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG06038.1 - 2.5e-06 28.2 0.0 4.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG06038.1 - 3.1e-06 27.1 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAG06038.1 - 0.0067 15.8 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AAG06038.1 - 0.066 13.1 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AI-2E_transport PF01594.16 AAG06039.1 - 1.1e-52 179.2 32.8 1.3e-52 179.0 32.8 1.0 1 0 0 1 1 1 1 AI-2E family transporter Bac_rhodopsin PF01036.18 AAG06039.1 - 0.0044 16.6 2.8 0.0044 16.6 2.8 3.4 2 1 1 3 3 3 1 Bacteriorhodopsin-like protein DUF3810 PF12725.7 AAG06039.1 - 1.3 8.3 3.9 0.84 8.9 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) MCPsignal PF00015.21 AAG06040.1 - 5.2e-46 156.6 36.3 5.5e-42 143.5 24.0 2.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain sCache_2 PF17200.4 AAG06040.1 - 3.5e-25 88.7 0.0 3.5e-25 88.7 0.0 4.0 3 2 2 5 5 4 1 Single Cache domain 2 dCache_2 PF08269.11 AAG06040.1 - 1.1e-16 60.9 10.3 1.1e-16 60.9 0.0 3.8 2 2 2 5 5 5 1 Cache domain HAMP PF00672.25 AAG06040.1 - 3.7e-14 52.8 16.8 8.1e-13 48.5 0.1 6.6 7 0 0 7 7 5 1 HAMP domain DUF948 PF06103.11 AAG06040.1 - 1e-05 25.7 22.1 0.42 10.9 1.1 5.2 1 1 1 4 4 4 3 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 AAG06040.1 - 2.2e-05 24.8 5.7 0.31 11.4 0.3 4.0 3 1 0 3 3 3 2 Syntaxin-like protein Laminin_I PF06008.14 AAG06040.1 - 0.0018 18.1 8.0 0.0018 18.1 8.0 2.9 1 1 0 2 2 2 1 Laminin Domain I FPP PF05911.11 AAG06040.1 - 0.0026 16.1 6.9 0.055 11.7 1.6 2.1 2 0 0 2 2 2 2 Filament-like plant protein, long coiled-coil Fib_alpha PF08702.10 AAG06040.1 - 0.0052 17.0 9.9 0.36 11.0 2.1 3.8 3 2 1 4 4 3 1 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 AAG06040.1 - 0.0093 16.0 20.2 0.033 14.3 7.1 3.3 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 AAG06040.1 - 0.013 15.3 0.5 0.013 15.3 0.5 2.5 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LXG PF04740.12 AAG06040.1 - 0.036 13.8 12.6 0.5 10.0 2.8 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 AAG06040.1 - 0.056 13.3 18.5 0.27 11.0 6.6 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 AAG06040.1 - 0.073 11.7 12.7 0.59 8.7 2.7 2.1 1 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 AAG06040.1 - 0.13 12.3 16.1 3.9 7.5 0.9 5.0 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) BAR_2 PF10455.9 AAG06040.1 - 0.25 10.4 4.3 0.16 11.1 2.2 1.6 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2913 PF11140.8 AAG06040.1 - 0.26 11.0 4.6 0.4 10.4 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) Spc7 PF08317.11 AAG06040.1 - 0.34 9.7 11.0 0.081 11.8 2.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2408 PF10303.9 AAG06040.1 - 0.35 11.4 6.4 0.37 11.3 2.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) COMMD1_N PF17221.3 AAG06040.1 - 0.38 11.1 5.7 0.13 12.6 0.6 2.7 2 1 1 3 3 2 0 COMMD1 N-terminal domain WXG100 PF06013.12 AAG06040.1 - 0.52 10.6 37.4 0.5 10.6 9.1 5.7 4 2 1 6 6 5 0 Proteins of 100 residues with WXG FlgN PF05130.12 AAG06040.1 - 0.58 10.7 23.1 0.73 10.3 1.1 3.5 1 1 2 4 4 4 0 FlgN protein UPF0242 PF06785.11 AAG06040.1 - 0.66 10.0 8.3 0.2 11.8 2.3 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ISG65-75 PF11727.8 AAG06040.1 - 1.1 8.5 18.1 1 8.5 6.9 2.8 2 1 1 3 3 3 0 Invariant surface glycoprotein Syntaxin PF00804.25 AAG06040.1 - 1.3 8.7 17.5 1.2 8.8 7.2 2.9 2 2 1 3 3 3 0 Syntaxin ZapB PF06005.12 AAG06040.1 - 1.5 9.3 17.3 12 6.4 1.0 4.9 1 1 1 3 3 3 0 Cell division protein ZapB CHDCT2 PF08074.11 AAG06040.1 - 1.6 8.9 12.8 0.38 10.9 3.6 3.3 3 1 0 3 3 3 0 CHDCT2 (NUC038) domain DUF2203 PF09969.9 AAG06040.1 - 1.6 9.5 19.5 1.6 9.5 1.3 4.6 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF5344 PF17279.2 AAG06040.1 - 1.8 9.2 9.7 1.8 9.2 0.0 4.1 2 2 1 3 3 3 0 Family of unknown function (DUF5344) DASH_Duo1 PF08651.10 AAG06040.1 - 1.8 8.4 6.6 31 4.4 0.1 4.2 3 1 1 4 4 4 0 DASH complex subunit Duo1 YkyA PF10368.9 AAG06040.1 - 1.9 8.1 8.5 1.6 8.4 1.2 2.6 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Seryl_tRNA_N PF02403.22 AAG06040.1 - 2.6 8.3 16.2 9.3 6.5 2.7 4.5 4 2 1 5 5 3 0 Seryl-tRNA synthetase N-terminal domain MCU PF04678.13 AAG06040.1 - 2.6 8.1 9.2 2.1 8.4 1.1 2.7 2 1 0 2 2 2 0 Mitochondrial calcium uniporter COG2 PF06148.11 AAG06040.1 - 2.9 8.0 14.2 2.3 8.3 1.0 4.8 3 2 1 5 5 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec34 PF04136.15 AAG06040.1 - 3 7.7 6.7 15 5.4 0.4 3.5 3 1 0 3 3 3 0 Sec34-like family Laminin_II PF06009.12 AAG06040.1 - 3.1 7.8 20.8 58 3.7 2.2 4.4 1 1 2 4 4 4 0 Laminin Domain II CorA PF01544.18 AAG06040.1 - 3.1 7.0 12.6 3.9 6.7 4.4 3.4 1 1 3 4 4 4 0 CorA-like Mg2+ transporter protein TMPIT PF07851.13 AAG06040.1 - 3.2 6.9 7.7 1 8.5 1.5 2.3 2 0 0 2 2 2 0 TMPIT-like protein SKA2 PF16740.5 AAG06040.1 - 3.8 7.3 15.1 0.94 9.3 3.2 3.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Not3 PF04065.15 AAG06040.1 - 3.9 6.8 6.9 6.5 6.1 2.5 2.4 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Vps53_N PF04100.12 AAG06040.1 - 4.3 6.2 14.0 4.5 6.1 4.0 2.6 2 1 0 2 2 2 0 Vps53-like, N-terminal Mod_r PF07200.13 AAG06040.1 - 4.8 7.3 11.1 1.9 8.6 1.6 3.5 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF4795 PF16043.5 AAG06040.1 - 5.5 6.5 13.2 5.8e+02 -0.1 13.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Lin-8 PF03353.15 AAG06040.1 - 6.1 6.3 12.2 2.2 7.8 3.3 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist YabA PF06156.13 AAG06040.1 - 6.7 7.4 9.7 54 4.5 0.1 3.8 3 1 1 4 4 3 0 Initiation control protein YabA FAP206 PF12018.8 AAG06040.1 - 8.2 5.8 9.0 1.8 8.0 1.0 2.5 2 1 1 3 3 3 0 Domain of unknown function EIF4E-T PF10477.9 AAG06040.1 - 8.4 5.1 8.8 3.2 6.5 5.8 1.4 1 1 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PHA_synth_III_E PF09712.10 AAG06040.1 - 8.5 5.4 13.4 2 7.4 1.8 2.6 1 1 1 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF4200 PF13863.6 AAG06040.1 - 8.7 6.8 11.8 4 7.9 3.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.8 AAG06040.1 - 8.8 6.4 18.5 0.57 10.2 3.2 3.3 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Na_H_antiporter PF03553.14 AAG06041.1 - 2.8e-77 259.9 19.8 5.6e-77 259.0 19.8 1.5 1 0 0 1 1 1 1 Na+/H+ antiporter family Na_H_antiport_2 PF13726.6 AAG06041.1 - 8.2e-33 112.4 32.4 5.1e-32 109.9 14.2 3.1 3 0 0 3 3 3 2 Na+-H+ antiporter family DctM PF06808.12 AAG06041.1 - 6.9e-13 48.2 33.1 1.9e-10 40.2 16.8 2.1 1 1 1 2 2 2 2 Tripartite ATP-independent periplasmic transporter, DctM component CitMHS PF03600.16 AAG06041.1 - 8.1e-07 28.5 46.3 0.014 14.6 20.7 2.1 1 1 1 2 2 2 2 Citrate transporter GntP_permease PF02447.16 AAG06041.1 - 0.00072 18.4 21.7 0.00072 18.4 21.7 2.1 1 1 1 2 2 2 2 GntP family permease DUF2407_C PF13373.6 AAG06041.1 - 7.6 6.7 5.8 0.64 10.2 0.3 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain MCPsignal PF00015.21 AAG06042.1 - 2.9e-47 160.7 31.4 2.1e-45 154.7 20.2 2.6 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAG06042.1 - 1.1e-16 61.4 0.0 1.1e-16 61.4 0.0 3.3 2 1 0 3 3 3 1 Cache domain HAMP PF00672.25 AAG06042.1 - 1.6e-11 44.4 0.1 1.6e-11 44.4 0.1 3.5 4 1 0 4 4 3 1 HAMP domain DUF948 PF06103.11 AAG06042.1 - 6.7e-07 29.5 13.7 0.0015 18.7 0.5 4.5 3 1 1 4 4 4 2 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 AAG06042.1 - 0.009 16.3 12.7 3 8.2 0.2 4.2 3 1 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NOG1 PF06858.14 AAG06042.1 - 0.018 14.8 0.1 0.053 13.3 0.1 1.8 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Neurensin PF14927.6 AAG06042.1 - 0.029 14.1 0.1 0.079 12.7 0.1 1.7 1 0 0 1 1 1 0 Neurensin AsnC_trans_reg PF01037.21 AAG06042.1 - 0.064 13.2 0.2 17 5.5 0.1 2.8 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain CREPT PF16566.5 AAG06042.1 - 2.8 8.1 6.6 1.3 9.2 1.9 2.5 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CCDC144C PF14915.6 AAG06042.1 - 3.6 6.6 9.6 0.27 10.3 3.0 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region V_ATPase_I PF01496.19 AAG06042.1 - 5.4 4.8 7.2 7.8 4.3 0.3 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family GP41 PF00517.17 AAG06042.1 - 5.5 6.8 5.7 13 5.6 1.6 2.5 2 0 0 2 2 2 0 Retroviral envelope protein HATPase_c PF02518.26 AAG06044.1 - 1.9e-14 54.1 0.0 3.1e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAG06044.1 - 0.00026 20.8 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HAMP PF00672.25 AAG06044.1 - 0.0066 16.8 0.4 0.018 15.4 0.4 1.8 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 AAG06044.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HisKA PF00512.25 AAG06044.1 - 0.067 13.2 0.8 0.067 13.2 0.8 2.7 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF948 PF06103.11 AAG06044.1 - 0.085 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HATPase_c_3 PF13589.6 AAG06044.1 - 0.1 12.4 0.0 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FlgN PF05130.12 AAG06044.1 - 0.39 11.2 9.1 0.72 10.4 9.1 1.3 1 0 0 1 1 1 0 FlgN protein DUF5345 PF17280.2 AAG06044.1 - 7 6.7 6.5 25 4.9 1.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Response_reg PF00072.24 AAG06045.1 - 1.2e-22 80.2 0.0 1.6e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG06045.1 - 1.9e-22 79.1 0.1 4.1e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal PepSY PF03413.19 AAG06046.1 - 1.4e-10 41.6 0.0 1.7e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 AAG06046.1 - 0.00014 21.7 0.3 0.00069 19.6 0.3 1.8 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY PF03413.19 AAG06047.1 - 9.7e-14 51.7 0.1 1.5e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 AAG06047.1 - 9.4e-06 25.6 1.4 2.5e-05 24.2 1.4 1.6 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain Marek_SORF3 PF07153.11 AAG06047.1 - 0.015 14.6 0.4 0.094 12.0 0.1 1.9 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein FixH PF05751.11 AAG06047.1 - 0.06 13.4 0.1 0.074 13.1 0.1 1.1 1 0 0 1 1 1 0 FixH YbgS PF13985.6 AAG06047.1 - 0.076 13.3 0.2 0.1 12.9 0.2 1.3 1 0 0 1 1 1 0 YbgS-like protein Patatin PF01734.22 AAG06048.1 - 0.00057 20.1 0.3 0.0016 18.6 0.3 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Hydrolase_4 PF12146.8 AAG06049.1 - 0.002 17.5 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DDHD PF02862.17 AAG06049.1 - 1.3 9.2 2.9 3.2 7.8 0.1 2.1 1 1 1 2 2 2 0 DDHD domain NnrS PF05940.12 AAG06050.1 - 1.1e-112 377.1 74.9 1.2e-112 376.9 74.9 1.0 1 0 0 1 1 1 1 NnrS protein DUF5316 PF17247.2 AAG06050.1 - 0.028 14.4 1.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5316) YfhO PF09586.10 AAG06050.1 - 0.067 11.4 7.5 0.11 10.8 7.5 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO UPF0220 PF05255.11 AAG06051.1 - 0.071 12.7 0.2 0.081 12.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) DUF3098 PF11297.8 AAG06051.1 - 0.15 11.7 3.3 0.62 9.7 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3098) DUF3185 PF11381.8 AAG06051.1 - 0.24 11.4 4.3 2.9 8.0 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3040 PF11239.8 AAG06051.1 - 0.74 10.1 6.6 4.4 7.6 6.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) FAD_binding_6 PF00970.24 AAG06052.1 - 1.8e-12 47.4 0.0 2.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AAG06052.1 - 8.9e-11 42.4 0.0 3.3e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 AAG06052.1 - 4.9e-09 36.7 0.0 9.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 AAG06052.1 - 0.0066 16.6 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Sigma54_activat PF00158.26 AAG06053.1 - 3.5e-69 231.8 0.0 4.9e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG06053.1 - 1.8e-22 80.0 0.0 4.2e-22 78.7 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain GAF PF01590.26 AAG06053.1 - 8.8e-10 39.3 0.0 2.7e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAG06053.1 - 2.6e-09 37.5 2.0 4.7e-09 36.7 0.1 2.5 3 0 0 3 3 3 1 GAF domain AAA_5 PF07728.14 AAG06053.1 - 5.3e-07 29.7 0.0 9.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG06053.1 - 2.4e-06 27.1 0.4 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAG06053.1 - 2.3e-05 24.8 0.0 4.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_8 PF02954.19 AAG06053.1 - 2.4e-05 24.0 2.9 5.6e-05 22.8 0.9 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_2 PF07724.14 AAG06053.1 - 0.00089 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) GAF_3 PF13492.6 AAG06053.1 - 0.0024 18.2 0.0 0.011 16.0 0.0 2.1 1 1 0 1 1 1 1 GAF domain TIP49 PF06068.13 AAG06053.1 - 0.0049 16.1 0.2 0.009 15.3 0.1 1.3 1 1 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 AAG06053.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 AAG06053.1 - 0.13 12.7 0.2 0.13 12.7 0.2 3.2 1 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 AAG06053.1 - 0.25 10.8 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PTPS PF01242.19 AAG06054.1 - 1e-38 132.0 0.0 1.1e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase WND PF07861.11 AAG06054.1 - 0.095 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 WisP family N-Terminal Region Histone_HNS PF00816.21 AAG06055.1 - 4.8e-06 27.3 0.4 6.2e-06 26.9 0.4 1.2 1 0 0 1 1 1 1 H-NS histone family ArlS_N PF18719.1 AAG06055.1 - 0.088 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 ArlS sensor domain T2SSM_b PF10741.9 AAG06057.1 - 5.7e-06 26.1 0.7 8.6e-06 25.5 0.7 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M subtype b HlyD_D4 PF16572.5 AAG06057.1 - 0.024 14.5 0.1 0.072 13.0 0.0 1.9 1 1 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB T2SSK PF03934.13 AAG06059.1 - 6.1e-07 29.1 0.3 1.3e-06 28.1 0.3 1.4 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_3 PF12836.7 AAG06059.1 - 0.0096 16.2 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSJ PF11612.8 AAG06060.1 - 2.1e-06 28.0 0.6 1.3e-05 25.4 0.6 2.0 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein J N_methyl PF07963.12 AAG06060.1 - 3.2e-05 23.3 2.3 3.2e-05 23.3 2.3 2.0 2 0 0 2 2 2 1 Prokaryotic N-terminal methylation motif N_methyl PF07963.12 AAG06061.1 - 4.1e-07 29.3 0.5 6.3e-07 28.7 0.5 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif N_methyl PF07963.12 AAG06062.1 - 7e-07 28.6 2.6 1.1e-06 28.0 2.6 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSG PF08334.11 AAG06063.1 - 2.3e-33 114.5 0.0 2.7e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AAG06063.1 - 1.7e-08 33.6 4.2 2.6e-08 33.1 4.2 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif 5TM-5TMR_LYT PF07694.12 AAG06063.1 - 0.053 13.0 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT T2SSF PF00482.23 AAG06064.1 - 2.1e-49 166.6 19.3 4.6e-28 97.7 2.8 2.7 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F Peptidase_M75 PF09375.10 AAG06064.1 - 0.052 13.0 1.3 0.072 12.6 0.1 1.7 2 0 0 2 2 2 0 Imelysin T2SSE PF00437.20 AAG06065.1 - 9.2e-81 270.9 1.1 1.2e-80 270.5 1.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AAG06065.1 - 4.6e-12 46.2 0.1 2.1e-11 44.1 0.1 2.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_29 PF13555.6 AAG06065.1 - 0.00071 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG06065.1 - 0.0017 18.7 0.1 0.0056 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAG06065.1 - 0.0034 17.6 0.0 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AAG06065.1 - 0.0089 16.0 1.4 1.1 9.1 0.3 2.4 1 1 1 2 2 2 2 NTPase AAA_18 PF13238.6 AAG06065.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAG06065.1 - 0.027 14.2 0.1 0.14 11.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 AAG06065.1 - 0.038 14.5 0.7 0.066 13.7 0.7 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAG06065.1 - 0.052 13.5 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 AAG06065.1 - 0.075 13.4 0.1 0.35 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAG06065.1 - 0.083 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAG06065.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAG06065.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF1062 PF06353.12 AAG06065.1 - 0.19 12.6 0.0 0.58 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) AAA_11 PF13086.6 AAG06065.1 - 0.22 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 AAG06066.1 - 1.5e-31 109.5 24.2 2.3e-31 108.9 24.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAG06066.1 - 0.0038 16.4 22.5 0.0038 16.4 22.5 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein Methyltransf_11 PF08241.12 AAG06067.1 - 8.5e-17 61.6 0.2 1.8e-16 60.5 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG06067.1 - 1e-14 55.0 0.1 3.1e-14 53.4 0.2 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG06067.1 - 1e-08 35.8 0.0 2.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG06067.1 - 6.7e-08 32.5 0.0 9.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG06067.1 - 3.3e-07 30.3 0.0 5.9e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 AAG06067.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 AAG06067.1 - 0.0039 17.2 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG06067.1 - 0.0042 16.7 0.1 0.0063 16.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 AAG06067.1 - 0.0079 15.3 0.0 0.0093 15.1 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase tRNA_U5-meth_tr PF05958.11 AAG06067.1 - 0.0087 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MetW PF07021.12 AAG06067.1 - 0.029 14.0 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 AAG06067.1 - 0.035 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 AAG06067.1 - 0.047 13.6 0.1 0.066 13.1 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 AAG06067.1 - 0.05 13.3 0.0 0.084 12.5 0.0 1.3 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 AAG06067.1 - 0.075 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 AAG06068.1 - 1.7e-19 70.0 0.1 2.6e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAG06068.1 - 7.1e-15 56.2 0.1 1.1e-14 55.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG06068.1 - 8.1e-07 28.9 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LysR_substrate PF03466.20 AAG06069.1 - 2.1e-46 157.9 8.2 2.1e-46 157.9 8.2 1.7 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06069.1 - 3.4e-16 58.9 2.6 8.8e-16 57.6 2.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG06069.1 - 0.0054 16.5 1.0 0.0054 16.5 1.0 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain DLH PF01738.18 AAG06070.1 - 1.1e-46 159.1 0.0 1.4e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family SnoaL_2 PF12680.7 AAG06070.1 - 3.1e-07 31.0 0.5 3.1e-07 31.0 0.5 2.2 2 1 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 AAG06070.1 - 1.8e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase BAAT_C PF08840.11 AAG06070.1 - 0.00024 21.1 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AAG06070.1 - 0.0033 16.7 0.1 1.1 8.4 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 AAG06070.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 AAG06070.1 - 0.1 12.0 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AAG06070.1 - 0.51 10.9 5.3 2.2 8.8 5.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PALP PF00291.25 AAG06071.1 - 2.8e-82 276.5 0.3 3.2e-82 276.3 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RHS_repeat PF05593.14 AAG06072.1 - 2.5e-60 200.3 77.7 4.9e-08 33.3 0.1 19.4 13 6 7 21 21 21 18 RHS Repeat RHS PF03527.14 AAG06072.1 - 1e-15 57.1 0.6 2e-14 53.0 0.1 3.3 2 0 0 2 2 2 1 RHS protein Phage_GPD PF05954.11 AAG06073.1 - 8.2e-103 343.8 0.3 1.5e-102 343.0 0.3 1.5 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Gp5_C PF06715.12 AAG06073.1 - 1.9e-08 33.9 24.2 5.7e-05 23.0 5.2 5.1 3 1 3 6 6 6 4 Gp5 C-terminal repeat (3 copies) DUF2345 PF10106.9 AAG06073.1 - 4.1e-05 23.5 0.0 0.00012 22.0 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) Response_reg PF00072.24 AAG06074.1 - 1.8e-24 86.0 0.0 3.3e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG06074.1 - 2.3e-16 59.6 0.1 4.2e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HK_sensor PF16750.5 AAG06075.1 - 1.1e-37 128.7 0.0 2.5e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 Sensor domain of 2-component histidine kinase HATPase_c PF02518.26 AAG06075.1 - 1.3e-14 54.7 0.0 1.9e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAG06075.1 - 4.1e-10 39.9 3.9 4.1e-10 39.9 3.9 2.6 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 AAG06075.1 - 6.9e-07 29.2 2.2 6.9e-07 29.2 2.2 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain kleA_kleC PF17383.2 AAG06075.1 - 2.8 8.3 6.2 1.5 9.2 1.9 2.5 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A TonB_dep_Rec PF00593.24 AAG06076.1 - 1.9e-56 192.9 27.3 1.9e-56 192.9 27.3 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG06076.1 - 3.8e-28 98.2 2.3 2.7e-27 95.5 1.8 2.5 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Esterase PF00756.20 AAG06077.1 - 1.1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AAG06077.1 - 8.1e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAG06077.1 - 0.0002 20.7 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 T3SS_ExsE PF18286.1 AAG06077.1 - 0.0047 16.8 0.1 0.021 14.8 0.1 2.2 2 0 0 2 2 2 1 Type III secretion system ExsE Abhydrolase_1 PF00561.20 AAG06077.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Transposase_20 PF02371.16 AAG06078.1 - 7.2e-25 87.1 0.7 1.9e-24 85.8 0.7 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAG06078.1 - 5.4e-15 55.6 0.2 2.4e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 Transposase Cep57_MT_bd PF06657.13 AAG06078.1 - 0.0024 18.3 0.5 0.0056 17.1 0.1 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 HHH PF00633.23 AAG06078.1 - 0.02 14.7 0.1 0.063 13.2 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lzipper-MIP1 PF14389.6 AAG06078.1 - 0.021 15.1 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_transf_4 PF13439.6 AAG06078.1 - 0.054 13.5 0.4 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HalX PF08663.10 AAG06078.1 - 0.095 13.0 1.6 0.33 11.3 1.6 1.9 1 0 0 1 1 1 0 HalX domain DUF3287 PF11690.8 AAG06078.1 - 0.11 12.2 0.6 0.31 10.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ABC_tran_CTD PF16326.5 AAG06078.1 - 0.12 12.6 1.5 0.25 11.6 1.5 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AAG06078.1 - 0.4 10.8 3.0 0.23 11.5 0.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation Pyr_redox_2 PF07992.14 AAG06079.1 - 2.2e-39 135.5 2.1 3.1e-39 135.0 2.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG06079.1 - 1.2e-09 38.5 1.4 3e-07 30.9 0.6 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAG06079.1 - 6.1e-06 26.3 7.9 1.1 9.2 0.1 4.2 2 2 2 4 4 4 3 FAD-NAD(P)-binding DAO PF01266.24 AAG06079.1 - 1.6e-05 24.7 16.5 0.12 11.9 0.0 4.1 2 2 1 4 4 4 4 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG06079.1 - 0.08 13.2 1.6 3.8 7.8 0.0 2.9 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Tudor_4 PF18358.1 AAG06079.1 - 0.088 12.4 0.3 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain GIDA PF01134.22 AAG06079.1 - 6.8 5.7 8.4 21 4.0 0.1 3.2 2 1 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 AAG06079.1 - 7.1 5.2 6.7 4 6.0 0.0 2.8 2 1 1 3 3 3 0 HI0933-like protein Rrf2 PF02082.20 AAG06080.1 - 7.8e-25 87.0 0.2 3.7e-24 84.9 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AAG06080.1 - 0.035 14.1 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 AAG06080.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB 4HBT PF03061.22 AAG06081.1 - 1e-17 64.2 0.5 1.9e-17 63.4 0.5 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Thioredoxin PF00085.20 AAG06082.1 - 9.5e-14 51.2 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AAG06082.1 - 0.00055 20.2 0.0 0.021 15.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like HyaE PF07449.11 AAG06082.1 - 0.0025 17.8 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 AAG06082.1 - 0.005 17.3 0.0 0.077 13.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AAG06082.1 - 0.0086 16.2 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 AAG06082.1 - 0.051 13.2 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) GTP_EFTU_D3 PF03143.17 AAG06082.1 - 0.22 11.8 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain DUF1615 PF07759.12 AAG06083.1 - 3e-147 490.0 0.0 3.5e-147 489.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1615) HTH_18 PF12833.7 AAG06084.1 - 5.2e-22 77.9 0.0 1.1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06084.1 - 3.7e-17 61.9 0.0 1.2e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_31 PF13560.6 AAG06084.1 - 0.0042 17.4 0.7 0.15 12.4 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG06084.1 - 0.0086 15.9 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain TetR_N PF00440.23 AAG06084.1 - 0.039 13.8 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family MarR_2 PF12802.7 AAG06084.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 AAG06084.1 - 0.052 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AAG06084.1 - 0.064 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2802 PF10975.8 AAG06084.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DUF4287 PF14117.6 AAG06084.1 - 0.17 12.1 0.0 4.4 7.5 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4287) DUF1427 PF07235.11 AAG06085.1 - 1.6e-36 124.1 2.2 1.8e-36 123.9 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1427) Isochorismatase PF00857.20 AAG06086.1 - 1.4e-27 96.9 0.1 1.9e-27 96.5 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family Amidohydro_3 PF07969.11 AAG06087.1 - 1.8e-120 403.6 0.0 2.2e-120 403.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AAG06087.1 - 1.1e-06 28.2 0.0 8.7e-05 22.0 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family OprD PF03573.13 AAG06088.1 - 1.6e-137 458.7 1.8 1.9e-137 458.5 1.8 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family MFS_3 PF05977.13 AAG06089.1 - 4.5e-221 734.8 35.1 5.1e-221 734.6 35.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AAG06089.1 - 6.9e-35 120.6 82.5 8.3e-29 100.6 47.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAG06089.1 - 1.8e-06 26.8 3.9 1.8e-06 26.8 3.9 2.9 1 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 AAG06089.1 - 0.11 11.3 19.3 0.0098 14.8 7.0 2.5 2 0 0 2 2 2 0 MFS_1 like family ADPRTs_Tse2 PF18648.1 AAG06090.1 - 4.7e-56 188.9 0.0 5.3e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Tse2 ADP-ribosyltransferase toxins DHR-2 PF06920.13 AAG06091.1 - 0.094 11.3 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Dock homology region 2 Chrome_Resist PF09828.9 AAG06091.1 - 0.13 12.7 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Chromate resistance exported protein Arabinose_bd PF12625.7 AAG06092.1 - 1.9e-44 152.0 4.9 7.2e-44 150.1 4.8 2.0 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG06092.1 - 3.1e-18 65.8 1.8 3.1e-18 65.8 1.8 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_11 PF08279.12 AAG06092.1 - 0.00047 20.0 0.2 0.046 13.7 0.1 2.5 2 0 0 2 2 2 1 HTH domain HTH_AraC PF00165.23 AAG06092.1 - 0.00094 19.2 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r4_2 PF08281.12 AAG06092.1 - 0.0055 16.4 0.4 0.94 9.2 0.1 2.5 1 1 1 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 AAG06092.1 - 0.0083 15.9 0.2 5.3 6.9 0.1 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_28 PF13518.6 AAG06092.1 - 0.041 14.0 0.3 1.5 9.1 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF746 PF05344.11 AAG06092.1 - 0.049 13.5 0.1 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_23 PF13384.6 AAG06092.1 - 0.05 13.4 0.1 11 6.0 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Mga PF08280.11 AAG06092.1 - 0.11 12.5 0.1 0.81 9.8 0.1 2.1 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_AsnC-type PF13404.6 AAG06092.1 - 0.23 11.3 3.3 5.4 6.9 0.0 3.4 3 1 0 3 3 3 0 AsnC-type helix-turn-helix domain VWA_CoxE PF05762.14 AAG06093.1 - 2.5e-10 40.1 0.0 2.6e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Nnf1 PF03980.14 AAG06093.1 - 0.075 13.4 0.3 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Nnf1 Trigger_C PF05698.14 AAG06093.1 - 1 9.3 4.3 40 4.2 2.2 2.9 2 1 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus GFA PF04828.14 AAG06094.1 - 2.4e-21 75.9 0.3 3e-21 75.6 0.3 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme AAA PF00004.29 AAG06095.1 - 5.9e-14 52.6 0.0 1.2e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAG06095.1 - 1.3e-13 51.1 0.1 2.5e-13 50.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AAG06095.1 - 1.1e-08 35.0 0.1 0.0027 17.4 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.14 AAG06095.1 - 4.4e-07 30.2 0.0 7.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AAG06095.1 - 1.2e-06 28.9 0.1 3.4e-06 27.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG06095.1 - 7.6e-06 26.4 1.5 0.00023 21.6 0.9 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 AAG06095.1 - 8.5e-05 22.5 0.2 0.0051 16.7 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 AAG06095.1 - 0.00012 22.7 0.1 0.00027 21.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG06095.1 - 0.0002 21.1 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAG06095.1 - 0.00044 20.6 0.4 0.0016 18.8 0.3 2.0 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 AAG06095.1 - 0.00067 19.5 0.1 0.18 11.7 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAG06095.1 - 0.00095 18.6 0.1 0.0035 16.7 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 AAG06095.1 - 0.0014 18.8 0.1 0.017 15.3 0.1 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 AAG06095.1 - 0.0014 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 AAG06095.1 - 0.0036 17.1 0.2 0.0094 15.7 0.2 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 AAG06095.1 - 0.0059 16.6 0.1 0.012 15.6 0.1 1.5 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 AAG06095.1 - 0.0074 16.7 0.2 0.022 15.2 0.2 1.9 1 1 0 1 1 1 1 RNA helicase ATPase PF06745.13 AAG06095.1 - 0.0077 15.6 0.1 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.6 AAG06095.1 - 0.011 15.7 0.2 0.03 14.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AAG06095.1 - 0.016 14.5 0.1 0.025 13.8 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 AAG06095.1 - 0.017 15.3 0.1 0.03 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 AAG06095.1 - 0.057 12.6 1.0 0.19 10.9 0.0 2.0 2 1 0 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 AAG06095.1 - 0.06 13.1 0.1 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein KTI12 PF08433.10 AAG06095.1 - 0.1 12.0 0.1 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 AAG06095.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF748 PF05359.11 AAG06096.1 - 2.1e-13 50.7 0.1 4.5e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF748) Bin3 PF06859.12 AAG06096.1 - 0.13 13.0 0.0 0.38 11.4 0.0 1.7 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) PALP PF00291.25 AAG06097.1 - 1.3e-66 225.0 0.7 1.6e-66 224.7 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 AAG06097.1 - 0.0027 17.7 0.7 0.016 15.2 0.4 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase LysE PF01810.18 AAG06098.1 - 2.7e-32 111.8 15.7 3.1e-32 111.6 15.7 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAG06098.1 - 0.067 12.9 9.5 0.15 11.8 9.5 1.6 1 1 0 1 1 1 0 Integral membrane protein TerC family MarC PF01914.17 AAG06098.1 - 0.39 10.1 6.7 0.25 10.7 1.2 2.1 2 0 0 2 2 2 0 MarC family integral membrane protein SBP_bac_8 PF13416.6 AAG06099.1 - 5.4e-33 115.0 1.0 6.6e-33 114.7 1.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG06099.1 - 8.9e-24 84.2 0.4 1.2e-23 83.8 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG06099.1 - 1.9e-13 51.0 3.8 3.4e-13 50.2 3.8 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG06099.1 - 6.5e-06 26.1 0.0 0.00012 22.0 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAG06099.1 - 0.00028 19.8 0.1 0.0024 16.7 0.0 2.0 2 0 0 2 2 2 1 Hypothetical lipoprotein (MG045 family) EamA PF00892.20 AAG06100.1 - 2.1e-21 76.6 33.6 4.1e-11 43.2 13.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF5325 PF17259.2 AAG06100.1 - 1.7 8.6 14.5 2 8.3 1.7 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5325) HxlR PF01638.17 AAG06101.1 - 5e-25 87.2 0.0 7.9e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix zf-ribbon_3 PF13248.6 AAG06101.1 - 0.025 14.0 1.2 0.069 12.6 0.2 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 AAG06101.1 - 0.027 14.5 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 zinc-ribbons PadR PF03551.14 AAG06101.1 - 0.048 13.6 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 AAG06101.1 - 0.069 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ADK_lid PF05191.14 AAG06101.1 - 0.2 11.6 1.6 0.44 10.6 1.6 1.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 AAG06101.1 - 1.2 9.3 7.1 1.2 9.3 2.6 2.8 3 1 0 3 3 3 0 Zinc ribbon domain Molybdopterin PF00384.22 AAG06102.1 - 2.6e-34 118.9 0.0 4.2e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAG06102.1 - 2.1e-17 63.2 0.1 9.2e-17 61.1 0.0 2.1 3 0 0 3 3 3 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAG06102.1 - 3.7e-16 58.8 0.4 3.7e-16 58.8 0.4 1.8 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain DUF3470 PF11953.8 AAG06103.1 - 1.3e-14 53.8 0.1 1.6e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3470) Fer4 PF00037.27 AAG06103.1 - 2.5e-08 33.4 19.7 3.4e-06 26.6 5.0 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAG06103.1 - 7.1e-07 29.2 7.9 0.0011 19.1 0.2 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG06103.1 - 1.5e-05 25.8 9.2 0.0015 19.4 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAG06103.1 - 2.7e-05 24.7 16.6 0.0003 21.3 17.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG06103.1 - 3.4e-05 24.2 8.3 0.0031 17.9 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG06103.1 - 0.00039 20.9 7.7 0.0057 17.2 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAG06103.1 - 0.00077 19.4 13.1 0.028 14.5 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAG06103.1 - 0.00088 19.4 14.4 0.0032 17.6 14.5 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG06103.1 - 0.0014 18.6 19.0 0.0041 17.1 4.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAG06103.1 - 0.0018 18.4 19.7 0.012 15.7 4.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG06103.1 - 0.0024 18.3 14.5 0.027 14.9 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_11 PF13247.6 AAG06103.1 - 0.071 13.2 6.1 0.096 12.8 6.1 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAG06103.1 - 1.2 10.2 20.9 2.5 9.2 8.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Oxidored_FMN PF00724.20 AAG06104.1 - 7.6e-49 166.8 0.0 9.4e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 AAG06104.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Ala_racemase_N PF01168.20 AAG06104.1 - 0.00018 21.2 0.5 0.074 12.7 0.1 2.3 2 0 0 2 2 2 2 Alanine racemase, N-terminal domain Dus PF01207.17 AAG06104.1 - 0.0032 16.6 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) MR_MLE_C PF13378.6 AAG06104.1 - 0.0042 16.7 0.2 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like TMP-TENI PF02581.17 AAG06104.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.7 1 0 0 1 1 1 0 Thiamine monophosphate synthase NMO PF03060.15 AAG06104.1 - 0.042 13.2 1.1 0.062 12.7 1.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Abhydrolase_1 PF00561.20 AAG06105.1 - 9.9e-25 87.6 1.2 1.9e-24 86.7 1.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06105.1 - 1.1e-22 80.5 0.3 6.8e-14 51.7 0.4 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAG06105.1 - 4e-16 60.3 5.4 5e-16 60.0 5.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAG06105.1 - 9.6e-08 31.8 0.0 4.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 AAG06105.1 - 1e-05 25.3 0.1 0.0066 16.1 0.1 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 AAG06105.1 - 0.0013 18.4 0.1 0.027 14.2 0.0 2.1 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 AAG06105.1 - 0.0041 16.9 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 AAG06105.1 - 0.049 13.8 0.0 0.43 10.7 0.0 2.3 3 0 0 3 3 3 0 TAP-like protein DUF1749 PF08538.10 AAG06105.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF915 PF06028.11 AAG06105.1 - 0.081 12.2 0.1 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 AAG06105.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family MerR_1 PF13411.6 AAG06106.1 - 1.4e-15 57.1 0.0 2.9e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAG06106.1 - 8.3e-14 51.1 0.5 1.7e-13 50.1 0.5 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 AAG06106.1 - 7.4e-13 48.8 0.9 7.4e-13 48.8 0.9 1.6 2 0 0 2 2 2 1 MerR, DNA binding DUF848 PF05852.11 AAG06106.1 - 0.052 13.7 0.3 0.073 13.2 0.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) HTH_IclR PF09339.10 AAG06106.1 - 0.066 13.0 0.4 14 5.6 0.0 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain DJ-1_PfpI PF01965.24 AAG06107.1 - 1.8e-14 53.9 0.0 3.1e-14 53.1 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AAG06107.1 - 0.14 11.9 0.0 4 7.1 0.0 2.2 1 1 0 1 1 1 0 ThiJ/PfpI family-like 3-dmu-9_3-mt PF06983.13 AAG06109.1 - 1.4e-46 157.8 0.0 1.7e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase TM_PBP2_N PF16296.5 AAG06109.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters GFA PF04828.14 AAG06110.1 - 1.2e-17 64.0 0.1 1.8e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme AAA_2 PF07724.14 AAG06113.1 - 2.2e-32 112.6 0.0 3.8e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 AAG06113.1 - 3.6e-10 40.0 0.0 7.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 AAG06113.1 - 1.1e-05 25.3 0.1 3.2e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AAG06113.1 - 1.7e-05 25.3 0.0 4.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AAG06113.1 - 0.00031 20.5 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 AAG06113.1 - 0.00037 20.8 0.1 0.025 14.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 AAG06113.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAG06113.1 - 0.023 15.1 7.9 0.064 13.6 0.1 3.7 4 1 0 4 4 4 0 AAA ATPase domain AAA_PrkA PF08298.11 AAG06113.1 - 0.072 12.0 0.0 0.55 9.1 0.0 1.9 2 0 0 2 2 2 0 PrkA AAA domain CoiA PF06054.11 AAG06113.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family AAA_18 PF13238.6 AAG06113.1 - 0.13 12.8 0.0 0.45 11.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain Fer4_12 PF13353.6 AAG06114.1 - 8e-23 81.2 0.0 1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAG06114.1 - 9.4e-10 38.7 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AAG06114.1 - 9.2e-05 22.9 0.0 0.0001 22.7 0.0 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Pkinase PF00069.25 AAG06115.1 - 8.8e-19 67.9 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF4011 PF13195.6 AAG06115.1 - 1.3e-09 38.2 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4011) AAA_11 PF13086.6 AAG06115.1 - 4.5e-07 29.9 0.0 7.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.17 AAG06115.1 - 1e-06 28.3 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_19 PF13245.6 AAG06115.1 - 9.7e-05 22.7 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG06115.1 - 0.0014 19.0 0.2 0.0014 19.0 0.2 3.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 AAG06115.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 AAG06115.1 - 0.059 12.6 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 AAG06115.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DZR PF12773.7 AAG06115.1 - 0.5 10.4 4.4 12 6.0 1.4 2.3 1 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 AAG06115.1 - 0.64 9.8 2.6 5.3 6.9 1.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 AAG06115.1 - 1.3 8.6 4.7 5.3 6.6 0.6 2.7 2 0 0 2 2 2 0 zinc-ribbon domain AAA_12 PF13087.6 AAG06116.1 - 4.7e-23 81.9 0.2 1.1e-22 80.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain MTES_1575 PF18741.1 AAG06116.1 - 1.4e-15 57.3 0.0 3.7e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 REase_MTES_1575 AAA_11 PF13086.6 AAG06116.1 - 0.0025 17.7 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mor PF08765.11 AAG06116.1 - 0.031 14.3 0.0 0.09 12.8 0.0 1.8 1 0 0 1 1 1 0 Mor transcription activator family UvrD_C_2 PF13538.6 AAG06116.1 - 0.18 11.7 1.0 1.2 9.1 1.0 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain CorA PF01544.18 AAG06117.1 - 0.058 12.7 24.4 0.0094 15.3 7.0 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein E2_bind PF08825.10 AAG06118.1 - 0.098 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 E2 binding domain SWI2_SNF2 PF18766.1 AAG06120.1 - 5.1e-26 91.7 0.8 4.6e-25 88.6 0.8 2.3 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 AAG06120.1 - 1.5e-17 64.2 0.0 5.3e-17 62.4 0.0 2.0 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 AAG06120.1 - 3.4e-11 43.4 0.0 9.9e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AAG06120.1 - 2.7e-06 27.3 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 AAG06120.1 - 0.032 13.7 3.6 0.22 11.0 3.6 2.2 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 AAG06120.1 - 0.062 13.4 0.0 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Virulence_RhuM PF13310.6 AAG06121.1 - 2.6e-54 184.1 3.9 3e-54 183.9 3.9 1.0 1 0 0 1 1 1 1 Virulence protein RhuM family GatB_Yqey PF02637.18 AAG06121.1 - 0.081 12.8 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 GatB domain Methylase_S PF01420.19 AAG06122.1 - 2.3e-05 24.7 0.0 0.038 14.2 0.0 2.2 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain N6_Mtase PF02384.16 AAG06123.1 - 9.1e-52 176.2 0.0 1.3e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 AAG06123.1 - 6.7e-21 75.4 0.6 2.3e-20 73.6 0.2 2.2 2 0 0 2 2 2 1 HsdM N-terminal domain UPF0020 PF01170.18 AAG06123.1 - 0.0036 17.0 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Eco57I PF07669.11 AAG06123.1 - 0.14 12.7 0.0 2 9.0 0.0 2.5 1 1 0 1 1 1 0 Eco57I restriction-modification methylase MarR PF01047.22 AAG06124.1 - 2.1e-07 30.7 0.2 3.1e-07 30.2 0.2 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAG06124.1 - 1.3e-06 28.3 0.6 1.9e-06 27.8 0.6 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG06124.1 - 0.0012 18.7 0.2 0.0019 18.2 0.2 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAG06124.1 - 0.0037 16.8 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAG06124.1 - 0.0084 15.9 0.3 0.014 15.2 0.3 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AAG06124.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAG06124.1 - 0.034 14.0 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 AAG06124.1 - 0.041 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_15 PF12324.8 AAG06124.1 - 0.054 13.4 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase DinB_2 PF12867.7 AAG06124.1 - 0.16 12.5 0.0 0.19 12.2 0.0 1.1 1 0 0 1 1 1 0 DinB superfamily MerR_1 PF13411.6 AAG06125.1 - 2.4e-16 59.6 0.5 3.4e-16 59.1 0.5 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAG06125.1 - 0.0017 18.1 1.1 0.0032 17.2 1.1 1.5 1 0 0 1 1 1 1 MerR family regulatory protein Bac_DNA_binding PF00216.21 AAG06126.1 - 1.5e-31 108.4 0.3 1.7e-31 108.2 0.3 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-CCDC81_bac_2 PF18175.1 AAG06126.1 - 7.7e-06 25.7 0.2 1.2e-05 25.1 0.2 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-HIG PF18291.1 AAG06126.1 - 7.9e-06 26.0 0.0 9.3e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 AAG06126.1 - 0.046 13.9 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Meth_synt_1 PF08267.12 AAG06126.1 - 0.077 12.5 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain HrcA PF01628.21 AAG06126.1 - 0.15 11.9 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 HrcA protein C terminal domain B3_4 PF03483.17 AAG06127.1 - 1.2e-70 236.7 0.0 2e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 AAG06127.1 - 7.6e-62 208.5 0.0 1.1e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 AAG06127.1 - 4.3e-31 107.2 0.0 8e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 AAG06127.1 - 5.6e-25 87.3 0.1 1.2e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 AAG06127.1 - 1.2e-19 70.3 0.0 5e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 AAG06128.1 - 5.4e-109 363.4 0.0 7.4e-109 362.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 AAG06128.1 - 1.6e-27 95.2 1.3 3.5e-27 94.1 1.3 1.6 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_synthFbeta PF17759.1 AAG06128.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain Ribosomal_L20 PF00453.18 AAG06129.1 - 7.2e-49 164.3 10.4 8.2e-49 164.2 10.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 Ribosomal_L35p PF01632.19 AAG06130.1 - 3.5e-23 81.9 11.7 3.8e-23 81.7 11.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 IF3_C PF00707.22 AAG06131.1 - 2.1e-37 126.9 0.3 3.6e-37 126.2 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 AAG06131.1 - 3.5e-30 104.1 0.3 8.7e-30 102.8 0.1 1.7 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain tRNA-synt_2b PF00587.25 AAG06132.1 - 3.6e-46 157.4 0.0 8.3e-46 156.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAG06132.1 - 2.1e-19 69.5 0.1 5.2e-19 68.2 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 AAG06132.1 - 1.5e-14 53.8 0.0 3.2e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 AAG06132.1 - 1.6e-10 40.9 0.1 4.2e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 TGS domain Abhydrolase_6 PF12697.7 AAG06133.1 - 4.2e-16 60.2 10.4 5e-16 60.0 10.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG06133.1 - 6.2e-10 39.2 0.0 2.7e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06133.1 - 4.5e-06 26.1 0.0 0.0022 17.3 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF2974 PF11187.8 AAG06133.1 - 0.0063 16.1 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 AAG06133.1 - 0.0097 15.8 0.1 0.061 13.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 AAG06133.1 - 0.012 15.3 0.0 2.6 7.7 0.0 2.2 1 1 1 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 AAG06133.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.10 AAG06133.1 - 0.053 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Chlorophyllase2 PF12740.7 AAG06133.1 - 0.076 11.9 0.0 0.14 11.1 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 AAG06133.1 - 0.16 11.5 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF3509 PF12021.8 AAG06135.1 - 1.7e-32 111.0 0.1 1.9e-32 110.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3509) Peptidase_M24 PF00557.24 AAG06136.1 - 1.6e-51 175.0 0.8 1.8e-51 174.8 0.8 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 HTH_23 PF13384.6 AAG06136.1 - 0.0095 15.7 0.4 0.4 10.5 0.2 3.0 3 0 0 3 3 3 1 Homeodomain-like domain Glyco_hydro_62 PF03664.13 AAG06136.1 - 0.038 13.3 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 DUF2815 PF10991.8 AAG06136.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) Endonuclease_1 PF04231.13 AAG06137.1 - 4.8e-38 131.2 1.3 1.1e-37 130.0 1.3 1.5 1 1 0 1 1 1 1 Endonuclease I SNase PF00565.17 AAG06138.1 - 5e-07 30.2 0.0 6.3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Virul_fac_BrkB PF03631.15 AAG06139.1 - 1.6e-70 237.7 27.1 1.8e-70 237.5 27.1 1.0 1 0 0 1 1 1 1 Virulence factor BrkB SNARE_assoc PF09335.11 AAG06140.1 - 5e-14 52.8 3.2 7.2e-14 52.3 3.2 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF5064 PF16703.5 AAG06141.1 - 5.2e-46 155.9 0.3 5.8e-46 155.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5064) SnoaL PF07366.12 AAG06141.1 - 0.0063 16.3 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF883 PF05957.13 AAG06142.1 - 1.9e-29 102.1 1.4 2.6e-29 101.6 1.4 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) HBM PF16591.5 AAG06142.1 - 0.0015 18.0 2.8 0.0019 17.7 2.8 1.0 1 0 0 1 1 1 1 Helical bimodular sensor domain FliJ PF02050.16 AAG06142.1 - 0.0056 16.9 2.0 0.0072 16.6 2.0 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein Syntaxin_2 PF14523.6 AAG06142.1 - 0.021 15.2 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 Syntaxin-like protein Apolipoprotein PF01442.18 AAG06142.1 - 0.028 14.3 3.2 0.037 13.9 3.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSCB_C PF07743.13 AAG06142.1 - 0.038 14.5 1.0 4.2 7.9 0.1 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain COG5 PF10392.9 AAG06142.1 - 0.11 12.6 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF5132 PF17195.4 AAG06142.1 - 0.3 11.2 3.0 1.1 9.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Ecotin PF03974.13 AAG06143.1 - 5.7e-51 171.6 0.0 6.8e-51 171.4 0.0 1.1 1 0 0 1 1 1 1 Ecotin Dodecin PF07311.12 AAG06144.1 - 0.19 12.0 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 Dodecin BTP PF05232.12 AAG06145.1 - 5.6e-41 138.4 11.4 7e-23 80.5 6.5 2.0 2 0 0 2 2 2 2 Chlorhexidine efflux transporter GtrA PF04138.14 AAG06145.1 - 0.095 12.9 8.4 0.14 12.4 8.3 1.4 1 1 0 1 1 1 0 GtrA-like protein RseC_MucC PF04246.12 AAG06145.1 - 1.2 9.1 7.6 0.14 12.1 2.5 1.8 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LysR_substrate PF03466.20 AAG06146.1 - 4.8e-26 91.4 2.3 1.1e-25 90.3 2.3 1.6 1 1 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06146.1 - 6.4e-18 64.5 0.6 1.5e-17 63.3 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LPAM_1 PF08139.12 AAG06147.1 - 0.52 10.9 4.7 0.99 10.0 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site OprD PF03573.13 AAG06148.1 - 3.3e-141 470.9 12.0 3.7e-141 470.7 12.0 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Cupin_3 PF05899.12 AAG06150.1 - 5.3e-28 96.5 0.5 6.7e-28 96.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AAG06150.1 - 0.00016 21.4 0.1 0.00026 20.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AAG06150.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 AAG06150.1 - 0.058 13.3 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain E1-E2_ATPase PF00122.20 AAG06151.1 - 0.42 10.1 1.4 0.47 9.9 1.4 1.0 1 0 0 1 1 1 0 E1-E2 ATPase Abhydrolase_6 PF12697.7 AAG06152.1 - 3e-18 67.2 2.2 3.7e-18 67.0 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AAG06152.1 - 1.5e-05 24.9 0.2 5.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.8 AAG06152.1 - 8.3e-05 22.0 0.2 0.0014 18.0 0.1 2.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 AAG06152.1 - 0.0027 17.5 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG06152.1 - 0.0045 16.7 2.1 0.31 10.7 1.7 2.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 AAG06152.1 - 0.065 13.3 0.3 0.074 13.2 0.3 1.6 1 1 0 1 1 1 0 Thioesterase domain DUF676 PF05057.14 AAG06152.1 - 0.18 11.3 0.8 1.8 8.0 0.1 2.1 1 1 1 2 2 2 0 Putative serine esterase (DUF676) Dyp_perox PF04261.12 AAG06153.1 - 2.4e-35 122.1 0.0 4e-35 121.4 0.0 1.2 1 1 0 1 1 1 1 Dyp-type peroxidase family TetR_N PF00440.23 AAG06154.1 - 2.6e-11 43.1 0.2 8e-11 41.6 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family ECH_1 PF00378.20 AAG06155.1 - 4.2e-45 154.0 0.1 3.1e-35 121.7 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG06155.1 - 2.7e-19 69.8 0.0 8.7e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase CHAD PF05235.14 AAG06155.1 - 0.2 11.6 6.1 0.15 12.1 3.3 1.9 2 0 0 2 2 2 0 CHAD domain NUDIX PF00293.28 AAG06157.1 - 4.3e-20 72.1 0.1 4.9e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AAG06157.1 - 1.6e-05 24.8 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain PhzC-PhzF PF02567.16 AAG06158.1 - 4.1e-63 213.5 0.0 6.8e-63 212.8 0.0 1.3 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein GGDEF PF00990.21 AAG06159.1 - 1.6e-42 145.0 0.0 2.2e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF PF01590.26 AAG06159.1 - 2.2e-11 44.5 0.0 5.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAG06159.1 - 3.3e-06 27.4 0.0 8.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAG06159.1 - 0.0058 17.0 0.0 0.017 15.5 0.0 1.8 1 1 0 1 1 1 1 GAF domain GGDEF_2 PF17853.1 AAG06159.1 - 0.052 13.8 0.4 0.13 12.5 0.3 1.9 1 1 0 1 1 1 0 GGDEF-like domain ODC_AZ PF02100.17 AAG06159.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme ACP_syn_III_C PF08541.10 AAG06159.1 - 0.1 12.7 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3592 PF12158.8 AAG06163.1 - 1.4e-16 60.9 1.9 1.6e-16 60.7 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) DAO PF01266.24 AAG06164.1 - 5.6e-55 187.3 0.5 6.5e-55 187.1 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG06164.1 - 5.7e-07 29.0 0.5 1.2e-06 28.0 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 AAG06164.1 - 6.1e-06 25.7 0.8 1.2e-05 24.8 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAG06164.1 - 1.1e-05 25.5 0.6 4.7e-05 23.5 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG06164.1 - 0.00016 21.0 0.1 0.00031 20.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG06164.1 - 0.00031 19.9 0.3 0.00031 19.9 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 AAG06164.1 - 0.0014 18.3 0.2 0.0025 17.4 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 AAG06164.1 - 0.0015 19.1 0.8 0.0037 17.8 0.2 2.1 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAG06164.1 - 0.0019 17.6 0.0 0.052 12.8 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 AAG06164.1 - 0.01 14.6 0.1 0.018 13.8 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 AAG06164.1 - 0.029 14.8 0.4 0.055 13.9 0.1 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 AAG06164.1 - 0.031 13.5 0.2 0.45 9.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG06164.1 - 0.039 13.1 0.8 0.074 12.1 0.8 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 AAG06164.1 - 0.054 13.4 0.6 0.15 11.9 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Isochorismatase PF00857.20 AAG06164.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Isochorismatase family NAD_binding_9 PF13454.6 AAG06164.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Form_Nir_trans PF01226.17 AAG06165.1 - 1.1e-42 146.0 18.3 1.3e-42 145.8 18.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Peptidase_C39_2 PF13529.6 AAG06166.1 - 3.7e-08 34.0 0.0 2e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase_C39 like family TPR_16 PF13432.6 AAG06166.1 - 4.1e-07 30.5 4.8 4.1e-07 30.5 4.8 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAG06166.1 - 1.6e-06 28.0 0.3 0.0002 21.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Peptidase_C39 PF03412.15 AAG06166.1 - 1.4e-05 24.9 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family TPR_2 PF07719.17 AAG06166.1 - 4.7e-05 23.2 3.0 0.15 12.3 0.2 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAG06166.1 - 5.8e-05 23.6 4.2 0.00076 20.1 0.3 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAG06166.1 - 0.22 12.2 2.6 18 6.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AidB_N PF18158.1 AAG06166.1 - 0.35 10.8 4.3 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Adaptive response protein AidB N-terminal domain DUF3450 PF11932.8 AAG06167.1 - 0.03 13.6 2.5 0.038 13.3 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1967 PF09269.11 AAG06167.1 - 0.13 12.2 0.5 0.31 11.0 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1967) Amnionless PF14828.6 AAG06167.1 - 0.16 10.8 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Amnionless HTH_31 PF13560.6 AAG06168.1 - 7.3e-08 32.6 0.1 1.2e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAG06168.1 - 6.2e-07 29.4 0.2 1e-05 25.5 0.1 2.4 2 1 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 AAG06168.1 - 5.7e-05 23.1 0.0 7.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2281 PF10047.9 AAG06168.1 - 0.071 13.8 0.1 0.13 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Pou PF00157.17 AAG06168.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Reprolysin_3 PF13582.6 AAG06171.1 - 4.6e-25 88.5 0.1 7.3e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 AAG06171.1 - 1.2e-16 61.0 0.1 2.8e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CBM_4_9 PF02018.17 AAG06171.1 - 4.3e-16 59.4 0.0 1.8e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate binding domain Reprolysin_5 PF13688.6 AAG06171.1 - 3.3e-15 56.7 0.1 5.5e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 AAG06171.1 - 0.00061 18.8 2.0 0.00093 18.2 2.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 AAG06171.1 - 0.025 14.4 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M6 PF05547.11 AAG06171.1 - 0.025 12.9 0.5 0.04 12.3 0.5 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Reprolysin_2 PF13574.6 AAG06171.1 - 0.12 12.3 0.7 0.22 11.4 0.7 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF2975 PF11188.8 AAG06172.1 - 6e-11 42.4 6.2 1.3e-10 41.2 6.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2975) HTH_26 PF13443.6 AAG06173.1 - 5.6e-21 74.7 0.2 6.2e-21 74.6 0.2 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 AAG06173.1 - 0.00033 20.7 0.1 0.00041 20.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAG06173.1 - 0.0055 17.0 0.0 0.0065 16.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAG06173.1 - 0.011 15.7 0.2 0.014 15.4 0.2 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 AAG06173.1 - 0.085 12.7 0.1 0.21 11.4 0.1 1.6 2 0 0 2 2 2 0 HTH DNA binding domain DUF473 PF04322.12 AAG06173.1 - 0.18 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF473) GAF_2 PF13185.6 AAG06174.1 - 2.7e-07 31.0 0.1 3.1e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AAG06174.1 - 1e-06 29.4 0.0 1.2e-06 29.2 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAG06174.1 - 0.00064 20.1 0.0 0.00089 19.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain Autoind_bind PF03472.15 AAG06174.1 - 0.11 12.0 0.0 1.4 8.4 0.0 2.0 2 0 0 2 2 2 0 Autoinducer binding domain Peptidase_M20 PF01546.28 AAG06175.1 - 2.3e-31 109.1 0.0 3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAG06175.1 - 5.5e-20 71.3 0.0 9.8e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AAG06175.1 - 5e-09 36.1 0.0 8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 CHASE3 PF05227.13 AAG06175.1 - 0.025 14.5 1.1 0.089 12.7 0.1 2.1 2 0 0 2 2 2 0 CHASE3 domain MCPsignal PF00015.21 AAG06176.1 - 1.9e-46 158.0 31.9 1.1e-43 149.0 20.7 2.7 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PilJ PF13675.6 AAG06176.1 - 2.4e-15 56.5 3.8 2.4e-15 56.5 3.8 4.8 2 1 2 4 4 4 1 Type IV pili methyl-accepting chemotaxis transducer N-term HAMP PF00672.25 AAG06176.1 - 0.003 17.9 0.2 0.003 17.9 0.2 4.2 5 0 0 5 5 5 1 HAMP domain DUF948 PF06103.11 AAG06176.1 - 0.0046 17.2 24.7 0.038 14.2 0.5 5.3 5 1 1 6 6 5 2 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 AAG06176.1 - 0.038 14.3 11.9 4.7 7.6 1.3 4.6 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 AAG06176.1 - 0.089 11.7 10.5 0.84 8.5 0.7 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein FlgN PF05130.12 AAG06176.1 - 0.21 12.1 25.3 1.6 9.2 0.4 4.4 3 1 1 4 4 4 0 FlgN protein Aida_N PF08910.10 AAG06176.1 - 0.46 10.9 2.7 5 7.6 0.1 3.3 3 0 0 3 3 3 0 Aida N-terminus Laminin_II PF06009.12 AAG06176.1 - 0.64 10.0 20.9 2.1 8.4 2.9 4.2 1 1 3 4 4 4 0 Laminin Domain II Fib_alpha PF08702.10 AAG06176.1 - 1.1 9.4 5.8 17 5.6 0.2 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 AAG06176.1 - 1.1 9.8 7.0 1.1 9.9 0.4 3.5 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Mito_fiss_reg PF05308.11 AAG06176.1 - 1.2 9.2 4.2 2.7 8.0 4.2 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Vps53_N PF04100.12 AAG06176.1 - 1.7 7.5 8.3 6.7 5.6 2.8 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal GIT1_C PF12205.8 AAG06176.1 - 2.4 8.3 6.7 1.4 9.0 1.3 2.5 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term AbiEi_1 PF09407.10 AAG06176.1 - 4.1 7.7 9.9 0.61 10.4 3.4 2.8 3 1 0 3 3 3 0 AbiEi antitoxin C-terminal domain Snapin_Pallidin PF14712.6 AAG06176.1 - 4.5 7.8 13.1 2 8.9 0.3 4.7 4 1 0 5 5 5 0 Snapin/Pallidin Tmemb_cc2 PF10267.9 AAG06176.1 - 5.5 6.0 11.5 74 2.3 11.3 2.1 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Dor1 PF04124.12 AAG06176.1 - 8.8 4.9 14.7 0.54 8.9 2.1 2.9 3 1 0 3 3 3 0 Dor1-like family DUF5412 PF17428.2 AAG06178.1 - 0.19 11.5 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5412) LptD PF04453.14 AAG06181.1 - 0.056 12.7 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 LPS transport system D BNR_2 PF13088.6 AAG06182.1 - 6e-10 38.9 0.0 1.2e-08 34.6 0.0 2.2 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 AAG06182.1 - 0.00069 19.2 11.9 2.6 8.4 0.2 4.5 4 0 0 4 4 4 3 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 AAG06182.1 - 0.49 9.1 5.9 1.1 8.0 0.1 2.4 2 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, Dus PF01207.17 AAG06183.1 - 3.9e-83 279.1 0.0 4.6e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AAG06183.1 - 0.086 12.3 0.0 0.6 9.5 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein TAL_FSA PF00923.19 AAG06184.1 - 9.7e-97 323.8 0.0 1.1e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase STAS PF01740.21 AAG06185.1 - 3.2e-06 26.7 0.2 4.6e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AAG06185.1 - 0.00022 21.5 0.0 0.00034 20.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain SpoIIE PF07228.12 AAG06186.1 - 1.8e-30 106.3 0.0 2.8e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AAG06186.1 - 1e-29 103.0 0.1 1.6e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain ThiG PF05690.14 AAG06186.1 - 0.018 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PilZ PF07238.14 AAG06187.1 - 3.1e-13 49.9 0.0 3.4e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 PilZ domain MlaA PF04333.13 AAG06188.1 - 2.2e-77 259.2 0.3 2.5e-77 259.0 0.3 1.0 1 0 0 1 1 1 1 MlaA lipoprotein 4HBT_2 PF13279.6 AAG06189.1 - 3.6e-14 53.3 0.0 4.2e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAG06189.1 - 1.7e-13 50.7 0.1 2.9e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 AAG06189.1 - 1.2e-05 24.7 0.0 2.5e-05 23.7 0.1 1.4 2 0 0 2 2 2 1 Acyl-ACP thioesterase UTRA PF07702.13 AAG06190.1 - 3.5e-36 124.2 0.1 5.2e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAG06190.1 - 1.9e-17 62.7 0.4 3.3e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAG06190.1 - 0.0028 17.6 0.1 0.0071 16.3 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AAG06190.1 - 0.0057 16.6 0.1 0.021 14.7 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 AAG06190.1 - 0.041 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain TrmB PF01978.19 AAG06190.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 AAG06190.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_28 PF13518.6 AAG06190.1 - 0.094 12.9 1.9 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HD PF01966.22 AAG06192.1 - 1.4e-08 34.9 0.1 2.4e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 AAG06192.1 - 0.00024 20.9 0.3 0.00041 20.1 0.3 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AAG06192.1 - 0.0031 17.0 0.3 0.016 14.7 0.1 1.9 2 0 0 2 2 2 1 HDOD domain MIOX PF05153.15 AAG06192.1 - 0.047 13.3 0.1 0.11 12.0 0.0 1.6 2 1 0 2 2 2 0 Myo-inositol oxygenase DUF4404 PF14357.6 AAG06193.1 - 3.9e-27 94.7 2.4 4.3e-27 94.6 2.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) Period_C PF12114.8 AAG06193.1 - 0.13 11.8 0.2 0.15 11.6 0.2 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region QueF_N PF14819.6 AAG06194.1 - 2.5e-46 156.5 0.0 1.7e-45 153.8 0.0 2.0 2 0 0 2 2 2 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term QueF PF14489.6 AAG06194.1 - 1e-28 99.3 0.0 1.4e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 QueF-like protein Copper-bind PF00127.20 AAG06195.1 - 3.7e-12 46.5 0.5 1.7e-05 25.2 0.1 2.1 1 1 1 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AAG06195.1 - 1.3e-09 38.0 0.0 5.5e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Cupredoxin-like domain CzcE PF16986.5 AAG06195.1 - 0.00044 20.5 0.0 0.0022 18.3 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal resistance protein CzcE Cu-oxidase_2 PF07731.14 AAG06195.1 - 0.0023 17.7 0.1 0.015 15.0 0.1 2.1 1 1 0 1 1 1 1 Multicopper oxidase SoxE PF06525.11 AAG06195.1 - 0.043 13.3 0.0 0.86 9.1 0.0 2.1 1 1 0 2 2 2 0 Sulfocyanin (SoxE) domain Response_reg PF00072.24 AAG06197.1 - 2.4e-25 88.9 0.0 3.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG06197.1 - 4.7e-25 87.5 0.0 1.1e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF2379 PF09543.10 AAG06197.1 - 0.17 12.1 3.1 2.8 8.2 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2379) HATPase_c PF02518.26 AAG06198.1 - 1.2e-22 80.6 0.0 1.9e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG06198.1 - 7.4e-14 51.5 4.0 7.5e-14 51.5 1.7 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAG06198.1 - 5.1e-08 33.2 2.3 2.1e-07 31.2 2.3 2.2 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 AAG06198.1 - 0.004 17.0 0.0 0.049 13.6 0.0 2.1 1 1 0 1 1 1 1 GHKL domain ABC2_membrane PF01061.24 AAG06199.1 - 2.4e-39 135.0 21.1 2.4e-39 135.0 21.1 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAG06199.1 - 1.8e-10 40.5 22.1 1.8e-10 40.5 22.1 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AAG06199.1 - 1.5 8.0 17.3 1.2 8.3 15.6 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 AAG06200.1 - 3e-30 105.5 0.0 9e-30 104.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAG06200.1 - 5.2e-12 46.2 3.0 1.3e-07 31.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAG06200.1 - 2.5e-05 24.2 0.0 0.027 14.2 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 AAG06200.1 - 0.00038 21.1 0.1 0.0011 19.6 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 AAG06200.1 - 0.0015 18.1 0.2 0.75 9.2 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG06200.1 - 0.0016 19.0 0.2 0.005 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAG06200.1 - 0.0025 17.5 0.3 0.0055 16.4 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG06200.1 - 0.0063 16.8 0.9 13 6.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 AAG06200.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 AAG06200.1 - 0.031 14.0 0.1 0.093 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAG06200.1 - 0.039 13.5 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 AAG06200.1 - 0.057 13.2 0.2 3.4 7.4 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal SbcCD_C PF13558.6 AAG06200.1 - 0.083 13.1 0.0 0.26 11.5 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 AAG06200.1 - 0.16 11.7 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain GST_N PF02798.20 AAG06201.1 - 1.4e-15 57.4 0.0 2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAG06201.1 - 3.6e-15 56.1 0.0 5.7e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG06201.1 - 3.3e-11 43.3 0.0 5.8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG06201.1 - 1e-07 32.1 0.0 2.1e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAG06201.1 - 0.00088 19.3 0.1 0.0023 17.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAG06201.1 - 0.0022 18.7 0.0 0.0042 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 AAG06201.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Transglut_core PF01841.19 AAG06202.1 - 6.8e-16 58.7 0.1 9.7e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core3 PF13471.6 AAG06202.1 - 0.034 14.0 1.3 0.13 12.2 1.3 2.0 1 1 0 1 1 1 0 Transglutaminase-like superfamily DUF1974 PF09317.11 AAG06203.1 - 3.4e-105 351.7 0.0 4.3e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 AAG06203.1 - 2.2e-19 70.2 0.0 5.7e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAG06203.1 - 1.3e-13 51.4 0.1 2.6e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG06203.1 - 5e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG06203.1 - 0.12 12.7 5.6 0.35 11.1 0.0 2.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Exonuc_VII_L PF02601.15 AAG06204.1 - 0.12 11.9 16.4 0.13 11.8 16.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Presenilin PF01080.17 AAG06204.1 - 3.4 6.3 10.1 3.5 6.3 10.1 1.1 1 0 0 1 1 1 0 Presenilin EAL PF00563.20 AAG06206.1 - 7.6e-66 222.0 0.0 1e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 EAL domain CSS-motif PF12792.7 AAG06206.1 - 4e-32 111.4 0.7 4e-32 111.4 0.7 1.6 2 0 0 2 2 2 1 CSS motif domain associated with EAL Mga PF05043.13 AAG06208.1 - 0.053 14.1 0.6 0.37 11.4 0.1 2.3 2 0 0 2 2 2 0 Mga helix-turn-helix domain Cytochrom_B562 PF07361.11 AAG06208.1 - 0.091 13.4 1.0 4.3 8.1 0.3 2.5 2 0 0 2 2 2 0 Cytochrome b562 Strep_SA_rep PF06696.11 AAG06208.1 - 0.12 12.5 2.5 0.34 11.0 2.5 1.8 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DivIC PF04977.15 AAG06208.1 - 2.6 7.9 6.2 2.8 7.8 0.3 3.1 3 0 0 3 3 3 0 Septum formation initiator GST_N_3 PF13417.6 AAG06209.1 - 1.4e-25 89.5 0.0 3e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG06209.1 - 8.5e-15 54.8 0.0 1.7e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAG06209.1 - 2e-14 53.7 0.0 7.1e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AAG06209.1 - 4.5e-13 49.2 0.0 8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAG06209.1 - 8.6e-12 45.1 0.0 1.6e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAG06209.1 - 8.1e-10 38.6 1.7 1.3e-09 37.9 0.9 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAG06209.1 - 0.0034 18.1 0.0 0.0099 16.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 AAG06209.1 - 0.051 13.9 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GAF_2 PF13185.6 AAG06210.1 - 8.2e-10 39.1 0.1 1.4e-09 38.4 0.1 1.4 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 AAG06210.1 - 1.8e-05 25.4 0.0 2.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain DUF815 PF05673.13 AAG06211.1 - 3.6e-104 347.4 0.0 4.1e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 AAG06211.1 - 2.4e-10 41.1 0.8 4.5e-10 40.2 0.8 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAG06211.1 - 0.00035 21.0 0.0 0.001 19.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 AAG06211.1 - 0.0023 17.3 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.6 AAG06211.1 - 0.021 14.5 0.1 0.05 13.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG06211.1 - 0.03 14.6 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAG06211.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AAG06211.1 - 0.048 12.6 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PutA_N PF18083.1 AAG06211.1 - 0.049 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Proline utilization A N-terminal domain AAA_5 PF07728.14 AAG06211.1 - 0.064 13.2 0.1 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 AAG06211.1 - 0.069 12.4 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 AAG06211.1 - 0.071 12.6 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 AAG06211.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_8 PF12780.7 AAG06211.1 - 0.11 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 RNA_helicase PF00910.22 AAG06211.1 - 0.15 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 AAG06211.1 - 0.21 11.6 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain HATPase_c PF02518.26 AAG06212.1 - 5e-29 101.1 0.0 1.1e-28 100.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAG06212.1 - 4.7e-28 97.6 0.0 1.8e-27 95.7 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AAG06212.1 - 1.1e-18 67.0 1.7 7.6e-18 64.3 0.1 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAG06212.1 - 0.00033 20.5 0.0 0.00057 19.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAG06212.1 - 0.0021 18.0 0.0 0.0066 16.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF4164 PF13747.6 AAG06212.1 - 0.036 14.4 6.1 0.11 12.8 6.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) CHASE8 PF17152.4 AAG06212.1 - 0.049 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Periplasmic sensor domain Atg14 PF10186.9 AAG06212.1 - 0.052 12.6 0.1 0.078 12.1 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 AAG06212.1 - 0.12 12.4 2.8 0.092 12.8 0.8 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 AAG06212.1 - 0.42 10.7 5.7 0.75 9.9 5.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-HC2 PF13490.6 AAG06212.1 - 0.96 9.8 3.8 1.7 8.9 0.0 3.2 3 0 0 3 3 3 0 Putative zinc-finger MarR PF01047.22 AAG06213.1 - 1.9e-11 43.7 0.0 3.8e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAG06213.1 - 2.2e-09 37.0 0.0 3.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAG06213.1 - 0.00014 22.3 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 AAG06213.1 - 0.021 14.7 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix PadR PF03551.14 AAG06213.1 - 0.045 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family GSHPx PF00255.19 AAG06214.1 - 5.9e-40 135.2 0.0 7.3e-40 134.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AAG06214.1 - 0.0026 17.7 0.1 0.0044 16.9 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 AAG06214.1 - 0.097 12.4 0.0 6.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Redoxin DUF4174 PF13778.6 AAG06214.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) SelR PF01641.18 AAG06215.1 - 2.9e-52 175.8 0.0 3.3e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 AAG06215.1 - 0.018 15.2 0.0 0.03 14.5 0.0 1.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Aminotran_1_2 PF00155.21 AAG06216.1 - 5.1e-48 164.1 0.0 5.6e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAG06216.1 - 1.3e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAG06216.1 - 0.00056 19.0 0.0 0.00082 18.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAG06216.1 - 0.055 12.7 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_M48 PF01435.18 AAG06218.1 - 1.3e-37 129.5 0.0 1.9e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AAG06218.1 - 0.00023 20.5 0.0 0.00043 19.6 0.0 1.5 1 1 0 1 1 1 1 BlaR1 peptidase M56 Ldr_toxin PF13940.6 AAG06218.1 - 0.038 14.0 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system SprT-like PF10263.9 AAG06218.1 - 0.067 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 SprT-like family PIG-Y PF15159.6 AAG06218.1 - 0.16 12.9 2.0 5.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Yip1 PF04893.17 AAG06218.1 - 9.5 5.9 12.6 9.2 5.9 4.5 2.2 2 0 0 2 2 2 0 Yip1 domain Pepdidase_M14_N PF18027.1 AAG06219.1 - 1.1e-34 119.0 0.1 2.2e-34 118.1 0.1 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 AAG06219.1 - 9.3e-19 68.3 0.0 4.8e-18 66.0 0.0 2.0 2 1 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 AAG06219.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family TPMT PF05724.11 AAG06220.1 - 3.3e-87 291.7 0.0 3.6e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Usp PF00582.26 AAG06221.1 - 6.6e-28 98.0 0.4 7.4e-28 97.8 0.4 1.0 1 0 0 1 1 1 1 Universal stress protein family HTH_IclR PF09339.10 AAG06221.1 - 0.085 12.7 0.2 0.085 12.7 0.2 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Glyco_trans_4_4 PF13579.6 AAG06221.1 - 0.44 11.0 6.6 1 9.8 6.6 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain LysR_substrate PF03466.20 AAG06222.1 - 1.1e-15 57.5 0.6 2.1e-15 56.7 0.6 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06222.1 - 1.7e-14 53.5 0.1 3.5e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG06222.1 - 0.0078 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG06222.1 - 0.016 15.1 0.1 0.07 13.0 0.1 2.0 2 0 0 2 2 2 0 MarR family MFS_1 PF07690.16 AAG06223.1 - 6.4e-31 107.6 38.6 1.1e-30 106.7 38.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG06223.1 - 0.087 11.7 7.3 0.24 10.2 7.3 1.9 1 1 0 1 1 1 0 Sugar (and other) transporter HlyD_D23 PF16576.5 AAG06224.1 - 4.3e-20 71.8 8.1 1.3e-18 67.1 5.5 2.8 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG06224.1 - 7.8e-17 61.9 5.0 1.4e-13 51.5 0.3 3.2 2 2 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG06224.1 - 1.4e-14 53.7 3.4 1.1e-13 50.8 2.2 3.0 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.20 AAG06224.1 - 4.2e-08 33.0 11.3 1.1e-07 31.6 11.3 1.9 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG06224.1 - 0.0032 17.3 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme DUF4407 PF14362.6 AAG06224.1 - 0.015 14.7 16.9 0.025 14.0 16.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2293 PF10056.9 AAG06224.1 - 0.1 12.8 1.8 0.32 11.3 1.8 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Spc7 PF08317.11 AAG06224.1 - 0.13 11.1 7.4 0.18 10.6 7.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.13 AAG06224.1 - 0.14 11.9 21.8 2.6 7.7 22.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 AAG06224.1 - 0.2 11.7 1.8 0.84 9.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 AAG06224.1 - 0.47 10.6 5.9 0.66 10.1 5.9 1.2 1 0 0 1 1 1 0 Tropomyosin like AAA_assoc_2 PF16193.5 AAG06224.1 - 0.6 10.5 4.2 0.26 11.6 1.0 1.9 2 0 0 2 2 2 0 AAA C-terminal domain TPR_MLP1_2 PF07926.12 AAG06224.1 - 0.85 9.7 15.0 3.2 7.8 14.1 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.16 AAG06224.1 - 5.9 7.1 19.5 97 3.2 11.0 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein OEP PF02321.18 AAG06225.1 - 2.2e-53 180.9 29.6 9.8e-27 94.0 8.9 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein LysR_substrate PF03466.20 AAG06226.1 - 2e-42 145.0 8.9 2.8e-42 144.5 8.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06226.1 - 1.5e-19 69.7 8.5 3.4e-19 68.6 2.7 2.5 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG06226.1 - 0.015 15.1 0.1 0.053 13.3 0.1 2.0 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG06226.1 - 0.034 14.0 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.6 AAG06226.1 - 0.04 13.3 1.7 0.053 12.9 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_50 PF18024.1 AAG06226.1 - 0.066 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG06226.1 - 0.092 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Thiamine_BP PF01910.17 AAG06226.1 - 0.12 12.3 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 Thiamine-binding protein HTH_28 PF13518.6 AAG06226.1 - 0.17 12.0 0.7 0.51 10.5 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LigB PF02900.18 AAG06227.1 - 2e-49 168.1 0.0 2.5e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DEAD PF00270.29 AAG06228.1 - 1.9e-46 158.1 0.0 7e-46 156.2 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG06228.1 - 1.6e-31 108.9 0.0 3.6e-30 104.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 AAG06228.1 - 1.6e-19 69.7 0.0 5e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 DbpA RNA binding domain ResIII PF04851.15 AAG06228.1 - 0.00025 21.1 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ECH_1 PF00378.20 AAG06229.1 - 1.2e-37 129.6 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG06229.1 - 2.8e-14 53.4 0.1 1.2e-13 51.3 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Spermine_synth PF01564.17 AAG06230.1 - 8e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_24 PF13578.6 AAG06230.1 - 0.003 18.6 0.0 0.0046 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAG06230.1 - 0.029 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_25 PF13649.6 AAG06230.1 - 0.039 14.7 0.0 0.062 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AAG06230.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DAHP_synth_2 PF01474.16 AAG06231.1 - 7.9e-208 690.3 0.0 8.9e-208 690.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family HTH_42 PF06224.12 AAG06232.1 - 1.2e-81 274.8 26.8 1.5e-81 274.5 26.8 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain DALR_2 PF09190.11 AAG06232.1 - 0.04 14.4 1.9 5.1 7.6 0.1 3.2 3 0 0 3 3 3 0 DALR domain AbiEi_4 PF13338.6 AAG06232.1 - 0.55 10.4 4.2 2 8.6 0.4 3.3 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin DUF1127 PF06568.11 AAG06233.1 - 4.1e-12 45.6 14.3 5.6e-12 45.2 14.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) LysR_substrate PF03466.20 AAG06234.1 - 1.2e-25 90.1 0.6 1.8e-25 89.6 0.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06234.1 - 4.1e-22 77.9 2.7 7.6e-22 77.0 2.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family TauE PF01925.19 AAG06235.1 - 1.6e-46 158.9 36.9 1.8e-46 158.7 36.9 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Phage_holin_3_1 PF05106.12 AAG06235.1 - 3.4 8.2 6.7 0.49 10.9 0.4 2.6 2 1 0 2 2 2 0 Phage holin family (Lysis protein S) LysR_substrate PF03466.20 AAG06236.1 - 4.6e-35 120.9 5.7 4.6e-35 120.9 5.7 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06236.1 - 1.7e-13 50.3 0.3 3.5e-13 49.3 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 AAG06236.1 - 0.033 13.6 0.0 0.15 11.5 0.0 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2894 PF11445.8 AAG06236.1 - 0.065 13.7 2.0 1 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) HTH_28 PF13518.6 AAG06236.1 - 0.088 12.9 0.2 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 AAG06237.1 - 9.3e-16 57.5 0.0 1.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAG06237.1 - 7.2e-12 45.0 0.1 1.1e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAG06237.1 - 1.6e-08 34.9 0.3 7.9e-08 32.7 0.2 1.9 1 1 1 2 2 2 1 Winged helix DNA-binding domain PadR PF03551.14 AAG06237.1 - 5.3e-05 23.1 0.1 0.0001 22.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_20 PF12840.7 AAG06237.1 - 0.00039 20.4 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HxlR PF01638.17 AAG06237.1 - 0.00096 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 AAG06237.1 - 0.0022 18.1 0.1 0.0051 16.9 0.0 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 AAG06237.1 - 0.071 13.0 0.1 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 AAG06237.1 - 0.077 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Penicillinase_R PF03965.16 AAG06237.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 1 0 1 1 1 0 Penicillinase repressor OsmC PF02566.19 AAG06238.1 - 3.8e-17 62.6 0.0 6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein EFP_N PF08207.12 AAG06239.1 - 7.8e-22 77.1 0.1 1.4e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 AAG06239.1 - 1.7e-21 75.7 0.1 3.4e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 AAG06239.1 - 5.3e-13 48.8 3.6 8.4e-13 48.1 3.6 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EarP PF10093.9 AAG06240.1 - 2.5e-152 507.3 0.1 2.8e-152 507.1 0.1 1.0 1 0 0 1 1 1 1 Elongation-Factor P (EF-P) rhamnosyltransferase EarP Alanine_zipper PF11839.8 AAG06241.1 - 3.2e-11 43.4 21.5 4.2e-11 43.0 21.5 1.2 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein SMBP PF16785.5 AAG06241.1 - 0.027 14.7 8.2 0.029 14.6 8.2 1.0 1 0 0 1 1 1 0 Small metal-binding protein CinA_KH PF18146.1 AAG06241.1 - 0.47 10.6 6.3 0.13 12.4 2.0 1.9 1 1 1 2 2 2 0 Damage-inducible protein CinA KH domain LEA_4 PF02987.16 AAG06241.1 - 1.3 9.2 13.4 1.1 9.4 1.3 2.3 1 1 0 2 2 2 0 Late embryogenesis abundant protein DUF3560 PF12083.8 AAG06241.1 - 4 7.6 14.1 1.3 9.2 6.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3560) Sugarporin_N PF11471.8 AAG06241.1 - 6.4 6.8 19.0 0.34 10.9 8.0 2.3 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension YkuD PF03734.14 AAG06242.1 - 5.7e-16 59.2 0.1 9.8e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Ldt_C PF17969.1 AAG06242.1 - 0.00012 22.7 0.0 0.0002 22.0 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase C-terminal domain Lipase_GDSL_2 PF13472.6 AAG06244.1 - 1e-23 84.6 0.1 1.3e-23 84.3 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AAG06244.1 - 2.3e-08 34.3 0.0 2.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 AAG06244.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 OSK domain ABC_tran PF00005.27 AAG06245.1 - 8.1e-32 110.6 0.0 1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06245.1 - 2.1e-06 27.8 0.5 0.023 14.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG06245.1 - 8.8e-06 25.3 0.1 0.00021 20.8 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG06245.1 - 0.00014 21.6 0.7 0.00067 19.3 0.4 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG06245.1 - 0.00039 20.8 2.9 0.00066 20.1 2.9 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG06245.1 - 0.0017 18.3 0.2 0.0029 17.5 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 AAG06245.1 - 0.012 15.7 0.7 0.023 14.8 0.7 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 AAG06245.1 - 0.019 15.3 0.5 0.092 13.0 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAG06245.1 - 0.023 14.4 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAG06245.1 - 0.12 11.7 0.2 0.23 10.8 0.2 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.14 AAG06245.1 - 0.18 11.7 0.0 0.51 10.2 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 AAG06245.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 AAG06245.1 - 0.23 12.0 0.0 0.45 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAG06245.1 - 0.25 10.5 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 AAG06245.1 - 0.27 11.5 1.2 0.66 10.2 1.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAG06245.1 - 0.32 10.5 3.4 1.8 8.1 1.7 2.7 1 1 2 3 3 3 0 AAA domain NACHT PF05729.12 AAG06245.1 - 0.92 9.4 3.6 0.96 9.3 0.5 2.4 3 1 0 3 3 3 0 NACHT domain DinB_2 PF12867.7 AAG06246.1 - 0.095 13.2 1.2 0.58 10.7 0.2 2.6 3 0 0 3 3 3 0 DinB superfamily CwsA PF10814.8 AAG06246.1 - 1.5 9.0 6.5 0.67 10.1 0.3 3.0 2 1 0 3 3 3 0 Cell wall synthesis protein CwsA GreA_GreB_N PF03449.15 AAG06247.1 - 8.5e-25 86.7 0.1 1.2e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AAG06247.1 - 2.9e-24 84.7 0.0 5.6e-24 83.8 0.0 1.5 1 1 1 2 2 2 1 Transcription elongation factor, GreA/GreB, C-term MetW PF07021.12 AAG06248.1 - 0.17 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW LigT_PEase PF02834.16 AAG06249.1 - 9e-22 77.1 0.3 4.9e-10 39.5 0.0 2.8 2 1 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 AAG06249.1 - 1.5e-10 41.1 0.1 2.1e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Abhydrolase_1 PF00561.20 AAG06250.1 - 1.5e-24 87.0 0.0 1.8e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 AAG06250.1 - 1.5e-06 28.2 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 AAG06250.1 - 0.0056 17.3 0.3 0.0068 17.0 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 AAG06250.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 AAG06250.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 AAG06250.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_chap PF03280.14 AAG06251.1 - 1.5e-54 184.9 24.9 2.6e-54 184.1 24.9 1.4 1 0 0 1 1 1 1 Proteobacterial lipase chaperone protein DUF148 PF02520.17 AAG06251.1 - 0.0026 17.9 0.2 1.9 8.7 0.0 2.8 1 1 1 2 2 2 2 Domain of unknown function DUF148 DUF1542 PF07564.11 AAG06251.1 - 0.0074 16.4 0.1 0.39 10.9 0.2 2.6 2 1 0 2 2 2 1 Domain of Unknown Function (DUF1542) DoxX PF07681.12 AAG06252.1 - 1.9e-20 73.2 11.5 1.9e-20 73.2 11.5 1.7 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 AAG06252.1 - 0.00028 20.8 1.9 0.00028 20.8 1.9 1.9 2 0 0 2 2 2 1 TQO small subunit DoxD DoxX_2 PF13564.6 AAG06252.1 - 0.25 11.5 10.6 0.26 11.4 9.6 1.7 1 1 0 1 1 1 0 DoxX-like family SLT PF01464.20 AAG06253.1 - 5.7e-16 58.2 0.0 9.5e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain SBP_bac_3 PF00497.20 AAG06253.1 - 3.5e-08 33.2 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 TatD_DNase PF01026.21 AAG06254.1 - 2.7e-61 207.2 0.0 3e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 AAG06254.1 - 0.01 15.6 2.0 0.046 13.5 2.1 2.2 1 1 0 1 1 1 0 Amidohydrolase MCPsignal PF00015.21 AAG06255.1 - 2.9e-43 147.7 31.4 6.1e-43 146.6 21.7 2.7 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAG06255.1 - 1.6e-14 54.0 7.7 3.6e-11 43.3 0.1 4.5 3 0 0 3 3 3 2 HAMP domain APG17 PF04108.12 AAG06255.1 - 0.15 11.1 11.1 0.014 14.5 2.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF948 PF06103.11 AAG06255.1 - 0.18 12.1 0.1 0.18 12.1 0.1 5.5 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF724 PF05266.14 AAG06255.1 - 0.4 10.5 4.2 1.9 8.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Sec8_exocyst PF04048.14 AAG06255.1 - 1.3 8.9 5.0 8.4 6.3 0.1 3.4 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain AIP3 PF03915.13 AAG06255.1 - 1.7 7.7 9.7 3.1 6.8 1.1 2.1 1 1 0 2 2 2 0 Actin interacting protein 3 AAA_27 PF13514.6 AAG06255.1 - 5.6 6.5 9.7 0.9 9.1 1.2 2.7 1 1 1 3 3 3 0 AAA domain FlgN PF05130.12 AAG06255.1 - 6.6 7.2 15.2 0.97 9.9 1.0 3.1 2 1 1 3 3 3 0 FlgN protein DUF1664 PF07889.12 AAG06255.1 - 9.3 6.3 12.6 16 5.5 1.5 3.9 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) PTRF_SDPR PF15237.6 AAG06255.1 - 9.8 5.7 8.6 0.3 10.7 0.3 2.5 2 1 1 3 3 3 0 PTRF/SDPR family DUF962 PF06127.11 AAG06256.1 - 4.1e-07 30.0 0.1 6.6e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF373 PF04123.13 AAG06256.1 - 0.076 12.4 0.1 0.085 12.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3040 PF11239.8 AAG06256.1 - 0.15 12.3 1.7 0.25 11.7 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Oxidored_molyb PF00174.19 AAG06257.1 - 7.4e-06 25.7 0.0 0.00034 20.3 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain GGDEF PF00990.21 AAG06258.1 - 1.5e-47 161.3 0.1 2.6e-47 160.6 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PepSY_TM PF03929.16 AAG06258.1 - 0.084 12.5 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 PepSY-associated TM region 4HBT_3 PF13622.6 AAG06259.1 - 1.3e-51 176.3 4.2 1.5e-51 176.1 4.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAG06259.1 - 0.0038 17.6 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 Thioesterase superfamily LysR_substrate PF03466.20 AAG06259.1 - 0.014 14.8 0.3 0.022 14.1 0.3 1.4 1 0 0 1 1 1 0 LysR substrate binding domain CHAD PF05235.14 AAG06260.1 - 4.9e-27 95.4 10.0 4.9e-27 95.4 10.0 1.3 2 0 0 2 2 2 1 CHAD domain DUF3488 PF11992.8 AAG06261.1 - 1e-108 363.1 20.9 1.6e-108 362.5 20.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3488) Transglut_core PF01841.19 AAG06261.1 - 1.2e-23 83.7 0.1 3.1e-23 82.4 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4129 PF13559.6 AAG06261.1 - 1.4e-10 41.2 6.6 1.4e-10 41.2 6.6 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4129) Transglut_core3 PF13471.6 AAG06261.1 - 0.0006 19.7 0.7 0.0029 17.5 0.7 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily Transglut_i_TM PF14400.6 AAG06261.1 - 0.0042 17.2 0.1 0.0073 16.4 0.1 1.3 1 0 0 1 1 1 1 Inactive transglutaminase fused to 7 transmembrane helices DUF58 PF01882.18 AAG06262.1 - 3e-11 43.5 0.0 6.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF58 CcmD PF04995.14 AAG06262.1 - 1.2 9.3 13.0 4.8 7.3 0.9 3.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) AAA_3 PF07726.11 AAG06263.1 - 8e-62 206.9 0.0 1.1e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAG06263.1 - 3e-22 78.3 1.3 3e-22 78.3 1.3 2.2 2 0 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 AAG06263.1 - 5.6e-12 45.8 0.0 1.8e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAG06263.1 - 6.8e-05 22.1 0.0 9.6e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 AAG06263.1 - 0.00015 21.5 0.0 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AAG06263.1 - 0.00061 20.2 0.0 0.0021 18.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAG06263.1 - 0.0013 18.1 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AAG06263.1 - 0.0066 16.2 0.0 0.032 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 AAG06263.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain OMPdecase PF00215.24 AAG06264.1 - 1.4e-50 172.0 0.0 1.5e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family LysR_substrate PF03466.20 AAG06265.1 - 7.9e-44 149.5 6.1 1.3e-43 148.8 6.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06265.1 - 3.3e-19 68.6 1.2 3.3e-19 68.6 1.2 2.3 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family YqgC PF17430.2 AAG06265.1 - 0.16 12.0 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized YqgC-like HTH_8 PF02954.19 AAG06265.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.2 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family DUF924 PF06041.11 AAG06266.1 - 8.7e-50 169.3 0.1 1e-49 169.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) LysR_substrate PF03466.20 AAG06267.1 - 1.6e-29 102.8 4.3 2.6e-29 102.1 4.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06267.1 - 6.8e-20 70.8 0.5 1.5e-19 69.7 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 AAG06267.1 - 0.037 13.8 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAG06267.1 - 0.05 13.2 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAG06267.1 - 0.052 13.7 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAG06267.1 - 0.055 13.3 0.0 0.23 11.3 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAG06267.1 - 0.11 12.0 0.1 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AAG06267.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain BTP PF05232.12 AAG06268.1 - 5.2e-49 164.2 13.5 1.1e-24 86.2 0.7 2.1 2 0 0 2 2 2 2 Chlorhexidine efflux transporter DUF2304 PF10066.9 AAG06268.1 - 0.2 11.9 6.4 0.069 13.4 3.8 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Response_reg PF00072.24 AAG06269.1 - 3.6e-29 101.2 0.0 8.5e-19 67.8 0.0 2.1 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AAG06270.1 - 4.1e-24 85.2 0.0 7.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG06270.1 - 1.1e-09 38.2 3.9 1.8e-08 34.3 0.9 3.0 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CBS PF00571.28 AAG06270.1 - 4.4e-07 30.2 0.0 2e-06 28.2 0.0 2.1 3 0 0 3 3 3 1 CBS domain HATPase_c_5 PF14501.6 AAG06270.1 - 6.9e-05 22.7 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAG06270.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FR47 PF08445.10 AAG06270.1 - 0.071 13.1 0.3 0.48 10.4 0.1 2.3 2 0 0 2 2 2 0 FR47-like protein DUF2897 PF11446.8 AAG06271.1 - 1.9e-25 88.5 0.1 2.1e-25 88.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2897) LapA_dom PF06305.11 AAG06271.1 - 0.013 15.3 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain UPF0370 PF13980.6 AAG06271.1 - 0.13 12.3 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) CPBP PF02517.16 AAG06272.1 - 5.4e-14 52.3 9.7 5.4e-14 52.3 9.7 3.1 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Dexa_ind PF15198.6 AAG06272.1 - 0.12 12.5 1.3 10 6.3 0.9 2.8 2 0 0 2 2 2 0 Dexamethasone-induced TetR_C_24 PF17932.1 AAG06273.1 - 1.3e-19 70.5 0.1 2.4e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAG06273.1 - 2.1e-16 59.5 0.1 5e-16 58.2 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family AtuA PF07287.11 AAG06274.1 - 1.7e-127 424.9 0.1 2.3e-127 424.5 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA adh_short_C2 PF13561.6 AAG06275.1 - 6.6e-54 182.9 0.7 8e-54 182.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06275.1 - 5.1e-43 146.8 0.9 6.5e-43 146.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG06275.1 - 7.5e-14 52.0 0.3 1.1e-13 51.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG06275.1 - 0.0017 17.9 0.1 0.0022 17.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 AAG06275.1 - 0.0098 15.5 0.3 0.016 14.9 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 AAG06275.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 AAG06275.1 - 0.12 11.7 0.1 0.35 10.2 0.1 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AAG06275.1 - 0.16 11.2 2.6 1 8.5 1.5 2.1 2 0 0 2 2 2 0 FAD binding domain Carboxyl_trans PF01039.22 AAG06276.1 - 3e-117 392.3 0.1 1.9e-116 389.6 0.0 1.8 1 1 1 2 2 2 1 Carboxyl transferase domain MdcE PF06833.11 AAG06276.1 - 0.028 13.9 3.8 0.16 11.5 0.0 2.8 3 0 0 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.24 AAG06277.1 - 4.6e-43 147.0 1.4 6.6e-43 146.5 1.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG06277.1 - 2.9e-33 114.9 0.0 6e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG06277.1 - 6.6e-25 87.1 0.0 1.6e-24 85.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG06277.1 - 5.3e-15 55.9 0.0 8.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG06277.1 - 0.0078 15.9 0.0 0.029 14.1 0.0 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal ECH_1 PF00378.20 AAG06278.1 - 5.3e-53 179.9 0.1 5.9e-53 179.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG06278.1 - 1.1e-36 127.1 0.2 1.3e-36 126.8 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CPSase_L_D2 PF02786.17 AAG06279.1 - 3.9e-72 242.2 0.0 5.9e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAG06279.1 - 3.6e-47 159.5 0.4 1.7e-46 157.3 0.3 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAG06279.1 - 7.4e-33 112.9 0.0 1.5e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AAG06279.1 - 6.1e-14 51.6 2.4 2e-13 49.9 1.5 2.3 2 1 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 AAG06279.1 - 7.4e-09 35.4 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAG06279.1 - 2.3e-08 33.8 0.0 4.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 AAG06279.1 - 2.3e-06 27.3 5.3 0.0001 22.1 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AAG06279.1 - 9.3e-05 23.1 1.3 0.24 12.1 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 AAG06279.1 - 0.0015 18.6 0.0 0.0036 17.4 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 AAG06279.1 - 0.0046 16.2 1.0 1.1 8.5 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion adh_short PF00106.25 AAG06280.1 - 3.3e-38 131.1 0.0 4.5e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG06280.1 - 9.8e-31 107.1 0.5 1.3e-30 106.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG06280.1 - 8.5e-08 32.3 0.3 1.2e-07 31.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG06280.1 - 0.045 13.2 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 AAG06281.1 - 1.2e-57 195.4 0.0 1.5e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG06281.1 - 8e-11 42.8 0.0 2.1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_6 PF13174.6 AAG06283.1 - 0.018 15.7 0.1 0.081 13.6 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF935 PF06074.12 AAG06283.1 - 0.25 10.1 10.3 0.049 12.4 6.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF935) Sigma70_r2 PF04542.14 AAG06284.1 - 1.9e-16 59.6 0.7 3.7e-16 58.7 0.7 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAG06284.1 - 2.9e-11 42.9 0.4 5e-11 42.1 0.4 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG06284.1 - 7.1e-11 41.5 3.3 8.4e-11 41.2 1.3 2.2 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG06284.1 - 3.5e-07 30.3 1.2 5.9e-07 29.6 1.2 1.3 1 1 0 1 1 1 1 ECF sigma factor Aminotran_1_2 PF00155.21 AAG06285.1 - 1.1e-28 100.5 0.0 1.8e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAG06285.1 - 1.2e-19 69.7 0.2 3.6e-19 68.2 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 AAG06285.1 - 0.00016 20.6 0.0 0.00036 19.4 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Fe_dep_repress PF01325.19 AAG06285.1 - 0.00078 19.6 0.1 0.0024 18.0 0.0 1.9 2 0 0 2 2 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 AAG06285.1 - 0.0073 16.2 0.1 0.026 14.4 0.1 2.0 1 0 0 1 1 1 1 MarR family HTH_50 PF18024.1 AAG06285.1 - 0.0081 15.7 0.1 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AAG06285.1 - 0.012 15.6 0.0 0.052 13.5 0.0 2.1 2 0 0 2 2 2 0 HTH domain HTH_24 PF13412.6 AAG06285.1 - 0.012 15.2 0.0 0.042 13.4 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAG06285.1 - 0.02 14.8 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_41 PF14502.6 AAG06285.1 - 0.028 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG06285.1 - 0.03 14.3 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAG06285.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_36 PF13730.6 AAG06285.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.19 AAG06287.1 - 2.2e-14 52.7 0.1 4.4e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAG06287.1 - 9.5e-12 45.1 0.0 2.7e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain HTH_38 PF13936.6 AAG06287.1 - 4.2e-05 23.2 0.1 7.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG06287.1 - 0.00058 19.7 0.2 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAG06287.1 - 0.0047 16.9 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAG06287.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_5 PF01022.20 AAG06287.1 - 0.032 14.1 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 AAG06287.1 - 0.042 13.7 0.1 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 AAG06287.1 - 0.055 13.6 0.1 0.17 12.1 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 AAG06287.1 - 0.093 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix OmpA PF00691.20 AAG06288.1 - 2.3e-23 82.4 0.2 6.6e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 OmpA family DUF4398 PF14346.6 AAG06288.1 - 6.8e-10 39.4 1.3 6.8e-10 39.4 1.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4398) Pilus_CpaD PF09476.10 AAG06288.1 - 0.048 13.4 2.4 0.62 9.8 0.1 2.3 1 1 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) FlpD PF02662.16 AAG06288.1 - 0.14 12.2 0.1 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit DivIC PF04977.15 AAG06288.1 - 8.2 6.3 8.2 20 5.1 5.1 2.8 2 1 1 3 3 3 0 Septum formation initiator DUF4398 PF14346.6 AAG06289.1 - 4.2e-11 43.3 17.8 5.5e-11 42.9 17.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) Alkyl_sulf_dimr PF14863.6 AAG06289.1 - 0.042 14.3 2.6 0.053 14.0 2.6 1.1 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Rbsn PF11464.8 AAG06289.1 - 0.092 12.5 0.8 0.092 12.5 0.8 2.3 3 0 0 3 3 3 0 Rabenosyn Rab binding domain SpoU_methylase PF00588.19 AAG06289.1 - 0.13 12.4 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 SpoU rRNA Methylase family SBP_bac_3 PF00497.20 AAG06290.1 - 4.3e-17 62.3 0.0 5.2e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAG06290.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein TP_methylase PF00590.20 AAG06291.1 - 4.9e-33 114.9 1.0 4.9e-33 114.9 1.0 2.1 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiG_N PF11760.8 AAG06291.1 - 2.2e-23 82.1 1.1 6.3e-23 80.6 0.1 2.4 3 0 0 3 3 3 1 Cobalamin synthesis G N-terminal TP_methylase PF00590.20 AAG06292.1 - 2.1e-47 161.8 0.4 2.5e-47 161.6 0.4 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases VPS13_C PF16909.5 AAG06292.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal CbiC PF02570.15 AAG06293.1 - 3.9e-73 245.3 0.8 4.4e-73 245.1 0.8 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase NIR_SIR_ferr PF03460.17 AAG06294.1 - 1.6e-28 98.4 0.2 1.2e-14 53.9 0.0 2.3 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain NIR_SIR PF01077.22 AAG06294.1 - 1.2e-14 54.2 0.0 3e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain TP_methylase PF00590.20 AAG06295.1 - 1.5e-17 64.3 1.0 6.9e-17 62.1 1.0 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PCMT PF01135.19 AAG06295.1 - 0.0049 16.7 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 AAG06295.1 - 0.0049 17.5 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AAG06295.1 - 0.0095 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.6 AAG06295.1 - 0.015 16.3 0.0 0.052 14.6 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 AAG06295.1 - 0.016 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 AAG06295.1 - 0.2 11.2 0.0 0.63 9.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain CbiD PF01888.17 AAG06296.1 - 2.9e-89 298.7 0.1 4.1e-89 298.2 0.1 1.2 1 0 0 1 1 1 1 CbiD CbiJ PF02571.14 AAG06297.1 - 3.4e-56 190.4 0.0 3.8e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK Mntp PF02659.15 AAG06298.1 - 5.8e-53 178.7 17.6 1.1e-52 177.8 11.7 2.0 2 0 0 2 2 2 2 Putative manganese efflux pump DUF4870 PF09685.10 AAG06298.1 - 6.8 6.8 8.7 1.5e+02 2.5 8.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4870) TonB_dep_Rec PF00593.24 AAG06299.1 - 2.1e-54 186.2 28.1 2.1e-54 186.2 28.1 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG06299.1 - 1.4e-20 73.9 1.0 2.7e-20 72.9 1.0 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain ABC_tran PF00005.27 AAG06300.1 - 2.2e-29 102.7 0.0 2.8e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06300.1 - 9.3e-14 51.9 0.7 2.5e-06 27.5 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG06300.1 - 2.2e-07 31.4 2.0 4.1e-06 27.3 0.8 2.4 1 1 1 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AAG06300.1 - 8e-05 22.2 0.0 0.05 13.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAG06300.1 - 0.00078 19.3 0.1 0.21 11.3 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AAG06300.1 - 0.0012 19.1 0.7 0.05 13.9 0.7 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AAG06300.1 - 0.0016 18.7 0.0 0.023 14.9 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 AAG06300.1 - 0.0036 16.6 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.6 AAG06300.1 - 0.0085 16.6 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAG06300.1 - 0.027 14.0 0.9 0.13 11.8 0.4 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAG06300.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AAG06300.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAG06300.1 - 0.16 12.3 0.0 0.54 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AAG06300.1 - 0.2 12.1 0.0 0.43 11.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peripla_BP_2 PF01497.18 AAG06301.1 - 9.1e-24 84.3 0.0 1.2e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Replic_Relax PF13814.6 AAG06301.1 - 0.054 13.5 0.0 0.32 11.0 0.0 2.0 2 1 0 2 2 2 0 Replication-relaxation FecCD PF01032.18 AAG06302.1 - 2.6e-86 289.5 39.1 3.2e-86 289.2 39.1 1.1 1 0 0 1 1 1 1 FecCD transport family DUF3021 PF11457.8 AAG06302.1 - 4.7 7.6 8.3 28 5.1 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Lactamase_B PF00753.27 AAG06303.1 - 3.9e-21 76.0 0.2 5.7e-21 75.4 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG06303.1 - 0.00035 20.1 0.5 0.0006 19.4 0.2 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain LysE PF01810.18 AAG06304.1 - 7.8e-19 67.9 14.3 9.2e-19 67.7 14.3 1.1 1 0 0 1 1 1 1 LysE type translocator AraC_binding PF02311.19 AAG06305.1 - 5.6e-31 107.2 1.3 8.6e-31 106.6 1.3 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_18 PF12833.7 AAG06305.1 - 1.1e-20 73.7 0.9 3.5e-20 72.1 0.9 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06305.1 - 2.7e-14 52.8 0.0 2.5e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family ROS_MUCR PF05443.11 AAG06305.1 - 0.084 12.9 0.1 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein adh_short_C2 PF13561.6 AAG06306.1 - 5.8e-39 134.0 1.7 6.8e-39 133.8 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06306.1 - 1.5e-32 112.6 1.9 2.5e-32 111.9 1.7 1.4 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 AAG06306.1 - 7.4e-13 48.8 0.9 9.4e-13 48.5 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG06306.1 - 0.00035 20.1 0.5 0.0053 16.3 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAG06306.1 - 0.16 11.3 0.2 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF2157 PF09925.9 AAG06307.1 - 5.7 6.7 13.5 6.8 6.5 13.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) MCPsignal PF00015.21 AAG06308.1 - 3.6e-42 144.1 32.2 2.2e-40 138.3 25.4 2.8 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAG06308.1 - 2.9e-12 46.5 4.9 1.2e-11 44.5 0.0 3.4 3 1 1 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAG06308.1 - 1.8e-11 44.2 0.5 1.8e-11 44.2 0.5 5.2 7 1 0 7 7 6 1 HAMP domain TarH PF02203.15 AAG06308.1 - 9.1e-06 25.7 3.9 9.1e-06 25.7 3.9 3.8 2 1 1 3 3 2 1 Tar ligand binding domain homologue DUF948 PF06103.11 AAG06308.1 - 0.00039 20.6 15.9 2.7 8.3 0.7 5.2 2 1 2 4 4 4 3 Bacterial protein of unknown function (DUF948) GAT PF03127.14 AAG06308.1 - 0.0082 16.4 1.8 0.41 11.0 0.4 3.9 4 0 0 4 4 4 1 GAT domain Laminin_II PF06009.12 AAG06308.1 - 0.012 15.7 18.8 0.023 14.7 2.8 3.4 2 1 0 2 2 2 0 Laminin Domain II TMF_DNA_bd PF12329.8 AAG06308.1 - 0.017 15.1 1.6 0.67 10.0 0.1 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 AAG06308.1 - 0.041 14.1 6.4 0.076 13.2 1.3 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Wzy_C_2 PF11846.8 AAG06308.1 - 0.051 13.5 0.8 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF4279 PF14106.6 AAG06308.1 - 0.071 13.3 0.0 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) BLOC1_2 PF10046.9 AAG06308.1 - 0.072 13.4 10.0 0.19 12.0 1.1 4.6 5 1 2 7 7 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WXG100 PF06013.12 AAG06308.1 - 0.32 11.2 29.2 0.25 11.6 0.6 7.2 6 2 1 8 8 8 0 Proteins of 100 residues with WXG zf-C4H2 PF10146.9 AAG06308.1 - 0.43 10.9 1.9 6.6 7.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger-containing protein Serine_rich PF08824.10 AAG06308.1 - 0.48 10.4 11.6 0.18 11.8 3.4 3.3 3 1 1 4 4 4 0 Serine rich protein interaction domain APG6_N PF17675.1 AAG06308.1 - 3 8.4 17.4 1.9 9.0 2.2 4.2 5 1 0 5 5 5 0 Apg6 coiled-coil region GldM_N PF12081.8 AAG06308.1 - 4.4 7.4 9.2 4 7.5 3.5 2.7 2 1 1 3 3 2 0 GldM N-terminal domain DUF16 PF01519.16 AAG06308.1 - 4.6 7.8 5.3 16 6.0 1.6 3.1 2 1 1 3 3 3 0 Protein of unknown function DUF16 Sec20 PF03908.13 AAG06308.1 - 7.2 6.6 6.5 1.1 9.2 0.5 2.8 3 0 0 3 3 3 0 Sec20 HAUS6_N PF14661.6 AAG06308.1 - 8.3 5.9 14.7 1.6 8.3 4.9 3.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus LysR_substrate PF03466.20 AAG06309.1 - 3e-31 108.4 5.1 4.5e-31 107.8 5.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06309.1 - 1.1e-16 60.5 1.8 2.9e-16 59.1 1.8 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG06309.1 - 0.0017 18.2 0.3 0.0043 16.9 0.3 1.8 1 0 0 1 1 1 1 MarR family HTH_29 PF13551.6 AAG06309.1 - 0.0026 17.8 0.0 0.0073 16.3 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_50 PF18024.1 AAG06309.1 - 0.0061 16.1 0.2 0.016 14.8 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG06309.1 - 0.01 15.6 0.1 0.031 14.1 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 AAG06309.1 - 0.015 14.9 0.1 0.043 13.4 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAG06309.1 - 0.017 15.2 0.3 0.045 13.9 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AAG06309.1 - 0.044 13.7 1.6 0.065 13.2 0.0 2.1 2 0 0 2 2 2 0 MarR family FokI_N PF02981.15 AAG06309.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain P22_Cro PF14549.6 AAG06309.1 - 0.1 12.4 0.5 0.24 11.3 0.5 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_6 PF01418.17 AAG06309.1 - 0.12 12.4 0.1 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 AAG06309.1 - 0.14 12.0 2.6 0.27 11.1 0.6 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain Peptidase_M20 PF01546.28 AAG06310.1 - 6.6e-35 120.7 0.1 9.6e-35 120.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAG06310.1 - 1.3e-08 34.8 0.0 2.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain SBP_bac_3 PF00497.20 AAG06311.1 - 2e-57 194.2 0.0 2.3e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG06311.1 - 1e-07 32.1 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAG06311.1 - 0.00048 20.1 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 NMT1/THI5 like YhfZ_C PF14503.6 AAG06311.1 - 0.042 13.4 0.0 0.69 9.4 0.0 2.0 1 1 1 2 2 2 0 YhfZ C-terminal domain BPD_transp_1 PF00528.22 AAG06312.1 - 3.2e-26 92.2 8.8 3.2e-26 92.2 8.8 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG06313.1 - 2e-12 47.2 10.5 2e-12 47.2 10.5 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3368 PF11848.8 AAG06313.1 - 0.039 13.7 1.4 5.6 6.8 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) ABC_tran PF00005.27 AAG06314.1 - 1.3e-31 109.9 0.0 1.8e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06314.1 - 9.5e-11 42.0 0.0 9.5e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG06314.1 - 8.7e-07 28.6 0.9 0.0015 18.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG06314.1 - 0.002 17.9 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 AAG06314.1 - 0.0035 16.4 0.0 0.0091 15.0 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_ATPase PF09818.9 AAG06314.1 - 0.0059 15.5 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_33 PF13671.6 AAG06314.1 - 0.0086 16.2 0.0 0.02 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG06314.1 - 0.014 15.8 1.0 0.038 14.4 1.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AAG06314.1 - 0.046 13.3 0.1 0.15 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAG06314.1 - 0.055 14.0 0.0 0.084 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 AAG06314.1 - 0.055 13.2 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_13 PF13166.6 AAG06314.1 - 0.12 11.0 0.0 0.53 8.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AAG06314.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 AAG06314.1 - 0.16 12.2 0.6 0.53 10.6 0.1 1.9 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAG06314.1 - 0.17 12.1 0.1 1.9 8.8 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AAG06314.1 - 0.19 11.6 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 AAG06314.1 - 0.29 10.8 0.2 4.3 6.9 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Palm_thioest PF02089.15 AAG06315.1 - 0.00029 20.8 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 AAG06315.1 - 0.0058 16.5 0.1 0.0097 15.8 0.1 1.3 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 AAG06315.1 - 0.058 12.6 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAG06315.1 - 0.5 10.9 16.9 4.4 7.8 16.9 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family LysE PF01810.18 AAG06317.1 - 8.3e-30 103.7 11.7 9.6e-30 103.5 11.7 1.0 1 0 0 1 1 1 1 LysE type translocator LHC PF00556.20 AAG06317.1 - 0.32 11.2 0.3 0.32 11.2 0.3 3.1 4 0 0 4 4 4 0 Antenna complex alpha/beta subunit TerC PF03741.16 AAG06317.1 - 1.1 8.9 6.5 2.6 7.7 6.4 1.8 1 1 0 1 1 1 0 Integral membrane protein TerC family LysR_substrate PF03466.20 AAG06318.1 - 1e-19 70.7 5.4 1.6e-19 70.1 5.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06318.1 - 2.4e-19 69.0 1.9 5.3e-19 67.9 1.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG06318.1 - 0.071 13.0 0.5 0.53 10.2 0.3 2.4 2 0 0 2 2 2 0 MarR family TetR_N PF00440.23 AAG06319.1 - 4.9e-10 39.0 0.1 9.4e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAG06319.1 - 1.8e-05 24.9 4.7 1.8e-05 24.9 4.7 2.0 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_11 PF16859.5 AAG06319.1 - 5.7e-05 23.4 4.7 5.7e-05 23.4 4.7 2.0 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain RHH_1 PF01402.21 AAG06319.1 - 0.037 14.0 2.7 4.5 7.4 0.0 3.4 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family TetR_C_13 PF16925.5 AAG06319.1 - 0.042 13.8 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PSK_trans_fac PF07704.11 AAG06319.1 - 0.58 10.9 5.0 0.31 11.8 0.5 2.8 3 1 0 3 3 3 0 Rv0623-like transcription factor Oxidored_FMN PF00724.20 AAG06320.1 - 2.2e-90 303.4 0.0 2.5e-90 303.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 AAG06320.1 - 0.0018 17.4 0.0 0.0098 15.0 0.0 2.1 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) MFS_1 PF07690.16 AAG06321.1 - 1.5e-37 129.4 95.3 6.3e-33 114.2 59.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG06321.1 - 7.5e-06 25.5 48.4 0.00042 19.7 49.3 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAG06321.1 - 0.24 10.2 23.8 0.25 10.1 7.3 2.4 1 1 1 2 2 2 0 MFS_1 like family Abhydrolase_6 PF12697.7 AAG06322.1 - 1.5e-18 68.2 1.4 2.4e-18 67.5 1.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG06322.1 - 2.7e-14 53.5 0.0 1.3e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06322.1 - 6.8e-05 22.2 0.0 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ni_hydr_CYTB PF01292.20 AAG06324.1 - 2.9e-25 88.9 14.1 3.3e-25 88.7 14.1 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4191 PF13829.6 AAG06324.1 - 0.2 10.9 2.4 6.2 6.1 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Xan_ur_permease PF00860.20 AAG06326.1 - 6.4e-90 301.7 54.0 8.4e-90 301.3 54.0 1.1 1 0 0 1 1 1 1 Permease family Peptidase_M28 PF04389.17 AAG06327.1 - 6.8e-46 156.5 0.0 1e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 AAG06327.1 - 1.6e-16 60.1 1.0 3.3e-16 59.1 1.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 AAG06327.1 - 8.4e-05 22.4 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Thiolase_N PF00108.23 AAG06328.1 - 6.1e-60 202.8 0.8 1.2e-59 201.8 0.1 1.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG06328.1 - 4e-45 152.4 2.9 7.1e-45 151.6 2.9 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain VWA_2 PF13519.6 AAG06329.1 - 2.6e-09 37.7 0.0 3.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 AAG06329.1 - 4.2e-06 26.8 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 AAG06329.1 - 2.4e-05 24.7 0.0 3.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_lid_2 PF17863.1 AAG06330.1 - 5.2e-16 58.2 4.0 1.2e-15 57.1 3.8 1.7 1 1 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAG06330.1 - 1.8e-12 47.4 0.0 2.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG06330.1 - 4.8e-10 39.2 0.3 8.1e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 AAG06330.1 - 2.2e-08 33.5 0.0 3.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AAG06330.1 - 5.6e-06 26.2 0.0 8.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 AAG06330.1 - 0.0033 17.8 0.0 0.0069 16.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG06330.1 - 0.01 16.2 1.7 0.02 15.3 1.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 AAG06330.1 - 0.021 14.6 0.0 7.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 AAG06330.1 - 0.031 14.4 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AAG06330.1 - 0.062 13.2 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAG06330.1 - 0.071 13.4 0.1 2.2 8.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain DAHP_synth_1 PF00793.20 AAG06331.1 - 1.3e-78 263.7 0.0 1.6e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CobN-Mg_chel PF02514.16 AAG06332.1 - 0 1339.3 0.0 0 1339.1 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Glyco_transf_4 PF13439.6 AAG06332.1 - 4.7 7.2 5.7 6 6.8 0.0 3.5 4 0 0 4 4 4 0 Glycosyltransferase Family 4 cobW PF02492.19 AAG06333.1 - 5.4e-59 198.7 0.0 7.3e-59 198.3 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAG06333.1 - 1.2e-17 63.6 0.2 2.8e-17 62.4 0.2 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 AAG06333.1 - 0.0049 17.1 0.7 0.035 14.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AAG06333.1 - 0.0065 16.9 2.6 0.0099 16.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 AAG06333.1 - 0.007 15.3 0.3 0.011 14.6 0.1 1.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 AAG06333.1 - 0.02 13.9 0.4 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 AAG06333.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 AAG06333.1 - 0.041 13.9 0.0 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AAG06333.1 - 0.047 13.4 0.3 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAG06333.1 - 0.065 13.4 0.1 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAG06333.1 - 0.25 11.2 0.0 0.48 10.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 AAG06333.1 - 0.56 10.1 0.0 0.56 10.1 0.0 2.6 3 2 1 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B CbtA PF09490.10 AAG06334.1 - 5.2e-67 226.1 27.6 8e-67 225.5 27.6 1.3 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) CbiG_C PF01890.16 AAG06335.1 - 2.9e-27 95.5 0.0 3.3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus TP_methylase PF00590.20 AAG06336.1 - 2.6e-48 164.8 1.1 3.1e-48 164.5 1.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 AAG06336.1 - 0.0016 18.9 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Abhydrolase_1 PF00561.20 AAG06337.1 - 7e-29 101.2 0.0 3.7e-23 82.5 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG06337.1 - 6e-28 99.0 1.2 7.7e-28 98.6 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG06337.1 - 1.4e-15 57.2 0.0 3.6e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAG06337.1 - 3.6e-07 29.2 0.0 0.018 13.7 0.0 2.1 2 0 0 2 2 2 2 Ndr family Esterase PF00756.20 AAG06337.1 - 0.003 17.3 0.3 0.0067 16.1 0.2 1.6 1 1 0 1 1 1 1 Putative esterase DUF2048 PF09752.9 AAG06337.1 - 0.0064 15.6 0.0 0.015 14.4 0.0 1.5 2 0 0 2 2 2 1 Abhydrolase domain containing 18 Abhydrolase_5 PF12695.7 AAG06337.1 - 0.0079 16.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 AAG06337.1 - 0.037 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 AAG06337.1 - 0.04 14.0 0.1 0.045 13.9 0.1 1.4 1 1 0 1 1 1 0 Thioesterase domain DUF2920 PF11144.8 AAG06337.1 - 0.28 10.3 0.0 8.4 5.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) LPAM_1 PF08139.12 AAG06337.1 - 0.58 10.8 4.3 1.5 9.4 4.3 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Enoyl_reductase PF12241.8 AAG06338.1 - 2.3e-107 357.7 0.0 2.7e-107 357.5 0.0 1.1 1 0 0 1 1 1 1 Trans-2-enoyl-CoA reductase catalytic region Eno-Rase_NADH_b PF12242.8 AAG06338.1 - 6.4e-38 128.4 0.1 1.5e-37 127.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Eno-Rase_FAD_bd PF07055.12 AAG06338.1 - 1.5e-29 102.2 1.1 2.8e-29 101.3 1.1 1.5 1 0 0 1 1 1 1 Enoyl reductase FAD binding domain ETF PF01012.21 AAG06339.1 - 1.4e-39 135.9 14.5 2.5e-39 135.1 14.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 AAG06339.1 - 7.2e-37 125.3 0.9 7.2e-37 125.3 0.9 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain FLgD_tudor PF13861.6 AAG06339.1 - 0.99 9.7 5.2 0.57 10.5 1.0 2.4 2 0 0 2 2 2 0 FlgD Tudor-like domain ETF PF01012.21 AAG06340.1 - 2.4e-46 157.9 5.8 3.9e-46 157.2 5.8 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ala_racemase_N PF01168.20 AAG06340.1 - 0.0017 18.0 0.8 0.0017 18.0 0.8 1.5 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain ETF_QO PF05187.13 AAG06341.1 - 1.3e-50 169.9 0.1 2.1e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 AAG06341.1 - 2.4e-10 40.5 1.5 6e-05 22.8 1.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG06341.1 - 1.2e-09 37.8 0.5 1.4e-05 24.3 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 AAG06341.1 - 1.2e-07 31.9 0.0 7.1e-07 29.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAG06341.1 - 1.3e-07 31.1 0.0 1.3e-06 27.9 0.2 2.0 1 1 1 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 AAG06341.1 - 3.8e-05 23.1 0.0 0.00046 19.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAG06341.1 - 5.5e-05 22.5 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAG06341.1 - 5.9e-05 22.3 1.1 9.3e-05 21.6 1.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAG06341.1 - 0.00014 21.9 0.1 0.00031 20.8 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 AAG06341.1 - 0.00036 19.4 1.1 0.00052 18.8 1.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 AAG06341.1 - 0.00065 19.1 0.9 0.00095 18.5 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG06341.1 - 0.005 16.2 0.2 0.0079 15.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAG06341.1 - 0.0066 17.0 0.4 1.1 9.9 0.5 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AAG06341.1 - 0.011 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 AAG06341.1 - 0.035 13.2 1.6 0.32 10.0 1.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Fer4_7 PF12838.7 AAG06341.1 - 0.061 13.9 1.6 0.13 12.8 1.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 AAG06341.1 - 0.094 11.5 0.4 0.19 10.6 0.5 1.4 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_2 PF12797.7 AAG06341.1 - 0.13 12.4 0.6 0.36 11.0 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain DUF1285 PF06938.11 AAG06342.1 - 3.2e-60 202.4 0.0 3.8e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1285) DUF4823 PF16105.5 AAG06343.1 - 3.9e-60 201.8 0.0 5.5e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4823) Radical_SAM PF04055.21 AAG06344.1 - 1.5e-18 67.8 0.0 2.3e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TetR_N PF00440.23 AAG06345.1 - 4.5e-16 58.4 0.1 9.2e-16 57.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 AAG06345.1 - 6.8e-08 33.2 0.2 1.6e-07 32.0 0.2 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_40 PF14493.6 AAG06345.1 - 0.054 14.0 0.1 0.1 13.0 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAG06345.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain Aminotran_5 PF00266.19 AAG06346.1 - 1.3e-50 172.4 0.0 1.6e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V TatD_DNase PF01026.21 AAG06347.1 - 1.6e-77 260.3 0.0 1.9e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase PilZ PF07238.14 AAG06348.1 - 2.1e-13 50.4 0.0 2.6e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 PilZ domain DNA_pol3_delta2 PF13177.6 AAG06349.1 - 1.4e-45 155.0 0.0 2.2e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNApol3-delta_C PF09115.10 AAG06349.1 - 2.9e-08 34.2 3.7 5e-08 33.5 3.1 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit, C terminal AAA PF00004.29 AAG06349.1 - 0.00013 22.4 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG06349.1 - 0.00058 20.3 0.4 0.0017 18.8 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AAG06349.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 AAG06350.1 - 3.6e-48 163.7 0.0 4e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 AAG06350.1 - 8.5e-06 26.1 0.2 1.1e-05 25.7 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG06350.1 - 0.0027 18.0 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAG06350.1 - 0.024 14.8 0.0 0.047 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAG06350.1 - 0.048 13.7 0.0 0.099 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Type_III_YscX PF09474.10 AAG06350.1 - 0.048 13.9 0.1 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) AAA_18 PF13238.6 AAG06350.1 - 0.1 13.1 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAG06350.1 - 0.15 12.4 3.2 0.77 10.1 3.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 AAG06350.1 - 0.21 10.5 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB YceG PF02618.16 AAG06351.1 - 1.1e-78 264.6 0.0 1.3e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 YceG-like family Aminotran_4 PF01063.19 AAG06352.1 - 2.1e-48 165.1 0.0 2.4e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV ketoacyl-synt PF00109.26 AAG06353.1 - 5.6e-62 209.6 0.9 1.2e-60 205.2 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAG06353.1 - 1.3e-41 141.3 0.3 2.3e-41 140.5 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AAG06353.1 - 2.6e-05 23.7 2.0 0.00035 20.0 0.4 2.5 3 0 0 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 AAG06353.1 - 0.23 11.4 3.9 3.1 7.7 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Keratin_2_head PF16208.5 AAG06353.1 - 0.77 9.9 8.9 0.33 11.1 5.7 2.0 2 0 0 2 2 2 0 Keratin type II head PP-binding PF00550.25 AAG06354.1 - 2.6e-17 62.9 0.3 2.9e-17 62.8 0.3 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 AAG06354.1 - 4.3e-08 33.3 1.3 6.1e-08 32.8 1.3 1.3 1 1 0 1 1 1 1 Acyl-carrier HLH PF00010.26 AAG06354.1 - 0.0068 16.3 0.0 0.0068 16.3 0.0 1.3 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L50 PF10501.9 AAG06354.1 - 0.0076 16.4 0.1 0.011 15.9 0.1 1.5 1 1 0 1 1 1 1 Ribosomal subunit 39S DUF1493 PF07377.12 AAG06354.1 - 0.015 15.7 0.5 0.016 15.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1896 PF08989.10 AAG06354.1 - 0.02 15.0 0.1 0.022 14.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) adh_short_C2 PF13561.6 AAG06355.1 - 2.1e-63 214.0 4.8 2.4e-63 213.8 4.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06355.1 - 2.3e-56 190.3 2.5 2.9e-56 190.1 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG06355.1 - 2.1e-18 66.9 2.5 2.8e-18 66.4 2.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG06355.1 - 0.001 18.6 0.4 0.0032 16.9 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAG06355.1 - 0.0017 17.7 0.0 0.15 11.4 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF915 PF06028.11 AAG06355.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) THF_DHG_CYH_C PF02882.19 AAG06355.1 - 0.088 12.1 1.1 0.36 10.1 0.1 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Acyl_transf_1 PF00698.21 AAG06356.1 - 3.3e-41 141.8 3.3 3.9e-41 141.6 3.3 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 AAG06356.1 - 0.037 13.8 0.5 0.17 11.6 0.1 2.3 3 0 0 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Dor1 PF04124.12 AAG06356.1 - 0.085 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family CRIM PF16978.5 AAG06356.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain BMC PF00936.19 AAG06356.1 - 2.1 8.4 8.4 2.7 8.1 6.7 2.2 2 1 0 2 2 2 0 BMC domain FA_synthesis PF02504.15 AAG06357.1 - 7.2e-93 311.2 0.0 8.1e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein PTA_PTB PF01515.19 AAG06357.1 - 3.6e-08 33.1 0.0 5.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase DUF615 PF04751.14 AAG06357.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Ribosomal_L32p PF01783.23 AAG06358.1 - 3.4e-20 72.0 0.4 3.7e-20 71.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family YceD PF02620.17 AAG06359.1 - 7.9e-19 68.0 0.3 1.1e-18 67.5 0.3 1.2 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Maf PF02545.14 AAG06360.1 - 7.9e-45 152.7 0.0 8.9e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Peptidase_S49 PF01343.18 AAG06361.1 - 1.5e-35 122.4 0.0 2.3e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 AAG06361.1 - 1.9e-05 24.6 0.1 9.7e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Clp protease SDH_sah PF01972.16 AAG06361.1 - 0.0023 17.0 0.1 0.004 16.2 0.1 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase PikAIV_N PF18605.1 AAG06361.1 - 0.16 11.6 0.8 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HAD_2 PF13419.6 AAG06362.1 - 1.3e-29 103.6 0.0 1.5e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG06362.1 - 4.8e-19 69.5 0.0 1.3e-18 68.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG06362.1 - 1.8e-13 50.3 0.0 5e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 AAG06362.1 - 4e-11 43.7 0.2 6.3e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAG06362.1 - 2.1e-05 24.4 0.0 0.38 10.4 0.0 3.0 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAG06362.1 - 0.079 13.1 0.0 0.48 10.6 0.0 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PseudoU_synth_2 PF00849.22 AAG06363.1 - 4.1e-31 108.2 0.0 5.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAG06363.1 - 1.7e-09 37.3 0.7 3e-09 36.4 0.7 1.5 1 0 0 1 1 1 1 S4 domain RNase_E_G PF10150.9 AAG06364.1 - 1.1e-95 320.1 0.0 1.1e-95 320.1 0.0 2.0 2 1 1 3 3 3 1 Ribonuclease E/G family S1 PF00575.23 AAG06364.1 - 2.9e-15 56.4 0.1 6.7e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain MurB_C PF02873.16 AAG06365.1 - 1.2e-36 125.4 0.0 2e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 AAG06365.1 - 9.2e-27 93.5 0.0 1.7e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DUF4350 PF14258.6 AAG06365.1 - 0.046 14.1 0.5 3.1 8.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) LMWPc PF01451.21 AAG06366.1 - 7.4e-41 139.8 0.0 8.3e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CTP_transf_3 PF02348.19 AAG06367.1 - 8.2e-56 189.4 0.0 1e-55 189.1 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAG06367.1 - 5e-13 49.7 1.3 5e-13 49.7 1.3 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 AAG06367.1 - 0.095 12.5 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) DUF4913 PF16259.5 AAG06367.1 - 0.17 12.0 0.5 0.3 11.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) Trm112p PF03966.16 AAG06368.1 - 1.8e-10 41.2 0.1 4.4e-10 40.0 0.1 1.6 1 1 0 1 1 1 1 Trm112p-like protein LpxK PF02606.14 AAG06369.1 - 1.6e-106 356.1 0.0 1.9e-106 355.9 0.0 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase MobB PF03205.14 AAG06369.1 - 0.001 18.9 0.0 0.0025 17.7 0.0 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Glyco_transf_4 PF13439.6 AAG06369.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ExbD PF02472.16 AAG06370.1 - 1.5e-26 93.1 0.1 1.7e-26 92.9 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR MotA_ExbB PF01618.16 AAG06371.1 - 1.9e-35 121.4 1.8 2.6e-35 121.0 1.8 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF2512 PF10710.9 AAG06371.1 - 0.34 10.5 0.1 0.34 10.5 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2512) Competence PF03772.16 AAG06372.1 - 1.3e-53 182.0 40.6 1.3e-53 182.0 40.6 1.7 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 AAG06372.1 - 3.7e-22 78.7 2.7 3.7e-22 78.7 2.7 5.2 3 1 2 5 5 5 1 Domain of unknown function (DUF4131) Lactamase_B PF00753.27 AAG06372.1 - 2.6e-18 66.8 1.1 5.8e-18 65.6 1.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG06372.1 - 0.0014 18.2 0.1 0.0044 16.6 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2062 PF09835.9 AAG06373.1 - 1.9e-50 170.5 10.2 2.3e-50 170.3 10.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) MacB_PCD PF12704.7 AAG06374.1 - 5.6e-18 66.0 0.5 5.6e-18 66.0 0.5 2.4 2 1 0 3 3 3 1 MacB-like periplasmic core domain FtsX PF02687.21 AAG06374.1 - 4.7e-16 59.0 11.3 8.6e-15 55.0 2.0 3.2 3 0 0 3 3 3 2 FtsX-like permease family McyA_C PF12593.8 AAG06374.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Microcystin synthetase C terminal SLATT_fungal PF18142.1 AAG06374.1 - 3 7.9 10.1 5.6 7.0 0.4 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain ABC_tran PF00005.27 AAG06375.1 - 7e-34 117.3 0.0 9.2e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAG06375.1 - 2e-07 30.7 0.2 0.00016 21.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAG06375.1 - 3.3e-05 23.9 3.0 0.038 13.8 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAG06375.1 - 0.00047 20.1 0.3 0.00087 19.2 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAG06375.1 - 0.00078 19.9 2.9 0.0026 18.2 2.9 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG06375.1 - 0.00093 18.9 0.2 0.0017 18.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAG06375.1 - 0.0014 18.7 0.2 0.0063 16.6 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 AAG06375.1 - 0.0061 16.8 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AAG06375.1 - 0.0099 15.8 0.9 0.36 10.7 0.1 2.2 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.6 AAG06375.1 - 0.012 15.9 0.0 0.24 11.6 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 AAG06375.1 - 0.012 15.6 0.5 0.022 14.8 0.5 1.4 1 0 0 1 1 1 0 Dynamin family DUF87 PF01935.17 AAG06375.1 - 0.023 14.8 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 AAG06375.1 - 0.034 14.4 0.5 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AAG06375.1 - 0.035 13.5 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 AAG06375.1 - 0.083 12.6 0.5 0.36 10.5 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAG06375.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAG06375.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAG06375.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 AAG06375.1 - 0.22 11.7 0.9 0.48 10.6 0.9 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAG06375.1 - 0.26 10.4 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit MacB_PCD PF12704.7 AAG06376.1 - 9.6e-17 62.0 1.7 9.6e-17 62.0 1.7 2.3 2 1 0 3 3 3 1 MacB-like periplasmic core domain FtsX PF02687.21 AAG06376.1 - 1.7e-15 57.3 13.1 6.4e-14 52.2 2.5 3.8 4 0 0 4 4 4 2 FtsX-like permease family 7tm_7 PF08395.12 AAG06376.1 - 0.075 12.2 0.9 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor PilZ PF07238.14 AAG06377.1 - 7.4e-12 45.5 0.2 2.2e-11 44.0 0.1 1.9 3 0 0 3 3 3 1 PilZ domain GDPD PF03009.17 AAG06378.1 - 6.2e-35 121.2 0.0 1.9e-34 119.6 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 AAG06378.1 - 2e-05 24.9 0.0 3.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 AAG06378.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Pyr_redox_2 PF07992.14 AAG06379.1 - 1.9e-61 207.9 0.0 2.3e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAG06379.1 - 9e-28 96.7 0.0 5.3e-27 94.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAG06379.1 - 5.7e-19 68.5 0.1 1.3e-16 60.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG06379.1 - 8.3e-09 35.1 0.0 9.6e-08 31.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG06379.1 - 2.9e-07 30.2 0.0 4.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAG06379.1 - 1.2e-06 28.0 0.0 0.019 14.2 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AAG06379.1 - 2.1e-06 26.7 0.3 0.0044 15.8 0.2 2.6 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 AAG06379.1 - 3.9e-06 27.0 0.4 0.00033 20.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AAG06379.1 - 8.5e-06 25.1 0.1 0.049 12.7 0.1 3.9 3 1 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AAG06379.1 - 0.00019 20.7 3.4 0.0072 15.4 0.6 2.5 3 0 0 3 3 3 2 FAD binding domain 3HCDH_N PF02737.18 AAG06379.1 - 0.0026 17.7 0.1 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAG06379.1 - 0.0037 16.6 0.0 0.66 9.3 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 AAG06379.1 - 0.01 15.1 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 AAG06379.1 - 0.016 14.4 0.0 0.037 13.2 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.6 AAG06379.1 - 0.054 14.0 0.0 2.8 8.5 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_3 PF01494.19 AAG06379.1 - 0.11 11.7 1.9 0.43 9.8 0.2 2.5 3 1 1 4 4 4 0 FAD binding domain DAO PF01266.24 AAG06379.1 - 9.3 5.7 7.4 1.7 8.1 0.3 2.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase NqrM PF04400.13 AAG06380.1 - 3e-14 52.5 4.2 3.7e-14 52.2 4.2 1.1 1 0 0 1 1 1 1 (Na+)-NQR maturation NqrM ROK PF00480.20 AAG06380.1 - 0.3 10.5 2.3 0.36 10.3 2.3 1.0 1 0 0 1 1 1 0 ROK family ApbE PF02424.15 AAG06381.1 - 1e-79 267.7 0.0 1.2e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.21 AAG06382.1 - 1.1e-17 64.6 0.0 1.9e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAG06382.1 - 2.1e-11 44.0 0.0 1.4e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 AAG06382.1 - 2.3e-11 43.5 0.5 3.9e-11 42.8 0.5 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAG06382.1 - 0.00098 19.1 0.6 0.0045 17.0 0.6 2.1 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AAG06382.1 - 0.0041 17.3 0.0 0.083 13.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 AAG06382.1 - 0.0089 16.2 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Rnf-Nqr PF02508.14 AAG06383.1 - 3.4e-56 189.9 13.5 3.8e-56 189.8 13.5 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein DUF2456 PF10445.9 AAG06383.1 - 0.18 11.9 2.2 7.3 6.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2456) Rnf-Nqr PF02508.14 AAG06384.1 - 8.1e-60 201.7 13.6 9.6e-60 201.5 13.6 1.1 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein FMN_bind PF04205.14 AAG06385.1 - 2.5e-13 50.4 0.0 5e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 FMN-binding domain NQR2_RnfD_RnfE PF03116.15 AAG06386.1 - 2.3e-110 368.6 24.6 2.6e-110 368.4 24.6 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family CcmD PF04995.14 AAG06386.1 - 0.28 11.3 2.3 1.5 8.9 0.0 3.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) NQRA PF05896.11 AAG06387.1 - 7.4e-112 372.9 0.0 8.9e-112 372.7 0.0 1.1 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) NQRA_SLBB PF11973.8 AAG06387.1 - 6.2e-22 78.0 0.4 1.4e-21 76.9 0.4 1.6 1 0 0 1 1 1 1 NQRA C-terminal domain RnfC_N PF13375.6 AAG06387.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 AAG06387.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme AA_permease PF00324.21 AAG06388.1 - 5.4e-116 388.0 43.0 6.3e-116 387.8 43.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG06388.1 - 9.6e-42 143.3 46.5 1.2e-41 142.9 46.5 1.0 1 0 0 1 1 1 1 Amino acid permease Gp_dh_C PF02800.20 AAG06389.1 - 3.9e-43 146.8 0.4 5.8e-43 146.2 0.4 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AAG06389.1 - 6.3e-20 71.4 0.2 2.2e-19 69.7 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TRCF PF03461.15 AAG06390.1 - 9.6e-28 96.4 0.0 7.3e-27 93.6 0.0 2.5 3 0 0 3 3 3 1 TRCF domain CarD_CdnL_TRCF PF02559.16 AAG06390.1 - 2e-24 86.1 0.0 4.2e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 CarD-like/TRCF domain UvrB_inter PF17757.1 AAG06390.1 - 3.4e-22 78.4 0.0 7.3e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 AAG06390.1 - 5.8e-19 68.5 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG06390.1 - 2.3e-17 63.4 0.2 4.6e-16 59.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAG06390.1 - 3.1e-10 40.3 0.0 5.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AroM PF07302.11 AAG06390.1 - 0.00013 21.4 0.0 0.00032 20.1 0.0 1.6 1 0 0 1 1 1 1 AroM protein SNF2_N PF00176.23 AAG06390.1 - 0.00038 19.3 0.0 0.00052 18.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain UB2H PF14814.6 AAG06390.1 - 0.0027 17.7 0.0 0.0084 16.1 0.0 1.8 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain ERCC3_RAD25_C PF16203.5 AAG06390.1 - 0.0089 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 AAG06390.1 - 0.073 12.8 0.4 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAG06390.1 - 0.082 13.2 0.5 0.63 10.3 0.5 2.4 1 1 0 1 1 1 0 AAA domain CsiV PF10972.8 AAG06391.1 - 4.3e-25 88.9 0.0 5.2e-19 69.0 0.1 3.0 1 1 1 2 2 2 2 Peptidoglycan-binding protein, CsiV PNP_UDP_1 PF01048.20 AAG06392.1 - 2.3e-41 141.6 0.4 2.5e-41 141.5 0.4 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF5613 PF18467.1 AAG06392.1 - 0.16 12.4 0.0 3 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5613) Glyco_hydro_3 PF00933.21 AAG06393.1 - 9.5e-78 261.8 0.0 1.2e-77 261.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain TetR_C_30 PF17939.1 AAG06394.1 - 2.3e-28 98.7 0.6 4.3e-28 97.9 0.4 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAG06394.1 - 1.2e-15 57.1 0.7 2.3e-15 56.1 0.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LexA_DNA_bind PF01726.16 AAG06395.1 - 1.3e-31 108.1 0.0 2e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 AAG06395.1 - 5.6e-15 55.0 0.0 1.1e-14 54.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase S24-like HTH_20 PF12840.7 AAG06395.1 - 0.0032 17.5 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG06395.1 - 0.0041 17.0 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.16 AAG06395.1 - 0.017 14.6 0.0 0.21 11.1 0.0 2.5 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AAG06395.1 - 0.021 14.8 0.0 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAG06395.1 - 0.14 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator SulA PF03846.14 AAG06396.1 - 1.7e-08 34.4 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Cell division inhibitor SulA DUF562 PF04763.12 AAG06396.1 - 0.0024 17.3 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF562) Topoisom_bac PF01131.20 AAG06399.1 - 1.8e-128 429.1 0.0 2.5e-128 428.6 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Topo_Zn_Ribbon PF08272.11 AAG06399.1 - 1.8e-34 117.1 0.2 5.4e-20 70.8 1.0 2.7 2 0 0 2 2 2 2 Topoisomerase I zinc-ribbon-like Toprim PF01751.22 AAG06399.1 - 8.6e-33 112.7 0.0 2e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 AAG06399.1 - 1.6e-16 59.8 21.3 1.4e-11 43.9 4.4 4.2 4 1 0 4 4 4 3 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.6 AAG06399.1 - 0.0045 17.5 6.2 0.16 12.5 0.0 3.7 3 0 0 3 3 3 1 Recombinase zinc beta ribbon domain Toprim_4 PF13662.6 AAG06399.1 - 0.028 14.9 0.0 0.34 11.4 0.0 2.7 3 1 0 3 3 3 0 Toprim domain Toprim_2 PF13155.6 AAG06399.1 - 0.11 13.0 0.0 0.78 10.2 0.0 2.3 2 0 0 2 2 2 0 Toprim-like TF_Zn_Ribbon PF08271.12 AAG06399.1 - 2.9 7.5 7.8 1.6 8.3 0.4 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding DUF1653 PF07866.11 AAG06400.1 - 3.9e-30 103.9 0.1 5.2e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1653) Thiolase_N PF00108.23 AAG06401.1 - 1.5e-84 283.4 0.3 2.1e-84 282.9 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG06401.1 - 1.2e-47 160.6 0.4 1.2e-47 160.6 0.5 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG06401.1 - 2.5e-05 24.0 2.3 6.7e-05 22.6 1.6 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AAG06401.1 - 0.029 14.2 0.6 0.38 10.6 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3HCDH_N PF02737.18 AAG06402.1 - 1.5e-61 207.5 0.3 3.1e-61 206.4 0.3 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 AAG06402.1 - 4.5e-40 137.6 0.8 9e-40 136.6 0.8 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 AAG06402.1 - 9.6e-29 99.9 2.2 5.2e-25 87.9 0.3 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 AAG06402.1 - 2.6e-22 79.8 0.1 4e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 AAG06402.1 - 0.042 14.0 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SecA_SW PF07516.13 AAG06403.1 - 0.013 15.6 0.1 0.028 14.5 0.0 1.5 1 1 1 2 2 2 0 SecA Wing and Scaffold domain DUF2795 PF11387.8 AAG06404.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) Usp PF00582.26 AAG06405.1 - 1.3e-33 116.5 0.3 1.5e-33 116.3 0.3 1.0 1 0 0 1 1 1 1 Universal stress protein family TPR_6 PF13174.6 AAG06405.1 - 0.021 15.4 0.3 0.047 14.4 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PEP-utilizers PF00391.23 AAG06405.1 - 0.039 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain ABC_tran PF00005.27 AAG06407.1 - 6.8e-49 165.9 0.1 9e-24 84.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_CTD PF16326.5 AAG06407.1 - 8.8e-19 67.5 7.8 8.8e-19 67.5 7.8 2.7 3 0 0 3 3 2 1 ABC transporter C-terminal domain AAA_21 PF13304.6 AAG06407.1 - 1.4e-14 54.6 11.1 0.0072 16.2 0.7 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 AAG06407.1 - 3.3e-10 39.8 2.2 3.3e-10 39.8 2.2 2.9 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 AAG06407.1 - 2e-06 27.4 2.1 0.019 14.4 0.1 3.5 3 1 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG06407.1 - 4.6e-05 23.1 0.3 0.16 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG06407.1 - 7.7e-05 22.7 0.1 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 AAG06407.1 - 9.6e-05 22.4 0.0 0.57 10.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase MeaB PF03308.16 AAG06407.1 - 0.00018 20.6 0.5 0.54 9.2 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 AAG06407.1 - 0.00052 19.7 0.0 0.93 9.1 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 AAG06407.1 - 0.00075 19.9 0.0 0.84 10.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG06407.1 - 0.0011 19.4 11.4 0.036 14.5 0.2 3.5 3 1 1 4 4 4 2 AAA ATPase domain AAA_24 PF13479.6 AAG06407.1 - 0.0019 17.9 0.1 0.8 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AAG06407.1 - 0.0023 18.5 1.5 0.68 10.5 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 AAG06407.1 - 0.0044 17.3 4.5 0.82 9.9 0.2 3.6 2 2 0 2 2 2 1 AAA domain NACHT PF05729.12 AAG06407.1 - 0.0047 16.9 0.1 1.3 8.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 AAG06407.1 - 0.0048 16.7 0.1 2.6 7.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 AAG06407.1 - 0.0059 16.8 0.3 3.7 7.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 AAG06407.1 - 0.0074 15.5 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 AAG06407.1 - 0.0081 15.7 0.2 2.2 7.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_13 PF13166.6 AAG06407.1 - 0.011 14.5 0.5 4 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 AAG06407.1 - 0.014 15.7 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 AAG06407.1 - 0.018 14.7 2.2 4.1 7.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 AAG06407.1 - 0.032 14.0 1.1 6.4 6.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 AAG06407.1 - 0.04 14.4 8.8 1.8 9.0 0.0 3.7 4 0 0 4 4 3 0 AAA domain MobB PF03205.14 AAG06407.1 - 0.075 12.9 1.1 0.63 9.9 0.1 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 AAG06407.1 - 0.099 12.2 2.1 2.2 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 AAG06407.1 - 0.1 12.6 3.0 10 6.1 0.3 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAG06407.1 - 0.12 12.5 1.2 3.5 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 AAG06407.1 - 0.14 12.2 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 AAG06407.1 - 0.17 11.1 0.1 4.8 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF4442 PF14539.6 AAG06407.1 - 0.19 11.9 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) AAA_28 PF13521.6 AAG06407.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.5 4 0 0 4 4 3 0 AAA domain DLIC PF05783.11 AAG06407.1 - 0.22 10.3 0.1 6.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) BEX PF04538.12 AAG06407.1 - 0.96 10.1 4.7 37 4.9 3.9 2.2 2 0 0 2 2 2 0 Brain expressed X-linked like family DUF87 PF01935.17 AAG06407.1 - 1.1 9.3 5.4 14 5.7 0.1 3.5 3 1 0 3 3 3 0 Helicase HerA, central domain SLT PF01464.20 AAG06408.1 - 3.9e-28 97.4 0.0 7.3e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_L PF14718.6 AAG06408.1 - 5.9e-17 61.6 3.9 5.9e-17 61.6 3.9 4.1 4 0 0 4 4 4 1 Soluble lytic murein transglycosylase L domain Cucumo_coat PF00760.18 AAG06408.1 - 0.0013 18.4 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Cucumovirus coat protein TPR_4 PF07721.14 AAG06408.1 - 1.4 9.8 9.6 0.87 10.4 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat LprI PF07007.12 AAG06409.1 - 7.9e-14 52.2 0.9 7.9e-14 52.2 0.9 1.5 1 1 1 2 2 2 1 Lysozyme inhibitor LprI DUF413 PF04219.12 AAG06409.1 - 0.0065 16.5 0.0 0.0085 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF MOSC_N PF03476.16 AAG06410.1 - 9.3e-35 119.1 0.0 1.3e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 AAG06410.1 - 2.6e-32 111.6 0.0 1.1e-31 109.6 0.0 1.8 2 0 0 2 2 2 1 MOSC domain DAGK_cat PF00781.24 AAG06411.1 - 3.5e-25 88.0 0.2 5.1e-25 87.5 0.2 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AAG06411.1 - 0.0083 15.4 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase FGGY_N PF00370.21 AAG06412.1 - 7.6e-45 153.4 0.0 1e-44 153.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AAG06412.1 - 2.5e-29 102.4 0.0 5.4e-29 101.3 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DAO PF01266.24 AAG06413.1 - 4e-49 168.1 3.7 5.7e-49 167.6 3.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 AAG06413.1 - 9.2e-14 51.4 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 AAG06413.1 - 6e-09 35.5 1.9 1.8e-07 30.6 1.9 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAG06413.1 - 0.00059 20.0 0.2 0.002 18.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAG06413.1 - 0.0012 18.2 0.1 0.0022 17.4 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAG06413.1 - 0.0096 15.2 0.0 0.066 12.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD-oxidase_C PF02913.19 AAG06414.1 - 5.8e-48 163.7 0.0 1.7e-46 158.9 0.0 2.0 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAG06414.1 - 2.5e-29 101.8 0.0 5.2e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ACP_syn_III PF08545.10 AAG06414.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Arabinose_bd PF12625.7 AAG06415.1 - 1.3e-51 175.3 0.9 1.3e-51 175.3 0.9 1.8 2 1 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG06415.1 - 1.2e-19 70.3 2.3 1.3e-19 70.2 0.4 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06415.1 - 1.7e-10 40.7 0.3 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r4_2 PF08281.12 AAG06415.1 - 7.8e-05 22.3 0.9 0.44 10.3 0.0 2.8 3 0 0 3 3 3 2 Sigma-70, region 4 SurA_N PF09312.11 AAG06415.1 - 0.00062 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 SurA N-terminal domain HTH_28 PF13518.6 AAG06415.1 - 0.0028 17.8 0.0 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG06415.1 - 0.015 15.1 0.0 1.1 9.2 0.0 2.7 1 1 0 2 2 2 0 Homeodomain-like domain Phage_integrase PF00589.22 AAG06415.1 - 0.046 13.5 0.2 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 Phage integrase family GGDEF_2 PF17853.1 AAG06415.1 - 0.34 11.2 2.2 2.4 8.4 0.1 2.7 2 1 0 2 2 2 0 GGDEF-like domain MoeA_N PF03453.17 AAG06416.1 - 3.6e-43 147.0 0.0 1.2e-42 145.4 0.0 1.8 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAG06416.1 - 1.2e-27 96.3 0.0 2.2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AAG06416.1 - 1.4e-15 57.2 0.3 3.6e-15 55.9 0.1 1.8 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) DUF1455 PF07306.11 AAG06416.1 - 0.047 13.7 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) MoCF_biosynth PF00994.24 AAG06417.1 - 4.3e-34 117.3 0.1 5.1e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain NTP_transf_3 PF12804.7 AAG06418.1 - 1.2e-31 110.2 0.8 1.5e-31 109.9 0.8 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF903 PF06004.12 AAG06419.1 - 1.7e-21 75.8 0.3 2e-21 75.6 0.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) FlbD PF06289.11 AAG06419.1 - 0.044 13.4 0.0 3.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins Cytochrome_CBB3 PF13442.6 AAG06420.1 - 0.0038 17.5 0.4 5.6 7.4 0.0 3.3 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III DUF1924 PF09086.11 AAG06420.1 - 0.0063 16.8 0.4 5.9 7.3 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1924) Cytochrom_C PF00034.21 AAG06420.1 - 0.013 16.6 2.9 0.82 10.8 0.9 3.8 4 1 0 4 4 4 0 Cytochrome c Cytochrome_C7 PF14522.6 AAG06420.1 - 0.075 13.0 0.3 8.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c CCP_MauG PF03150.14 AAG06420.1 - 0.17 12.5 0.0 12 6.5 0.0 2.3 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase DHOR PF06537.11 AAG06420.1 - 0.22 10.1 0.2 0.58 8.7 0.0 1.7 2 0 0 2 2 2 0 Di-haem oxidoreductase, putative peroxidase Paired_CXXCH_1 PF09699.10 AAG06420.1 - 0.31 10.8 3.0 14 5.5 0.8 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF836 PF05768.14 AAG06421.1 - 3.4e-16 59.4 0.0 3.9e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TetR_N PF00440.23 AAG06422.1 - 8.7e-16 57.4 0.2 2.5e-15 56.0 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AAG06422.1 - 0.013 15.7 2.9 0.013 15.7 2.9 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HrpB1_HrpK PF09613.10 AAG06422.1 - 0.039 13.6 1.1 0.046 13.3 0.2 1.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF3822 PF12864.7 AAG06422.1 - 0.047 12.9 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) HTH_Tnp_1_2 PF13022.6 AAG06422.1 - 0.063 13.4 0.1 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase GST_N PF02798.20 AAG06423.1 - 4.2e-12 46.2 0.0 6.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAG06423.1 - 1.3e-11 44.7 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG06423.1 - 9e-08 32.3 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG06423.1 - 2.1e-07 31.1 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAG06423.1 - 4.7e-07 29.7 0.5 1.7e-06 28.0 0.5 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG06423.1 - 1.6e-05 25.0 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAG06423.1 - 0.016 16.0 0.0 0.031 15.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain bMG1 PF17970.1 AAG06423.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG1 domain Putative_PNPOx PF01243.20 AAG06424.1 - 2.2e-25 88.7 0.0 8.3e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Lactamase_B PF00753.27 AAG06425.1 - 2.5e-27 96.2 1.5 3e-27 95.9 1.5 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG06425.1 - 6.2e-10 38.9 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAG06425.1 - 0.056 13.3 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain OprD PF03573.13 AAG06426.1 - 7e-166 552.1 6.4 7.9e-166 552.0 6.4 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Ammonium_transp PF00909.21 AAG06427.1 - 1.2e-85 287.6 34.1 1.6e-85 287.2 34.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF883 PF05957.13 AAG06428.1 - 3.5e-35 120.5 1.0 4.4e-35 120.2 1.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 AAG06428.1 - 4e-05 23.6 1.4 5e-05 23.3 1.4 1.1 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Syntaxin_2 PF14523.6 AAG06428.1 - 0.0092 16.3 0.5 0.016 15.6 0.5 1.4 1 1 0 1 1 1 1 Syntaxin-like protein HALZ PF02183.18 AAG06428.1 - 0.012 15.8 3.4 1.4 9.2 0.2 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Apolipoprotein PF01442.18 AAG06428.1 - 0.035 14.0 4.4 0.049 13.5 4.4 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CcmH PF03918.14 AAG06428.1 - 0.082 12.2 0.1 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 Cytochrome C biogenesis protein DUF1451 PF07295.11 AAG06428.1 - 0.21 11.6 2.4 0.25 11.4 2.4 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain YtxH PF12732.7 AAG06428.1 - 0.4 11.2 9.4 0.086 13.4 2.5 2.6 2 1 0 2 2 2 0 YtxH-like protein DinB_2 PF12867.7 AAG06428.1 - 0.42 11.1 2.4 16 6.0 0.4 2.1 1 1 1 2 2 2 0 DinB superfamily Phage_holin_3_6 PF07332.11 AAG06429.1 - 1.3e-19 70.3 2.6 1.7e-19 70.0 2.6 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 AAG06429.1 - 0.0069 16.1 8.8 0.01 15.5 8.2 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) SCAMP PF04144.13 AAG06429.1 - 0.02 15.2 0.2 0.027 14.8 0.2 1.1 1 0 0 1 1 1 0 SCAMP family CPP1-like PF11833.8 AAG06429.1 - 0.15 11.7 1.8 0.22 11.1 1.8 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HD PF01966.22 AAG06431.1 - 4.6e-09 36.5 0.0 1.5e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 HD domain HD_assoc PF13286.6 AAG06431.1 - 0.00031 21.2 0.0 0.00099 19.6 0.0 1.8 1 0 0 1 1 1 1 Phosphohydrolase-associated domain HD_6 PF18019.1 AAG06431.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 HD domain HATPase_c PF02518.26 AAG06432.1 - 3.6e-30 104.7 0.0 8.4e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAG06432.1 - 3.1e-24 85.3 0.0 6.5e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAG06432.1 - 7.4e-15 54.7 11.7 1.8e-14 53.5 0.2 4.9 3 1 1 4 4 4 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AAG06432.1 - 2.8e-13 49.9 7.5 2.8e-13 49.9 7.5 2.5 3 0 0 3 3 3 1 Hpt domain PAS_4 PF08448.10 AAG06432.1 - 7e-09 35.9 0.1 7e-09 35.9 0.1 2.5 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 AAG06432.1 - 8.9e-06 25.7 0.0 2.3e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AAG06432.1 - 0.00023 21.1 0.0 0.0044 17.0 0.0 2.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAG06432.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FleQ PF06490.11 AAG06432.1 - 0.16 12.4 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ Response_reg PF00072.24 AAG06433.1 - 3.7e-26 91.5 0.1 5.2e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG06433.1 - 3e-21 74.7 0.0 4.7e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG06433.1 - 0.003 17.2 0.1 0.0051 16.5 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG06433.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AAG06433.1 - 0.011 15.2 0.1 0.021 14.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Terminase_5 PF06056.12 AAG06433.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF469 PF04320.14 AAG06434.1 - 2.6e-36 124.5 0.1 2.9e-36 124.3 0.1 1.0 1 0 0 1 1 1 1 Protein with unknown function (DUF469) DUF4880 PF16220.5 AAG06434.1 - 0.032 14.1 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Peptidase_S13 PF02113.15 AAG06435.1 - 1.2e-86 291.2 0.0 1.5e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase2 PF13354.6 AAG06435.1 - 4.9e-06 26.3 0.1 0.0093 15.6 0.3 2.5 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 AAG06435.1 - 0.082 12.3 0.0 7.6 5.9 0.0 2.2 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase SdpA PF17418.2 AAG06435.1 - 0.088 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Sporulation delaying protein SdpA UPF0020 PF01170.18 AAG06436.1 - 5e-46 156.9 0.0 8.8e-43 146.3 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltrans_SAM PF10672.9 AAG06436.1 - 2.8e-19 69.3 0.0 4.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase THUMP PF02926.17 AAG06436.1 - 6.2e-12 45.8 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 THUMP domain Cons_hypoth95 PF03602.15 AAG06436.1 - 2.3e-09 37.2 0.0 3.7e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 AAG06436.1 - 3.2e-06 27.7 0.0 3.4e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAG06436.1 - 1.6e-05 24.5 0.0 0.0041 16.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_15 PF09445.10 AAG06436.1 - 3.8e-05 23.3 0.0 0.00063 19.4 0.0 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 AAG06436.1 - 0.00021 22.3 0.0 0.0029 18.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG06436.1 - 0.0036 17.9 0.0 0.02 15.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain RMF PF04957.12 AAG06437.1 - 5.5e-27 93.7 1.3 6.7e-27 93.5 1.3 1.1 1 0 0 1 1 1 1 Ribosome modulation factor DHO_dh PF01180.21 AAG06438.1 - 1.8e-86 290.0 0.0 2.7e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 AAG06438.1 - 6.9e-05 22.4 7.2 0.00019 21.0 7.1 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase DUF3372 PF11852.8 AAG06438.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3372) IMPDH PF00478.25 AAG06438.1 - 0.14 11.1 0.8 0.34 9.8 0.2 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AAG06438.1 - 0.28 10.1 8.7 0.086 11.8 5.7 1.9 2 1 0 2 2 2 0 FMN-dependent dehydrogenase DUF2835 PF11197.8 AAG06439.1 - 1.7e-26 91.9 0.0 2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2835) Abhydrolase_1 PF00561.20 AAG06441.1 - 1.4e-24 87.1 0.3 1.3e-23 83.9 0.3 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06441.1 - 1.6e-21 76.7 0.1 5.7e-21 74.9 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAG06441.1 - 2.5e-21 77.3 1.3 3.4e-21 76.9 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 AAG06441.1 - 5.3e-06 25.7 0.0 7.4e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 AAG06441.1 - 1.4e-05 23.9 0.0 5.4e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Ndr family DUF915 PF06028.11 AAG06441.1 - 0.0027 17.1 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 AAG06441.1 - 0.0036 17.0 0.1 0.0069 16.1 0.1 1.5 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 AAG06441.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Peptidase_S37 PF05576.11 AAG06441.1 - 0.0096 14.6 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 1 PS-10 peptidase S37 PGAP1 PF07819.13 AAG06441.1 - 0.015 15.0 0.0 0.03 14.1 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.7 AAG06441.1 - 0.019 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.20 AAG06441.1 - 0.019 15.1 0.1 0.037 14.1 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 AAG06441.1 - 0.024 14.5 0.1 0.034 14.0 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 AAG06441.1 - 0.034 14.0 0.1 0.14 12.0 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase DUF676 PF05057.14 AAG06441.1 - 0.055 13.0 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 AAG06441.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Acyl_transf_1 PF00698.21 AAG06441.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain Lipase_3 PF01764.25 AAG06441.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 AAG06441.1 - 0.17 11.6 0.0 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 AAG06441.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 2) Peptidase_M14 PF00246.24 AAG06442.1 - 2e-18 67.2 0.0 2.1e-17 63.9 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase HTH_31 PF13560.6 AAG06443.1 - 0.0015 18.9 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG06443.1 - 0.027 14.5 0.2 0.056 13.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 AAG06444.1 - 3.3e-08 33.7 0.6 9.7e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG06444.1 - 4.1e-06 26.7 0.0 8.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAG06444.1 - 0.00081 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 AAG06444.1 - 0.0014 18.4 0.4 0.0025 17.6 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 AAG06445.1 - 0.033 14.4 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PelG PF16933.5 AAG06446.1 - 9.5e-158 525.8 41.7 1.1e-157 525.6 41.7 1.0 1 0 0 1 1 1 1 Putative exopolysaccharide Exporter (EPS-E) DUF2070 PF09843.9 AAG06446.1 - 5 5.3 44.4 0.033 12.5 25.4 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3492 PF11997.8 AAG06447.1 - 4.9e-92 308.5 0.0 6.5e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Glycos_transf_1 PF00534.20 AAG06447.1 - 2.2e-22 79.4 0.0 3.6e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG06447.1 - 4.5e-22 78.9 0.1 7.2e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG06447.1 - 3e-07 30.6 0.1 1.1e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAG06447.1 - 5.1e-07 30.0 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAG06447.1 - 0.00078 19.9 2.6 0.00098 19.6 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain HEAT_2 PF13646.6 AAG06448.1 - 0.00012 22.4 0.3 0.00029 21.1 0.3 1.6 1 0 0 1 1 1 1 HEAT repeats TPR_16 PF13432.6 AAG06448.1 - 0.00034 21.2 4.3 0.00034 21.2 4.3 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAG06448.1 - 0.032 14.7 3.6 0.032 14.7 3.6 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 AAG06448.1 - 0.13 12.6 0.1 12 6.4 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat TPR_2 PF07719.17 AAG06448.1 - 0.87 9.9 5.7 3.1 8.2 1.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PelD_GGDEF PF16963.5 AAG06449.1 - 1.9e-35 121.4 0.6 3.9e-35 120.4 0.6 1.5 1 0 0 1 1 1 1 PelD GGDEF domain GAF_3 PF13492.6 AAG06449.1 - 2.2e-07 31.3 0.3 4.8e-07 30.2 0.3 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAG06449.1 - 7.1e-07 29.6 1.1 1.4e-06 28.6 1.1 1.5 1 0 0 1 1 1 1 GAF domain PAS_4 PF08448.10 AAG06449.1 - 0.00037 20.7 1.0 0.26 11.5 0.1 2.7 2 0 0 2 2 2 2 PAS fold GAF PF01590.26 AAG06449.1 - 0.0017 19.0 3.1 0.0019 18.8 0.3 2.3 2 1 1 3 3 3 1 GAF domain DUF4118 PF13493.6 AAG06449.1 - 0.29 10.9 9.6 0.36 10.7 3.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) TPR_15 PF13429.6 AAG06451.1 - 9.2e-92 307.2 25.9 9.2e-92 307.2 25.9 4.3 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAG06451.1 - 1.4e-05 25.5 0.2 1.4e-05 25.5 0.2 10.2 8 3 3 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 AAG06451.1 - 0.00055 20.5 4.6 0.0079 16.9 0.2 16.1 8 5 10 18 18 18 5 Tetratricopeptide repeat TPR_2 PF07719.17 AAG06451.1 - 0.0083 16.2 24.7 0.15 12.3 0.9 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAG06451.1 - 0.034 14.4 0.5 24 5.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAG06451.1 - 0.13 12.6 3.7 7.8 6.8 0.1 4.4 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AAG06451.1 - 0.15 12.0 2.7 13 5.8 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_114 PF03537.13 AAG06452.1 - 1.4e-16 60.5 0.0 2.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_deac_1 PF01522.21 AAG06452.1 - 0.024 14.5 0.0 0.063 13.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide deacetylase FUSC_2 PF13515.6 AAG06453.1 - 8.5e-09 35.6 10.9 8.5e-09 35.6 10.9 3.2 1 1 0 2 2 2 1 Fusaric acid resistance protein-like Isochorismatase PF00857.20 AAG06454.1 - 1.3e-29 103.6 0.0 1.4e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family MarR PF01047.22 AAG06455.1 - 1.3e-10 41.0 0.1 2.4e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAG06455.1 - 7.7e-09 35.9 0.3 1.5e-08 35.0 0.1 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AAG06455.1 - 1.2e-08 34.7 0.8 1.2e-08 34.7 0.8 2.1 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAG06455.1 - 0.0043 17.1 2.9 0.0043 17.1 2.9 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain HxlR PF01638.17 AAG06455.1 - 0.0043 16.9 0.2 0.0072 16.2 0.0 1.6 2 0 0 2 2 2 1 HxlR-like helix-turn-helix DUF3376 PF11856.8 AAG06455.1 - 0.015 14.4 1.9 0.016 14.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) HTH_34 PF13601.6 AAG06455.1 - 0.023 14.9 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAG06455.1 - 0.025 14.4 0.6 0.025 14.4 0.6 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AAG06455.1 - 0.067 12.8 1.2 0.7 9.5 0.1 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Bac_GDH PF05088.12 AAG06456.1 - 0 2210.8 0.0 0 2210.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 AAG06456.1 - 0.00021 21.1 1.0 0.0019 18.0 0.1 2.3 2 1 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HTH_31 PF13560.6 AAG06456.1 - 0.035 14.4 0.3 13 6.3 0.0 4.2 3 0 0 3 3 3 0 Helix-turn-helix domain PAS_3 PF08447.12 AAG06456.1 - 0.12 12.7 0.0 0.48 10.7 0.0 2.1 1 0 0 1 1 1 0 PAS fold AAA_3 PF07726.11 AAG06458.1 - 4.6e-64 214.2 0.1 8.6e-64 213.3 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAG06458.1 - 6.4e-20 70.8 0.2 1.5e-19 69.6 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAG06458.1 - 4.4e-12 46.2 0.0 9.6e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAG06458.1 - 2.7e-05 23.4 0.0 4.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AAG06458.1 - 0.003 17.3 0.0 0.0088 15.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AAG06458.1 - 0.0038 16.6 0.2 0.77 9.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAG06458.1 - 0.0082 15.9 0.1 0.18 11.5 0.1 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AAG06458.1 - 0.0092 16.4 0.0 0.051 14.0 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF58 PF01882.18 AAG06459.1 - 8.3e-21 74.1 0.0 2.1e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF58 DUF4381 PF14316.6 AAG06460.1 - 5.3e-44 150.0 9.2 6.1e-44 149.8 9.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) PhoR PF11808.8 AAG06460.1 - 0.0016 18.8 0.4 0.0036 17.7 0.4 1.5 1 0 0 1 1 1 1 Phosphate regulon sensor protein PhoR VWA PF00092.28 AAG06461.1 - 3.5e-32 112.1 0.0 4.4e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AAG06461.1 - 2.1e-18 66.9 0.0 4.6e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 AAG06461.1 - 1.7e-08 34.0 1.0 0.00057 19.2 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_3 PF13768.6 AAG06461.1 - 0.014 15.3 0.1 0.28 11.1 0.1 2.6 2 1 0 2 2 2 0 von Willebrand factor type A domain VWA_CoxE PF05762.14 AAG06461.1 - 0.066 12.6 0.3 4.6 6.6 0.1 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VWA_2 PF13519.6 AAG06462.1 - 1.1e-10 42.1 0.2 2.8e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain TPR_1 PF00515.28 AAG06462.1 - 6.8e-09 35.2 5.3 1.7e-08 33.9 0.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAG06462.1 - 9e-08 31.7 15.1 6.6e-07 29.0 1.3 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAG06462.1 - 2.6e-05 23.8 6.0 5.6e-05 22.8 1.4 3.1 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 AAG06462.1 - 0.0001 22.2 1.6 0.00042 20.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAG06462.1 - 0.00023 21.8 9.6 0.00023 21.8 9.6 5.0 4 1 1 5 5 4 1 Tetratricopeptide repeat VWA PF00092.28 AAG06462.1 - 0.00042 20.6 0.0 0.00071 19.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TPR_14 PF13428.6 AAG06462.1 - 0.00083 20.0 3.1 0.00083 20.0 3.1 6.5 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 AAG06462.1 - 0.0071 16.5 3.8 0.0071 16.5 3.8 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAG06462.1 - 0.0088 16.0 0.5 0.0088 16.0 0.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAG06462.1 - 0.019 15.6 0.4 0.019 15.6 0.4 4.5 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAG06462.1 - 0.022 14.7 1.2 0.022 14.7 1.2 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAG06462.1 - 0.084 13.5 0.9 0.084 13.5 0.9 6.2 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAG06462.1 - 0.13 12.7 6.3 7.1 7.2 0.4 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Bac_rhodopsin PF01036.18 AAG06462.1 - 0.23 11.0 1.0 0.41 10.2 1.0 1.3 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein BatD PF13584.6 AAG06463.1 - 1.1e-108 364.2 0.0 1.4e-108 363.8 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance Chlorophyllase2 PF12740.7 AAG06464.1 - 1.1e-13 50.6 0.0 1.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 AAG06464.1 - 1.9e-07 31.2 0.1 2.8e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 AAG06464.1 - 1.2e-06 27.8 0.0 1.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 AAG06464.1 - 0.16 11.2 0.3 0.78 8.9 0.1 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Response_reg PF00072.24 AAG06465.1 - 2.7e-26 91.9 0.0 3.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG06465.1 - 1.9e-18 66.3 0.0 3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HisKA PF00512.25 AAG06466.1 - 6.5e-12 45.3 0.2 2.5e-11 43.5 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAG06466.1 - 0.0017 18.8 0.1 0.094 13.2 0.1 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAG06466.1 - 0.011 15.6 0.0 0.092 12.7 0.0 2.4 2 1 0 2 2 2 0 GHKL domain Lipoprotein_15 PF03640.15 AAG06466.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 Secreted repeat of unknown function MMPL PF03176.15 AAG06467.1 - 1.1e-32 113.4 21.1 2.2e-27 95.9 7.1 3.1 3 0 0 3 3 3 3 MMPL family Patched PF02460.18 AAG06467.1 - 0.00011 20.5 0.2 0.00011 20.5 0.2 3.2 3 0 0 3 3 3 1 Patched family ACR_tran PF00873.19 AAG06467.1 - 0.00048 17.9 9.5 0.00048 17.9 9.5 2.7 3 0 0 3 3 3 1 AcrB/AcrD/AcrF family PSII_BNR PF14870.6 AAG06468.1 - 7.6e-27 94.3 6.6 5.7e-16 58.6 0.9 4.2 1 1 3 4 4 4 4 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 AAG06468.1 - 1e-12 47.7 0.0 0.0021 16.9 0.0 3.6 1 1 0 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 AAG06468.1 - 1.7e-09 36.2 16.7 0.53 10.5 0.3 6.8 6 0 0 6 6 6 5 BNR/Asp-box repeat BNR_6 PF15899.5 AAG06468.1 - 2.9e-09 36.1 2.2 0.026 14.6 0.1 4.3 4 0 0 4 4 4 2 BNR-Asp box repeat BNR_2 PF13088.6 AAG06468.1 - 2e-05 24.1 0.7 0.19 11.0 0.2 4.5 1 1 1 2 2 2 2 BNR repeat-like domain DUF4185 PF13810.6 AAG06468.1 - 0.00032 20.0 3.2 4.1 6.5 0.0 4.8 2 2 4 6 6 6 2 Domain of unknown function (DUF4185) DUF5122 PF17164.4 AAG06468.1 - 2.3 8.6 4.8 1.2 9.4 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller DUF1329 PF07044.11 AAG06469.1 - 2.6e-160 533.6 2.7 3.1e-160 533.4 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) LolA_like PF17131.4 AAG06469.1 - 2.3e-07 30.7 0.0 1.7e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 Outer membrane lipoprotein-sorting protein DUF1302 PF06980.11 AAG06470.1 - 1.2e-185 618.5 19.2 1.4e-185 618.3 19.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) DUF3458_C PF17432.2 AAG06471.1 - 3.4e-123 411.1 3.1 6.3e-123 410.2 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 AAG06471.1 - 1.2e-54 185.1 0.3 1.9e-54 184.6 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 AAG06471.1 - 5e-31 107.0 0.0 1.1e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 AAG06471.1 - 1.1e-14 55.1 0.0 1.8e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 AAG06471.1 - 0.0089 16.4 0.2 0.05 14.0 0.2 2.2 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Reprolysin_3 PF13582.6 AAG06471.1 - 0.15 12.6 0.1 0.31 11.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF2268 PF10026.9 AAG06471.1 - 0.16 11.5 0.0 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) DUF2797 PF10977.8 AAG06472.1 - 2.5e-98 328.6 0.0 2.9e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2797) DUF1315 PF07023.12 AAG06473.1 - 2.3e-28 98.1 0.0 2.6e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1315) NRho PF16733.5 AAG06474.1 - 1.2e-33 114.9 0.3 2.5e-33 113.9 0.3 1.5 1 0 0 1 1 1 1 Rhomboid N-terminal domain Rhomboid PF01694.22 AAG06474.1 - 7.8e-30 103.9 17.8 7.8e-30 103.9 17.8 1.4 2 0 0 2 2 2 1 Rhomboid family Metallophos PF00149.28 AAG06475.1 - 4.2e-10 40.5 0.0 6.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_kinase PF01513.21 AAG06476.1 - 3.9e-69 233.1 0.2 1.2e-68 231.4 0.2 1.7 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AAG06476.1 - 0.00024 20.7 0.1 0.0004 20.0 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1853 PF08907.11 AAG06477.1 - 1.2e-94 317.2 9.1 1.4e-94 317.0 9.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1853) NAD_binding_9 PF13454.6 AAG06477.1 - 0.011 15.8 0.3 0.025 14.6 0.3 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Peptidase_M55 PF04951.13 AAG06479.1 - 0.15 11.4 0.0 0.63 9.4 0.0 2.0 2 0 0 2 2 2 0 D-aminopeptidase Exonuc_VII_L PF02601.15 AAG06479.1 - 0.79 9.2 18.0 1.3 8.5 18.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 AAG06479.1 - 4.7 7.1 11.9 6.3 6.7 11.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Oxidored_FMN PF00724.20 AAG06480.1 - 2.7e-89 299.8 0.0 3.4e-89 299.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AAG06480.1 - 1.1e-22 80.6 2.5 2e-22 79.8 2.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG06480.1 - 8.4e-09 35.5 0.1 2.6e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAG06480.1 - 2.1e-07 31.4 5.9 0.00037 21.0 1.0 4.2 4 1 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG06480.1 - 3.4e-07 30.0 0.1 5.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG06480.1 - 8.1e-07 28.1 1.4 8.1e-07 28.1 1.4 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 AAG06480.1 - 2.8e-06 26.8 0.6 0.058 12.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG06480.1 - 3.9e-05 22.9 4.1 8.5e-05 21.8 3.5 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 AAG06480.1 - 7.8e-05 22.6 0.4 0.01 15.7 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAG06480.1 - 0.0003 20.1 0.0 0.0003 20.1 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AAG06480.1 - 0.00031 19.9 0.2 0.00031 19.9 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 AAG06480.1 - 0.0012 18.5 9.2 0.01 15.5 1.6 4.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 AAG06480.1 - 0.0025 17.8 0.4 0.1 12.6 0.0 2.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 AAG06480.1 - 0.005 16.1 2.0 0.019 14.2 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 AAG06480.1 - 0.0065 15.8 1.4 0.23 10.7 0.5 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 AAG06480.1 - 0.0074 15.5 1.3 0.0093 15.2 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 AAG06480.1 - 0.058 13.4 1.7 0.91 9.5 0.3 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 AAG06480.1 - 0.089 12.4 1.4 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 AAG06480.1 - 0.12 11.8 0.6 6.7 6.0 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 AAG06480.1 - 0.14 10.5 0.0 0.27 9.6 0.0 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like CN_hydrolase PF00795.22 AAG06481.1 - 2e-10 40.4 0.0 1.4e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Cupin_1 PF00190.22 AAG06481.1 - 0.16 11.6 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Cupin Arabinose_bd PF12625.7 AAG06482.1 - 1.1e-47 162.6 3.7 1.8e-47 161.8 3.7 1.4 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG06482.1 - 1.7e-14 53.8 1.6 3.9e-14 52.7 0.8 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06482.1 - 4e-08 33.2 0.0 8.6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family SurA_N PF09312.11 AAG06482.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain T2SSM PF04612.12 AAG06483.1 - 8e-45 152.8 11.5 9.4e-45 152.5 11.5 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M T2SSL PF05134.13 AAG06484.1 - 4.5e-57 193.1 1.1 5.8e-57 192.7 1.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein L GspL_C PF12693.7 AAG06484.1 - 5.4e-46 156.3 2.0 9.5e-46 155.5 2.0 1.4 1 0 0 1 1 1 1 GspL periplasmic domain T2SSK PF03934.13 AAG06485.1 - 2.7e-87 292.7 0.4 3.2e-87 292.5 0.4 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_3 PF12836.7 AAG06485.1 - 2.4e-07 30.9 0.0 4.9e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SSJ PF11612.8 AAG06486.1 - 3.5e-45 153.7 6.0 4.9e-45 153.2 6.0 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J N_methyl PF07963.12 AAG06486.1 - 3.9e-10 38.8 2.1 5.8e-10 38.3 2.1 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DUF3325 PF11804.8 AAG06486.1 - 0.055 13.6 0.3 0.12 12.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) T2SSI PF02501.17 AAG06487.1 - 8.8e-30 102.7 1.6 1.4e-29 102.1 1.6 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein I N_methyl PF07963.12 AAG06487.1 - 4.1e-10 38.8 3.1 6.4e-10 38.2 3.1 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif PulG PF11773.8 AAG06487.1 - 0.069 13.0 0.7 0.097 12.5 0.7 1.3 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin GspH PF12019.8 AAG06488.1 - 3.5e-10 40.3 0.0 4.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AAG06488.1 - 1.1e-09 37.4 5.7 2.2e-09 36.5 5.7 1.6 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DUF294 PF03445.13 AAG06488.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 T2SSG PF08334.11 AAG06489.1 - 2.1e-44 150.0 0.8 2.5e-44 149.8 0.8 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AAG06489.1 - 4.4e-10 38.7 2.8 6.7e-10 38.1 2.8 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSF PF00482.23 AAG06490.1 - 1.8e-56 189.5 17.9 2.2e-28 98.7 3.6 2.5 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F DUF2062 PF09835.9 AAG06490.1 - 0.33 10.8 5.0 7.3 6.4 0.3 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) T2SSE PF00437.20 AAG06491.1 - 1.1e-92 310.0 5.1 1.4e-92 309.6 5.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AAG06491.1 - 0.00032 21.1 1.2 0.00063 20.2 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAG06491.1 - 0.00046 20.5 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG06491.1 - 0.0021 17.8 0.1 0.0049 16.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG06491.1 - 0.0023 18.5 0.0 0.0039 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG06491.1 - 0.0027 17.4 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AAG06491.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAG06491.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 AAG06491.1 - 0.014 15.7 0.4 0.04 14.3 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 AAG06491.1 - 0.038 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE_N PF05157.15 AAG06491.1 - 0.048 13.9 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain ATPase_2 PF01637.18 AAG06491.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AAG06491.1 - 0.075 12.6 0.1 0.84 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAG06491.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.29 AAG06491.1 - 0.12 12.2 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 AAG06491.1 - 0.12 11.6 0.0 0.45 9.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 AAG06491.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 AAG06491.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 AAG06491.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 AAG06491.1 - 0.18 11.9 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 AAG06491.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 AAG06491.1 - 1 9.3 3.5 4 7.3 1.5 2.3 1 1 1 2 2 2 0 NTPase T2SSC PF11356.8 AAG06492.1 - 4.4e-22 78.5 0.0 6.9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Type II secretion system protein C Yop-YscD_ppl PF16693.5 AAG06492.1 - 0.057 12.9 0.1 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Inner membrane component of T3SS, periplasmic domain Secretin PF00263.21 AAG06493.1 - 2.9e-54 183.3 2.8 1.4e-53 181.0 3.6 1.8 2 0 0 2 2 2 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAG06493.1 - 1.5e-41 140.7 10.6 5.2e-16 58.8 0.4 3.9 3 0 0 3 3 3 3 Bacterial type II/III secretion system short domain adh_short_C2 PF13561.6 AAG06494.1 - 9.1e-68 228.3 0.3 1e-67 228.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06494.1 - 2.1e-47 161.2 0.0 2.6e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG06494.1 - 2.3e-09 37.4 0.2 3.3e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG06494.1 - 0.064 12.7 0.3 0.16 11.4 0.1 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Cys_Met_Meta_PP PF01053.20 AAG06495.1 - 2.3e-144 480.6 0.0 2.6e-144 480.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AAG06495.1 - 5e-13 49.0 0.0 7.3e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAG06495.1 - 1.1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AAG06495.1 - 1.5e-07 31.1 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAG06495.1 - 7.7e-05 22.1 0.0 0.019 14.3 0.0 2.3 2 0 0 2 2 2 2 Beta-eliminating lyase GDC-P PF02347.16 AAG06495.1 - 0.0016 17.3 0.0 0.0024 16.8 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 AAG06495.1 - 0.0033 16.0 0.0 0.0053 15.3 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GATase_6 PF13522.6 AAG06496.1 - 2.8e-15 56.7 0.0 5.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AAG06496.1 - 2e-11 43.9 0.0 4.8e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AAG06496.1 - 2.7e-09 36.7 0.0 5.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AAG06496.1 - 4.7e-05 22.4 0.0 7.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 AAG06496.1 - 0.071 12.6 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase Colicin_V PF02674.16 AAG06497.1 - 4.3e-35 120.8 14.7 5.5e-35 120.5 14.7 1.1 1 0 0 1 1 1 1 Colicin V production protein SPC12 PF06645.13 AAG06497.1 - 0.043 13.9 1.4 0.043 13.9 1.4 2.7 1 1 2 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF373 PF04123.13 AAG06497.1 - 0.14 11.6 2.3 0.16 11.3 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MerC PF03203.14 AAG06497.1 - 1.4 9.3 12.4 0.8 10.2 7.9 2.2 2 0 0 2 2 2 0 MerC mercury resistance protein SPOR PF05036.13 AAG06498.1 - 9.6e-18 64.4 0.4 1.5e-17 63.8 0.4 1.3 1 0 0 1 1 1 1 Sporulation related domain Mur_ligase_M PF08245.12 AAG06499.1 - 1.9e-11 44.4 0.0 2.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAG06499.1 - 0.00055 20.1 0.1 0.006 16.8 0.0 2.5 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain YjeF_N PF03853.15 AAG06499.1 - 0.064 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Carboxyl_trans PF01039.22 AAG06500.1 - 2.2e-17 62.9 0.0 3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 AAG06500.1 - 8.4e-12 44.9 4.3 1.6e-11 44.0 4.3 1.5 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain Ogr_Delta PF04606.12 AAG06500.1 - 0.035 14.1 0.7 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Auto_anti-p27 PF06677.12 AAG06500.1 - 0.19 11.9 1.2 0.45 10.7 1.2 1.7 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 AAG06500.1 - 0.7 9.4 3.2 13 5.4 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain PRAI PF00697.22 AAG06501.1 - 7e-45 153.2 0.0 7.9e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase PseudoU_synth_1 PF01416.20 AAG06502.1 - 1.1e-39 135.2 0.1 5.2e-31 107.3 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase TPR_19 PF14559.6 AAG06503.1 - 1.1e-06 29.0 7.3 0.00037 20.9 1.5 4.8 5 1 1 6 6 3 2 Tetratricopeptide repeat LysM PF01476.20 AAG06503.1 - 0.00059 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 LysM domain TPR_14 PF13428.6 AAG06503.1 - 0.0015 19.1 6.8 0.046 14.6 1.6 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 AAG06503.1 - 0.0019 18.7 2.9 0.0019 18.7 2.9 2.2 2 0 0 2 2 1 1 Bacterial transcriptional activator domain MCC-bdg_PDZ PF10506.9 AAG06503.1 - 0.0042 17.1 2.4 0.24 11.4 1.6 2.7 2 0 0 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Alkyl_sulf_dimr PF14863.6 AAG06503.1 - 0.0054 17.2 0.5 1.3 9.5 0.1 2.6 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation Sec2p PF06428.11 AAG06503.1 - 0.0073 16.2 4.5 0.41 10.6 4.8 2.6 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Atg14 PF10186.9 AAG06503.1 - 0.0099 15.0 0.8 0.017 14.2 0.8 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 AAG06503.1 - 0.021 15.0 1.1 0.071 13.3 1.1 1.9 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Cytochrom_B562 PF07361.11 AAG06503.1 - 0.027 15.1 15.9 0.17 12.6 0.7 4.0 4 1 1 5 5 3 0 Cytochrome b562 TPR_4 PF07721.14 AAG06503.1 - 0.051 14.2 0.1 0.051 14.2 0.1 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAG06503.1 - 0.052 13.9 1.7 1.5 9.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF812 PF05667.11 AAG06503.1 - 0.067 12.1 3.3 0.055 12.4 1.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) HAUS-augmin3 PF14932.6 AAG06503.1 - 0.08 12.5 2.7 0.16 11.5 2.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TPR_11 PF13414.6 AAG06503.1 - 0.14 11.9 1.5 0.16 11.7 0.4 1.8 2 0 0 2 2 1 0 TPR repeat MRP-S27 PF10037.9 AAG06503.1 - 0.17 10.7 2.0 0.38 9.5 0.7 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_10 PF13374.6 AAG06503.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAG06503.1 - 0.19 12.0 0.6 3.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc7 PF08317.11 AAG06503.1 - 0.19 10.6 3.1 0.26 10.1 1.9 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 AAG06503.1 - 0.24 11.6 18.4 0.066 13.4 11.2 3.4 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) TPR_6 PF13174.6 AAG06503.1 - 0.33 11.7 10.4 1 10.1 0.0 4.8 4 1 1 5 5 4 0 Tetratricopeptide repeat FAM76 PF16046.5 AAG06503.1 - 0.4 10.0 1.7 0.63 9.3 1.7 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1664 PF07889.12 AAG06503.1 - 0.4 10.7 2.0 2 8.5 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_9 PF13371.6 AAG06503.1 - 0.51 10.5 6.8 2.8 8.1 1.9 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 AAG06503.1 - 0.51 10.6 5.8 8 6.9 0.4 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 AAG06503.1 - 0.52 10.8 6.1 1.8 9.0 4.0 2.5 2 0 0 2 2 2 0 Snapin/Pallidin SlyX PF04102.12 AAG06503.1 - 0.59 10.8 5.1 9.4 6.9 3.2 3.4 2 0 0 2 2 2 0 SlyX EAP30 PF04157.16 AAG06503.1 - 0.67 9.2 5.2 7.8 5.7 2.0 2.5 2 0 0 2 2 2 0 EAP30/Vps36 family Spc24 PF08286.11 AAG06503.1 - 3.5 7.9 4.8 16 5.8 2.8 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4763 PF15960.5 AAG06503.1 - 4.3 6.6 6.8 1.1 8.5 3.1 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4763) TPR_7 PF13176.6 AAG06503.1 - 4.9 7.4 5.6 10 6.4 0.2 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat Semialdhyde_dhC PF02774.18 AAG06504.1 - 3.8e-33 115.1 0.0 5.1e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AAG06504.1 - 5.2e-24 85.0 0.2 1.1e-23 83.9 0.2 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PmbA_TldD PF01523.16 AAG06504.1 - 0.18 11.7 0.1 0.37 10.6 0.0 1.5 2 0 0 2 2 2 0 Putative modulator of DNA gyrase Semialdhyde_dhC PF02774.18 AAG06505.1 - 3.6e-63 213.0 0.0 4.7e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AAG06505.1 - 3.3e-25 88.9 0.0 9.5e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Iso_dh PF00180.20 AAG06506.1 - 9.3e-140 465.7 0.0 1.1e-139 465.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_11 PF08241.12 AAG06507.1 - 3.8e-19 69.1 0.0 6.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG06507.1 - 4e-16 59.5 0.0 7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAG06507.1 - 1e-12 47.9 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 AAG06507.1 - 7.7e-12 45.3 0.0 8.5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG06507.1 - 8.2e-11 42.0 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG06507.1 - 4.6e-08 33.7 0.0 6.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 AAG06507.1 - 0.0018 16.9 0.0 0.0023 16.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Aconitase_C PF00694.19 AAG06508.1 - 5e-39 133.6 0.0 6.6e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.20 AAG06509.1 - 3.2e-161 537.4 0.1 3.7e-161 537.2 0.1 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) LysR_substrate PF03466.20 AAG06510.1 - 1.1e-45 155.6 6.1 1.7e-45 155.0 6.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06510.1 - 2.2e-23 82.0 0.9 2.2e-23 82.0 0.9 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 AAG06510.1 - 0.0011 18.7 0.1 0.0067 16.2 0.0 2.2 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAG06510.1 - 0.017 15.0 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 MarR family Glyco_trans_1_3 PF13528.6 AAG06510.1 - 0.066 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 HTH_24 PF13412.6 AAG06510.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ribonuc_L-PSP PF01042.21 AAG06511.1 - 7.4e-28 97.0 0.0 9e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP LysR_substrate PF03466.20 AAG06512.1 - 3.6e-41 140.8 7.1 4.8e-41 140.4 7.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06512.1 - 5e-21 74.4 0.3 1.3e-20 73.1 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG06512.1 - 0.00096 19.0 0.0 0.0045 16.8 0.0 2.2 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAG06512.1 - 0.0015 18.3 0.2 0.018 14.9 0.0 2.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AAG06512.1 - 0.043 13.4 0.1 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2894 PF11445.8 AAG06512.1 - 0.044 14.3 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) YdaS_antitoxin PF15943.5 AAG06512.1 - 0.046 13.6 0.0 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_28 PF13518.6 AAG06512.1 - 0.075 13.2 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 AAG06512.1 - 0.11 12.6 0.0 2.4 8.3 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix MarR PF01047.22 AAG06512.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.9 1 0 0 1 1 1 0 MarR family Lipase_GDSL_2 PF13472.6 AAG06513.1 - 8.9e-27 94.6 0.9 1.8e-26 93.6 0.9 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AAG06513.1 - 8.4e-10 38.9 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 AAG06513.1 - 0.0074 16.4 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family HSP20 PF00011.21 AAG06514.1 - 6.4e-17 61.6 0.0 8.4e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAG06514.1 - 0.00086 18.8 0.1 0.0027 17.2 0.1 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Acetyltransf_1 PF00583.25 AAG06515.1 - 1.8e-08 34.6 0.1 4.5e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG06515.1 - 3.5e-08 33.8 0.0 1.4e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG06515.1 - 1.4e-07 31.5 0.0 4.4e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG06515.1 - 2.5e-05 24.1 0.0 0.00048 20.1 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Glyoxalase PF00903.25 AAG06515.1 - 5.9e-05 23.3 0.0 0.00016 21.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_9 PF13527.7 AAG06515.1 - 0.0045 17.1 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase_2 PF12681.7 AAG06515.1 - 0.0045 16.9 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Acetyltransf_CG PF14542.6 AAG06515.1 - 0.044 13.9 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 AAG06515.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase adh_short_C2 PF13561.6 AAG06516.1 - 3.9e-63 213.1 2.9 4.4e-63 213.0 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06516.1 - 4.1e-52 176.5 0.5 5e-52 176.2 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG06516.1 - 2.3e-16 60.2 0.8 3.2e-16 59.8 0.8 1.2 1 0 0 1 1 1 1 KR domain SPOR PF05036.13 AAG06516.1 - 0.027 14.9 0.2 0.12 12.7 0.2 2.1 2 0 0 2 2 2 0 Sporulation related domain Epimerase PF01370.21 AAG06516.1 - 0.035 13.6 1.3 0.079 12.4 0.4 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAG06516.1 - 0.12 12.2 3.1 0.45 10.4 3.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding CMD PF02627.20 AAG06516.1 - 0.96 9.5 5.7 18 5.5 0.0 2.9 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family Dus PF01207.17 AAG06517.1 - 1.6e-64 217.9 0.0 2.1e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Acyl-ACP_TE PF01643.17 AAG06518.1 - 6.2e-13 48.6 0.0 2.7e-07 30.1 0.0 2.0 1 1 1 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 AAG06518.1 - 2.3e-12 47.5 0.0 2.8e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAG06518.1 - 2.1e-10 40.8 0.0 3.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Aldolase PF01081.19 AAG06519.1 - 2.1e-68 229.6 0.0 2.4e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase DUF4129 PF13559.6 AAG06519.1 - 0.015 15.5 1.4 0.077 13.3 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4129) KDGP_aldolase PF07071.11 AAG06519.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 KDGP aldolase Hydrolase_4 PF12146.8 AAG06520.1 - 4.5e-15 55.6 2.4 8.9e-12 44.8 1.3 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG06520.1 - 5.2e-12 46.0 0.2 1.2e-07 31.6 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG06520.1 - 3.7e-11 44.0 22.2 1e-10 42.6 17.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AAG06520.1 - 3.2e-05 23.9 0.1 0.00029 20.8 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase Acyl_transf_1 PF00698.21 AAG06520.1 - 0.001 18.6 0.2 0.0014 18.2 0.2 1.2 1 0 0 1 1 1 1 Acyl transferase domain Lipase_3 PF01764.25 AAG06520.1 - 0.0012 18.7 0.2 0.0018 18.1 0.2 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.9 AAG06520.1 - 0.0037 16.8 1.6 0.023 14.2 1.7 2.2 2 1 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 AAG06520.1 - 0.014 15.0 0.3 0.027 14.1 0.3 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 AAG06520.1 - 0.018 15.2 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_5 PF12695.7 AAG06520.1 - 0.028 14.2 0.4 0.063 13.0 0.4 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAG06520.1 - 0.061 12.8 0.0 0.62 9.5 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family DLH PF01738.18 AAG06520.1 - 0.13 11.7 0.1 4.1 6.9 0.0 2.6 2 1 1 3 3 3 0 Dienelactone hydrolase family Thioesterase PF00975.20 AAG06520.1 - 0.22 11.6 0.7 0.48 10.5 0.7 1.6 2 0 0 2 2 2 0 Thioesterase domain TetR_N PF00440.23 AAG06521.1 - 2.6e-08 33.5 0.2 5.5e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAG06521.1 - 0.0061 16.8 1.2 0.0061 16.8 1.2 2.4 3 0 0 3 3 3 1 BetI-type transcriptional repressor, C-terminal tRNA-synt_1c PF00749.21 AAG06522.1 - 7.8e-110 366.6 0.0 1e-109 366.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain LysR_substrate PF03466.20 AAG06523.1 - 4.1e-47 160.2 3.0 5.4e-47 159.8 3.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06523.1 - 4.9e-19 68.0 1.0 8.6e-19 67.2 1.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG06523.1 - 0.00044 20.0 0.3 0.001 18.8 0.3 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_50 PF18024.1 AAG06523.1 - 0.0019 17.8 0.2 0.1 12.2 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain Tropomyosin_1 PF12718.7 AAG06523.1 - 0.0038 17.4 0.1 0.0059 16.8 0.1 1.2 1 0 0 1 1 1 1 Tropomyosin like HTH_IclR PF09339.10 AAG06523.1 - 0.006 16.4 6.2 0.074 12.9 0.1 3.9 5 0 0 5 5 5 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AAG06523.1 - 0.033 14.2 0.2 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AAG06523.1 - 0.039 13.8 0.1 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 MarR family DUF4570 PF15134.6 AAG06523.1 - 0.078 13.0 0.6 0.19 11.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) HTH_Tnp_4 PF13613.6 AAG06523.1 - 0.097 12.4 0.1 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_24 PF13412.6 AAG06523.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HlyD_D23 PF16576.5 AAG06524.1 - 1.1e-20 73.9 6.3 1.8e-18 66.6 6.3 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG06524.1 - 1.4e-17 64.3 1.1 6.5e-15 55.7 0.0 3.3 2 2 0 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG06524.1 - 5.2e-16 58.2 7.4 2e-12 46.7 1.8 4.1 4 0 0 4 4 4 2 Biotin-lipoyl like HlyD PF00529.20 AAG06524.1 - 1.1e-08 34.8 0.2 1.8e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG06524.1 - 0.0091 15.8 0.0 0.82 9.5 0.0 2.7 2 0 0 2 2 2 1 Biotin-requiring enzyme TMF_TATA_bd PF12325.8 AAG06524.1 - 0.073 13.3 2.2 4.7 7.5 0.3 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.6 AAG06524.1 - 0.11 12.6 0.2 0.11 12.6 0.2 1.8 2 0 0 2 2 2 0 FlxA-like protein TPR_MLP1_2 PF07926.12 AAG06524.1 - 0.19 11.8 13.3 3.2 7.8 1.3 2.9 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 AAG06524.1 - 0.23 11.9 7.2 9.3 6.7 7.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) THOC7 PF05615.13 AAG06524.1 - 0.62 10.3 14.1 1.7 8.9 4.2 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 Spc7 PF08317.11 AAG06524.1 - 1.1 8.1 10.4 3.9 6.3 1.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Fil_haemagg PF05594.14 AAG06524.1 - 1.5 9.4 6.2 3.2 8.3 5.4 2.0 1 1 1 2 2 2 0 Haemagluttinin repeat FliJ PF02050.16 AAG06524.1 - 2.6 8.3 12.0 5 7.4 1.5 2.5 1 1 0 2 2 2 0 Flagellar FliJ protein ABC_tran_CTD PF16326.5 AAG06524.1 - 3.4 8.0 11.0 0.69 10.2 1.9 3.1 1 1 3 4 4 4 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 AAG06524.1 - 4.4 7.3 7.3 3.1 7.8 1.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_1 PF07690.16 AAG06525.1 - 1.2e-44 152.7 34.7 1.2e-44 152.7 34.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG06525.1 - 0.00057 18.9 9.1 0.0012 17.8 9.1 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter UvrB_inter PF17757.1 AAG06526.1 - 7.8e-33 112.5 0.0 2e-32 111.2 0.0 1.8 1 0 0 1 1 1 1 UvrB interaction domain UvrB PF12344.8 AAG06526.1 - 1.1e-22 79.6 0.1 2.3e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AAG06526.1 - 2.2e-17 63.4 0.1 5.3e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAG06526.1 - 7.2e-10 39.1 0.0 6.2e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 AAG06526.1 - 1.1e-09 37.7 7.4 4.1e-09 35.9 7.4 2.1 1 0 0 1 1 1 1 UvrB/uvrC motif DEAD PF00270.29 AAG06526.1 - 7.6e-07 29.1 0.2 0.00047 20.0 0.0 3.8 5 1 0 5 5 5 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AAG06526.1 - 0.00015 21.6 0.0 0.006 16.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain DNA_pol_A PF00476.20 AAG06526.1 - 0.015 14.3 0.5 0.44 9.5 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase family A AAA_22 PF13401.6 AAG06526.1 - 0.054 13.8 0.2 0.77 10.0 0.0 3.1 4 1 1 5 5 5 0 AAA domain AAA_19 PF13245.6 AAG06526.1 - 0.09 13.1 0.1 20 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain CdvA PF18822.1 AAG06526.1 - 0.61 9.9 4.1 7.9 6.3 0.1 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Aminotran_1_2 PF00155.21 AAG06527.1 - 7.6e-77 258.9 0.0 8.6e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TetR_C_28 PF17937.1 AAG06527.1 - 0.058 13.9 0.1 0.19 12.2 0.1 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HHH_3 PF12836.7 AAG06528.1 - 5.3e-20 71.5 0.0 6.3e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AAG06528.1 - 2.4e-08 33.4 0.2 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SSK PF03934.13 AAG06528.1 - 0.00014 21.4 0.1 0.00027 20.4 0.1 1.5 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_6 PF14579.6 AAG06528.1 - 0.00097 19.3 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AAG06528.1 - 0.0018 18.8 0.4 0.067 13.8 0.4 2.3 1 1 0 1 1 1 1 Helix-hairpin-helix domain Polysacc_synt_2 PF02719.15 AAG06529.1 - 9.3e-129 428.7 0.0 1.3e-128 428.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AAG06529.1 - 4e-14 52.7 0.1 3.2e-13 49.7 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAG06529.1 - 1.8e-10 40.7 0.1 3e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAG06529.1 - 7.8e-08 31.8 0.0 6.5e-07 28.7 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAG06529.1 - 1.1e-07 31.1 0.1 2.1e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CoA_binding_3 PF13727.6 AAG06529.1 - 1.4e-05 25.2 9.7 2.1e-05 24.6 1.1 3.2 2 1 1 3 3 3 1 CoA-binding domain NAD_binding_4 PF07993.12 AAG06529.1 - 0.00024 20.4 0.4 0.0012 18.1 0.4 2.1 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.25 AAG06529.1 - 0.0033 16.9 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.16 AAG06529.1 - 0.019 14.6 1.0 0.052 13.2 0.1 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 AAG06529.1 - 0.044 14.6 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PglD_N PF17836.1 AAG06529.1 - 0.048 14.3 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 PglD N-terminal domain TrkA_N PF02254.18 AAG06529.1 - 0.079 13.2 0.2 1.3 9.3 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain CoA_binding PF02629.19 AAG06529.1 - 0.13 13.0 0.2 0.56 10.9 0.0 2.1 3 0 0 3 3 2 0 CoA binding domain KR PF08659.10 AAG06529.1 - 0.16 11.9 0.2 0.51 10.2 0.1 1.9 2 0 0 2 2 2 0 KR domain rve PF00665.26 AAG06530.1 - 1.3e-10 41.5 0.0 1.6e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAG06530.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_1 PF01527.20 AAG06532.1 - 2.8e-10 40.4 0.0 2.9e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.12 AAG06532.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.0 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 AAG06532.1 - 0.17 11.7 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 IclR helix-turn-helix domain TFA2_Winged_2 PF18121.1 AAG06532.1 - 0.17 11.6 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Glycos_transf_4 PF00953.21 AAG06533.1 - 2.2e-32 112.2 15.8 2.2e-32 112.2 15.8 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF3382 PF11862.8 AAG06533.1 - 0.029 14.6 11.2 0.13 12.5 2.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Epimerase PF01370.21 AAG06534.1 - 1.9e-28 99.5 0.0 2.4e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAG06534.1 - 3.6e-19 69.3 0.0 7.6e-18 65.0 0.0 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AAG06534.1 - 1e-18 67.9 0.0 1.3e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAG06534.1 - 7.4e-15 54.8 0.0 9.4e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAG06534.1 - 1.6e-14 53.7 0.0 1.7e-10 40.5 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 AAG06534.1 - 4.2e-14 52.2 0.0 6.5e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 AAG06534.1 - 9.5e-07 28.6 0.0 3e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 AAG06534.1 - 0.0001 21.5 0.1 0.086 12.0 0.2 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 AAG06534.1 - 0.01 15.3 0.1 0.024 14.1 0.1 1.7 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 AAG06534.1 - 0.067 13.1 0.2 0.93 9.4 0.2 2.2 1 1 0 1 1 1 0 KR domain Glyco_transf_4 PF13439.6 AAG06535.1 - 3.5e-12 46.7 0.1 1.2e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAG06535.1 - 1e-10 42.3 0.0 4.1e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AAG06535.1 - 6.3e-09 36.4 0.0 1.6e-08 35.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAG06535.1 - 2.5e-07 30.4 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAG06535.1 - 0.00013 22.3 0.0 0.00031 21.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HAD PF12710.7 AAG06535.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Epimerase_2 PF02350.19 AAG06536.1 - 4e-113 377.8 0.0 4.6e-113 377.6 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_1_4 PF13692.6 AAG06537.1 - 4e-15 56.4 0.0 7.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAG06537.1 - 7.3e-15 54.9 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAG06537.1 - 7.9e-11 42.2 0.0 2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG06537.1 - 5.8e-09 36.2 0.0 9.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAG06537.1 - 3.4e-08 34.1 0.0 6.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AAG06537.1 - 0.0039 17.2 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like QueC PF06508.13 AAG06538.1 - 0.00093 18.7 0.0 0.0037 16.8 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AAG06538.1 - 0.008 16.0 0.1 0.025 14.4 0.1 2.0 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 AAG06538.1 - 0.043 13.5 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Asparagine synthase NAD_synthase PF02540.17 AAG06538.1 - 0.059 12.5 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD synthase His_biosynth PF00977.21 AAG06539.1 - 9.7e-69 231.3 0.0 1.1e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AAG06539.1 - 0.00049 19.3 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AAG06539.1 - 0.0048 16.3 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 AAG06539.1 - 0.012 14.9 0.1 3.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 AAG06539.1 - 0.024 13.9 0.4 0.11 11.7 0.1 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 AAG06539.1 - 0.039 13.3 0.0 6.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase Pantoate_transf PF02548.15 AAG06539.1 - 0.048 13.0 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase NanE PF04131.14 AAG06539.1 - 0.069 12.3 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase GATase PF00117.28 AAG06540.1 - 3.5e-19 69.3 0.0 4.4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 AAG06540.1 - 1.1e-08 35.1 0.1 2.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 AAG06540.1 - 1.4e-06 28.1 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 AAG06540.1 - 0.0075 16.0 0.3 0.14 11.9 0.1 2.3 2 1 0 2 2 2 1 Peptidase C26 Polysacc_synt_3 PF13440.6 AAG06541.1 - 6e-14 52.0 16.4 1.2e-13 51.0 16.4 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DegT_DnrJ_EryC1 PF01041.17 AAG06543.1 - 5.1e-119 397.8 0.0 5.8e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AAG06543.1 - 9.6e-12 44.7 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAG06543.1 - 4.7e-09 35.9 0.0 1e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAG06543.1 - 1.7e-08 33.8 0.0 2.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAG06543.1 - 2.1e-07 29.8 0.0 3.1e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 AAG06543.1 - 0.13 11.0 0.0 0.32 9.7 0.0 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Hexapep PF00132.24 AAG06544.1 - 1.1e-19 69.3 15.8 5.4e-07 29.1 0.8 3.3 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAG06544.1 - 1.2e-10 40.9 16.3 3.8e-05 23.3 2.6 4.2 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 AAG06544.1 - 0.92 7.6 3.3 0.87 7.6 1.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Acyl_transf_3 PF01757.22 AAG06545.1 - 2.4e-24 86.0 42.7 2.5e-24 86.0 40.0 2.0 2 0 0 2 2 2 1 Acyltransferase family CedA PF10729.9 AAG06545.1 - 0.077 12.8 0.1 0.5 10.2 0.0 2.3 3 0 0 3 3 3 0 Cell division activator CedA GFO_IDH_MocA PF01408.22 AAG06546.1 - 1.1e-22 81.2 0.0 1.8e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAG06546.1 - 8.5e-19 67.7 0.1 1.3e-18 67.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain UDPG_MGDP_dh_N PF03721.14 AAG06547.1 - 4.1e-50 170.0 0.0 6.5e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAG06547.1 - 3.2e-28 97.8 0.0 6.8e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAG06547.1 - 3.5e-22 78.8 0.0 4e-21 75.4 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 AAG06547.1 - 6.6e-05 23.1 0.0 0.00021 21.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAG06547.1 - 0.0098 15.3 0.2 0.048 13.0 0.1 2.2 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAG06547.1 - 0.025 14.8 0.1 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Semialdhyde_dh PF01118.24 AAG06547.1 - 0.031 14.7 0.0 8.5 6.8 0.0 2.8 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Wzz PF02706.15 AAG06548.1 - 9.7e-19 67.5 0.4 5.6e-18 65.0 0.0 2.4 3 0 0 3 3 3 1 Chain length determinant protein GNVR PF13807.6 AAG06548.1 - 8.9e-07 28.7 0.3 2e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Ribosomal_L18_c PF14204.6 AAG06548.1 - 0.02 15.8 0.3 0.046 14.7 0.3 1.5 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Phage_holin_5_2 PF16079.5 AAG06548.1 - 0.034 14.5 1.1 0.27 11.6 0.1 2.2 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Osmo_CC PF08946.10 AAG06548.1 - 0.11 12.7 5.8 0.068 13.4 3.1 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF1090 PF06476.12 AAG06548.1 - 0.22 11.6 3.0 0.33 11.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Bac_DNA_binding PF00216.21 AAG06549.1 - 2.3e-29 101.4 0.0 2.5e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAG06549.1 - 1.4e-09 38.1 0.0 1.7e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAG06549.1 - 0.00028 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-DNA_bdg PF14848.6 AAG06549.1 - 0.0013 18.8 0.0 0.0046 17.0 0.0 1.8 1 1 0 1 1 1 1 DNA-binding domain HU-CCDC81_euk_1 PF14908.6 AAG06549.1 - 0.0063 16.6 0.0 0.0073 16.4 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 S1 PF00575.23 AAG06550.1 - 7.2e-101 330.6 36.8 9.8e-22 77.1 0.3 6.1 6 0 0 6 6 6 6 S1 RNA binding domain PCB_OB PF17092.5 AAG06550.1 - 6e-11 43.1 5.7 0.065 14.0 0.1 6.0 2 1 3 6 6 6 3 Penicillin-binding protein OB-like domain S1_2 PF13509.6 AAG06550.1 - 0.00022 21.2 12.4 2.2 8.4 0.2 6.7 7 2 0 7 7 7 2 S1 domain RsgI_N PF12791.7 AAG06550.1 - 0.018 14.9 5.3 0.85 9.6 0.0 3.6 4 0 0 4 4 4 0 Anti-sigma factor N-terminus CsrA PF02599.16 AAG06550.1 - 0.019 14.9 6.9 1.5 8.8 0.1 3.9 5 0 0 5 5 5 0 Global regulator protein family DUF4314 PF14192.6 AAG06550.1 - 0.032 14.1 0.1 3.7 7.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) HupF_HypC PF01455.18 AAG06550.1 - 0.049 13.8 2.1 30 4.9 0.0 4.2 3 0 0 3 3 3 0 HupF/HypC family Succ_CoA_lig PF13607.6 AAG06550.1 - 0.061 13.1 0.0 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain SH3_1 PF00018.28 AAG06550.1 - 0.088 12.4 2.1 15 5.3 0.0 3.3 4 0 0 4 4 4 0 SH3 domain TOBE_2 PF08402.10 AAG06550.1 - 0.55 10.4 6.6 6 7.1 0.1 4.6 5 2 0 5 5 5 0 TOBE domain DUF1344 PF07076.11 AAG06550.1 - 2.7 8.0 12.5 10 6.1 0.1 5.2 7 0 0 7 7 7 0 Protein of unknown function (DUF1344) Cytidylate_kin PF02224.18 AAG06551.1 - 5.4e-77 258.3 0.1 6.2e-77 258.1 0.1 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 AAG06551.1 - 2.6e-06 27.7 0.6 1.7e-05 25.0 0.6 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 AAG06551.1 - 4.7e-05 23.9 0.1 0.00078 20.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAG06551.1 - 0.00071 20.0 0.3 0.035 14.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAG06551.1 - 0.0013 18.9 0.4 0.0065 16.6 0.4 2.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 AAG06551.1 - 0.0043 17.2 0.1 0.11 12.6 0.0 2.6 3 0 0 3 3 3 1 Shikimate kinase ADK PF00406.22 AAG06551.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 0 Adenylate kinase dNK PF01712.19 AAG06551.1 - 0.043 13.7 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.27 AAG06551.1 - 0.17 12.4 0.0 0.23 12.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Aminotran_1_2 PF00155.21 AAG06553.1 - 3e-50 171.4 0.0 3.4e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAG06553.1 - 0.0084 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V HTH_Tnp_1 PF01527.20 AAG06553.1 - 0.016 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 Transposase MarR_2 PF12802.7 AAG06553.1 - 0.034 14.0 0.0 0.71 9.8 0.0 2.6 2 0 0 2 2 2 0 MarR family E3_binding PF02817.17 AAG06553.1 - 0.04 14.3 0.1 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 e3 binding domain PDT PF00800.18 AAG06554.1 - 1.2e-62 211.0 0.1 1.5e-62 210.6 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 AAG06554.1 - 6e-23 81.0 0.2 2e-22 79.3 0.2 2.0 2 0 0 2 2 2 1 Chorismate mutase type II ACT PF01842.25 AAG06554.1 - 5.1e-11 42.2 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain HNHc_6 PF16784.5 AAG06554.1 - 0.051 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative HNHc nuclease XOO_2897-deam PF14440.6 AAG06554.1 - 0.067 13.3 0.1 1.5 9.0 0.0 2.5 2 1 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase Aminotran_5 PF00266.19 AAG06555.1 - 5e-50 170.5 0.0 5.6e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DNA_topoisoIV PF00521.20 AAG06556.1 - 1.4e-153 511.8 0.0 1.7e-153 511.5 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AAG06556.1 - 1.1e-74 245.7 6.1 1.9e-13 49.7 0.2 6.5 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller SIS PF01380.22 AAG06556.1 - 0.019 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 SIS domain IF-2B PF01008.17 AAG06557.1 - 3.1e-74 249.7 0.0 3.7e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Amidohydro_1 PF01979.20 AAG06558.1 - 6.9e-68 229.5 0.0 8.2e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG06558.1 - 1.8e-19 70.6 2.3 2.4e-17 63.6 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase family Methyltransf_23 PF13489.6 AAG06559.1 - 1.1e-27 96.8 0.0 1.6e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG06559.1 - 1.3e-22 80.2 0.0 2.1e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG06559.1 - 1.2e-19 70.8 0.1 1.8e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG06559.1 - 1.9e-17 63.5 0.0 2.4e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG06559.1 - 4.4e-17 62.6 0.0 6.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAG06559.1 - 4.4e-11 42.6 0.0 5.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 AAG06559.1 - 1.2e-10 41.1 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 AAG06559.1 - 8.2e-08 32.0 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 AAG06559.1 - 1.5e-07 31.3 0.0 2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 AAG06559.1 - 7.5e-07 29.0 0.0 2.7e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) DREV PF05219.12 AAG06559.1 - 2.8e-06 26.6 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 AAG06559.1 - 2.9e-06 27.0 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 AAG06559.1 - 1e-05 24.6 0.0 1.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 AAG06559.1 - 0.00034 20.3 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 AAG06559.1 - 0.00072 19.7 0.0 0.0018 18.4 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 AAG06559.1 - 0.0051 16.8 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 AAG06559.1 - 0.0068 15.8 0.0 0.009 15.4 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 AAG06559.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HAD_2 PF13419.6 AAG06560.1 - 1.5e-34 119.6 0.0 1.8e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG06560.1 - 1.3e-21 77.9 0.0 1.9e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG06560.1 - 1.8e-12 47.1 0.0 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAG06560.1 - 4.2e-12 46.8 0.0 6.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAG06560.1 - 0.00049 19.9 0.1 0.71 9.6 0.0 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAG06560.1 - 0.0069 16.5 0.0 0.067 13.3 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 AAG06560.1 - 0.14 11.8 0.0 6 6.4 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) adh_short PF00106.25 AAG06561.1 - 2.6e-49 167.3 0.1 3e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG06561.1 - 7.8e-40 136.9 0.1 2.1e-39 135.5 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG06561.1 - 2.6e-14 53.6 0.1 3.5e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AAG06561.1 - 0.0065 15.9 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 AAG06561.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 AAG06561.1 - 0.16 11.4 0.3 0.66 9.4 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family IclR PF01614.18 AAG06562.1 - 1.7e-15 57.0 0.1 2.8e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AAG06562.1 - 2.8e-11 43.0 0.8 2.8e-11 43.0 0.8 2.4 3 0 0 3 3 3 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAG06562.1 - 7.4e-05 22.6 0.1 0.00031 20.6 0.1 2.0 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAG06562.1 - 0.002 18.2 0.3 0.002 18.2 0.3 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.6 AAG06562.1 - 0.0065 16.0 1.4 0.017 14.6 0.1 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAG06562.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AAG06562.1 - 0.02 14.7 0.7 0.05 13.5 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AAG06562.1 - 0.05 13.5 0.6 0.26 11.3 0.1 2.3 2 0 0 2 2 2 0 HTH domain Arginase PF00491.21 AAG06563.1 - 1.2e-60 205.4 0.0 1.3e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family Glt_symporter PF03616.14 AAG06564.1 - 8.2e-150 498.6 11.0 9.4e-150 498.4 11.0 1.0 1 0 0 1 1 1 1 Sodium/glutamate symporter DUF4658 PF15555.6 AAG06564.1 - 0.0023 18.0 0.1 0.0023 18.0 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4658) GGDEF PF00990.21 AAG06565.1 - 1.4e-46 158.2 0.0 2.2e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PseudoU_synth_2 PF00849.22 AAG06567.1 - 3.1e-15 56.6 0.0 6.9e-15 55.5 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAG06567.1 - 6.7e-10 38.5 0.5 1.6e-09 37.3 0.5 1.7 1 0 0 1 1 1 1 S4 domain NUDIX PF00293.28 AAG06568.1 - 5e-12 46.0 0.1 6.4e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Aldolase PF01081.19 AAG06569.1 - 4.2e-79 264.5 0.0 4.8e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase Glucosamine_iso PF01182.20 AAG06570.1 - 1.1e-51 175.8 0.2 1.3e-51 175.7 0.2 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_C PF02781.16 AAG06571.1 - 2.5e-118 394.5 0.0 3.1e-118 394.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AAG06571.1 - 1.6e-52 178.7 0.0 2.4e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAG06571.1 - 0.015 16.1 0.0 0.028 15.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold HTH_6 PF01418.17 AAG06572.1 - 1.6e-31 108.1 0.2 2.5e-31 107.5 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 AAG06572.1 - 1.7e-21 76.5 0.3 2.7e-21 75.8 0.3 1.4 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AAG06572.1 - 1.2e-07 31.8 4.0 4.5e-05 23.5 0.1 3.1 1 1 1 3 3 3 2 SIS domain HTH_IclR PF09339.10 AAG06572.1 - 0.29 11.0 2.3 0.65 9.8 0.0 2.7 4 0 0 4 4 4 0 IclR helix-turn-helix domain Aldose_epim PF01263.20 AAG06573.1 - 7.5e-31 107.6 0.0 9.6e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase OprB PF04966.12 AAG06574.1 - 1.6e-119 399.7 8.5 1.8e-119 399.5 8.5 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family ABC_tran PF00005.27 AAG06575.1 - 2.2e-32 112.4 0.0 3.3e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 AAG06575.1 - 6.9e-12 46.0 0.1 2.9e-11 44.0 0.1 2.2 1 0 0 1 1 1 1 MalK OB fold domain TOBE PF03459.17 AAG06575.1 - 1.5e-09 38.0 0.1 7.2e-09 35.8 0.0 2.2 3 0 0 3 3 2 1 TOBE domain AAA_21 PF13304.6 AAG06575.1 - 1.4e-08 34.9 0.2 0.0034 17.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 AAG06575.1 - 6.3e-08 32.7 0.3 5.4e-07 29.7 0.1 2.4 2 0 0 2 2 2 1 TOBE domain RsgA_GTPase PF03193.16 AAG06575.1 - 2.7e-05 24.2 0.2 0.00014 21.8 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AAG06575.1 - 4e-05 23.2 0.3 0.00032 20.2 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG06575.1 - 0.00026 21.4 0.1 0.00043 20.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG06575.1 - 0.00069 19.3 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG06575.1 - 0.0028 18.2 0.0 0.0049 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG06575.1 - 0.0036 17.6 0.2 0.0087 16.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAG06575.1 - 0.0044 17.0 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain CysA_C_terminal PF17850.1 AAG06575.1 - 0.01 16.4 0.0 0.028 15.0 0.0 1.8 1 0 0 1 1 1 0 CysA C-terminal regulatory domain AAA_25 PF13481.6 AAG06575.1 - 0.024 14.2 0.0 0.069 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAG06575.1 - 0.026 14.9 0.0 0.071 13.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAG06575.1 - 0.039 14.0 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 AAG06575.1 - 0.04 13.6 0.0 0.068 12.9 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 AAG06575.1 - 0.053 13.2 0.0 0.098 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAG06575.1 - 0.064 13.7 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 AAG06575.1 - 0.07 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_S17 PF00366.20 AAG06575.1 - 0.1 12.7 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S17 AAA_33 PF13671.6 AAG06575.1 - 0.14 12.3 0.2 0.25 11.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAG06575.1 - 0.17 11.1 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 AAG06575.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea BPD_transp_1 PF00528.22 AAG06576.1 - 1.7e-13 50.7 18.2 1.7e-13 50.7 18.2 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component TCR_zetazeta PF11628.8 AAG06576.1 - 0.13 11.9 0.7 0.4 10.4 0.7 1.8 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain BPD_transp_1 PF00528.22 AAG06577.1 - 1.4e-11 44.5 14.7 1.4e-11 44.5 14.7 2.0 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF347 PF03988.12 AAG06577.1 - 0.064 13.4 2.5 1.5 9.0 0.3 2.9 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) YesK PF14150.6 AAG06577.1 - 5.6 7.2 9.0 4.8 7.4 0.7 3.4 3 0 0 3 3 3 0 YesK-like protein SBP_bac_1 PF01547.25 AAG06578.1 - 1.3e-26 94.3 10.9 2e-26 93.7 10.9 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAG06578.1 - 1.2e-21 77.8 6.9 1.2e-21 77.8 6.9 1.9 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein HATPase_c PF02518.26 AAG06579.1 - 1.6e-17 64.0 0.0 3.8e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAG06579.1 - 6.9e-10 39.2 1.0 6.9e-10 39.2 1.0 2.3 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 AAG06579.1 - 1.7e-08 34.4 0.8 5.5e-08 32.7 0.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAG06579.1 - 0.061 13.2 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 GHKL domain Response_reg PF00072.24 AAG06580.1 - 3.7e-28 97.9 0.0 5.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG06580.1 - 1.2e-18 66.9 0.0 2.3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AAG06580.1 - 0.0025 18.2 0.0 0.005 17.2 0.0 1.6 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Glucokinase PF02685.16 AAG06581.1 - 7.8e-106 353.6 0.9 8.9e-106 353.5 0.9 1.0 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 AAG06581.1 - 0.0024 17.4 0.0 0.0074 15.8 0.0 1.7 1 1 0 1 1 1 1 ROK family ILVD_EDD PF00920.21 AAG06582.1 - 3.7e-162 540.6 0.0 4.3e-162 540.3 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family zf-A20 PF01754.16 AAG06582.1 - 0.29 11.1 0.9 0.8 9.7 0.9 1.8 1 0 0 1 1 1 0 A20-like zinc finger Gp_dh_C PF02800.20 AAG06583.1 - 2.7e-61 205.8 0.0 3.5e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AAG06583.1 - 4.9e-38 129.5 0.0 9.6e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AAG06583.1 - 0.03 15.0 0.0 0.099 13.3 0.0 1.9 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 AAG06583.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SMC_ScpB PF04079.16 AAG06585.1 - 1.7e-49 167.5 0.0 2.6e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB PSD5 PF07637.11 AAG06585.1 - 0.062 13.7 0.0 2.5 8.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) SMC_ScpA PF02616.14 AAG06586.1 - 8.5e-31 107.7 7.9 6e-22 78.7 1.7 2.1 2 0 0 2 2 2 2 Segregation and condensation protein ScpA Rad21_Rec8 PF04824.16 AAG06586.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Sua5_yciO_yrdC PF01300.18 AAG06587.1 - 1.8e-44 151.4 0.0 2e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination PHP PF02811.19 AAG06588.1 - 4.6e-10 40.1 0.0 4.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 PHP domain IspA PF04279.15 AAG06589.1 - 1.7e-60 204.2 11.8 1.9e-60 204.0 11.8 1.0 1 0 0 1 1 1 1 Intracellular septation protein A DUF2368 PF10166.9 AAG06589.1 - 0.32 10.6 0.6 0.84 9.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) DUF1304 PF06993.12 AAG06589.1 - 0.49 10.4 5.1 0.35 10.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) DUF962 PF06127.11 AAG06589.1 - 2.9 8.0 6.4 2 8.6 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF962) YCII PF03795.14 AAG06590.1 - 5.2e-30 103.7 0.0 5.7e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF1330 PF07045.11 AAG06590.1 - 0.013 15.8 0.2 0.029 14.7 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1330) DUF5094 PF17015.5 AAG06591.1 - 0.022 14.8 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) RdRP_5 PF07925.11 AAG06591.1 - 0.041 11.3 0.1 0.045 11.1 0.1 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 GAS PF13851.6 AAG06591.1 - 0.075 12.4 3.1 0.1 11.9 3.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 AAG06591.1 - 0.24 11.5 7.6 0.32 11.1 7.2 1.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RskA PF10099.9 AAG06591.1 - 5.6 7.2 12.1 69 3.7 11.8 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Response_reg PF00072.24 AAG06592.1 - 1e-27 96.5 0.0 1.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG06592.1 - 2.2e-16 59.7 0.2 5.2e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AAG06592.1 - 0.0011 19.3 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Thump_like PF18096.1 AAG06592.1 - 0.12 12.4 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 THUMP domain-like LTXXQ PF07813.12 AAG06593.1 - 1.1e-06 29.3 10.9 1.1e-06 29.3 10.9 2.5 2 1 0 2 2 2 1 LTXXQ motif family protein Metal_resist PF13801.6 AAG06593.1 - 0.0013 18.9 4.0 0.0013 18.9 4.0 3.0 1 1 2 3 3 3 2 Heavy-metal resistance PYC_OADA PF02436.18 AAG06593.1 - 0.03 14.1 1.0 0.035 13.9 1.0 1.1 1 0 0 1 1 1 0 Conserved carboxylase domain Muted PF14942.6 AAG06593.1 - 0.039 14.3 12.1 0.049 14.0 12.1 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1682 PF07946.14 AAG06593.1 - 0.076 12.2 15.3 0.091 12.0 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3974 PF13120.6 AAG06593.1 - 0.093 12.8 1.4 0.16 12.1 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) HATPase_c PF02518.26 AAG06594.1 - 1.8e-19 70.3 0.0 3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG06594.1 - 1e-11 44.7 2.3 1e-11 44.7 2.3 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAG06594.1 - 3e-10 40.3 1.8 1.1e-09 38.5 1.8 2.1 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 AAG06594.1 - 0.00011 22.2 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF948 PF06103.11 AAG06594.1 - 0.052 13.8 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2576 PF10845.8 AAG06594.1 - 0.06 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) UPF0016 PF01169.19 AAG06594.1 - 0.13 12.6 1.5 0.18 12.2 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 DUF4389 PF14333.6 AAG06594.1 - 0.77 9.7 3.0 0.78 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF2599 PF10783.9 AAG06595.1 - 0.049 14.3 0.1 0.078 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2599) Nitroreductase PF00881.24 AAG06596.1 - 1.2e-23 84.0 0.0 1.4e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family CxxCxxCC PF03692.15 AAG06597.1 - 4.2e-12 46.6 3.5 6e-12 46.1 3.5 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF3443 PF11925.8 AAG06597.1 - 0.031 13.1 0.3 0.059 12.2 0.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3443) TrkH PF02386.16 AAG06598.1 - 1.5e-57 195.2 14.1 3.3e-56 190.8 14.1 2.0 1 1 0 1 1 1 1 Cation transport protein MlaE PF02405.16 AAG06599.1 - 1e-66 224.7 21.1 1e-66 224.7 21.1 1.4 2 0 0 2 2 2 1 Permease MlaE STAS_2 PF13466.6 AAG06599.1 - 9.9e-05 22.6 2.6 0.00026 21.3 2.6 1.8 1 0 0 1 1 1 1 STAS domain Mito_fiss_reg PF05308.11 AAG06599.1 - 0.3 11.1 0.0 0.39 10.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator ABC_tran PF00005.27 AAG06600.1 - 9.3e-29 100.7 0.0 1.4e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06600.1 - 2.6e-09 37.3 0.1 8.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG06600.1 - 0.0045 17.4 3.1 0.035 14.5 3.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AAG06600.1 - 0.085 12.6 0.2 6.7 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAG06600.1 - 0.097 12.4 0.2 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AAG06600.1 - 0.1 11.9 0.0 0.85 8.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 AAG06600.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_ATPase PF09818.9 AAG06600.1 - 0.13 11.0 1.9 4.3 6.0 0.1 2.5 2 1 1 3 3 3 0 Predicted ATPase of the ABC class T2SSE PF00437.20 AAG06600.1 - 0.14 11.2 0.0 0.45 9.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 AAG06600.1 - 0.15 12.3 2.1 0.87 9.9 1.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 AAG06600.1 - 0.18 11.6 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MlaD PF02470.20 AAG06601.1 - 2.4e-11 43.8 0.1 5.3e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 MlaD protein DUF948 PF06103.11 AAG06601.1 - 0.00052 20.2 1.6 0.13 12.6 0.5 3.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 AAG06601.1 - 0.0017 18.0 1.7 0.0022 17.7 1.7 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit PLU-1 PF08429.11 AAG06601.1 - 0.0026 17.0 0.3 0.0035 16.6 0.3 1.3 1 0 0 1 1 1 1 PLU-1-like protein KASH_CCD PF14662.6 AAG06601.1 - 0.014 15.2 4.1 1.7 8.5 4.5 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Dor1 PF04124.12 AAG06601.1 - 0.025 13.3 3.6 0.039 12.6 3.6 1.2 1 0 0 1 1 1 0 Dor1-like family Laminin_II PF06009.12 AAG06601.1 - 0.028 14.4 3.6 7.1 6.6 0.0 2.6 2 1 1 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.9 AAG06601.1 - 0.051 13.9 1.7 7.4 6.9 0.0 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.12 AAG06601.1 - 0.056 11.6 0.1 0.077 11.2 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 AAG06601.1 - 0.064 12.1 1.7 0.088 11.7 1.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2524 PF10732.9 AAG06601.1 - 0.065 13.5 3.2 0.14 12.5 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) DUF4407 PF14362.6 AAG06601.1 - 0.073 12.4 4.6 0.12 11.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) kleA_kleC PF17383.2 AAG06601.1 - 0.086 13.2 4.5 1.5 9.2 3.6 2.8 1 1 0 1 1 1 0 Uncharacterized KorC regulated protein A Pex19 PF04614.12 AAG06601.1 - 0.093 12.5 2.6 0.13 12.1 2.6 1.1 1 0 0 1 1 1 0 Pex19 protein family FUSC PF04632.12 AAG06601.1 - 0.2 10.1 7.1 0.33 9.4 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin-6_N PF09177.11 AAG06601.1 - 0.29 11.7 1.9 15 6.2 0.1 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CorA PF01544.18 AAG06601.1 - 0.71 9.1 3.5 1.4 8.2 1.1 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein APG6_N PF17675.1 AAG06601.1 - 0.8 10.2 4.6 1.9 9.0 2.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Mce4_CUP1 PF11887.8 AAG06601.1 - 2.5 7.5 6.1 2.8 7.3 2.1 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative KxDL PF10241.9 AAG06601.1 - 3.1 8.1 5.8 34 4.8 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein MobC PF05713.11 AAG06601.1 - 4.1 7.9 8.7 38 4.8 0.2 4.0 3 1 1 4 4 4 0 Bacterial mobilisation protein (MobC) ABC_trans_aux PF03886.13 AAG06602.1 - 2.2e-25 89.1 0.8 2.9e-25 88.7 0.8 1.2 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component Arabinose_bd PF12625.7 AAG06603.1 - 1.1e-45 156.0 6.8 1.1e-45 156.0 6.8 2.2 2 1 1 3 3 3 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG06603.1 - 1.8e-22 79.4 0.6 1.8e-22 79.4 0.6 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06603.1 - 6.1e-16 58.1 0.1 8.3e-10 38.5 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family SurA_N PF09312.11 AAG06603.1 - 0.011 15.8 0.2 0.021 14.9 0.2 1.4 1 0 0 1 1 1 0 SurA N-terminal domain HTH_23 PF13384.6 AAG06603.1 - 0.042 13.7 1.2 0.24 11.3 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_30 PF13556.6 AAG06603.1 - 0.048 13.5 0.3 0.19 11.6 0.3 2.1 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAG06603.1 - 0.29 11.3 2.1 0.71 10.0 0.2 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain DUF962 PF06127.11 AAG06604.1 - 6.2e-38 128.8 4.1 6.9e-38 128.6 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Guanylate_cyc PF00211.20 AAG06605.1 - 8.4e-40 136.3 0.2 1.3e-39 135.7 0.2 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MASE2 PF05230.11 AAG06605.1 - 6.8e-30 103.0 2.5 1.7e-29 101.7 2.5 1.7 1 0 0 1 1 1 1 MASE2 domain Antiterm PF03589.13 AAG06605.1 - 0.029 14.7 0.0 0.25 11.7 0.0 2.5 3 0 0 3 3 3 0 Antitermination protein DivIC PF04977.15 AAG06605.1 - 0.059 13.1 2.6 0.27 11.0 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF2070 PF09843.9 AAG06605.1 - 8.8 4.5 10.7 12 4.0 7.9 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Metallophos_2 PF12850.7 AAG06607.1 - 2e-14 54.1 0.8 1.2e-13 51.6 0.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAG06607.1 - 3e-09 37.7 4.7 5.9e-09 36.7 4.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Attractin PF08037.11 AAG06607.1 - 0.13 12.2 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 Attractin family HTH_18 PF12833.7 AAG06608.1 - 5.7e-22 77.8 3.2 1.3e-21 76.6 2.5 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06608.1 - 1.9e-16 59.7 0.0 1.1e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG06608.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MarR_2 PF12802.7 AAG06608.1 - 0.11 12.5 2.2 12 5.8 0.1 3.6 3 1 1 4 4 4 0 MarR family tRNA_bind PF01588.20 AAG06609.1 - 2.4e-17 62.8 0.0 2.7e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain EamA PF00892.20 AAG06610.1 - 5.2e-33 114.1 42.4 4.7e-21 75.4 16.9 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AAG06610.1 - 0.00011 21.7 8.2 0.037 13.4 1.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Flavodoxin_2 PF02525.17 AAG06611.1 - 2.4e-49 167.7 0.0 2.8e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAG06611.1 - 1.4e-11 44.3 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase LysR_substrate PF03466.20 AAG06613.1 - 6.5e-26 91.0 2.6 1.2e-25 90.2 2.6 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06613.1 - 5e-19 68.0 0.3 1.3e-18 66.7 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG06613.1 - 2.2e-05 24.2 0.1 5.6e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG06613.1 - 9.4e-05 22.2 0.1 0.00027 20.7 0.1 1.8 1 0 0 1 1 1 1 MarR family Abhydrolase_6 PF12697.7 AAG06614.1 - 3e-27 96.7 0.6 3.8e-27 96.3 0.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG06614.1 - 1.1e-26 94.1 0.0 1.9e-22 80.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06614.1 - 9e-15 54.6 0.0 1.6e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAG06614.1 - 0.0085 16.2 0.0 0.017 15.3 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Antimicrobial24 PF16049.5 AAG06614.1 - 0.026 14.5 0.3 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide Abhydro_lipase PF04083.16 AAG06614.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.16 AAG06614.1 - 0.034 14.0 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2048 PF09752.9 AAG06614.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_4 PF08386.10 AAG06614.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein HTH_38 PF13936.6 AAG06614.1 - 1.9 8.3 4.1 1.2 8.9 0.8 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Pro_isomerase PF00160.21 AAG06615.1 - 1.4e-47 161.9 0.1 1.6e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ABC_tran PF00005.27 AAG06616.1 - 1.3e-34 119.7 0.0 2.2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAG06616.1 - 8.4e-15 55.1 8.3 1.3e-14 54.5 8.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAG06616.1 - 8.4e-08 31.9 0.0 2.6e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AAG06616.1 - 0.00011 22.3 0.0 0.00037 20.6 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAG06616.1 - 0.00051 20.0 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAG06616.1 - 0.001 19.5 0.9 0.0041 17.5 0.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAG06616.1 - 0.0014 18.9 0.3 0.038 14.3 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG06616.1 - 0.0035 17.1 1.0 0.014 15.1 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 AAG06616.1 - 0.0075 16.7 0.1 4.2 7.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AAG06616.1 - 0.0086 16.0 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 AAG06616.1 - 0.013 16.1 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAG06616.1 - 0.021 14.6 0.1 0.076 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAG06616.1 - 0.061 13.1 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 AAG06616.1 - 0.064 13.1 0.4 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 AAG06616.1 - 0.087 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAG06616.1 - 0.088 12.8 1.2 0.33 11.0 0.5 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 AAG06616.1 - 0.16 11.6 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 AAG06616.1 - 0.18 11.9 0.2 0.39 10.8 0.1 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2790 PF10976.8 AAG06617.1 - 3.3e-26 91.1 0.0 3.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2790) Ependymin PF00811.18 AAG06617.1 - 0.17 12.1 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 Ependymin FemAB_like PF04339.12 AAG06618.1 - 3.6e-148 493.6 0.0 4.1e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 AAG06618.1 - 2.2e-12 47.3 2.4 2.2e-12 47.3 2.4 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain DUF3309 PF11752.8 AAG06619.1 - 4.4e-21 74.7 19.9 4.8e-21 74.5 19.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3309) PDGLE PF13190.6 AAG06619.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 PDGLE domain RNase_T PF00929.24 AAG06620.1 - 5.9e-19 69.2 0.0 7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAG06620.1 - 3.7e-07 30.3 0.0 3.1e-06 27.3 0.0 2.4 1 1 1 2 2 2 1 3' exoribonuclease, RNase T-like RNase_H_2 PF13482.6 AAG06620.1 - 0.0071 16.4 0.0 0.13 12.2 0.0 2.0 1 1 0 1 1 1 1 RNase_H superfamily DUF294 PF03445.13 AAG06621.1 - 5e-42 143.0 0.0 7.7e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 DUF294_C PF10335.9 AAG06621.1 - 2.9e-39 134.1 5.1 8.5e-39 132.6 3.6 2.4 2 0 0 2 2 2 1 Putative nucleotidyltransferase substrate binding domain cNMP_binding PF00027.29 AAG06621.1 - 6.3e-10 39.0 0.1 2e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain CBS PF00571.28 AAG06621.1 - 1.3e-09 38.3 0.1 0.0023 18.3 0.0 2.9 2 0 0 2 2 2 2 CBS domain FIST_C PF10442.9 AAG06621.1 - 0.035 14.1 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 FIST C domain SSF PF00474.17 AAG06622.1 - 6.7e-129 430.3 36.1 8.5e-129 430.0 36.1 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 AAG06622.1 - 0.18 12.4 0.1 0.18 12.4 0.1 3.2 4 1 0 4 4 4 0 Protein of unknown function (DUF2818) DUF2784 PF10861.8 AAG06622.1 - 1.6 8.8 13.8 0.68 10.0 6.1 3.4 3 0 0 3 3 3 0 Protein of Unknown function (DUF2784) DUF485 PF04341.12 AAG06623.1 - 1.4e-33 114.6 0.0 1.6e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF485 DUF2663 PF10864.8 AAG06623.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2207 PF09972.9 AAG06623.1 - 0.14 10.9 0.1 0.14 10.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CbtB PF09489.10 AAG06623.1 - 0.16 12.1 1.4 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) OpuAC PF04069.12 AAG06624.1 - 4.5e-61 206.7 5.9 5.3e-61 206.4 5.9 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_3 PF00497.20 AAG06624.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF2061 PF09834.9 AAG06625.1 - 5.5e-22 78.0 2.5 6.3e-22 77.8 2.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2061) PTS_EIIC PF02378.18 AAG06625.1 - 0.019 14.0 0.1 0.019 14.0 0.1 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Abhydrolase_6 PF12697.7 AAG06626.1 - 1e-06 29.6 0.0 8.4e-06 26.5 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG06626.1 - 0.06 13.0 0.3 17 5.0 0.1 2.9 2 1 1 3 3 3 0 alpha/beta hydrolase fold MlaA PF04333.13 AAG06627.1 - 9.5e-68 227.8 0.3 1.1e-67 227.5 0.3 1.1 1 0 0 1 1 1 1 MlaA lipoprotein Pirin PF02678.16 AAG06628.1 - 7.1e-38 128.9 0.6 1.3e-37 128.1 0.1 1.7 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 AAG06628.1 - 2.4e-33 114.6 0.0 1.1e-32 112.5 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 AAG06628.1 - 0.022 14.5 0.4 1.7 8.4 0.2 2.7 2 0 0 2 2 2 0 Cupin domain Pirin_C_2 PF17954.1 AAG06628.1 - 0.089 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Patatin PF01734.22 AAG06629.1 - 1.6e-23 84.0 3.2 3.3e-23 83.0 3.2 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Lip_A_acyltrans PF03279.13 AAG06630.1 - 1.6e-87 293.4 0.0 1.8e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase MinC_C PF03775.16 AAG06631.1 - 4.9e-30 103.5 0.1 7.2e-30 103.0 0.1 1.2 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain MinC_N PF05209.13 AAG06631.1 - 6e-30 103.3 0.0 8.3e-30 102.8 0.0 1.2 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain CbiA PF01656.23 AAG06632.1 - 6.3e-20 71.5 0.2 8.8e-20 71.1 0.2 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAG06632.1 - 1.1e-18 67.8 0.1 2.2e-18 66.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 AAG06632.1 - 1.7e-15 57.1 0.9 9.6e-15 54.7 0.9 2.2 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAG06632.1 - 1e-08 34.8 0.6 1.9e-08 33.9 0.6 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AAG06632.1 - 1.3e-07 31.1 2.2 4.1e-07 29.5 0.9 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AAG06632.1 - 3.3e-07 30.0 0.3 1.3e-06 28.0 0.3 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AAG06632.1 - 0.00077 19.0 0.8 0.038 13.4 0.6 2.4 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 AAG06632.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 AAG06632.1 - 0.041 13.7 0.2 0.096 12.5 0.2 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 AAG06632.1 - 0.099 12.3 2.7 0.54 9.9 1.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_26 PF13500.6 AAG06632.1 - 0.45 10.3 4.2 37 4.1 4.2 2.8 1 1 0 1 1 1 0 AAA domain MinE PF03776.14 AAG06633.1 - 6.8e-28 96.5 0.2 7.7e-28 96.3 0.2 1.0 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE PseudoU_synth_2 PF00849.22 AAG06634.1 - 2.8e-30 105.5 0.0 3.5e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_M18 PF02127.15 AAG06635.1 - 9e-138 459.7 0.0 1e-137 459.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 AAG06635.1 - 6.3e-11 41.8 0.1 1.5e-05 24.1 0.0 2.9 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase UxaE PF16257.5 AAG06635.1 - 0.29 9.7 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 tagaturonate epimerase Acetyltransf_3 PF13302.7 AAG06636.1 - 4.8e-18 66.2 0.0 6.2e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG06636.1 - 0.00016 21.8 0.0 0.00022 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAG06636.1 - 0.0042 16.8 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG06636.1 - 0.033 14.3 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UTRA PF07702.13 AAG06637.1 - 8e-38 129.5 0.4 1.1e-37 129.1 0.4 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAG06637.1 - 3.6e-17 61.8 0.2 7e-17 60.8 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAG06637.1 - 0.026 14.5 0.1 0.057 13.4 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain SBP_bac_6 PF13343.6 AAG06638.1 - 9.3e-35 120.2 1.0 1.4e-34 119.6 1.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAG06638.1 - 8.9e-16 58.5 4.5 8.9e-16 58.5 4.5 1.7 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG06638.1 - 1.8e-09 37.7 0.2 4.2e-09 36.5 0.0 1.6 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG06638.1 - 8.3e-07 29.3 5.0 8.3e-07 29.3 5.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Phosphodiest PF01663.22 AAG06639.1 - 1.5e-17 64.2 0.1 1e-15 58.2 0.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 AAG06639.1 - 5.2e-06 26.0 0.1 1.1e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily PglZ PF08665.12 AAG06639.1 - 0.018 15.2 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 PglZ domain AstB PF04996.12 AAG06639.1 - 0.048 12.3 0.0 0.094 11.4 0.0 1.4 2 0 0 2 2 2 0 Succinylarginine dihydrolase BPD_transp_1 PF00528.22 AAG06640.1 - 5.9e-12 45.7 16.2 5.9e-12 45.7 16.2 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG06641.1 - 1.4e-15 57.5 11.0 1.4e-15 57.5 11.0 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component NADH_oxidored PF08040.11 AAG06641.1 - 0.056 13.2 0.7 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 MNLL subunit ABC_tran PF00005.27 AAG06642.1 - 3.1e-35 121.7 0.0 1.2e-34 119.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAG06642.1 - 1.6e-10 41.3 0.3 8e-05 22.6 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 AAG06642.1 - 8.1e-09 35.5 0.1 2.3e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 TOBE domain SMC_N PF02463.19 AAG06642.1 - 0.00018 21.0 0.0 0.003 17.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG06642.1 - 0.00039 20.8 2.2 0.0017 18.8 2.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG06642.1 - 0.0013 18.6 0.0 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 AAG06642.1 - 0.0035 17.0 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AAG06642.1 - 0.0045 17.5 0.3 0.0079 16.7 0.0 1.5 2 0 0 2 2 1 1 AAA domain sCache_3_2 PF17203.4 AAG06642.1 - 0.0077 16.4 0.5 0.021 14.9 0.1 1.8 2 0 0 2 2 2 1 Single cache domain 3 AAA_29 PF13555.6 AAG06642.1 - 0.0083 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG06642.1 - 0.011 16.0 0.8 0.07 13.4 0.8 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAG06642.1 - 0.018 15.2 0.2 0.09 12.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAG06642.1 - 0.019 14.4 0.0 0.051 12.9 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAG06642.1 - 0.022 15.2 0.1 0.071 13.5 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 AAG06642.1 - 0.031 13.1 0.1 0.49 9.1 0.0 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 AAG06642.1 - 0.031 14.0 0.0 0.073 12.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 AAG06642.1 - 0.063 13.3 0.1 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAG06642.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 AAG06642.1 - 0.079 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 AAG06642.1 - 0.13 11.7 0.1 2.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DUF2738 PF10927.8 AAG06642.1 - 0.17 11.0 0.0 0.32 10.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2738) HAD PF12710.7 AAG06643.1 - 4.2e-26 92.5 0.1 5e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 AAG06644.1 - 2.1e-19 69.8 0.1 7.4e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAG06644.1 - 8.2e-13 49.6 0.1 1.5e-12 48.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG06644.1 - 7.6e-09 35.4 0.0 6.8e-07 29.1 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain TSP_NTD PF17804.1 AAG06645.1 - 1.7e-62 211.1 4.5 1.7e-62 211.1 4.5 2.0 2 0 0 2 2 2 1 Tail specific protease N-terminal domain Peptidase_S41 PF03572.18 AAG06645.1 - 2.5e-51 173.5 0.1 4.3e-51 172.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S41 DUF3340 PF11818.8 AAG06645.1 - 6e-37 127.2 7.8 6e-37 127.2 7.8 2.2 2 0 0 2 2 2 1 C-terminal domain of tail specific protease (DUF3340) PDZ PF00595.24 AAG06645.1 - 5.7e-10 39.4 0.6 1.2e-09 38.4 0.6 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AAG06645.1 - 0.044 14.1 0.7 0.16 12.4 0.7 2.0 1 1 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 AAG06645.1 - 0.087 12.7 0.2 0.28 11.1 0.2 1.9 1 1 0 1 1 1 0 PDZ domain Pox_VLTF3 PF04947.14 AAG06645.1 - 0.1 12.3 0.2 0.1 12.3 0.2 1.7 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like EAL PF00563.20 AAG06646.1 - 2.2e-56 191.0 0.0 3.6e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG06646.1 - 9e-15 54.8 0.0 7.5e-14 51.8 0.0 2.3 2 1 0 2 2 2 1 Diguanylate cyclase, GGDEF domain CBS PF00571.28 AAG06646.1 - 1.1e-07 32.1 0.7 2.9e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 CBS domain Sel1 PF08238.12 AAG06647.1 - 0.00055 20.5 19.7 0.0009 19.8 0.5 4.0 5 0 0 5 5 5 3 Sel1 repeat HTH_3 PF01381.22 AAG06648.1 - 2.7e-13 49.8 0.3 3.7e-13 49.3 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAG06648.1 - 1.2e-11 44.8 1.8 1.2e-11 44.8 1.8 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG06648.1 - 6.1e-08 32.6 0.1 8e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AAG06648.1 - 1.4e-07 31.2 0.6 2.2e-07 30.6 0.6 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06648.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.5 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAG06648.1 - 0.04 13.7 0.3 0.079 12.8 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain PhdYeFM_antitox PF02604.19 AAG06648.1 - 0.051 13.4 0.3 0.16 11.8 0.0 1.9 2 1 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system HTH_35 PF13693.6 AAG06648.1 - 0.11 12.6 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SBP_bac_3 PF00497.20 AAG06649.1 - 1.5e-15 57.3 0.0 1.7e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HypD PF01924.16 AAG06649.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family FKBP_N PF01346.18 AAG06650.1 - 1.1e-26 93.7 4.8 1.5e-26 93.2 4.8 1.2 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FKBP_C PF00254.28 AAG06650.1 - 4.1e-26 91.1 0.0 1e-25 89.9 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase RdgC PF04381.12 AAG06651.1 - 3e-115 384.6 0.3 3.4e-115 384.4 0.3 1.0 1 0 0 1 1 1 1 Putative exonuclease, RdgC SBF PF01758.16 AAG06652.1 - 8e-44 149.7 15.2 1.2e-43 149.0 15.2 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 AAG06652.1 - 2.1e-19 70.0 23.7 2.5e-19 69.7 23.7 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 AAG06652.1 - 0.46 8.8 13.0 0.074 11.4 5.1 2.3 2 1 0 2 2 2 0 Membrane transport protein Multi_Drug_Res PF00893.19 AAG06653.1 - 2.1e-28 98.8 9.0 2.6e-28 98.5 9.0 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAG06653.1 - 1.2 9.3 13.9 2.2 8.5 13.9 1.5 1 1 0 1 1 1 0 EamA-like transporter family DUF3367 PF11847.8 AAG06653.1 - 7.1 4.4 8.6 4.8 4.9 7.2 1.4 1 1 1 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase CSD PF00313.22 AAG06654.1 - 2.3e-28 97.8 3.0 2.5e-28 97.7 3.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAG06654.1 - 0.0023 17.6 0.1 0.004 16.8 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain Acyltransferase PF01553.21 AAG06655.1 - 1.2e-23 83.2 0.0 2.5e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase MFS_1 PF07690.16 AAG06655.1 - 9.2e-17 61.0 30.5 9.2e-17 61.0 30.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2985 PF11204.8 AAG06655.1 - 0.051 13.7 7.0 0.14 12.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) TonB_dep_Rec PF00593.24 AAG06656.1 - 8.3e-56 190.8 37.8 8.3e-56 190.8 37.8 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG06656.1 - 2.3e-21 76.4 7.5 2.8e-21 76.1 4.3 2.8 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG06656.1 - 5.1e-09 35.6 2.9 1.4e-08 34.2 0.1 2.4 2 1 0 2 2 2 1 Outer membrane protein beta-barrel family AraC_binding PF02311.19 AAG06657.1 - 2.8e-28 98.5 3.4 2.8e-28 98.5 3.4 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain HTH_18 PF12833.7 AAG06657.1 - 3.2e-25 88.2 0.9 3.2e-25 88.2 0.9 2.8 3 1 1 4 4 4 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06657.1 - 9.4e-18 63.9 0.0 1.5e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r3 PF04539.16 AAG06657.1 - 0.15 12.2 0.0 0.59 10.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 region 3 DUF1876 PF08962.11 AAG06657.1 - 1.7 8.7 5.6 1.1 9.3 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1876) Acetyltransf_3 PF13302.7 AAG06658.1 - 3.7e-11 43.8 0.0 4.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kelch_4 PF13418.6 AAG06658.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Galactose oxidase, central domain PAS_7 PF12860.7 AAG06659.1 - 6.7e-46 155.2 0.0 4e-45 152.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold HATPase_c PF02518.26 AAG06659.1 - 4.4e-21 75.5 0.0 1.1e-20 74.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG06659.1 - 1e-12 47.9 1.0 1e-12 47.9 1.0 2.5 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAG06659.1 - 2.5e-11 43.7 0.0 6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 AAG06659.1 - 0.00014 21.8 0.0 0.00062 19.7 0.0 2.2 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAG06659.1 - 0.0082 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS PF00989.25 AAG06659.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold OmpH PF03938.14 AAG06659.1 - 0.048 14.0 2.4 0.1 13.0 2.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATG_C PF09333.11 AAG06659.1 - 0.11 12.9 0.3 0.39 11.1 0.3 1.9 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain TMCO5 PF14992.6 AAG06659.1 - 0.12 11.9 1.2 0.19 11.2 1.2 1.2 1 0 0 1 1 1 0 TMCO5 family IFT57 PF10498.9 AAG06659.1 - 0.31 10.0 3.5 0.47 9.4 3.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF745 PF05335.13 AAG06659.1 - 0.6 9.8 13.4 3.4 7.4 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Prefoldin PF02996.17 AAG06659.1 - 1.6 8.7 3.7 9.9 6.1 2.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit DEAD_assoc PF08494.11 AAG06660.1 - 1.4e-49 168.5 0.0 3.1e-49 167.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/H associated DEAD PF00270.29 AAG06660.1 - 5.7e-26 91.3 0.0 2.4e-25 89.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG06660.1 - 4.4e-19 68.9 0.0 9.7e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAG06660.1 - 2.9e-06 27.4 0.0 6.3e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MarR_2 PF12802.7 AAG06660.1 - 0.0061 16.4 5.1 3.9 7.4 0.1 4.1 3 0 0 3 3 3 2 MarR family AAA_25 PF13481.6 AAG06660.1 - 0.035 13.7 0.1 0.16 11.5 0.1 2.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAG06660.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein HTH_20 PF12840.7 AAG06660.1 - 1.5 9.0 5.2 4 7.6 0.0 4.1 4 0 0 4 4 4 0 Helix-turn-helix domain DprA_WH PF17782.1 AAG06660.1 - 2.2 8.5 15.4 0.39 10.9 0.6 4.0 4 0 0 4 4 4 0 DprA winged helix domain PET117 PF15786.5 AAG06662.1 - 0.033 14.5 0.8 0.052 13.8 0.8 1.4 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial COG2 PF06148.11 AAG06662.1 - 0.044 13.9 2.4 0.055 13.6 2.4 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4381 PF14316.6 AAG06662.1 - 0.061 13.6 0.1 0.069 13.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RXLR PF16810.5 AAG06662.1 - 0.064 13.7 0.4 0.075 13.5 0.4 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity CHD5 PF04420.14 AAG06662.1 - 0.14 12.0 0.3 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 CHD5-like protein UPF0060 PF02694.15 AAG06663.1 - 4.3e-27 94.5 10.0 4.7e-27 94.3 10.0 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Peptidase_M48 PF01435.18 AAG06663.1 - 0.23 11.2 0.0 0.28 10.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M48 EamA PF00892.20 AAG06663.1 - 0.31 11.2 12.1 0.1 12.8 7.5 2.0 1 1 1 2 2 2 0 EamA-like transporter family Multi_Drug_Res PF00893.19 AAG06663.1 - 0.8 10.4 7.1 0.8 10.4 5.8 1.6 1 1 1 2 2 2 0 Small Multidrug Resistance protein TctB PF07331.11 AAG06663.1 - 1.3 9.3 12.1 2.2 8.6 12.1 1.5 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family adh_short PF00106.25 AAG06665.1 - 2.7e-49 167.3 0.0 4e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG06665.1 - 2.7e-43 148.2 0.0 3.4e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG06665.1 - 8.9e-09 35.5 0.1 1.5e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 KR domain TPPK_C PF12555.8 AAG06666.1 - 0.26 11.4 5.0 7.9 6.6 0.6 2.6 1 1 1 2 2 2 0 Thiamine pyrophosphokinase C terminal Porin_O_P PF07396.11 AAG06667.1 - 1.7e-108 363.0 15.8 2e-108 362.8 15.8 1.0 1 0 0 1 1 1 1 Phosphate-selective porin O and P Porin_O_P PF07396.11 AAG06668.1 - 6.9e-108 361.0 17.4 8e-108 360.8 17.4 1.0 1 0 0 1 1 1 1 Phosphate-selective porin O and P DoxX PF07681.12 AAG06669.1 - 1.2e-22 80.2 7.3 1.2e-22 80.2 7.3 1.8 2 0 0 2 2 2 1 DoxX DUF2063 PF09836.9 AAG06670.1 - 1.3e-27 95.9 0.2 2e-27 95.2 0.2 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain DUF3343 PF11823.8 AAG06670.1 - 0.0049 16.3 0.0 0.0087 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3343) DUF692 PF05114.13 AAG06671.1 - 2e-97 325.5 0.0 2.3e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) Sigma70_r2 PF04542.14 AAG06673.1 - 1.1e-12 47.5 0.4 2.2e-12 46.5 0.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAG06673.1 - 9.9e-12 44.3 3.2 5.1e-11 42.1 0.6 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG06673.1 - 1.6e-07 30.7 2.1 1.6e-07 30.7 2.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG06673.1 - 0.0086 16.0 2.6 0.065 13.1 2.6 2.0 1 1 0 1 1 1 1 ECF sigma factor HTH_20 PF12840.7 AAG06673.1 - 0.041 14.0 2.9 3.8 7.6 0.3 3.5 1 1 3 4 4 4 0 Helix-turn-helix domain ACP_syn_III_C PF08541.10 AAG06674.1 - 1.6e-22 79.5 0.2 6.8e-22 77.4 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAG06674.1 - 7.1e-18 64.2 0.4 1.5e-17 63.2 0.4 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AAG06674.1 - 7.2e-06 25.5 0.6 1.2e-05 24.9 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 AAG06674.1 - 0.00028 20.6 4.9 0.069 12.7 2.1 3.1 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.12 AAG06674.1 - 0.068 12.4 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Ribosomal_S9 PF00380.19 AAG06674.1 - 0.14 12.7 0.1 0.32 11.5 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Ank_2 PF12796.7 AAG06675.1 - 1.6e-21 76.7 2.5 2.2e-11 44.2 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AAG06675.1 - 4.1e-19 68.7 8.7 8.6e-08 32.6 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 AAG06675.1 - 3.5e-16 59.0 6.7 8.2e-08 32.4 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 AAG06675.1 - 7.5e-15 54.6 7.1 4.9e-05 23.6 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 AAG06675.1 - 5.9e-14 50.8 0.4 0.01 16.3 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Isochorismatase PF00857.20 AAG06676.1 - 2.3e-11 44.2 0.0 6.5e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family DUF2235 PF09994.9 AAG06678.1 - 6.3e-28 97.9 0.0 3.2e-16 59.5 0.0 2.5 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) TraD PF06412.11 AAG06678.1 - 0.023 14.5 1.3 0.094 12.5 0.3 2.6 3 0 0 3 3 3 0 Conjugal transfer protein TraD DUF3304 PF11745.8 AAG06679.1 - 6.5e-36 123.1 0.1 8.2e-36 122.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3304) DUF3304 PF11745.8 AAG06680.1 - 7.1e-57 190.6 0.6 1.6e-35 121.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3304) DUF4123 PF13503.6 AAG06681.1 - 1.7e-17 64.1 1.6 1.7e-17 64.1 1.6 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4123) DUF5356 PF17309.2 AAG06681.1 - 0.22 11.5 0.0 0.36 10.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5356) Phage_GPD PF05954.11 AAG06682.1 - 6e-79 265.5 1.0 6e-79 265.5 1.0 1.5 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 AAG06682.1 - 0.00019 21.4 0.2 0.0007 19.5 0.1 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) HIT PF01230.23 AAG06683.1 - 1.2e-26 93.3 0.0 1.5e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AAG06683.1 - 3e-13 50.2 0.0 3.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Alk_phosphatase PF00245.20 AAG06684.1 - 3.2e-127 425.0 0.1 4e-118 395.0 0.0 2.0 1 1 1 2 2 2 2 Alkaline phosphatase Metalloenzyme PF01676.18 AAG06684.1 - 5.4e-06 26.0 0.2 3.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF3418 PF11898.8 AAG06685.1 - 2.1e-201 670.6 13.6 3e-201 670.1 13.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) OB_NTP_bind PF07717.16 AAG06685.1 - 4.3e-22 78.3 0.0 8e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 AAG06685.1 - 5.2e-20 71.8 0.0 1.7e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AAG06685.1 - 9.8e-12 45.2 0.0 2.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AAG06685.1 - 0.00015 21.6 0.2 0.00038 20.3 0.2 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AAG06685.1 - 0.00026 21.3 0.1 0.0013 19.1 0.1 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAG06685.1 - 0.00047 20.5 0.1 0.001 19.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AAG06685.1 - 0.0008 18.5 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 AAG06685.1 - 0.0052 16.4 0.1 0.053 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAG06685.1 - 0.01 15.6 5.2 0.027 14.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AAG06685.1 - 0.02 14.8 3.8 0.026 14.4 0.4 3.0 3 1 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 AAG06685.1 - 0.039 14.5 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 AAG06685.1 - 0.054 14.0 0.2 0.14 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 AAG06685.1 - 0.078 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Unstab_antitox PF09720.10 AAG06686.1 - 0.0007 19.6 0.8 0.0017 18.3 0.5 1.9 1 1 0 1 1 1 1 Putative addiction module component AMP-binding PF00501.28 AAG06687.1 - 9.6e-107 357.2 0.1 1.2e-106 356.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG06687.1 - 1.5e-18 67.5 0.9 3.2e-17 63.3 0.1 2.9 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 AAG06687.1 - 0.02 15.2 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF599 PF04654.12 AAG06687.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 AMP-binding PF00501.28 AAG06688.1 - 5.3e-108 361.3 0.0 6.5e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG06688.1 - 2.4e-19 70.1 1.0 6.5e-19 68.7 0.4 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 AAG06688.1 - 0.0055 17.0 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hydrolase_4 PF12146.8 AAG06689.1 - 8.6e-69 231.4 0.1 1e-68 231.2 0.1 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG06689.1 - 6.7e-17 62.0 0.2 2.9e-16 59.9 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG06689.1 - 7.6e-16 59.4 4.4 1e-15 58.9 4.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAG06689.1 - 2.6e-06 27.1 0.0 7.3e-05 22.3 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 AAG06689.1 - 0.00028 20.5 0.0 0.0007 19.2 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 AAG06689.1 - 0.00037 20.7 0.9 0.0017 18.5 0.9 1.9 1 1 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 AAG06689.1 - 0.0013 18.3 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_4 PF08386.10 AAG06689.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF900 PF05990.12 AAG06689.1 - 0.059 12.9 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) EcoEI_R_C PF08463.10 AAG06689.1 - 0.063 13.4 0.0 0.32 11.1 0.0 2.1 3 0 0 3 3 3 0 EcoEI R protein C-terminal OKR_DC_1_N PF03709.15 AAG06689.1 - 0.16 12.3 0.0 2.4 8.5 0.0 2.5 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Abhydrolase_2 PF02230.16 AAG06689.1 - 0.18 11.6 0.0 7 6.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1749 PF08538.10 AAG06689.1 - 0.21 10.7 0.0 0.42 9.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) MaoC_dehydratas PF01575.19 AAG06690.1 - 1.9e-25 88.8 0.0 2.6e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAG06690.1 - 5.9e-08 32.9 0.0 8.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT_2 PF13279.6 AAG06690.1 - 0.0039 17.7 0.0 0.0045 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAG06690.1 - 0.025 15.0 0.0 0.053 13.9 0.0 1.6 1 1 0 1 1 1 0 Thioesterase superfamily MFS_1 PF07690.16 AAG06691.1 - 9e-45 153.1 82.9 7.5e-42 143.5 46.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG06691.1 - 1.6e-13 50.4 22.9 1.7e-12 46.9 10.6 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 AAG06691.1 - 9.4e-10 38.3 39.4 3.1e-09 36.6 39.4 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Biotin_lipoyl_2 PF13533.6 AAG06692.1 - 2.8e-16 59.1 12.0 1.2e-15 57.1 2.6 4.0 4 0 0 4 4 4 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAG06692.1 - 3.9e-16 59.7 2.6 2.1e-12 47.7 0.1 2.7 2 2 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAG06692.1 - 7.6e-14 51.4 6.8 2.4e-13 49.8 6.6 1.9 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAG06692.1 - 1.2e-06 28.3 0.8 2.5e-06 27.3 0.8 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG06692.1 - 0.00024 20.8 0.1 0.03 14.1 0.2 2.8 3 0 0 3 3 3 1 Biotin-requiring enzyme HlyD_2 PF12700.7 AAG06692.1 - 0.00063 18.6 0.0 0.0012 17.7 0.0 1.4 2 0 0 2 2 2 1 HlyD family secretion protein DUF1635 PF07795.11 AAG06692.1 - 0.013 15.4 0.7 0.017 15.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PmrD PF11183.8 AAG06692.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD FUSC PF04632.12 AAG06693.1 - 1.3e-197 658.4 48.9 1.4e-197 658.3 48.9 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAG06693.1 - 1.6e-11 44.4 12.9 1.6e-11 44.4 12.9 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 AAG06693.1 - 4.8e-05 22.4 3.0 9.5e-05 21.4 3.0 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter SUKH-4 PF14435.6 AAG06693.1 - 0.0019 18.3 0.3 0.0051 16.9 0.3 1.8 1 0 0 1 1 1 1 SUKH-4 immunity protein ArAE_1 PF06081.11 AAG06693.1 - 0.0032 17.6 8.0 0.0032 17.6 8.0 2.7 2 1 0 2 2 2 1 Aromatic acid exporter family member 1 2OG-FeII_Oxy_2 PF13532.6 AAG06694.1 - 1.2e-35 123.5 0.1 1.4e-35 123.3 0.1 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3682 PF12446.8 AAG06695.1 - 6.9 7.2 12.9 7.9 7.0 11.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) RapA_C PF12137.8 AAG06696.1 - 2.4e-139 464.3 0.1 3.9e-139 463.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal Tudor_RapA PF18337.1 AAG06696.1 - 2.3e-23 82.1 0.4 6.8e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 RapA N-terminal Tudor like domain Tudor_1_RapA PF18339.1 AAG06696.1 - 7.2e-23 80.3 0.0 1.5e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 RapA N-terminal Tudor like domain 1 SNF2_N PF00176.23 AAG06696.1 - 1.9e-14 53.2 0.0 2.9e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AAG06696.1 - 1.1e-13 51.5 0.0 3e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAG06696.1 - 2e-09 37.7 0.0 3.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AAG06696.1 - 0.00017 21.4 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Usp PF00582.26 AAG06697.1 - 1.8e-32 112.8 2.5 2.4e-32 112.4 2.5 1.2 1 0 0 1 1 1 1 Universal stress protein family Sulfatase PF00884.23 AAG06698.1 - 2.3e-54 184.9 0.0 2.8e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase EptA_B_N PF08019.12 AAG06698.1 - 6.7e-49 165.7 4.1 6.7e-49 165.7 4.1 1.7 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB Phosphodiest PF01663.22 AAG06698.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Rab5ip PF07019.12 AAG06698.1 - 0.34 11.5 5.1 0.15 12.7 2.1 2.1 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) EAL PF00563.20 AAG06699.1 - 3.1e-75 252.7 1.1 5.5e-75 251.9 1.1 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG06699.1 - 9.2e-47 158.8 0.2 1.8e-46 157.8 0.2 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MHYT PF03707.16 AAG06699.1 - 1.4e-39 134.1 27.5 1.3e-15 57.2 4.7 4.4 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat DUF3290 PF11694.8 AAG06699.1 - 0.012 15.6 0.7 0.078 12.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Guanylate_cyc PF00211.20 AAG06699.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain DUF717 PF05338.12 AAG06699.1 - 5.3 7.3 6.5 4.1 7.6 0.1 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF717) NAD_binding_2 PF03446.15 AAG06700.1 - 1.3e-46 158.6 0.0 2e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAG06700.1 - 8.3e-26 90.6 0.2 8.3e-26 90.6 0.2 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AAG06700.1 - 4.4e-05 24.0 0.1 0.00029 21.4 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent MR_MLE_C PF13378.6 AAG06700.1 - 0.0034 17.0 1.1 0.03 13.9 1.0 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like 2-Hacid_dh_C PF02826.19 AAG06700.1 - 0.0048 16.3 0.1 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phosphonate-bd PF12974.7 AAG06701.1 - 2.3e-68 230.4 0.5 2.8e-68 230.1 0.5 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAG06701.1 - 8.6e-14 51.5 0.1 1.3e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAG06701.1 - 2.8e-09 37.2 0.1 4e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 AAG06701.1 - 0.015 14.7 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 NMT1-like family DUF3086 PF11285.8 AAG06701.1 - 0.04 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) ABC_tran PF00005.27 AAG06702.1 - 1.6e-27 96.7 0.0 2.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAG06702.1 - 1.8e-05 25.2 1.0 3.6e-05 24.2 0.8 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAG06702.1 - 3.9e-05 23.5 0.2 6.3e-05 22.8 0.1 1.6 1 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAG06702.1 - 0.00027 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 AAG06702.1 - 0.0008 19.3 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 AAG06702.1 - 0.0015 18.5 0.1 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 AAG06702.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAG06702.1 - 0.016 14.8 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG06702.1 - 0.028 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AAG06702.1 - 0.038 14.0 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AAG06702.1 - 0.047 14.1 0.0 0.075 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAG06702.1 - 0.069 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AAG06702.1 - 0.08 13.1 0.2 0.48 10.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAG06702.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 AAG06702.1 - 0.15 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 AAG06702.1 - 0.15 11.7 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 AAG06702.1 - 0.2 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 AAG06702.1 - 0.26 11.0 0.0 0.41 10.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation BPD_transp_1 PF00528.22 AAG06703.1 - 4.6e-12 46.1 8.9 4.6e-12 46.1 8.9 2.0 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG06704.1 - 6.5e-12 45.6 10.9 6.5e-12 45.6 10.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4112 PF13430.6 AAG06704.1 - 0.065 13.5 1.6 5.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Phosphoesterase PF04185.14 AAG06707.1 - 2.2e-133 444.9 0.4 2.7e-133 444.6 0.4 1.1 1 0 0 1 1 1 1 Phosphoesterase family DUF756 PF05506.12 AAG06707.1 - 2.2e-41 140.6 2.4 6.3e-20 71.9 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF756) Cu-oxidase_2 PF07731.14 AAG06707.1 - 0.075 12.8 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Multicopper oxidase UCR_Fe-S_N PF10399.9 AAG06707.1 - 0.13 11.6 0.2 0.3 10.5 0.2 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 AAG06707.1 - 0.18 11.7 1.0 0.43 10.5 1.0 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DMT_YdcZ PF04657.13 AAG06708.1 - 4.7e-36 124.1 20.7 5.3e-36 123.9 20.7 1.0 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ DUF3493 PF11998.8 AAG06708.1 - 6 7.1 7.3 0.62 10.3 0.7 2.2 2 1 0 2 2 2 0 Low psii accumulation1 / Rep27 LysR_substrate PF03466.20 AAG06709.1 - 2.8e-23 82.4 12.3 4.9e-23 81.6 12.3 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06709.1 - 1.3e-17 63.4 1.5 4.3e-17 61.8 1.5 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG06709.1 - 0.0035 17.1 0.4 0.0095 15.7 0.4 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 AAG06709.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MerR_1 PF13411.6 AAG06710.1 - 7.2e-13 48.4 0.1 1.3e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAG06710.1 - 0.0046 16.7 0.6 0.012 15.3 0.6 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 AAG06710.1 - 0.02 15.4 3.2 0.042 14.4 0.3 2.7 3 0 0 3 3 3 0 MerR, DNA binding Peptidase_M24 PF00557.24 AAG06711.1 - 6.8e-25 88.0 0.0 8.2e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 adh_short PF00106.25 AAG06712.1 - 3e-47 160.6 0.0 4.3e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG06712.1 - 1.7e-37 129.3 0.1 2.4e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_1 PF00561.20 AAG06712.1 - 2.1e-17 63.6 0.2 7.4e-17 61.8 0.0 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG06712.1 - 3.2e-13 50.8 12.8 3.2e-13 50.8 12.8 2.2 2 1 1 3 3 3 1 Alpha/beta hydrolase family KR PF08659.10 AAG06712.1 - 2.8e-08 33.9 0.1 4.7e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Hydrolase_4 PF12146.8 AAG06712.1 - 9.7e-08 31.6 0.0 1.7e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Epimerase PF01370.21 AAG06712.1 - 0.12 11.8 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Metal_hydrol PF10118.9 AAG06713.1 - 7e-73 245.4 0.1 8.2e-73 245.2 0.1 1.0 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase PMT_2 PF13231.6 AAG06713.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase CLP_protease PF00574.23 AAG06714.1 - 4.3e-64 215.7 0.0 5e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 AAG06714.1 - 0.076 12.0 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase TetR_C_32 PF09209.11 AAG06714.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AMP-binding PF00501.28 AAG06715.1 - 6e-184 611.5 0.0 1.9e-101 339.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 AAG06715.1 - 2.1e-98 330.0 0.0 4e-55 187.3 0.0 2.1 2 0 0 2 2 2 2 Condensation domain Thioesterase PF00975.20 AAG06715.1 - 1.2e-32 113.9 0.0 3.3e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 AAG06715.1 - 1.2e-27 96.0 0.3 2.4e-12 47.0 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAG06715.1 - 2.7e-18 66.7 0.0 3e-09 37.7 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Abhydrolase_1 PF00561.20 AAG06715.1 - 0.00017 21.4 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06715.1 - 0.038 13.2 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 AAG06716.1 - 3.8e-25 88.9 0.1 5.3e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAG06716.1 - 1e-05 25.6 1.5 3.1e-05 24.1 1.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 AAG06716.1 - 1.8e-05 24.2 0.7 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 AAG06716.1 - 7.2e-05 22.2 0.2 0.0005 19.4 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AAG06716.1 - 0.0002 20.3 1.4 0.15 10.9 0.2 2.8 2 1 0 3 3 3 2 Tryptophan halogenase Bac_globin PF01152.21 AAG06716.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Bacterial-like globin DAO PF01266.24 AAG06716.1 - 0.0055 16.3 7.4 0.084 12.4 1.8 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAG06716.1 - 0.012 14.9 0.1 0.027 13.8 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 AAG06716.1 - 0.034 13.8 0.3 0.066 12.9 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 AAG06716.1 - 0.068 12.2 2.1 0.48 9.4 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 AAG06716.1 - 0.12 12.9 0.2 0.12 12.9 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG06716.1 - 0.13 11.4 1.4 0.19 10.8 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 AAG06716.1 - 0.22 10.2 1.5 0.35 9.5 0.9 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 AAG06716.1 - 0.23 10.5 8.9 2.2 7.2 8.9 2.4 1 1 0 1 1 1 0 FAD binding domain Condensation PF00668.20 AAG06717.1 - 3.2e-17 62.4 0.0 2.5e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.16 AAG06717.1 - 0.0098 15.7 1.5 0.14 11.9 0.2 2.6 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 AAG06717.1 - 0.075 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Transferase family adh_short PF00106.25 AAG06718.1 - 4.5e-44 150.3 0.0 5.8e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG06718.1 - 3.4e-32 111.9 0.0 5.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG06718.1 - 9.2e-10 38.7 0.1 1.7e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AAG06718.1 - 0.00017 21.1 0.0 0.00036 20.0 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 AAG06718.1 - 0.00027 20.9 0.6 0.00027 20.9 0.6 2.3 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 AAG06718.1 - 0.014 14.9 0.3 0.053 13.0 0.1 2.0 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 AAG06718.1 - 0.028 15.4 1.6 0.26 12.3 0.1 2.7 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator NmrA PF05368.13 AAG06718.1 - 0.16 11.5 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.22 AAG06719.1 - 2.3e-23 82.7 0.0 1e-17 64.1 0.0 3.1 1 1 0 1 1 1 1 Cytochrome P450 DUF2523 PF10734.9 AAG06719.1 - 0.088 13.4 0.7 0.17 12.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) SnoaL_2 PF12680.7 AAG06720.1 - 4.8e-12 46.4 0.1 6e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain PHZA_PHZB PF03284.13 AAG06720.1 - 8.1e-08 32.0 0.0 9.3e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B DUF4440 PF14534.6 AAG06720.1 - 0.024 15.0 0.0 0.034 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 AAG06720.1 - 0.045 13.9 0.0 0.068 13.3 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.20 AAG06720.1 - 0.07 13.7 0.0 0.083 13.5 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain ACP_syn_III_C PF08541.10 AAG06721.1 - 1e-32 112.1 0.2 2.9e-32 110.7 0.2 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAG06721.1 - 5.3e-25 87.1 1.8 1.2e-24 86.0 1.8 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AAG06721.1 - 0.0082 15.5 0.1 0.017 14.5 0.1 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 AAG06722.1 - 1.1e-07 32.1 1.7 1.2e-07 32.0 1.7 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 AAG06723.1 - 0.00017 22.3 0.0 0.00035 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG06723.1 - 0.0043 17.7 0.0 0.0076 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG06723.1 - 0.005 17.5 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG06723.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 AAG06723.1 - 0.012 14.8 0.0 0.051 12.7 0.0 1.8 1 1 1 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_31 PF13847.6 AAG06723.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 AAG06724.1 - 3.8e-36 124.8 73.7 9e-36 123.5 56.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAG06724.1 - 0.0028 16.3 1.7 0.0028 16.3 1.7 3.3 1 1 2 3 3 3 2 MFS/sugar transport protein DUF1211 PF06736.11 AAG06724.1 - 0.22 12.0 3.2 0.27 11.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) MFS_4 PF06779.14 AAG06724.1 - 0.47 9.7 55.8 0.57 9.4 55.8 1.0 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Epimerase PF01370.21 AAG06725.1 - 2.5e-41 141.7 0.0 3.1e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAG06725.1 - 5.7e-15 55.6 0.0 1.7e-14 54.0 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAG06725.1 - 1.7e-10 40.5 0.0 5.2e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAG06725.1 - 2.2e-09 36.7 0.0 3.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAG06725.1 - 0.00025 20.3 0.0 0.71 8.9 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAG06725.1 - 0.012 14.8 0.0 0.88 8.7 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein Ldh_1_N PF00056.23 AAG06725.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF1707 PF08044.11 AAG06725.1 - 0.19 11.8 1.4 0.39 10.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) DapB_N PF01113.20 AAG06725.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rdx PF10262.9 AAG06726.1 - 1.7e-32 111.4 0.0 1.9e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Rdx family Patatin PF01734.22 AAG06727.1 - 1.7e-28 100.2 1.7 8.7e-28 97.9 1.7 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Bac_surface_Ag PF01103.23 AAG06727.1 - 2.1e-09 37.3 5.8 2.1e-09 37.3 5.8 2.1 1 1 0 1 1 1 1 Surface antigen POTRA PF07244.15 AAG06727.1 - 4.4e-06 27.2 0.1 1.7e-05 25.3 0.1 2.1 1 0 0 1 1 1 1 Surface antigen variable number repeat ATG16 PF08614.11 AAG06728.1 - 0.0012 19.2 8.9 0.0021 18.3 8.9 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 AAG06728.1 - 0.0029 17.0 13.2 0.005 16.2 13.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) FTA4 PF13093.6 AAG06728.1 - 0.0035 17.2 0.9 0.0078 16.1 0.9 1.5 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HOOK PF05622.12 AAG06728.1 - 0.0045 15.2 1.8 0.0062 14.8 1.8 1.1 1 0 0 1 1 1 1 HOOK protein DUF1664 PF07889.12 AAG06728.1 - 0.0046 17.0 2.9 0.0076 16.3 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) TPR_14 PF13428.6 AAG06728.1 - 0.0068 17.1 7.1 0.032 15.0 0.8 5.1 3 2 1 4 4 2 2 Tetratricopeptide repeat Golgin_A5 PF09787.9 AAG06728.1 - 0.012 15.1 7.1 0.018 14.5 7.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 AAG06728.1 - 0.012 14.9 2.3 0.023 14.1 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HemX PF04375.14 AAG06728.1 - 0.012 14.9 9.7 0.024 14.0 9.7 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Macoilin PF09726.9 AAG06728.1 - 0.018 13.6 0.2 0.025 13.2 0.2 1.1 1 0 0 1 1 1 0 Macoilin family TPR_2 PF07719.17 AAG06728.1 - 0.018 15.1 0.3 0.76 10.0 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF812 PF05667.11 AAG06728.1 - 0.024 13.6 1.4 0.033 13.1 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF641 PF04859.12 AAG06728.1 - 0.025 14.9 4.8 0.045 14.1 4.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) GAS PF13851.6 AAG06728.1 - 0.033 13.5 8.4 0.051 12.9 8.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_19 PF14559.6 AAG06728.1 - 0.037 14.5 26.0 0.049 14.1 0.1 4.6 4 1 0 4 4 3 0 Tetratricopeptide repeat Mod_r PF07200.13 AAG06728.1 - 0.039 14.0 4.3 0.069 13.3 4.3 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein KASH_CCD PF14662.6 AAG06728.1 - 0.04 13.8 5.5 0.067 13.0 5.5 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 AAG06728.1 - 0.05 13.8 0.2 0.083 13.1 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Phage_GPO PF05929.11 AAG06728.1 - 0.051 13.2 3.5 0.11 12.1 3.5 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TMF_TATA_bd PF12325.8 AAG06728.1 - 0.063 13.5 5.8 0.15 12.3 5.6 1.6 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding TPR_6 PF13174.6 AAG06728.1 - 0.076 13.7 0.8 4.9 8.0 0.4 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Cluap1 PF10234.9 AAG06728.1 - 0.08 12.3 6.9 0.12 11.8 6.9 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 FAM76 PF16046.5 AAG06728.1 - 0.082 12.3 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein TPR_4 PF07721.14 AAG06728.1 - 0.083 13.6 0.2 0.083 13.6 0.2 6.1 8 0 0 8 8 2 0 Tetratricopeptide repeat BatD PF13584.6 AAG06728.1 - 0.09 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance APG6_N PF17675.1 AAG06728.1 - 0.099 13.2 10.6 0.18 12.3 10.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 AAG06728.1 - 0.1 12.9 1.4 0.19 12.0 1.4 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Taxilin PF09728.9 AAG06728.1 - 0.11 11.6 7.4 0.16 11.1 7.4 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Spc7 PF08317.11 AAG06728.1 - 0.12 11.2 6.5 0.18 10.6 6.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 AAG06728.1 - 0.12 11.4 6.1 0.19 10.8 6.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 AAG06728.1 - 0.21 11.2 7.2 0.33 10.5 7.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Sec2p PF06428.11 AAG06728.1 - 0.26 11.3 6.8 0.51 10.3 6.8 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cnn_1N PF07989.11 AAG06728.1 - 0.3 11.3 6.5 0.64 10.2 6.5 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Prefoldin PF02996.17 AAG06728.1 - 0.3 11.0 6.0 1.2 9.1 6.3 1.8 2 0 0 2 2 1 0 Prefoldin subunit DUF2968 PF11180.8 AAG06728.1 - 0.34 10.5 17.6 0.055 13.1 13.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) 60KD_IMP PF02096.20 AAG06728.1 - 0.34 10.8 1.3 1 9.2 1.7 1.5 2 0 0 2 2 1 0 60Kd inner membrane protein IFT57 PF10498.9 AAG06728.1 - 0.37 9.7 4.1 0.52 9.2 4.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF724 PF05266.14 AAG06728.1 - 0.37 10.6 3.4 0.58 10.0 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GPL PF05926.11 AAG06728.1 - 0.4 10.7 4.3 0.77 9.8 4.3 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) MPS2 PF17060.5 AAG06728.1 - 0.59 9.3 1.4 0.83 8.9 1.4 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 ERM PF00769.19 AAG06728.1 - 0.65 9.8 10.7 1.1 9.1 10.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mitofilin PF09731.9 AAG06728.1 - 0.7 8.7 12.2 3 6.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein FliD_C PF07195.12 AAG06728.1 - 0.79 9.1 1.7 1.2 8.5 1.7 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TPD52 PF04201.15 AAG06728.1 - 0.98 9.0 2.7 1.6 8.4 2.7 1.2 1 0 0 1 1 1 0 Tumour protein D52 family TMPIT PF07851.13 AAG06728.1 - 0.99 8.6 2.8 1.5 8.0 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein ADIP PF11559.8 AAG06728.1 - 1 9.4 10.7 1.7 8.7 10.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 AAG06728.1 - 1.1 9.3 15.0 2.2 8.3 15.0 1.4 1 0 0 1 1 1 0 FlxA-like protein Cytochrom_B562 PF07361.11 AAG06728.1 - 1.3 9.8 6.2 24 5.7 4.3 2.5 2 0 0 2 2 2 0 Cytochrome b562 UPF0242 PF06785.11 AAG06728.1 - 1.4 9.0 5.9 2.3 8.3 5.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 AAG06728.1 - 1.4 9.2 9.9 4.6 7.6 9.9 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain AAA_13 PF13166.6 AAG06728.1 - 1.9 7.0 5.1 2.6 6.6 5.1 1.1 1 0 0 1 1 1 0 AAA domain VPDSG-CTERM PF18205.1 AAG06728.1 - 4.6 7.2 10.4 8.8 6.3 10.4 1.5 1 0 0 1 1 1 0 VPDSG-CTERM motif DotU PF09850.9 AAG06728.1 - 4.7 6.9 11.0 1.8 8.2 6.2 2.5 2 1 0 2 2 2 0 Type VI secretion system protein DotU OmpH PF03938.14 AAG06728.1 - 7.8 6.8 14.3 14 6.0 14.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 AAG06728.1 - 9.3 7.0 16.7 1.8 9.2 11.8 2.5 2 0 0 2 2 1 0 SlyX MarR_2 PF12802.7 AAG06729.1 - 1.7e-11 43.8 3.8 1.7e-11 43.8 3.8 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AAG06729.1 - 2.4e-11 43.4 0.6 4.2e-11 42.6 0.1 1.7 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAG06729.1 - 1.3e-08 35.2 0.2 2.1e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAG06729.1 - 3.9e-06 26.6 2.1 9.7e-06 25.3 2.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 AAG06729.1 - 0.0001 22.6 0.0 0.00054 20.3 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AAG06729.1 - 0.00016 21.5 0.5 0.00036 20.5 0.5 1.8 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 AAG06729.1 - 0.00018 21.1 1.2 0.0017 17.9 0.3 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 AAG06729.1 - 0.00029 20.6 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 AAG06729.1 - 0.00098 19.2 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 AAG06729.1 - 0.0016 18.0 0.0 0.0036 16.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 AAG06729.1 - 0.0091 16.3 0.9 0.0091 16.3 0.9 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_36 PF13730.6 AAG06729.1 - 0.037 14.0 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AAG06729.1 - 0.043 13.6 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Fe_dep_repress PF01325.19 AAG06729.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF2804 PF10974.8 AAG06730.1 - 3.1e-81 273.5 0.0 3.5e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) GGDEF PF00990.21 AAG06731.1 - 4.4e-49 166.3 0.2 5.7e-49 166.0 0.2 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF2207 PF09972.9 AAG06731.1 - 0.48 9.1 1.3 0.49 9.1 0.1 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) RQC PF09382.10 AAG06732.1 - 4.3e-36 123.2 0.0 8.7e-36 122.2 0.0 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 AAG06732.1 - 7.1e-23 80.4 0.1 1.9e-22 79.0 0.1 1.8 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 AAG06732.1 - 1.2e-20 74.0 3.9 1.2e-20 74.0 3.9 1.9 2 0 0 2 2 1 1 RecQ zinc-binding Helicase_C PF00271.31 AAG06732.1 - 6.8e-20 71.5 0.0 6.3e-16 58.7 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 AAG06732.1 - 2.7e-19 69.6 0.0 4.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HTH_38 PF13936.6 AAG06732.1 - 0.00011 21.9 0.0 0.0023 17.7 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_40 PF14493.6 AAG06732.1 - 0.00013 22.3 0.0 0.00043 20.7 0.0 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAG06732.1 - 0.001 18.7 0.0 0.0053 16.4 0.0 2.3 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 AAG06732.1 - 0.0023 17.5 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_29 PF13551.6 AAG06732.1 - 0.0098 15.9 0.1 0.12 12.4 0.0 2.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAG06732.1 - 0.01 15.6 1.8 0.066 13.0 0.0 3.2 4 0 0 4 4 4 0 Homeodomain-like domain Transposase_mut PF00872.18 AAG06732.1 - 0.022 13.6 0.1 0.037 12.9 0.1 1.2 1 0 0 1 1 1 0 Transposase, Mutator family IF2_N PF04760.15 AAG06732.1 - 0.14 12.0 0.0 36 4.3 0.0 2.9 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Hpt PF01627.23 AAG06733.1 - 9e-15 54.7 2.1 1.4e-14 54.1 2.1 1.3 1 0 0 1 1 1 1 Hpt domain SpoIIE PF07228.12 AAG06734.1 - 2.3e-39 135.3 0.0 4e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AAG06734.1 - 1e-24 86.8 0.0 1.9e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAG06734.1 - 8e-10 38.7 0.0 2.3e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 AAG06734.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase STAS_2 PF13466.6 AAG06735.1 - 1.5e-14 54.1 0.0 1.8e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAG06735.1 - 7.3e-10 38.5 0.0 8.5e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 STAS domain CheR PF01739.18 AAG06736.1 - 1.1e-67 227.3 0.0 1.7e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAG06736.1 - 1.4e-13 50.3 0.0 2.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 AAG06736.1 - 3.1e-07 31.0 0.0 3.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG06736.1 - 1.8e-06 28.5 0.0 5.5e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG06736.1 - 4.4e-06 27.3 0.0 0.0002 22.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG06736.1 - 0.00016 21.5 0.0 0.00048 19.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG06736.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_29 PF03141.16 AAG06736.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CheW PF01584.19 AAG06737.1 - 2.1e-34 118.1 0.2 3.5e-34 117.4 0.2 1.4 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AAG06737.1 - 5.3e-17 62.0 0.2 9.2e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain ChapFlgA PF13144.6 AAG06738.1 - 1.1e-38 132.1 3.7 1.5e-38 131.6 3.7 1.2 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation ChapFlgA_N PF17656.1 AAG06738.1 - 7.2e-23 80.5 0.1 3.1e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 FlgA N-terminal domain SAF PF08666.12 AAG06738.1 - 1.4e-09 38.4 2.0 7.6e-08 32.9 0.4 3.1 3 0 0 3 3 3 1 SAF domain FlgM PF04316.13 AAG06739.1 - 1.4e-20 73.4 1.5 1.4e-20 73.4 1.5 1.5 2 0 0 2 2 2 1 Anti-sigma-28 factor, FlgM Adhesin_P1 PF03257.13 AAG06739.1 - 0.21 12.1 5.6 0.47 11.0 5.2 1.8 1 1 0 1 1 1 0 Mycoplasma adhesin P1 FlgN PF05130.12 AAG06740.1 - 1.5e-31 109.9 1.8 1.7e-31 109.7 1.8 1.0 1 0 0 1 1 1 1 FlgN protein YcgR PF07317.12 AAG06741.1 - 3.6e-26 91.1 0.0 1.1e-25 89.5 0.0 1.7 2 0 0 2 2 2 1 Flagellar regulator YcgR PilZ PF07238.14 AAG06741.1 - 9.6e-09 35.5 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 PilZ domain YcgR_2 PF12945.7 AAG06741.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein YcgR DICT PF10069.9 AAG06741.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF2064 PF09837.9 AAG06742.1 - 2.6e-29 101.6 0.1 3.5e-29 101.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) NTP_transf_3 PF12804.7 AAG06742.1 - 0.003 18.0 1.3 0.016 15.6 1.3 2.0 1 1 0 1 1 1 1 MobA-like NTP transferase domain MFS_1 PF07690.16 AAG06743.1 - 7.7e-31 107.3 53.2 9.6e-17 60.9 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG06743.1 - 2.4e-05 23.4 25.7 0.00045 19.2 10.9 3.8 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAG06743.1 - 0.00023 20.1 6.0 0.00023 20.1 6.0 2.2 1 1 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 AAG06743.1 - 0.00038 19.0 4.9 0.00038 19.0 4.9 3.1 2 1 1 3 3 3 2 Transmembrane secretion effector MFS_4 PF06779.14 AAG06743.1 - 0.0046 16.3 31.0 0.033 13.5 31.0 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AAG06743.1 - 1.6 6.9 9.0 7.9 4.6 0.1 3.6 2 2 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Gln-synt_C PF00120.24 AAG06744.1 - 5e-103 344.7 0.0 5.7e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain PALP PF00291.25 AAG06745.1 - 2.1e-57 194.8 0.2 2.8e-57 194.4 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SKI PF01202.22 AAG06745.1 - 0.19 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase EamA PF00892.20 AAG06746.1 - 1.4e-27 96.5 38.4 1.2e-15 57.9 16.9 2.0 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 AAG06746.1 - 0.00018 20.8 1.3 0.024 13.8 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TMEM234 PF10639.9 AAG06746.1 - 0.00055 20.0 0.2 0.43 10.6 0.0 2.4 2 0 0 2 2 2 2 Putative transmembrane family 234 UAA PF08449.11 AAG06746.1 - 0.064 12.4 3.8 0.075 12.2 0.6 2.1 2 0 0 2 2 2 0 UAA transporter family DUF2955 PF11168.8 AAG06747.1 - 4.5e-48 162.7 16.1 4.5e-48 162.7 16.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2955) FUSC_2 PF13515.6 AAG06747.1 - 5.1e-10 39.6 29.8 6.7e-10 39.2 10.4 2.7 1 1 1 2 2 2 2 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AAG06747.1 - 0.036 14.2 17.1 1.5 9.0 1.5 3.8 2 2 2 4 4 4 0 Aromatic acid exporter family member 1 DUF1148 PF06618.11 AAG06747.1 - 0.22 11.7 1.3 0.43 10.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1148) HlyD_D23 PF16576.5 AAG06748.1 - 2.5e-14 53.0 1.4 3.9e-12 45.9 1.4 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG06748.1 - 5.5e-13 48.5 0.0 5.5e-13 48.5 0.0 4.4 6 0 0 6 6 6 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAG06748.1 - 6.6e-12 46.1 1.1 2.3e-07 31.5 0.1 3.0 4 0 0 4 4 4 2 HlyD family secretion protein HlyD PF00529.20 AAG06748.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.3 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG06748.1 - 0.0019 18.0 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme RdRP_4 PF02123.16 AAG06748.1 - 0.034 13.0 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase GAS PF13851.6 AAG06748.1 - 0.51 9.6 5.9 1.1 8.5 5.6 1.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 AAG06748.1 - 0.78 9.8 4.4 0.58 10.2 0.6 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3494 PF11999.8 AAG06748.1 - 2.3 7.8 4.4 1.6 8.3 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3494) PA-IIL PF07472.11 AAG06749.1 - 3.6e-46 155.9 2.2 4e-46 155.7 2.2 1.0 1 0 0 1 1 1 1 Fucose-binding lectin II (PA-IIL) DUF4114 PF13448.6 AAG06749.1 - 0.00015 22.5 5.0 0.00046 20.9 5.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4114) Triabin PF03973.13 AAG06749.1 - 0.05 13.5 0.5 0.064 13.1 0.5 1.1 1 0 0 1 1 1 0 Triabin AmiS_UreI PF02293.15 AAG06750.1 - 2.1e-56 190.5 23.7 2.3e-56 190.4 23.7 1.0 1 0 0 1 1 1 1 AmiS/UreI family transporter ANTAR PF03861.14 AAG06751.1 - 3.6e-14 52.3 4.0 3.6e-14 52.3 4.0 1.9 2 0 0 2 2 2 1 ANTAR domain 60KD_IMP PF02096.20 AAG06751.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein Uds1 PF15456.6 AAG06751.1 - 0.13 12.4 3.4 0.18 11.9 3.4 1.2 1 0 0 1 1 1 0 Up-regulated During Septation CALM_bind PF16025.5 AAG06751.1 - 0.14 12.6 2.8 0.21 12.0 2.8 1.3 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Peripla_BP_5 PF13433.6 AAG06752.1 - 1.4e-114 382.9 0.0 1.6e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AAG06752.1 - 6e-67 226.7 0.1 7.4e-67 226.4 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Glyco_tran_WecB PF03808.13 AAG06752.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family AAA_2 PF07724.14 AAG06753.1 - 1.3e-39 136.1 0.0 1.9e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 AAG06753.1 - 2.5e-18 65.9 0.1 5.1e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AAG06753.1 - 7.4e-11 42.2 0.0 2.9e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAG06753.1 - 8.7e-09 35.9 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AAG06753.1 - 2.3e-08 33.9 0.0 3.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 AAG06753.1 - 4.8e-06 27.1 0.3 6.1e-05 23.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 AAG06753.1 - 0.0009 19.4 0.0 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AAG06753.1 - 0.00096 19.0 0.0 0.013 15.4 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AAG06753.1 - 0.0033 17.9 0.0 0.0065 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAG06753.1 - 0.0053 16.2 0.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AAG06753.1 - 0.01 15.6 0.6 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAG06753.1 - 0.01 16.4 0.3 0.031 14.8 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.6 AAG06753.1 - 0.017 15.4 0.0 0.15 12.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAG06753.1 - 0.032 14.6 0.0 0.16 12.4 0.0 2.1 1 1 0 1 1 1 0 RNA helicase Ric8 PF10165.9 AAG06753.1 - 0.075 12.1 0.0 0.17 10.9 0.0 1.5 1 1 1 2 2 2 0 Guanine nucleotide exchange factor synembryn AAA_7 PF12775.7 AAG06753.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 AAG06753.1 - 0.091 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter THDPS_N_2 PF14805.6 AAG06753.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal AAA_6 PF12774.7 AAG06753.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region CN_hydrolase PF00795.22 AAG06754.1 - 4e-54 183.7 0.2 5e-54 183.4 0.2 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FUSC_2 PF13515.6 AAG06755.1 - 0.2 11.8 0.1 0.2 11.8 0.1 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Acetyltransf_1 PF00583.25 AAG06756.1 - 4.6e-17 62.3 0.0 6.5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG06756.1 - 4.9e-11 42.9 0.0 7.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG06756.1 - 1.3e-10 41.3 0.0 2.6e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAG06756.1 - 2.2e-05 24.2 0.1 3.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 AAG06756.1 - 0.00085 19.5 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG06756.1 - 0.0028 17.8 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAG06756.1 - 0.037 14.1 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG06756.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF4191 PF13829.6 AAG06759.1 - 0.7 9.2 2.0 0.82 9.0 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Lactamase_B_2 PF12706.7 AAG06760.1 - 5.5e-17 61.9 0.0 8.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAG06760.1 - 1.1e-05 25.6 0.9 5.7e-05 23.2 0.5 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 AAG06760.1 - 0.03 14.2 0.0 0.09 12.7 0.0 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain AAA_18 PF13238.6 AAG06761.1 - 7e-06 26.6 0.0 1.7e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAG06761.1 - 3.8e-05 23.9 0.0 0.00016 21.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG06761.1 - 0.0012 19.2 1.4 0.0073 16.7 1.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain Guanylate_kin PF00625.21 AAG06761.1 - 0.005 16.5 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase Ploopntkinase3 PF18751.1 AAG06761.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 AAG06761.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AAG06761.1 - 0.21 12.1 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.11 AAG06761.1 - 0.3 10.0 0.0 0.41 9.5 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Amidohydro_3 PF07969.11 AAG06762.1 - 2.5e-10 40.4 9.5 3.8e-07 30.0 3.9 3.1 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 AAG06762.1 - 0.00053 19.4 0.5 0.0024 17.2 0.5 2.2 1 1 0 1 1 1 1 Amidohydrolase family ABC_tran PF00005.27 AAG06763.1 - 3.8e-26 92.2 0.0 5.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAG06763.1 - 3.7e-05 24.2 0.3 6.2e-05 23.4 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG06763.1 - 0.00032 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAG06763.1 - 0.00092 19.5 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAG06763.1 - 0.001 18.5 0.0 0.012 15.1 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAG06763.1 - 0.0021 17.9 0.2 0.57 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAG06763.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAG06763.1 - 0.013 15.3 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAG06763.1 - 0.014 15.2 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 AAG06763.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 AAG06763.1 - 0.055 13.7 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 AAG06763.1 - 0.055 13.6 0.5 0.19 11.9 0.1 2.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 AAG06763.1 - 0.069 13.1 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 AAG06763.1 - 0.15 12.1 0.1 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 AAG06763.1 - 0.27 11.7 0.0 0.41 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAG06764.1 - 2e-27 96.4 0.0 2.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06764.1 - 1.1e-08 35.3 0.0 0.00015 21.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AAG06764.1 - 7.2e-06 26.4 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_29 PF13555.6 AAG06764.1 - 0.0018 18.0 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG06764.1 - 0.0043 17.0 0.2 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AAG06764.1 - 0.0047 17.3 0.8 0.014 15.8 0.8 1.7 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 AAG06764.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 AAG06764.1 - 0.018 15.5 0.0 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 AAG06764.1 - 0.019 14.4 0.4 2 7.8 0.3 2.8 2 1 1 3 3 3 0 Bacterial TniB protein AAA_22 PF13401.6 AAG06764.1 - 0.038 14.3 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAG06764.1 - 0.039 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AAG06764.1 - 0.097 12.8 0.0 0.29 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG06764.1 - 0.12 12.0 0.0 3.7 7.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 AAG06764.1 - 0.13 11.8 1.1 1.5 8.4 1.1 2.3 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAG06764.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain PhnJ PF06007.11 AAG06765.1 - 4.5e-145 481.8 0.0 5.4e-145 481.5 0.0 1.0 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnJ PhnI PF05861.12 AAG06766.1 - 1.9e-161 536.8 0.0 2.1e-161 536.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnI) PhnG PF06754.12 AAG06766.1 - 0.00024 21.1 0.0 0.0046 16.9 0.0 2.3 1 1 0 1 1 1 1 Phosphonate metabolism protein PhnG PhnH PF05845.12 AAG06767.1 - 1.2e-57 194.7 0.0 1.4e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnH) PhnG PF06754.12 AAG06768.1 - 1.8e-55 186.8 6.7 2.1e-55 186.6 6.7 1.0 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnG UTRA PF07702.13 AAG06769.1 - 4.4e-31 107.6 0.5 7.7e-31 106.8 0.5 1.4 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAG06769.1 - 1.2e-17 63.3 1.3 2.9e-17 62.0 1.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AAG06769.1 - 0.091 12.7 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_DeoR PF08220.12 AAG06769.1 - 0.093 12.5 0.5 0.41 10.4 0.3 2.0 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain BPD_transp_1 PF00528.22 AAG06770.1 - 7.6e-19 68.2 11.8 7.6e-19 68.2 11.8 1.6 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component LRRC37AB_C PF14914.6 AAG06770.1 - 0.57 10.1 1.7 14 5.6 1.6 2.4 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Phosphonate-bd PF12974.7 AAG06771.1 - 5.8e-71 238.9 0.1 7.2e-71 238.6 0.1 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein YukC PF10140.9 AAG06771.1 - 0.061 12.1 0.6 0.12 11.2 0.6 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ABC_tran PF00005.27 AAG06772.1 - 5.4e-33 114.4 0.0 7.2e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06772.1 - 8e-08 32.4 0.1 0.0015 18.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG06772.1 - 6.1e-05 23.5 3.5 0.00048 20.5 3.5 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG06772.1 - 0.0002 21.0 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 AAG06772.1 - 0.00066 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 AAG06772.1 - 0.00084 19.5 0.1 0.0042 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAG06772.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AAG06772.1 - 0.0028 17.1 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAG06772.1 - 0.0034 17.1 0.3 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAG06772.1 - 0.0039 17.5 0.2 0.035 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AAG06772.1 - 0.0069 16.5 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 AAG06772.1 - 0.012 15.3 0.1 0.025 14.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAG06772.1 - 0.013 15.7 0.1 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAG06772.1 - 0.016 14.8 1.0 0.052 13.1 1.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAG06772.1 - 0.036 14.6 0.0 0.21 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain HNHc_6 PF16784.5 AAG06772.1 - 0.042 13.4 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative HNHc nuclease AAA_5 PF07728.14 AAG06772.1 - 0.043 13.8 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 AAG06772.1 - 0.062 13.5 0.5 0.59 10.4 0.5 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 AAG06772.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG06772.1 - 0.2 11.3 0.0 3.1 7.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF4264 PF14084.6 AAG06772.1 - 0.22 11.2 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Arc PF03869.14 AAG06773.1 - 1.5e-28 98.3 0.5 1.5e-28 98.3 0.5 1.6 2 0 0 2 2 2 1 Arc-like DNA binding domain HicB PF05534.12 AAG06773.1 - 0.0078 16.0 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 HicB family DUF2784 PF10861.8 AAG06774.1 - 1.8e-40 137.4 2.2 2.1e-40 137.3 2.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF2784) AA_permease_C PF13906.6 AAG06774.1 - 0.19 11.9 4.7 1.8 8.7 0.8 2.6 2 0 0 2 2 2 0 C-terminus of AA_permease RAMP4 PF06624.12 AAG06774.1 - 7.7 6.7 4.8 14 5.9 4.8 1.3 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 adh_short_C2 PF13561.6 AAG06775.1 - 6e-55 186.3 0.3 7.1e-55 186.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06775.1 - 4.3e-46 156.8 0.0 5e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG06775.1 - 2.7e-08 33.9 0.5 6.8e-08 32.6 0.5 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 AAG06775.1 - 0.00088 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAG06775.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) FIST_C PF10442.9 AAG06775.1 - 0.012 15.6 1.6 0.034 14.1 1.6 1.8 1 1 0 1 1 1 0 FIST C domain THF_DHG_CYH_C PF02882.19 AAG06775.1 - 0.084 12.2 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrmO PF01980.16 AAG06776.1 - 2.2e-45 153.7 0.0 2.9e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 AAG06776.1 - 2.9e-22 78.5 0.2 4.4e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 TrmO C-terminal domain ABM PF03992.16 AAG06777.1 - 8.4e-20 70.7 0.0 1.1e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Glyoxalase PF00903.25 AAG06778.1 - 1.6e-19 70.3 0.0 2e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG06778.1 - 5.3e-05 24.0 0.0 7.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAG06778.1 - 0.0066 16.7 0.0 0.32 11.3 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AAG06778.1 - 0.0078 16.1 0.0 0.047 13.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain tRNA_U5-meth_tr PF05958.11 AAG06778.1 - 0.16 10.9 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Fer4_5 PF12801.7 AAG06779.1 - 9e-19 67.2 20.0 6.7e-15 54.8 2.3 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain FMN_bind PF04205.14 AAG06779.1 - 9e-07 29.4 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 FMN-binding domain PHF5 PF03660.14 AAG06779.1 - 0.021 15.0 2.7 0.041 14.1 2.7 1.4 1 0 0 1 1 1 0 PHF5-like protein GASA PF02704.14 AAG06779.1 - 0.88 9.8 8.0 1.5 9.0 8.0 1.3 1 0 0 1 1 1 0 Gibberellin regulated protein C1_1 PF00130.22 AAG06779.1 - 1.1 9.2 7.9 2.1 8.3 7.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) nos_propeller PF18764.1 AAG06780.1 - 6.1e-37 125.4 0.4 3.9e-34 116.4 0.0 3.0 3 0 0 3 3 3 2 Nitrous oxide reductase propeller repeat nos_propeller_2 PF18793.1 AAG06780.1 - 5.4e-34 116.4 0.8 1.1e-32 112.2 0.1 2.7 2 0 0 2 2 2 1 Nitrous oxide reductase propeller repeat 2 COX2 PF00116.20 AAG06780.1 - 3.9e-05 23.5 0.1 8.7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 AAG06780.1 - 5.5e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain TAT_signal PF10518.9 AAG06780.1 - 0.014 15.2 9.1 0.025 14.4 9.1 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Cu-oxidase_3 PF07732.15 AAG06780.1 - 0.021 14.8 0.1 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Multicopper oxidase NosD PF05048.13 AAG06781.1 - 2.7e-70 236.4 7.3 1.2e-68 231.0 9.2 1.9 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 AAG06781.1 - 1.6e-24 86.5 8.0 5.2e-17 62.2 0.2 2.4 1 1 1 2 2 2 2 Right handed beta helix region ABC_tran PF00005.27 AAG06782.1 - 1.4e-29 103.3 0.0 2.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06782.1 - 1.6e-10 41.3 1.5 1.4e-07 31.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AAG06782.1 - 0.0024 17.6 0.1 0.011 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 AAG06782.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 AAG06782.1 - 0.033 14.5 1.0 0.2 11.9 0.2 2.4 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 AAG06782.1 - 0.037 13.6 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 AAG06782.1 - 0.095 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG06782.1 - 0.3 11.5 5.8 1.5 9.2 5.8 2.2 1 1 0 1 1 1 0 AAA ATPase domain ABC2_membrane_2 PF12679.7 AAG06783.1 - 3.7e-38 131.5 22.9 3.4e-37 128.3 22.9 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAG06783.1 - 4.1e-11 43.2 7.3 4.1e-11 43.2 7.3 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AAG06783.1 - 7.5e-06 25.6 2.8 1.6e-05 24.6 2.8 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AAG06783.1 - 1.3e-05 24.5 16.5 1.3e-05 24.5 16.5 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein NosL PF05573.12 AAG06784.1 - 1.5e-45 154.7 0.0 1.8e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 NosL FAD_binding_6 PF00970.24 AAG06785.1 - 2e-09 37.7 0.0 5.6e-09 36.3 0.0 1.7 1 1 1 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AAG06785.1 - 5.3e-08 33.5 0.0 8.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 AAG06785.1 - 0.19 11.8 0.0 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain LysR_substrate PF03466.20 AAG06786.1 - 1.5e-57 194.4 1.9 2.4e-57 193.7 1.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06786.1 - 1.2e-17 63.6 5.9 1.4e-17 63.4 1.7 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAG06786.1 - 3.5e-10 39.3 0.0 8.3e-10 38.1 0.0 1.5 1 1 1 2 2 2 1 PBP superfamily domain DUF1375 PF07119.12 AAG06787.1 - 3.3e-15 56.2 0.6 5.1e-15 55.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1375) ABC2_membrane_3 PF12698.7 AAG06788.1 - 5.4e-29 101.4 7.6 3.9e-28 98.6 7.6 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAG06788.1 - 5.1e-16 58.7 13.5 9.4e-16 57.9 13.5 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAG06789.1 - 1.7e-21 76.8 9.2 3.8e-21 75.6 9.2 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAG06789.1 - 1e-08 34.8 14.4 2.4e-08 33.7 14.4 1.6 1 1 0 1 1 1 1 ABC-2 type transporter HlyD_D23 PF16576.5 AAG06790.1 - 4.1e-20 71.9 3.0 3.5e-18 65.6 3.0 2.1 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG06790.1 - 5.8e-11 42.1 3.2 5.8e-11 42.1 3.2 4.5 4 1 0 4 4 4 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAG06790.1 - 2.7e-08 34.4 0.0 1.8e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl PF00364.22 AAG06790.1 - 1.4e-06 28.1 0.0 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme DUF4407 PF14362.6 AAG06790.1 - 0.0081 15.6 18.2 0.1 11.9 6.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) PTS_EIIA_1 PF00358.20 AAG06790.1 - 0.012 15.3 0.0 0.071 12.9 0.0 2.1 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ABC_tran_CTD PF16326.5 AAG06790.1 - 0.016 15.4 9.1 0.19 12.0 3.4 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Golgin_A5 PF09787.9 AAG06790.1 - 0.033 13.7 9.3 0.048 13.1 9.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 AAG06790.1 - 0.09 12.3 4.4 0.13 11.8 4.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 AAG06790.1 - 0.11 12.7 8.2 0.25 11.6 2.3 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 AAG06790.1 - 0.51 10.9 7.7 2.5 8.7 3.6 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF724 PF05266.14 AAG06790.1 - 0.56 10.0 4.1 4.9 6.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 AAG06790.1 - 0.79 10.1 8.0 1.2 9.6 8.0 1.2 1 0 0 1 1 1 0 Fez1 TMF_TATA_bd PF12325.8 AAG06790.1 - 1.1 9.4 6.3 17 5.6 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.20 AAG06790.1 - 1.9 8.5 7.1 11 6.0 0.2 3.1 2 1 1 3 3 3 0 Prefoldin subunit PKcGMP_CC PF16808.5 AAG06790.1 - 2 8.3 8.4 1.9 8.4 1.8 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPR_MLP1_2 PF07926.12 AAG06790.1 - 2.2 8.4 19.0 1.4 9.0 3.1 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 AAG06790.1 - 3.1 8.3 10.9 9.2 6.8 3.4 2.2 1 1 0 2 2 2 0 Spectrin repeat DUF4200 PF13863.6 AAG06790.1 - 4 7.9 13.7 1e+02 3.4 13.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 AAG06790.1 - 4 7.6 11.2 51 4.0 11.3 2.1 1 1 0 1 1 1 0 Tropomyosin like Spc24 PF08286.11 AAG06790.1 - 4.4 7.6 8.5 60 4.0 0.0 3.7 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 PEP-utilisers_N PF05524.13 AAG06790.1 - 4.9 7.4 15.9 3.4 7.8 2.1 2.8 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal FlxA PF14282.6 AAG06790.1 - 5.2 7.1 12.4 0.21 11.6 0.4 2.6 2 1 0 2 2 2 0 FlxA-like protein Csm1_N PF18504.1 AAG06790.1 - 7.2 7.0 7.9 16 5.9 0.8 3.0 2 2 1 3 3 3 0 Csm1 N-terminal domain PsiE PF06146.12 AAG06791.1 - 2.7e-17 62.9 4.9 2.7e-17 62.9 4.9 1.5 2 0 0 2 2 2 1 Phosphate-starvation-inducible E Transglut_core2 PF13369.6 AAG06791.1 - 0.021 14.4 0.1 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily OEP PF02321.18 AAG06792.1 - 4.6e-48 163.5 38.5 1.2e-28 100.2 14.0 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein AvrPphF-ORF-2 PF09143.10 AAG06792.1 - 0.055 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 AvrPphF-ORF-2 HlyD PF00529.20 AAG06793.1 - 4.4e-19 68.1 0.1 8.7e-19 67.2 0.0 1.5 2 0 0 2 2 2 1 HlyD membrane-fusion protein of T1SS HlyD_3 PF13437.6 AAG06793.1 - 8.8e-19 68.2 0.2 2.3e-15 57.2 0.1 2.7 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAG06793.1 - 1.1e-11 44.4 1.7 1.9e-06 27.2 0.1 2.2 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG06793.1 - 7.8e-09 35.2 0.7 2.5e-06 27.2 0.1 3.7 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG06793.1 - 0.0018 18.1 0.2 0.08 12.8 0.0 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme HIP1_clath_bdg PF16515.5 AAG06793.1 - 0.043 14.4 9.2 0.18 12.4 2.6 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OEP PF02321.18 AAG06793.1 - 0.059 13.2 24.9 0.037 13.8 5.6 3.1 3 0 0 3 3 3 0 Outer membrane efflux protein Peptidase_M23 PF01551.22 AAG06793.1 - 0.18 12.0 0.4 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 Peptidase family M23 Atg14 PF10186.9 AAG06793.1 - 0.43 9.6 2.7 0.81 8.7 2.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med9 PF07544.13 AAG06793.1 - 1.6 8.9 5.3 13 6.0 0.8 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran PF00005.27 AAG06794.1 - 5.8e-30 104.6 0.0 9.3e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAG06794.1 - 3.2e-14 53.2 6.4 4.4e-14 52.8 6.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 AAG06794.1 - 3.1e-06 27.2 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG06794.1 - 0.00014 22.3 1.0 0.00039 20.8 1.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAG06794.1 - 0.00015 21.3 0.1 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AAG06794.1 - 0.00086 19.5 0.0 0.0049 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAG06794.1 - 0.013 15.3 0.3 0.033 13.9 0.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG06794.1 - 0.014 15.7 0.0 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAG06794.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 AAG06794.1 - 0.025 14.3 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain STAS_2 PF13466.6 AAG06794.1 - 0.029 14.7 5.5 0.11 12.8 0.7 3.8 3 0 0 3 3 3 0 STAS domain AAA_18 PF13238.6 AAG06794.1 - 0.064 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAG06794.1 - 0.078 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAG06794.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 AAG06794.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain HasA PF06438.12 AAG06795.1 - 1.9e-94 315.1 6.7 2.1e-94 314.9 6.7 1.0 1 0 0 1 1 1 1 Heme-binding protein A (HasA) TonB_dep_Rec PF00593.24 AAG06796.1 - 4.6e-50 171.8 25.7 6.5e-50 171.4 25.7 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG06796.1 - 4.7e-18 65.7 2.4 4.7e-18 65.7 2.4 2.2 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG06796.1 - 4.5e-05 23.1 0.0 0.00012 21.7 0.0 1.8 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AAG06797.1 - 3.8e-16 59.5 0.4 6.1e-16 58.8 0.4 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG06797.1 - 2.3e-10 40.2 9.8 2.3e-10 40.2 9.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AAG06797.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) Sigma70_r4_2 PF08281.12 AAG06798.1 - 1.5e-17 63.0 0.7 3e-17 62.0 0.7 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG06798.1 - 1.4e-13 50.4 2.4 3e-13 49.3 2.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG06798.1 - 4e-09 35.8 0.5 4e-09 35.8 0.5 2.6 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG06798.1 - 2.6e-08 34.0 2.2 3.2e-08 33.7 2.2 1.1 1 0 0 1 1 1 1 ECF sigma factor HTH_38 PF13936.6 AAG06798.1 - 0.0013 18.4 0.3 0.0024 17.6 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 AAG06798.1 - 0.0015 18.0 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family MarR_2 PF12802.7 AAG06798.1 - 0.0055 16.6 1.7 0.017 15.0 1.0 2.3 2 1 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAG06798.1 - 0.0077 16.3 0.6 0.0077 16.3 0.6 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AAG06798.1 - 0.0079 16.2 0.1 0.019 15.0 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_40 PF14493.6 AAG06798.1 - 0.021 15.3 0.1 0.066 13.7 0.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AAG06798.1 - 0.021 14.6 1.4 0.078 12.8 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 AAG06798.1 - 0.024 14.2 0.1 0.061 12.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 AAG06798.1 - 0.033 14.0 0.1 0.089 12.6 0.1 1.7 1 0 0 1 1 1 0 HTH DNA binding domain TnsD PF15978.5 AAG06798.1 - 0.034 13.1 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_11 PF08279.12 AAG06798.1 - 0.046 13.7 1.1 0.58 10.1 0.2 2.4 2 0 0 2 2 2 0 HTH domain Fe_dep_repress PF01325.19 AAG06798.1 - 0.089 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain SpoIIID PF12116.8 AAG06798.1 - 0.096 12.8 0.2 9.6 6.4 0.1 2.5 2 1 1 3 3 3 0 Stage III sporulation protein D HTH_31 PF13560.6 AAG06798.1 - 0.94 9.9 8.9 0.082 13.3 2.5 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain DUF2790 PF10976.8 AAG06800.1 - 3.9e-26 90.9 0.0 4.4e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2790) YebG PF07130.12 AAG06801.1 - 2.2e-26 91.5 3.0 2.8e-26 91.1 3.0 1.2 1 0 0 1 1 1 1 YebG protein HsdM_N PF12161.8 AAG06801.1 - 0.019 15.6 0.2 0.021 15.4 0.2 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain TetR_C_34 PF17929.1 AAG06801.1 - 0.077 13.1 0.1 0.11 12.6 0.1 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain 2-oxoacid_dh PF00198.23 AAG06803.1 - 2.3e-48 164.7 0.0 3.9e-47 160.6 0.0 2.0 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAG06803.1 - 9.9e-20 70.2 0.0 1.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 AAG06803.1 - 1.4e-13 50.9 0.1 3.2e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AAG06803.1 - 0.039 13.8 0.1 0.4 10.6 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.19 AAG06803.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein Transket_pyr PF02779.24 AAG06804.1 - 3.7e-48 163.6 0.1 4.8e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAG06804.1 - 4.7e-35 120.2 0.0 9.5e-35 119.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AAG06804.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 AAG06805.1 - 5e-81 271.9 0.0 6e-81 271.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 AAG06805.1 - 6.1e-09 35.5 0.0 4.3e-08 32.7 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AAG06805.1 - 0.00046 20.0 1.0 0.019 14.8 0.2 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4456 PF14644.6 AAG06805.1 - 0.0094 15.7 0.5 0.015 15.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) HTH_41 PF14502.6 AAG06805.1 - 0.021 14.5 0.1 0.048 13.4 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Heme_oxygenase PF01126.20 AAG06805.1 - 0.037 13.8 0.3 0.062 13.1 0.3 1.3 1 0 0 1 1 1 0 Heme oxygenase Penicillinase_R PF03965.16 AAG06805.1 - 0.073 13.4 0.1 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Penicillinase repressor ELFV_dehydrog_N PF02812.18 AAG06806.1 - 3.3e-22 78.7 0.0 6.1e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 AAG06806.1 - 2.1e-14 53.9 0.2 1.1e-08 35.1 0.0 2.3 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 AAG06806.1 - 3.4e-05 23.3 0.0 5.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAG06806.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 AAG06806.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 AAG06806.1 - 0.018 15.2 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAG06806.1 - 0.024 15.2 0.0 0.17 12.5 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AAG06806.1 - 0.056 13.3 0.8 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AAG06806.1 - 0.059 13.4 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short PF00106.25 AAG06806.1 - 0.098 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ThiF PF00899.21 AAG06806.1 - 0.11 11.9 0.7 0.17 11.2 0.7 1.2 1 0 0 1 1 1 0 ThiF family Transglut_core2 PF13369.6 AAG06807.1 - 1.1e-36 125.7 0.3 1.5e-36 125.3 0.3 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 AAG06807.1 - 3.2e-07 30.4 5.3 3.2e-07 30.4 5.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 AAG06808.1 - 1.7e-18 67.1 21.7 1.7e-18 67.1 21.7 2.2 2 0 0 2 2 2 1 MalT-like TPR region GerE PF00196.19 AAG06808.1 - 2.5e-16 59.0 0.0 4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_19 PF14559.6 AAG06808.1 - 5e-06 26.9 32.1 0.029 14.9 1.4 7.3 5 3 0 6 6 6 3 Tetratricopeptide repeat AAA_22 PF13401.6 AAG06808.1 - 0.00033 21.0 0.0 0.0014 19.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain Sigma70_r4_2 PF08281.12 AAG06808.1 - 0.00039 20.0 2.6 0.017 14.8 0.0 3.7 3 0 0 3 3 3 1 Sigma-70, region 4 TPR_12 PF13424.6 AAG06808.1 - 0.0031 17.8 50.0 0.0044 17.3 6.9 7.5 5 2 3 8 8 8 3 Tetratricopeptide repeat NACHT PF05729.12 AAG06808.1 - 0.0069 16.3 0.0 0.022 14.7 0.0 2.0 1 0 0 1 1 1 1 NACHT domain HTH_Tnp_Mu_2 PF09039.11 AAG06808.1 - 0.064 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain AAA_30 PF13604.6 AAG06808.1 - 0.083 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_24 PF13412.6 AAG06808.1 - 0.1 12.2 0.8 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF1329 PF07044.11 AAG06809.1 - 2.9e-152 507.2 5.5 3.3e-152 507.0 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) LolA_like PF17131.4 AAG06809.1 - 3.7e-06 26.8 0.0 0.0072 16.1 0.0 2.4 1 1 1 2 2 2 2 Outer membrane lipoprotein-sorting protein DUF1302 PF06980.11 AAG06810.1 - 1e-221 737.5 8.8 1.1e-221 737.4 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) HTH_18 PF12833.7 AAG06811.1 - 1.2e-19 70.3 0.8 7.1e-19 67.9 0.2 2.4 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06811.1 - 7.8e-13 48.2 0.3 6.6e-09 35.7 0.1 2.7 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family SnoaL_2 PF12680.7 AAG06811.1 - 2.5e-10 40.9 0.3 5.3e-10 39.9 0.3 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAG06811.1 - 0.00013 22.3 0.1 0.00029 21.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 AAG06811.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Homeodomain PF00046.29 AAG06811.1 - 0.0067 16.3 0.2 2.2 8.2 0.0 2.7 2 1 0 2 2 2 2 Homeodomain SnoaL_3 PF13474.6 AAG06811.1 - 0.09 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain DAO PF01266.24 AAG06812.1 - 6.5e-48 164.1 5.0 7.9e-48 163.8 5.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG06812.1 - 2.1e-08 33.7 0.1 3.9e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 AAG06812.1 - 0.00016 21.8 1.0 0.00036 20.7 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG06812.1 - 0.0012 18.1 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG06812.1 - 0.012 14.8 0.5 0.02 14.0 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 AAG06812.1 - 0.018 15.6 0.0 0.23 12.1 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAG06812.1 - 0.03 14.3 0.1 0.075 13.0 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAG06812.1 - 0.043 12.9 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 AAG06812.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 AAG06812.1 - 0.081 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 AAG06812.1 - 0.089 11.5 0.0 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Cupin_3 PF05899.12 AAG06813.1 - 6e-29 99.5 0.1 7.4e-29 99.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AAG06813.1 - 6.2e-05 22.6 0.0 8.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AAG06813.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 AAG06813.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain EutQ PF06249.12 AAG06813.1 - 0.087 12.6 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ ECH_1 PF00378.20 AAG06814.1 - 8.6e-41 139.9 0.0 9.9e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG06814.1 - 7.8e-21 74.9 0.1 1.3e-20 74.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 AAG06814.1 - 0.0046 16.9 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 adh_short PF00106.25 AAG06815.1 - 1.7e-40 138.6 1.0 2.9e-40 137.8 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG06815.1 - 1.2e-34 119.9 0.3 1.7e-34 119.5 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG06815.1 - 1.6e-17 64.0 0.9 2.2e-17 63.5 0.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 AAG06815.1 - 0.0015 18.4 0.8 0.029 14.3 0.8 2.2 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 AAG06815.1 - 0.0019 17.7 0.5 0.0029 17.1 0.5 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glucodextran_B PF09136.10 AAG06815.1 - 0.068 13.5 1.7 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Glucodextranase, domain B Gram_pos_anchor PF00746.21 AAG06816.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF4131 PF13567.6 AAG06816.1 - 0.95 9.1 9.3 4.1 7.0 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Abhydrolase_6 PF12697.7 AAG06817.1 - 1.4e-17 65.0 10.9 1.8e-17 64.7 10.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG06817.1 - 4.1e-17 62.7 0.1 5.6e-14 52.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06817.1 - 0.00014 21.2 0.0 0.00023 20.5 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 AAG06817.1 - 0.21 10.6 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Aldolase_II PF00596.21 AAG06818.1 - 2.9e-43 148.0 0.3 3.5e-43 147.7 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LrgB PF04172.16 AAG06819.1 - 7.7e-70 234.7 7.5 8.7e-70 234.6 7.5 1.0 1 0 0 1 1 1 1 LrgB-like family DUF1614 PF07758.11 AAG06819.1 - 0.11 12.5 3.2 0.15 12.0 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1614) DUF2085 PF09858.9 AAG06819.1 - 0.37 11.3 4.8 1 9.9 0.6 2.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) LrgA PF03788.14 AAG06820.1 - 9.5e-25 86.4 11.1 1.2e-24 86.0 11.1 1.1 1 0 0 1 1 1 1 LrgA family PaRep2a PF07903.11 AAG06820.1 - 0.049 13.5 0.2 0.084 12.7 0.2 1.3 1 0 0 1 1 1 0 PaRep2a protein ABC_membrane PF00664.23 AAG06820.1 - 0.24 11.0 5.0 0.43 10.2 1.5 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region LysR_substrate PF03466.20 AAG06821.1 - 2.5e-45 154.4 5.4 3.7e-45 153.8 5.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06821.1 - 9.7e-21 73.5 1.3 9.7e-21 73.5 1.3 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Transposase_20 PF02371.16 AAG06822.1 - 7.2e-25 87.1 0.7 1.9e-24 85.8 0.7 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAG06822.1 - 5.4e-15 55.6 0.2 2.4e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 Transposase Cep57_MT_bd PF06657.13 AAG06822.1 - 0.0024 18.3 0.5 0.0056 17.1 0.1 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 HHH PF00633.23 AAG06822.1 - 0.02 14.7 0.1 0.063 13.2 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lzipper-MIP1 PF14389.6 AAG06822.1 - 0.021 15.1 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_transf_4 PF13439.6 AAG06822.1 - 0.054 13.5 0.4 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HalX PF08663.10 AAG06822.1 - 0.095 13.0 1.6 0.33 11.3 1.6 1.9 1 0 0 1 1 1 0 HalX domain DUF3287 PF11690.8 AAG06822.1 - 0.11 12.2 0.6 0.31 10.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ABC_tran_CTD PF16326.5 AAG06822.1 - 0.12 12.6 1.5 0.25 11.6 1.5 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AAG06822.1 - 0.4 10.8 3.0 0.23 11.5 0.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation Flavodoxin_1 PF00258.25 AAG06823.1 - 7.4e-20 71.6 0.0 8.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.15 AAG06823.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_NdrI PF07972.11 AAG06823.1 - 0.026 14.7 0.0 0.042 14.0 0.0 1.3 1 1 0 1 1 1 0 NrdI Flavodoxin like DUF3726 PF12525.8 AAG06823.1 - 0.094 12.8 0.0 3.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) ABM PF03992.16 AAG06824.1 - 0.0009 19.3 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase adh_short_C2 PF13561.6 AAG06825.1 - 2.7e-26 92.6 0.0 3.1e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06825.1 - 3.2e-26 92.0 0.0 3.9e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG06825.1 - 4.6e-05 23.4 0.1 6.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 AAG06825.1 - 0.073 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family GTP_cyclohydroI PF01227.22 AAG06826.1 - 6.1e-76 253.8 0.3 6.8e-76 253.7 0.3 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I DAO_C PF16901.5 AAG06826.1 - 0.017 15.0 0.6 0.14 12.1 0.6 2.0 1 1 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase MAPKK1_Int PF08923.10 AAG06826.1 - 0.028 14.2 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting F_bP_aldolase PF01116.20 AAG06826.1 - 0.062 12.8 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II QueF PF14489.6 AAG06826.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein FolB PF02152.18 AAG06827.1 - 2e-25 89.5 1.4 2.2e-25 89.3 1.4 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase DUF1244 PF06844.11 AAG06828.1 - 1.7e-38 130.6 1.0 2.9e-38 129.8 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1244) Terminase_4 PF05119.12 AAG06828.1 - 0.023 15.1 0.2 0.032 14.7 0.2 1.3 1 1 0 1 1 1 0 Phage terminase, small subunit DUF4186 PF13811.6 AAG06828.1 - 0.11 12.6 0.2 0.2 11.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4186) TOBE PF03459.17 AAG06829.1 - 3.7e-16 59.2 0.6 4.1e-16 59.0 0.6 1.0 1 0 0 1 1 1 1 TOBE domain ABC_tran PF00005.27 AAG06830.1 - 3.8e-30 105.2 0.0 5e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06830.1 - 1e-05 25.5 0.1 0.0035 17.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 AAG06830.1 - 0.00022 21.5 0.5 0.088 13.1 0.1 2.4 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 AAG06830.1 - 0.00026 20.5 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG06830.1 - 0.00031 21.0 0.0 0.00077 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG06830.1 - 0.0004 20.8 1.7 0.0012 19.3 1.7 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 AAG06830.1 - 0.00049 20.3 0.0 0.0012 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAG06830.1 - 0.00051 19.7 0.4 0.0098 15.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAG06830.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAG06830.1 - 0.0024 17.9 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 AAG06830.1 - 0.0035 17.1 0.0 0.0079 15.9 0.0 1.6 1 1 1 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AAG06830.1 - 0.0042 15.9 0.1 1.6 7.4 0.0 2.7 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 AAG06830.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 AAG06830.1 - 0.023 14.1 0.0 3.6 6.9 0.0 2.1 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 AAG06830.1 - 0.028 13.6 0.1 0.073 12.2 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 AAG06830.1 - 0.03 14.8 0.0 0.057 13.9 0.0 1.4 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 AAG06830.1 - 0.032 14.2 0.2 0.098 12.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 AAG06830.1 - 0.089 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 AAG06830.1 - 0.16 11.6 0.1 0.74 9.4 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain BPD_transp_1 PF00528.22 AAG06831.1 - 4.3e-25 88.5 14.5 4.3e-25 88.5 14.5 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 AAG06831.1 - 0.013 15.9 0.8 0.041 14.2 0.8 1.8 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF3169 PF11368.8 AAG06831.1 - 0.098 12.2 0.9 0.19 11.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Bac_luciferase PF00296.20 AAG06832.1 - 7.2e-85 285.2 8.0 8.3e-85 285.0 8.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sulf_coat_C PF12193.8 AAG06832.1 - 0.073 13.1 0.8 2.5 8.2 0.0 2.6 3 0 0 3 3 3 0 Sulfolobus virus coat protein C terminal RNA_pol_Rpo13 PF12136.8 AAG06832.1 - 0.19 11.7 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain NMT1_2 PF13379.6 AAG06833.1 - 1e-16 61.4 0.1 3.6e-16 59.6 0.1 1.8 1 1 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAG06833.1 - 2.3e-16 60.4 0.0 3.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like OpuAC PF04069.12 AAG06833.1 - 4e-09 36.4 0.0 5.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_3 PF00497.20 AAG06833.1 - 1.3e-06 28.0 0.0 5.2e-06 26.1 0.0 1.8 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAG06833.1 - 1.9e-05 24.4 0.0 3.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 AAG06833.1 - 2.2e-05 24.1 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family FR47 PF08445.10 AAG06833.1 - 0.079 12.9 0.1 2 8.4 0.1 2.4 2 0 0 2 2 2 0 FR47-like protein FMN_red PF03358.15 AAG06834.1 - 2.9e-31 108.3 0.2 3.7e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AAG06834.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin-like fold ABC_tran PF00005.27 AAG06835.1 - 4.9e-29 101.6 0.0 7.2e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06835.1 - 6.2e-06 26.2 0.1 0.013 15.3 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 AAG06835.1 - 0.00075 18.4 0.1 0.074 11.8 0.0 2.8 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAG06835.1 - 0.0014 19.0 0.3 0.004 17.6 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG06835.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG06835.1 - 0.01 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 AAG06835.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 AAG06835.1 - 0.028 14.7 0.1 0.63 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAG06835.1 - 0.046 14.0 0.1 0.36 11.1 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 AAG06835.1 - 0.11 12.1 0.1 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAG06835.1 - 0.12 12.9 0.0 1.3 9.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAG06835.1 - 0.17 11.9 0.0 0.6 10.1 0.0 1.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAG06835.1 - 0.18 11.7 0.1 0.51 10.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 AAG06835.1 - 0.19 11.9 0.3 0.98 9.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAG06835.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 AAG06835.1 - 0.27 10.4 0.0 0.43 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain BPD_transp_1 PF00528.22 AAG06836.1 - 3.5e-25 88.8 8.7 3.5e-25 88.8 8.7 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Gram_pos_anchor PF00746.21 AAG06836.1 - 0.28 11.2 2.1 7.5 6.6 0.8 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif NMT1 PF09084.11 AAG06837.1 - 8.6e-26 91.2 0.0 1.2e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAG06837.1 - 1.5e-09 38.0 0.0 5.2e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAG06837.1 - 1.6e-09 37.8 0.0 2.6e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 AAG06837.1 - 3.9e-06 26.5 0.0 7.8e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAG06837.1 - 1e-05 25.1 0.0 2.4e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 YhfZ_C PF14503.6 AAG06837.1 - 0.029 13.9 0.0 0.065 12.8 0.0 1.6 1 1 0 1 1 1 0 YhfZ C-terminal domain VitK2_biosynth PF02621.14 AAG06837.1 - 0.038 13.5 0.2 0.084 12.4 0.0 1.5 2 0 0 2 2 2 0 Menaquinone biosynthesis OpuAC PF04069.12 AAG06837.1 - 0.052 13.1 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system AhpC-TSA PF00578.21 AAG06838.1 - 7.8e-31 106.6 0.0 1e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG06838.1 - 3e-15 56.2 0.0 3.8e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AAG06838.1 - 4.7e-12 45.6 0.0 8.1e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_8 PF13905.6 AAG06838.1 - 0.0022 18.3 0.0 0.025 14.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA_2 PF13911.6 AAG06838.1 - 0.04 14.0 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Mqo PF06039.15 AAG06840.1 - 2.1e-242 805.0 0.0 2.4e-242 804.8 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 AAG06840.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF480 PF04337.12 AAG06841.1 - 2e-55 187.0 0.7 3.4e-55 186.3 0.1 1.7 2 1 1 3 3 3 1 Protein of unknown function, DUF480 HTH_5 PF01022.20 AAG06841.1 - 0.022 14.6 0.6 1 9.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family ABC_tran_CTD PF16326.5 AAG06841.1 - 0.051 13.8 4.2 0.29 11.4 4.2 2.3 1 1 0 1 1 1 0 ABC transporter C-terminal domain CLZ PF16526.5 AAG06841.1 - 0.079 13.3 3.3 0.082 13.3 0.3 2.4 2 2 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cdc6_C PF09079.11 AAG06841.1 - 0.1 12.6 0.5 15 5.6 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain MarR_2 PF12802.7 AAG06841.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.2 4 0 0 4 4 4 0 MarR family BLACT_WH PF17778.1 AAG06841.1 - 0.43 10.6 2.5 13 5.8 0.3 2.5 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain SlyX PF04102.12 AAG06841.1 - 0.54 10.9 4.8 0.49 11.0 0.5 2.6 2 1 0 2 2 2 0 SlyX Sugarporin_N PF11471.8 AAG06841.1 - 5.1 7.1 10.8 22 5.1 10.8 2.1 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Vir_act_alpha_C PF10400.9 AAG06841.1 - 7 7.4 10.2 2.5 8.8 1.2 3.1 1 1 1 2 2 2 0 Virulence activator alpha C-term Thiolase_N PF00108.23 AAG06842.1 - 2e-67 227.3 0.2 3.3e-67 226.6 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG06842.1 - 9e-46 154.5 0.0 1.8e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG06842.1 - 3.8e-06 26.7 1.0 3.8e-06 26.7 1.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain PPK2 PF03976.14 AAG06843.1 - 1.6e-153 508.7 11.2 3.3e-99 331.0 5.3 2.0 2 0 0 2 2 2 2 Polyphosphate kinase 2 (PPK2) Zeta_toxin PF06414.12 AAG06843.1 - 0.00068 19.0 0.0 0.018 14.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 AAG06843.1 - 0.0013 19.2 2.6 1 9.9 0.1 3.4 2 1 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 AAG06843.1 - 0.0016 18.1 0.0 0.8 9.4 0.0 3.2 3 0 0 3 3 3 1 Thymidylate kinase MT0933_antitox PF14013.6 AAG06843.1 - 0.075 13.3 2.3 2 8.8 0.0 2.9 3 0 0 3 3 3 0 MT0933-like antitoxin protein SRP54_N PF02881.19 AAG06843.1 - 0.12 12.6 0.1 0.47 10.7 0.1 2.1 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain DAO PF01266.24 AAG06844.1 - 6.5e-49 167.4 4.6 9.6e-49 166.8 4.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Methyltransf_30 PF05430.11 AAG06844.1 - 4.7e-45 152.5 0.0 7.2e-45 151.9 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase NAD_binding_8 PF13450.6 AAG06844.1 - 8.4e-07 29.1 0.3 1.6e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAG06844.1 - 5e-05 23.8 0.0 9.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG06844.1 - 0.00013 21.2 1.6 0.00023 20.4 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAG06844.1 - 0.00021 20.5 1.0 0.00032 19.9 1.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAG06844.1 - 0.00023 20.5 0.4 0.00036 19.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAG06844.1 - 0.00083 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG06844.1 - 0.0026 17.2 0.8 0.0037 16.7 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAG06844.1 - 0.016 14.3 0.7 0.028 13.5 0.7 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 AAG06844.1 - 0.017 13.8 0.3 0.024 13.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 AAG06844.1 - 0.056 13.3 0.2 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AAG06844.1 - 0.22 11.1 0.6 0.39 10.3 0.6 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TauE PF01925.19 AAG06845.1 - 1.2e-40 139.7 47.9 1.3e-40 139.5 47.9 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2165 PF09933.9 AAG06845.1 - 0.004 17.2 5.7 0.0092 16.0 5.7 1.6 1 0 0 1 1 1 1 Predicted small integral membrane protein (DUF2165) SepZ PF06066.11 AAG06845.1 - 0.25 11.6 0.2 0.25 11.6 0.2 3.6 4 1 0 4 4 4 0 SepZ MarR PF01047.22 AAG06846.1 - 4.8e-17 61.6 0.7 1.9e-16 59.7 0.3 1.9 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AAG06846.1 - 1.1e-11 44.4 2.2 1.1e-11 44.4 2.2 2.2 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 AAG06846.1 - 5.2e-09 36.5 0.1 1e-08 35.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_34 PF13601.6 AAG06846.1 - 5.9e-06 26.4 0.0 9.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AAG06846.1 - 3.4e-05 23.6 0.0 5.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 AAG06846.1 - 3.8e-05 23.7 1.5 3.8e-05 23.7 1.5 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AAG06846.1 - 4e-05 23.4 0.6 6.1e-05 22.8 0.6 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TFIIE_alpha PF02002.17 AAG06846.1 - 0.00027 20.8 0.1 0.00047 20.0 0.1 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_24 PF13412.6 AAG06846.1 - 0.00065 19.2 1.0 0.0011 18.4 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAG06846.1 - 0.003 17.5 2.1 0.0077 16.2 1.3 2.2 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain PadR PF03551.14 AAG06846.1 - 0.003 17.5 0.1 0.0076 16.2 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_AsnC-type PF13404.6 AAG06846.1 - 0.018 14.9 2.8 0.1 12.4 0.3 2.8 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 AAG06846.1 - 0.024 14.4 2.9 0.024 14.4 2.9 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain Dimerisation2 PF16864.5 AAG06846.1 - 0.1 12.6 0.3 0.23 11.4 0.2 1.5 1 1 0 1 1 1 0 Dimerisation domain Rrf2 PF02082.20 AAG06846.1 - 0.13 12.7 0.3 0.32 11.4 0.1 1.7 1 1 1 2 2 2 0 Transcriptional regulator RPA_C PF08784.11 AAG06846.1 - 0.16 12.6 0.0 0.32 11.7 0.0 1.6 2 0 0 2 2 2 0 Replication protein A C terminal GntR PF00392.21 AAG06846.1 - 0.87 9.3 4.3 0.49 10.1 1.2 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Asn_synthase PF00733.21 AAG06847.1 - 1.4e-80 271.6 0.1 1.8e-80 271.3 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAG06847.1 - 2.1e-43 147.2 0.0 3.4e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAG06847.1 - 3.6e-40 137.3 0.0 1.8e-38 131.8 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain tRNA_Me_trans PF03054.16 AAG06847.1 - 0.03 13.1 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase DUF3700 PF12481.8 AAG06847.1 - 0.037 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein RimK PF08443.11 AAG06848.1 - 6e-15 55.3 0.0 4.7e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Acetyltransf_1 PF00583.25 AAG06848.1 - 1.1e-11 45.0 0.0 6.8e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG06848.1 - 6.8e-10 39.2 0.0 1.8e-08 34.7 0.0 2.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG06848.1 - 1.2e-07 31.7 0.0 2.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATP-grasp_3 PF02655.14 AAG06848.1 - 9.7e-07 29.0 0.0 1.6e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain FR47 PF08445.10 AAG06848.1 - 9.9e-07 28.6 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Dala_Dala_lig_C PF07478.13 AAG06848.1 - 3e-06 26.9 0.0 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus GSH-S_ATP PF02955.16 AAG06848.1 - 4.2e-06 26.3 0.0 7.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAG06848.1 - 1.1e-05 24.9 0.0 0.00092 18.5 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 AAG06848.1 - 1.2e-05 24.7 0.1 0.0038 16.5 0.0 2.9 2 2 2 4 4 4 1 Sugar-transfer associated ATP-grasp Acetyltransf_3 PF13302.7 AAG06848.1 - 0.00027 21.6 0.0 0.00058 20.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAG06848.1 - 0.0067 16.6 3.2 0.013 15.6 0.0 3.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG06848.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.17 AAG06848.1 - 0.013 15.0 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Peptidase_M42 PF05343.14 AAG06849.1 - 8.2e-74 248.2 0.0 9.6e-74 248.0 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 AAG06849.1 - 6e-09 35.9 0.0 1.4e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 7TMR-DISM_7TM PF07695.11 AAG06850.1 - 3.8e-35 121.7 29.0 5.7e-35 121.1 29.0 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling HATPase_c PF02518.26 AAG06850.1 - 1.1e-32 112.9 0.0 1.8e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 7TMR-DISMED2 PF07696.11 AAG06850.1 - 1.8e-32 112.2 0.0 3.4e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 7TMR-DISM extracellular 2 Response_reg PF00072.24 AAG06850.1 - 2.2e-22 79.4 0.0 8e-22 77.5 0.0 2.0 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 AAG06850.1 - 4.8e-20 71.4 0.0 1.7e-19 69.6 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain UPF0270 PF06794.12 AAG06851.1 - 2.6e-25 88.3 0.0 3e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0270) DUF3105 PF11303.8 AAG06851.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) MFS_3 PF05977.13 AAG06853.1 - 9.1e-220 730.5 27.0 1.1e-219 730.2 27.0 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AAG06853.1 - 6.5e-27 94.4 70.7 1.4e-22 80.2 39.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAG06853.1 - 0.046 12.6 19.9 0.11 11.4 17.1 3.1 1 1 1 2 2 2 0 MFS_1 like family DEAD PF00270.29 AAG06854.1 - 1.4e-47 161.7 0.1 2.1e-46 157.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG06854.1 - 9.3e-30 103.2 0.2 1e-28 99.9 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAG06854.1 - 1.1e-08 35.3 0.0 3.1e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AAG06854.1 - 0.013 15.8 1.1 0.059 13.6 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 AAG06854.1 - 0.013 15.8 0.3 0.2 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain RMMBL PF07521.12 AAG06854.1 - 0.015 15.2 0.0 17 5.5 0.0 3.5 3 0 0 3 3 3 0 Zn-dependent metallo-hydrolase RNA specificity domain Z1 PF10593.9 AAG06854.1 - 0.069 12.6 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Z1 domain MFS_1 PF07690.16 AAG06855.1 - 1.8e-49 168.6 56.9 7.4e-44 150.1 37.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG06855.1 - 3.7e-49 167.8 19.6 5e-49 167.4 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 AAG06855.1 - 7e-05 22.3 27.4 0.00011 21.6 4.3 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AAG06855.1 - 0.0024 16.3 2.6 0.0024 16.3 2.6 3.3 2 2 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 AAG06855.1 - 0.0036 15.8 0.6 0.0036 15.8 0.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MS_channel PF00924.18 AAG06856.1 - 6.9e-45 153.1 0.0 3.8e-44 150.7 0.0 2.0 1 1 0 1 1 1 1 Mechanosensitive ion channel MTABC_N PF16185.5 AAG06856.1 - 0.027 14.0 2.2 0.042 13.4 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region RibD_C PF01872.17 AAG06857.1 - 1.9e-20 73.6 0.0 1e-13 51.6 0.1 2.0 1 1 1 2 2 2 2 RibD C-terminal domain DHFR_1 PF00186.19 AAG06857.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase NUDIX PF00293.28 AAG06858.1 - 1.1e-12 48.1 0.1 1.9e-12 47.4 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 AAG06858.1 - 0.016 14.8 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Malic_M PF03949.15 AAG06859.1 - 4.2e-105 350.7 0.3 5.6e-105 350.2 0.3 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 AAG06859.1 - 2.2e-77 259.0 0.0 3.8e-77 258.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NLPC_P60 PF00877.19 AAG06860.1 - 3.7e-32 110.5 0.0 4.9e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 AAG06860.1 - 0.00049 20.2 0.0 0.17 12.0 0.0 2.5 1 1 1 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family LRAT PF04970.13 AAG06860.1 - 0.0015 18.8 0.1 0.0099 16.2 0.0 2.0 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DUF1175 PF06672.11 AAG06860.1 - 0.002 17.9 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1175) CHAP PF05257.16 AAG06860.1 - 0.0042 17.6 0.0 0.0069 16.9 0.0 1.4 1 0 0 1 1 1 1 CHAP domain DUF1287 PF06940.11 AAG06860.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1287) Amidase_6 PF12671.7 AAG06860.1 - 0.13 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative amidase domain EamA PF00892.20 AAG06861.1 - 1.3e-09 38.4 32.2 5.3e-05 23.4 11.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family RseC_MucC PF04246.12 AAG06861.1 - 3.6 7.6 20.9 0.75 9.7 1.7 4.0 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC DUF412 PF04217.13 AAG06861.1 - 7.4 6.5 8.0 0.22 11.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF412 EamA PF00892.20 AAG06862.1 - 2.4e-21 76.3 21.5 1.1e-10 41.8 12.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF2929 PF11151.8 AAG06862.1 - 0.091 13.1 2.7 0.63 10.4 1.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) ABC2_membrane_5 PF13346.6 AAG06862.1 - 4.8 6.7 7.7 1.3 8.6 4.6 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein SBP_bac_3 PF00497.20 AAG06863.1 - 3.8e-40 137.7 0.0 4.4e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG06863.1 - 1.1e-05 25.6 0.1 0.0013 18.9 0.0 2.8 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Autoind_synth PF00765.17 AAG06864.1 - 5.4e-20 71.7 0.0 9.2e-20 70.9 0.0 1.3 1 1 0 1 1 1 1 Autoinducer synthase Acetyltransf_5 PF13444.6 AAG06864.1 - 1.7e-05 25.5 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_bind PF03472.15 AAG06865.1 - 5e-36 123.4 0.0 6.8e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AAG06865.1 - 1.6e-19 69.2 0.0 2.4e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG06865.1 - 0.0002 21.0 0.2 0.00044 19.9 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG06865.1 - 0.0062 16.0 0.3 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG06865.1 - 0.046 13.5 0.0 0.046 13.5 0.0 1.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_20 PF12840.7 AAG06865.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AAG06865.1 - 0.092 12.5 0.2 0.092 12.5 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Glyco_transf_28 PF03033.20 AAG06866.1 - 8.4e-28 97.2 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 AAG06866.1 - 9.4e-05 21.4 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Abhydrolase_1 PF00561.20 AAG06867.1 - 8e-08 32.2 0.1 6.4e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06867.1 - 0.00091 18.6 0.1 0.0022 17.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Imm32 PF15566.6 AAG06867.1 - 0.012 15.4 0.1 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Immunity protein 32 TPR_2 PF07719.17 AAG06867.1 - 0.13 12.5 0.1 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat dUTPase PF00692.19 AAG06868.1 - 1.6e-09 37.5 0.0 9.8e-09 35.0 0.0 1.9 1 1 1 2 2 2 1 dUTPase Flagellar_put PF12611.8 AAG06868.1 - 0.074 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative flagellar ParA PF10609.9 AAG06869.1 - 5.1e-100 334.0 0.1 6.2e-100 333.7 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AAG06869.1 - 1.4e-16 60.7 0.0 3e-16 59.6 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FeS_assembly_P PF01883.19 AAG06869.1 - 1.9e-16 60.0 0.0 6.2e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein AAA_31 PF13614.6 AAG06869.1 - 1.7e-10 41.1 0.3 2e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 AAG06869.1 - 2e-08 34.0 0.2 2.8e-07 30.3 0.2 2.3 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 AAG06869.1 - 6.6e-08 32.2 0.2 2.1e-07 30.5 0.2 1.9 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AAG06869.1 - 1.8e-05 24.1 2.3 9.1e-05 21.8 0.4 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase VirC1 PF07015.11 AAG06869.1 - 0.00025 20.4 0.4 0.0022 17.3 0.1 2.0 2 0 0 2 2 2 1 VirC1 protein MeaB PF03308.16 AAG06869.1 - 0.00078 18.5 0.2 0.0015 17.6 0.2 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 AAG06869.1 - 0.00083 19.2 1.2 0.36 10.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 AAG06869.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AAG06869.1 - 0.0046 16.6 0.1 0.0091 15.6 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 AAG06869.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FTHFS PF01268.19 AAG06869.1 - 0.013 13.7 0.2 0.02 13.1 0.2 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase CBP_BcsQ PF06564.12 AAG06869.1 - 0.074 12.5 0.7 0.2 11.1 0.2 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ tRNA-synt_1g PF09334.11 AAG06870.1 - 3.7e-155 516.5 0.0 4.6e-155 516.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 AAG06870.1 - 1.4e-20 73.2 0.0 3.6e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 AAG06870.1 - 4.4e-12 45.1 0.2 1.2e-08 33.8 0.0 2.7 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AAG06870.1 - 6.7e-10 38.8 0.0 4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAG06870.1 - 1.2e-05 24.5 0.0 0.00098 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 AAG06870.1 - 0.0023 17.9 0.1 0.004 17.1 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF4349 PF14257.6 AAG06871.1 - 2.1e-24 86.1 4.4 2.9e-24 85.7 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) HAUS-augmin3 PF14932.6 AAG06871.1 - 0.0017 18.0 2.9 0.0021 17.7 2.9 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 IFT20 PF14931.6 AAG06871.1 - 0.036 14.2 0.9 0.064 13.4 0.9 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Leu_zip PF15294.6 AAG06871.1 - 0.069 12.7 0.7 0.094 12.2 0.7 1.1 1 0 0 1 1 1 0 Leucine zipper Spc7 PF08317.11 AAG06871.1 - 0.33 9.8 3.7 0.44 9.4 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS6_N PF14661.6 AAG06871.1 - 2.1 7.9 6.6 4.2 6.9 6.5 1.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Glycos_trans_3N PF02885.17 AAG06872.1 - 0.077 12.9 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Phage_GPD PF05954.11 AAG06874.1 - 8.6e-79 265.0 1.0 8.6e-79 265.0 1.0 1.7 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 AAG06874.1 - 0.00027 20.8 0.2 0.00093 19.1 0.1 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) PLDc PF00614.22 AAG06875.1 - 1.1e-16 60.3 0.9 1.6e-07 31.2 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 AAG06875.1 - 4.5e-09 36.3 0.0 3e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 PLD-like domain FokI_C PF02980.16 AAG06875.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain Tli4_C PF18426.1 AAG06876.1 - 1.5e-09 38.4 0.0 3.3e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Tle cognate immunity protein 4 C-terminal domain Rnf-Nqr PF02508.14 AAG06877.1 - 5.7e-61 205.5 18.7 6.3e-61 205.4 18.7 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein MtrF PF09472.10 AAG06877.1 - 0.18 11.2 0.2 0.18 11.2 0.2 3.7 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Colicin_V PF02674.16 AAG06877.1 - 2.6 8.0 16.2 0.18 11.8 6.6 2.4 1 1 1 2 2 2 0 Colicin V production protein Clc-like PF07062.12 AAG06877.1 - 5.7 6.4 8.4 0.32 10.4 1.1 2.0 1 1 1 2 2 2 0 Clc-like Fer4_21 PF14697.6 AAG06878.1 - 2.4e-17 62.8 15.5 2.4e-17 62.8 15.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain FeS PF04060.13 AAG06878.1 - 5.5e-14 51.5 6.1 5.5e-14 51.5 6.1 2.2 2 0 0 2 2 1 1 Putative Fe-S cluster Fer4 PF00037.27 AAG06878.1 - 1.6e-09 37.2 28.7 2.9e-06 26.9 5.8 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAG06878.1 - 3.2e-07 30.8 17.5 0.0033 18.0 0.6 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG06878.1 - 3.8e-07 30.2 33.3 1.3e-05 25.3 14.9 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG06878.1 - 4.6e-06 27.5 17.6 0.00031 21.6 2.3 3.0 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AAG06878.1 - 1.3e-05 25.2 13.6 1.3e-05 25.2 13.6 3.1 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG06878.1 - 0.0039 17.2 4.9 0.0039 17.2 4.9 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_2 PF12797.7 AAG06878.1 - 0.005 16.9 22.0 0.0053 16.8 3.3 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAG06878.1 - 0.0065 17.3 4.7 0.0065 17.3 4.7 4.0 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_22 PF17179.4 AAG06878.1 - 0.064 14.1 0.7 0.064 14.1 0.7 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG06878.1 - 0.12 12.9 20.6 0.44 11.0 2.7 2.8 1 1 3 4 4 4 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAG06878.1 - 0.23 11.7 14.7 0.45 10.7 3.2 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG06878.1 - 1.7 9.3 24.9 1 10.0 2.8 3.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG06878.1 - 2.4 8.9 25.0 0.35 11.5 4.1 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain Complex1_51K PF01512.17 AAG06879.1 - 2.3e-48 163.9 0.0 5e-48 162.8 0.0 1.6 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit RnfC_N PF13375.6 AAG06879.1 - 2.2e-32 111.0 0.0 5.1e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Fer4_8 PF13183.6 AAG06879.1 - 2.1e-09 37.7 15.9 4.1e-08 33.5 5.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAG06879.1 - 1.4e-08 35.2 4.0 4.4e-08 33.6 4.0 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG06879.1 - 1.6e-08 34.5 14.8 1.9e-07 31.0 7.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain SLBB PF10531.9 AAG06879.1 - 4.2e-08 32.9 0.2 9.8e-08 31.8 0.2 1.7 1 0 0 1 1 1 1 SLBB domain Fer4_16 PF13484.6 AAG06879.1 - 7.2e-07 30.1 6.8 0.012 16.5 0.9 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 AAG06879.1 - 1.1e-06 28.2 14.9 0.0015 18.2 2.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAG06879.1 - 4.3e-06 27.2 8.6 9e-05 22.9 8.8 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG06879.1 - 3.6e-05 23.8 10.9 0.0002 21.4 10.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAG06879.1 - 0.0002 21.3 16.0 0.018 15.1 2.5 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 AAG06879.1 - 0.0012 19.6 8.0 0.039 14.8 1.3 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG06879.1 - 0.0017 18.7 10.9 0.033 14.7 1.3 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAG06879.1 - 0.002 18.9 16.9 0.11 13.5 3.8 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAG06879.1 - 0.0041 17.3 8.2 0.17 12.1 0.7 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG06879.1 - 0.0042 17.1 17.4 0.1 12.7 4.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAG06879.1 - 0.022 14.9 13.1 0.13 12.4 12.3 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain NQRA PF05896.11 AAG06879.1 - 0.023 14.1 0.0 1.5 8.2 0.0 2.7 2 1 1 3 3 3 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) NQR2_RnfD_RnfE PF03116.15 AAG06880.1 - 2.9e-102 342.0 4.6 3.4e-102 341.8 4.6 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family FMN_bind PF04205.14 AAG06881.1 - 1.3e-17 64.2 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 FMN-binding domain BES1_N PF05687.13 AAG06881.1 - 0.23 11.8 0.1 0.45 10.9 0.1 1.4 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Rnf-Nqr PF02508.14 AAG06882.1 - 4.8e-62 209.0 9.1 5.5e-62 208.8 9.1 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein Ammonium_transp PF00909.21 AAG06882.1 - 0.0022 16.8 0.4 0.0031 16.3 0.4 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family Bunya_G2 PF03563.13 AAG06882.1 - 0.27 10.5 1.4 0.35 10.1 1.4 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 MtrF PF09472.10 AAG06882.1 - 3.1 7.3 5.9 0.61 9.5 1.6 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) HhH-GPD PF00730.25 AAG06883.1 - 1.8e-20 73.4 0.0 2.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAG06883.1 - 3.3e-10 39.3 0.0 7.6e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AAG06883.1 - 0.0002 21.6 4.4 0.00035 20.8 4.4 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III DUF4817 PF16087.5 AAG06883.1 - 0.014 15.1 0.0 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) HHH_5 PF14520.6 AAG06883.1 - 0.018 15.7 0.0 0.26 11.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_8 PF14716.6 AAG06883.1 - 0.11 12.8 0.0 0.56 10.6 0.0 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix domain RseC_MucC PF04246.12 AAG06883.1 - 4.2 7.3 4.6 67 3.4 1.7 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Fer2 PF00111.27 AAG06886.1 - 9.8e-12 44.7 3.8 1.5e-11 44.0 3.8 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AAG06886.1 - 8.4e-07 29.6 0.6 0.00022 21.9 0.1 2.8 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Fer2_3 PF13085.6 AAG06886.1 - 0.0037 17.2 0.1 0.0051 16.8 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAG06886.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 AAG06886.1 - 0.0071 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AAG06886.1 - 0.011 15.9 0.0 0.61 10.2 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Ribonuc_L-PSP PF01042.21 AAG06887.1 - 2.1e-14 53.6 0.0 2.6e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Rieske PF00355.26 AAG06888.1 - 7.2e-17 61.1 0.0 2.9e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Aromatic_hydrox PF11723.8 AAG06888.1 - 0.033 13.7 0.1 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Homotrimeric ring hydroxylase Rieske_2 PF13806.6 AAG06888.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Glyoxalase PF00903.25 AAG06891.1 - 1e-14 54.8 0.1 1.3e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG06891.1 - 0.0017 18.6 0.0 0.12 12.6 0.0 2.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Aldedh PF00171.22 AAG06892.1 - 3.5e-167 556.6 0.0 4e-167 556.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BRO1 PF03097.18 AAG06892.1 - 0.34 9.7 0.4 0.69 8.7 0.1 1.6 1 1 1 2 2 2 0 BRO1-like domain DUF108 PF01958.18 AAG06893.1 - 6.3e-33 113.0 0.0 9.7e-33 112.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 AAG06893.1 - 2.8e-25 89.2 0.0 4.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AAG06893.1 - 0.0016 18.7 0.0 0.0027 18.0 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 AAG06893.1 - 0.043 14.2 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAG06893.1 - 0.058 14.2 0.0 0.21 12.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 AAG06893.1 - 0.081 13.0 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TPP_enzyme_N PF02776.18 AAG06894.1 - 6.2e-44 149.6 3.0 6.2e-44 149.6 3.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAG06894.1 - 7.9e-30 103.7 0.2 2.8e-29 101.9 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG06894.1 - 3.7e-17 62.4 0.0 9.6e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain adh_short_C2 PF13561.6 AAG06895.1 - 3.4e-45 154.4 0.0 5.7e-45 153.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06895.1 - 5.2e-45 153.3 0.0 6.3e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG06895.1 - 1.6e-08 34.7 0.1 2.4e-08 34.1 0.1 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 AAG06895.1 - 7.9e-06 25.4 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AAG06895.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family IclR PF01614.18 AAG06896.1 - 6.5e-19 68.0 0.0 9.8e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AAG06896.1 - 1.8e-13 50.1 0.7 3.9e-13 49.0 0.7 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAG06896.1 - 2.2e-07 30.7 2.3 7.2e-07 29.0 0.0 2.7 3 0 0 3 3 3 1 MarR family MarR PF01047.22 AAG06896.1 - 6.4e-06 26.0 0.2 2.6e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AAG06896.1 - 7.4e-06 25.8 0.0 2.1e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AAG06896.1 - 0.00011 21.6 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAG06896.1 - 0.00091 19.2 0.1 0.0028 17.7 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAG06896.1 - 0.0039 17.0 0.0 0.0096 15.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AAG06896.1 - 0.0039 17.1 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 HTH domain DprA_WH PF17782.1 AAG06896.1 - 0.0055 16.8 0.1 0.047 13.8 0.0 2.4 2 0 0 2 2 2 1 DprA winged helix domain HTH_Crp_2 PF13545.6 AAG06896.1 - 0.0057 16.6 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_27 PF13463.6 AAG06896.1 - 0.0079 16.7 0.0 0.02 15.3 0.0 1.7 2 0 0 2 2 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 AAG06896.1 - 0.0089 16.4 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator DUF4423 PF14394.6 AAG06896.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Abhydrolase_6 PF12697.7 AAG06897.1 - 3.3e-22 80.2 6.3 4.2e-22 79.8 6.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG06897.1 - 7.1e-22 78.3 0.1 1.8e-19 70.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06897.1 - 6.8e-13 48.4 0.0 1.9e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 AAG06897.1 - 1.4e-06 28.3 0.1 0.0012 18.7 0.0 2.6 3 1 0 3 3 3 2 Serine hydrolase Thioesterase PF00975.20 AAG06897.1 - 0.0031 17.7 0.1 0.0043 17.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF3530 PF12048.8 AAG06897.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_3 PF07859.13 AAG06897.1 - 0.1 12.5 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 AAG06897.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydro_lipase PF04083.16 AAG06897.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Cupin_2 PF07883.11 AAG06898.1 - 8.6e-13 47.8 0.1 1.2e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AAG06898.1 - 1.1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Cupin FdtA PF05523.11 AAG06898.1 - 4.1e-05 23.3 0.0 5.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_3 PF05899.12 AAG06898.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GPI PF06560.11 AAG06898.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 1 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) adh_short_C2 PF13561.6 AAG06899.1 - 4.1e-62 209.8 0.1 4.7e-62 209.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG06899.1 - 4.1e-51 173.2 0.0 4.8e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG06899.1 - 1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 KR domain ATPgrasp_N PF18130.1 AAG06899.1 - 0.011 16.2 0.2 0.042 14.4 0.2 1.9 2 0 0 2 2 2 0 ATP-grasp N-terminal domain Epimerase PF01370.21 AAG06899.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 AAG06899.1 - 0.2 11.5 0.1 0.4 10.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BPD_transp_1 PF00528.22 AAG06900.1 - 4.3e-26 91.8 18.3 4.3e-26 91.8 18.3 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 AAG06900.1 - 6.1 7.3 8.7 1.2 9.6 0.2 2.9 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 NMT1 PF09084.11 AAG06901.1 - 5.6e-31 108.2 0.2 7.1e-31 107.8 0.2 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAG06901.1 - 8.8e-07 28.9 2.6 1.3e-06 28.3 2.6 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAG06901.1 - 0.0019 17.8 0.2 0.003 17.2 0.2 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein ABC_tran PF00005.27 AAG06902.1 - 7.8e-28 97.7 0.0 1.2e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG06902.1 - 2.6e-06 27.5 0.3 0.0058 16.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG06902.1 - 0.00035 20.1 0.2 0.19 11.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG06902.1 - 0.00056 20.3 1.8 0.0019 18.6 1.8 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG06902.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG06902.1 - 0.0016 18.7 0.1 0.0054 17.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAG06902.1 - 0.002 18.0 0.1 0.0036 17.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 AAG06902.1 - 0.017 13.9 0.4 0.59 8.9 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Rad17 PF03215.15 AAG06902.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain HD_3 PF13023.6 AAG06902.1 - 0.033 14.1 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 HD domain AAA PF00004.29 AAG06902.1 - 0.044 14.2 0.2 8.2 6.9 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AAG06902.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG06902.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 AAG06902.1 - 0.08 13.4 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAG06902.1 - 0.12 11.9 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein MMR_HSR1 PF01926.23 AAG06902.1 - 0.19 11.8 0.1 0.44 10.6 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 AAG06902.1 - 0.2 11.5 0.6 0.93 9.4 0.1 2.1 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 AAG06902.1 - 0.23 10.6 0.2 0.74 9.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 AAG06902.1 - 0.24 11.6 1.6 1.3 9.3 1.6 2.2 1 1 0 1 1 1 0 AAA domain Methyltransf_31 PF13847.6 AAG06903.1 - 1.1e-21 77.2 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG06903.1 - 8.3e-16 58.5 0.1 2e-15 57.2 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG06903.1 - 3.4e-14 53.4 0.0 9.7e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG06903.1 - 7.9e-14 51.8 0.0 2.7e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG06903.1 - 7.8e-13 48.9 0.1 1.6e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG06903.1 - 2.5e-11 43.4 0.0 3.8e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AAG06903.1 - 1.4e-08 34.5 0.0 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 AAG06903.1 - 3.2e-06 26.6 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 AAG06903.1 - 1.5e-05 24.4 0.0 2.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 AAG06903.1 - 1.7e-05 24.2 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 AAG06903.1 - 2.9e-05 23.8 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 AAG06903.1 - 4.9e-05 23.3 0.0 8.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AAG06903.1 - 0.00021 20.8 0.0 0.00041 19.9 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 AAG06903.1 - 0.00026 20.8 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 AAG06903.1 - 0.00094 19.0 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_15 PF09445.10 AAG06903.1 - 0.00098 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 AAG06903.1 - 0.0018 19.2 0.0 0.014 16.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 AAG06903.1 - 0.0047 16.1 0.1 0.017 14.3 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_32 PF13679.6 AAG06903.1 - 0.0096 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HTH_15 PF12324.8 AAG06903.1 - 0.0096 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of alkylmercury lyase GCD14 PF08704.10 AAG06903.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DREV PF05219.12 AAG06903.1 - 0.054 12.6 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase TehB PF03848.14 AAG06903.1 - 0.058 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB GidB PF02527.15 AAG06903.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Lyase_1 PF00206.20 AAG06904.1 - 2.7e-42 145.3 0.0 4.6e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AAG06904.1 - 1.3e-12 48.1 0.3 9.5e-12 45.3 0.0 2.6 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.20 AAG06905.1 - 1.1e-41 143.2 0.0 2.8e-41 141.9 0.0 1.6 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 AAG06905.1 - 5.2e-17 62.2 0.1 1.5e-16 60.7 0.1 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus HOASN PF14515.6 AAG06906.1 - 3.8e-51 171.5 3.0 3.8e-51 171.5 3.0 1.9 2 0 0 2 2 2 1 Haem-oxygenase-associated N-terminal helices Haem_oxygenas_2 PF14518.6 AAG06906.1 - 8.7e-14 51.7 1.2 2e-13 50.5 1.2 1.6 1 0 0 1 1 1 1 Iron-containing redox enzyme HOASN PF14515.6 AAG06907.1 - 8.6e-45 151.1 0.3 1.4e-44 150.4 0.3 1.4 1 0 0 1 1 1 1 Haem-oxygenase-associated N-terminal helices Haem_oxygenas_2 PF14518.6 AAG06907.1 - 8.8e-14 51.7 1.1 1.5e-13 50.9 1.1 1.4 1 0 0 1 1 1 1 Iron-containing redox enzyme HMA PF00403.26 AAG06908.1 - 3.3e-09 37.1 0.0 3.7e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain OEP PF02321.18 AAG06909.1 - 1e-39 136.3 24.7 4.1e-20 72.4 8.0 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein ACR_tran PF00873.19 AAG06910.1 - 0 1134.3 11.1 0 1134.1 11.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG06910.1 - 1.7e-15 56.8 42.5 1.3e-12 47.3 17.7 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAG06910.1 - 3.2e-05 23.4 9.2 3.2e-05 23.4 9.2 2.4 2 0 0 2 2 2 1 Protein export membrane protein Patched PF02460.18 AAG06910.1 - 0.092 10.8 10.2 0.19 9.8 10.2 1.4 1 0 0 1 1 1 0 Patched family LMBR1 PF04791.16 AAG06910.1 - 0.18 10.6 1.6 0.44 9.4 1.6 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein HlyD_D23 PF16576.5 AAG06911.1 - 4.2e-19 68.6 0.5 9.1e-19 67.5 0.5 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG06911.1 - 3.2e-11 42.9 1.1 2.9e-07 30.2 0.1 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AAG06911.1 - 1.3e-08 35.5 0.9 3.5e-05 24.4 0.1 3.0 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AAG06911.1 - 0.00097 18.9 0.1 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme RsmF_methylt_CI PF17126.5 AAG06911.1 - 0.036 14.1 0.1 0.35 10.9 0.1 2.2 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain Glyoxalase PF00903.25 AAG06912.1 - 8.4e-23 81.0 0.2 9.8e-23 80.8 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG06912.1 - 1.2e-09 38.4 0.0 7.8e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG06912.1 - 3.2e-05 24.7 0.0 5.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 AAG06912.1 - 0.14 12.3 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Arginosuc_synth PF00764.19 AAG06913.1 - 7.7e-155 515.9 0.0 8.9e-155 515.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 AAG06913.1 - 0.0014 18.2 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AAG06913.1 - 0.0022 17.7 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase MotY_N PF18393.1 AAG06914.1 - 6e-45 152.9 0.0 9.1e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 MotY N-terminal domain OmpA PF00691.20 AAG06914.1 - 7e-19 68.0 0.1 1.1e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 OmpA family Amidohydro_1 PF01979.20 AAG06915.1 - 5.9e-14 52.1 0.2 9.9e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 AAG06915.1 - 4.8e-05 23.3 0.5 7.3e-05 22.7 0.5 1.3 1 0 0 1 1 1 1 Amidohydrolase ComA PF02679.15 AAG06915.1 - 0.0031 17.0 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) RNase_T PF00929.24 AAG06916.1 - 1.4e-32 113.5 0.0 1.7e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAG06916.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like CAF1 PF04857.20 AAG06916.1 - 0.049 12.8 0.1 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 CAF1 family ribonuclease AhpC-TSA PF00578.21 AAG06917.1 - 3.1e-33 114.3 0.0 4.2e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAG06917.1 - 7.6e-17 61.4 0.0 9.4e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AAG06917.1 - 1.4e-14 53.7 0.1 3.1e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_8 PF13905.6 AAG06917.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Fer2_BFD PF04324.15 AAG06918.1 - 9.8e-12 45.0 8.3 1.2e-11 44.7 8.3 1.2 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Ferritin PF00210.24 AAG06919.1 - 4.7e-40 136.8 5.1 5.8e-40 136.5 5.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF1241 PF06840.11 AAG06919.1 - 0.00015 21.5 0.2 0.00024 20.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) FPV060 PF17614.2 AAG06919.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Viral CC-type chemokine MFS_1 PF07690.16 AAG06920.1 - 6.1e-22 78.0 48.1 5e-18 65.1 39.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAG06920.1 - 0.87 8.4 8.0 1.1 8.1 7.1 1.7 2 0 0 2 2 2 0 MFS_1 like family MFS_4 PF06779.14 AAG06920.1 - 1.3 8.2 26.9 1.2 8.3 25.9 1.4 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 AAG06920.1 - 7.2 4.9 23.4 0.092 11.1 6.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF3021 PF11457.8 AAG06920.1 - 8.8 6.7 9.8 1.2 9.5 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Glutaredoxin PF00462.24 AAG06921.1 - 1.2e-18 67.1 0.0 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AAG06921.1 - 0.031 14.7 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG06921.1 - 0.093 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Molybdopterin PF00384.22 AAG06922.1 - 1e-35 123.5 0.0 1.9e-35 122.7 0.0 1.4 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAG06922.1 - 4e-26 91.2 0.3 1.1e-25 89.8 0.0 1.8 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAG06922.1 - 1.2e-05 25.1 0.1 2.8e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Autotransporter PF03797.19 AAG06923.1 - 5e-56 190.2 15.2 5e-56 190.2 15.2 3.5 3 1 0 4 4 4 1 Autotransporter beta-domain Peptidase_S8 PF00082.22 AAG06923.1 - 2.8e-38 131.9 6.2 4.2e-38 131.3 6.2 1.3 1 0 0 1 1 1 1 Subtilase family PATR PF12951.7 AAG06923.1 - 1.3e-08 34.8 0.5 7.7e-08 32.3 0.2 2.7 2 0 0 2 2 2 1 Passenger-associated-transport-repeat NrsF PF06532.11 AAG06924.1 - 0.0044 16.8 16.7 0.005 16.6 16.7 1.1 1 0 0 1 1 1 1 Negative regulator of sigma F ABC2_membrane_2 PF12679.7 AAG06924.1 - 0.94 8.7 12.1 0.99 8.6 10.8 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2631 PF10939.8 AAG06924.1 - 1.3 8.9 3.7 4.9 7.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) OTCace PF00185.24 AAG06925.1 - 6.7e-50 169.2 0.0 8.9e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AAG06925.1 - 5.1e-46 156.4 0.0 6.9e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ABC_tran PF00005.27 AAG06926.1 - 2.9e-30 105.6 0.0 4.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAG06926.1 - 9.2e-11 41.8 0.4 1.9e-10 40.7 0.1 1.8 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AAG06926.1 - 1e-09 38.7 2.2 1.1e-05 25.4 0.8 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG06926.1 - 0.00028 20.4 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG06926.1 - 0.00073 19.8 0.6 0.0039 17.5 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAG06926.1 - 0.0044 17.4 0.1 0.011 16.2 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAG06926.1 - 0.0069 16.5 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 AAG06926.1 - 0.018 15.3 0.1 0.16 12.2 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AAG06926.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 AAG06926.1 - 0.031 14.2 0.0 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 AAG06926.1 - 0.031 14.5 0.1 0.083 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAG06926.1 - 0.046 14.2 0.0 0.074 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAG06926.1 - 0.067 13.6 3.6 0.79 10.1 3.6 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 AAG06926.1 - 0.21 11.4 0.1 0.41 10.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AAG06926.1 - 0.35 10.8 1.4 1 9.3 0.2 2.1 2 0 0 2 2 2 0 NACHT domain H2O2_YaaD PF03883.14 AAG06927.1 - 5.8e-90 300.9 0.1 6.5e-90 300.7 0.1 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA PHB_acc PF05233.13 AAG06927.1 - 0.12 12.4 0.8 0.75 9.9 0.0 2.2 2 0 0 2 2 2 0 PHB accumulation regulatory domain Glyco_hydro_76 PF03663.14 AAG06927.1 - 0.15 11.6 0.4 0.56 9.7 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 UDPG_MGDP_dh_N PF03721.14 AAG06928.1 - 3.7e-66 222.3 0.1 1.1e-65 220.7 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAG06928.1 - 1.3e-28 99.1 0.0 2.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAG06928.1 - 5.3e-13 49.3 0.0 2.5e-12 47.2 0.0 2.1 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 AAG06928.1 - 0.0053 16.4 0.1 0.0098 15.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AAG06928.1 - 0.01 16.0 0.0 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAG06928.1 - 0.016 14.6 0.2 0.27 10.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAG06928.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAG06928.1 - 0.021 14.8 0.0 9.6 6.2 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 AAG06928.1 - 0.14 12.0 0.3 22 4.9 0.1 2.4 2 0 0 2 2 2 0 Rossmann-like domain Glyco_tranf_2_3 PF13641.6 AAG06929.1 - 4.5e-54 183.8 0.1 6.9e-54 183.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAG06929.1 - 5.2e-34 117.9 3.3 5.2e-34 117.9 3.3 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 PilZ PF07238.14 AAG06930.1 - 5.7e-14 52.3 0.0 2.2e-11 44.0 0.0 2.9 3 0 0 3 3 3 1 PilZ domain HlyD_3 PF13437.6 AAG06930.1 - 6.2e-11 43.0 0.5 2.7e-10 40.9 0.1 2.3 3 0 0 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG06930.1 - 3.3e-07 30.0 0.1 2.1e-05 24.3 0.0 3.5 4 1 0 4 4 4 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG06930.1 - 0.00038 19.7 0.0 0.0017 17.6 0.0 2.0 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AAG06930.1 - 0.077 12.8 0.0 8.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Biotin-requiring enzyme Sel1 PF08238.12 AAG06931.1 - 2.2e-06 28.2 23.1 0.00021 21.9 0.3 6.4 6 0 0 6 6 6 2 Sel1 repeat TPR_17 PF13431.6 AAG06931.1 - 0.013 15.8 5.5 12 6.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAG06931.1 - 4.8 8.3 41.9 4.3 8.4 0.1 8.6 4 2 5 9 9 9 0 Tetratricopeptide repeat Alginate_exp PF13372.6 AAG06932.1 - 1.3e-120 402.8 14.8 1.5e-120 402.6 14.8 1.0 1 0 0 1 1 1 1 Alginate export Beta_helix PF13229.6 AAG06933.1 - 6.1e-19 68.4 17.0 1e-11 44.9 1.3 2.2 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 AAG06933.1 - 3.8e-16 59.1 6.2 6.4e-16 58.3 6.2 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) ALGX PF16822.5 AAG06934.1 - 1.7e-84 283.7 0.0 2.3e-84 283.3 0.0 1.2 1 0 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX CBM_26 PF16824.5 AAG06934.1 - 1.6e-57 193.3 0.0 2.4e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal carbohydrate-binding module Alginate_lyase PF05426.12 AAG06935.1 - 6.3e-59 199.7 4.8 7.8e-59 199.5 4.8 1.1 1 0 0 1 1 1 1 Alginate lyase MBOAT PF03062.19 AAG06936.1 - 8.2e-28 97.8 13.6 4.7e-27 95.3 12.2 2.5 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AAG06936.1 - 0.0055 16.9 5.6 0.016 15.5 5.6 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ALGX PF16822.5 AAG06937.1 - 6.5e-100 334.2 0.1 7.8e-100 334.0 0.1 1.1 1 0 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX AlgF PF11182.8 AAG06938.1 - 1.4e-85 285.6 0.1 1.7e-85 285.4 0.1 1.0 1 0 0 1 1 1 1 Alginate O-acetyl transferase AlgF LTD PF00932.19 AAG06938.1 - 0.0034 17.7 0.0 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 Lamin Tail Domain DUF4397 PF14344.6 AAG06938.1 - 0.03 15.1 0.0 0.14 12.9 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4397) Myosin_N PF02736.19 AAG06938.1 - 0.048 13.5 0.3 0.12 12.3 0.3 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain VWA PF00092.28 AAG06938.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain NTP_transferase PF00483.23 AAG06939.1 - 4.6e-77 259.0 0.0 6.4e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 AAG06939.1 - 4.7e-77 257.0 1.0 7.2e-77 256.4 1.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_2 PF07883.11 AAG06939.1 - 1.1e-10 41.0 0.2 2.7e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Cupin domain NTP_transf_3 PF12804.7 AAG06939.1 - 4.6e-07 30.3 0.1 9.8e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain AraC_binding PF02311.19 AAG06939.1 - 0.0045 16.9 0.0 0.0096 15.8 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain CENP-C_C PF11699.8 AAG06939.1 - 0.2 11.9 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like DegT_DnrJ_EryC1 PF01041.17 AAG06940.1 - 2.7e-124 415.2 0.0 3e-124 415.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AAG06940.1 - 1e-10 41.4 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAG06940.1 - 5e-05 22.4 0.0 7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAG06940.1 - 6.4e-05 21.7 0.0 9.1e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PaRep2b PF07775.11 AAG06940.1 - 0.13 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 PaRep2b protein Glycos_transf_2 PF00535.26 AAG06941.1 - 2.8e-32 111.9 0.0 4.1e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAG06941.1 - 1.8e-13 50.9 0.1 5e-13 49.5 0.1 1.7 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAG06941.1 - 2e-05 24.2 0.0 2.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAG06941.1 - 0.0011 19.5 0.0 0.0023 18.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAG06941.1 - 0.019 14.5 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Epimerase PF01370.21 AAG06942.1 - 6.3e-44 150.2 0.0 1e-43 149.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Formyl_trans_N PF00551.19 AAG06942.1 - 4e-26 91.9 0.0 5.8e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase GDP_Man_Dehyd PF16363.5 AAG06942.1 - 1.4e-24 87.1 0.0 2e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Formyl_trans_C PF02911.18 AAG06942.1 - 5e-16 58.8 0.0 1.4e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain 3Beta_HSD PF01073.19 AAG06942.1 - 0.00033 19.8 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAG06942.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AAG06942.1 - 0.015 14.5 0.0 0.84 8.8 0.0 2.2 1 1 0 1 1 1 0 Male sterility protein Polysacc_deac_1 PF01522.21 AAG06943.1 - 7.6e-14 51.7 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 AAG06943.1 - 0.063 12.9 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) PMT PF02366.18 AAG06944.1 - 2.4e-30 105.9 16.8 4e-30 105.2 13.9 2.4 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 AAG06944.1 - 5.4e-19 69.0 14.0 5.4e-19 69.0 14.0 2.7 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glucos_trans_II PF14264.6 AAG06944.1 - 0.0081 15.5 12.6 0.014 14.8 8.0 2.7 1 1 1 2 2 2 1 Glucosyl transferase GtrII EamA PF00892.20 AAG06945.1 - 1.7e-09 38.0 5.4 6e-09 36.2 5.4 1.8 1 1 0 1 1 1 1 EamA-like transporter family Multi_Drug_Res PF00893.19 AAG06945.1 - 9.5e-05 23.0 0.2 0.00015 22.4 0.1 1.4 1 1 0 1 1 1 1 Small Multidrug Resistance protein TMEM234 PF10639.9 AAG06945.1 - 0.00086 19.3 0.0 0.00089 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF5317 PF17248.2 AAG06945.1 - 0.047 13.7 0.6 0.079 13.0 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5317) DUF202 PF02656.15 AAG06945.1 - 0.55 10.7 8.8 2.4 8.7 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Multi_Drug_Res PF00893.19 AAG06946.1 - 9.6e-07 29.4 2.3 1.3e-06 29.0 2.3 1.3 1 1 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAG06946.1 - 0.00076 19.7 10.2 0.0035 17.5 10.5 1.7 1 1 0 1 1 1 1 EamA-like transporter family SLATT_1 PF18181.1 AAG06946.1 - 0.035 14.0 2.2 0.057 13.3 1.5 1.8 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2569 PF10754.9 AAG06946.1 - 0.13 12.7 2.2 0.16 12.4 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) UDPG_MGDP_dh_N PF03721.14 AAG06947.1 - 1.3e-59 201.0 0.0 1.8e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAG06947.1 - 1.8e-36 124.2 0.0 4e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAG06947.1 - 8.2e-32 109.8 0.0 1.9e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 AAG06947.1 - 0.00027 20.9 0.1 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AAG06947.1 - 0.011 15.4 0.0 0.042 13.5 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF2795 PF11387.8 AAG06947.1 - 0.027 14.7 0.3 0.19 11.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) Pyr_redox PF00070.27 AAG06947.1 - 0.03 14.9 0.6 0.43 11.2 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG06947.1 - 0.089 13.0 0.0 0.73 10.1 0.1 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 AAG06947.1 - 0.096 12.9 0.0 3 8.0 0.0 3.0 4 0 0 4 4 4 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 AAG06947.1 - 0.13 12.6 0.0 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain AlaDh_PNT_C PF01262.21 AAG06947.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AAG06947.1 - 0.16 11.2 0.3 0.46 9.7 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 AAG06947.1 - 0.16 12.4 0.0 7.5 7.0 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 AAG06947.1 - 0.21 11.6 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PTS_IIB PF02302.17 AAG06948.1 - 2.2e-31 108.4 0.0 1.2e-17 64.3 0.2 2.7 2 1 1 3 3 3 2 PTS system, Lactose/Cellobiose specific IIB subunit PTS_EIIC PF02378.18 AAG06948.1 - 2.9e-18 66.0 32.2 5.7e-18 65.0 26.5 3.4 3 1 0 3 3 3 1 Phosphotransferase system, EIIC PfkB PF00294.24 AAG06949.1 - 3.6e-42 144.7 0.0 4.2e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AAG06949.1 - 2.6e-05 23.8 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PEP-utilizers_C PF02896.18 AAG06950.1 - 1.2e-102 343.0 0.0 1.8e-102 342.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PTS_EIIA_2 PF00359.22 AAG06950.1 - 7.2e-34 116.8 0.0 1.1e-26 93.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PEP-utilizers PF00391.23 AAG06950.1 - 3.2e-22 78.0 0.5 8.7e-22 76.6 0.5 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PEP-utilisers_N PF05524.13 AAG06950.1 - 9.5e-21 74.1 4.3 9.5e-21 74.1 4.3 2.3 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal PTS-HPr PF00381.19 AAG06950.1 - 4.5e-19 68.5 0.3 1.5e-18 66.8 0.3 2.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site Peripla_BP_1 PF00532.21 AAG06951.1 - 1.4e-20 73.9 0.0 1.7e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AAG06951.1 - 3.4e-19 68.4 0.7 3.6e-18 65.1 0.6 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AAG06951.1 - 6.7e-14 52.1 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_3 PF13377.6 AAG06951.1 - 2.9e-09 37.5 2.6 8.3e-08 32.7 0.2 2.4 1 1 1 2 2 2 1 Periplasmic binding protein-like domain HTH_3 PF01381.22 AAG06951.1 - 0.028 14.5 0.1 0.061 13.4 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_IclR PF09339.10 AAG06951.1 - 2.7 7.9 5.7 3.3 7.6 0.0 3.3 4 0 0 4 4 4 0 IclR helix-turn-helix domain TatD_DNase PF01026.21 AAG06952.1 - 2.1e-57 194.4 0.0 2.3e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 AAG06952.1 - 0.0067 16.2 1.1 0.074 12.8 0.1 2.1 1 1 1 2 2 2 1 Amidohydrolase NapD PF03927.13 AAG06952.1 - 0.085 12.9 0.0 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 NapD protein LysR_substrate PF03466.20 AAG06953.1 - 4e-43 147.2 7.8 4e-43 147.2 7.8 1.9 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06953.1 - 4.5e-19 68.1 2.4 2.4e-18 65.8 0.3 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family ABM PF03992.16 AAG06954.1 - 1.1e-23 83.1 0.1 1.3e-23 82.9 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ADH_zinc_N_2 PF13602.6 AAG06955.1 - 1.5e-23 84.3 0.3 2.8e-23 83.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AAG06955.1 - 3.9e-12 46.3 0.0 7.9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG06955.1 - 1.8e-06 27.8 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 AAG06955.1 - 0.032 13.7 0.4 0.045 13.2 0.4 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 AAG06955.1 - 0.056 13.6 0.1 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 AAG06955.1 - 0.099 12.9 0.1 0.64 10.3 0.1 2.1 1 1 0 1 1 1 0 TrkA-N domain AMP-binding PF00501.28 AAG06956.1 - 4.4e-85 285.8 0.0 5.3e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG06956.1 - 5.3e-25 88.2 1.7 1.1e-24 87.2 1.7 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAG06956.1 - 2.1e-13 50.0 0.1 3.6e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus NAD_binding_2 PF03446.15 AAG06957.1 - 2.6e-51 173.9 0.3 4.8e-51 173.1 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAG06957.1 - 4.9e-36 123.6 0.3 1e-35 122.6 0.3 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AAG06957.1 - 7.9e-06 26.4 0.0 2.8e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AAG06957.1 - 0.0014 18.5 0.1 0.0029 17.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAG06957.1 - 0.026 14.1 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 AAG06957.1 - 0.031 13.9 0.2 0.07 12.8 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cecropin PF00272.19 AAG06957.1 - 0.19 11.5 1.6 0.66 9.7 0.0 2.7 2 0 0 2 2 2 0 Cecropin family Aldedh PF00171.22 AAG06958.1 - 1.1e-136 456.0 0.0 1.2e-136 455.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAG06958.1 - 0.0018 17.4 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Wtap PF17098.5 AAG06958.1 - 0.047 13.6 0.1 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family AraC_binding PF02311.19 AAG06959.1 - 2.6e-28 98.6 6.4 4.3e-28 97.9 6.4 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_AraC PF00165.23 AAG06959.1 - 4.3e-22 77.7 0.3 4.3e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 AAG06959.1 - 4.3e-16 59.0 0.1 1e-15 57.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 AAG06959.1 - 3.7e-07 29.8 0.1 6.9e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 AAG06959.1 - 4.2e-05 23.8 0.0 7.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_4 PF08007.12 AAG06959.1 - 0.024 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 AAG06959.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Cupin PknH_C PF14032.6 AAG06960.1 - 0.0023 17.8 0.0 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 PknH-like extracellular domain SPOR PF05036.13 AAG06960.1 - 0.09 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Sporulation related domain MFS_1 PF07690.16 AAG06961.1 - 6e-37 127.4 40.7 6e-37 127.4 40.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG06961.1 - 1e-08 34.5 6.3 1e-08 34.5 6.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AAG06961.1 - 1.9e-05 24.1 9.2 1.9e-05 24.1 9.2 2.1 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Mononeg_RNA_pol PF00946.19 AAG06961.1 - 0.12 10.0 0.0 0.15 9.7 0.0 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase TMEM82 PF15816.5 AAG06961.1 - 1.2 8.1 6.3 0.22 10.5 1.9 2.0 2 0 0 2 2 2 0 Transmembrane protein 82 TetR_N PF00440.23 AAG06962.1 - 5.1e-18 64.6 0.1 9.7e-18 63.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_2 PF08361.11 AAG06962.1 - 2.7e-13 50.1 0.0 4.4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 MAATS-type transcriptional repressor, C-terminal region TetR_C_6 PF13977.6 AAG06962.1 - 0.0012 19.1 0.2 0.0026 18.0 0.2 1.7 1 1 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal HTH_Tnp_1_2 PF13022.6 AAG06962.1 - 0.027 14.6 0.4 0.21 11.8 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix of insertion element transposase UPF0122 PF04297.14 AAG06962.1 - 0.077 13.2 0.2 5.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like LacI PF00356.21 AAG06962.1 - 0.14 11.9 0.0 8.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Ni_hydr_CYTB PF01292.20 AAG06963.1 - 1.1e-26 93.6 7.5 1.2e-26 93.4 7.5 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Sec_GG PF07549.14 AAG06963.1 - 0.11 12.0 0.2 0.29 10.7 0.2 1.8 1 0 0 1 1 1 0 SecD/SecF GG Motif Cytochrom_B561 PF03188.16 AAG06963.1 - 0.15 12.2 5.3 0.2 11.8 1.6 2.4 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 Fil_haemagg PF05594.14 AAG06964.1 - 0.095 13.3 0.2 0.14 12.7 0.2 1.3 1 0 0 1 1 1 0 Haemagluttinin repeat DUF2846 PF11008.8 AAG06964.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) PhzC-PhzF PF02567.16 AAG06966.1 - 2.7e-62 210.8 0.0 3.5e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein FGGY_N PF00370.21 AAG06967.1 - 1.3e-73 247.6 0.0 1.9e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AAG06967.1 - 2.9e-56 190.3 0.3 5.7e-56 189.4 0.3 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain tRNA_edit PF04073.15 AAG06968.1 - 4.5e-26 91.3 0.1 5.2e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain MIP PF00230.20 AAG06969.1 - 8.7e-66 221.9 12.4 1e-65 221.6 12.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein FGGY_N PF00370.21 AAG06970.1 - 6.7e-88 294.4 0.1 9.3e-88 293.9 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AAG06970.1 - 1.9e-62 210.6 0.1 6.2e-62 208.8 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DeoRC PF00455.22 AAG06971.1 - 2.4e-53 180.4 0.6 3.1e-53 180.0 0.6 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AAG06971.1 - 2.5e-21 75.2 0.8 5.4e-21 74.1 0.1 1.9 2 1 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAG06971.1 - 2.1e-08 34.0 0.2 4.3e-08 33.0 0.2 1.5 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 AAG06971.1 - 5e-06 26.1 0.1 1.2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAG06971.1 - 5.9e-06 26.2 0.4 9.9e-05 22.2 0.1 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAG06971.1 - 7.5e-05 22.5 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAG06971.1 - 0.00011 22.1 0.1 0.00037 20.4 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 AAG06971.1 - 0.00047 19.7 0.0 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAG06971.1 - 0.00099 19.1 0.1 0.0051 16.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAG06971.1 - 0.0013 18.2 0.1 0.0034 16.9 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 AAG06971.1 - 0.0044 17.1 0.6 0.011 15.8 0.2 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAG06971.1 - 0.0056 16.3 0.1 0.058 13.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 AAG06971.1 - 0.0062 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix Put_DNA-bind_N PF06971.13 AAG06971.1 - 0.0075 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus Rrf2 PF02082.20 AAG06971.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Cullin_Nedd8 PF10557.9 AAG06971.1 - 0.014 15.4 0.3 0.066 13.3 0.1 2.3 2 1 0 2 2 2 0 Cullin protein neddylation domain LexA_DNA_bind PF01726.16 AAG06971.1 - 0.016 15.0 0.1 0.045 13.5 0.1 1.8 2 0 0 2 2 2 0 LexA DNA binding domain HTH_38 PF13936.6 AAG06971.1 - 0.021 14.6 0.5 0.18 11.6 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain DDRGK PF09756.9 AAG06971.1 - 0.024 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 DDRGK domain HTH_40 PF14493.6 AAG06971.1 - 0.034 14.6 0.5 1 9.9 0.0 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 AAG06971.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 AAG06971.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 MerR family regulatory protein HTH_Tnp_ISL3 PF13542.6 AAG06971.1 - 0.14 11.6 0.2 0.87 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DAO PF01266.24 AAG06972.1 - 3.7e-49 168.2 0.5 3.7e-49 168.2 0.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 AAG06972.1 - 9.2e-14 51.4 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 AAG06972.1 - 0.00021 20.7 0.1 0.0056 16.1 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAG06972.1 - 0.007 15.6 0.2 0.046 13.0 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAG06972.1 - 0.009 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AAG06972.1 - 0.067 13.8 0.1 0.5 11.0 0.2 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG06972.1 - 0.13 11.3 1.5 0.19 10.8 1.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAG06972.1 - 0.24 11.6 1.5 0.75 10.1 0.4 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAG06972.1 - 0.32 10.0 8.0 0.046 12.8 1.8 2.3 3 0 0 3 3 3 0 FAD binding domain GlpM PF06942.12 AAG06973.1 - 1e-49 167.4 9.4 1.1e-49 167.2 9.4 1.0 1 0 0 1 1 1 1 GlpM protein DUF3147 PF11345.8 AAG06973.1 - 0.02 15.3 6.8 0.03 14.7 6.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3147) DUF5518 PF17647.1 AAG06973.1 - 0.074 13.2 8.6 0.095 12.9 8.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Abhydrolase_1 PF00561.20 AAG06974.1 - 2.9e-19 69.7 0.0 4e-18 66.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG06974.1 - 1.5e-12 47.3 0.3 4.4e-12 45.8 0.3 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAG06974.1 - 4.1e-11 43.9 7.5 5.7e-11 43.4 7.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 AAG06974.1 - 0.00045 20.2 1.2 0.0014 18.5 1.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAG06974.1 - 0.0061 16.1 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AAG06974.1 - 0.035 13.9 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LysR_substrate PF03466.20 AAG06975.1 - 3e-37 128.0 1.3 4.3e-37 127.5 1.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06975.1 - 4.8e-18 64.9 2.0 9.3e-18 63.9 2.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAG06975.1 - 0.0016 18.5 1.5 0.006 16.6 1.5 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG06975.1 - 0.01 15.7 1.7 0.026 14.4 0.7 2.3 2 0 0 2 2 2 1 MarR family HTH_30 PF13556.6 AAG06975.1 - 0.074 12.9 0.8 0.19 11.6 0.8 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 AAG06975.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_5 PF01022.20 AAG06975.1 - 0.19 11.6 2.7 0.33 10.8 1.6 2.0 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family OprD PF03573.13 AAG06976.1 - 1.3e-146 488.7 0.8 1.5e-146 488.5 0.8 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Thiolase_N PF00108.23 AAG06977.1 - 2.3e-61 207.5 0.0 4.4e-61 206.5 0.0 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG06977.1 - 8.3e-43 144.9 0.1 1.5e-42 144.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG06977.1 - 0.0024 17.5 0.3 0.0072 15.9 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain 3HCDH_N PF02737.18 AAG06978.1 - 3.7e-57 193.1 0.2 6.4e-57 192.3 0.1 1.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AAG06978.1 - 5.1e-57 190.5 0.0 6.8e-32 110.0 0.0 3.1 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 AAG06978.1 - 0.00071 19.0 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAG06978.1 - 0.00098 19.3 0.1 0.0017 18.5 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.6 AAG06978.1 - 0.022 15.0 2.4 0.03 14.5 0.8 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 AAG06978.1 - 0.023 15.2 0.2 0.064 13.8 0.2 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 AAG06978.1 - 0.033 14.7 0.5 0.077 13.6 0.5 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TRAF_BIRC3_bd PF16673.5 AAG06978.1 - 0.17 11.7 2.0 0.19 11.5 0.4 1.8 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain ECH_1 PF00378.20 AAG06979.1 - 4.5e-69 232.6 0.2 5e-69 232.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG06979.1 - 7.3e-33 114.5 1.3 5e-29 101.9 0.7 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CoA_transf_3 PF02515.17 AAG06980.1 - 7.1e-122 407.1 0.0 8.1e-122 406.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III AbiEi_4 PF13338.6 AAG06980.1 - 0.051 13.7 0.2 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Acyl-CoA_dh_1 PF00441.24 AAG06981.1 - 3.2e-35 121.5 2.0 6.7e-35 120.5 2.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 AAG06981.1 - 2.9e-20 72.8 0.0 8.5e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG06981.1 - 1.8e-16 60.1 0.0 3.3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG06981.1 - 2.1e-07 31.3 0.1 2.1e-07 31.3 0.1 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG06981.1 - 0.058 14.0 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain LysR_substrate PF03466.20 AAG06982.1 - 1.4e-45 155.2 4.2 1.8e-45 154.9 4.2 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG06982.1 - 6.3e-21 74.1 0.4 1.3e-20 73.1 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SBP_bac_11 PF13531.6 AAG06982.1 - 0.03 14.1 0.1 2.4 7.9 0.0 2.5 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein DUF4404 PF14357.6 AAG06982.1 - 0.039 14.6 0.3 0.16 12.6 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) PBP_like_2 PF12849.7 AAG06982.1 - 0.096 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain Sugar_tr PF00083.24 AAG06983.1 - 9.8e-20 70.8 30.7 1.3e-17 63.8 10.1 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAG06983.1 - 2.6e-18 66.1 49.1 1.4e-13 50.5 22.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily VanZ PF04892.12 AAG06983.1 - 0.79 10.4 5.6 2.4 8.9 4.6 2.4 1 1 0 1 1 1 0 VanZ like family DNA_binding_1 PF01035.20 AAG06984.1 - 4.3e-30 103.7 0.3 9e-30 102.6 0.1 1.7 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.16 AAG06984.1 - 1.6e-27 95.3 1.6 3.2e-27 94.3 1.6 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 AAG06984.1 - 1.4e-15 57.3 0.4 3.5e-15 56.0 0.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG06984.1 - 1.2e-05 25.3 0.1 0.00066 19.7 0.0 3.2 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix proteins, AraC family AA_permease PF00324.21 AAG06985.1 - 1.8e-38 132.4 26.2 2.3e-38 132.0 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG06985.1 - 1.8e-37 129.2 32.1 2.3e-37 128.8 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 AAG06985.1 - 0.0085 16.1 4.7 0.011 15.8 0.9 3.2 2 0 0 2 2 2 1 C-terminus of AA_permease CN_hydrolase PF00795.22 AAG06986.1 - 4.4e-49 167.2 0.0 5e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_4 PF08386.10 AAG06986.1 - 0.0046 17.0 0.0 0.0072 16.4 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein GerE PF00196.19 AAG06987.1 - 6.4e-17 60.8 0.0 1.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG06987.1 - 0.00021 20.9 0.1 0.00078 19.1 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG06987.1 - 0.01 15.3 0.2 0.16 11.5 0.1 2.5 1 1 1 2 2 2 0 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG06987.1 - 0.051 13.5 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor HTH_24 PF13412.6 AAG06987.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ribosomal_L36 PF00444.18 AAG06988.1 - 1.3e-15 57.3 6.0 1.3e-15 57.3 6.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L36 DUF2452 PF10504.9 AAG06988.1 - 0.18 11.3 0.1 0.18 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Ribosomal_L31 PF01197.18 AAG06989.1 - 4.8e-25 87.6 0.3 5.6e-25 87.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31 Glu_synthase PF01645.17 AAG06990.1 - 3.8e-82 276.4 0.0 4.8e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 AAG06990.1 - 0.049 12.7 0.1 0.083 11.9 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DAGK_prokar PF01219.19 AAG06991.1 - 2.7e-32 110.6 2.7 3.2e-32 110.4 2.7 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase Response_reg PF00072.24 AAG06992.1 - 5.3e-22 78.1 0.0 8.6e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG06992.1 - 2.7e-19 68.4 0.1 4.1e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG06992.1 - 1.2e-07 31.3 0.0 3.9e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAG06992.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AAG06992.1 - 0.0026 17.2 0.0 0.0069 15.9 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG06992.1 - 0.036 13.9 0.7 0.29 11.0 0.0 2.7 4 0 0 4 4 4 0 Homeodomain-like domain HTH_40 PF14493.6 AAG06992.1 - 0.069 13.6 0.0 0.39 11.2 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2089 PF09862.9 AAG06992.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_6 PF01418.17 AAG06992.1 - 0.15 12.0 0.5 27 4.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family Transglut_i_TM PF14400.6 AAG06992.1 - 0.18 11.8 0.9 1.9 8.5 0.0 2.4 3 0 0 3 3 3 0 Inactive transglutaminase fused to 7 transmembrane helices HTH_7 PF02796.15 AAG06992.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase EamA PF00892.20 AAG06993.1 - 1.3e-35 122.5 32.1 7.9e-18 64.9 12.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 AAG06993.1 - 0.0074 15.4 2.9 0.0074 15.4 2.9 1.9 2 0 0 2 2 2 1 Magnesium transporter NIPA TPT PF03151.16 AAG06993.1 - 0.18 11.1 4.1 0.15 11.4 0.5 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DTW PF03942.15 AAG06994.1 - 1.5e-42 145.6 0.0 1.7e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 DTW domain ABC_tran PF00005.27 AAG06995.1 - 5.4e-37 127.4 0.0 8.4e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAG06995.1 - 2.2e-16 59.8 0.1 8.7e-16 57.9 0.1 2.1 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AAG06995.1 - 3.7e-07 30.3 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAG06995.1 - 0.00054 20.3 0.2 0.0021 18.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG06995.1 - 0.0023 18.3 0.2 0.0061 17.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG06995.1 - 0.0035 17.3 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase OB_aCoA_assoc PF01796.17 AAG06995.1 - 0.0063 16.5 0.6 0.46 10.5 0.0 3.3 3 0 0 3 3 3 1 DUF35 OB-fold domain, acyl-CoA-associated Rad17 PF03215.15 AAG06995.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 AAG06995.1 - 0.014 15.9 0.0 0.028 14.8 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAG06995.1 - 0.019 14.7 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 AAG06995.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAG06995.1 - 0.063 13.3 0.0 0.34 10.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AAG06995.1 - 0.078 12.5 0.4 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAG06995.1 - 0.08 13.4 0.2 0.14 12.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAG06995.1 - 0.085 12.8 0.1 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 AAG06995.1 - 0.1 12.8 0.2 0.76 10.0 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit BPD_transp_1 PF00528.22 AAG06996.1 - 1.1e-14 54.7 15.1 1.1e-14 54.7 15.1 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4658 PF15555.6 AAG06996.1 - 0.016 15.4 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) BPD_transp_1 PF00528.22 AAG06997.1 - 1.7e-18 67.1 20.7 1.7e-18 67.1 20.7 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SID-1_RNA_chan PF13965.6 AAG06997.1 - 0.94 7.8 4.0 1.4 7.3 4.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SBP_bac_8 PF13416.6 AAG06998.1 - 5.1e-30 105.3 0.8 6.5e-30 104.9 0.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG06998.1 - 3.3e-27 95.5 0.2 4.9e-27 94.9 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG06998.1 - 1.4e-13 51.5 2.3 2.4e-13 50.7 2.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein QSregVF PF13652.6 AAG06999.1 - 3.1e-64 214.0 0.1 3.6e-64 213.8 0.1 1.0 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor QSregVF_b PF12843.7 AAG07000.1 - 3.7e-31 106.8 2.0 4.1e-31 106.7 2.0 1.0 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor XFP PF03894.15 AAG07001.1 - 1.8e-42 145.0 0.0 2.8e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_N PF09364.10 AAG07001.1 - 2.1e-14 53.1 0.0 3.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain Beta-Casp PF10996.8 AAG07002.1 - 8.7e-27 93.6 0.0 1.9e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 AAG07002.1 - 2.3e-17 62.7 0.1 5.5e-17 61.5 0.1 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 AAG07002.1 - 7.5e-11 42.4 0.0 2.4e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 AAG07002.1 - 8.7e-10 38.3 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AAG07002.1 - 3.8e-09 36.3 0.0 5.5e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAG07002.1 - 0.0003 20.7 0.0 0.0021 18.0 0.0 2.3 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lysine_decarbox PF03641.14 AAG07003.1 - 2.2e-29 102.2 0.0 3.7e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AAG07003.1 - 1.8e-13 50.3 0.0 3.4e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 AAG07003.1 - 0.0083 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A STALD PF18185.1 AAG07003.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family Methyltrn_RNA_4 PF09936.9 AAG07003.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Cas3_C PF18395.1 AAG07003.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Cas3 C-terminal domain RecX PF02631.16 AAG07004.1 - 5.3e-34 117.3 2.2 3.3e-32 111.5 0.5 1.7 1 1 1 2 2 2 2 RecX family DUF494 PF04361.13 AAG07004.1 - 0.028 14.3 0.0 3.6 7.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF494) SelB-wing_2 PF09106.11 AAG07004.1 - 0.073 13.3 2.9 0.21 11.8 0.3 2.4 2 1 0 2 2 2 0 Elongation factor SelB, winged helix DUF3427 PF11907.8 AAG07004.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) RecA PF00154.21 AAG07005.1 - 6.6e-144 478.1 1.9 8e-144 477.9 1.9 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AAG07005.1 - 2.3e-12 46.7 0.5 1.1e-11 44.5 0.5 1.8 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AAG07005.1 - 5.2e-08 32.5 2.0 4.6e-06 26.1 1.6 3.1 2 1 0 2 2 2 1 KaiC ATPase_2 PF01637.18 AAG07005.1 - 8.8e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 AAG07005.1 - 0.00065 20.1 0.1 0.0013 19.1 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 AAG07005.1 - 0.00078 19.4 0.0 0.0062 16.4 0.0 2.1 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.16 AAG07005.1 - 0.0046 16.6 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_25 PF13481.6 AAG07005.1 - 0.0049 16.5 1.4 0.15 11.7 1.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AAG07005.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 AAG07005.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 AAG07005.1 - 0.02 15.3 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AAG07005.1 - 0.071 13.6 0.1 0.13 12.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 AAG07005.1 - 0.096 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAG07005.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAG07005.1 - 0.18 12.2 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase CinA PF02464.17 AAG07006.1 - 4.3e-55 185.5 0.3 4.8e-55 185.4 0.3 1.0 1 0 0 1 1 1 1 Competence-damaged protein PD40 PF07676.12 AAG07007.1 - 7e-06 25.8 5.3 0.015 15.2 0.1 4.8 5 1 0 5 5 5 2 WD40-like Beta Propeller Repeat MutS_V PF00488.21 AAG07008.1 - 4.7e-86 287.6 0.0 7.9e-86 286.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 AAG07008.1 - 6.1e-43 145.7 0.0 1e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 AAG07008.1 - 2.2e-38 132.4 2.8 3.7e-38 131.7 2.8 1.4 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 AAG07008.1 - 2.2e-31 108.9 0.0 4.6e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 AAG07008.1 - 8.3e-30 103.0 0.0 2.4e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV DUF3470 PF11953.8 AAG07009.1 - 7.5e-24 83.4 0.5 9.6e-24 83.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3470) Fer4 PF00037.27 AAG07009.1 - 1.4e-08 34.2 19.0 5e-06 26.1 3.9 3.1 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_10 PF13237.6 AAG07009.1 - 3.4e-07 30.3 8.4 0.00036 20.6 0.2 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG07009.1 - 2.3e-06 27.4 18.4 0.00026 20.9 4.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAG07009.1 - 2.9e-06 28.1 9.0 0.00073 20.4 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAG07009.1 - 3.1e-06 27.2 12.3 0.0013 18.8 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAG07009.1 - 1.3e-05 25.7 15.9 7.6e-05 23.2 16.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG07009.1 - 2.1e-05 24.6 25.3 0.00053 20.1 14.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG07009.1 - 7e-05 23.3 7.8 0.0033 17.9 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAG07009.1 - 0.00015 21.7 13.5 0.013 15.6 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAG07009.1 - 0.00074 19.9 8.9 0.0093 16.4 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG07009.1 - 0.0063 16.9 16.0 0.035 14.6 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAG07009.1 - 1.3 10.2 20.0 0.96 10.5 7.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.6 AAG07009.1 - 1.5 9.0 10.1 2.9 8.1 10.2 1.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAG07009.1 - 4.4 7.1 14.6 0.37 10.6 4.0 2.2 1 1 1 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Sigma70_r3 PF04539.16 AAG07010.1 - 3.7e-23 81.4 1.0 2.9e-20 72.1 0.3 2.6 2 0 0 2 2 2 2 Sigma-70 region 3 Sigma70_r2 PF04542.14 AAG07010.1 - 4.5e-22 77.6 0.1 8.1e-22 76.8 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG07010.1 - 2.3e-16 59.0 4.4 1.3e-15 56.6 3.9 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AAG07010.1 - 1.5e-13 50.5 0.0 3.4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Sigma70_r4_2 PF08281.12 AAG07010.1 - 0.045 13.4 0.1 6.5 6.5 0.2 3.0 2 1 0 2 2 2 0 Sigma-70, region 4 KinB_sensor PF16767.5 AAG07010.1 - 0.048 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Peptidase_M23 PF01551.22 AAG07011.1 - 3.5e-30 104.1 0.5 3.5e-30 104.1 0.5 1.9 2 0 0 2 2 2 1 Peptidase family M23 LysM PF01476.20 AAG07011.1 - 1.2e-13 50.9 0.0 2.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 LysM domain Biotin_lipoyl_2 PF13533.6 AAG07011.1 - 0.00021 21.0 0.0 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 AAG07011.1 - 0.033 14.1 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PCMT PF01135.19 AAG07012.1 - 2.2e-65 220.3 0.0 2.6e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AAG07012.1 - 2.8e-05 23.9 0.0 5.5e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG07012.1 - 0.0015 19.2 0.0 0.0026 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AAG07012.1 - 0.0016 17.5 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 AAG07012.1 - 0.0036 17.0 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 AAG07012.1 - 0.011 16.3 0.0 0.033 14.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain POTRA PF07244.15 AAG07012.1 - 0.068 13.7 0.0 9.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Surface antigen variable number repeat Methyltransf_23 PF13489.6 AAG07012.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 AAG07012.1 - 0.11 13.6 0.2 0.61 11.1 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 AAG07012.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SurE PF01975.17 AAG07013.1 - 5e-55 186.3 0.0 6.1e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE TruD PF01142.18 AAG07014.1 - 4.2e-58 197.1 0.0 2.8e-38 131.8 0.0 2.1 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) YgbB PF02542.16 AAG07015.1 - 7.9e-68 227.6 0.4 8.8e-68 227.5 0.4 1.0 1 0 0 1 1 1 1 YgbB family Esterase PF00756.20 AAG07016.1 - 4.4e-63 213.3 0.0 5.1e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 AAG07016.1 - 1e-05 25.1 0.0 6.5e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 AAG07016.1 - 8.7e-05 22.1 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAG07016.1 - 0.00068 19.0 0.1 0.014 14.7 0.0 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 AAG07016.1 - 0.14 11.7 0.0 1.3 8.6 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family ADH_N PF08240.12 AAG07017.1 - 1.8e-26 92.2 1.9 3.1e-26 91.4 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAG07017.1 - 1.1e-25 90.1 0.1 1.9e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAG07017.1 - 1.2e-07 32.9 0.0 2.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AAG07017.1 - 8.6e-05 22.1 0.0 0.00024 20.7 0.0 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Met_10 PF02475.16 AAG07017.1 - 0.0071 16.1 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MinC_C PF03775.16 AAG07017.1 - 0.063 13.3 1.8 1.1 9.3 0.9 2.2 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain ADH_N_2 PF16884.5 AAG07017.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 AAG07017.1 - 0.15 11.4 0.2 0.26 10.6 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CLLAC PF15675.5 AAG07017.1 - 0.41 10.2 2.5 0.85 9.2 2.5 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain LysR_substrate PF03466.20 AAG07018.1 - 1.2e-48 165.3 4.8 1.3e-48 165.2 1.6 1.9 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07018.1 - 1.3e-19 69.9 1.6 1.3e-19 69.9 1.6 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG07018.1 - 0.037 13.9 0.7 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 MarR family MarR PF01047.22 AAG07018.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 MarR family Sulf_transp PF04143.14 AAG07019.1 - 4.9e-45 154.4 35.6 8.9e-26 91.2 17.2 2.6 3 0 0 3 3 3 2 Sulphur transport TusA PF01206.17 AAG07020.1 - 2.7e-18 65.5 0.0 3e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AAG07020.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) IspD PF01128.19 AAG07021.1 - 2.2e-64 217.3 0.0 2.6e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 AAG07021.1 - 3.5e-10 40.5 4.5 4.5e-10 40.1 4.3 1.2 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF2145 PF09916.9 AAG07021.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) DivIC PF04977.15 AAG07022.1 - 2.5e-23 81.6 0.7 2.9e-23 81.4 0.7 1.1 1 0 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 AAG07022.1 - 0.0081 16.6 3.0 0.011 16.1 3.0 1.1 1 0 0 1 1 1 1 Cell division protein ZapB NRBF2 PF08961.10 AAG07022.1 - 0.013 15.1 0.8 0.015 14.9 0.8 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator LysM PF01476.20 AAG07022.1 - 0.022 14.8 0.0 3.5 7.8 0.0 3.0 3 0 0 3 3 3 0 LysM domain CENP-H PF05837.12 AAG07022.1 - 0.038 14.4 1.2 0.046 14.1 1.2 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) YabA PF06156.13 AAG07022.1 - 0.1 13.2 1.1 0.12 13.0 1.1 1.1 1 0 0 1 1 1 0 Initiation control protein YabA PKcGMP_CC PF16808.5 AAG07022.1 - 0.15 11.9 1.8 2.2 8.2 0.2 2.4 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 AAG07022.1 - 0.3 11.7 2.5 0.41 11.3 2.5 1.2 1 0 0 1 1 1 0 SlyX Enolase_C PF00113.22 AAG07023.1 - 1.6e-137 457.6 0.5 2e-137 457.3 0.5 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AAG07023.1 - 2.3e-58 196.0 0.3 4e-58 195.3 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AAG07023.1 - 1.1e-06 28.3 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 AAG07023.1 - 5.9e-06 25.6 0.8 1.2e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus DAHP_synth_1 PF00793.20 AAG07024.1 - 2.1e-80 269.5 0.0 2.4e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CTP_synth_N PF06418.14 AAG07025.1 - 1.2e-124 414.9 0.1 2.5e-124 413.8 0.1 1.5 2 0 0 2 2 2 1 CTP synthase N-terminus GATase PF00117.28 AAG07025.1 - 4.7e-59 199.4 0.0 1e-58 198.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAG07025.1 - 4e-08 33.3 0.6 6.6e-07 29.3 0.2 2.6 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 AAG07025.1 - 0.0026 17.8 0.0 0.0038 17.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_3 PF01171.20 AAG07026.1 - 6.7e-59 198.7 0.0 8.7e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 AAG07026.1 - 2.4e-17 62.1 1.9 1.4e-16 59.7 0.2 2.4 2 0 0 2 2 2 1 TilS substrate C-terminal domain TilS PF09179.11 AAG07026.1 - 2.8e-13 50.2 6.1 2.8e-13 50.2 6.1 3.9 4 0 0 4 4 4 1 TilS substrate binding domain PAPS_reduct PF01507.19 AAG07026.1 - 0.06 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 AAG07026.1 - 0.17 10.7 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase ACCA PF03255.14 AAG07027.1 - 3.9e-64 214.9 0.0 5.4e-64 214.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 AAG07027.1 - 4.4e-17 61.9 0.0 4.7e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAG07027.1 - 0.00058 19.4 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) DNA_pol3_alpha PF07733.12 AAG07028.1 - 9.4e-103 343.3 0.0 1.5e-102 342.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AAG07028.1 - 2.6e-68 228.6 0.0 5.9e-67 224.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 AAG07028.1 - 1.4e-41 142.6 0.0 3.1e-41 141.4 0.0 1.7 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 AAG07028.1 - 2.4e-26 91.8 0.0 9.2e-26 89.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 AAG07028.1 - 1.8e-10 40.6 0.0 6.8e-10 38.8 0.1 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 AAG07028.1 - 0.0041 17.3 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 AAG07028.1 - 0.03 14.4 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) HPD PF05044.12 AAG07028.1 - 0.22 11.4 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Homeo-prospero domain Na_Ala_symp PF01235.17 AAG07029.1 - 1.8e-160 534.6 27.5 2.2e-160 534.3 27.5 1.0 1 0 0 1 1 1 1 Sodium:alanine symporter family DUF5373 PF17343.2 AAG07029.1 - 1.8 8.3 9.2 1 9.2 3.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5373) RNase_HII PF01351.18 AAG07030.1 - 2.5e-42 145.0 0.0 2.9e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII LpxB PF02684.15 AAG07031.1 - 2.8e-121 404.9 0.0 3.3e-121 404.7 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Acetyltransf_11 PF13720.6 AAG07032.1 - 4.6e-27 94.3 0.0 6.7e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 AAG07032.1 - 1.9e-23 81.2 15.8 1.6e-08 33.9 1.5 5.6 3 2 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 AAG07032.1 - 0.026 13.5 0.0 0.32 9.9 0.0 2.0 1 1 1 2 2 2 0 L-fucokinase DUF2407_C PF13373.6 AAG07032.1 - 0.037 14.2 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain FabA PF07977.13 AAG07033.1 - 1.1e-38 132.0 0.0 1.2e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain 4HBT PF03061.22 AAG07033.1 - 0.00024 21.4 0.0 0.00033 21.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AAG07033.1 - 0.0023 17.5 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain 4HBT_2 PF13279.6 AAG07033.1 - 0.034 14.6 0.0 0.037 14.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Hexapep PF00132.24 AAG07034.1 - 3.8e-28 96.1 30.2 1.5e-06 27.7 0.4 6.0 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) LpxD PF04613.14 AAG07034.1 - 1.9e-22 78.8 0.2 3.3e-22 78.0 0.2 1.4 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep_2 PF14602.6 AAG07034.1 - 3.8e-06 26.5 29.7 0.014 15.2 6.8 5.5 4 2 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase HSBP1 PF06825.12 AAG07034.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 AAG07034.1 - 0.11 12.4 0.4 0.18 11.7 0.4 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin OmpH PF03938.14 AAG07035.1 - 3.8e-20 72.6 12.6 4.4e-20 72.4 12.6 1.0 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF2278 PF10042.9 AAG07035.1 - 0.008 16.2 0.4 0.0099 15.9 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) PhaP_Bmeg PF09602.10 AAG07035.1 - 0.037 13.9 2.7 0.056 13.4 2.7 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) UPF0242 PF06785.11 AAG07035.1 - 0.048 13.8 3.3 0.061 13.4 3.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus cwf18 PF08315.12 AAG07035.1 - 0.12 13.1 7.3 0.15 12.7 7.3 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Bac_surface_Ag PF01103.23 AAG07036.1 - 2.8e-96 322.8 11.3 4.3e-96 322.2 11.3 1.3 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 AAG07036.1 - 3.2e-71 235.9 13.8 2.5e-17 63.2 0.2 5.4 5 0 0 5 5 5 5 Surface antigen variable number repeat POTRA_1 PF08478.10 AAG07036.1 - 4.8e-13 49.2 0.6 0.012 15.9 0.0 5.5 5 1 0 5 5 5 3 POTRA domain, FtsQ-type POTRA_2 PF08479.11 AAG07036.1 - 4.5e-08 32.8 5.0 0.27 11.1 0.1 5.5 6 0 0 6 6 6 3 POTRA domain, ShlB-type YqfD PF06898.11 AAG07036.1 - 0.0017 17.2 0.1 0.0047 15.8 0.1 1.7 1 0 0 1 1 1 1 Putative stage IV sporulation protein YqfD Peptidase_M50 PF02163.22 AAG07037.1 - 1.2e-83 280.2 0.0 1.5e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 AAG07037.1 - 4.8e-19 68.0 7.0 2.6e-09 36.8 0.5 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 AAG07037.1 - 3.1e-15 56.3 0.0 1.1e-09 38.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AAG07037.1 - 6.2e-12 45.7 0.0 0.00019 21.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 AAG07037.1 - 5.4e-06 26.3 2.3 0.053 13.5 0.1 3.1 4 0 0 4 4 4 2 Tricorn protease PDZ domain Peptidase_M50B PF13398.6 AAG07037.1 - 6 6.5 9.7 1.1 8.8 0.5 2.9 3 0 0 3 3 3 0 Peptidase M50B-like DXPR_C PF13288.6 AAG07038.1 - 1.4e-43 147.8 0.0 2.1e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 AAG07038.1 - 4.8e-43 146.9 0.4 9.5e-43 146.0 0.4 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 AAG07038.1 - 1.9e-38 130.5 0.0 3.9e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Semialdhyde_dh PF01118.24 AAG07038.1 - 0.081 13.4 0.4 0.6 10.6 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain CTP_transf_1 PF01148.20 AAG07039.1 - 2.5e-66 224.2 14.5 2.8e-66 224.0 14.5 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Prenyltransf PF01255.19 AAG07040.1 - 1.9e-77 259.8 0.0 2.1e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.24 AAG07040.1 - 0.0098 15.3 0.4 0.018 14.5 0.4 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel RRF PF01765.19 AAG07041.1 - 1.5e-61 207.1 0.7 1.9e-61 206.7 0.7 1.1 1 0 0 1 1 1 1 Ribosome recycling factor SpoIIIAH PF12685.7 AAG07041.1 - 1.3 8.8 7.3 1.5 8.6 7.3 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein AA_kinase PF00696.28 AAG07042.1 - 9.3e-27 94.2 0.2 1.1e-26 93.9 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family EF_TS PF00889.19 AAG07043.1 - 7.6e-59 198.8 1.6 7.6e-59 198.8 1.6 2.0 3 0 0 3 3 3 1 Elongation factor TS Ribosomal_L12 PF00542.19 AAG07043.1 - 0.0018 18.6 1.5 0.0018 18.6 1.5 3.2 4 0 0 4 4 4 1 Ribosomal protein L7/L12 C-terminal domain UBA PF00627.31 AAG07043.1 - 0.0041 17.0 0.3 0.84 9.6 0.0 3.2 3 0 0 3 3 3 1 UBA/TS-N domain HOIP-UBA PF16678.5 AAG07043.1 - 0.014 15.4 2.7 0.45 10.5 0.1 3.1 2 1 1 3 3 3 0 HOIP UBA domain pair TAP_C PF03943.13 AAG07043.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain Ribosomal_S2 PF00318.20 AAG07044.1 - 7.8e-95 316.2 0.0 8.9e-95 316.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Peptidase_M24 PF00557.24 AAG07045.1 - 9.4e-60 201.9 0.2 1.1e-59 201.7 0.2 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 RsmF_methylt_CI PF17126.5 AAG07045.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 RsmF rRNA methyltransferase first C-terminal domain NTS PF15447.6 AAG07045.1 - 0.15 12.6 0.2 7.3 7.2 0.0 2.4 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 GlnD_UR_UTase PF08335.11 AAG07046.1 - 7.4e-37 126.7 0.6 2.2e-36 125.2 0.6 1.9 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase HD PF01966.22 AAG07046.1 - 1.1e-10 41.7 0.0 2.8e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 HD domain ACT PF01842.25 AAG07046.1 - 1.6e-08 34.2 0.3 1.7e-07 30.9 0.0 2.7 2 0 0 2 2 2 1 ACT domain NTP_transf_2 PF01909.23 AAG07046.1 - 4.6e-08 33.2 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF294 PF03445.13 AAG07046.1 - 5.6e-05 23.0 0.0 0.00037 20.3 0.0 2.3 2 0 0 2 2 2 1 Putative nucleotidyltransferase DUF294 GlnE PF03710.15 AAG07046.1 - 0.0088 15.5 0.3 0.041 13.3 0.0 2.2 2 0 0 2 2 2 1 Glutamate-ammonia ligase adenylyltransferase ACT_6 PF13740.6 AAG07046.1 - 0.079 12.9 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 ACT domain Polbeta PF18765.1 AAG07046.1 - 0.081 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PPC PF04151.15 AAG07046.1 - 0.12 13.5 0.4 0.87 10.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Aminotran_1_2 PF00155.21 AAG07047.1 - 5.1e-44 150.9 0.0 6.1e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AAG07047.1 - 3.3e-06 26.1 0.0 4.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Prenyltrans PF00432.21 AAG07047.1 - 0.14 11.9 0.0 0.58 9.9 0.0 2.1 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Na_H_Exchanger PF00999.21 AAG07048.1 - 1e-84 284.6 38.3 1.3e-84 284.3 38.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AlkA_N PF06029.11 AAG07050.1 - 0.043 14.1 0.2 0.054 13.8 0.2 1.1 1 0 0 1 1 1 0 AlkA N-terminal domain CxxCxxCC PF03692.15 AAG07051.1 - 4e-10 40.2 2.0 4.6e-10 40.1 2.0 1.1 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain ArsC PF03960.15 AAG07052.1 - 3.1e-19 68.8 0.0 3.3e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AAG07052.1 - 0.0031 17.7 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Ish1 PF10281.9 AAG07052.1 - 0.0053 17.0 0.1 2.7 8.4 0.1 2.4 1 1 1 2 2 2 2 Putative stress-responsive nuclear envelope protein GST_N_3 PF13417.6 AAG07052.1 - 0.12 12.8 0.0 1.1 9.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain LysE PF01810.18 AAG07053.1 - 1.6e-26 93.0 10.1 1.9e-26 92.8 10.1 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAG07053.1 - 0.14 11.9 3.3 0.091 12.4 1.5 1.6 1 1 0 1 1 1 0 Integral membrane protein TerC family THDPS_M PF14789.6 AAG07054.1 - 5.6e-16 58.3 0.0 1.2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase middle Hexapep_2 PF14602.6 AAG07054.1 - 6e-12 45.1 5.0 6e-12 45.1 5.0 2.7 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase THDPS_N PF14790.6 AAG07054.1 - 6.7e-06 26.0 0.0 9.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep PF00132.24 AAG07054.1 - 0.023 14.4 7.8 0.19 11.5 1.3 3.8 3 1 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) Aminotran_5 PF00266.19 AAG07055.1 - 5.8e-137 456.6 0.0 6.6e-137 456.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAG07055.1 - 1.6e-06 27.5 0.0 4.9e-05 22.7 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II SufE PF02657.15 AAG07056.1 - 1.1e-38 131.8 0.0 1.3e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain DUF4340 PF14238.6 AAG07057.1 - 5.6e-19 68.9 0.0 8.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4340) DUF2749 PF10907.8 AAG07057.1 - 0.031 14.4 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) ABC_transp_aux PF09822.9 AAG07058.1 - 4.5e-69 232.9 0.0 1e-68 231.7 0.0 1.6 2 0 0 2 2 2 1 ABC-type uncharacterized transport system Mobilization_B PF17511.2 AAG07058.1 - 0.063 13.6 1.0 0.13 12.7 1.0 1.4 1 0 0 1 1 1 0 Mobilization protein B DUF3545 PF12065.8 AAG07058.1 - 0.13 12.3 0.3 0.3 11.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) FapA PF03961.13 AAG07058.1 - 0.47 9.0 2.2 0.67 8.5 2.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A 5_nucleotid PF05761.14 AAG07058.1 - 0.6 9.0 1.6 0.82 8.5 1.6 1.1 1 0 0 1 1 1 0 5' nucleotidase family ABC2_membrane_2 PF12679.7 AAG07059.1 - 3e-09 36.6 17.3 1.2e-08 34.7 17.3 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AAG07059.1 - 1.5e-07 31.2 10.7 6.9e-07 29.0 10.4 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAG07059.1 - 1.4e-06 28.4 6.9 1.4e-06 28.4 6.9 1.6 2 1 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AAG07059.1 - 1.8e-06 27.3 23.6 1.3e-05 24.5 23.7 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAG07059.1 - 4.9e-06 26.1 17.0 4.9e-06 26.1 17.0 1.3 1 1 0 1 1 1 1 ABC-2 type transporter CcmB PF03379.13 AAG07059.1 - 9.1e-06 25.3 5.8 9.1e-06 25.3 5.8 2.4 1 1 1 2 2 2 1 CcmB protein YrhC PF14143.6 AAG07059.1 - 4.3 7.5 8.5 2.3 8.4 1.2 2.9 3 0 0 3 3 3 0 YrhC-like protein ABC_tran PF00005.27 AAG07060.1 - 1.1e-25 90.7 0.0 1.8e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07060.1 - 4.5e-09 36.5 1.1 2.3e-05 24.4 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAG07060.1 - 0.00069 19.4 0.0 0.69 9.6 0.0 2.1 1 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AAG07060.1 - 0.048 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG07060.1 - 0.06 13.8 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG07060.1 - 0.063 13.6 0.3 0.22 11.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAG07060.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAG07060.1 - 0.068 13.3 0.5 0.82 9.8 0.5 2.5 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAG07060.1 - 0.14 11.6 0.0 13 5.1 0.0 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAG07060.1 - 0.16 11.7 0.3 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Acyltransferase PF01553.21 AAG07061.1 - 3.8e-20 71.9 0.0 7.4e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase YscW PF09619.10 AAG07062.1 - 2.4e-33 114.7 0.0 2.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) DUF4197 PF13852.6 AAG07063.1 - 7.7e-76 254.3 4.1 8.7e-76 254.1 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4197) ACR_tran PF00873.19 AAG07064.1 - 3.3e-172 574.6 0.0 4.1e-172 574.3 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG07064.1 - 1.8e-07 30.4 13.3 1.8e-07 30.4 13.3 2.5 2 0 0 2 2 2 1 MMPL family Patched PF02460.18 AAG07064.1 - 9.8 4.1 10.4 15 3.5 10.4 1.2 1 0 0 1 1 1 0 Patched family HlyD_D23 PF16576.5 AAG07065.1 - 1.7e-20 73.2 1.0 4.1e-20 71.9 1.0 1.6 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG07065.1 - 1.9e-19 70.3 1.6 7.8e-16 58.7 0.0 2.7 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG07065.1 - 8.1e-12 44.8 5.4 2.9e-07 30.2 0.7 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG07065.1 - 3.1e-06 26.9 0.0 0.061 13.2 0.0 2.7 3 0 0 3 3 3 2 Biotin-requiring enzyme HlyD PF00529.20 AAG07065.1 - 0.04 13.8 0.4 0.29 11.0 0.4 2.3 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS PTS_EIIA_1 PF00358.20 AAG07065.1 - 0.041 13.6 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 FliJ PF02050.16 AAG07065.1 - 0.045 14.0 5.7 0.072 13.3 5.7 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein FPP PF05911.11 AAG07065.1 - 0.054 11.7 0.0 0.07 11.3 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TetR_C_7 PF14246.6 AAG07066.1 - 4.8e-31 107.3 0.7 1.5e-30 105.6 1.0 1.7 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AAG07066.1 - 4.9e-17 61.4 0.1 1.5e-16 59.9 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AAG07066.1 - 7.2e-08 32.7 0.2 1.1e-07 32.1 0.2 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAG07066.1 - 0.0097 16.1 0.3 0.015 15.5 0.3 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal HTH_40 PF14493.6 AAG07066.1 - 0.037 14.5 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain LacI PF00356.21 AAG07066.1 - 0.059 13.2 0.4 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family TetR_C_31 PF17940.1 AAG07066.1 - 0.065 13.4 2.2 0.063 13.5 0.9 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 AAG07066.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase GerE PF00196.19 AAG07066.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family p450 PF00067.22 AAG07067.1 - 1.3e-44 152.8 0.0 3.2e-40 138.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 SAM_MT PF04445.13 AAG07068.1 - 4.1e-94 314.3 0.0 4.8e-94 314.1 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Extensin-like_C PF06904.12 AAG07069.1 - 4.9e-61 205.8 0.0 5.7e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Extensin-like protein C-terminus PEP_mutase PF13714.6 AAG07070.1 - 2.1e-71 240.2 1.8 2.4e-71 240.0 1.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Acyl-CoA_dh_N PF02771.16 AAG07070.1 - 0.11 13.2 0.1 0.25 12.0 0.1 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain DUF72 PF01904.18 AAG07071.1 - 4e-52 177.5 0.0 4.6e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 Peptidase_M22 PF00814.25 AAG07073.1 - 1.1e-28 100.8 0.1 2.3e-28 99.7 0.1 1.6 1 1 0 1 1 1 1 Glycoprotease family ADK PF00406.22 AAG07074.1 - 1.1e-56 191.1 0.0 1.4e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AAG07074.1 - 2.6e-25 89.4 0.3 4.8e-25 88.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 AAG07074.1 - 2.6e-17 62.5 0.1 5.7e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 AAG07074.1 - 2.1e-05 24.9 1.7 0.018 15.3 0.0 3.2 2 2 1 3 3 3 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 AAG07074.1 - 7.2e-05 23.3 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAG07074.1 - 0.0026 17.9 0.1 0.045 13.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AAG07074.1 - 0.03 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase PEPcase PF00311.17 AAG07075.1 - 1.3e-274 913.2 0.0 1.6e-274 912.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 AAG07075.1 - 0.0016 17.0 0.0 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase HAMP PF00672.25 AAG07075.1 - 0.052 13.9 1.5 0.14 12.5 0.2 2.4 2 0 0 2 2 2 0 HAMP domain GHMP_kinases_C PF08544.13 AAG07075.1 - 0.51 10.7 2.9 13 6.2 0.2 3.6 3 0 0 3 3 3 0 GHMP kinases C terminal MerR_1 PF13411.6 AAG07077.1 - 3.3e-22 78.4 0.1 6.1e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AAG07077.1 - 4.5e-21 75.1 4.2 3.3e-20 72.4 5.7 1.6 2 0 0 2 2 2 1 MerR, DNA binding MerR PF00376.23 AAG07077.1 - 2.5e-18 65.5 0.7 4.9e-18 64.6 0.7 1.5 1 0 0 1 1 1 1 MerR family regulatory protein DUF4315 PF14193.6 AAG07077.1 - 0.0066 16.4 0.0 3.1 7.9 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4315) HTH_20 PF12840.7 AAG07077.1 - 0.015 15.3 2.1 0.46 10.6 0.0 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain Pkip-1 PF06878.11 AAG07077.1 - 0.072 13.2 0.1 0.22 11.6 0.0 1.7 1 1 1 2 2 2 0 Pkip-1 protein GnsAB_toxin PF08178.11 AAG07077.1 - 0.094 12.7 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system HTH_3 PF01381.22 AAG07077.1 - 0.15 12.1 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix E1-E2_ATPase PF00122.20 AAG07078.1 - 8.2e-55 185.1 0.1 2e-54 183.9 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAG07078.1 - 1.2e-41 143.3 2.0 1.8e-41 142.8 2.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAG07078.1 - 0.00012 22.4 0.0 0.00029 21.2 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AAG07078.1 - 0.00064 19.5 0.3 0.046 13.5 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5548 PF17702.1 AAG07078.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5548) DUF4398 PF14346.6 AAG07079.1 - 3.7e-18 65.9 14.6 5.5e-18 65.4 14.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) Spc7 PF08317.11 AAG07079.1 - 0.01 14.7 3.5 0.012 14.5 3.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AP-5_subunit_s1 PF15001.6 AAG07079.1 - 0.12 12.4 2.0 0.14 12.2 2.0 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 HemY_N PF07219.13 AAG07079.1 - 1 9.6 7.4 2.1 8.6 5.7 2.1 1 1 1 2 2 2 0 HemY protein N-terminus OmpA PF00691.20 AAG07080.1 - 5.4e-25 87.6 0.7 1.4e-24 86.3 0.0 2.0 2 0 0 2 2 2 1 OmpA family DUF4398 PF14346.6 AAG07080.1 - 5.6e-12 46.1 9.6 5.6e-12 46.1 9.6 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4398) Pilus_CpaD PF09476.10 AAG07080.1 - 0.0013 18.5 8.2 0.039 13.7 0.1 2.2 1 1 1 2 2 2 2 Pilus biogenesis CpaD protein (pilus_cpaD) SEFIR PF08357.11 AAG07080.1 - 0.0073 16.6 0.1 0.59 10.4 0.0 2.2 1 1 1 2 2 2 1 SEFIR domain DUF382 PF04037.13 AAG07080.1 - 0.061 13.5 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF382) Biotin_lipoyl_2 PF13533.6 AAG07080.1 - 0.85 9.5 5.4 0.91 9.4 0.0 3.2 3 1 1 4 4 4 0 Biotin-lipoyl like Macro PF01661.21 AAG07081.1 - 1.9e-43 147.3 0.2 2.5e-43 146.9 0.2 1.1 1 0 0 1 1 1 1 Macro domain Apc13p PF05839.11 AAG07082.1 - 0.055 13.7 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Apc13p protein Pox_A21 PF05323.12 AAG07082.1 - 0.2 12.3 0.0 0.27 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A21 Protein Hydrolase_4 PF12146.8 AAG07083.1 - 8.4e-19 67.8 0.3 2.2e-15 56.6 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG07083.1 - 1.4e-12 47.8 0.2 1.7e-11 44.2 0.2 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG07083.1 - 1.9e-09 38.5 7.9 3.2e-09 37.7 7.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AAG07083.1 - 2.2e-07 30.8 0.5 0.0011 18.6 0.2 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 AAG07083.1 - 0.00039 20.1 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AAG07083.1 - 0.00056 19.5 0.0 0.0017 17.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 AAG07083.1 - 0.00076 18.2 0.0 0.35 9.5 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 AAG07083.1 - 0.0024 17.5 0.0 0.026 14.2 0.0 2.4 2 2 1 3 3 3 1 Serine hydrolase (FSH1) DUF3530 PF12048.8 AAG07083.1 - 0.0037 16.7 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3530) Abhydrolase_3 PF07859.13 AAG07083.1 - 0.035 13.9 0.1 0.061 13.2 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 AAG07083.1 - 0.037 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein BAAT_C PF08840.11 AAG07083.1 - 0.054 13.4 0.0 0.51 10.2 0.0 2.1 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 AAG07083.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family AIM24 PF01987.17 AAG07084.1 - 4.7e-64 215.9 0.7 5.6e-64 215.6 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4082 PF13313.6 AAG07084.1 - 0.13 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) DUF1704 PF08014.11 AAG07085.1 - 2.6e-133 444.6 0.0 3.1e-133 444.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) PAH PF02671.21 AAG07085.1 - 0.022 14.9 0.0 0.07 13.3 0.0 1.9 1 0 0 1 1 1 0 Paired amphipathic helix repeat TetR_N PF00440.23 AAG07087.1 - 6.6e-08 32.2 0.1 2.2e-07 30.6 0.1 2.0 1 1 1 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AAG07087.1 - 1.8e-07 31.3 3.8 1.8e-07 31.3 3.8 2.8 2 2 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAG07087.1 - 0.011 15.9 2.4 0.011 15.9 2.4 3.0 2 2 1 3 3 3 0 BetI-type transcriptional repressor, C-terminal Peptidase_M35 PF02102.15 AAG07087.1 - 0.035 13.0 0.4 0.045 12.6 0.4 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Glyoxalase_6 PF18029.1 AAG07087.1 - 1.3 9.8 4.0 0.59 10.9 0.5 2.0 2 0 0 2 2 2 0 Glyoxalase-like domain tRNA-synt_2 PF00152.20 AAG07088.1 - 1.4e-83 280.6 0.6 1.8e-83 280.3 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AAG07088.1 - 8.5e-08 32.1 0.0 3.1e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AAG07088.1 - 3e-07 30.2 1.0 0.0014 18.1 0.2 3.1 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) GGDEF PF00990.21 AAG07089.1 - 6.8e-50 169.0 0.0 1.1e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAG07089.1 - 1.8e-19 69.9 0.1 3.8e-19 68.9 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain GGDEF_2 PF17853.1 AAG07089.1 - 0.021 15.1 2.1 0.084 13.1 0.1 2.5 3 0 0 3 3 3 0 GGDEF-like domain CheB_methylest PF01339.17 AAG07090.1 - 1.2e-57 194.3 0.1 2.6e-57 193.2 0.0 1.6 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AAG07090.1 - 9.6e-17 61.2 0.2 3.3e-16 59.4 0.2 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Peptidase_S9 PF00326.21 AAG07090.1 - 0.0052 16.3 0.1 0.024 14.1 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Response_reg PF00072.24 AAG07091.1 - 8.4e-24 83.9 0.1 1.6e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain CheW PF01584.19 AAG07091.1 - 6.9e-19 67.9 1.1 1.5e-18 66.8 0.4 1.9 2 0 0 2 2 2 1 CheW-like domain Hpt PF01627.23 AAG07091.1 - 1.4e-14 54.1 6.7 1.4e-14 54.1 6.7 3.5 3 1 1 4 4 4 1 Hpt domain HATPase_c PF02518.26 AAG07091.1 - 1.2e-13 51.5 0.0 2.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAG07091.1 - 0.11 12.9 2.8 0.35 11.3 2.8 2.0 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain HATPase_c_5 PF14501.6 AAG07091.1 - 0.18 11.7 0.0 0.65 9.9 0.0 1.9 1 1 0 1 1 1 0 GHKL domain Serine_rich PF08824.10 AAG07091.1 - 0.21 11.6 1.3 0.48 10.4 0.7 1.6 1 1 1 2 2 2 0 Serine rich protein interaction domain CheW PF01584.19 AAG07092.1 - 1.2e-21 76.7 0.2 1.9e-21 76.1 0.1 1.4 2 0 0 2 2 2 1 CheW-like domain CheR PF01739.18 AAG07093.1 - 8.2e-37 126.6 0.0 1.1e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 AAG07093.1 - 8.2e-06 26.4 0.0 0.00011 22.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain TPR_17 PF13431.6 AAG07093.1 - 2.5e-05 24.3 2.6 0.00099 19.3 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_11 PF08241.12 AAG07093.1 - 0.0003 21.4 0.0 0.0013 19.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG07093.1 - 0.00048 20.8 0.0 0.0017 19.0 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG07093.1 - 0.00081 19.3 0.0 0.0021 17.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TPR_2 PF07719.17 AAG07093.1 - 0.00082 19.3 13.7 0.0027 17.7 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAG07093.1 - 0.0028 17.4 4.5 0.014 15.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 AAG07093.1 - 0.0031 17.6 2.7 0.015 15.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 AAG07093.1 - 0.0047 16.9 0.8 0.0047 16.9 0.8 2.0 1 1 1 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_19 PF14559.6 AAG07093.1 - 0.019 15.5 10.9 0.061 13.8 6.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAG07093.1 - 0.088 13.7 15.3 1.3 10.1 1.1 4.3 2 1 2 4 4 3 0 Tetratricopeptide repeat CheR_N PF03705.15 AAG07093.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 1 0 CheR methyltransferase, all-alpha domain TPR_16 PF13432.6 AAG07093.1 - 0.2 12.3 25.4 0.72 10.5 12.8 3.0 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAG07093.1 - 0.27 11.6 14.2 0.096 13.0 7.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAG07093.1 - 0.48 10.4 15.8 0.049 13.5 4.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAG07093.1 - 1.9 9.4 22.8 1.3 9.8 10.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CheW PF01584.19 AAG07094.1 - 8.4e-25 87.0 0.0 9.6e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 CheW-like domain MCPsignal PF00015.21 AAG07095.1 - 1.6e-35 122.4 35.7 5.7e-34 117.4 17.5 2.8 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAG07095.1 - 2.4e-20 72.8 0.6 2.4e-20 72.8 0.6 3.6 4 0 0 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAG07095.1 - 1.2e-10 41.5 0.4 1.2e-10 41.5 0.4 3.3 3 0 0 3 3 3 1 HAMP domain TMP_2 PF06791.13 AAG07095.1 - 8.5e-07 28.8 28.6 0.00034 20.3 13.2 3.3 2 1 1 3 3 3 2 Prophage tail length tape measure protein MSP1_C PF07462.11 AAG07095.1 - 0.019 13.7 2.1 0.035 12.8 2.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AI-2E_transport PF01594.16 AAG07095.1 - 0.055 12.6 1.2 0.34 10.0 0.1 2.6 3 0 0 3 3 3 0 AI-2E family transporter DUF4229 PF14012.6 AAG07095.1 - 0.063 13.4 0.3 0.063 13.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Peptidase_S64 PF08192.11 AAG07095.1 - 0.15 10.5 4.8 0.23 9.9 4.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 Fib_alpha PF08702.10 AAG07095.1 - 0.22 11.7 6.9 2 8.6 0.2 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Mce4_CUP1 PF11887.8 AAG07095.1 - 0.7 9.3 5.2 3 7.2 1.5 2.6 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF1664 PF07889.12 AAG07095.1 - 0.86 9.6 15.5 0.47 10.5 0.7 4.3 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) Sugar_tr PF00083.24 AAG07096.1 - 2.4e-35 122.3 29.6 8.2e-31 107.3 21.2 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAG07096.1 - 1.5e-23 83.3 34.8 1.5e-23 83.3 34.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2721 PF11026.8 AAG07096.1 - 0.17 11.7 0.1 0.17 11.7 0.1 3.2 5 1 1 6 6 6 0 Protein of unknown function (DUF2721) GMC_oxred_N PF00732.19 AAG07097.1 - 1.3e-75 254.6 0.0 1.6e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AAG07097.1 - 2.9e-39 134.9 0.0 4.4e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 AAG07097.1 - 1.7e-06 27.4 0.1 0.0061 15.7 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 AAG07097.1 - 3.2e-05 23.7 4.1 0.00056 19.6 4.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAG07097.1 - 3.5e-05 23.0 0.1 6.2e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAG07097.1 - 0.00095 19.3 0.1 0.005 17.0 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AAG07097.1 - 0.022 14.0 0.0 0.92 8.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAG07097.1 - 0.043 13.1 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG07097.1 - 0.044 12.5 0.0 0.1 11.3 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 AAG07097.1 - 0.049 12.9 0.1 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain PepSY_2 PF13670.6 AAG07097.1 - 0.15 12.1 0.2 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain LysR_substrate PF03466.20 AAG07098.1 - 2e-36 125.3 6.6 3.4e-36 124.6 6.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07098.1 - 5.5e-15 55.1 0.4 1.1e-14 54.1 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_50 PF18024.1 AAG07098.1 - 0.0065 16.1 1.2 0.029 14.0 1.1 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain DUF533 PF04391.12 AAG07099.1 - 1.6e-66 223.3 6.2 2.6e-66 222.6 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF533) TerB PF05099.13 AAG07099.1 - 0.011 15.7 1.5 0.02 14.8 0.1 2.0 2 1 0 2 2 2 0 Tellurite resistance protein TerB NAD_binding_8 PF13450.6 AAG07100.1 - 2.2e-12 47.0 0.2 6e-12 45.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAG07100.1 - 3.6e-07 30.1 0.2 1e-06 28.6 0.0 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG07100.1 - 0.0001 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 AAG07100.1 - 0.00023 20.4 0.1 0.00055 19.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAG07100.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG07100.1 - 0.081 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TAT_signal PF10518.9 AAG07100.1 - 0.083 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Pyr_redox PF00070.27 AAG07100.1 - 0.091 13.3 0.0 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG07100.1 - 0.16 11.0 0.1 0.27 10.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MCRA PF06100.11 AAG07100.1 - 0.2 10.4 0.0 0.43 9.3 0.1 1.4 2 0 0 2 2 2 0 MCRA family HI0933_like PF03486.14 AAG07100.1 - 0.27 9.9 0.0 0.41 9.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Response_reg PF00072.24 AAG07101.1 - 3.2e-23 82.0 0.1 4.7e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG07101.1 - 5.3e-13 48.3 0.0 9.1e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AAG07101.1 - 0.00011 21.6 0.3 0.00024 20.6 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AAG07101.1 - 0.0038 17.0 0.1 0.0086 15.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAG07101.1 - 0.02 14.6 0.5 0.039 13.6 0.5 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 WG_beta_rep PF14903.6 AAG07103.1 - 2.1e-19 69.5 7.3 0.00046 20.4 0.8 9.2 10 0 0 10 10 10 6 WG containing repeat FKBP_C PF00254.28 AAG07104.1 - 2.9e-32 110.9 0.0 3.5e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MFS_1 PF07690.16 AAG07105.1 - 9.2e-33 113.6 69.9 6.1e-28 97.7 53.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG07105.1 - 1.9e-08 33.6 9.9 1.9e-08 33.6 9.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AAG07105.1 - 5e-06 26.1 41.9 6.6e-06 25.6 41.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AAG07105.1 - 0.00069 18.0 5.2 0.00069 18.0 5.2 3.3 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 AAG07105.1 - 1.2 7.9 17.5 0.26 10.1 4.3 3.1 1 1 1 3 3 3 0 MFS_1 like family TetR_C_7 PF14246.6 AAG07108.1 - 2.3e-15 56.6 1.0 5.5e-15 55.4 0.2 2.0 2 1 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AAG07108.1 - 2.2e-14 52.9 0.2 4.7e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Mst1_SARAH PF11629.8 AAG07108.1 - 5 7.3 4.9 23 5.1 0.1 2.9 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Oxidored_FMN PF00724.20 AAG07110.1 - 8e-71 239.1 0.0 9.7e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 AAG07110.1 - 0.017 14.3 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Peripla_BP_6 PF13458.6 AAG07110.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Peptidase_M4_C PF02868.15 AAG07111.1 - 2.8e-37 128.2 1.3 4.9e-37 127.4 1.3 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 AAG07111.1 - 2e-34 119.2 0.4 2e-34 119.2 0.4 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain PepSY PF03413.19 AAG07111.1 - 1.1e-09 38.6 0.2 1.9e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain FTP PF07504.13 AAG07111.1 - 1.1e-08 34.7 0.3 3.6e-06 26.7 0.1 2.7 2 0 0 2 2 2 2 Fungalysin/Thermolysin Propeptide Motif DHHA1 PF02272.19 AAG07112.1 - 2e-29 102.8 0.0 3.4e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 DHHA1 domain RecJ_OB PF17768.1 AAG07112.1 - 2.8e-20 72.6 0.0 4.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 RecJ OB domain DHH PF01368.20 AAG07112.1 - 3.8e-08 33.5 0.0 6.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 DHH family YaeQ PF07152.12 AAG07113.1 - 3.7e-62 209.0 0.0 4.3e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 YaeQ protein PLDc_2 PF13091.6 AAG07114.1 - 3e-28 98.3 0.0 4.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 AAG07114.1 - 7.5e-07 29.0 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 2 FAM83 A-H cIII PF08134.11 AAG07114.1 - 0.0032 17.2 0.1 0.0072 16.0 0.1 1.5 1 0 0 1 1 1 1 cIII protein family PLDc PF00614.22 AAG07114.1 - 0.013 15.7 0.1 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase D Active site motif HOOK PF05622.12 AAG07114.1 - 0.077 11.1 0.4 0.1 10.7 0.4 1.1 1 0 0 1 1 1 0 HOOK protein DUF3686 PF12458.8 AAG07115.1 - 1.7e-199 662.9 0.0 2.4e-199 662.5 0.0 1.2 1 0 0 1 1 1 1 ATPase involved in DNA repair AAA_5 PF07728.14 AAG07115.1 - 1.6e-05 24.9 0.0 6e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAG07115.1 - 3.3e-05 24.3 0.0 0.00011 22.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAG07115.1 - 0.0018 18.1 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAG07115.1 - 0.0029 17.9 3.3 0.0087 16.3 0.0 3.5 3 2 0 3 3 3 1 AAA domain TBCC_N PF16752.5 AAG07115.1 - 0.0073 16.7 6.9 0.013 15.9 0.5 3.5 3 1 0 3 3 3 1 Tubulin-specific chaperone C N-terminal domain AAA_18 PF13238.6 AAG07115.1 - 0.15 12.6 0.2 1.4 9.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF4570 PF15134.6 AAG07115.1 - 4 7.5 5.4 1.7 8.7 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) Flot PF15975.5 AAG07116.1 - 0.0032 17.7 3.1 0.0032 17.7 3.1 6.6 3 1 2 6 6 6 1 Flotillin NfeD PF01957.18 AAG07117.1 - 0.055 13.8 0.0 0.055 13.8 0.0 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding RNA_pol_Rpc4 PF05132.14 AAG07117.1 - 0.16 12.4 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 PspA_IM30 PF04012.12 AAG07118.1 - 6.5e-66 222.1 32.1 7.4e-66 221.9 32.1 1.0 1 0 0 1 1 1 1 PspA/IM30 family Mod_r PF07200.13 AAG07118.1 - 0.00011 22.4 14.0 0.033 14.3 4.0 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein VPS38 PF17649.1 AAG07118.1 - 0.00079 18.4 4.8 0.00079 18.4 4.8 1.5 1 1 1 2 2 2 1 Vacuolar protein sorting 38 EzrA PF06160.12 AAG07118.1 - 0.0011 17.2 6.2 0.0011 17.2 6.2 1.8 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA DUF812 PF05667.11 AAG07118.1 - 0.0034 16.3 11.8 0.0043 16.0 11.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) SHE3 PF17078.5 AAG07118.1 - 0.0035 17.1 3.8 0.0035 17.1 3.8 1.6 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 AAG07118.1 - 0.0052 15.7 19.2 0.96 8.3 1.4 2.1 1 1 0 1 1 1 1 Spc7 kinetochore protein CorA PF01544.18 AAG07118.1 - 0.0064 15.8 2.2 0.0064 15.8 2.2 1.7 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein Laminin_II PF06009.12 AAG07118.1 - 0.011 15.8 2.5 0.011 15.8 2.5 3.0 1 1 2 3 3 3 0 Laminin Domain II MscS_porin PF12795.7 AAG07118.1 - 0.021 14.3 25.0 1 8.9 1.2 3.2 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain pRN1_helical PF13010.6 AAG07118.1 - 0.022 14.7 1.4 0.036 14.0 0.6 1.8 1 1 1 2 2 2 0 Primase helical domain DUF1664 PF07889.12 AAG07118.1 - 0.031 14.3 2.3 0.031 14.3 2.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.11 AAG07118.1 - 0.036 14.2 13.7 0.12 12.4 5.8 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc29 PF17082.5 AAG07118.1 - 0.047 13.5 2.5 0.058 13.2 2.5 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 DASH_Duo1 PF08651.10 AAG07118.1 - 0.058 13.2 2.5 0.14 12.0 0.2 2.6 3 0 0 3 3 2 0 DASH complex subunit Duo1 GCP_N_terminal PF17681.1 AAG07118.1 - 0.081 12.5 2.1 0.095 12.3 2.1 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal FAM76 PF16046.5 AAG07118.1 - 0.087 12.2 13.0 1.2 8.4 0.9 2.0 1 1 1 2 2 2 0 FAM76 protein Prominin PF05478.11 AAG07118.1 - 0.088 10.8 3.5 0.13 10.2 3.5 1.3 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 AAG07118.1 - 0.12 12.5 5.6 0.45 10.5 2.7 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Wtap PF17098.5 AAG07118.1 - 0.12 12.3 14.1 0.03 14.3 7.5 2.9 1 1 0 2 2 2 0 WTAP/Mum2p family DUF2730 PF10805.8 AAG07118.1 - 0.14 12.2 5.1 0.12 12.5 0.8 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 AAG07118.1 - 0.16 12.3 9.6 0.75 10.1 3.1 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 AAG07118.1 - 0.17 9.8 6.0 0.19 9.6 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family USP8_interact PF08941.10 AAG07118.1 - 0.22 11.3 6.2 0.045 13.6 1.2 2.1 2 1 0 2 2 2 0 USP8 interacting Tropomyosin_1 PF12718.7 AAG07118.1 - 0.23 11.6 17.1 0.26 11.4 13.3 2.2 1 1 1 2 2 2 0 Tropomyosin like DNase_NucA_NucB PF14040.6 AAG07118.1 - 0.25 11.7 2.6 0.33 11.3 1.1 1.9 1 1 0 2 2 2 0 Deoxyribonuclease NucA/NucB FlaC_arch PF05377.11 AAG07118.1 - 0.26 11.7 4.6 1.9 8.9 0.4 3.8 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 AAG07118.1 - 0.44 10.6 12.7 0.063 13.4 7.5 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PhoU PF01895.19 AAG07118.1 - 0.44 11.0 6.4 0.27 11.7 2.4 2.7 1 1 1 2 2 2 0 PhoU domain Fib_alpha PF08702.10 AAG07118.1 - 0.59 10.3 8.9 0.22 11.7 3.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 AAG07118.1 - 0.64 10.5 12.0 6 7.4 7.9 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 SIKE PF05769.11 AAG07118.1 - 0.73 9.7 14.5 9.4 6.1 9.8 2.5 1 1 1 2 2 2 0 SIKE family Cortex-I_coil PF09304.10 AAG07118.1 - 0.74 10.1 14.3 0.043 14.0 4.6 3.0 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF724 PF05266.14 AAG07118.1 - 0.74 9.6 13.4 0.06 13.2 6.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Med9 PF07544.13 AAG07118.1 - 0.8 9.8 8.0 0.14 12.3 1.2 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LMBR1 PF04791.16 AAG07118.1 - 0.82 8.5 5.4 0.95 8.3 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Fez1 PF06818.15 AAG07118.1 - 1.8 9.0 18.0 8 6.9 18.2 1.8 1 1 0 1 1 1 0 Fez1 zf-ZPR1 PF03367.13 AAG07118.1 - 2.5 7.9 4.9 2.9 7.7 2.5 2.0 1 1 2 3 3 3 0 ZPR1 zinc-finger domain DUF4407 PF14362.6 AAG07118.1 - 2.7 7.3 25.5 0.17 11.2 17.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 AAG07118.1 - 2.7 8.6 9.1 6.1 7.5 6.9 2.5 2 1 1 3 3 2 0 Syntaxin 6, N-terminal Mt_ATP-synt_D PF05873.12 AAG07118.1 - 2.9 7.7 6.3 12 5.7 6.1 2.2 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Sec20 PF03908.13 AAG07118.1 - 3 7.8 5.5 6 6.8 1.5 2.9 2 2 2 4 4 3 0 Sec20 RasGAP_C PF03836.15 AAG07118.1 - 3.9 7.6 8.8 1 9.5 3.7 2.2 1 1 1 2 2 2 0 RasGAP C-terminus DUF5339 PF17274.2 AAG07118.1 - 4.3 8.3 9.7 11 7.0 0.4 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5339) Exonuc_VII_L PF02601.15 AAG07118.1 - 4.4 6.8 14.8 7.6 6.0 14.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 AAG07118.1 - 4.8 7.9 7.5 2.9 8.6 3.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 AAG07118.1 - 4.9 6.2 18.4 1.2 8.1 10.7 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 AAG07118.1 - 5.2 5.6 12.7 3.6 6.1 7.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A AAA_13 PF13166.6 AAG07118.1 - 10 4.7 15.3 16 3.9 15.3 1.5 1 1 0 1 1 1 0 AAA domain DUF2170 PF09938.9 AAG07119.1 - 5e-51 172.0 0.0 5.6e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2170) CoA_transf_3 PF02515.17 AAG07120.1 - 2.7e-121 405.2 0.0 3.1e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Chlorophyllase2 PF12740.7 AAG07121.1 - 4.3e-09 35.7 0.5 1.3e-08 34.1 0.5 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 AAG07121.1 - 5.4e-05 22.4 0.6 0.00015 20.9 0.6 1.7 1 1 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 AAG07121.1 - 0.0086 14.6 0.2 1.9 6.9 0.1 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 AAG07121.1 - 0.028 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG07121.1 - 0.039 13.2 0.6 11 5.2 0.0 3.1 3 0 0 3 3 3 0 Serine aminopeptidase, S33 AXE1 PF05448.12 AAG07121.1 - 0.053 12.2 0.8 12 4.4 0.1 3.0 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 AAG07121.1 - 0.12 11.8 0.2 10 5.5 0.1 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family Thr_synth_N PF14821.6 AAG07122.1 - 5.9e-29 100.1 0.0 3e-28 97.8 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 AAG07122.1 - 6.2e-26 91.5 0.0 1.1e-24 87.4 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Homoserine_dh PF00742.19 AAG07123.1 - 3.7e-64 215.8 0.2 9.7e-64 214.4 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 AAG07123.1 - 1.8e-25 89.9 0.4 3.3e-25 89.0 0.4 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 AAG07123.1 - 5.7e-17 61.2 0.3 4.1e-16 58.5 0.1 2.3 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AAG07123.1 - 6.2e-05 23.5 0.1 0.00017 22.1 0.1 1.7 1 0 0 1 1 1 1 ACT domain Sacchrp_dh_NADP PF03435.18 AAG07123.1 - 0.0053 17.0 0.3 0.012 15.9 0.3 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ACT_7 PF13840.6 AAG07123.1 - 0.01 15.6 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 ACT domain GFO_IDH_MocA PF01408.22 AAG07123.1 - 0.037 14.9 0.2 0.092 13.6 0.2 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ACT_6 PF13740.6 AAG07123.1 - 0.038 14.0 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 ACT domain DUF2478 PF10649.9 AAG07123.1 - 0.063 12.9 0.2 7.5 6.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) DXP_reductoisom PF02670.16 AAG07123.1 - 0.065 13.9 1.2 0.16 12.7 0.2 2.3 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Thioredoxin_2 PF13098.6 AAG07124.1 - 6.1e-27 94.2 0.1 1.1e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 AAG07124.1 - 2.3e-18 65.4 0.1 4.5e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus DSBA PF01323.20 AAG07124.1 - 3.8e-11 43.1 0.5 9.2e-05 22.3 0.0 3.1 2 1 1 3 3 3 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AAG07124.1 - 5.3e-10 39.7 0.2 3.7e-05 23.9 0.2 2.3 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 AAG07124.1 - 0.01 15.9 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin PF00085.20 AAG07124.1 - 0.019 15.0 0.7 8.5 6.4 0.1 2.6 2 1 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 AAG07124.1 - 0.03 14.5 0.3 0.12 12.6 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin LYTB PF02401.18 AAG07124.1 - 0.045 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 LytB protein Phage_integrase PF00589.22 AAG07125.1 - 4.4e-52 176.3 0.0 5.5e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAG07125.1 - 5.5e-20 71.5 1.2 4.2e-19 68.6 0.0 2.5 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAG07125.1 - 6.9e-10 39.3 0.0 2.4e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AAG07125.1 - 0.0034 17.7 0.0 0.0067 16.7 0.0 1.4 1 0 0 1 1 1 1 Phage integrase SAM-like domain Na_H_Exchanger PF00999.21 AAG07126.1 - 1.2e-36 126.4 41.6 1.5e-36 126.0 41.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AAG07126.1 - 9.8e-06 25.8 0.0 1.7e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain FumaraseC_C PF10415.9 AAG07127.1 - 0.0011 19.3 0.1 0.82 10.1 0.1 2.9 1 1 1 2 2 2 2 Fumarase C C-terminus T2SSE_N PF05157.15 AAG07127.1 - 0.0024 18.1 2.1 0.011 16.0 0.3 2.3 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain DUF2949 PF11165.8 AAG07127.1 - 0.22 11.9 1.9 4.1 7.8 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF2949) 4HBT PF03061.22 AAG07128.1 - 1.9e-17 63.4 0.1 2.7e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAG07128.1 - 0.0029 18.1 0.0 0.0034 17.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Ribosomal_L19 PF01245.20 AAG07129.1 - 2.7e-49 165.7 2.7 3e-49 165.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 tRNA_m1G_MT PF01746.21 AAG07130.1 - 1.6e-64 217.2 0.0 1.8e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RimM PF01782.18 AAG07131.1 - 1.1e-26 92.8 0.0 2.2e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 AAG07131.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 PRC-barrel domain Ribosomal_S16 PF00886.19 AAG07132.1 - 2.2e-24 85.3 0.0 2.7e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 SRP54 PF00448.22 AAG07133.1 - 1.9e-74 249.5 1.0 3.7e-74 248.6 1.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AAG07133.1 - 1.7e-32 112.0 3.9 1.7e-32 112.0 3.9 3.0 4 0 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.19 AAG07133.1 - 1.9e-21 76.0 1.1 1.9e-21 76.0 1.1 2.6 3 0 0 3 3 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AAG07133.1 - 2.6e-07 30.7 0.0 1.3e-06 28.5 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AAG07133.1 - 1.1e-06 28.1 0.1 2.3e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 AAG07133.1 - 0.00025 21.3 0.0 0.00087 19.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain cobW PF02492.19 AAG07133.1 - 0.00035 20.2 0.6 0.0016 18.1 0.6 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 AAG07133.1 - 0.00054 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AAG07133.1 - 0.00094 19.4 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG07133.1 - 0.0026 17.5 1.9 0.0077 16.0 1.9 1.9 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.6 AAG07133.1 - 0.0026 17.7 0.4 0.0083 16.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAG07133.1 - 0.0073 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 AAG07133.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 AAG07133.1 - 0.021 14.1 0.1 0.046 12.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thymidylate_kin PF02223.17 AAG07133.1 - 0.025 14.2 0.2 0.075 12.7 0.2 1.8 1 0 0 1 1 1 0 Thymidylate kinase ABC_tran PF00005.27 AAG07133.1 - 0.026 15.0 0.0 0.36 11.3 0.0 2.6 2 2 0 2 2 2 0 ABC transporter ParA PF10609.9 AAG07133.1 - 0.026 14.0 0.1 0.086 12.3 0.1 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase T2SSE PF00437.20 AAG07133.1 - 0.027 13.6 0.0 0.063 12.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein 6PF2K PF01591.18 AAG07133.1 - 0.027 13.8 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DnaB_C PF03796.15 AAG07133.1 - 0.029 13.7 0.1 0.075 12.4 0.1 1.7 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 AAG07133.1 - 0.035 13.5 0.1 0.16 11.3 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AAG07133.1 - 0.052 13.9 0.1 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAG07133.1 - 0.059 13.5 1.9 0.24 11.5 0.6 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 AAG07133.1 - 0.087 12.8 0.2 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 AAG07133.1 - 0.091 13.2 5.2 0.1 13.0 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 AAG07133.1 - 0.12 12.9 0.1 0.43 11.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF3142 PF11340.8 AAG07133.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) NTPase_1 PF03266.15 AAG07133.1 - 0.14 12.1 0.9 2.8 7.8 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 AAG07133.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 AAG07133.1 - 0.18 11.6 1.8 1.4 8.7 1.8 2.2 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 AAG07133.1 - 0.52 9.4 5.9 0.28 10.3 0.1 2.9 3 0 0 3 3 3 0 Anion-transporting ATPase ResIII PF04851.15 AAG07133.1 - 0.98 9.4 3.3 3 7.8 0.2 2.7 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit SRPRB PF09439.10 AAG07133.1 - 1.1 8.6 3.9 9.8 5.6 0.8 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 AAG07133.1 - 7.3 6.1 9.0 7.8 6.0 3.9 3.3 3 1 0 3 3 3 0 AAA domain Cytochrom_C_asm PF01578.20 AAG07134.1 - 2.2e-41 142.0 21.4 2.8e-41 141.6 21.4 1.1 1 0 0 1 1 1 1 Cytochrome C assembly protein DUF21 PF01595.20 AAG07135.1 - 2.6e-37 128.2 0.2 3.8e-37 127.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AAG07135.1 - 4e-15 55.6 0.0 1e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AAG07135.1 - 3e-14 53.2 2.0 2.2e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain EcpB_C PF18649.1 AAG07135.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 EcpB C-terminal domain DUF393 PF04134.12 AAG07135.1 - 0.11 13.9 0.2 0.33 12.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF393 Sugar_tr PF00083.24 AAG07136.1 - 5.6e-37 127.7 23.1 1.8e-24 86.4 7.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAG07136.1 - 7.1e-31 107.4 73.9 7.3e-22 77.8 44.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAG07136.1 - 5.6e-06 25.2 25.8 0.0005 18.7 14.9 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Lipase_GDSL_2 PF13472.6 AAG07137.1 - 3.8e-16 60.0 0.0 5e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AAG07137.1 - 0.00083 19.4 0.0 0.0017 18.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 AAG07137.1 - 0.0039 16.4 0.0 0.0052 16.0 0.0 1.1 1 0 0 1 1 1 1 OSK domain ATP-grasp PF02222.22 AAG07138.1 - 5.5e-55 185.6 0.0 8.7e-55 184.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAG07138.1 - 2e-06 27.4 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 AAG07138.1 - 3.3e-06 26.8 0.0 8.9e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AAG07138.1 - 6.1e-05 23.1 0.0 0.00015 21.8 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Epimerase PF01370.21 AAG07138.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 AAG07138.1 - 0.0002 20.8 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AAG07138.1 - 0.012 16.2 0.2 0.069 13.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AAG07138.1 - 0.029 14.6 0.2 0.098 12.9 0.1 1.9 1 1 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 AAG07138.1 - 0.044 13.0 0.1 0.07 12.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 AAG07138.1 - 0.055 12.8 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 ThiF family ATP-grasp_4 PF13535.6 AAG07138.1 - 0.055 13.1 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain LAL_C2 PF18603.1 AAG07138.1 - 0.09 12.9 0.8 0.09 12.9 0.8 2.5 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 ApbA PF02558.16 AAG07138.1 - 0.14 11.8 0.1 1.1 8.8 0.0 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF1289 PF06945.13 AAG07139.1 - 6.5e-19 67.5 3.6 7.5e-19 67.3 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) VP7 PF00434.18 AAG07139.1 - 0.098 11.8 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Glycoprotein VP7 Hexapep PF00132.24 AAG07140.1 - 2.9e-16 58.5 8.1 7e-09 35.1 3.3 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAG07140.1 - 0.0001 22.0 8.1 0.011 15.4 5.2 3.2 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase NUDIX PF00293.28 AAG07141.1 - 4.4e-11 42.9 0.0 6.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MamL-1 PF09596.10 AAG07141.1 - 0.079 13.2 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 MamL-1 domain Nudix_N_2 PF14803.6 AAG07142.1 - 2.3e-17 62.6 2.5 3.9e-17 61.8 2.5 1.4 1 0 0 1 1 1 1 Nudix N-terminal NUDIX PF00293.28 AAG07142.1 - 6e-15 55.5 0.1 8.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain DZR PF12773.7 AAG07142.1 - 0.022 14.8 0.4 0.037 14.1 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RRN7 PF11781.8 AAG07142.1 - 0.14 11.8 4.4 1 9.1 4.4 2.2 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-NADH-PPase PF09297.11 AAG07142.1 - 0.47 10.1 5.3 0.93 9.2 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain YkuD PF03734.14 AAG07143.1 - 1.1e-18 68.1 0.0 1.4e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain YkuD_2 PF13645.6 AAG07143.1 - 0.22 11.0 0.0 0.32 10.4 0.0 1.5 1 1 0 1 1 1 0 L,D-transpeptidase catalytic domain UTRA PF07702.13 AAG07144.1 - 1.6e-33 115.5 0.0 2.4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAG07144.1 - 3.7e-17 61.7 0.1 1e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 AAG07144.1 - 8.4e-05 22.2 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain TrmB PF01978.19 AAG07144.1 - 0.0033 17.3 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB RP-C PF03428.13 AAG07144.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain Rrf2 PF02082.20 AAG07144.1 - 0.024 15.0 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 AAG07144.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 HTH domain Fe_dep_repress PF01325.19 AAG07144.1 - 0.031 14.5 0.0 0.086 13.0 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 AAG07144.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4423 PF14394.6 AAG07144.1 - 0.088 12.5 0.0 0.27 10.9 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4423) Amidohydro_1 PF01979.20 AAG07145.1 - 4.8e-12 45.8 0.0 6.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG07145.1 - 9.8e-05 22.0 5.6 0.017 14.6 0.1 2.7 2 1 1 3 3 3 2 Amidohydrolase family HTH_31 PF13560.6 AAG07145.1 - 0.056 13.8 0.4 0.3 11.5 0.3 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain SIS PF01380.22 AAG07146.1 - 1.1e-32 112.6 0.2 7.2e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 AAG07146.1 - 0.023 14.7 0.4 2.4 8.2 0.0 3.4 3 2 1 4 4 4 0 SIS domain PEP-utilizers_C PF02896.18 AAG07147.1 - 9.4e-95 317.1 0.0 1.4e-94 316.5 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PTS_EIIA_1 PF00358.20 AAG07147.1 - 7.8e-41 138.8 0.0 4.2e-40 136.4 0.0 2.1 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PEP-utilisers_N PF05524.13 AAG07147.1 - 8.7e-21 74.3 0.2 8.7e-21 74.3 0.2 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AAG07147.1 - 4e-18 64.9 0.7 8.8e-18 63.8 0.7 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PTS-HPr PF00381.19 AAG07147.1 - 5.9e-18 64.9 0.5 1.8e-17 63.4 0.5 1.9 1 0 0 1 1 1 1 PTS HPr component phosphorylation site PTS_EIIC PF02378.18 AAG07148.1 - 2.1e-72 243.9 22.1 3e-72 243.4 22.1 1.2 1 0 0 1 1 1 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 AAG07148.1 - 7e-16 57.4 1.4 1.1e-08 34.4 0.5 2.5 2 0 0 2 2 2 2 phosphotransferase system, EIIB CutA1 PF03091.15 AAG07149.1 - 0.0047 16.8 0.1 0.0064 16.3 0.1 1.2 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein GATase_5 PF13507.6 AAG07150.1 - 3.1e-106 354.2 0.0 4.5e-106 353.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 AAG07150.1 - 4.3e-49 166.6 0.7 6.4e-31 107.6 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 AAG07150.1 - 8.5e-41 138.6 0.0 1.5e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 AAG07150.1 - 3.3e-23 82.0 0.1 8.9e-23 80.6 0.1 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain SBP_bac_3 PF00497.20 AAG07151.1 - 2.6e-27 95.7 0.1 4.8e-27 94.8 0.0 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 SLT PF01464.20 AAG07151.1 - 2.4e-20 72.3 0.0 5e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain NMT1 PF09084.11 AAG07151.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like DUF2239 PF09998.9 AAG07152.1 - 1.7e-80 269.1 2.2 2e-80 269.0 2.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2239) Trp_Tyr_perm PF03222.13 AAG07153.1 - 6e-29 101.3 26.8 8.4e-29 100.8 26.8 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 AAG07153.1 - 4.4e-11 42.1 28.1 2.5e-09 36.4 28.2 2.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein TPPK_C PF12555.8 AAG07153.1 - 0.6 10.2 0.0 0.6 10.2 0.0 5.1 8 0 0 8 8 8 0 Thiamine pyrophosphokinase C terminal MafB19-deam PF14437.6 AAG07154.1 - 2.8e-30 104.9 0.0 3.3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AAG07154.1 - 1.2e-28 99.0 0.0 1.8e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 AAG07154.1 - 7.6e-05 22.8 0.1 0.00012 22.1 0.1 1.5 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC3 PF18771.1 AAG07154.1 - 0.03 14.4 0.0 0.092 12.9 0.0 1.7 2 0 0 2 2 2 0 APOBEC3 SNAD4 PF18750.1 AAG07154.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 AAG07154.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 APOBEC2 Cu-oxidase_3 PF07732.15 AAG07155.1 - 1.6e-41 141.0 0.0 1.4e-34 118.6 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AAG07155.1 - 4.5e-34 117.1 1.8 7.1e-25 87.3 0.2 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 AAG07155.1 - 4.3e-08 33.4 0.0 0.0039 17.3 0.0 3.3 3 1 0 3 3 3 2 Multicopper oxidase RNase_II_C_S1 PF18614.1 AAG07155.1 - 0.057 13.4 0.3 0.48 10.4 0.1 2.5 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain GMP_synt_C PF00958.22 AAG07156.1 - 6.5e-41 138.3 0.0 1.2e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 AAG07156.1 - 3.6e-36 124.7 0.0 5.6e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 AAG07156.1 - 3.1e-10 39.6 0.2 3.5e-08 32.9 0.2 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AAG07156.1 - 5.4e-08 32.8 0.1 5.6e-07 29.5 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 AAG07156.1 - 3.5e-05 22.8 0.1 0.00019 20.4 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 AAG07156.1 - 0.00053 19.5 0.0 0.43 10.1 0.0 2.2 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AAG07156.1 - 0.0021 17.8 0.4 0.0034 17.1 0.4 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 AAG07156.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.19 AAG07156.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 AAG07156.1 - 0.18 11.4 0.2 0.31 10.6 0.2 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) IMPDH PF00478.25 AAG07157.1 - 9.7e-165 547.7 10.8 1.2e-164 547.4 10.8 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AAG07157.1 - 5.8e-19 68.3 0.4 3.6e-10 40.1 0.1 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 AAG07157.1 - 2.3e-11 43.7 21.5 3e-07 30.2 12.7 2.7 3 1 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 AAG07157.1 - 5.2e-06 25.7 10.3 5.2e-06 25.7 10.3 2.5 2 1 1 3 3 3 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AAG07157.1 - 5.6e-05 22.7 6.6 0.37 10.2 0.1 3.3 1 1 1 3 3 3 3 Histidine biosynthesis protein Dus PF01207.17 AAG07157.1 - 0.0039 16.3 3.1 0.38 9.8 0.7 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 AAG07157.1 - 0.02 14.1 3.3 0.089 12.0 3.3 2.3 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 AAG07157.1 - 0.029 13.5 10.1 0.012 14.7 7.4 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.17 AAG07157.1 - 0.16 11.3 5.6 0.13 11.5 2.4 2.2 1 1 0 2 2 2 0 Thiamine monophosphate synthase B12-binding PF02310.19 AAG07157.1 - 0.25 11.4 5.5 0.074 13.1 1.7 2.0 2 0 0 2 2 2 0 B12 binding domain DHO_dh PF01180.21 AAG07157.1 - 0.85 8.8 8.7 0.97 8.6 1.5 2.6 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase ThiG PF05690.14 AAG07157.1 - 1.6 8.0 14.5 0.22 10.8 7.6 2.5 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG DeoC PF01791.9 AAG07157.1 - 4.2 6.9 10.5 0.54 9.8 5.8 1.8 2 1 0 2 2 2 0 DeoC/LacD family aldolase PcrB PF01884.17 AAG07157.1 - 6.8 6.1 11.3 1.3 8.4 1.6 3.3 3 1 1 4 4 4 0 PcrB family GerE PF00196.19 AAG07158.1 - 7.4e-15 54.3 0.0 1.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG07158.1 - 6.7e-07 28.9 0.0 1.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG07158.1 - 2.2e-05 24.1 0.1 0.00018 21.2 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 AAG07158.1 - 0.00011 21.8 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 AAG07158.1 - 0.00015 22.0 0.0 0.0084 16.4 0.0 2.5 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 AAG07158.1 - 0.00053 20.1 0.0 0.033 14.3 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_20 PF12840.7 AAG07158.1 - 0.00097 19.1 0.2 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAG07158.1 - 0.0015 18.0 0.2 0.0051 16.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_40 PF14493.6 AAG07158.1 - 0.0016 18.9 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_30 PF13556.6 AAG07158.1 - 0.0039 17.0 0.1 0.011 15.5 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAG07158.1 - 0.0041 16.5 0.0 0.23 10.9 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.20 AAG07158.1 - 0.0042 16.9 0.0 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAG07158.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 AAG07158.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_29 PF13551.6 AAG07158.1 - 0.02 14.9 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DciA PF05258.12 AAG07158.1 - 0.04 14.3 0.9 0.11 13.0 0.0 2.2 3 0 0 3 3 2 0 Dna[CI] antecedent, DciA DUF2089 PF09862.9 AAG07158.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Phenol_MetA_deg PF13557.6 AAG07159.1 - 1.6e-28 100.3 3.6 1.9e-28 100.0 3.6 1.1 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation MFS_1 PF07690.16 AAG07160.1 - 1.4e-10 40.6 51.2 1.4e-10 40.6 51.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hist_deacetyl PF00850.19 AAG07161.1 - 6.7e-78 262.3 0.0 9.2e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TauE PF01925.19 AAG07162.1 - 4.3e-29 101.8 30.9 5.6e-29 101.5 30.9 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE LysR_substrate PF03466.20 AAG07163.1 - 1.4e-34 119.3 10.7 2.6e-34 118.5 10.7 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07163.1 - 2.3e-22 78.7 0.3 2.3e-22 78.7 0.3 3.0 3 1 1 4 4 4 1 Bacterial regulatory helix-turn-helix protein, lysR family Exonuc_VII_L PF02601.15 AAG07164.1 - 5.9e-100 334.8 0.5 7.4e-100 334.4 0.5 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 AAG07164.1 - 1.9e-28 98.5 0.0 3.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 AAG07164.1 - 2.1e-10 40.4 0.0 4.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ABC_sub_bind PF04392.12 AAG07164.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein DUF2064 PF09837.9 AAG07164.1 - 0.92 9.3 5.9 3.4 7.5 0.5 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2064) LysR_substrate PF03466.20 AAG07165.1 - 3.1e-38 131.2 4.7 4.8e-38 130.6 4.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07165.1 - 6.7e-20 70.8 0.5 1.3e-19 69.9 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG07165.1 - 0.011 15.5 0.2 0.025 14.4 0.2 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG07165.1 - 0.019 14.8 1.6 0.053 13.4 0.3 2.3 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 AAG07165.1 - 0.022 14.9 1.7 0.075 13.2 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain PBP_like_2 PF12849.7 AAG07165.1 - 0.043 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain HTH_5 PF01022.20 AAG07165.1 - 0.048 13.5 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family P22_Cro PF14549.6 AAG07165.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro DctP PF03480.13 AAG07166.1 - 2.4e-81 273.2 0.0 3.1e-81 272.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 DctQ PF04290.12 AAG07167.1 - 3e-23 82.2 9.3 4.2e-23 81.7 9.3 1.2 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component DctM PF06808.12 AAG07168.1 - 3e-102 342.6 49.4 3.5e-102 342.3 49.4 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component DUF3810 PF12725.7 AAG07168.1 - 2.2 7.5 6.5 56 2.9 6.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) HTH_18 PF12833.7 AAG07169.1 - 4e-19 68.7 2.8 8.7e-19 67.6 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07169.1 - 6.3e-12 45.3 0.5 1.3e-08 34.7 0.3 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 AAG07169.1 - 4.3e-10 39.6 0.0 5.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_11 PF08279.12 AAG07169.1 - 0.24 11.3 1.5 0.66 10.0 0.1 2.3 3 0 0 3 3 3 0 HTH domain HTH_20 PF12840.7 AAG07169.1 - 0.4 10.8 4.1 2.7 8.1 0.2 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Isochorismatase PF00857.20 AAG07170.1 - 8.5e-32 110.7 0.0 9.8e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PCuAC PF04314.13 AAG07172.1 - 3.1e-38 129.9 0.0 3.9e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Copper chaperone PCu(A)C DUF2946 PF11162.8 AAG07173.1 - 1.2e-11 45.3 8.3 1.4e-11 45.0 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Peptidase_M23 PF01551.22 AAG07174.1 - 6.3e-29 100.0 0.0 9.5e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M23 Peptidase_M23_N PF18421.1 AAG07174.1 - 1.1e-28 98.9 0.1 2.1e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M23 N-terminal domain DUF4345 PF14248.6 AAG07175.1 - 4.8e-16 58.7 16.3 5.7e-16 58.5 16.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) CcmH PF03918.14 AAG07175.1 - 0.6 9.4 5.2 1.7 7.9 0.3 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein PepSY_TM PF03929.16 AAG07176.1 - 1e-70 238.7 14.1 1.3e-70 238.3 14.1 1.1 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AAG07176.1 - 4.5e-08 33.5 0.0 0.00076 20.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain DUF4405 PF14358.6 AAG07176.1 - 0.0015 19.0 5.7 0.0015 19.0 5.7 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4405) DUF3188 PF11384.8 AAG07176.1 - 1.6 8.5 4.5 15 5.4 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF4079 PF13301.6 AAG07176.1 - 4.8 7.3 11.5 1.9 8.6 0.2 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF4079) TonB_dep_Rec PF00593.24 AAG07177.1 - 5.1e-50 171.7 21.3 6.8e-50 171.3 21.3 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG07177.1 - 1.1e-12 48.4 0.1 3.1e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG07177.1 - 0.042 12.8 0.0 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Outer membrane protein beta-barrel family DUF2946 PF11162.8 AAG07178.1 - 4.2e-19 69.3 11.0 2.4e-18 66.9 11.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2946) zf_C2H2_6 PF18450.1 AAG07178.1 - 0.014 15.1 1.0 0.027 14.2 1.0 1.5 1 0 0 1 1 1 0 Zinc Finger domain HMGL-like PF00682.19 AAG07179.1 - 1.3e-77 260.9 0.0 2.3e-77 260.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AAG07179.1 - 6.1e-29 100.6 0.0 1.1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF5629 PF18629.1 AAG07180.1 - 2.2e-47 159.6 0.8 2.4e-47 159.5 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5629) EI24 PF07264.11 AAG07181.1 - 0.6 10.3 11.4 1.6 9.0 11.4 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Aldo_ket_red PF00248.21 AAG07182.1 - 2.6e-68 230.4 0.0 3e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF937 PF06078.11 AAG07183.1 - 2.4e-21 76.8 20.8 2.4e-21 76.8 20.8 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF937) CN_hydrolase PF00795.22 AAG07184.1 - 5.4e-32 111.2 0.0 6.1e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aminotran_1_2 PF00155.21 AAG07185.1 - 4.3e-61 207.1 0.0 5.1e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAG07185.1 - 1.3e-09 37.5 0.0 1.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AAG07185.1 - 7.6e-06 25.5 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAG07185.1 - 2.8e-05 22.8 0.0 4.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AAG07185.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase MMR_HSR1 PF01926.23 AAG07186.1 - 3.1e-55 185.1 0.4 5.6e-28 97.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 AAG07186.1 - 1.6e-31 109.0 0.0 9.3e-15 54.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 AAG07186.1 - 3.5e-25 88.1 0.0 6.5e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 AAG07186.1 - 2e-19 69.9 0.6 5.9e-09 35.8 0.2 5.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AAG07186.1 - 2.1e-13 50.7 0.0 0.02 15.0 0.0 4.7 4 1 1 5 5 5 4 Dynamin family AIG1 PF04548.16 AAG07186.1 - 1.3e-10 41.0 0.0 2.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 AAG07186.1 - 1.6e-08 34.6 0.1 0.04 13.8 0.0 3.6 3 1 0 3 3 3 2 RsgA GTPase SRPRB PF09439.10 AAG07186.1 - 2e-08 33.9 0.0 0.0036 16.8 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Roc PF08477.13 AAG07186.1 - 3.8e-07 30.3 0.1 0.026 14.7 0.0 3.4 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AAG07186.1 - 1.3e-06 28.1 0.1 0.019 14.6 0.0 2.8 2 1 0 2 2 2 2 Ras family cobW PF02492.19 AAG07186.1 - 9e-06 25.4 2.5 0.067 12.8 0.0 4.0 2 2 2 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 AAG07186.1 - 2.2e-05 24.3 0.0 0.027 14.2 0.0 3.0 2 2 0 3 3 3 1 AAA domain ABC_tran PF00005.27 AAG07186.1 - 2.5e-05 24.8 0.0 0.094 13.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 AAG07186.1 - 7.7e-05 23.0 0.1 0.52 10.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 AAG07186.1 - 8.8e-05 23.1 0.1 0.1 13.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Arf PF00025.21 AAG07186.1 - 9.5e-05 21.9 0.8 0.12 11.9 0.1 3.8 2 2 0 2 2 2 1 ADP-ribosylation factor family AAA_28 PF13521.6 AAG07186.1 - 0.00017 21.9 0.1 0.24 11.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 AAG07186.1 - 0.0009 19.1 0.0 0.34 10.6 0.0 3.4 3 1 1 4 4 4 1 Conserved hypothetical ATP binding protein TniB PF05621.11 AAG07186.1 - 0.00096 18.6 0.0 0.88 8.9 0.0 2.6 2 0 0 2 2 2 2 Bacterial TniB protein NTPase_1 PF03266.15 AAG07186.1 - 0.001 19.0 0.0 2 8.3 0.0 2.6 2 1 0 2 2 2 2 NTPase NOG1 PF06858.14 AAG07186.1 - 0.0014 18.3 0.5 0.31 10.8 0.0 2.8 3 0 0 3 3 2 1 Nucleolar GTP-binding protein 1 (NOG1) MeaB PF03308.16 AAG07186.1 - 0.0018 17.3 0.1 4.7 6.1 0.0 3.3 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AAG07186.1 - 0.0026 17.9 0.0 2.9 8.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AAG07186.1 - 0.0036 17.7 0.0 3.9 7.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 AAG07186.1 - 0.0043 16.3 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 AAG07186.1 - 0.0053 16.8 0.1 1.4 9.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 AAG07186.1 - 0.0061 16.5 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 AAG07186.1 - 0.0096 15.6 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Nuc_deoxyri_tr2 PF15891.5 AAG07186.1 - 0.022 15.1 0.4 9.8 6.5 0.1 2.5 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like PduV-EutP PF10662.9 AAG07186.1 - 0.022 14.5 0.0 6 6.6 0.0 3.4 2 2 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 AAG07186.1 - 0.04 14.3 0.1 17 5.7 0.0 2.8 2 2 0 2 2 2 0 AAA ATPase domain Nuc_deoxyrib_tr PF05014.15 AAG07186.1 - 0.064 13.3 0.6 5.7 7.0 0.2 2.5 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase Septin PF00735.18 AAG07186.1 - 0.086 12.1 0.0 9.7 5.4 0.0 2.4 2 0 0 2 2 2 0 Septin KTI12 PF08433.10 AAG07186.1 - 0.092 12.2 0.0 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PQQ_2 PF13360.6 AAG07187.1 - 7.2e-57 192.7 18.8 1.1e-50 172.5 8.7 2.8 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AAG07187.1 - 5.5e-27 93.5 25.2 8.7e-06 26.1 0.0 8.1 8 0 0 8 8 8 6 PQQ-like domain PQQ PF01011.21 AAG07187.1 - 4.4e-24 83.2 5.9 5.9e-07 29.1 0.0 5.9 7 0 0 7 7 7 4 PQQ enzyme repeat NUMOD4 PF07463.11 AAG07187.1 - 0.073 13.3 0.0 4 7.7 0.0 2.5 2 0 0 2 2 2 0 NUMOD4 motif TPR_21 PF09976.9 AAG07188.1 - 6.6e-62 208.7 7.7 7.5e-62 208.5 7.7 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 AAG07188.1 - 1.1e-05 25.1 3.2 0.006 16.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAG07188.1 - 2e-05 25.0 11.6 0.0093 16.5 2.5 3.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAG07188.1 - 0.00011 22.7 7.5 0.17 12.5 2.9 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAG07188.1 - 0.00011 22.7 9.2 1.2 10.1 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAG07188.1 - 0.00029 20.8 0.5 0.0092 16.1 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 AAG07188.1 - 0.0012 17.8 0.7 0.0081 15.1 0.3 2.0 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 AAG07188.1 - 0.0036 17.5 3.4 0.44 10.9 0.1 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 AAG07188.1 - 0.0066 16.1 4.7 0.4 10.4 0.1 3.6 4 0 0 4 4 4 1 TPR repeat TPR_10 PF13374.6 AAG07188.1 - 0.0082 16.0 2.3 5.7 6.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAG07188.1 - 0.0088 15.8 0.7 0.082 12.8 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 AAG07188.1 - 0.0097 15.1 1.6 0.02 14.1 0.9 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AAG07188.1 - 0.023 14.9 0.6 0.6 10.4 0.6 2.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AAG07188.1 - 0.04 14.6 8.5 1.1 10.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAG07188.1 - 0.04 14.5 4.7 4 8.3 0.2 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_His PF13393.6 AAG07189.1 - 6.1e-45 153.8 0.0 7.6e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AAG07189.1 - 1.4e-26 93.6 0.0 2.1e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAG07189.1 - 9.2e-09 35.3 0.0 2.8e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 AAG07189.1 - 0.008 15.3 0.0 0.035 13.2 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) GcpE PF04551.14 AAG07190.1 - 9.4e-137 455.8 0.0 1.1e-136 455.6 0.0 1.0 1 0 0 1 1 1 1 GcpE protein DeoC PF01791.9 AAG07190.1 - 0.03 13.9 0.1 1.2 8.6 0.1 2.6 2 1 0 2 2 2 0 DeoC/LacD family aldolase DUF4115 PF13464.6 AAG07191.1 - 9.8e-24 83.3 4.8 1e-23 83.3 0.2 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4115) HTH_25 PF13413.6 AAG07191.1 - 5.4e-22 77.4 0.4 1.5e-21 76.0 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 AAG07191.1 - 6.8e-11 42.3 0.3 2.1e-10 40.8 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG07191.1 - 1.4e-09 37.8 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAG07191.1 - 4.8e-06 26.5 0.7 2.4e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix Sigma70_r4 PF04545.16 AAG07191.1 - 0.0034 16.9 0.0 0.0095 15.4 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 AAG07191.1 - 0.031 14.2 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain LRR_8 PF13855.6 AAG07191.1 - 0.069 12.9 0.5 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 Leucine rich repeat DUF4813 PF16072.5 AAG07191.1 - 2.3 7.8 32.4 3.4 7.2 32.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) TPR_1 PF00515.28 AAG07192.1 - 1.8e-15 56.0 10.1 3e-05 23.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAG07192.1 - 1e-14 53.4 11.0 0.00012 21.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 AAG07192.1 - 7.2e-14 50.8 4.3 0.00011 22.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAG07192.1 - 4.3e-13 49.4 6.3 1.6e-08 34.7 0.2 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAG07192.1 - 2.5e-11 43.1 7.9 0.0018 18.5 0.4 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAG07192.1 - 3.2e-11 42.7 10.5 9e-07 28.5 0.0 4.6 4 2 0 4 4 4 3 TPR repeat TPR_19 PF14559.6 AAG07192.1 - 4.2e-11 43.2 11.0 0.00016 22.1 0.5 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAG07192.1 - 1.3e-10 41.7 11.6 0.0026 18.4 0.5 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AAG07192.1 - 1.1e-09 38.3 6.1 6.6e-05 23.4 0.2 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 AAG07192.1 - 2e-08 33.8 9.3 0.04 13.8 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 AAG07192.1 - 2.1e-06 27.2 4.8 6.5e-05 22.3 2.5 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAG07192.1 - 8.6e-05 22.7 3.9 0.99 9.7 1.1 3.2 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AAG07192.1 - 0.0004 20.8 10.3 0.24 12.1 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 AAG07192.1 - 0.00041 20.4 3.9 0.059 13.5 0.3 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 AAG07192.1 - 0.014 15.7 4.5 0.52 10.7 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAG07192.1 - 0.25 11.4 8.5 4 7.7 0.0 4.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Radical_SAM PF04055.21 AAG07193.1 - 5.5e-16 59.4 0.0 9.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAG07193.1 - 0.003 17.7 0.0 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain NDK PF00334.19 AAG07194.1 - 5.1e-58 194.9 0.1 5.6e-58 194.8 0.1 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Fe-S_assembly PF04384.13 AAG07195.1 - 1.8e-30 105.3 0.6 2e-30 105.2 0.6 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster assembly Fer2 PF00111.27 AAG07196.1 - 4.8e-17 61.7 1.8 5.8e-17 61.4 1.8 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAG07196.1 - 0.00048 20.1 1.3 0.00093 19.2 0.5 1.9 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain S-AdoMet_synt_N PF00438.20 AAG07196.1 - 0.04 14.6 1.9 1.8 9.3 0.1 2.5 1 1 2 3 3 3 0 S-adenosylmethionine synthetase, N-terminal domain HSP70 PF00012.20 AAG07197.1 - 1.5e-182 607.9 0.0 1.8e-182 607.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AAG07197.1 - 5.4e-15 55.0 0.1 4.4e-13 48.7 0.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein MraZ PF02381.18 AAG07197.1 - 0.12 12.3 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like DUF4072 PF13284.6 AAG07197.1 - 0.13 12.7 0.3 0.13 12.7 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) HSCB_C PF07743.13 AAG07198.1 - 4.1e-16 59.2 9.8 4.1e-16 59.2 9.8 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 AAG07198.1 - 3e-07 30.5 0.1 5.9e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Acyl-CoA_dh_2 PF08028.11 AAG07198.1 - 0.072 13.4 6.5 0.081 13.2 2.9 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain AAT PF03417.16 AAG07198.1 - 0.11 12.2 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF2937 PF11157.8 AAG07198.1 - 0.51 10.0 7.2 3.3 7.4 0.9 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2937) Fe-S_biosyn PF01521.20 AAG07199.1 - 1e-24 86.8 0.0 1.1e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NifU_N PF01592.16 AAG07200.1 - 3.3e-58 195.4 0.2 3.8e-58 195.2 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain CO_deh_flav_C PF03450.17 AAG07200.1 - 0.1 12.8 0.1 0.16 12.2 0.1 1.3 1 1 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Aminotran_5 PF00266.19 AAG07201.1 - 4.4e-84 282.6 0.0 5.2e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAG07201.1 - 1.6e-05 24.3 0.0 3.8e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAG07201.1 - 0.00014 21.3 0.1 0.00026 20.4 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAG07201.1 - 0.00026 19.7 0.0 0.00043 18.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AAG07201.1 - 0.0007 19.0 0.1 0.00099 18.5 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Rrf2 PF02082.20 AAG07202.1 - 2.9e-28 98.1 0.2 8.6e-28 96.5 0.2 1.7 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 AAG07202.1 - 0.0098 15.8 1.2 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 MarR family HrcA_DNA-bdg PF03444.15 AAG07202.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_AraC PF00165.23 AAG07202.1 - 0.033 14.3 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_20 PF12840.7 AAG07202.1 - 0.042 13.9 0.1 0.097 12.7 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YjhX_toxin PF09857.9 AAG07202.1 - 0.1 12.6 0.0 0.33 10.9 0.0 1.8 1 1 1 2 2 2 0 Putative toxin of bacterial toxin-antitoxin pair Hexapep PF00132.24 AAG07203.1 - 1.2e-12 47.0 6.1 1.4e-07 30.9 1.5 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAG07203.1 - 7e-05 22.5 7.9 0.00075 19.2 1.5 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 AAG07203.1 - 0.00016 22.0 0.0 0.00046 20.5 0.0 1.7 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal SpoU_methylase PF00588.19 AAG07204.1 - 1e-33 116.5 0.0 1.6e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family Inositol_P PF00459.25 AAG07205.1 - 1e-66 225.2 0.0 1.2e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AAG07205.1 - 0.00093 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Rick_17kDa_Anti PF05433.15 AAG07206.1 - 6.3e-10 38.8 22.3 6.3e-10 38.8 22.3 3.0 2 1 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AAG07206.1 - 9.3e-05 22.1 19.9 9.3e-05 22.1 19.9 2.4 2 1 0 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAG07206.1 - 0.00033 20.6 29.5 0.0045 17.0 8.7 3.2 2 1 1 3 3 3 3 Glycine zipper Hex_IIIa PF02455.16 AAG07206.1 - 0.066 12.0 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF533 PF04391.12 AAG07206.1 - 0.24 10.9 2.5 0.33 10.5 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Bacteriocin_IIc PF10439.9 AAG07206.1 - 3.3 7.9 25.0 0.5 10.5 14.2 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide SecD_SecF PF02355.16 AAG07207.1 - 4.8e-64 215.2 7.4 4.8e-64 215.2 7.4 1.5 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 AAG07207.1 - 9.2e-13 47.2 0.3 1.9e-12 46.2 0.3 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif DUF872 PF05915.12 AAG07207.1 - 0.2 11.9 3.6 5.6 7.2 0.2 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SecD-TM1 PF13721.6 AAG07208.1 - 6e-38 129.4 0.9 6.9e-34 116.4 0.0 3.6 3 0 0 3 3 3 2 SecD export protein N-terminal TM region SecD_SecF PF02355.16 AAG07208.1 - 1.6e-17 63.5 14.4 2.9e-17 62.7 13.8 1.6 2 0 0 2 2 2 1 Protein export membrane protein MMPL PF03176.15 AAG07208.1 - 1.7e-07 30.5 19.4 1.7e-07 30.5 19.4 1.5 2 0 0 2 2 2 1 MMPL family Sec_GG PF07549.14 AAG07208.1 - 1.9e-06 27.1 0.1 4.6e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif ACR_tran PF00873.19 AAG07208.1 - 0.25 8.9 16.9 0.44 8.1 16.9 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Caveolin PF01146.17 AAG07208.1 - 0.97 9.4 3.2 2.3 8.2 3.2 1.6 1 0 0 1 1 1 0 Caveolin YajC PF02699.15 AAG07209.1 - 1.2e-28 98.8 0.1 1.4e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit T2SSM PF04612.12 AAG07209.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF2642 PF10842.8 AAG07209.1 - 0.16 11.8 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) TGT PF01702.18 AAG07210.1 - 7.7e-150 498.9 0.0 1e-149 498.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Queuosine_synth PF02547.15 AAG07211.1 - 3.9e-135 450.1 0.0 4.4e-135 450.0 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein ADH_zinc_N PF00107.26 AAG07211.1 - 0.11 12.5 0.7 22 5.0 0.1 2.9 3 0 0 3 3 3 0 Zinc-binding dehydrogenase EAL PF00563.20 AAG07212.1 - 4.1e-67 226.2 0.0 5.4e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 EAL domain CSS-motif PF12792.7 AAG07212.1 - 1.5e-41 142.2 0.1 2.4e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 CSS motif domain associated with EAL ATP-synt_I PF03899.15 AAG07212.1 - 0.0091 16.4 0.3 4.4 7.7 0.0 2.3 2 0 0 2 2 2 2 ATP synthase I chain RDD PF06271.12 AAG07213.1 - 1.9e-28 99.4 6.7 2.2e-28 99.2 6.7 1.0 1 0 0 1 1 1 1 RDD family Peptidase_M48_N PF16491.5 AAG07213.1 - 4.7 7.1 6.9 6.1 6.7 0.1 2.8 2 1 1 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices LptF_LptG PF03739.14 AAG07214.1 - 1.1e-66 225.1 3.2 1.3e-66 224.9 3.2 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG FtsX PF02687.21 AAG07214.1 - 0.35 11.4 15.2 1.7 9.2 0.1 3.5 3 0 0 3 3 3 0 FtsX-like permease family LptF_LptG PF03739.14 AAG07215.1 - 1.8e-73 247.5 6.9 2e-73 247.3 6.9 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Peptidase_S15 PF02129.18 AAG07216.1 - 1.1e-14 54.7 0.0 1.4e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 AAG07216.1 - 4.7e-10 38.6 0.1 3e-06 26.1 0.1 2.4 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 AAG07216.1 - 8.5e-10 39.6 7.5 1.1e-09 39.2 7.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAG07216.1 - 1e-08 35.1 0.0 6.4e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 AAG07216.1 - 2.5e-08 34.1 0.0 1.6e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 AAG07216.1 - 9.6e-07 28.6 0.0 3.1e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAG07216.1 - 3.6e-06 26.6 0.0 1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAG07216.1 - 7.8e-06 25.3 0.1 2.1e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 AAG07216.1 - 5.4e-05 22.2 0.0 9e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) PAF-AH_p_II PF03403.13 AAG07216.1 - 0.051 12.1 0.1 3.1 6.2 0.1 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF2048 PF09752.9 AAG07216.1 - 0.23 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 HTH_18 PF12833.7 AAG07217.1 - 3.1e-22 78.6 3.8 7.6e-22 77.4 1.8 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07217.1 - 2.5e-08 33.8 0.0 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG07217.1 - 7.5e-07 28.8 0.3 1.3e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AAG07217.1 - 1.5e-06 28.2 0.2 4e-06 26.8 0.2 1.8 1 1 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 AAG07217.1 - 0.052 13.4 0.1 0.076 12.9 0.1 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Peptidase_M17 PF00883.21 AAG07218.1 - 4.5e-127 423.6 0.0 6.4e-127 423.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AAG07218.1 - 1.2e-31 109.1 5.2 1.2e-31 109.1 5.2 1.8 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain DNA_pol3_chi PF04364.13 AAG07219.1 - 4.6e-40 136.9 0.0 5.2e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC tRNA-synt_1 PF00133.22 AAG07221.1 - 1e-220 734.1 0.0 1.4e-219 730.4 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAG07221.1 - 6.4e-44 149.6 0.0 1.2e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 AAG07221.1 - 8e-20 70.9 5.9 1.7e-19 69.9 5.9 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 AAG07221.1 - 1.1e-16 60.5 0.4 2.5e-05 23.2 0.0 4.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AAG07221.1 - 2.6e-09 36.9 0.1 6.1e-08 32.4 0.0 2.3 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 ABC_tran_CTD PF16326.5 AAG07221.1 - 0.0028 17.8 1.5 0.0078 16.4 1.5 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain DUF2312 PF10073.9 AAG07221.1 - 0.11 12.1 1.2 17 5.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF4164 PF13747.6 AAG07221.1 - 3.3 8.0 7.0 2.4 8.5 2.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) ABC_sub_bind PF04392.12 AAG07223.1 - 1.4e-123 411.8 7.0 1.6e-123 411.6 7.0 1.0 1 0 0 1 1 1 1 ABC transporter substrate binding protein Peripla_BP_6 PF13458.6 AAG07223.1 - 8.5e-15 55.2 4.9 1.2e-14 54.8 4.9 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_4 PF13407.6 AAG07223.1 - 3.4e-09 36.7 8.2 0.0001 22.0 0.6 2.2 1 1 0 1 1 1 1 Periplasmic binding protein domain BPD_transp_2 PF02653.16 AAG07224.1 - 2.1e-31 109.1 35.1 2.7e-31 108.7 35.1 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Imm17 PF15562.6 AAG07224.1 - 0.13 12.1 0.1 0.13 12.1 0.1 3.8 3 0 0 3 3 3 0 Immunity protein 17 ABC_tran PF00005.27 AAG07225.1 - 5.4e-26 91.7 0.0 7.8e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAG07225.1 - 1.8e-08 34.1 0.1 1.6e-06 27.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAG07225.1 - 1e-07 32.1 0.1 0.0098 15.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 AAG07225.1 - 0.00087 19.4 0.0 0.0017 18.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 AAG07225.1 - 0.00097 18.8 0.1 0.0028 17.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAG07225.1 - 0.0024 16.7 1.6 0.76 8.5 0.0 2.8 2 1 0 2 2 2 2 Predicted ATPase of the ABC class Dynamin_N PF00350.23 AAG07225.1 - 0.0044 17.1 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 AAG07225.1 - 0.0048 16.8 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_27 PF13514.6 AAG07225.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG07225.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AAG07225.1 - 0.022 15.2 0.2 0.032 14.7 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAG07225.1 - 0.047 14.1 0.0 0.2 12.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AAG07225.1 - 0.19 11.0 0.3 8.4 5.7 0.1 2.1 2 0 0 2 2 2 0 KaiC CitMHS PF03600.16 AAG07226.1 - 4e-71 239.7 59.3 1.4e-56 191.9 29.3 2.1 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 AAG07226.1 - 2.4e-26 91.4 0.2 4.3e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 TrkA-C domain Na_sulph_symp PF00939.19 AAG07226.1 - 4.1e-25 88.8 40.5 1.5e-14 54.0 13.5 3.1 2 1 1 3 3 3 3 Sodium:sulfate symporter transmembrane region DctM PF06808.12 AAG07226.1 - 6.6e-10 38.4 39.7 2.9e-06 26.4 18.2 2.4 2 0 0 2 2 2 2 Tripartite ATP-independent periplasmic transporter, DctM component PaaX PF07848.12 AAG07226.1 - 0.024 14.8 0.8 0.2 11.9 0.3 2.3 2 0 0 2 2 2 0 PaaX-like protein Methyltransf_10 PF05971.12 AAG07227.1 - 8.2e-155 514.6 0.0 9.5e-155 514.4 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 AAG07227.1 - 0.00012 21.7 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 AAG07227.1 - 0.0053 17.5 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG07227.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 AAG07227.1 - 0.19 12.5 0.0 0.43 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ADPrib_exo_Tox PF03496.14 AAG07228.1 - 1.3e-37 129.0 0.0 1.9e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme YopE PF03545.13 AAG07228.1 - 1.3e-32 111.8 3.2 1.3e-32 111.8 3.2 2.0 2 0 0 2 2 2 1 Yersinia virulence determinant (YopE) ART PF01129.18 AAG07228.1 - 4.1e-10 39.3 0.0 1.1e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase CesT PF05932.13 AAG07229.1 - 1.4e-25 89.7 1.6 1.6e-25 89.5 1.6 1.0 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family TPR_9 PF13371.6 AAG07229.1 - 0.021 14.9 1.5 0.045 13.9 1.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Fucose_iso_N1 PF07881.12 AAG07230.1 - 0.17 11.8 0.1 0.22 11.4 0.1 1.1 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain GST_N_3 PF13417.6 AAG07231.1 - 6.8e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG07231.1 - 3.3e-13 49.7 0.0 8.5e-13 48.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAG07231.1 - 1e-06 29.0 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 AAG07231.1 - 0.016 15.9 0.0 0.051 14.3 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 AAG07231.1 - 0.083 12.9 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LysR_substrate PF03466.20 AAG07232.1 - 1.4e-39 135.6 5.5 1.9e-39 135.2 5.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07232.1 - 6.7e-21 74.0 2.3 1.2e-20 73.2 2.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG07232.1 - 0.0054 16.6 0.6 0.024 14.5 0.1 2.3 2 0 0 2 2 2 1 MarR family P22_Cro PF14549.6 AAG07232.1 - 0.0066 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro HTH_30 PF13556.6 AAG07232.1 - 0.022 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_50 PF18024.1 AAG07232.1 - 0.096 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAG07232.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 HTH domain Isochorismatase PF00857.20 AAG07233.1 - 6.4e-26 91.6 0.0 7.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family NMT1_3 PF16868.5 AAG07235.1 - 1.2e-20 74.1 0.0 2.7e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 NMT1-like family NMT1_2 PF13379.6 AAG07235.1 - 4.9e-07 29.7 0.1 1.3e-06 28.3 0.1 1.7 1 1 0 1 1 1 1 NMT1-like family LysR_substrate PF03466.20 AAG07235.1 - 3.1e-06 26.7 0.8 0.0052 16.2 0.2 2.4 1 1 1 2 2 2 2 LysR substrate binding domain Phosphonate-bd PF12974.7 AAG07235.1 - 7e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.7 AAG07235.1 - 0.0042 16.2 0.0 0.0089 15.2 0.0 1.5 1 1 0 1 1 1 1 PBP superfamily domain DUF2312 PF10073.9 AAG07235.1 - 0.042 13.5 0.8 0.096 12.3 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) NA37 PF04245.13 AAG07236.1 - 6.8e-87 291.8 0.0 7.6e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 37-kD nucleoid-associated bacterial protein VIT1 PF01988.19 AAG07238.1 - 2.3e-58 197.6 9.6 2.6e-58 197.4 9.6 1.0 1 0 0 1 1 1 1 VIT family GST_N_3 PF13417.6 AAG07239.1 - 1.6e-12 47.7 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAG07239.1 - 2.1e-08 34.1 4.7 3.7e-08 33.3 0.9 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG07239.1 - 2.3e-07 30.9 0.0 2.4e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AAG07239.1 - 1.8e-06 28.2 0.0 5.8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG07239.1 - 0.00051 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hexapep PF00132.24 AAG07240.1 - 3.7e-12 45.5 1.3 6e-08 32.1 0.5 3.3 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAG07240.1 - 1.7e-05 24.4 1.6 0.021 14.6 0.0 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase GIY-YIG PF01541.24 AAG07241.1 - 1.1e-11 44.8 0.0 1.4e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain GST_N_4 PF17172.4 AAG07242.1 - 1.2e-26 93.3 0.0 2.2e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 AAG07242.1 - 5.5e-17 61.3 0.0 1.9e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AAG07242.1 - 8.2e-13 48.7 0.0 2e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 AAG07242.1 - 5.3e-08 32.8 0.4 1.4e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AAG07242.1 - 3.5e-07 30.5 0.0 1.7e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG07242.1 - 0.0011 19.2 0.0 0.0028 17.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG07242.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAG07242.1 - 0.037 14.2 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SnoaL_2 PF12680.7 AAG07243.1 - 1.2e-17 64.4 4.0 2e-17 63.7 4.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 AAG07243.1 - 7.9e-07 29.4 0.6 1e-06 29.0 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAG07243.1 - 1.8e-06 27.7 0.6 4.3e-06 26.5 0.6 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase LEH PF07858.12 AAG07243.1 - 1.8e-05 24.8 0.2 2.3e-05 24.5 0.2 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain DUF4440 PF14534.6 AAG07243.1 - 2.5e-05 24.6 1.0 3.6e-05 24.1 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 AAG07243.1 - 0.042 14.0 0.5 0.094 12.8 0.5 1.6 1 1 0 1 1 1 0 SnoaL-like domain CDP-OH_P_transf PF01066.21 AAG07244.1 - 5.3e-06 27.1 0.3 5.3e-06 27.1 0.3 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SBP_bac_3 PF00497.20 AAG07245.1 - 5.8e-30 104.4 0.0 7.4e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAG07245.1 - 0.14 12.0 0.0 3.2 7.6 0.0 2.2 1 1 0 2 2 2 0 NMT1/THI5 like Abhydrolase_2 PF02230.16 AAG07246.1 - 1.7e-45 155.5 0.0 2e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 AAG07246.1 - 1.9e-08 33.9 0.3 0.0015 17.8 0.1 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 AAG07246.1 - 1.7e-07 31.1 0.0 8.2e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 AAG07246.1 - 5.3e-06 26.1 0.6 0.0083 15.6 0.1 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AAG07246.1 - 1.5e-05 25.7 6.3 2.8e-05 24.8 6.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 AAG07246.1 - 0.00041 20.2 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 AAG07246.1 - 0.001 19.0 0.4 0.012 15.5 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 AAG07246.1 - 0.0028 17.2 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 AAG07246.1 - 0.063 12.9 0.1 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 Putative esterase PE-PPE PF08237.11 AAG07246.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain AMP-binding PF00501.28 AAG07247.1 - 4.4e-87 292.4 0.0 5.6e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG07247.1 - 6.4e-17 62.3 0.7 1.9e-16 60.8 0.7 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reg_prop PF07494.11 AAG07247.1 - 0.12 12.6 1.5 6.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Two component regulator propeller DEAD PF00270.29 AAG07248.1 - 1e-48 165.4 0.1 1.7e-48 164.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG07248.1 - 2.4e-32 111.6 0.0 5.1e-30 104.1 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 AAG07248.1 - 6.9e-08 32.7 0.0 5.9e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 AAG07248.1 - 3e-05 23.0 0.1 0.013 14.3 0.0 3.3 1 1 2 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 OCD_Mu_crystall PF02423.15 AAG07249.1 - 2.1e-34 118.9 0.0 2.6e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 AAG07249.1 - 0.055 13.5 0.1 0.25 11.4 0.0 2.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AAG07249.1 - 0.089 13.4 0.0 0.23 12.1 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 AAG07250.1 - 1.4e-45 156.4 3.0 1.6e-45 156.2 3.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG07250.1 - 1.8e-05 24.9 0.8 3.7e-05 23.9 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAG07250.1 - 0.0026 16.9 0.4 0.0096 15.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 AAG07250.1 - 0.0037 16.6 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG07250.1 - 0.0053 16.0 0.1 0.0088 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Mqo PF06039.15 AAG07250.1 - 0.0057 15.3 0.0 0.11 11.0 0.0 2.0 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 AAG07250.1 - 0.026 13.8 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DUF4859 PF16151.5 AAG07250.1 - 0.11 12.4 0.3 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4859) Pyr_redox_2 PF07992.14 AAG07250.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PAS_6 PF08348.11 AAG07251.1 - 5e-27 94.1 0.0 7.6e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 YheO-like PAS domain HTH_22 PF13309.6 AAG07251.1 - 2.6e-16 59.4 0.0 4.7e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 AAG07251.1 - 0.02 15.0 0.2 0.081 13.1 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 AAG07251.1 - 0.039 14.0 0.1 0.35 11.0 0.0 2.6 2 2 0 2 2 2 0 Helix-turn-helix domain of resolvase TrmB PF01978.19 AAG07251.1 - 0.048 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 AAG07251.1 - 0.062 13.3 0.0 0.2 11.7 0.0 1.9 1 1 0 1 1 1 0 Winged helix-turn helix HTH_11 PF08279.12 AAG07251.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 HTH domain SBP_bac_3 PF00497.20 AAG07252.1 - 1.9e-62 210.7 0.0 2.1e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG07252.1 - 2e-07 31.2 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAG07252.1 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like Colicin_E5 PF12106.8 AAG07253.1 - 1.2e-38 131.2 1.2 1.2e-38 131.2 1.2 2.1 2 0 0 2 2 2 1 Colicin E5 ribonuclease domain Pyocin_S PF06958.12 AAG07253.1 - 3.1e-36 125.0 5.3 3.1e-36 125.0 5.3 3.4 2 1 1 3 3 3 1 S-type Pyocin Apolipoprotein PF01442.18 AAG07253.1 - 0.073 12.9 42.0 0.28 11.0 26.8 3.2 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF2431 PF10354.9 AAG07253.1 - 0.86 9.9 5.9 0.93 9.7 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2431) L31 PF09784.9 AAG07253.1 - 2.7 8.5 4.4 2.4 8.6 0.3 2.8 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Resolvase PF00239.21 AAG07254.1 - 6.3e-41 139.9 0.7 9.8e-41 139.3 0.7 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 AAG07254.1 - 4.1e-06 26.8 0.4 6.7e-06 26.1 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 AAG07254.1 - 4.9e-06 26.2 0.1 1.2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAG07254.1 - 1.3e-05 25.1 0.1 1.3e-05 25.1 0.1 2.6 2 1 1 3 3 3 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 AAG07254.1 - 2.3e-05 24.6 0.0 4.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAG07254.1 - 0.00024 21.2 0.7 0.001 19.2 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.12 AAG07254.1 - 0.00039 20.3 0.2 0.00083 19.2 0.2 1.5 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_17 PF12728.7 AAG07254.1 - 0.00085 19.5 0.7 0.0021 18.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AAG07254.1 - 0.0065 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase Sigma70_r4_2 PF08281.12 AAG07254.1 - 0.0083 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AAG07254.1 - 0.014 15.2 0.8 0.028 14.2 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_AlpA PF05930.12 AAG07254.1 - 0.017 15.0 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_22 PF13309.6 AAG07254.1 - 0.022 14.8 0.1 0.088 12.9 0.0 2.1 2 0 0 2 2 2 0 HTH domain HTH_8 PF02954.19 AAG07254.1 - 0.033 14.0 0.2 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Sigma70_r4 PF04545.16 AAG07254.1 - 0.034 13.7 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 RuvB_N PF05496.12 AAG07254.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain GP3_package PF16677.5 AAG07254.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 DNA-packaging protein gp3 DUF1492 PF07374.11 AAG07254.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) CENP-B_N PF04218.13 AAG07254.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain rve PF00665.26 AAG07255.1 - 3.7e-08 33.6 0.0 1.1e-07 32.0 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain AAA_22 PF13401.6 AAG07256.1 - 8.2e-05 22.9 0.1 9.7e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 AAA domain Mob_synth_C PF06463.13 AAG07257.1 - 2.2e-38 131.0 0.0 3.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AAG07257.1 - 5.2e-30 105.0 0.0 7.3e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAG07257.1 - 4.8e-08 33.4 0.0 7.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAG07257.1 - 0.0005 20.2 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Rotamase PF00639.21 AAG07258.1 - 3.4e-21 76.0 0.0 6.9e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AAG07258.1 - 1.4e-18 67.5 0.0 2.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAG07258.1 - 4.2e-05 24.4 0.0 8.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Nitrate_red_gam PF02665.14 AAG07259.1 - 2e-76 256.4 13.3 2.3e-76 256.2 13.3 1.0 1 0 0 1 1 1 1 Nitrate reductase gamma subunit Nitrate_red_del PF02613.15 AAG07260.1 - 1.5e-11 44.5 0.3 2.6e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 Nitrate reductase delta subunit Fer4_11 PF13247.6 AAG07261.1 - 3.4e-38 129.8 5.3 8.5e-38 128.5 5.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Nitr_red_bet_C PF14711.6 AAG07261.1 - 2.9e-30 103.8 0.0 6e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 Respiratory nitrate reductase beta C-terminal Fer4_10 PF13237.6 AAG07261.1 - 4.9e-09 36.2 16.1 4e-06 26.8 3.8 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAG07261.1 - 7.7e-08 32.8 17.1 2.9e-05 24.6 4.7 3.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG07261.1 - 2.1e-05 24.4 19.4 0.0056 16.7 0.2 3.9 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 AAG07261.1 - 0.0011 19.1 18.9 0.004 17.3 4.1 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAG07261.1 - 0.0086 15.9 24.9 0.015 15.1 1.9 4.8 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAG07261.1 - 0.012 15.6 21.6 0.033 14.3 1.7 4.0 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_21 PF14697.6 AAG07261.1 - 0.019 15.1 21.1 0.054 13.6 1.1 3.1 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAG07261.1 - 0.037 14.6 0.1 0.037 14.6 0.1 3.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 AAG07261.1 - 0.068 13.7 24.6 0.22 12.1 0.9 4.1 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_17 PF13534.6 AAG07261.1 - 0.13 12.8 14.8 2.1 8.9 0.2 3.8 3 1 0 3 3 3 0 4Fe-4S dicluster domain DUF433 PF04255.14 AAG07261.1 - 0.14 12.0 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Fer4_15 PF13459.6 AAG07261.1 - 0.15 12.8 7.4 5.1 7.9 0.1 3.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_16 PF13484.6 AAG07261.1 - 3.8 8.5 16.6 4.6 8.2 1.5 3.7 2 1 0 3 3 3 0 4Fe-4S double cluster binding domain Molybdopterin PF00384.22 AAG07262.1 - 9.3e-164 545.5 0.0 1.2e-163 545.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAG07262.1 - 5.4e-23 81.1 0.3 1.3e-22 80.0 0.3 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Nitr_red_alph_N PF14710.6 AAG07262.1 - 6.8e-18 64.8 2.3 1.7e-17 63.6 2.3 1.8 1 0 0 1 1 1 1 Respiratory nitrate reductase alpha N-terminal Molybdop_Fe4S4 PF04879.16 AAG07262.1 - 0.0022 18.0 0.0 0.0059 16.6 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain MFS_1 PF07690.16 AAG07263.1 - 1.2e-12 47.4 54.5 1.2e-12 47.4 54.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 AAG07264.1 - 3e-47 161.2 70.0 6.6e-43 147.0 51.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HisKA_3 PF07730.13 AAG07265.1 - 1.8e-17 63.6 1.1 1.8e-17 63.6 1.1 3.8 3 1 0 3 3 3 1 Histidine kinase HAMP PF00672.25 AAG07265.1 - 1.7e-13 50.7 0.1 1.7e-13 50.7 0.1 3.4 5 0 0 5 5 5 1 HAMP domain HATPase_c PF02518.26 AAG07265.1 - 2.7e-09 37.5 0.1 5.1e-08 33.4 0.1 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PilJ PF13675.6 AAG07265.1 - 9.8e-07 28.8 0.3 9.8e-07 28.8 0.3 3.9 3 2 1 4 4 4 1 Type IV pili methyl-accepting chemotaxis transducer N-term HATPase_c_2 PF13581.6 AAG07265.1 - 2.8e-06 27.3 0.0 6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF4184 PF13803.6 AAG07265.1 - 0.14 11.9 0.1 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) Baculo_PEP_C PF04513.12 AAG07265.1 - 0.14 12.2 0.5 15 5.6 0.0 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 AAG07265.1 - 0.15 12.7 0.9 14 6.3 0.2 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Response_reg PF00072.24 AAG07266.1 - 4.9e-31 107.2 0.2 8.6e-31 106.4 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG07266.1 - 6.4e-22 76.9 0.3 1.5e-21 75.7 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG07266.1 - 1.3e-09 37.6 0.2 2.4e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG07266.1 - 2.8e-08 33.1 1.3 5.9e-08 32.1 0.4 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 AAG07266.1 - 0.0011 19.0 0.1 0.0037 17.4 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG07266.1 - 0.002 17.9 0.2 0.0052 16.6 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 AAG07266.1 - 0.0022 17.5 0.2 0.0067 16.0 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AAG07266.1 - 0.0076 16.0 0.3 0.015 15.0 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain KORA PF16509.5 AAG07266.1 - 0.0077 16.5 0.3 0.017 15.4 0.3 1.6 1 0 0 1 1 1 1 TrfB plasmid transcriptional repressor HTH_10 PF04967.12 AAG07266.1 - 0.072 12.9 2.1 1.2 9.0 0.6 2.9 2 1 0 2 2 2 0 HTH DNA binding domain R3H PF01424.22 AAG07266.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 R3H domain DGC PF08859.11 AAG07267.1 - 8.6e-31 106.2 0.1 9.7e-31 106.0 0.1 1.0 1 0 0 1 1 1 1 DGC domain SLC35F PF06027.12 AAG07268.1 - 0.096 12.2 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Solute carrier family 35 Methyltransf_11 PF08241.12 AAG07269.1 - 9.7e-17 61.4 0.0 1.6e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG07269.1 - 5.7e-13 49.4 0.0 9.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG07269.1 - 3.2e-06 27.1 0.1 5.1e-06 26.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG07269.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG07269.1 - 0.00021 22.0 0.0 0.0004 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAG07269.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 AAG07269.1 - 0.075 11.6 0.0 0.083 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase adh_short PF00106.25 AAG07270.1 - 5.2e-45 153.3 0.1 6.4e-45 153.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG07270.1 - 4.4e-36 124.6 0.6 5.6e-36 124.2 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 AAG07270.1 - 7.8e-11 41.9 0.0 2.3e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 AAG07270.1 - 1.7e-08 34.6 0.4 2.8e-08 33.9 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG07270.1 - 2.2e-06 27.3 0.0 4.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAG07270.1 - 8.9e-05 22.5 0.6 8.9e-05 22.5 0.6 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 AAG07270.1 - 0.0024 17.5 0.2 0.0039 16.8 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 AAG07270.1 - 0.0032 16.6 1.5 0.02 14.0 0.2 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.18 AAG07270.1 - 0.006 16.8 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Y_phosphatase2 PF03162.13 AAG07272.1 - 8e-10 38.5 0.0 2.1e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 AAG07272.1 - 8.9e-07 29.1 0.1 9e-06 25.8 0.1 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 AAG07272.1 - 2.2e-06 27.5 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AAG07272.1 - 2.9e-05 23.7 0.0 4.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF442 PF04273.13 AAG07272.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative phosphatase (DUF442) PTPlike_phytase PF14566.6 AAG07272.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Hydrolase_6 PF13344.6 AAG07273.1 - 3.6e-10 39.9 0.0 6.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG07273.1 - 3.7e-08 33.3 0.0 6.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 AAG07273.1 - 6.5e-05 23.3 0.0 0.031 14.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cm_res_leader PF08077.11 AAG07273.1 - 0.12 12.5 0.2 24 5.5 0.0 2.9 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide Na_H_Exchanger PF00999.21 AAG07274.1 - 1.1e-74 251.6 39.9 1.3e-74 251.3 39.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HTH_51 PF18558.1 AAG07274.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain BPD_transp_1 PF00528.22 AAG07275.1 - 8.4e-20 71.3 11.4 8.4e-20 71.3 11.4 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4514 PF14986.6 AAG07275.1 - 1.6 8.8 4.4 0.7 9.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) OpuAC PF04069.12 AAG07276.1 - 8e-69 232.1 0.0 9e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system FliW PF02623.15 AAG07276.1 - 0.092 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 FliW protein BPD_transp_1 PF00528.22 AAG07277.1 - 4e-20 72.3 22.0 6.6e-20 71.6 22.0 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAG07278.1 - 3.5e-34 118.3 0.0 5.7e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter CBS PF00571.28 AAG07278.1 - 1.2e-14 54.4 0.0 1.5e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain AAA_21 PF13304.6 AAG07278.1 - 4.2e-06 26.8 0.0 0.0025 17.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG07278.1 - 0.00013 22.4 0.1 0.0012 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 AAG07278.1 - 0.00055 19.9 0.0 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 AAG07278.1 - 0.0052 16.7 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 AAG07278.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AAG07278.1 - 0.036 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAG07278.1 - 0.037 14.3 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAG07278.1 - 0.044 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AAG07278.1 - 0.045 14.0 0.1 0.51 10.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAG07278.1 - 0.085 13.3 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAG07278.1 - 0.096 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 AAG07278.1 - 0.1 11.7 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 AAG07278.1 - 0.11 13.0 0.1 9.7 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AAG07278.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_11 PF13086.6 AAG07278.1 - 0.22 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAG07278.1 - 0.22 12.0 0.1 0.47 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Biotin_lipoyl_2 PF13533.6 AAG07279.1 - 9.6e-19 67.0 11.5 2.5e-16 59.2 2.4 3.1 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 AAG07279.1 - 5.1e-17 62.5 0.0 3.8e-10 40.4 0.0 2.5 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAG07279.1 - 8.5e-16 57.8 1.7 2.8e-15 56.1 1.7 1.8 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAG07279.1 - 0.00024 20.9 0.1 0.0043 16.9 0.1 2.2 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG07279.1 - 0.00054 19.7 1.1 0.22 11.4 0.4 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme DUF5339 PF17274.2 AAG07279.1 - 0.11 13.4 0.4 0.22 12.4 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5339) PTS_EIIA_1 PF00358.20 AAG07279.1 - 0.15 11.8 0.1 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF4423 PF14394.6 AAG07279.1 - 0.16 11.6 1.2 1.1 8.9 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) FUSC PF04632.12 AAG07280.1 - 1.2e-218 727.9 43.9 1.4e-218 727.7 43.9 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAG07280.1 - 1.5e-10 41.3 10.4 1.5e-10 41.3 10.4 3.1 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AAG07280.1 - 3e-05 24.2 8.8 3e-05 24.2 8.8 2.9 2 1 1 3 3 3 1 Aromatic acid exporter family member 1 DinB_2 PF12867.7 AAG07280.1 - 4.5 7.8 7.5 0.68 10.5 1.3 2.7 2 1 1 3 3 3 0 DinB superfamily ALMT PF11744.8 AAG07280.1 - 5.2 5.8 7.3 8.3 5.1 7.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter OEP PF02321.18 AAG07281.1 - 2.7e-43 148.0 12.5 3.8e-23 82.3 4.9 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein Atg14 PF10186.9 AAG07281.1 - 0.1 11.6 1.0 6 5.8 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LysR_substrate PF03466.20 AAG07282.1 - 2.6e-38 131.5 0.0 3.4e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07282.1 - 5e-20 71.2 3.3 8.6e-20 70.5 3.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family 2-Hacid_dh_C PF02826.19 AAG07283.1 - 2.6e-59 199.6 0.0 6e-59 198.4 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAG07283.1 - 2.7e-28 98.3 0.0 3.1e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAG07283.1 - 0.0032 17.7 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAG07283.1 - 0.023 15.3 0.0 0.1 13.2 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent EamA PF00892.20 AAG07284.1 - 3.9e-26 91.8 34.9 2e-14 53.9 11.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF423 PF04241.15 AAG07284.1 - 0.34 11.1 10.2 2.5 8.3 0.9 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF423) HTH_18 PF12833.7 AAG07285.1 - 2.2e-23 82.3 3.8 3.9e-23 81.5 2.8 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07285.1 - 2.5e-13 49.7 0.0 1.8e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Apelin PF15360.6 AAG07285.1 - 0.14 12.7 0.6 0.81 10.3 0.1 2.4 2 0 0 2 2 2 0 APJ endogenous ligand Sigma70_r4_2 PF08281.12 AAG07286.1 - 3.4e-16 58.6 1.3 4.1e-14 52.0 0.1 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG07286.1 - 1.3e-15 56.9 0.9 2.3e-15 56.1 0.9 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AAG07286.1 - 4.4e-08 33.2 0.0 5.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AAG07286.1 - 4.3e-07 29.3 0.1 1.1e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG07286.1 - 0.00032 20.4 0.1 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 AAG07286.1 - 0.0028 17.2 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAG07286.1 - 0.011 15.5 2.3 0.022 14.6 0.0 2.7 4 0 0 4 4 4 0 IclR helix-turn-helix domain GerE PF00196.19 AAG07286.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family TnsD PF15978.5 AAG07286.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_36 PF13730.6 AAG07286.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FecR PF04773.13 AAG07287.1 - 1.6e-19 70.3 0.0 2.3e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG07287.1 - 1.7e-13 50.2 15.9 4.7e-13 48.8 15.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) TonB_dep_Rec PF00593.24 AAG07288.1 - 4.4e-52 178.5 35.4 6.4e-52 178.0 35.4 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG07288.1 - 5.5e-19 68.7 0.5 1.4e-18 67.4 0.5 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG07288.1 - 9.3e-09 35.0 0.0 3.2e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Secretin and TonB N terminus short domain OMP_b-brl_3 PF14905.6 AAG07288.1 - 1.4e-08 34.2 5.1 6.9e-06 25.3 1.0 2.2 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family Ivy PF08816.11 AAG07289.1 - 1.7e-42 144.3 0.0 2.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Inhibitor of vertebrate lysozyme (Ivy) GTP_EFTU PF00009.27 AAG07290.1 - 1.4e-46 158.5 0.0 2.4e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 AAG07290.1 - 2e-45 153.9 0.0 3.3e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 AAG07290.1 - 1.4e-10 41.4 0.0 3.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 AAG07290.1 - 8.2e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AAG07290.1 - 0.00023 21.2 0.0 0.00052 20.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 AAG07290.1 - 0.018 14.5 0.4 0.63 9.5 0.1 3.1 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit PAAR_motif PF05488.13 AAG07291.1 - 6.7e-19 67.8 8.5 2.1e-15 56.6 0.4 2.6 1 1 2 3 3 3 3 PAAR motif Abhydrolase_6 PF12697.7 AAG07291.1 - 0.0075 16.9 2.3 0.01 16.5 2.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MatB PF16449.5 AAG07291.1 - 0.036 13.9 0.3 0.046 13.5 0.3 1.1 1 0 0 1 1 1 0 Fimbrillin MatB DUF4123 PF13503.6 AAG07292.1 - 7.4e-23 81.4 2.4 9.7e-23 81.0 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4123) Tox-REase-5 PF15648.6 AAG07294.1 - 7.4e-22 77.7 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 5 TonB_N PF16031.5 AAG07294.1 - 8.2 6.9 19.0 1.7 9.2 14.1 2.0 2 0 0 2 2 2 0 TonB polyproline region Imm52 PF15579.6 AAG07295.1 - 1.5e-25 88.9 0.0 2.3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Immunity protein 52 LTD PF00932.19 AAG07296.1 - 1.5e-16 60.7 0.0 6.1e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Lamin Tail Domain Exo_endo_phos PF03372.23 AAG07296.1 - 3.9e-09 36.4 1.0 2.6e-08 33.7 0.2 2.4 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PhoD PF09423.10 AAG07297.1 - 1e-87 294.4 0.1 1.2e-87 294.2 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 AAG07297.1 - 5.9e-18 65.2 0.0 1.3e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Metallophos PF00149.28 AAG07297.1 - 0.11 13.0 0.0 3.5 8.1 0.0 2.9 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase SCP2 PF02036.17 AAG07298.1 - 3.5e-14 53.1 0.0 4.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family MDMPI_C PF07398.11 AAG07298.1 - 0.0023 18.8 3.7 0.0023 18.8 3.7 2.1 1 1 1 2 2 2 1 MDMPI C-terminal domain Peptidase_U32 PF01136.19 AAG07299.1 - 8.2e-12 44.8 0.0 1.3e-11 44.1 0.0 1.3 1 1 0 1 1 1 1 Peptidase family U32 Peptidase_U32 PF01136.19 AAG07300.1 - 2.5e-63 213.3 0.0 3.1e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family U32 MoeA_N PF03453.17 AAG07301.1 - 1.5e-46 158.0 0.0 3.6e-46 156.8 0.0 1.7 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAG07301.1 - 2.2e-22 79.3 0.0 3.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AAG07301.1 - 4.6e-15 55.6 0.0 9.6e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) MoCF_biosynth PF00994.24 AAG07302.1 - 6.7e-31 106.9 0.0 8.3e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain Fer2_4 PF13510.6 AAG07302.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain MoaE PF02391.17 AAG07303.1 - 2.1e-34 118.2 0.0 2.5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 MoaE protein ThiS PF02597.20 AAG07304.1 - 3.1e-19 69.4 0.0 3.5e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 ThiS family TGS PF02824.21 AAG07304.1 - 0.033 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 TGS domain MoaC PF01967.21 AAG07305.1 - 1.4e-57 193.5 0.9 1.6e-57 193.4 0.9 1.0 1 0 0 1 1 1 1 MoaC family PhoH PF02562.16 AAG07306.1 - 1.1e-45 155.7 0.0 1.5e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 AAG07306.1 - 9e-40 136.0 0.0 1.4e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 PIN domain AAA_30 PF13604.6 AAG07306.1 - 2.5e-07 30.6 0.0 7.3e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zot PF05707.12 AAG07306.1 - 4.2e-06 26.5 0.0 0.0015 18.2 0.0 3.1 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 AAG07306.1 - 0.0027 18.1 0.3 0.028 14.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 AAG07306.1 - 0.0058 15.8 0.0 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 AAG07306.1 - 0.0082 15.9 0.1 2.2 7.9 0.0 2.5 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 AAG07306.1 - 0.012 15.4 0.1 4.4 7.0 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_16 PF13191.6 AAG07306.1 - 0.013 15.9 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PIN_9 PF18477.1 AAG07306.1 - 0.014 15.7 0.1 0.42 10.9 0.0 2.5 2 0 0 2 2 2 0 PIN like domain ATPase PF06745.13 AAG07306.1 - 0.039 13.3 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 AAG07306.1 - 0.051 13.8 1.8 0.25 11.6 0.2 2.8 3 1 0 3 3 2 0 AAA domain AAA PF00004.29 AAG07306.1 - 0.12 12.8 0.1 1.2 9.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 AAG07306.1 - 0.18 11.0 0.1 0.41 9.8 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) E1-E2_ATPase PF00122.20 AAG07307.1 - 5.4e-56 189.0 1.1 5.4e-56 189.0 1.1 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AAG07307.1 - 2.8e-42 145.4 1.8 6.2e-42 144.3 1.8 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAG07307.1 - 1.5e-34 118.2 0.1 4.6e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain FeS_assembly_P PF01883.19 AAG07307.1 - 0.0048 17.0 0.8 3.1 8.0 0.0 3.4 3 0 0 3 3 3 2 Iron-sulfur cluster assembly protein Hydrolase_3 PF08282.12 AAG07307.1 - 0.005 16.6 1.2 0.012 15.3 1.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG07307.1 - 0.032 14.6 0.6 0.27 11.6 0.5 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BON PF04972.17 AAG07307.1 - 0.097 13.0 3.2 1.3 9.4 0.7 2.9 2 0 0 2 2 2 0 BON domain BTP PF05232.12 AAG07307.1 - 8.4 6.5 11.1 0.69 10.0 2.2 3.0 3 0 0 3 3 3 0 Chlorhexidine efflux transporter TPR_MalT PF17874.1 AAG07308.1 - 3.9e-23 82.4 15.9 6.8e-23 81.6 15.9 1.3 1 0 0 1 1 1 1 MalT-like TPR region GerE PF00196.19 AAG07308.1 - 5.4e-18 64.3 0.2 1.1e-17 63.4 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_12 PF13424.6 AAG07308.1 - 5.3e-08 33.0 32.7 4e-05 23.8 1.2 5.6 3 1 3 6 6 6 3 Tetratricopeptide repeat AAA_16 PF13191.6 AAG07308.1 - 3.6e-07 30.7 0.9 3.6e-07 30.7 0.9 3.9 4 0 0 4 4 4 1 AAA ATPase domain Sigma70_r4_2 PF08281.12 AAG07308.1 - 4.9e-05 22.9 2.3 0.00025 20.6 0.1 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG07308.1 - 0.0018 18.0 0.5 0.007 16.1 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain TPR_1 PF00515.28 AAG07308.1 - 0.0034 17.2 9.7 0.53 10.2 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAG07308.1 - 0.0055 16.8 1.1 41 4.7 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAG07308.1 - 0.0072 16.8 35.5 0.18 12.3 3.9 7.5 6 2 1 7 7 7 2 Tetratricopeptide repeat Sigma70_r4 PF04545.16 AAG07308.1 - 0.013 15.0 0.1 0.052 13.1 0.1 2.1 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_2 PF07719.17 AAG07308.1 - 0.021 14.9 24.5 1.2 9.4 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat HTH_24 PF13412.6 AAG07308.1 - 0.033 13.7 0.1 0.074 12.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TPR_21 PF09976.9 AAG07308.1 - 0.66 9.6 13.4 0.29 10.8 1.8 3.8 3 1 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 AAG07308.1 - 0.99 9.4 24.5 6.3 6.8 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAG07308.1 - 8.7 7.0 5.8 28 5.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1329 PF07044.11 AAG07309.1 - 1.9e-157 524.2 11.8 2.2e-157 524.0 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) LolA_like PF17131.4 AAG07309.1 - 8.6e-09 35.4 0.6 1.6e-06 28.0 0.3 2.6 2 1 0 2 2 2 1 Outer membrane lipoprotein-sorting protein DUF1302 PF06980.11 AAG07310.1 - 3.7e-231 768.7 7.5 4.2e-231 768.5 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) AMP-binding PF00501.28 AAG07311.1 - 3.1e-89 299.5 0.1 3.8e-89 299.2 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG07311.1 - 6.2e-19 68.8 0.1 1.1e-18 67.9 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 AAG07312.1 - 2.2e-88 296.0 5.3 2.9e-88 295.6 5.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG07312.1 - 3.9e-41 139.5 1.0 5.4e-40 135.9 0.3 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG07312.1 - 0.0043 16.7 6.2 0.011 15.4 0.3 3.4 1 1 2 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AAG07312.1 - 0.034 14.0 0.5 3.9 7.4 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.16 AAG07313.1 - 5.5e-35 120.9 57.5 4.2e-27 95.0 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_18 PF12833.7 AAG07314.1 - 4.9e-22 78.0 4.6 7.9e-22 77.3 0.8 2.5 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07314.1 - 9.5e-12 44.7 0.0 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG07314.1 - 6.3e-05 22.9 6.1 0.00028 20.8 6.1 2.1 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG07314.1 - 0.00031 20.4 0.6 0.00052 19.7 0.6 1.4 1 0 0 1 1 1 1 Cupin domain DUF2474 PF10617.9 AAG07315.1 - 1.4e-18 66.5 12.3 1.7e-18 66.2 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2474) Cyt_bd_oxida_II PF02322.15 AAG07316.1 - 1.3e-103 346.6 31.2 1.4e-103 346.4 31.2 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II GTA_holin_3TM PF11351.8 AAG07316.1 - 0.14 12.7 1.6 0.5 10.9 1.6 2.0 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Cyt_bd_oxida_I PF01654.17 AAG07317.1 - 1e-168 561.3 24.5 1.2e-168 561.1 24.5 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I DUF4235 PF14019.6 AAG07317.1 - 0.0085 16.2 0.5 0.0085 16.2 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4235) Lipoprotein_9 PF03180.14 AAG07318.1 - 1.3e-101 338.6 0.7 1.5e-101 338.4 0.7 1.0 1 0 0 1 1 1 1 NLPA lipoprotein Phosphonate-bd PF12974.7 AAG07318.1 - 1.5e-06 28.0 0.1 0.00024 20.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_11 PF13531.6 AAG07318.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein PRTP PF01366.18 AAG07318.1 - 0.19 9.8 0.2 0.26 9.3 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Sigma54_activat PF00158.26 AAG07319.1 - 5.2e-47 159.7 0.0 7e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG07319.1 - 6e-20 71.8 0.0 1.1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAG07319.1 - 2.5e-06 27.5 0.0 9.9e-06 25.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG07319.1 - 0.00091 18.7 0.0 0.064 12.6 0.0 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AAG07319.1 - 0.001 19.5 1.4 0.0011 19.3 0.2 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 AAG07319.1 - 0.0098 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 AAG07319.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 KaiC ATP-synt_ab PF00006.25 AAG07319.1 - 0.032 13.9 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TilS PF09179.11 AAG07319.1 - 0.07 13.6 3.3 0.23 12.0 0.4 2.6 2 0 0 2 2 2 0 TilS substrate binding domain AAA_19 PF13245.6 AAG07319.1 - 0.07 13.5 0.0 9.6 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 AAG07319.1 - 0.16 11.8 0.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AAG07319.1 - 0.19 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain BCCT PF02028.17 AAG07320.1 - 7.9e-181 601.7 33.2 9.1e-181 601.5 33.2 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter OPT PF03169.15 AAG07321.1 - 4.1e-111 372.6 45.7 5.2e-111 372.2 45.7 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FHIPEP PF00771.20 AAG07321.1 - 0.34 9.3 2.0 0.61 8.5 2.0 1.4 1 0 0 1 1 1 0 FHIPEP family OST3_OST6 PF04756.13 AAG07321.1 - 1 8.6 3.8 0.55 9.5 0.8 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family TauD PF02668.16 AAG07322.1 - 1.9e-67 227.9 0.7 2.2e-67 227.7 0.7 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HD_6 PF18019.1 AAG07322.1 - 0.056 13.6 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 HD domain BPD_transp_1 PF00528.22 AAG07323.1 - 6.5e-26 91.2 15.5 1.4e-25 90.1 15.5 1.5 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component STAS_2 PF13466.6 AAG07323.1 - 0.37 11.2 9.6 0.25 11.7 0.8 3.2 2 1 1 3 3 3 0 STAS domain ABC_tran PF00005.27 AAG07324.1 - 6e-33 114.3 0.0 8.7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07324.1 - 2.4e-07 30.9 0.1 0.004 17.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG07324.1 - 9e-06 26.2 0.9 1.5e-05 25.4 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG07324.1 - 4.7e-05 23.3 0.0 8.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAG07324.1 - 0.00061 20.1 0.4 0.0029 17.9 0.4 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAG07324.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain SbcCD_C PF13558.6 AAG07324.1 - 0.0084 16.3 1.4 0.25 11.6 1.4 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 AAG07324.1 - 0.016 15.4 0.0 0.082 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAG07324.1 - 0.018 15.5 0.0 0.091 13.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAG07324.1 - 0.018 14.8 0.1 0.034 13.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 AAG07324.1 - 0.026 14.0 0.7 3 7.2 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAG07324.1 - 0.042 13.4 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAG07324.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 AAG07324.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 AAG07324.1 - 0.086 12.4 0.1 3.5 7.1 0.1 2.2 1 1 1 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAG07324.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 AAG07324.1 - 0.1 12.5 0.5 0.33 10.9 0.0 2.1 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.21 AAG07324.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 AAG07324.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 AAG07324.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Dynamin family ATPase_2 PF01637.18 AAG07324.1 - 0.2 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 AAG07324.1 - 0.25 11.8 0.0 0.45 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NMT1 PF09084.11 AAG07325.1 - 1.3e-20 74.3 0.0 2e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like OpuAC PF04069.12 AAG07325.1 - 1.4e-18 67.5 0.1 1.9e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_2 PF13379.6 AAG07325.1 - 2.8e-12 46.9 0.3 1.3e-11 44.7 0.2 2.1 1 1 1 2 2 2 1 NMT1-like family Phosphonate-bd PF12974.7 AAG07325.1 - 6e-09 35.9 0.0 9.1e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAG07325.1 - 1e-05 25.1 0.0 6.4e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 DUF4646 PF15496.6 AAG07325.1 - 0.0038 17.8 0.0 0.44 11.2 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4646) NMT1_3 PF16868.5 AAG07325.1 - 0.0084 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Acyl-CoA_dh_N PF02771.16 AAG07326.1 - 2.3e-05 25.0 0.0 0.00014 22.5 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Bac_DNA_binding PF00216.21 AAG07327.1 - 3e-28 97.8 0.2 3.4e-28 97.7 0.2 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAG07327.1 - 6.6e-07 29.5 0.0 7.1e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAG07327.1 - 6e-06 26.0 0.1 1.2e-05 25.1 0.0 1.4 2 0 0 2 2 2 1 CCDC81-like prokaryotic HU domain 2 SSPI PF14098.6 AAG07327.1 - 0.0077 16.4 1.4 0.03 14.5 0.2 2.0 1 1 1 2 2 2 1 Small, acid-soluble spore protein I GntR PF00392.21 AAG07327.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HU-CCDC81_euk_2 PF18289.1 AAG07327.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 SIS_2 PF13580.6 AAG07327.1 - 0.035 14.1 0.1 0.066 13.2 0.0 1.5 1 1 0 1 1 1 0 SIS domain Poly_export PF02563.16 AAG07327.1 - 0.038 14.2 0.2 0.24 11.7 0.0 2.0 1 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein HAD_2 PF13419.6 AAG07328.1 - 1.2e-18 67.8 0.0 3.3e-17 63.2 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG07328.1 - 2.5e-17 63.9 0.0 6.4e-14 52.7 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG07328.1 - 7.5e-11 42.8 1.8 4.3e-10 40.3 1.8 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG07328.1 - 3.9e-07 30.0 0.0 7.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AAG07328.1 - 0.0011 19.0 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase 4HBT_3 PF13622.6 AAG07329.1 - 1.5e-62 212.1 0.2 1.8e-62 211.8 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 AAG07329.1 - 5.7e-41 139.5 0.0 5.4e-31 107.2 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase Nitroreductase PF00881.24 AAG07330.1 - 1e-10 41.9 0.2 5e-05 23.4 0.0 2.6 2 1 0 2 2 2 2 Nitroreductase family Acetyltransf_3 PF13302.7 AAG07331.1 - 3.2e-33 115.3 0.1 3.8e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG07331.1 - 2.2e-10 40.8 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAG07331.1 - 0.0062 16.2 0.1 0.013 15.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAG07332.1 - 9.9e-30 104.0 0.0 1.2e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG07332.1 - 7.6e-06 26.2 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SBP_bac_3 PF00497.20 AAG07333.1 - 6.9e-59 199.0 0.0 1.4e-30 106.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Response_reg PF00072.24 AAG07333.1 - 8.4e-26 90.3 0.1 3.3e-25 88.4 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 AAG07333.1 - 1.3e-25 90.1 0.1 2.6e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG07333.1 - 4.8e-15 55.4 2.8 3.2e-14 52.7 0.2 3.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAG07333.1 - 3.8e-13 49.6 0.0 8.9e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAG07333.1 - 4.5e-13 49.2 0.0 1.3e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold Hpt PF01627.23 AAG07333.1 - 1.6e-09 37.9 0.7 1e-08 35.3 0.7 2.5 1 0 0 1 1 1 1 Hpt domain PAS_9 PF13426.7 AAG07333.1 - 2.3e-07 31.0 0.0 6.8e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain Lig_chan-Glu_bd PF10613.9 AAG07333.1 - 0.0077 16.4 0.0 0.035 14.3 0.0 2.1 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site PAS_10 PF13596.6 AAG07333.1 - 0.028 15.0 0.0 0.076 13.6 0.0 1.8 1 0 0 1 1 1 0 PAS domain FleQ PF06490.11 AAG07333.1 - 0.037 14.4 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Phosphonate-bd PF12974.7 AAG07333.1 - 0.09 12.4 3.2 6.2 6.3 0.5 3.9 2 2 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAG07333.1 - 0.096 12.6 0.0 0.52 10.2 0.0 2.1 3 0 0 3 3 3 0 NMT1/THI5 like HATPase_c_3 PF13589.6 AAG07333.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EAL PF00563.20 AAG07334.1 - 2.5e-63 213.8 0.0 3.3e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 EAL domain Response_reg PF00072.24 AAG07334.1 - 2.3e-11 43.9 0.0 4.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 AAG07335.1 - 9.1e-31 106.3 0.2 1.2e-30 105.9 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG07335.1 - 2.9e-18 65.2 0.0 5e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG07335.1 - 0.033 13.8 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG07335.1 - 0.088 12.3 0.0 0.36 10.4 0.0 2.1 2 1 0 2 2 2 0 Sigma-70, region 4 HI0933_like PF03486.14 AAG07336.1 - 8.7e-103 344.2 0.0 9.8e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 AAG07336.1 - 0.097 11.9 0.0 10 5.3 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DEAD PF00270.29 AAG07337.1 - 3.2e-48 163.8 0.0 7.7e-48 162.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG07337.1 - 9.2e-29 100.0 0.0 3.1e-28 98.3 0.0 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAG07337.1 - 1.2e-05 25.4 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAG07337.1 - 0.0067 16.8 0.1 0.43 10.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 AAG07337.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 AAG07337.1 - 0.53 10.6 2.5 3.7 7.8 1.0 2.9 2 1 0 2 2 2 0 AAA domain NYN PF01936.18 AAG07338.1 - 3e-35 121.9 0.0 3.5e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 NYN domain DUF2076 PF09849.9 AAG07339.1 - 4.5e-42 144.9 5.5 5.2e-42 144.7 5.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TauE PF01925.19 AAG07339.1 - 0.026 14.2 1.3 0.47 10.0 0.7 2.0 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DivIC PF04977.15 AAG07339.1 - 0.092 12.5 1.1 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 Septum formation initiator NPV_P10 PF05531.12 AAG07339.1 - 0.18 12.3 0.4 0.18 12.3 0.4 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YqfQ PF14181.6 AAG07339.1 - 0.35 11.0 2.2 0.47 10.6 2.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein Isochorismatase PF00857.20 AAG07340.1 - 5.1e-35 121.2 0.0 6.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Bac_luciferase PF00296.20 AAG07341.1 - 3.1e-78 263.4 1.2 3.8e-78 263.1 1.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase UPF0259 PF06790.11 AAG07342.1 - 7.9e-07 29.1 7.0 1.2e-06 28.5 4.5 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0259) GPDPase_memb PF10110.9 AAG07342.1 - 0.0015 17.4 3.6 0.0024 16.7 3.6 1.4 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Glyoxalase PF00903.25 AAG07343.1 - 1.4e-06 28.5 0.0 7.3e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF5570 PF17731.1 AAG07343.1 - 0.28 11.3 1.0 2.5 8.2 0.2 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5570) adh_short PF00106.25 AAG07344.1 - 5.1e-57 192.5 0.0 6.7e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG07344.1 - 5.3e-43 147.3 0.0 7.2e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG07344.1 - 7.7e-13 48.7 0.2 1.1e-12 48.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AAG07344.1 - 0.079 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 AAG07344.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Exo_endo_phos PF03372.23 AAG07345.1 - 5.8e-11 42.4 1.6 9.2e-11 41.7 1.6 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SBP_bac_3 PF00497.20 AAG07346.1 - 3.7e-06 26.5 0.0 9.1e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HrpB_C PF08482.10 AAG07348.1 - 1.9e-52 177.2 0.1 3.5e-52 176.3 0.1 1.5 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal Helicase_C PF00271.31 AAG07348.1 - 2e-14 53.9 0.0 3.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 AAG07348.1 - 1.4e-08 35.0 0.1 2.6e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 AAG07348.1 - 3.3e-07 30.2 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AAG07348.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 AAG07348.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 Flavivirus DEAD domain ResIII PF04851.15 AAG07348.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Cation_efflux PF01545.21 AAG07350.1 - 1.9e-37 128.9 11.5 2.4e-37 128.6 11.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAG07350.1 - 1.1e-22 79.9 0.0 1.6e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4271 PF14093.6 AAG07350.1 - 0.56 10.1 3.8 0.65 9.9 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) HTH_24 PF13412.6 AAG07352.1 - 1.4e-23 82.2 0.4 4e-23 80.7 0.2 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 AAG07352.1 - 1.5e-22 79.4 0.0 2.3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AAG07352.1 - 2.5e-19 68.8 1.2 4.8e-19 67.9 1.2 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAG07352.1 - 1.1e-08 34.8 0.2 1.9e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAG07352.1 - 1.5e-08 34.4 0.2 3.1e-08 33.5 0.2 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AAG07352.1 - 1.9e-08 34.1 0.1 3.2e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAG07352.1 - 7.6e-06 25.9 0.1 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 AAG07352.1 - 6.8e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 AAG07352.1 - 9.3e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 AAG07352.1 - 0.00016 21.6 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_1 PF00126.27 AAG07352.1 - 0.0028 17.6 0.0 0.0067 16.4 0.0 1.6 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_34 PF13601.6 AAG07352.1 - 0.0037 17.4 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_36 PF13730.6 AAG07352.1 - 0.0067 16.4 0.1 0.042 13.8 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 AAG07352.1 - 0.0095 15.9 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus Rrf2 PF02082.20 AAG07352.1 - 0.017 15.5 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Crp PF00325.20 AAG07352.1 - 0.019 14.6 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_5 PF01022.20 AAG07352.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_3 PF01381.22 AAG07352.1 - 0.069 13.2 0.0 0.74 9.9 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix TrmB PF01978.19 AAG07352.1 - 0.081 12.8 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 AAG07352.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain HxlR PF01638.17 AAG07352.1 - 0.14 12.0 0.0 0.95 9.4 0.0 2.1 1 1 1 2 2 2 0 HxlR-like helix-turn-helix BTRD1 PF17660.1 AAG07352.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 DUF2788 PF10981.8 AAG07353.1 - 3.2e-22 78.3 13.3 3.7e-22 78.1 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2788) EMP70 PF02990.16 AAG07353.1 - 0.11 11.2 2.1 0.11 11.2 2.1 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 Adeno_E3B PF03376.14 AAG07353.1 - 0.27 11.5 2.3 0.68 10.2 0.1 2.0 2 0 0 2 2 2 0 Adenovirus E3B protein FeoB_associated PF12669.7 AAG07353.1 - 1.6 9.2 4.3 0.5 10.8 0.3 1.9 1 1 1 2 2 2 0 FeoB-associated Cys-rich membrane protein Globin PF00042.22 AAG07354.1 - 0.0044 17.6 0.0 0.034 14.7 0.0 2.0 1 1 0 1 1 1 1 Globin PseudoU_synth_2 PF00849.22 AAG07355.1 - 2.7e-16 60.1 0.0 4.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase SPOR PF05036.13 AAG07355.1 - 0.099 13.0 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 Sporulation related domain Lactamase_B_2 PF12706.7 AAG07356.1 - 2.1e-42 144.9 1.0 3.1e-42 144.4 1.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAG07356.1 - 4.5e-16 59.2 0.0 6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAG07356.1 - 8.8e-06 25.9 2.4 0.05 13.6 1.3 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily NCE101 PF11654.8 AAG07356.1 - 0.19 11.5 0.3 0.51 10.1 0.3 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 AMNp_N PF10423.9 AAG07357.1 - 4.3e-51 172.6 0.3 5.9e-50 168.9 0.3 2.1 2 0 0 2 2 2 1 Bacterial AMP nucleoside phosphorylase N-terminus PNP_UDP_1 PF01048.20 AAG07357.1 - 1.3e-16 60.6 0.0 2.4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily 4HBT PF03061.22 AAG07358.1 - 4.1e-17 62.3 0.2 6.9e-17 61.6 0.2 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAG07358.1 - 5.6e-05 23.5 1.9 7.1e-05 23.2 1.9 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 AAG07358.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Acetyltransf_3 PF13302.7 AAG07358.1 - 0.063 14.0 0.0 0.067 13.9 0.0 1.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AidB_N PF18158.1 AAG07359.1 - 7.1e-61 204.7 1.3 1.4e-60 203.7 0.1 2.0 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAG07359.1 - 4.2e-29 101.7 1.5 1.5e-28 99.9 1.7 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG07359.1 - 1.8e-12 47.3 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG07359.1 - 5.5e-09 36.4 0.5 5.5e-09 36.4 0.5 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_N PF00440.23 AAG07360.1 - 7.6e-12 44.8 0.3 1.5e-11 43.9 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AAG07360.1 - 2.7e-05 24.4 0.1 7.7e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain 7TMR-DISM_7TM PF07695.11 AAG07361.1 - 2.5e-56 190.8 32.7 3.5e-56 190.3 32.7 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling 7TMR-DISMED2 PF07696.11 AAG07361.1 - 1.6e-36 125.3 0.2 3.7e-36 124.1 0.2 1.7 1 0 0 1 1 1 1 7TMR-DISM extracellular 2 Response_reg PF00072.24 AAG07361.1 - 2.7e-27 95.1 0.0 4.7e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAG07361.1 - 3.3e-23 82.3 0.0 5.7e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG07361.1 - 2.2e-14 53.2 0.1 2.2e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Ctr PF04145.15 AAG07361.1 - 0.65 10.6 5.5 41 4.8 3.8 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Phos_pyr_kin PF08543.12 AAG07362.1 - 7.1e-70 235.2 0.0 8.7e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF2563 PF10817.8 AAG07362.1 - 0.0069 17.0 0.1 6 7.5 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2563) PfkB PF00294.24 AAG07362.1 - 0.0094 15.3 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TMP-TENI PF02581.17 AAG07363.1 - 1.7e-53 180.6 0.1 2e-53 180.4 0.1 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase QRPTase_C PF01729.19 AAG07363.1 - 0.14 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Aminotran_3 PF00202.21 AAG07364.1 - 6.5e-77 258.9 0.0 8.5e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAG07364.1 - 5.5e-05 22.5 0.0 7.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Sel1 PF08238.12 AAG07365.1 - 1.3e-15 57.5 1.5 6.7e-09 36.1 0.3 2.4 2 0 0 2 2 2 2 Sel1 repeat TPR_16 PF13432.6 AAG07365.1 - 0.16 12.7 4.5 3.6 8.3 1.8 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat OmdA PF13376.6 AAG07365.1 - 0.19 11.8 0.2 5.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF1820 PF08850.11 AAG07366.1 - 1.4e-43 147.3 0.1 1.6e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1820) Radical_SAM PF04055.21 AAG07367.1 - 9.1e-29 101.0 0.0 1.5e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 AAG07367.1 - 4e-28 97.3 0.1 9.3e-28 96.2 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AAG07367.1 - 5.3e-20 71.2 0.0 1.1e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 TRAM domain B12-binding PF02310.19 AAG07367.1 - 0.0071 16.4 0.1 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain TRAM_2 PF18693.1 AAG07367.1 - 0.016 15.3 0.0 0.08 13.1 0.0 2.1 1 1 0 1 1 1 0 TRAM domain PhoH PF02562.16 AAG07368.1 - 5.9e-95 316.6 0.0 7.6e-95 316.2 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AAG07368.1 - 5.8e-09 36.0 0.0 1.2e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAG07368.1 - 2.9e-05 24.4 0.0 0.00011 22.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAG07368.1 - 0.0021 17.8 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 AAG07368.1 - 0.0044 17.3 0.3 0.14 12.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 AAG07368.1 - 0.03 14.1 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 AAG07368.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 AAG07368.1 - 0.13 11.8 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fumerase PF05681.14 AAG07368.1 - 0.15 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) UPF0054 PF02130.17 AAG07369.1 - 9.2e-36 122.5 0.0 1.1e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 CorC_HlyC PF03471.17 AAG07370.1 - 2.7e-21 75.4 0.1 1.2e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 AAG07370.1 - 8.9e-11 42.1 1.3 4.4e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 CBS domain CN_hydrolase PF00795.22 AAG07371.1 - 5.5e-29 101.3 0.0 8.3e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TruB_C PF09142.11 AAG07371.1 - 0.0037 17.0 0.1 0.021 14.6 0.0 2.3 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal DUF218 PF02698.17 AAG07372.1 - 1.1e-26 93.4 0.0 1.4e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain DUF4131 PF13567.6 AAG07372.1 - 4.7 6.8 10.0 2 8.1 7.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1451 PF07295.11 AAG07373.1 - 7.6e-05 22.8 2.2 0.05 13.6 0.2 2.2 2 0 0 2 2 2 2 Zinc-ribbon containing domain zf-RRN7 PF11781.8 AAG07373.1 - 0.003 17.2 0.6 0.053 13.2 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DNA_RNApol_7kD PF03604.13 AAG07373.1 - 0.075 12.7 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-NADH-PPase PF09297.11 AAG07373.1 - 0.14 11.8 3.9 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_recom PF13408.6 AAG07373.1 - 0.25 11.9 3.1 1.8 9.2 0.5 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain tRNA-synt_1_2 PF13603.6 AAG07374.1 - 3.3e-68 228.8 0.0 5.7e-68 228.1 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 AAG07374.1 - 2.1e-67 227.7 0.2 6e-46 156.9 1.7 5.7 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAG07374.1 - 1.1e-28 100.1 0.2 5.9e-19 68.1 0.0 4.5 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AAG07374.1 - 8.3e-15 55.1 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AAG07374.1 - 0.00068 19.1 0.0 0.73 9.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAG07374.1 - 0.0077 15.2 0.0 1.9 7.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) LptE PF04390.12 AAG07375.1 - 1e-09 39.0 2.0 1e-09 39.0 2.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide-assembly EF_TS PF00889.19 AAG07375.1 - 0.017 14.8 0.4 0.022 14.4 0.4 1.2 1 0 0 1 1 1 0 Elongation factor TS DUF3347 PF11827.8 AAG07375.1 - 0.19 11.9 2.9 0.24 11.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) LPAM_2 PF13627.6 AAG07375.1 - 2 8.4 3.9 3.1 7.8 3.9 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DNA_pol3_delta PF06144.13 AAG07376.1 - 1.2e-32 113.1 0.0 1.5e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delt_C PF14840.6 AAG07376.1 - 3.8e-14 53.1 0.0 8.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Processivity clamp loader gamma complex DNA pol III C-term DNA_pol3_gamma3 PF12169.8 AAG07376.1 - 0.023 14.6 0.1 0.071 13.0 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III ArfA PF03889.13 AAG07377.1 - 3.1e-11 42.6 2.5 3.6e-11 42.3 2.5 1.2 1 0 0 1 1 1 1 Alternative ribosome-rescue factor A SLT_2 PF13406.6 AAG07379.1 - 1.9e-110 368.7 0.0 2.4e-110 368.4 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain PG_binding_1 PF01471.18 AAG07379.1 - 6.7e-13 48.6 0.0 2.8e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 AAG07379.1 - 0.0078 16.5 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 Predicted Peptidoglycan domain Glucosaminidase PF01832.20 AAG07379.1 - 0.051 14.1 0.1 0.97 10.0 0.1 2.7 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Transposase_20 PF02371.16 AAG07380.1 - 7.2e-25 87.1 0.7 1.9e-24 85.8 0.7 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAG07380.1 - 5.4e-15 55.6 0.2 2.4e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 Transposase Cep57_MT_bd PF06657.13 AAG07380.1 - 0.0024 18.3 0.5 0.0056 17.1 0.1 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 HHH PF00633.23 AAG07380.1 - 0.02 14.7 0.1 0.063 13.2 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lzipper-MIP1 PF14389.6 AAG07380.1 - 0.021 15.1 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_transf_4 PF13439.6 AAG07380.1 - 0.054 13.5 0.4 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HalX PF08663.10 AAG07380.1 - 0.095 13.0 1.6 0.33 11.3 1.6 1.9 1 0 0 1 1 1 0 HalX domain DUF3287 PF11690.8 AAG07380.1 - 0.11 12.2 0.6 0.31 10.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ABC_tran_CTD PF16326.5 AAG07380.1 - 0.12 12.6 1.5 0.25 11.6 1.5 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AAG07380.1 - 0.4 10.8 3.0 0.23 11.5 0.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation Abhydrolase_1 PF00561.20 AAG07381.1 - 9e-15 55.0 0.3 1.5e-14 54.2 0.3 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG07381.1 - 2.3e-14 54.6 19.2 2.7e-14 54.3 19.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG07381.1 - 1.9e-09 37.2 0.0 0.00017 21.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 AAG07381.1 - 0.092 12.3 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family LysR_substrate PF03466.20 AAG07382.1 - 4.8e-31 107.7 6.2 4.8e-31 107.7 6.2 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07382.1 - 4.9e-18 64.8 1.1 1.2e-17 63.6 1.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAG07382.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Radical_SAM PF04055.21 AAG07383.1 - 8.8e-15 55.5 0.0 1.4e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 AAG07383.1 - 4e-08 33.6 0.2 2.1e-07 31.3 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family BPL_LplA_LipB PF03099.19 AAG07384.1 - 1.3e-05 25.1 0.0 3.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF493 PF04359.14 AAG07385.1 - 2.1e-28 98.7 0.0 2.3e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF493) Peptidase_S11 PF00768.20 AAG07386.1 - 8.2e-88 293.9 0.0 1.1e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 AAG07386.1 - 1.1e-24 86.5 0.1 1.8e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 AAG07386.1 - 1.7e-14 53.9 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 AAG07386.1 - 0.0002 20.2 0.0 0.00039 19.3 0.0 1.4 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase PF00144.24 AAG07386.1 - 0.0016 17.8 0.1 0.077 12.2 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase DPBB_1 PF03330.18 AAG07387.1 - 2.1e-26 92.0 0.0 4.1e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase SPOR PF05036.13 AAG07387.1 - 2.4e-11 43.8 1.3 5.9e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 Sporulation related domain DUF3275 PF11679.8 AAG07387.1 - 0.16 12.0 1.1 0.25 11.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) SLT_2 PF13406.6 AAG07388.1 - 1.4e-101 339.6 0.0 1.7e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT PF01464.20 AAG07388.1 - 0.0016 18.1 0.0 0.0063 16.2 0.0 1.8 1 1 0 1 1 1 1 Transglycosylase SLT domain FTSW_RODA_SPOVE PF01098.19 AAG07389.1 - 3e-113 378.5 26.5 3.5e-113 378.3 26.5 1.0 1 0 0 1 1 1 1 Cell cycle protein Transpeptidase PF00905.22 AAG07390.1 - 1.9e-75 253.9 0.0 3.7e-75 253.0 0.0 1.4 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AAG07390.1 - 1.1e-46 159.5 0.0 2.1e-46 158.6 0.0 1.5 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain SPOUT_MTase PF02590.17 AAG07391.1 - 3.8e-47 160.1 0.0 4.2e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase RsfS PF02410.15 AAG07392.1 - 1.3e-28 99.3 0.0 1.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CTP_transf_like PF01467.26 AAG07393.1 - 6.2e-31 107.5 0.0 7.4e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Aldedh PF00171.22 AAG07394.1 - 2.9e-21 75.5 6.5 4e-14 52.0 3.3 2.4 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF2564 PF10819.8 AAG07394.1 - 3 8.3 6.1 7.5 7.0 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Abhydrolase_1 PF00561.20 AAG07395.1 - 3e-14 53.3 0.1 1.3e-12 47.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAG07395.1 - 6.5e-07 28.9 0.1 0.00038 19.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 AAG07395.1 - 0.00028 19.7 0.0 0.00043 19.1 0.0 1.4 1 1 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 AAG07395.1 - 0.02 15.0 0.0 0.073 13.2 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein FSH1 PF03959.13 AAG07395.1 - 0.2 11.3 0.1 0.85 9.2 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LCM PF04072.14 AAG07396.1 - 5.3e-16 59.1 0.0 8.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Pur_DNA_glyco PF02245.16 AAG07397.1 - 7.4e-36 123.2 0.0 9.1e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) PAP2 PF01569.21 AAG07398.1 - 5.4e-21 74.8 6.7 5.4e-21 74.8 6.7 4.3 3 2 1 4 4 4 1 PAP2 superfamily SNARE_assoc PF09335.11 AAG07398.1 - 1.3e-18 67.6 6.8 1.3e-18 67.6 6.8 3.6 3 2 1 4 4 4 1 SNARE associated Golgi protein PAP2_3 PF14378.6 AAG07398.1 - 1e-07 31.8 5.6 1e-07 31.8 5.6 3.1 3 0 0 3 3 3 2 PAP2 superfamily L6_membrane PF05805.12 AAG07398.1 - 0.027 14.0 0.6 0.083 12.4 0.6 1.8 1 0 0 1 1 1 0 L6 membrane protein PAP2_C PF14360.6 AAG07398.1 - 6.7 7.3 6.6 0.82 10.2 0.1 2.7 3 0 0 3 3 3 0 PAP2 superfamily C-terminal LON_substr_bdg PF02190.16 AAG07399.1 - 1.2e-21 77.5 0.0 9.3e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain LrgB PF04172.16 AAG07400.1 - 3.8e-72 242.3 21.6 4.4e-72 242.1 21.6 1.0 1 0 0 1 1 1 1 LrgB-like family HlyIII PF03006.20 AAG07400.1 - 1.3 8.7 7.0 0.79 9.4 4.4 1.9 1 1 1 2 2 2 0 Haemolysin-III related Wzy_C PF04932.15 AAG07400.1 - 8.1 6.1 17.9 0.15 11.7 0.4 3.7 1 1 2 3 3 3 0 O-Antigen ligase LrgA PF03788.14 AAG07401.1 - 1.7e-20 72.8 7.4 2.3e-20 72.4 7.4 1.2 1 0 0 1 1 1 1 LrgA family RseC_MucC PF04246.12 AAG07401.1 - 6.3 6.8 8.1 0.41 10.6 2.2 1.8 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4229 PF14012.6 AAG07401.1 - 6.4 7.0 10.3 0.1 12.7 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) MaoC_dehydratas PF01575.19 AAG07402.1 - 7.1e-26 90.2 0.0 8.8e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAG07402.1 - 1.6e-05 25.1 0.0 2.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Peptidase_C13 PF01650.18 AAG07403.1 - 1.7e-45 155.5 0.0 1.3e-43 149.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase C13 family MORN PF02493.20 AAG07403.1 - 5.3e-35 117.2 62.0 7.2e-06 25.6 0.5 11.7 12 0 0 12 12 12 10 MORN repeat Peptidase_C14 PF00656.22 AAG07403.1 - 9.4e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HIM1 PF08732.10 AAG07404.1 - 2.8e-07 30.2 0.0 3.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 AAG07404.1 - 0.00017 21.2 0.0 0.071 12.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAG07404.1 - 0.0038 17.1 0.0 0.0065 16.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 AAG07404.1 - 0.0078 16.6 0.0 0.024 15.1 0.0 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 AAG07404.1 - 0.014 14.6 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein DUF1471 PF07338.13 AAG07404.1 - 0.16 11.9 0.0 0.45 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) DUF1375 PF07119.12 AAG07405.1 - 3e-16 59.5 0.1 4.6e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1375) Flavoprotein PF02441.19 AAG07406.1 - 9.3e-25 87.2 0.0 1.2e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Mur_ligase_M PF08245.12 AAG07407.1 - 6.4e-22 78.5 0.0 9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AAG07407.1 - 1.9e-19 69.7 0.0 6.5e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AAG07407.1 - 3.6e-09 36.8 0.1 1.2e-08 35.1 0.1 1.9 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Sigma54_activat PF00158.26 AAG07408.1 - 3.7e-59 199.2 0.0 6.4e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG07408.1 - 1.2e-19 70.7 0.0 3.2e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG07408.1 - 5.1e-14 51.8 2.0 6.9e-14 51.4 0.3 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family GAF PF01590.26 AAG07408.1 - 5.5e-08 33.5 0.4 2.7e-07 31.3 0.1 2.2 2 0 0 2 2 2 1 GAF domain PAS_4 PF08448.10 AAG07408.1 - 1e-07 32.2 0.7 0.00067 19.9 0.0 3.6 3 0 0 3 3 3 2 PAS fold HTH_23 PF13384.6 AAG07408.1 - 7.3e-06 25.6 0.4 7.3e-06 25.6 0.4 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 AAG07408.1 - 7.7e-05 23.2 2.6 0.00048 20.7 0.1 3.0 1 1 1 2 2 2 1 Homeodomain-like domain PAS_9 PF13426.7 AAG07408.1 - 0.00012 22.3 0.0 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 AAG07408.1 - 0.00013 21.9 0.1 0.00074 19.5 0.0 2.3 2 0 0 2 2 1 1 PAS domain AAA_5 PF07728.14 AAG07408.1 - 0.0002 21.3 0.0 0.00059 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IclR PF01614.18 AAG07408.1 - 0.00043 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_28 PF13518.6 AAG07408.1 - 0.00049 20.2 0.5 0.0067 16.5 0.7 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_22 PF13309.6 AAG07408.1 - 0.00052 20.0 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_7 PF02796.15 AAG07408.1 - 0.00076 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_20 PF12840.7 AAG07408.1 - 0.00076 19.5 0.5 0.0068 16.4 0.5 2.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AAG07408.1 - 0.00094 18.9 0.2 0.004 16.9 0.2 2.2 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_AraC PF00165.23 AAG07408.1 - 0.001 19.1 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_17 PF12728.7 AAG07408.1 - 0.0017 18.5 0.1 0.0072 16.5 0.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain PAS_7 PF12860.7 AAG07408.1 - 0.0021 18.2 0.0 0.0081 16.3 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAG07408.1 - 0.0034 17.4 0.0 0.1 12.6 0.0 3.0 3 0 0 3 3 3 1 PAS fold HTH_50 PF18024.1 AAG07408.1 - 0.0051 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DprA_WH PF17782.1 AAG07408.1 - 0.0066 16.5 0.5 0.037 14.2 0.5 2.4 1 0 0 1 1 1 1 DprA winged helix domain Mg_chelatase PF01078.21 AAG07408.1 - 0.0074 15.7 0.2 0.22 10.9 0.2 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI HTH_10 PF04967.12 AAG07408.1 - 0.031 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain AAA PF00004.29 AAG07408.1 - 0.034 14.6 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_29 PF13551.6 AAG07408.1 - 0.039 14.0 0.4 0.14 12.2 0.4 2.0 1 0 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.6 AAG07408.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 AAG07408.1 - 0.049 14.2 0.2 0.27 11.8 0.2 2.3 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_IclR PF09339.10 AAG07408.1 - 0.07 12.9 2.7 0.18 11.6 0.2 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAG07408.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Aldedh PF00171.22 AAG07409.1 - 1.9e-163 544.3 0.0 2.1e-163 544.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.6 AAG07410.1 - 5.6e-40 137.5 43.9 6.7e-40 137.2 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAG07410.1 - 9e-27 93.8 39.1 1.2e-26 93.4 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease EutB PF06751.11 AAG07411.1 - 1.5e-220 732.5 0.0 1.9e-220 732.2 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) EutC PF05985.11 AAG07412.1 - 1.3e-94 315.9 0.0 1.5e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) Acetyltransf_1 PF00583.25 AAG07413.1 - 1.1e-13 51.4 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG07413.1 - 3.4e-10 40.0 0.1 4.8e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG07413.1 - 2e-08 34.5 0.1 2.5e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG07413.1 - 3.9e-08 33.6 0.0 5.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAG07413.1 - 4.9e-06 26.3 0.1 7.1e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 AAG07413.1 - 6.4e-05 23.6 0.0 7.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG07413.1 - 0.00031 20.5 0.2 0.0013 18.4 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG07413.1 - 0.0013 18.6 0.1 0.0042 17.0 0.1 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_18 PF18014.1 AAG07413.1 - 0.01 15.7 0.1 0.86 9.4 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG07413.1 - 0.03 14.5 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 AAG07413.1 - 0.065 13.2 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase SBP_bac_3 PF00497.20 AAG07414.1 - 3.9e-17 62.4 0.0 5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 RsmJ PF04378.13 AAG07414.1 - 0.062 12.5 0.1 0.091 12.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ SNARE_assoc PF09335.11 AAG07416.1 - 2.6e-25 89.3 2.4 2.6e-25 89.3 2.4 1.8 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4083 PF13314.6 AAG07416.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Peptidase_M90 PF06167.12 AAG07417.1 - 4.4e-88 295.0 0.0 5.1e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 Pyrophosphatase PF00719.19 AAG07418.1 - 2e-54 183.7 0.0 2.3e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Response_reg PF00072.24 AAG07419.1 - 6.1e-23 81.1 0.0 8.1e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG07419.1 - 3.8e-19 68.5 0.1 8e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal VirK PF06903.12 AAG07419.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 VirK protein MIP PF00230.20 AAG07421.1 - 4.4e-46 157.4 15.9 5e-46 157.2 15.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3522 PF12036.8 AAG07421.1 - 0.26 11.5 1.2 0.42 10.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) FecR PF04773.13 AAG07422.1 - 5.7e-16 58.9 0.1 1.8e-15 57.4 0.1 1.8 2 0 0 2 2 2 1 FecR protein CHASE2 PF05226.11 AAG07423.1 - 1.1e-54 185.9 0.1 2.1e-54 184.9 0.1 1.4 1 0 0 1 1 1 1 CHASE2 domain HATPase_c PF02518.26 AAG07423.1 - 1.2e-20 74.1 0.0 2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAG07423.1 - 1.5e-06 28.4 0.9 2.8e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AAG07423.1 - 0.00013 21.9 0.6 0.00044 20.2 0.6 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAG07423.1 - 0.00015 21.7 0.0 0.00061 19.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAG07423.1 - 0.0015 18.6 0.0 0.0063 16.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAG07423.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 PAS domain HATPase_c_2 PF13581.6 AAG07423.1 - 0.047 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAG07423.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tweety PF04906.13 AAG07423.1 - 0.22 10.1 0.9 0.37 9.4 0.9 1.2 1 0 0 1 1 1 0 Tweety HATPase_c_5 PF14501.6 AAG07423.1 - 0.26 11.2 0.0 0.46 10.4 0.0 1.3 1 0 0 1 1 1 0 GHKL domain DUF4407 PF14362.6 AAG07423.1 - 3.4 6.9 7.0 8.3 5.7 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran PF00005.27 AAG07424.1 - 3.4e-31 108.6 0.0 5.1e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07424.1 - 8.5e-13 48.8 1.6 1.7e-07 31.4 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAG07424.1 - 5.3e-05 23.1 0.1 0.099 12.3 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AAG07424.1 - 0.0039 16.7 0.8 0.43 10.0 0.8 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG07424.1 - 0.0072 16.0 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG07424.1 - 0.0096 16.3 0.1 0.018 15.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2813 PF11398.8 AAG07424.1 - 0.017 14.4 0.0 4.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) MeaB PF03308.16 AAG07424.1 - 0.03 13.3 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 AAG07424.1 - 0.036 14.0 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Erythro_esteras PF05139.14 AAG07424.1 - 0.043 13.6 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Erythromycin esterase AAA_7 PF12775.7 AAG07424.1 - 0.049 13.2 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 AAG07424.1 - 0.05 13.3 0.0 0.091 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAG07424.1 - 0.058 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAG07424.1 - 0.062 13.0 0.1 11 5.7 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 AAG07424.1 - 0.068 13.7 0.5 0.13 12.7 0.2 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAG07424.1 - 0.082 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 AAG07424.1 - 0.089 13.1 0.3 0.39 11.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAG07424.1 - 0.12 12.9 0.2 0.81 10.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAG07424.1 - 0.15 11.9 0.2 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 AAG07424.1 - 0.17 11.4 0.3 1.7 8.2 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAG07424.1 - 0.18 11.5 0.1 0.39 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 AAG07425.1 - 6.5e-10 38.6 11.8 6.5e-10 38.6 11.8 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AAG07425.1 - 5.3e-09 35.8 12.8 2.2e-08 33.7 12.7 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AAG07425.1 - 4.5e-08 32.9 5.7 1.4e-07 31.2 5.7 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAG07425.1 - 6e-08 32.9 5.8 1.3e-07 31.7 5.8 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein CcmB PF03379.13 AAG07425.1 - 1.5e-07 31.2 4.4 1.5e-07 31.2 4.4 2.2 1 1 1 2 2 2 1 CcmB protein ABC_transp_aux PF09822.9 AAG07426.1 - 1e-61 208.8 0.0 1.4e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system FapA PF03961.13 AAG07426.1 - 0.0082 14.8 0.1 0.011 14.3 0.1 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF4340 PF14238.6 AAG07427.1 - 9.5e-13 48.6 0.0 1.3e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4340) MR_MLE_C PF13378.6 AAG07428.1 - 1.2e-32 113.3 0.1 1.7e-32 112.8 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 AAG07428.1 - 1.1e-05 25.7 0.4 3.5e-05 24.0 0.4 1.8 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Methyltransf_14 PF08484.11 AAG07428.1 - 0.069 13.0 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Exonuc_VII_S PF02609.16 AAG07429.1 - 4.4e-20 71.5 3.7 5.8e-20 71.1 3.7 1.2 1 0 0 1 1 1 1 Exonuclease VII small subunit SHOCT PF09851.9 AAG07429.1 - 0.023 14.4 1.4 0.16 11.8 1.0 2.5 2 0 0 2 2 2 0 Short C-terminal domain polyprenyl_synt PF00348.17 AAG07430.1 - 1.5e-58 197.9 0.1 1.9e-58 197.6 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Phage_CP76 PF06892.11 AAG07430.1 - 0.043 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) DXP_synthase_N PF13292.6 AAG07431.1 - 3.1e-121 403.7 0.0 1.2e-120 401.8 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AAG07431.1 - 1.8e-37 128.8 0.0 4.3e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAG07431.1 - 1.7e-27 95.8 0.1 4.1e-27 94.5 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 AAG07431.1 - 4.5e-07 29.8 0.7 3.6e-06 26.8 0.1 2.8 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AAG07431.1 - 1.1e-06 27.9 0.1 1.7e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 AAG07431.1 - 0.0014 17.7 0.0 0.11 11.5 0.1 2.7 3 0 0 3 3 3 1 Transketolase, thiamine diphosphate binding domain Peripla_BP_2 PF01497.18 AAG07432.1 - 1.7e-24 86.7 0.0 2.1e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Erythro-docking PF09277.11 AAG07432.1 - 0.11 12.4 2.2 0.29 11.0 2.2 1.7 1 0 0 1 1 1 0 Erythronolide synthase, docking GTP_cyclohydro2 PF00925.20 AAG07434.1 - 1.4e-67 226.4 0.0 1.7e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II gag-asp_proteas PF13975.6 AAG07435.1 - 5.9e-27 94.1 0.2 1.1e-26 93.2 0.0 1.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AAG07435.1 - 1.1e-20 74.0 0.7 1.5e-20 73.6 0.1 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 AAG07435.1 - 0.00034 20.4 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 AAG07435.1 - 0.066 13.5 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease T2SSB PF16537.5 AAG07435.1 - 0.14 11.8 0.1 0.71 9.5 0.1 2.2 1 1 1 2 2 2 0 Type II secretion system protein B SBP_bac_3 PF00497.20 AAG07436.1 - 9.7e-11 41.5 0.0 1.7e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PgpA PF04608.13 AAG07437.1 - 1.9e-52 177.1 9.6 2.1e-52 176.9 9.6 1.0 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A AIRS PF00586.24 AAG07438.1 - 3.4e-24 85.3 0.8 3.4e-24 85.3 0.8 1.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AAG07438.1 - 2.7e-06 27.6 0.2 4.9e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain NusB PF01029.18 AAG07439.1 - 6e-34 117.2 0.0 7e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 NusB family DMRL_synthase PF00885.19 AAG07440.1 - 1.7e-56 189.9 0.4 1.9e-56 189.8 0.4 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DHBP_synthase PF00926.19 AAG07441.1 - 8e-85 283.2 1.1 1e-84 282.8 1.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 AAG07441.1 - 3.3e-30 104.8 0.0 7.2e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II Lum_binding PF00677.17 AAG07442.1 - 3.1e-47 158.5 0.1 2.7e-24 85.0 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain RibD_C PF01872.17 AAG07443.1 - 3.7e-47 160.7 0.0 5e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AAG07443.1 - 8.8e-20 70.5 0.0 1.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAG07443.1 - 6.2e-12 45.5 0.0 8.9e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase ATP-cone PF03477.16 AAG07444.1 - 8.4e-14 51.9 0.1 1.2e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 ATP cone domain Lar_restr_allev PF14354.6 AAG07444.1 - 0.0017 18.7 0.1 0.0027 18.0 0.1 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar BAG PF02179.16 AAG07444.1 - 0.0055 17.1 0.1 0.015 15.7 0.1 1.7 1 0 0 1 1 1 1 BAG domain Myc-LZ PF02344.15 AAG07444.1 - 0.048 13.8 0.8 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 Myc leucine zipper domain Zn-ribbon_8 PF09723.10 AAG07444.1 - 0.059 13.5 1.1 8.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Nre_C PF04895.12 AAG07444.1 - 0.063 13.2 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Archaeal Nre, C-terminal Zn_Tnp_IS1595 PF12760.7 AAG07444.1 - 0.082 12.9 0.9 0.14 12.1 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Cys_rich_CPXG PF14255.6 AAG07444.1 - 0.41 10.6 1.3 2.5 8.1 1.4 2.1 1 1 1 2 2 2 0 Cysteine-rich CPXCG YscW PF09619.10 AAG07445.1 - 1.5e-05 25.3 0.0 5.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Type III secretion system lipoprotein chaperone (YscW) LPAM_1 PF08139.12 AAG07445.1 - 1.4 9.6 5.9 2.8 8.6 5.9 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site PrmA PF06325.13 AAG07446.1 - 0.00023 20.7 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 AAG07446.1 - 0.003 17.3 0.4 0.0043 16.8 0.4 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 AAG07446.1 - 0.03 13.9 0.0 0.074 12.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 AAG07447.1 - 0.0016 18.2 0.1 0.002 17.9 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase ABC_transp_aux PF09822.9 AAG07447.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Thioredoxin PF00085.20 AAG07448.1 - 3.2e-27 94.5 0.0 5e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TPR_20 PF14561.6 AAG07448.1 - 3.4e-27 94.6 18.7 4.7e-27 94.1 4.7 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AAG07448.1 - 5e-12 46.2 24.3 3.8e-11 43.3 9.4 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat Thioredoxin_2 PF13098.6 AAG07448.1 - 5.5e-09 36.4 0.1 6.5e-08 33.0 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain ANAPC3 PF12895.7 AAG07448.1 - 1.1e-08 35.2 4.1 1.5e-05 25.1 0.2 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Thioredoxin_8 PF13905.6 AAG07448.1 - 4.9e-07 30.0 0.0 3.2e-06 27.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like TPR_16 PF13432.6 AAG07448.1 - 3.5e-05 24.4 7.3 3.5e-05 24.4 7.3 3.0 1 1 1 2 2 1 1 Tetratricopeptide repeat AhpC-TSA PF00578.21 AAG07448.1 - 0.00056 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 AAG07448.1 - 0.00094 18.6 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TPR_14 PF13428.6 AAG07448.1 - 0.00099 19.7 1.8 0.00099 19.7 1.8 4.6 2 1 3 5 5 4 1 Tetratricopeptide repeat Thioredoxin_7 PF13899.6 AAG07448.1 - 0.0012 19.0 0.1 0.0032 17.6 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 AAG07448.1 - 0.0055 16.7 0.0 0.0094 16.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain TPR_4 PF07721.14 AAG07448.1 - 0.015 15.9 4.7 0.015 15.9 4.7 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAG07448.1 - 0.026 14.9 7.3 0.086 13.3 1.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AAG07448.1 - 0.1 13.1 2.9 6 7.3 0.1 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Thioredoxin_6 PF13848.6 AAG07448.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.11 AAG07448.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 AAG07448.1 - 0.12 12.2 0.1 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.10 AAG07448.1 - 0.12 12.0 0.0 0.46 10.2 0.0 1.8 1 1 0 1 1 1 0 Redoxin TPR_2 PF07719.17 AAG07448.1 - 3.5 8.0 13.3 8 6.9 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2796 PF10986.8 AAG07450.1 - 1.6e-55 187.6 7.6 1.6e-55 187.6 7.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2796) Zip PF02535.22 AAG07450.1 - 6.7 5.8 9.6 11 5.1 9.6 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter ABC_tran PF00005.27 AAG07451.1 - 2.2e-27 96.2 0.0 2.7e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07451.1 - 6.9e-08 32.6 1.2 0.0013 18.6 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AAG07451.1 - 0.001 18.8 0.1 0.35 10.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AAG07451.1 - 0.0046 16.7 0.1 0.0091 15.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG07451.1 - 0.0067 16.7 1.2 0.48 10.7 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAG07451.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAG07451.1 - 0.024 15.0 6.9 0.15 12.4 6.8 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AAG07451.1 - 0.027 14.0 0.2 0.96 9.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAG07451.1 - 0.12 12.1 0.1 2.7 7.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein DLIC PF05783.11 AAG07451.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 AAG07451.1 - 0.27 11.2 0.7 0.54 10.3 0.7 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsX PF02687.21 AAG07452.1 - 1.4e-13 51.1 1.6 1.4e-13 51.1 1.6 3.1 3 0 0 3 3 3 1 FtsX-like permease family MacB_PCD PF12704.7 AAG07452.1 - 9e-13 49.0 0.1 9e-13 49.0 0.1 1.6 2 0 0 2 2 2 1 MacB-like periplasmic core domain DUF3487 PF11990.8 AAG07452.1 - 0.068 13.0 5.7 2.3 8.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF3299 PF11736.8 AAG07453.1 - 1.5e-46 157.9 0.1 1.7e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3299) OmpW PF03922.14 AAG07454.1 - 1.1e-76 257.0 0.1 1.3e-76 256.8 0.1 1.0 1 0 0 1 1 1 1 OmpW family OMP_b-brl PF13505.6 AAG07454.1 - 6.2e-13 49.3 4.2 7.5e-13 49.0 4.2 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Porin_5 PF16930.5 AAG07454.1 - 0.072 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative porin Neurokinin_B PF03823.14 AAG07454.1 - 0.29 11.2 0.6 28 4.9 0.0 2.2 2 0 0 2 2 2 0 Neurokinin B Epimerase PF01370.21 AAG07455.1 - 3.5e-66 223.1 0.0 4.2e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAG07455.1 - 4.2e-54 184.2 0.0 4.7e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAG07455.1 - 4.1e-21 75.2 0.0 6.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAG07455.1 - 1.3e-19 70.8 0.2 3.6e-19 69.4 0.2 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AAG07455.1 - 2.6e-14 53.1 0.0 2.5e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AAG07455.1 - 3.7e-14 52.5 0.0 5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAG07455.1 - 2.8e-11 43.1 0.2 2.5e-07 30.2 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 AAG07455.1 - 4.4e-10 39.5 0.3 8.5e-10 38.6 0.3 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 AAG07455.1 - 0.00012 22.0 3.2 0.00034 20.6 2.4 2.1 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 AAG07455.1 - 0.00083 18.9 0.4 0.0026 17.3 0.3 1.9 2 1 0 2 2 2 1 short chain dehydrogenase Glyco_transf_4 PF13439.6 AAG07455.1 - 0.034 14.2 0.3 6.2 6.8 0.1 2.6 3 0 0 3 3 3 0 Glycosyltransferase Family 4 TrkA_N PF02254.18 AAG07455.1 - 0.062 13.6 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 AAG07456.1 - 2e-79 266.7 0.0 2.3e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAG07456.1 - 0.00044 19.8 0.0 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HTH_18 PF12833.7 AAG07457.1 - 6.6e-21 74.4 0.3 1.4e-20 73.4 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07457.1 - 5.4e-13 48.7 0.1 4.6e-10 39.3 0.1 2.8 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 AAG07457.1 - 3.4e-10 39.9 6.0 3.4e-10 39.9 6.0 1.7 1 1 1 2 2 2 1 AraC-binding-like domain HTH_32 PF13565.6 AAG07457.1 - 0.059 14.0 0.3 0.2 12.3 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain SpoU_methylas_C PF12105.8 AAG07457.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.9 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal DUF3156 PF11354.8 AAG07458.1 - 4.3e-56 189.3 0.5 5e-56 189.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3156) AA_permease_2 PF13520.6 AAG07459.1 - 6.5e-32 110.9 30.3 8.2e-32 110.6 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAG07459.1 - 4.5e-11 42.0 28.0 1.5e-10 40.3 28.0 1.7 1 1 0 1 1 1 1 Amino acid permease CCG PF02754.16 AAG07459.1 - 0.096 12.9 0.1 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Cysteine-rich domain Aldedh PF00171.22 AAG07460.1 - 1.4e-174 581.0 0.0 1.6e-174 580.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GerE PF00196.19 AAG07461.1 - 5.8e-11 41.8 0.0 9.6e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Autoind_bind PF03472.15 AAG07461.1 - 0.0011 18.5 0.7 0.0016 18.0 0.7 1.2 1 0 0 1 1 1 1 Autoinducer binding domain Sigma70_r4_2 PF08281.12 AAG07461.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 AAG07461.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Methyltransf_11 PF08241.12 AAG07462.1 - 0.00046 20.8 0.0 0.0037 17.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG07462.1 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG07462.1 - 0.0084 16.8 0.0 0.032 14.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain TMEM190 PF15431.6 AAG07463.1 - 0.063 13.4 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 190 DUF4579 PF15158.6 AAG07463.1 - 0.11 12.2 0.3 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) EptA_B_N PF08019.12 AAG07463.1 - 0.28 11.1 3.8 0.16 11.8 0.8 1.8 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB HTH_3 PF01381.22 AAG07464.1 - 1.9e-16 59.8 0.0 2.1e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAG07464.1 - 3.2e-14 53.0 0.4 4e-14 52.7 0.4 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG07464.1 - 2.7e-13 49.7 0.0 3e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AAG07464.1 - 2.4e-06 27.3 0.1 3.5e-06 26.8 0.1 1.2 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAG07464.1 - 1.8e-05 25.1 0.0 2.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.16 AAG07464.1 - 0.0002 20.8 0.1 0.00042 19.8 0.1 1.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 AAG07464.1 - 0.00023 21.0 0.1 0.00036 20.4 0.1 1.3 1 0 0 1 1 1 1 HTH domain Sigma70_r4_2 PF08281.12 AAG07464.1 - 0.00089 18.9 0.0 0.0047 16.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG07464.1 - 0.0012 18.6 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 AAG07464.1 - 0.003 17.1 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AAG07464.1 - 0.0034 17.1 0.1 0.0057 16.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAG07464.1 - 0.0078 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAG07464.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_32 PF13565.6 AAG07464.1 - 0.035 14.7 0.1 0.048 14.3 0.1 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 AAG07464.1 - 0.079 13.1 0.3 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AAG07464.1 - 0.16 11.8 0.8 0.6 10.0 0.3 2.2 2 1 1 3 3 3 0 AsnC-type helix-turn-helix domain AMP-binding PF00501.28 AAG07465.1 - 1.6e-80 270.8 0.0 2.2e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 AAG07465.1 - 3.5e-50 170.6 0.0 4.9e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.6 AAG07465.1 - 1e-12 48.9 0.0 4e-12 47.0 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AAG07465.1 - 5.8e-10 39.4 0.0 1.6e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 AAG07465.1 - 2.6e-08 33.6 0.0 6.3e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG07465.1 - 0.029 13.5 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3662 PF12401.8 AAG07465.1 - 0.041 14.2 0.1 6.8 7.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) adh_short PF00106.25 AAG07466.1 - 2.6e-27 95.6 0.0 3.3e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG07466.1 - 7.1e-22 78.1 0.0 8.5e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG07466.1 - 5.4e-05 23.2 0.2 7.9e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG07466.1 - 5.9e-05 22.6 0.0 0.00013 21.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG07466.1 - 0.0019 17.4 0.1 0.0037 16.4 0.1 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AAG07466.1 - 0.022 14.3 0.1 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Response_reg PF00072.24 AAG07467.1 - 1.3e-16 60.7 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG07467.1 - 2.2e-13 49.5 0.1 3.6e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AAG07467.1 - 1.2e-06 27.9 0.3 2.9e-06 26.7 0.3 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAG07467.1 - 2.4e-05 23.9 0.1 4.9e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 TetR_C_28 PF17937.1 AAG07467.1 - 0.00092 19.6 0.0 0.03 14.8 0.0 2.4 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_38 PF13936.6 AAG07467.1 - 0.011 15.4 0.2 0.027 14.2 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAG07467.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_40 PF14493.6 AAG07467.1 - 0.02 15.4 0.1 0.072 13.5 0.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 AAG07467.1 - 0.023 14.8 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase LysR_substrate PF03466.20 AAG07467.1 - 0.031 13.7 0.1 8.6 5.7 0.0 2.5 2 1 0 2 2 2 0 LysR substrate binding domain HTH_24 PF13412.6 AAG07467.1 - 0.094 12.3 0.1 0.29 10.7 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fimbrial PF00419.20 AAG07468.1 - 9.8e-07 29.2 0.0 3.2e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Fimbrial protein Glug PF07581.12 AAG07469.1 - 3.6e-34 114.9 113.0 5.9e-05 23.2 0.6 15.7 15 0 0 15 15 15 13 The GLUG motif Haemagg_act PF05860.13 AAG07469.1 - 5.7e-27 94.0 1.7 5.7e-27 94.0 1.7 2.7 2 0 0 2 2 2 1 haemagglutination activity domain ESPR PF13018.6 AAG07469.1 - 1.3e-08 34.5 2.1 1.3e-08 34.5 0.4 1.9 2 0 0 2 2 2 1 Extended Signal Peptide of Type V secretion system Peptidase_M26_N PF05342.14 AAG07469.1 - 0.034 13.6 0.3 0.055 12.9 0.3 1.3 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region PapD_N PF00345.20 AAG07470.1 - 5.7e-35 119.9 0.0 8.5e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAG07470.1 - 2.4e-09 37.4 0.0 4.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain Usher PF00577.20 AAG07471.1 - 1.4e-155 519.3 6.6 1.7e-155 519.1 6.6 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AAG07471.1 - 9e-37 126.3 0.0 1.7e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AAG07471.1 - 2e-19 69.2 0.6 1.5e-18 66.4 0.1 2.5 2 0 0 2 2 2 1 PapC C-terminal domain Big_6 PF17936.1 AAG07471.1 - 0.022 15.0 0.0 0.071 13.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig domain PapD_N PF00345.20 AAG07472.1 - 3.2e-41 140.1 0.0 5e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAG07472.1 - 8.5e-23 80.5 0.4 1.1e-21 76.9 0.5 2.3 2 0 0 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain FimA PF16970.5 AAG07473.1 - 2.4e-06 27.8 2.4 6.4e-06 26.4 1.1 2.0 2 0 0 2 2 2 1 Type-1 fimbrial protein, A MoaF_C PF17409.2 AAG07474.1 - 1.2e-52 176.4 0.0 1.4e-49 166.4 0.0 2.1 2 0 0 2 2 2 2 MoaF C-terminal domain MoaF PF10703.9 AAG07474.1 - 3.8e-36 123.3 0.0 2.6e-34 117.4 0.0 2.2 2 0 0 2 2 2 2 MoaF N-terminal domain Aminotran_3 PF00202.21 AAG07475.1 - 2.3e-41 141.8 0.0 3.8e-41 141.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAG07475.1 - 0.0059 15.8 0.0 0.093 11.9 0.0 2.3 3 0 0 3 3 3 1 Aminotransferase class I and II TatD_DNase PF01026.21 AAG07475.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase adh_short_C2 PF13561.6 AAG07476.1 - 1e-61 208.5 2.5 1.3e-61 208.2 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG07476.1 - 5.1e-51 172.9 0.2 5.8e-51 172.7 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG07476.1 - 3.4e-13 49.9 1.0 4.8e-13 49.4 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG07476.1 - 0.00043 19.8 0.3 0.00071 19.1 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 AAG07476.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MccV PF17508.2 AAG07476.1 - 0.037 14.6 0.3 0.084 13.4 0.3 1.7 1 0 0 1 1 1 0 Microcin V bacteriocin 2-Hacid_dh_C PF02826.19 AAG07476.1 - 0.1 12.0 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAG07476.1 - 0.12 12.2 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 AAG07476.1 - 0.17 10.9 0.3 0.26 10.3 0.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF2218 PF09981.9 AAG07477.1 - 1.4e-29 102.3 0.2 1.6e-29 102.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2218) Phage_GPD PF05954.11 AAG07477.1 - 0.11 11.8 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) HpaB_N PF11794.8 AAG07478.1 - 3.9e-93 312.1 0.0 4.8e-93 311.8 0.0 1.1 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 AAG07478.1 - 2.9e-62 209.4 0.0 3.9e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Flavin_Reduct PF01613.18 AAG07479.1 - 3.4e-28 98.6 0.0 3.9e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain VasI PF11319.8 AAG07479.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 4HBT PF03061.22 AAG07480.1 - 7.2e-13 48.7 0.8 9.3e-13 48.3 0.1 1.5 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAG07480.1 - 0.00019 21.8 0.3 0.00022 21.6 0.3 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily HTH_18 PF12833.7 AAG07481.1 - 1.4e-25 89.4 4.1 3.5e-25 88.1 4.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07481.1 - 1.4e-16 60.1 0.0 5.1e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 AAG07481.1 - 9.6e-15 54.7 1.3 6.2e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 AraC-binding-like domain AraC_binding PF02311.19 AAG07481.1 - 0.034 14.1 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG07482.1 - 2.7e-07 30.2 1.0 4.5e-07 29.5 1.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 AAG07482.1 - 0.00015 21.6 0.1 0.00022 21.1 0.1 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain MFS_1 PF07690.16 AAG07483.1 - 3e-48 164.6 48.9 2.2e-47 161.7 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG07483.1 - 7e-13 48.2 26.5 8.3e-13 48.0 2.9 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAG07483.1 - 8.2e-09 34.8 10.5 0.0021 17.0 2.1 3.6 1 1 2 3 3 3 3 MFS_1 like family Nuc_H_symport PF03825.16 AAG07483.1 - 2e-07 30.3 7.3 3.3e-07 29.7 7.3 1.3 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 AAG07483.1 - 0.0027 16.5 17.1 0.008 15.0 1.9 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter OATP PF03137.20 AAG07483.1 - 6.9 4.8 19.2 0.88 7.8 0.8 3.7 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family ADH_N PF08240.12 AAG07484.1 - 5.2e-33 113.2 0.4 7.9e-33 112.6 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAG07484.1 - 1.2e-23 83.5 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AAG07484.1 - 4.2e-05 23.1 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AAG07484.1 - 9.5e-05 23.5 0.1 0.00016 22.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DZR PF12773.7 AAG07484.1 - 0.016 15.2 1.6 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon adh_short_C2 PF13561.6 AAG07485.1 - 1.4e-57 195.0 0.0 1.7e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG07485.1 - 2.9e-45 154.1 0.0 3.6e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAG07485.1 - 7e-10 38.8 0.1 3.1e-09 36.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAG07485.1 - 1.9e-05 24.6 0.2 0.00014 21.9 0.2 1.9 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 AAG07485.1 - 0.00024 20.3 0.0 0.00035 19.8 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Oxidored_nitro PF00148.19 AAG07485.1 - 0.074 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase GDP_Man_Dehyd PF16363.5 AAG07485.1 - 0.17 11.2 0.1 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 AAG07485.1 - 0.2 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein OprB PF04966.12 AAG07486.1 - 5e-68 230.2 0.7 6.1e-68 229.9 0.7 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family GMC_oxred_N PF00732.19 AAG07487.1 - 2.2e-86 289.9 0.0 3e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AAG07487.1 - 2.2e-43 148.2 0.0 3.5e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 AAG07487.1 - 1.1e-06 28.0 0.2 1.7e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 AAG07487.1 - 1e-05 24.9 0.7 0.021 13.9 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 AAG07487.1 - 0.0061 16.2 2.7 0.048 13.2 2.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG07487.1 - 0.016 15.4 0.1 0.043 14.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG07487.1 - 0.026 13.7 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG07487.1 - 0.032 13.5 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Response_reg PF00072.24 AAG07488.1 - 2.1e-30 105.1 0.2 3.1e-30 104.6 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG07488.1 - 7.3e-22 77.3 0.1 1.9e-21 75.9 0.1 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AAG07489.1 - 5e-22 78.5 0.0 2.7e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAG07489.1 - 8.8e-09 35.3 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAG07489.1 - 1.5e-06 28.5 0.4 3.9e-06 27.1 0.4 1.8 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 AAG07489.1 - 2.2e-05 24.4 0.0 6.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Ferric_reduct PF01794.19 AAG07490.1 - 4.7e-07 30.0 6.7 4.7e-07 30.0 6.7 2.3 2 1 0 3 3 3 1 Ferric reductase like transmembrane component K_trans PF02705.16 AAG07490.1 - 0.31 9.5 4.1 0.071 11.6 0.5 1.6 2 0 0 2 2 2 0 K+ potassium transporter DoxX PF07681.12 AAG07491.1 - 2.9e-20 72.6 2.7 2.9e-20 72.6 2.7 1.7 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 AAG07491.1 - 0.00034 20.6 6.1 0.045 13.6 4.2 2.9 2 1 0 2 2 2 2 TQO small subunit DoxD DUF2063 PF09836.9 AAG07492.1 - 1.9e-22 79.3 0.1 3.4e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Putative DNA-binding domain FWWh PF14922.6 AAG07492.1 - 0.22 11.4 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF692 PF05114.13 AAG07493.1 - 2.4e-97 325.3 0.0 2.7e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) BMFP PF04380.13 AAG07493.1 - 0.26 11.8 2.2 0.53 10.8 2.2 1.5 1 0 0 1 1 1 0 Membrane fusogenic activity EF-hand_5 PF13202.6 AAG07494.1 - 1.5e-09 36.9 0.2 0.00072 19.0 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 AAG07494.1 - 4.4e-09 35.2 0.3 0.00053 19.4 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 AAG07494.1 - 7e-09 36.0 0.0 0.0052 17.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AAG07494.1 - 2.1e-08 33.4 0.1 0.0076 16.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 AAG07494.1 - 4.4e-05 23.2 0.2 0.0082 16.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair GETHR PF05671.11 AAG07494.1 - 0.69 9.3 6.9 5.8 6.4 2.2 2.3 2 0 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) DUF3391 PF11871.8 AAG07495.1 - 1.5e-35 122.7 0.0 2.2e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) HD PF01966.22 AAG07495.1 - 3.2e-15 56.4 0.0 5.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AAG07495.1 - 1.1e-13 51.3 0.0 3e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 AAG07495.1 - 2.2e-05 24.0 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 HDOD domain LysR_substrate PF03466.20 AAG07496.1 - 1.4e-34 119.3 5.4 1.9e-34 118.8 5.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07496.1 - 1.6e-20 72.8 1.5 3.3e-20 71.8 1.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Beta-lactamase PF00144.24 AAG07497.1 - 5.9e-80 269.0 3.4 6.7e-80 268.8 3.4 1.0 1 0 0 1 1 1 1 Beta-lactamase Sigma70_r1_2 PF00140.20 AAG07498.1 - 0.031 14.3 2.4 0.082 12.9 2.4 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 CHASE PF03924.13 AAG07499.1 - 2.1e-45 155.0 2.0 1e-44 152.7 0.3 2.9 2 0 0 2 2 2 1 CHASE domain Response_reg PF00072.24 AAG07499.1 - 2e-41 140.7 0.0 9.5e-25 87.0 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain PAS PF00989.25 AAG07499.1 - 4.6e-33 113.6 0.2 7.9e-15 54.8 0.0 3.9 3 1 0 3 3 3 3 PAS fold HATPase_c PF02518.26 AAG07499.1 - 3.7e-31 107.9 0.0 7.1e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAG07499.1 - 2.4e-29 101.4 0.0 3.6e-17 62.4 0.0 4.2 4 1 0 4 4 4 3 PAS fold PAS_9 PF13426.7 AAG07499.1 - 3.2e-28 98.0 0.0 5.7e-12 45.8 0.0 4.1 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.10 AAG07499.1 - 1.1e-26 93.3 7.4 1.1e-11 45.0 0.0 5.1 5 0 0 5 5 5 3 PAS fold HisKA PF00512.25 AAG07499.1 - 1.8e-18 66.3 3.0 2.2e-18 66.1 0.3 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AAG07499.1 - 5.1e-15 55.5 2.3 3.1e-14 53.0 2.3 2.5 1 0 0 1 1 1 1 Hpt domain PAS_8 PF13188.7 AAG07499.1 - 2e-13 50.0 1.6 0.00014 21.8 0.0 4.3 4 0 0 4 4 3 3 PAS domain PAS_6 PF08348.11 AAG07499.1 - 0.01 15.7 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 YheO-like PAS domain MFS_1 PF07690.16 AAG07500.1 - 1.3e-32 113.1 52.0 1.3e-32 113.1 52.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG07500.1 - 0.00016 20.7 10.4 0.00016 20.7 10.4 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AAG07500.1 - 0.025 13.9 37.1 0.031 13.6 37.1 1.2 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Acetyltransf_1 PF00583.25 AAG07501.1 - 8.6e-13 48.5 0.1 1e-12 48.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG07501.1 - 6.1e-07 29.4 0.1 7.8e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG07501.1 - 4.9e-06 26.9 0.2 6.6e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAG07501.1 - 4.5e-05 24.1 0.0 7.1e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG07501.1 - 0.00073 19.2 0.1 0.0011 18.6 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG07501.1 - 0.002 18.1 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 AAG07501.1 - 0.033 13.6 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 AAG07501.1 - 0.047 13.8 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3412 PF11892.8 AAG07502.1 - 3.8e-56 188.4 0.0 6.7e-56 187.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3412) DUF4478 PF14793.6 AAG07502.1 - 2.9e-45 152.6 0.0 2e-44 149.9 0.0 2.1 2 0 0 2 2 2 1 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Lysine_decarbox PF03641.14 AAG07502.1 - 1.3e-31 109.4 0.0 2.1e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AAG07502.1 - 1.5e-06 27.8 0.1 2.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Heme_oxygenase PF01126.20 AAG07503.1 - 2.2e-34 119.1 0.0 2.4e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Heme oxygenase PHY PF00360.20 AAG07504.1 - 5.3e-48 162.7 0.0 1.1e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.26 AAG07504.1 - 1.7e-18 67.6 0.1 1e-17 65.0 0.0 2.4 2 0 0 2 2 2 1 GAF domain HATPase_c PF02518.26 AAG07504.1 - 3.3e-13 50.1 0.0 7.1e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG07504.1 - 1.3e-11 44.4 2.8 1.3e-11 44.4 2.8 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 AAG07504.1 - 9.3e-11 42.4 0.2 4.8e-10 40.1 0.0 2.3 2 1 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 AAG07504.1 - 0.0094 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 GHKL domain DUF2964 PF11177.8 AAG07505.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) APH PF01636.23 AAG07506.1 - 4.2e-35 121.8 13.7 5e-35 121.6 13.7 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 AAG07506.1 - 0.041 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase HTH_18 PF12833.7 AAG07507.1 - 6.9e-17 61.5 0.1 1.3e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AAG07507.1 - 5.2e-15 55.5 0.1 9.5e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_AraC PF00165.23 AAG07507.1 - 2.4e-07 30.7 0.1 5.4e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG07507.1 - 1.3e-05 24.8 0.2 2.3e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AAG07507.1 - 0.036 13.8 4.3 0.68 9.6 4.3 2.1 1 1 0 1 1 1 0 Cupin FAA_hydrolase PF01557.18 AAG07508.1 - 6.7e-51 173.0 0.0 7.7e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.18 AAG07509.1 - 3.5e-57 193.6 0.0 4.3e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldedh PF00171.22 AAG07510.1 - 1.4e-174 580.9 0.0 1.6e-174 580.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AAG07510.1 - 0.18 11.2 0.0 9.2 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LigB PF02900.18 AAG07511.1 - 9.1e-80 267.6 0.0 1e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CHMI PF02962.15 AAG07512.1 - 4.4e-50 169.2 0.0 4.9e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 5-carboxymethyl-2-hydroxymuconate isomerase TetR_C_4 PF08359.11 AAG07512.1 - 0.066 13.4 0.3 0.13 12.5 0.2 1.5 1 1 0 1 1 1 0 YsiA-like protein, C-terminal region MFS_1 PF07690.16 AAG07513.1 - 1.4e-56 192.0 76.9 2.8e-49 167.9 45.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG07513.1 - 0.038 13.3 33.2 0.47 9.7 33.2 2.0 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 AAG07513.1 - 0.73 8.4 12.7 0.095 11.3 0.8 3.4 3 1 1 4 4 4 0 Vacuole effluxer Atg22 like FAA_hydrolase PF01557.18 AAG07514.1 - 1.6e-07 31.2 0.0 2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HpcH_HpaI PF03328.14 AAG07515.1 - 4.3e-62 209.1 0.0 4.8e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 AAG07515.1 - 0.0075 15.2 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain DUF2156 PF09924.9 AAG07515.1 - 0.018 14.0 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) DUF934 PF06073.12 AAG07516.1 - 9.7e-39 131.6 0.0 1.2e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF934) NIR_SIR PF01077.22 AAG07517.1 - 1e-54 184.4 0.0 8.2e-39 132.7 0.0 3.1 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAG07517.1 - 2.7e-37 126.5 0.0 3.2e-18 65.4 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain zf-HC2 PF13490.6 AAG07517.1 - 8.2 6.8 8.7 0.75 10.1 0.1 3.5 4 0 0 4 4 4 0 Putative zinc-finger Fer4_18 PF13746.6 AAG07518.1 - 3.9e-45 152.7 7.5 7.2e-45 151.8 7.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain FixG_C PF11614.8 AAG07518.1 - 2e-27 95.8 0.0 2.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fer4_7 PF12838.7 AAG07518.1 - 7e-10 39.3 6.3 4.8e-05 23.9 1.4 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG07518.1 - 3.7e-09 36.9 5.0 2.2e-05 24.8 1.3 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG07518.1 - 1.6e-08 34.6 11.0 8e-06 25.9 1.8 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG07518.1 - 2.1e-08 34.6 10.2 8.9e-06 26.2 1.1 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG07518.1 - 1.3e-06 28.4 11.5 9.2e-05 22.5 1.9 2.7 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_5 PF12801.7 AAG07518.1 - 5.9e-05 22.9 10.0 5.9e-05 22.9 10.0 3.9 5 0 0 5 5 4 1 4Fe-4S binding domain Fer4 PF00037.27 AAG07518.1 - 0.0007 19.3 24.6 0.0012 18.6 3.6 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAG07518.1 - 0.015 16.2 4.9 0.015 16.2 4.9 3.7 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 AAG07518.1 - 0.02 15.8 16.4 0.03 15.3 4.1 3.1 1 1 2 3 3 3 0 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AAG07518.1 - 0.055 13.6 19.5 0.11 12.7 3.0 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain SpoIIM PF01944.17 AAG07518.1 - 0.08 13.0 2.6 0.23 11.5 2.5 1.8 1 1 0 1 1 1 0 Stage II sporulation protein M Fer4_21 PF14697.6 AAG07518.1 - 0.51 10.5 20.6 3.2 7.9 7.8 3.1 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAG07518.1 - 0.93 10.1 16.8 0.31 11.6 1.4 3.4 4 0 0 4 4 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AAG07518.1 - 0.95 10.2 12.6 3.3 8.5 2.9 2.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 AAG07518.1 - 1.9 9.2 27.2 0.057 14.0 3.4 3.3 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAG07518.1 - 4.1 7.6 24.5 0.86 9.8 4.9 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Aminotran_1_2 PF00155.21 AAG07519.1 - 4.1e-24 85.4 0.0 6e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAG07519.1 - 4.5e-14 51.8 0.0 1.1e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 AAG07519.1 - 8.7e-06 24.8 0.0 4.6e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_psq PF05225.16 AAG07519.1 - 0.019 14.7 0.2 0.056 13.2 0.2 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain CobT_C PF11775.8 AAG07519.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain COX1 PF00115.20 AAG07520.1 - 3.2e-110 368.9 64.5 3.2e-110 368.9 64.5 1.5 1 1 1 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I Saf_2TM PF18303.1 AAG07520.1 - 1.9 8.1 4.5 17 4.9 0.4 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain MarR PF01047.22 AAG07522.1 - 9.5e-16 57.5 0.1 1.6e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAG07522.1 - 3.9e-06 27.3 0.1 8.9e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AAG07522.1 - 1.2e-05 25.1 0.2 1.9e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AAG07522.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 AAG07522.1 - 0.0008 19.2 0.2 0.0014 18.5 0.1 1.5 1 1 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AAG07522.1 - 0.0017 18.3 0.1 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family EcoEI_R_C PF08463.10 AAG07522.1 - 0.059 13.5 0.7 4.5 7.4 0.1 2.1 2 0 0 2 2 2 0 EcoEI R protein C-terminal TFIIE_alpha PF02002.17 AAG07522.1 - 0.082 12.8 0.2 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 TFIIE alpha subunit HTH_IclR PF09339.10 AAG07522.1 - 0.086 12.7 1.3 0.74 9.7 0.0 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain Penicillinase_R PF03965.16 AAG07522.1 - 0.11 12.9 0.3 0.18 12.2 0.3 1.5 1 1 0 1 1 1 0 Penicillinase repressor CwfJ_C_2 PF04676.14 AAG07522.1 - 0.12 13.3 0.0 0.17 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 MFS_1 PF07690.16 AAG07523.1 - 1.8e-42 145.5 91.7 2.4e-40 138.5 48.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG07523.1 - 1.1e-11 44.4 25.6 4.9e-11 42.2 9.0 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 AAG07523.1 - 1.9e-07 29.9 1.3 1.9e-07 29.9 1.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 AAG07523.1 - 2.3e-07 29.7 16.7 0.00011 20.9 8.0 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 AAG07523.1 - 0.12 11.2 14.3 0.07 12.0 2.0 2.3 1 1 1 2 2 2 0 MFS_1 like family BT1 PF03092.16 AAG07523.1 - 0.52 8.5 6.2 0.37 9.0 3.9 1.9 2 0 0 2 2 2 0 BT1 family OprD PF03573.13 AAG07524.1 - 2.8e-149 497.5 1.5 3.1e-149 497.3 1.5 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family tRNA-synt_1b PF00579.25 AAG07525.1 - 1.2e-66 225.0 0.0 1.5e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 AAG07525.1 - 0.00079 19.1 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 S4 domain L_biotic_typeA PF04604.13 AAG07526.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Type-A lantibiotic Chol_subst-bind PF09129.11 AAG07527.1 - 6.5e-159 528.0 0.0 8e-159 527.7 0.0 1.1 1 0 0 1 1 1 1 Cholesterol oxidase, substrate-binding FAD_binding_4 PF01565.23 AAG07527.1 - 3.1e-13 49.7 0.1 1.2e-12 47.7 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain TAT_signal PF10518.9 AAG07527.1 - 0.0016 18.2 2.4 0.0059 16.4 2.4 2.1 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Bacteriocin_IIc PF10439.9 AAG07528.1 - 0.0003 20.9 25.5 0.069 13.3 25.5 2.1 1 1 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide MccV PF17508.2 AAG07528.1 - 0.58 10.7 11.3 0.11 13.1 3.7 2.1 1 1 1 2 2 2 0 Microcin V bacteriocin Kinocilin PF15033.6 AAG07528.1 - 0.77 9.4 5.6 0.21 11.2 2.6 1.5 1 1 1 2 2 2 0 Kinocilin protein Gly-zipper_YMGG PF13441.6 AAG07528.1 - 3.2 7.6 30.1 1.9e+02 1.9 30.0 2.3 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 AAG07528.1 - 9.6 6.2 25.9 2.7 7.9 2.5 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain HlyD_3 PF13437.6 AAG07529.1 - 1.9e-18 67.1 0.1 1.3e-13 51.5 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAG07529.1 - 3.6e-13 49.2 3.3 2.8e-08 33.2 1.1 2.3 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAG07529.1 - 2.4e-09 36.9 6.2 4.8e-09 36.0 6.1 1.7 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG07529.1 - 8e-06 25.6 0.0 0.05 13.4 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAG07529.1 - 1e-05 25.3 0.2 0.00012 21.8 0.1 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like Baculo_PEP_C PF04513.12 AAG07529.1 - 0.028 14.4 4.8 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 AAG07529.1 - 0.044 13.4 17.7 2.5 7.6 17.7 2.1 1 1 0 1 1 1 0 Intermediate filament protein Phage_GP20 PF06810.11 AAG07529.1 - 0.12 12.2 7.6 0.11 12.3 1.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 SPX PF03105.19 AAG07529.1 - 0.14 12.1 4.2 0.19 11.6 4.2 1.2 1 0 0 1 1 1 0 SPX domain Spc7 PF08317.11 AAG07529.1 - 0.16 10.8 20.0 0.42 9.5 7.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 AAG07529.1 - 0.22 9.0 13.7 0.32 8.5 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 AAG07529.1 - 0.36 10.4 9.5 0.58 9.7 9.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRP1_N PF06424.12 AAG07529.1 - 2.4 8.5 7.3 2.9 8.3 0.6 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF4618 PF15397.6 AAG07529.1 - 4.3 6.7 15.6 2.2 7.6 7.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) CCDC-167 PF15188.6 AAG07529.1 - 5.5 7.4 12.4 6.6 7.1 0.5 3.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 FAM76 PF16046.5 AAG07529.1 - 6.4 6.0 10.1 12 5.1 0.6 2.0 1 1 1 2 2 2 0 FAM76 protein DUF4355 PF14265.6 AAG07529.1 - 8.1 6.7 12.0 4.5 7.5 1.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4355) ABC_membrane PF00664.23 AAG07530.1 - 1.2e-38 133.3 8.7 1.8e-38 132.8 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C39 PF03412.15 AAG07530.1 - 2.6e-37 127.6 0.0 4.6e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C39 family ABC_tran PF00005.27 AAG07530.1 - 7.2e-29 101.1 0.0 1.2e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAG07530.1 - 6.6e-07 29.0 0.1 0.00061 19.3 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain Peptidase_C70 PF12385.8 AAG07530.1 - 1e-06 28.8 0.0 4.9e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Mg_chelatase PF01078.21 AAG07530.1 - 0.00028 20.4 0.0 0.00063 19.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AAG07530.1 - 0.00046 20.1 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAG07530.1 - 0.0026 17.5 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAG07530.1 - 0.0043 17.1 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AAG07530.1 - 0.0095 16.3 0.3 0.025 15.0 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAG07530.1 - 0.031 14.1 0.0 0.36 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AAG07530.1 - 0.033 14.6 0.0 0.23 11.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAG07530.1 - 0.04 14.2 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAG07530.1 - 0.041 14.4 0.0 0.068 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG07530.1 - 0.051 13.8 0.1 0.46 10.7 0.0 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 AAG07530.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain OEP PF02321.18 AAG07531.1 - 1.9e-52 177.8 38.6 6.6e-27 94.5 16.7 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein LysR_substrate PF03466.20 AAG07532.1 - 1.6e-35 122.4 4.8 2.2e-35 121.9 4.8 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07532.1 - 3.3e-15 55.8 0.7 6.1e-15 54.9 0.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAG07532.1 - 0.14 11.7 0.1 0.37 10.4 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma54_activat PF00158.26 AAG07534.1 - 3.7e-62 209.0 0.0 1.2e-61 207.4 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG07534.1 - 1.3e-23 83.6 0.0 4.5e-23 81.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain GAF PF01590.26 AAG07534.1 - 1.4e-08 35.5 0.3 4.5e-08 33.8 0.3 1.8 1 0 0 1 1 1 1 GAF domain HTH_8 PF02954.19 AAG07534.1 - 1.4e-08 34.4 0.8 3.1e-08 33.3 0.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family PAS_4 PF08448.10 AAG07534.1 - 1.8e-06 28.1 2.0 0.0021 18.3 0.0 3.5 3 1 0 3 3 2 2 PAS fold HTH_23 PF13384.6 AAG07534.1 - 0.0002 21.1 1.0 0.0006 19.5 1.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AAG07534.1 - 0.00046 20.3 0.8 0.0016 18.5 0.8 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain IclR PF01614.18 AAG07534.1 - 0.0016 18.2 0.0 0.0092 15.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_30 PF13556.6 AAG07534.1 - 0.0018 18.0 0.5 0.0075 16.1 0.5 2.1 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA_5 PF07728.14 AAG07534.1 - 0.0031 17.5 0.0 0.0075 16.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) HTH_50 PF18024.1 AAG07534.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain RWP-RK PF02042.15 AAG07534.1 - 0.0062 16.5 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 RWP-RK domain PAS PF00989.25 AAG07534.1 - 0.0075 16.3 0.0 0.22 11.5 0.0 2.9 4 0 0 4 4 3 1 PAS fold HTH_29 PF13551.6 AAG07534.1 - 0.0093 16.0 0.3 0.037 14.0 0.3 2.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_17 PF12728.7 AAG07534.1 - 0.012 15.8 0.1 0.031 14.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 AAG07534.1 - 0.028 14.1 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_1 PF00126.27 AAG07534.1 - 0.037 14.0 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_7 PF02796.15 AAG07534.1 - 0.041 14.0 0.7 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase NACHT PF05729.12 AAG07534.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_2 PF07724.14 AAG07534.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_22 PF13309.6 AAG07534.1 - 0.21 11.7 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 HTH domain adh_short PF00106.25 AAG07535.1 - 8.3e-62 208.1 0.3 1.1e-61 207.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG07535.1 - 7.1e-61 205.7 2.5 1.4e-60 204.8 2.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG07535.1 - 2.1e-13 50.6 0.8 3.4e-13 49.9 0.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 AAG07535.1 - 0.00015 21.7 0.6 0.00026 20.9 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AAG07535.1 - 0.0015 18.6 0.3 0.0044 17.1 0.2 1.8 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CbiA PF01656.23 AAG07535.1 - 0.019 15.1 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 3Beta_HSD PF01073.19 AAG07535.1 - 0.065 12.2 0.2 0.12 11.4 0.1 1.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_kinase PF01513.21 AAG07536.1 - 1.2e-16 60.8 0.0 1.2e-15 57.5 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AAG07536.1 - 5.4e-06 26.0 0.0 2.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain E1_dh PF00676.20 AAG07537.1 - 1.5e-97 326.2 0.1 1.8e-97 326.0 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 AAG07537.1 - 0.00011 21.5 0.5 0.00019 20.7 0.5 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AAG07537.1 - 0.00012 21.9 5.9 0.00053 19.8 4.1 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 AAG07537.1 - 0.0012 17.8 0.1 0.0022 17.0 0.1 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain ACP PF06857.11 AAG07537.1 - 0.071 13.4 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Transket_pyr PF02779.24 AAG07538.1 - 4.8e-56 189.2 0.0 7.7e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAG07538.1 - 4.9e-44 149.2 0.0 7.6e-44 148.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AAG07538.1 - 0.0018 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Abhydrolase_1 PF00561.20 AAG07539.1 - 2.5e-26 92.9 0.0 5e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG07539.1 - 3.1e-23 83.6 3.9 5.1e-23 82.8 3.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Biotin_lipoyl PF00364.22 AAG07539.1 - 2e-14 53.2 0.0 3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Hydrolase_4 PF12146.8 AAG07539.1 - 8.3e-11 41.6 0.2 1.8e-10 40.5 0.2 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAG07539.1 - 3.3e-06 27.4 0.0 5.1e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 AAG07539.1 - 0.00094 19.0 0.0 0.31 10.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.20 AAG07539.1 - 0.0013 18.5 0.1 0.0041 16.8 0.1 1.7 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 AAG07539.1 - 0.0018 17.0 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family GCV_H PF01597.19 AAG07539.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein Abhydrolase_3 PF07859.13 AAG07539.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 AAG07539.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.5 2 0 0 2 2 2 0 PGAP1-like protein AXE1 PF05448.12 AAG07539.1 - 0.056 12.1 0.0 0.12 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.13 AAG07539.1 - 0.074 11.5 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 AAG07539.1 - 0.095 12.6 0.1 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_2 PF02230.16 AAG07539.1 - 0.13 12.1 0.1 9.7 5.9 0.0 3.0 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase ADH_N PF08240.12 AAG07540.1 - 1.3e-32 111.9 0.5 3e-32 110.7 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAG07540.1 - 2.8e-26 92.0 0.4 2.8e-26 92.0 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AAG07540.1 - 3.5e-08 33.2 0.4 5.4e-08 32.6 0.4 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 AAG07540.1 - 1.4e-06 28.1 0.1 2.7e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 AAG07540.1 - 0.0005 21.1 0.0 0.00095 20.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAG07540.1 - 0.0009 18.6 1.6 0.0016 17.8 1.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AAG07540.1 - 0.01 15.2 0.2 0.02 14.3 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 AAG07540.1 - 0.012 15.3 0.9 0.017 14.8 0.9 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAG07540.1 - 0.032 13.5 2.1 0.078 12.2 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG07540.1 - 0.042 13.4 0.3 0.087 12.4 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SH3_3 PF08239.11 AAG07541.1 - 1.3e-10 41.4 0.2 3.2e-10 40.1 0.3 1.6 2 0 0 2 2 1 1 Bacterial SH3 domain SKA2 PF16740.5 AAG07541.1 - 0.0003 20.5 1.1 0.16 11.8 0.4 2.1 1 1 1 2 2 2 2 Spindle and kinetochore-associated protein 2 SH3_4 PF06347.13 AAG07541.1 - 0.00068 19.4 0.1 0.0023 17.7 0.0 1.9 1 1 1 2 2 2 1 Bacterial SH3 domain ATG16 PF08614.11 AAG07541.1 - 0.00097 19.4 4.6 0.0092 16.2 4.7 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) FliT PF05400.13 AAG07541.1 - 0.0012 19.6 3.2 0.002 18.9 3.2 1.3 1 0 0 1 1 1 1 Flagellar protein FliT Filament PF00038.21 AAG07541.1 - 0.0038 16.9 0.1 0.0046 16.6 0.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein Atg14 PF10186.9 AAG07541.1 - 0.0066 15.6 0.2 0.0089 15.1 0.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 AAG07541.1 - 0.013 15.0 0.4 0.017 14.6 0.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 AAG07541.1 - 0.02 14.3 2.3 0.025 13.9 0.8 1.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cluap1 PF10234.9 AAG07541.1 - 0.022 14.2 0.3 0.029 13.8 0.3 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 PRKG1_interact PF15898.5 AAG07541.1 - 0.027 15.3 1.4 0.043 14.7 1.4 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain HMMR_N PF15905.5 AAG07541.1 - 0.051 13.1 0.2 0.066 12.7 0.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 AAG07541.1 - 0.054 13.5 1.8 0.091 12.8 1.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 AAG07541.1 - 0.074 13.2 1.2 0.1 12.7 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4455 PF14643.6 AAG07541.1 - 0.074 11.7 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF4164 PF13747.6 AAG07541.1 - 0.085 13.1 3.2 0.14 12.5 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3584 PF12128.8 AAG07541.1 - 0.087 10.3 0.6 0.11 10.0 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5082 PF16888.5 AAG07541.1 - 0.09 13.1 1.2 3.8 7.8 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 AAG07541.1 - 0.098 12.7 0.5 0.16 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Noelin-1 PF12308.8 AAG07541.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein Spc7 PF08317.11 AAG07541.1 - 0.11 11.3 1.5 0.15 10.9 1.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 AAG07541.1 - 0.12 10.9 1.5 0.18 10.3 1.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Herpes_UL25 PF01499.16 AAG07541.1 - 0.12 10.8 0.4 0.16 10.4 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family OmpH PF03938.14 AAG07541.1 - 0.15 12.4 2.3 0.23 11.8 2.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TTRAP PF14203.6 AAG07541.1 - 0.19 11.7 0.1 0.39 10.7 0.1 1.6 1 1 0 1 1 1 0 Putative tranposon-transfer assisting protein YkyA PF10368.9 AAG07541.1 - 0.2 11.3 0.3 0.26 10.9 0.3 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.12 AAG07541.1 - 0.23 11.5 2.6 0.35 10.9 0.9 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 AAG07541.1 - 0.24 11.9 0.8 0.58 10.7 0.8 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 AAG07541.1 - 0.24 11.2 3.4 6 6.7 1.1 2.3 1 1 1 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 AAG07541.1 - 0.35 11.1 3.9 2.6 8.4 1.4 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain CHASE3 PF05227.13 AAG07541.1 - 0.4 10.6 5.5 0.62 10.0 5.5 1.2 1 0 0 1 1 1 0 CHASE3 domain DUF4407 PF14362.6 AAG07541.1 - 0.44 9.9 7.5 0.073 12.4 2.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF349 PF03993.12 AAG07541.1 - 0.86 10.0 3.5 3 8.2 3.5 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) DUF4140 PF13600.6 AAG07541.1 - 1.3 9.5 4.3 68 4.0 4.3 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 AAG07541.1 - 1.5 9.5 3.4 21 5.8 3.4 2.2 1 1 0 1 1 1 0 SlyX DUF883 PF05957.13 AAG07541.1 - 4.7 7.9 8.3 26 5.5 7.8 2.6 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF883) Bac_luciferase PF00296.20 AAG07542.1 - 6.6e-51 173.6 4.8 9.9e-51 173.0 4.8 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase TonB_dep_Rec PF00593.24 AAG07543.1 - 1.2e-44 154.0 27.1 1.2e-44 154.0 27.1 2.2 1 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG07543.1 - 4.6e-12 46.5 2.2 1.5e-11 44.8 2.2 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OmpA_membrane PF01389.17 AAG07543.1 - 6e-05 22.8 0.4 0.00014 21.6 0.4 1.6 1 0 0 1 1 1 1 OmpA-like transmembrane domain DUF560 PF04575.13 AAG07543.1 - 0.00012 21.6 0.3 0.77 9.1 0.0 3.1 3 1 1 4 4 4 2 Protein of unknown function (DUF560) OMP_b-brl PF13505.6 AAG07543.1 - 0.00077 19.6 14.6 0.18 11.9 3.3 3.8 1 1 3 4 4 4 4 Outer membrane protein beta-barrel domain Opacity PF02462.15 AAG07543.1 - 0.0076 16.4 0.5 1 9.5 0.0 3.2 3 0 0 3 3 3 1 Opacity family porin protein DUF481 PF04338.12 AAG07543.1 - 0.018 15.1 0.2 0.018 15.1 0.2 3.3 2 1 0 2 2 2 0 Protein of unknown function, DUF481 HTH_IclR PF09339.10 AAG07544.1 - 3.1e-15 55.7 0.4 6.6e-15 54.7 0.4 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain IclR PF01614.18 AAG07544.1 - 1.5e-07 31.3 0.0 3.4e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Bacterial transcriptional regulator MarR_2 PF12802.7 AAG07544.1 - 0.00012 21.8 0.2 0.00032 20.5 0.2 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAG07544.1 - 0.0044 16.5 0.1 0.0092 15.5 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAG07544.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AAG07544.1 - 0.073 13.0 0.2 0.62 10.0 0.0 2.5 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 AAG07544.1 - 0.076 13.4 0.2 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator HTH_29 PF13551.6 AAG07544.1 - 0.076 13.0 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn helix ABC_tran PF00005.27 AAG07545.1 - 1.8e-29 103.0 0.0 2.3e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07545.1 - 1.1e-11 45.2 0.6 1e-05 25.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG07545.1 - 5.7e-10 39.0 0.0 0.00028 20.4 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAG07545.1 - 3.5e-07 30.3 0.0 6.8e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 AAG07545.1 - 1.2e-05 24.4 0.0 0.0012 17.7 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_27 PF13514.6 AAG07545.1 - 2.7e-05 23.8 0.0 7.1e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAG07545.1 - 3e-05 24.5 1.0 8.3e-05 23.0 0.9 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG07545.1 - 3.7e-05 23.4 0.0 7.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2813 PF11398.8 AAG07545.1 - 0.00022 20.6 0.0 0.00059 19.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_25 PF13481.6 AAG07545.1 - 0.00071 19.2 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAG07545.1 - 0.00087 19.8 0.0 0.0013 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAG07545.1 - 0.0047 16.3 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAG07545.1 - 0.021 14.7 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 AAG07545.1 - 0.026 14.8 0.1 0.067 13.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 AAG07545.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAG07545.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAG07545.1 - 0.12 12.2 0.0 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AAG07545.1 - 0.13 12.5 0.1 0.94 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 AAG07545.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Adeno_IVa2 PF02456.15 AAG07545.1 - 0.22 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Peripla_BP_2 PF01497.18 AAG07546.1 - 1.3e-41 142.8 0.2 1.5e-41 142.6 0.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_4 PF13407.6 AAG07546.1 - 0.031 13.9 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF5304 PF17230.2 AAG07546.1 - 0.13 12.5 0.7 0.61 10.3 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5304) FecCD PF01032.18 AAG07547.1 - 5.1e-84 281.9 33.6 6.4e-84 281.6 33.6 1.0 1 0 0 1 1 1 1 FecCD transport family VirB8 PF04335.13 AAG07547.1 - 8.2 6.2 8.9 2.2 8.0 0.2 3.1 2 1 0 2 2 2 0 VirB8 protein FecCD PF01032.18 AAG07548.1 - 5.5e-77 258.8 37.5 7.1e-77 258.5 37.1 1.4 1 1 0 1 1 1 1 FecCD transport family adh_short_C2 PF13561.6 AAG07549.1 - 1.4e-50 172.0 0.0 1.9e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG07549.1 - 9.4e-41 139.4 0.1 3.7e-40 137.5 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG07549.1 - 1.3e-08 35.0 2.7 1.5e-06 28.3 2.7 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG07549.1 - 1.2e-07 31.5 0.0 2e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG07549.1 - 0.00012 21.3 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AAG07549.1 - 0.014 15.3 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Amidase PF01425.21 AAG07550.1 - 3.3e-56 191.2 2.9 5.9e-45 154.1 1.2 3.0 2 1 1 3 3 3 3 Amidase GGACT PF06094.12 AAG07551.1 - 5.7e-16 59.2 0.0 6.3e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Aminotran_1_2 PF00155.21 AAG07552.1 - 3.1e-18 66.1 0.0 5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAG07552.1 - 3.2e-17 61.9 0.1 9.9e-17 60.4 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAG07552.1 - 0.0058 16.6 0.1 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAG07552.1 - 0.035 14.0 1.0 0.098 12.6 0.1 2.3 2 0 0 2 2 2 0 MarR family Rrf2 PF02082.20 AAG07552.1 - 0.049 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Acetyltransf_1 PF00583.25 AAG07553.1 - 2.7e-17 63.1 0.2 3.5e-17 62.7 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG07553.1 - 6.5e-10 39.0 0.0 8.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG07553.1 - 1.2e-08 35.3 0.7 1.4e-08 35.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAG07553.1 - 0.00011 22.9 0.9 0.00013 22.6 0.9 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAG07553.1 - 0.00036 20.6 0.2 0.00048 20.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG07553.1 - 0.003 17.6 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AAG07553.1 - 0.0056 16.6 0.0 0.0088 16.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 AAG07553.1 - 0.067 12.9 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 AAG07553.1 - 0.14 12.3 3.0 0.21 11.8 2.9 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF832 PF05734.11 AAG07553.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Aldo_ket_red PF00248.21 AAG07554.1 - 2.1e-47 161.8 0.0 3e-45 154.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TonB_dep_Rec PF00593.24 AAG07555.1 - 9e-54 184.1 31.6 1.2e-53 183.6 31.6 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAG07555.1 - 1.6e-16 60.8 1.7 3.5e-16 59.7 1.7 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG07555.1 - 2.3e-05 24.1 0.0 6.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain Rrf2 PF02082.20 AAG07556.1 - 3.5e-23 81.7 0.1 6.2e-23 81.0 0.1 1.4 2 0 0 2 2 2 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AAG07556.1 - 3.1e-06 27.1 0.2 6.8e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAG07556.1 - 1.8e-05 24.6 0.1 0.00042 20.2 0.0 2.2 2 0 0 2 2 2 1 HTH domain HrcA_DNA-bdg PF03444.15 AAG07556.1 - 4.1e-05 23.1 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_IclR PF09339.10 AAG07556.1 - 0.0035 17.1 0.9 0.0066 16.2 0.1 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAG07556.1 - 0.0056 16.6 0.1 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 MarR family Put_DNA-bind_N PF06971.13 AAG07556.1 - 0.0065 16.5 0.0 0.026 14.6 0.0 1.9 1 1 1 2 2 2 1 Putative DNA-binding protein N-terminus GntR PF00392.21 AAG07556.1 - 0.048 13.3 0.2 0.14 11.8 0.0 1.9 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family Pyr_redox_2 PF07992.14 AAG07557.1 - 2.1e-18 66.6 0.0 3.3e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG07557.1 - 7.8e-05 22.1 0.0 0.69 9.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG07557.1 - 0.0001 21.1 0.1 0.038 12.7 0.1 2.6 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 AAG07557.1 - 0.0004 19.6 6.2 0.0019 17.3 0.5 3.0 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 AAG07557.1 - 0.0027 17.1 1.5 0.008 15.6 0.6 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG07557.1 - 0.013 15.7 0.2 0.047 13.9 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAG07557.1 - 0.015 14.6 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 AAG07557.1 - 0.025 13.7 0.1 0.092 11.8 0.2 1.8 1 1 1 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AAG07557.1 - 0.051 13.6 0.1 0.051 13.6 0.1 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 AAG07557.1 - 0.064 12.5 0.1 0.16 11.2 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 AAG07557.1 - 0.07 12.7 2.7 0.18 11.3 0.9 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Zn_Tnp_IS1595 PF12760.7 AAG07557.1 - 0.13 12.2 0.4 0.3 11.1 0.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DJ-1_PfpI PF01965.24 AAG07558.1 - 3e-39 134.5 0.0 3.4e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AAG07558.1 - 1.4e-05 24.9 0.0 0.057 13.1 0.0 2.2 1 1 1 2 2 2 2 ThiJ/PfpI family-like GATase_3 PF07685.14 AAG07558.1 - 0.00034 20.3 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DNA_pol3_delta PF06144.13 AAG07558.1 - 0.035 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Exo_endo_phos PF03372.23 AAG07559.1 - 5.2e-22 78.5 2.2 6e-22 78.3 2.2 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AAG07559.1 - 0.00017 21.4 0.0 0.0012 18.7 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Ribonuc_L-PSP PF01042.21 AAG07560.1 - 2.1e-25 89.1 0.0 2.4e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP LysR_substrate PF03466.20 AAG07561.1 - 1.6e-39 135.5 7.1 2.7e-39 134.7 7.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07561.1 - 7.3e-18 64.3 2.3 7.3e-18 64.3 2.3 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Sec8_exocyst PF04048.14 AAG07561.1 - 0.0062 16.4 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain ExbD PF02472.16 AAG07561.1 - 0.029 14.5 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR HTH_30 PF13556.6 AAG07561.1 - 0.039 13.7 0.9 0.092 12.6 0.9 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Sec34 PF04136.15 AAG07561.1 - 0.067 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Sec34-like family MarR_2 PF12802.7 AAG07561.1 - 0.073 13.0 2.6 0.079 12.9 0.3 2.2 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 AAG07561.1 - 0.1 12.4 0.3 0.1 12.4 0.3 2.2 2 1 0 2 2 2 0 IclR helix-turn-helix domain Rotamase_3 PF13616.6 AAG07563.1 - 3.4e-21 75.9 0.0 4.5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAG07563.1 - 7.2e-20 71.8 0.0 8.4e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAG07563.1 - 6.2e-05 23.8 0.0 6.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain GFA PF04828.14 AAG07564.1 - 1.3e-16 60.7 0.8 2e-16 60.1 0.8 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 AAG07564.1 - 0.0078 15.9 0.8 0.0078 15.9 0.8 3.0 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 AAG07564.1 - 0.04 13.8 0.1 0.04 13.8 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal PknG_rubred PF16919.5 AAG07564.1 - 0.18 12.0 0.0 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Methyltransf_25 PF13649.6 AAG07565.1 - 9.9e-12 45.4 0.0 2.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG07565.1 - 6.2e-10 39.6 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG07565.1 - 9.4e-09 35.2 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG07565.1 - 4.7e-08 33.0 0.0 6.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG07565.1 - 4.5e-07 30.5 0.0 8.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAG07565.1 - 0.00097 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family OprD PF03573.13 AAG07566.1 - 4.1e-142 473.9 2.9 4.6e-142 473.7 2.9 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family TPP_enzyme_N PF02776.18 AAG07567.1 - 1e-54 184.8 0.0 4.6e-53 179.3 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAG07567.1 - 5.7e-39 133.4 0.1 1.1e-38 132.5 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG07567.1 - 3.4e-30 104.6 0.1 5.8e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CoA_binding_2 PF13380.6 AAG07567.1 - 0.11 12.9 0.2 35 4.9 0.0 2.9 2 1 1 3 3 3 0 CoA binding domain B3_4 PF03483.17 AAG07568.1 - 2e-16 60.1 0.0 3.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain FMN_bind_2 PF04299.12 AAG07569.1 - 2.9e-64 215.8 0.0 3.5e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain F420H2_quin_red PF04075.14 AAG07569.1 - 0.045 13.9 0.4 1.7 8.8 0.4 2.2 1 1 0 1 1 1 0 F420H(2)-dependent quinone reductase Glyoxalase PF00903.25 AAG07570.1 - 0.029 14.6 0.0 0.24 11.6 0.0 2.0 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HTH_18 PF12833.7 AAG07571.1 - 1.1e-21 76.9 0.1 2.8e-21 75.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AAG07571.1 - 1.5e-17 63.9 0.0 2e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 AAG07571.1 - 3e-11 43.1 0.1 4.8e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Crp_2 PF13545.6 AAG07571.1 - 0.0055 16.7 0.1 0.018 15.0 0.1 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF3022 PF11226.8 AAG07571.1 - 0.054 13.9 0.2 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) FCD PF07729.12 AAG07572.1 - 2e-18 67.0 10.6 2e-18 67.0 10.6 1.5 1 1 0 1 1 1 1 FCD domain GntR PF00392.21 AAG07572.1 - 1e-10 41.1 0.1 2.3e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAG07572.1 - 0.0052 16.6 0.2 0.099 12.5 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 AAG07572.1 - 0.086 12.7 0.1 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AAG07572.1 - 0.14 11.8 0.4 0.36 10.4 0.0 2.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DAO PF01266.24 AAG07573.1 - 6.6e-37 127.9 0.9 7.7e-37 127.7 0.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG07573.1 - 0.00021 21.5 0.3 0.0015 18.7 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG07573.1 - 0.0011 18.3 0.0 0.013 14.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG07573.1 - 0.0027 17.0 0.1 0.0042 16.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 AAG07573.1 - 0.0066 16.4 0.2 0.028 14.4 0.2 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 AAG07573.1 - 0.23 10.3 0.3 0.33 9.8 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Sugar_tr PF00083.24 AAG07574.1 - 5.5e-52 177.1 19.7 7.1e-52 176.8 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAG07574.1 - 1.6e-39 135.8 71.2 1e-33 116.7 42.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM208_SND2 PF05620.11 AAG07574.1 - 0.08 12.7 4.0 1.4 8.7 3.0 2.9 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 MFS_1_like PF12832.7 AAG07574.1 - 6.2 5.6 22.4 1.6 7.5 5.3 2.5 2 1 0 2 2 2 0 MFS_1 like family DHDPS PF00701.22 AAG07575.1 - 1.2e-55 188.3 0.0 1.3e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldedh PF00171.22 AAG07576.1 - 3.4e-166 553.3 0.0 3.9e-166 553.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 AAG07577.1 - 9.4e-35 120.5 0.0 1.2e-34 120.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 AAG07577.1 - 6.1e-12 45.2 0.0 8.7e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 AAG07577.1 - 2e-07 30.3 0.2 0.11 11.3 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase Lycopene_cycl PF05834.12 AAG07577.1 - 2.3e-05 23.6 3.3 0.00091 18.4 3.3 2.7 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAG07577.1 - 0.0011 19.1 0.6 0.0035 17.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG07577.1 - 0.0062 15.8 2.5 0.19 10.9 0.5 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAG07577.1 - 0.02 14.5 5.0 0.094 12.3 2.1 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAG07577.1 - 0.026 13.9 3.0 0.31 10.3 3.0 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG07577.1 - 0.033 13.3 0.7 0.076 12.1 0.7 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 AAG07577.1 - 0.093 13.3 1.0 27 5.4 0.5 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AAG07577.1 - 0.094 12.4 0.6 0.22 11.2 0.6 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 AAG07577.1 - 0.15 10.7 0.1 0.46 9.1 0.1 1.7 1 1 0 1 1 1 0 HI0933-like protein DIOX_N PF14226.6 AAG07578.1 - 2.9e-31 108.7 0.0 4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 AAG07578.1 - 1.5e-23 83.2 0.0 2.7e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 AAG07579.1 - 1.1e-34 119.9 0.0 1.4e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07579.1 - 3.4e-11 43.5 0.0 7.7e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG07579.1 - 1.2e-07 31.5 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG07579.1 - 1.4e-05 25.5 0.1 2.2e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAG07579.1 - 5.9e-05 23.4 0.1 0.00012 22.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAG07579.1 - 0.00017 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 AAG07579.1 - 0.00021 21.4 0.1 0.00063 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAG07579.1 - 0.00031 19.7 0.3 0.6 8.8 0.1 3.0 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 AAG07579.1 - 0.00032 20.4 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 AAG07579.1 - 0.00075 20.1 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAG07579.1 - 0.0027 17.7 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 AAG07579.1 - 0.0054 16.5 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 AAG07579.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AAG07579.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 AAG07579.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AAG07579.1 - 0.047 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAG07579.1 - 0.047 14.2 0.3 0.073 13.6 0.0 1.4 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 AAG07579.1 - 0.049 13.2 0.1 0.14 11.7 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAG07579.1 - 0.052 13.8 0.3 0.14 12.4 0.1 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 AAG07579.1 - 0.059 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.18 AAG07579.1 - 0.061 12.6 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 AAG07579.1 - 0.066 13.0 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 AAG07579.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 AAG07579.1 - 0.081 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.18 AAG07579.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 AAG07579.1 - 0.13 11.0 0.3 0.26 10.1 0.0 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 AAG07579.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 AAG07579.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.20 AAG07579.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Herpes_Helicase PF02689.14 AAG07579.1 - 0.14 10.1 0.0 0.25 9.2 0.0 1.4 2 0 0 2 2 2 0 Helicase MMR_HSR1 PF01926.23 AAG07579.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA12 PF10443.9 AAG07579.1 - 0.15 10.7 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein PRK PF00485.18 AAG07579.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.18 AAG07579.1 - 0.19 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase BPD_transp_1 PF00528.22 AAG07580.1 - 3.2e-18 66.1 14.1 3.2e-18 66.1 14.1 1.4 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG07581.1 - 6.1e-17 62.0 11.7 8.5e-17 61.5 11.7 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 AAG07582.1 - 2.3e-50 171.1 0.1 2.7e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG07582.1 - 2.3e-05 24.6 0.0 0.00026 21.2 0.0 2.1 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAG07582.1 - 0.02 14.8 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like Response_reg PF00072.24 AAG07583.1 - 1e-23 83.6 0.0 1.7e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG07583.1 - 2.8e-15 55.6 0.0 3.9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG07583.1 - 5.5e-08 32.4 0.2 9.7e-08 31.6 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG07583.1 - 0.0002 20.8 0.4 0.00042 19.8 0.4 1.6 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG07583.1 - 0.00067 19.4 0.1 0.0015 18.3 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AAG07583.1 - 0.00075 19.4 0.2 0.0011 18.8 0.2 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_50 PF18024.1 AAG07583.1 - 0.073 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 AAG07583.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 AAG07583.1 - 0.15 12.2 1.2 0.31 11.2 0.0 2.2 2 1 1 3 3 3 0 Helix-turn-helix domain PAS_3 PF08447.12 AAG07584.1 - 1.6e-17 63.6 0.0 2.4e-15 56.6 0.1 3.1 3 0 0 3 3 3 1 PAS fold HATPase_c PF02518.26 AAG07584.1 - 1.4e-14 54.6 0.0 2.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAG07584.1 - 6.2e-14 52.2 11.1 3.3e-08 33.7 1.0 3.9 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 AAG07584.1 - 9e-13 48.2 0.0 5.2e-06 26.4 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAG07584.1 - 1.9e-10 40.9 0.0 1.3e-07 31.8 0.0 3.3 3 0 0 3 3 3 1 PAS domain HisKA PF00512.25 AAG07584.1 - 5.5e-09 35.9 0.1 2.5e-08 33.8 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 AAG07584.1 - 2e-07 31.1 0.0 9e-07 29.0 0.0 2.0 1 1 1 2 2 2 1 PAS domain PAS_8 PF13188.7 AAG07584.1 - 4e-05 23.5 0.2 0.48 10.5 0.0 3.7 3 0 0 3 3 3 2 PAS domain HATPase_c_2 PF13581.6 AAG07584.1 - 0.018 15.0 0.2 0.55 10.2 0.0 2.8 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAG07584.1 - 0.039 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Sigma54_DBD PF04552.13 AAG07584.1 - 0.17 11.5 0.3 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Sigma-54, DNA binding domain AMP-binding PF00501.28 AAG07585.1 - 1.7e-94 316.8 0.0 2e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG07585.1 - 1.7e-21 77.0 0.1 5.2e-21 75.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_C PF12806.7 AAG07586.1 - 1.8e-35 121.8 2.3 4.1e-35 120.6 2.3 1.6 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAG07586.1 - 3.2e-21 76.1 6.0 3.3e-21 76.1 1.4 2.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG07586.1 - 1e-17 64.1 0.0 2.4e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_DH_N PF12418.8 AAG07586.1 - 1.6e-11 44.0 0.8 3.9e-11 42.8 0.8 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_N PF02771.16 AAG07586.1 - 1.6e-11 44.8 1.0 4.4e-11 43.4 0.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAG07586.1 - 0.0034 17.7 1.6 0.026 14.8 0.3 2.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Lactamase_B PF00753.27 AAG07587.1 - 1.6e-26 93.6 2.7 2e-26 93.2 2.7 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG07587.1 - 2.6e-05 23.8 0.2 4.4e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Dala_Dala_lig_C PF07478.13 AAG07588.1 - 1.7e-51 174.6 0.0 2.4e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AAG07588.1 - 4.4e-22 78.5 0.0 8.3e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus CPSase_L_D2 PF02786.17 AAG07588.1 - 1.7e-09 37.5 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AAG07588.1 - 6.8e-07 29.0 0.0 1.5e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAG07588.1 - 0.00023 20.8 0.0 0.0026 17.4 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAG07588.1 - 0.0022 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp GARS_A PF01071.19 AAG07588.1 - 0.0033 17.2 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 AAG07588.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 AAG07588.1 - 0.15 11.8 0.0 0.84 9.4 0.0 2.2 2 1 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon NMO PF03060.15 AAG07589.1 - 8.4e-81 271.9 0.1 9.5e-81 271.7 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 AAG07589.1 - 8e-10 38.2 0.0 0.00063 18.8 1.4 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 AAG07589.1 - 0.00071 18.9 0.3 0.00099 18.4 0.3 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 AAG07589.1 - 0.00088 18.4 6.0 0.0015 17.6 6.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AAG07589.1 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Glyco_transf_4 PF13439.6 AAG07589.1 - 0.017 15.1 0.2 1.5 8.8 0.0 2.4 1 1 1 2 2 2 0 Glycosyltransferase Family 4 ThiG PF05690.14 AAG07589.1 - 0.029 13.7 7.3 0.074 12.3 6.5 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 AAG07589.1 - 0.054 12.8 0.5 0.36 10.1 1.1 2.0 2 1 0 2 2 2 0 Thiamine monophosphate synthase DUF561 PF04481.12 AAG07589.1 - 0.076 12.2 0.2 0.18 10.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF561) ADH_zinc_N PF00107.26 AAG07589.1 - 0.14 12.1 2.0 0.42 10.6 1.9 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Glu_synthase PF01645.17 AAG07589.1 - 2 7.4 4.8 3.8 6.5 4.8 1.4 1 1 0 1 1 1 0 Conserved region in glutamate synthase LysR_substrate PF03466.20 AAG07590.1 - 1.7e-36 125.6 4.7 2.3e-36 125.1 4.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG07590.1 - 2.9e-19 68.8 2.4 9.3e-19 67.1 2.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAG07590.1 - 0.0073 16.4 1.2 0.022 14.8 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_30 PF13556.6 AAG07590.1 - 0.076 12.8 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Lactonase PF10282.9 AAG07591.1 - 2.5e-113 378.9 0.1 2.9e-113 378.6 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 AAG07591.1 - 0.024 15.5 0.1 1.2 10.1 0.1 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DoxX PF07681.12 AAG07592.1 - 1.7e-15 57.4 10.6 2.8e-15 56.6 10.6 1.4 1 0 0 1 1 1 1 DoxX DoxX_2 PF13564.6 AAG07592.1 - 4.8e-05 23.4 10.2 4.8e-05 23.4 10.2 1.5 1 1 1 2 2 2 1 DoxX-like family SURF4 PF02077.15 AAG07592.1 - 0.00013 21.7 3.0 0.0014 18.3 3.2 1.9 1 1 1 2 2 2 2 SURF4 family DUF5056 PF16479.5 AAG07592.1 - 0.42 10.9 2.3 12 6.2 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5056) DUF2070 PF09843.9 AAG07592.1 - 2.2 6.5 5.7 2.7 6.2 5.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4231 PF14015.6 AAG07592.1 - 9.1 6.8 9.4 5.6 7.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) HlyD_D23 PF16576.5 AAG07593.1 - 1.5e-24 86.5 3.3 1.9e-24 86.1 0.7 1.9 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG07593.1 - 4.1e-15 56.4 0.2 4.8e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG07593.1 - 4.1e-09 36.1 4.8 1.9e-08 34.0 4.8 2.2 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG07593.1 - 0.00085 19.1 0.1 0.0026 17.5 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD PF00529.20 AAG07593.1 - 0.036 13.9 6.0 0.13 12.2 2.2 2.8 2 1 0 2 2 2 0 HlyD membrane-fusion protein of T1SS MlaD PF02470.20 AAG07593.1 - 0.14 12.5 0.2 1.9 8.8 0.1 2.5 2 0 0 2 2 2 0 MlaD protein ACR_tran PF00873.19 AAG07594.1 - 3.1e-269 895.9 13.4 3.5e-269 895.7 13.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG07594.1 - 1.1e-14 54.1 35.7 3.1e-07 29.6 11.5 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAG07594.1 - 0.00038 19.9 27.2 0.019 14.4 8.2 2.6 2 0 0 2 2 2 2 Protein export membrane protein OEP PF02321.18 AAG07595.1 - 7.7e-48 162.8 28.2 2e-26 93.0 10.7 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein DUF3209 PF11483.8 AAG07595.1 - 0.099 13.1 0.1 0.3 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Methyltransf_2 PF00891.18 AAG07596.1 - 5.9e-29 100.9 0.0 7.4e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 AAG07596.1 - 7.9e-07 29.0 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.14 AAG07596.1 - 0.019 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 AAG07596.1 - 0.075 13.7 0.1 0.33 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltrans_Mon PF14314.6 AAG07596.1 - 0.3 9.1 0.0 0.42 8.6 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase PHZA_PHZB PF03284.13 AAG07597.1 - 1.4e-85 284.6 0.2 1.6e-85 284.4 0.2 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B SnoaL_2 PF12680.7 AAG07597.1 - 4.2e-08 33.7 0.1 5.6e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAG07597.1 - 0.0006 19.6 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PikAIV_N PF18605.1 AAG07597.1 - 0.08 12.5 0.7 0.71 9.5 0.2 2.4 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PHZA_PHZB PF03284.13 AAG07598.1 - 7e-90 298.6 0.3 8.5e-90 298.3 0.3 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B SnoaL_2 PF12680.7 AAG07598.1 - 1.1e-05 25.9 0.0 1.8e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAG07598.1 - 0.0016 18.2 0.0 0.0052 16.6 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Adeno_GP19K PF04881.13 AAG07598.1 - 0.043 13.8 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus GP19K DAHP_synth_2 PF01474.16 AAG07599.1 - 2.7e-127 424.9 0.0 6.4e-78 262.2 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family Isochorismatase PF00857.20 AAG07600.1 - 3.2e-35 121.9 0.0 3.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Chorismate_bind PF00425.18 AAG07601.1 - 4.4e-47 160.8 0.0 5.9e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 AAG07601.1 - 1.2e-25 90.4 0.0 1.7e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PhzC-PhzF PF02567.16 AAG07602.1 - 2.8e-85 286.2 0.0 3.2e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Putative_PNPOx PF01243.20 AAG07604.1 - 9e-18 64.3 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 AAG07604.1 - 5.9e-10 39.1 0.3 1.6e-09 37.7 0.3 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 AAG07604.1 - 3.7e-05 24.3 0.0 6.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ABATE PF07336.11 AAG07604.1 - 0.1 13.3 4.0 0.14 12.8 0.6 2.2 2 0 0 2 2 2 0 Putative stress-induced transcription regulator FAD_binding_3 PF01494.19 AAG07605.1 - 1.6e-24 86.8 1.5 4.7e-13 49.1 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 AAG07605.1 - 1.8e-05 24.0 0.5 4.5e-05 22.7 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAG07605.1 - 5.8e-05 22.8 6.9 9.5e-05 22.1 0.7 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG07605.1 - 0.00012 22.3 0.8 0.00033 20.8 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AAG07605.1 - 0.00032 19.7 0.5 0.0031 16.4 0.4 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 AAG07605.1 - 0.0018 17.6 0.1 0.0033 16.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG07605.1 - 0.017 15.7 0.1 0.017 15.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG07605.1 - 0.034 13.4 0.4 0.09 12.0 0.8 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAG07605.1 - 0.077 12.3 0.1 0.17 11.1 0.1 1.6 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 AAG07605.1 - 0.11 11.8 0.3 0.18 11.0 0.3 1.2 1 0 0 1 1 1 0 Thi4 family Acatn PF13000.7 AAG07606.1 - 9.2e-21 73.9 10.4 2.5e-19 69.2 1.0 2.5 2 1 1 3 3 3 2 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.16 AAG07606.1 - 9.5e-18 64.2 42.1 9.5e-18 64.2 42.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 AAG07606.1 - 0.00037 18.8 5.3 0.00037 18.8 5.3 2.1 2 0 0 2 2 2 1 BT1 family DUF2070 PF09843.9 AAG07606.1 - 0.39 9.0 9.5 0.11 10.7 1.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) PepSY_TM PF03929.16 AAG07607.1 - 6.2e-29 101.6 9.8 6.2e-29 101.6 9.8 2.5 3 1 1 4 4 4 1 PepSY-associated TM region MatC_N PF07158.11 AAG07607.1 - 0.0021 18.1 5.5 1.6 8.8 0.1 3.3 3 0 0 3 3 3 3 Dicarboxylate carrier protein MatC N-terminus TonB_dep_Rec PF00593.24 AAG07609.1 - 4.9e-53 181.7 47.3 6.1e-53 181.3 38.6 2.0 1 1 1 2 2 2 2 TonB dependent receptor Plug PF07715.15 AAG07609.1 - 4.5e-12 46.5 0.1 1.2e-11 45.1 0.0 1.9 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl PF13505.6 AAG07609.1 - 0.00027 21.1 2.5 0.00027 21.1 2.5 2.8 2 1 1 3 3 3 1 Outer membrane protein beta-barrel domain ABC_tran PF00005.27 AAG07610.1 - 8.9e-27 94.3 0.0 1.3e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07610.1 - 5e-09 36.4 0.7 0.00033 20.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG07610.1 - 6e-07 29.1 0.0 0.00081 18.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAG07610.1 - 0.0012 18.7 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAG07610.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG07610.1 - 0.022 15.3 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAG07610.1 - 0.03 14.0 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG07610.1 - 0.086 13.1 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG07610.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 AAG07610.1 - 0.18 11.4 0.2 0.49 10.0 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_membrane PF00664.23 AAG07610.1 - 0.2 11.3 0.0 0.39 10.3 0.0 1.4 2 0 0 2 2 2 0 ABC transporter transmembrane region AAA_28 PF13521.6 AAG07610.1 - 2.3 8.4 8.4 15 5.8 0.1 3.3 2 2 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AAG07610.1 - 6.2 7.2 16.3 0.057 13.8 3.0 3.0 2 2 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 AAG07611.1 - 7.1e-25 88.1 0.0 1.1e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAG07611.1 - 3.1e-09 36.9 0.6 4.5e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 AAG07611.1 - 1.1e-08 35.2 0.0 0.00076 19.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG07611.1 - 9.6e-07 28.5 0.0 0.0012 18.4 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAG07611.1 - 2.8e-05 23.9 0.0 7.4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG07611.1 - 0.00015 22.2 1.1 0.00015 22.2 1.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG07611.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAG07611.1 - 0.001 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG07611.1 - 0.0028 17.9 0.1 0.014 15.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAG07611.1 - 0.0035 17.9 0.0 0.0071 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAG07611.1 - 0.008 16.3 1.0 0.026 14.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 AAG07611.1 - 0.0087 15.7 0.0 0.031 13.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAG07611.1 - 0.02 14.8 0.4 0.077 12.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 AAG07611.1 - 0.028 13.7 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 AAG07611.1 - 0.03 14.8 0.0 0.046 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAG07611.1 - 0.049 13.6 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 AAG07611.1 - 0.049 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAG07611.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 AAG07611.1 - 0.066 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase KAP_NTPase PF07693.14 AAG07611.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.23 AAG07611.1 - 0.13 12.3 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 AAG07611.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 AAG07611.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 AAG07611.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 AAG07611.1 - 0.22 11.9 0.0 0.35 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.22 AAG07611.1 - 0.23 11.0 0.1 0.55 9.8 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GFO_IDH_MocA PF01408.22 AAG07612.1 - 2.6e-14 54.0 0.0 5.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AMP-binding PF00501.28 AAG07613.1 - 2.1e-91 306.6 0.0 3.2e-91 306.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AAG07613.1 - 3.6e-24 85.3 0.0 5.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain TubC_N PF18563.1 AAG07613.1 - 8.9e-11 41.6 0.1 3e-10 39.9 0.1 1.9 1 0 0 1 1 1 1 TubC N-terminal docking domain Methyltransf_12 PF08242.12 AAG07613.1 - 2.4e-10 41.0 0.0 1.9e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 AAG07613.1 - 5.9e-08 32.9 0.0 2.9e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAG07613.1 - 6.2e-08 33.5 0.6 0.0094 16.9 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 AAG07613.1 - 1.6e-07 31.7 0.0 2.1e-06 28.0 0.0 2.5 1 1 0 1 1 1 1 Thioesterase domain Methyltransf_23 PF13489.6 AAG07613.1 - 5.4e-05 23.1 0.1 0.00026 20.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG07613.1 - 7.3e-05 23.4 0.0 0.00037 21.1 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG07613.1 - 0.0003 21.4 0.0 0.011 16.3 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG07613.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3726 PF12525.8 AAG07613.1 - 0.022 14.9 1.1 0.065 13.4 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) ACP_syn_III PF08545.10 AAG07613.1 - 0.028 14.3 0.0 0.09 12.6 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HTH_20 PF12840.7 AAG07613.1 - 0.11 12.5 4.2 0.13 12.3 0.4 3.3 2 0 0 2 2 2 0 Helix-turn-helix domain AMP-binding PF00501.28 AAG07614.1 - 3.5e-85 286.1 0.0 6.2e-85 285.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AAG07614.1 - 2.1e-29 102.5 0.0 3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 AAG07614.1 - 4.1e-26 91.1 0.2 6.2e-15 55.3 0.0 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAG07614.1 - 0.0073 17.3 0.1 0.37 11.8 0.0 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_12 PF08242.12 AAG07614.1 - 0.011 16.4 0.0 0.049 14.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 AAG07614.1 - 0.026 15.1 0.0 0.28 11.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 AAG07614.1 - 0.048 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HTH_18 PF12833.7 AAG07615.1 - 1.3e-21 76.6 1.3 1.4e-21 76.6 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07615.1 - 1.5e-11 44.1 0.0 9.6e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family GSH_synthase PF03199.15 AAG07615.1 - 0.077 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic glutathione synthase AMP-binding PF00501.28 AAG07616.1 - 6.5e-85 285.3 0.0 8.3e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG07616.1 - 1.2e-15 58.2 0.5 3.9e-15 56.6 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 AAG07616.1 - 0.15 10.9 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Thioesterase PF00975.20 AAG07617.1 - 1.5e-60 205.2 0.3 1.7e-60 205.0 0.3 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AAG07617.1 - 6.7e-09 36.7 13.7 9.2e-09 36.2 13.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG07617.1 - 0.0036 16.6 0.0 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 AAG07617.1 - 0.0058 16.5 0.2 0.0086 15.9 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 AAG07617.1 - 0.015 15.2 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) TPP_enzyme_N PF02776.18 AAG07617.1 - 0.044 13.4 0.1 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CM_2 PF01817.21 AAG07618.1 - 3.2e-14 53.0 0.2 3.7e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Prefoldin_3 PF13758.6 AAG07618.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit Chorismate_bind PF00425.18 AAG07619.1 - 1.8e-73 247.3 0.0 2.2e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Se-cys_synth_N PF12390.8 AAG07619.1 - 0.07 13.4 4.9 6.7 7.0 0.1 3.6 3 0 0 3 3 3 0 Selenocysteine synthase N terminal SSB PF00436.25 AAG07620.1 - 3.4e-43 145.9 0.9 4.1e-43 145.7 0.9 1.1 1 0 0 1 1 1 1 Single-strand binding protein family MFS_1 PF07690.16 AAG07621.1 - 3.4e-55 187.4 73.7 4.3e-46 157.5 41.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG07621.1 - 7.3e-12 44.9 30.3 4.1e-10 39.1 12.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAG07621.1 - 9.3e-05 21.4 22.9 0.012 14.5 12.7 2.8 1 1 1 2 2 2 2 MFS_1 like family PUCC PF03209.15 AAG07621.1 - 0.00088 18.4 37.3 0.0016 17.6 4.6 3.4 2 1 1 3 3 3 3 PUCC protein MtrF PF09472.10 AAG07621.1 - 0.012 14.9 0.7 0.012 14.9 0.7 3.6 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Spore_YhcN_YlaJ PF09580.10 AAG07621.1 - 0.11 12.6 1.2 0.16 12.1 1.2 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) UvrA_inter PF17760.1 AAG07622.1 - 7.5e-40 135.4 0.1 1.8e-39 134.2 0.1 1.7 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AAG07622.1 - 2.9e-33 114.5 0.0 5.1e-32 110.5 0.0 2.6 2 0 0 2 2 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 AAG07622.1 - 8.8e-22 78.1 0.0 0.00013 22.5 0.0 4.5 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.19 AAG07622.1 - 6.3e-10 38.9 0.0 0.2 11.0 0.0 4.3 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG07622.1 - 3.9e-08 32.9 1.2 0.00086 19.0 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG07622.1 - 1.7e-07 31.8 0.1 0.027 14.8 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain BCA_ABC_TP_C PF12399.8 AAG07622.1 - 1.2e-06 28.3 0.7 0.003 17.5 0.0 2.6 2 0 0 2 2 2 2 Branched-chain amino acid ATP-binding cassette transporter DnaJ_CXXCXGXG PF00684.19 AAG07622.1 - 9e-06 26.0 2.7 0.039 14.3 0.2 3.5 3 0 0 3 3 3 1 DnaJ central domain AAA_23 PF13476.6 AAG07622.1 - 1.2e-05 25.9 2.8 0.053 14.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AAG07622.1 - 2.5e-05 24.2 0.1 0.11 12.4 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 AAG07622.1 - 4.3e-05 23.8 0.5 0.74 10.1 0.2 3.1 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 AAG07622.1 - 6.4e-05 22.9 2.2 0.67 9.7 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 AAG07622.1 - 0.00019 22.0 0.2 2.3 8.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 AAG07622.1 - 0.00044 20.4 0.1 2.5 8.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 AAG07622.1 - 0.0018 18.0 0.4 1.6 8.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.20 AAG07622.1 - 0.0025 17.7 0.5 0.89 9.4 0.0 3.0 3 0 0 3 3 2 1 Adenylylsulphate kinase cobW PF02492.19 AAG07622.1 - 0.0044 16.6 1.9 0.27 10.8 0.7 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 AAG07622.1 - 0.0045 16.3 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 AAG07622.1 - 0.0046 16.7 0.0 0.26 11.0 0.1 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 AAG07622.1 - 0.006 16.3 0.2 8.6 6.0 0.1 3.5 3 0 0 3 3 3 0 AAA domain Zn-ribbon_8 PF09723.10 AAG07622.1 - 0.006 16.7 9.3 0.44 10.7 0.4 3.5 3 0 0 3 3 3 2 Zinc ribbon domain AAA_14 PF13173.6 AAG07622.1 - 0.009 16.0 0.1 8.8 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Anti-TRAP PF15777.5 AAG07622.1 - 0.011 15.7 3.9 4.5 7.3 0.3 3.7 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein AAA_25 PF13481.6 AAG07622.1 - 0.013 15.1 2.3 0.27 10.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 AAG07622.1 - 0.018 15.1 0.1 1.6 8.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase PF06745.13 AAG07622.1 - 0.026 13.9 0.1 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 AAG07622.1 - 0.032 14.2 0.1 6.3 6.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 AAG07622.1 - 0.1 12.5 2.2 2.6 7.9 0.1 3.5 4 0 0 4 4 4 0 NTPase ATPase_2 PF01637.18 AAG07622.1 - 0.11 12.4 0.0 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 AAG07622.1 - 0.11 12.7 0.7 22 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAG07622.1 - 0.15 11.0 2.3 9 5.3 0.2 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_7 PF12775.7 AAG07622.1 - 0.22 11.0 0.2 18 4.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Zn_Tnp_IS1595 PF12760.7 AAG07622.1 - 3.6 7.6 8.6 2.8 8.0 0.0 3.6 3 1 1 4 4 3 0 Transposase zinc-ribbon domain Ferritin PF00210.24 AAG07623.1 - 9e-38 129.4 1.6 1e-37 129.2 1.6 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AAG07623.1 - 0.018 15.4 0.7 0.11 12.9 0.8 1.9 1 1 0 1 1 1 0 Rubrerythrin Catalase PF00199.19 AAG07624.1 - 6.1e-187 621.4 2.2 7.3e-187 621.1 2.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AAG07624.1 - 5.7e-21 74.5 0.1 1.1e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribosomal_L17 PF01196.19 AAG07625.1 - 2.4e-33 114.9 0.0 2.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 RNA_pol_A_bac PF01000.26 AAG07626.1 - 2.4e-25 89.1 0.1 4.7e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_A_CTD PF03118.15 AAG07626.1 - 1.9e-24 85.2 0.3 3.5e-24 84.3 0.3 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 AAG07626.1 - 4.8e-24 83.6 0.0 9.9e-24 82.6 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 AAG07626.1 - 0.00093 18.9 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S4 PF00163.19 AAG07627.1 - 4.7e-34 117.1 3.5 7.8e-34 116.5 3.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AAG07627.1 - 7.9e-21 73.5 0.1 1.4e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.6 AAG07627.1 - 0.012 15.4 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Mut7-C ubiquitin S4_2 PF13275.6 AAG07627.1 - 0.019 14.8 0.1 0.019 14.8 0.1 1.7 2 0 0 2 2 2 0 S4 domain PCB_OB PF17092.5 AAG07627.1 - 0.02 15.6 0.2 0.039 14.7 0.2 1.4 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain TyrRSs_C PF16714.5 AAG07627.1 - 0.053 13.3 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain E1_dh PF00676.20 AAG07627.1 - 0.083 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component E1-E2_ATPase PF00122.20 AAG07627.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Ribosomal_S11 PF00411.19 AAG07628.1 - 2.1e-51 173.0 0.3 2.4e-51 172.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S13 PF00416.22 AAG07629.1 - 3.6e-35 121.2 5.8 3.3e-33 114.8 5.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AAG07629.1 - 0.00051 18.9 0.0 0.00054 18.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DNA_pol_lambd_f PF10391.9 AAG07629.1 - 0.014 15.2 0.1 0.038 13.8 0.1 1.9 1 1 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_6 PF14579.6 AAG07629.1 - 0.023 15.0 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix motif H2TH PF06831.14 AAG07629.1 - 0.055 13.5 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain HHH_3 PF12836.7 AAG07629.1 - 0.096 13.0 0.0 0.65 10.3 0.0 2.2 1 1 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.23 AAG07629.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ribosomal_L36 PF00444.18 AAG07630.1 - 6e-21 74.4 8.0 6.4e-21 74.3 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 SecY PF00344.20 AAG07631.1 - 3e-115 384.7 16.4 3.8e-115 384.3 16.4 1.1 1 0 0 1 1 1 1 SecY translocase Ribosomal_L27A PF00828.19 AAG07632.1 - 6e-28 98.1 2.8 8.2e-28 97.6 2.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L30 PF00327.20 AAG07633.1 - 1.2e-17 63.5 0.1 1.3e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5_C PF03719.15 AAG07634.1 - 3.7e-31 106.4 0.7 5.7e-31 105.8 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AAG07634.1 - 2.5e-27 94.7 3.8 2.5e-27 94.7 3.8 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_L18p PF00861.22 AAG07635.1 - 1e-42 145.1 4.3 1.2e-42 145.0 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast TGS PF02824.21 AAG07635.1 - 0.0056 16.7 0.4 0.0093 16.0 0.2 1.5 1 1 0 1 1 1 1 TGS domain Ribosomal_L6 PF00347.23 AAG07636.1 - 4.9e-38 129.7 0.1 8.6e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S8 PF00410.19 AAG07637.1 - 4.9e-50 168.7 0.0 5.5e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.21 AAG07638.1 - 8.7e-25 86.3 1.0 1.2e-24 85.8 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e SpoIIIAH PF12685.7 AAG07638.1 - 0.037 13.9 1.6 0.042 13.7 1.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Ribosomal_L5_C PF00673.21 AAG07639.1 - 8.9e-40 134.8 0.0 1.4e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AAG07639.1 - 5.1e-29 100.4 0.5 8.6e-29 99.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 TraC PF07820.12 AAG07639.1 - 0.027 14.8 0.2 0.045 14.1 0.2 1.3 1 0 0 1 1 1 0 TraC-like protein ribosomal_L24 PF17136.4 AAG07640.1 - 1.2e-25 89.7 0.6 1.9e-25 89.0 0.6 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 AAG07640.1 - 5e-06 26.3 3.0 5e-06 26.3 3.0 1.7 2 0 0 2 2 2 1 KOW motif Ribosomal_L14 PF00238.19 AAG07641.1 - 4.7e-55 184.9 1.4 5.1e-55 184.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.20 AAG07642.1 - 6.7e-34 115.8 1.1 9.3e-34 115.4 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Helicase_C_2 PF13307.6 AAG07642.1 - 0.09 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Helicase C-terminal domain Ribosomal_L29 PF00831.23 AAG07643.1 - 3.7e-23 81.2 2.9 4.1e-23 81.1 2.9 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.13 AAG07643.1 - 0.001 19.2 1.0 0.0013 18.8 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) YjcZ PF13990.6 AAG07643.1 - 0.041 13.3 0.4 0.037 13.4 0.4 1.0 1 0 0 1 1 1 0 YjcZ-like protein Ribosomal_L16 PF00252.18 AAG07644.1 - 1.7e-47 160.7 0.5 1.9e-47 160.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S3_C PF00189.20 AAG07645.1 - 1.8e-42 143.8 2.0 3.4e-42 142.9 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AAG07645.1 - 4.5e-22 77.7 1.2 4.5e-22 77.7 1.2 2.0 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 AAG07645.1 - 0.013 15.3 0.1 0.037 13.9 0.1 1.7 1 1 0 1 1 1 0 KH domain DNA_pol3_a_NI PF14480.6 AAG07645.1 - 0.074 13.1 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I Ribosomal_L22 PF00237.19 AAG07646.1 - 3.3e-34 117.2 1.6 3.7e-34 117.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.21 AAG07647.1 - 3.6e-35 119.7 0.1 4.1e-35 119.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L2_C PF03947.18 AAG07648.1 - 4.4e-56 188.5 3.6 7.8e-56 187.7 3.6 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AAG07648.1 - 7.6e-34 115.5 1.8 1.2e-32 111.7 1.4 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L23 PF00276.20 AAG07649.1 - 8.8e-31 106.1 0.1 1e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L4 PF00573.22 AAG07650.1 - 1e-63 214.5 0.3 1.2e-63 214.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.22 AAG07651.1 - 1.5e-16 60.3 7.5 3.5e-16 59.2 5.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_S10 PF00338.22 AAG07652.1 - 2.1e-35 120.9 0.2 2.3e-35 120.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GTP_EFTU PF00009.27 AAG07653.1 - 2.1e-57 193.8 0.0 2.8e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AAG07653.1 - 1.3e-33 115.6 0.0 2.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AAG07653.1 - 4.5e-16 59.0 5.9 1e-15 57.9 5.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAG07653.1 - 3.9e-05 23.7 0.0 8.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAG07653.1 - 0.098 12.6 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Lsm_C PF14894.6 AAG07653.1 - 0.44 10.3 2.3 1 9.2 2.3 1.5 1 0 0 1 1 1 0 Lsm C-terminal GTP_EFTU PF00009.27 AAG07654.1 - 5.6e-65 218.5 0.0 8.4e-65 218.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AAG07654.1 - 3.4e-42 143.0 0.3 6.4e-42 142.2 0.3 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AAG07654.1 - 7.9e-36 122.0 0.1 2.2e-35 120.6 0.1 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AAG07654.1 - 4e-31 106.9 0.1 1.3e-30 105.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAG07654.1 - 3.2e-18 65.9 0.6 8.2e-18 64.6 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AAG07654.1 - 4.7e-07 29.7 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 AAG07654.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_S7 PF00177.21 AAG07655.1 - 8e-67 223.5 3.7 8.9e-67 223.4 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 AAG07656.1 - 3.3e-42 142.7 0.6 3.8e-42 142.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 AAG07656.1 - 0.14 12.9 0.0 0.29 11.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12 RNA_pol_Rpb1_1 PF04997.12 AAG07657.1 - 1.5e-90 303.7 0.0 2.6e-90 302.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AAG07657.1 - 1.6e-77 260.5 0.0 2.8e-77 259.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AAG07657.1 - 8.9e-39 133.4 0.0 2.7e-28 99.3 0.0 2.8 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AAG07657.1 - 2.1e-30 105.7 0.0 5.7e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AAG07657.1 - 1.5e-20 73.1 0.5 3.4e-20 72.0 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M23 PF01551.22 AAG07657.1 - 0.0015 18.7 0.1 0.99 9.7 0.0 4.3 5 1 1 6 6 6 1 Peptidase family M23 Apocytochr_F_C PF01333.19 AAG07657.1 - 0.058 13.4 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Apocytochrome F, C-terminal ApbA_C PF08546.11 AAG07657.1 - 0.062 13.5 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF3150 PF11348.8 AAG07657.1 - 0.073 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Biotin_lipoyl_2 PF13533.6 AAG07657.1 - 0.15 11.9 2.1 59 3.6 0.0 4.2 3 1 1 4 4 4 0 Biotin-lipoyl like RNA_pol_Rpb2_6 PF00562.28 AAG07658.1 - 1.9e-161 537.5 0.1 3.2e-160 533.5 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AAG07658.1 - 3.8e-41 140.8 0.0 8.9e-41 139.6 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 AAG07658.1 - 9.8e-32 109.0 0.1 2.7e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 AAG07658.1 - 2.2e-27 95.2 0.1 4.7e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 AAG07658.1 - 4.5e-26 91.6 0.0 1.1e-14 54.5 0.0 2.7 3 0 0 3 3 3 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_45 PF10385.9 AAG07658.1 - 3.4e-21 75.3 0.4 4.9e-20 71.5 0.7 2.8 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain 7TMR-HDED PF07697.11 AAG07658.1 - 0.02 15.0 2.0 0.083 13.0 0.1 2.4 2 0 0 2 2 2 0 7TM-HD extracellular Ribosomal_L12 PF00542.19 AAG07659.1 - 3e-29 101.2 10.8 3e-29 101.2 10.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AAG07659.1 - 2.3e-17 62.4 10.4 2.3e-17 62.4 10.4 2.3 2 1 1 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Monooxygenase_B PF04744.12 AAG07659.1 - 0.11 11.3 0.5 0.12 11.2 0.5 1.0 1 0 0 1 1 1 0 Monooxygenase subunit B protein Ribosomal_60s PF00428.19 AAG07659.1 - 2.2 8.9 24.8 0.17 12.5 9.2 2.2 1 1 1 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 AAG07660.1 - 2e-26 92.1 0.4 2.8e-26 91.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L1 PF00687.21 AAG07661.1 - 2.5e-49 167.8 0.0 3.1e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Rotamase_2 PF13145.6 AAG07661.1 - 0.036 14.9 0.6 0.25 12.2 0.0 2.3 2 1 0 2 2 2 0 PPIC-type PPIASE domain Ribosomal_L11_N PF03946.14 AAG07662.1 - 1.2e-31 108.4 0.9 1.6e-31 107.9 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AAG07662.1 - 3.8e-25 88.2 1.0 6.1e-25 87.5 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NusG PF02357.19 AAG07663.1 - 2e-28 98.7 0.5 3e-28 98.2 0.1 1.5 2 0 0 2 2 2 1 Transcription termination factor nusG KOW PF00467.29 AAG07663.1 - 2.9e-09 36.5 0.1 5.4e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 KOW motif SecE PF00584.20 AAG07664.1 - 2.4e-20 72.2 3.6 2.4e-20 72.2 3.6 2.9 3 0 0 3 3 3 1 SecE/Sec61-gamma subunits of protein translocation complex VCPO_N PF17897.1 AAG07664.1 - 0.0077 16.1 0.0 0.0086 15.9 0.0 1.1 1 0 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain DUF1616 PF07760.11 AAG07664.1 - 0.02 14.3 4.3 0.025 14.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Ceramidase PF05875.12 AAG07664.1 - 0.045 13.2 1.7 0.054 12.9 1.7 1.1 1 0 0 1 1 1 0 Ceramidase DUF4271 PF14093.6 AAG07664.1 - 0.082 12.8 7.1 1.1 9.1 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) DUF4191 PF13829.6 AAG07664.1 - 1.9 7.8 14.8 0.25 10.6 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF983 PF06170.12 AAG07664.1 - 4.9 7.6 12.8 1.7 9.1 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF1198 PF06711.11 AAG07664.1 - 7.5 6.6 8.1 1.3 9.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1198) GTP_EFTU PF00009.27 AAG07665.1 - 2.1e-57 193.8 0.0 2.8e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AAG07665.1 - 1.3e-33 115.6 0.0 2.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AAG07665.1 - 4.5e-16 59.0 5.9 1e-15 57.9 5.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAG07665.1 - 3.9e-05 23.7 0.0 8.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAG07665.1 - 0.098 12.6 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Lsm_C PF14894.6 AAG07665.1 - 0.44 10.3 2.3 1 9.2 2.3 1.5 1 0 0 1 1 1 0 Lsm C-terminal SPOR PF05036.13 AAG07666.1 - 1.2e-12 48.0 0.2 1.8e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Sporulation related domain RraB PF06877.11 AAG07666.1 - 0.03 15.0 0.0 11 6.8 0.0 2.4 2 0 0 2 2 2 0 Regulator of ribonuclease activity B Pilus_CpaD PF09476.10 AAG07666.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Pan_kinase PF03309.14 AAG07667.1 - 1.3e-45 155.8 0.1 1.5e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Type III pantothenate kinase AzlD PF05437.12 AAG07667.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) BPL_LplA_LipB PF03099.19 AAG07668.1 - 2e-18 66.6 0.0 3.1e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 AAG07668.1 - 1.5e-09 37.6 0.1 6e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 HTH domain HTH_AsnC-type PF13404.6 AAG07668.1 - 5.6e-05 22.9 0.8 0.00014 21.6 0.0 2.2 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAG07668.1 - 0.00031 20.2 0.0 0.00085 18.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding BPL_LplA_LipB_2 PF16917.5 AAG07668.1 - 0.00057 19.5 0.0 0.00087 18.9 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_1 PF00126.27 AAG07668.1 - 0.0021 18.0 0.4 0.0085 16.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family BPL_C PF02237.17 AAG07668.1 - 0.004 17.0 0.5 0.011 15.7 0.5 1.8 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain GntR PF00392.21 AAG07668.1 - 0.052 13.2 2.2 3.4 7.4 0.1 2.9 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family SbcD_C PF12320.8 AAG07669.1 - 9.3e-16 57.9 0.5 1.9e-15 56.9 0.5 1.5 1 0 0 1 1 1 1 Type 5 capsule protein repressor C-terminal domain Metallophos PF00149.28 AAG07669.1 - 1e-13 52.3 0.1 2.2e-13 51.2 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAG07669.1 - 1.4e-07 31.9 3.7 3.6e-06 27.3 3.7 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SbcCD_C PF13558.6 AAG07670.1 - 7.5e-13 48.5 0.2 2.6e-12 46.8 0.2 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 AAG07670.1 - 1.2e-10 41.2 0.9 1.3e-05 24.8 0.8 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG07670.1 - 5e-07 29.4 0.1 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG07670.1 - 2.1e-06 28.4 146.9 1.8e+04 -33.2 146.9 7.8 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 AAG07670.1 - 4.1e-06 26.8 5.3 0.00099 19.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AAG07670.1 - 0.021 15.4 0.1 0.021 15.4 0.1 6.3 3 3 0 3 3 3 0 ABC transporter AAA_22 PF13401.6 AAG07670.1 - 0.079 13.2 0.0 0.079 13.2 0.0 6.0 2 1 2 5 5 5 0 AAA domain MMR_HSR1 PF01926.23 AAG07670.1 - 0.11 12.6 0.0 0.51 10.4 0.0 2.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 AAG07670.1 - 0.12 12.9 2.3 0.95 10.0 0.0 3.9 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AAG07670.1 - 0.15 11.7 0.0 0.15 11.7 0.0 3.2 2 2 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 AAG07671.1 - 3.9e-30 105.0 0.3 1.4e-29 103.2 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAG07671.1 - 2.4e-27 96.0 0.0 5.1e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAG07671.1 - 4.2e-15 55.3 0.1 8.8e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 AAG07671.1 - 7e-13 48.8 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_11 PF13086.6 AAG07671.1 - 5.2e-10 39.6 0.8 3.2e-05 23.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAG07671.1 - 6.1e-08 32.7 0.8 0.0036 17.1 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase SH3_13 PF18335.1 AAG07671.1 - 8.4e-07 28.7 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_22 PF13401.6 AAG07671.1 - 1.6e-05 25.2 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAG07671.1 - 0.014 15.9 0.0 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 AAG07671.1 - 0.018 14.6 0.0 0.04 13.4 0.0 1.4 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 AAG07671.1 - 0.019 15.4 1.0 0.019 15.4 1.0 3.2 3 1 1 4 4 4 0 AAA ATPase domain AAA_28 PF13521.6 AAG07671.1 - 0.046 14.0 0.3 0.12 12.7 0.3 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AAG07671.1 - 0.072 12.3 0.0 0.15 11.3 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 AAG07671.1 - 0.076 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 AAG07671.1 - 0.081 12.4 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.15 AAG07671.1 - 0.1 12.5 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 AAG07671.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 AAG07671.1 - 0.16 11.5 1.4 0.68 9.5 0.9 2.3 1 1 1 2 2 2 0 AAA domain UvrD-helicase PF00580.21 AAG07672.1 - 1.5e-58 198.8 0.0 1.3e-57 195.8 0.0 2.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AAG07672.1 - 3.1e-22 79.4 0.0 2.1e-12 47.1 0.0 3.1 2 1 0 3 3 3 3 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AAG07672.1 - 1e-17 64.9 0.0 4.6e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAG07672.1 - 2.3e-10 40.1 0.1 0.00044 20.0 0.3 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 AAG07672.1 - 1.6e-07 31.6 0.3 1.3e-06 28.6 0.1 2.6 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.6 AAG07672.1 - 0.0019 17.9 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAG07672.1 - 0.0046 17.2 0.0 3.6 7.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 AAG07672.1 - 0.022 14.4 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AAG07672.1 - 0.043 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Exonuc_V_gamma PF04257.14 AAG07673.1 - 1.4e-286 952.8 0.0 1.7e-286 952.5 0.0 1.1 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RecC_C PF17946.1 AAG07673.1 - 1e-49 169.1 13.9 1e-49 169.1 13.9 3.2 4 0 0 4 4 4 1 RecC C-terminal domain BPL_LplA_LipB PF03099.19 AAG07674.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family EamA PF00892.20 AAG07675.1 - 3.7e-40 137.3 42.4 2.3e-20 73.1 18.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 AAG07675.1 - 0.002 17.1 9.1 0.002 17.1 9.1 2.1 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like HTH_18 PF12833.7 AAG07676.1 - 7.5e-23 80.6 0.8 1.6e-22 79.6 0.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07676.1 - 2e-12 46.9 0.2 5.1e-05 23.3 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAG07676.1 - 3e-11 43.4 0.1 7.1e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAG07676.1 - 0.00058 19.5 0.1 0.00097 18.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Chromate_transp PF02417.15 AAG07677.1 - 1.1e-73 246.6 35.3 8.3e-41 139.7 10.7 2.5 3 0 0 3 3 3 2 Chromate transporter TMEM125 PF15109.6 AAG07677.1 - 0.19 12.1 4.9 6.3 7.2 1.4 2.7 3 0 0 3 3 3 0 TMEM125 protein family MCPsignal PF00015.21 AAG07678.1 - 1.1e-40 139.3 17.4 1.1e-40 139.3 17.4 2.4 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.12 AAG07678.1 - 0.0007 19.6 1.0 0.0007 19.6 1.0 3.3 2 1 1 3 3 3 1 Laminin Domain II DUF677 PF05055.12 AAG07678.1 - 0.0047 15.9 2.2 0.019 13.9 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF677) BLOC1_2 PF10046.9 AAG07678.1 - 0.0096 16.2 8.8 3.7 7.9 0.3 3.8 3 1 1 4 4 4 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 AAG07678.1 - 0.013 15.5 0.9 0.013 15.5 0.9 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Sec2p PF06428.11 AAG07678.1 - 0.051 13.6 2.8 0.13 12.2 0.1 2.8 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p DUF948 PF06103.11 AAG07678.1 - 0.16 12.2 8.2 2.9 8.2 3.3 4.1 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) DASH_Hsk3 PF08227.11 AAG07678.1 - 0.22 11.9 2.3 0.57 10.6 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like EzrA PF06160.12 AAG07678.1 - 0.27 9.4 5.3 0.23 9.6 0.2 2.5 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Sec34 PF04136.15 AAG07678.1 - 1.1 9.1 3.3 7.9 6.4 0.3 3.1 3 0 0 3 3 3 0 Sec34-like family ApoLp-III PF07464.11 AAG07678.1 - 1.2 9.2 7.1 0.76 9.9 2.1 2.8 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Shikimate_DH PF01488.20 AAG07678.1 - 1.3 9.0 4.3 1.7 8.7 0.2 2.9 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Baculo_PEP_C PF04513.12 AAG07678.1 - 2.5 8.1 11.9 0.28 11.2 1.8 3.4 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.11 AAG07678.1 - 3.2 7.8 8.3 3.8 7.6 0.8 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1515) UPF0242 PF06785.11 AAG07678.1 - 4 7.5 6.4 9.6 6.3 0.6 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 AAG07678.1 - 4.2 7.1 10.8 8.7 6.1 0.2 3.6 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH Mod_r PF07200.13 AAG07678.1 - 4.7 7.3 10.3 6.2 6.9 3.9 2.9 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 AAG07678.1 - 6.7 6.0 8.0 2.6 7.3 1.7 2.8 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding PHO4 PF01384.20 AAG07680.1 - 1.7e-88 296.9 8.5 2.3e-88 296.5 8.5 1.2 1 0 0 1 1 1 1 Phosphate transporter family Flavi_M PF01004.19 AAG07680.1 - 0.039 13.7 0.7 13 5.6 0.0 2.8 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M HATPase_c PF02518.26 AAG07681.1 - 2.4e-18 66.7 0.0 4.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAG07681.1 - 1.4e-14 54.1 0.0 1.1e-08 35.3 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 AAG07681.1 - 1.3e-12 47.9 6.1 1.2e-08 35.2 0.3 3.8 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AAG07681.1 - 1.7e-08 34.5 0.0 0.00038 20.4 0.0 3.6 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 AAG07681.1 - 6.2e-07 29.3 0.2 0.017 15.1 0.0 3.0 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 AAG07681.1 - 1.2e-05 25.2 0.1 1.2e-05 25.2 0.1 3.2 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAG07681.1 - 1.7e-05 25.0 0.0 0.7 10.2 0.0 3.5 3 0 0 3 3 3 2 PAS domain TadE PF07811.12 AAG07682.1 - 5.5e-06 26.6 4.5 5.5e-06 26.6 4.5 1.6 2 0 0 2 2 2 1 TadE-like protein TadF PF16964.5 AAG07682.1 - 0.16 11.7 0.2 0.22 11.3 0.2 1.2 1 0 0 1 1 1 0 Putative tight adherence pilin protein F Peptidase_A24 PF01478.18 AAG07683.1 - 3.4e-09 37.1 10.2 5.4e-09 36.4 10.2 1.3 1 0 0 1 1 1 1 Type IV leader peptidase family DUF2070 PF09843.9 AAG07683.1 - 0.074 11.3 2.0 0.091 11.0 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MerC PF03203.14 AAG07683.1 - 0.17 12.3 5.9 0.34 11.4 1.1 2.4 1 1 1 2 2 2 0 MerC mercury resistance protein DUF1201 PF06716.11 AAG07683.1 - 2.9 8.0 6.7 0.44 10.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Response_reg PF00072.24 AAG07684.1 - 3.2e-19 69.1 0.0 4.9e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAG07684.1 - 2.1e-15 56.0 0.1 3.6e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAG07684.1 - 0.00011 21.9 0.2 0.00039 20.0 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG07684.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_4 PF13613.6 AAG07684.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.16 AAG07684.1 - 0.039 13.5 0.5 0.28 10.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.15 AAG07684.1 - 0.054 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase TIP120 PF08623.10 AAG07684.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Tad_C PF09977.9 AAG07685.1 - 3.6e-09 37.7 11.9 2e-08 35.4 6.8 2.7 2 0 0 2 2 2 1 Putative Tad-like Flp pilus-assembly Tad PF13400.6 AAG07685.1 - 4.9e-08 33.2 4.8 4.9e-08 33.2 4.8 2.8 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like DUF3613 PF12266.8 AAG07686.1 - 1.7e-30 104.6 6.7 2e-30 104.3 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3613) TPR_16 PF13432.6 AAG07687.1 - 1.8e-06 28.5 14.5 2.3e-05 24.9 2.1 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAG07687.1 - 8.1e-06 25.6 11.2 0.0035 17.3 0.0 4.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAG07687.1 - 1.8e-05 24.8 0.0 0.76 10.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 AAG07687.1 - 0.0015 18.9 21.1 1.2 9.9 0.2 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 AAG07687.1 - 0.0046 17.4 12.8 0.2 12.2 0.0 3.9 3 2 3 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAG07687.1 - 0.0064 16.2 3.0 0.6 9.9 0.0 3.3 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 AAG07687.1 - 0.0088 16.2 0.0 0.54 10.6 0.0 3.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 AAG07687.1 - 0.023 14.8 9.8 0.045 13.9 1.3 3.0 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAG07687.1 - 0.041 13.7 0.7 7.1 6.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAG07687.1 - 0.083 13.2 11.1 1 9.7 0.3 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAG07687.1 - 0.67 10.7 8.6 23 5.9 0.2 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAG07687.1 - 4.2 8.4 19.6 0.2 12.6 0.8 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAG07687.1 - 9.3 6.3 10.1 4.1 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat T2SSF PF00482.23 AAG07688.1 - 3.3e-15 56.2 2.3 3.3e-15 56.2 2.3 2.3 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F ATP1G1_PLM_MAT8 PF02038.16 AAG07688.1 - 0.12 11.8 0.2 2.9 7.4 0.1 2.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family T2SSF PF00482.23 AAG07689.1 - 1.8e-16 60.3 0.4 4.4e-16 59.0 0.4 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F T2SSE PF00437.20 AAG07690.1 - 3.6e-91 305.0 0.1 4.5e-91 304.7 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AAG07690.1 - 8.9e-05 22.9 0.1 0.00041 20.8 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 AAG07690.1 - 0.00018 22.0 0.0 0.00033 21.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 AAG07690.1 - 0.0078 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG07690.1 - 0.0085 15.8 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AAG07690.1 - 0.0097 16.3 0.1 0.029 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AAG07690.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 AAG07690.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 AAG07690.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 AAG07690.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 AAG07690.1 - 0.024 15.2 0.0 0.042 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAG07690.1 - 0.032 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIF1 PF05970.14 AAG07690.1 - 0.044 13.0 0.0 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase FtsK_SpoIIIE PF01580.18 AAG07690.1 - 0.048 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 AAG07690.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 AAG07690.1 - 0.095 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 AAG07690.1 - 0.1 12.9 1.5 0.61 10.4 0.2 2.7 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 AAG07690.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_2 PF07724.14 AAG07690.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TrwB_AAD_bind PF10412.9 AAG07690.1 - 0.15 10.9 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 AAG07690.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TadZ_N PF16968.5 AAG07691.1 - 2.1e-87 289.5 4.5 4.5e-87 288.5 4.5 1.6 1 0 0 1 1 1 1 Pilus assembly protein TadZ N-terminal DUF3487 PF11990.8 AAG07691.1 - 0.017 15.0 0.1 8 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Response_reg PF00072.24 AAG07691.1 - 0.044 14.0 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Response regulator receiver domain Secretin PF00263.21 AAG07692.1 - 1.5e-43 148.4 0.0 2e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein T2SS-T3SS_pil_N PF13629.6 AAG07692.1 - 1.3e-19 69.7 0.0 2.4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Pilus formation protein N terminal region RcpC PF16976.5 AAG07693.1 - 3.9e-30 104.3 0.0 6.5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB SAF PF08666.12 AAG07693.1 - 5.4e-08 33.3 0.1 1.2e-07 32.2 0.1 1.6 1 0 0 1 1 1 1 SAF domain ChapFlgA PF13144.6 AAG07693.1 - 0.06 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Flp_Fap PF04964.14 AAG07694.1 - 5.9e-16 58.0 1.8 7.5e-16 57.7 1.8 1.2 1 0 0 1 1 1 1 Flp/Fap pilin component DUF4244 PF14029.6 AAG07694.1 - 0.0011 18.4 0.5 0.0014 18.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4244) TPPK_C PF12555.8 AAG07694.1 - 0.0059 16.6 0.7 0.0083 16.2 0.7 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal MCPsignal PF00015.21 AAG07695.1 - 9.7e-45 152.5 33.8 2.1e-44 151.4 22.9 2.4 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAG07695.1 - 1.3e-35 123.4 5.9 1e-34 120.5 0.0 3.6 2 1 2 4 4 4 1 Cache domain HAMP PF00672.25 AAG07695.1 - 3.2e-15 56.2 3.8 6.5e-14 52.0 0.2 3.7 3 1 0 3 3 2 1 HAMP domain DUF948 PF06103.11 AAG07695.1 - 0.00019 21.6 23.6 0.027 14.7 2.0 5.5 2 1 1 4 4 4 2 Bacterial protein of unknown function (DUF948) dCache_2 PF08269.11 AAG07695.1 - 0.015 14.5 2.9 0.096 11.8 0.0 2.8 2 1 0 3 3 3 0 Cache domain Arfaptin PF06456.13 AAG07695.1 - 0.017 14.7 0.8 0.017 14.7 0.8 2.7 2 1 1 3 3 3 0 Arfaptin-like domain Phage_DsbA PF11126.8 AAG07695.1 - 0.13 12.5 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator DsbA BLOC1_2 PF10046.9 AAG07695.1 - 0.2 12.0 12.0 2 8.8 0.4 4.3 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 kleA_kleC PF17383.2 AAG07695.1 - 0.23 11.8 9.8 0.62 10.4 1.5 3.5 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A DUF3450 PF11932.8 AAG07695.1 - 0.68 9.2 20.8 0.15 11.3 6.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2408 PF10303.9 AAG07695.1 - 2.3 8.8 7.8 0.38 11.3 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) HisKA PF00512.25 AAG07695.1 - 2.6 8.2 5.7 5.8 7.0 0.6 4.0 3 1 1 4 4 4 0 His Kinase A (phospho-acceptor) domain Chlorosome_CsmC PF11098.8 AAG07695.1 - 4.7 7.2 10.3 2.2 8.3 0.0 3.8 1 1 2 4 4 4 0 Chlorosome envelope protein C Phage_Mu_Gam PF07352.12 AAG07695.1 - 5.8 6.8 8.8 46 3.9 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Tup_N PF08581.10 AAG07695.1 - 8.9 6.7 7.4 37 4.7 0.1 3.4 2 1 1 3 3 3 0 Tup N-terminal DUF853 PF05872.12 AAG07696.1 - 9.3e-228 756.8 0.1 1.3e-227 756.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 AAG07696.1 - 3.1e-05 24.2 0.0 5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 AAG07696.1 - 3.3e-05 24.2 0.2 0.023 15.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 AAG07696.1 - 0.00017 20.7 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 AAG07696.1 - 0.00024 21.5 8.2 0.0027 18.1 0.1 2.8 2 1 0 3 3 3 2 AAA ATPase domain ResIII PF04851.15 AAG07696.1 - 0.0005 20.1 0.0 0.0052 16.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 AAG07696.1 - 0.00058 19.3 0.0 0.0015 17.9 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF2075 PF09848.9 AAG07696.1 - 0.0012 18.2 0.1 1.1 8.4 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.7 AAG07696.1 - 0.002 17.1 0.0 0.29 10.0 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain CbiA PF01656.23 AAG07696.1 - 0.0034 17.4 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 AAG07696.1 - 0.016 14.9 0.2 0.016 14.9 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAG07696.1 - 0.021 15.1 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAG07696.1 - 0.031 13.8 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 AAG07696.1 - 0.038 14.4 0.1 2.4 8.6 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 AAG07696.1 - 0.065 12.9 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) T2SSE PF00437.20 AAG07696.1 - 0.09 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 AAG07696.1 - 0.13 11.8 0.2 0.35 10.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAG07696.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAG07696.1 - 0.15 11.6 0.1 0.38 10.4 0.1 1.5 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_6 PF12774.7 AAG07696.1 - 0.18 10.7 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region MCPsignal PF00015.21 AAG07697.1 - 2e-45 154.7 32.7 5.3e-45 153.3 22.9 2.3 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAG07697.1 - 1.1e-32 113.8 4.4 8.2e-32 110.9 0.0 3.1 2 1 1 3 3 3 1 Cache domain HAMP PF00672.25 AAG07697.1 - 4.8e-15 55.7 4.8 5.5e-14 52.3 0.4 3.8 3 1 0 3 3 2 1 HAMP domain dCache_2 PF08269.11 AAG07697.1 - 0.0011 18.2 2.2 0.017 14.3 0.0 3.2 3 1 1 4 4 4 1 Cache domain sCache_3_2 PF17203.4 AAG07697.1 - 0.0019 18.3 0.5 0.1 12.7 0.0 3.1 2 2 0 2 2 2 1 Single cache domain 3 Phage_DsbA PF11126.8 AAG07697.1 - 0.0024 18.0 0.0 0.008 16.4 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulator DsbA DUF948 PF06103.11 AAG07697.1 - 0.0032 17.7 24.1 0.064 13.5 2.2 5.4 2 1 3 6 6 6 2 Bacterial protein of unknown function (DUF948) Arfaptin PF06456.13 AAG07697.1 - 0.018 14.6 0.9 0.018 14.6 0.9 2.4 1 1 1 2 2 2 0 Arfaptin-like domain sCache_2 PF17200.4 AAG07697.1 - 0.087 12.7 1.7 0.27 11.1 0.0 2.6 3 0 0 3 3 3 0 Single Cache domain 2 HisKA PF00512.25 AAG07697.1 - 0.62 10.1 3.9 4.8 7.3 0.3 4.1 4 1 0 4 4 3 0 His Kinase A (phospho-acceptor) domain BLOC1_2 PF10046.9 AAG07697.1 - 0.84 10.0 14.1 1.9 8.8 0.5 4.2 2 2 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 kleA_kleC PF17383.2 AAG07697.1 - 0.88 9.9 10.6 0.62 10.4 1.5 3.4 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A DUF2408 PF10303.9 AAG07697.1 - 1 9.9 7.8 0.17 12.4 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF745 PF05335.13 AAG07697.1 - 1.7 8.4 25.2 0.37 10.5 6.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) WXG100 PF06013.12 AAG07697.1 - 3.1 8.1 14.0 7.5 6.9 0.6 4.6 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.11 AAG07697.1 - 5.2 7.7 9.0 1.3e+02 3.2 1.7 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3450 PF11932.8 AAG07697.1 - 6.2 6.0 21.0 2.6 7.3 7.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DASH_Dad4 PF08650.10 AAG07697.1 - 7.1 6.7 11.1 2.8 8.0 0.2 3.9 4 0 0 4 4 4 0 DASH complex subunit Dad4 HisKA_3 PF07730.13 AAG07697.1 - 7.4 7.2 9.9 8.1 7.0 1.2 3.8 3 0 0 3 3 3 0 Histidine kinase MCPsignal PF00015.21 AAG07698.1 - 7e-45 152.9 34.1 1e-44 152.4 23.4 2.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAG07698.1 - 2.7e-31 109.3 6.9 2.8e-31 109.2 0.0 3.1 2 1 1 3 3 3 1 Cache domain HAMP PF00672.25 AAG07698.1 - 1.7e-14 53.9 2.8 6.3e-13 48.9 0.2 3.7 3 1 0 3 3 2 1 HAMP domain DUF948 PF06103.11 AAG07698.1 - 0.00029 21.0 27.2 0.0072 16.6 5.3 5.7 2 1 3 6 6 6 2 Bacterial protein of unknown function (DUF948) dCache_2 PF08269.11 AAG07698.1 - 0.00086 18.6 0.0 0.00086 18.6 0.0 3.3 3 1 0 3 3 3 1 Cache domain sCache_2 PF17200.4 AAG07698.1 - 0.0027 17.6 3.0 0.021 14.7 0.0 3.4 4 0 0 4 4 4 1 Single Cache domain 2 sCache_3_2 PF17203.4 AAG07698.1 - 0.0044 17.2 1.1 0.16 12.1 0.0 3.2 2 1 0 2 2 2 1 Single cache domain 3 Arfaptin PF06456.13 AAG07698.1 - 0.1 12.1 6.2 0.023 14.3 1.0 2.4 2 1 1 3 3 3 0 Arfaptin-like domain BLOC1_2 PF10046.9 AAG07698.1 - 0.2 11.9 12.6 1.9 8.8 0.5 4.1 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 kleA_kleC PF17383.2 AAG07698.1 - 0.64 10.4 9.8 0.54 10.6 1.1 3.4 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A DUF2408 PF10303.9 AAG07698.1 - 4.5 7.8 9.6 0.37 11.3 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) HisKA PF00512.25 AAG07698.1 - 5.5 7.1 6.8 4 7.5 0.4 4.1 4 1 0 4 4 4 0 His Kinase A (phospho-acceptor) domain DUF3450 PF11932.8 AAG07698.1 - 7.4 5.8 22.8 1.9 7.7 8.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Glyco_transf_4 PF13439.6 AAG07699.1 - 2.9e-22 79.4 3.3 2.2e-21 76.6 2.2 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAG07699.1 - 1e-20 74.0 0.0 5.1e-20 71.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG07699.1 - 1.5e-20 74.0 0.1 5.3e-20 72.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAG07699.1 - 3.1e-13 50.5 3.8 3.1e-13 50.5 3.8 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAG07699.1 - 7.6e-10 39.0 0.1 1.6e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3880 PF12996.7 AAG07699.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) Epimerase_2 PF02350.19 AAG07699.1 - 0.11 11.3 0.2 0.42 9.4 0.1 1.9 3 0 0 3 3 3 0 UDP-N-acetylglucosamine 2-epimerase DUF2334 PF10096.9 AAG07700.1 - 2.6e-32 112.2 0.0 2.9e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) LPG_synthase_TM PF03706.13 AAG07701.1 - 8.6e-41 140.4 39.6 1.1e-40 140.1 39.6 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region HemY_N PF07219.13 AAG07701.1 - 0.062 13.5 0.7 0.062 13.5 0.7 2.7 3 0 0 3 3 3 0 HemY protein N-terminus Formyl_trans_N PF00551.19 AAG07702.1 - 6.9e-39 133.4 0.0 8.6e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 AAG07702.1 - 0.0015 18.2 0.0 0.0049 16.6 0.0 1.9 1 0 0 1 1 1 1 ACT domain DUF1147 PF06615.11 AAG07703.1 - 0.034 14.2 0.2 0.056 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) SPT16 PF08644.11 AAG07703.1 - 0.13 12.5 2.1 0.16 12.2 1.9 1.3 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) FapA PF03961.13 AAG07703.1 - 0.5 8.9 3.8 0.55 8.8 3.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_X-T_C PF08411.10 AAG07704.1 - 4.1e-97 324.5 0.1 5.5e-97 324.1 0.1 1.2 1 0 0 1 1 1 1 Exonuclease C-terminal RNase_T PF00929.24 AAG07704.1 - 5e-25 89.0 0.0 7.6e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease GPDPase_memb PF10110.9 AAG07705.1 - 0.00076 18.4 2.5 0.00076 18.4 2.5 3.0 1 1 2 3 3 3 2 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF975 PF06161.11 AAG07705.1 - 0.067 13.0 20.1 0.59 9.9 20.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF975) UPF0259 PF06790.11 AAG07705.1 - 1.8 8.2 13.6 0.62 9.8 10.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0259) RDD PF06271.12 AAG07706.1 - 2.6e-20 73.1 3.8 3.3e-20 72.7 3.8 1.1 1 0 0 1 1 1 1 RDD family SpoIIM PF01944.17 AAG07707.1 - 8e-36 123.4 8.9 1.4e-35 122.6 8.9 1.4 1 0 0 1 1 1 1 Stage II sporulation protein M DUF2892 PF11127.8 AAG07707.1 - 0.019 15.0 0.9 0.019 15.0 0.9 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2892) DUF4129 PF13559.6 AAG07708.1 - 1.6e-05 25.1 1.6 1.6e-05 25.1 1.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) DUF4350 PF14258.6 AAG07709.1 - 1.2e-13 51.2 0.1 4.1e-13 49.6 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) AAA_3 PF07726.11 AAG07710.1 - 5.3e-64 214.0 0.0 9.3e-64 213.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAG07710.1 - 2.7e-17 62.4 0.1 7.7e-17 60.9 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAG07710.1 - 5e-14 52.5 0.0 1.2e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAG07710.1 - 8.4e-06 26.2 0.0 1.8e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AAG07710.1 - 1.3e-05 25.0 0.1 0.00019 21.2 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 AAG07710.1 - 0.00018 22.0 0.6 0.00053 20.4 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 AAG07710.1 - 0.0024 17.6 0.1 0.0069 16.1 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 AAG07710.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 AAG07710.1 - 0.017 14.5 0.6 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAG07710.1 - 0.02 15.2 0.6 0.19 12.0 0.0 2.7 3 1 1 4 4 4 0 AAA domain STN PF07660.14 AAG07710.1 - 0.027 14.3 0.4 0.55 10.1 0.0 2.6 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain AAA_30 PF13604.6 AAG07710.1 - 0.071 12.8 0.1 0.24 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AAG07710.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF58 PF01882.18 AAG07711.1 - 2.7e-23 82.1 0.6 6.7e-23 80.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF58 VWA_2 PF13519.6 AAG07711.1 - 4.9e-06 27.1 0.0 8.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4131 PF13567.6 AAG07711.1 - 0.23 11.1 6.8 0.66 9.6 6.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CopD PF05425.13 AAG07711.1 - 0.5 10.8 9.7 0.15 12.5 6.6 1.8 2 0 0 2 2 2 0 Copper resistance protein D PilZ PF07238.14 AAG07712.1 - 2.7e-05 24.4 0.0 3.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 PilZ domain DUF4124 PF13511.6 AAG07713.1 - 4.9e-15 55.6 0.5 1.1e-14 54.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) DUF2514 PF10721.9 AAG07713.1 - 0.0018 18.3 3.7 0.0022 18.1 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) DUF4407 PF14362.6 AAG07713.1 - 0.61 9.4 4.8 0.88 8.9 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDRGK PF09756.9 AAG07713.1 - 4.5 6.8 8.1 85 2.7 8.3 2.0 1 1 1 2 2 2 0 DDRGK domain YfiO PF13525.6 AAG07714.1 - 0.0027 17.5 0.5 0.005 16.6 0.5 1.6 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_16 PF13432.6 AAG07714.1 - 0.0083 16.8 0.7 0.017 15.8 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_18 PF13512.6 AAG07714.1 - 0.04 14.0 0.5 0.084 13.0 0.2 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAG07715.1 - 1e-06 29.0 4.3 0.0025 18.3 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.12 AAG07715.1 - 7.7e-05 23.2 1.2 0.057 14.1 0.0 3.4 3 0 0 3 3 3 2 Sel1 repeat YfiO PF13525.6 AAG07715.1 - 0.0019 18.0 1.6 0.014 15.1 0.7 2.1 2 0 0 2 2 2 1 Outer membrane lipoprotein TPR_14 PF13428.6 AAG07715.1 - 0.15 13.0 9.3 4.1 8.5 0.2 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAG07715.1 - 0.83 9.8 9.6 8.6 6.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAG07715.1 - 1.2 9.1 7.0 87 3.2 0.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Usp PF00582.26 AAG07716.1 - 1.3e-32 113.3 0.2 2.4e-15 57.3 0.7 2.1 2 0 0 2 2 2 2 Universal stress protein family PK PF00224.21 AAG07717.1 - 1.3e-122 409.0 0.7 1.8e-122 408.6 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AAG07717.1 - 2.5e-27 95.4 0.1 1.2e-26 93.3 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain ECH_1 PF00378.20 AAG07718.1 - 2.9e-49 167.7 0.0 3.5e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG07718.1 - 1.7e-25 90.2 0.0 3.1e-25 89.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TP_methylase PF00590.20 AAG07718.1 - 0.015 15.2 0.3 0.075 13.0 0.0 1.9 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Fer2 PF00111.27 AAG07719.1 - 1.5e-15 56.9 1.6 2.8e-15 56.0 1.6 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AAG07719.1 - 9.7e-07 29.4 0.0 3.1e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2_4 PF13510.6 AAG07719.1 - 0.00096 19.2 0.1 0.0022 18.0 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 AAG07719.1 - 0.0012 19.1 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain TOBE_3 PF12857.7 AAG07719.1 - 0.0038 17.1 0.1 0.013 15.3 0.1 2.0 1 0 0 1 1 1 1 TOBE-like domain GGDEF PF00990.21 AAG07720.1 - 3.2e-43 147.3 0.1 5.4e-43 146.5 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAG07720.1 - 4.2e-05 23.8 1.6 4.2e-05 23.8 1.6 2.2 1 1 1 2 2 2 1 GGDEF-like domain DUF948 PF06103.11 AAG07720.1 - 0.18 12.1 0.1 0.91 9.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HlyD_D4 PF16572.5 AAG07720.1 - 0.27 11.1 2.0 30 4.6 0.0 3.3 2 1 1 3 3 3 0 Long alpha hairpin domain of cation efflux system protein, CusB Fumerase PF05681.14 AAG07721.1 - 5.7e-102 340.8 0.0 7.6e-102 340.3 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 AAG07721.1 - 5.9e-81 270.7 0.0 8.6e-81 270.2 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus Nramp PF01566.18 AAG07722.1 - 7.7e-132 439.6 15.1 9e-132 439.4 15.1 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein RHH_4 PF13467.6 AAG07723.1 - 2.4e-24 85.0 0.2 3.1e-24 84.6 0.2 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix domain Castor_Poll_mid PF06241.12 AAG07723.1 - 0.054 13.5 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel DJ-1_PfpI PF01965.24 AAG07724.1 - 1.7e-50 171.1 0.0 2e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AAG07724.1 - 0.00021 21.0 0.0 0.0014 18.4 0.0 2.1 1 1 1 2 2 2 1 ThiJ/PfpI family-like GATase PF00117.28 AAG07724.1 - 0.00055 19.7 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Catalase_C PF18011.1 AAG07724.1 - 0.0064 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Peptidase_C26 PF07722.13 AAG07724.1 - 0.0074 16.1 0.0 0.025 14.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 AAG07724.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF2846 PF11008.8 AAG07725.1 - 1.2e-27 95.8 0.0 1.6e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2846) Acyl_transf_3 PF01757.22 AAG07726.1 - 2.4e-30 105.8 34.2 2.8e-30 105.6 34.2 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF2070 PF09843.9 AAG07726.1 - 7.5 4.7 11.7 0.87 7.8 1.6 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) PLDc_2 PF13091.6 AAG07727.1 - 2e-39 134.5 0.0 1.7e-25 89.5 0.0 2.1 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAG07727.1 - 1.3e-08 34.6 0.4 0.00077 19.5 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif YceI PF04264.13 AAG07728.1 - 1.9e-07 31.7 0.0 2.3e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 YceI-like domain HTH_IclR PF09339.10 AAG07729.1 - 3.4e-15 55.6 4.3 9.7e-15 54.1 1.6 2.8 3 0 0 3 3 3 1 IclR helix-turn-helix domain MarR PF01047.22 AAG07729.1 - 1.6e-05 24.8 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 MarR family IclR PF01614.18 AAG07729.1 - 0.00079 19.3 0.1 0.013 15.4 0.1 2.3 1 1 0 1 1 1 1 Bacterial transcriptional regulator MarR_2 PF12802.7 AAG07729.1 - 0.0062 16.4 0.3 0.026 14.4 0.1 2.3 2 0 0 2 2 2 1 MarR family HTH_DeoR PF08220.12 AAG07729.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain GAF_2 PF13185.6 AAG07729.1 - 0.03 14.6 0.2 0.085 13.1 0.1 1.9 1 1 1 2 2 2 0 GAF domain GAF PF01590.26 AAG07729.1 - 0.084 13.5 0.4 0.15 12.7 0.4 1.9 1 1 0 1 1 1 0 GAF domain Rrf2 PF02082.20 AAG07729.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Penicillinase_R PF03965.16 AAG07729.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Penicillinase repressor Amidase PF01425.21 AAG07730.1 - 1e-88 298.3 0.0 1.5e-88 297.7 0.0 1.3 1 1 0 1 1 1 1 Amidase Sugar_tr PF00083.24 AAG07731.1 - 3.1e-30 105.4 26.6 2.7e-20 72.7 8.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAG07731.1 - 2.6e-24 85.8 54.2 1.7e-14 53.5 26.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2809 PF10990.8 AAG07731.1 - 2 9.1 7.6 9.4 7.0 0.1 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2809) Peptidase_M20 PF01546.28 AAG07732.1 - 3.5e-34 118.3 0.2 4.7e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAG07732.1 - 2.8e-11 43.3 0.6 4.2e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain YceI PF04264.13 AAG07733.1 - 1e-12 48.9 0.0 1.1e-12 48.7 0.0 1.1 1 0 0 1 1 1 1 YceI-like domain YycH PF07435.11 AAG07733.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 YycH protein DUF2784 PF10861.8 AAG07734.1 - 0.027 14.5 1.9 0.035 14.1 1.9 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF2784) DUF2770 PF10968.8 AAG07734.1 - 0.44 10.6 2.3 0.68 9.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) Beta-lactamase PF00144.24 AAG07735.1 - 4.9e-45 154.2 3.3 6.2e-45 153.9 3.3 1.1 1 0 0 1 1 1 1 Beta-lactamase Lactamase_B PF00753.27 AAG07736.1 - 4.3e-23 82.3 0.0 5.1e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAG07736.1 - 0.0012 18.3 0.1 0.0017 17.9 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Acyl-CoA_dh_M PF02770.19 AAG07737.1 - 6.1e-07 29.6 0.0 8.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF2555 PF10742.9 AAG07737.1 - 0.024 14.5 0.3 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Acetyltransf_5 PF13444.6 AAG07738.1 - 7.4e-30 103.6 0.1 1.1e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 AAG07738.1 - 0.055 13.0 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 Autoinducer synthase Acyltransferase PF01553.21 AAG07739.1 - 8.6e-21 74.0 0.0 1.4e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Usp PF00582.26 AAG07740.1 - 5.5e-57 192.2 3.8 1.7e-31 109.6 2.2 2.0 2 0 0 2 2 2 2 Universal stress protein family DNA_photolyase PF00875.18 AAG07740.1 - 0.037 14.0 0.2 0.069 13.2 0.2 1.5 1 0 0 1 1 1 0 DNA photolyase ACP_PD PF04336.12 AAG07741.1 - 2.1e-34 118.1 0.0 3.1e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Acyl carrier protein phosphodiesterase HTH_20 PF12840.7 AAG07742.1 - 8.1e-18 64.2 0.0 1.6e-17 63.3 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAG07742.1 - 1.2e-07 31.4 0.3 1.5e-06 28.0 0.1 2.3 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAG07742.1 - 0.00024 20.9 0.4 0.00029 20.7 0.4 1.3 1 1 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAG07742.1 - 0.00042 20.1 1.4 0.00082 19.1 1.4 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AAG07742.1 - 0.00061 19.3 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding RP-C PF03428.13 AAG07742.1 - 0.0055 16.4 0.1 0.0066 16.1 0.1 1.3 1 1 0 1 1 1 1 Replication protein C N-terminal domain HTH_Crp_2 PF13545.6 AAG07742.1 - 0.012 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_40 PF14493.6 AAG07742.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 AAG07742.1 - 0.025 14.9 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 AAG07742.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_36 PF13730.6 AAG07742.1 - 0.083 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_46 PF15977.5 AAG07742.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA binding MFS_1 PF07690.16 AAG07743.1 - 1.8e-38 132.4 51.1 1.8e-38 132.4 51.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG07743.1 - 3.5e-05 22.9 32.1 8.7e-05 21.6 27.4 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AAG07743.1 - 6.1e-05 22.5 46.5 7.8e-05 22.1 46.5 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 AAG07743.1 - 0.011 14.1 1.8 0.011 14.1 1.8 2.8 3 1 0 3 3 3 0 BT1 family DUF2417 PF10329.9 AAG07743.1 - 3.7 6.9 5.2 0.51 9.7 0.2 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Oxidored_FMN PF00724.20 AAG07744.1 - 1.2e-82 278.0 0.0 1.6e-82 277.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FeoC PF09012.10 AAG07745.1 - 5.1e-12 45.7 0.1 5.9e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 FeoC like transcriptional regulator FeoB_associated PF12669.7 AAG07745.1 - 0.012 16.0 4.4 0.015 15.7 4.4 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein HTH_IclR PF09339.10 AAG07745.1 - 0.029 14.2 0.3 0.039 13.8 0.3 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain FCH PF00611.23 AAG07745.1 - 0.2 12.0 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain FeoB_N PF02421.18 AAG07746.1 - 1.1e-62 210.2 0.0 1.8e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Gate PF07670.14 AAG07746.1 - 1.5e-48 163.7 17.7 2.6e-36 124.3 0.2 3.1 4 0 0 4 4 4 2 Nucleoside recognition FeoB_C PF07664.12 AAG07746.1 - 6e-22 77.1 1.5 6e-22 77.1 1.5 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B C terminus MMR_HSR1 PF01926.23 AAG07746.1 - 3e-19 69.2 0.0 6.9e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_Cyto PF17910.1 AAG07746.1 - 1.3e-07 32.0 0.0 5.4e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 FeoB cytosolic helical domain SRPRB PF09439.10 AAG07746.1 - 0.00014 21.3 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 AAG07746.1 - 0.0011 18.8 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 AAG07746.1 - 0.015 14.8 0.2 1.6 8.2 0.2 2.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PEP-utilizers PF00391.23 AAG07746.1 - 0.031 14.0 1.1 0.27 11.0 0.1 3.1 3 1 1 4 4 4 0 PEP-utilising enzyme, mobile domain Dynamin_N PF00350.23 AAG07746.1 - 0.098 12.7 0.1 6.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 AAG07746.1 - 0.11 12.3 0.0 21 4.8 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FeoA PF04023.14 AAG07747.1 - 2.5e-11 43.7 0.0 2.9e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 FeoA domain Syntaxin-6_N PF09177.11 AAG07748.1 - 0.0013 19.2 2.9 0.41 11.2 1.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF4763 PF15960.5 AAG07748.1 - 0.0042 16.4 16.3 0.041 13.2 8.4 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4763) Fez1 PF06818.15 AAG07748.1 - 0.0044 17.5 9.4 0.017 15.6 9.4 1.7 1 1 0 1 1 1 1 Fez1 CdvA PF18822.1 AAG07748.1 - 0.018 14.9 8.1 0.039 13.8 3.2 2.6 3 0 0 3 3 3 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 AAG07748.1 - 0.019 15.0 8.3 0.029 14.4 1.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 AAG07748.1 - 0.02 15.2 8.0 0.037 14.3 1.8 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.11 AAG07748.1 - 0.048 13.7 12.1 1.3 9.2 5.1 2.9 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Tropomyosin PF00261.20 AAG07748.1 - 0.069 12.5 6.8 0.16 11.3 0.8 2.5 1 1 1 3 3 3 0 Tropomyosin AAA_13 PF13166.6 AAG07748.1 - 0.13 10.8 4.9 0.26 9.9 4.8 1.5 1 1 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 AAG07748.1 - 0.14 12.2 15.4 1.7e+02 2.2 15.4 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 AAG07748.1 - 0.14 12.2 5.9 0.38 10.9 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) KASH_CCD PF14662.6 AAG07748.1 - 0.16 11.8 13.6 0.04 13.7 5.8 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 AAG07748.1 - 0.17 11.3 10.2 0.59 9.5 10.2 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 CC2-LZ PF16516.5 AAG07748.1 - 0.2 12.0 12.1 0.15 12.4 3.8 2.9 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Seryl_tRNA_N PF02403.22 AAG07748.1 - 0.21 11.9 14.8 0.26 11.5 1.5 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1216 PF06746.11 AAG07748.1 - 0.24 11.4 2.8 0.38 10.8 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) TMF_TATA_bd PF12325.8 AAG07748.1 - 0.26 11.5 11.0 0.63 10.3 6.8 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 AAG07748.1 - 0.26 11.7 14.1 0.61 10.5 5.9 2.7 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_GPO PF05929.11 AAG07748.1 - 0.35 10.4 13.3 0.063 12.9 7.6 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FliJ PF02050.16 AAG07748.1 - 0.37 11.0 21.6 2 8.7 11.8 2.3 1 1 0 2 2 2 0 Flagellar FliJ protein GAS PF13851.6 AAG07748.1 - 0.47 9.8 14.8 0.95 8.8 8.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 AAG07748.1 - 0.5 9.2 13.6 1.7 7.5 13.6 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 AAG07748.1 - 0.57 10.8 21.5 2.6 8.7 3.5 3.8 1 1 3 4 4 4 0 SlyX TMF_DNA_bd PF12329.8 AAG07748.1 - 0.59 10.2 14.0 0.71 9.9 0.4 3.1 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 AAG07748.1 - 0.66 10.2 18.7 0.35 11.1 11.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Flagellar_rod PF05149.12 AAG07748.1 - 0.83 9.1 11.7 0.47 9.9 7.1 2.0 2 0 0 2 2 2 0 Paraflagellar rod protein HOOK PF05622.12 AAG07748.1 - 0.93 7.6 13.8 2.3 6.3 13.8 1.6 1 1 0 1 1 1 0 HOOK protein COG2 PF06148.11 AAG07748.1 - 0.93 9.6 7.6 3.8 7.6 1.6 2.7 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.16 AAG07748.1 - 0.95 10.0 15.8 2.3 8.8 6.3 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 HrpB7 PF09486.10 AAG07748.1 - 1.1 9.7 11.3 4.2 7.7 3.6 2.7 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ABC_tran_CTD PF16326.5 AAG07748.1 - 1.6 9.0 13.6 15 5.9 0.0 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain TMPIT PF07851.13 AAG07748.1 - 1.8 7.7 7.6 0.6 9.3 3.8 1.8 1 1 1 2 2 2 0 TMPIT-like protein NPV_P10 PF05531.12 AAG07748.1 - 1.9 9.0 17.5 9.3 6.8 1.0 3.9 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 AAG07748.1 - 2.8 8.2 13.2 0.7 10.2 7.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) MscS_porin PF12795.7 AAG07748.1 - 3.2 7.2 31.1 0.62 9.6 15.5 2.4 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain HIP1_clath_bdg PF16515.5 AAG07748.1 - 3.9 8.1 18.5 0.93 10.1 9.5 2.6 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KELK PF15796.5 AAG07748.1 - 4.6 7.8 12.4 4 8.0 0.5 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase UPF0242 PF06785.11 AAG07748.1 - 5 7.2 10.9 18 5.4 10.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 AAG07748.1 - 6 7.6 9.2 6.8 7.4 1.4 3.0 2 1 1 3 3 3 0 Initiation control protein YabA FAM76 PF16046.5 AAG07748.1 - 6.4 6.0 10.4 15 4.9 0.2 2.1 1 1 1 2 2 2 0 FAM76 protein DUF2203 PF09969.9 AAG07748.1 - 6.6 7.5 6.8 7.9 7.2 3.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) EMP24_GP25L PF01105.24 AAG07748.1 - 8 6.4 6.7 2.4 8.1 1.3 2.3 1 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD WXG100 PF06013.12 AAG07748.1 - 8.7 6.6 20.3 4 7.7 2.0 3.6 1 1 3 4 4 4 0 Proteins of 100 residues with WXG Exonuc_VII_L PF02601.15 AAG07748.1 - 9.5 5.7 12.4 25 4.3 12.4 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Epimerase PF01370.21 AAG07749.1 - 1.9e-33 115.9 0.0 2.4e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAG07749.1 - 4.1e-29 101.5 0.0 5.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAG07749.1 - 6e-17 62.1 0.0 8.1e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AAG07749.1 - 1.1e-15 57.5 0.1 1.5e-13 50.5 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AAG07749.1 - 5.1e-13 49.1 0.0 2.3e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAG07749.1 - 1.3e-11 44.2 0.0 1.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AAG07749.1 - 6.7e-09 35.7 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 AAG07749.1 - 0.00037 20.0 0.0 0.00079 18.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 AAG07749.1 - 0.0008 18.6 0.0 0.0057 15.8 0.1 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 AAG07749.1 - 0.047 13.6 0.2 0.12 12.2 0.2 1.8 1 1 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 AAG07749.1 - 0.084 13.1 0.2 0.34 11.2 0.2 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_NADP PF03435.18 AAG07750.1 - 2.1e-11 44.2 0.0 3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AAG07750.1 - 9.6e-10 38.6 0.2 1.4e-09 38.2 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAG07750.1 - 0.00014 21.5 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_1 PF00126.27 AAG07751.1 - 1.1e-16 60.5 0.3 3.2e-16 59.0 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAG07751.1 - 1.7e-15 57.0 3.7 2.6e-15 56.3 3.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_AsnC-type PF13404.6 AAG07751.1 - 0.0019 18.0 1.5 0.0063 16.3 0.3 2.5 2 1 0 2 2 2 1 AsnC-type helix-turn-helix domain P22_Cro PF14549.6 AAG07751.1 - 0.0063 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro MarR_2 PF12802.7 AAG07751.1 - 0.013 15.4 1.7 0.045 13.6 0.3 2.7 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 AAG07751.1 - 0.016 14.8 0.1 0.038 13.5 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAG07751.1 - 0.023 14.8 0.5 0.1 12.7 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_50 PF18024.1 AAG07751.1 - 0.024 14.2 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 AAG07751.1 - 0.027 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Cro PF09048.10 AAG07751.1 - 0.11 12.5 0.1 0.38 10.8 0.3 1.7 2 0 0 2 2 2 0 Cro ACT_3 PF10000.9 AAG07752.1 - 1.4e-27 95.3 0.0 2.4e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 AAG07752.1 - 2.8e-11 43.0 0.0 3.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 ACT domain LysE PF01810.18 AAG07753.1 - 4.4e-42 143.7 15.7 5.2e-42 143.5 15.7 1.0 1 0 0 1 1 1 1 LysE type translocator Monooxygenase_B PF04744.12 AAG07753.1 - 0.42 9.4 2.7 0.99 8.2 1.6 1.9 2 0 0 2 2 2 0 Monooxygenase subunit B protein Sod_Fe_C PF02777.18 AAG07754.1 - 2e-40 137.1 0.0 1.7e-39 134.1 0.0 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AAG07754.1 - 1.3e-35 121.7 1.6 2.2e-35 121.0 1.6 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain EAL PF00563.20 AAG07755.1 - 1.7e-75 253.6 0.1 3e-75 252.8 0.1 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG07755.1 - 1.9e-38 131.8 0.4 4.2e-38 130.6 0.4 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Bac_export_3 PF01313.19 AAG07755.1 - 0.45 10.5 5.6 7.4 6.6 0.5 2.4 2 0 0 2 2 2 0 Bacterial export proteins, family 3 GIDE PF12483.8 AAG07756.1 - 3.8e-16 58.9 0.0 2.8e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 E3 Ubiquitin ligase EF-hand_1 PF00036.32 AAG07756.1 - 0.043 13.4 0.2 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 EF hand DUF1771 PF08590.10 AAG07756.1 - 0.083 13.3 1.1 0.13 12.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) DUF5380 PF17351.2 AAG07756.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5380) DUF1206 PF06724.11 AAG07756.1 - 0.65 10.1 6.7 5.6 7.1 1.6 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) LemA PF04011.12 AAG07757.1 - 1.1e-44 151.9 0.5 1.3e-44 151.7 0.5 1.0 1 0 0 1 1 1 1 LemA family DUF639 PF04842.12 AAG07757.1 - 0.053 12.9 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Peptidase_M75 PF09375.10 AAG07758.1 - 3.1e-97 325.5 5.9 4.1e-97 325.1 5.9 1.1 1 0 0 1 1 1 1 Imelysin DUF3347 PF11827.8 AAG07758.1 - 0.17 12.1 0.4 0.42 10.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) LPAM_2 PF13627.6 AAG07758.1 - 6.5 6.7 6.2 12 5.9 6.2 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DHOR PF06537.11 AAG07759.1 - 1.7e-140 468.9 0.0 2.2e-140 468.6 0.0 1.1 1 0 0 1 1 1 1 Di-haem oxidoreductase, putative peroxidase Cytochrom_C PF00034.21 AAG07759.1 - 2.4e-11 44.6 0.0 2.7e-06 28.4 0.0 2.8 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG07759.1 - 5.5e-05 23.4 0.1 0.11 12.8 0.0 2.8 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 AAG07759.1 - 0.003 17.2 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome_C7 PF14522.6 AAG07759.1 - 0.042 13.8 0.1 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Peptidase_M75 PF09375.10 AAG07760.1 - 5.3e-57 193.5 12.9 6.1e-57 193.3 12.9 1.0 1 0 0 1 1 1 1 Imelysin DUF1513 PF07433.11 AAG07761.1 - 6.5e-113 376.9 0.1 7.5e-113 376.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) Lactonase PF10282.9 AAG07761.1 - 0.0046 16.3 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Defensin_5 PF18251.1 AAG07761.1 - 0.036 14.2 0.2 0.074 13.2 0.2 1.4 1 0 0 1 1 1 0 Fungal defensin Copsin SGL PF08450.12 AAG07761.1 - 0.061 12.9 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region HlyD_D23 PF16576.5 AAG07762.1 - 3.9e-34 117.7 0.0 6.2e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG07762.1 - 4.2e-21 75.6 1.4 3.4e-19 69.5 0.0 2.8 3 0 0 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG07762.1 - 7.6e-08 32.1 0.4 3.7e-05 23.4 0.1 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAG07762.1 - 4.6e-06 26.4 0.0 0.047 13.5 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme RnfC_N PF13375.6 AAG07762.1 - 0.056 13.4 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ACR_tran PF00873.19 AAG07763.1 - 1e-273 910.7 19.1 1.2e-273 910.4 19.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG07763.1 - 3e-14 52.7 31.7 6.5e-08 31.9 10.0 2.4 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAG07763.1 - 0.0023 17.3 28.2 0.16 11.3 8.1 2.6 2 0 0 2 2 2 2 Protein export membrane protein Patched PF02460.18 AAG07763.1 - 4.3 5.3 9.3 11 4.0 9.3 1.6 1 0 0 1 1 1 0 Patched family NAPRTase PF04095.16 AAG07764.1 - 8e-83 277.7 0.0 9.8e-83 277.5 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 AAG07764.1 - 1.5e-33 115.8 0.1 3.8e-33 114.5 0.1 1.7 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Kdo PF06293.14 AAG07766.1 - 4e-74 248.5 0.3 4.5e-74 248.3 0.3 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AAG07766.1 - 0.074 13.0 1.0 0.14 12.0 1.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_25 PF13649.6 AAG07767.1 - 2e-13 50.8 0.0 3.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG07767.1 - 8e-13 48.9 0.0 1.4e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG07767.1 - 1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG07767.1 - 1e-06 29.4 0.0 1.8e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG07767.1 - 1.6e-06 28.1 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAG07767.1 - 0.0004 19.8 0.0 0.00084 18.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 AAG07767.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HATPase_c PF02518.26 AAG07768.1 - 5.4e-17 62.3 0.0 9.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG07768.1 - 4.1e-13 49.2 0.4 1.4e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAG07768.1 - 9.2e-08 32.4 3.0 1.9e-07 31.3 0.5 2.3 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 AAG07768.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAG07769.1 - 2.7e-30 104.8 0.0 7.4e-30 103.4 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG07769.1 - 1.5e-18 66.7 0.0 2.9e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal PAP2 PF01569.21 AAG07770.1 - 6.5e-15 55.1 3.1 1.3e-14 54.1 3.1 1.5 1 0 0 1 1 1 1 PAP2 superfamily 7TMR-DISM_7TM PF07695.11 AAG07770.1 - 0.46 10.3 12.8 1.7 8.5 1.6 2.7 2 1 0 2 2 2 0 7TM diverse intracellular signalling CRCB PF02537.15 AAG07771.1 - 3.4e-24 85.0 7.6 4.1e-24 84.7 7.6 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) CbtB PF09489.10 AAG07771.1 - 3.3 7.9 9.7 2.3 8.4 0.5 3.1 3 1 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) ParBc_2 PF08857.11 AAG07772.1 - 1.5e-46 158.5 0.0 1.9e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Putative ParB-like nuclease Cpn60_TCP1 PF00118.24 AAG07773.1 - 4.4e-94 315.8 19.6 7.5e-94 315.1 19.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family REF PF05755.12 AAG07773.1 - 0.25 11.1 1.9 0.35 10.6 0.6 1.9 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Cpn10 PF00166.21 AAG07774.1 - 4.3e-32 110.0 0.2 4.8e-32 109.9 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit FxsA PF04186.13 AAG07775.1 - 1.8e-34 118.1 9.8 2.3e-34 117.8 9.8 1.1 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein MMPL PF03176.15 AAG07775.1 - 0.25 10.2 3.7 0.32 9.9 3.7 1.2 1 0 0 1 1 1 0 MMPL family Phage_holin_3_6 PF07332.11 AAG07775.1 - 9.7 6.3 19.6 0.67 10.0 10.3 2.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pyrid_oxidase_2 PF13883.6 AAG07776.1 - 2.9e-14 53.4 0.0 4.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 AAG07776.1 - 9.8e-14 51.7 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 AAG07776.1 - 1.7e-12 47.4 0.0 2.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short_C2 PF13561.6 AAG07777.1 - 9.6e-56 188.9 4.3 1.2e-55 188.6 4.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG07777.1 - 1.6e-53 181.0 5.3 2.1e-53 180.7 5.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG07777.1 - 4.1e-18 65.9 4.3 1.1e-17 64.5 4.3 1.6 1 1 0 1 1 1 1 KR domain DUF481 PF04338.12 AAG07778.1 - 1.8e-49 168.7 10.3 2.5e-49 168.2 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF481 SH3_19 PF18597.1 AAG07778.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Myosin X N-terminal SH3 domain BBP2_2 PF10082.9 AAG07778.1 - 0.024 13.5 2.6 0.08 11.8 0.1 2.3 2 1 0 2 2 2 0 Putative beta-barrel porin 2 Hfq PF17209.3 AAG07778.1 - 0.03 14.0 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Hfq protein DUF481 PF04338.12 AAG07779.1 - 3.9e-32 112.0 1.3 5.1e-32 111.6 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF481 HlyD PF00529.20 AAG07779.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS DNA_binding_1 PF01035.20 AAG07780.1 - 1.9e-20 72.8 0.1 2.4e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain MFS_1 PF07690.16 AAG07781.1 - 6.6e-10 38.4 71.8 6.2e-06 25.4 39.4 3.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Acatn PF13000.7 AAG07781.1 - 1.1e-08 34.1 8.0 3.1e-07 29.3 2.2 2.3 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 MS_channel PF00924.18 AAG07782.1 - 6.3e-50 169.6 0.6 8.3e-50 169.2 0.6 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel TM_helix PF05552.12 AAG07782.1 - 7.4e-08 32.2 0.2 7.4e-08 32.2 0.2 2.8 3 1 0 3 3 3 1 Conserved TM helix Cyt_c_ox_IV PF12270.8 AAG07782.1 - 0.18 11.9 0.4 0.18 11.9 0.4 2.3 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF520 PF04461.13 AAG07783.1 - 8.4e-62 208.0 3.7 9.4e-62 207.9 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) DUF4974 PF16344.5 AAG07783.1 - 0.014 15.4 0.0 0.086 12.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) DUF1948 PF09185.10 AAG07783.1 - 0.051 13.4 0.5 0.098 12.5 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1948) GNAT_like PF18407.1 AAG07783.1 - 0.13 12.6 0.0 27 5.2 0.0 2.2 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain DUF5398 PF17376.2 AAG07783.1 - 0.17 12.5 3.9 0.48 11.1 0.1 2.6 1 1 2 3 3 3 0 Family of unknown function (DUF5398) Response_reg PF00072.24 AAG07784.1 - 1.5e-21 76.7 0.0 2.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GGDEF PF00990.21 AAG07784.1 - 3.1e-12 46.6 0.0 6.8e-12 45.4 0.0 1.6 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain ApbA PF02558.16 AAG07785.1 - 1.1e-34 119.3 0.0 1.6e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 AAG07785.1 - 7.8e-32 110.1 0.0 1.1e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal 3HCDH_N PF02737.18 AAG07785.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAG07785.1 - 0.025 15.1 0.1 0.22 12.1 0.0 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HATPase_c PF02518.26 AAG07786.1 - 9.6e-21 74.4 0.0 1.7e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG07786.1 - 2.9e-11 43.2 4.9 8.7e-10 38.5 0.3 4.0 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAG07786.1 - 2e-09 37.5 0.1 1.6e-08 34.5 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 AAG07786.1 - 2.5e-09 37.4 0.0 7.3e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold HAMP PF00672.25 AAG07786.1 - 3.7e-09 36.8 2.4 1.8e-08 34.6 2.4 2.3 1 0 0 1 1 1 1 HAMP domain PAS_8 PF13188.7 AAG07786.1 - 2.2e-05 24.3 0.0 8.9e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 PAS domain CHASE8 PF17152.4 AAG07786.1 - 0.00058 20.1 0.0 0.0017 18.6 0.0 1.8 1 0 0 1 1 1 1 Periplasmic sensor domain HATPase_c_3 PF13589.6 AAG07786.1 - 0.0092 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CALCOCO1 PF07888.11 AAG07786.1 - 0.0094 14.9 6.8 0.015 14.2 6.8 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like PAS_7 PF12860.7 AAG07786.1 - 0.068 13.3 2.6 1.8 8.8 0.0 3.7 4 0 0 4 4 4 0 PAS fold PAS_9 PF13426.7 AAG07786.1 - 0.082 13.2 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 PAS domain YabA PF06156.13 AAG07786.1 - 0.16 12.6 2.0 9.4 6.9 1.7 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Cob_adeno_trans PF01923.18 AAG07787.1 - 5.7e-56 189.2 0.0 6.7e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase TMP-TENI PF02581.17 AAG07788.1 - 7.2e-34 116.7 0.0 1e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase NUDIX_4 PF14815.6 AAG07788.1 - 6.7e-22 77.6 0.0 1.4e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 AAG07788.1 - 2.5e-19 69.6 1.4 4.2e-19 68.9 1.4 1.4 1 0 0 1 1 1 1 NUDIX domain FMN_dh PF01070.18 AAG07788.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase GST_N_3 PF13417.6 AAG07789.1 - 4.3e-12 46.3 0.0 7.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG07789.1 - 2.2e-08 34.3 0.0 3.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAG07789.1 - 4.1e-07 29.9 1.1 7.5e-07 29.1 1.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAG07789.1 - 8.3e-06 26.1 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_4 PF14834.6 AAG07789.1 - 0.0013 19.1 0.1 0.002 18.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Thioesterase PF00975.20 AAG07789.1 - 0.006 16.7 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain GST_N_4 PF17172.4 AAG07789.1 - 0.015 16.0 0.0 0.035 14.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Microvir_H PF04687.12 AAG07789.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) ArgJ PF01960.18 AAG07790.1 - 2.1e-136 454.6 7.7 2.3e-136 454.4 7.7 1.0 1 0 0 1 1 1 1 ArgJ family SecA_DEAD PF07517.14 AAG07791.1 - 1.2e-133 444.8 0.2 2.7e-133 443.7 0.2 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 AAG07791.1 - 1.1e-67 227.9 5.9 3.3e-67 226.4 5.9 1.9 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 AAG07791.1 - 1.3e-34 119.2 0.5 4e-34 117.6 0.1 2.2 2 0 0 2 2 2 1 SecA preprotein cross-linking domain SEC-C PF02810.15 AAG07791.1 - 1.4e-10 40.9 9.1 2.2e-10 40.2 9.1 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 AAG07791.1 - 0.0021 17.9 0.0 0.0088 15.8 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG07791.1 - 0.0072 16.7 3.5 0.082 13.3 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Peptidase_M23 PF01551.22 AAG07792.1 - 4.1e-32 110.3 2.9 7.8e-32 109.4 2.9 1.5 1 0 0 1 1 1 1 Peptidase family M23 RnfC_N PF13375.6 AAG07792.1 - 0.086 12.8 0.2 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 AAG07792.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Biotin-requiring enzyme MscS_porin PF12795.7 AAG07792.1 - 0.22 11.0 5.8 3.5 7.1 1.3 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Biotin_lipoyl_2 PF13533.6 AAG07792.1 - 0.31 10.9 2.1 0.66 9.9 0.2 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like MerR-DNA-bind PF09278.11 AAG07792.1 - 1.6 9.4 8.0 8.6 7.0 3.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding ABC_tran_CTD PF16326.5 AAG07792.1 - 1.7 8.9 6.6 3.2 8.1 0.3 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DASH_Hsk3 PF08227.11 AAG07792.1 - 4.3 7.8 7.2 2.7 8.4 0.4 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DciA PF05258.12 AAG07793.1 - 2.1e-09 37.6 2.3 2.3e-09 37.5 0.5 1.9 2 1 0 2 2 2 1 Dna[CI] antecedent, DciA LpxC PF03331.13 AAG07794.1 - 3.1e-109 364.7 0.0 3.5e-109 364.5 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Tubulin PF00091.25 AAG07795.1 - 2.7e-40 138.7 0.5 4.4e-40 138.0 0.5 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AAG07795.1 - 3.3e-36 123.5 0.9 7.6e-36 122.3 0.9 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NmrA PF05368.13 AAG07795.1 - 0.00099 18.7 0.2 0.048 13.2 0.0 2.8 2 1 1 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.6 AAG07795.1 - 0.0056 16.6 1.5 0.013 15.4 0.1 2.3 2 1 1 3 3 3 1 NAD(P)H-binding Tubulin_2 PF13809.6 AAG07795.1 - 0.24 10.5 8.7 4.2 6.4 0.2 2.8 1 1 1 2 2 2 0 Tubulin like FtsA PF14450.6 AAG07796.1 - 7.3e-40 135.6 1.8 4.4e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 AAG07796.1 - 7.6e-32 109.6 3.5 1.1e-31 109.0 0.7 2.6 3 0 0 3 3 3 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 AAG07796.1 - 3.4e-16 59.0 6.2 1.9e-15 56.5 0.3 2.8 2 2 1 3 3 3 2 MreB/Mbl protein EutA PF06277.11 AAG07796.1 - 1.2e-06 27.7 2.7 3e-06 26.4 0.2 2.5 2 1 0 3 3 3 1 Ethanolamine utilisation protein EutA PilM_2 PF11104.8 AAG07796.1 - 1.9e-05 23.9 1.6 0.0068 15.5 1.7 3.5 2 1 0 2 2 2 1 Type IV pilus assembly protein PilM; HSP70 PF00012.20 AAG07796.1 - 6.3e-05 21.4 0.2 0.0064 14.7 0.1 3.1 3 1 1 4 4 4 1 Hsp70 protein DDR PF08841.10 AAG07796.1 - 0.00014 21.0 4.0 0.00024 20.2 4.0 1.5 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain MutL PF13941.6 AAG07796.1 - 0.02 13.5 1.1 0.057 12.0 0.1 2.2 2 0 0 2 2 2 0 MutL protein Actin PF00022.19 AAG07796.1 - 0.026 13.2 0.2 0.38 9.3 0.0 2.4 3 0 0 3 3 3 0 Actin SrfB PF07520.11 AAG07796.1 - 0.033 12.1 0.1 0.046 11.6 0.1 1.1 1 0 0 1 1 1 0 Virulence factor SrfB Ppx-GppA PF02541.16 AAG07796.1 - 0.044 13.2 0.3 0.11 11.9 0.3 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family FtsQ PF03799.15 AAG07797.1 - 8.4e-24 84.6 0.1 2.1e-23 83.4 0.2 1.6 2 0 0 2 2 2 1 Cell division protein FtsQ POTRA_1 PF08478.10 AAG07797.1 - 1.8e-18 66.6 0.1 8.8e-18 64.4 0.0 2.1 2 0 0 2 2 2 1 POTRA domain, FtsQ-type Dala_Dala_lig_C PF07478.13 AAG07798.1 - 2.1e-56 190.7 0.0 2.6e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AAG07798.1 - 1.1e-19 70.8 0.6 2.9e-18 66.2 0.6 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus CPSase_L_D2 PF02786.17 AAG07798.1 - 1.7e-09 37.5 0.0 4.1e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AAG07798.1 - 2.8e-08 33.5 0.0 5.9e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAG07798.1 - 7.2e-08 32.2 0.0 3.8e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAG07798.1 - 0.00015 21.8 0.0 0.00034 20.7 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AAG07798.1 - 0.012 15.3 0.0 0.92 9.1 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAG07798.1 - 0.017 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 AAG07798.1 - 0.038 13.2 0.0 2.8 7.1 0.0 2.4 2 1 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 AAG07798.1 - 0.053 13.3 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 AAG07798.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 AAG07798.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TTL PF03133.15 AAG07798.1 - 0.15 11.2 0.0 0.53 9.4 0.0 1.7 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family Mur_ligase_M PF08245.12 AAG07799.1 - 7.4e-28 97.9 0.0 1e-27 97.4 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AAG07799.1 - 8.6e-28 96.5 1.2 4e-27 94.4 0.2 2.3 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AAG07799.1 - 2.7e-21 75.6 0.0 9.8e-21 73.8 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain F420_oxidored PF03807.17 AAG07799.1 - 0.028 15.0 0.2 0.073 13.7 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_28 PF03033.20 AAG07800.1 - 4.2e-41 140.2 0.0 7.9e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 AAG07800.1 - 7.7e-36 123.6 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 AAG07800.1 - 1.8e-06 28.5 0.9 1.8e-06 28.5 0.9 2.5 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AAG07800.1 - 0.0029 17.6 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_3 PF13528.6 AAG07800.1 - 0.0056 16.0 0.0 0.0086 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 FTSW_RODA_SPOVE PF01098.19 AAG07801.1 - 2.4e-103 345.9 24.8 3.1e-103 345.6 24.8 1.0 1 0 0 1 1 1 1 Cell cycle protein Mur_ligase_M PF08245.12 AAG07802.1 - 4.1e-26 92.2 0.0 5.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAG07802.1 - 8.6e-09 35.5 0.0 1.4e-07 31.6 0.0 2.5 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain TrkA_N PF02254.18 AAG07802.1 - 0.0032 17.7 0.0 0.012 15.9 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Glycos_transf_4 PF00953.21 AAG07803.1 - 1e-36 126.3 13.9 1e-36 126.3 13.9 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 AAG07803.1 - 4.7e-05 22.7 1.6 4.7e-05 22.7 1.6 2.9 3 0 0 3 3 3 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Mur_ligase_M PF08245.12 AAG07804.1 - 1e-47 162.7 0.0 1.5e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAG07804.1 - 8.4e-13 48.4 0.0 2.6e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AAG07804.1 - 2.1e-10 40.8 0.1 8.3e-10 38.9 0.1 2.1 1 0 0 1 1 1 1 Mur ligase family, catalytic domain POR PF01558.18 AAG07804.1 - 0.039 14.0 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Mur_ligase_M PF08245.12 AAG07805.1 - 1.8e-51 174.9 0.0 2.5e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAG07805.1 - 6e-24 84.1 0.2 8e-23 80.5 0.0 2.8 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AAG07805.1 - 1.5e-12 47.6 0.9 6.6e-12 45.6 0.2 2.5 3 0 0 3 3 3 1 Mur ligase family, catalytic domain RuvA_C PF07499.13 AAG07805.1 - 0.038 14.5 0.0 1.5 9.4 0.0 3.1 2 0 0 2 2 2 0 RuvA, C-terminal domain Glycos_transf_2 PF00535.26 AAG07805.1 - 0.14 11.9 0.1 7.5 6.3 0.0 2.4 1 1 1 2 2 2 0 Glycosyl transferase family 2 Transpeptidase PF00905.22 AAG07806.1 - 1.5e-85 287.1 0.1 1.8e-85 286.8 0.1 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AAG07806.1 - 2.5e-19 70.3 0.0 1.6e-17 64.5 0.0 2.4 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain FtsL PF04999.13 AAG07807.1 - 2.1e-32 111.0 0.1 2.3e-32 110.9 0.1 1.0 1 0 0 1 1 1 1 Cell division protein FtsL Methyltransf_5 PF01795.19 AAG07808.1 - 5.9e-111 370.9 0.0 6.8e-111 370.7 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 AAG07808.1 - 0.0025 17.7 0.0 0.043 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG07808.1 - 0.027 15.2 0.0 0.079 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF655 PF04919.12 AAG07808.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF655) MraZ PF02381.18 AAG07809.1 - 4.9e-35 119.4 0.1 3.1e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like TP_methylase PF00590.20 AAG07810.1 - 1.8e-28 99.9 0.1 2.7e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases RecO_C PF02565.15 AAG07810.1 - 0.033 14.0 0.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Recombination protein O C terminal LppC PF04348.13 AAG07811.1 - 8.1e-222 737.8 23.9 9.2e-222 737.6 23.9 1.0 1 0 0 1 1 1 1 LppC putative lipoprotein Peripla_BP_6 PF13458.6 AAG07811.1 - 2.7e-08 33.9 6.9 8.1e-08 32.3 6.9 1.8 1 1 0 1 1 1 1 Periplasmic binding protein UPF0102 PF02021.17 AAG07812.1 - 6.5e-26 90.4 0.1 7.6e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NERD PF08378.11 AAG07812.1 - 0.021 15.3 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Nuclease-related domain DUF234 PF03008.14 AAG07812.1 - 0.028 14.8 0.0 0.15 12.5 0.0 1.9 1 1 1 2 2 2 0 Archaea bacterial proteins of unknown function SIS_2 PF13580.6 AAG07813.1 - 8.9e-36 123.0 0.1 1.1e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AAG07813.1 - 1.5e-06 28.1 0.1 2.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 SIS domain Denso_VP4 PF02336.15 AAG07813.1 - 0.15 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Capsid protein VP4 BON PF04972.17 AAG07814.1 - 1.6e-30 105.2 7.5 2.1e-17 63.2 0.2 2.1 2 0 0 2 2 2 2 BON domain SspB PF04386.13 AAG07815.1 - 2.8e-35 121.6 0.0 8.1e-35 120.1 0.0 1.6 1 1 0 1 1 1 1 Stringent starvation protein B GST_N_3 PF13417.6 AAG07816.1 - 1.3e-15 57.6 0.2 2.3e-15 56.7 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAG07816.1 - 7.8e-11 42.2 0.0 1.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG07816.1 - 2.8e-09 37.2 0.0 6.2e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAG07816.1 - 3.9e-08 33.4 0.0 6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAG07816.1 - 3.5e-07 30.1 0.2 1.1e-06 28.6 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 AAG07816.1 - 0.005 17.0 0.1 0.048 13.9 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Cytochrom_C1 PF02167.15 AAG07817.1 - 3.8e-15 56.2 0.4 8e-10 38.8 0.0 2.9 1 1 1 2 2 2 2 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 AAG07817.1 - 0.0037 17.6 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG07817.1 - 0.11 13.6 0.5 0.24 12.5 0.5 1.7 1 1 0 1 1 1 0 Cytochrome c Cytochrome_B PF00033.19 AAG07818.1 - 9.4e-68 227.8 16.2 9.4e-68 227.8 16.2 2.4 3 0 0 3 3 3 1 Cytochrome b/b6/petB Cytochrom_B_C PF00032.17 AAG07818.1 - 2.5e-43 146.6 4.0 2.5e-43 146.6 4.0 3.9 4 1 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N_2 PF13631.6 AAG07818.1 - 6e-42 143.5 7.7 6e-42 143.5 7.7 2.3 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB UCR_Fe-S_N PF10399.9 AAG07819.1 - 3.9e-12 45.3 4.1 5.8e-12 44.8 4.1 1.3 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Rieske PF00355.26 AAG07819.1 - 1.6e-10 40.7 0.0 2.5e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 AAG07819.1 - 1.6 8.7 6.8 3.5 7.6 6.8 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Ribosomal_S9 PF00380.19 AAG07820.1 - 5.8e-47 159.2 0.9 6.5e-47 159.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.18 AAG07821.1 - 7.2e-59 197.5 0.1 8.3e-59 197.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Aldo_ket_red PF00248.21 AAG07822.1 - 5.9e-66 222.6 0.0 6.9e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acyl-CoA_dh_1 PF00441.24 AAG07823.1 - 8e-46 156.0 0.9 1.1e-45 155.5 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG07823.1 - 3.2e-37 127.6 0.0 1.1e-36 125.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAG07823.1 - 9.9e-28 96.2 0.1 1.9e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG07823.1 - 1.8e-15 57.4 0.1 2.6e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAG07823.1 - 0.17 11.5 0.2 0.43 10.2 0.2 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal HTH_18 PF12833.7 AAG07824.1 - 1.6e-20 73.2 1.6 1.6e-20 73.2 1.6 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG07824.1 - 5.4e-15 55.1 0.6 2.1e-06 27.7 0.3 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 AAG07824.1 - 3e-06 27.2 0.0 4.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family AFG1_ATPase PF03969.16 AAG07826.1 - 1e-169 564.2 0.2 1.2e-169 564.0 0.2 1.0 1 0 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 AAG07826.1 - 0.22 11.9 1.1 2 8.8 0.0 2.7 2 2 1 3 3 3 0 AAA ATPase domain BPS1 PF05633.11 AAG07826.1 - 0.46 9.4 2.8 14 4.5 0.3 2.7 3 0 0 3 3 3 0 Protein BYPASS1-related tRNA-synt_1b PF00579.25 AAG07827.1 - 7.3e-50 169.9 0.0 9.4e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1508 PF07411.12 AAG07827.1 - 0.00065 19.5 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1508) tRNA-synt_1f PF01921.18 AAG07827.1 - 0.095 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Thioesterase PF00975.20 AAG07828.1 - 3.7e-09 37.0 0.2 8.5e-09 35.9 0.1 1.5 1 1 1 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 AAG07828.1 - 1.3e-07 31.2 0.4 1e-06 28.2 0.2 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG07828.1 - 3.2e-07 30.3 0.1 0.0005 19.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1043 PF06295.12 AAG07829.1 - 1.5e-20 73.5 0.1 2e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) DUF948 PF06103.11 AAG07829.1 - 0.004 17.4 0.0 0.0056 16.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 AAG07829.1 - 0.0063 17.0 1.0 0.019 15.5 0.9 1.9 1 1 0 1 1 1 1 YtxH-like protein UPF0242 PF06785.11 AAG07829.1 - 0.053 13.6 2.1 0.071 13.2 2.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RskA PF10099.9 AAG07829.1 - 0.12 12.7 4.5 2.8 8.2 0.2 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Prominin PF05478.11 AAG07829.1 - 0.15 9.9 0.0 0.17 9.8 0.0 1.0 1 0 0 1 1 1 0 Prominin APS_kinase PF01583.20 AAG07830.1 - 1.2e-52 178.0 0.0 2e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase GTP_EFTU PF00009.27 AAG07830.1 - 1.3e-44 152.0 0.1 2.6e-44 151.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAG07830.1 - 3.9e-09 36.6 0.1 1.8e-05 24.8 0.0 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 AAG07830.1 - 7.8e-07 29.4 0.0 6.8e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain GTP_EFTU_D2 PF03144.25 AAG07830.1 - 2.4e-06 27.8 0.5 9.3e-06 25.9 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 AAG07830.1 - 0.00019 21.4 0.2 0.57 10.1 0.0 3.4 2 1 1 3 3 3 1 RsgA GTPase Zeta_toxin PF06414.12 AAG07830.1 - 0.00055 19.3 0.0 0.00093 18.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 AAG07830.1 - 0.0021 17.8 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 AAG07830.1 - 0.0027 17.5 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 AAG07830.1 - 0.0028 18.2 0.1 0.014 15.9 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 AAG07830.1 - 0.0033 17.8 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 AAG07830.1 - 0.019 15.2 0.2 14 5.9 0.0 3.2 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 AAG07830.1 - 0.02 14.1 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit GTP_EFTU_D3 PF03143.17 AAG07830.1 - 0.035 14.4 0.0 0.096 13.0 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain CbiA PF01656.23 AAG07830.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 AAG07830.1 - 0.058 13.2 0.0 7.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 AAG07830.1 - 0.063 12.7 0.1 1.6 8.1 0.0 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 AAG07830.1 - 0.065 13.7 0.0 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PEPCK_ATP PF01293.20 AAG07830.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase ATP_bind_2 PF03668.15 AAG07830.1 - 0.099 11.9 0.1 11 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop ATPase protein family KTI12 PF08433.10 AAG07830.1 - 0.17 11.3 0.0 0.44 9.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PAPS_reduct PF01507.19 AAG07831.1 - 2e-67 226.6 0.0 2.4e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SLT_2 PF13406.6 AAG07832.1 - 2.3e-92 309.3 0.0 2.6e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AAG07832.1 - 0.043 14.3 0.0 0.078 13.5 0.0 1.5 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT PF01464.20 AAG07832.1 - 0.048 13.3 0.0 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 Transglycosylase SLT domain NIF3 PF01784.18 AAG07833.1 - 1e-57 195.6 0.0 1.2e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) mTERF PF02536.14 AAG07833.1 - 0.047 12.6 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 mTERF Trypsin_2 PF13365.6 AAG07834.1 - 1.4e-30 107.2 0.5 2.4e-30 106.4 0.5 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAG07834.1 - 9.9e-16 57.8 0.4 2.7e-15 56.4 0.1 1.8 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 AAG07834.1 - 2.6e-12 47.0 0.0 4.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ PF00595.24 AAG07834.1 - 8.3e-09 35.7 0.3 7.8e-08 32.6 0.2 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 AAG07834.1 - 2.9e-07 30.2 1.6 1.3e-06 28.1 0.4 2.5 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 AAG07834.1 - 0.053 12.2 2.5 0.96 8.0 0.4 2.3 3 0 0 3 3 3 0 Peptidase S46 Aminotran_1_2 PF00155.21 AAG07835.1 - 7.2e-54 183.3 0.0 8.1e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ACT PF01842.25 AAG07835.1 - 0.15 11.9 0.1 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 ACT domain Histidinol_dh PF00815.20 AAG07836.1 - 8.1e-169 561.9 0.3 9.2e-169 561.8 0.3 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase HisG PF01634.18 AAG07837.1 - 1.1e-45 155.5 0.0 1.3e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Bacteriocin_IId PF09221.10 AAG07837.1 - 0.14 12.4 0.4 2.4 8.4 0.1 2.5 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like EPSP_synthase PF00275.20 AAG07838.1 - 3.7e-119 398.1 1.1 4.2e-119 397.9 1.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) BolA PF01722.18 AAG07839.1 - 6.3e-08 32.8 0.0 1e-07 32.1 0.0 1.3 1 1 0 1 1 1 1 BolA-like protein STAS_2 PF13466.6 AAG07840.1 - 1.4e-16 60.6 2.2 1.8e-16 60.2 2.2 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAG07840.1 - 1.4e-05 24.7 0.0 1.5e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 STAS domain TrbC_Ftype PF09673.10 AAG07840.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein MlaC PF05494.12 AAG07841.1 - 3.3e-43 147.3 0.2 3.9e-43 147.1 0.2 1.1 1 0 0 1 1 1 1 MlaC protein UPF0113_N PF17833.1 AAG07841.1 - 0.042 14.4 0.0 0.079 13.5 0.0 1.5 1 0 0 1 1 1 0 UPF0113 Pre-PUA domain MlaD PF02470.20 AAG07842.1 - 2.2e-20 72.7 1.6 2.2e-20 72.7 1.6 1.5 2 0 0 2 2 2 1 MlaD protein TraW_N PF12477.8 AAG07842.1 - 0.041 13.8 1.4 0.1 12.5 1.4 1.7 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal MlaE PF02405.16 AAG07843.1 - 2.8e-77 259.2 15.3 4.2e-77 258.6 15.3 1.3 1 0 0 1 1 1 1 Permease MlaE ABC_tran PF00005.27 AAG07844.1 - 1.1e-30 107.0 0.0 1.3e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07844.1 - 1.3e-07 31.8 0.1 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG07844.1 - 2.1e-05 24.9 0.0 3.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAG07844.1 - 0.00026 21.0 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 AAG07844.1 - 0.0013 18.6 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 AAG07844.1 - 0.0016 18.9 0.0 0.0024 18.3 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAG07844.1 - 0.0026 18.0 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAG07844.1 - 0.0033 17.0 0.0 0.0089 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAG07844.1 - 0.0034 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG07844.1 - 0.0039 17.7 0.0 0.0056 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AAG07844.1 - 0.0077 15.6 0.1 0.073 12.4 0.0 2.0 2 0 0 2 2 2 1 KaiC NACHT PF05729.12 AAG07844.1 - 0.0077 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 AAG07844.1 - 0.0082 16.1 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AAG07844.1 - 0.0093 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 AAG07844.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 AAG07844.1 - 0.028 14.9 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAG07844.1 - 0.035 14.4 0.1 0.081 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAG07844.1 - 0.041 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AAG07844.1 - 0.047 13.3 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 AAG07844.1 - 0.057 13.0 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 AAG07844.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AAG07844.1 - 0.064 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase ABC_ATPase PF09818.9 AAG07844.1 - 0.072 11.9 0.3 1.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 AAG07844.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Sbt_1 PF05982.12 AAG07844.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily RecA PF00154.21 AAG07844.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_33 PF13671.6 AAG07844.1 - 0.17 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAG07844.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase SMC_N PF02463.19 AAG07844.1 - 0.21 11.0 0.1 2.2 7.7 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MobB PF03205.14 AAG07844.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Calici_PP_N PF08405.11 AAG07844.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal SIS PF01380.22 AAG07845.1 - 2.5e-32 111.5 0.1 4e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 AAG07845.1 - 4.3e-14 52.7 6.6 6.5e-07 29.7 0.4 3.9 4 0 0 4 4 4 2 CBS domain SIS_2 PF13580.6 AAG07845.1 - 0.0031 17.5 1.2 0.02 14.9 0.1 2.3 1 1 1 2 2 2 1 SIS domain DisA_N PF02457.16 AAG07845.1 - 0.1 12.2 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding GMP_synt_C PF00958.22 AAG07845.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 GMP synthase C terminal domain Hydrolase_3 PF08282.12 AAG07846.1 - 5e-09 36.3 0.0 1.8e-06 27.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG07846.1 - 5.7e-08 33.3 0.5 8.5e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG07846.1 - 0.00034 21.1 3.2 0.014 15.8 0.1 3.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAG07846.1 - 0.00075 19.6 0.2 0.11 12.5 0.0 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase LptC PF06835.13 AAG07847.1 - 5.6e-52 175.9 0.2 6.9e-52 175.6 0.2 1.0 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related NAGLU_N PF12971.7 AAG07847.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain OstA PF03968.14 AAG07848.1 - 3.2e-26 91.7 4.6 4e-26 91.4 4.6 1.1 1 0 0 1 1 1 1 OstA-like protein LptC PF06835.13 AAG07848.1 - 0.0039 16.8 1.4 0.059 12.9 0.1 2.2 1 1 0 2 2 2 1 Lipopolysaccharide-assembly, LptC-related ABC_tran PF00005.27 AAG07849.1 - 2.2e-33 115.7 0.0 3.8e-33 114.9 0.0 1.4 2 0 0 2 2 2 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAG07849.1 - 3.3e-05 23.7 0.0 7.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 AAG07849.1 - 0.00019 21.0 0.0 0.0018 17.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAG07849.1 - 0.00035 20.5 0.4 0.23 11.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAG07849.1 - 0.054 14.0 0.0 0.097 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAG07849.1 - 0.067 13.6 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 AAG07849.1 - 0.08 13.2 0.0 0.43 10.8 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 AAG07849.1 - 0.092 12.5 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAG07849.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_DBD PF04552.13 AAG07850.1 - 3.5e-72 241.4 0.4 5.5e-72 240.7 0.4 1.3 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 AAG07850.1 - 2e-63 213.5 0.4 5.5e-63 212.0 0.4 1.8 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 AAG07850.1 - 1e-16 60.5 13.3 1e-16 60.5 13.3 2.2 2 0 0 2 2 2 1 Sigma-54 factor, Activator interacting domain (AID) CCDC14 PF15254.6 AAG07850.1 - 0.017 13.8 0.1 0.029 13.1 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Ribosomal_S30AE PF02482.19 AAG07851.1 - 1.2e-28 99.7 2.2 1.3e-28 99.5 2.2 1.0 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein PTS_EIIA_2 PF00359.22 AAG07852.1 - 1e-34 119.5 0.0 1.1e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 AAG07852.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ATP_bind_2 PF03668.15 AAG07853.1 - 9e-95 317.2 0.0 1e-94 317.1 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 AAG07853.1 - 9.7e-06 26.2 0.1 4.7e-05 23.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAG07853.1 - 0.004 17.3 0.2 1.1 9.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 AAG07853.1 - 0.017 15.5 0.3 2.3 8.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 AAG07853.1 - 0.024 15.0 0.3 0.05 14.0 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AAG07853.1 - 0.025 14.5 0.6 0.25 11.2 0.2 2.1 1 1 1 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 AAG07853.1 - 0.028 14.6 0.0 0.31 11.3 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAG07853.1 - 0.04 14.2 0.1 0.11 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 AAG07853.1 - 0.051 13.4 0.1 1.8 8.4 0.0 2.4 3 0 0 3 3 3 0 Deoxynucleoside kinase T2SSE PF00437.20 AAG07853.1 - 0.054 12.5 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 AAG07853.1 - 0.059 12.7 0.3 0.13 11.6 0.3 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 AAG07853.1 - 0.082 12.7 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AAG07853.1 - 0.12 12.9 0.3 0.2 12.2 0.3 1.6 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 AAG07853.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 AAG07853.1 - 0.17 11.2 0.0 0.43 9.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin SKI PF01202.22 AAG07853.1 - 0.26 11.4 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 1 0 Shikimate kinase PTS-HPr PF00381.19 AAG07854.1 - 3.7e-26 91.2 0.1 4.2e-26 91.0 0.1 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site Zip PF02535.22 AAG07855.1 - 3.3e-16 59.4 15.5 3.3e-16 59.4 15.5 2.4 2 1 1 3 3 3 2 ZIP Zinc transporter Ycf66_N PF07444.11 AAG07855.1 - 0.0024 18.0 5.5 0.063 13.4 0.1 3.4 3 0 0 3 3 3 2 Ycf66 protein N-terminus Sod_Fe_C PF02777.18 AAG07856.1 - 2.6e-37 127.1 0.0 4.1e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AAG07856.1 - 3.6e-33 113.9 0.5 5.4e-33 113.3 0.5 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF2753 PF10952.8 AAG07857.1 - 0.0002 21.5 0.2 0.00028 21.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) TPR_2 PF07719.17 AAG07857.1 - 0.0041 17.1 0.2 1.8 8.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAG07857.1 - 0.024 14.8 0.0 2.4 8.6 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAG07857.1 - 0.053 13.8 6.6 3 8.2 0.8 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat Lyase_1 PF00206.20 AAG07858.1 - 4.4e-86 289.1 0.1 5.7e-86 288.7 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AAG07858.1 - 5.9e-20 71.4 0.1 5.9e-20 71.4 0.1 1.8 2 0 0 2 2 2 1 Fumarase C C-terminus PmbA_TldD PF01523.16 AAG07860.1 - 2.6e-62 211.2 0.1 3.5e-62 210.8 0.1 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase DUF615 PF04751.14 AAG07861.1 - 4.6e-55 185.8 2.7 5.5e-55 185.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF615) PmbA_TldD PF01523.16 AAG07862.1 - 9.5e-70 235.6 0.6 1.6e-69 234.8 0.5 1.4 2 0 0 2 2 2 1 Putative modulator of DNA gyrase CN_hydrolase PF00795.22 AAG07863.1 - 5e-50 170.3 0.1 5.6e-50 170.1 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF442 PF04273.13 AAG07863.1 - 0.11 12.6 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Putative phosphatase (DUF442) DUF3875 PF12991.7 AAG07863.1 - 0.16 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) AsmA_2 PF13502.6 AAG07864.1 - 9.8e-53 179.0 3.3 6.5e-51 173.1 0.8 3.5 3 0 0 3 3 3 2 AsmA-like C-terminal region DUF3971 PF13116.6 AAG07864.1 - 1.5e-49 169.1 0.0 2.9e-49 168.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function AsmA PF05170.14 AAG07864.1 - 0.027 13.3 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 AsmA family RNase_E_G PF10150.9 AAG07865.1 - 4.1e-106 354.3 0.6 6e-106 353.8 0.6 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 AAG07865.1 - 1.6e-08 34.7 0.2 6.5e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Maf PF02545.14 AAG07866.1 - 3.9e-54 183.0 0.0 4.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein MreD PF04093.12 AAG07867.1 - 4.2e-40 137.4 18.0 4.7e-40 137.3 18.0 1.0 1 0 0 1 1 1 1 rod shape-determining protein MreD ArAE_1 PF06081.11 AAG07867.1 - 0.034 14.3 1.3 0.048 13.8 0.3 1.7 1 1 1 2 2 2 0 Aromatic acid exporter family member 1 MreC PF04085.14 AAG07868.1 - 6.3e-38 130.0 0.0 9e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 rod shape-determining protein MreC MreB_Mbl PF06723.13 AAG07869.1 - 3.4e-148 492.8 1.4 3.8e-148 492.6 1.4 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 AAG07869.1 - 3.6e-14 51.9 0.5 2.9e-13 48.9 0.1 2.4 1 1 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 AAG07869.1 - 1.3e-11 44.8 0.4 1.1e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 Cell division protein FtsA Actin PF00022.19 AAG07869.1 - 2.6e-11 42.8 0.0 1.5e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 Actin PilM_2 PF11104.8 AAG07869.1 - 1.3e-06 27.7 0.0 0.017 14.1 0.0 2.2 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Ppx-GppA PF02541.16 AAG07869.1 - 0.00011 21.7 1.9 0.0002 20.9 0.5 2.1 2 1 1 3 3 3 1 Ppx/GppA phosphatase family EutA PF06277.11 AAG07869.1 - 0.0069 15.3 1.0 0.021 13.7 0.5 1.9 1 1 1 2 2 2 1 Ethanolamine utilisation protein EutA DDR PF08841.10 AAG07869.1 - 0.0072 15.4 0.5 0.025 13.6 0.2 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 AAG07869.1 - 0.018 14.5 0.4 0.039 13.5 0.1 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 AAG07869.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Glu-tRNAGln PF02686.15 AAG07870.1 - 1.1e-17 64.1 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Amidase PF01425.21 AAG07871.1 - 3.8e-161 537.0 0.0 4.3e-161 536.9 0.0 1.0 1 0 0 1 1 1 1 Amidase GatB_N PF02934.15 AAG07872.1 - 1.2e-111 372.5 0.0 1.8e-111 372.0 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AAG07872.1 - 3.4e-52 176.3 3.0 5.4e-52 175.6 3.0 1.3 1 0 0 1 1 1 1 GatB domain DPBB_1 PF03330.18 AAG07873.1 - 4.6e-28 97.3 0.0 5.8e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Lytic transglycolase HATPase_c_2 PF13581.6 AAG07873.1 - 0.069 13.1 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain CMD PF02627.20 AAG07874.1 - 1.1e-26 92.7 0.9 1.6e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF2135 PF09906.9 AAG07875.1 - 5e-23 81.1 0.6 1.1e-21 76.8 0.2 3.0 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2135) BiPBP_C PF06832.12 AAG07875.1 - 0.079 13.0 0.1 0.52 10.4 0.0 2.3 2 1 1 3 3 3 0 Penicillin-Binding Protein C-terminus Family DUF2300 PF10062.9 AAG07876.1 - 5.1e-82 272.2 17.1 1.5e-43 147.9 1.7 2.8 3 0 0 3 3 3 2 Predicted secreted protein (DUF2300) SpoIID PF08486.10 AAG07876.1 - 5.8e-06 26.8 0.1 9.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Stage II sporulation protein MG2 PF01835.19 AAG07877.1 - 3.1e-25 88.4 1.0 3.5e-19 69.0 0.0 6.4 7 0 0 7 7 7 1 MG2 domain A2M PF00207.22 AAG07877.1 - 5.7e-24 83.8 0.0 1.2e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 AAG07877.1 - 8.4e-14 52.1 0.0 2.7e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain CarboxypepD_reg PF13620.6 AAG07877.1 - 1.9e-07 31.3 2.9 2 8.8 0.0 6.2 6 1 1 7 7 7 2 Carboxypeptidase regulatory-like domain bMG10 PF17973.1 AAG07877.1 - 1.1e-05 25.6 0.0 4.1e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain bMG3 PF11974.8 AAG07877.1 - 1.2e-05 25.3 0.1 0.0071 16.3 0.0 4.6 5 0 0 5 5 5 1 Bacterial alpha-2-macroglobulin MG3 domain Big_1 PF02369.16 AAG07877.1 - 9.9e-05 22.3 0.0 0.67 10.0 0.0 4.5 4 0 0 4 4 4 1 Bacterial Ig-like domain (group 1) DUF4198 PF10670.9 AAG07877.1 - 0.0019 18.6 0.0 7.1 6.9 0.0 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF4198) BiPBP_C PF06832.12 AAG07877.1 - 0.0032 17.5 0.1 2.6 8.2 0.0 4.2 2 1 1 3 3 3 1 Penicillin-Binding Protein C-terminus Family Glyco_hydro_66 PF13199.6 AAG07877.1 - 0.0033 16.1 0.0 1.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 66 MG4 PF17789.1 AAG07877.1 - 0.0048 17.0 0.0 6.3 7.0 0.0 3.5 3 0 0 3 3 3 1 Macroglobulin domain MG4 DUF1175 PF06672.11 AAG07878.1 - 1.8e-77 260.0 0.0 2.1e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1175) NLPC_P60 PF00877.19 AAG07878.1 - 0.00069 19.6 0.2 0.004 17.1 0.2 2.0 1 1 0 1 1 1 1 NlpC/P60 family DUF3987 PF13148.6 AAG07878.1 - 0.11 11.5 0.3 2.2 7.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) DUF2138 PF09909.9 AAG07879.1 - 2.1e-253 841.7 0.0 2.5e-253 841.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2138) DUF2135 PF09906.9 AAG07880.1 - 7.9e-17 61.3 0.8 1.6e-16 60.3 0.8 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2135) Response_reg PF00072.24 AAG07881.1 - 3.5e-22 78.7 0.0 5e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AAG07881.1 - 9.3e-12 44.5 0.6 9.3e-12 44.5 0.6 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 AAG07881.1 - 7.7e-07 28.8 0.8 1.6e-06 27.8 0.8 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAG07881.1 - 0.0015 18.6 0.3 0.0033 17.5 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAG07881.1 - 0.028 14.4 0.1 0.072 13.1 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 AAG07881.1 - 0.054 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HATPase_c PF02518.26 AAG07882.1 - 5.3e-16 59.1 0.0 7.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG07882.1 - 4.9e-07 29.7 1.7 1.1e-06 28.6 1.7 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAG07882.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain DUF1887 PF09002.11 AAG07882.1 - 0.025 13.3 0.7 0.035 12.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) HATPase_c_5 PF14501.6 AAG07882.1 - 0.026 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 GHKL domain HATPase_c_3 PF13589.6 AAG07882.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_20 PF14561.6 AAG07882.1 - 0.24 11.7 4.1 0.52 10.7 1.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_9_N PF15420.6 AAG07882.1 - 2.4 8.1 10.3 10 6.1 10.4 2.0 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SIMPL PF04402.14 AAG07883.1 - 1.5e-26 94.1 1.1 1.8e-26 93.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) SBP_bac_5 PF00496.22 AAG07884.1 - 3e-102 342.4 7.8 3.7e-102 342.1 7.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle RGP PF03214.13 AAG07884.1 - 0.068 12.3 0.0 0.25 10.5 0.0 1.9 3 0 0 3 3 3 0 Reversibly glycosylated polypeptide SBP_bac_5 PF00496.22 AAG07885.1 - 3.4e-98 329.1 0.0 4e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Peptidase_M24 PF00557.24 AAG07886.1 - 4.1e-50 170.4 0.1 1.3e-49 168.8 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.18 AAG07886.1 - 2.3e-23 83.3 0.0 4.3e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain HydF_tetramer PF18133.1 AAG07886.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain P5CR_dimer PF14748.6 AAG07886.1 - 2.3 8.5 7.5 0.16 12.2 0.5 2.5 3 0 0 3 3 3 0 Pyrroline-5-carboxylate reductase dimerisation Cupin_2 PF07883.11 AAG07887.1 - 7.2e-20 70.5 0.1 1.8e-17 62.8 0.0 2.4 3 0 0 3 3 3 1 Cupin domain HTH_31 PF13560.6 AAG07887.1 - 1.6e-08 34.7 0.1 2.5e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG07887.1 - 2.1e-08 34.1 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAG07887.1 - 5.8e-07 29.5 0.2 8.3e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix Cupin_3 PF05899.12 AAG07887.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 AAG07887.1 - 0.00035 20.5 0.1 0.0007 19.5 0.1 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain BetR PF08667.10 AAG07887.1 - 0.042 13.9 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 BetR domain MannoseP_isomer PF01050.18 AAG07887.1 - 0.054 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 AAG07887.1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like HTH_25 PF13413.6 AAG07887.1 - 0.1 12.5 0.4 0.69 9.8 0.4 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 AAG07887.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 AAG07887.1 - 0.17 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain SBP_bac_5 PF00496.22 AAG07888.1 - 3.9e-98 328.9 6.4 4.7e-98 328.6 6.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle OprD PF03573.13 AAG07889.1 - 7.1e-124 413.8 10.6 8.2e-124 413.6 10.6 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family RMI2 PF16100.5 AAG07889.1 - 0.051 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 SBP_bac_5 PF00496.22 AAG07890.1 - 4.1e-96 322.2 0.0 5e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 AAG07891.1 - 1.4e-47 161.8 12.8 2.6e-47 161.0 12.8 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG07892.1 - 9.9e-31 106.9 12.6 9.9e-31 106.9 12.6 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAG07892.1 - 6.4e-15 54.9 0.4 6.4e-15 54.9 0.4 3.3 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 AAG07893.1 - 6.8e-28 97.9 0.0 9.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAG07893.1 - 1.3e-16 60.9 0.5 2.4e-16 60.0 0.5 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAG07893.1 - 2.6e-08 34.1 0.2 1.1e-05 25.4 0.4 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG07893.1 - 1.4e-06 27.9 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG07893.1 - 0.00043 20.6 2.2 0.13 12.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AAG07893.1 - 0.002 17.8 0.2 0.0039 16.9 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAG07893.1 - 0.0035 16.2 0.7 0.015 14.1 0.2 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAG07893.1 - 0.031 14.7 0.4 0.07 13.5 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 AAG07893.1 - 0.032 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 AAG07893.1 - 0.067 13.3 0.3 0.16 12.0 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 AAG07893.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 AAG07893.1 - 0.083 12.6 0.0 9.8 5.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 AAG07893.1 - 0.087 12.5 0.7 0.81 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 AAG07893.1 - 0.1 12.0 0.2 3.3 7.1 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_tran PF00005.27 AAG07894.1 - 1.3e-35 122.9 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAG07894.1 - 2.1e-19 69.8 1.3 4.7e-19 68.7 1.3 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AAG07894.1 - 1e-06 28.4 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG07894.1 - 2.1e-06 28.0 0.7 4.7e-05 23.7 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAG07894.1 - 2.7e-06 27.4 0.0 0.0085 15.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG07894.1 - 0.00024 21.5 0.6 0.00042 20.7 0.6 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAG07894.1 - 0.00033 20.8 0.1 0.001 19.3 0.1 1.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAG07894.1 - 0.0011 18.7 0.1 0.0099 15.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AAG07894.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AAG07894.1 - 0.0052 17.3 0.2 0.0094 16.5 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG07894.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 AAG07894.1 - 0.008 16.1 0.1 0.047 13.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 AAG07894.1 - 0.016 14.6 0.1 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 AAG07894.1 - 0.02 14.3 0.5 1.9 7.9 0.2 2.4 2 1 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 AAG07894.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 AAG07894.1 - 0.051 12.7 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit RNA_helicase PF00910.22 AAG07894.1 - 0.083 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 AAG07894.1 - 0.083 13.3 0.0 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 AAG07894.1 - 0.099 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Methyltransf_32 PF13679.6 AAG07894.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DLIC PF05783.11 AAG07894.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Septin PF00735.18 AAG07894.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin PRK PF00485.18 AAG07894.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 AAG07894.1 - 0.18 11.0 0.0 0.4 9.8 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 AAG07894.1 - 0.19 11.3 0.6 0.45 10.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAG07894.1 - 0.24 11.1 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Tub_N PF16322.5 AAG07894.1 - 0.57 10.5 2.8 0.78 10.1 2.8 1.2 1 0 0 1 1 1 0 Tubby N-terminal LysE PF01810.18 AAG07895.1 - 1.7e-36 125.5 8.5 2e-36 125.2 8.5 1.1 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAG07895.1 - 0.0044 16.7 1.8 0.0044 16.7 1.8 1.6 1 1 0 1 1 1 1 Integral membrane protein TerC family AsnC_trans_reg PF01037.21 AAG07896.1 - 7.1e-23 80.4 0.1 1e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAG07896.1 - 3.7e-19 68.0 0.1 5.3e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAG07896.1 - 3.6e-17 61.9 0.7 5.7e-17 61.3 0.7 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 AAG07896.1 - 2.1e-05 24.5 0.1 4.1e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG07896.1 - 2.1e-05 24.3 0.2 3.8e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAG07896.1 - 0.002 18.0 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAG07896.1 - 0.0056 16.5 0.2 0.0099 15.7 0.2 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG07896.1 - 0.0089 16.0 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_CodY PF08222.11 AAG07896.1 - 0.0098 15.4 0.0 0.026 14.1 0.0 1.7 1 1 1 2 2 2 1 CodY helix-turn-helix domain HTH_5 PF01022.20 AAG07896.1 - 0.021 14.7 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_47 PF16221.5 AAG07896.1 - 0.047 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 winged helix-turn-helix CT_A_B PF02626.15 AAG07897.1 - 3.4e-83 279.3 0.0 3.9e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 AAG07898.1 - 5.4e-67 225.4 0.0 6.4e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D LamB_YcsF PF03746.16 AAG07899.1 - 2.2e-93 312.4 0.0 2.4e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Asp_Arg_Hydrox PF05118.15 AAG07900.1 - 3.2e-48 163.5 0.0 4.4e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 AAG07900.1 - 0.0094 15.6 0.1 0.077 12.7 0.0 2.1 2 0 0 2 2 2 1 Cupin domain PepSY_TM PF03929.16 AAG07901.1 - 5.9e-66 223.1 4.9 8.9e-66 222.5 4.9 1.3 1 0 0 1 1 1 1 PepSY-associated TM region Flavodoxin_1 PF00258.25 AAG07901.1 - 3.2e-25 89.0 0.1 6.4e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 AAG07901.1 - 2.3e-11 44.3 0.0 4.2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PepSY_TM_like_2 PF16357.5 AAG07901.1 - 0.0002 21.4 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 2 Putative PepSY_TM-like Ni_hydr_CYTB PF01292.20 AAG07901.1 - 0.042 13.4 7.1 0.19 11.3 0.2 3.4 3 1 0 3 3 3 0 Prokaryotic cytochrome b561 5TM-5TMR_LYT PF07694.12 AAG07901.1 - 0.052 13.1 0.3 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 5TMR of 5TMR-LYT DUF2627 PF11118.8 AAG07901.1 - 0.079 13.5 0.1 0.079 13.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) FAD_binding_1 PF00667.20 AAG07901.1 - 0.22 11.0 0.0 4.5 6.8 0.0 2.1 1 1 1 2 2 2 0 FAD binding domain DUF2306 PF10067.9 AAG07901.1 - 6 7.1 6.2 7.5 6.7 0.6 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) TonB_dep_Rec PF00593.24 AAG07902.1 - 2.5e-59 202.4 49.7 2.5e-59 202.4 49.7 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG07902.1 - 1.1e-18 67.7 0.6 3e-18 66.4 0.6 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Lipase3_N PF03893.16 AAG07902.1 - 0.051 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Lipase 3 N-terminal region PKHD_C PF18331.1 AAG07903.1 - 6.1e-23 80.6 0.3 1.7e-22 79.2 0.4 1.8 2 0 0 2 2 2 1 PKHD-type hydroxylase C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 AAG07903.1 - 1.2e-12 48.5 0.0 1.7e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 AAG07903.1 - 7e-06 26.5 0.0 1.1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 AAG07903.1 - 0.02 15.2 0.0 3.1 8.0 0.0 2.2 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) IBV_3B PF03622.13 AAG07903.1 - 0.04 14.0 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 IBV 3B protein Sel1 PF08238.12 AAG07904.1 - 2.4e-32 110.6 19.1 6.8e-08 32.9 0.4 6.4 6 0 0 6 6 6 5 Sel1 repeat TetR_C_7 PF14246.6 AAG07904.1 - 0.0041 17.1 7.0 0.012 15.6 0.3 3.2 1 1 2 3 3 3 1 AefR-like transcriptional repressor, C-terminal domain TPR_10 PF13374.6 AAG07904.1 - 0.012 15.5 0.2 0.012 15.5 0.2 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAG07904.1 - 0.018 15.7 0.9 0.018 15.7 0.9 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAG07904.1 - 0.051 13.9 0.1 0.051 13.9 0.1 5.7 5 3 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAG07904.1 - 0.5 11.3 0.2 0.5 11.3 0.2 6.0 2 2 3 6 6 6 0 Tetratricopeptide repeat Sulfatase PF00884.23 AAG07905.1 - 2.5e-49 168.4 3.4 3.2e-49 168.0 3.4 1.1 1 0 0 1 1 1 1 Sulfatase EptA_B_N PF08019.12 AAG07905.1 - 2.5e-06 27.5 2.3 4.2e-06 26.7 2.3 1.3 1 0 0 1 1 1 1 Phosphoethanolamine transferase EptA/EptB Glyoxalase PF00903.25 AAG07906.1 - 1.8e-06 28.2 0.0 2.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG07906.1 - 0.00061 20.6 0.1 0.0019 18.9 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain 3-dmu-9_3-mt PF06983.13 AAG07906.1 - 0.086 13.4 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase Orn_Arg_deC_N PF02784.16 AAG07907.1 - 3.6e-55 187.0 0.0 5.4e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAG07907.1 - 1.8e-11 44.1 0.0 2.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Lipase_GDSL_lke PF16255.5 AAG07907.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MCPsignal PF00015.21 AAG07908.1 - 7.4e-43 146.3 43.6 1.2e-42 145.6 22.1 2.9 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAG07908.1 - 1.4e-09 38.2 2.7 2.3e-07 31.1 0.1 3.9 4 0 0 4 4 4 1 HAMP domain DUF948 PF06103.11 AAG07908.1 - 0.0011 19.2 18.8 0.26 11.6 1.4 6.5 2 1 3 5 5 5 1 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AAG07908.1 - 0.16 12.2 14.2 0.31 11.2 2.9 4.5 3 2 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF5089 PF17002.5 AAG07908.1 - 0.38 10.6 6.3 0.058 13.3 0.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5089) Laminin_II PF06009.12 AAG07908.1 - 1.1 9.3 28.5 2 8.4 3.3 4.7 3 2 2 5 5 5 0 Laminin Domain II Vps53_N PF04100.12 AAG07908.1 - 1.5 7.7 12.6 4.2 6.2 3.3 2.6 2 0 0 2 2 2 0 Vps53-like, N-terminal MCU PF04678.13 AAG07908.1 - 2.1 8.4 7.7 1.6 8.8 0.7 2.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CK2S PF15011.6 AAG07908.1 - 3.3 7.6 17.8 2 8.3 2.7 4.0 4 0 0 4 4 4 0 Casein Kinase 2 substrate AmpE PF17113.5 AAG07909.1 - 2.5e-10 40.2 13.0 3.2e-10 39.8 13.0 1.2 1 0 0 1 1 1 1 Regulatory signalling modulator protein AmpE CobD_Cbib PF03186.13 AAG07909.1 - 0.011 15.0 14.0 0.046 12.9 13.8 2.2 1 1 0 1 1 1 0 CobD/Cbib protein Amidase_2 PF01510.25 AAG07910.1 - 4.5e-27 95.0 0.0 5.5e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase DUF1631 PF07793.11 AAG07911.1 - 1.7e-254 846.8 29.2 1.9e-254 846.6 29.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) QRPTase_C PF01729.19 AAG07912.1 - 1e-56 191.4 0.2 1.5e-56 190.8 0.2 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AAG07912.1 - 7.9e-27 93.1 0.1 1.9e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl_2 PF13533.6 AAG07912.1 - 0.0077 16.0 0.1 0.038 13.8 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like TMP-TENI PF02581.17 AAG07912.1 - 0.016 14.5 0.3 0.47 9.8 0.3 2.3 1 1 0 1 1 1 0 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 AAG07912.1 - 0.12 11.8 0.1 0.36 10.2 0.1 1.8 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family Pilin PF00114.19 AAG07913.1 - 9e-23 81.3 2.8 1.1e-22 81.1 2.8 1.1 1 0 0 1 1 1 1 Pilin (bacterial filament) N_methyl PF07963.12 AAG07913.1 - 1.2e-10 40.5 4.7 1.2e-10 40.5 4.7 1.6 2 0 0 2 2 2 1 Prokaryotic N-terminal methylation motif T2SSE PF00437.20 AAG07914.1 - 2.9e-93 311.9 0.5 4e-93 311.4 0.5 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AAG07914.1 - 3.8e-14 52.9 0.2 1.5e-13 50.9 0.1 2.1 2 1 0 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_22 PF13401.6 AAG07914.1 - 0.0015 18.8 0.0 0.0044 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG07914.1 - 0.0025 17.6 0.5 0.0085 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAG07914.1 - 0.0078 16.6 0.1 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 AAG07914.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAG07914.1 - 0.072 12.8 0.1 0.24 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 AAG07914.1 - 0.12 11.8 0.1 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DiS_P_DiS PF06750.13 AAG07916.1 - 4.5e-34 116.4 0.1 2e-33 114.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 AAG07916.1 - 2e-24 86.1 16.1 2e-24 86.1 16.1 2.0 2 0 0 2 2 2 1 Type IV leader peptidase family DUF1427 PF07235.11 AAG07916.1 - 0.24 11.4 2.8 3.4 7.7 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1427) zf_UBZ PF18439.1 AAG07916.1 - 0.6 9.7 2.1 0.77 9.4 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 AAG07916.1 - 0.83 9.1 3.4 3.7 7.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AAG07916.1 - 0.96 9.2 3.3 1.2 9.0 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain CoaE PF01121.20 AAG07917.1 - 1.2e-68 230.3 0.0 1.4e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 AAG07917.1 - 0.0054 16.9 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAG07917.1 - 0.082 13.1 0.3 2.7 8.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAG07917.1 - 0.21 12.1 1.4 2.8 8.5 0.3 2.5 1 1 1 2 2 2 0 AAA domain YacG PF03884.14 AAG07918.1 - 1.5e-26 91.8 0.9 1.7e-26 91.7 0.9 1.1 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG Nudix_N_2 PF14803.6 AAG07918.1 - 0.00062 19.6 1.2 0.001 18.9 0.5 1.7 2 0 0 2 2 2 1 Nudix N-terminal zf-ribbon_3 PF13248.6 AAG07918.1 - 0.0073 15.7 0.1 0.015 14.6 0.1 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Lar_restr_allev PF14354.6 AAG07918.1 - 0.048 14.0 0.6 0.067 13.6 0.6 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-HIT PF04438.16 AAG07918.1 - 0.064 13.1 1.3 0.096 12.6 1.3 1.3 1 0 0 1 1 1 0 HIT zinc finger DUF2116 PF09889.9 AAG07918.1 - 0.1 12.6 0.6 0.19 11.7 0.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2256 PF10013.9 AAG07918.1 - 0.26 11.4 5.9 8.5 6.6 5.9 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) CbiM PF01891.16 AAG07920.1 - 4.1e-16 59.4 13.4 5e-16 59.2 13.4 1.0 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region CbtB PF09489.10 AAG07920.1 - 0.42 10.8 7.7 6 7.1 0.2 3.5 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtB) Acetyltransf_1 PF00583.25 AAG07922.1 - 1.3e-11 44.7 0.0 1.7e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG07922.1 - 3.9e-08 33.3 0.0 5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG07922.1 - 1.3e-07 32.0 0.0 1.7e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAG07922.1 - 8.3e-06 26.0 1.0 8.3e-06 26.0 1.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG07922.1 - 0.0011 19.1 0.0 0.0021 18.1 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAG07922.1 - 0.004 17.2 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG07922.1 - 0.0047 16.9 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PaaB PF06243.11 AAG07922.1 - 0.11 12.8 0.0 0.51 10.6 0.1 1.9 2 0 0 2 2 2 0 Phenylacetic acid degradation B Acetyltransf_15 PF17013.5 AAG07922.1 - 0.25 10.8 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase DUF1780 PF08682.10 AAG07923.1 - 2.9e-131 435.4 2.8 3.2e-131 435.3 2.8 1.0 1 0 0 1 1 1 1 Putative endonuclease, protein of unknown function (DUF1780) MOSC PF03473.17 AAG07924.1 - 2.7e-06 27.4 0.0 4.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 MOSC domain DUF3094 PF11293.8 AAG07925.1 - 1.6e-35 120.6 1.3 1.7e-35 120.5 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3094) TraB PF01963.17 AAG07925.1 - 0.025 14.5 0.0 0.027 14.4 0.0 1.0 1 0 0 1 1 1 0 TraB family DUF5336 PF17270.2 AAG07925.1 - 0.057 13.1 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5336) HXXSHH PF07586.11 AAG07925.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Pyr_redox_2 PF07992.14 AAG07926.1 - 1e-60 205.5 0.1 1.2e-60 205.3 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG07926.1 - 1.3e-16 60.9 0.7 1.1e-10 42.0 0.0 2.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAG07926.1 - 1.3e-05 25.2 2.4 0.057 13.4 0.1 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAG07926.1 - 3.6e-05 23.0 1.0 0.029 13.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 AAG07926.1 - 0.00044 19.9 8.8 0.63 9.5 1.6 3.9 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG07926.1 - 0.0016 18.6 5.8 0.089 13.0 0.6 2.9 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 AAG07926.1 - 0.0066 16.1 0.4 0.5 10.0 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 AAG07926.1 - 0.0075 15.6 1.5 2.2 7.6 0.0 2.4 2 0 0 2 2 2 2 ThiF family K_oxygenase PF13434.6 AAG07926.1 - 0.01 15.0 0.4 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 AAG07926.1 - 0.016 15.5 0.2 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Amidase_2 PF01510.25 AAG07926.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Pyr_redox_3 PF13738.6 AAG07926.1 - 0.038 13.2 0.6 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG07926.1 - 0.15 10.7 2.9 1.8 7.2 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 AAG07926.1 - 0.23 10.3 2.3 0.35 9.7 0.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 AAG07926.1 - 0.91 8.7 5.3 9.4 5.4 0.6 2.4 2 0 0 2 2 2 0 FAD binding domain AFG1_ATPase PF03969.16 AAG07927.1 - 6.5e-137 456.2 0.0 8.2e-137 455.9 0.0 1.1 1 0 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 AAG07927.1 - 0.035 14.5 0.1 0.44 10.9 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 AAG07927.1 - 0.04 14.2 0.0 0.093 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAG07927.1 - 0.043 13.6 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ShlB PF03865.13 AAG07928.1 - 1.5e-25 90.3 4.7 1.9e-25 89.9 4.7 1.1 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AAG07928.1 - 1.2e-22 79.6 0.0 2.2e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 POTRA domain, ShlB-type POTRA PF07244.15 AAG07928.1 - 1.1e-05 25.9 0.0 6.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Surface antigen variable number repeat Glug PF07581.12 AAG07929.1 - 9.8e-46 151.2 146.2 1.9e-05 24.8 2.2 21.3 20 0 0 20 20 20 17 The GLUG motif Haemagg_act PF05860.13 AAG07929.1 - 4.1e-28 97.7 0.4 4.1e-28 97.7 0.4 4.3 4 1 0 4 4 4 1 haemagglutination activity domain ESPR PF13018.6 AAG07929.1 - 1.2e-08 34.6 0.2 2.4e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 Extended Signal Peptide of Type V secretion system AAA_2 PF07724.14 AAG07930.1 - 1.2e-58 198.0 0.0 1.3e-55 188.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAG07930.1 - 6.8e-37 125.6 4.4 6.8e-37 125.6 4.4 2.8 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 AAG07930.1 - 2.6e-25 88.3 2.8 3.2e-25 88.0 0.2 2.7 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AAG07930.1 - 2.9e-24 86.0 0.1 5.3e-12 46.3 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 AAG07930.1 - 3.3e-24 84.8 5.1 1.3e-12 47.6 0.2 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 AAG07930.1 - 2.6e-19 69.6 0.1 9.1e-14 51.6 0.0 3.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAG07930.1 - 4.1e-10 40.3 11.0 4.4e-05 23.9 0.0 5.2 4 2 0 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 AAG07930.1 - 5.6e-09 36.4 2.8 0.012 15.9 0.0 5.0 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 AAG07930.1 - 6.5e-08 32.5 0.4 0.12 12.1 0.0 4.1 3 1 0 3 3 3 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 AAG07930.1 - 7.7e-08 32.2 0.0 6.4e-05 22.7 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 AAG07930.1 - 6.3e-07 29.0 0.0 0.00064 19.2 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 AAG07930.1 - 2.9e-06 27.8 0.3 0.046 14.3 0.1 3.9 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 AAG07930.1 - 9.7e-06 25.4 0.0 0.011 15.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 AAG07930.1 - 1.6e-05 24.4 0.0 0.23 10.8 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 AAG07930.1 - 3.2e-05 24.0 5.0 0.73 9.7 0.0 4.8 3 2 2 5 5 5 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AAG07930.1 - 5.3e-05 23.2 0.0 0.54 10.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 AAG07930.1 - 6e-05 22.8 0.5 4.6 7.0 0.2 4.4 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AAG07930.1 - 8e-05 22.2 0.0 0.19 11.2 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region DUF815 PF05673.13 AAG07930.1 - 0.0002 20.6 0.0 0.24 10.5 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF815) ABC_tran PF00005.27 AAG07930.1 - 0.00032 21.2 5.2 0.54 10.8 0.0 4.4 3 1 0 3 3 3 1 ABC transporter AAA_19 PF13245.6 AAG07930.1 - 0.00034 21.0 0.0 0.097 13.0 0.1 3.4 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 AAG07930.1 - 0.00037 20.4 0.0 1.1 9.1 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 AAG07930.1 - 0.00045 20.4 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DNA_pol3_delta2 PF13177.6 AAG07930.1 - 0.0005 19.9 0.0 1.3 8.8 0.0 2.8 2 0 0 2 2 2 2 DNA polymerase III, delta subunit RNA_helicase PF00910.22 AAG07930.1 - 0.00054 20.3 0.0 1.4 9.3 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_3 PF07726.11 AAG07930.1 - 0.00089 19.1 0.1 0.62 9.9 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 AAG07930.1 - 0.001 19.1 0.0 2.1 8.4 0.0 2.9 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 AAG07930.1 - 0.0029 17.5 0.0 0.31 10.9 0.0 2.9 2 1 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 AAG07930.1 - 0.003 17.8 5.1 4.2 7.6 0.0 4.7 4 1 1 5 5 4 1 AAA domain AAA_29 PF13555.6 AAG07930.1 - 0.0049 16.6 0.0 2.9 7.7 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 AAG07930.1 - 0.012 15.4 0.5 0.76 9.5 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 AAG07930.1 - 0.013 15.7 0.2 14 5.9 0.1 3.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AAG07930.1 - 0.013 15.4 0.1 9.8 6.0 0.0 3.5 4 0 0 4 4 2 0 NTPase AAA_25 PF13481.6 AAG07930.1 - 0.014 15.0 3.6 0.95 9.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain ResIII PF04851.15 AAG07930.1 - 0.023 14.7 0.0 9.6 6.2 0.0 3.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 AAG07930.1 - 0.04 13.7 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 AAG07930.1 - 0.051 13.2 0.0 2.6 7.6 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 AAG07930.1 - 0.058 13.9 21.6 0.86 10.1 0.0 4.1 3 1 0 3 3 2 0 AAA domain Atg14 PF10186.9 AAG07930.1 - 3.5 6.6 11.4 7.1 5.6 11.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 AAG07930.1 - 5.7 4.7 5.4 7.5 4.3 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cu-oxidase_4 PF02578.15 AAG07931.1 - 2.9e-76 256.1 0.0 3.3e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase PseudoU_synth_2 PF00849.22 AAG07932.1 - 2.1e-32 112.4 0.3 2.8e-32 112.0 0.3 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAG07932.1 - 2e-07 30.6 0.4 4.8e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 S4 domain TruB_N PF01509.18 AAG07932.1 - 0.047 14.0 0.2 0.12 12.8 0.1 1.6 1 1 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) YfiO PF13525.6 AAG07933.1 - 1.6e-80 269.6 8.2 2.5e-80 269.0 8.2 1.3 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.6 AAG07933.1 - 9.3e-52 175.0 5.8 1.8e-51 174.0 5.8 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAG07933.1 - 3.6e-06 27.2 10.3 0.11 13.2 0.4 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 AAG07933.1 - 5.6e-05 22.9 1.9 0.00012 21.9 0.9 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 AAG07933.1 - 0.0044 17.6 12.0 0.019 15.6 1.9 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAG07933.1 - 0.3 12.0 8.5 1.6 9.8 0.5 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat HATPase_c PF02518.26 AAG07934.1 - 2.1e-18 66.9 0.0 4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG07934.1 - 7e-15 54.8 1.6 7e-15 54.8 1.6 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAG07934.1 - 0.0024 17.9 0.0 0.0078 16.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAG07934.1 - 0.035 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PAS PF00989.25 AAG07934.1 - 0.036 14.0 0.2 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 PAS fold PAS_7 PF12860.7 AAG07934.1 - 0.074 13.2 0.4 0.42 10.8 0.0 2.3 2 0 0 2 2 2 0 PAS fold HATPase_c_3 PF13589.6 AAG07934.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sigma54_activat PF00158.26 AAG07935.1 - 3.6e-67 225.3 0.0 5.5e-67 224.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAG07935.1 - 1e-29 103.0 0.0 2.5e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAG07935.1 - 1.6e-28 99.6 0.0 5.8e-28 97.7 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG07935.1 - 2.5e-16 59.2 2.9 2.5e-16 59.2 2.9 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 AAG07935.1 - 1.2e-05 24.8 0.1 2.7e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_5 PF07728.14 AAG07935.1 - 0.00027 21.0 0.0 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAG07935.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 AAG07935.1 - 0.07 12.9 0.1 0.07 12.9 0.1 2.4 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Mg_chelatase PF01078.21 AAG07935.1 - 0.13 11.6 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AAG07935.1 - 0.63 10.4 4.6 0.69 10.3 1.7 2.7 2 1 0 2 2 2 0 AAA ATPase domain DAO PF01266.24 AAG07936.1 - 2.6e-69 234.5 3.2 2.9e-69 234.3 3.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG07936.1 - 1.4e-12 47.4 0.7 2.2e-12 46.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAG07936.1 - 6.6e-08 31.7 1.4 0.0011 17.8 1.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 AAG07936.1 - 6.8e-07 28.8 2.5 8e-05 22.0 2.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAG07936.1 - 1.1e-06 28.1 0.6 0.00012 21.4 0.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG07936.1 - 3.5e-05 24.3 1.6 0.00025 21.6 1.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG07936.1 - 3.7e-05 23.9 0.1 7.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AAG07936.1 - 4.6e-05 22.8 0.0 0.075 12.3 0.2 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG07936.1 - 0.00033 20.0 1.1 0.0009 18.5 1.2 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 AAG07936.1 - 0.00096 19.2 1.9 0.26 11.3 0.1 2.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 AAG07936.1 - 0.0013 17.9 0.4 1.7 7.6 1.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A ApbA PF02558.16 AAG07936.1 - 0.0036 16.9 1.4 0.0064 16.2 1.4 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 AAG07936.1 - 0.0038 16.6 0.6 0.011 15.1 0.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAG07936.1 - 0.0044 16.9 0.4 0.007 16.3 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AAG07936.1 - 0.011 14.8 0.7 0.02 14.0 0.7 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.21 AAG07936.1 - 0.042 13.2 0.6 0.065 12.6 0.6 1.2 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.14 AAG07936.1 - 0.044 13.3 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 AAG07936.1 - 0.06 12.6 1.3 1.3 8.2 0.6 2.1 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 AAG07936.1 - 0.071 13.6 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 AAG07936.1 - 0.3 10.5 0.3 0.53 9.7 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GspH PF12019.8 AAG07937.1 - 1.8e-14 54.0 0.1 2.6e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AAG07937.1 - 9.2e-05 21.8 2.0 0.00015 21.2 2.0 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif GspH PF12019.8 AAG07938.1 - 8.9e-13 48.6 0.2 1.2e-12 48.2 0.2 1.1 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AAG07938.1 - 3.4e-06 26.4 3.3 3.4e-06 26.4 3.3 1.7 2 0 0 2 2 2 1 Prokaryotic N-terminal methylation motif Baculo_gp41 PF04700.12 AAG07938.1 - 0.061 13.1 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Invasin_D3 PF09134.10 AAG07938.1 - 0.066 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Invasin, domain 3 DUF2547 PF10818.8 AAG07938.1 - 0.11 13.4 0.3 0.2 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) N_methyl PF07963.12 AAG07939.1 - 2.2e-06 27.0 3.3 3.4e-06 26.4 3.3 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DUF962 PF06127.11 AAG07939.1 - 0.028 14.5 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF962) N_methyl PF07963.12 AAG07940.1 - 9.9e-07 28.1 1.4 2e-06 27.1 1.4 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif PilW PF16074.5 AAG07940.1 - 3.7e-06 27.0 0.0 1e-05 25.6 0.0 1.7 1 1 1 2 2 2 1 Type IV Pilus-assembly protein W PilX_N PF14341.6 AAG07941.1 - 4.8e-10 39.2 3.8 5.9e-10 39.0 2.6 1.8 2 0 0 2 2 2 1 PilX N-terminal Tad PF13400.6 AAG07941.1 - 5 7.5 8.3 91 3.5 8.3 2.4 1 1 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Neisseria_PilC PF05567.11 AAG07942.1 - 8.6e-224 742.3 4.1 1.7e-223 741.4 4.1 1.5 1 0 0 1 1 1 1 Neisseria PilC beta-propeller domain Fimbrial_PilY2 PF14481.6 AAG07943.1 - 6.6e-54 180.0 0.0 7.4e-54 179.8 0.0 1.0 1 0 0 1 1 1 1 Type 4 fimbrial biogenesis protein PilY2 Caf4 PF11615.8 AAG07943.1 - 0.11 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 CCR4-associated factor 4 HTH_37 PF13744.6 AAG07943.1 - 0.13 12.2 0.2 0.18 11.8 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain ComP_DUS PF16732.5 AAG07944.1 - 1.5e-25 89.8 2.7 2e-25 89.5 2.7 1.1 1 0 0 1 1 1 1 Type IV minor pilin ComP, DNA uptake sequence receptor N_methyl PF07963.12 AAG07944.1 - 2.7e-09 36.2 2.5 4e-09 35.6 2.5 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif LYTB PF02401.18 AAG07945.1 - 4.2e-92 308.1 0.0 4.8e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 LytB protein ELFV_dehydrog_N PF02812.18 AAG07945.1 - 0.02 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FKBP_C PF00254.28 AAG07946.1 - 8.2e-24 83.8 0.0 1.4e-23 83.0 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Peptidase_A8 PF01252.18 AAG07947.1 - 9e-40 136.2 8.3 1e-39 136.0 8.3 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II ECF_trnsprt PF12822.7 AAG07947.1 - 0.045 13.9 4.6 0.025 14.7 2.8 1.5 1 1 1 2 2 2 0 ECF transporter, substrate-specific component Sec62 PF03839.16 AAG07947.1 - 0.72 9.3 5.0 0.95 8.9 5.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF983 PF06170.12 AAG07947.1 - 5.2 7.6 6.9 9 6.8 1.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF983) tRNA-synt_1 PF00133.22 AAG07948.1 - 3.7e-197 656.3 0.0 4.5e-197 656.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAG07948.1 - 6.5e-28 97.6 0.5 1.4e-27 96.5 0.1 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AAG07948.1 - 4.9e-22 78.2 0.0 3.6e-12 45.7 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AAG07948.1 - 1.3e-08 34.5 0.0 6.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 AAG07948.1 - 3e-08 33.4 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 AAG07948.1 - 1.7e-07 31.0 3.9 1.7e-07 31.0 3.9 2.0 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1f PF01921.18 AAG07948.1 - 0.00077 18.5 0.0 0.0022 17.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) FAD_syn PF06574.12 AAG07949.1 - 1.5e-54 184.2 0.0 1.9e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 AAG07949.1 - 9.9e-37 125.7 0.0 1.5e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 AAG07949.1 - 0.019 15.2 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 Cytidylyltransferase-like MurJ PF03023.14 AAG07950.1 - 8.4e-155 515.8 29.4 1.1e-154 515.4 29.4 1.0 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 AAG07950.1 - 2e-09 37.7 17.9 2e-09 37.7 17.9 3.7 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain ATP1G1_PLM_MAT8 PF02038.16 AAG07950.1 - 0.11 11.9 0.4 0.53 9.8 0.4 2.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family MatE PF01554.18 AAG07950.1 - 1 9.0 27.5 0.16 11.7 3.5 3.1 3 1 0 3 3 3 0 MatE Holin_SPP1 PF04688.13 AAG07950.1 - 8.3 6.7 7.4 8.2 6.7 1.3 3.1 2 0 0 2 2 2 0 SPP1 phage holin Ribosomal_S20p PF01649.18 AAG07951.1 - 7.5e-29 100.2 11.4 8.5e-29 100.0 11.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 SPK PF04435.18 AAG07951.1 - 0.078 13.4 0.1 0.087 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF545) CreA PF05981.12 AAG07952.1 - 2.5e-59 198.9 0.0 2.9e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 CreA protein DUF4136 PF13590.6 AAG07952.1 - 0.14 12.8 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) AA_kinase PF00696.28 AAG07953.1 - 3e-47 161.2 1.2 5.9e-47 160.3 0.7 1.7 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 AAG07953.1 - 4.4e-23 81.0 0.2 9.9e-23 79.9 0.2 1.7 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 AAG07953.1 - 0.012 15.4 0.1 0.054 13.3 0.0 2.1 2 0 0 2 2 2 0 PUA-like domain GTP1_OBG PF01018.22 AAG07954.1 - 1.6e-60 203.2 3.1 2.1e-60 202.8 3.1 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 AAG07954.1 - 9.6e-22 77.2 0.0 1.6e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAG07954.1 - 8e-08 32.0 0.0 2.3e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 AAG07954.1 - 0.002 17.2 0.1 1.4 7.8 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 AAG07954.1 - 0.018 15.6 0.1 1.2 9.7 0.0 2.6 1 1 1 2 2 2 0 AAA domain Sec16 PF12932.7 AAG07954.1 - 0.14 12.8 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Ribosomal_L27 PF01016.19 AAG07955.1 - 4.7e-38 129.1 4.3 5.3e-38 128.9 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_L21p PF00829.21 AAG07956.1 - 5.4e-40 135.7 3.3 5.9e-40 135.6 3.3 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein polyprenyl_synt PF00348.17 AAG07957.1 - 6e-71 238.5 0.0 7e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 AAG07957.1 - 0.0042 16.6 0.5 0.0066 16.0 0.5 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Cytochrom_C PF00034.21 AAG07959.1 - 1.9e-28 99.4 1.2 8.8e-06 26.8 0.0 6.0 5 1 0 5 5 5 4 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG07959.1 - 1.9e-27 95.4 1.3 1.2e-06 28.7 0.0 5.9 5 1 0 5 5 5 5 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 AAG07959.1 - 8e-06 25.5 9.5 1.8 8.4 0.0 5.3 5 0 0 5 5 5 4 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 AAG07959.1 - 0.045 14.2 4.6 46 4.6 0.0 4.8 5 0 0 5 5 5 0 Cytochrome c3 Cytochrom_C550 PF14495.6 AAG07959.1 - 0.091 12.5 0.8 42 3.8 0.0 4.5 5 0 0 5 5 5 0 Cytochrome c-550 domain PSCyt1 PF07635.11 AAG07959.1 - 8.6 7.0 0.0 8.6 7.0 0.0 4.6 5 0 0 5 5 5 0 Planctomycete cytochrome C FKBP_C PF00254.28 AAG07960.1 - 2.2e-26 92.0 0.0 3.9e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AAG07960.1 - 3.8e-21 75.8 0.0 5e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Mito_carr PF00153.27 AAG07960.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein DUF3005 PF11448.8 AAG07960.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) UPF0114 PF03350.16 AAG07962.1 - 3e-35 121.0 5.6 4.4e-35 120.4 5.6 1.3 1 0 0 1 1 1 1 Uncharacterized protein family, UPF0114 AMO PF02461.16 AAG07963.1 - 0.091 12.5 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Ammonia monooxygenase AAA_32 PF13654.6 AAG07964.1 - 1.4e-179 598.2 0.0 1.7e-179 597.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 AAG07964.1 - 6.9e-08 32.3 0.0 1.5e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_5 PF07728.14 AAG07964.1 - 0.022 14.7 0.0 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG07964.1 - 0.033 13.6 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AAG07964.1 - 0.16 12.4 1.7 0.49 10.8 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain zf-dskA_traR PF01258.17 AAG07965.1 - 1.8e-09 37.3 6.8 1.8e-09 37.3 6.8 1.6 1 1 1 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger DUF3015 PF11220.8 AAG07966.1 - 4.4e-56 188.7 2.1 5e-56 188.5 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3015) DUF4105 PF13387.6 AAG07967.1 - 5.5e-61 205.1 0.0 9.4e-61 204.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) DUF1768 PF08719.11 AAG07968.1 - 9e-53 178.8 0.0 1e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RtcR PF06956.11 AAG07969.1 - 1.9e-86 288.2 0.0 2.7e-86 287.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of RNA terminal phosphate cyclase Sigma54_activat PF00158.26 AAG07969.1 - 7e-50 169.0 0.1 1.2e-49 168.3 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG07969.1 - 2.2e-15 57.0 0.0 3.4e-14 53.1 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 AAG07969.1 - 3.1e-08 34.1 0.0 6.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAG07969.1 - 4.1e-07 29.6 0.0 0.016 14.6 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAG07969.1 - 7.1e-07 29.3 0.0 2.3e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAG07969.1 - 8.8e-05 22.8 0.0 0.00021 21.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG07969.1 - 0.00084 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG07969.1 - 0.00089 19.7 2.3 0.0017 18.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 AAG07969.1 - 0.0024 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MCM PF00493.23 AAG07969.1 - 0.004 16.3 0.0 0.0083 15.3 0.0 1.5 1 1 0 1 1 1 1 MCM P-loop domain TniB PF05621.11 AAG07969.1 - 0.0052 16.2 0.0 0.018 14.5 0.0 1.8 1 1 0 1 1 1 1 Bacterial TniB protein T2SSE PF00437.20 AAG07969.1 - 0.0075 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 AAG07969.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 AAG07969.1 - 0.018 15.2 0.0 0.075 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAG07969.1 - 0.02 14.6 0.0 0.064 13.0 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 AAG07969.1 - 0.025 15.1 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 AAG07969.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AAG07969.1 - 0.037 14.1 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AAG07969.1 - 0.043 13.9 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Band_7 PF01145.25 AAG07970.1 - 7.7e-25 87.9 0.1 4.7e-22 78.8 0.4 2.5 3 0 0 3 3 3 2 SPFH domain / Band 7 family Band_7_1 PF13421.6 AAG07970.1 - 0.16 11.6 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 SPFH domain-Band 7 family RtcB PF01139.17 AAG07971.1 - 5.6e-134 447.4 0.7 7.5e-134 447.0 0.7 1.2 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB RlaP PF10127.9 AAG07972.1 - 4.4e-92 308.1 0.2 4.9e-92 307.9 0.2 1.0 1 0 0 1 1 1 1 RNA repair pathway DNA polymerase beta family Polbeta PF18765.1 AAG07972.1 - 0.013 15.5 0.0 0.029 14.5 0.0 1.6 1 1 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase RTC PF01137.21 AAG07973.1 - 1.4e-77 259.8 0.0 1.7e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 AAG07973.1 - 5.8e-09 36.4 0.1 1e-08 35.6 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CCP_MauG PF03150.14 AAG07975.1 - 5.9e-53 179.5 0.0 5.8e-51 173.1 0.0 2.2 2 0 0 2 2 2 1 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.21 AAG07975.1 - 4.4e-15 56.6 0.0 9.8e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG07975.1 - 0.00012 22.3 2.7 0.57 10.5 0.1 3.2 2 1 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 AAG07975.1 - 0.018 15.0 0.0 7.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_C550 PF14495.6 AAG07975.1 - 0.15 11.8 0.1 20 4.9 0.0 2.6 2 0 0 2 2 2 0 Cytochrome c-550 domain Paired_CXXCH_1 PF09699.10 AAG07975.1 - 0.18 11.6 1.5 9.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) ELFV_dehydrog PF00208.21 AAG07976.1 - 3.7e-86 288.8 0.1 4.6e-86 288.5 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AAG07976.1 - 2.9e-50 169.5 0.0 4.8e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 AAG07976.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Toluene_X PF03349.16 AAG07977.1 - 5.6e-160 532.7 6.3 6.3e-160 532.5 6.3 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) TonB_dep_Rec PF00593.24 AAG07977.1 - 2.2e-07 31.1 20.8 4.6e-06 26.8 8.6 2.1 1 1 1 2 2 2 2 TonB dependent receptor BBP2 PF07642.11 AAG07977.1 - 0.00013 21.2 1.3 0.00013 21.2 1.3 2.5 1 1 0 2 2 2 1 Putative beta-barrel porin-2, OmpL-like. bbp2 MtrB_PioB PF11854.8 AAG07977.1 - 0.00023 19.6 0.3 0.0007 18.1 0.3 1.8 2 0 0 2 2 2 1 Putative outer membrane beta-barrel porin, MtrB/PioB MipA PF06629.12 AAG07977.1 - 0.00027 21.3 2.3 0.089 13.0 0.0 3.3 1 1 1 3 3 3 2 MltA-interacting protein MipA Autotransporter PF03797.19 AAG07977.1 - 0.00043 20.0 1.3 0.00043 20.0 1.3 4.3 3 1 1 5 5 5 1 Autotransporter beta-domain YadA_anchor PF03895.15 AAG07977.1 - 0.0013 18.8 0.9 0.012 15.7 0.2 3.1 2 1 0 2 2 2 1 YadA-like membrane anchor domain DUF2490 PF10677.9 AAG07977.1 - 0.0018 18.2 0.9 0.33 10.9 0.4 3.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2490) DUF481 PF04338.12 AAG07977.1 - 0.0088 16.1 1.1 0.57 10.2 0.4 3.0 2 1 0 2 2 2 1 Protein of unknown function, DUF481 OMP_b-brl PF13505.6 AAG07977.1 - 0.012 15.8 1.7 0.012 15.8 1.7 3.9 1 1 0 2 2 2 0 Outer membrane protein beta-barrel domain Opacity PF02462.15 AAG07977.1 - 0.11 12.5 0.6 7.7 6.6 0.0 3.1 3 1 1 4 4 4 0 Opacity family porin protein HlyD_3 PF13437.6 AAG07979.1 - 1.7e-15 57.6 1.9 1.9e-09 38.1 0.1 3.7 2 1 1 4 4 4 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAG07979.1 - 6.2e-14 51.7 7.7 1.8e-11 43.7 6.3 3.3 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAG07979.1 - 1.4e-09 37.6 0.1 1.4e-09 37.6 0.1 3.2 4 0 0 4 4 4 1 Biotin-lipoyl like HlyD PF00529.20 AAG07979.1 - 8.5e-05 22.4 0.0 0.001 18.9 0.0 2.2 1 1 1 2 2 2 1 HlyD membrane-fusion protein of T1SS OEP PF02321.18 AAG07979.1 - 0.016 15.0 6.4 0.016 15.0 6.4 2.9 3 0 0 3 3 3 0 Outer membrane efflux protein Biotin_lipoyl PF00364.22 AAG07979.1 - 0.017 15.0 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme PepSY_2 PF13670.6 AAG07979.1 - 0.16 12.0 1.7 13 5.8 0.0 2.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain COG2 PF06148.11 AAG07979.1 - 8 6.6 6.2 4.6 7.3 0.8 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OEP PF02321.18 AAG07980.1 - 9.5e-42 142.9 36.0 5.1e-23 81.9 14.8 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein MacB_PCD PF12704.7 AAG07981.1 - 7.8e-22 78.6 0.3 7.8e-22 78.6 0.3 1.6 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AAG07981.1 - 3e-10 40.4 1.3 3e-10 40.4 1.3 2.9 3 0 0 3 3 3 1 FtsX-like permease family YopD PF05844.12 AAG07981.1 - 0.065 12.2 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 YopD protein Tecti-min-caps PF09300.10 AAG07981.1 - 0.16 12.0 0.7 0.58 10.2 0.1 2.1 2 0 0 2 2 2 0 Tectiviridae, minor capsid ABC_tran PF00005.27 AAG07982.1 - 1.6e-29 103.2 0.0 2.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG07982.1 - 2.9e-09 37.2 0.6 0.0021 17.9 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG07982.1 - 6.5e-05 22.5 0.0 0.08 12.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAG07982.1 - 0.00041 20.0 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG07982.1 - 0.00052 20.3 0.5 0.014 15.7 0.5 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AAG07982.1 - 0.0012 18.8 0.0 0.57 10.1 0.0 2.3 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 AAG07982.1 - 0.0024 18.3 0.8 0.0049 17.3 0.8 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG07982.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAG07982.1 - 0.013 15.6 0.0 0.034 14.2 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 AAG07982.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AAG07982.1 - 0.021 14.2 0.2 0.051 12.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 AAG07982.1 - 0.04 13.5 0.1 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAG07982.1 - 0.064 13.5 0.1 0.17 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 AAG07982.1 - 0.081 13.4 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 AAG07982.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_15 PF13175.6 AAG07982.1 - 0.11 12.2 0.0 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 AAG07982.1 - 0.11 12.6 0.3 0.33 11.1 0.3 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAG07983.1 - 6.6e-54 182.1 0.0 4.2e-28 98.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AAG07983.1 - 7.6e-15 54.7 6.3 7.4e-11 41.9 4.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAG07983.1 - 7.1e-13 49.0 8.1 0.00096 19.0 0.1 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 AAG07983.1 - 1.2e-06 28.5 0.3 0.017 15.2 0.2 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 AAG07983.1 - 2.8e-06 26.9 3.0 2.5 7.5 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG07983.1 - 5.3e-05 23.8 3.4 0.16 12.5 0.0 3.4 3 1 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 AAG07983.1 - 0.00037 20.6 1.0 0.027 14.5 0.0 2.9 3 1 0 3 3 3 1 Dynamin family MeaB PF03308.16 AAG07983.1 - 0.00044 19.3 0.7 0.53 9.2 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 AAG07983.1 - 0.00053 19.7 3.3 0.18 11.6 0.3 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG07983.1 - 0.00075 19.8 0.1 0.38 11.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAG07983.1 - 0.0011 19.0 0.4 0.32 10.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 AAG07983.1 - 0.0049 17.1 0.7 2.9 8.2 0.0 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 AAG07983.1 - 0.01 16.1 1.4 0.82 9.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 AAG07983.1 - 0.012 15.1 0.1 0.85 9.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 AAG07983.1 - 0.016 15.8 0.6 9.2 6.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAG07983.1 - 0.017 14.8 0.0 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 AAG07983.1 - 0.021 13.6 0.6 1.9 7.2 0.1 2.4 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) AAA_27 PF13514.6 AAG07983.1 - 0.034 13.7 0.1 12 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 AAG07983.1 - 0.039 13.5 0.5 3.1 7.3 0.1 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B Peptidase_C58 PF03543.14 AAG07983.1 - 0.04 13.6 0.8 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Roc PF08477.13 AAG07983.1 - 0.053 13.7 0.2 7 6.9 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 AAG07983.1 - 0.061 13.5 2.5 8.9 6.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 AAG07983.1 - 0.072 12.4 0.6 1.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 AAG07983.1 - 0.074 12.2 0.6 1.7 7.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_13 PF13166.6 AAG07983.1 - 0.11 11.1 6.9 4.4 5.8 0.0 3.7 3 1 0 4 4 4 0 AAA domain MukB PF04310.12 AAG07983.1 - 0.11 12.2 0.7 0.78 9.5 0.1 2.2 2 0 0 2 2 2 0 MukB N-terminal cobW PF02492.19 AAG07983.1 - 0.16 11.6 1.2 6.9 6.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AAG07983.1 - 0.19 12.1 7.0 3.3 8.1 2.5 3.1 2 1 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 AAG07983.1 - 0.29 9.9 2.6 2.5 6.8 1.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class TetR_N PF00440.23 AAG07984.1 - 0.00024 20.8 0.0 0.00085 19.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_24 PF13412.6 AAG07984.1 - 0.00038 20.0 0.2 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TetR_C_29 PF17938.1 AAG07984.1 - 0.0016 18.5 0.1 0.0045 17.1 0.1 1.7 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_Crp_2 PF13545.6 AAG07984.1 - 0.013 15.4 1.1 0.078 13.0 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain LacI PF00356.21 AAG07984.1 - 0.022 14.5 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MerR PF00376.23 AAG07984.1 - 0.036 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein HTH_10 PF04967.12 AAG07984.1 - 0.091 12.6 0.0 0.69 9.8 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_17 PF12728.7 AAG07984.1 - 0.099 12.8 0.1 0.54 10.5 0.1 2.4 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAG07984.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 HTH domain AbiEi_4 PF13338.6 AAG07984.1 - 0.12 12.5 2.7 0.63 10.2 0.0 3.0 3 1 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin GntR PF00392.21 AAG07984.1 - 0.15 11.8 2.8 13 5.5 0.4 2.7 2 1 1 3 3 3 0 Bacterial regulatory proteins, gntR family OEP PF02321.18 AAG07985.1 - 1.6e-53 181.3 30.8 2.7e-32 112.1 0.4 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein ACR_tran PF00873.19 AAG07986.1 - 0 1144.2 10.5 0 1144.0 10.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAG07986.1 - 3.2e-11 42.7 37.6 5.5e-09 35.4 15.3 2.3 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAG07986.1 - 0.0014 18.0 32.1 0.046 13.1 7.5 2.4 2 0 0 2 2 2 2 Protein export membrane protein Biotin_lipoyl_2 PF13533.6 AAG07987.1 - 3e-15 55.8 0.3 1.4e-10 40.8 0.1 3.4 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG07987.1 - 3.8e-12 45.9 0.3 1.4e-11 44.0 0.3 1.9 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG07987.1 - 3.4e-08 34.1 0.6 0.0051 17.5 0.0 2.7 2 1 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AAG07987.1 - 1.3e-06 28.2 13.5 3.5e-06 26.8 13.1 2.1 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAG07987.1 - 0.0048 16.7 0.0 0.53 10.2 0.0 2.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Trimer_CC PF08954.11 AAG07987.1 - 0.04 13.5 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 Trimerisation motif HTH_31 PF13560.6 AAG07988.1 - 3.2e-05 24.2 0.1 6.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAG07988.1 - 3.3e-05 23.6 0.2 0.00011 21.9 0.1 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain TetR_N PF00440.23 AAG07988.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_AsnC-type PF13404.6 AAG07988.1 - 0.00032 20.5 0.3 0.00066 19.5 0.3 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain LacI PF00356.21 AAG07988.1 - 0.0018 18.0 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_24 PF13412.6 AAG07988.1 - 0.0022 17.5 0.2 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 AAG07988.1 - 0.0046 16.9 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_10 PF04967.12 AAG07988.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 HTH DNA binding domain SpoIIID PF12116.8 AAG07988.1 - 0.0095 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_DeoR PF08220.12 AAG07988.1 - 0.018 14.8 0.2 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 AAG07988.1 - 0.037 13.9 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_Tnp_1_2 PF13022.6 AAG07988.1 - 0.045 13.9 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase TetR_C_29 PF17938.1 AAG07988.1 - 0.071 13.2 0.3 0.26 11.4 0.1 2.1 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_11 PF08279.12 AAG07988.1 - 0.093 12.7 0.1 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 HTH domain HTH_3 PF01381.22 AAG07988.1 - 0.098 12.7 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.6 AAG07988.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain EAL PF00563.20 AAG07989.1 - 2.6e-77 259.5 0.3 2.4e-76 256.4 0.0 2.3 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AAG07989.1 - 5.5e-52 175.8 0.1 1.5e-51 174.3 0.0 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAG07989.1 - 3.1e-36 123.8 0.0 9.3e-17 61.2 0.0 4.8 4 0 0 4 4 4 4 PAS domain PAS PF00989.25 AAG07989.1 - 7e-31 106.6 0.1 2.4e-09 37.2 0.0 5.4 4 1 0 4 4 4 4 PAS fold PAS_3 PF08447.12 AAG07989.1 - 1.4e-26 92.6 0.9 4.3e-14 52.6 0.9 4.7 4 1 0 4 4 4 3 PAS fold PAS_4 PF08448.10 AAG07989.1 - 2.6e-19 69.5 15.4 3.7e-06 27.1 0.0 6.9 6 1 0 6 6 5 5 PAS fold PAS_8 PF13188.7 AAG07989.1 - 2.4e-18 65.7 3.0 2e-07 30.9 0.0 6.3 6 0 0 6 6 6 3 PAS domain PAS_12 PF18095.1 AAG07989.1 - 0.002 17.8 0.0 2.8 7.6 0.0 3.5 4 0 0 4 4 4 2 UPF0242 C-terminal PAS-like domain PAS_7 PF12860.7 AAG07989.1 - 0.0085 16.2 0.0 2.9 8.1 0.0 4.6 5 1 0 5 5 5 1 PAS fold DUF4381 PF14316.6 AAG07989.1 - 0.012 15.9 8.2 4.2 7.6 0.6 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) GGDEF_2 PF17853.1 AAG07989.1 - 0.081 13.2 11.4 0.19 12.0 0.1 4.7 4 0 0 4 4 4 0 GGDEF-like domain SHMT PF00464.19 AAG07990.1 - 2.2e-182 606.1 0.2 2.6e-182 605.9 0.2 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AAG07990.1 - 1.8e-10 40.5 0.0 2.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAG07990.1 - 0.00013 21.4 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAG07990.1 - 0.00023 20.2 0.0 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAG07990.1 - 0.0017 17.0 0.0 0.0022 16.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAG07990.1 - 0.0024 17.3 0.1 0.0033 16.8 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 AAG07990.1 - 0.079 11.7 0.0 0.35 9.5 0.0 1.8 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain cobW PF02492.19 AAG07992.1 - 3.7e-52 176.5 0.1 4.7e-52 176.1 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAG07992.1 - 1.2e-20 73.2 0.0 2.1e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 AAG07992.1 - 0.0018 18.2 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 AAG07992.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAG07992.1 - 0.0079 16.4 0.6 0.058 13.5 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAG07992.1 - 0.0094 16.5 0.3 0.033 14.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAG07992.1 - 0.019 15.3 0.2 0.036 14.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 AAG07992.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 AAG07992.1 - 0.03 14.6 0.5 0.26 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 AAG07992.1 - 0.044 13.3 0.8 0.14 11.7 0.2 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_30 PF13604.6 AAG07992.1 - 0.078 12.7 0.4 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 AAG07992.1 - 0.094 12.2 0.0 13 5.3 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 AAG07992.1 - 0.1 11.6 0.2 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ank_3 PF13606.6 AAG07992.1 - 0.12 13.0 0.5 10 7.1 0.1 3.2 3 0 0 3 3 3 0 Ankyrin repeat ABC_tran PF00005.27 AAG07992.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 AAG07992.1 - 0.18 11.6 0.3 0.63 9.8 0.0 2.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain Sel_put PF04328.13 AAG07993.1 - 2.6e-30 104.2 1.0 2.8e-30 104.1 1.0 1.0 1 0 0 1 1 1 1 Selenoprotein, putative Lipase_GDSL_3 PF14606.6 AAG07993.1 - 0.066 13.3 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CstA PF02554.14 AAG07994.1 - 6e-169 561.8 24.5 1.5e-168 560.5 24.5 1.7 1 0 0 1 1 1 1 Carbon starvation protein CstA CstA_5TM PF13722.6 AAG07994.1 - 3.3e-36 124.2 7.9 3.3e-36 124.2 7.9 3.4 3 0 0 3 3 3 1 5TM C-terminal transporter carbon starvation CstA DUF3015 PF11220.8 AAG07995.1 - 3.4e-54 182.6 3.1 4e-54 182.4 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3015) PilZ PF07238.14 AAG07996.1 - 3.5e-12 46.5 0.1 4.3e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 PilZ domain ATPase PF06745.13 AAG07997.1 - 2.4e-17 63.1 0.1 1.7e-10 40.7 0.1 2.1 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 AAG07997.1 - 2.6e-14 53.2 0.2 1.3e-13 51.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain Rubredoxin_2 PF18073.1 AAG07997.1 - 8e-11 41.5 5.0 1.2e-10 40.9 5.0 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 AAG07997.1 - 2.2e-07 30.8 0.0 6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Rad51 PF08423.11 AAG07997.1 - 4.6e-06 26.1 1.1 6.5e-05 22.3 0.5 2.2 1 1 1 2 2 2 1 Rad51 Lon_C PF05362.13 AAG07997.1 - 6.2e-06 25.9 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain DnaB_C PF03796.15 AAG07997.1 - 9.6e-06 25.1 0.1 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 AAG07997.1 - 1.2e-05 25.8 0.3 0.0043 17.5 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 AAG07997.1 - 0.00019 21.9 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAG07997.1 - 0.0005 20.4 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 AAG07997.1 - 0.0011 18.5 0.6 0.0036 16.8 0.6 1.8 1 1 0 1 1 1 1 recA bacterial DNA recombination protein DUF2075 PF09848.9 AAG07997.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) GvpD PF07088.11 AAG07997.1 - 0.011 14.4 0.1 0.2 10.3 0.0 2.4 1 1 1 3 3 3 0 GvpD gas vesicle protein AAA_14 PF13173.6 AAG07997.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAG07997.1 - 0.012 15.4 0.0 0.062 13.0 0.0 2.2 2 1 1 3 3 2 0 AAA domain NTPase_1 PF03266.15 AAG07997.1 - 0.035 14.0 0.3 0.19 11.6 0.0 2.1 1 1 1 2 2 2 0 NTPase PAXNEB PF05625.11 AAG07997.1 - 0.036 13.2 0.7 0.06 12.5 0.7 1.3 1 0 0 1 1 1 0 PAXNEB protein MCM PF00493.23 AAG07997.1 - 0.054 12.6 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 AAG07997.1 - 0.091 12.7 0.3 0.34 10.8 0.3 1.9 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 AAG07997.1 - 0.13 12.8 0.1 0.26 11.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 AAG07997.1 - 0.17 11.7 0.2 0.5 10.1 0.1 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain CopD PF05425.13 AAG07998.1 - 4.2e-11 43.2 5.7 4.2e-11 43.2 5.7 1.7 1 1 1 2 2 2 1 Copper resistance protein D DUF2269 PF10027.9 AAG07998.1 - 0.00048 20.2 2.0 0.00048 20.2 2.0 1.7 2 1 0 2 2 2 1 Predicted integral membrane protein (DUF2269) DUF465 PF04325.13 AAG07999.1 - 1.3e-12 47.6 0.3 1.3e-12 47.6 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF465) DUF1192 PF06698.11 AAG07999.1 - 0.081 13.0 0.5 0.14 12.2 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Ank_5 PF13857.6 AAG08000.1 - 4.8e-22 77.7 4.0 1.2e-07 31.8 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 AAG08000.1 - 2.9e-17 62.8 0.1 1.7e-06 28.5 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 AAG08000.1 - 4.7e-16 59.1 0.0 6.3e-07 29.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 AAG08000.1 - 1.9e-11 43.9 0.2 0.011 16.1 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 AAG08000.1 - 1e-09 37.8 0.0 0.022 15.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Defensin_propep PF00879.18 AAG08000.1 - 0.054 13.8 0.1 0.16 12.2 0.1 1.9 1 0 0 1 1 1 0 Defensin propeptide Catalase PF00199.19 AAG08001.1 - 4.4e-164 546.1 0.0 5.3e-164 545.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AAG08001.1 - 1.4e-11 44.4 0.0 3.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF2250 PF10007.9 AAG08001.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) MscL PF01741.18 AAG08002.1 - 7.1e-45 152.2 1.1 8.1e-45 152.0 1.1 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DUF3487 PF11990.8 AAG08002.1 - 0.019 14.8 5.3 0.7 9.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) UPF0239 PF06783.11 AAG08002.1 - 0.096 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) NAD_binding_1 PF00175.21 AAG08003.1 - 2e-13 50.9 0.0 2.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAG08003.1 - 6.2e-06 26.5 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AAG08003.1 - 5.4e-05 23.4 0.0 0.00067 19.8 0.0 2.0 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 AAG08003.1 - 0.00066 19.7 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 FAD-binding domain DctP PF03480.13 AAG08004.1 - 1.2e-95 320.2 1.0 1.4e-95 320.0 1.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 JmjC PF02373.22 AAG08004.1 - 0.048 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase MTS PF05175.14 AAG08005.1 - 1.9e-53 180.5 0.0 1e-50 171.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 AAG08005.1 - 8.8e-10 38.6 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAG08005.1 - 6.4e-07 29.0 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 AAG08005.1 - 6.9e-06 26.7 0.1 1.9e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08005.1 - 3.5e-05 24.5 0.0 0.0001 23.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAG08005.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 AAG08005.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 AAG08005.1 - 0.04 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase UPF0020 PF01170.18 AAG08005.1 - 0.056 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GidB PF02527.15 AAG08005.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G XdhC_C PF13478.6 AAG08006.1 - 4.7e-35 120.8 0.1 8.2e-35 120.0 0.1 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AAG08006.1 - 4.9e-15 55.5 0.3 1.8e-14 53.6 0.3 2.1 1 0 0 1 1 1 1 XdhC and CoxI family Cytochrome_CBB3 PF13442.6 AAG08007.1 - 6.2e-22 77.7 0.7 1.3e-09 38.2 0.0 3.6 3 0 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG08007.1 - 5.3e-21 75.6 2.3 3.9e-08 34.3 0.0 3.9 3 1 0 3 3 3 3 Cytochrome c Cytochrome_C7 PF14522.6 AAG08007.1 - 0.00076 19.4 0.1 9.9 6.2 0.0 3.2 3 0 0 3 3 3 2 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AAG08007.1 - 0.0033 17.1 3.7 2.3 8.0 0.0 3.3 3 0 0 3 3 3 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_C1 PF02167.15 AAG08007.1 - 0.2 11.3 0.4 1.1 8.9 0.1 2.2 3 0 0 3 3 3 0 Cytochrome C1 family GSu_C4xC__C2xCH PF09698.10 AAG08007.1 - 0.29 11.9 4.2 12 6.8 0.0 3.5 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Cytochrom_C550 PF14495.6 AAG08007.1 - 1.9 8.2 7.5 6.6 6.4 0.0 3.4 4 1 0 5 5 5 0 Cytochrome c-550 domain Fer2_2 PF01799.20 AAG08008.1 - 9.6e-21 73.6 0.9 1.7e-20 72.8 0.2 1.7 2 0 0 2 2 2 1 [2Fe-2S] binding domain DHODB_Fe-S_bind PF10418.9 AAG08008.1 - 1.1e-05 25.2 2.2 2.1e-05 24.3 2.2 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Fer2 PF00111.27 AAG08008.1 - 0.00018 21.4 0.6 0.00018 21.4 0.6 1.8 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain CobW_C PF07683.14 AAG08008.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Ald_Xan_dh_C2 PF02738.18 AAG08009.1 - 2.5e-72 244.1 0.0 1.7e-53 181.9 0.0 2.3 2 0 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase TAT_signal PF10518.9 AAG08009.1 - 0.019 14.8 4.2 0.029 14.2 0.1 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence MFS_3 PF05977.13 AAG08010.1 - 3.6e-35 121.4 28.7 4.3e-35 121.1 28.7 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AAG08010.1 - 4.7e-27 94.8 37.4 4.7e-27 94.8 37.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LPAM_1 PF08139.12 AAG08011.1 - 0.017 15.6 1.2 0.034 14.6 1.2 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF2497 PF10691.9 AAG08011.1 - 0.034 14.6 3.2 7.4 7.1 0.2 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2497) POTRA_2 PF08479.11 AAG08012.1 - 1.4e-21 76.1 0.5 3.1e-21 75.0 0.2 1.7 2 0 0 2 2 2 1 POTRA domain, ShlB-type ShlB PF03865.13 AAG08012.1 - 2.5e-21 76.4 2.4 3.6e-21 75.9 2.4 1.2 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA PF07244.15 AAG08012.1 - 0.00066 20.2 0.2 0.0037 17.8 0.1 2.2 1 1 1 2 2 2 1 Surface antigen variable number repeat OMP_b-brl PF13505.6 AAG08012.1 - 0.0028 17.8 2.8 0.0061 16.7 2.2 1.9 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain Bac_surface_Ag PF01103.23 AAG08012.1 - 0.023 14.2 1.8 0.07 12.6 1.1 2.0 2 0 0 2 2 2 0 Surface antigen MBG_2 PF18676.1 AAG08013.1 - 1.4e-291 941.9 169.2 8.7e-21 74.3 3.1 16.4 16 0 0 16 16 16 15 MBG domain (YGX type) Haemagg_act PF05860.13 AAG08013.1 - 2.6e-22 79.0 4.7 2.6e-22 79.0 4.7 3.1 2 0 0 2 2 2 1 haemagglutination activity domain CBM_X2 PF03442.14 AAG08013.1 - 4.9e-07 29.8 64.5 4.8 7.4 0.3 13.8 13 0 0 13 13 13 11 Carbohydrate binding domain X2 TTR-52 PF01060.23 AAG08013.1 - 0.0015 19.2 0.0 9e+02 0.7 0.0 8.2 11 0 0 11 11 11 0 Transthyretin-like family Rimk_N PF18030.1 AAG08013.1 - 0.0032 17.8 0.0 2.1e+02 2.4 0.0 5.9 6 0 0 6 6 6 0 RimK PreATP-grasp domain B_solenoid_ydck PF18836.1 AAG08013.1 - 0.19 11.6 0.2 3.3 7.7 0.2 3.4 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK 2-Hacid_dh_C PF02826.19 AAG08014.1 - 9.3e-52 175.0 0.0 1.3e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAG08014.1 - 8.5e-26 90.2 0.0 1e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MTS PF05175.14 AAG08015.1 - 1.8e-54 183.8 0.0 7.2e-54 181.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain MTS_N PF08468.11 AAG08015.1 - 2e-40 138.4 0.0 4.4e-40 137.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain N-terminal Methyltransf_25 PF13649.6 AAG08015.1 - 1.4e-07 32.1 0.0 4.2e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08015.1 - 2.8e-05 24.0 0.0 4.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08015.1 - 0.00014 22.5 0.0 0.00074 20.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAG08015.1 - 0.00019 20.9 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 AAG08015.1 - 0.0044 16.9 0.0 0.26 11.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAG08015.1 - 0.0086 15.4 0.0 0.015 14.6 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 AAG08015.1 - 0.018 15.7 0.0 0.39 11.4 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 AAG08015.1 - 0.15 11.3 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AA_permease PF00324.21 AAG08016.1 - 4.4e-138 460.8 36.2 5e-138 460.7 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG08016.1 - 6.2e-42 143.9 41.8 6.2e-42 143.9 41.8 1.3 1 1 0 1 1 1 1 Amino acid permease YbgT_YccB PF08173.11 AAG08016.1 - 3.5 7.8 12.7 0.74 10.0 0.3 3.5 3 0 0 3 3 3 0 Membrane bound YbgT-like protein UPF0016 PF01169.19 AAG08017.1 - 1.1e-41 141.0 21.7 8.2e-22 77.3 6.5 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Acyl_transf_3 PF01757.22 AAG08017.1 - 0.00059 19.0 9.8 0.00082 18.5 9.8 1.2 1 0 0 1 1 1 1 Acyltransferase family TauE PF01925.19 AAG08017.1 - 0.001 18.8 17.1 0.0042 16.7 3.6 2.3 1 1 0 2 2 2 2 Sulfite exporter TauE/SafE SnoaL PF07366.12 AAG08018.1 - 1.6e-13 50.5 0.0 1.8e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 AAG08018.1 - 2.7e-08 34.4 0.0 3.2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Epimerase PF01370.21 AAG08019.1 - 6.5e-15 55.2 0.0 9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAG08019.1 - 1.2e-11 44.8 0.0 6.9e-11 42.4 0.0 2.0 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 AAG08019.1 - 1.9e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 AAG08019.1 - 0.00027 20.0 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAG08019.1 - 0.0082 15.3 0.0 0.042 13.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Peptidase_M48 PF01435.18 AAG08020.1 - 2.9e-40 138.1 0.0 3.7e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 MLTD_N PF06474.12 AAG08020.1 - 0.023 14.9 0.5 0.023 14.9 0.5 2.1 2 0 0 2 2 2 0 MltD lipid attachment motif DUF2201_N PF13203.6 AAG08020.1 - 0.052 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain MCPsignal PF00015.21 AAG08021.1 - 9.5e-46 155.7 50.1 6.8e-45 153.0 30.4 3.1 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAG08021.1 - 6.9e-16 58.8 0.0 6.9e-16 58.8 0.0 3.4 2 1 0 2 2 1 1 Cache domain HAMP PF00672.25 AAG08021.1 - 4.8e-10 39.7 7.6 1.1e-09 38.5 0.1 4.8 4 1 1 5 5 5 1 HAMP domain XPC-binding PF09280.11 AAG08021.1 - 0.0069 16.1 4.6 3.9 7.3 2.6 3.3 2 0 0 2 2 2 2 XPC-binding domain CheZ PF04344.13 AAG08021.1 - 0.014 15.3 15.2 0.11 12.4 2.8 2.8 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF948 PF06103.11 AAG08021.1 - 0.02 15.2 1.9 0.02 15.2 1.9 6.2 3 3 2 5 5 5 0 Bacterial protein of unknown function (DUF948) YwiC PF14256.6 AAG08021.1 - 0.039 14.3 0.7 0.12 12.7 0.1 2.0 2 0 0 2 2 2 0 YwiC-like protein NOG1 PF06858.14 AAG08021.1 - 0.055 13.3 0.2 0.15 11.8 0.2 1.8 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) FAM217 PF15344.6 AAG08021.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 FAM217 family Fib_alpha PF08702.10 AAG08021.1 - 0.28 11.3 13.9 1.2 9.3 4.5 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 AAG08021.1 - 0.42 11.0 11.8 0.25 11.8 5.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) LMBR1 PF04791.16 AAG08021.1 - 0.43 9.4 5.1 1.8 7.4 5.0 1.9 1 1 0 1 1 1 0 LMBR1-like membrane protein Syntaxin-6_N PF09177.11 AAG08021.1 - 0.67 10.5 11.2 0.35 11.5 4.1 3.4 3 1 0 3 3 2 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 AAG08021.1 - 0.71 10.3 20.4 0.17 12.3 0.4 4.7 3 1 2 5 5 3 0 Syntaxin-like protein DUF4618 PF15397.6 AAG08021.1 - 0.9 8.9 13.4 0.22 10.9 5.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) FH2 PF02181.23 AAG08021.1 - 1.1 8.3 7.2 1.6 7.8 1.2 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain IFT57 PF10498.9 AAG08021.1 - 1.2 8.0 11.6 0.21 10.5 4.6 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 AAG08021.1 - 1.5 9.2 20.0 6.9 7.0 0.8 5.0 2 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.19 AAG08021.1 - 5.4 6.8 24.7 0.47 10.2 12.8 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Leu_zip PF15294.6 AAG08021.1 - 6 6.3 12.9 3.7 7.0 5.4 2.2 2 0 0 2 2 2 0 Leucine zipper TMPIT PF07851.13 AAG08021.1 - 6.6 5.9 9.0 3.4 6.8 2.8 2.3 2 0 0 2 2 2 0 TMPIT-like protein TMF_TATA_bd PF12325.8 AAG08021.1 - 7.2 6.9 16.2 13 6.1 5.0 3.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 AAG08021.1 - 7.6 6.6 27.3 13 5.9 3.1 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SRAP PF02586.14 AAG08022.1 - 1.2e-33 116.5 0.0 1.6e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) MgtC PF02308.16 AAG08023.1 - 1.9e-35 121.8 12.4 6.4e-35 120.2 13.2 1.4 2 0 0 2 2 2 1 MgtC family ACT_4 PF13291.6 AAG08023.1 - 0.047 14.3 0.1 0.42 11.2 0.0 2.4 3 1 0 3 3 3 0 ACT domain Acyltransferase PF01553.21 AAG08024.1 - 1.3e-08 34.6 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_14 PF13428.6 AAG08024.1 - 0.39 11.7 2.0 0.79 10.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat LapA_dom PF06305.11 AAG08025.1 - 0.01 15.7 2.7 0.52 10.2 0.8 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF5134 PF17197.4 AAG08025.1 - 0.15 11.9 5.4 0.086 12.7 3.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Lipoprotein_16 PF03923.13 AAG08027.1 - 7.2e-12 45.2 0.0 8.3e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized lipoprotein Mqo PF06039.15 AAG08028.1 - 1.9e-232 772.1 0.0 2.2e-232 771.9 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 AAG08028.1 - 1.4e-12 47.9 0.0 1.7e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AAG08028.1 - 9.6e-05 21.8 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 AAG08028.1 - 0.0003 20.1 0.3 0.00062 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 AAG08028.1 - 0.00072 18.8 0.0 0.39 9.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 AAG08028.1 - 0.08 12.0 0.0 2.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Cupin_2 PF07883.11 AAG08031.1 - 0.0059 16.3 0.4 0.019 14.6 0.0 2.1 2 1 0 2 2 2 1 Cupin domain Pribosyltran PF00156.27 AAG08032.1 - 2.2e-24 85.8 0.0 2.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAG08033.1 - 6.5e-63 211.9 0.0 7.5e-63 211.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 AAG08033.1 - 7.9e-16 58.0 1.1 1.1e-15 57.5 1.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Xan_ur_permease PF00860.20 AAG08034.1 - 1.2e-92 310.6 44.0 1.2e-92 310.6 44.0 1.3 2 0 0 2 2 2 1 Permease family SCPU PF05229.15 AAG08035.1 - 1e-32 113.4 10.1 1.2e-32 113.2 10.1 1.0 1 0 0 1 1 1 1 Spore Coat Protein U domain Fimbrial PF00419.20 AAG08035.1 - 0.0039 17.5 6.8 0.005 17.1 6.8 1.2 1 0 0 1 1 1 1 Fimbrial protein SCPU PF05229.15 AAG08036.1 - 4.4e-35 121.1 7.9 5.1e-35 120.9 7.9 1.0 1 0 0 1 1 1 1 Spore Coat Protein U domain CBM_6 PF03422.15 AAG08036.1 - 0.061 13.6 0.5 0.061 13.6 0.5 1.8 1 1 1 2 2 2 0 Carbohydrate binding module (family 6) TadE PF07811.12 AAG08036.1 - 0.095 13.0 0.2 0.27 11.5 0.2 1.7 1 0 0 1 1 1 0 TadE-like protein SCPU PF05229.15 AAG08037.1 - 3.9e-36 124.5 7.0 4.4e-36 124.3 7.0 1.0 1 0 0 1 1 1 1 Spore Coat Protein U domain PapD_N PF00345.20 AAG08038.1 - 5.6e-18 65.0 0.0 1.3e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Usher PF00577.20 AAG08039.1 - 1.3e-23 83.7 1.4 2.1e-22 79.7 1.4 2.0 1 1 0 1 1 1 1 Outer membrane usher protein PapC_C PF13953.6 AAG08039.1 - 4.7e-15 55.2 0.0 1.6e-14 53.5 0.0 2.0 1 0 0 1 1 1 1 PapC C-terminal domain PapC_N PF13954.6 AAG08039.1 - 0.02 14.9 0.0 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 PapC N-terminal domain SCPU PF05229.15 AAG08040.1 - 8.7e-57 191.4 20.7 1.4e-31 109.7 4.5 2.0 2 0 0 2 2 2 2 Spore Coat Protein U domain BA14K PF07886.11 AAG08040.1 - 0.11 12.4 0.2 0.3 11.0 0.2 1.8 1 0 0 1 1 1 0 BA14K-like protein MFS_1 PF07690.16 AAG08041.1 - 2.3e-45 155.1 39.4 2.3e-45 155.1 39.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 AAG08041.1 - 1.3e-05 23.8 3.7 1.3e-05 23.8 3.7 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.24 AAG08041.1 - 2e-05 23.7 7.9 2e-05 23.7 7.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 AAG08041.1 - 9.8e-05 20.8 9.8 0.0034 15.7 1.1 2.7 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Ferrochelatase PF00762.19 AAG08042.1 - 6.9e-99 330.9 0.0 8.5e-99 330.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 AAG08042.1 - 0.0019 18.5 0.0 3 8.2 0.0 2.5 2 0 0 2 2 2 2 CbiX Epimerase PF01370.21 AAG08043.1 - 2.4e-25 89.4 0.0 3.8e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1731 PF08338.11 AAG08043.1 - 1e-20 73.3 0.3 2.1e-20 72.2 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) NAD_binding_2 PF03446.15 AAG08043.1 - 0.00033 20.9 0.0 0.00066 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_trans_4_4 PF13579.6 AAG08043.1 - 0.0021 18.5 5.1 0.0024 18.4 1.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain GDP_Man_Dehyd PF16363.5 AAG08043.1 - 0.015 14.7 0.0 11 5.2 0.0 2.9 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAG08043.1 - 0.023 13.8 0.0 0.054 12.6 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 AAG08043.1 - 0.029 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_transf_4 PF13439.6 AAG08043.1 - 0.067 13.2 0.4 0.27 11.2 0.2 2.1 2 1 0 2 2 2 0 Glycosyltransferase Family 4 F420_oxidored PF03807.17 AAG08043.1 - 0.071 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Amino_oxidase PF01593.24 AAG08044.1 - 1.7e-20 73.8 3.7 7.2e-11 42.0 0.2 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAG08044.1 - 1.6e-15 57.0 0.9 3.4e-15 56.0 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG08044.1 - 1.1e-06 28.1 0.0 1.2e-05 24.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG08044.1 - 1.2e-06 27.9 0.2 2.3e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAG08044.1 - 3.6e-05 23.5 3.2 0.00013 21.7 3.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAG08044.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG08044.1 - 0.0011 17.7 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 AAG08044.1 - 0.0017 18.4 0.1 0.0038 17.2 0.1 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 AAG08044.1 - 0.0035 16.7 0.2 0.0052 16.1 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AAG08044.1 - 0.012 14.8 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAG08044.1 - 0.012 14.9 0.9 0.016 14.4 0.5 1.4 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 AAG08044.1 - 0.025 14.2 0.8 0.79 9.3 0.5 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 AAG08044.1 - 0.098 13.2 0.1 0.18 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG08044.1 - 0.1 11.8 0.2 1.2 8.4 0.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1722 PF08349.11 AAG08045.1 - 2.5e-41 140.6 0.1 3.4e-41 140.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) DUF523 PF04463.12 AAG08045.1 - 8.2e-34 116.6 0.0 1.1e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF523) TAL_effector PF03377.13 AAG08045.1 - 0.0048 17.2 0.1 0.026 14.8 0.1 2.3 1 1 1 2 2 2 1 TAL effector repeat MerR_1 PF13411.6 AAG08046.1 - 3.7e-18 65.4 0.4 9.2e-18 64.1 0.4 1.6 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAG08046.1 - 2.4e-12 46.4 1.1 7.3e-12 44.9 0.7 2.1 2 0 0 2 2 2 1 MerR family regulatory protein B12-binding_2 PF02607.17 AAG08046.1 - 0.0046 17.4 0.1 0.0097 16.3 0.1 1.4 1 0 0 1 1 1 1 B12 binding domain HTH_23 PF13384.6 AAG08046.1 - 0.0048 16.7 0.8 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 AAG08046.1 - 0.0053 17.1 0.2 0.028 14.7 0.1 2.2 1 1 1 2 2 2 1 Transposase HTH_28 PF13518.6 AAG08046.1 - 0.028 14.5 0.4 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4349 PF14257.6 AAG08046.1 - 0.029 13.8 0.1 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HTH_17 PF12728.7 AAG08046.1 - 0.031 14.5 0.1 0.066 13.4 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain BRCC36_C PF18110.1 AAG08046.1 - 0.077 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain FAD_binding_7 PF03441.14 AAG08047.1 - 2.1e-82 275.5 0.3 3.1e-82 275.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AAG08047.1 - 3.8e-44 150.6 0.1 6.2e-44 149.9 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase PagL PF09411.10 AAG08048.1 - 1.7e-41 141.5 2.8 2e-41 141.3 2.8 1.1 1 0 0 1 1 1 1 Lipid A 3-O-deacylase (PagL) OprF PF05736.11 AAG08048.1 - 0.0057 16.4 0.1 0.0081 15.9 0.1 1.2 1 0 0 1 1 1 1 OprF membrane domain TDP43_N PF18694.1 AAG08048.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain Asp_Glu_race PF01177.22 AAG08049.1 - 3.7e-37 128.3 0.0 4.6e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase ThiF PF00899.21 AAG08050.1 - 5.4e-60 202.8 0.1 6.7e-60 202.5 0.1 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AAG08050.1 - 3.5e-05 24.1 0.5 7.6e-05 23.0 0.5 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TPR_5 PF12688.7 AAG08050.1 - 0.063 13.5 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat MTS PF05175.14 AAG08051.1 - 1e-15 57.7 0.0 9.2e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmC_N PF17827.1 AAG08051.1 - 2.1e-15 57.1 3.0 2.2e-15 57.0 0.0 2.5 3 1 0 3 3 3 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 AAG08051.1 - 1.3e-14 54.2 0.0 1.9e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08051.1 - 1.2e-06 29.1 0.0 2.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG08051.1 - 6.2e-06 26.2 0.0 1.9e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08051.1 - 6.1e-05 23.6 0.0 0.00021 21.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 AAG08051.1 - 0.00024 20.6 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 AAG08051.1 - 0.00036 20.0 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 AAG08051.1 - 0.00045 19.9 0.0 0.00066 19.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 AAG08051.1 - 0.0013 19.5 0.0 0.0069 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 AAG08051.1 - 0.0021 17.8 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 AAG08051.1 - 0.0022 17.9 0.0 0.0046 16.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 AAG08051.1 - 0.0028 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.19 AAG08051.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 AAG08051.1 - 0.022 14.0 0.1 0.23 10.7 0.0 2.3 3 0 0 3 3 3 0 O-methyltransferase domain TehB PF03848.14 AAG08051.1 - 0.043 13.2 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.18 AAG08051.1 - 0.049 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 AAG08051.1 - 0.23 11.5 0.0 0.32 11.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PCRF PF03462.18 AAG08052.1 - 9.3e-74 247.5 0.4 2.3e-73 246.2 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AAG08052.1 - 2.2e-42 143.7 1.0 4.1e-42 142.8 1.0 1.4 1 0 0 1 1 1 1 RF-1 domain ABC_tran_CTD PF16326.5 AAG08052.1 - 0.19 12.0 6.4 0.19 12.0 0.0 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain HR1 PF02185.16 AAG08052.1 - 0.27 11.4 0.1 0.27 11.4 0.1 2.6 2 0 0 2 2 2 0 Hr1 repeat GlutR_N PF05201.15 AAG08053.1 - 3e-52 176.3 0.1 5.9e-52 175.3 0.1 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AAG08053.1 - 2.2e-50 170.3 0.1 4.5e-50 169.3 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AAG08053.1 - 6.7e-24 84.2 1.1 1.8e-23 82.8 1.1 1.8 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 AAG08053.1 - 5.6e-05 23.6 0.1 0.00037 21.0 0.1 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAG08053.1 - 0.0083 16.4 0.2 0.1 12.9 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 AAG08053.1 - 0.033 14.6 0.2 0.098 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding VirB8 PF04335.13 AAG08053.1 - 0.048 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 VirB8 protein TPR_16 PF13432.6 AAG08054.1 - 8.3e-31 106.4 47.0 7.5e-08 32.9 2.1 8.8 7 1 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 AAG08054.1 - 1.9e-27 93.6 51.9 0.00027 21.5 0.6 12.4 5 4 8 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 AAG08054.1 - 1.2e-26 93.0 45.8 1.4e-10 41.5 0.9 7.9 3 2 5 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 AAG08054.1 - 3e-20 70.7 39.8 5.1e-05 23.1 0.1 12.4 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 AAG08054.1 - 2.2e-17 62.4 31.5 0.0032 18.0 0.1 11.5 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 AAG08054.1 - 3.2e-15 55.3 16.4 0.023 15.1 0.0 9.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAG08054.1 - 1.2e-13 51.1 39.3 5.3e-06 26.6 1.7 8.7 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 AAG08054.1 - 2e-10 40.0 14.5 1.1 9.6 0.0 10.6 12 0 0 12 12 11 2 Tetratricopeptide repeat Coatomer_E PF04733.14 AAG08054.1 - 2.9e-08 33.5 1.3 0.17 11.3 0.2 4.5 3 1 2 5 5 5 3 Coatomer epsilon subunit TPR_1 PF00515.28 AAG08054.1 - 4e-08 32.7 16.7 0.0021 17.8 0.0 8.3 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 AAG08054.1 - 1.2e-07 32.0 29.4 0.15 12.4 0.3 8.0 3 1 3 7 7 7 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AAG08054.1 - 4.3e-07 29.6 14.0 0.001 18.7 0.1 5.4 2 1 2 5 5 5 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 AAG08054.1 - 8.3e-07 28.9 25.5 0.22 11.2 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 AAG08054.1 - 1.2e-06 28.6 11.8 0.32 11.2 0.0 6.1 3 3 5 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AAG08054.1 - 2.3e-06 27.3 37.9 0.0061 16.4 0.6 9.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_4 PF07721.14 AAG08054.1 - 6.4e-06 26.3 49.6 0.0079 16.7 3.2 9.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 AAG08054.1 - 1.1e-05 25.0 5.9 0.5 10.1 0.0 6.2 6 0 0 6 6 6 1 TPR repeat TPR_15 PF13429.6 AAG08054.1 - 0.00056 19.2 32.2 0.022 14.0 7.0 5.3 1 1 3 4 4 4 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 AAG08054.1 - 0.0012 18.8 9.0 0.73 9.7 0.1 4.4 4 2 1 5 5 5 1 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 AAG08054.1 - 0.0022 18.1 39.8 0.12 12.5 0.9 7.2 4 4 4 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AAG08054.1 - 0.005 16.9 2.9 2.1 8.5 0.1 4.7 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat SLT_L PF14718.6 AAG08054.1 - 0.011 15.8 5.0 1.2 9.4 0.2 4.0 3 1 1 4 4 3 0 Soluble lytic murein transglycosylase L domain DUF4810 PF16068.5 AAG08054.1 - 0.016 15.7 0.7 28 5.3 0.0 5.3 6 2 1 7 7 5 0 Domain of unknown function (DUF4810) ChAPs PF09295.10 AAG08054.1 - 0.018 14.1 0.2 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 AAG08054.1 - 0.025 14.6 18.2 13 6.1 0.6 7.5 8 1 0 8 8 7 0 Tetratricopeptide repeat HemY_N PF07219.13 AAG08054.1 - 0.048 13.9 3.4 8.2 6.7 0.1 3.8 2 2 1 3 3 3 0 HemY protein N-terminus Sigma70_r3 PF04539.16 AAG08054.1 - 0.054 13.6 0.2 1.8 8.7 0.1 3.3 3 0 0 3 3 3 0 Sigma-70 region 3 NYD-SP28_assoc PF14775.6 AAG08054.1 - 0.16 12.1 0.8 0.63 10.2 0.8 2.1 1 0 0 1 1 1 0 Sperm tail C-terminal domain LolB PF03550.14 AAG08055.1 - 4.1e-49 166.5 0.9 5.2e-49 166.2 0.9 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein LolB DUF4148 PF13663.6 AAG08055.1 - 0.0092 16.1 0.3 0.036 14.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4148) LPAM_1 PF08139.12 AAG08055.1 - 0.055 14.0 4.8 0.1 13.1 4.8 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Yop-YscD_ppl PF16693.5 AAG08055.1 - 0.2 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain GHMP_kinases_N PF00288.26 AAG08056.1 - 9.1e-11 41.8 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAG08056.1 - 1.3e-05 25.5 0.0 2.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Pribosyltran_N PF13793.6 AAG08057.1 - 7.1e-50 167.8 0.2 2.2e-48 163.0 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AAG08057.1 - 3.9e-33 115.0 2.6 1.2e-32 113.4 0.7 2.3 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AAG08057.1 - 1.4e-20 73.4 2.9 6.6e-20 71.2 1.4 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAG08057.1 - 0.018 14.5 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase E3_binding PF02817.17 AAG08057.1 - 0.08 13.3 0.5 9.2 6.7 0.2 2.7 2 0 0 2 2 2 0 e3 binding domain Ribosomal_TL5_C PF14693.6 AAG08058.1 - 3e-29 101.2 1.3 4.9e-29 100.5 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 AAG08058.1 - 3.3e-27 94.8 0.0 6.8e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L25p family Arfaptin PF06456.13 AAG08058.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain Pept_tRNA_hydro PF01195.19 AAG08059.1 - 5.9e-54 182.6 0.0 6.8e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase YchF-GTPase_C PF06071.13 AAG08060.1 - 1.2e-41 140.8 0.5 2.3e-41 139.9 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AAG08060.1 - 3e-22 78.9 0.0 7.1e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAG08060.1 - 8.3e-08 31.9 0.1 3.3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 AAG08060.1 - 0.0021 18.1 0.2 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 TGS domain RNA_helicase PF00910.22 AAG08060.1 - 0.13 12.6 0.0 31 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase HTH_3 PF01381.22 AAG08061.1 - 5e-06 26.5 0.0 6.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix YdaS_antitoxin PF15943.5 AAG08061.1 - 0.00049 19.9 0.0 0.00083 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_24 PF13412.6 AAG08061.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 AAG08061.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AAG08061.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 AAG08061.1 - 0.071 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAG08061.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.6 AAG08061.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_26 PF13443.6 AAG08061.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain TonB_dep_Rec PF00593.24 AAG08062.1 - 1.1e-30 108.0 33.3 1.1e-30 108.0 33.3 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG08062.1 - 1e-19 71.1 1.8 2.4e-19 69.9 1.8 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF560 PF04575.13 AAG08062.1 - 0.065 12.7 1.8 0.15 11.5 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF560) Pro_CA PF00484.19 AAG08063.1 - 7.2e-50 169.3 0.2 8.7e-50 169.0 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase P-mevalo_kinase PF04275.14 AAG08063.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphomevalonate kinase Peptidase_C69 PF03577.15 AAG08064.1 - 1.1e-08 34.4 0.0 1.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 AAG08064.1 - 0.00019 21.2 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Acetyltransf_1 PF00583.25 AAG08065.1 - 2.6e-16 59.9 0.2 3.2e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG08065.1 - 1.1e-14 54.4 0.1 1.4e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG08065.1 - 5.3e-12 46.0 0.2 6.8e-12 45.7 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG08065.1 - 1e-10 41.4 0.1 1.6e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAG08065.1 - 2.8e-07 30.7 0.0 1.1e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAG08065.1 - 2.1e-05 25.2 0.2 8e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAG08065.1 - 0.00018 21.2 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG08065.1 - 0.079 13.1 0.0 0.091 12.9 0.0 1.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAG08065.1 - 0.081 12.6 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 AAG08065.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TraW_N PF12477.8 AAG08068.1 - 0.45 10.5 2.5 1.7 8.7 2.5 2.0 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal DUF4194 PF13835.6 AAG08072.1 - 5e-05 23.1 0.8 0.00048 19.9 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4194) MukE PF04288.13 AAG08072.1 - 0.025 13.5 0.3 0.075 12.0 0.1 1.8 2 0 0 2 2 2 0 MukE-like family DUF2812 PF11193.8 AAG08072.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) DUF1993 PF09351.10 AAG08073.1 - 0.075 13.2 0.2 0.075 13.2 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) efb-c PF12199.8 AAG08073.1 - 0.075 13.1 0.5 0.24 11.5 0.1 2.0 1 1 1 2 2 2 0 Extracellular fibrinogen binding protein C terminal DUF4726 PF15855.5 AAG08073.1 - 0.63 10.3 3.2 1.8 8.9 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) DUF1664 PF07889.12 AAG08073.1 - 0.74 9.9 16.6 0.71 9.9 0.1 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4279 PF14106.6 AAG08073.1 - 0.82 9.9 3.0 19 5.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) Matrilin_ccoil PF10393.9 AAG08073.1 - 2.5 8.0 5.0 25 4.8 0.2 2.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Sugarporin_N PF11471.8 AAG08073.1 - 3.7 7.6 12.2 0.072 13.1 1.0 3.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DASH_Dad2 PF08654.10 AAG08073.1 - 4.5 7.8 16.6 17 5.9 0.9 4.3 3 1 1 4 4 4 0 DASH complex subunit Dad2 SBP_bac_6 PF13343.6 AAG08074.1 - 9.7e-28 97.2 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAG08074.1 - 8.3e-26 91.4 0.1 1e-25 91.1 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG08074.1 - 7.4e-23 81.5 0.1 1e-22 81.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG08074.1 - 2.2e-21 77.1 1.1 4.3e-21 76.2 1.1 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_3 PF00497.20 AAG08074.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAG08074.1 - 0.026 14.5 0.1 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 NMT1/THI5 like BPD_transp_1 PF00528.22 AAG08075.1 - 1.4e-24 86.8 33.1 9.3e-15 54.8 10.1 3.9 2 2 2 4 4 4 2 Binding-protein-dependent transport system inner membrane component HTH_8 PF02954.19 AAG08075.1 - 0.081 12.7 0.2 3 7.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Saf_2TM PF18303.1 AAG08075.1 - 4.6 6.8 5.8 1.2 8.8 0.2 2.7 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain MlaD PF02470.20 AAG08076.1 - 2.3e-72 239.3 4.3 2e-11 44.0 0.4 6.2 6 0 0 6 6 6 6 MlaD protein Ferric_reduct PF01794.19 AAG08077.1 - 5.2e-17 62.1 7.8 1.2e-16 61.0 7.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Oxidored_molyb PF00174.19 AAG08078.1 - 8.5e-32 110.1 0.0 6.6e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain CDP-OH_P_transf PF01066.21 AAG08079.1 - 5.8e-13 49.4 1.4 5.8e-13 49.4 1.4 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PsbT PF01405.17 AAG08079.1 - 0.019 14.8 3.5 0.063 13.1 3.5 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Polysacc_synt_C PF14667.6 AAG08079.1 - 4.4 7.4 17.2 0.27 11.3 7.2 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF2976 PF11190.8 AAG08079.1 - 9.1 6.2 10.9 0.44 10.4 3.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) IlvN PF07991.12 AAG08080.1 - 2.8e-75 251.4 2.4 3.6e-75 251.1 2.4 1.1 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AAG08080.1 - 2.9e-63 212.5 0.1 3.9e-63 212.0 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 AAG08080.1 - 1.7e-07 30.8 0.1 2.6e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAG08080.1 - 3.1e-06 27.4 0.1 8.7e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAG08080.1 - 1.3e-05 25.7 0.2 2.7e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AAG08080.1 - 0.00011 22.3 0.7 0.00018 21.6 0.2 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 AAG08080.1 - 0.00022 20.9 0.3 0.00049 19.8 0.3 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 AAG08080.1 - 0.0083 16.6 0.2 0.023 15.1 0.2 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding CoA_binding PF02629.19 AAG08080.1 - 0.011 16.4 0.3 0.031 14.9 0.3 1.8 1 0 0 1 1 1 0 CoA binding domain PDH PF02153.17 AAG08080.1 - 0.018 14.1 0.2 0.043 12.8 0.1 1.6 2 0 0 2 2 2 0 Prephenate dehydrogenase Shikimate_DH PF01488.20 AAG08080.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 AAG08080.1 - 0.033 14.2 0.3 2.7 8.0 0.1 2.4 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 AAG08080.1 - 0.083 13.7 0.1 0.19 12.6 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ALS_ss_C PF10369.9 AAG08081.1 - 2.5e-27 94.9 2.2 1.7e-26 92.2 0.7 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 AAG08081.1 - 2.1e-15 56.3 0.0 4.1e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AAG08081.1 - 5.6e-15 54.8 0.0 1.1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AAG08081.1 - 0.0055 17.3 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 ACT domain TPP_enzyme_N PF02776.18 AAG08082.1 - 4.3e-60 202.2 0.1 3.5e-59 199.2 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAG08082.1 - 4.5e-51 172.7 0.3 7.5e-49 165.4 0.0 3.0 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG08082.1 - 1.1e-43 148.3 0.1 3.6e-43 146.6 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AAG08082.1 - 0.00063 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PPS_PS PF02006.16 AAG08082.1 - 0.12 11.9 0.3 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Phosphopantothenate/pantothenate synthetase DUF4191 PF13829.6 AAG08082.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4124 PF13511.6 AAG08083.1 - 1.1e-15 57.7 9.3 3e-15 56.3 9.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4124) DUF737 PF05300.11 AAG08083.1 - 0.0078 16.6 5.6 0.0097 16.3 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF737) LPAM_1 PF08139.12 AAG08083.1 - 0.04 14.4 0.7 0.058 13.9 0.7 1.2 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Caudo_TAP PF02413.17 AAG08083.1 - 1.7 8.8 8.7 6.7 6.9 0.5 2.2 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK DUF446 PF04287.12 AAG08084.1 - 1.4e-32 111.7 0.1 1.5e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase C TPR_15 PF13429.6 AAG08085.1 - 2.1e-05 23.9 4.0 2.9e-05 23.4 4.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAG08085.1 - 2.3e-05 24.9 7.4 2.3e-05 24.9 7.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAG08085.1 - 9.5e-05 22.8 6.1 9.5e-05 22.8 6.1 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAG08085.1 - 0.00025 21.0 0.4 0.93 9.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAG08085.1 - 0.0016 18.4 6.0 0.24 11.6 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAG08085.1 - 0.0037 18.0 11.6 0.032 15.1 4.2 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 AAG08085.1 - 0.0045 17.5 4.3 0.0045 17.5 4.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAG08085.1 - 0.0054 17.0 0.8 0.054 13.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AAG08085.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_MalT PF17874.1 AAG08085.1 - 0.031 13.6 7.5 0.05 13.0 7.5 1.3 1 0 0 1 1 1 0 MalT-like TPR region TPR_21 PF09976.9 AAG08085.1 - 0.043 13.5 6.5 0.072 12.8 6.5 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 AAG08085.1 - 0.17 11.8 1.4 0.32 10.9 1.4 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal SOG2 PF10428.9 AAG08085.1 - 0.86 8.7 3.6 1 8.5 3.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TPR_7 PF13176.6 AAG08085.1 - 0.87 9.8 3.3 6.3 7.1 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAG08085.1 - 1.3 9.3 7.3 2.1 8.7 3.8 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAG08085.1 - 3.8 8.4 11.6 0.57 10.9 1.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Transgly PF00912.22 AAG08086.1 - 4e-57 192.5 0.0 6.1e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase UB2H PF14814.6 AAG08086.1 - 2.1e-24 85.4 0.0 4.9e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain Transpeptidase PF00905.22 AAG08086.1 - 1.7e-18 66.9 0.0 8.8e-18 64.5 0.0 1.9 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain UvrB_inter PF17757.1 AAG08086.1 - 8.8e-05 22.6 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain AAA_33 PF13671.6 AAG08087.1 - 6.2e-38 130.2 0.1 1.1e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain APH PF01636.23 AAG08087.1 - 1.1e-05 25.5 3.7 1.1e-05 25.5 3.7 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family KTI12 PF08433.10 AAG08087.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Pentapeptide PF00805.22 AAG08088.1 - 2.3e-15 55.9 0.9 6e-10 38.6 0.0 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 AAG08088.1 - 5.5e-05 23.2 0.1 9.3e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 AAG08088.1 - 0.00012 22.2 0.0 0.00016 21.8 0.0 1.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) TfoX_C PF04994.13 AAG08089.1 - 5.2e-28 96.9 0.1 5.8e-28 96.8 0.1 1.0 1 0 0 1 1 1 1 TfoX C-terminal domain Cdd1 PF11731.8 AAG08089.1 - 0.048 13.9 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity locus cNMP_binding PF00027.29 AAG08090.1 - 2.5e-24 85.2 0.1 1.3e-21 76.5 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 AAG08090.1 - 0.011 15.4 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Cupin domain Cofac_haem_bdg PF04187.13 AAG08091.1 - 3.5e-44 151.3 0.4 5.1e-44 150.8 0.4 1.2 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN ABC_tran PF00005.27 AAG08092.1 - 2.1e-24 86.6 0.0 2.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG08092.1 - 4e-08 33.4 0.4 0.0072 16.2 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG08092.1 - 3e-06 26.8 0.0 0.023 14.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG08092.1 - 0.00022 21.7 1.1 0.00053 20.4 1.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG08092.1 - 0.001 18.7 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG08092.1 - 0.0023 18.5 0.0 0.0029 18.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAG08092.1 - 0.0041 16.7 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAG08092.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AAG08092.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 AAG08092.1 - 0.079 12.7 0.5 0.56 9.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG08092.1 - 0.13 12.5 0.0 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 AAG08092.1 - 0.14 12.3 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain TrkA_C PF02080.21 AAG08092.1 - 0.14 12.0 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 TrkA-C domain FecCD PF01032.18 AAG08093.1 - 1.8e-89 299.9 30.1 2e-89 299.7 30.1 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AAG08093.1 - 0.025 14.1 8.8 0.047 13.2 8.8 1.5 1 0 0 1 1 1 0 ABC 3 transport family Peripla_BP_2 PF01497.18 AAG08094.1 - 8.7e-31 107.3 0.0 1e-30 107.1 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein HemS PF05171.12 AAG08095.1 - 2.2e-87 289.5 0.0 1.2e-42 144.9 0.0 2.2 2 0 0 2 2 2 2 Haemin-degrading HemS.ChuX domain ChuX_HutX PF06228.13 AAG08095.1 - 9.3e-65 216.4 0.0 6.1e-37 126.4 0.0 2.3 2 0 0 2 2 2 2 Haem utilisation ChuX/HutX TonB_dep_Rec PF00593.24 AAG08096.1 - 4.1e-65 221.5 35.1 4.1e-65 221.5 35.1 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG08096.1 - 6e-28 97.6 4.1 6.5e-28 97.5 1.9 2.2 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAG08096.1 - 1.6e-13 50.4 5.9 2.6e-13 49.8 5.9 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family Rieske PF00355.26 AAG08097.1 - 3.3e-11 43.0 0.0 4.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4136 PF13590.6 AAG08098.1 - 2.1e-09 38.0 0.0 2.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) DUF4345 PF14248.6 AAG08099.1 - 6.5e-13 48.6 16.7 1.9e-12 47.1 17.3 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4345) DUF411 PF04214.13 AAG08100.1 - 1.1e-27 95.7 0.8 1.6e-27 95.2 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF DUF1455 PF07306.11 AAG08100.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Aminotran_1_2 PF00155.21 AAG08101.1 - 4.6e-59 200.4 0.0 5.3e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AAG08101.1 - 0.088 11.7 0.0 1 8.2 0.0 2.0 2 0 0 2 2 2 0 Allinase Beta_elim_lyase PF01212.21 AAG08101.1 - 0.096 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PM0188 PF11477.8 AAG08101.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 PhzC-PhzF PF02567.16 AAG08102.1 - 3.1e-32 112.2 0.0 5.5e-32 111.4 0.0 1.3 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Zn_peptidase PF04228.13 AAG08103.1 - 2e-136 454.1 0.9 2.3e-136 454.0 0.9 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase Peptidase_M48 PF01435.18 AAG08103.1 - 0.32 10.7 3.6 7.3 6.3 1.9 2.3 1 1 1 2 2 2 0 Peptidase family M48 LPAM_1 PF08139.12 AAG08104.1 - 0.032 14.7 3.9 0.032 14.7 3.9 2.1 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Herpes_UL42 PF02282.16 AAG08104.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.4 1 1 1 2 2 2 0 DNA polymerase processivity factor (UL42) Xan_ur_permease PF00860.20 AAG08105.1 - 4.4e-54 183.7 48.0 5.7e-54 183.3 48.0 1.1 1 0 0 1 1 1 1 Permease family DUF3333 PF11812.8 AAG08105.1 - 5.4 7.2 7.8 0.4 10.9 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) tRNA_U5-meth_tr PF05958.11 AAG08106.1 - 5.5e-171 568.3 0.0 6.2e-171 568.2 0.0 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 AAG08106.1 - 3.1e-07 31.0 0.0 6.1e-06 26.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08106.1 - 3e-06 27.1 0.0 1.1e-05 25.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08106.1 - 0.00053 20.6 0.0 0.006 17.2 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.17 AAG08106.1 - 0.0006 19.3 0.0 0.00094 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 AAG08106.1 - 0.0037 16.8 0.1 0.0062 16.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 AAG08106.1 - 0.0051 17.5 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAG08106.1 - 0.0088 15.7 0.1 0.021 14.5 0.1 1.7 1 1 0 1 1 1 1 Conserved hypothetical protein 95 DREV PF05219.12 AAG08106.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_15 PF09445.10 AAG08106.1 - 0.037 13.6 0.0 0.14 11.7 0.0 1.7 1 1 1 2 2 2 0 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 AAG08106.1 - 0.064 12.3 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 AAG08106.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 AAG08106.1 - 0.19 11.1 0.1 0.27 10.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SfsA PF03749.13 AAG08107.1 - 4e-46 156.3 0.1 5.2e-46 156.0 0.1 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 AAG08107.1 - 8.2e-22 77.1 0.0 1.8e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 SfsA N-terminal OB domain Aminotran_1_2 PF00155.21 AAG08108.1 - 7.6e-54 183.2 0.0 8.7e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AAG08108.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Allinase Beta_elim_lyase PF01212.21 AAG08108.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AAG08108.1 - 0.058 11.9 0.0 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-dskA_traR PF01258.17 AAG08109.1 - 2.1e-11 43.5 2.2 4e-11 42.6 2.2 1.5 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger CMAS PF02353.20 AAG08109.1 - 0.025 13.9 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Hpt PF01627.23 AAG08109.1 - 0.059 13.6 0.6 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 Hpt domain BTB_2 PF02214.22 AAG08109.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 BTB/POZ domain Borrelia_P83 PF05262.11 AAG08109.1 - 0.25 9.8 1.8 0.28 9.6 1.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein tRNA-synt_1c PF00749.21 AAG08110.1 - 1.6e-48 165.2 0.0 8e-30 103.8 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain HATPase_c PF02518.26 AAG08111.1 - 6.8e-24 84.5 0.0 1.8e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG08111.1 - 5.7e-12 45.5 0.0 1.8e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAG08111.1 - 3e-06 27.2 0.0 7.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAG08111.1 - 0.00034 20.8 0.0 0.00088 19.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG08111.1 - 0.00081 19.6 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAG08111.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_8 PF13188.7 AAG08111.1 - 0.0016 18.4 0.0 0.0095 15.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain HATPase_c_5 PF14501.6 AAG08111.1 - 0.0087 15.9 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAG08111.1 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 AAG08111.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain Sigma54_activat PF00158.26 AAG08112.1 - 2.3e-73 245.5 0.1 3.2e-73 245.0 0.1 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAG08112.1 - 8.3e-26 90.7 0.0 1.6e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAG08112.1 - 5.8e-22 78.0 0.1 2.2e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain AAA_5 PF07728.14 AAG08112.1 - 2.2e-08 34.2 0.1 1.7e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAG08112.1 - 8.4e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAG08112.1 - 0.00021 20.8 0.3 0.0058 16.0 0.3 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AAG08112.1 - 0.00061 19.9 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AAG08112.1 - 0.0027 18.1 2.1 0.0071 16.8 2.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain HTH_8 PF02954.19 AAG08112.1 - 0.017 14.9 1.5 0.054 13.3 0.1 2.8 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_11 PF08279.12 AAG08112.1 - 0.019 14.9 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_AsnC-type PF13404.6 AAG08112.1 - 0.05 13.4 1.3 0.15 11.9 0.1 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAG08112.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AAA_22 PF13401.6 AAG08112.1 - 0.14 12.4 0.0 0.68 10.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain HTH_Tnp_1_2 PF13022.6 AAG08112.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase PolyA_pol_arg_C PF12626.7 AAG08113.1 - 2.1e-44 150.4 3.0 3.5e-44 149.7 0.7 2.3 2 0 0 2 2 2 1 Polymerase A arginine-rich C-terminus PolyA_pol PF01743.20 AAG08113.1 - 4.3e-38 130.6 0.3 8.1e-38 129.7 0.3 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AAG08113.1 - 5.1e-21 74.2 1.5 1.2e-20 73.0 1.5 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HPPK PF01288.20 AAG08114.1 - 4.7e-36 123.7 0.0 5.5e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Pantoate_transf PF02548.15 AAG08115.1 - 2e-105 351.8 4.3 2.3e-105 351.7 4.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 AAG08115.1 - 0.00016 21.6 0.1 0.0015 18.5 0.1 2.2 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase NanE PF04131.14 AAG08115.1 - 0.033 13.4 1.8 0.14 11.3 0.2 2.3 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PEP_mutase PF13714.6 AAG08115.1 - 0.1 12.0 1.6 0.77 9.2 1.5 2.5 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Pantoate_ligase PF02569.15 AAG08116.1 - 6e-103 343.7 0.0 6.8e-103 343.5 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 AAG08116.1 - 0.074 12.5 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 ATP-sulfurylase PRP4 PF08799.11 AAG08116.1 - 0.13 11.9 3.4 1.9 8.1 0.0 3.3 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like Asp_decarbox PF02261.16 AAG08117.1 - 2e-45 153.4 0.1 2.2e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase PGI PF00342.19 AAG08118.1 - 5.4e-194 645.3 0.0 6.1e-194 645.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase AMP-binding PF00501.28 AAG08119.1 - 3.1e-91 306.1 0.0 4e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAG08119.1 - 1.1e-26 93.6 0.3 4e-24 85.4 0.1 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAG08119.1 - 4.5e-22 77.7 1.4 1.2e-21 76.4 1.4 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF2236 PF09995.9 AAG08120.1 - 1.3e-57 195.6 5.7 1.8e-57 195.2 5.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF748 PF05359.11 AAG08121.1 - 1.5e-109 362.9 7.4 7.5e-41 139.8 0.1 3.5 3 0 0 3 3 3 3 Domain of Unknown Function (DUF748) AsmA PF05170.14 AAG08121.1 - 2.6e-10 39.8 0.0 5.9e-05 22.1 0.0 3.3 3 0 0 3 3 3 3 AsmA family OmpA PF00691.20 AAG08121.1 - 6.9e-08 32.8 0.0 0.00018 21.9 0.0 2.7 2 0 0 2 2 2 2 OmpA family DUF2845 PF11006.8 AAG08122.1 - 3.6e-18 65.4 0.0 4.5e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2845) DUF2845 PF11006.8 AAG08123.1 - 1.1e-16 60.7 0.0 1.2e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2845) CsbD PF05532.12 AAG08124.1 - 3.9e-20 71.5 3.4 4.4e-20 71.3 3.4 1.0 1 0 0 1 1 1 1 CsbD-like PqqD PF05402.12 AAG08124.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.5 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) BON PF04972.17 AAG08125.1 - 1.6e-18 66.7 3.7 2.6e-18 66.1 3.7 1.3 1 0 0 1 1 1 1 BON domain YfaZ PF07437.11 AAG08125.1 - 0.023 14.3 2.5 0.64 9.6 0.2 2.1 1 1 1 2 2 2 0 YfaZ precursor HMA PF00403.26 AAG08125.1 - 0.074 13.5 4.2 0.25 11.8 1.7 2.2 1 1 1 2 2 2 0 Heavy-metal-associated domain RNase_PH PF01138.21 AAG08126.1 - 8.6e-48 162.2 0.0 1.2e-22 80.8 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 AAG08126.1 - 3.3e-23 82.0 0.1 8.8e-23 80.6 0.1 1.8 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain RNase_PH_C PF03725.15 AAG08126.1 - 1.6e-19 69.7 1.2 5.2e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 AAG08126.1 - 1e-18 67.4 4.4 4.1e-18 65.5 4.4 2.2 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 AAG08126.1 - 4.2e-13 48.9 1.8 3.3e-12 46.1 0.5 2.6 2 0 0 2 2 2 1 KH domain S1_2 PF13509.6 AAG08126.1 - 0.0094 16.0 1.0 0.046 13.8 0.3 2.6 2 1 0 2 2 2 1 S1 domain KH_2 PF07650.17 AAG08126.1 - 0.047 13.5 0.5 0.18 11.6 0.5 2.1 1 0 0 1 1 1 0 KH domain Cauli_DNA-bind PF03310.13 AAG08126.1 - 0.16 12.0 0.0 0.62 10.1 0.0 2.0 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Ribosomal_S15 PF00312.22 AAG08127.1 - 6.1e-36 122.5 0.3 6.9e-36 122.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 TruB_N PF01509.18 AAG08128.1 - 4.4e-57 192.6 0.0 5.7e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AAG08128.1 - 7.7e-21 74.0 0.2 3.3e-20 72.0 0.1 2.0 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 AAG08128.1 - 1.3e-20 73.1 0.0 2.9e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Pseudouridine synthase II TruB, C-terminal TruB_C PF09142.11 AAG08128.1 - 0.0059 16.4 0.0 0.021 14.6 0.0 2.0 1 0 0 1 1 1 1 tRNA Pseudouridine synthase II, C terminal PUA_3 PF17785.1 AAG08128.1 - 0.13 12.1 0.1 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 PUA-like domain RBFA PF02033.18 AAG08129.1 - 1.2e-32 112.5 0.0 1.3e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Ribosome-binding factor A DUF2594 PF10769.9 AAG08129.1 - 0.0051 16.8 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2594) DUF3662 PF12401.8 AAG08129.1 - 0.07 13.5 0.0 0.24 11.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2662) GTP_EFTU PF00009.27 AAG08130.1 - 7.1e-36 123.6 2.3 2.1e-34 118.8 0.4 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AAG08130.1 - 8.6e-35 119.0 0.1 2e-34 117.9 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 AAG08130.1 - 1.3e-21 76.2 1.3 2.1e-14 53.1 0.2 2.8 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region IF2_assoc PF08364.11 AAG08130.1 - 3.2e-11 43.3 13.2 3.2e-11 43.3 13.2 2.6 3 0 0 3 3 2 1 Bacterial translation initiation factor IF-2 associated region MMR_HSR1 PF01926.23 AAG08130.1 - 8e-10 38.8 0.1 1.9e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AAG08130.1 - 4.4e-08 33.4 5.2 9.5e-05 22.7 0.4 3.6 2 1 0 2 2 2 2 Elongation factor Tu domain 2 Ras PF00071.22 AAG08130.1 - 3.3e-05 23.5 0.0 8.3e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 AAG08130.1 - 8.3e-05 22.2 0.0 0.00025 20.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 AAG08130.1 - 0.00054 19.0 0.6 0.0083 15.1 0.2 2.6 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 AAG08130.1 - 0.0021 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 AAG08130.1 - 0.01 15.2 0.0 0.046 13.2 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 AAG08130.1 - 0.027 14.7 0.0 0.066 13.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 AAG08130.1 - 0.05 13.7 1.3 5 7.2 0.0 3.4 3 1 1 4 4 4 0 Dynamin family GTP_EFTU_D4 PF14578.6 AAG08130.1 - 0.16 11.9 2.5 0.55 10.2 0.3 2.7 2 0 0 2 2 2 0 Elongation factor Tu domain 4 NusA_N PF08529.11 AAG08131.1 - 5.6e-38 130.0 4.8 5.6e-38 130.0 4.8 2.3 2 0 0 2 2 2 1 NusA N-terminal domain KH_5 PF13184.6 AAG08131.1 - 4.1e-28 97.3 1.0 4.4e-26 90.7 0.2 3.4 3 0 0 3 3 3 1 NusA-like KH domain HHH_5 PF14520.6 AAG08131.1 - 1.1e-14 54.8 2.1 9.9e-10 38.9 1.2 3.2 2 0 0 2 2 2 2 Helix-hairpin-helix domain S1 PF00575.23 AAG08131.1 - 8.1e-08 32.5 0.3 8.1e-08 32.5 0.3 2.4 2 0 0 2 2 2 1 S1 RNA binding domain KH_4 PF13083.6 AAG08131.1 - 0.0034 17.2 1.2 0.016 15.0 0.0 2.8 3 0 0 3 3 3 1 KH domain RNA_pol_A_CTD PF03118.15 AAG08131.1 - 0.0094 15.7 0.2 0.34 10.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial RNA polymerase, alpha chain C terminal domain DUF4332 PF14229.6 AAG08131.1 - 0.011 16.0 0.1 0.75 10.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) DUF507 PF04368.13 AAG08131.1 - 0.024 14.6 1.5 0.024 14.6 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF507) HHH_2 PF12826.7 AAG08131.1 - 0.062 13.4 1.5 1.7 8.8 0.1 3.3 2 1 1 3 3 3 0 Helix-hairpin-helix motif S1_2 PF13509.6 AAG08131.1 - 0.075 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 S1 domain DUF2187 PF09953.9 AAG08131.1 - 0.12 12.4 3.5 0.41 10.7 0.3 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) DUF150 PF02576.17 AAG08132.1 - 1.1e-31 109.1 0.4 1.9e-31 108.3 0.1 1.6 2 0 0 2 2 2 1 RimP N-terminal domain DUF150_C PF17384.2 AAG08132.1 - 1.2e-20 73.4 0.0 1.7e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain LSM PF01423.22 AAG08132.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 LSM domain SecG PF03840.14 AAG08133.1 - 5.2e-20 71.3 9.5 7e-20 70.9 9.5 1.2 1 0 0 1 1 1 1 Preprotein translocase SecG subunit TIM PF00121.18 AAG08134.1 - 1.6e-82 276.6 0.0 1.8e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PGM_PMM_I PF02878.16 AAG08135.1 - 4.8e-44 149.4 0.0 9.7e-44 148.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AAG08135.1 - 1.2e-30 106.0 0.1 1.9e-30 105.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AAG08135.1 - 3.2e-19 69.5 0.0 6.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AAG08135.1 - 6.6e-12 45.4 0.4 1.8e-11 44.0 0.4 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2713 PF10897.8 AAG08135.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Pterin_bind PF00809.22 AAG08136.1 - 2.9e-85 285.8 0.0 3.4e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 Pterin binding enzyme Peptidase_M41 PF01434.18 AAG08137.1 - 8e-73 244.4 0.1 1.2e-72 243.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AAG08137.1 - 5e-46 156.4 0.0 1.1e-45 155.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 AAG08137.1 - 2.2e-13 50.5 0.7 1.3e-12 48.0 0.2 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_lid_3 PF17862.1 AAG08137.1 - 1.4e-11 44.0 0.0 2.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 AAG08137.1 - 1.4e-06 28.4 0.0 1.3e-05 25.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AAG08137.1 - 1.4e-05 24.5 0.0 3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 AAG08137.1 - 0.00027 20.7 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AAG08137.1 - 0.0007 20.0 0.6 0.031 14.7 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 AAG08137.1 - 0.002 18.3 0.0 0.005 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG08137.1 - 0.0036 17.6 0.1 0.17 12.2 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 AAG08137.1 - 0.0043 17.2 0.2 0.016 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AAG08137.1 - 0.0043 16.5 0.2 0.0099 15.3 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AAG08137.1 - 0.0071 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 AAG08137.1 - 0.086 13.4 0.1 0.26 11.8 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_17 PF13207.6 AAG08137.1 - 0.11 13.0 0.0 0.35 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAG08137.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAG08137.1 - 0.12 11.9 0.2 0.39 10.2 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 AAG08137.1 - 0.13 11.7 0.2 0.26 10.7 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF1128 PF06569.11 AAG08137.1 - 0.16 12.0 0.4 0.39 10.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) NACHT PF05729.12 AAG08137.1 - 0.21 11.5 0.0 0.5 10.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Tetrabrachion PF11401.8 AAG08137.1 - 0.53 10.3 2.3 0.64 10.1 0.3 2.1 2 0 0 2 2 2 0 Tetrabrachion FtsJ PF01728.19 AAG08138.1 - 1.8e-56 191.0 0.0 2.1e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 AAG08138.1 - 0.00038 20.3 0.0 0.004 17.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08138.1 - 0.069 13.9 0.2 1.5 9.6 0.2 2.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 AAG08138.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 AAG08138.1 - 0.21 11.2 0.0 0.57 9.8 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F CRS1_YhbY PF01985.21 AAG08139.1 - 1.9e-19 69.6 0.2 2.2e-19 69.4 0.2 1.0 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain DUF4149 PF13664.6 AAG08140.1 - 2.6e-05 24.5 6.8 2.6e-05 24.5 6.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4149) GreA_GreB_N PF03449.15 AAG08141.1 - 1.2e-29 102.2 1.6 1.7e-29 101.8 1.6 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AAG08141.1 - 1.7e-28 98.3 1.0 2.8e-28 97.6 1.0 1.4 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DDR_swiveling PF18427.1 AAG08141.1 - 0.0059 16.6 0.5 0.015 15.3 0.1 1.8 1 1 1 2 2 2 1 DD-reactivating factor swiveling domain Inhibitor_I24 PF10465.9 AAG08141.1 - 0.031 14.3 0.1 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 PinA peptidase inhibitor FlxA PF14282.6 AAG08141.1 - 0.1 12.6 0.4 0.16 12.0 0.4 1.2 1 0 0 1 1 1 0 FlxA-like protein CPSase_L_D2 PF02786.17 AAG08142.1 - 7.4e-108 358.9 0.6 1.6e-72 243.5 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AAG08142.1 - 6e-41 139.6 0.2 1.4e-40 138.4 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 AAG08142.1 - 4e-20 71.8 0.1 2.4e-19 69.3 0.1 2.4 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 AAG08142.1 - 5.1e-18 65.2 0.1 5.2e-12 45.7 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 AAG08142.1 - 1.9e-12 47.5 0.1 8.4e-08 32.4 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAG08142.1 - 1.1e-09 38.1 0.0 1.2e-05 25.0 0.1 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 AAG08142.1 - 8e-09 35.3 0.0 7.3e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 AAG08142.1 - 3.4e-08 33.2 0.0 0.0087 15.7 0.0 4.0 3 1 0 3 3 3 2 ATP-grasp domain RimK PF08443.11 AAG08142.1 - 0.00029 20.5 0.0 1.3 8.6 0.0 3.2 4 0 0 4 4 4 2 RimK-like ATP-grasp domain CoA_binding_2 PF13380.6 AAG08142.1 - 0.0032 18.0 0.3 3.1 8.3 0.0 4.0 4 1 0 4 4 4 1 CoA binding domain ATP-grasp_5 PF13549.6 AAG08142.1 - 0.013 14.9 0.0 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain LysE PF01810.18 AAG08143.1 - 4.5e-57 192.6 12.6 5.3e-57 192.4 12.6 1.0 1 0 0 1 1 1 1 LysE type translocator CPSase_sm_chain PF00988.22 AAG08144.1 - 4.4e-52 175.3 0.0 6.6e-52 174.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AAG08144.1 - 7.3e-47 159.6 0.0 1.1e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAG08144.1 - 2.5e-07 30.7 0.0 8.2e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AAG08144.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DapB_C PF05173.14 AAG08145.1 - 5.2e-44 149.2 0.1 7.5e-44 148.6 0.1 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 AAG08145.1 - 6.2e-41 139.4 0.9 1.6e-39 134.9 0.1 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 AAG08145.1 - 0.29 11.4 1.7 0.92 9.8 0.4 2.4 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DnaJ_C PF01556.18 AAG08146.1 - 1.2e-44 152.0 0.0 1.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AAG08146.1 - 3.1e-28 97.7 1.1 4.7e-28 97.1 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AAG08146.1 - 3.6e-14 52.9 18.9 6e-14 52.1 18.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AAG08146.1 - 0.00076 19.4 17.7 0.043 13.8 5.1 2.8 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein SCP_3 PF17844.1 AAG08146.1 - 0.019 14.7 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial SCP ortholog LprI PF07007.12 AAG08146.1 - 0.08 13.6 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Lysozyme inhibitor LprI Cytochrome_CBB3 PF13442.6 AAG08146.1 - 0.35 11.2 5.3 6.1 7.2 0.4 2.8 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III zf-RING_10 PF16685.5 AAG08146.1 - 0.92 9.7 3.2 0.72 10.0 1.3 1.8 1 1 1 2 2 2 0 zinc RING finger of MSL2 Cytochrome_C7 PF14522.6 AAG08146.1 - 1.3 9.0 8.5 13 5.9 8.5 2.3 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 AAG08146.1 - 2.5 8.6 6.3 4.7 7.7 0.2 2.4 1 1 1 2 2 2 0 Cytochrome c3 zinc-ribbons_6 PF07191.12 AAG08146.1 - 3.2 7.8 6.3 6.2 6.9 6.3 1.5 1 0 0 1 1 1 0 zinc-ribbons RseC_MucC PF04246.12 AAG08146.1 - 6 6.8 5.5 3 7.8 0.8 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC HSP70 PF00012.20 AAG08147.1 - 6.7e-265 879.9 17.0 7.7e-265 879.7 17.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AAG08147.1 - 1.1e-15 57.3 3.5 4.7e-13 48.7 0.5 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 AAG08147.1 - 3.9e-05 23.5 0.0 8.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 AAG08147.1 - 0.00057 19.2 0.7 0.0066 15.8 0.1 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.6 AAG08147.1 - 0.062 13.7 9.9 1.3 9.5 0.2 4.0 3 2 0 3 3 3 0 Cell division protein FtsA GrpE PF01025.19 AAG08148.1 - 9.4e-52 175.0 1.2 1.1e-51 174.8 1.2 1.0 1 0 0 1 1 1 1 GrpE Exonuc_VII_L PF02601.15 AAG08148.1 - 0.022 14.4 0.7 0.028 14.0 0.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bacillus_HBL PF05791.11 AAG08148.1 - 0.14 11.9 0.7 0.19 11.5 0.7 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CLZ PF16526.5 AAG08148.1 - 0.64 10.4 6.8 0.22 11.9 3.7 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 AAG08148.1 - 0.68 8.4 6.3 0.66 8.4 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SMC_N PF02463.19 AAG08149.1 - 4.1e-16 59.1 0.0 1.6e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG08149.1 - 4.8e-12 46.8 3.7 4.3e-11 43.7 3.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG08149.1 - 6e-05 22.7 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG08149.1 - 0.0054 16.7 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase NTPase_P4 PF11602.8 AAG08149.1 - 0.0064 15.8 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 ATPase P4 of dsRNA bacteriophage phi-12 AAA_22 PF13401.6 AAG08149.1 - 0.0082 16.4 8.5 0.11 12.8 0.0 4.1 4 1 1 5 5 5 1 AAA domain AAA_21 PF13304.6 AAG08149.1 - 0.052 13.4 0.0 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AAG08149.1 - 0.086 13.4 4.8 1.6 9.2 2.8 3.6 2 1 0 2 2 2 0 ABC transporter GyrI-like PF06445.15 AAG08149.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.6 2 0 0 2 2 2 0 GyrI-like small molecule binding domain V_ATPase_I PF01496.19 AAG08149.1 - 2.1 6.2 6.6 0.19 9.6 1.0 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF87 PF01935.17 AAG08149.1 - 7.3 6.6 6.7 55 3.7 0.1 2.9 2 1 0 2 2 2 0 Helicase HerA, central domain T2SSF PF00482.23 AAG08149.1 - 8.7 6.3 7.9 1.2 9.1 2.5 2.5 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F FUR PF01475.19 AAG08150.1 - 1.3e-45 154.4 0.1 1.5e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_Tnp_Tc3_2 PF01498.18 AAG08150.1 - 0.00088 19.5 0.0 0.065 13.5 0.0 2.3 1 1 1 2 2 2 1 Transposase PadR PF03551.14 AAG08150.1 - 0.0033 17.3 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_12 PF08461.10 AAG08150.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_20 PF12840.7 AAG08150.1 - 0.036 14.1 0.3 0.093 12.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Replic_Relax PF13814.6 AAG08150.1 - 0.044 13.8 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation HOIP-UBA PF16678.5 AAG08150.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair SmpA_OmlA PF04355.13 AAG08151.1 - 1.1e-25 89.2 0.0 2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 SmpA / OmlA family Ub-RnfH PF03658.14 AAG08152.1 - 1.1e-30 105.9 0.0 1.2e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 RnfH family Ubiquitin Polyketide_cyc PF03364.20 AAG08153.1 - 8.2e-35 119.8 0.0 9.3e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AAG08153.1 - 1.8e-09 38.0 0.0 1.9e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Inh PF02974.14 AAG08153.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protease inhibitor Inh SmpB PF01668.18 AAG08154.1 - 1.8e-58 196.5 0.2 2.1e-58 196.3 0.2 1.0 1 0 0 1 1 1 1 SmpB protein FCD PF07729.12 AAG08155.1 - 6.9e-27 94.3 9.6 6.9e-27 94.3 9.6 1.8 3 0 0 3 3 1 1 FCD domain GntR PF00392.21 AAG08155.1 - 2.1e-22 78.6 0.3 5e-22 77.3 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAG08155.1 - 0.00048 20.0 1.4 0.0017 18.2 0.1 2.5 2 1 0 2 2 2 1 MarR family Rrf2 PF02082.20 AAG08155.1 - 0.0027 18.0 0.1 0.0073 16.6 0.1 1.8 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 AAG08155.1 - 0.0051 16.3 0.5 0.019 14.5 0.0 2.2 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding PaaX PF07848.12 AAG08155.1 - 0.0093 16.2 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 PaaX-like protein HTH_28 PF13518.6 AAG08155.1 - 0.015 15.4 0.3 0.066 13.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 AAG08155.1 - 0.016 15.2 0.9 4.9 7.3 0.4 3.3 2 1 1 3 3 3 0 HTH domain TrmB PF01978.19 AAG08155.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AAG08155.1 - 0.019 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAG08155.1 - 0.026 14.4 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 AAG08155.1 - 0.039 13.9 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 AAG08155.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR PF01047.22 AAG08155.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 AAG08155.1 - 0.089 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Cas9-BH PF16593.5 AAG08155.1 - 1.5 8.6 7.6 47 3.8 6.9 2.7 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 DUF1771 PF08590.10 AAG08155.1 - 4 7.9 12.1 0.44 11.0 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Lactate_perm PF02652.14 AAG08156.1 - 1.2e-203 677.6 44.1 1.4e-203 677.4 44.1 1.0 1 0 0 1 1 1 1 L-lactate permease WAPL PF07814.13 AAG08156.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin FMN_dh PF01070.18 AAG08157.1 - 1.5e-125 418.8 0.0 1.8e-125 418.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AAG08157.1 - 2.3e-06 26.9 1.7 1.5e-05 24.2 0.8 2.5 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 AAG08157.1 - 0.00015 21.3 2.9 0.00015 21.3 2.9 1.4 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.17 AAG08157.1 - 0.00019 20.7 0.9 0.00031 20.0 0.9 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 AAG08157.1 - 0.0016 17.8 0.5 0.49 9.6 0.5 2.5 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IGPS PF00218.21 AAG08157.1 - 0.0043 16.3 0.0 0.0073 15.5 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase DHO_dh PF01180.21 AAG08157.1 - 0.048 12.9 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AAG08157.1 - 0.11 12.0 0.2 1.1 8.7 0.1 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein FAD-oxidase_C PF02913.19 AAG08158.1 - 1.1e-62 211.9 0.0 2e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAG08158.1 - 2.5e-33 114.8 0.1 4.5e-33 113.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 AAG08158.1 - 1.2e-09 38.6 3.2 2.8e-09 37.4 3.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG08158.1 - 1.7e-09 38.0 1.4 4.1e-09 36.8 1.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG08158.1 - 6.7e-09 36.2 2.1 1.4e-08 35.1 2.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain CCG PF02754.16 AAG08158.1 - 6.2e-07 29.5 9.3 0.0063 16.7 0.0 4.3 5 0 0 5 5 5 2 Cysteine-rich domain Fer4_16 PF13484.6 AAG08158.1 - 1.5e-05 25.8 2.6 3.1e-05 24.8 2.6 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AAG08158.1 - 0.00018 21.6 4.6 0.00066 19.7 4.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG08158.1 - 0.00026 21.1 3.3 0.00071 19.7 3.3 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAG08158.1 - 0.00029 20.5 11.6 0.00052 19.7 3.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 AAG08158.1 - 0.0093 16.0 3.1 0.03 14.4 3.1 1.8 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_4 PF12800.7 AAG08158.1 - 0.015 15.7 2.3 0.015 15.7 2.3 2.2 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_21 PF14697.6 AAG08158.1 - 0.06 13.5 8.8 0.85 9.8 8.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAG08158.1 - 0.092 12.9 1.4 7.8 6.7 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAG08158.1 - 0.44 10.7 10.5 0.023 14.8 3.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAG08158.1 - 0.54 11.3 12.1 4.6 8.4 4.4 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain AdoMet_dc PF02675.15 AAG08159.1 - 2.6e-34 117.6 0.0 3.1e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Spermine_synth PF01564.17 AAG08160.1 - 8.1e-39 133.0 0.0 1.2e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 AAG08160.1 - 2e-09 37.2 0.0 3.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 AAG08160.1 - 4.3e-06 27.4 0.0 8.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08160.1 - 0.00087 20.0 0.0 0.002 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AAG08160.1 - 0.044 14.8 0.6 0.14 13.2 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 AAG08160.1 - 0.061 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Response_reg PF00072.24 AAG08162.1 - 2.6e-23 82.3 0.0 3.7e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG08162.1 - 6e-23 80.7 0.1 1.2e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF1598 PF07643.11 AAG08162.1 - 0.19 12.0 0.1 0.74 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) HATPase_c PF02518.26 AAG08163.1 - 9.4e-22 77.6 0.0 1.8e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG08163.1 - 1.2e-09 38.0 2.4 1.2e-09 38.0 2.4 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAG08163.1 - 0.00032 20.7 0.0 0.00075 19.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain 2CSK_N PF08521.10 AAG08163.1 - 0.00081 19.5 0.0 0.0025 17.9 0.0 1.9 1 1 0 1 1 1 1 Two-component sensor kinase N-terminal HPTransfase PF10090.9 AAG08163.1 - 0.052 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 AAG08163.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MerR-DNA-bind PF09278.11 AAG08164.1 - 1.7e-21 76.5 4.1 2.7e-21 75.8 4.1 1.3 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 AAG08164.1 - 2.7e-17 62.6 0.0 4.9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAG08164.1 - 4.3e-16 58.4 0.4 7.3e-16 57.7 0.4 1.4 1 0 0 1 1 1 1 MerR family regulatory protein Death PF00531.22 AAG08164.1 - 0.0035 17.5 0.3 0.0084 16.3 0.2 1.8 1 1 0 1 1 1 1 Death domain DivIVA PF05103.13 AAG08164.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 DivIVA protein OmpH PF03938.14 AAG08164.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) EamA PF00892.20 AAG08165.1 - 2.3e-31 108.8 42.8 1.7e-17 63.8 17.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 AAG08165.1 - 0.0014 17.8 6.5 0.0097 15.0 2.6 2.7 2 1 0 2 2 2 2 Magnesium transporter NIPA PUNUT PF16913.5 AAG08165.1 - 0.0089 15.3 1.1 0.016 14.5 1.1 1.5 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport RIO1 PF01163.22 AAG08166.1 - 9.4e-48 162.3 0.0 1.3e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AAG08166.1 - 0.0026 17.7 16.9 0.0086 16.0 3.9 3.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 AAG08166.1 - 0.0031 17.1 0.0 0.022 14.3 0.0 2.1 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 AAG08166.1 - 0.0069 15.8 0.5 0.09 12.1 0.4 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Response_reg PF00072.24 AAG08167.1 - 4.3e-26 91.3 0.0 8.1e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HD_5 PF13487.6 AAG08167.1 - 4.2e-18 65.3 0.3 6e-17 61.7 0.0 2.9 3 0 0 3 3 3 1 HD domain HD PF01966.22 AAG08167.1 - 1.9e-16 60.4 1.0 2.8e-16 59.9 0.3 1.7 2 0 0 2 2 2 1 HD domain PEP-utilisers_N PF05524.13 AAG08167.1 - 0.054 13.7 2.6 6.9 6.9 0.0 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal EamA PF00892.20 AAG08169.1 - 1.1e-34 119.5 36.0 4.9e-18 65.6 13.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family HTH_24 PF13412.6 AAG08170.1 - 1.3e-16 59.9 0.0 3.5e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAG08170.1 - 3.6e-16 58.7 0.4 8.5e-16 57.5 0.4 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 AAG08170.1 - 2.2e-12 46.8 0.0 4e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain MarR_2 PF12802.7 AAG08170.1 - 6.5e-09 35.5 0.4 1.4e-08 34.4 0.2 1.6 2 0 0 2 2 1 1 MarR family MarR PF01047.22 AAG08170.1 - 7.2e-06 25.8 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAG08170.1 - 2.2e-05 24.4 0.5 0.00011 22.2 0.1 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 AAG08170.1 - 0.00038 20.5 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DprA_WH PF17782.1 AAG08170.1 - 0.0016 18.5 0.1 0.0052 16.9 0.0 1.9 2 0 0 2 2 1 1 DprA winged helix domain HTH_5 PF01022.20 AAG08170.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AAG08170.1 - 0.0018 18.1 0.0 0.0055 16.6 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AAG08170.1 - 0.0025 17.6 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_1 PF00126.27 AAG08170.1 - 0.0034 17.3 0.1 0.007 16.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 AAG08170.1 - 0.0037 17.2 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_9 PF08221.11 AAG08170.1 - 0.0062 16.6 0.0 0.018 15.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_Mga PF08280.11 AAG08170.1 - 0.0073 16.3 0.0 0.047 13.7 0.0 2.1 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain Fe_dep_repress PF01325.19 AAG08170.1 - 0.0079 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 AAG08170.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain BRICHOS PF04089.14 AAG08170.1 - 0.024 14.8 0.0 0.053 13.8 0.0 1.5 2 0 0 2 2 2 0 BRICHOS domain Rrf2 PF02082.20 AAG08170.1 - 0.03 14.7 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_34 PF13601.6 AAG08170.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_38 PF13936.6 AAG08170.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AAG08170.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Thiolase_N PF00108.23 AAG08171.1 - 2.1e-46 158.4 0.0 3.7e-46 157.6 0.0 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAG08171.1 - 8e-30 103.0 0.0 1.4e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAG08171.1 - 0.0023 17.6 0.1 0.0086 15.7 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.6 AAG08172.1 - 7.2e-52 176.3 2.0 3.3e-50 170.8 1.9 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG08172.1 - 2.7e-40 137.9 0.5 7.4e-40 136.5 0.6 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 AAG08172.1 - 1.1e-17 64.5 1.4 1.1e-17 64.5 1.4 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 AAG08172.1 - 7.6e-08 32.1 0.1 2.3e-07 30.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 AAG08172.1 - 0.0018 18.5 0.2 0.0081 16.4 0.1 2.1 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Arabinose_bd PF12625.7 AAG08173.1 - 2e-41 142.1 1.7 2e-41 142.1 1.7 2.0 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG08173.1 - 5.7e-18 65.0 0.5 1.8e-17 63.4 0.5 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG08173.1 - 5.2e-08 32.8 0.0 1.1e-06 28.6 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAG08173.1 - 0.0064 16.3 2.0 0.37 10.7 0.3 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 AAG08173.1 - 0.039 14.0 0.3 0.45 10.6 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn helix DprA_WH PF17782.1 AAG08173.1 - 0.057 13.5 2.8 9.2 6.5 0.2 3.0 3 0 0 3 3 3 0 DprA winged helix domain HTH_20 PF12840.7 AAG08173.1 - 0.79 9.8 4.8 1.9 8.6 0.2 2.7 1 1 1 2 2 2 0 Helix-turn-helix domain MaoC_dehydratas PF01575.19 AAG08174.1 - 7.6e-13 48.1 0.0 2e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAG08174.1 - 0.00099 19.3 0.4 1.5 9.0 0.0 2.7 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase PP2C_2 PF13672.6 AAG08174.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C MazG-like PF12643.7 AAG08175.1 - 1.7e-07 31.4 0.1 2e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 AAG08175.1 - 0.0014 18.7 0.1 0.002 18.3 0.1 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF3379 PF11859.8 AAG08175.1 - 0.015 14.6 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Methyltransf_23 PF13489.6 AAG08176.1 - 7.5e-15 55.1 0.0 9.4e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08176.1 - 2.6e-14 53.7 0.0 7.5e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08176.1 - 1.9e-13 50.9 0.0 3.2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08176.1 - 1.6e-12 48.0 0.0 2.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08176.1 - 2.5e-11 43.6 0.0 3.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG08176.1 - 2.3e-05 24.0 0.0 3.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 AAG08176.1 - 0.00012 23.1 0.0 0.0047 17.9 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain TehB PF03848.14 AAG08176.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 AAG08176.1 - 0.037 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.20 AAG08176.1 - 0.038 13.1 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.12 AAG08176.1 - 0.05 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 AAG08176.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4136 PF13590.6 AAG08177.1 - 8.7e-19 68.4 0.1 1.1e-18 68.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) LptE PF04390.12 AAG08177.1 - 0.00099 19.8 0.0 0.0014 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide-assembly DUF799 PF05643.11 AAG08177.1 - 0.0022 17.6 0.1 0.0031 17.2 0.1 1.1 1 0 0 1 1 1 1 Putative bacterial lipoprotein (DUF799) GDPD PF03009.17 AAG08178.1 - 1.4e-17 64.3 0.0 6.5e-17 62.1 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EAL PF00563.20 AAG08178.1 - 0.032 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 EAL domain DUF4136 PF13590.6 AAG08179.1 - 5.3e-30 104.7 0.2 6.7e-30 104.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) Acetyltransf_1 PF00583.25 AAG08180.1 - 4.6e-11 43.0 0.1 5.7e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG08180.1 - 3.9e-07 30.4 0.1 5e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG08180.1 - 7.4e-07 29.2 0.0 8.9e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG08180.1 - 0.00012 21.9 0.3 0.0035 17.3 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 AAG08180.1 - 0.0013 19.5 0.0 0.0016 19.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG08180.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 AAG08180.1 - 0.033 13.9 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DrsE PF02635.15 AAG08181.1 - 1.2e-15 57.9 0.0 1.4e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 AAG08181.1 - 0.00079 19.3 0.0 0.9 9.4 0.0 2.1 1 1 1 2 2 2 2 DsrE/DsrF/DrsH-like family Herpes_UL55 PF04537.12 AAG08181.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL55 protein GCV_H PF01597.19 AAG08182.1 - 3.5e-24 85.0 0.0 4e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Transposase_20 PF02371.16 AAG08183.1 - 7.2e-25 87.1 0.7 1.9e-24 85.8 0.7 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAG08183.1 - 5.4e-15 55.6 0.2 2.4e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 Transposase Cep57_MT_bd PF06657.13 AAG08183.1 - 0.0024 18.3 0.5 0.0056 17.1 0.1 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 HHH PF00633.23 AAG08183.1 - 0.02 14.7 0.1 0.063 13.2 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lzipper-MIP1 PF14389.6 AAG08183.1 - 0.021 15.1 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_transf_4 PF13439.6 AAG08183.1 - 0.054 13.5 0.4 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HalX PF08663.10 AAG08183.1 - 0.095 13.0 1.6 0.33 11.3 1.6 1.9 1 0 0 1 1 1 0 HalX domain DUF3287 PF11690.8 AAG08183.1 - 0.11 12.2 0.6 0.31 10.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ABC_tran_CTD PF16326.5 AAG08183.1 - 0.12 12.6 1.5 0.25 11.6 1.5 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AAG08183.1 - 0.4 10.8 3.0 0.23 11.5 0.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation GrpB PF04229.14 AAG08184.1 - 4.2e-49 166.8 0.0 5.3e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 GrpB protein AAA_33 PF13671.6 AAG08185.1 - 2.2e-06 27.9 0.0 3.7e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 AAG08185.1 - 0.00018 21.7 0.0 0.0059 16.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_28 PF13521.6 AAG08185.1 - 0.0002 21.7 0.7 0.00062 20.0 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAG08185.1 - 0.00026 21.6 0.0 0.00036 21.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAG08185.1 - 0.0033 17.9 0.0 0.0077 16.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 AAG08185.1 - 0.0054 16.0 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 AAG08185.1 - 0.013 16.0 0.0 0.03 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAG08185.1 - 0.017 14.9 0.2 0.07 12.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG08185.1 - 0.02 15.3 0.3 0.044 14.2 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 AAG08185.1 - 0.052 13.6 0.9 0.092 12.8 0.9 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IIGP PF05049.13 AAG08185.1 - 0.053 12.6 0.0 0.072 12.1 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RNA_helicase PF00910.22 AAG08185.1 - 0.055 13.9 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 AAG08185.1 - 0.055 13.2 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase MMR_HSR1 PF01926.23 AAG08185.1 - 0.07 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAG08185.1 - 0.083 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 AAG08185.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 AAG08185.1 - 0.14 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Septin NACHT PF05729.12 AAG08185.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 AAG08185.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PRK PF00485.18 AAG08185.1 - 0.2 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Herpes_Helicase PF02689.14 AAG08185.1 - 0.23 9.3 0.1 0.29 9.0 0.1 1.1 1 0 0 1 1 1 0 Helicase Methyltransf_11 PF08241.12 AAG08186.1 - 3.2e-15 56.6 0.0 4.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08186.1 - 1e-13 51.8 0.0 1.6e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08186.1 - 4.5e-12 46.6 0.0 7.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08186.1 - 2.3e-10 40.5 0.0 3.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAG08186.1 - 2.8e-07 30.1 0.0 3.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AAG08186.1 - 6.5e-07 29.3 0.0 9.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AAG08186.1 - 0.00014 20.9 0.0 0.00016 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CN_hydrolase PF00795.22 AAG08188.1 - 9e-24 84.2 0.0 1.1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_11 PF08241.12 AAG08189.1 - 3.9e-12 46.7 0.1 5.6e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08189.1 - 4.9e-12 46.4 0.1 8e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08189.1 - 4.2e-10 40.2 0.0 6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AAG08189.1 - 4.8e-06 26.3 0.0 6.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 AAG08189.1 - 6.9e-06 25.5 0.1 9.4e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 AAG08189.1 - 0.00032 20.1 0.0 0.00041 19.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 AAG08189.1 - 0.00049 19.8 0.0 0.00075 19.2 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 AAG08189.1 - 0.0018 18.1 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG08189.1 - 0.057 13.0 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AA_permease_2 PF13520.6 AAG08190.1 - 3.5e-52 177.7 32.7 4.1e-52 177.5 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAG08190.1 - 7.2e-31 107.3 30.9 9.1e-31 107.0 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease TssN PF17555.2 AAG08190.1 - 2.3 7.5 5.2 4.5 6.6 0.1 2.6 2 0 0 2 2 2 0 Type VI secretion system, TssN Aminotran_3 PF00202.21 AAG08191.1 - 4.5e-83 279.2 0.0 5.3e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III GerE PF00196.19 AAG08192.1 - 1.4e-12 47.0 0.0 2.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 AAG08192.1 - 0.053 13.7 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAG08192.1 - 0.057 12.8 1.0 0.29 10.6 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 AAG08192.1 - 0.27 10.8 2.4 1.5 8.4 0.1 3.2 3 1 0 3 3 3 0 Sigma-70, region 4 GTP_EFTU PF00009.27 AAG08193.1 - 7.2e-32 110.5 0.0 3.4e-31 108.3 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SelB-wing_3 PF09107.11 AAG08193.1 - 2.7e-18 65.3 1.9 2.7e-18 65.3 1.9 2.2 2 0 0 2 2 2 1 Elongation factor SelB, winged helix SelB-wing_2 PF09106.11 AAG08193.1 - 4.4e-15 55.6 0.9 4.4e-15 55.6 0.9 3.7 2 1 1 3 3 3 1 Elongation factor SelB, winged helix GTP_EFTU_D2 PF03144.25 AAG08193.1 - 7.5e-07 29.5 0.0 1.8e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAG08193.1 - 1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 AAG08193.1 - 0.017 14.9 0.0 0.078 12.7 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.6 AAG08193.1 - 0.028 14.3 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SRPRB PF09439.10 AAG08193.1 - 0.043 13.2 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SelA PF03841.13 AAG08194.1 - 4.6e-170 565.5 0.0 5.5e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Se-cys_synth_N PF12390.8 AAG08194.1 - 1.7e-08 34.5 6.5 1.7e-08 34.5 6.5 3.7 3 0 0 3 3 3 1 Selenocysteine synthase N terminal DegT_DnrJ_EryC1 PF01041.17 AAG08194.1 - 0.0053 16.1 0.3 0.046 13.0 0.3 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAG08194.1 - 0.017 13.7 0.0 0.035 12.6 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAG08194.1 - 0.029 13.3 0.0 0.074 12.0 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAG08194.1 - 0.079 12.2 0.1 1.2 8.4 0.0 2.9 2 1 0 2 2 2 0 Beta-eliminating lyase FdhE PF04216.12 AAG08195.1 - 2.4e-97 326.3 0.1 2.7e-97 326.1 0.1 1.0 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation TSKS PF15358.6 AAG08195.1 - 0.02 13.3 0.2 0.031 12.7 0.2 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate zf-ribbon_3 PF13248.6 AAG08195.1 - 0.049 13.0 4.4 1.9 8.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-TFIIB PF13453.6 AAG08195.1 - 1 8.7 5.5 9.4 5.7 0.2 2.8 3 0 0 3 3 3 0 Transcription factor zinc-finger DnaJ_CXXCXGXG PF00684.19 AAG08195.1 - 1.4 9.4 6.4 29 5.1 0.0 2.3 2 0 0 2 2 2 0 DnaJ central domain Zn-ribbon_8 PF09723.10 AAG08195.1 - 3.4 7.9 9.1 2.6 8.2 0.1 2.8 2 1 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 AAG08195.1 - 9.2 6.1 7.4 6 6.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Ni_hydr_CYTB PF01292.20 AAG08196.1 - 5e-21 75.1 17.9 6e-21 74.9 17.9 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AAG08196.1 - 2.9e-07 30.9 15.1 2.9e-07 30.9 15.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4405) DUF2304 PF10066.9 AAG08196.1 - 0.029 14.6 0.3 0.029 14.6 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF4234 PF14018.6 AAG08196.1 - 0.15 12.2 4.7 12 6.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) DUF2721 PF11026.8 AAG08196.1 - 0.31 10.9 12.1 3.5 7.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Acyl_transf_3 PF01757.22 AAG08196.1 - 0.34 9.9 19.1 0.56 9.2 19.0 1.4 1 1 0 1 1 1 0 Acyltransferase family DUF4131 PF13567.6 AAG08196.1 - 0.55 9.9 15.3 0.048 13.3 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4079 PF13301.6 AAG08196.1 - 0.75 10.0 13.4 1.4 9.0 7.9 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF4079) DUF418 PF04235.12 AAG08196.1 - 1 9.3 14.0 0.14 12.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF418) Fer4_11 PF13247.6 AAG08197.1 - 1.6e-24 85.9 8.2 1.6e-24 85.9 8.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Form-deh_trans PF09163.11 AAG08197.1 - 2.1e-23 81.8 0.0 3.8e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Formate dehydrogenase N, transmembrane Fer4_7 PF12838.7 AAG08197.1 - 3.4e-16 59.6 22.0 1.3e-09 38.4 5.3 3.4 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG08197.1 - 2.1e-12 47.0 21.3 5.5e-06 26.5 9.2 2.7 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG08197.1 - 6.7e-12 45.3 27.2 7.7e-06 25.9 10.9 3.6 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG08197.1 - 1.5e-10 40.7 34.2 8.1e-06 25.7 3.2 4.7 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_2 PF12797.7 AAG08197.1 - 3.7e-09 36.1 29.5 5e-05 23.1 1.3 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4 PF00037.27 AAG08197.1 - 8.2e-09 34.9 39.4 1.6e-06 27.7 3.4 5.2 6 0 0 6 6 5 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAG08197.1 - 1.1e-07 31.9 27.2 2.9e-06 27.3 8.1 3.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG08197.1 - 2.2e-05 24.6 31.2 0.0063 16.9 2.6 4.4 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAG08197.1 - 0.00024 21.8 38.8 0.33 12.0 2.9 4.4 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_15 PF13459.6 AAG08197.1 - 0.00031 21.4 12.3 0.13 13.0 0.3 3.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_8 PF13183.6 AAG08197.1 - 0.00051 20.4 28.5 0.0099 16.3 8.6 3.8 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG08197.1 - 0.00098 20.0 27.7 0.27 12.2 0.0 4.7 2 1 4 6 6 6 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AAG08197.1 - 0.02 15.4 29.3 0.62 10.6 2.7 4.5 1 1 4 6 6 6 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAG08197.1 - 0.038 14.8 1.5 0.038 14.8 1.5 3.7 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAG08197.1 - 0.1 12.4 0.3 0.1 12.4 0.3 4.1 2 1 2 4 4 4 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_13 PF13370.6 AAG08197.1 - 0.15 12.6 0.6 0.15 12.6 0.6 4.2 3 1 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AAG08197.1 - 1.4 9.1 21.5 5.7 7.2 9.3 3.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Abhydrolase_1 PF00561.20 AAG08198.1 - 1.1e-16 61.3 0.0 2.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 AAG08198.1 - 7.4e-09 35.8 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 AAG08198.1 - 0.00014 21.7 0.1 0.00022 21.0 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 AAG08198.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 AAG08198.1 - 0.00056 20.6 1.9 0.00073 20.2 1.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 AAG08198.1 - 0.0037 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 AAG08198.1 - 0.0047 16.1 0.0 0.0061 15.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase UPF0227 PF05728.12 AAG08198.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 AAG08198.1 - 0.21 10.9 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Oxidored_FMN PF00724.20 AAG08199.1 - 3e-73 247.1 0.0 3.9e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AAG08199.1 - 3.5e-21 75.7 0.0 5.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG08199.1 - 4.5e-09 36.7 2.8 4.3e-05 24.0 0.2 3.7 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG08199.1 - 3.4e-08 33.6 0.1 3.4e-08 33.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAG08199.1 - 3.6e-07 29.2 0.5 7.9e-07 28.1 0.5 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 AAG08199.1 - 1e-06 28.4 0.2 1.6e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAG08199.1 - 1.7e-05 24.3 1.2 0.11 11.7 0.5 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG08199.1 - 1.8e-05 24.1 1.7 1.8e-05 24.1 1.7 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 AAG08199.1 - 0.00013 21.3 0.8 0.00054 19.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 AAG08199.1 - 0.00015 20.9 0.2 0.0003 20.0 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 AAG08199.1 - 0.00098 18.8 14.2 0.0017 18.0 0.6 4.3 3 1 1 4 4 4 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAG08199.1 - 0.0071 16.3 3.1 0.056 13.3 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 AAG08199.1 - 0.012 14.0 0.0 0.022 13.2 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.24 AAG08199.1 - 0.017 14.4 0.7 0.033 13.5 0.2 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.23 AAG08199.1 - 0.025 14.5 1.8 0.37 10.8 0.0 2.9 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 AAG08199.1 - 0.03 13.6 5.8 0.032 13.5 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain Dus PF01207.17 AAG08199.1 - 0.038 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) AlaDh_PNT_C PF01262.21 AAG08199.1 - 0.054 12.8 0.1 0.054 12.8 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 AAG08199.1 - 0.24 10.5 0.0 13 4.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 AAG08199.1 - 0.31 10.4 0.9 19 4.6 0.4 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAG08199.1 - 0.37 10.4 0.9 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 AAG08199.1 - 1.1 9.2 6.1 1.2 9.1 0.1 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAG08199.1 - 5.5 5.9 6.1 0.28 10.2 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DMT_YdcZ PF04657.13 AAG08200.1 - 1e-40 139.3 19.4 1.2e-40 139.0 19.4 1.0 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ DUF3093 PF11292.8 AAG08200.1 - 1.5 9.1 7.2 3.3 8.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) DUF1835 PF08874.10 AAG08201.1 - 1e-14 54.8 0.0 1.8e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1835) CxxCxxCC PF03692.15 AAG08202.1 - 3.9e-16 59.5 3.6 5.5e-16 59.0 3.6 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain PMT PF02366.18 AAG08203.1 - 5.3e-18 65.5 12.7 5.3e-18 65.5 12.7 2.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 AAG08203.1 - 6e-14 52.6 10.5 6e-14 52.6 10.5 2.7 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glycos_transf_2 PF00535.26 AAG08204.1 - 1e-27 97.1 0.0 1.3e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAG08204.1 - 7.2e-10 39.1 0.0 9.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAG08204.1 - 0.011 16.3 0.0 0.022 15.3 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AAG08204.1 - 0.057 12.9 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Phage_holin_3_6 PF07332.11 AAG08204.1 - 0.072 13.1 1.9 0.15 12.1 1.9 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CAP59_mtransfer PF11735.8 AAG08204.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Glyco_transf_21 PF13506.6 AAG08204.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 GtrA PF04138.14 AAG08205.1 - 3.2e-23 82.2 4.7 3.6e-23 82.0 4.7 1.0 1 0 0 1 1 1 1 GtrA-like protein Polysacc_synt_C PF14667.6 AAG08205.1 - 0.0058 16.7 5.8 0.0073 16.4 5.8 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 AAG08206.1 - 5.1e-34 117.2 24.7 4.1e-20 72.0 8.9 2.2 2 0 0 2 2 2 2 MatE Na_Pi_cotrans PF02690.15 AAG08207.1 - 3.4e-43 147.1 22.1 5e-33 114.1 10.3 2.4 1 1 1 2 2 2 2 Na+/Pi-cotransporter PhoU PF01895.19 AAG08207.1 - 1.9e-12 47.5 7.4 5.9e-07 29.9 1.1 2.2 2 0 0 2 2 2 2 PhoU domain DUF543 PF04418.12 AAG08209.1 - 0.085 12.9 0.4 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) E1-E2_ATPase PF00122.20 AAG08210.1 - 4e-43 147.0 1.0 4e-43 147.0 1.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AAG08210.1 - 2.7e-20 73.6 0.4 6.7e-20 72.3 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 AAG08210.1 - 4.4e-16 59.1 8.9 4.4e-16 59.1 8.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 AAG08210.1 - 1.7e-14 53.2 0.0 3.8e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AAG08210.1 - 1.1e-05 25.4 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AAG08210.1 - 0.0011 18.7 0.0 0.0061 16.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG08210.1 - 0.027 14.9 0.2 0.08 13.3 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acetyltransf_2 PF00797.17 AAG08212.1 - 8.5e-72 241.8 0.0 1e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase Peptidase_C71 PF12386.8 AAG08212.1 - 0.23 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei DUF2214 PF09980.9 AAG08213.1 - 1.5e-53 180.5 9.0 1.7e-53 180.4 9.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2214) Pyr_redox_2 PF07992.14 AAG08214.1 - 2.7e-68 230.4 1.0 4e-68 229.8 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAG08214.1 - 8.5e-40 135.4 0.0 3.4e-39 133.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAG08214.1 - 4.6e-21 75.2 2.2 1e-17 64.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG08214.1 - 8.9e-09 34.5 2.8 0.00042 19.1 0.8 4.1 4 0 0 4 4 4 1 HI0933-like protein FAD_oxidored PF12831.7 AAG08214.1 - 1.9e-08 34.1 0.4 3.2e-08 33.3 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAG08214.1 - 2.2e-07 30.4 1.1 0.0062 15.8 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAG08214.1 - 3.8e-07 29.5 7.3 2.6e-06 26.8 3.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAG08214.1 - 5e-07 29.8 5.8 0.0026 17.9 0.9 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AAG08214.1 - 5.5e-07 29.1 1.2 0.0063 15.8 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AAG08214.1 - 2.1e-06 27.2 11.1 0.014 14.7 0.1 3.3 2 1 1 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.24 AAG08214.1 - 8.2e-06 25.1 9.0 8.9e-06 25.0 2.9 2.7 2 1 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 AAG08214.1 - 1e-05 24.9 0.4 0.068 12.3 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AAG08214.1 - 7.5e-05 22.1 1.9 0.00043 19.6 0.3 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 AAG08214.1 - 0.018 14.1 5.1 0.023 13.8 1.0 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein XdhC_C PF13478.6 AAG08214.1 - 0.026 15.0 0.1 5.1 7.6 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 AAG08214.1 - 0.28 11.1 3.5 0.52 10.2 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AAG08214.1 - 0.43 10.1 20.1 1.6 8.2 0.1 4.3 4 1 0 5 5 5 0 FAD dependent oxidoreductase 4HBT PF03061.22 AAG08215.1 - 7.3e-17 61.5 0.4 1.2e-16 60.9 0.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AAG08215.1 - 0.00033 20.8 0.0 0.00044 20.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AAG08215.1 - 0.023 15.0 0.2 0.035 14.4 0.2 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily TetR_N PF00440.23 AAG08216.1 - 3.7e-12 45.9 0.0 1.2e-11 44.2 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_16 PF17920.1 AAG08216.1 - 0.0039 17.4 0.4 0.0039 17.4 0.4 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 AAG08217.1 - 2.2e-42 144.7 0.1 2.8e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG08217.1 - 5.4e-28 98.1 1.3 6.8e-28 97.8 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG08217.1 - 3.3e-13 49.9 1.7 4.7e-13 49.4 1.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG08217.1 - 7.3e-05 22.3 1.4 0.00016 21.3 1.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 AAG08217.1 - 0.0021 17.7 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 AAG08217.1 - 0.013 15.4 1.1 0.018 14.9 0.9 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AAG08217.1 - 0.029 14.6 0.1 0.044 14.1 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 AAG08217.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HlyIII PF03006.20 AAG08218.1 - 4.8e-45 154.0 17.5 5.4e-45 153.8 17.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF3522 PF12036.8 AAG08218.1 - 0.0094 16.3 6.3 0.0094 16.3 6.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) DUF962 PF06127.11 AAG08218.1 - 1.9 8.6 7.4 0.45 10.6 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF962) EamA PF00892.20 AAG08219.1 - 3e-30 105.2 39.5 9.8e-17 61.4 16.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AAG08219.1 - 0.00013 21.4 11.2 0.00013 21.4 11.2 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family Staph_opine_DH PF10100.9 AAG08220.1 - 1.2e-174 581.0 0.0 1.3e-174 580.8 0.0 1.0 1 0 0 1 1 1 1 Staphylopine dehydrogenase NAS PF03059.16 AAG08221.1 - 7.9e-12 45.1 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 AAG08221.1 - 1.8e-05 24.6 0.0 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08221.1 - 0.00099 19.8 0.1 0.0019 18.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08221.1 - 0.015 15.9 0.1 0.026 15.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain BTK PF00779.19 AAG08221.1 - 0.035 13.9 0.1 0.08 12.8 0.1 1.5 1 0 0 1 1 1 0 BTK motif AlaDh_PNT_C PF01262.21 AAG08221.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_12 PF08242.12 AAG08221.1 - 0.14 12.9 0.0 0.45 11.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AAG08221.1 - 0.18 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TonB_dep_Rec PF00593.24 AAG08222.1 - 1.8e-72 245.8 9.7 1.8e-72 245.8 9.7 1.4 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG08222.1 - 1.6e-16 60.8 0.2 3.5e-16 59.7 0.2 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF2860 PF11059.8 AAG08222.1 - 0.094 11.9 0.1 6.8 5.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2860) DUF1624 PF07786.12 AAG08223.1 - 5.1e-16 58.9 8.8 5.1e-16 58.9 8.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1624) TraX PF05857.11 AAG08223.1 - 0.013 15.6 6.8 0.031 14.3 0.5 2.6 2 1 0 2 2 2 0 TraX protein OpgC_C PF10129.9 AAG08223.1 - 0.63 8.9 27.4 0.0076 15.2 10.4 3.3 1 1 1 2 2 2 0 OpgC protein Orn_Arg_deC_N PF02784.16 AAG08224.1 - 1.1e-43 149.4 0.1 1.6e-43 148.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 AAG08224.1 - 6.6e-23 80.8 1.1 1.4e-22 79.7 0.5 1.9 2 0 0 2 2 2 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 AAG08224.1 - 9.2e-13 48.5 1.1 9.2e-13 48.5 1.1 2.3 2 0 0 2 2 2 1 Arginine decarboxylase C-terminal helical extension Molybdopterin_N PF18364.1 AAG08224.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase N-terminal domain SUI1 PF01253.22 AAG08225.1 - 2.2e-16 60.2 0.2 3.3e-16 59.6 0.1 1.4 1 1 0 1 1 1 1 Translation initiation factor SUI1 A2L_zn_ribbon PF08792.10 AAG08225.1 - 0.067 12.9 0.0 0.067 12.9 0.0 1.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-NADH-PPase PF09297.11 AAG08225.1 - 7.7 6.3 10.0 7.7 6.3 0.8 3.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain NUDIX PF00293.28 AAG08226.1 - 2.3e-16 60.1 0.0 3.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF2333 PF10095.9 AAG08227.1 - 5.4e-163 541.7 0.1 6.9e-163 541.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2333) Zn_peptidase PF04228.13 AAG08227.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase GGDEF PF00990.21 AAG08228.1 - 1.3e-41 142.0 0.0 3.5e-41 140.6 0.0 1.8 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAG08228.1 - 3.4e-27 94.8 0.1 1.4e-21 76.8 0.2 2.4 2 0 0 2 2 2 2 Response regulator receiver domain FleQ PF06490.11 AAG08228.1 - 0.00031 21.1 0.0 0.0078 16.6 0.0 2.5 2 1 0 2 2 2 1 Flagellar regulatory protein FleQ Phage_ABA_S PF18066.1 AAG08228.1 - 0.17 12.6 0.0 0.76 10.5 0.0 2.0 2 0 0 2 2 2 0 Phage ABA sandwich domain MCPsignal PF00015.21 AAG08229.1 - 5.2e-42 143.6 27.0 3.7e-41 140.8 17.5 2.6 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 AAG08229.1 - 8.7e-05 22.8 0.9 0.37 11.1 0.1 4.3 4 1 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 AAG08229.1 - 0.056 13.5 7.2 1.2 9.2 0.0 4.2 5 1 0 5 5 5 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 AAG08229.1 - 0.11 12.6 2.0 28 4.8 0.1 3.6 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 AAG08229.1 - 0.13 12.3 9.6 5.1 7.1 0.1 4.5 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Thioredoxin_4 PF13462.6 AAG08229.1 - 0.18 11.9 0.5 0.45 10.7 0.5 1.6 1 0 0 1 1 1 0 Thioredoxin Helo_like_N PF17111.5 AAG08229.1 - 0.18 11.1 1.6 20 4.5 0.1 3.4 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF948 PF06103.11 AAG08229.1 - 0.33 11.2 9.9 6.5 7.1 0.9 4.8 3 1 1 5 5 4 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 AAG08229.1 - 0.34 9.9 3.8 0.42 9.6 0.2 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Folliculin PF11704.8 AAG08229.1 - 0.8 9.6 4.1 2.8 7.8 0.8 2.5 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Prefoldin_3 PF13758.6 AAG08229.1 - 2.4 8.3 4.7 7.9 6.6 0.1 3.4 3 1 0 3 3 3 0 Prefoldin subunit DUF5344 PF17279.2 AAG08229.1 - 3.2 8.4 7.0 8.9 7.0 0.1 4.6 6 0 0 6 6 5 0 Family of unknown function (DUF5344) RmuC PF02646.16 AAG08229.1 - 4.1 6.5 8.2 1.2 8.2 0.4 3.4 3 1 0 3 3 3 0 RmuC family ATG16 PF08614.11 AAG08229.1 - 7.6 6.7 21.4 3.2 7.9 0.9 4.2 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DsbC PF11412.8 AAG08230.1 - 6.9e-35 119.7 0.1 9.9e-35 119.2 0.1 1.2 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredoxin_7 PF13899.6 AAG08230.1 - 2.7e-19 69.1 0.0 5.2e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.15 AAG08230.1 - 1.1e-11 45.0 15.6 1.6e-11 44.5 15.6 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AAG08230.1 - 1.3e-09 38.3 24.5 1.3e-09 38.3 24.5 2.2 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_2 PF13098.6 AAG08230.1 - 1e-06 29.1 0.0 1.9e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 AAG08230.1 - 6.1e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.15 AAG08230.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DHquinase_II PF01220.19 AAG08231.1 - 1.6e-60 202.8 0.0 1.8e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Biotin_lipoyl PF00364.22 AAG08232.1 - 2.9e-26 91.1 0.1 4.7e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAG08232.1 - 5.5e-10 38.9 0.1 0.00011 22.0 0.0 2.7 2 1 1 3 3 3 2 Biotin-lipoyl like GCV_H PF01597.19 AAG08232.1 - 0.00047 20.0 0.2 0.00098 19.0 0.1 1.6 2 0 0 2 2 2 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 AAG08232.1 - 0.0011 18.2 0.1 0.028 13.6 0.0 2.5 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 AAG08232.1 - 0.003 17.5 0.1 0.0064 16.4 0.1 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 AAG08232.1 - 0.0062 17.2 0.3 0.034 14.8 0.0 2.2 2 1 1 3 3 3 1 HlyD family secretion protein Peptidase_M23 PF01551.22 AAG08232.1 - 0.018 15.3 0.0 0.053 13.7 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M23 YqfD PF06898.11 AAG08232.1 - 0.021 13.7 1.0 0.52 9.1 0.1 2.3 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD CPSase_L_D2 PF02786.17 AAG08233.1 - 3.4e-87 291.4 0.0 5.6e-87 290.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAG08233.1 - 6.6e-45 152.2 0.5 1.4e-44 151.1 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAG08233.1 - 6.3e-39 132.4 0.0 1.3e-38 131.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AAG08233.1 - 1.7e-07 31.0 0.0 3.9e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AAG08233.1 - 5.7e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AAG08233.1 - 2e-06 27.5 0.0 4.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AAG08233.1 - 9.2e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LAL_C2 PF18603.1 AAG08233.1 - 0.012 15.8 0.0 0.043 14.0 0.0 2.0 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 AP_endonuc_2 PF01261.24 AAG08233.1 - 0.12 11.8 0.1 4.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel EI24 PF07264.11 AAG08234.1 - 3.8e-15 56.6 24.5 5e-15 56.2 24.5 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PrmA PF06325.13 AAG08235.1 - 4.1e-101 338.3 0.0 4.6e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAG08235.1 - 2.3e-10 40.3 0.0 3.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAG08235.1 - 6.8e-09 35.7 0.0 1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08235.1 - 2.5e-08 34.5 0.0 5.8e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG08235.1 - 1.2e-05 25.3 0.0 3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08235.1 - 2.1e-05 25.1 0.0 4.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08235.1 - 5.8e-05 23.8 0.0 0.00012 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAG08235.1 - 0.00035 20.4 0.0 0.00058 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 AAG08235.1 - 0.00067 19.4 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 AAG08235.1 - 0.011 15.4 0.1 0.036 13.7 0.1 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.11 AAG08235.1 - 0.018 13.9 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) N6_N4_Mtase PF01555.18 AAG08235.1 - 0.027 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Methyltransf_18 PF12847.7 AAG08235.1 - 0.04 13.8 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 AAG08235.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_32 PF13679.6 AAG08235.1 - 0.23 11.5 0.0 0.35 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3426 PF11906.8 AAG08236.1 - 3.5e-36 124.6 0.0 6.8e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) zinc_ribbon_5 PF13719.6 AAG08236.1 - 1.2e-10 40.9 0.5 2.4e-10 40.0 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.6 AAG08236.1 - 3.5e-09 36.4 1.3 4.6e-09 36.1 0.6 1.6 2 0 0 2 2 2 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AAG08236.1 - 0.24 10.9 0.4 0.47 10.0 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2H2 PF00096.26 AAG08236.1 - 0.47 11.0 1.9 9.6 6.9 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Dus PF01207.17 AAG08237.1 - 5.5e-110 367.3 0.0 6.3e-110 367.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NanE PF04131.14 AAG08237.1 - 0.00014 21.2 0.4 0.00042 19.6 0.1 1.9 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase SOR_SNZ PF01680.17 AAG08237.1 - 0.00015 21.6 1.6 0.0025 17.6 0.3 2.3 1 1 1 2 2 2 1 SOR/SNZ family His_biosynth PF00977.21 AAG08237.1 - 0.00038 20.0 0.3 0.00057 19.4 0.3 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein PEP_mutase PF13714.6 AAG08237.1 - 0.0037 16.8 1.0 0.0095 15.4 1.0 1.8 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MukE PF04288.13 AAG08237.1 - 0.012 14.6 0.0 0.29 10.0 0.0 2.2 2 0 0 2 2 2 0 MukE-like family MR_MLE_C PF13378.6 AAG08237.1 - 0.021 14.4 1.0 0.13 11.8 1.0 2.2 1 1 0 1 1 1 0 Enolase C-terminal domain-like TMP-TENI PF02581.17 AAG08237.1 - 0.1 11.9 1.0 0.19 11.1 0.1 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 AAG08237.1 - 0.16 11.2 1.3 1.3 8.3 0.1 2.6 3 1 0 3 3 3 0 NADH:flavin oxidoreductase / NADH oxidase family HTH_8 PF02954.19 AAG08238.1 - 5.5e-14 51.7 0.1 8.9e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Phage_NinH PF06322.11 AAG08238.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Phage NinH protein RBD PF02196.15 AAG08238.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain HTH_28 PF13518.6 AAG08238.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 AAG08238.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain AICARFT_IMPCHas PF01808.18 AAG08239.1 - 5.8e-115 383.8 2.8 7e-115 383.5 2.8 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 AAG08239.1 - 7.4e-28 96.6 0.0 2e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain GARS_A PF01071.19 AAG08240.1 - 1.7e-82 275.9 0.0 2.4e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AAG08240.1 - 1.4e-33 115.5 0.2 3e-33 114.5 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AAG08240.1 - 4e-30 103.9 2.3 8.6e-30 102.9 0.9 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 AAG08240.1 - 2.4e-05 24.4 0.0 5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAG08240.1 - 2.5e-05 23.9 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AAG08240.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAG08240.1 - 0.0042 16.7 0.0 0.013 15.1 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AAG08240.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Response_reg PF00072.24 AAG08241.1 - 6.5e-44 148.7 0.3 4.4e-22 78.4 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain 7TMR-DISM_7TM PF07695.11 AAG08241.1 - 8e-23 81.4 26.7 1.4e-22 80.6 26.7 1.3 1 0 0 1 1 1 1 7TM diverse intracellular signalling 7TMR-DISMED2 PF07696.11 AAG08241.1 - 1.4e-21 77.0 1.7 2.6e-21 76.1 1.7 1.5 1 0 0 1 1 1 1 7TMR-DISM extracellular 2 HisKA PF00512.25 AAG08241.1 - 4.8e-19 68.1 0.3 2e-18 66.2 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAG08241.1 - 4.2e-16 59.4 0.0 7.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAG08241.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MarC PF01914.17 AAG08242.1 - 6.7e-37 126.9 9.0 7.7e-37 126.7 9.0 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein DUF1624 PF07786.12 AAG08242.1 - 0.74 9.3 8.5 0.64 9.5 2.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1624) Peripla_BP_5 PF13433.6 AAG08243.1 - 1.4e-174 580.3 0.0 1.5e-174 580.1 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AAG08243.1 - 7.6e-73 246.1 1.1 8.9e-73 245.9 1.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAG08243.1 - 0.0012 18.0 0.0 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 Receptor family ligand binding region Pex14_N PF04695.13 AAG08243.1 - 0.15 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BPD_transp_2 PF02653.16 AAG08244.1 - 4e-55 186.8 35.5 4.7e-55 186.6 35.5 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Peptidase_M48_N PF16491.5 AAG08244.1 - 1.4 8.7 4.8 0.57 10.0 1.5 2.0 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices BPD_transp_2 PF02653.16 AAG08245.1 - 9.3e-42 143.0 28.7 9.3e-42 143.0 28.7 1.5 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component FxsA PF04186.13 AAG08245.1 - 0.011 15.8 10.4 0.37 10.9 0.2 3.1 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein ABC_tran PF00005.27 AAG08246.1 - 2e-27 96.4 0.0 2.9e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAG08246.1 - 8.8e-09 35.1 0.1 1.6e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAG08246.1 - 5e-08 33.1 0.8 0.00034 20.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG08246.1 - 2e-06 27.4 0.0 2e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAG08246.1 - 3.9e-06 27.5 0.6 9.7e-06 26.2 0.1 1.6 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 AAG08246.1 - 0.00028 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG08246.1 - 0.001 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAG08246.1 - 0.0022 18.3 0.9 0.023 15.0 0.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG08246.1 - 0.0073 16.0 0.5 0.051 13.3 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG08246.1 - 0.026 14.9 0.5 0.052 13.9 0.5 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAG08246.1 - 0.033 14.3 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAG08246.1 - 0.062 13.2 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NADPH_Ox PF08414.10 AAG08246.1 - 0.083 13.2 0.1 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase IstB_IS21 PF01695.17 AAG08246.1 - 0.084 12.6 0.1 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 AAG08246.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 AAG08246.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAG08247.1 - 1.4e-31 109.9 0.0 1.8e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG08247.1 - 8.2e-11 42.2 0.0 1.5e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAG08247.1 - 0.0019 18.8 0.0 0.0027 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG08247.1 - 0.0028 18.1 0.2 0.004 17.5 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG08247.1 - 0.0041 17.0 0.1 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AAG08247.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAG08247.1 - 0.0086 15.8 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 AAG08247.1 - 0.018 15.0 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AAG08247.1 - 0.023 14.9 0.3 0.13 12.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAG08247.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3584 PF12128.8 AAG08247.1 - 0.07 10.6 0.2 0.093 10.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_30 PF13604.6 AAG08247.1 - 0.11 12.2 0.4 0.27 10.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAG08247.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Acetyltransf_1 PF00583.25 AAG08248.1 - 6.5e-14 52.2 0.0 8.4e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG08248.1 - 2.6e-13 50.0 0.0 3.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG08248.1 - 7.8e-13 48.7 0.1 1.4e-12 47.8 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAG08248.1 - 5.2e-05 23.3 0.0 0.0016 18.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG08248.1 - 0.00074 19.4 0.0 0.0015 18.5 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 AAG08248.1 - 0.0076 16.4 0.0 0.088 13.0 0.0 2.1 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 AAG08248.1 - 0.029 14.5 0.1 0.049 13.8 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAG08248.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ UreD PF01774.17 AAG08249.1 - 2.8e-49 167.9 0.0 3.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Urease_gamma PF00547.18 AAG08250.1 - 3.7e-47 158.7 0.0 4.1e-47 158.5 0.0 1.0 1 0 0 1 1 1 1 Urease, gamma subunit Acetyltransf_4 PF13420.7 AAG08251.1 - 1.2e-21 77.5 0.0 1.3e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG08251.1 - 4.4e-18 65.6 0.1 5.2e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAG08251.1 - 2.2e-13 51.1 0.0 2.8e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG08251.1 - 2e-09 37.3 0.1 4e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 AAG08251.1 - 7.7e-08 32.7 0.1 1.2e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG08251.1 - 7.9e-08 32.3 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG08251.1 - 7.1e-05 22.9 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 AAG08251.1 - 0.00024 20.8 0.0 0.0003 20.4 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 AAG08251.1 - 0.038 14.1 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2156 PF09924.9 AAG08251.1 - 0.13 11.2 0.1 0.39 9.7 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Urease_beta PF00699.20 AAG08252.1 - 7.6e-46 154.1 0.0 8.4e-46 154.0 0.0 1.0 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_1 PF01979.20 AAG08253.1 - 3e-79 266.9 0.9 3.9e-79 266.5 0.9 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 AAG08253.1 - 1.2e-56 190.3 2.6 2.2e-56 189.4 2.6 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 AAG08253.1 - 9e-10 38.6 1.6 8.7e-06 25.5 0.2 2.7 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 AAG08253.1 - 0.08 12.7 0.1 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 Amidohydrolase Molybdopterin_N PF18364.1 AAG08253.1 - 0.11 12.6 0.1 0.36 10.9 0.1 1.9 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain FG-GAP PF01839.23 AAG08254.1 - 0.021 15.0 1.8 0.021 14.9 0.3 1.7 2 0 0 2 2 2 0 FG-GAP repeat VCBS PF13517.6 AAG08254.1 - 0.036 14.7 0.1 0.17 12.5 0.0 2.2 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF5597 PF18120.1 AAG08254.1 - 0.089 12.9 0.1 0.21 11.7 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5597) zf-dskA_traR PF01258.17 AAG08255.1 - 8.3e-14 51.2 3.7 1.3e-13 50.6 3.7 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 AAG08255.1 - 0.0034 17.4 0.5 0.0043 17.0 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon Auto_anti-p27 PF06677.12 AAG08255.1 - 0.026 14.7 1.3 0.044 13.9 1.3 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PEP_mutase PF13714.6 AAG08257.1 - 1.1e-43 149.5 3.2 1.3e-43 149.2 3.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AAG08257.1 - 0.015 13.8 0.5 0.026 13.0 0.5 1.4 1 0 0 1 1 1 0 Isocitrate lyase family HSP70 PF00012.20 AAG08258.1 - 2.5e-27 95.3 0.0 6.8e-10 37.8 0.0 3.0 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 AAG08258.1 - 1.7e-05 23.9 0.0 7.1e-05 21.8 0.0 2.0 3 0 0 3 3 3 1 MreB/Mbl protein StbA PF06406.11 AAG08258.1 - 0.0038 16.5 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 StbA protein Hydantoinase_A PF01968.18 AAG08258.1 - 0.025 13.8 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PilM_2 PF11104.8 AAG08258.1 - 0.035 13.1 0.0 0.09 11.8 0.0 1.6 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; PsiF_repeat PF07769.14 AAG08259.1 - 1.1e-59 197.9 35.2 7.8e-20 70.5 6.6 3.1 3 0 0 3 3 3 3 psiF repeat DUF4150 PF13665.6 AAG08259.1 - 0.15 12.3 1.3 2.9 8.1 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4150) DUF2957 PF11170.8 AAG08259.1 - 0.6 8.9 10.5 2.5 6.9 1.5 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2957) Ole-e-6 PF09253.10 AAG08259.1 - 7.8 6.5 9.6 26 4.9 0.7 3.4 3 0 0 3 3 3 0 Pollen allergen ole e 6 DUF1771 PF08590.10 AAG08259.1 - 9.1 6.7 18.1 25 5.3 9.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1771) MOSC PF03473.17 AAG08260.1 - 0.00091 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain SmpA_OmlA PF04355.13 AAG08261.1 - 3.4e-14 52.4 0.0 4.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 SmpA / OmlA family Rho_N PF07498.12 AAG08262.1 - 5.9e-08 32.5 0.9 1.1e-07 31.6 0.9 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Cass2 PF14526.6 AAG08263.1 - 9.4e-38 129.7 0.0 1.5e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Integron-associated effector binding protein GyrI-like PF06445.15 AAG08263.1 - 8.4e-28 97.6 0.2 1.1e-27 97.2 0.2 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain MerR_1 PF13411.6 AAG08263.1 - 4e-16 58.9 0.1 9.8e-16 57.6 0.1 1.7 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAG08263.1 - 2.4e-12 46.4 0.3 6.2e-12 45.1 0.3 1.8 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 AAG08263.1 - 0.02 15.4 10.3 0.032 14.8 10.3 1.3 1 0 0 1 1 1 0 MerR, DNA binding AsmA PF05170.14 AAG08264.1 - 2.2e-182 608.1 0.0 2.5e-182 607.9 0.0 1.0 1 0 0 1 1 1 1 AsmA family AsmA_2 PF13502.6 AAG08264.1 - 5.6e-19 68.6 3.2 1.8e-18 66.9 2.1 2.3 2 0 0 2 2 2 1 AsmA-like C-terminal region DUF748 PF05359.11 AAG08264.1 - 0.0073 16.5 1.8 3.7 7.7 0.1 4.6 3 1 2 5 5 5 1 Domain of Unknown Function (DUF748) Ferritin PF00210.24 AAG08265.1 - 3e-28 98.5 2.9 3.6e-28 98.3 2.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AAG08265.1 - 5e-08 33.4 2.3 8.4e-08 32.7 2.3 1.4 1 0 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 AAG08265.1 - 0.0036 17.6 1.0 0.054 13.8 0.3 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF2383) Ferritin_2 PF13668.6 AAG08265.1 - 0.0039 17.4 2.0 0.3 11.3 2.1 2.2 1 1 0 1 1 1 1 Ferritin-like domain COQ7 PF03232.13 AAG08265.1 - 0.0067 16.2 0.2 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 DUF892 PF05974.12 AAG08265.1 - 0.02 14.9 4.5 0.048 13.7 3.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF892) APG17 PF04108.12 AAG08265.1 - 0.025 13.7 0.2 0.24 10.5 0.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 Ald_deCOase PF11266.8 AAG08265.1 - 0.037 13.7 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase Proteasome PF00227.26 AAG08265.1 - 0.11 11.9 0.4 0.77 9.2 0.2 2.0 1 1 1 2 2 2 0 Proteasome subunit Coat_F PF07875.12 AAG08265.1 - 1.2 9.4 3.8 4.5 7.6 0.1 2.8 3 1 0 3 3 3 0 Coat F domain ABC_tran_CTD PF16326.5 AAG08266.1 - 0.00079 19.6 0.5 0.012 15.8 0.6 2.3 1 1 2 3 3 3 3 ABC transporter C-terminal domain DUF1476 PF07345.11 AAG08266.1 - 0.042 14.2 2.9 4.5 7.7 0.5 2.7 1 1 2 3 3 3 0 ATPase inhibitor subunit zeta PLN_propep PF16485.5 AAG08266.1 - 0.053 13.2 0.3 13 5.6 0.0 3.1 3 0 0 3 3 3 0 Protealysin propeptide ICEA PF05315.11 AAG08266.1 - 0.054 12.9 0.2 0.08 12.4 0.2 1.3 1 1 0 1 1 1 0 ICEA Protein HP0268 PF18618.1 AAG08266.1 - 0.055 13.9 0.3 10 6.6 0.0 2.7 1 1 1 2 2 2 0 HP0268 LTXXQ PF07813.12 AAG08266.1 - 0.08 13.7 2.8 8.3 7.2 0.2 2.3 1 1 2 3 3 3 0 LTXXQ motif family protein TMF_DNA_bd PF12329.8 AAG08266.1 - 0.094 12.7 1.0 0.95 9.5 0.7 2.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 AAG08266.1 - 0.5 10.6 4.1 21 5.4 0.2 3.1 1 1 3 4 4 4 0 Haemolysin XhlA Oxidored_molyb PF00174.19 AAG08267.1 - 9.9e-36 122.9 0.0 1.3e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain TAT_signal PF10518.9 AAG08267.1 - 0.02 14.7 1.3 0.042 13.7 1.3 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Ni_hydr_CYTB PF01292.20 AAG08268.1 - 6.1e-23 81.3 20.3 7.2e-23 81.1 20.3 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DuoxA PF10204.9 AAG08268.1 - 0.24 10.4 3.8 0.69 8.9 1.7 2.1 2 0 0 2 2 2 0 Dual oxidase maturation factor Trans_reg_C PF00486.28 AAG08270.1 - 3.8e-26 91.0 0.0 8.7e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAG08270.1 - 2.5e-25 88.8 0.0 5.6e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 AAG08271.1 - 1e-12 48.6 0.0 1.8e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG08271.1 - 3e-12 46.4 2.2 6.3e-12 45.3 0.6 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAG08271.1 - 1.1e-10 41.7 0.9 3.2e-10 40.2 0.9 1.9 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 AAG08271.1 - 0.00041 20.2 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 GHKL domain DinB_2 PF12867.7 AAG08271.1 - 0.031 14.8 0.5 0.031 14.8 0.5 2.1 2 0 0 2 2 2 0 DinB superfamily HATPase_c_2 PF13581.6 AAG08271.1 - 0.073 13.0 0.1 0.37 10.7 0.0 2.2 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain DUF4307 PF14155.6 AAG08271.1 - 0.22 11.4 1.0 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) MFS_1 PF07690.16 AAG08272.1 - 1.9e-24 86.3 35.9 1.5e-18 66.9 17.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG08272.1 - 1.9e-10 40.2 25.2 1e-07 31.2 6.0 3.4 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_4 PF06779.14 AAG08272.1 - 0.00025 20.5 21.9 0.00037 19.9 21.9 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 AAG08272.1 - 0.00037 19.0 1.7 0.00037 19.0 1.7 2.3 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 AAG08272.1 - 0.00064 18.7 21.1 0.022 13.6 5.8 2.3 1 1 1 2 2 2 2 MFS_1 like family FA_desaturase PF00487.24 AAG08273.1 - 1.2e-30 107.2 16.7 1.2e-30 107.2 16.7 1.4 1 1 0 1 1 1 1 Fatty acid desaturase NAD_binding_1 PF00175.21 AAG08274.1 - 1.3e-09 38.7 0.0 1.9e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAG08274.1 - 5.5e-06 26.7 0.0 8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 AAG08274.1 - 2.9e-05 23.9 2.8 0.00012 21.9 3.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AAG08274.1 - 0.074 13.2 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain TetR_N PF00440.23 AAG08275.1 - 6.2e-09 35.5 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family RE_XcyI PF09571.10 AAG08275.1 - 0.22 10.8 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 XcyI restriction endonuclease UreE_C PF05194.12 AAG08276.1 - 2.2e-28 98.6 1.1 3e-28 98.1 1.1 1.2 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain UreE_N PF02814.15 AAG08276.1 - 3e-21 74.8 0.1 5.6e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain UreF PF01730.16 AAG08277.1 - 2.5e-35 122.0 14.5 4.2e-35 121.2 14.5 1.4 1 0 0 1 1 1 1 UreF cobW PF02492.19 AAG08278.1 - 2.3e-35 121.8 0.0 3e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AAG08278.1 - 2.1e-05 23.6 0.0 0.033 13.2 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB TIP49 PF06068.13 AAG08278.1 - 0.0051 16.1 0.0 0.0074 15.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Zeta_toxin PF06414.12 AAG08278.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 AAG08278.1 - 0.013 16.0 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AAG08278.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MMR_HSR1 PF01926.23 AAG08278.1 - 0.014 15.5 0.0 0.037 14.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 AAG08278.1 - 0.026 14.9 0.0 0.026 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 AAG08278.1 - 0.046 13.7 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 AAG08278.1 - 0.081 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 AAG08278.1 - 0.094 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.23 AAG08278.1 - 0.095 12.8 0.0 0.11 12.6 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 AAG08278.1 - 0.16 12.5 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter HupE_UreJ PF04955.12 AAG08279.1 - 2.5e-61 206.3 29.8 3e-61 206.0 29.8 1.0 1 0 0 1 1 1 1 HupE / UreJ protein HupE_UreJ_2 PF13795.6 AAG08279.1 - 0.00022 20.9 2.0 0.00034 20.3 2.0 1.3 1 0 0 1 1 1 1 HupE / UreJ protein FecR PF04773.13 AAG08280.1 - 2.7e-21 76.0 0.0 4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAG08280.1 - 4.1e-12 45.8 8.9 4.1e-12 45.8 8.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AAG08280.1 - 0.0049 16.8 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) DDE_Tnp_ISL3 PF01610.17 AAG08280.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Transposase ORF_2_N PF18492.1 AAG08280.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Open reading frame 2 N-terminal domain Sigma70_r4_2 PF08281.12 AAG08281.1 - 3.7e-14 52.1 0.4 4.8e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAG08281.1 - 2.6e-06 27.1 3.3 5.2e-06 26.1 3.3 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAG08281.1 - 5e-05 22.7 0.0 0.00023 20.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAG08281.1 - 0.00011 21.9 0.2 0.00032 20.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 AAG08281.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 AAG08281.1 - 0.072 13.0 0.1 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 ECF sigma factor Annexin PF00191.20 AAG08281.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Annexin GerE PF00196.19 AAG08281.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_IclR PF09339.10 AAG08281.1 - 0.13 12.1 0.4 0.69 9.8 0.1 2.4 2 1 0 2 2 2 0 IclR helix-turn-helix domain TonB_dep_Rec PF00593.24 AAG08282.1 - 5.8e-41 141.8 44.9 2.7e-40 139.6 31.8 3.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAG08282.1 - 1.5e-17 64.1 3.5 3.8e-17 62.8 3.5 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAG08282.1 - 5e-07 29.4 0.0 1.5e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain OprD PF03573.13 AAG08283.1 - 1.2e-148 495.4 3.0 1.4e-148 495.2 3.0 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Nitroreductase PF00881.24 AAG08283.1 - 0.042 13.9 0.0 0.088 12.9 0.0 1.5 2 0 0 2 2 2 0 Nitroreductase family Aldedh PF00171.22 AAG08284.1 - 6.9e-152 506.2 0.0 7.8e-152 506.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 AAG08285.1 - 7.6e-43 146.8 56.4 5.5e-30 104.5 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG08285.1 - 5e-25 88.3 19.7 1.6e-24 86.7 4.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAG08285.1 - 6e-07 29.1 35.6 1e-06 28.3 9.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 AAG08285.1 - 1.1e-05 24.1 0.4 2e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 AAG08285.1 - 4.3e-05 22.6 0.2 4.3e-05 22.6 0.2 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 AAG08285.1 - 0.00024 20.1 18.8 0.0096 14.8 0.0 3.1 2 1 1 3 3 3 2 MFS_1 like family MFS_3 PF05977.13 AAG08285.1 - 0.0019 16.7 15.7 0.0019 16.7 15.7 2.4 2 0 0 2 2 2 1 Transmembrane secretion effector TPP_enzyme_N PF02776.18 AAG08286.1 - 1.4e-46 158.2 0.4 4e-42 143.8 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAG08286.1 - 3.1e-29 101.7 0.0 6.7e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG08286.1 - 3.1e-19 69.1 0.0 6.6e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.10 AAG08286.1 - 0.00051 19.0 0.0 0.0008 18.3 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain E1_dh PF00676.20 AAG08286.1 - 0.16 10.9 0.1 0.34 9.8 0.1 1.5 1 1 0 1 1 1 0 Dehydrogenase E1 component LysR_substrate PF03466.20 AAG08287.1 - 1.4e-24 86.6 5.3 2.3e-24 85.9 5.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08287.1 - 5.7e-18 64.6 1.6 6.9e-18 64.4 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG08287.1 - 0.00074 19.3 0.6 0.0018 18.1 0.2 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG08287.1 - 0.077 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 MarR family MFS_1 PF07690.16 AAG08288.1 - 8.7e-42 143.3 80.6 3e-36 125.1 47.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG08288.1 - 4e-19 68.8 24.2 7.4e-19 67.9 24.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 AAG08288.1 - 4.9 6.3 45.7 0.043 13.1 18.1 2.2 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB Rieske PF00355.26 AAG08289.1 - 1.1e-17 63.8 0.0 1.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 AAG08289.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Pheophorbide a oxygenase Fer2 PF00111.27 AAG08290.1 - 3.3e-13 49.4 2.5 5.8e-13 48.6 2.5 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAG08290.1 - 7.7e-06 25.9 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AAG08290.1 - 0.00027 21.5 0.0 0.013 16.2 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 AAG08290.1 - 0.24 11.5 0.1 2.4 8.3 0.1 2.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain FCD PF07729.12 AAG08291.1 - 1.1e-17 64.7 11.5 1.1e-17 64.7 11.5 1.6 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 AAG08291.1 - 2.6e-12 46.2 0.9 6.7e-12 44.9 0.9 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family DUF1611 PF07755.11 AAG08291.1 - 0.036 13.3 0.1 0.23 10.7 0.0 2.2 2 1 2 4 4 4 0 Domain of unknown function (DUF1611_C) P-loop domain ABATE PF07336.11 AAG08291.1 - 2.1 9.0 11.9 0.045 14.4 3.4 2.1 2 1 0 2 2 2 0 Putative stress-induced transcription regulator adh_short PF00106.25 AAG08292.1 - 2.6e-47 160.8 0.0 3.3e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG08292.1 - 1.6e-35 122.8 0.0 1.9e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG08292.1 - 2.4e-15 56.9 0.0 3.1e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AAG08292.1 - 0.0012 18.0 0.0 0.022 13.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AAG08292.1 - 0.2 11.1 0.0 1.2 8.5 0.0 2.1 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family OCD_Mu_crystall PF02423.15 AAG08293.1 - 3e-62 210.4 0.1 3.4e-62 210.2 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 AAG08293.1 - 6.9e-08 32.6 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ABC_tran PF00005.27 AAG08294.1 - 3.2e-32 111.9 0.0 4.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG08294.1 - 9.7e-11 42.0 2.7 4.3e-06 26.8 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG08294.1 - 4.7e-05 22.9 0.1 0.0071 15.8 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAG08294.1 - 0.00021 21.1 0.0 0.0071 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAG08294.1 - 0.00044 19.9 0.2 0.0013 18.4 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAG08294.1 - 0.00081 19.8 0.1 0.0014 19.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AAG08294.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAG08294.1 - 0.003 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAG08294.1 - 0.022 15.0 0.2 0.17 12.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain BCA_ABC_TP_C PF12399.8 AAG08294.1 - 0.037 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Dynamin_N PF00350.23 AAG08294.1 - 0.042 13.9 0.1 0.47 10.5 0.1 2.0 1 1 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 AAG08294.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAG08294.1 - 0.045 14.3 0.1 0.076 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAG08294.1 - 0.078 13.1 0.0 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAG08294.1 - 0.1 11.7 0.3 0.45 9.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 AAG08294.1 - 0.12 12.4 0.0 2.4 8.2 0.0 2.5 2 2 1 3 3 3 0 AAA domain NACHT PF05729.12 AAG08294.1 - 0.16 11.9 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 AAG08295.1 - 2e-27 96.4 0.0 7.5e-27 94.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG08295.1 - 3.5e-10 40.2 0.1 0.00011 22.2 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AAG08295.1 - 8.7e-09 35.1 0.2 1.4e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AAG08295.1 - 3.9e-06 27.5 0.9 5.8e-06 26.9 0.9 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAG08295.1 - 0.00013 21.4 0.1 0.034 13.6 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG08295.1 - 0.00079 19.7 0.1 0.027 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AAG08295.1 - 0.0008 19.0 0.3 0.39 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 AAG08295.1 - 0.0012 18.6 0.1 0.0029 17.4 0.1 1.6 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 AAG08295.1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 AAG08295.1 - 0.0017 18.0 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAG08295.1 - 0.0028 17.4 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AAG08295.1 - 0.0052 15.6 0.2 0.18 10.5 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AAG08295.1 - 0.0073 16.2 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 AAG08295.1 - 0.015 14.8 0.1 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B SRP54 PF00448.22 AAG08295.1 - 0.029 14.0 0.6 0.054 13.1 0.6 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AAG08295.1 - 0.033 14.6 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 AAG08295.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain BPD_transp_2 PF02653.16 AAG08296.1 - 1.7e-46 158.6 35.9 1.7e-46 158.6 35.9 2.1 1 1 1 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3382 PF11862.8 AAG08296.1 - 1.2e-19 70.3 1.6 1.2e-19 70.3 1.6 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF3382) DUF443 PF04276.12 AAG08296.1 - 4 7.2 9.9 0.52 10.1 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF443) BPD_transp_2 PF02653.16 AAG08297.1 - 2.3e-50 171.3 35.4 2.6e-50 171.1 35.4 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component UPF0093 PF03653.13 AAG08297.1 - 0.026 14.7 0.7 0.026 14.7 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) E1-E2_ATPase PF00122.20 AAG08297.1 - 2.9 7.4 8.4 0.083 12.4 0.3 2.3 2 2 1 3 3 3 0 E1-E2 ATPase Dpy19 PF10034.9 AAG08297.1 - 5.4 5.1 9.1 0.74 7.9 1.9 2.1 1 1 0 2 2 2 0 Q-cell neuroblast polarisation Peripla_BP_6 PF13458.6 AAG08298.1 - 1.1e-64 219.3 8.3 1.2e-64 219.1 8.3 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAG08298.1 - 2.9e-25 89.2 0.0 4.3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAG08298.1 - 3.7e-18 65.6 0.1 8.9e-18 64.4 0.1 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain Toprim_2 PF13155.6 AAG08298.1 - 0.025 15.0 0.1 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 Toprim-like LysR_substrate PF03466.20 AAG08299.1 - 2e-40 138.4 1.9 3.1e-40 137.8 1.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08299.1 - 1.1e-21 76.6 3.6 2e-21 75.7 3.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAG08299.1 - 0.05 13.7 0.5 0.14 12.3 0.5 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MCPsignal PF00015.21 AAG08300.1 - 1e-41 142.6 40.4 5.1e-41 140.3 26.1 3.1 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAG08300.1 - 3.6e-09 36.4 0.0 3.6e-09 36.4 0.0 4.1 4 0 0 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAG08300.1 - 3.7e-08 33.6 1.0 3.7e-08 33.6 1.0 5.3 6 1 0 6 6 6 1 HAMP domain Dioxygenase_N PF04444.14 AAG08300.1 - 0.047 13.5 0.4 0.23 11.3 0.1 2.4 2 0 0 2 2 2 0 Catechol dioxygenase N terminus SKA2 PF16740.5 AAG08300.1 - 0.09 12.6 10.6 1.5 8.6 2.8 3.7 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Snapin_Pallidin PF14712.6 AAG08300.1 - 0.13 12.6 5.2 5.2 7.6 0.1 4.1 4 0 0 4 4 4 0 Snapin/Pallidin PHA_synth_III_E PF09712.10 AAG08300.1 - 1.9 7.5 9.3 1.1 8.3 0.8 2.3 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF948 PF06103.11 AAG08300.1 - 4.6 7.6 29.0 5.3 7.4 4.8 6.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Folliculin PF11704.8 AAG08300.1 - 9.5 6.1 12.3 0.34 10.8 2.1 2.7 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport NUDIX PF00293.28 AAG08301.1 - 6e-05 23.1 0.0 8.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF1731 PF08338.11 AAG08301.1 - 0.063 13.1 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) CTP_transf_like PF01467.26 AAG08302.1 - 3.5e-06 27.3 0.0 5.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 AAG08302.1 - 0.00047 19.7 0.0 0.099 12.1 0.0 2.1 2 0 0 2 2 2 2 ATP-sulfurylase FAD_syn PF06574.12 AAG08302.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD synthetase Isochorismatase PF00857.20 AAG08303.1 - 3.8e-21 76.1 0.0 5.2e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MarB PF13999.6 AAG08303.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 MarB protein NAPRTase PF04095.16 AAG08304.1 - 1.5e-88 296.5 0.0 1.8e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 AAG08304.1 - 2.4e-34 118.4 0.1 5.6e-34 117.2 0.1 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain XkdW PF09636.10 AAG08304.1 - 0.13 12.3 0.0 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 XkdW protein NAD_synthase PF02540.17 AAG08305.1 - 7.2e-65 218.5 0.0 9e-65 218.2 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Lipase_GDSL PF00657.22 AAG08306.1 - 3.9e-06 27.0 0.1 1.6e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Copper-bind PF00127.20 AAG08307.1 - 2.4e-32 111.3 0.2 2.8e-32 111.1 0.2 1.0 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Lysine_decarbox PF03641.14 AAG08308.1 - 4.7e-42 143.2 0.0 5.7e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AAG08308.1 - 5.7e-17 61.7 0.3 7e-17 61.5 0.3 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 AAG08308.1 - 0.027 13.7 0.3 0.037 13.3 0.3 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A Peptidase_M23 PF01551.22 AAG08309.1 - 1.5e-27 95.6 1.2 2.5e-27 94.9 0.2 1.8 2 1 0 2 2 2 1 Peptidase family M23 LysM PF01476.20 AAG08309.1 - 1.4e-14 53.9 0.0 3.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 LysM domain Biotin_lipoyl_2 PF13533.6 AAG08309.1 - 2e-05 24.3 3.0 0.016 15.0 0.0 3.6 4 0 0 4 4 4 2 Biotin-lipoyl like RnfC_N PF13375.6 AAG08309.1 - 0.0007 19.5 0.3 0.11 12.5 0.0 2.6 3 0 0 3 3 3 2 RnfC Barrel sandwich hybrid domain MS_channel PF00924.18 AAG08310.1 - 1.2e-36 126.2 0.2 1.8e-36 125.6 0.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel TM_helix PF05552.12 AAG08310.1 - 0.00017 21.5 0.6 0.00017 21.5 0.6 3.3 4 0 0 4 4 4 1 Conserved TM helix Tetraspanin PF00335.20 AAG08310.1 - 0.26 11.0 8.0 0.34 10.6 8.0 1.2 1 0 0 1 1 1 0 Tetraspanin family Bact_transglu_N PF08379.10 AAG08311.1 - 1.3e-24 86.9 0.1 6.3e-24 84.7 0.2 2.0 2 0 0 2 2 2 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AAG08311.1 - 1.4e-22 80.3 0.0 2.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AAG08311.1 - 0.00023 20.7 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like domain Transglut_core2 PF13369.6 AAG08311.1 - 0.069 12.7 0.1 0.17 11.4 0.1 1.6 1 1 0 1 1 1 0 Transglutaminase-like superfamily CP_ATPgrasp_2 PF14403.6 AAG08312.1 - 5.4e-156 519.2 0.0 7.2e-156 518.8 0.0 1.2 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AAG08312.1 - 9.4e-118 393.0 0.0 1.2e-117 392.6 0.0 1.2 1 0 0 1 1 1 1 A circularly permuted ATPgrasp Alpha-E PF04168.12 AAG08312.1 - 2.9e-72 243.9 5.0 5.4e-72 243.0 5.0 1.5 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. Radical_SAM_N PF08497.10 AAG08313.1 - 1.9e-146 487.0 0.0 2.5e-146 486.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM N-terminal DUF3362 PF11842.8 AAG08313.1 - 4.8e-53 179.5 1.1 9.5e-53 178.6 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3362) Radical_SAM PF04055.21 AAG08313.1 - 1e-22 81.3 0.2 4.8e-22 79.1 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAG08313.1 - 0.0037 17.3 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 1 B12 binding domain GGDEF PF00990.21 AAG08314.1 - 4.8e-49 166.2 0.0 8.3e-49 165.4 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain 7TMR-DISM_7TM PF07695.11 AAG08314.1 - 1.8e-37 129.3 22.6 1.8e-37 129.3 22.6 1.7 2 0 0 2 2 2 1 7TM diverse intracellular signalling 7TMR-DISMED2 PF07696.11 AAG08314.1 - 4.3e-26 91.5 0.0 9.4e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 7TMR-DISM extracellular 2 TEX13 PF15186.6 AAG08314.1 - 0.34 10.6 5.1 0.66 9.7 5.1 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Ala_racemase_N PF01168.20 AAG08315.1 - 1.2e-61 208.2 0.8 1.5e-61 207.9 0.8 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 AAG08315.1 - 1.5e-41 141.0 0.0 2.3e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Herpeto_peptide PF14409.6 AAG08315.1 - 0.052 13.8 0.1 0.17 12.1 0.1 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon DnaB_C PF03796.15 AAG08316.1 - 1.1e-113 378.7 0.0 1.8e-113 378.1 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 AAG08316.1 - 5.8e-38 129.1 0.0 1.7e-37 127.6 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 AAG08316.1 - 2e-11 43.8 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AAG08316.1 - 4.2e-08 32.8 0.1 7.8e-06 25.4 0.0 2.5 1 1 1 2 2 2 2 KaiC MMR_HSR1 PF01926.23 AAG08316.1 - 0.00074 19.6 0.1 0.021 14.9 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AAG08316.1 - 0.0025 18.1 0.0 0.0074 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAG08316.1 - 0.01 16.0 0.0 0.034 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 AAG08316.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 AAG08316.1 - 0.079 12.7 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AAG08316.1 - 0.082 12.3 0.0 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family PSY3 PF16836.5 AAG08316.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description Ribosomal_L9_C PF03948.14 AAG08317.1 - 2.2e-23 82.5 0.0 3.8e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 AAG08317.1 - 1.9e-20 72.1 0.6 1.9e-20 72.1 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Cob_adeno_trans PF01923.18 AAG08317.1 - 0.025 14.7 0.1 0.039 14.1 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase LAB_N PF07578.11 AAG08318.1 - 0.014 15.4 3.6 0.083 13.0 0.1 2.7 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain Ribosomal_S18 PF01084.20 AAG08319.1 - 2.4e-25 88.5 0.3 3.1e-25 88.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 HhH-GPD PF00730.25 AAG08319.1 - 0.1 13.1 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Ribosomal_S6 PF01250.17 AAG08320.1 - 5.6e-27 93.8 0.1 8e-27 93.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 SpoU_methylase PF00588.19 AAG08321.1 - 2.7e-40 137.8 0.0 3.5e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AAG08321.1 - 8.3e-21 74.1 0.0 6.3e-19 68.0 0.0 2.2 1 1 1 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding RNB PF00773.19 AAG08322.1 - 3.4e-110 368.4 0.0 5.7e-110 367.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain CSD2 PF17876.1 AAG08322.1 - 1.5e-25 89.1 0.1 1.4e-22 79.7 0.3 2.6 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 AAG08322.1 - 2e-24 85.0 1.0 6.4e-22 77.0 0.3 2.7 2 0 0 2 2 2 2 Ribonuclease B OB domain S1 PF00575.23 AAG08322.1 - 3.5e-11 43.3 0.1 7.4e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HTH_12 PF08461.10 AAG08322.1 - 1.9e-08 34.1 0.2 4.9e-08 32.8 0.2 1.7 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain RNase_II_C_S1 PF18614.1 AAG08322.1 - 0.00033 20.5 3.2 0.054 13.5 0.5 3.4 3 0 0 3 3 3 2 RNase II-type exonuclease C-terminal S1 domain OB_Dis3 PF17849.1 AAG08322.1 - 0.00065 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Adenylsucc_synt PF00709.21 AAG08323.1 - 5.1e-179 595.6 0.0 5.9e-179 595.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase tRNA-synt_His PF13393.6 AAG08324.1 - 4.7e-118 394.0 0.1 5.6e-118 393.7 0.1 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase DUF2065 PF09838.9 AAG08325.1 - 3.1e-21 75.1 4.3 3.4e-21 75.0 4.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2065) YSIRK_signal PF04650.17 AAG08325.1 - 0.37 10.7 1.4 0.73 9.7 1.4 1.5 1 0 0 1 1 1 0 YSIRK type signal peptide Band_7 PF01145.25 AAG08326.1 - 1.9e-29 103.0 1.1 1.9e-29 103.0 1.1 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AAG08326.1 - 0.037 13.7 0.1 0.084 12.6 0.1 1.6 1 1 1 2 2 2 0 SPFH domain-Band 7 family Vpu PF00558.19 AAG08326.1 - 0.1 12.4 0.5 0.24 11.2 0.5 1.6 1 0 0 1 1 1 0 Vpu protein Band_7 PF01145.25 AAG08327.1 - 1.7e-29 103.1 8.4 3e-29 102.3 8.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family HflK_N PF12221.8 AAG08327.1 - 6e-16 58.2 13.1 1.9e-15 56.6 13.1 1.9 1 0 0 1 1 1 1 Bacterial membrane protein N terminal Band_7_1 PF13421.6 AAG08327.1 - 0.021 14.5 0.4 0.037 13.7 0.1 1.5 2 0 0 2 2 2 0 SPFH domain-Band 7 family PSII_Pbs27 PF13326.6 AAG08327.1 - 0.04 14.2 1.3 1.2 9.4 0.4 2.2 1 1 1 2 2 2 0 Photosystem II Pbs27 Serglycin PF04360.12 AAG08327.1 - 7.7 6.5 9.2 5 7.1 2.3 2.6 3 0 0 3 3 3 0 Serglycin GTP-bdg_N PF13167.6 AAG08328.1 - 6.4e-32 110.1 0.0 3.7e-31 107.6 0.0 2.1 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 AAG08328.1 - 1.5e-29 102.4 12.2 3.5e-29 101.2 12.2 1.7 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 AAG08328.1 - 1.1e-21 77.0 0.0 5.4e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAG08328.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AAG08328.1 - 0.00061 19.7 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 AAG08328.1 - 0.0039 16.7 0.0 0.044 13.2 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AAG08328.1 - 0.01 15.4 0.0 4.2 6.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MnmE_helical PF12631.7 AAG08328.1 - 0.021 15.0 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 MnmE helical domain MMR_HSR1_Xtn PF16897.5 AAG08328.1 - 0.022 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 AAG08328.1 - 0.022 15.3 0.0 0.16 12.5 0.0 2.2 1 1 1 2 2 2 0 ABC transporter Dynamin_N PF00350.23 AAG08328.1 - 0.029 14.4 0.0 0.12 12.4 0.0 1.9 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 AAG08328.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Hfq PF17209.3 AAG08329.1 - 1.6e-31 107.7 0.2 1.9e-31 107.5 0.2 1.0 1 0 0 1 1 1 1 Hfq protein LSM PF01423.22 AAG08329.1 - 0.0021 17.7 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain IPPT PF01715.17 AAG08330.1 - 2.1e-87 292.7 0.1 2.5e-87 292.4 0.1 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 AAG08330.1 - 2.9e-07 30.1 0.0 0.0045 16.4 0.0 2.1 2 0 0 2 2 2 2 Isopentenyl transferase AAA_33 PF13671.6 AAG08330.1 - 4.4e-05 23.7 0.0 0.00017 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 AAG08330.1 - 0.09 12.5 0.4 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_16 PF13191.6 AAG08330.1 - 0.1 13.0 2.6 0.91 9.9 2.6 2.5 1 1 0 1 1 1 0 AAA ATPase domain MCR_beta PF02241.18 AAG08330.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Zeta_toxin PF06414.12 AAG08330.1 - 0.13 11.5 0.0 0.35 10.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin MutL_C PF08676.11 AAG08331.1 - 1.2e-51 174.3 0.2 2.1e-51 173.6 0.2 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 AAG08331.1 - 9.2e-41 138.3 0.0 1.5e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 AAG08331.1 - 4.4e-09 36.3 0.0 7.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAG08331.1 - 2.8e-06 27.8 0.0 5.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidase_3 PF01520.18 AAG08332.1 - 1.4e-46 158.8 0.0 2e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 AAG08332.1 - 9e-23 80.2 0.1 1.7e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 AMIN domain LysM PF01476.20 AAG08332.1 - 9e-12 44.9 0.0 1.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 LysM domain TsaE PF02367.17 AAG08333.1 - 2.1e-39 134.4 0.0 2.5e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAG08333.1 - 0.0036 17.5 0.0 0.0042 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG08333.1 - 0.0054 17.0 0.0 0.0068 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG08333.1 - 0.018 15.5 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AAG08333.1 - 0.085 13.3 0.0 0.093 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAG08333.1 - 0.097 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 AAG08333.1 - 0.14 11.3 0.3 0.18 10.9 0.3 1.1 1 0 0 1 1 1 0 NB-ARC domain Carb_kinase PF01256.17 AAG08334.1 - 5.1e-60 203.0 2.1 5.1e-60 203.0 2.1 1.7 2 0 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.15 AAG08334.1 - 5.4e-40 137.1 3.8 1.4e-39 135.7 3.8 1.7 1 0 0 1 1 1 1 YjeF-related protein N-terminus HK PF02110.15 AAG08334.1 - 0.0017 17.8 0.2 0.0017 17.8 0.2 1.6 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMEM65 PF10507.9 AAG08334.1 - 0.014 15.4 0.3 0.057 13.4 0.3 2.0 1 0 0 1 1 1 0 Transmembrane protein 65 Phos_pyr_kin PF08543.12 AAG08334.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF1730 PF08331.10 AAG08335.1 - 5.4e-25 87.1 0.0 9.2e-25 86.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 AAG08335.1 - 1.1e-19 71.1 1.6 1.7e-19 70.5 1.6 1.3 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAG08335.1 - 1.5e-06 28.7 3.9 3.9e-06 27.4 3.9 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG08335.1 - 4.3e-06 26.7 2.7 0.02 15.0 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG08335.1 - 0.00011 22.2 0.6 0.037 14.2 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG08335.1 - 0.00022 21.2 6.8 0.14 12.3 2.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 AAG08335.1 - 0.00076 19.2 9.5 0.0027 17.4 2.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAG08335.1 - 0.00088 19.2 11.3 0.003 17.6 3.6 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_21 PF14697.6 AAG08335.1 - 0.0036 17.4 5.1 0.93 9.7 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG08335.1 - 0.18 12.4 7.5 5.8 7.7 2.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AAG08335.1 - 0.28 11.6 9.9 4.3 7.8 9.9 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAG08335.1 - 0.61 11.1 9.8 4.1 8.6 3.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AAG08335.1 - 4.1 8.0 7.0 21 5.8 7.0 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain RNase_T PF00929.24 AAG08336.1 - 4.6e-34 118.4 0.0 5.1e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAG08336.1 - 3.7e-05 23.8 0.0 5.5e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like RsgA_GTPase PF03193.16 AAG08337.1 - 5.9e-53 179.2 0.0 9.1e-53 178.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAG08337.1 - 8.9e-07 29.0 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAG08337.1 - 8.7e-06 25.3 0.1 0.0038 16.8 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_29 PF13555.6 AAG08337.1 - 0.0063 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAG08337.1 - 0.0064 17.0 0.1 0.012 16.2 0.1 1.3 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 AAG08337.1 - 0.014 14.9 0.0 0.15 11.6 0.0 2.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain SMC_N PF02463.19 AAG08337.1 - 0.018 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG08337.1 - 0.027 14.9 1.9 0.028 14.8 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 AAG08337.1 - 0.13 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AAG08337.1 - 0.15 11.7 0.0 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 Ras family AAA_23 PF13476.6 AAG08337.1 - 0.23 12.0 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAG08337.1 - 0.23 10.9 0.2 0.38 10.3 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 AAG08337.1 - 0.23 11.0 0.3 16 5.1 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 AAG08337.1 - 0.48 10.5 2.1 1.2 9.2 0.8 2.0 1 1 0 2 2 2 0 Dynamin family MotB_plug PF13677.6 AAG08338.1 - 1.8e-17 62.6 0.1 3.5e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AAG08338.1 - 1.1e-14 54.6 0.0 5.3e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 OmpA family MotA_ExbB PF01618.16 AAG08339.1 - 3.3e-10 39.8 0.2 6.4e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family FAM220 PF15487.6 AAG08339.1 - 0.12 12.0 0.0 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 FAM220 family MASE1 PF05231.14 AAG08339.1 - 0.21 10.7 4.0 2.6 7.1 0.2 2.2 2 0 0 2 2 2 0 MASE1 HDOD PF08668.12 AAG08340.1 - 3.2e-13 49.6 0.6 6.3e-13 48.6 0.6 1.5 1 0 0 1 1 1 1 HDOD domain Rhodanese PF00581.20 AAG08341.1 - 5.5e-33 113.7 0.0 1.4e-16 60.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain PS_Dcarbxylase PF02666.15 AAG08342.1 - 3.1e-60 203.2 0.0 3.8e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PilZ PF07238.14 AAG08343.1 - 0.13 12.6 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 PilZ domain EAL PF00563.20 AAG08344.1 - 1.9e-58 197.8 0.7 4.2e-58 196.7 0.7 1.6 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG08344.1 - 3.8e-19 69.0 0.1 9e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AAG08344.1 - 3.9e-07 30.1 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG08344.1 - 3.1e-05 24.2 0.0 0.0001 22.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAG08344.1 - 0.0039 17.4 0.1 0.24 11.7 0.0 2.9 3 0 0 3 3 3 1 PAS fold Response_reg PF00072.24 AAG08344.1 - 0.009 16.2 0.0 0.036 14.2 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 AAG08344.1 - 0.01 15.8 0.0 0.048 13.7 0.0 2.2 1 0 0 1 1 1 0 PAS domain ACT_6 PF13740.6 AAG08345.1 - 1.6e-28 98.5 0.2 2.1e-26 91.7 0.2 2.7 2 0 0 2 2 2 1 ACT domain HAD PF12710.7 AAG08345.1 - 2.4e-25 90.0 0.4 3.8e-25 89.4 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG08345.1 - 1.4e-18 68.0 2.6 1.7e-18 67.7 1.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAG08345.1 - 3.1e-12 46.8 0.0 1.6e-10 41.2 0.0 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase ACT PF01842.25 AAG08345.1 - 6.3e-08 32.3 1.3 1.9e-07 30.7 0.5 2.3 2 0 0 2 2 2 1 ACT domain HAD_2 PF13419.6 AAG08345.1 - 7.1e-05 23.0 0.1 0.0006 19.9 0.1 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ACT_4 PF13291.6 AAG08345.1 - 0.00018 22.0 0.0 0.00047 20.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain Put_Phosphatase PF06888.12 AAG08345.1 - 0.00091 18.7 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase HHH_5 PF14520.6 AAG08345.1 - 0.029 15.0 0.8 1.7 9.3 0.2 3.3 3 1 0 3 3 3 0 Helix-hairpin-helix domain ACT_7 PF13840.6 AAG08345.1 - 0.057 13.2 0.4 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 ACT domain SMP_2 PF10144.9 AAG08346.1 - 1.6e-08 34.4 4.7 6e-08 32.5 4.7 1.9 1 1 0 1 1 1 1 Bacterial virulence factor haemolysin CHASE8 PF17152.4 AAG08346.1 - 0.031 14.5 0.2 0.074 13.3 0.2 1.7 1 0 0 1 1 1 0 Periplasmic sensor domain tRNA_anti-like PF12869.7 AAG08346.1 - 0.13 11.8 0.6 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 tRNA_anti-like Yip1 PF04893.17 AAG08346.1 - 4.8 6.9 6.9 3.2 7.5 1.2 2.1 2 0 0 2 2 2 0 Yip1 domain YdjM PF04307.14 AAG08347.1 - 1.4e-29 102.6 14.5 1.6e-29 102.4 14.5 1.0 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase ABC_trans_aux PF03886.13 AAG08348.1 - 3.8e-38 130.6 1.9 4.9e-38 130.3 1.9 1.1 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component LptE PF04390.12 AAG08348.1 - 0.1 13.3 0.1 0.22 12.2 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide-assembly DNA_topoisoIV PF00521.20 AAG08349.1 - 1.9e-132 442.2 0.0 2.3e-132 441.9 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AAG08349.1 - 5.7e-13 48.1 0.1 3e-05 23.4 0.0 4.5 4 0 0 4 4 4 2 DNA gyrase C-terminal domain, beta-propeller gag-asp_proteas PF13975.6 AAG08350.1 - 6.4e-24 84.3 0.1 8.2e-24 84.0 0.1 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AAG08350.1 - 1.4e-20 73.7 0.4 1.9e-20 73.3 0.4 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 AAG08350.1 - 0.0046 17.2 0.0 0.0098 16.2 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Phytase-like PF13449.6 AAG08351.1 - 1.5e-12 48.1 0.0 3.3e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 AAG08351.1 - 1.2e-05 24.6 0.0 0.036 13.3 0.0 2.7 3 0 0 3 3 3 2 SdiA-regulated DNA_gyraseB PF00204.25 AAG08352.1 - 8.8e-39 132.8 0.0 1.5e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 AAG08352.1 - 9e-24 83.4 1.1 1.8e-23 82.5 1.1 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AAG08352.1 - 1.4e-17 64.2 0.1 2.3e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AAG08352.1 - 9.4e-12 45.1 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 AAG08352.1 - 0.00048 20.0 0.0 0.00091 19.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAG08352.1 - 0.055 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain TOPRIM_C PF16898.5 AAG08352.1 - 0.073 13.4 0.0 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM UPF0227 PF05728.12 AAG08353.1 - 2.1e-70 236.5 0.0 2.4e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 AAG08353.1 - 3e-05 24.7 9.8 5.3e-05 23.9 9.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AAG08353.1 - 0.0005 20.0 0.2 0.00093 19.1 0.2 1.5 1 1 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 AAG08353.1 - 0.0041 16.4 0.1 0.0081 15.4 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cys_rich_FGFR PF00839.17 AAG08353.1 - 0.22 11.7 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Cysteine rich repeat Metallophos PF00149.28 AAG08354.1 - 3.3e-13 50.6 0.0 5.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAG08354.1 - 1.6e-09 38.2 0.0 5.7e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1249 PF06853.12 AAG08355.1 - 3.9e-44 149.4 0.0 4.6e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1249) PhnJ PF06007.11 AAG08355.1 - 0.077 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ zinc_ribbon_16 PF17034.5 AAG08355.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon like family NUDIX PF00293.28 AAG08356.1 - 5.9e-15 55.5 0.1 8.6e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF3298 PF11738.8 AAG08357.1 - 2.1e-06 28.6 0.1 2.3e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3298) PdaC PF13739.6 AAG08357.1 - 7.7e-06 26.8 0.0 3.1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Deacetylase PdaC ThiC_Rad_SAM PF01964.18 AAG08358.1 - 5.6e-200 664.5 0.0 6.5e-200 664.2 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 AAG08358.1 - 3.3e-34 116.5 0.1 7.1e-34 115.5 0.1 1.6 1 0 0 1 1 1 1 ThiC-associated domain OEP PF02321.18 AAG08359.1 - 5.5e-55 186.1 40.9 1.9e-30 106.1 16.7 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Flavodoxin_2 PF02525.17 AAG08360.1 - 2.9e-54 183.8 0.0 3.3e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAG08360.1 - 3.5e-14 52.8 0.0 5.8e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Aminotran_1_2 PF00155.21 AAG08361.1 - 1.7e-71 241.4 0.0 1.9e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAG08361.1 - 1.2e-07 31.4 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAG08361.1 - 1e-05 24.7 0.0 2.4e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAG08361.1 - 4.7e-05 22.1 0.0 6.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Adeno_VII PF03228.14 AAG08361.1 - 0.0078 16.9 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 Adenoviral core protein VII TPP_enzyme_N PF02776.18 AAG08362.1 - 2.8e-54 183.3 0.2 2.8e-54 183.3 0.2 3.0 4 0 0 4 4 4 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG08362.1 - 9.2e-29 99.9 0.0 3.5e-28 98.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AAG08362.1 - 3.9e-28 98.2 0.0 1.1e-27 96.7 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ATP-grasp_5 PF13549.6 AAG08363.1 - 2e-50 171.3 0.0 3e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AAG08363.1 - 4.5e-34 117.2 0.2 1.2e-33 115.8 0.1 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAG08363.1 - 1.1e-12 48.4 0.0 3.6e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 AAG08363.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Acyl-CoA_dh_1 PF00441.24 AAG08364.1 - 9e-52 175.3 4.1 1.3e-51 174.8 4.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG08364.1 - 1.5e-25 89.2 0.0 2.5e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG08364.1 - 6.7e-25 87.9 1.9 2.1e-23 83.1 0.5 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG08364.1 - 1.2e-18 67.8 0.3 2.9e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 AAG08364.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal ECH_1 PF00378.20 AAG08365.1 - 2e-50 171.5 0.0 2.3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAG08365.1 - 2.2e-35 122.7 0.1 6.7e-32 111.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AA_permease PF00324.21 AAG08366.1 - 5e-116 388.1 45.1 6.1e-116 387.8 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG08366.1 - 8.5e-42 143.5 45.5 1.1e-41 143.0 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease OAD_gamma PF04277.13 AAG08366.1 - 0.14 12.8 1.1 2.2 8.9 0.6 3.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain HATPase_c PF02518.26 AAG08367.1 - 1.2e-32 112.7 0.1 2e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAG08367.1 - 1.6e-22 79.8 0.0 2.9e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAG08367.1 - 1.6e-16 60.0 1.7 1.6e-16 60.0 1.7 3.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE5 PF17149.4 AAG08367.1 - 4.3e-15 55.5 0.0 8.6e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Periplasmic sensor domain found in signal transduction proteins Hpt PF01627.23 AAG08367.1 - 1e-07 32.1 3.7 1e-07 32.1 3.7 3.6 2 1 1 3 3 3 1 Hpt domain HAMP PF00672.25 AAG08367.1 - 5.5e-06 26.7 0.4 5.5e-06 26.7 0.4 2.4 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 AAG08367.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAG08368.1 - 3.1e-25 88.5 0.0 5.2e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG08368.1 - 3.4e-22 78.3 0.1 7.3e-22 77.2 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal TetR_C_6 PF13977.6 AAG08369.1 - 1.2e-25 90.0 1.8 1.2e-25 90.0 1.8 1.6 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 AAG08369.1 - 3.9e-13 49.0 0.0 8e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family SBP_bac_8 PF13416.6 AAG08370.1 - 2e-40 139.4 0.4 2.4e-40 139.1 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAG08370.1 - 2.2e-10 40.4 0.5 4.2e-10 39.4 0.4 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG08370.1 - 1.2e-05 25.4 4.7 3.8e-05 23.8 4.6 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Oxidored_FMN PF00724.20 AAG08371.1 - 1e-58 199.3 0.0 1.2e-58 199.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AAG08371.1 - 8.8e-11 41.6 0.7 2.5e-10 40.1 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG08371.1 - 5.9e-07 29.2 4.0 8.5e-07 28.7 4.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG08371.1 - 1.6e-06 27.5 0.4 2.8e-06 26.7 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAG08371.1 - 1.8e-06 28.4 0.2 0.0029 18.1 1.2 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG08371.1 - 1.7e-05 23.7 2.7 2.9e-05 23.0 2.7 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 AAG08371.1 - 3e-05 24.2 3.6 3.2e-05 24.1 0.9 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AAG08371.1 - 6.4e-05 22.2 1.0 0.0001 21.5 1.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAG08371.1 - 0.0031 16.8 0.1 0.0055 16.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 AAG08371.1 - 0.0075 15.9 5.6 0.61 9.6 3.1 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAG08371.1 - 0.11 12.4 0.4 1.7 8.5 0.4 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 AAG08371.1 - 0.12 11.7 0.2 0.23 10.7 0.2 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 AAG08371.1 - 0.19 12.1 0.3 1.6 9.2 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 AAG08371.1 - 0.19 10.9 1.1 0.46 9.7 0.6 1.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG08371.1 - 1 8.6 5.5 0.12 11.6 1.4 1.5 2 0 0 2 2 2 0 FAD binding domain Cupin_2 PF07883.11 AAG08372.1 - 3.7e-18 65.0 0.0 5.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 AAG08372.1 - 3.2e-11 43.1 0.1 4.7e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAG08372.1 - 1e-10 41.8 0.4 1.9e-10 40.9 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG08372.1 - 5.5e-09 35.9 0.0 8.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding_2 PF14525.6 AAG08372.1 - 0.00053 19.7 0.0 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 AraC-binding-like domain AraC_binding PF02311.19 AAG08372.1 - 0.00094 19.1 0.3 0.0014 18.5 0.3 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_25 PF13413.6 AAG08372.1 - 0.0012 18.7 0.5 0.0035 17.2 0.5 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAG08372.1 - 0.0014 18.1 0.8 0.017 14.6 0.1 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_37 PF13744.6 AAG08372.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAG08372.1 - 0.0078 16.6 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_35 PF13693.6 AAG08372.1 - 0.02 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cupin_3 PF05899.12 AAG08372.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF896 PF05979.12 AAG08372.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) MannoseP_isomer PF01050.18 AAG08372.1 - 0.22 11.4 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Glycos_transf_N PF04413.16 AAG08373.1 - 3.5e-69 232.0 0.1 8.2e-69 230.8 0.0 1.6 2 0 0 2 2 2 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Glycos_transf_1 PF00534.20 AAG08373.1 - 0.00059 19.4 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 AAG08373.1 - 0.083 11.7 0.0 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase LysR_substrate PF03466.20 AAG08374.1 - 1.7e-30 105.9 8.2 1.7e-30 105.9 8.2 1.7 2 1 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08374.1 - 9.6e-20 70.3 1.2 2.1e-19 69.2 1.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Multi_Drug_Res PF00893.19 AAG08375.1 - 6.1e-25 87.7 8.5 7.8e-25 87.4 8.5 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAG08375.1 - 0.00099 19.3 13.3 0.0012 19.1 13.3 1.2 1 0 0 1 1 1 1 EamA-like transporter family UPF0060 PF02694.15 AAG08375.1 - 0.091 13.0 7.5 0.1 12.9 7.5 1.2 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family EmrE PF13536.6 AAG08375.1 - 0.3 10.6 8.9 0.44 10.1 8.9 1.2 1 1 0 1 1 1 0 Putative multidrug resistance efflux transporter DUF4191 PF13829.6 AAG08375.1 - 6.5 6.0 8.5 2.3 7.5 6.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3188 PF11384.8 AAG08375.1 - 8.8 6.1 14.9 3.8 7.3 8.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) DAO PF01266.24 AAG08376.1 - 1.7e-19 70.7 3.6 2.1e-19 70.3 3.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAG08376.1 - 1.2e-05 24.7 0.7 0.00012 21.4 0.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG08376.1 - 1.2e-05 24.6 2.9 1.2e-05 24.6 2.9 2.0 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAG08376.1 - 0.00022 21.4 2.3 0.00022 21.4 2.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AAG08376.1 - 0.00063 18.9 0.6 0.036 13.1 0.3 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 AAG08376.1 - 0.0024 17.2 1.2 0.0046 16.3 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 AAG08376.1 - 0.027 13.8 2.9 0.039 13.3 2.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 AAG08376.1 - 0.092 12.0 0.2 0.35 10.1 0.5 1.7 2 0 0 2 2 2 0 Thi4 family Aldo_ket_red PF00248.21 AAG08377.1 - 8.8e-33 113.8 0.0 3e-31 108.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Acyl-CoA_dh_1 PF00441.24 AAG08379.1 - 1.2e-40 139.1 1.1 1.9e-40 138.5 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG08379.1 - 1.2e-23 83.1 0.2 2.1e-23 82.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAG08379.1 - 1.4e-11 44.8 1.7 1.4e-11 44.8 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG08379.1 - 0.0019 18.9 0.3 0.0062 17.2 0.3 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF2270 PF10028.9 AAG08379.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) Acyl-CoA_dh_1 PF00441.24 AAG08380.1 - 1.3e-30 106.6 3.8 1.3e-30 106.6 3.8 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAG08380.1 - 3.5e-20 72.7 0.4 1.6e-18 67.4 0.1 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAG08380.1 - 9e-17 61.6 1.8 2.1e-16 60.4 1.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG08380.1 - 3.2e-10 40.1 0.0 5.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain PfkB PF00294.24 AAG08381.1 - 8.4e-49 166.5 0.8 1.1e-48 166.1 0.8 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 AAG08381.1 - 1.4e-16 61.0 0.0 3.3e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 AAG08381.1 - 9.2e-10 38.3 0.1 1.1e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase ATP-synt_C PF00137.21 AAG08381.1 - 0.021 15.2 0.4 0.021 15.2 0.4 2.1 2 0 0 2 2 2 0 ATP synthase subunit C ABC_membrane PF00664.23 AAG08382.1 - 1.2e-48 166.2 8.2 1.7e-48 165.6 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAG08382.1 - 8.9e-33 113.7 0.0 1.6e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAG08382.1 - 3.2e-09 36.5 0.2 3.7e-07 29.8 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAG08382.1 - 8.7e-05 22.8 0.1 0.0007 19.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG08382.1 - 0.00012 22.5 1.5 0.00052 20.4 1.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 AAG08382.1 - 0.00013 20.9 0.2 0.0011 17.8 0.1 2.4 2 1 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AAG08382.1 - 0.0018 18.2 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase DUF2075 PF09848.9 AAG08382.1 - 0.0021 17.3 0.1 0.0036 16.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 AAG08382.1 - 0.0039 16.9 0.3 0.028 14.1 0.3 2.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAG08382.1 - 0.0079 16.3 0.1 0.02 14.9 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 AAG08382.1 - 0.0081 15.9 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DEAD PF00270.29 AAG08382.1 - 0.019 14.7 0.0 0.06 13.1 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.22 AAG08382.1 - 0.048 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 AAG08382.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 AAG08382.1 - 0.089 12.7 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 AAG08382.1 - 0.1 11.8 0.0 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 AAG08382.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 AAG08382.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAG08382.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF3671 PF12420.8 AAG08382.1 - 2.6 8.1 4.8 0.36 10.9 0.3 1.8 2 0 0 2 2 1 0 Protein of unknown function APH PF01636.23 AAG08383.1 - 3.1e-05 24.0 3.1 0.0013 18.7 3.1 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 AAG08383.1 - 0.00092 18.6 0.1 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Wzy_C PF04932.15 AAG08384.1 - 1.3e-10 41.2 11.9 1.3e-10 41.2 11.9 4.8 3 2 0 3 3 3 1 O-Antigen ligase TMEM252 PF15664.5 AAG08384.1 - 0.032 14.0 0.2 0.057 13.1 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 252 family Glycos_transf_2 PF00535.26 AAG08385.1 - 2.1e-29 102.5 0.0 4.4e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAG08385.1 - 3.4e-17 63.1 0.0 4.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAG08385.1 - 2.8e-09 36.9 0.0 7.3e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAG08385.1 - 1.9e-06 27.9 0.0 3.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 AAG08385.1 - 0.006 17.1 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAG08385.1 - 0.029 13.8 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 ZoocinA_TRD PF16775.5 AAG08385.1 - 0.15 12.3 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme Glyco_trans_1_2 PF13524.6 AAG08386.1 - 9.6e-09 35.5 0.2 2.6e-08 34.1 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG08386.1 - 0.019 15.4 0.0 0.065 13.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 PIG-L PF02585.17 AAG08387.1 - 3.5e-13 50.3 0.0 5.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Mig-14 PF07395.11 AAG08388.1 - 1.1e-143 477.4 0.0 1.2e-143 477.2 0.0 1.0 1 0 0 1 1 1 1 Mig-14 Acetyltransf_6 PF13480.7 AAG08388.1 - 5.2e-14 52.6 1.2 5.2e-14 52.6 1.2 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF2249 PF10006.9 AAG08388.1 - 0.026 14.4 0.0 0.085 12.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) MRP-S23 PF10484.9 AAG08388.1 - 0.083 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 Glycos_transf_1 PF00534.20 AAG08389.1 - 4.2e-30 104.5 0.0 1.9e-29 102.4 0.0 1.8 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG08389.1 - 1.1e-24 87.4 0.1 3.2e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG08389.1 - 6.1e-10 39.4 0.1 4.5e-09 36.5 0.2 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAG08389.1 - 0.0028 18.0 0.1 0.0059 17.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Carbam_trans_C PF16861.5 AAG08390.1 - 1e-61 207.5 0.0 1.7e-61 206.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 AAG08390.1 - 2.2e-57 195.3 0.0 2.9e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Kdo PF06293.14 AAG08391.1 - 7.7e-15 54.8 0.3 4e-09 36.1 0.0 2.5 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AAG08391.1 - 7e-09 36.0 21.3 0.002 18.1 0.6 4.3 1 1 2 3 3 3 3 Phosphotransferase enzyme family Pkinase PF00069.25 AAG08391.1 - 0.0039 16.6 0.0 0.93 8.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 AAG08392.1 - 2.1e-70 236.3 0.1 2.5e-70 236.1 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kdo PF06293.14 AAG08393.1 - 1.2e-17 64.0 0.5 1.5e-17 63.7 0.5 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 AAG08393.1 - 0.00011 21.8 1.7 0.0013 18.4 0.1 2.6 1 1 1 2 2 2 1 RIO1 family Pkinase PF00069.25 AAG08393.1 - 0.00017 21.1 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAG08393.1 - 0.00032 20.1 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AAG08393.1 - 0.00078 19.4 7.5 0.002 18.1 3.4 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAG08393.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 AAG08394.1 - 1.8e-71 239.8 0.1 2.2e-71 239.5 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glycos_transf_1 PF00534.20 AAG08395.1 - 4.3e-32 111.0 0.0 6.1e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG08395.1 - 1.8e-14 54.3 0.0 2.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG08395.1 - 6.4e-07 29.5 0.1 6.4e-06 26.3 0.1 2.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAG08395.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAG08395.1 - 0.095 13.1 2.1 0.16 12.4 0.3 2.4 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain Glycogen_syn PF05693.13 AAG08395.1 - 0.23 9.9 0.0 0.45 9.0 0.0 1.4 2 0 0 2 2 2 0 Glycogen synthase Glyco_transf_9 PF01075.17 AAG08396.1 - 9.2e-85 283.9 0.0 1.1e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Thioredoxin_9 PF14595.6 AAG08396.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Glyco_transf_9 PF01075.17 AAG08397.1 - 5.1e-91 304.4 0.0 6.1e-91 304.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) PS_pyruv_trans PF04230.13 AAG08397.1 - 0.18 11.7 0.0 4.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase Aminotran_4 PF01063.19 AAG08398.1 - 1.4e-54 185.4 0.0 1.6e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV FNIP_N PF14636.6 AAG08398.1 - 0.028 15.4 0.1 0.083 13.9 0.0 1.7 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus GlnE PF03710.15 AAG08399.1 - 3.5e-193 639.2 0.5 5.1e-97 324.2 0.2 2.3 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 AAG08399.1 - 3.6e-59 199.0 3.9 1.9e-44 151.3 1.0 3.0 2 0 0 2 2 2 2 GlnD PII-uridylyltransferase ParBc PF02195.18 AAG08399.1 - 0.058 13.7 0.8 14 6.1 0.4 3.0 2 0 0 2 2 2 0 ParB-like nuclease domain PDH_E1_M PF17831.1 AAG08400.1 - 1.9e-117 390.8 0.1 3.1e-117 390.1 0.1 1.3 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 AAG08400.1 - 6.3e-14 51.7 0.0 4.6e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 AAG08400.1 - 0.00013 21.9 0.0 0.00051 19.9 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF3135 PF11333.8 AAG08400.1 - 0.19 12.0 0.0 0.55 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) 2-oxoacid_dh PF00198.23 AAG08401.1 - 1.8e-76 256.7 0.0 2.4e-76 256.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAG08401.1 - 2.5e-47 158.6 12.1 1.9e-23 82.1 3.9 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAG08401.1 - 2.1e-16 59.5 7.4 8.4e-05 22.3 0.2 4.8 2 2 2 4 4 4 4 Biotin-lipoyl like E3_binding PF02817.17 AAG08401.1 - 2.3e-15 56.6 0.0 6.3e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain GCV_H PF01597.19 AAG08401.1 - 3.6e-08 33.3 6.4 0.00048 20.0 1.2 2.5 2 0 0 2 2 2 2 Glycine cleavage H-protein RnfC_N PF13375.6 AAG08401.1 - 3.2e-07 30.2 3.8 0.008 16.1 0.1 3.1 2 1 1 3 3 3 2 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 AAG08401.1 - 3.5e-07 29.7 1.7 0.97 8.6 0.0 4.2 2 2 2 4 4 4 3 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 AAG08401.1 - 1.7e-06 27.6 2.7 0.9 9.2 0.0 4.4 3 1 0 4 4 4 2 Pyrimidine nucleoside phosphorylase C-terminal domain NQRA PF05896.11 AAG08401.1 - 6.1e-05 22.6 1.0 0.23 10.8 0.1 2.5 2 0 0 2 2 2 2 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PTS_EIIA_1 PF00358.20 AAG08401.1 - 0.00018 21.3 2.0 1.1 9.0 0.0 4.0 2 2 2 4 4 4 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 HlyD_3 PF13437.6 AAG08401.1 - 0.00031 21.4 7.9 0.3 11.8 1.8 3.9 1 1 1 3 3 3 2 HlyD family secretion protein DUF2118 PF09891.9 AAG08401.1 - 0.19 11.7 0.4 21 5.0 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) DEC-1_N PF04625.13 AAG08401.1 - 0.22 10.5 15.4 1 8.3 4.1 2.3 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region YqfD PF06898.11 AAG08401.1 - 2.2 7.0 5.1 5.6 5.7 0.1 3.2 2 2 1 3 3 3 0 Putative stage IV sporulation protein YqfD DUF3597 PF12200.8 AAG08401.1 - 7 7.2 15.1 11 6.6 3.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) EAL PF00563.20 AAG08402.1 - 2.2e-78 263.0 1.0 3.3e-78 262.5 0.1 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AAG08402.1 - 5.6e-40 136.7 0.0 1.7e-39 135.2 0.0 1.9 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAG08402.1 - 1.4e-15 57.4 0.0 8.1e-15 55.0 0.0 2.2 2 0 0 2 2 2 1 PAS domain GAF PF01590.26 AAG08402.1 - 1.8e-13 51.3 0.5 5.4e-13 49.7 0.1 2.1 2 0 0 2 2 2 1 GAF domain PAS PF00989.25 AAG08402.1 - 2.7e-13 49.9 0.0 1.3e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAG08402.1 - 7.9e-13 48.6 0.1 3.4e-11 43.4 0.0 3.0 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 AAG08402.1 - 3.5e-12 46.8 0.6 2.4e-11 44.1 0.6 2.5 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.12 AAG08402.1 - 5.8e-12 45.7 0.0 1.2e-06 28.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAG08402.1 - 4.2e-06 26.7 0.1 2.3e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain Nre_C PF04895.12 AAG08402.1 - 0.0092 15.9 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 3 1 Archaeal Nre, C-terminal HK_sensor PF16750.5 AAG08402.1 - 0.017 15.4 0.0 0.073 13.4 0.0 2.1 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase PMSR PF01625.21 AAG08403.1 - 3.3e-64 215.7 0.4 3.9e-64 215.5 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase RsmJ PF04378.13 AAG08404.1 - 2.4e-112 374.1 0.1 2.8e-112 373.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ GGDEF_2 PF17853.1 AAG08404.1 - 0.041 14.1 0.2 0.085 13.1 0.2 1.6 1 0 0 1 1 1 0 GGDEF-like domain Cons_hypoth95 PF03602.15 AAG08404.1 - 0.042 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Acyl-CoA_dh_C PF12806.7 AAG08405.1 - 8.6e-30 103.4 0.7 1.8e-29 102.4 0.1 1.8 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAG08405.1 - 2.4e-18 66.8 0.0 1.6e-17 64.1 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG08405.1 - 1e-14 54.5 0.0 2.3e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG08405.1 - 1.2e-10 42.0 0.0 3.3e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 AAG08405.1 - 1.9e-08 34.2 0.0 4.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 AAG08405.1 - 0.00069 19.9 0.1 0.0045 17.2 0.0 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Na_H_Exchanger PF00999.21 AAG08406.1 - 1.6e-51 175.3 37.0 1.9e-51 175.0 37.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_C PF02080.21 AAG08406.1 - 1e-11 44.5 0.0 2.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-C domain CorC_HlyC PF03471.17 AAG08406.1 - 7.7e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Transporter associated domain MscS_TM PF12794.7 AAG08407.1 - 9.3e-106 353.5 19.4 1.8e-105 352.5 19.4 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 MscS_porin PF12795.7 AAG08407.1 - 2e-56 191.2 38.8 2e-56 191.2 38.8 3.1 2 1 1 3 3 3 1 Mechanosensitive ion channel porin domain MS_channel PF00924.18 AAG08407.1 - 5e-52 176.4 0.5 1.5e-51 174.9 0.5 1.9 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF3810 PF12725.7 AAG08407.1 - 2.3 7.5 6.4 18 4.6 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) UPF0061 PF02696.14 AAG08408.1 - 8.6e-151 502.9 0.0 1e-150 502.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Sfi1 PF08457.10 AAG08408.1 - 0.0057 15.3 0.3 0.0089 14.6 0.3 1.2 1 0 0 1 1 1 1 Sfi1 spindle body protein TauE PF01925.19 AAG08409.1 - 2.4e-35 122.3 28.0 2.8e-35 122.1 28.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Cys_Met_Meta_PP PF01053.20 AAG08410.1 - 2e-144 480.9 0.0 2.2e-144 480.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AAG08410.1 - 4.5e-11 42.5 0.1 7.5e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAG08410.1 - 1.8e-10 40.7 1.1 1.8e-10 40.7 1.1 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAG08410.1 - 1.4e-07 30.8 0.5 2.3e-07 30.1 0.5 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAG08410.1 - 0.00063 19.1 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 AAG08410.1 - 0.001 18.0 0.1 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 AAG08410.1 - 0.025 13.1 0.1 0.36 9.3 0.0 2.1 2 0 0 2 2 2 0 Methionine gamma-lyase DUF4442 PF14539.6 AAG08411.1 - 7.8e-20 71.4 0.0 9.4e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) YiiD_C PF09500.10 AAG08411.1 - 5.5e-10 39.2 0.0 6.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) 4HBT PF03061.22 AAG08411.1 - 0.00026 21.3 0.0 0.00066 20.0 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily PS-DH PF14765.6 AAG08411.1 - 0.027 13.7 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase Cadherin PF00028.17 AAG08411.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Cadherin domain Usp PF00582.26 AAG08412.1 - 1.6e-39 135.6 1.8 6.4e-21 75.4 0.8 2.6 2 1 0 2 2 2 2 Universal stress protein family GAD PF02938.14 AAG08412.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 GAD domain DUF2786 PF10979.8 AAG08412.1 - 0.44 10.5 3.6 0.54 10.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) AAA_31 PF13614.6 AAG08413.1 - 1.8e-37 128.9 0.0 2.5e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAG08413.1 - 5.6e-20 71.7 0.0 8.6e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAG08413.1 - 1.4e-08 34.4 0.3 0.00011 21.6 0.1 2.1 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 AAG08413.1 - 5.5e-08 32.6 0.1 1.2e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AAG08413.1 - 8.3e-07 28.5 0.3 6.5e-06 25.5 0.1 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AAG08413.1 - 9.6e-06 25.2 0.0 0.00013 21.6 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AAG08413.1 - 2e-05 24.2 1.8 0.066 12.7 0.3 2.5 2 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 AAG08413.1 - 0.029 14.2 0.2 0.16 11.8 0.0 2.2 2 1 2 4 4 4 0 mRNA cleavage and polyadenylation factor CLP1 P-loop GP24_25 PF17388.2 AAG08413.1 - 0.1 12.6 0.1 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 LysR_substrate PF03466.20 AAG08414.1 - 2.3e-46 157.8 3.3 3.7e-46 157.1 3.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08414.1 - 1.5e-25 88.9 0.7 3.5e-25 87.7 0.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAG08414.1 - 0.0049 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAG08414.1 - 0.022 14.8 1.0 0.16 12.1 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.16 AAG08415.1 - 1.7e-49 168.7 85.8 2.3e-39 135.3 46.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG08415.1 - 1.2e-12 47.5 31.3 1.1e-09 37.7 8.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAG08415.1 - 0.16 10.8 31.5 0.045 12.6 3.0 3.5 2 2 1 3 3 3 0 MFS_1 like family Peptidase_A8 PF01252.18 AAG08415.1 - 5.3 7.3 8.2 0.45 10.8 0.9 2.8 2 1 1 3 3 3 0 Signal peptidase (SPase) II adh_short PF00106.25 AAG08416.1 - 9.4e-25 87.2 0.0 4.4e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAG08416.1 - 7.9e-17 61.6 0.0 2.8e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAG08416.1 - 8.3e-07 29.1 0.1 1.5e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG08416.1 - 0.036 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GHMP_kinases_C PF08544.13 AAG08416.1 - 0.054 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal YjeF_N PF03853.15 AAG08416.1 - 0.17 11.8 0.3 0.27 11.1 0.3 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Arabinose_bd PF12625.7 AAG08417.1 - 2.8e-37 128.6 6.6 2.8e-37 128.6 6.6 2.0 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG08417.1 - 7.1e-22 77.5 2.2 1.8e-21 76.2 2.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG08417.1 - 7.6e-09 35.5 0.0 8.6e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r4_2 PF08281.12 AAG08417.1 - 0.0073 16.0 3.5 0.73 9.6 0.0 3.0 3 0 0 3 3 3 2 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAG08417.1 - 0.019 14.5 0.3 9.1 5.9 0.1 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_r3 PF04539.16 AAG08417.1 - 0.033 14.3 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 SH3_14 PF18343.1 AAG08418.1 - 0.058 13.5 0.1 6.7 6.8 0.0 3.5 3 1 1 4 4 4 0 Dda helicase SH3 domain Cupin_3 PF05899.12 AAG08418.1 - 0.11 12.2 0.1 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) URO-D PF01208.17 AAG08419.1 - 6.8e-142 472.7 0.0 7.7e-142 472.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Fer4_20 PF14691.6 AAG08420.1 - 5e-38 129.3 0.1 7.7e-38 128.8 0.1 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AAG08420.1 - 2e-25 89.6 0.0 2.6e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG08420.1 - 2.4e-11 43.4 0.0 6.5e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG08420.1 - 3.3e-10 40.4 2.8 2.4e-05 24.8 0.2 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 AAG08420.1 - 9.9e-07 27.5 0.1 0.00024 19.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 AAG08420.1 - 2.3e-06 27.7 0.0 6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAG08420.1 - 3.3e-06 26.7 0.2 0.00016 21.2 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAG08420.1 - 1.9e-05 25.0 0.7 0.049 14.1 0.2 2.9 2 1 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.20 AAG08420.1 - 0.00026 21.1 0.0 1.3 9.1 0.0 2.9 2 1 1 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 AAG08420.1 - 0.00047 19.5 0.1 0.0008 18.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAG08420.1 - 0.00053 18.8 0.4 0.00083 18.2 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 AAG08420.1 - 0.00084 18.6 0.1 0.006 15.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 AAG08420.1 - 0.012 15.2 1.6 0.12 12.0 0.8 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 AAG08420.1 - 0.014 16.0 0.2 8.4 7.0 0.0 2.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AAG08420.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAG08420.1 - 0.024 14.0 0.5 0.84 8.9 0.1 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 AAG08420.1 - 0.14 11.2 0.3 0.58 9.2 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain AdoHcyase_NAD PF00670.21 AAG08420.1 - 0.52 10.4 2.5 24 5.0 0.1 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_2 PF00310.21 AAG08421.1 - 2.6e-173 576.6 0.0 3.5e-173 576.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 AAG08421.1 - 4e-148 493.4 0.0 9.4e-148 492.2 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 AAG08421.1 - 1.1e-100 336.7 0.0 1.6e-100 336.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 AAG08421.1 - 1.4e-77 259.6 6.4 3.1e-77 258.5 6.4 1.6 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 AAG08421.1 - 3.5e-05 23.0 0.1 6.4e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AAA_22 PF13401.6 AAG08422.1 - 1e-12 48.5 0.3 1.7e-12 47.7 0.3 1.3 1 0 0 1 1 1 1 AAA domain SPOR PF05036.13 AAG08422.1 - 8.8e-12 45.2 0.9 3e-11 43.5 0.5 2.2 2 0 0 2 2 2 1 Sporulation related domain AAA_16 PF13191.6 AAG08422.1 - 1.4e-05 25.5 5.0 0.0016 18.8 5.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAG08422.1 - 8.4e-05 22.4 0.2 0.00014 21.6 0.2 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AAG08422.1 - 0.0028 16.7 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 AAG08422.1 - 0.0043 17.1 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAG08422.1 - 0.015 15.2 0.2 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 AAG08422.1 - 0.017 14.7 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 AAG08422.1 - 0.018 15.0 0.1 0.046 13.7 0.1 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AAG08422.1 - 0.019 15.4 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 AAG08422.1 - 0.022 14.9 0.3 0.07 13.2 0.3 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 AAG08422.1 - 0.028 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 AAG08422.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 AAG08422.1 - 0.049 13.6 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SLATT_1 PF18181.1 AAG08422.1 - 0.68 9.9 2.8 0.53 10.2 0.7 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DHQ_synthase PF01761.20 AAG08423.1 - 4.1e-108 360.5 0.0 5.1e-108 360.2 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AAG08423.1 - 1.3e-14 54.5 0.2 2.6e-13 50.2 0.2 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AAG08423.1 - 3.8e-07 29.2 0.3 6.4e-07 28.5 0.3 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SKI PF01202.22 AAG08424.1 - 1.7e-55 187.4 0.0 2e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 AAG08424.1 - 1.8e-05 25.3 0.1 5.5e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AAG08424.1 - 1.9e-05 24.5 0.2 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 2 Cytidylate kinase AAA_33 PF13671.6 AAG08424.1 - 0.0003 20.9 0.0 0.00073 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AAG08424.1 - 0.00035 20.7 0.2 0.039 14.1 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA PF00004.29 AAG08424.1 - 0.0049 17.3 0.0 0.0069 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AAG08424.1 - 0.0083 16.6 0.1 0.0092 16.5 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAG08424.1 - 0.019 15.3 0.2 0.052 13.9 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAG08424.1 - 0.024 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAG08424.1 - 0.043 13.5 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAG08424.1 - 0.05 13.5 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain APS_kinase PF01583.20 AAG08424.1 - 0.052 13.4 0.1 0.13 12.1 0.1 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase dNK PF01712.19 AAG08424.1 - 0.054 13.3 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 AAG08424.1 - 0.055 13.5 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 AAG08424.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AAG08424.1 - 0.061 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CHDNT PF08073.12 AAG08424.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain RNA_helicase PF00910.22 AAG08424.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 AAG08424.1 - 0.19 11.5 0.1 0.31 10.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG08424.1 - 0.2 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 AAG08424.1 - 0.21 11.1 0.8 0.82 9.2 0.8 1.9 1 1 0 1 1 1 0 AAA domain Secretin PF00263.21 AAG08425.1 - 1.7e-49 167.7 1.6 4.6e-49 166.3 1.6 1.8 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAG08425.1 - 2.5e-15 56.6 2.0 3e-15 56.4 0.3 2.2 2 0 0 2 2 2 1 Bacterial type II/III secretion system short domain AMIN PF11741.8 AAG08425.1 - 9.2e-11 41.7 6.0 5.2e-07 29.7 0.2 3.3 3 0 0 3 3 3 2 AMIN domain STN PF07660.14 AAG08425.1 - 3.1e-09 36.5 1.3 1.7e-08 34.1 0.2 2.7 1 1 1 2 2 2 1 Secretin and TonB N terminus short domain PilP PF04351.13 AAG08426.1 - 2e-49 167.4 0.0 2.2e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Pilus assembly protein, PilP PilO PF04350.13 AAG08427.1 - 1.8e-56 190.4 0.1 2.4e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 Pilus assembly protein, PilO HemX PF04375.14 AAG08427.1 - 0.014 14.7 0.7 0.019 14.2 0.7 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase OATP PF03137.20 AAG08427.1 - 0.17 10.1 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PilN PF05137.13 AAG08428.1 - 7.6e-20 70.8 0.2 1.2e-19 70.2 0.2 1.3 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) RPA_interact_N PF14766.6 AAG08428.1 - 0.11 12.2 4.4 1.8 8.3 0.7 2.5 2 0 0 2 2 2 0 Replication protein A interacting N-terminal PilM_2 PF11104.8 AAG08429.1 - 2.9e-139 463.9 0.6 3.2e-139 463.7 0.6 1.0 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; FtsA PF14450.6 AAG08429.1 - 1.6e-12 47.7 0.1 1.6e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 AAG08429.1 - 4.8e-06 25.6 1.7 0.0073 15.2 0.0 2.7 3 1 0 3 3 3 2 MreB/Mbl protein DDR PF08841.10 AAG08429.1 - 8.2e-06 25.0 4.8 0.008 15.2 0.0 3.1 2 1 1 3 3 3 3 Diol dehydratase reactivase ATPase-like domain Actin PF00022.19 AAG08429.1 - 0.004 15.8 0.7 0.03 12.9 0.1 2.4 2 1 1 3 3 3 1 Actin Transgly PF00912.22 AAG08430.1 - 2.5e-65 219.3 0.0 4.2e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AAG08430.1 - 3.9e-33 115.0 0.0 5.1e-24 85.0 0.0 2.8 2 1 0 2 2 2 2 Penicillin binding protein transpeptidase domain PCB_OB PF17092.5 AAG08430.1 - 2.1e-25 89.7 0.3 3.8e-25 88.8 0.3 1.5 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain malic PF00390.19 AAG08431.1 - 3.1e-28 98.8 0.2 1.9e-25 89.7 0.2 2.4 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 AAG08431.1 - 9e-27 94.0 0.2 2.6e-26 92.5 0.2 1.7 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 AAG08431.1 - 0.00028 20.3 0.2 0.00068 19.0 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 AAG08431.1 - 0.0082 15.9 0.3 0.014 15.1 0.0 1.5 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.21 AAG08431.1 - 0.12 11.8 0.4 0.24 10.7 0.4 1.4 1 0 0 1 1 1 0 ThiF family DUF5440 PF17509.2 AAG08431.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5440) Peptidase_M48 PF01435.18 AAG08432.1 - 1.6e-42 145.5 0.1 3.3e-42 144.5 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M48 DUF2201_N PF13203.6 AAG08432.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain LysM PF01476.20 AAG08432.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 LysM domain SNase PF00565.17 AAG08433.1 - 1e-16 61.4 0.0 1.7e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ribosomal_L31 PF01197.18 AAG08434.1 - 9.5e-31 105.8 0.1 1.1e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 PriA_3primeBD PF17764.1 AAG08435.1 - 5.6e-26 90.3 0.0 1.3e-25 89.1 0.0 1.7 2 0 0 2 2 1 1 3′ DNA-binding domain (3′BD) PriA_C PF18074.1 AAG08435.1 - 5.5e-23 81.6 0.0 1.5e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 Primosomal protein N C-terminal domain DEAD PF00270.29 AAG08435.1 - 1.1e-14 54.5 0.0 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG08435.1 - 1.4e-12 47.9 0.0 4.4e-06 27.0 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 AAG08435.1 - 2e-12 47.4 0.0 3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PriA_CRR PF18319.1 AAG08435.1 - 6.6e-11 42.0 9.3 6.6e-11 42.0 9.3 2.9 3 0 0 3 3 2 1 PriA DNA helicase Cys-rich region (CRR) domain AAA_30 PF13604.6 AAG08435.1 - 0.00058 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SH3_16 PF18348.1 AAG08435.1 - 0.001 18.8 0.0 0.9 9.4 0.1 2.9 2 0 0 2 2 2 2 Bacterial dipeptidyl-peptidase Sh3 domain zinc-ribbons_6 PF07191.12 AAG08435.1 - 0.0021 18.0 5.4 0.0047 16.9 5.4 1.5 1 0 0 1 1 1 1 zinc-ribbons AAA_16 PF13191.6 AAG08435.1 - 0.0065 16.9 3.2 0.01 16.2 0.6 2.7 3 0 0 3 3 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 AAG08435.1 - 0.042 12.7 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 AAG08435.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain HypA PF01155.19 AAG08435.1 - 0.11 12.6 6.8 2.6 8.1 7.6 2.5 2 1 0 2 2 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PIF1 PF05970.14 AAG08435.1 - 0.23 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase zf-TFIIB PF13453.6 AAG08435.1 - 1.1 8.7 7.1 1.2 8.6 2.8 2.8 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-HYPF PF07503.12 AAG08435.1 - 1.9 8.4 8.3 5.4 6.9 0.2 3.4 3 0 0 3 3 3 0 HypF finger tRNA-synt_1d PF00750.19 AAG08436.1 - 1.6e-125 418.7 0.0 1.9e-125 418.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 AAG08436.1 - 1e-31 109.6 0.0 2e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 AAG08436.1 - 7.8e-26 90.5 0.0 9.8e-25 87.0 0.0 2.7 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain HemN_C PF06969.16 AAG08436.1 - 0.026 14.6 0.2 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 HemN C-terminal domain SPOR PF05036.13 AAG08437.1 - 9.8e-17 61.1 1.4 3.5e-16 59.3 0.2 2.3 2 0 0 2 2 2 1 Sporulation related domain SPATA3 PF15662.5 AAG08437.1 - 1.1 9.8 5.9 2.1 9.0 5.9 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Proteasome PF00227.26 AAG08438.1 - 3.2e-21 75.7 0.2 5.8e-21 74.8 0.2 1.4 1 1 0 1 1 1 1 Proteasome subunit AAA_2 PF07724.14 AAG08439.1 - 1.3e-48 165.3 0.5 1.1e-39 136.3 0.2 2.5 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AAG08439.1 - 5.3e-17 62.5 0.1 2.3e-07 31.3 0.0 2.8 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAG08439.1 - 6.4e-08 33.0 0.1 4e-05 23.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 AAG08439.1 - 9.1e-08 32.2 0.1 1.9e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAG08439.1 - 1.5e-06 27.5 0.0 0.00038 19.6 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 AAG08439.1 - 1.7e-05 25.3 4.4 6.1e-05 23.5 1.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AAG08439.1 - 4.8e-05 22.8 0.7 0.0039 16.6 0.2 3.5 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAG08439.1 - 5.2e-05 23.1 0.4 0.044 13.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain ClpB_D2-small PF10431.9 AAG08439.1 - 6e-05 23.0 1.1 0.0005 20.1 0.1 2.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_18 PF13238.6 AAG08439.1 - 0.00025 21.6 0.1 0.0029 18.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 AAG08439.1 - 0.0012 18.6 0.0 0.021 14.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 AAG08439.1 - 0.0017 18.7 0.9 0.021 15.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 AAG08439.1 - 0.0031 17.0 0.4 0.016 14.6 0.0 2.2 2 1 0 2 2 2 1 Bacterial TniB protein NTPase_1 PF03266.15 AAG08439.1 - 0.0059 16.5 0.1 0.77 9.7 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 AAG08439.1 - 0.006 16.8 0.0 0.021 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAG08439.1 - 0.0075 16.0 0.3 0.039 13.7 0.0 2.2 2 1 0 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 AAG08439.1 - 0.009 15.9 0.2 2 8.3 0.0 3.2 2 1 1 3 3 3 1 NACHT domain ABC_tran PF00005.27 AAG08439.1 - 0.028 14.9 0.0 0.069 13.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 AAG08439.1 - 0.047 13.7 0.3 0.24 11.4 0.0 2.2 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 AAG08439.1 - 0.048 13.7 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 AAG08439.1 - 0.05 13.3 0.1 0.13 12.0 0.0 1.8 2 1 0 2 2 1 0 AAA domain AAA_7 PF12775.7 AAG08439.1 - 0.062 12.8 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region SRP54 PF00448.22 AAG08439.1 - 0.074 12.7 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 AAG08439.1 - 0.088 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.18 AAG08439.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DEAD PF00270.29 AAG08439.1 - 0.12 12.1 0.7 0.79 9.5 0.7 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 AAG08439.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 AAG08439.1 - 0.6 10.4 2.0 3.1 8.1 2.0 2.2 1 1 0 1 1 1 0 AAA domain DUF971 PF06155.12 AAG08440.1 - 9.8e-24 83.8 0.0 1.2e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF971) PhaC_N PF07167.13 AAG08441.1 - 1.2e-65 220.3 0.0 2.4e-65 219.4 0.0 1.5 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.20 AAG08441.1 - 3.6e-22 79.3 0.0 6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 AAG08442.1 - 3e-29 102.4 0.0 1.7e-28 100.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG08442.1 - 1.2e-13 52.2 4.6 1.5e-13 51.9 4.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG08442.1 - 2.4e-10 40.1 0.0 4.5e-10 39.2 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAG08442.1 - 0.00031 19.5 0.0 0.00043 19.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 AAG08442.1 - 0.0035 17.4 0.0 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein PhaC_N PF07167.13 AAG08443.1 - 1.5e-65 220.0 0.0 2.3e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.20 AAG08443.1 - 5e-14 52.6 0.1 6.8e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold TetR PF13972.6 AAG08444.1 - 1.6e-31 108.9 0.2 2.2e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 Bacterial transcriptional repressor TetR_N PF00440.23 AAG08444.1 - 1.1e-09 37.9 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 AAG08444.1 - 0.0065 16.5 0.3 0.12 12.4 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.6 AAG08444.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 AAG08444.1 - 0.098 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_5 PF01022.20 AAG08444.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Phasin PF05597.11 AAG08445.1 - 7.2e-46 155.3 5.2 1.2e-45 154.5 5.2 1.3 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 AAG08445.1 - 0.00058 19.8 0.5 0.0012 18.8 0.5 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain AIP3 PF03915.13 AAG08445.1 - 0.055 12.6 0.7 0.081 12.0 0.7 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Cep57_CLD_2 PF14197.6 AAG08445.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ACT_5 PF13710.6 AAG08445.1 - 0.14 12.0 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 ACT domain DUF775 PF05603.12 AAG08445.1 - 1 8.9 7.8 1.3 8.5 6.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Phasin PF05597.11 AAG08446.1 - 1.1e-46 158.0 0.7 1.2e-46 157.8 0.7 1.0 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 AAG08446.1 - 0.013 15.4 0.2 0.019 14.9 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 AAG08446.1 - 0.019 15.0 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Transcrip_act PF04949.13 AAG08446.1 - 0.037 13.9 0.2 0.062 13.2 0.2 1.4 1 1 0 1 1 1 0 Transcriptional activator PhoU PF01895.19 AAG08446.1 - 0.076 13.5 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 PhoU domain Phage_holin_7_1 PF16081.5 AAG08446.1 - 0.077 13.2 0.3 0.11 12.7 0.3 1.2 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MT0933_antitox PF14013.6 AAG08446.1 - 0.093 13.0 1.7 2 8.8 0.3 2.4 2 0 0 2 2 2 0 MT0933-like antitoxin protein NPV_P10 PF05531.12 AAG08446.1 - 0.096 13.2 1.4 2.2 8.8 0.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF883 PF05957.13 AAG08446.1 - 0.26 11.9 2.2 0.37 11.4 0.1 2.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PHA_gran_rgn PF09650.10 AAG08447.1 - 5e-35 119.6 0.2 5.5e-35 119.5 0.2 1.0 1 0 0 1 1 1 1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) FeS_assembly_P PF01883.19 AAG08447.1 - 0.029 14.5 0.2 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein E3_binding PF02817.17 AAG08447.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 e3 binding domain zf-C3HC PF07967.13 AAG08447.1 - 0.16 12.0 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 C3HC zinc finger-like Ubie_methyltran PF01209.18 AAG08448.1 - 5.2e-99 330.3 0.0 6.3e-99 330.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AAG08448.1 - 3.9e-24 85.2 0.0 7.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08448.1 - 3.3e-22 78.9 0.0 4.5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08448.1 - 1.5e-20 73.6 0.0 2.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG08448.1 - 3.8e-16 59.4 0.0 5.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08448.1 - 3.9e-12 46.8 0.0 6.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAG08448.1 - 7.1e-08 32.5 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 AAG08448.1 - 4.4e-05 23.3 0.0 9.3e-05 22.2 0.0 1.5 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit MetW PF07021.12 AAG08448.1 - 0.00022 20.9 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.18 AAG08448.1 - 0.0028 17.3 0.0 0.0087 15.8 0.0 1.8 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 AAG08448.1 - 0.0032 16.6 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 AAG08448.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltr_RsmB-F PF01189.17 AAG08448.1 - 0.22 11.2 0.0 0.84 9.2 0.0 1.9 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F SCP2 PF02036.17 AAG08449.1 - 3.8e-12 46.6 0.0 6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 AAG08449.1 - 0.013 15.8 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal MDMPI_C PF07398.11 AAG08449.1 - 0.032 15.1 0.5 0.074 13.9 0.5 1.8 1 0 0 1 1 1 0 MDMPI C-terminal domain ABC1 PF03109.16 AAG08450.1 - 9e-37 125.9 0.1 1.9e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 ABC1 family PRA-CH PF01502.18 AAG08451.1 - 1.3e-33 114.7 0.1 1.7e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase SRF-TF PF00319.18 AAG08451.1 - 0.094 12.2 0.1 0.27 10.8 0.0 1.7 1 1 1 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Sortilin-Vps10 PF15902.5 AAG08451.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, PRA-PH PF01503.17 AAG08452.1 - 9e-18 64.5 0.1 1.1e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MttA_Hcf106 PF02416.16 AAG08453.1 - 2.9e-14 52.1 0.0 3.1e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family tRNA_anti-like PF12869.7 AAG08453.1 - 0.0068 16.0 0.0 0.0087 15.7 0.0 1.1 1 0 0 1 1 1 1 tRNA_anti-like MttA_Hcf106 PF02416.16 AAG08454.1 - 3.7e-08 32.6 0.1 4.6e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family TatC PF00902.18 AAG08455.1 - 7.2e-65 218.7 24.0 8.5e-65 218.4 24.0 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF423 PF04241.15 AAG08455.1 - 0.86 9.8 9.5 0.96 9.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF423) Methyltrans_RNA PF04452.14 AAG08456.1 - 7.7e-42 143.2 0.0 8.8e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase MCPsignal PF00015.21 AAG08457.1 - 1.6e-45 155.0 24.3 1.6e-45 155.0 24.3 4.4 3 2 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HBM PF16591.5 AAG08457.1 - 1.5e-41 142.5 27.1 1.5e-41 142.5 27.1 3.3 3 0 0 3 3 3 1 Helical bimodular sensor domain HAMP PF00672.25 AAG08457.1 - 1.6e-09 38.0 2.5 1.6e-09 38.0 2.5 4.8 5 0 0 5 5 5 2 HAMP domain Phageshock_PspD PF09584.10 AAG08457.1 - 0.0079 16.2 1.3 0.029 14.4 0.4 2.3 2 0 0 2 2 2 1 Phage shock protein PspD (Phageshock_PspD) Fib_alpha PF08702.10 AAG08457.1 - 0.042 14.0 14.4 0.2 11.8 3.6 4.6 3 3 2 5 5 5 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 AAG08457.1 - 0.2 12.0 0.1 0.2 12.0 0.1 5.3 4 3 2 6 6 6 0 Uncharacterized conserved protein DUF1652 PF07865.11 AAG08457.1 - 0.5 10.2 3.3 0.79 9.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) DUF948 PF06103.11 AAG08457.1 - 1.5 9.1 35.2 0.31 11.3 6.0 6.7 4 3 2 6 6 6 0 Bacterial protein of unknown function (DUF948) UPF0158 PF03682.13 AAG08458.1 - 7.7e-57 191.7 0.0 8.4e-57 191.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0158) ABC_tran PF00005.27 AAG08459.1 - 7.1e-38 130.2 0.0 9e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG08459.1 - 4e-11 43.3 0.0 5.7e-05 23.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG08459.1 - 2.6e-06 27.0 0.0 0.0043 16.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG08459.1 - 8.6e-05 23.0 0.4 0.00012 22.5 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG08459.1 - 0.00019 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAG08459.1 - 0.00069 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AAG08459.1 - 0.0027 17.9 0.0 0.026 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAG08459.1 - 0.003 17.8 0.0 0.0051 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AAG08459.1 - 0.0042 16.8 0.0 0.0087 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 AAG08459.1 - 0.0064 16.4 0.0 0.0083 16.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain IIGP PF05049.13 AAG08459.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 AAG08459.1 - 0.022 15.3 0.0 0.038 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG08459.1 - 0.032 13.9 0.0 0.066 12.9 0.0 1.5 1 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 AAG08459.1 - 0.033 13.9 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAG08459.1 - 0.039 14.4 0.0 0.072 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAG08459.1 - 0.059 12.2 0.0 5.1 5.8 0.0 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 AAG08459.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain VirE PF05272.11 AAG08459.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E FtsK_SpoIIIE PF01580.18 AAG08459.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family SbcCD_C PF13558.6 AAG08459.1 - 0.084 13.1 0.2 0.91 9.8 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 AAG08459.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA12 PF10443.9 AAG08459.1 - 0.12 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein NACHT PF05729.12 AAG08459.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 AAG08459.1 - 0.14 10.8 0.0 2.5 6.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AAG08459.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 KaiC PRK PF00485.18 AAG08459.1 - 0.17 11.6 0.1 3.5 7.3 0.1 2.2 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family BPD_transp_1 PF00528.22 AAG08460.1 - 3.6e-24 85.5 4.9 3.6e-24 85.5 4.9 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component TOBE_2 PF08402.10 AAG08460.1 - 0.019 15.1 0.3 0.051 13.7 0.3 1.6 1 0 0 1 1 1 0 TOBE domain TOBE PF03459.17 AAG08460.1 - 0.041 14.2 1.0 1 9.7 0.5 2.5 2 0 0 2 2 2 0 TOBE domain Peptidase_M23 PF01551.22 AAG08460.1 - 0.061 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M23 HCV_NS4a PF01006.20 AAG08460.1 - 0.11 12.3 0.1 5.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a PepSY_TM PF03929.16 AAG08460.1 - 0.13 12.0 2.9 0.11 12.2 1.3 1.7 2 0 0 2 2 2 0 PepSY-associated TM region SBP_bac_3 PF00497.20 AAG08461.1 - 3.9e-57 193.3 0.0 4.6e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG08461.1 - 8.6e-10 38.8 0.0 2.6e-08 34.0 0.0 2.5 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAG08461.1 - 0.0026 17.7 0.4 1.1 9.1 0.0 2.1 1 1 0 2 2 2 2 NMT1/THI5 like DUF761 PF05553.11 AAG08461.1 - 1.1 8.9 3.2 13 5.4 0.1 2.4 2 0 0 2 2 2 0 Cotton fibre expressed protein Glycos_transf_2 PF00535.26 AAG08462.1 - 1.1e-23 83.8 0.0 1.7e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAG08462.1 - 1.9e-11 44.2 11.2 1.9e-11 44.2 11.2 3.4 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAG08462.1 - 4.2e-07 29.6 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 AAG08462.1 - 2.3e-05 24.4 0.1 8.3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 MdoG PF04349.12 AAG08463.1 - 7.3e-200 664.9 0.1 8.3e-200 664.7 0.1 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG Tyr_Deacylase PF02580.16 AAG08464.1 - 9.9e-52 175.3 0.0 1.1e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Abhydrolase_1 PF00561.20 AAG08465.1 - 8.8e-38 130.4 0.1 1.5e-37 129.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAG08465.1 - 5e-14 53.4 5.5 6.8e-14 53.0 5.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG08465.1 - 1.8e-13 50.3 0.0 6.1e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 AAG08465.1 - 0.0038 17.3 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 AAG08465.1 - 0.0066 15.2 0.0 0.009 14.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 AAG08465.1 - 0.019 13.8 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S15 PF02129.18 AAG08465.1 - 0.06 12.9 0.1 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.14 AAG08465.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase NUDIX PF00293.28 AAG08466.1 - 1.8e-11 44.2 0.2 2.5e-11 43.8 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain SBP_bac_3 PF00497.20 AAG08467.1 - 2.3e-50 171.1 0.0 2.7e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAG08467.1 - 1.7e-05 24.6 0.1 2.6e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAG08467.1 - 0.00054 20.0 0.1 0.0012 18.8 0.1 1.5 1 1 0 1 1 1 1 NMT1/THI5 like Ribonuc_L-PSP PF01042.21 AAG08468.1 - 1.8e-25 89.3 0.0 2e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DAO PF01266.24 AAG08469.1 - 3.7e-65 220.8 5.6 4.3e-65 220.6 5.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAG08469.1 - 1.9e-09 37.2 0.1 0.00035 19.9 0.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAG08469.1 - 1.3e-08 34.6 0.4 0.0005 19.5 0.3 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAG08469.1 - 1.6e-08 34.6 0.7 3.9e-08 33.4 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAG08469.1 - 4.6e-07 29.3 1.4 6.3e-05 22.2 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 AAG08469.1 - 1.1e-05 25.5 1.6 0.08 12.9 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 AAG08469.1 - 0.00025 20.4 0.2 0.00025 20.4 0.2 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AAG08469.1 - 0.00094 19.7 1.3 0.0021 18.6 0.7 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG08469.1 - 0.001 18.7 0.2 0.0015 18.1 0.2 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AAG08469.1 - 0.002 18.0 0.3 0.0032 17.4 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AAG08469.1 - 0.0078 15.9 0.3 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 AAG08469.1 - 0.01 15.2 0.2 0.014 14.7 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AAG08469.1 - 0.011 14.9 0.2 0.04 13.0 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 AAG08469.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 AAG08469.1 - 0.012 15.0 1.5 0.018 14.4 1.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAG08469.1 - 0.015 14.6 0.1 0.2 10.9 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG08469.1 - 0.016 14.5 1.2 0.017 14.4 0.2 1.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 AAG08469.1 - 0.018 13.8 0.7 0.11 11.1 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Rossmann-like PF10727.9 AAG08469.1 - 0.21 11.5 2.0 0.35 10.7 0.2 2.1 2 0 0 2 2 2 0 Rossmann-like domain Trp_halogenase PF04820.14 AAG08469.1 - 0.25 10.1 0.3 0.44 9.3 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FMO-like PF00743.19 AAG08469.1 - 0.31 9.4 0.1 0.42 9.0 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like LysR_substrate PF03466.20 AAG08470.1 - 3e-34 118.2 11.7 5e-34 117.5 11.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08470.1 - 1.2e-17 63.5 0.7 3.2e-17 62.2 0.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG08470.1 - 0.013 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain YdaS_antitoxin PF15943.5 AAG08470.1 - 0.015 15.1 0.1 0.049 13.5 0.1 1.9 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 AAG08470.1 - 0.047 13.5 1.1 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain MarR_2 PF12802.7 AAG08470.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.5 3 0 0 3 3 3 0 MarR family P22_Cro PF14549.6 AAG08470.1 - 0.2 11.5 0.6 0.52 10.2 0.2 1.8 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro Sel1 PF08238.12 AAG08471.1 - 6.5e-06 26.6 5.1 0.0041 17.8 0.0 5.0 4 2 0 4 4 4 1 Sel1 repeat TPR_1 PF00515.28 AAG08471.1 - 1.5 8.8 5.9 4.4 7.3 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 AAG08472.1 - 4.4e-07 30.4 12.8 5.3e-05 23.8 0.0 5.7 6 1 0 6 6 6 2 Sel1 repeat TPR_7 PF13176.6 AAG08472.1 - 0.0024 17.8 0.4 2.8 8.2 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAG08472.1 - 0.0033 17.9 0.0 1.8 9.4 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAG08472.1 - 0.094 12.9 5.6 11 6.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAG08472.1 - 0.48 10.9 2.4 14 6.3 0.0 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAG08472.1 - 2.4 8.1 13.5 2.4 8.1 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 AAG08473.1 - 6.6e-08 33.0 17.6 0.00029 21.4 0.1 5.3 6 0 0 6 6 6 2 Sel1 repeat TPR_6 PF13174.6 AAG08473.1 - 0.29 11.8 4.8 0.98 10.2 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAG08473.1 - 0.57 10.3 3.7 2.1 8.6 0.0 3.5 5 1 0 5 5 5 0 Tetratricopeptide repeat PLDc_2 PF13091.6 AAG08474.1 - 1.6e-10 41.0 0.0 0.0001 22.2 0.0 4.3 4 0 0 4 4 4 3 PLD-like domain PLDc PF00614.22 AAG08474.1 - 4.8e-06 26.5 1.8 0.021 15.0 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif ABC_tran_CTD PF16326.5 AAG08474.1 - 0.00096 19.4 0.8 0.91 9.8 0.3 3.0 2 0 0 2 2 2 2 ABC transporter C-terminal domain DUF3375 PF11855.8 AAG08474.1 - 0.06 12.3 3.6 0.36 9.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Phage_GPD PF05954.11 AAG08475.1 - 4.3e-79 266.0 0.6 4.3e-79 266.0 0.6 1.6 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 AAG08475.1 - 0.0039 17.1 0.0 0.024 14.5 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) Phage_base_V PF04717.12 AAG08475.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector FGase PF05013.12 AAG08476.1 - 7.7e-71 238.7 0.3 9.2e-71 238.5 0.3 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase zf-UBP PF02148.19 AAG08476.1 - 0.082 13.3 0.2 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Amidohydro_1 PF01979.20 AAG08477.1 - 4.9e-21 75.4 0.3 3.2e-20 72.8 0.3 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG08477.1 - 2.6e-19 70.0 4.7 2.3e-14 53.8 1.0 2.3 1 1 1 2 2 2 2 Amidohydrolase family Lyase_aromatic PF00221.19 AAG08478.1 - 2.7e-160 534.1 12.9 3.1e-160 533.9 12.9 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Borrelia_P83 PF05262.11 AAG08478.1 - 0.089 11.3 0.0 0.18 10.3 0.0 1.4 2 0 0 2 2 2 0 Borrelia P83/100 protein ABC_tran PF00005.27 AAG08479.1 - 3.7e-32 111.7 0.0 5.6e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 AAG08479.1 - 2.1e-05 24.8 0.0 4.8e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG08479.1 - 3.3e-05 24.3 0.1 6.9e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 AAG08479.1 - 0.00025 20.0 0.1 0.028 13.2 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 AAG08479.1 - 0.0023 17.6 0.1 0.0044 16.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 AAG08479.1 - 0.0043 17.0 0.2 0.029 14.3 0.2 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_21 PF13304.6 AAG08479.1 - 0.0075 16.1 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAG08479.1 - 0.0076 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 AAG08479.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAG08479.1 - 0.024 14.7 0.0 0.064 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAG08479.1 - 0.027 14.2 0.0 0.14 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 AAG08479.1 - 0.029 13.8 0.1 0.52 9.7 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF4190 PF13828.6 AAG08479.1 - 0.035 13.9 0.1 0.082 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) AAA_5 PF07728.14 AAG08479.1 - 0.078 13.0 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 AAG08479.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 AAG08479.1 - 0.089 12.5 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AAG08479.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 AAG08479.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG08479.1 - 0.16 12.2 0.5 0.38 11.0 0.5 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 AAG08479.1 - 0.17 12.4 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAG08480.1 - 2.1e-26 92.8 12.2 2.1e-26 92.8 12.2 3.0 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component OpuAC PF04069.12 AAG08481.1 - 2.2e-65 220.8 0.0 2.6e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system AA_permease PF00324.21 AAG08482.1 - 3.4e-102 342.5 48.3 4.1e-102 342.2 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG08482.1 - 1.4e-44 152.6 53.2 1.6e-44 152.4 53.2 1.0 1 0 0 1 1 1 1 Amino acid permease Lyase_aromatic PF00221.19 AAG08483.1 - 1.9e-184 613.7 10.3 2.2e-184 613.5 10.3 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase COE1_HLH PF16423.5 AAG08483.1 - 0.043 13.5 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain Transp_cyt_pur PF02133.15 AAG08484.1 - 1.1e-45 156.2 40.0 2.5e-45 155.1 40.0 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Urocanase_C PF17392.2 AAG08485.1 - 2.7e-92 307.6 0.1 4.5e-92 306.9 0.1 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 AAG08485.1 - 2.1e-88 295.5 0.0 2.9e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 AAG08485.1 - 4.3e-63 210.7 0.0 7.8e-63 209.8 0.0 1.4 1 0 0 1 1 1 1 Urocanase N-terminal domain Phosphonate-bd PF12974.7 AAG08486.1 - 2.3e-15 56.9 0.0 2.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein FA_desaturase PF00487.24 AAG08487.1 - 9.5e-33 114.1 24.3 9.5e-33 114.1 24.3 1.9 1 1 0 2 2 2 1 Fatty acid desaturase OpuAC PF04069.12 AAG08488.1 - 1.1e-60 205.4 0.0 1.3e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system HutD PF05962.11 AAG08489.1 - 1.5e-54 184.8 0.0 1.7e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 HutD UTRA PF07702.13 AAG08490.1 - 1.5e-36 125.3 1.0 2e-36 124.9 1.0 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAG08490.1 - 4.9e-20 70.9 0.0 1e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 AAG08490.1 - 0.00082 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR PF01047.22 AAG08490.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAG08490.1 - 0.0039 17.1 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAG08490.1 - 0.0081 15.7 0.0 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAG08490.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 0 MarR family RP-C PF03428.13 AAG08490.1 - 0.031 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_11 PF08279.12 AAG08490.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 AAG08490.1 - 0.077 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Amidohydro_1 PF01979.20 AAG08491.1 - 1.7e-36 126.3 0.0 2e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAG08491.1 - 3.6e-10 39.9 2.7 3.6e-10 39.9 2.7 2.3 1 1 0 2 2 2 1 Amidohydrolase family Lipocalin_2 PF08212.12 AAG08492.1 - 1.8e-61 206.3 0.5 2.1e-61 206.1 0.5 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 AAG08492.1 - 2.2e-05 24.7 0.0 2.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF2931 PF11153.8 AAG08492.1 - 0.06 13.0 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) SmpA_OmlA PF04355.13 AAG08493.1 - 5.2e-06 26.2 0.0 7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 SmpA / OmlA family DUF3862 PF12978.7 AAG08493.1 - 0.0005 19.9 0.0 0.0036 17.2 0.0 1.8 1 1 1 2 2 2 1 Domain of Unknown Function with PDB structure (DUF3862) DUF4995 PF16386.5 AAG08493.1 - 0.029 14.4 1.6 0.094 12.7 1.5 1.8 1 1 1 2 2 2 0 Domain of unknown function ABC_membrane PF00664.23 AAG08493.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF3192 PF11399.8 AAG08493.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) RPAP1_N PF08621.10 AAG08493.1 - 0.19 11.5 0.1 0.27 11.0 0.1 1.2 1 0 0 1 1 1 0 RPAP1-like, N-terminal DUF924 PF06041.11 AAG08494.1 - 1.5e-57 194.6 0.0 1.7e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF732 PF05305.14 AAG08494.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF732) FBPase PF00316.20 AAG08495.1 - 1.2e-60 204.2 0.0 1.6e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Glyoxalase PF00903.25 AAG08496.1 - 1.2e-23 83.7 0.0 1.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAG08496.1 - 1.7e-08 34.7 0.0 7.4e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAG08496.1 - 3.6e-06 27.7 0.0 4.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AAG08496.1 - 0.0036 17.2 0.0 0.21 11.5 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AAG08496.1 - 0.093 12.8 0.0 0.35 11.0 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Autotransporter PF03797.19 AAG08497.1 - 1.2e-47 162.8 19.6 1.2e-47 162.8 19.6 1.6 2 0 0 2 2 2 1 Autotransporter beta-domain Lipase_GDSL PF00657.22 AAG08497.1 - 5.5e-14 52.6 0.0 8.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OMP_b-brl PF13505.6 AAG08497.1 - 3.7e-06 27.2 23.1 3e-05 24.2 5.2 3.9 2 2 1 4 4 4 3 Outer membrane protein beta-barrel domain Lipase_GDSL_2 PF13472.6 AAG08497.1 - 2.1e-05 25.0 5.6 0.00022 21.6 5.6 2.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OmpA_membrane PF01389.17 AAG08497.1 - 0.035 13.8 3.0 0.076 12.7 2.5 1.8 1 1 1 2 2 2 0 OmpA-like transmembrane domain DUF3575 PF12099.8 AAG08497.1 - 0.36 10.1 7.3 0.13 11.5 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3575) DUF3999 PF13163.6 AAG08498.1 - 1.2e-149 499.2 12.3 1.4e-149 499.0 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3999) F5_F8_type_C PF00754.25 AAG08498.1 - 0.0086 16.2 0.0 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain DUF2339 PF10101.9 AAG08499.1 - 3e-151 505.3 190.7 6.4e-105 352.2 66.2 4.1 1 1 2 4 4 4 4 Predicted membrane protein (DUF2339) Methyltransf_25 PF13649.6 AAG08500.1 - 5.1e-12 46.3 0.0 1e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08500.1 - 4.6e-08 33.6 0.0 1.5e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 AAG08500.1 - 0.0014 18.1 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 AAG08500.1 - 0.0051 16.7 0.0 0.0082 16.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08500.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 AAG08500.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MerR_1 PF13411.6 AAG08501.1 - 1.6e-13 50.5 0.0 3.2e-13 49.5 0.0 1.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AAG08501.1 - 4.2e-12 45.6 2.0 4.5e-12 45.5 0.4 2.0 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 AAG08501.1 - 1.1e-09 38.7 5.1 1.1e-09 38.7 5.1 1.6 2 0 0 2 2 2 1 MerR, DNA binding HTH_17 PF12728.7 AAG08501.1 - 0.0042 17.2 1.5 0.029 14.6 0.1 2.8 4 0 0 4 4 4 1 Helix-turn-helix domain AbiEi_4 PF13338.6 AAG08501.1 - 0.0073 16.4 5.6 0.06 13.5 0.1 3.2 3 1 1 4 4 4 2 Transcriptional regulator, AbiEi antitoxin HTH_3 PF01381.22 AAG08501.1 - 0.12 12.4 0.5 0.75 9.9 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix GTP_EFTU PF00009.27 AAG08502.1 - 5.8e-58 195.6 0.1 9.5e-58 194.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AAG08502.1 - 5e-22 77.7 0.1 1.6e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAG08502.1 - 2.2e-10 40.8 1.1 8.7e-10 38.9 1.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAG08502.1 - 1.4e-07 31.6 0.2 3e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 AAG08502.1 - 0.00082 18.7 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Septin EFG_II PF14492.6 AAG08502.1 - 0.0037 17.3 0.0 0.0092 16.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.23 AAG08502.1 - 0.0073 16.4 0.0 0.035 14.2 0.0 2.0 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 AAG08502.1 - 0.01 15.4 0.0 0.11 12.0 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 AAG08502.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 AAG08502.1 - 0.26 10.7 1.1 0.88 9.0 0.1 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit ThiI PF02568.14 AAG08503.1 - 1.4e-64 217.3 0.0 2e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 AAG08503.1 - 5.3e-22 78.5 0.2 1.7e-21 76.9 0.1 2.0 2 0 0 2 2 2 1 THUMP domain QueC PF06508.13 AAG08503.1 - 1.3e-05 24.8 0.0 0.0002 21.0 0.0 2.3 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AAG08503.1 - 0.002 17.0 0.0 0.0038 16.1 0.0 1.5 1 0 0 1 1 1 1 tRNA methyl transferase Diphthami_syn_2 PF01902.17 AAG08503.1 - 0.0044 16.5 0.3 1.4 8.4 0.0 2.8 1 1 1 2 2 2 2 Diphthamide synthase Rhodanese PF00581.20 AAG08503.1 - 0.018 15.6 0.0 0.058 13.9 0.0 1.9 1 0 0 1 1 1 0 Rhodanese-like domain ADH_N_2 PF16884.5 AAG08503.1 - 0.088 12.7 0.2 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Gln-synt_C PF00120.24 AAG08504.1 - 8.6e-139 462.3 0.0 1e-138 462.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAG08504.1 - 3.3e-30 103.6 0.2 6.3e-30 102.7 0.2 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF1039 PF06287.11 AAG08505.1 - 0.58 10.6 3.9 66 4.0 0.2 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF1039) MS_channel PF00924.18 AAG08506.1 - 4.5e-39 134.1 0.0 8.3e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2171 PF09939.9 AAG08506.1 - 0.21 11.9 0.1 0.41 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) YrhC PF14143.6 AAG08506.1 - 0.25 11.5 2.2 1.5 9.0 2.2 2.4 1 0 0 1 1 1 0 YrhC-like protein ATP_synth_reg PF14960.6 AAG08506.1 - 4.1 7.0 7.9 2.2 7.8 1.5 2.6 2 0 0 2 2 2 0 ATP synthase regulation DUF4124 PF13511.6 AAG08507.1 - 3.8e-15 55.9 2.8 9.5e-15 54.7 2.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4124) BiPBP_C PF06832.12 AAG08507.1 - 0.0026 17.8 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family DUF4124 PF13511.6 AAG08508.1 - 1e-14 54.6 0.6 1e-14 54.6 0.6 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4124) HisKA PF00512.25 AAG08509.1 - 1.1e-15 57.4 0.6 3.9e-15 55.6 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAG08509.1 - 9.3e-15 55.1 0.0 1.7e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAG08509.1 - 1.5e-06 28.2 0.1 5.8e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAG08509.1 - 3.7e-05 23.6 0.1 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AAG08509.1 - 5.3e-05 23.4 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG08509.1 - 0.0037 17.5 0.0 0.0091 16.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 AAG08509.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.9 1 1 0 1 1 1 0 GHKL domain Sigma54_activat PF00158.26 AAG08510.1 - 2.5e-71 238.8 0.0 4.1e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAG08510.1 - 6.2e-29 100.4 0.0 1.5e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAG08510.1 - 2.7e-24 85.8 0.0 1.9e-23 83.1 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG08510.1 - 3.1e-13 49.3 2.4 3.4e-13 49.1 0.3 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAG08510.1 - 5e-08 33.0 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAG08510.1 - 6.2e-05 23.4 0.0 0.00074 19.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAG08510.1 - 0.0011 19.2 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) HsbA PF12296.8 AAG08510.1 - 0.01 16.3 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Mg_chelatase PF01078.21 AAG08510.1 - 0.021 14.2 0.1 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI OKR_DC_1_N PF03709.15 AAG08510.1 - 0.032 14.5 0.0 0.096 13.0 0.0 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_7 PF12775.7 AAG08510.1 - 0.19 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4675 PF15720.5 AAG08511.1 - 2.7 7.7 5.9 1.3 8.8 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4675) SpoU_methylase PF00588.19 AAG08512.1 - 1.5e-31 109.5 0.0 1.6e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Malate_DH PF12434.8 AAG08512.1 - 0.047 13.7 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 Malate dehydrogenase enzyme SecB PF02556.14 AAG08513.1 - 2.5e-54 183.0 0.0 2.9e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB Glutaredoxin PF00462.24 AAG08514.1 - 6.7e-22 77.5 0.0 8e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AAG08514.1 - 0.00042 20.7 0.0 0.00047 20.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAG08514.1 - 0.0014 18.8 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 AAG08514.1 - 0.0057 17.1 0.1 0.024 15.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 AAG08514.1 - 0.022 14.5 0.2 0.027 14.2 0.2 1.3 1 1 0 1 1 1 0 Redoxin DUF836 PF05768.14 AAG08514.1 - 0.077 13.4 0.0 0.092 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF953 PF06110.11 AAG08514.1 - 0.092 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 AAG08514.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Rhodanese PF00581.20 AAG08515.1 - 4.2e-11 43.3 0.0 5.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain BatA PF07584.11 AAG08515.1 - 0.037 14.4 0.2 0.05 14.0 0.2 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Metalloenzyme PF01676.18 AAG08516.1 - 5.7e-83 278.1 0.0 6.5e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 AAG08516.1 - 4.5e-80 268.1 0.0 7e-80 267.5 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) PglZ PF08665.12 AAG08516.1 - 0.0009 19.4 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 PglZ domain Phosphodiest PF01663.22 AAG08516.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 AAG08516.1 - 0.056 12.8 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Sulfatase PIG-L PF02585.17 AAG08516.1 - 0.078 13.6 0.1 0.77 10.4 0.0 2.4 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase CPBP PF02517.16 AAG08517.1 - 1.5e-19 70.1 11.8 1.5e-19 70.1 11.8 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Peptidase_M23 PF01551.22 AAG08518.1 - 1.8e-25 89.0 0.1 3.1e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M23 DUF3450 PF11932.8 AAG08518.1 - 0.00046 19.6 8.0 0.00046 19.6 8.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) APG6_N PF17675.1 AAG08518.1 - 0.012 16.1 16.9 0.012 16.1 16.9 3.1 1 1 1 2 2 1 0 Apg6 coiled-coil region Laminin_II PF06009.12 AAG08518.1 - 0.019 15.0 7.2 0.019 15.0 7.2 2.4 2 0 0 2 2 1 0 Laminin Domain II GAS PF13851.6 AAG08518.1 - 0.082 12.2 40.2 0.053 12.9 12.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 AAG08518.1 - 0.1 11.6 23.9 0.36 9.8 9.7 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 AAG08518.1 - 0.13 12.3 17.7 0.91 9.6 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 AAG08518.1 - 0.78 8.3 26.2 0.015 13.9 8.7 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 AAG08518.1 - 0.9 8.4 36.3 0.051 12.5 11.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 AAG08518.1 - 0.95 9.9 44.5 0.69 10.3 12.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.8 AAG08518.1 - 2.9 7.9 36.2 0.17 11.9 9.9 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 AAG08518.1 - 3.6 7.6 10.4 1.2 9.2 1.9 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nsp1_C PF05064.13 AAG08518.1 - 8.4 6.2 19.4 0.64 9.8 2.0 3.2 3 1 0 4 4 3 0 Nsp1-like C-terminal region DUF3584 PF12128.8 AAG08518.1 - 8.9 3.7 40.7 13 3.2 40.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 AAG08518.1 - 9.1 5.4 24.7 0.41 9.8 8.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein Peptidase_S41 PF03572.18 AAG08519.1 - 9.3e-58 194.5 0.1 1.3e-57 193.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 AAG08519.1 - 3e-17 62.2 0.1 7.4e-17 61.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AAG08519.1 - 2.2e-12 47.1 0.3 7.3e-12 45.4 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 AAG08519.1 - 7.5e-11 42.2 0.2 1.6e-10 41.2 0.2 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 AAG08519.1 - 0.0007 19.5 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain TSP_NTD PF17804.1 AAG08519.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Polysacc_deac_2 PF04748.13 AAG08520.1 - 2e-72 242.8 0.1 2.3e-72 242.6 0.1 1.0 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase DUF3107 PF11305.8 AAG08520.1 - 0.021 15.1 0.0 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Sortilin-Vps10 PF15902.5 AAG08521.1 - 0.0031 16.4 0.0 0.17 10.6 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 AAG08521.1 - 0.63 10.3 0.1 0.63 10.3 0.1 3.9 4 0 0 4 4 4 0 BNR/Asp-box repeat BNR_6 PF15899.5 AAG08521.1 - 9.7 6.6 7.9 31 5.0 0.1 3.7 4 0 0 4 4 4 0 BNR-Asp box repeat SBP_bac_3 PF00497.20 AAG08522.1 - 2.8e-19 69.4 0.0 3.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 TctC PF03401.14 AAG08522.1 - 0.13 11.3 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter family receptor SBP_bac_3 PF00497.20 AAG08523.1 - 3.1e-18 66.0 0.0 3.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG08523.1 - 0.0028 17.9 0.0 0.013 15.7 0.0 2.0 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 AAG08524.1 - 1e-20 74.2 0.0 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 His_biosynth PF00977.21 AAG08525.1 - 1.2e-92 309.5 0.5 1.3e-92 309.4 0.5 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 AAG08525.1 - 1.1e-07 31.4 1.4 0.0087 15.4 0.1 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 AAG08525.1 - 4.6e-07 29.5 4.7 0.0021 17.5 1.2 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase DHO_dh PF01180.21 AAG08525.1 - 6.4e-06 25.6 0.1 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Dus PF01207.17 AAG08525.1 - 7.4e-06 25.3 0.3 0.0036 16.5 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 AAG08525.1 - 5.6e-05 22.6 0.3 0.0084 15.5 0.0 2.2 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 AAG08525.1 - 7.9e-05 22.1 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase IMPDH PF00478.25 AAG08525.1 - 0.00058 19.0 1.0 0.26 10.2 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 AAG08525.1 - 0.02 14.1 0.0 0.051 12.7 0.0 1.7 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 AAG08525.1 - 0.047 12.7 1.8 0.11 11.6 0.1 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PE PF00934.20 AAG08525.1 - 0.059 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 PE family DUF561 PF04481.12 AAG08525.1 - 0.066 12.4 0.0 1 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF561) His_biosynth PF00977.21 AAG08526.1 - 1.3e-77 260.4 0.6 1.4e-77 260.2 0.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AAG08526.1 - 3.1e-07 29.8 0.9 0.0034 16.5 0.3 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IMPDH PF00478.25 AAG08526.1 - 7.9e-05 21.8 1.0 0.0071 15.4 0.3 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 AAG08526.1 - 9.2e-05 21.8 0.2 0.022 14.1 0.1 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase PcrB PF01884.17 AAG08526.1 - 0.0012 18.4 0.4 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 PcrB family DHO_dh PF01180.21 AAG08526.1 - 0.0021 17.3 0.4 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 AAG08526.1 - 0.0053 16.2 0.2 1.8 8.0 0.1 2.3 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 AAG08526.1 - 0.01 15.2 2.6 0.057 12.8 0.9 2.0 2 0 0 2 2 2 0 Nitronate monooxygenase Trp_syntA PF00290.20 AAG08526.1 - 0.022 13.6 0.3 0.11 11.4 0.1 1.9 2 0 0 2 2 2 0 Tryptophan synthase alpha chain DUF2760 PF10816.8 AAG08526.1 - 0.097 12.5 0.0 6.1 6.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2760) GATase PF00117.28 AAG08527.1 - 9.8e-19 67.9 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AAG08527.1 - 4.4e-06 26.4 0.0 5.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 AAG08527.1 - 0.015 15.1 0.3 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 IGPD PF00475.18 AAG08528.1 - 3.3e-65 218.8 1.4 4.6e-65 218.3 1.0 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase PanZ PF12568.8 AAG08529.1 - 1.8e-32 111.8 0.0 2.1e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_1 PF00583.25 AAG08529.1 - 1.6e-06 28.4 0.1 1.7e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG08529.1 - 6.1e-06 26.2 0.0 8.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAG08529.1 - 0.013 15.9 0.1 0.017 15.6 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAG08529.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DAO PF01266.24 AAG08530.1 - 3.9e-66 224.0 6.8 4.4e-66 223.9 6.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG08530.1 - 1.4e-07 31.0 10.8 4.5e-07 29.3 10.8 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAG08530.1 - 1.9e-06 28.0 0.6 1.9e-06 28.0 0.6 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAG08530.1 - 1.9e-05 24.1 2.2 0.002 17.4 0.5 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 AAG08530.1 - 5.6e-05 22.5 0.0 0.0016 17.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG08530.1 - 0.00021 20.1 0.8 0.00035 19.4 0.8 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 AAG08530.1 - 0.00079 18.8 1.1 0.031 13.6 0.2 2.1 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.16 AAG08530.1 - 0.00092 18.9 0.7 0.0016 18.1 0.7 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 AAG08530.1 - 0.0023 17.2 0.6 0.0051 16.1 0.5 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG08530.1 - 0.0035 17.8 0.2 0.026 15.1 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG08530.1 - 0.0037 16.7 2.8 0.0059 16.0 2.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG08530.1 - 0.0045 16.3 0.2 0.0085 15.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 AAG08530.1 - 0.046 13.6 0.2 0.073 12.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 AAG08530.1 - 0.072 12.4 1.6 0.11 11.8 1.6 1.3 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.14 AAG08530.1 - 0.096 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 AAG08530.1 - 0.11 11.5 3.3 0.18 10.8 1.6 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 AAG08530.1 - 0.25 10.4 0.9 0.34 9.9 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AsmA PF05170.14 AAG08531.1 - 2.4e-192 641.0 1.6 2.8e-192 640.7 1.6 1.1 1 0 0 1 1 1 1 AsmA family AsmA_2 PF13502.6 AAG08531.1 - 3.4e-23 82.4 12.1 1.2e-22 80.6 1.1 3.9 4 0 0 4 4 4 2 AsmA-like C-terminal region DUF748 PF05359.11 AAG08531.1 - 0.053 13.7 6.6 0.5 10.5 0.1 4.3 2 2 2 4 4 4 0 Domain of Unknown Function (DUF748) NUDIX_4 PF14815.6 AAG08532.1 - 5.9e-22 77.7 0.1 1.2e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 AAG08532.1 - 7.7e-21 74.6 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAG08532.1 - 5e-09 35.6 0.0 1.9e-08 33.8 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AAG08532.1 - 0.0084 16.7 0.0 0.19 12.3 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 AAG08532.1 - 0.059 13.7 3.0 0.11 12.9 3.0 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Iron_traffic PF04362.14 AAG08533.1 - 1.8e-41 139.7 0.1 2e-41 139.6 0.1 1.0 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking AXIN1_TNKS_BD PF16646.5 AAG08533.1 - 0.11 13.5 0.0 0.13 13.2 0.0 1.3 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain GFO_IDH_MocA PF01408.22 AAG08534.1 - 3.8e-22 79.4 0.0 6.2e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAG08534.1 - 1.1e-09 38.3 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 AAG08534.1 - 4.2e-05 24.2 0.1 8.1e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AAG08534.1 - 0.00055 20.4 0.0 0.00092 19.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAG08534.1 - 0.0015 19.0 0.0 0.0035 17.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AAA_33 PF13671.6 AAG08534.1 - 0.03 14.5 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain adh_short_C2 PF13561.6 AAG08535.1 - 1.1e-51 175.6 0.0 1.3e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG08535.1 - 4.6e-41 140.4 0.0 5.8e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAG08535.1 - 0.0034 16.9 0.0 0.039 13.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAG08535.1 - 0.0046 16.4 0.0 0.0062 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF502 PF04367.13 AAG08536.1 - 8.9e-13 48.1 0.0 2.2e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF502) ABC_tran PF00005.27 AAG08537.1 - 1.2e-32 113.3 0.2 2.3e-32 112.4 0.1 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAG08537.1 - 1.4e-11 44.8 0.7 2.6e-07 30.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG08537.1 - 3.9e-08 33.0 0.3 1.2e-07 31.4 0.3 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AAG08537.1 - 4.5e-05 22.3 0.0 0.0021 16.8 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAG08537.1 - 0.0017 18.1 0.1 0.0033 17.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAG08537.1 - 0.0028 17.4 0.1 1.3 8.7 0.2 2.1 1 1 1 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 AAG08537.1 - 0.0029 16.8 0.0 0.0047 16.1 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 AAG08537.1 - 0.0063 16.8 0.1 0.11 12.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAG08537.1 - 0.0076 15.1 0.0 0.44 9.3 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 AAG08537.1 - 0.011 16.3 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAG08537.1 - 0.027 14.7 0.1 0.25 11.6 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 AAG08537.1 - 0.033 14.6 0.5 0.1 13.0 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 AAG08537.1 - 0.033 13.9 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 AAG08537.1 - 0.051 13.7 0.0 0.098 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAG08537.1 - 0.092 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 AAG08537.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 AAG08537.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain SBP_bac_3 PF00497.20 AAG08538.1 - 9.7e-66 221.4 0.5 1.1e-65 221.2 0.5 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAG08538.1 - 7.3e-11 42.3 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF2642 PF10842.8 AAG08538.1 - 0.021 14.7 0.0 0.068 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) BPD_transp_1 PF00528.22 AAG08539.1 - 8.8e-20 71.2 7.9 1.2e-19 70.8 7.9 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG08540.1 - 3.9e-21 75.6 12.9 3.9e-21 75.6 12.9 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 AAG08540.1 - 0.63 10.5 12.0 0.76 10.3 4.6 2.9 2 1 0 2 2 2 0 FtsX-like permease family Methyltransf_32 PF13679.6 AAG08541.1 - 5.4e-14 52.5 1.7 6.3e-13 49.0 1.7 2.2 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 AAG08541.1 - 0.48 9.9 1.0 3.3 7.2 0.0 2.4 2 1 0 3 3 3 0 Methyltransferase TRM13 MarR PF01047.22 AAG08542.1 - 7.9e-13 48.1 0.2 1.7e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AAG08542.1 - 2.4e-12 46.6 0.1 5.8e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAG08542.1 - 1.8e-07 31.5 0.0 3.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AAG08542.1 - 0.0015 18.1 0.0 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 AAG08542.1 - 0.0043 17.2 0.0 0.022 14.9 0.0 1.9 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain FeoC PF09012.10 AAG08542.1 - 0.027 14.5 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator TrmB PF01978.19 AAG08542.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 AAG08542.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix B-block_TFIIIC PF04182.12 AAG08542.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.5 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC OEP PF02321.18 AAG08543.1 - 1.8e-41 142.0 32.4 6.7e-23 81.5 17.0 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_D23 PF16576.5 AAG08544.1 - 1.3e-17 63.8 5.4 5.7e-16 58.4 5.4 2.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAG08544.1 - 1.4e-16 61.1 2.7 1.2e-14 54.9 0.2 3.2 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.20 AAG08544.1 - 5.1e-16 58.3 7.6 7.4e-15 54.6 7.6 2.7 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAG08544.1 - 1.9e-12 46.8 9.7 2.1e-09 37.1 1.2 3.6 3 0 0 3 3 3 2 Biotin-lipoyl like OEP PF02321.18 AAG08544.1 - 6.5e-06 26.1 1.0 6.5e-06 26.1 1.0 2.6 3 0 0 3 3 3 1 Outer membrane efflux protein Biotin_lipoyl PF00364.22 AAG08544.1 - 0.00043 20.1 0.7 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme Spc7 PF08317.11 AAG08544.1 - 0.038 12.9 0.4 0.054 12.4 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LXG PF04740.12 AAG08544.1 - 0.081 12.6 3.9 0.035 13.8 1.3 1.7 2 1 0 2 2 2 0 LXG domain of WXG superfamily OB_aCoA_assoc PF01796.17 AAG08544.1 - 0.14 12.2 0.3 17 5.5 0.0 3.0 3 0 0 3 3 3 0 DUF35 OB-fold domain, acyl-CoA-associated MFS_1 PF07690.16 AAG08545.1 - 3.5e-52 177.5 43.5 3.5e-52 177.5 43.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG08545.1 - 5.6e-07 28.8 11.0 5.6e-07 28.8 11.0 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 AAG08545.1 - 7.5e-07 27.9 13.6 7.5e-07 27.9 13.6 2.1 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 AAG08545.1 - 0.00036 19.0 16.9 0.053 11.8 1.2 3.5 2 2 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 AAG08545.1 - 0.00098 18.1 6.9 0.00098 18.1 6.9 2.2 2 0 0 2 2 2 1 MFS_1 like family GDP_Man_Dehyd PF16363.5 AAG08546.1 - 4.5e-101 338.6 0.0 5.1e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAG08546.1 - 1.9e-67 227.3 0.0 2.4e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG08546.1 - 3.8e-11 42.6 0.0 6.9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAG08546.1 - 2.1e-09 36.9 0.0 1.8e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAG08546.1 - 2.2e-08 33.6 0.0 2.6e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 AAG08546.1 - 7.2e-08 31.8 0.0 1.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 AAG08546.1 - 0.0019 17.7 0.0 0.5 9.8 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.17 AAG08547.1 - 8.2e-112 373.0 0.0 9.2e-112 372.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAG08547.1 - 1.1e-16 61.1 0.0 1.5e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAG08547.1 - 7.8e-11 41.9 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AAG08547.1 - 3.7e-05 23.0 0.0 7.8e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 AAG08547.1 - 0.0071 15.5 0.0 0.047 12.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NTP_transferase PF00483.23 AAG08548.1 - 3.3e-70 236.5 0.0 4.2e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAG08548.1 - 1.3e-09 38.6 0.0 1.8e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAG08548.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase dTDP_sugar_isom PF00908.17 AAG08549.1 - 4e-75 251.2 0.0 4.5e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase HATPase_c PF02518.26 AAG08550.1 - 1.7e-18 67.1 0.0 3.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAG08550.1 - 2.2e-15 57.2 0.0 2.2e-15 57.2 0.0 1.9 3 0 0 3 3 3 1 Cache domain HisKA PF00512.25 AAG08550.1 - 2.8e-08 33.7 0.7 2.8e-08 33.7 0.7 3.7 4 1 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAG08550.1 - 0.00023 21.0 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAG08550.1 - 0.0029 17.5 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAG08550.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF773 PF05600.12 AAG08550.1 - 0.097 11.4 4.1 0.17 10.6 4.1 1.3 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Sigma54_activat PF00158.26 AAG08551.1 - 4.5e-67 224.9 0.3 6.4e-67 224.5 0.3 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAG08551.1 - 4.5e-29 100.9 0.0 8.6e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAG08551.1 - 1.4e-23 83.6 0.0 3.5e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAG08551.1 - 1.6e-07 31.4 0.1 7.3e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) HTH_8 PF02954.19 AAG08551.1 - 1.9e-07 30.7 0.4 7e-07 28.9 0.0 2.3 2 0 0 2 2 1 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 AAG08551.1 - 5.2e-07 29.2 0.0 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_2 PF07724.14 AAG08551.1 - 1.6e-06 28.3 0.0 2.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) FleQ PF06490.11 AAG08551.1 - 8.4e-06 26.1 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ AAA PF00004.29 AAG08551.1 - 0.0011 19.4 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAG08551.1 - 0.0045 16.4 1.6 1.3 8.3 0.0 2.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI HTH_17 PF12728.7 AAG08551.1 - 0.074 13.3 0.1 0.62 10.3 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain C4bp_oligo PF18453.1 AAG08551.1 - 0.12 12.6 0.2 0.28 11.4 0.2 1.6 1 0 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha AAA_22 PF13401.6 AAG08551.1 - 0.22 11.8 2.3 25 5.1 0.2 3.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAG08551.1 - 1.1 9.6 8.4 0.13 12.7 2.2 2.7 3 1 0 3 3 3 0 AAA ATPase domain DctP PF03480.13 AAG08552.1 - 9.7e-114 379.5 2.0 1.1e-113 379.3 2.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Metal_resist PF13801.6 AAG08552.1 - 0.04 14.1 0.2 0.13 12.4 0.1 1.9 1 1 1 2 2 2 0 Heavy-metal resistance HTH_22 PF13309.6 AAG08552.1 - 0.15 12.2 0.3 0.47 10.6 0.2 1.9 2 0 0 2 2 2 0 HTH domain DctQ PF04290.12 AAG08553.1 - 2.9e-22 79.0 6.2 2.9e-22 79.0 6.2 2.0 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DctM PF06808.12 AAG08554.1 - 7.2e-125 417.1 58.5 8.3e-125 416.9 58.5 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component FAM176 PF14851.6 AAG08554.1 - 0.069 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 FAM176 family AA_permease_2 PF13520.6 AAG08555.1 - 1e-76 258.5 38.0 1.2e-76 258.2 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAG08555.1 - 3.1e-19 68.9 33.9 4.3e-19 68.5 33.9 1.2 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AAG08555.1 - 2.4e-06 26.6 13.9 2.4e-06 26.6 13.9 2.1 1 1 0 1 1 1 1 Spore germination protein DUF5389 PF17364.2 AAG08555.1 - 1.5 8.9 8.4 16 5.6 2.8 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5389) Amidinotransf PF02274.17 AAG08556.1 - 5.2e-119 397.3 0.0 6e-119 397.1 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase PAD_porph PF04371.15 AAG08556.1 - 0.017 14.5 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase LURAP PF14854.6 AAG08556.1 - 0.088 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Leucine rich adaptor protein OTCace PF00185.24 AAG08557.1 - 2.4e-54 183.7 0.0 4.5e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AAG08557.1 - 7e-46 155.9 0.1 9.8e-46 155.4 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_4 PF02056.16 AAG08557.1 - 0.024 14.2 0.0 0.067 12.7 0.0 1.7 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase AA_kinase PF00696.28 AAG08558.1 - 4.4e-26 91.9 0.0 1.3e-25 90.4 0.0 1.7 1 1 0 1 1 1 1 Amino acid kinase family ketoacyl-synt PF00109.26 AAG08559.1 - 3.8e-13 49.6 0.0 9.7e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAG08559.1 - 4.3e-11 42.9 0.3 1.2e-10 41.5 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 AAG08559.1 - 0.028 14.3 0.2 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Inositol_P PF00459.25 AAG08560.1 - 5.7e-48 163.8 0.0 7.1e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Anticodon_1 PF08264.13 AAG08560.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA NUDIX PF00293.28 AAG08561.1 - 7.2e-14 52.0 0.1 1.6e-13 50.9 0.1 1.5 2 0 0 2 2 2 1 NUDIX domain HAD_2 PF13419.6 AAG08562.1 - 1.6e-13 51.2 0.0 2.4e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAG08562.1 - 2.3e-09 37.9 0.9 3.2e-09 37.5 0.9 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG08562.1 - 5.8e-09 36.5 0.0 8.9e-06 26.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAG08562.1 - 7.4e-05 22.8 0.4 0.00041 20.4 0.4 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 AAG08562.1 - 0.00054 19.8 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase BON PF04972.17 AAG08563.1 - 4.1e-13 49.4 3.7 5.8e-13 48.9 3.7 1.2 1 0 0 1 1 1 1 BON domain LysM PF01476.20 AAG08563.1 - 4.4e-12 45.9 0.0 1.2e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 LysM domain Phage_tail_X PF05489.12 AAG08563.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X LysR_substrate PF03466.20 AAG08564.1 - 3.4e-34 118.1 5.7 5.3e-34 117.4 5.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08564.1 - 3.2e-16 59.0 0.7 1.5e-15 56.8 0.5 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG08564.1 - 0.00014 21.6 0.1 0.0004 20.1 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AAG08564.1 - 0.00016 21.7 1.0 0.00068 19.6 1.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAG08564.1 - 0.011 15.6 0.3 0.048 13.5 0.1 2.1 2 0 0 2 2 2 0 MarR family FdhD-NarQ PF02634.15 AAG08565.1 - 3.1e-67 226.7 0.0 3.8e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family Molybdopterin PF00384.22 AAG08566.1 - 5.8e-23 81.5 0.0 8.6e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAG08566.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Gly-zipper_YMGG PF13441.6 AAG08567.1 - 7.5e-08 32.0 58.8 9.5e-05 22.1 27.7 2.2 2 0 0 2 2 2 2 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAG08567.1 - 9.9e-08 31.9 97.1 0.00091 19.2 29.2 2.6 1 1 2 3 3 3 3 Glycine zipper Rick_17kDa_Anti PF05433.15 AAG08567.1 - 0.002 17.9 63.5 0.014 15.2 32.3 2.5 1 1 2 3 3 3 3 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AAG08568.1 - 2.5e-09 36.7 68.8 9e-06 25.3 26.7 2.4 2 0 0 2 2 2 2 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAG08568.1 - 8.2e-08 32.1 71.9 2.3e-05 24.3 27.3 2.6 2 1 1 3 3 3 3 Glycine zipper Rick_17kDa_Anti PF05433.15 AAG08568.1 - 2.7e-06 27.1 76.5 0.0002 21.1 31.4 2.8 1 1 3 4 4 4 4 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 AAG08568.1 - 6.5e-05 22.6 67.6 0.0051 16.6 27.4 2.5 2 0 0 2 2 2 2 Glycine-zipper domain CM_2 PF01817.21 AAG08569.1 - 1.6e-08 34.8 0.4 3.3e-08 33.8 0.2 1.6 2 0 0 2 2 2 1 Chorismate mutase type II Kinin PF08260.11 AAG08569.1 - 0.28 11.8 1.6 0.65 10.7 1.6 1.6 1 0 0 1 1 1 0 Insect kinin peptide 4HBT PF03061.22 AAG08570.1 - 5.7e-15 55.4 0.1 7.8e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAG08570.1 - 2.6e-13 50.5 0.0 3.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 AAG08570.1 - 5.5e-05 22.6 0.1 0.0012 18.2 0.2 2.1 2 0 0 2 2 2 1 Acyl-ACP thioesterase Fe-ADH PF00465.19 AAG08571.1 - 3.2e-114 381.5 0.9 3.7e-114 381.3 0.9 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AAG08571.1 - 1.1e-13 51.5 0.0 2.5e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Acyl-CoA_dh_C PF12806.7 AAG08572.1 - 1.3e-29 102.8 1.1 2.6e-29 101.9 1.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAG08572.1 - 3.1e-24 85.9 2.6 3.8e-23 82.3 2.6 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAG08572.1 - 4.2e-18 65.3 0.0 7.3e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAG08572.1 - 3.6e-13 50.2 0.1 8.9e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 AAG08572.1 - 2e-10 40.5 0.1 4.6e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 AAG08572.1 - 4.2e-06 27.1 0.6 2.9e-05 24.4 0.6 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain OpcA_G6PD_assem PF10128.9 AAG08572.1 - 0.0065 16.0 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase subunit 3HCDH_N PF02737.18 AAG08573.1 - 6.4e-60 202.1 0.1 8.5e-60 201.7 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AAG08573.1 - 6.5e-33 113.2 0.3 6.5e-23 81.2 0.2 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AAG08573.1 - 0.00019 21.7 0.3 0.00056 20.1 0.3 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 AAG08573.1 - 0.0086 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 AAG08573.1 - 0.0093 16.5 0.7 0.034 14.7 0.7 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Methyltransf_12 PF08242.12 AAG08573.1 - 0.029 15.1 0.0 0.059 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain XdhC_C PF13478.6 AAG08573.1 - 0.042 14.4 0.5 0.098 13.2 0.2 1.9 2 1 0 2 2 2 0 XdhC Rossmann domain LysR_substrate PF03466.20 AAG08574.1 - 4e-28 98.2 8.0 4e-28 98.2 8.0 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08574.1 - 2.2e-19 69.2 2.2 3.8e-19 68.4 1.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAG08574.1 - 6.5e-05 22.6 1.5 0.00019 21.2 0.9 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAG08574.1 - 0.00048 19.9 1.1 0.0015 18.4 1.1 1.9 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 AAG08574.1 - 0.0024 18.0 0.1 0.006 16.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAG08574.1 - 0.025 14.4 0.2 0.048 13.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.6 AAG08574.1 - 0.042 13.3 0.5 0.22 11.0 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 AAG08574.1 - 0.042 13.9 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.10 AAG08574.1 - 0.14 12.0 2.2 0.38 10.6 2.2 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AAG08574.1 - 0.18 11.4 0.6 0.46 10.1 0.6 1.8 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Nitroreductase PF00881.24 AAG08575.1 - 2e-33 115.8 0.1 2.3e-33 115.6 0.1 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAG08575.1 - 8.5e-08 32.0 0.0 0.0076 15.8 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase PEPCK_ATP PF01293.20 AAG08577.1 - 2.2e-188 626.7 0.0 2.6e-188 626.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 AAG08577.1 - 0.041 14.3 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AAG08577.1 - 0.077 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAG08577.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAG08577.1 - 0.33 10.7 1.3 0.58 9.9 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain HSP33 PF01430.19 AAG08578.1 - 1.1e-82 277.4 0.0 1.3e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein PAP2 PF01569.21 AAG08579.1 - 5.8e-13 48.8 1.4 5.8e-13 48.8 1.4 2.6 1 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AAG08579.1 - 0.0079 15.9 9.3 0.0079 15.9 9.3 2.2 2 1 0 2 2 2 1 PAP2 superfamily YGGT PF02325.17 AAG08579.1 - 0.064 13.7 0.0 0.064 13.7 0.0 3.4 4 1 0 4 4 4 0 YGGT family GspL_C PF12693.7 AAG08579.1 - 2.1 8.2 6.5 10 5.9 3.7 2.3 2 0 0 2 2 2 0 GspL periplasmic domain S4 PF01479.25 AAG08580.1 - 5.9e-10 38.7 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain Zn_protease PF05618.11 AAG08581.1 - 1.1e-45 154.8 0.0 1.3e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease Asp_protease_2 PF13650.6 AAG08581.1 - 0.1 13.2 0.1 3.1 8.5 0.1 2.3 1 1 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 AAG08581.1 - 0.14 12.8 0.1 3.9 8.1 0.1 2.2 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RimK PF08443.11 AAG08582.1 - 8.4e-69 230.9 0.0 1.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Rimk_N PF18030.1 AAG08582.1 - 2.6e-46 155.9 0.0 4.7e-46 155.1 0.0 1.4 1 0 0 1 1 1 1 RimK PreATP-grasp domain GSH-S_ATP PF02955.16 AAG08582.1 - 1.6e-16 60.2 0.1 2.8e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 AAG08582.1 - 3.6e-07 29.7 0.0 0.013 14.7 0.0 2.8 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 AAG08582.1 - 5.3e-07 29.8 0.0 8.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAG08582.1 - 0.00064 19.3 0.1 0.0075 15.8 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_YheCD PF14398.6 AAG08582.1 - 0.0028 17.0 0.0 0.23 10.7 0.1 2.8 1 1 2 3 3 3 1 YheC/D like ATP-grasp R2K_3 PF14243.6 AAG08582.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Peptidase_S66 PF02016.15 AAG08583.1 - 9.5e-31 106.4 0.0 1.5e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 AAG08583.1 - 1.8e-22 80.2 0.0 2.8e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain HATPase_c PF02518.26 AAG08584.1 - 1.5e-19 70.5 0.0 4.1e-19 69.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG08584.1 - 1.9e-11 43.8 0.8 4.2e-11 42.7 0.8 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAG08584.1 - 4.4e-10 39.8 0.3 1.5e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 HAMP domain HATPase_c_5 PF14501.6 AAG08584.1 - 0.0018 18.1 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 2 GHKL domain HATPase_c_3 PF13589.6 AAG08584.1 - 0.041 13.7 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAG08584.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 AAG08585.1 - 2.7e-31 108.0 0.0 4.1e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG08585.1 - 1.5e-22 79.4 0.4 3.5e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AAG08585.1 - 9e-05 22.8 0.0 0.00021 21.6 0.0 1.6 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ TusA PF01206.17 AAG08585.1 - 0.0046 16.8 0.1 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 Sulfurtransferase TusA DUF43 PF01861.16 AAG08585.1 - 0.025 13.8 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain FliT PF05400.13 AAG08585.1 - 0.037 14.8 1.0 5.4 7.9 0.2 2.7 2 0 0 2 2 2 0 Flagellar protein FliT MEDS PF14417.6 AAG08585.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Phage_TAC_6 PF09550.10 AAG08585.1 - 0.9 10.0 5.3 0.96 9.9 0.0 3.0 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC Tex_N PF09371.10 AAG08586.1 - 2.7e-65 219.4 1.5 3.1e-65 219.3 0.4 1.6 2 0 0 2 2 2 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 AAG08586.1 - 2.1e-53 180.1 0.0 4.3e-53 179.1 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 AAG08586.1 - 7.5e-30 103.0 0.7 4.4e-29 100.5 0.2 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_9 PF17674.1 AAG08586.1 - 1.6e-26 93.0 0.1 5.4e-26 91.3 0.1 2.0 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 AAG08586.1 - 1.4e-20 73.4 1.9 2.7e-20 72.5 1.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 AAG08586.1 - 5.7e-07 29.4 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 AAG08586.1 - 1.6e-06 28.4 0.0 3.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 AAG08586.1 - 0.00011 21.7 0.1 0.00025 20.5 0.1 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_6 PF14579.6 AAG08586.1 - 0.013 15.8 0.0 0.042 14.1 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif 4HBT PF03061.22 AAG08587.1 - 2e-21 76.1 0.6 2.8e-21 75.7 0.6 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AAG08587.1 - 2.2e-10 40.8 0.0 2.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AAG08587.1 - 7.3e-08 33.0 0.5 8.4e-08 32.8 0.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Glu_cys_ligase PF04262.14 AAG08588.1 - 2.1e-169 563.0 0.0 2.6e-169 562.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase AA_kinase PF00696.28 AAG08589.1 - 6.5e-19 68.5 0.1 1.1e-18 67.8 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 AAG08589.1 - 1.1e-09 38.5 1.0 3.1e-09 37.1 0.2 2.1 2 1 1 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG08589.1 - 8.2e-08 32.6 0.0 3.7e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG08589.1 - 2.8e-05 24.0 0.0 8.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MarC PF01914.17 AAG08590.1 - 2.1e-49 167.7 7.1 2.6e-49 167.4 7.1 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein LysE PF01810.18 AAG08590.1 - 0.00064 19.2 5.0 0.0012 18.3 5.0 1.4 1 1 0 1 1 1 1 LysE type translocator CPP1-like PF11833.8 AAG08590.1 - 1.9 8.1 9.7 0.092 12.4 2.7 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Peptidase_M20 PF01546.28 AAG08591.1 - 6e-32 111.0 0.0 7.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAG08591.1 - 2.2e-26 91.9 0.0 3.2e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AAG08591.1 - 0.067 12.9 0.0 0.37 10.4 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M28 PHO4 PF01384.20 AAG08592.1 - 6.3e-113 377.2 34.6 7.9e-113 376.9 34.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 AAG08592.1 - 0.1 12.4 0.6 21 5.0 0.1 3.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain PhoU_div PF01865.16 AAG08593.1 - 1.1e-59 201.3 0.1 1.3e-59 201.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 zf-C2H2_12 PF18658.1 AAG08593.1 - 0.072 12.7 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger C2H2-type CYTH PF01928.21 AAG08594.1 - 3.9e-38 131.2 1.4 5.9e-38 130.6 1.4 1.3 1 0 0 1 1 1 1 CYTH domain T2SSE PF00437.20 AAG08595.1 - 1.9e-76 256.8 0.1 3e-76 256.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AAG08595.1 - 5.8e-16 58.7 1.0 2e-15 57.0 1.0 2.0 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_16 PF13191.6 AAG08595.1 - 2.9e-05 24.5 0.0 9.4e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAG08595.1 - 0.00046 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AAG08595.1 - 0.00066 19.6 0.7 0.041 13.8 0.3 2.6 2 0 0 2 2 2 1 NTPase Rad17 PF03215.15 AAG08595.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 AAG08595.1 - 0.0021 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG08595.1 - 0.0021 17.8 0.1 0.0046 16.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 AAG08595.1 - 0.003 17.1 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 AAG08595.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG08595.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAG08595.1 - 0.012 14.9 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 AAG08595.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAG08595.1 - 0.013 15.8 1.0 0.04 14.3 0.9 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 AAG08595.1 - 0.019 14.5 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 AAG08595.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 AAG08595.1 - 0.026 15.0 0.0 0.063 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Microtub_bd PF16796.5 AAG08595.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Microtubule binding ResIII PF04851.15 AAG08595.1 - 0.04 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 AAG08595.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 AAG08595.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 AAG08595.1 - 0.092 12.3 0.1 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAG08595.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 AAG08595.1 - 0.11 12.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase MobB PF03205.14 AAG08595.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HP1451_C PF18472.1 AAG08595.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 HP1451 C-terminal domain NfeD PF01957.18 AAG08596.1 - 6.9e-09 36.0 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding Phage_holin_3_6 PF07332.11 AAG08596.1 - 0.69 10.0 8.7 0.53 10.3 7.4 1.4 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2388 PF09498.10 AAG08597.1 - 1.8e-32 111.1 0.8 2.6e-32 110.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) GDC-P PF02347.16 AAG08598.1 - 7.6e-181 601.6 0.0 2.7e-174 580.0 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 AAG08598.1 - 3.9e-05 23.1 0.0 8.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAG08598.1 - 0.0011 17.9 0.0 0.0046 16.0 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V GCV_H PF01597.19 AAG08599.1 - 1.3e-41 141.3 0.0 1.4e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 AAG08599.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_T PF01571.21 AAG08600.1 - 2.5e-82 276.1 0.3 3.1e-82 275.8 0.3 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AAG08600.1 - 1.7e-16 59.9 0.2 5.6e-16 58.2 0.2 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain BPD_transp_1 PF00528.22 AAG08601.1 - 5.1e-19 68.7 49.5 8.8e-16 58.2 16.7 4.2 2 2 2 4 4 4 2 Binding-protein-dependent transport system inner membrane component SBP_bac_6 PF13343.6 AAG08602.1 - 1.6e-21 76.9 0.1 2.2e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAG08602.1 - 4.9e-20 72.5 0.4 6.7e-20 72.0 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAG08602.1 - 3.8e-16 59.6 0.2 6e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAG08602.1 - 2.2e-15 57.4 0.1 3.6e-15 56.7 0.1 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_3 PF00497.20 AAG08602.1 - 0.026 13.9 0.0 0.059 12.8 0.0 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAG08602.1 - 0.029 13.9 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.20 AAG08603.1 - 5.1e-42 143.6 5.9 8.8e-42 142.8 5.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08603.1 - 1.4e-21 76.1 1.9 4.4e-21 74.6 1.9 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SBP_bac_11 PF13531.6 AAG08603.1 - 3.5e-05 23.7 0.4 0.0024 17.6 0.4 2.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAG08603.1 - 0.0038 16.4 0.0 0.025 13.7 0.0 2.1 1 1 0 1 1 1 1 PBP superfamily domain MFS_1 PF07690.16 AAG08604.1 - 1.7e-35 122.6 39.0 1.7e-35 122.6 39.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1282 PF06930.12 AAG08604.1 - 5.9 6.6 10.8 0.18 11.6 3.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) Death PF00531.22 AAG08605.1 - 0.075 13.2 1.1 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Death domain FAD_binding_3 PF01494.19 AAG08606.1 - 4.5e-25 88.6 1.7 9.3e-25 87.6 1.7 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 AAG08606.1 - 1.1e-08 34.5 0.0 2.6e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 AAG08606.1 - 2.1e-07 30.3 4.2 3e-05 23.3 3.3 3.0 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AAG08606.1 - 0.00015 21.1 0.1 0.028 13.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG08606.1 - 0.0079 16.4 2.4 0.046 14.0 2.4 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAG08606.1 - 0.0084 15.7 3.0 0.0084 15.7 3.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AAG08606.1 - 0.027 14.5 0.5 0.98 9.4 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 AAG08606.1 - 0.032 14.1 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAG08606.1 - 0.037 13.4 0.1 0.44 9.9 0.0 2.4 2 1 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AAG08606.1 - 0.042 13.5 0.2 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 AAG08606.1 - 0.073 13.6 1.8 0.29 11.7 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AAG08606.1 - 0.086 11.7 2.3 1.9 7.3 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase XdhC_C PF13478.6 AAG08606.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain GIDA PF01134.22 AAG08606.1 - 0.13 11.3 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAG08606.1 - 0.13 11.6 0.3 0.18 11.1 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG08606.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 AAG08606.1 - 0.29 10.3 0.2 4.2 6.5 1.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 AAG08606.1 - 0.32 10.9 2.2 0.43 10.4 0.6 2.1 2 0 0 2 2 1 0 Rossmann-like domain HI0933_like PF03486.14 AAG08606.1 - 1.1 7.9 2.1 30 3.2 1.7 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 AAG08606.1 - 4.3 6.3 12.1 0.41 9.7 3.3 2.8 2 1 0 3 3 3 0 FAD binding domain DUF4442 PF14539.6 AAG08607.1 - 2.2e-30 105.5 0.0 2.5e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) YiiD_C PF09500.10 AAG08607.1 - 0.00068 19.5 0.0 0.0011 18.8 0.0 1.3 1 1 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) FAD_binding_3 PF01494.19 AAG08608.1 - 1.3e-18 67.4 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 AAG08608.1 - 8.9e-07 29.0 0.0 0.0063 16.5 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AAG08608.1 - 7.8e-05 22.0 0.1 0.0023 17.2 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAG08608.1 - 0.00026 20.7 3.0 0.00071 19.3 2.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG08608.1 - 0.0077 15.0 0.1 0.028 13.1 0.0 1.8 2 1 0 2 2 2 1 HI0933-like protein SE PF08491.10 AAG08608.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.12 AAG08608.1 - 0.049 12.7 0.0 0.72 8.8 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein DUF5372 PF17342.2 AAG08608.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5372) NAD_binding_8 PF13450.6 AAG08608.1 - 0.1 12.8 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_M24 PF00557.24 AAG08609.1 - 3.3e-65 219.7 0.4 1.2e-64 217.9 1.1 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 AAG08609.1 - 8.3e-37 125.7 0.0 1.6e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Cupin_2 PF07883.11 AAG08609.1 - 0.0026 17.5 0.1 0.31 10.8 0.0 2.9 3 0 0 3 3 3 1 Cupin domain Creatinase_N PF01321.18 AAG08609.1 - 0.082 13.6 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain AraC_binding PF02311.19 AAG08609.1 - 0.12 12.3 0.0 11 5.9 0.0 3.4 4 0 0 4 4 4 0 AraC-like ligand binding domain UPF0149 PF03695.13 AAG08610.1 - 8.6e-30 104.3 4.9 9.6e-30 104.1 4.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) EutK_C PF16365.5 AAG08610.1 - 0.033 14.2 0.1 0.081 13.0 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus APC_N_CC PF16689.5 AAG08611.1 - 0.02 15.0 2.5 0.03 14.4 2.5 1.6 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain ZapB PF06005.12 AAG08611.1 - 0.038 14.4 10.7 0.045 14.2 10.7 1.1 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 AAG08611.1 - 0.4 11.2 9.0 0.46 11.0 9.0 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 AAG08611.1 - 2.3 8.0 6.4 2.8 7.8 5.3 1.6 1 1 1 2 2 2 0 Septum formation initiator Matrilin_ccoil PF10393.9 AAG08611.1 - 3.1 7.7 6.1 2.1 8.3 1.4 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ZapA PF05164.13 AAG08612.1 - 3.1e-23 82.0 0.8 4.1e-23 81.6 0.8 1.2 1 0 0 1 1 1 1 Cell division protein ZapA 5-FTHF_cyc-lig PF01812.20 AAG08613.1 - 6.4e-39 133.7 0.0 7.2e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family EVE PF01878.18 AAG08614.1 - 6.7e-53 178.6 0.0 7.4e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 EVE domain ABC2_membrane_3 PF12698.7 AAG08615.1 - 1.4e-29 103.3 1.5 1.6e-29 103.1 1.5 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAG08615.1 - 2.1e-26 92.6 10.7 2.1e-26 92.6 10.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AAG08615.1 - 1.7e-12 47.3 5.1 2.6e-12 46.6 5.1 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAG08615.1 - 0.00057 19.9 6.0 0.0014 18.6 5.5 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 AAG08616.1 - 7.5e-57 191.7 0.0 9.6e-28 97.4 0.0 2.2 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 AAG08616.1 - 3.7e-43 147.9 4.0 5.2e-43 147.5 4.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 AAG08616.1 - 1.6e-20 74.1 1.3 5.1e-07 29.8 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 AAG08616.1 - 6.3e-19 68.3 8.0 9.9e-19 67.7 8.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAG08616.1 - 4e-18 65.6 9.7 4e-18 65.6 9.7 2.1 2 0 0 2 2 2 1 ABC-2 type transporter AAA_16 PF13191.6 AAG08616.1 - 2.4e-06 28.0 0.2 0.054 13.9 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 AAG08616.1 - 2.8e-06 27.4 0.0 0.0021 18.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 AAG08616.1 - 4.3e-05 23.2 0.1 0.41 10.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 AAG08616.1 - 8.4e-05 22.4 0.0 2.1 8.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain ABC2_membrane_4 PF12730.7 AAG08616.1 - 0.00081 19.4 10.1 0.0016 18.4 10.1 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein MMR_HSR1 PF01926.23 AAG08616.1 - 0.0065 16.5 0.0 0.82 9.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 AAG08616.1 - 0.0071 16.9 0.0 0.46 11.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAG08616.1 - 0.011 16.0 0.1 11 6.3 0.1 3.0 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 AAG08616.1 - 0.027 14.5 0.1 4 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) BCA_ABC_TP_C PF12399.8 AAG08616.1 - 0.03 14.2 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter SbcCD_C PF13558.6 AAG08616.1 - 0.043 14.0 0.0 39 4.6 0.0 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 AAG08616.1 - 0.049 13.4 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAG08616.1 - 0.06 13.7 0.1 5.5 7.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 AAG08616.1 - 0.075 13.0 0.0 3.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 AAG08616.1 - 0.088 13.0 0.8 16 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAG08616.1 - 0.09 13.2 0.1 13 6.2 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAG08616.1 - 0.2 11.8 0.1 21 5.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAG08616.1 - 0.23 11.2 0.0 5.4 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain HlyD_3 PF13437.6 AAG08617.1 - 1.2e-16 61.3 8.1 2.4e-13 50.7 0.1 2.9 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAG08617.1 - 2.4e-13 49.7 2.5 2.4e-13 49.7 2.5 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAG08617.1 - 8.1e-13 48.1 12.6 1.1e-10 41.1 12.6 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AAG08617.1 - 0.00032 20.5 0.1 0.0069 16.2 0.1 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme BLOC1S3 PF15753.5 AAG08617.1 - 0.0089 16.2 7.3 0.014 15.6 7.3 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 OEP PF02321.18 AAG08617.1 - 0.015 15.1 26.8 0.015 15.1 26.8 2.1 1 1 0 2 2 2 0 Outer membrane efflux protein Peptidase_M23 PF01551.22 AAG08617.1 - 0.024 14.8 0.1 0.34 11.1 0.0 2.7 2 1 1 3 3 3 0 Peptidase family M23 PTS_EIIA_1 PF00358.20 AAG08617.1 - 0.093 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 BST2 PF16716.5 AAG08617.1 - 0.21 12.2 18.8 2.8 8.6 3.0 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 TFIIA PF03153.13 AAG08617.1 - 0.22 11.5 9.3 0.28 11.1 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fez1 PF06818.15 AAG08617.1 - 0.8 10.1 9.9 1.5 9.3 9.9 1.4 1 0 0 1 1 1 0 Fez1 MscS_porin PF12795.7 AAG08617.1 - 1.4 8.4 32.9 0.16 11.5 10.4 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 AAG08617.1 - 1.8 7.9 24.4 5.3 6.3 24.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 AAG08617.1 - 3.6 6.4 16.5 0.17 10.7 6.8 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein HrpB7 PF09486.10 AAG08617.1 - 7.4 6.9 33.7 4.8 7.6 22.4 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 AAG08617.1 - 8.3 6.6 22.4 73 3.5 22.3 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FliL PF03748.14 AAG08618.1 - 3.3e-21 75.8 0.5 4e-21 75.5 0.5 1.1 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL Zwilch PF09817.9 AAG08618.1 - 0.013 13.9 0.2 0.017 13.6 0.2 1.0 1 0 0 1 1 1 0 RZZ complex, subunit zwilch ADH_zinc_N PF00107.26 AAG08619.1 - 2.4e-30 105.2 0.4 4.5e-30 104.3 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAG08619.1 - 6.6e-24 85.5 0.0 1.2e-23 84.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAG08619.1 - 9.9e-12 44.7 0.0 8.4e-11 41.7 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 AAG08619.1 - 0.0063 15.8 1.5 0.0097 15.2 1.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 AAG08619.1 - 0.0073 15.8 0.5 0.011 15.2 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 AAG08619.1 - 0.022 14.5 0.2 0.081 12.7 0.2 2.0 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.19 AAG08619.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 AAG08620.1 - 4.2e-55 187.1 31.6 3.8e-53 180.7 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.13 AAG08620.1 - 0.001 18.6 2.3 0.068 12.6 1.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF373) OATP PF03137.20 AAG08620.1 - 0.0062 14.9 0.0 0.0062 14.9 0.0 2.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1146 PF06612.11 AAG08620.1 - 0.012 15.6 0.1 9.8 6.3 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) Phage_holin_3_6 PF07332.11 AAG08620.1 - 2.3 8.3 0.0 2.3 8.3 0.0 4.8 3 2 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III NAD_binding_1 PF00175.21 AAG08621.1 - 3.9e-12 46.8 0.0 6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AAG08621.1 - 1.6e-07 31.2 2.0 3e-07 30.3 2.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AAG08621.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain UbiD PF01977.16 AAG08622.1 - 1e-174 581.2 0.0 1.2e-174 581.0 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Acyl_transf_3 PF01757.22 AAG08623.1 - 3.6e-30 105.2 32.4 3.9e-30 105.1 31.7 1.4 1 1 0 1 1 1 1 Acyltransferase family MerC PF03203.14 AAG08623.1 - 0.43 11.1 16.3 0.12 12.8 9.4 3.0 3 0 0 3 3 3 0 MerC mercury resistance protein Rho_RNA_bind PF07497.12 AAG08624.1 - 2.6e-32 110.5 0.0 4.5e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 AAG08624.1 - 3.7e-24 85.6 0.0 5.8e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 AAG08624.1 - 3.4e-15 55.7 3.0 5.1e-15 55.1 1.8 2.0 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain OB_RNB PF08206.11 AAG08624.1 - 0.00049 19.7 0.0 0.0015 18.2 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease B OB domain NACHT PF05729.12 AAG08624.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 AAG08624.1 - 0.006 16.2 0.0 0.019 14.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAG08624.1 - 0.026 14.8 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAG08624.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAG08624.1 - 0.16 12.0 0.2 3.7 7.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 AAG08625.1 - 1.1e-34 118.5 0.0 1.2e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAG08625.1 - 4.4e-09 36.8 0.1 1.1e-07 32.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AAG08625.1 - 2.6e-07 30.9 0.0 2.6e-05 24.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AAG08625.1 - 0.00013 21.7 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 AAG08625.1 - 0.00044 20.4 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 AAG08625.1 - 0.00091 19.1 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 AAG08625.1 - 0.0024 17.9 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 AAG08625.1 - 0.006 16.0 0.0 0.006 16.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 AAG08625.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family DUF836 PF05768.14 AAG08625.1 - 0.028 14.8 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 AAG08625.1 - 0.046 13.5 0.1 1.1 9.0 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Redoxin PF08534.10 AAG08625.1 - 0.061 13.0 0.1 0.78 9.4 0.1 2.0 1 1 1 2 2 2 0 Redoxin Thioredoxin_6 PF13848.6 AAG08625.1 - 0.087 12.7 0.0 0.35 10.8 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.11 AAG08625.1 - 0.14 12.1 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Ppx-GppA PF02541.16 AAG08626.1 - 4.5e-77 259.3 0.0 6.6e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF2489 PF10675.9 AAG08626.1 - 0.03 14.3 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) HD PF01966.22 AAG08626.1 - 0.051 13.8 1.1 0.13 12.5 1.1 1.7 1 0 0 1 1 1 0 HD domain PP_kinase_C_1 PF17941.1 AAG08627.1 - 2.3e-72 242.0 0.2 3.1e-70 235.1 0.0 2.2 1 1 1 2 2 2 2 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 AAG08627.1 - 4e-72 241.3 0.0 3.6e-71 238.2 0.0 2.1 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 AAG08627.1 - 1.1e-65 221.0 0.0 2.3e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.6 AAG08627.1 - 8.9e-36 122.5 0.6 2.1e-35 121.3 0.6 1.7 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 AAG08627.1 - 1.4e-13 50.8 0.0 7.1e-07 29.2 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain ALAD PF00490.21 AAG08628.1 - 1.3e-136 454.9 0.0 1.5e-136 454.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase SNARE_assoc PF09335.11 AAG08629.1 - 2e-18 67.0 2.2 3.9e-18 66.1 2.2 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein DJ-1_PfpI PF01965.24 AAG08630.1 - 1.1e-09 38.4 0.2 2.7e-09 37.0 0.2 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 AAG08630.1 - 0.026 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Catalase_C PF18011.1 AAG08630.1 - 0.063 12.9 0.1 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 C-terminal domain found in long catalases 4HBT PF03061.22 AAG08631.1 - 6.4e-19 68.1 0.1 1.4e-18 67.0 0.1 1.5 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 AAG08631.1 - 0.0033 17.6 0.0 0.022 14.9 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AAG08631.1 - 0.0052 17.1 0.1 0.01 16.1 0.1 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily DUF188 PF02639.14 AAG08632.1 - 1.8e-42 144.1 0.0 2e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 PIN_9 PF18477.1 AAG08632.1 - 0.02 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 PIN like domain FTR1 PF03239.14 AAG08633.1 - 7e-17 61.5 25.7 3.3e-12 46.2 6.4 2.2 1 1 1 2 2 2 2 Iron permease FTR1 family Cytochrome_CBB3 PF13442.6 AAG08633.1 - 5.8e-12 45.7 0.0 1.4e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAG08633.1 - 8.6e-08 33.2 0.0 3e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 Cytochrome c Phage_tail_APC PF16778.5 AAG08633.1 - 0.014 15.2 0.3 0.014 15.2 0.3 2.7 4 0 0 4 4 4 0 Phage tail assembly chaperone protein LysE PF01810.18 AAG08634.1 - 7.2e-33 113.7 11.1 8.5e-33 113.4 11.1 1.1 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAG08635.1 - 4e-50 170.0 13.6 5.1e-50 169.7 13.6 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family SseC PF04888.12 AAG08635.1 - 0.45 10.1 4.8 0.57 9.7 4.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4781 PF16013.5 AAG08635.1 - 1.5 7.6 4.9 2.3 6.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) SirB PF04247.12 AAG08635.1 - 1.8 8.7 8.5 0.65 10.1 4.3 2.3 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MS_channel PF00924.18 AAG08636.1 - 2.5e-14 53.3 0.1 3.5e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel TM_helix PF05552.12 AAG08636.1 - 0.0031 17.4 6.5 0.016 15.2 0.6 2.7 2 1 0 2 2 2 2 Conserved TM helix GCD14_N PF14801.6 AAG08636.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Flu_M2 PF00599.17 AAG08636.1 - 0.12 12.5 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Influenza Matrix protein (M2) GAIN PF16489.5 AAG08636.1 - 0.25 10.7 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain ABC_tran PF00005.27 AAG08637.1 - 1.1e-44 152.3 0.0 5.7e-21 75.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 AAG08637.1 - 6.1e-30 103.1 5.3 6.1e-30 103.1 5.3 2.4 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAG08637.1 - 3.9e-16 59.7 10.4 0.00015 21.7 0.3 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG08637.1 - 6.2e-11 42.2 0.2 0.0016 18.0 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_CTD PF16326.5 AAG08637.1 - 1.2e-06 28.7 4.1 1.2e-06 28.7 4.1 4.5 3 2 3 6 6 6 1 ABC transporter C-terminal domain RsgA_GTPase PF03193.16 AAG08637.1 - 9.6e-06 25.6 0.1 0.076 12.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 AAG08637.1 - 1.3e-05 24.9 0.6 0.094 12.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAG08637.1 - 6.1e-05 23.1 0.2 0.15 12.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 AAG08637.1 - 0.00038 21.0 0.1 0.4 11.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 AAG08637.1 - 0.0012 19.0 7.7 0.19 11.9 0.0 3.7 4 0 0 4 4 3 1 AAA domain ATG16 PF08614.11 AAG08637.1 - 0.0016 18.7 9.8 0.0016 18.7 9.8 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) MeaB PF03308.16 AAG08637.1 - 0.0027 16.7 1.2 0.08 11.9 0.2 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 AAG08637.1 - 0.0052 16.5 0.3 0.33 10.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AAG08637.1 - 0.0069 16.6 2.8 0.61 10.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.14 AAG08637.1 - 0.012 15.6 0.2 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAG08637.1 - 0.02 15.3 13.3 0.64 10.4 0.2 3.9 3 1 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.13 AAG08637.1 - 0.032 13.4 0.1 3.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 AAG08637.1 - 0.042 14.2 0.1 1.5 9.2 0.1 2.4 2 0 0 2 2 2 0 RNA helicase DLIC PF05783.11 AAG08637.1 - 0.05 12.4 0.3 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) KAP_NTPase PF07693.14 AAG08637.1 - 0.051 12.8 0.0 7.9 5.6 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain FliD_N PF02465.18 AAG08637.1 - 0.064 14.0 1.1 0.18 12.5 1.1 1.8 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus AAA_15 PF13175.6 AAG08637.1 - 0.064 13.0 0.2 8 6.1 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 AAG08637.1 - 0.064 11.9 8.8 0.65 8.6 0.0 3.9 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 AAG08637.1 - 0.068 13.1 0.5 3.3 7.6 0.0 3.2 3 0 0 3 3 3 0 NACHT domain SlyX PF04102.12 AAG08637.1 - 0.079 13.6 0.3 0.079 13.6 0.3 4.2 5 0 0 5 5 3 0 SlyX AAA_22 PF13401.6 AAG08637.1 - 0.08 13.2 4.4 2.6 8.3 0.1 3.4 3 1 0 3 3 2 0 AAA domain AAA PF00004.29 AAG08637.1 - 0.12 12.8 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 AAG08637.1 - 0.17 12.1 0.2 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 AAG08637.1 - 0.17 11.5 0.5 11 5.6 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 AAG08637.1 - 0.24 10.7 2.2 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 AAG08637.1 - 0.76 10.2 0.1 0.56 10.7 1.0 4.4 4 1 0 4 4 3 0 AAA domain ZapB PF06005.12 AAG08637.1 - 1.9 9.0 17.7 1.7 9.2 0.9 4.1 3 1 0 3 3 3 0 Cell division protein ZapB PT PF04886.12 AAG08638.1 - 4.2e-06 26.2 56.7 0.26 10.9 1.9 7.7 1 1 3 4 4 4 2 PT repeat IMD PF08397.11 AAG08638.1 - 0.025 14.0 4.1 0.036 13.4 4.1 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF3584 PF12128.8 AAG08638.1 - 0.088 10.3 7.8 0.11 10.0 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PDE4_UCR PF18100.1 AAG08638.1 - 0.14 12.8 0.9 0.38 11.4 0.9 1.7 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Fib_alpha PF08702.10 AAG08638.1 - 0.15 12.3 1.5 0.32 11.2 0.1 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ThiD2 PF17792.1 AAG08638.1 - 0.19 12.2 4.1 0.34 11.4 4.1 1.3 1 0 0 1 1 1 0 ThiD2 family ANAPC15 PF15243.6 AAG08638.1 - 0.24 11.8 0.9 0.66 10.4 0.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 OmpH PF03938.14 AAG08638.1 - 0.26 11.6 13.6 0.53 10.6 13.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1682 PF07946.14 AAG08638.1 - 0.26 10.5 6.8 0.47 9.6 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CsbD PF05532.12 AAG08638.1 - 0.68 9.9 14.5 0.23 11.4 0.6 3.6 2 1 1 3 3 3 0 CsbD-like V_ATPase_I PF01496.19 AAG08638.1 - 0.89 7.4 2.3 1.2 7.0 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 AAG08638.1 - 1.2 8.0 9.5 1.6 7.5 9.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Herpes_UL6 PF01763.16 AAG08638.1 - 1.2 7.5 2.9 1.6 7.1 2.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3496 PF12001.8 AAG08638.1 - 1.9 8.9 5.1 3.4 8.1 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Atg14 PF10186.9 AAG08638.1 - 2.8 7.0 8.7 3.8 6.5 8.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ApoLp-III PF07464.11 AAG08638.1 - 4.9 7.2 17.8 0.12 12.4 9.7 2.5 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) FKBP_C PF00254.28 AAG08639.1 - 1.8e-18 66.6 0.0 3.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AAG08639.1 - 1.2e-06 29.4 0.0 2.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Rsd_AlgQ PF04353.13 AAG08640.1 - 2.3e-53 180.2 0.1 2.6e-53 180.0 0.1 1.0 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DsbB PF02600.16 AAG08641.1 - 6.2e-39 133.8 12.0 7e-39 133.6 12.0 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB PMP1_2 PF08114.11 AAG08641.1 - 0.13 12.0 11.2 0.97 9.2 0.2 3.7 4 0 0 4 4 4 0 ATPase proteolipid family HemY_N PF07219.13 AAG08642.1 - 1.3e-25 89.7 2.6 1.3e-25 89.7 2.6 3.7 2 1 1 3 3 3 1 HemY protein N-terminus TPR_19 PF14559.6 AAG08642.1 - 7.8e-14 51.9 19.2 0.00016 22.1 2.7 4.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 AAG08642.1 - 2e-09 37.5 28.4 0.087 13.7 0.1 7.3 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 AAG08642.1 - 4.5e-09 35.7 16.6 1.2 9.4 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AAG08642.1 - 5.5e-07 29.7 0.4 0.45 10.8 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AAG08642.1 - 1e-06 28.9 21.6 0.077 13.3 3.4 5.5 4 3 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 AAG08642.1 - 8.2e-06 25.6 2.4 23 5.5 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 AAG08642.1 - 2.6e-05 24.8 26.3 0.022 15.4 6.3 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat Coatomer_E PF04733.14 AAG08642.1 - 0.0018 17.8 0.1 0.9 8.9 0.0 2.3 2 0 0 2 2 2 2 Coatomer epsilon subunit HrpB1_HrpK PF09613.10 AAG08642.1 - 0.0091 15.6 4.8 0.013 15.1 0.7 3.2 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 AAG08642.1 - 0.018 14.8 0.8 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain DUF2760 PF10816.8 AAG08642.1 - 0.027 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) TPR_6 PF13174.6 AAG08642.1 - 0.028 15.1 12.3 1.5 9.7 0.4 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 AAG08642.1 - 0.03 14.5 0.3 0.03 14.5 0.3 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAG08642.1 - 0.045 13.6 7.1 8.2 6.4 0.6 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAG08642.1 - 0.047 14.1 2.1 14 6.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAG08642.1 - 0.057 14.1 0.0 0.057 14.1 0.0 6.8 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAG08642.1 - 0.9 9.7 12.5 71 3.8 0.0 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat HemX PF04375.14 AAG08643.1 - 1.7e-98 330.0 16.3 2e-98 329.8 16.3 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2730 PF10805.8 AAG08643.1 - 0.00012 22.1 0.1 0.00034 20.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DivIC PF04977.15 AAG08643.1 - 0.0093 15.7 1.2 0.0093 15.7 1.2 2.7 4 0 0 4 4 4 1 Septum formation initiator CENP-H PF05837.12 AAG08643.1 - 0.012 16.0 5.3 0.012 16.0 5.3 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Wzy_C_2 PF11846.8 AAG08643.1 - 0.065 13.1 2.5 0.21 11.5 0.0 2.4 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Nup88 PF10168.9 AAG08643.1 - 0.51 8.1 3.3 0.68 7.7 3.3 1.1 1 0 0 1 1 1 0 Nuclear pore component HEM4 PF02602.15 AAG08644.1 - 3.4e-37 128.0 0.0 3.9e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD B12-binding PF02310.19 AAG08644.1 - 0.12 12.4 0.0 0.99 9.4 0.0 2.3 3 0 0 3 3 3 0 B12 binding domain Porphobil_deam PF01379.20 AAG08645.1 - 3.1e-81 271.7 0.0 3.8e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AAG08645.1 - 9.6e-24 83.6 0.2 1.7e-23 82.8 0.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain LysR_substrate PF03466.20 AAG08645.1 - 0.0024 17.3 1.6 0.076 12.4 0.1 3.0 2 1 0 3 3 3 1 LysR substrate binding domain GTP_cyclohydroI PF01227.22 AAG08645.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I Response_reg PF00072.24 AAG08646.1 - 3.4e-27 94.8 0.0 4.8e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain LytTR PF04397.15 AAG08646.1 - 2.2e-21 75.9 0.0 3.7e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 LytTr DNA-binding domain Secretin_N PF03958.17 AAG08646.1 - 0.13 12.6 0.2 4.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain His_kinase PF06580.13 AAG08647.1 - 4.2e-23 81.5 0.0 7.4e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase DUF2681 PF10883.8 AAG08647.1 - 0.027 14.9 0.5 0.053 13.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Lyase_1 PF00206.20 AAG08648.1 - 1.3e-77 261.3 0.0 1.6e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 AAG08648.1 - 2.9e-26 92.0 0.0 7.8e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF2205 PF10224.9 AAG08648.1 - 0.11 12.6 0.1 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Short coiled-coil protein DUF2157 PF09925.9 AAG08649.1 - 0.47 10.2 5.3 0.79 9.5 5.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) NrsF PF06532.11 AAG08649.1 - 5.8 6.6 7.3 0.093 12.4 0.4 1.4 2 0 0 2 2 2 0 Negative regulator of sigma F Cation_ATPase_C PF00689.21 AAG08649.1 - 8 6.1 11.8 12 5.5 11.8 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2070 PF09843.9 AAG08649.1 - 8.2 4.6 6.4 11 4.2 6.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_GPD PF05954.11 AAG08651.1 - 6.4e-79 265.4 0.6 6.4e-79 265.4 0.6 1.5 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 AAG08651.1 - 0.00015 21.6 0.9 0.0014 18.5 0.9 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) Phage_base_V PF04717.12 AAG08651.1 - 0.013 15.4 0.0 0.08 12.9 0.0 2.1 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector T6SS_HCP PF05638.12 AAG08652.1 - 5.6e-37 127.0 0.1 6.4e-37 126.8 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp CorA PF01544.18 AAG08653.1 - 5.4e-54 183.5 0.2 6.3e-54 183.3 0.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1841 PF08897.11 AAG08654.1 - 0.1 12.6 0.1 0.11 12.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) SBP_bac_3 PF00497.20 AAG08655.1 - 1.5e-15 57.2 0.0 2.1e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 AzlD PF05437.12 AAG08655.1 - 0.042 14.0 0.5 0.075 13.2 0.5 1.3 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) PsiE PF06146.12 AAG08656.1 - 2.4e-15 56.7 0.0 2.7e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate-starvation-inducible E Adenylate_cycl PF01295.18 AAG08657.1 - 5.9e-120 401.7 0.0 7.3e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate cyclase, class-I Adenyl_cycl_N PF12633.7 AAG08657.1 - 1.1e-71 240.9 0.0 1.6e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase NT domain DIL PF01843.19 AAG08657.1 - 0.052 13.8 0.0 39 4.6 0.0 3.3 3 0 0 3 3 3 0 DIL domain AftA_C PF12249.8 AAG08657.1 - 0.22 11.2 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal GreA_GreB PF01272.19 AAG08659.1 - 4.7e-20 71.3 0.0 7.4e-20 70.6 0.0 1.3 1 1 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Rnk_N PF14760.6 AAG08659.1 - 3.3e-15 56.3 1.2 5e-15 55.7 1.2 1.3 1 0 0 1 1 1 1 Rnk N-terminus Frataxin_Cyay PF01491.16 AAG08660.1 - 1.7e-22 79.5 0.0 1.9e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain LPAM_2 PF13627.6 AAG08661.1 - 3e-08 33.3 7.5 4.7e-08 32.6 7.5 1.4 1 1 0 1 1 1 1 Prokaryotic lipoprotein-attachment site LPAM_1 PF08139.12 AAG08661.1 - 0.05 14.1 3.2 0.05 14.1 3.2 1.4 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Orn_Arg_deC_N PF02784.16 AAG08662.1 - 1.3e-80 270.4 0.0 1.6e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAG08662.1 - 5.2e-27 94.0 0.0 6.1e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AAG08662.1 - 1e-08 35.1 0.1 2.5e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain DAP_epimerase PF01678.19 AAG08663.1 - 7.3e-63 210.1 0.0 4e-33 114.2 0.0 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 AAG08663.1 - 2.2e-05 24.1 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF484 PF04340.12 AAG08664.1 - 1.4e-87 293.1 0.1 1.6e-87 292.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF484 NAD_binding_3 PF03447.16 AAG08664.1 - 0.16 12.6 0.1 0.26 11.9 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Phage_integrase PF00589.22 AAG08665.1 - 1.1e-43 149.1 0.1 1.2e-42 145.7 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAG08665.1 - 3.9e-23 81.5 3.5 3.9e-23 81.5 3.5 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAG08665.1 - 0.0014 19.0 0.2 0.045 14.2 0.2 2.4 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain HAD_2 PF13419.6 AAG08666.1 - 3.1e-21 76.2 0.0 1.9e-20 73.7 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG08666.1 - 5.1e-13 49.8 0.1 3.4e-12 47.1 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAG08666.1 - 8.8e-10 38.5 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAG08666.1 - 2.4e-05 24.8 1.2 5.1e-05 23.8 1.2 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 AAG08666.1 - 0.035 14.0 0.1 0.071 13.0 0.1 1.5 1 0 0 1 1 1 0 Acid Phosphatase MFS_1 PF07690.16 AAG08667.1 - 1.2e-17 63.9 62.1 4.8e-17 61.9 49.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG08667.1 - 2.9e-08 33.0 7.5 2.9e-08 33.0 7.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 AAG08667.1 - 0.0001 20.9 3.5 0.0001 20.9 3.5 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 AAG08667.1 - 0.0059 15.5 5.9 0.0059 15.5 5.9 2.6 3 0 0 3 3 3 2 MFS_1 like family OATP PF03137.20 AAG08667.1 - 0.029 12.6 1.1 0.063 11.6 1.1 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Aminotran_1_2 PF00155.21 AAG08668.1 - 7.5e-39 133.9 0.0 9.3e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AAG08668.1 - 2.8e-13 49.5 0.0 4.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase GntR PF00392.21 AAG08668.1 - 6.4e-13 48.1 1.0 1.8e-12 46.7 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAG08668.1 - 0.002 18.0 0.5 0.0078 16.1 0.2 2.1 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 AAG08668.1 - 0.085 12.7 0.7 2.1 8.2 0.1 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain Fimbrial PF00419.20 AAG08669.1 - 2e-12 47.6 0.3 3e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 Fimbrial protein UPF0047 PF01894.17 AAG08671.1 - 6.7e-35 119.7 0.0 7.7e-35 119.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Ammonium_transp PF00909.21 AAG08672.1 - 1.3e-117 393.0 44.1 1.4e-117 392.8 44.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SpoV PF08183.11 AAG08672.1 - 2 8.5 6.6 4.7 7.2 0.7 3.4 3 0 0 3 3 3 0 Stage V sporulation protein family P-II PF00543.22 AAG08673.1 - 4.6e-43 146.0 2.4 5.2e-43 145.8 2.4 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 AAG08673.1 - 0.002 18.3 0.0 0.0025 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3240) Cdc6_C PF09079.11 AAG08673.1 - 0.033 14.2 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain ChaC PF04752.12 AAG08673.1 - 0.039 14.0 0.0 0.048 13.7 0.0 1.0 1 0 0 1 1 1 0 ChaC-like protein DUF2344 PF10105.9 AAG08673.1 - 0.067 13.0 0.0 0.092 12.6 0.0 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) BMFP PF04380.13 AAG08674.1 - 4.9e-25 87.8 2.3 5.8e-25 87.6 2.3 1.0 1 0 0 1 1 1 1 Membrane fusogenic activity DUF4423 PF14394.6 AAG08674.1 - 0.029 14.1 0.2 0.036 13.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Phasin PF05597.11 AAG08674.1 - 0.045 13.8 0.7 0.24 11.4 0.6 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HrpB2 PF09487.10 AAG08674.1 - 0.076 13.4 0.6 0.1 13.0 0.5 1.3 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Mg_chelatase PF01078.21 AAG08675.1 - 3.8e-96 320.4 0.0 5.7e-96 319.8 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 AAG08675.1 - 1.1e-43 147.9 0.1 2.2e-43 147.0 0.0 1.5 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 AAG08675.1 - 4.9e-26 91.2 9.8 1.2e-25 89.9 9.8 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_5 PF07728.14 AAG08675.1 - 1.3e-10 41.4 0.0 1.1e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAG08675.1 - 7.4e-09 35.0 0.0 1e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 AAG08675.1 - 1.3e-06 28.2 0.0 0.0064 16.2 0.0 2.6 3 0 0 3 3 3 2 Sigma-54 interaction domain RuvB_N PF05496.12 AAG08675.1 - 0.00021 21.1 0.0 0.52 10.0 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain Lon_C PF05362.13 AAG08675.1 - 0.00064 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 AAG08675.1 - 0.00078 19.9 0.1 0.0032 17.9 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAG08675.1 - 0.0063 16.9 3.6 0.0068 16.8 0.0 2.7 4 0 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 AAG08675.1 - 0.019 15.2 0.0 0.047 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.6 AAG08675.1 - 0.023 13.5 0.2 5.9 5.6 0.5 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAG08675.1 - 0.065 13.0 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 AAG08675.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_lid_5 PF17865.1 AAG08675.1 - 0.18 11.9 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 Midasin AAA lid domain AAA_24 PF13479.6 AAG08675.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAG08675.1 - 0.2 12.0 0.1 0.68 10.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 AAG08675.1 - 0.27 10.7 0.0 0.56 9.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region BCCT PF02028.17 AAG08676.1 - 4.4e-200 665.2 40.7 5.1e-200 665.0 40.7 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter HAD PF12710.7 AAG08677.1 - 8.8e-05 23.0 0.1 0.0019 18.6 0.1 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG08677.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase LysR_substrate PF03466.20 AAG08678.1 - 8.1e-34 116.8 5.8 1.3e-33 116.2 5.8 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08678.1 - 2e-22 78.9 2.4 4.5e-22 77.8 2.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAG08678.1 - 0.009 16.1 0.1 0.03 14.4 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAG08678.1 - 0.0096 15.7 3.9 0.0099 15.7 0.9 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AAG08678.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAG08678.1 - 0.055 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAG08678.1 - 0.12 12.5 0.3 0.12 12.5 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MatE PF01554.18 AAG08679.1 - 1.7e-51 174.1 29.6 3.1e-30 105.0 6.3 2.7 3 0 0 3 3 3 2 MatE EAL PF00563.20 AAG08680.1 - 3.8e-73 245.9 0.1 6.6e-73 245.1 0.1 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAG08680.1 - 3e-32 111.6 0.0 5.5e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain UvrD-helicase PF00580.21 AAG08681.1 - 1.5e-74 251.3 2.6 3.8e-73 246.7 1.2 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AAG08681.1 - 6.1e-67 226.5 1.0 1.9e-66 224.9 1.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AAG08681.1 - 2.1e-33 115.7 0.0 4.3e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAG08681.1 - 3.4e-09 36.4 0.0 1.4e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AAG08681.1 - 5.4e-09 36.0 0.1 3.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAG08681.1 - 5.9e-06 26.2 0.3 0.082 12.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 AAG08681.1 - 0.0007 19.3 0.7 0.099 12.3 0.1 2.7 2 1 0 3 3 3 1 AAA domain DUF287 PF03384.14 AAG08681.1 - 0.16 12.4 1.3 0.28 11.6 0.2 2.0 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 TPP_enzyme_N PF02776.18 AAG08682.1 - 2.1e-44 151.1 4.6 2.9e-41 140.9 2.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAG08682.1 - 1e-37 129.3 0.1 1.8e-36 125.2 0.0 2.6 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAG08682.1 - 1.8e-32 112.0 0.0 4e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AAG08682.1 - 0.015 15.0 0.2 0.029 14.1 0.2 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg BCL9 PF11502.8 AAG08682.1 - 0.16 11.8 1.8 0.33 10.8 1.8 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Pribosyltran PF00156.27 AAG08683.1 - 3.1e-08 33.3 0.2 6.4e-08 32.3 0.2 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AcetylCoA_hyd_C PF13336.6 AAG08684.1 - 1.1e-44 152.1 0.0 1.5e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cytochrome_CBB3 PF13442.6 AAG08685.1 - 1.4e-13 50.9 0.6 2.1e-13 50.4 0.6 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DnaJ_CXXCXGXG PF00684.19 AAG08685.1 - 2.2 8.7 10.4 4.4 7.8 7.4 2.5 2 1 0 2 2 2 0 DnaJ central domain Cupin_2 PF07883.11 AAG08686.1 - 7.3e-20 70.5 0.0 1.2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 AAG08686.1 - 3.1e-15 56.0 0.1 1.5e-13 50.6 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 AAG08686.1 - 4.7e-11 42.6 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAG08686.1 - 6.3e-09 36.1 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAG08686.1 - 0.00039 19.9 0.4 0.0014 18.1 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_37 PF13744.6 AAG08686.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_3 PF05899.12 AAG08686.1 - 0.0014 18.3 0.1 0.086 12.5 0.2 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 AAG08686.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase HTH_38 PF13936.6 AAG08686.1 - 0.0034 17.1 0.2 0.006 16.3 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAG08686.1 - 0.0069 15.9 0.2 0.03 13.9 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAG08686.1 - 0.013 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_26 PF13443.6 AAG08686.1 - 0.016 15.6 0.3 0.03 14.8 0.3 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 AAG08686.1 - 0.016 15.0 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain CENP-B_N PF04218.13 AAG08686.1 - 0.03 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain LacI PF00356.21 AAG08686.1 - 0.048 13.5 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_25 PF13413.6 AAG08686.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAG08686.1 - 0.097 12.5 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_psq PF05225.16 AAG08686.1 - 0.1 12.4 1.0 0.3 10.8 0.0 2.3 3 0 0 3 3 3 0 helix-turn-helix, Psq domain CENP-C_C PF11699.8 AAG08686.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 2 0 0 2 2 1 0 Mif2/CENP-C like Ala_racemase_N PF01168.20 AAG08687.1 - 5.3e-71 238.8 0.1 6.4e-71 238.5 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 AAG08687.1 - 3.8e-40 136.5 0.0 6e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Ribonuc_L-PSP PF01042.21 AAG08688.1 - 7.6e-25 87.3 0.1 8.8e-25 87.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GATase_6 PF13522.6 AAG08688.1 - 0.072 13.3 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase domain Phage_Orf51 PF06194.11 AAG08688.1 - 0.1 12.6 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Phage Conserved Open Reading Frame 51 DAO PF01266.24 AAG08689.1 - 9.5e-71 239.2 0.2 1.1e-70 239.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG08689.1 - 3.3e-07 30.4 0.2 2.4e-05 24.5 0.1 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAG08689.1 - 1.6e-06 27.5 0.1 0.004 16.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAG08689.1 - 3.8e-06 27.4 0.1 0.001 19.6 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAG08689.1 - 1.4e-05 24.4 0.7 0.00077 18.6 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain ApbA PF02558.16 AAG08689.1 - 0.00011 21.9 0.2 0.00037 20.2 0.1 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAG08689.1 - 0.0002 21.3 0.1 0.00036 20.5 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAG08689.1 - 0.00056 19.5 0.2 0.0014 18.3 0.1 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 AAG08689.1 - 0.001 18.4 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 AAG08689.1 - 0.0022 17.3 0.1 0.0039 16.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAG08689.1 - 0.0094 15.3 1.0 0.12 11.7 1.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAG08689.1 - 0.031 13.6 0.4 0.051 12.9 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 AAG08689.1 - 0.033 14.7 0.0 0.088 13.3 0.0 1.9 1 1 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 AAG08689.1 - 0.038 13.3 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 AAG08689.1 - 0.04 13.0 0.0 0.31 10.1 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 AAG08689.1 - 0.066 12.4 0.1 0.28 10.4 0.1 1.9 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 AAG08689.1 - 0.068 12.5 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 AAG08689.1 - 0.073 11.8 0.0 6.1 5.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.25 AAG08689.1 - 0.082 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 AAG08689.1 - 0.099 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 AAG08689.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1318 PF07027.12 AAG08690.1 - 2.2e-26 92.1 5.2 2.6e-26 91.9 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1318) Lipoprotein_19 PF13617.6 AAG08691.1 - 1.1e-17 63.5 3.4 1.3e-17 63.3 3.4 1.1 1 0 0 1 1 1 1 YnbE-like lipoprotein DctA-YdbH PF11739.8 AAG08692.1 - 2.5e-60 203.7 0.1 7.3e-60 202.2 0.0 1.9 2 0 0 2 2 2 1 Dicarboxylate transport YukD PF08817.10 AAG08692.1 - 0.57 10.9 6.2 4.9 7.9 0.1 3.7 3 1 1 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD AsnC_trans_reg PF01037.21 AAG08693.1 - 1.6e-20 72.8 0.0 2.7e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAG08693.1 - 1.1e-19 69.8 0.5 1.7e-19 69.1 0.5 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAG08693.1 - 1.6e-19 69.4 0.2 2.7e-19 68.7 0.2 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 AAG08693.1 - 2.9e-07 30.3 0.0 5.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAG08693.1 - 0.00078 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAG08693.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.21 AAG08693.1 - 0.0084 15.7 0.1 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 AAG08693.1 - 0.0097 16.1 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.6 AAG08693.1 - 0.017 15.6 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Sigma70_r4 PF04545.16 AAG08693.1 - 0.033 13.7 1.2 0.1 12.2 1.2 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_11 PF08279.12 AAG08693.1 - 0.041 13.8 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain DDRGK PF09756.9 AAG08693.1 - 0.042 13.4 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain HTH_Crp_2 PF13545.6 AAG08693.1 - 0.066 13.2 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain LexA_DNA_bind PF01726.16 AAG08693.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain TrmB PF01978.19 AAG08693.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DAO PF01266.24 AAG08694.1 - 2.7e-56 191.7 1.8 3.1e-56 191.5 1.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAG08694.1 - 1.4e-06 27.8 0.0 8.5e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG08694.1 - 2e-06 27.9 0.6 7.5e-06 26.1 0.6 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAG08694.1 - 8.8e-05 21.9 0.2 0.00019 20.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAG08694.1 - 0.00023 20.6 2.0 0.00023 20.6 2.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAG08694.1 - 0.00023 20.5 0.0 0.003 16.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG08694.1 - 0.00026 20.3 1.0 0.00042 19.6 1.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 AAG08694.1 - 0.00026 20.2 0.9 0.00042 19.5 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAG08694.1 - 0.00031 19.9 1.1 0.0005 19.3 1.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 AAG08694.1 - 0.0012 17.6 0.5 0.0089 14.8 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 AAG08694.1 - 0.015 15.8 0.5 0.061 13.9 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAG08694.1 - 0.024 13.9 0.8 2.6 7.2 0.1 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAG08694.1 - 0.058 13.0 0.2 0.093 12.3 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 AAG08694.1 - 0.091 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 AAG08694.1 - 0.22 10.4 0.3 0.29 10.0 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 AAG08694.1 - 1.3 9.0 4.7 0.19 11.7 0.3 1.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding PLDc_2 PF13091.6 AAG08695.1 - 2.6e-43 147.1 0.0 1.5e-20 73.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAG08695.1 - 2e-09 37.2 0.1 0.00042 20.4 0.0 3.4 3 0 0 3 3 3 2 Phospholipase D Active site motif LPAM_1 PF08139.12 AAG08695.1 - 8.8 7.0 6.2 19 6.0 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site MFS_1 PF07690.16 AAG08696.1 - 4.2e-25 88.4 56.7 1.6e-14 53.6 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAG08696.1 - 7.7e-09 35.3 33.8 1e-08 34.9 33.8 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AAG08696.1 - 1.4e-05 24.2 11.5 1.4e-05 24.2 11.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 AAG08696.1 - 5.7e-05 22.2 8.2 5.7e-05 22.2 8.2 2.0 2 0 0 2 2 2 1 MFS_1 like family Aldedh PF00171.22 AAG08697.1 - 1.8e-170 567.4 0.1 2.1e-170 567.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAG08697.1 - 0.038 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) YCII PF03795.14 AAG08697.1 - 1.5 9.3 6.3 1.8 9.0 0.2 3.4 4 1 0 4 4 4 0 YCII-related domain Aminotran_3 PF00202.21 AAG08698.1 - 2.2e-89 299.9 0.0 2.6e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAG08698.1 - 0.0029 16.9 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AAG08698.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Cupin_3 PF05899.12 AAG08699.1 - 2.4e-23 81.6 0.4 3.3e-23 81.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 AAG08699.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Ppnp PF06865.11 AAG08699.1 - 0.049 14.1 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase Cupin_2 PF07883.11 AAG08699.1 - 0.072 12.8 0.3 0.14 11.9 0.1 1.6 2 0 0 2 2 2 0 Cupin domain DUF2793 PF10983.8 AAG08699.1 - 0.092 12.6 0.1 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) Ribosomal_L33 PF00471.20 AAG08700.1 - 3.6e-17 62.5 0.2 3.9e-17 62.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Ribosomal_L28 PF00830.19 AAG08701.1 - 1.1e-28 99.1 1.6 1.3e-28 98.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L28 family SBP_bac_5 PF00496.22 AAG08702.1 - 2.6e-87 293.3 0.0 3.1e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF2867 PF11066.8 AAG08703.1 - 0.0076 16.6 0.1 0.01 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) Glyco_transf_64 PF09258.10 AAG08703.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain RadC PF04002.15 AAG08704.1 - 5.1e-43 145.9 0.0 7.2e-43 145.4 0.0 1.1 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 AAG08704.1 - 9.2e-05 22.2 0.1 0.00015 21.5 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TrkA_TMD PF18613.1 AAG08704.1 - 0.38 10.2 1.5 0.81 9.2 1.5 1.5 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain DFP PF04127.15 AAG08705.1 - 1.4e-72 243.5 0.2 1.3e-71 240.2 0.0 2.1 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AAG08705.1 - 5.4e-42 143.2 0.0 8e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Glyco_trans_4_4 PF13579.6 AAG08705.1 - 0.00024 21.6 11.9 0.0055 17.2 0.4 3.0 2 1 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAG08705.1 - 0.029 14.3 0.2 11 5.9 0.0 2.8 3 0 0 3 3 3 0 Glycosyltransferase Family 4 PspC PF04024.12 AAG08705.1 - 0.21 11.4 0.4 0.46 10.3 0.4 1.5 1 0 0 1 1 1 0 PspC domain dUTPase PF00692.19 AAG08706.1 - 5e-40 136.2 0.0 5.6e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 dUTPase PGM_PMM_I PF02878.16 AAG08707.1 - 3e-37 127.4 0.0 4.8e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AAG08707.1 - 1.5e-28 99.5 0.1 2.9e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AAG08707.1 - 1.4e-21 76.9 0.0 2.4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AAG08707.1 - 5.3e-14 52.2 0.1 1.1e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2218 PF09981.9 AAG08707.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) AA_kinase PF00696.28 AAG08708.1 - 6.9e-44 150.3 5.0 8.3e-44 150.0 5.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family XPG_N PF00752.17 AAG08708.1 - 0.079 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 XPG N-terminal domain Arabinose_bd PF12625.7 AAG08709.1 - 3.7e-36 125.0 1.1 3.7e-36 125.0 1.1 1.7 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAG08709.1 - 1.7e-19 69.9 0.6 3.8e-19 68.7 0.6 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG08709.1 - 2e-10 40.5 0.0 2.2e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAG08709.1 - 1.3e-05 24.8 1.9 0.054 13.3 0.3 2.7 1 1 1 2 2 2 2 Homeodomain-like domain SurA_N PF09312.11 AAG08709.1 - 0.00076 19.5 0.2 0.0015 18.6 0.2 1.5 1 0 0 1 1 1 1 SurA N-terminal domain Sigma70_r4_2 PF08281.12 AAG08709.1 - 0.032 13.9 0.5 1.4 8.6 0.0 3.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_8 PF02954.19 AAG08709.1 - 0.034 13.9 0.1 0.12 12.2 0.1 2.0 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family DHR10 PF18595.1 AAG08709.1 - 0.065 13.3 0.7 0.1 12.6 0.7 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Phenol_MetA_deg PF13557.6 AAG08710.1 - 6.8e-58 196.5 1.1 8.4e-58 196.2 1.1 1.1 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation BBP2 PF07642.11 AAG08710.1 - 9.8e-05 21.6 0.7 0.00017 20.9 0.3 1.6 2 0 0 2 2 2 1 Putative beta-barrel porin-2, OmpL-like. bbp2 KdgM PF06178.13 AAG08710.1 - 0.067 12.8 3.4 0.11 12.1 3.4 1.2 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) Ala_racemase_N PF01168.20 AAG08711.1 - 4e-25 88.8 0.0 5.1e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain ALO PF04030.14 AAG08712.1 - 2.7e-68 230.6 0.1 3.5e-68 230.3 0.1 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 AAG08712.1 - 1.3e-22 80.1 0.2 2.5e-22 79.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Cytochrome_CBB3 PF13442.6 AAG08713.1 - 4.4e-15 55.7 0.2 5.4e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III COMM_domain PF07258.14 AAG08713.1 - 0.16 12.1 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 COMM domain 4HBT PF03061.22 AAG08714.1 - 1.9e-19 69.8 0.0 2.8e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAG08714.1 - 1.1e-10 42.1 0.0 1.3e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF1897 PF09005.10 AAG08714.1 - 0.027 13.9 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) DUF4124 PF13511.6 AAG08715.1 - 0.00096 19.4 1.0 0.0023 18.2 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) betaPIX_CC PF16523.5 AAG08715.1 - 0.0039 17.0 0.4 0.0039 17.0 0.4 1.7 2 0 0 2 2 2 1 betaPIX coiled coil FUSC PF04632.12 AAG08715.1 - 0.011 14.3 9.1 0.014 14.0 9.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family JIP_LZII PF16471.5 AAG08715.1 - 0.049 13.8 0.8 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 AAG08715.1 - 1.3 9.5 13.5 78 3.8 13.5 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Pribosyltran PF00156.27 AAG08716.1 - 4.4e-12 45.8 0.1 7.1e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PA PF02225.22 AAG08716.1 - 0.017 15.1 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 PA domain PRTase_2 PF15609.6 AAG08716.1 - 0.034 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Exo_endo_phos PF03372.23 AAG08717.1 - 1.9e-10 40.7 0.4 2.3e-10 40.4 0.4 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CbiK PF06180.11 AAG08717.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DUF4870 PF09685.10 AAG08718.1 - 5.2e-40 136.0 3.9 5.9e-40 135.8 3.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) TraL PF07178.11 AAG08718.1 - 0.025 15.0 2.5 0.032 14.7 0.9 1.8 2 0 0 2 2 2 0 TraL protein Claudin_2 PF13903.6 AAG08718.1 - 0.63 9.8 8.4 0.96 9.2 4.6 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RNase_PH PF01138.21 AAG08719.1 - 2.5e-27 96.0 0.0 3.8e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AAG08719.1 - 2.4e-10 40.3 0.0 5e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 YicC_N PF03755.13 AAG08720.1 - 4.6e-40 137.5 0.1 1.1e-39 136.3 0.0 1.7 2 1 0 2 2 2 1 YicC-like family, N-terminal region DUF1732 PF08340.11 AAG08720.1 - 1.7e-34 117.6 1.1 3e-34 116.9 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1732) Baculo_PEP_C PF04513.12 AAG08720.1 - 0.036 14.1 1.6 0.53 10.3 0.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1995 PF09353.10 AAG08720.1 - 0.66 10.0 5.2 1.2 9.1 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1995) Guanylate_kin PF00625.21 AAG08721.1 - 3.3e-54 183.4 0.0 3.8e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 AAG08721.1 - 1.3e-06 28.6 0.0 2.5e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAG08721.1 - 0.00024 21.6 0.0 0.00058 20.4 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 AAG08721.1 - 0.00045 20.5 0.7 0.006 16.9 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG08721.1 - 0.002 18.5 2.0 0.0071 16.7 2.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAG08721.1 - 0.027 14.9 0.2 0.19 12.1 0.1 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAG08721.1 - 0.047 13.6 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 AAG08721.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 AAG08721.1 - 0.064 13.3 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_35 PF14516.6 AAG08721.1 - 0.11 11.3 0.1 0.59 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.27 AAG08721.1 - 0.12 12.9 0.1 0.21 12.1 0.1 1.8 1 1 0 1 1 1 0 ABC transporter RNA_pol_Rpb6 PF01192.22 AAG08722.1 - 3.6e-17 62.0 0.0 4.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 HD_4 PF13328.6 AAG08723.1 - 5.9e-52 175.5 3.5 1.7e-51 174.1 3.5 1.8 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AAG08723.1 - 1.5e-37 128.4 0.1 3.4e-37 127.3 0.1 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 AAG08723.1 - 1.9e-19 69.5 0.0 4.4e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AAG08723.1 - 5.9e-16 58.8 2.5 1.8e-15 57.3 2.5 1.8 1 0 0 1 1 1 1 ACT domain HD PF01966.22 AAG08723.1 - 2.5e-10 40.6 1.0 9.4e-10 38.8 1.0 2.1 1 0 0 1 1 1 1 HD domain Ribonuc_L-PSP PF01042.21 AAG08724.1 - 4.8e-43 146.0 0.2 5.4e-43 145.8 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 AAG08724.1 - 0.012 15.8 0.0 0.016 15.3 0.0 1.2 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease LPAM_1 PF08139.12 AAG08725.1 - 0.0093 16.4 2.9 0.018 15.5 2.9 1.5 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site DUF4995 PF16386.5 AAG08725.1 - 0.042 13.8 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function LysE PF01810.18 AAG08726.1 - 6.5e-19 68.1 8.0 7.6e-19 67.9 8.0 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAG08726.1 - 0.00062 19.5 1.1 0.0016 18.2 1.0 1.8 1 1 0 1 1 1 1 Integral membrane protein TerC family AraC_binding PF02311.19 AAG08727.1 - 2.1e-25 89.2 0.6 2.1e-25 89.2 0.6 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain HTH_18 PF12833.7 AAG08727.1 - 3.4e-21 75.3 3.8 4e-21 75.1 2.8 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAG08727.1 - 4.9e-15 55.2 0.0 6.8e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAG08727.1 - 0.0011 18.6 0.2 0.0018 17.9 0.2 1.3 1 0 0 1 1 1 1 Cupin domain HTH_32 PF13565.6 AAG08727.1 - 0.074 13.7 2.2 0.31 11.7 2.1 2.2 1 1 0 1 1 1 0 Homeodomain-like domain Epimerase PF01370.21 AAG08728.1 - 4e-08 33.0 0.0 7.6e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAG08728.1 - 1.2e-05 25.2 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF4777 PF16007.5 AAG08728.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) LysR_substrate PF03466.20 AAG08729.1 - 5.5e-44 150.0 0.6 8.2e-44 149.5 0.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08729.1 - 9.6e-18 63.9 0.1 1.6e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAG08729.1 - 0.0071 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 MarR family DEAD PF00270.29 AAG08730.1 - 1.7e-18 67.0 0.0 9.7e-18 64.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAG08730.1 - 1.2e-17 64.3 0.0 7.1e-16 58.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecG_wedge PF17191.4 AAG08730.1 - 8.1e-15 54.8 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 RecG wedge domain ResIII PF04851.15 AAG08730.1 - 1.1e-08 35.2 0.0 2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 AAG08730.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain AAA_30 PF13604.6 AAG08730.1 - 2.3e-05 24.2 0.4 5.2e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 AAG08730.1 - 0.038 14.6 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Helicase_RecD PF05127.14 AAG08730.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Helicase AAA_22 PF13401.6 AAG08730.1 - 0.072 13.4 0.2 1.9 8.8 0.1 3.1 2 2 1 3 3 3 0 AAA domain DUF2075 PF09848.9 AAG08730.1 - 0.093 12.0 0.3 0.18 11.0 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol_lambd_f PF10391.9 AAG08730.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda SNF2_N PF00176.23 AAG08730.1 - 0.14 10.9 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SecA_DEAD PF07517.14 AAG08730.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Cdd1 PF11731.8 AAG08730.1 - 0.16 12.2 0.1 0.9 9.8 0.0 2.2 3 0 0 3 3 3 0 Pathogenicity locus HDOD PF08668.12 AAG08731.1 - 1.4e-45 155.2 0.0 2.6e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 HDOD domain tRNA_edit PF04073.15 AAG08731.1 - 1.7e-16 60.4 0.0 3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain KORA PF16509.5 AAG08731.1 - 0.044 14.1 0.0 4.5 7.6 0.0 2.5 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor SAM_3 PF18016.1 AAG08731.1 - 0.045 13.6 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Metallophos_C PF14008.6 AAG08732.1 - 0.034 15.0 0.0 0.053 14.4 0.0 1.3 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C Bac_DNA_binding PF00216.21 AAG08733.1 - 1.1e-32 112.1 0.1 1.2e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAG08733.1 - 2.7e-06 27.5 0.0 2.8e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAG08733.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.3 2 0 0 2 2 2 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AAG08733.1 - 0.0013 18.8 0.0 0.0015 18.7 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_1 PF18174.1 AAG08733.1 - 0.0096 15.8 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 AAG08733.1 - 0.011 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 DNA_pol_E_B PF04042.16 AAG08733.1 - 0.19 11.1 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Pyr_redox_2 PF07992.14 AAG08734.1 - 3.9e-50 170.7 0.0 5e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rbx_binding PF18113.1 AAG08734.1 - 1.5e-25 88.7 0.1 2.8e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Rubredoxin binding C-terminal domain Pyr_redox PF00070.27 AAG08734.1 - 6.7e-13 49.0 0.0 5.1e-10 39.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAG08734.1 - 2.1e-05 24.3 1.8 0.26 10.8 0.0 3.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAG08734.1 - 6.2e-05 22.2 0.1 0.7 8.9 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 AAG08734.1 - 8.4e-05 22.0 0.0 0.00091 18.6 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 AAG08734.1 - 0.0093 16.0 0.1 0.086 12.8 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding ThiF PF00899.21 AAG08734.1 - 0.039 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family Rubredoxin PF00301.20 AAG08735.1 - 3.9e-23 81.2 2.4 4.4e-23 81.1 2.4 1.0 1 0 0 1 1 1 1 Rubredoxin ADK_lid PF05191.14 AAG08735.1 - 0.022 14.7 0.5 0.16 12.0 0.5 1.9 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-RanBP PF00641.18 AAG08735.1 - 0.026 13.8 4.4 1.6 8.1 0.5 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Rubredoxin_2 PF18073.1 AAG08735.1 - 0.027 14.2 3.3 2.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain OrfB_Zn_ribbon PF07282.11 AAG08735.1 - 0.048 13.6 0.2 10 6.1 0.0 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 AAG08735.1 - 0.078 13.0 2.2 0.98 9.4 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_10 PF10058.9 AAG08735.1 - 0.093 12.5 1.1 3.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_SprT PF17283.2 AAG08735.1 - 0.098 12.6 5.1 3.4 7.7 0.3 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-Sec23_Sec24 PF04810.15 AAG08735.1 - 0.16 12.1 1.7 3.4 7.8 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_3 PF13878.6 AAG08735.1 - 0.19 11.6 0.1 4.3 7.2 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Vps36-NZF-N PF16988.5 AAG08735.1 - 0.7 9.3 6.7 3.3 7.2 1.0 2.3 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PHD_4 PF16866.5 AAG08735.1 - 1.1 9.4 6.3 4.9 7.3 6.3 1.9 1 1 0 1 1 1 0 PHD-finger Rubredoxin PF00301.20 AAG08736.1 - 2.6e-23 81.8 3.5 2.9e-23 81.6 3.5 1.0 1 0 0 1 1 1 1 Rubredoxin Zn_ribbon_SprT PF17283.2 AAG08736.1 - 0.011 15.6 1.0 2.7 8.0 0.4 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-RanBP PF00641.18 AAG08736.1 - 0.021 14.2 5.4 0.89 8.9 0.4 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF1936 PF09151.10 AAG08736.1 - 0.025 14.5 0.3 0.048 13.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) ADK_lid PF05191.14 AAG08736.1 - 0.068 13.2 0.2 0.18 11.8 0.2 1.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-C2H2_3 PF13878.6 AAG08736.1 - 0.099 12.5 0.2 1.9 8.4 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Vps36-NZF-N PF16988.5 AAG08736.1 - 0.37 10.2 2.2 6.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PHD_4 PF16866.5 AAG08736.1 - 0.87 9.7 7.0 7.4 6.7 7.0 2.0 1 1 0 1 1 1 0 PHD-finger Haem_degrading PF03928.14 AAG08737.1 - 1.5e-29 102.5 1.0 1.6e-29 102.3 1.0 1.0 1 0 0 1 1 1 1 Haem-degrading GAF_2 PF13185.6 AAG08737.1 - 0.037 14.3 2.1 0.28 11.5 2.1 2.3 1 1 0 1 1 1 0 GAF domain Diacid_rec PF05651.13 AAG08737.1 - 0.055 13.1 0.2 0.096 12.4 0.2 1.4 1 0 0 1 1 1 0 Putative sugar diacid recognition PocR PF10114.9 AAG08737.1 - 0.22 11.3 0.0 0.84 9.4 0.0 1.7 2 0 0 2 2 2 0 Sensory domain found in PocR CCG PF02754.16 AAG08738.1 - 4e-29 100.7 3.7 1.2e-13 51.0 0.1 3.3 3 0 0 3 3 3 2 Cysteine-rich domain Fer4_7 PF12838.7 AAG08738.1 - 2.9e-12 47.0 4.6 6.9e-12 45.8 4.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAG08738.1 - 9.4e-12 45.2 4.4 2.8e-11 43.7 4.4 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG08738.1 - 5.3e-10 39.7 5.4 1.2e-09 38.5 5.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAG08738.1 - 2.1e-06 27.6 10.5 0.0029 17.6 2.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 AAG08738.1 - 2.2e-05 24.1 8.3 0.013 15.3 0.6 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAG08738.1 - 7.5e-05 22.8 8.7 0.021 15.0 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAG08738.1 - 8.9e-05 23.4 3.5 0.0002 22.2 3.5 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AAG08738.1 - 0.00019 21.5 14.4 0.0012 18.9 11.7 2.6 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAG08738.1 - 0.00019 21.3 14.0 0.03 14.4 3.3 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAG08738.1 - 0.00047 20.2 5.4 0.34 11.1 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAG08738.1 - 0.013 16.3 6.8 1.7 9.5 0.8 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAG08738.1 - 0.014 15.8 19.9 0.071 13.7 1.4 3.2 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AAG08738.1 - 0.018 15.3 5.9 0.96 9.7 0.4 2.3 1 1 0 2 2 2 0 4Fe-4S dicluster domain Barstar PF01337.18 AAG08738.1 - 0.05 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Fer4_13 PF13370.6 AAG08738.1 - 0.098 13.2 7.3 3.6 8.2 0.9 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_20 PF14691.6 AAG08738.1 - 0.26 11.1 7.9 0.46 10.3 0.2 2.4 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster FAD_binding_4 PF01565.23 AAG08739.1 - 3.9e-19 68.8 0.2 6.8e-19 68.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 AAG08739.1 - 0.00026 20.7 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD-oxidase_C PF02913.19 AAG08740.1 - 2.6e-73 246.7 0.1 3.3e-73 246.4 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAG08740.1 - 3.5e-36 124.0 0.9 5.9e-36 123.3 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain FCD PF07729.12 AAG08741.1 - 2.3e-26 92.7 14.4 4.1e-26 91.8 14.4 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAG08741.1 - 1.1e-16 60.2 0.5 2.9e-16 58.9 0.5 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FadR_C PF07840.12 AAG08741.1 - 0.0009 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 FadR C-terminal domain Metal_resist PF13801.6 AAG08741.1 - 0.012 15.7 4.8 0.012 15.7 4.8 2.5 3 1 0 3 3 3 0 Heavy-metal resistance HTH_11 PF08279.12 AAG08741.1 - 0.038 13.9 0.6 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 HTH domain HTH_5 PF01022.20 AAG08741.1 - 0.073 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family LexA_DNA_bind PF01726.16 AAG08741.1 - 0.078 12.8 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 LexA DNA binding domain Chor_lyase PF04345.13 AAG08742.1 - 6.4e-79 263.4 0.0 7.1e-79 263.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate lyase DUF98 PF01947.16 AAG08742.1 - 0.0024 17.9 0.0 0.0031 17.5 0.0 1.3 1 1 0 1 1 1 1 p-hydroxybenzoic acid synthase UbiA PF01040.18 AAG08743.1 - 8.3e-66 221.9 23.3 1e-65 221.5 23.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Lipoprotein_15 PF03640.15 AAG08744.1 - 7.4e-34 115.0 7.9 4e-19 67.9 1.8 2.1 2 0 0 2 2 2 2 Secreted repeat of unknown function Response_reg PF00072.24 AAG08745.1 - 1.2e-30 105.9 0.2 1.6e-30 105.5 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAG08745.1 - 1.5e-24 85.9 0.1 2.7e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal PhoR PF11808.8 AAG08746.1 - 1.3e-28 99.3 7.6 2.6e-28 98.3 7.6 1.6 1 0 0 1 1 1 1 Phosphate regulon sensor protein PhoR HATPase_c PF02518.26 AAG08746.1 - 3.6e-25 88.7 0.0 5.7e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG08746.1 - 1e-18 67.1 4.2 1.1e-18 67.0 0.4 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAG08746.1 - 2.3e-07 30.7 0.4 2.9e-05 24.0 0.0 2.6 2 0 0 2 2 2 1 PAS domain HATPase_c_2 PF13581.6 AAG08746.1 - 2.4e-06 27.5 0.0 7.1e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS PF00989.25 AAG08746.1 - 8.2e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAG08746.1 - 0.00034 20.8 0.0 0.0025 18.0 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 AAG08746.1 - 0.0095 16.1 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 AAG08746.1 - 0.044 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAG08746.1 - 0.086 13.1 0.1 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 PAS fold TMEM208_SND2 PF05620.11 AAG08746.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF21 PF01595.20 AAG08747.1 - 5.7e-51 172.7 0.1 9.4e-51 172.0 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AAG08747.1 - 3.3e-17 62.2 0.2 9.5e-17 60.8 0.2 1.8 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AAG08747.1 - 1.1e-16 61.0 0.3 9.8e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain Bac_rhodopsin PF01036.18 AAG08747.1 - 1.6 8.2 7.1 0.09 12.3 1.7 1.5 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein Peptidase_M23 PF01551.22 AAG08748.1 - 1.3e-24 86.2 0.7 2.2e-24 85.5 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M23 DUF4124 PF13511.6 AAG08748.1 - 1.8e-10 41.0 0.0 3.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) Apocytochr_F_C PF01333.19 AAG08748.1 - 0.0073 16.3 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Apocytochrome F, C-terminal Response_reg PF00072.24 AAG08749.1 - 3e-27 95.0 0.0 5.4e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain PhoU PF01895.19 AAG08750.1 - 1.7e-41 140.5 11.1 3.6e-22 78.6 3.3 2.2 2 0 0 2 2 2 2 PhoU domain ING PF12998.7 AAG08750.1 - 0.00069 20.2 2.5 0.0013 19.2 0.7 2.2 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding AAA_13 PF13166.6 AAG08750.1 - 0.032 12.9 0.5 0.038 12.6 0.5 1.1 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 AAG08750.1 - 0.034 14.2 1.1 0.62 10.1 0.6 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cob_adeno_trans PF01923.18 AAG08750.1 - 0.11 12.6 0.9 0.32 11.1 0.1 1.9 1 1 0 2 2 2 0 Cobalamin adenosyltransferase YojJ PF10372.9 AAG08750.1 - 0.31 11.2 3.3 2.3 8.4 0.2 3.0 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus POTRA_TamA_1 PF17243.2 AAG08750.1 - 0.38 10.9 1.8 17 5.6 0.1 2.7 2 0 0 2 2 2 0 POTRA domain TamA domain 1 Apolipoprotein PF01442.18 AAG08750.1 - 0.71 9.7 5.3 4.2 7.2 5.2 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ABC_tran PF00005.27 AAG08751.1 - 5.5e-30 104.7 0.0 7.3e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG08751.1 - 1.7e-09 37.9 0.2 0.0014 18.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG08751.1 - 2.8e-06 26.9 0.0 0.0031 17.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAG08751.1 - 0.0002 21.3 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAG08751.1 - 0.00026 21.3 0.0 0.00067 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG08751.1 - 0.00069 20.0 0.0 0.0011 19.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG08751.1 - 0.0012 18.5 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAG08751.1 - 0.0013 19.3 0.0 0.0028 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAG08751.1 - 0.0073 16.0 0.0 0.009 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAG08751.1 - 0.032 14.2 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 AAG08751.1 - 0.042 14.0 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAG08751.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAG08751.1 - 0.12 12.1 0.0 0.97 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 AAG08751.1 - 0.12 11.8 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 AAG08751.1 - 0.12 12.7 0.0 1 9.8 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 AAG08751.1 - 0.15 10.8 0.0 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class BPD_transp_1 PF00528.22 AAG08752.1 - 7e-18 65.0 11.4 7e-18 65.0 11.4 2.5 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAG08753.1 - 7.6e-12 45.3 23.1 1.3e-10 41.3 23.1 2.1 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component PBP_like_2 PF12849.7 AAG08754.1 - 1.3e-33 116.9 0.7 2e-33 116.3 0.7 1.2 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AAG08754.1 - 7.6e-11 41.5 0.0 1.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAG08754.1 - 2.6e-08 33.9 1.0 1.5e-06 28.2 0.2 2.8 1 1 1 2 2 2 2 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AAG08754.1 - 0.012 15.0 0.2 0.046 13.1 0.0 1.9 2 0 0 2 2 2 0 LysR substrate binding domain MFS_1 PF07690.16 AAG08755.1 - 4.5e-25 88.3 53.3 1.2e-19 70.5 29.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG08755.1 - 1.7e-20 73.3 5.2 1.7e-20 73.3 5.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter 4HBT PF03061.22 AAG08756.1 - 8.1e-16 58.2 0.1 1.1e-15 57.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily GMC_oxred_N PF00732.19 AAG08757.1 - 8.6e-96 320.8 0.0 1.2e-95 320.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AAG08757.1 - 8.1e-42 143.2 0.0 1.2e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 AAG08757.1 - 0.0027 16.8 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAG08757.1 - 0.0055 16.9 0.2 0.013 15.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAG08757.1 - 0.022 13.8 0.3 0.29 10.2 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 AAG08757.1 - 0.048 12.9 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG08757.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Aldedh PF00171.22 AAG08758.1 - 1.2e-181 604.3 0.1 1.3e-181 604.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TetR_C_6 PF13977.6 AAG08759.1 - 1.6e-34 118.5 4.0 1.6e-34 118.5 4.0 2.0 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 AAG08759.1 - 5.3e-10 38.9 0.1 1.1e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AAG08759.1 - 0.0034 17.6 1.8 0.0034 17.6 1.8 2.6 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_28 PF17937.1 AAG08759.1 - 0.14 12.6 10.6 0.082 13.4 4.9 2.9 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BCCT PF02028.17 AAG08760.1 - 1.6e-168 561.1 26.1 1.8e-168 560.9 26.1 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter ABC_tran PF00005.27 AAG08761.1 - 5.7e-28 98.1 0.0 9.6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG08761.1 - 2e-07 31.1 0.8 0.0031 17.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAG08761.1 - 0.00044 20.7 1.4 0.0031 17.9 1.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAG08761.1 - 0.0022 17.9 0.2 0.0048 16.8 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AAG08761.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CBS PF00571.28 AAG08761.1 - 0.067 13.7 0.1 0.24 11.9 0.1 2.0 2 0 0 2 2 2 0 CBS domain ABC_ATPase PF09818.9 AAG08761.1 - 0.092 11.5 0.1 0.44 9.3 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class BPD_transp_1 PF00528.22 AAG08762.1 - 1.1e-27 97.0 8.7 1.1e-27 97.0 8.7 2.1 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component DUF3464 PF11947.8 AAG08762.1 - 0.23 11.2 3.1 0.43 10.3 3.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 OpuAC PF04069.12 AAG08763.1 - 8.4e-64 215.6 0.3 1.1e-63 215.2 0.3 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Zn_ribbon_2 PF12674.7 AAG08763.1 - 0.083 13.6 0.0 0.26 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative zinc ribbon domain SDH_alpha PF03313.15 AAG08764.1 - 2e-103 345.6 3.6 2.6e-103 345.2 3.6 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 AAG08764.1 - 5.2e-55 186.1 0.0 1.1e-54 185.1 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain MmgE_PrpD PF03972.14 AAG08764.1 - 0.24 9.9 5.8 0.35 9.4 5.8 1.2 1 0 0 1 1 1 0 MmgE/PrpD family HTH_18 PF12833.7 AAG08765.1 - 6.6e-23 80.8 0.1 1.4e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AAG08765.1 - 7.3e-18 64.9 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 AAG08765.1 - 4.7e-14 52.1 0.0 3.6e-07 30.1 0.0 2.7 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family LysR_substrate PF03466.20 AAG08767.1 - 8.8e-50 169.0 3.8 1.3e-49 168.5 3.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08767.1 - 7e-18 64.3 2.9 1.4e-17 63.3 1.2 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAG08767.1 - 0.00041 19.5 0.0 0.0036 16.5 0.0 2.1 1 1 0 1 1 1 1 PBP superfamily domain PBP_like_2 PF12849.7 AAG08767.1 - 0.01 15.6 0.0 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 PBP superfamily domain NPR1_like_C PF12313.8 AAG08767.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Cons_hypoth698 PF03601.14 AAG08768.1 - 1.1e-115 385.8 17.2 1.2e-115 385.5 17.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 698 WBS28 PF15164.6 AAG08768.1 - 6.7 5.9 18.6 1.9 7.7 0.2 3.1 2 1 1 3 3 3 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Abhydrolase_3 PF07859.13 AAG08769.1 - 2.3e-65 220.4 0.1 3.1e-65 220.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 AAG08769.1 - 7.3e-05 21.8 0.0 9.8e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 AAG08769.1 - 0.0041 16.1 0.0 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 AAG08769.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family 4HBT_2 PF13279.6 AAG08770.1 - 1.3e-18 67.6 0.0 1.5e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAG08770.1 - 0.0002 21.7 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 3HCDH_N PF02737.18 AAG08771.1 - 8.1e-40 136.6 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AAG08771.1 - 2.1e-15 57.1 0.0 4.5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 AAG08771.1 - 0.032 13.6 0.0 0.084 12.2 0.0 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAG08771.1 - 0.069 13.3 0.0 0.35 11.0 0.0 2.2 3 1 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase BKACE PF05853.12 AAG08772.1 - 5.4e-97 324.4 0.0 6e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme OpuAC PF04069.12 AAG08773.1 - 2.8e-54 184.4 0.0 3.3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system HTH_18 PF12833.7 AAG08774.1 - 4.3e-22 78.2 1.1 1.1e-21 76.9 1.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AAG08774.1 - 6.8e-14 52.0 0.0 9.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 AAG08774.1 - 6.9e-11 42.0 0.1 1.1e-07 31.7 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Peptidase_M20 PF01546.28 AAG08775.1 - 4.5e-37 127.8 0.0 6.6e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAG08775.1 - 2.3e-25 88.6 0.0 3.4e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1028 PF06267.12 AAG08776.1 - 7.8e-69 231.3 1.0 9e-69 231.1 1.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF1028) Ribonuc_L-PSP PF01042.21 AAG08777.1 - 5.7e-22 78.0 0.0 7e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Spore_SspJ PF09575.10 AAG08777.1 - 0.032 14.6 0.1 0.056 13.8 0.1 1.4 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) Pyr_redox_3 PF13738.6 AAG08778.1 - 3.6e-29 102.0 0.0 4.4e-27 95.1 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAG08778.1 - 2.1e-12 46.9 0.0 4.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AAG08778.1 - 3.7e-11 42.8 0.0 1.4e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 AAG08778.1 - 1.6e-08 34.5 0.1 0.053 13.1 0.0 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAG08778.1 - 5e-08 32.6 1.1 0.00023 20.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FMO-like PF00743.19 AAG08778.1 - 7.8e-07 27.9 0.0 1.4e-05 23.7 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 AAG08778.1 - 3.7e-05 23.7 1.4 1.4 8.9 0.0 3.4 2 1 1 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 AAG08778.1 - 5.7e-05 22.4 0.1 0.67 9.0 0.0 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAG08778.1 - 6e-05 23.2 0.4 0.21 11.8 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAG08778.1 - 9.3e-05 22.9 0.2 0.11 13.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG08778.1 - 0.00029 19.7 1.2 2.9 6.5 0.6 3.1 3 0 0 3 3 3 2 HI0933-like protein ThiF PF00899.21 AAG08778.1 - 0.0003 20.3 0.0 0.29 10.5 0.0 2.3 2 0 0 2 2 2 2 ThiF family Lycopene_cycl PF05834.12 AAG08778.1 - 0.00075 18.7 0.3 0.5 9.4 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 AAG08778.1 - 0.0022 17.3 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Shikimate_DH PF01488.20 AAG08778.1 - 0.0024 18.0 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 AAG08778.1 - 0.011 16.0 0.1 3.3 8.0 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 AAG08778.1 - 0.016 14.9 0.1 0.49 10.0 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Malic_M PF03949.15 AAG08778.1 - 0.024 13.9 0.1 0.97 8.6 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 AAG08778.1 - 0.031 13.6 0.1 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 AAG08778.1 - 0.066 12.3 4.0 8.1 5.4 1.1 3.1 3 0 0 3 3 3 0 FAD binding domain DUF4147 PF13660.6 AAG08778.1 - 0.18 11.3 0.0 5.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) 3HCDH_N PF02737.18 AAG08778.1 - 0.19 11.6 0.2 3.2 7.6 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PLDc_2 PF13091.6 AAG08779.1 - 1.2e-37 128.8 0.0 8.4e-28 96.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAG08779.1 - 2.1e-13 49.8 0.3 2.5e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_N PF13396.6 AAG08779.1 - 3.8e-05 23.5 1.6 7e-05 22.7 1.6 1.5 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF2407 PF10302.9 AAG08779.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF1348 PF07080.11 AAG08780.1 - 1.7e-67 225.3 4.2 1.9e-67 225.1 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 AAG08780.1 - 7.2e-07 29.8 0.7 9.4e-07 29.4 0.7 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAG08780.1 - 7.2e-05 23.1 0.1 9.4e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Peptidase_M19 PF01244.21 AAG08781.1 - 8.3e-94 314.3 0.0 9.8e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) V4R PF02830.18 AAG08782.1 - 0.00016 21.6 0.1 0.0008 19.4 0.0 2.1 2 0 0 2 2 2 1 V4R domain Oxidored_FMN PF00724.20 AAG08783.1 - 1.7e-64 218.3 0.0 2.3e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AAG08783.1 - 2.5e-11 43.4 1.6 3.9e-10 39.4 1.6 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAG08783.1 - 3.4e-11 43.2 0.0 2.2e-09 37.4 0.1 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAG08783.1 - 7.6e-10 39.2 0.2 5.3e-07 30.1 0.2 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG08783.1 - 9.8e-10 38.3 0.5 1.7e-09 37.6 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAG08783.1 - 2.8e-08 32.9 0.6 4.4e-08 32.2 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AAG08783.1 - 1.4e-07 31.0 1.6 2.9e-07 29.9 1.2 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 AAG08783.1 - 4.7e-06 25.9 0.4 7.4e-06 25.3 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 AAG08783.1 - 2.3e-05 24.1 0.9 7e-05 22.6 0.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAG08783.1 - 5.1e-05 22.7 0.3 0.00011 21.6 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AAG08783.1 - 0.00014 21.2 0.1 0.00047 19.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 AAG08783.1 - 0.00014 21.2 0.1 0.0015 17.8 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 AAG08783.1 - 0.0013 18.1 0.1 0.0041 16.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 AAG08783.1 - 0.0073 16.7 0.0 0.033 14.6 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 AAG08783.1 - 0.01 15.2 0.1 0.022 14.0 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Peripla_BP_2 PF01497.18 AAG08783.1 - 0.015 14.9 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein 3HCDH_N PF02737.18 AAG08783.1 - 0.02 14.8 0.6 0.036 13.9 0.2 1.6 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 AAG08783.1 - 0.069 13.7 0.0 0.42 11.1 0.0 2.4 3 0 0 3 3 3 0 XdhC Rossmann domain Trp_halogenase PF04820.14 AAG08783.1 - 0.083 11.7 0.3 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 AAG08783.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 AAG08783.1 - 0.17 10.3 0.0 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like DUF3483 PF11982.8 AAG08784.1 - 9.6e-90 300.0 15.8 1.3e-89 299.6 15.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3483) CCG PF02754.16 AAG08784.1 - 1.6e-19 69.9 0.0 1.1e-13 51.2 0.0 2.5 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 AAG08784.1 - 3.5e-12 46.6 1.0 8.2e-12 45.4 1.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAG08784.1 - 5.5e-08 32.9 5.7 5.5e-08 32.9 5.7 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAG08784.1 - 1.1e-07 31.8 8.6 1.1e-07 31.8 8.6 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAG08784.1 - 8.5e-07 29.4 8.6 5.5e-06 26.8 6.9 2.8 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAG08784.1 - 3.3e-05 23.7 10.6 0.016 15.2 1.7 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAG08784.1 - 4.9e-05 23.5 15.5 0.014 15.8 1.8 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAG08784.1 - 0.00015 22.3 10.6 0.00015 22.3 10.6 2.3 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAG08784.1 - 0.00021 21.0 16.3 0.012 15.4 4.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAG08784.1 - 0.00057 20.8 10.2 0.071 14.0 1.0 2.6 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AAG08784.1 - 0.0016 18.4 15.7 0.069 13.3 4.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAG08784.1 - 0.017 15.3 4.9 0.15 12.2 0.1 2.5 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAG08784.1 - 0.018 15.1 10.9 0.39 10.9 0.7 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAG08784.1 - 0.39 11.6 8.3 0.35 11.8 0.3 3.1 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAG08784.1 - 0.85 10.2 12.2 4.8 7.8 1.9 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AAG08784.1 - 2.5 8.9 8.6 0.84 10.4 0.2 3.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain ETF_alpha PF00766.19 AAG08785.1 - 2.7e-24 85.0 1.1 7.9e-24 83.5 1.1 1.9 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 AAG08785.1 - 1.1e-16 61.3 0.0 1.9e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF PF01012.21 AAG08786.1 - 1.2e-16 61.1 0.4 2.4e-16 60.2 0.4 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF2975 PF11188.8 AAG08787.1 - 0.0038 17.1 2.0 0.0058 16.5 0.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2975) DUF4131 PF13567.6 AAG08787.1 - 0.96 9.1 6.3 1.4 8.5 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HTH_26 PF13443.6 AAG08788.1 - 2.3e-23 82.4 0.1 2.6e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 AAG08788.1 - 2.4e-07 30.7 0.0 3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 AAG08788.1 - 7.9e-05 22.5 0.0 9.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG08788.1 - 0.00035 20.5 0.0 0.00039 20.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain DUF739 PF05339.11 AAG08788.1 - 0.0093 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF739) HTH_31 PF13560.6 AAG08788.1 - 0.029 14.7 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF473 PF04322.12 AAG08788.1 - 0.042 13.7 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF473) YdaS_antitoxin PF15943.5 AAG08788.1 - 0.059 13.2 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF871 PF05913.11 AAG08788.1 - 0.13 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) GOLGA2L5 PF15070.6 AAG08789.1 - 0.071 11.8 1.9 0.085 11.5 1.9 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 ZapB PF06005.12 AAG08791.1 - 0.00016 22.1 18.4 0.00019 21.8 18.4 1.1 1 0 0 1 1 1 1 Cell division protein ZapB APG6_N PF17675.1 AAG08791.1 - 0.01 16.4 10.5 0.012 16.2 10.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1902 PF08972.11 AAG08791.1 - 0.038 14.0 2.3 0.062 13.3 1.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1902) FlaC_arch PF05377.11 AAG08791.1 - 0.041 14.3 3.7 0.059 13.8 2.4 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) GyrB_insert PF18053.1 AAG08791.1 - 0.047 13.6 5.8 0.062 13.2 5.5 1.4 1 1 0 1 1 1 0 DNA gyrase B subunit insert domain DivIVA PF05103.13 AAG08791.1 - 0.05 13.7 6.7 0.059 13.4 6.7 1.1 1 0 0 1 1 1 0 DivIVA protein CENP-H PF05837.12 AAG08791.1 - 0.099 13.1 10.9 0.12 12.8 10.9 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IFT57 PF10498.9 AAG08791.1 - 0.12 11.3 7.9 0.15 11.0 7.9 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Snapin_Pallidin PF14712.6 AAG08791.1 - 0.14 12.6 10.7 0.21 12.1 10.7 1.3 1 0 0 1 1 1 0 Snapin/Pallidin YabA PF06156.13 AAG08791.1 - 0.2 12.3 6.2 0.29 11.8 6.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Paralemmin PF03285.15 AAG08791.1 - 0.24 10.9 5.3 0.29 10.7 5.3 1.1 1 0 0 1 1 1 0 Paralemmin DUF2203 PF09969.9 AAG08791.1 - 0.76 10.5 5.5 1 10.1 5.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) bZIP_1 PF00170.21 AAG08791.1 - 0.78 9.9 8.6 0.2 11.8 3.4 2.3 1 1 2 3 3 3 0 bZIP transcription factor VPS11_C PF12451.8 AAG08791.1 - 1.3 9.3 5.8 0.81 10.0 3.9 1.6 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal FUSC PF04632.12 AAG08791.1 - 1.8 7.0 7.3 2 6.8 7.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rnk_N PF14760.6 AAG08791.1 - 1.9 9.0 7.3 12 6.5 0.1 2.8 2 1 0 2 2 2 0 Rnk N-terminus SlyX PF04102.12 AAG08791.1 - 2.1 9.0 18.9 3.8 8.2 10.6 2.1 1 1 1 2 2 2 0 SlyX ZapA PF05164.13 AAG08792.1 - 2.6e-13 50.2 0.3 8.1e-13 48.6 0.3 1.6 1 1 0 1 1 1 1 Cell division protein ZapA DUF308 PF03729.13 AAG08794.1 - 1.1e-29 102.5 54.3 6.5e-15 55.2 17.8 3.0 1 1 2 3 3 3 3 Short repeat of unknown function (DUF308) DUF4203 PF13886.6 AAG08794.1 - 0.00043 20.0 31.8 0.008 15.9 31.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) Ring_hydroxyl_A PF00848.19 AAG08795.1 - 7.8e-47 160.0 0.5 3.2e-46 158.0 0.3 1.9 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 AAG08795.1 - 9.5e-17 60.7 0.1 1.7e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_6 PF00970.24 AAG08796.1 - 3.2e-17 62.7 0.0 5.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AAG08796.1 - 1.7e-14 54.4 0.0 3.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AAG08796.1 - 8.5e-13 48.1 1.0 1.6e-12 47.2 1.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAG08796.1 - 6.7e-05 22.9 0.0 0.0003 20.8 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AAG08796.1 - 0.00054 20.1 0.1 0.0022 18.1 0.0 1.9 1 1 0 2 2 2 1 Ferric reductase NAD binding domain DHODB_Fe-S_bind PF10418.9 AAG08796.1 - 0.021 14.6 2.7 0.058 13.2 2.7 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Beta_elim_lyase PF01212.21 AAG08798.1 - 1.1e-79 267.8 0.0 1.3e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAG08798.1 - 0.0052 15.8 0.0 0.0091 15.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V LPAM_1 PF08139.12 AAG08799.1 - 0.22 12.1 0.4 0.79 10.3 0.4 2.0 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SHMT PF00464.19 AAG08800.1 - 1.9e-180 599.7 0.1 2.2e-180 599.5 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AAG08800.1 - 2.8e-06 26.7 0.0 3.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAG08800.1 - 6.4e-05 22.4 0.1 0.00019 20.8 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AAG08800.1 - 7.4e-05 21.4 0.0 0.00013 20.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAG08800.1 - 0.00099 18.5 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DAO PF01266.24 AAG08801.1 - 2e-55 188.8 3.2 2.3e-55 188.6 3.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAG08801.1 - 1.3e-06 28.6 0.1 1.3e-06 28.6 0.1 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAG08801.1 - 1.6e-06 27.5 4.0 0.00016 20.9 1.4 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 AAG08801.1 - 1.4e-05 24.5 0.2 2.7e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 AAG08801.1 - 0.00012 21.6 2.7 0.00051 19.5 2.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAG08801.1 - 0.0014 17.9 0.8 0.015 14.6 0.8 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAG08801.1 - 0.0026 17.1 0.1 0.0076 15.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG08801.1 - 0.0084 15.4 1.3 0.012 14.9 0.7 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AAG08801.1 - 0.032 14.8 1.9 1.9 9.1 1.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAG08801.1 - 0.061 12.0 1.2 3.1 6.4 0.5 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 AAG08801.1 - 0.11 12.4 0.7 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 AAG08801.1 - 0.15 10.8 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 AAG08801.1 - 0.28 10.0 3.8 0.12 11.3 1.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase SoxD PF04267.12 AAG08802.1 - 6.1e-37 125.6 0.7 7.1e-37 125.4 0.7 1.1 1 0 0 1 1 1 1 Sarcosine oxidase, delta subunit family zf-ribbon_3 PF13248.6 AAG08802.1 - 0.05 13.0 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain GCV_T PF01571.21 AAG08803.1 - 1.9e-75 253.6 0.2 2.8e-75 253.0 0.2 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SO_alpha_A3 PF17806.1 AAG08803.1 - 5.7e-32 109.9 0.0 1.2e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain Fer2_4 PF13510.6 AAG08803.1 - 2.1e-23 82.1 0.0 6.3e-23 80.6 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GCV_T_C PF08669.11 AAG08803.1 - 4.8e-20 71.3 0.0 1.7e-19 69.5 0.0 2.1 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 AAG08803.1 - 4e-12 46.0 0.2 7.7e-12 45.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAG08803.1 - 1.5e-10 41.0 1.4 2.6e-10 40.3 1.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG08803.1 - 4.2e-08 32.7 1.9 4.2e-08 32.7 1.9 2.7 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.22 AAG08803.1 - 1.2e-07 31.2 5.3 4.3e-06 26.1 0.3 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAG08803.1 - 1.3e-06 28.6 0.4 7.8e-06 26.0 0.2 2.5 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAG08803.1 - 1.8e-06 26.9 0.4 2.9e-06 26.3 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 AAG08803.1 - 6.2e-06 25.7 0.1 0.0082 15.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 AAG08803.1 - 6.8e-05 23.0 0.0 0.0013 18.9 0.0 2.5 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family FAD_binding_3 PF01494.19 AAG08803.1 - 7.4e-05 22.2 0.2 0.00014 21.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAG08803.1 - 0.00044 20.0 10.3 0.033 13.8 8.7 3.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAG08803.1 - 0.0006 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 AAG08803.1 - 0.00066 19.0 0.1 0.0015 17.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AAG08803.1 - 0.00072 20.1 0.2 0.1 13.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAG08803.1 - 0.027 13.5 1.1 0.12 11.4 1.1 2.2 1 0 0 1 1 1 0 Lycopene cyclase protein HATPase_c PF02518.26 AAG08803.1 - 0.081 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SoxG PF04268.12 AAG08804.1 - 2.8e-59 199.5 0.0 3.5e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family GCV_T PF01571.21 AAG08804.1 - 1e-08 34.9 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain KinB_sensor PF16767.5 AAG08804.1 - 0.068 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Formyl_trans_N PF00551.19 AAG08805.1 - 5.5e-36 124.0 0.0 6.8e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ADH_N PF08240.12 AAG08806.1 - 1.1e-26 92.8 2.8 1.8e-26 92.1 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAG08806.1 - 6.5e-07 29.4 0.7 1.4e-06 28.3 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAG08806.1 - 6e-06 25.7 0.5 1.1e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 AAG08806.1 - 0.00061 19.9 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAG08806.1 - 0.098 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 AAG08806.1 - 0.36 10.0 0.8 0.54 9.5 0.8 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldose_epim PF01263.20 AAG08807.1 - 2.6e-62 210.8 0.0 3e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3299 PF11736.8 AAG08808.1 - 8.1e-46 155.5 0.0 9.6e-46 155.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3299) Alpha-mann_mid PF09261.11 AAG08808.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.5 2 0 0 2 2 2 0 Alpha mannosidase middle domain Transgly_assoc PF04226.13 AAG08809.1 - 1.9e-12 47.3 19.4 3.3e-12 46.5 13.2 2.2 2 0 0 2 2 2 2 Transglycosylase associated protein FeoB_associated PF12669.7 AAG08809.1 - 0.12 12.8 8.1 1.3 9.5 1.6 2.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein FecCD PF01032.18 AAG08809.1 - 0.16 10.9 8.5 0.18 10.8 8.5 1.0 1 0 0 1 1 1 0 FecCD transport family 5TM-5TMR_LYT PF07694.12 AAG08809.1 - 0.6 9.6 12.9 1.2 8.7 12.9 1.4 1 1 0 1 1 1 0 5TMR of 5TMR-LYT Syndecan PF01034.20 AAG08809.1 - 2 8.4 5.6 4.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain DUF4064 PF13273.6 AAG08809.1 - 2.3 8.5 12.5 0.34 11.2 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ATP-grasp PF02222.22 AAG08810.1 - 1.6e-57 193.8 0.0 2.3e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AAG08810.1 - 9e-14 50.9 0.0 1.7e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain 2-Hacid_dh_C PF02826.19 AAG08810.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GARS_A PF01071.19 AAG08810.1 - 0.026 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 AAG08810.1 - 0.049 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain AIRC PF00731.20 AAG08811.1 - 4.7e-64 214.4 0.6 5.2e-64 214.3 0.6 1.0 1 0 0 1 1 1 1 AIR carboxylase TMEM52 PF14979.6 AAG08811.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 DUF2334 PF10096.9 AAG08811.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) ADH_N PF08240.12 AAG08812.1 - 1.8e-33 114.6 0.7 3.4e-33 113.8 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAG08812.1 - 4.8e-27 94.5 0.4 7.4e-27 93.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAG08812.1 - 0.00058 19.2 1.1 0.00094 18.5 1.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AAG08812.1 - 0.0087 16.3 0.8 0.014 15.7 0.8 1.3 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAG08812.1 - 0.044 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 AAG08812.1 - 0.12 13.1 0.1 0.25 12.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 AAG08812.1 - 0.13 11.8 0.8 0.2 11.2 0.8 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 AAG08812.1 - 0.21 11.5 0.2 0.32 10.9 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LysR_substrate PF03466.20 AAG08813.1 - 6.8e-29 100.7 0.9 6.8e-29 100.7 0.9 1.7 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08813.1 - 6.3e-18 64.5 0.5 6.3e-18 64.5 0.5 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Lyase_1 PF00206.20 AAG08814.1 - 3.5e-97 325.5 0.0 4.4e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AAG08814.1 - 1.1e-19 70.6 0.2 2.9e-19 69.2 0.2 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Sulf_transp PF04143.14 AAG08815.1 - 2.7e-80 270.2 37.3 2.7e-80 270.2 37.3 2.0 2 0 0 2 2 2 1 Sulphur transport GntR PF00392.21 AAG08816.1 - 3.3e-16 58.7 0.3 8.5e-16 57.4 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 AAG08816.1 - 9.5e-16 57.9 0.0 1.2e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_11 PF08279.12 AAG08816.1 - 0.00051 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AAG08816.1 - 0.00052 19.9 0.9 0.0012 18.8 0.2 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAG08816.1 - 0.0028 17.5 0.1 0.012 15.5 0.1 2.1 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.6 AAG08816.1 - 0.0039 17.1 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 AAG08816.1 - 0.021 15.1 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_6 PF01418.17 AAG08816.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_24 PF13412.6 AAG08816.1 - 0.051 13.1 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAG08816.1 - 0.17 11.8 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 AAG08816.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RPA_C PF08784.11 AAG08816.1 - 0.2 12.3 0.0 0.42 11.3 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Acetyltransf_1 PF00583.25 AAG08817.1 - 2e-13 50.6 0.1 2.4e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAG08817.1 - 1.4e-07 31.9 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAG08817.1 - 2.7e-07 30.6 0.0 3.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAG08817.1 - 0.00095 19.1 0.0 0.0015 18.4 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AAG08817.1 - 0.005 16.9 0.0 0.014 15.5 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 AAG08817.1 - 0.0067 16.1 0.1 0.011 15.5 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_8 PF13523.6 AAG08817.1 - 0.017 14.8 0.2 0.027 14.1 0.2 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAG08818.1 - 9.9e-12 45.7 0.0 2e-11 44.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG08818.1 - 5.1e-05 23.5 0.0 7.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AAG08818.1 - 0.053 13.7 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4880 PF16220.5 AAG08818.1 - 0.51 10.3 9.3 0.73 9.8 2.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Trp_Tyr_perm PF03222.13 AAG08819.1 - 3.1e-146 487.5 22.4 3.5e-146 487.3 22.4 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 AAG08819.1 - 0.0011 17.7 19.4 0.0012 17.6 17.2 2.3 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein PYC_OADA PF02436.18 AAG08820.1 - 2.8e-57 193.7 0.0 4.7e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 AAG08820.1 - 7.9e-51 173.1 0.1 1.2e-50 172.5 0.1 1.2 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 AAG08820.1 - 1.2e-18 66.6 3.9 2.6e-17 62.4 3.4 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAG08820.1 - 6.5e-12 45.1 1.2 2.7e-05 23.9 0.1 2.6 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 AAG08820.1 - 6.6e-05 22.8 1.5 0.00032 20.6 1.5 2.2 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 AAG08820.1 - 0.00015 21.1 1.5 0.021 14.1 0.2 2.7 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion PTS_EIIA_1 PF00358.20 AAG08820.1 - 0.0075 16.0 0.3 0.28 10.9 0.2 2.6 1 1 1 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NQRA PF05896.11 AAG08820.1 - 0.0087 15.5 0.3 0.015 14.8 0.3 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_3 PF13437.6 AAG08820.1 - 0.022 15.4 2.3 2.7 8.8 0.2 3.0 3 0 0 3 3 3 0 HlyD family secretion protein QRPTase_N PF02749.16 AAG08820.1 - 0.14 12.2 0.2 20 5.3 0.0 2.6 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 AAG08820.1 - 0.15 11.9 2.2 0.16 11.9 0.4 1.9 2 0 0 2 2 2 0 Glycine cleavage H-protein CPSase_L_D2 PF02786.17 AAG08821.1 - 1.8e-73 246.5 0.2 2.6e-73 246.0 0.2 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAG08821.1 - 2.1e-43 147.3 0.1 5.2e-43 146.1 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAG08821.1 - 2.3e-41 140.3 0.0 5.7e-41 139.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AAG08821.1 - 1.1e-10 41.5 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAG08821.1 - 7.3e-09 35.4 0.1 1.6e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AAG08821.1 - 0.00021 21.0 0.0 0.0036 16.9 0.0 2.7 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AAG08821.1 - 0.00022 21.3 0.0 0.0005 20.2 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAG08821.1 - 0.0026 17.4 0.0 0.0053 16.4 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 AAG08821.1 - 0.032 13.7 0.0 0.073 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain LysR_substrate PF03466.20 AAG08822.1 - 1.2e-51 175.0 3.7 1.2e-51 175.0 3.7 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAG08822.1 - 2.5e-20 72.2 0.1 7.9e-20 70.6 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAG08822.1 - 0.043 12.9 0.0 0.19 10.8 0.0 2.2 1 1 0 1 1 1 0 PBP superfamily domain DUF349 PF03993.12 AAG08822.1 - 0.065 13.5 1.8 0.75 10.1 0.5 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) WXG100 PF06013.12 AAG08822.1 - 0.12 12.6 0.1 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG HTH_6 PF01418.17 AAG08823.1 - 4.4e-25 87.5 0.5 7.6e-25 86.7 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 AAG08823.1 - 5.8e-16 58.5 0.5 8.7e-16 58.0 0.5 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AAG08823.1 - 0.00027 21.0 1.7 0.0065 16.5 0.0 2.4 1 1 1 2 2 2 1 SIS domain G6PD_C PF02781.16 AAG08824.1 - 3.8e-121 403.8 0.0 4.8e-121 403.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AAG08824.1 - 3.7e-55 187.3 0.0 1.2e-54 185.6 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Peptidase_U32 PF01136.19 AAG08825.1 - 8e-98 326.2 0.0 1e-97 325.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family U32 Peptidase_U32_C PF16325.5 AAG08825.1 - 3.8e-20 71.9 0.0 7.9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family U32 C-terminal domain Tachystatin_B PF11478.8 AAG08825.1 - 0.023 14.6 1.2 0.048 13.6 1.2 1.5 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B TPR_2 PF07719.17 AAG08826.1 - 8.8 6.7 14.6 7.4 7.0 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat EAL PF00563.20 AAG08827.1 - 1.2e-72 244.3 0.1 1.2e-72 244.3 0.1 3.1 4 0 0 4 4 4 1 EAL domain GGDEF PF00990.21 AAG08827.1 - 1.2e-41 142.2 0.5 2.4e-41 141.2 0.5 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAG08827.1 - 2e-25 88.9 0.7 5.3e-17 61.9 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAG08827.1 - 1.6e-17 63.7 0.0 3.1e-16 59.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAG08827.1 - 3.5e-14 52.8 0.1 6e-13 48.8 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAG08827.1 - 1.8e-12 47.5 13.0 3.4e-10 40.2 0.2 4.0 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 AAG08827.1 - 3.6e-07 30.1 0.0 3e-06 27.1 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 AAG08827.1 - 0.037 14.2 0.3 0.24 11.6 0.0 2.6 3 0 0 3 3 3 0 PAS fold Filament PF00038.21 AAG08827.1 - 0.34 10.5 7.9 0.43 10.1 2.7 2.5 2 0 0 2 2 2 0 Intermediate filament protein PI3K_P85_iSH2 PF16454.5 AAG08827.1 - 1.3 8.6 4.7 0.55 9.8 1.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2070 PF09843.9 AAG08827.1 - 1.9 6.7 11.8 3 6.0 11.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Tropomyosin_1 PF12718.7 AAG08827.1 - 2.6 8.2 8.6 1.4 9.1 2.9 2.4 2 0 0 2 2 2 0 Tropomyosin like UvrD_C PF13361.6 AAG08828.1 - 3.8e-76 256.7 0.2 1.5e-75 254.8 0.2 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 AAG08828.1 - 2.7e-74 250.5 0.0 6.8e-74 249.2 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAG08828.1 - 6.4e-32 110.9 0.0 1.2e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAG08828.1 - 3.2e-10 39.7 0.0 7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AAG08828.1 - 7.8e-09 35.5 0.2 0.00045 20.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAG08828.1 - 0.00087 19.1 0.1 0.16 11.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Exonuc_V_gamma PF04257.14 AAG08828.1 - 0.0036 15.6 0.0 0.0072 14.6 0.0 1.4 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit AAA_22 PF13401.6 AAG08828.1 - 0.013 15.8 0.0 2.2 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RHH_1 PF01402.21 AAG08828.1 - 0.043 13.8 0.6 0.52 10.3 0.0 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family EamA PF00892.20 AAG08829.1 - 2e-24 86.3 16.8 2.3e-24 86.1 16.8 1.0 1 0 0 1 1 1 1 EamA-like transporter family Mg_trans_NIPA PF05653.14 AAG08829.1 - 5.7e-08 32.2 5.1 8.2e-08 31.7 4.6 1.6 1 1 1 2 2 2 1 Magnesium transporter NIPA SLC35F PF06027.12 AAG08829.1 - 0.0011 18.6 1.6 0.0012 18.5 1.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EmrE PF13536.6 AAG08829.1 - 0.0027 17.4 3.9 0.0027 17.4 3.9 1.4 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter Multi_Drug_Res PF00893.19 AAG08829.1 - 0.0065 17.1 4.8 0.014 16.0 2.0 2.2 1 1 1 2 2 2 1 Small Multidrug Resistance protein CRT-like PF08627.10 AAG08829.1 - 0.013 14.4 2.9 0.02 13.9 0.4 2.0 1 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 AAG08829.1 - 0.014 14.6 0.3 0.014 14.6 0.3 2.0 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF1129 PF06570.11 AAG08829.1 - 0.072 12.6 2.8 0.089 12.3 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) AcetylCoA_hyd_C PF13336.6 AAG08830.1 - 1.4e-40 138.7 0.0 2.5e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 AAG08830.1 - 7.1e-32 111.0 0.0 1.4e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.12 AAG08830.1 - 2.5e-08 33.3 0.3 1.1e-06 27.9 0.1 2.7 4 0 0 4 4 4 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 AAG08830.1 - 2e-06 27.4 1.5 0.00023 20.6 0.0 3.1 3 0 0 3 3 3 1 Coenzyme A transferase LUD_dom PF02589.15 AAG08830.1 - 0.00058 19.6 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 LUD domain DUF1127 PF06568.11 AAG08831.1 - 8.5e-10 38.2 6.4 8.5e-10 38.2 6.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1127) Glycos_transf_1 PF00534.20 AAG08832.1 - 8.6e-33 113.3 0.0 1.3e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG08832.1 - 5.9e-23 81.8 0.0 1e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG08832.1 - 1.5e-15 57.7 0.7 2.4e-15 57.0 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAG08832.1 - 3.9e-07 30.4 0.0 8.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAG08832.1 - 1.3e-06 28.9 2.6 2.9e-06 27.8 0.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 AAG08833.1 - 2.4e-26 92.3 0.0 3.8e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG08833.1 - 1.7e-23 83.5 0.0 2.7e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG08833.1 - 4.4e-09 36.6 0.3 8.6e-09 35.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAG08833.1 - 1.9e-06 28.2 0.0 5.1e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAG08834.1 - 1.1e-21 77.2 0.0 1.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAG08834.1 - 4e-15 56.4 0.0 6.5e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAG08834.1 - 0.0019 18.2 0.7 0.12 12.4 0.7 2.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Wzt_C PF14524.6 AAG08835.1 - 7.6e-34 116.8 0.1 2.5e-33 115.1 0.0 1.9 2 0 0 2 2 2 1 Wzt C-terminal domain ABC_tran PF00005.27 AAG08835.1 - 5.7e-21 75.5 0.1 2.9e-20 73.2 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAG08835.1 - 9e-05 22.4 0.6 0.042 13.7 0.1 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AAG08835.1 - 0.0013 18.5 0.4 0.0046 16.7 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAG08835.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG08835.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AAG08835.1 - 0.017 15.7 0.0 0.031 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAG08835.1 - 0.022 15.1 0.4 5.2 7.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAG08835.1 - 0.054 13.9 0.2 0.47 10.9 0.1 2.4 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAG08835.1 - 0.055 13.5 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 AAG08835.1 - 0.093 12.2 0.2 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 AAG08836.1 - 5.6e-29 101.1 18.1 8.7e-29 100.4 18.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter CRM1_repeat PF18777.1 AAG08836.1 - 0.17 11.4 0.3 0.39 10.3 0.3 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat ABC2_membrane_3 PF12698.7 AAG08836.1 - 5.8 5.9 22.3 0.45 9.6 17.4 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein MannoseP_isomer PF01050.18 AAG08837.1 - 1e-67 226.7 1.4 1.8e-67 225.9 1.4 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 AAG08837.1 - 6.3e-54 183.2 0.0 9.5e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAG08837.1 - 1e-09 39.0 3.2 1e-09 39.0 3.2 2.0 2 1 0 2 2 2 1 MobA-like NTP transferase domain Cupin_2 PF07883.11 AAG08837.1 - 9.2e-09 34.9 0.4 3.6e-08 33.0 0.4 2.1 1 0 0 1 1 1 1 Cupin domain VEK-30 PF12107.8 AAG08837.1 - 0.12 12.3 0.9 0.32 11.0 0.9 1.7 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway GDP_Man_Dehyd PF16363.5 AAG08838.1 - 1e-123 413.0 0.0 1.3e-123 412.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAG08838.1 - 2e-61 207.6 0.0 2.5e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG08838.1 - 8.8e-08 31.6 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AAG08838.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 AAG08838.1 - 0.014 15.4 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 AAG08838.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase MCH PF02289.16 AAG08838.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Cyclohydrolase (MCH) GDP_Man_Dehyd PF16363.5 AAG08839.1 - 7.7e-53 180.0 0.0 7.3e-50 170.2 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAG08839.1 - 2.6e-47 161.3 0.0 3.3e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG08839.1 - 5.2e-12 45.4 0.0 8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAG08839.1 - 2.9e-09 36.5 0.0 2.3e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 AAG08839.1 - 1.4e-06 27.6 0.0 2.7e-05 23.3 0.0 2.0 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAG08839.1 - 1.1e-05 24.7 0.0 0.085 12.0 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Glyco_trans_1_4 PF13692.6 AAG08840.1 - 1e-08 35.7 0.0 2.6e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAG08840.1 - 3.5e-08 33.2 0.0 1.3e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAG08840.1 - 0.00032 21.0 1.3 0.0051 17.2 1.3 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Retrotrans_gag PF03732.17 AAG08840.1 - 0.045 14.0 0.1 6.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Glyco_trans_1_4 PF13692.6 AAG08841.1 - 2.1e-06 28.2 0.0 4.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAG08841.1 - 0.00049 19.7 0.0 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAG08841.1 - 0.14 12.6 0.6 0.89 10.0 0.6 2.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_23 PF13489.6 AAG08842.1 - 1.1e-15 57.8 0.0 1.6e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08842.1 - 1.7e-13 51.0 0.0 2.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08842.1 - 2e-11 44.4 0.1 5.6e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08842.1 - 1.1e-09 38.3 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08842.1 - 1e-06 29.4 0.0 1.6e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AAG08842.1 - 1.7e-05 24.5 0.0 0.001 18.7 0.0 2.3 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 AAG08842.1 - 0.0055 16.3 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 AAG08842.1 - 0.0076 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 AAG08842.1 - 0.0095 15.4 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB adh_short_C2 PF13561.6 AAG08842.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PrmA PF06325.13 AAG08842.1 - 0.28 10.5 0.1 0.47 9.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Acyl_transf_3 PF01757.22 AAG08843.1 - 2e-26 92.9 34.9 2.6e-26 92.5 34.9 1.1 1 0 0 1 1 1 1 Acyltransferase family Methyltransf_11 PF08241.12 AAG08844.1 - 9.2e-18 64.7 0.0 1.5e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG08844.1 - 1.3e-17 64.1 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAG08844.1 - 1.1e-14 54.9 0.1 1.9e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08844.1 - 6.8e-11 42.8 0.0 1.2e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08844.1 - 3.3e-10 39.9 0.0 4.4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAG08844.1 - 5.4e-07 29.2 0.0 6.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 AAG08844.1 - 1e-06 28.2 0.0 5.3e-06 25.9 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 AAG08844.1 - 0.00016 21.3 0.0 0.00068 19.3 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW NodS PF05401.11 AAG08844.1 - 0.0022 17.7 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 AAG08844.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.16 AAG08844.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme MTS PF05175.14 AAG08844.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 AAG08844.1 - 0.045 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1127 PF06568.11 AAG08845.1 - 8.7e-12 44.6 0.2 1.1e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) PKS_DE PF18369.1 AAG08845.1 - 0.059 13.9 1.4 0.1 13.2 0.4 1.9 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain DUF2388 PF09498.10 AAG08846.1 - 4.3e-32 109.9 1.4 4.3e-32 109.9 1.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2388) DUF4148 PF13663.6 AAG08846.1 - 1.5 9.1 5.2 2.2 8.5 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) DUF2388 PF09498.10 AAG08847.1 - 1.9e-31 107.8 1.1 2.4e-31 107.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) DUF2388 PF09498.10 AAG08848.1 - 2.7e-31 107.3 4.8 2.7e-31 107.3 4.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2388) GDH_N PF12466.8 AAG08848.1 - 0.04 14.1 1.4 0.049 13.8 0.4 1.7 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal DUF4105 PF13387.6 AAG08849.1 - 3.6e-31 108.1 0.0 7.3e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) Peptidase_M90 PF06167.12 AAG08849.1 - 0.044 13.4 0.2 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 DUF5388 PF17363.2 AAG08849.1 - 0.15 12.2 0.1 0.87 9.8 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5388) Peptidase_M76 PF09768.9 AAG08849.1 - 0.23 11.2 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M76 family GFA PF04828.14 AAG08850.1 - 6.6e-19 68.0 0.5 6.6e-19 68.0 0.5 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Mem_trans PF03547.18 AAG08851.1 - 8.3e-12 44.2 11.3 5.5e-08 31.6 7.4 2.1 1 1 1 2 2 2 2 Membrane transport protein SBF PF01758.16 AAG08851.1 - 0.0013 18.4 3.4 0.0013 18.4 3.4 2.0 1 1 0 2 2 2 1 Sodium Bile acid symporter family DUF2388 PF09498.10 AAG08852.1 - 2.2e-21 75.6 3.6 3.1e-21 75.1 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) CitMHS PF03600.16 AAG08853.1 - 4.4e-56 190.3 36.4 4.4e-56 190.3 36.4 1.8 2 0 0 2 2 2 1 Citrate transporter TerC PF03741.16 AAG08854.1 - 7.6e-51 172.4 12.8 9.7e-51 172.0 12.8 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family TPPK_C PF12555.8 AAG08854.1 - 0.06 13.4 1.9 0.06 13.4 1.9 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal AveC_like PF17198.4 AAG08854.1 - 0.091 12.2 2.4 0.2 11.1 2.4 1.5 1 0 0 1 1 1 0 Spirocyclase AveC-like TMCCDC2 PF15844.5 AAG08854.1 - 0.99 9.3 3.8 0.64 9.9 0.1 2.1 1 1 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 DUF4781 PF16013.5 AAG08854.1 - 4 6.2 5.8 6.3 5.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) AC_N PF16214.5 AAG08854.1 - 4.5 6.3 7.2 7.5 5.6 7.2 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RF-1 PF00472.20 AAG08855.1 - 8.5e-23 80.5 0.3 1.3e-22 80.0 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain RtcB PF01139.17 AAG08856.1 - 1.2e-67 228.9 0.0 3.9e-56 191.0 0.0 2.6 2 1 0 2 2 2 2 tRNA-splicing ligase RtcB SBP_bac_3 PF00497.20 AAG08857.1 - 1.2e-06 28.2 0.0 0.00015 21.3 0.0 2.0 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Na_Pi_cotrans PF02690.15 AAG08858.1 - 3.6e-44 150.2 23.6 5.9e-35 120.4 9.6 2.2 2 0 0 2 2 2 2 Na+/Pi-cotransporter PhoU PF01895.19 AAG08858.1 - 1.4e-12 47.9 5.2 9.9e-12 45.2 1.4 2.4 2 0 0 2 2 2 2 PhoU domain Peptidase_M16_C PF05193.21 AAG08859.1 - 1.2e-15 58.0 0.0 2.6e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AAG08859.1 - 2.7e-14 53.4 0.0 4.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Acetyltransf_3 PF13302.7 AAG08860.1 - 0.00041 21.0 0.0 0.00052 20.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAG08860.1 - 0.00042 20.5 0.0 0.00058 20.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAG08860.1 - 0.062 13.2 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAG08860.1 - 0.07 13.3 0.0 0.084 13.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IGPS PF00218.21 AAG08860.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Sugar_tr PF00083.24 AAG08861.1 - 2.2e-32 112.5 21.9 6.3e-24 84.6 7.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAG08861.1 - 2.9e-30 105.4 60.9 8e-27 94.1 38.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 AAG08861.1 - 9e-05 21.4 3.1 9e-05 21.4 3.1 1.9 2 0 0 2 2 2 1 LacY proton/sugar symporter DUF2914 PF11141.8 AAG08862.1 - 1.5e-24 85.5 0.2 2.8e-24 84.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2914) YiaAB PF05360.14 AAG08862.1 - 0.047 13.9 1.9 0.047 13.9 1.9 2.8 2 0 0 2 2 2 0 yiaA/B two helix domain DUF3017 PF11222.8 AAG08862.1 - 0.75 10.1 7.3 5.2 7.4 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) DUF2070 PF09843.9 AAG08862.1 - 6.3 5.0 11.7 9.8 4.3 11.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Gate PF07670.14 AAG08863.1 - 3.8e-12 46.5 16.5 1.2e-07 32.0 0.5 3.5 3 1 0 3 3 3 2 Nucleoside recognition SDF PF00375.18 AAG08864.1 - 2.9e-119 398.6 39.9 3.3e-119 398.4 39.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Ivy PF08816.11 AAG08866.1 - 4.7e-47 159.0 0.1 5.8e-47 158.7 0.1 1.1 1 0 0 1 1 1 1 Inhibitor of vertebrate lysozyme (Ivy) DUF1328 PF07043.13 AAG08867.1 - 8.3e-17 61.1 23.6 1e-16 60.8 23.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1328) DUF2981 PF11200.8 AAG08867.1 - 0.98 9.1 6.1 1.1 9.0 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4870 PF09685.10 AAG08867.1 - 4.3 7.5 9.6 4.9 7.3 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) Adeno_E3_CR2 PF02439.15 AAG08867.1 - 5.1 6.9 9.4 8.7 6.2 1.6 2.3 2 1 0 2 2 2 0 Adenovirus E3 region protein CR2 Sigma54_activat PF00158.26 AAG08868.1 - 3.3e-63 212.4 0.0 5.3e-63 211.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAG08868.1 - 2.1e-29 101.9 0.0 4.4e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAG08868.1 - 7.5e-18 65.0 0.0 7.5e-17 61.7 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAG08868.1 - 6e-10 38.7 1.2 1.1e-09 38.0 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAG08868.1 - 2.5e-06 27.5 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAG08868.1 - 5.9e-06 25.8 0.1 0.00019 20.9 0.1 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAG08868.1 - 2e-05 25.0 0.0 4.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAG08868.1 - 0.001 19.3 0.2 0.0041 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 AAG08868.1 - 0.0064 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AAG08868.1 - 0.01 16.3 0.1 0.028 14.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 AAG08868.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1858 PF08984.11 AAG08868.1 - 0.017 15.3 0.0 0.069 13.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) MCM PF00493.23 AAG08868.1 - 0.025 13.7 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain HTH_50 PF18024.1 AAG08868.1 - 0.1 12.2 0.2 0.27 10.9 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAG08868.1 - 0.1 12.4 0.0 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.7 AAG08868.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AAG08868.1 - 0.13 12.3 0.4 0.72 9.9 0.1 2.4 3 0 0 3 3 3 0 Winged helix-turn helix KinB_sensor PF16767.5 AAG08869.1 - 1.9e-38 131.6 5.8 6.8e-38 129.8 5.8 2.0 1 0 0 1 1 1 1 Sensor domain of alginate biosynthesis sensor protein KinB HATPase_c PF02518.26 AAG08869.1 - 1.3e-24 86.9 0.0 3.2e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAG08869.1 - 7e-12 45.2 7.5 7.5e-12 45.1 0.3 3.6 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAG08869.1 - 1.6e-11 44.4 0.7 1.6e-11 44.4 0.7 2.5 3 0 0 3 3 3 1 HAMP domain PAS_4 PF08448.10 AAG08869.1 - 5.3e-11 42.8 1.1 9.5e-11 41.9 0.2 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAG08869.1 - 1.6e-06 28.0 1.0 1.4e-05 25.0 0.1 2.8 3 0 0 3 3 2 1 PAS domain PAS_9 PF13426.7 AAG08869.1 - 2.7e-06 27.6 0.0 1.7e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 PAS domain HATPase_c_5 PF14501.6 AAG08869.1 - 4.1e-05 23.4 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAG08869.1 - 0.0066 16.4 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS PF00989.25 AAG08869.1 - 0.0097 15.9 0.0 0.039 14.0 0.0 2.1 1 1 0 1 1 1 1 PAS fold PAS_7 PF12860.7 AAG08869.1 - 0.063 13.4 2.2 1.4 9.1 0.0 3.6 4 0 0 4 4 4 0 PAS fold MatE PF01554.18 AAG08869.1 - 0.11 12.2 0.6 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 MatE HATPase_c_3 PF13589.6 AAG08869.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidase_2 PF01510.25 AAG08870.1 - 1.6e-31 109.4 0.0 2.2e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 AAG08870.1 - 4.6e-09 36.3 0.1 1.2e-08 35.0 0.1 1.7 2 0 0 2 2 2 1 Putative peptidoglycan binding domain MarC PF01914.17 AAG08871.1 - 1.5e-42 145.3 11.2 1.8e-42 145.1 11.2 1.1 1 0 0 1 1 1 1 MarC family integral membrane protein TerC PF03741.16 AAG08871.1 - 0.0021 17.8 7.2 0.0057 16.4 0.4 2.2 2 0 0 2 2 2 2 Integral membrane protein TerC family GGDEF PF00990.21 AAG08872.1 - 2.6e-47 160.6 0.1 1.1e-46 158.5 0.0 2.2 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAG08872.1 - 8.2e-06 26.1 10.5 0.0043 17.3 1.0 4.3 2 2 1 4 4 4 2 GGDEF-like domain Dynactin_p22 PF07426.11 AAG08872.1 - 0.29 11.0 5.3 1.5 8.7 1.2 2.6 2 0 0 2 2 2 0 Dynactin subunit p22 DUF445 PF04286.12 AAG08872.1 - 1.6 8.5 7.5 3.6 7.3 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF445) DUF87 PF01935.17 AAG08872.1 - 2 8.5 4.6 21 5.1 0.5 2.7 2 1 1 3 3 3 0 Helicase HerA, central domain SpecificRecomb PF10136.9 AAG08872.1 - 2.3 6.4 4.6 2.5 6.3 0.2 2.1 2 0 0 2 2 2 0 Site-specific recombinase COG2 PF06148.11 AAG08872.1 - 2.4 8.3 6.8 6.3 6.9 2.7 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 AAG08872.1 - 4 7.5 6.1 6.8 6.8 3.1 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) RmuC PF02646.16 AAG08872.1 - 6.7 5.7 8.5 1.4 8.0 3.1 2.4 2 1 1 3 3 3 0 RmuC family Exo_endo_phos PF03372.23 AAG08873.1 - 2.2e-12 47.0 0.8 3.1e-12 46.5 0.8 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AAG08873.1 - 0.041 13.7 0.1 0.77 9.6 0.1 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase YlbE PF14003.6 AAG08873.1 - 0.21 12.1 0.2 0.42 11.1 0.2 1.5 1 0 0 1 1 1 0 YlbE-like protein DSBA PF01323.20 AAG08874.1 - 7.3e-17 61.8 3.4 4.3e-15 56.0 0.3 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AAG08874.1 - 2.8e-06 27.6 0.2 7.2e-06 26.3 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 AAG08874.1 - 0.00012 22.1 0.1 0.47 10.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_5 PF13743.6 AAG08874.1 - 0.00017 21.3 0.0 0.0051 16.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 AAG08874.1 - 0.00021 21.3 0.0 0.0058 16.6 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain DUF953 PF06110.11 AAG08874.1 - 0.0081 15.8 0.0 0.064 12.9 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF953) DUF929 PF06053.11 AAG08874.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Thioredoxin_2 PF13098.6 AAG08874.1 - 0.054 13.9 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Cytochrom_C PF00034.21 AAG08875.1 - 2.4e-18 67.1 3.8 1e-07 32.9 1.4 2.9 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAG08875.1 - 1.3e-14 54.2 0.8 1e-06 28.9 0.1 2.2 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 AAG08875.1 - 0.0041 16.8 1.0 1.6 8.5 0.1 2.4 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) DUF1924 PF09086.11 AAG08875.1 - 0.022 15.1 0.2 7.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Cytochrome_C7 PF14522.6 AAG08875.1 - 0.027 14.5 0.1 6.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF3365 PF11845.8 AAG08875.1 - 0.25 11.6 0.5 16 5.8 0.2 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3365) Cytochrome_CBB3 PF13442.6 AAG08876.1 - 1.3e-13 51.1 0.7 1.5e-13 50.8 0.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 AAG08876.1 - 0.017 15.1 0.3 0.058 13.4 0.3 1.8 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c MMR_HSR1 PF01926.23 AAG08877.1 - 2.4e-17 63.1 0.0 3.4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAG08877.1 - 0.00068 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AAG08877.1 - 0.00082 19.3 0.0 0.047 13.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 AAG08877.1 - 0.0054 16.8 0.0 0.1 12.7 0.0 2.1 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 AAG08877.1 - 0.17 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DNA_pol_A PF00476.20 AAG08878.1 - 3.6e-153 510.1 0.0 5e-153 509.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 AAG08878.1 - 6.4e-51 172.4 0.0 1e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DNA_pol_A_exo1 PF01612.20 AAG08878.1 - 4.6e-39 133.9 2.4 1.2e-38 132.5 0.3 2.5 3 0 0 3 3 3 1 3'-5' exonuclease 5_3_exonuc PF01367.20 AAG08878.1 - 2.6e-27 95.3 0.0 7e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold SCP2 PF02036.17 AAG08878.1 - 0.084 13.4 0.1 7.3 7.2 0.0 2.6 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF2782 PF11191.8 AAG08879.1 - 7.3e-24 83.8 0.0 8.5e-24 83.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2782) APH PF01636.23 AAG08880.1 - 7.3e-37 127.6 8.0 9.7e-37 127.2 8.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAG08880.1 - 0.0044 16.6 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ribonuc_red_lgC PF02867.15 AAG08882.1 - 1.6e-140 469.1 0.0 1.9e-140 468.9 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain TetR_C_7 PF14246.6 AAG08882.1 - 0.007 16.4 0.1 0.19 11.7 0.0 2.6 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain ZnuA PF01297.17 AAG08883.1 - 1.5e-51 175.3 0.0 1.6e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic FUR PF01475.19 AAG08884.1 - 6.3e-12 45.7 0.0 1.4e-11 44.6 0.0 1.5 2 0 0 2 2 2 1 Ferric uptake regulator family PadR PF03551.14 AAG08884.1 - 0.0025 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Penicillinase_R PF03965.16 AAG08884.1 - 0.019 15.3 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor DUF2318 PF10080.9 AAG08884.1 - 0.047 13.8 0.5 0.08 13.1 0.1 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) TBPIP PF07106.13 AAG08884.1 - 0.047 13.6 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain MarR PF01047.22 AAG08884.1 - 0.054 13.4 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 MarR family ABC_tran PF00005.27 AAG08885.1 - 5.5e-26 91.7 0.0 7.7e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAG08885.1 - 5.7e-10 39.5 0.8 8.9e-05 22.4 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAG08885.1 - 5.5e-05 23.4 0.0 0.00016 21.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAG08885.1 - 5.6e-05 23.6 0.2 9.7e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAG08885.1 - 0.0006 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAG08885.1 - 0.0034 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase TsaE PF02367.17 AAG08885.1 - 0.0084 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AAG08885.1 - 0.0085 15.7 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAG08885.1 - 0.0086 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAG08885.1 - 0.0088 16.2 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAG08885.1 - 0.009 16.5 0.0 0.013 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAG08885.1 - 0.01 15.6 0.1 0.027 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAG08885.1 - 0.014 14.6 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain SMC_N PF02463.19 AAG08885.1 - 0.016 14.7 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 AAG08885.1 - 0.019 14.7 0.1 7.2 6.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 AAG08885.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAG08885.1 - 0.063 13.2 0.3 0.13 12.2 0.1 1.6 2 0 0 2 2 1 0 NACHT domain Mg_chelatase PF01078.21 AAG08885.1 - 0.087 12.2 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 AAG08885.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAG08885.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 AAG08885.1 - 0.15 12.0 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 NTPase PSY3 PF16836.5 AAG08885.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description AAA_7 PF12775.7 AAG08885.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 AAG08885.1 - 0.21 11.9 0.1 1.5 9.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AAG08885.1 - 0.21 11.2 0.2 0.21 11.2 0.2 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 AAG08885.1 - 0.26 11.2 0.0 0.38 10.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 AAG08885.1 - 0.26 10.0 0.2 17 4.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 AAG08885.1 - 0.31 10.7 0.1 0.49 10.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AAG08885.1 - 0.94 9.4 2.6 0.97 9.3 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC-3 PF00950.17 AAG08886.1 - 2.2e-78 263.3 28.5 2.5e-78 263.2 28.5 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AAG08886.1 - 1.3e-07 31.0 32.5 2.3e-07 30.2 32.5 1.5 1 1 0 1 1 1 1 FecCD transport family DUF2370 PF10176.9 AAG08886.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PBP_N PF17093.5 AAG08886.1 - 0.93 9.7 2.2 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus stn_TNFRSF12A PF12191.8 AAG08886.1 - 2.2 8.5 13.7 0.95 9.7 1.0 3.0 1 1 2 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF357 PF04010.13 AAG08887.1 - 0.0051 16.9 0.2 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF357) ABC_tran PF00005.27 AAG08888.1 - 5.2e-36 124.2 0.0 7.4e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter NIL PF09383.10 AAG08888.1 - 3.6e-19 68.4 0.0 7.3e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 AAG08888.1 - 1.5e-06 28.3 0.1 0.041 13.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAG08888.1 - 2e-05 24.2 0.1 0.00032 20.2 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAG08888.1 - 0.00042 20.7 0.8 0.0011 19.4 0.6 1.8 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 AAG08888.1 - 0.0005 20.4 0.1 0.0048 17.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAG08888.1 - 0.00067 19.4 0.0 0.0087 15.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAG08888.1 - 0.0039 17.1 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAG08888.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AAG08888.1 - 0.013 15.9 0.1 0.21 12.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 AAG08888.1 - 0.054 13.7 1.3 0.35 11.1 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 AAG08888.1 - 0.065 12.8 0.3 1.3 8.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 AAG08888.1 - 0.089 12.2 0.0 0.91 8.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_23 PF13476.6 AAG08888.1 - 0.095 13.2 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAG08888.1 - 0.098 12.7 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 AAG08888.1 - 0.13 12.2 0.1 12 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAG08888.1 - 0.16 12.2 0.1 0.31 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAG08889.1 - 6.3e-20 71.7 17.4 6.3e-20 71.7 17.4 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Lipoprotein_9 PF03180.14 AAG08890.1 - 2e-102 341.3 4.1 2.3e-102 341.1 4.1 1.0 1 0 0 1 1 1 1 NLPA lipoprotein DUF693 PF05113.13 AAG08890.1 - 0.017 14.4 0.1 0.031 13.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF693) Phosphonate-bd PF12974.7 AAG08890.1 - 0.039 13.5 0.2 6.6 6.2 0.0 2.5 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein SIS PF01380.22 AAG08891.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 AAG08891.1 - 6.9e-12 45.2 0.0 2.5e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family MarR_2 PF12802.7 AAG08891.1 - 0.00058 19.7 0.1 0.003 17.4 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_Tnp_ISL3 PF13542.6 AAG08891.1 - 0.0022 17.3 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_36 PF13730.6 AAG08891.1 - 0.13 12.2 0.0 0.42 10.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Isochorismatase PF00857.20 AAG08892.1 - 1.5e-35 123.0 0.1 1.7e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Gln-synt_C PF00120.24 AAG08893.1 - 3.1e-88 296.1 0.0 6e-88 295.1 0.0 1.4 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 AAG08893.1 - 5.4e-45 151.6 0.0 1.4e-44 150.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain FGase PF05013.12 AAG08894.1 - 4.1e-38 131.8 0.6 5e-38 131.5 0.6 1.0 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase AA_permease PF00324.21 AAG08895.1 - 2.3e-33 115.5 26.4 3.1e-33 115.1 26.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAG08895.1 - 3.3e-29 102.0 29.6 4.4e-29 101.6 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2953 PF11167.8 AAG08895.1 - 3.9 7.6 5.9 35 4.6 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DUF3302 PF11742.8 AAG08895.1 - 5.1 7.3 12.2 0.24 11.5 0.3 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3302) Sigma54_activat PF00158.26 AAG08896.1 - 3.4e-67 225.3 0.0 4.8e-67 224.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAG08896.1 - 3.5e-29 101.2 0.0 7.5e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAG08896.1 - 1.3e-22 80.4 0.0 4.2e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAG08896.1 - 1.8e-07 31.3 0.1 0.0001 22.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) HTH_8 PF02954.19 AAG08896.1 - 3.7e-07 29.8 1.4 1.2e-06 28.2 0.4 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 AAG08896.1 - 0.00014 21.4 0.5 0.017 14.5 0.1 2.8 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAG08896.1 - 0.0013 19.2 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FleQ PF06490.11 AAG08896.1 - 0.032 14.6 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ AAA_16 PF13191.6 AAG08896.1 - 0.035 14.5 0.5 0.17 12.3 0.2 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_3 PF07726.11 AAG08896.1 - 0.05 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAG08896.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MCM PF00493.23 AAG08896.1 - 0.15 11.1 0.0 0.37 9.8 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain HATPase_c PF02518.26 AAG08897.1 - 8.3e-18 64.9 0.0 1.3e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAG08897.1 - 2.5e-09 37.3 0.5 2e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Cache domain HisKA PF00512.25 AAG08897.1 - 5.4e-07 29.5 1.6 5.4e-07 29.5 1.6 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAG08897.1 - 0.00088 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAG08897.1 - 0.0067 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 GHKL domain Abhydrolase_6 PF12697.7 AAG08898.1 - 1.9e-15 58.1 5.7 2.6e-15 57.6 5.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAG08898.1 - 9.3e-14 51.3 0.0 3.2e-13 49.5 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAG08898.1 - 5.3e-11 42.7 0.0 4.5e-09 36.3 0.2 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAG08898.1 - 0.00043 19.8 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 AAG08898.1 - 0.0098 15.6 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Transpeptidase PF00905.22 AAG08899.1 - 1.6e-25 90.0 0.0 2.4e-24 86.1 0.0 2.0 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain Beta-lactamase2 PF13354.6 AAG08899.1 - 3.5e-05 23.5 0.0 0.00014 21.5 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase enzyme family DUF3301 PF11743.8 AAG08900.1 - 2.9e-34 116.6 0.9 4e-34 116.2 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3301) Phos_pyr_kin PF08543.12 AAG08901.1 - 2.5e-12 46.7 0.0 3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AAG08901.1 - 1e-07 31.6 0.0 5e-07 29.3 0.0 2.1 2 1 0 2 2 2 1 pfkB family carbohydrate kinase SNARE_assoc PF09335.11 AAG08902.1 - 3.5e-08 33.9 6.0 3.5e-08 33.9 6.0 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3169 PF11368.8 AAG08902.1 - 0.022 14.3 1.4 0.023 14.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Na_H_Exchanger PF00999.21 AAG08903.1 - 3.6e-76 256.4 49.3 4.5e-76 256.1 49.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AAG08903.1 - 3.8e-23 82.0 0.0 6.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 AAG08903.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 4HBT PF03061.22 AAG08904.1 - 2.2e-18 66.4 0.4 4e-18 65.5 0.4 1.4 1 0 0 1 1 1 1 Thioesterase superfamily TPR_2 PF07719.17 AAG08905.1 - 0.00015 21.6 0.7 0.78 10.0 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAG08905.1 - 0.0015 18.8 2.9 0.004 17.4 2.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAG08905.1 - 0.018 15.6 5.6 0.092 13.4 5.6 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAG08905.1 - 0.037 13.9 1.5 5.4 7.0 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAG08905.1 - 0.062 13.7 0.1 0.22 12.0 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAG08905.1 - 1.3 9.9 6.7 2 9.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 AAG08906.1 - 6.1e-59 199.4 0.1 7.2e-59 199.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG08906.1 - 5.6e-52 176.1 0.0 6.5e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG08906.1 - 5.1e-11 42.8 1.4 2.9e-10 40.3 1.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAG08906.1 - 0.00024 20.7 0.1 0.00037 20.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAG08906.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 AAG08906.1 - 0.021 14.7 0.1 0.036 13.9 0.0 1.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 AAG08906.1 - 0.04 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EccE PF11203.8 AAG08906.1 - 0.55 10.6 2.4 4.7 7.6 0.1 2.7 3 1 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Gln-synt_C PF00120.24 AAG08907.1 - 1.7e-105 352.9 0.0 1.9e-105 352.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Aminotran_3 PF00202.21 AAG08908.1 - 4.4e-42 144.2 0.0 4.9e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAG08908.1 - 0.00063 19.0 0.0 0.0049 16.1 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II adh_short_C2 PF13561.6 AAG08909.1 - 8.7e-60 202.2 1.2 1.1e-59 201.9 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAG08909.1 - 2.9e-50 170.5 0.1 3.4e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAG08909.1 - 6.6e-09 35.9 0.4 1.2e-08 35.1 0.4 1.4 1 1 0 1 1 1 1 KR domain YjeF_N PF03853.15 AAG08909.1 - 0.011 15.6 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus F420_oxidored PF03807.17 AAG08909.1 - 0.068 13.8 1.4 0.33 11.5 0.3 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FCD PF07729.12 AAG08910.1 - 2.3e-26 92.6 3.2 2.3e-26 92.6 3.2 1.9 3 0 0 3 3 3 1 FCD domain GntR PF00392.21 AAG08910.1 - 3.1e-17 62.0 0.5 6.7e-17 60.9 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family PaaX PF07848.12 AAG08910.1 - 0.017 15.3 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 PaaX-like protein HTH_24 PF13412.6 AAG08910.1 - 0.03 13.9 0.0 0.083 12.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PCI PF01399.27 AAG08910.1 - 0.04 14.4 0.0 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 PCI domain DUF903 PF06004.12 AAG08911.1 - 4.2e-16 58.6 1.2 4.7e-16 58.4 1.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) DUF3157 PF11355.8 AAG08911.1 - 0.0042 16.7 0.0 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3157) SUKH_5 PF14567.6 AAG08912.1 - 3.5e-43 146.7 0.0 3.9e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 AAG08912.1 - 6.9e-08 33.0 0.3 1.1e-06 29.1 0.3 2.0 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 AAG08912.1 - 0.00011 22.6 1.5 0.00077 19.9 1.5 1.9 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall PRP4 PF08799.11 AAG08912.1 - 0.011 15.2 0.2 0.024 14.2 0.2 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Tim44 PF04280.15 AAG08913.1 - 1.6e-08 34.8 1.2 4.4e-08 33.4 1.2 1.7 1 1 0 1 1 1 1 Tim44-like domain RCR PF12273.8 AAG08913.1 - 0.011 16.4 0.0 0.048 14.3 0.0 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red RseC_MucC PF04246.12 AAG08913.1 - 0.024 14.6 0.3 0.043 13.8 0.3 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Na_H_Exchanger PF00999.21 AAG08914.1 - 9.8e-64 215.5 49.1 9.8e-64 215.5 49.1 2.9 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family DUF3464 PF11947.8 AAG08914.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 MFS_1 PF07690.16 AAG08915.1 - 1.1e-38 133.1 49.7 4e-30 104.9 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAG08915.1 - 2.9e-38 131.9 27.7 5.8e-28 98.0 6.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAG08915.1 - 1.1e-05 24.5 16.1 0.01 14.7 9.2 3.6 1 1 1 3 3 3 2 MFS_1 like family MFS_5 PF05631.14 AAG08915.1 - 0.0001 21.4 6.5 0.019 13.9 0.4 2.2 1 1 1 2 2 2 2 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 AAG08915.1 - 0.0023 16.4 6.2 0.0092 14.4 1.1 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 AAG08915.1 - 1.1 8.0 20.0 0.067 11.9 6.9 2.6 2 1 0 2 2 2 0 LacY proton/sugar symporter TonB_C PF03544.14 AAG08916.1 - 1.2e-21 76.9 0.0 3.2e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAG08916.1 - 0.0076 16.5 0.0 0.0076 16.5 0.0 3.3 3 0 0 3 3 3 1 TonB C terminal Ndc1_Nup PF09531.10 AAG08916.1 - 8 5.0 9.1 9.3 4.8 9.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup cobW PF02492.19 AAG08917.1 - 3.8e-39 134.1 0.0 4.7e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AAG08917.1 - 0.026 14.9 0.6 0.13 12.6 0.4 2.2 1 1 1 2 2 2 0 AAA ATPase domain TsaE PF02367.17 AAG08917.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 AAG08917.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAG08917.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1826 PF08856.11 AAG08919.1 - 8.3e-65 218.4 0.1 9.4e-65 218.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1826) cobW PF02492.19 AAG08920.1 - 3.6e-58 196.1 0.1 4.4e-58 195.8 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAG08920.1 - 1.2e-29 102.0 0.2 3.3e-29 100.6 0.2 1.8 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 AAG08920.1 - 1e-05 25.5 0.1 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 AAG08920.1 - 6.1e-05 23.5 0.1 0.00017 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 AAG08920.1 - 0.0029 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 AAG08920.1 - 0.0052 17.0 0.0 0.051 13.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 AAG08920.1 - 0.0098 14.9 0.0 0.16 10.9 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 AAG08920.1 - 0.018 15.3 0.1 0.058 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAG08920.1 - 0.024 15.2 0.0 0.038 14.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 AAG08920.1 - 0.035 14.0 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 AAG08920.1 - 0.038 13.7 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 AAG08920.1 - 0.042 13.9 0.1 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 AAG08920.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin zf-dskA_traR PF01258.17 AAG08921.1 - 2.5e-11 43.3 0.2 4.7e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger TMCO5 PF14992.6 AAG08921.1 - 0.055 13.0 4.3 0.077 12.6 4.3 1.1 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.15 AAG08921.1 - 0.17 11.7 3.6 0.47 10.3 1.0 2.2 1 1 1 2 2 2 0 Septum formation initiator Amidase_3 PF01520.18 AAG08923.1 - 1.3e-45 155.6 0.0 1.7e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 AAG08923.1 - 8.2e-18 64.3 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 AMIN domain GCHY-1 PF02649.14 AAG08924.1 - 1.2e-67 228.1 0.0 1.4e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Type I GTP cyclohydrolase folE2 Hexapep PF00132.24 AAG08925.1 - 3.7e-16 58.1 18.5 2e-06 27.3 0.5 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAG08925.1 - 1.4e-05 24.7 16.2 0.00084 19.0 2.3 4.3 2 2 3 5 5 5 4 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AAG08925.1 - 0.012 14.6 0.3 0.032 13.2 0.3 1.7 1 1 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 AAG08925.1 - 0.73 7.9 2.9 1.1 7.4 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Amidohydro_1 PF01979.20 AAG08926.1 - 1.7e-14 53.9 0.0 3.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 AAG08926.1 - 3.4e-08 33.4 0.1 0.00016 21.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Beta-lactamase PF00144.24 AAG08927.1 - 6.9e-56 189.9 0.6 9.2e-56 189.5 0.6 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF1850 PF08905.11 AAG08928.1 - 1.3e-22 79.9 0.0 1.6e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1850) DctM PF06808.12 AAG08929.1 - 7.5e-89 298.4 56.1 7.7e-88 295.1 46.7 2.5 2 1 0 2 2 2 1 Tripartite ATP-independent periplasmic transporter, DctM component COX7C PF02935.16 AAG08929.1 - 6.4 7.1 6.5 4.7 7.6 0.6 3.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc NMT1_3 PF16868.5 AAG08930.1 - 8.5e-97 324.0 0.8 9.6e-97 323.9 0.8 1.0 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAG08930.1 - 1.1e-06 28.7 0.1 1.6e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAG08930.1 - 1.1e-05 25.1 0.3 1.7e-05 24.6 0.3 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAG08930.1 - 0.00012 21.6 0.0 0.00028 20.4 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CMAS PF02353.20 AAG08931.1 - 2.5e-106 355.0 0.0 2.9e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 AAG08931.1 - 4.2e-18 65.9 0.0 1.6e-17 63.9 0.0 2.1 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08931.1 - 3.2e-15 56.5 0.2 1e-14 54.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAG08931.1 - 2e-11 43.9 0.0 4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAG08931.1 - 3e-11 43.9 0.0 7.2e-11 42.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAG08931.1 - 1.4e-09 38.0 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAG08931.1 - 1.7e-05 24.4 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 AAG08931.1 - 0.0018 18.1 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 AAG08931.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 AAG08931.1 - 0.0022 17.4 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 AAG08931.1 - 0.0065 16.1 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 AAG08931.1 - 0.011 15.7 0.0 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 AAG08931.1 - 0.034 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 AAG08931.1 - 0.05 12.5 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 AAG08931.1 - 0.06 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 AAG08931.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.13 AAG08931.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 ADH_zinc_N PF00107.26 AAG08931.1 - 0.17 11.8 0.2 0.77 9.7 0.0 2.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase FtsJ PF01728.19 AAG08931.1 - 0.19 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase HAD PF12710.7 AAG08932.1 - 2.2e-25 90.2 0.1 2.6e-25 89.9 0.1 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAG08932.1 - 0.12 12.6 0.1 0.79 10.0 0.1 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase stn_TNFRSF12A PF12191.8 AAG08932.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MFS_1 PF07690.16 AAG08933.1 - 2e-42 145.4 66.0 2.4e-35 122.1 40.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AAG08933.1 - 4.2e-09 35.3 29.1 7.2e-09 34.6 22.7 2.3 1 1 1 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.24 AAG08933.1 - 1.3e-08 34.2 22.2 2.2e-07 30.1 13.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAG08933.1 - 2e-06 27.4 22.6 2.3e-05 23.9 16.7 2.3 1 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AAG08933.1 - 0.0004 18.8 3.1 0.0004 18.8 3.1 3.0 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Ceramidase PF05875.12 AAG08933.1 - 0.029 13.8 2.4 0.065 12.7 2.4 1.6 1 0 0 1 1 1 0 Ceramidase TAL_effector PF03377.13 AAG08933.1 - 0.034 14.5 0.0 0.085 13.2 0.0 1.6 1 0 0 1 1 1 0 TAL effector repeat SIS PF01380.22 AAG08934.1 - 1.6e-61 205.9 0.0 3.7e-33 114.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AAG08934.1 - 1.4e-20 73.8 0.0 2.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AAG08934.1 - 6.2e-15 55.2 0.0 1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AAG08934.1 - 0.00033 19.6 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 AAG08934.1 - 0.11 12.5 0.1 0.63 10.1 0.0 2.2 2 1 1 3 3 3 0 SIS domain DeoRC PF00455.22 AAG08935.1 - 3.7e-44 150.5 0.0 5.4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AAG08935.1 - 6.1e-15 54.7 0.0 1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAG08935.1 - 8.7e-08 32.0 0.2 1.8e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 HTH domain HTH_Mga PF08280.11 AAG08935.1 - 0.0001 22.2 0.0 0.0003 20.8 0.0 1.7 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain MarR PF01047.22 AAG08935.1 - 0.00022 21.1 0.2 0.00066 19.6 0.1 1.8 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAG08935.1 - 0.00032 20.7 0.4 0.00074 19.5 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 AAG08935.1 - 0.0021 18.4 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator FeoC PF09012.10 AAG08935.1 - 0.0083 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 FeoC like transcriptional regulator GntR PF00392.21 AAG08935.1 - 0.0088 15.7 2.2 0.02 14.5 0.1 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family Put_DNA-bind_N PF06971.13 AAG08935.1 - 0.015 15.3 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus HTH_AsnC-type PF13404.6 AAG08935.1 - 0.023 14.5 0.7 0.067 13.0 0.1 2.2 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAG08935.1 - 0.086 12.7 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 MarR family HTH_12 PF08461.10 AAG08935.1 - 0.091 12.7 0.1 0.55 10.2 0.0 2.4 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain HTH_5 PF01022.20 AAG08935.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Peptidase_M23 PF01551.22 AAG08936.1 - 8.7e-20 70.7 0.0 1.1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M23 Hexapep PF00132.24 AAG08937.1 - 1.3e-24 84.9 10.4 1.3e-07 31.0 2.3 5.8 3 1 3 6 6 6 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AAG08937.1 - 1.4e-24 87.2 1.4 2.6e-24 86.4 1.4 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 AAG08937.1 - 1.1e-13 51.4 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 AAG08937.1 - 2.1e-11 43.3 17.0 9.5e-05 22.1 0.0 5.2 6 0 0 6 6 6 3 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 AAG08937.1 - 1.2e-07 31.7 1.7 1.5e-07 31.4 0.6 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AAG08937.1 - 0.00048 20.1 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase CofC PF01983.16 AAG08937.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Guanylyl transferase CofC like Fucokinase PF07959.12 AAG08937.1 - 0.049 12.6 0.0 0.84 8.5 0.0 2.1 1 1 1 2 2 2 0 L-fucokinase ATP-synt_DE_N PF02823.16 AAG08938.1 - 3.5e-30 103.7 0.1 4.6e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 AAG08938.1 - 5.1e-07 29.8 12.3 8.4e-07 29.2 12.3 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ATP-synt_ab PF00006.25 AAG08939.1 - 4.6e-63 212.7 0.0 6e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AAG08939.1 - 1.7e-20 73.3 2.0 3.5e-20 72.3 2.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain YdaS_antitoxin PF15943.5 AAG08939.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT ATP-synt PF00231.19 AAG08940.1 - 2.4e-96 322.7 0.2 2.7e-96 322.6 0.2 1.0 1 0 0 1 1 1 1 ATP synthase DUF432 PF04254.13 AAG08940.1 - 0.0064 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF432) ATP-synt_ab PF00006.25 AAG08941.1 - 8.8e-73 244.5 0.2 1.3e-72 243.9 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AAG08941.1 - 1.2e-44 151.7 2.4 1.9e-44 151.0 2.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AAG08941.1 - 1.1e-16 61.1 1.1 2.6e-16 59.9 1.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AAG08941.1 - 3.7e-08 33.4 0.6 8.2e-08 32.3 0.3 1.8 2 0 0 2 2 2 1 HAS barrel domain ATPase_2 PF01637.18 AAG08941.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Nup54 PF13874.6 AAG08941.1 - 0.15 12.2 0.4 0.3 11.2 0.4 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 OSCP PF00213.18 AAG08942.1 - 3.5e-56 190.0 3.5 3.9e-56 189.9 3.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit FANCI_S4 PF14678.6 AAG08942.1 - 0.018 14.2 0.4 0.029 13.5 0.4 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 NlpE_C PF17185.4 AAG08942.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 NlpE C-terminal OB domain WSD PF15613.6 AAG08942.1 - 0.28 11.7 1.0 0.47 11.0 1.0 1.4 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif ATP-synt_B PF00430.18 AAG08943.1 - 1.7e-37 128.4 13.6 2.2e-37 128.1 13.6 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Apolipoprotein PF01442.18 AAG08943.1 - 1.1e-05 25.4 12.5 1.6e-05 24.9 12.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Kri1 PF05178.12 AAG08943.1 - 0.0079 16.7 0.2 0.0079 16.7 0.2 2.1 1 1 1 2 2 2 1 KRI1-like family HrpE PF06188.12 AAG08943.1 - 0.0088 15.9 14.7 0.01 15.7 14.7 1.2 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E DUF3552 PF12072.8 AAG08943.1 - 0.013 14.9 15.5 0.014 14.8 14.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) V-ATPase_G_2 PF16999.5 AAG08943.1 - 0.014 15.8 25.2 0.088 13.2 25.2 2.0 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Mt_ATP-synt_B PF05405.14 AAG08943.1 - 0.014 15.0 5.0 0.052 13.2 5.0 1.8 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) V_ATPase_I PF01496.19 AAG08943.1 - 0.027 12.4 0.2 0.031 12.2 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF883 PF05957.13 AAG08943.1 - 0.048 14.3 14.1 0.082 13.5 7.3 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MASE2 PF05230.11 AAG08943.1 - 0.048 13.7 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 MASE2 domain V-ATPase_G PF03179.15 AAG08943.1 - 0.054 14.0 21.2 0.049 14.2 16.4 1.9 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit YqaJ PF09588.10 AAG08943.1 - 0.056 13.6 0.3 0.072 13.2 0.3 1.2 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain TnpV PF14198.6 AAG08943.1 - 0.057 13.4 2.6 0.089 12.8 2.6 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV HAUS6_N PF14661.6 AAG08943.1 - 0.059 12.9 2.4 0.068 12.7 2.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ESM4 PF15952.5 AAG08943.1 - 0.14 12.6 3.0 0.24 11.8 3.0 1.4 1 1 0 1 1 1 0 Enhancer of split M4 family CdvA PF18822.1 AAG08943.1 - 0.14 12.0 8.9 0.55 10.1 4.1 2.7 1 1 1 3 3 3 0 CdvA-like coiled-coil domain RapA_C PF12137.8 AAG08943.1 - 0.17 10.8 8.2 0.24 10.4 8.2 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DivIVA PF05103.13 AAG08943.1 - 0.47 10.6 16.0 1.2 9.2 16.0 1.7 1 1 0 1 1 1 0 DivIVA protein DUF724 PF05266.14 AAG08943.1 - 0.51 10.1 8.4 0.68 9.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1917 PF08939.10 AAG08943.1 - 0.61 10.0 5.9 0.76 9.6 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) YtxH PF12732.7 AAG08943.1 - 0.86 10.2 12.0 0.24 12.0 5.0 2.3 1 1 1 2 2 2 0 YtxH-like protein CCDC-167 PF15188.6 AAG08943.1 - 1.2 9.5 8.6 43 4.5 8.6 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2570 PF10828.8 AAG08943.1 - 8.8 6.2 12.1 10 6.0 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) ATP-synt_C PF00137.21 AAG08944.1 - 2.8e-09 37.2 11.4 3.9e-09 36.7 11.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_A PF00119.20 AAG08945.1 - 1.4e-55 188.6 24.2 1.6e-55 188.3 24.2 1.0 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_I PF03899.15 AAG08946.1 - 1.9e-24 85.9 11.7 2.5e-24 85.5 11.7 1.2 1 0 0 1 1 1 1 ATP synthase I chain PsbN PF02468.15 AAG08946.1 - 0.48 10.3 0.1 0.48 10.3 0.1 1.9 2 1 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) ParBc PF02195.18 AAG08947.1 - 2e-30 104.9 1.1 4.3e-30 103.9 1.1 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 AAG08947.1 - 3.3e-17 62.0 1.2 3.3e-17 62.0 1.2 3.2 5 0 0 5 5 5 1 HTH domain found in ParB protein HTH_31 PF13560.6 AAG08947.1 - 0.00025 21.4 2.2 0.0019 18.5 0.2 3.1 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 AAG08947.1 - 0.00054 19.9 0.1 0.0034 17.4 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAG08947.1 - 0.0012 18.6 0.8 0.0037 17.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 AAG08947.1 - 0.0016 18.5 0.6 0.004 17.2 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_37 PF13744.6 AAG08947.1 - 0.0024 17.8 3.8 0.006 16.5 1.0 2.8 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAG08947.1 - 0.017 15.1 1.4 0.054 13.5 0.3 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAG08947.1 - 0.018 14.6 0.5 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AAG08947.1 - 0.047 13.5 0.1 0.17 11.7 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 AAG08947.1 - 0.051 13.8 0.0 4 7.7 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain SoPB_HTH PF18090.1 AAG08947.1 - 0.061 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Centromere-binding protein HTH domain AAA_31 PF13614.6 AAG08948.1 - 2.6e-64 216.4 0.1 4.2e-64 215.7 0.0 1.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 AAG08948.1 - 1.2e-25 90.0 0.0 1.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAG08948.1 - 2.9e-13 49.7 0.2 2.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 ATPase MipZ CBP_BcsQ PF06564.12 AAG08948.1 - 7.7e-12 45.2 0.0 2.6e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 AAG08948.1 - 4.3e-10 39.5 0.4 2.7e-09 36.9 0.3 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 AAG08948.1 - 7.2e-07 28.9 0.0 3.5e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AAG08948.1 - 8e-06 25.3 0.3 6.6e-05 22.2 0.3 2.1 1 1 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 AAG08948.1 - 7.5e-05 22.1 0.2 0.00046 19.6 0.1 2.0 2 0 0 2 2 2 1 VirC1 protein CLP1_P PF16575.5 AAG08948.1 - 0.00033 20.5 0.1 0.00067 19.5 0.1 1.5 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 AAG08948.1 - 0.00065 19.6 0.1 0.0058 16.4 0.1 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 AAG08948.1 - 0.015 15.0 0.2 0.057 13.1 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 AAG08948.1 - 0.06 12.9 0.1 0.83 9.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 AAG08948.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GidB PF02527.15 AAG08949.1 - 1.1e-62 210.6 0.0 1.4e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 AAG08949.1 - 0.00054 19.6 0.0 0.00082 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAG08949.1 - 0.0039 17.9 0.0 0.0071 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAG08949.1 - 0.04 14.6 0.0 0.07 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AAG08949.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF1281_C PF18406.1 AAG08949.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein GIDA PF01134.22 AAG08950.1 - 7.1e-170 565.3 0.0 9.3e-170 564.9 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 AAG08950.1 - 5.1e-77 258.8 0.0 7.3e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 AAG08950.1 - 1.3e-08 34.7 2.0 2.1e-08 34.0 2.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAG08950.1 - 4.2e-08 32.7 6.4 0.00013 21.2 2.0 3.0 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 AAG08950.1 - 1.9e-07 30.6 0.3 3.7e-07 29.7 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAG08950.1 - 0.00027 20.2 0.9 0.0021 17.4 0.9 2.0 1 1 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 AAG08950.1 - 0.00045 19.6 0.2 0.00087 18.6 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AAG08950.1 - 0.0049 15.6 4.0 0.0062 15.3 0.9 2.5 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 AAG08950.1 - 0.0061 16.2 1.6 1.4 8.4 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAG08950.1 - 0.015 15.9 0.4 0.033 14.7 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAG08950.1 - 0.046 13.0 0.0 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAG08950.1 - 0.053 12.7 0.3 0.14 11.4 0.3 1.7 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 AAG08950.1 - 0.42 10.9 2.9 2.6 8.3 0.4 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain MnmE_helical PF12631.7 AAG08952.1 - 3.5e-58 197.2 0.7 4.3e-58 196.9 0.7 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 AAG08952.1 - 2.7e-38 130.8 0.0 2.7e-37 127.6 0.0 2.3 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 AAG08952.1 - 2.7e-24 85.4 0.0 5.8e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAG08952.1 - 1.4e-09 37.7 0.0 2.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AAG08952.1 - 3.2e-06 27.3 0.1 0.0007 19.7 0.0 2.5 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 AAG08952.1 - 4.3e-06 26.2 0.0 6.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 AAG08952.1 - 0.00012 22.1 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 AAG08952.1 - 0.002 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Ras family ABC_tran PF00005.27 AAG08952.1 - 0.0032 18.0 0.0 0.0073 16.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 AAG08952.1 - 0.0054 17.0 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF4702 PF15774.5 AAG08952.1 - 0.039 12.9 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) DUF5129 PF17173.4 AAG08952.1 - 0.067 12.3 0.7 0.13 11.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Roc PF08477.13 AAG08952.1 - 0.071 13.3 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 AAG08952.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class YidC_periplas PF14849.6 AAG08953.1 - 3e-80 270.1 0.4 5.7e-53 180.6 1.1 2.1 1 1 1 2 2 2 2 YidC periplasmic domain 60KD_IMP PF02096.20 AAG08953.1 - 1.5e-61 207.1 7.2 2.4e-61 206.5 7.2 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF4381 PF14316.6 AAG08953.1 - 0.098 12.9 0.2 1 9.6 0.0 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4381) Ribonuclease_P PF00825.18 AAG08954.1 - 1.8e-31 108.5 0.0 2.1e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P Lipin_N PF04571.14 AAG08954.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 lipin, N-terminal conserved region Ribosomal_L34 PF00468.17 AAG08955.1 - 2.3e-25 88.3 11.4 2.5e-25 88.2 11.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Putative_PNPOx PF01243.20 AAO42617.1 - 9.1e-18 64.2 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 AAO42617.1 - 6e-10 39.1 0.3 1.6e-09 37.7 0.3 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 AAO42617.1 - 3.7e-05 24.2 0.0 6.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ABATE PF07336.11 AAO42617.1 - 0.1 13.3 4.0 0.14 12.8 0.6 2.2 2 0 0 2 2 2 0 Putative stress-induced transcription regulator AlaDh_PNT_C PF01262.21 ABG56537.1 - 7.6e-74 247.6 3.8 2e-73 246.2 2.5 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ABG56537.1 - 6.2e-43 146.4 1.2 1.4e-42 145.2 0.5 1.9 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 ABG56537.1 - 1.6e-06 27.6 0.0 0.084 12.2 0.0 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_Tnp_IS1 PF03811.13 ABG56537.1 - 0.056 13.2 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain ADH_zinc_N PF00107.26 ABG56537.1 - 0.14 12.2 1.6 2.4 8.1 0.1 2.7 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Molybdopterin PF00384.22 ABG56538.2 - 4.3e-35 121.5 0.0 9.3e-32 110.5 0.0 2.4 2 1 0 2 2 2 2 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 ABG56538.2 - 5.2e-18 64.8 0.5 1.3e-17 63.5 0.5 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Molydop_binding PF01568.21 ABG56538.2 - 1.6e-15 57.1 0.0 3.9e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Rieske_3 PF18465.1 ABG56538.2 - 0.3 11.4 1.0 2.2 8.6 1.0 2.5 1 1 1 2 2 2 0 Rieske 3Fe-4S PNTB_4TM PF12769.7 ABG56539.1 - 1.5e-35 121.5 9.1 1.7e-35 121.3 9.1 1.0 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch ABC2_membrane PF01061.24 ABG56539.1 - 0.014 14.8 5.8 0.016 14.6 5.8 1.0 1 0 0 1 1 1 0 ABC-2 type transporter Adeno_E3_14_5 PF04834.12 ABG56539.1 - 0.12 13.0 2.8 0.14 12.7 2.7 1.3 1 1 0 1 1 1 0 Early E3 14.5 kDa protein DUF3392 PF11872.8 ABG56539.1 - 0.12 12.7 5.4 0.075 13.3 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3392) DUF3754 PF12576.8 ABG56539.1 - 1.7 8.6 4.4 1.4 8.9 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3754) DUF485 PF04341.12 ABG56539.1 - 8.8 6.4 9.6 2.5 8.1 6.2 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF485 DUF1232 PF06803.12 ACI25436.1 - 2.7e-13 49.5 10.8 6.2e-13 48.3 10.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) FixQ PF05545.11 ADN93059.1 - 1e-09 38.2 0.3 4.7e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ ATP1G1_PLM_MAT8 PF02038.16 ADN93059.1 - 0.17 11.4 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family FixQ PF05545.11 ADN93060.1 - 8.1e-10 38.5 0.4 3.4e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ PCRF PF03462.18 ADN93061.1 - 3e-55 187.1 0.3 7.7e-55 185.8 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ADN93061.1 - 6.9e-42 142.0 0.6 1.4e-41 141.1 0.6 1.5 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 ADN93061.1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 MIR domain Tup_N PF08581.10 ADN93061.1 - 9.9 6.6 7.6 7.3 7.0 0.2 3.4 3 1 1 4 4 4 0 Tup N-terminal DUF3394 PF11874.8 ADN93062.1 - 2.3 7.9 5.2 1.1 8.9 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pseudomonas_aeruginosa_PAO1-ASM676v1/GCA_000006765.1_ASM676v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pseudomonas_aeruginosa_PAO1-ASM676v1/GCA_000006765.1_ASM676v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pseudomonas_aeruginosa_PAO1-ASM676v1/GCA_000006765.1_ASM676v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pseudomonas_aeruginosa_PAO1-ASM676v1/GCA_000006765.1_ASM676v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 03:59:26 2019 # [ok]